CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP033136	Vibrio campbellii strain 170502 plasmid pVCZS, complete sequence	0 crisprs	NA	0	0	0
CP033135	Vibrio campbellii strain 170502 chromosome II, complete sequence	0 crisprs	cas3,csa3,csx1,WYL	0	0	0
CP033134	Vibrio campbellii strain 170502 chromosome I, complete sequence	1 crisprs	cas3,DinG,csa3,WYL,csx1,RT,DEDDh,PD-DExK	2	1	5

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP033134_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033134_1

3000332-3000569

Orphan

Consensus_repeat	Method
CCTCCTTAGCTCAGTAGGTAGAGCAACGGACTGATAATCC	PILER-CR

2 spacers

The CRISPR arrays of CP033134_1

>merge|CP033134|1|3000332-3000569|PILER-CR
CTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGTCACCAGTTCGATTCCGGTAGTCGGCACCATTCTTTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCATATTTGGTGCACTTGCTTAAAGCAAGACACAAACAGAATAGTTCCTCCTTAGCTCAGTTGGTAGAGCGACGGACTGTTAATCCG

>CP033134|1|1|3000332-3000569|PILER-CR
CTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGT	CACCAGTTCGATTCCGGTAGTCGGCACCATTCTTTTGCCTCGA
TAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCG	GTGGTTCGATTCCGCCTCGAGGCACCATATTTGGTGCACTTGCTTAAAGCAAGACACAAACAGAATAGTTCCTCCTTA
GCTCAGTTGGTAGAGCGACGGACTGTTAATCCG

Protein	Signature genes	Signature genes Name	Protein_function
CP033134.1\|AYO10457.1\|2996234_2996954_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
CP033134.1\|AYO10469.1\|3018624_3019908_+\|dehydrogenase	unknown	unknown	gnl\|CDD\|200570
CP033134.1\|AYO10456.1\|2995194_2996223_-\|DNA-methylase	unknown	unknown	gnl\|CDD\|223971
CP033134.1\|AYO10460.1\|2998612_2999743_+\|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl\|CDD\|183271
CP033134.1\|AYO10998.1\|3003418_3004852_-\|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143421
CP033134.1\|AYO10468.1\|3018070_3018376_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99906
CP033134.1\|AYO10454.1\|2992795_2993968_+\|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl\|CDD\|235550
CP033134.1\|AYO10462.1\|3011686_3012937_-\|HD-GYP-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
CP033134.1\|AYO10464.1\|3014182_3014938_-\|chitin-disaccharide-deacetylase	unknown	unknown	gnl\|CDD\|235007
CP033134.1\|AYO10465.1\|3014955_3016278_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
CP033134.1\|AYO10463.1\|3013078_3014077_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380494
CP033134.1\|AYO10458.1\|2997157_2998234_+\|adenine-DNA-glycosylase	unknown	unknown	gnl\|CDD\|182805
CP033134.1\|AYO10467.1\|3016647_3017991_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
CP033134.1\|AYO10455.1\|2994171_2995092_-\|glutaminase	unknown	unknown	gnl\|CDD\|234880
CP033134.1\|AYO10459.1\|2998253_2998526_+\|Fe(2+)-trafficking-protein	unknown	unknown	gnl\|CDD\|180059
CP033134.1\|AYO10466.1\|3016288_3016600_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376749
CP033134.1\|AYO10451.1\|2991287_2991578_+\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
CP033134.1\|AYO10461.1\|3000896_3002522_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
CP033134.1\|AYO10453.1\|2992174_2992777_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
CP033134.1\|AYO10452.1\|2991637_2992069_+\|DUF4426-domain-containing-protein	unknown	unknown	gnl\|CDD\|379616

Protein	Function_ID	Function_description	E-value
CP033134.1\|AYO10457.1\|2996234_2996954_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.32707e-107
CP033134.1\|AYO10469.1\|3018624_3019908_+\|dehydrogenase	gnl\|CDD\|200570	cd10946, CE4_Mll8295_like, Putative catalytic NodB homology domain of uncharacterized Mll8295 protein encoded from Rhizobium loti and its bacterial homologs. This family is represented by a putative polysaccharide deacetylase Mll8295 encoded from Rhizobium loti. Although its biological function still remains unknown, Mll8295 shows high sequence homology to the catalytic domain of Streptococcus pneumoniae polysaccharide deacetylase PgdA (SpPgdA), which is an extracellular metal-dependent polysaccharide deacetylase with de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. Both Mll8295 and SpPgdA belong to the carbohydrate esterase 4 (CE4) superfamily. This family also includes many uncharacterized bacterial polysaccharide deacetylases.	1.05832e-73
CP033134.1\|AYO10456.1\|2995194_2996223_-\|DNA-methylase	gnl\|CDD\|223971	COG1041, COG1041, Predicted DNA modification methylase [DNA replication, recombination, and repair].	1.72952e-08
CP033134.1\|AYO10460.1\|2998612_2999743_+\|membrane-bound-lytic-murein-transglycosylase-MltC	gnl\|CDD\|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	4.87632e-149
CP033134.1\|AYO10998.1\|3003418_3004852_-\|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl\|CDD\|143421	cd07103, ALDH_F5_SSADH_GabD, Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like. Succinate-semialdehyde dehydrogenase, mitochondrial (SSADH, GabD, EC=1.2.1.24) catalyzes the NAD+-dependent oxidation of succinate semialdehyde (SSA) to succinate. This group includes the human aldehyde dehydrogenase family 5 member A1 (ALDH5A1) which is a mitochondrial homotetramer that converts SSA to succinate in the last step of 4-aminobutyric acid (GABA) catabolism. This CD also includes the Arabidopsis SSADH gene product ALDH5F1. Mutations in this gene result in the accumulation of H2O2, suggesting a role in plant defense against the environmental stress of elevated reactive oxygen species.	0
CP033134.1\|AYO10468.1\|3018070_3018376_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99906	cd05564, PTS_IIB_chitobiose_lichenan, PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N,N-diacetylchitobiose-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. In the chitobiose system, these subunits are expressed as separate proteins from chbA, chbB, and chbC of the chb operon (formerly the cel (cellulose) operon). In the lichenan system, these subunits are expressed from licA, licB, and licC of the lic operon. The lic operon of Bacillus subtilis is required for the transport and degradation of oligomeric beta-glucosides, which are produced by extracellular enzymes on substrates such as lichenan or barley glucan. The lic operon is transcribed from a gammaA-dependent promoter and is inducible by lichenan, lichenan hydrolysate, and cellobiose. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06674e-45
CP033134.1\|AYO10454.1\|2992795_2993968_+\|radical-SAM-family-heme-chaperone-HemW	gnl\|CDD\|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0
CP033134.1\|AYO10462.1\|3011686_3012937_-\|HD-GYP-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	3.8031e-71
CP033134.1\|AYO10464.1\|3014182_3014938_-\|chitin-disaccharide-deacetylase	gnl\|CDD\|235007	PRK02134, PRK02134, chitin disaccharide deacetylase.	4.67145e-126
CP033134.1\|AYO10465.1\|3014955_3016278_-\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
CP033134.1\|AYO10463.1\|3013078_3014077_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380494	cd06270, PBP1_GalS-like, ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism. Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism. Transcription of the galactose regulon genes is regulated by Gal iso-repressor (GalS) and Gal repressor (GalR) in different ways, but both repressors recognize the same DNA binding site in the absence of D-galactose. GalS is a dimeric protein like GalR,and its major role is in regulating expression of the high-affinity galactose transporter encoded by the mgl operon, whereas GalR is the exclusive regulator of galactose permease, the low-affinity galactose transporter. GalS and GalR are members of the LacI-GalR family of transcription regulators and both contain the type 1 periplasmic binding protein-like fold. Hence, they are homologous to the periplasmic sugar binding of ABC-type transport systems.	2.1442e-113
CP033134.1\|AYO10458.1\|2997157_2998234_+\|adenine-DNA-glycosylase	gnl\|CDD\|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
CP033134.1\|AYO10467.1\|3016647_3017991_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	1.26236e-154
CP033134.1\|AYO10455.1\|2994171_2995092_-\|glutaminase	gnl\|CDD\|234880	PRK00971, PRK00971, glutaminase; Provisional.	0
CP033134.1\|AYO10459.1\|2998253_2998526_+\|Fe(2+)-trafficking-protein	gnl\|CDD\|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	9.88866e-59
CP033134.1\|AYO10466.1\|3016288_3016600_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|376749	pfam02255, PTS_IIA, PTS system, Lactose/Cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIA PTS system enzymes. This family of proteins normally function as a homotrimer, stabilized by a centrally located metal ion. Separation into subunits is thought to occur after phosphorylation.	1.19402e-35
CP033134.1\|AYO10451.1\|2991287_2991578_+\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	1.0803e-59
CP033134.1\|AYO10461.1\|3000896_3002522_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	9.26374e-61
CP033134.1\|AYO10453.1\|2992174_2992777_+\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	3.57095e-123
CP033134.1\|AYO10452.1\|2991637_2992069_+\|DUF4426-domain-containing-protein	gnl\|CDD\|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	2.05857e-68

>CP033134.1|AYO10460.1|2998612_2999743_+|membrane-bound-lytic-murein-transglycosylase-MltC
MKKIAFIATALLMAGCSREFVEQIYDVNYEPTNRFANNLAELPGQFEKDTDALDALISSFSGNIKKRWGQREVKFAGKSNYVKYIDNYLSRAEVDFQKGVITIETVSPTEPQKHLKNAIITTLLTPDDPANVDLFSSKEIKLEGQPFLYKQVVDQDKKPIQWSWRANRFADYLIANQVKTKDVDFKKAYYVEIPMVEDHFSQRSYQYADIVRRASKKYDIPEDLIYAIIKTESSFNPYAVSWANAYGLMQVVPKTAGRDVFKLVKNRSGQPSPEYLFNPENNIDTGTAYFYILKNRYLKDVQHPTSLEYSMISAYNGGTGGVLNTFHRTDRKRAMQDLNSLQPNQVYWALTKKHPNAEARRYLEKVTNFKKEFNAG
>CP033134.1|AYO10459.1|2998253_2998526_+|Fe(2+)-trafficking-protein
MSRTVFCARLKKEGEGLDFQLYPGELGKRIFDNISKEAWAQWQHKQTMLINEKKLNMMDPEHRKQLETEMVNFLFEGKDVHIEGYTPPSE
>CP033134.1|AYO10458.1|2997157_2998234_+|adenine-DNA-glycosylase
MTPFASAILEWYDAYGRKDLPWQQNKTAYSVWLSEIMLQQTQVTTVIPYYQRFLERFPTVVDLANAEQDEVLHLWTGLGYYARARNLHKAAKEVAHKYNGEFPLDLEQMNALPGIGRSTAAAVLSSVYKQPHAILDGNVKRTLSRCFAVDGWPGQKKVENQLWEIAETHTPQTDVDKYNQAMMDMGAMMCTRSKPKCTLCPVNELCVAKKQGNVLDYPGKKPKKDKPVKQTRFVMLHHKNGDSHEVWLEQRPQTGIWGGLFCFPQTEHIDVESDIELLLEQRGIQANDIRHQETLITFRHTFSHYHLDITPILIDLSKQPNVVMEGNKGLWYNLSKPEEVGLAAPVKLLLEALPHELR
>CP033134.1|AYO10457.1|2996234_2996954_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSEVTTNEYNEDGKMIRKIRSFVRREGRLTKGQENAMNECWPTMGIDYKAELLDWKEVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFIGIEVHSPGVGACLADAREAGITNLRVMCHDAVEVFEHMIPNGSLATLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLILNEGIFHMATDWENYAEHMIEIMNQAPGFENIAEEGDFIPRPEERPLTKFEARGHRLGHGVWDIKFKRTA
>CP033134.1|AYO10456.1|2995194_2996223_-|DNA-methylase
MYHYAILANPGHNRIYFDSAMTIACSELKAILASEGVEVTEIGNKDVGLPAALVFSCETELSEAQAGKIAASSIYYALFEVREDGLLRPIQAPAFNTFPESMSQILRYTGKTNEQFTRLMVNLGVSAANTGSAQLTLMDPMCGKGTTLFEGLIHGLNVVGVEINQKWVQEIQTFIVKFMKNGRFKHKVSKEKRTSGGKKVADGFVVEAAADKDDYNKGNLQTMKLYSADTRIADQVVKKNSVDVMVSDLPYGVQHGSKNAKDSKLNRSPLELLKEALPAWKVVLKKQGSVVLSFNEFTLKWKDVAALFEEQGWKVLSEEPYIGYLHRVDQSINRNIIVAIKP
>CP033134.1|AYO10455.1|2994171_2995092_-|glutaminase
MKPTAQILTDILAEVRPLIGQGKVADYIPALAKVPNTKLGIAVYTNEGEVIKAGDAEESFSIQSISKALSLTLAMCLYKQEEIWCRVGKEPSGQAFNSMIQLEMEQGIPRNPFINAGAIVVADLLQSRLSAPRQRLLEFARQLSGDTHIVYDKVVAASEMMHGDRNAAIAYLMRSFGNFENEVIPVLQNYFHACALKMSCVDLAKTFSYLANKGTSVQTGKPVVSPTQTKQLNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPELDASGNSLAGTKALELLAERIGRSIF
>CP033134.1|AYO10454.1|2992795_2993968_+|radical-SAM-family-heme-chaperone-HemW
MLTPPALSLYVHIPWCVQKCPYCDFNSHALKAEIPEEEYINALLEDLDTDIEKYRLNEAPRPLHSIFIGGGTPSLISAEGIERLLKGIEARIPFKPEIEITMEANPGTIEAERFVGYRKAGVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIGLNSFNLDLMHGLPDQSIEQALADLDKAIELAPPHLSWYQLTIEPNTMFYYKPPTLPDDDDLWDIFEQGHEKLAAAGYVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIVRTTKVKHPRGYLMAYQNMVKPYLDSEQLVADEDRPFEFFMNRFRLMEACPKQDYTDTTGLPLSSIQETIDWALEMGYLSETETHWQITEKGKLFLNDLLEAFMAEEE
>CP033134.1|AYO10453.1|2992174_2992777_+|XTP/dITP-diphosphatase
MKKIVLATGNQGKVREMADLLSDFGFEVLAQSEFNVSEVAETGTTFIENAIIKARHAAQETGLPAIADDSGLEVDFLKGAPGIYSARYAGEKASDQENLEKLLKAMEGVPEAERTARFHCVLVLMRHENDPTPIVCHGKWEGRILTEAHGENGFGYDPIFFVPEDNCASAELEPARKKQLSHRGKALKSLFAQLSEQVSQ
>CP033134.1|AYO10452.1|2991637_2992069_+|DUF4426-domain-containing-protein
MSKWITALLISLLSLPSMAGQFKTMKDIEVHYIAFNSTFLTPKIARSYDIKRNGYNAVLNISVLDSASLGKPAVEAKISGQAKNLIGQTQKLTFREVKEGDAIYYLAELGITNEETFTFDIDVKAGNKGSGKLKFTQKFYVEE
>CP033134.1|AYO10451.1|2991287_2991578_+|YggU-family-protein
MSEAVWHDGEDVVLRLYIQPKASRDKIVGLHGEELKIAITAPPVDGKANAHLTKFLAKQFKVAKGLVHIEKGELGRHKQIRIESPVQIPTEIKAII
>CP033134.1|AYO10461.1|3000896_3002522_+|methyl-accepting-chemotaxis-protein
MKLKTQAYLLSAIILVALLALTATGLWTLRVASNLDNKARVTELFKSAYSILTEVEQMAVEGKMPEDEAKALATRLLRNNIYKDNEYVYVADENMIFVAAPLDPQLHGTSFHDFRDGDGNSVGQLILDVLGRKTGQIVEYTWTQKQPDGTVEEKHSIAEKTPHWNWVVGTGIGFNEVNARFWSTAQWQLALCLAIAGAILGGLIISIRKMLNLLGGEPNDVREAVQAVAQGNIQASFEHTAPKDSIYGAVQEMSQSLAKMVTNLDESMHALRSELSAVESRSNSIADLTMSQQQSTAMIATAMTEMASSANHVASSASDTAHNTDEADKQSQHTQSLIHSTVDNIQGLATQLNTASKAVADLDQDVNSIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQDSTKEIQQMISNLQEGSRNAIHTMEICAETSESTVTESMNASEALQQIVTALESITAMSQQIATAAAEQTQVSDDIAHRINLIEESGSQLNAVVTESQSSTQTLASLADELEGWVNKFSVKH
>CP033134.1|AYO10998.1|3003418_3004852_-|NAD-dependent-succinate-semialdehyde-dehydrogenase
MQQIQSETLRVLFENLSSQDGIAVINPATEQELIRLKPSSLDELDVQIEACKSAQVEWAKLSAKARSASLKKWFQLLVEHTEDIANIITLEQGKPLTESRGEVAYGASFVEWFAEEAKRAYGEVIPAPAIDRRLSTIKQPIGVCAAITPWNFPIAMITRKAAPALAAGCGMIIKPSELTPLTALAVVELAHQAGIPKALLTTVVSEQAAEFGLVLSTDPRIKKISFTGSTRVGKILMKQASDTVKAASMELGGNAPFIVFDDADLEAAANGLIASKFRNAGQTCVCTNRLYVHQSVKEAFLAKILDKAAGLTVGNGLEENTTLGPVITMASKHRLEAVIDQAVQEGAKILNQPQKRSGRFMEPVILDNVEQGMAIVQQELFGPVLPVISFDDDEQVLSMANDTEYGLACYFYTDSLKRIIKFSEGLEYGMVGVNEGIISTEVAPFGGIKESGIGREGAKQGMDEYLETKYICLGGLS
>CP033134.1|AYO10462.1|3011686_3012937_-|HD-GYP-domain-containing-protein
MAAIKLTVDRIQPGLHIRLPLKWNDHPFLLNSFKIKDQEQVEMIRHLGVKFVYFNPDQSDASPLPANQPQAEVKQVHALDLEAQKLWQEKQKRIEKLSAYRRRVIQCEKEFERSLARMRSVMTKIRNRPADAVGEAKQLIDDIVEKLMCDDNVTLHLMNGKNEFEDIYFHSLNVAVIAMMIGRAKGYSAEQLKALSFAALFHDMGKIKIPTAILRKQVPLNEPESNYLKLHTKYGLDMANQIEGFPESAKTVIVQHHELRDGSGYPEGLKGDEIDELAQVIIVANAFDNLCHTPVAAEQKIPYTALSHLYKNCKHLYKEENLTILIKFMGVFPPGTVVQLSNNMVGLVISVNASHLLFPNVLVYDPAVPRTQAPIIDLASKDIKIVNAIHPSKLPEKIKEYLNPRSRISYFFDSDE
>CP033134.1|AYO10463.1|3013078_3014077_-|LacI-family-DNA-binding-transcriptional-regulator
MARIKDVAELAGVNRSTVSRIINGEGKFRDETRKKVEAAMAELNYRPSAIARSLATSSSNMVGLLVTYYTGGFFGEMMEQVQTELDMHKKFLITAQGHHSAEGEREAIQRFNDLRCDGYVLHSRYLSDDDLRELAKLPTPFVLLDRYVEGIEERCVTFNHHHASRIAVEHLIAGGHKNIACITGPSQRHNSLLRKLGYVDAMKTAGIDIDESWCEEGNYGRQSGYDAMAAIYHRHPEVTAVFSCSEEMTVGAMQFLHEKRISVPEQISLVSFDSVDLCESLYPTVSAVHFPISDMARVAVQTLMGLIKDQQLHTKPVFEAELKLRKADRTLS
>CP033134.1|AYO10464.1|3014182_3014938_-|chitin-disaccharide-deacetylase
MKVIFNADDFGLTPGVNKGIVKAHQQGVVRSTTMMVGMDAEEHAVELAKQNPNLKIGVHLRFTAGAPVAGHPNLTNGQTQFVSYDELWKKQDFEEEVVYQEAIAQVEAFLKLGLSLSHLDSHHHAHTHPQLLPVIRKVAQKYKVPLRGSGLCHTESKVKYYFTDEFYDQGVSLDGIMKHLLSLKAKYDVVEVMCHPAEADQSLLLKSSYALQRELELQVLTSPILKQEFAQHGMTVTDYSALISSSKVVSV
>CP033134.1|AYO10465.1|3014955_3016278_-|6-phospho-beta-glucosidase
MPRNAIKLAIIGGGSSYTPELVEGVIKRLEFLPVKQMHFVDIESGAEKLEIIKGLAQRMVDKAGADIEIKASFDRRDAIKDADFVMTQFRVGGLAARANDERIPIKYDVIGQETTGPGGFAKALRTIPVILDICKDIEELAPNAWMLNFTNPAGLVSEAVSKYTNVKSIGLCNVPVSMEMMIAEMMDCEPKELQLEFAGLNHLVWVLKAWLKGKDITQTVLEKVGDGANFSMKNIWEEPWDPAFLKALGAIPCPYHRYFYQTDAMLAEEKQSAGEQGTRAEQVMATESALFKLYQDPNLDHKPKELEERGGAYYSDASLNLVDSIYNNRNSIHVVNVLNNGAINGLPDDAVIECSAVIGSWGAKPLAVGELSSNIKGLLHQVKAYEQLAIEAAVEGSYDKALMALTNNPLVPDIGRAKSILDEILAVNAPYLPQFKLTTL
>CP033134.1|AYO10466.1|3016288_3016600_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MEQELVVMEIICNAGEARSLSYEALRLSREKDFSAAEEKLSQARECINKAHLIQTQLIEEDQGEGKVPMTLVMVHAQDHLMTTILAQEMAVEIVALNKQLAEK
>CP033134.1|AYO10467.1|3016647_3017991_-|PTS-sugar-transporter-subunit-IIC
MDSMKLYDAIIGIVEKHIAPIAAKVGNQPHVRAMRDGFIVAMPFIIVGSFILIFAFPPFAEDTTFTLGRVWLDFATTHFDTIMMPFNMSMGIMTIFVSLGVAYSLAKAYKMDGITSAVLSLMSFLLVAAPAKDGALAMKHMGGTGIFTAVMCAFFAVELYRFMKKHNITIRMPEQVPPAIARSFEVLLPVLAIFLTLYPLSIFVQTQYDMLIPDAVMAMFKPLISASNTLPAIIGALLVCQLLWFAGIHGAAIVVGLLSPIFLTNISANIDAFVAGQPIPNVFTQPFWDFYIFIGGSGATLALVMLMSFSRSAHLKSIGRMSAVPGFFQINEPVIFGSPVVMNPILFIPFVFAPIVNATIAYFAVQLGFVGMGVATTPWTTPALIGASWGSGWTFSPVLLVIGLLILDLFIYLPFFKMFEKQVMEQELPTSKESKDAEQPSGEGVTA
>CP033134.1|AYO10468.1|3018070_3018376_-|PTS-sugar-transporter-subunit-IIB
MKKILLCCSAGMSTSMLVKKMEQAAEKQGLECKIDALSVNVFDEAIKEYDVCLLGPQVRFQLEELRKTAQEHGKNIDAISPQAYGMMKGEEVLQQALELIN
>CP033134.1|AYO10469.1|3018624_3019908_+|dehydrogenase
MKLTKLAMVTLLGSALSQFSYAQEAPKGTIYLTFDDGPINASIDVINVLNQQGVKGTFYFNAWHLDGIGDENEDRALEALKLALDTGHIVANHSYAHMIHNCVEEFGPNSGAECNATGDHQINSYQDPVYDAGTFAENLAVLERYLPNINSYPNYRGEEFARLPYTNGWRVTKNFKADGLCATSDDLKPWEPGYVCDTDNPSNSVKASIEVQNILANKGYQTHGWDLDWAPENWGIAMPANSLTEAEPFLGYVDAALNSCAPTTINPINSKAQEFPCGTPLHADKVIVLTHEFLFEDGKRGMGATKNLPKLAKFIQIAKEAGYVFDTMDNYTPVWQVGQAYVAGDYVTHSGTVYKAVTTHVAQQDWAPSSTSSLWTNADPATNWTLNVAYEAGDVVTYQGIRYLVNVPHVSQADWTPSTQNTLFTAL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	CP033134.1	3000020-3000062	0	1.0
CP033134_1	1.2\|3000459\|78\|CP033134\|PILER-CR	3000459-3000536	78	CP033134.1	3000104-3000181	18	0.769

1. spacer 1.1|3000374|43|CP033134|PILER-CR matches to position: 3000020-3000062, mismatch: 0, identity: 1.0

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccattctttt	Protospacer
*******************************************

2. spacer 1.2|3000459|78|CP033134|PILER-CR matches to position: 3000104-3000181, mismatch: 18, identity: 0.769

tcgtgtcggtggttcgattccgcctcgaggcaccatatttggtgcacttgcttaaagcaa	CRISPR spacer
tcgtgtcggtggttcgattccgcctcgaggcaccatatttggtgcacttgcttaaagcaa	Protospacer
************************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_LN868946	Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence	103819-103861	5	0.884
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NC_021742	Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence	35424-35466	5	0.884
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	296497-296539	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	KU052038	Escherichia phage SerU-LTIIb, partial genome	1162-1204	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	KU052038	Escherichia phage SerU-LTIIb, partial genome	3068-3110	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	LN997803	Escherichia coli phage phi467	15122-15164	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP023526	Cedecea neteri strain FDAARGOS_392 plasmid unnamed, complete sequence	1925-1967	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP022660	Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence	52074-52116	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP045061	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence	52080-52122	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP045054	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence	52085-52127	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP045058	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence	52084-52126	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	MH791411	UNVERIFIED: Escherichia phage Ecwhy_1, complete genome	13641-13683	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	MH494197	Escherichia phage CMSTMSU, complete genome	196768-196810	6	0.86
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NZ_CP054057	Scandinavium goeteborgense strain CCUG 66741 plasmid pSg66741_1, complete sequence	85813-85855	7	0.837
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	KY653118	Morganella phage IME1369_01, complete genome	694-736	7	0.837
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NC_049942	Escherichia phage JLK-2012, complete sequence	23522-23564	10	0.767
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	LC494302	Escherichia phage SP27 DNA, complete genome	76609-76651	11	0.744
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	17115-17157	11	0.744
CP033134_1	1.1\|3000374\|43\|CP033134\|PILER-CR	3000374-3000416	43	NC_027364	Escherichia phage PBECO 4, complete genome	207828-207870	11	0.744

1. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_LN868946 (Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence) position: , mismatch: 5, identity: 0.884

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccatcaagtc	Protospacer
*************************************.   *.

2. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NC_021742 (Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.884

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagccggcaccaatcaagt	Protospacer
***************************.******** **   *

3. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccatatgcgg	Protospacer
************************************* . .

4. spacer 1.1|3000374|43|CP033134|PILER-CR matches to KU052038 (Escherichia phage SerU-LTIIb, partial genome) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccatatgcgg	Protospacer
************************************* . .

5. spacer 1.1|3000374|43|CP033134|PILER-CR matches to KU052038 (Escherichia phage SerU-LTIIb, partial genome) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccatatgcgg	Protospacer
************************************* . .

6. spacer 1.1|3000374|43|CP033134|PILER-CR matches to LN997803 (Escherichia coli phage phi467) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccatatgcgg	Protospacer
************************************* . .

7. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP023526 (Cedecea neteri strain FDAARGOS_392 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccagaatgcg	Protospacer
************************************   * .

8. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP022660 (Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccacttacga	Protospacer
************************************.*. .

9. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP045061 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccacttacga	Protospacer
************************************.*. .

10. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP045054 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccacttacga	Protospacer
************************************.*. .

11. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP045058 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccacttacga	Protospacer
************************************.*. .

12. spacer 1.1|3000374|43|CP033134|PILER-CR matches to MH791411 (UNVERIFIED: Escherichia phage Ecwhy_1, complete genome) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcacaaatcagcc	Protospacer
********************************** * **  ..

13. spacer 1.1|3000374|43|CP033134|PILER-CR matches to MH494197 (Escherichia phage CMSTMSU, complete genome) position: , mismatch: 6, identity: 0.86

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcacaaatcagcc	Protospacer
********************************** * **  ..

14. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NZ_CP054057 (Scandinavium goeteborgense strain CCUG 66741 plasmid pSg66741_1, complete sequence) position: , mismatch: 7, identity: 0.837

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgattccggtagtcggcaccaaatgcgg	Protospacer
************************************  . .

15. spacer 1.1|3000374|43|CP033134|PILER-CR matches to KY653118 (Morganella phage IME1369_01, complete genome) position: , mismatch: 7, identity: 0.837

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
agtaggtcaccagttcgactccggtagccggcaccatattaaa	Protospacer
******************.********.********* .*

16. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NC_049942 (Escherichia phage JLK-2012, complete sequence) position: , mismatch: 10, identity: 0.767

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
atcaggtcgccagttcgattccggtagccggcaccatatgcgg	Protospacer
* .*****.******************.********* . .

17. spacer 1.1|3000374|43|CP033134|PILER-CR matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 11, identity: 0.744

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
gaaaggtcaccagttcgattccggtagtcggcacaaaataaag	Protospacer
.. ******************************* *  .

18. spacer 1.1|3000374|43|CP033134|PILER-CR matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 11, identity: 0.744

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
gaaaggtcaccagttcgattccggtagtcggcacaaaataaag	Protospacer
.. ******************************* *  .

19. spacer 1.1|3000374|43|CP033134|PILER-CR matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 11, identity: 0.744

agtaggtcaccagttcgattccggtagtcggcaccattctttt	CRISPR spacer
gaaaggtcaccagttcgattccggtagtcggcacaaaataaag	Protospacer
.. ******************************* *  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

608156 : 615228

Faustovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYO08421.1\|608156_609371_+	IscS subfamily cysteine desulfurase	A0A1X7C038	Faustovirus	7.4e-32	30.2
AYO08422.1\|609408_609792_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
AYO08423.1\|609865_610189_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	1.0e-25	51.4
AYO08424.1\|610244_610760_+	co-chaperone protein HscB	NA	NA	NA	NA
AYO08425.1\|610781_612635_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	2.7e-110	40.4
AYO08426.1\|612648_612987_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
AYO08427.1\|613036_613231_+	Fe-S assembly protein IscX	NA	NA	NA	NA
AYO08428.1\|613403_614702_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	9.1e-36	34.7
AYO08429.1\|614802_615228_+	nucleoside-diphosphate kinase	L7Y4C4	Megavirus	2.1e-21	40.6

DBSCAN-SWA_2

689928 : 696618

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYO08487.1\|689928_691068_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.9e-62	41.4
AYO08488.1\|691085_692336_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.6e-99	47.9
AYO08489.1\|692463_692913_+	transcriptional regulator NrdR	NA	NA	NA	NA
AYO08490.1\|692920_694045_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.2e-44	35.4
AYO08491.1\|694056_694710_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.3e-34	38.0
AYO08492.1\|694868_695978_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.6e-63	39.6
AYO08493.1\|696147_696618_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.7e-32	49.3

DBSCAN-SWA_3

2001864 : 2052310

Staphylococcus_phage(55.56%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYO09563.1\|2001864_2002833_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09564.1\|2002869_2003358_-	hypothetical protein	NA	NA	NA	NA
AYO09565.1\|2003354_2003807_-	hypothetical protein	NA	NA	NA	NA
AYO09566.1\|2004031_2004487_-	NUDIX domain-containing protein	NA	NA	NA	NA
AYO10946.1\|2004539_2004665_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09567.1\|2004746_2005715_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09568.1\|2005749_2006187_-	hypothetical protein	NA	NA	NA	NA
AYO09569.1\|2006376_2006679_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AYO09570.1\|2006666_2006924_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AYO10947.1\|2007005_2007095_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO10948.1\|2007615_2007756_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09571.1\|2007733_2008243_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYO09572.1\|2008245_2009139_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.5e-55	44.3
AYO09573.1\|2009604_2009937_-	hypothetical protein	NA	NA	NA	NA
AYO09574.1\|2009936_2010572_-	hypothetical protein	NA	NA	NA	NA
AYO09575.1\|2010687_2010798_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09576.1\|2010804_2012145_-	Fic family protein	A0A1V0E025	Clostridioides_phage	1.1e-20	28.4
AYO09577.1\|2012290_2012506_-	hypothetical protein	NA	NA	NA	NA
AYO09578.1\|2012446_2013415_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09579.1\|2013456_2014128_-	hypothetical protein	NA	NA	NA	NA
AYO10949.1\|2014156_2014273_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09580.1\|2014263_2014716_-	hypothetical protein	NA	NA	NA	NA
AYO09581.1\|2014912_2015161_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AYO09582.1\|2015150_2015441_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	9.1e-21	56.4
AYO10950.1\|2016007_2016118_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09583.1\|2016214_2017183_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09584.1\|2017565_2017697_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09585.1\|2018241_2018742_-	hypothetical protein	NA	NA	NA	NA
AYO09586.1\|2018910_2019036_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09587.1\|2019077_2019323_+	plasmid maintenance protein CcdB	NA	NA	NA	NA
AYO09588.1\|2019322_2019640_+	plasmid maintenance protein CcdB	NA	NA	NA	NA
AYO09589.1\|2019930_2020173_-	NUDIX domain-containing protein	NA	NA	NA	NA
AYO10951.1\|2020200_2020326_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09590.1\|2020407_2021376_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09591.1\|2021414_2021702_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AYO09592.1\|2021698_2021980_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AYO09593.1\|2022092_2022986_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.5e-55	44.3
AYO09594.1\|2023819_2023951_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09595.1\|2024436_2024529_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO10952.1\|2024543_2024786_-	hypothetical protein	NA	NA	NA	NA
AYO10953.1\|2025016_2025106_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09596.1\|2025160_2025478_-	hypothetical protein	NA	NA	NA	NA
AYO09597.1\|2025626_2025737_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09598.1\|2025742_2026447_-	hypothetical protein	NA	NA	NA	NA
AYO09599.1\|2026686_2027118_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYO10954.1\|2027216_2027306_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09600.1\|2027836_2027965_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO10955.1\|2028383_2028494_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09601.1\|2028590_2029559_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09602.1\|2029644_2029893_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AYO09603.1\|2029882_2030173_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	9.1e-21	56.4
AYO09604.1\|2030191_2030302_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09605.1\|2030298_2030613_-	DNA-binding transcriptional regulator	NA	NA	NA	NA
AYO09606.1\|2030599_2030932_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AYO09607.1\|2031156_2031798_-	hypothetical protein	NA	NA	NA	NA
AYO09608.1\|2033478_2033601_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09609.1\|2033597_2034506_-	aminoglycoside phosphotransferase	NA	NA	NA	NA
AYO09610.1\|2034739_2034982_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AYO09611.1\|2034989_2035289_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AYO09612.1\|2035352_2035469_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09613.1\|2035459_2036233_-	nuclease	A0A2R2ZH57	Clostridioides_phage	6.8e-31	35.5
AYO09614.1\|2036370_2037000_-	type B chloramphenicol O-acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	3.4e-28	39.3
AYO09615.1\|2037056_2037950_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.5e-55	44.3
AYO10956.1\|2038294_2038411_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09616.1\|2038410_2038791_-	DUF4087 domain-containing protein	NA	NA	NA	NA
AYO09617.1\|2038818_2038929_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09618.1\|2038925_2039438_-	hypothetical protein	NA	NA	NA	NA
AYO09619.1\|2039596_2039791_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09620.1\|2039712_2040072_-	hypothetical protein	NA	NA	NA	NA
AYO10957.1\|2040091_2040181_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09621.1\|2040222_2040723_-	hypothetical protein	NA	NA	NA	NA
AYO09622.1\|2040771_2040885_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09623.1\|2040878_2041589_-	hypothetical protein	NA	NA	NA	NA
AYO10958.1\|2041621_2041732_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09624.1\|2041828_2042797_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO10959.1\|2042822_2043155_-	hypothetical protein	NA	NA	NA	NA
AYO09625.1\|2043169_2043649_-	hypothetical protein	NA	NA	NA	NA
AYO10960.1\|2044337_2044514_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09626.1\|2044544_2045513_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09627.1\|2045538_2046051_-	hypothetical protein	NA	NA	NA	NA
AYO09628.1\|2046079_2046202_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO10961.1\|2046582_2046744_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09629.1\|2046784_2047057_+	DUF1778 domain-containing protein	NA	NA	NA	NA
AYO09630.1\|2047053_2047551_+	N-acetyltransferase	NA	NA	NA	NA
AYO10962.1\|2047584_2047674_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09631.1\|2047715_2048216_-	hypothetical protein	NA	NA	NA	NA
AYO10963.1\|2048264_2048354_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09632.1\|2048450_2049122_+	hypothetical protein	NA	NA	NA	NA
AYO10964.1\|2049170_2049296_-	DUF3265 domain-containing protein	NA	NA	NA	NA
AYO09633.1\|2049377_2050346_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	5.7e-43	37.5
AYO09634.1\|2050371_2051097_-	NYN domain-containing protein	NA	NA	NA	NA
AYO09635.1\|2051185_2051401_-	hypothetical protein	NA	NA	NA	NA
AYO09636.1\|2051341_2052310_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.2e-42	37.2

DBSCAN-SWA_4

2397937 : 2406045

Vibrio_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYO10977.1\|2397937_2398138_-	hypothetical protein	U3PDF9	Vibrio_phage	5.9e-11	57.9
AYO09935.1\|2399902_2400112_-	hypothetical protein	A0A2I7RNH0	Vibrio_phage	4.2e-12	54.2
AYO09936.1\|2400108_2400519_-	hypothetical protein	A0A2I7RNG1	Vibrio_phage	2.4e-35	57.6
AYO09937.1\|2400577_2400790_-	hypothetical protein	U3PFJ1	Vibrio_phage	1.5e-20	67.1
AYO09938.1\|2400943_2401606_+	chromosome partitioning protein ParA	A0A166YHA0	Vibrio_phage	9.6e-58	54.2
AYO09939.1\|2402010_2402964_-	hypothetical protein	NA	NA	NA	NA
AYO09940.1\|2402963_2404097_-	DUF3696 domain-containing protein	NA	NA	NA	NA
AYO09941.1\|2404086_2406045_-	DUF262 domain-containing protein	A0A0R6PKN1	Moraxella_phage	3.3e-13	29.1

DBSCAN-SWA_5

2926294 : 2939876

uncultured_Mediterranean_phage(22.22%)

integrase,tRNA

attL 2916452:2916466|attR 2941740:2941754

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2916452:2916466	attL	NA	NA	NA	NA
AYO10387.1\|2926294_2927635_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	8.5e-21	23.5
AYO10388.1\|2927807_2930393_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	22.7
AYO10389.1\|2930481_2931468_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.9e-36	35.2
AYO10390.1\|2931548_2932472_-	LysM peptidoglycan-binding domain-containing protein	D7RWE0	Brochothrix_phage	2.4e-06	36.4
AYO10391.1\|2932486_2933113_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.8e-37	53.9
AYO10392.1\|2933112_2933889_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	5.4e-68	54.1
AYO10393.1\|2933888_2934932_-\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
AYO10394.1\|2934977_2935454_-	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
AYO10395.1\|2935468_2936179_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	A0A2H4UTB4	Bodo_saltans_virus	1.1e-06	23.1
AYO10396.1\|2936180_2936462_-	cell division protein FtsB	NA	NA	NA	NA
AYO10397.1\|2936855_2938157_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	3.5e-136	60.3
AYO10398.1\|2938235_2939876_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.6e-154	52.1
2941740:2941754	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage