CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP033341	Salmonella enterica subsp. enterica serovar Enteritidis strain CFSAN076214 plasmid pCFSAN076214_1, complete sequence	0 crisprs	NA	0	0
CP033342	Salmonella enterica subsp. enterica serovar Enteritidis strain CFSAN076214 plasmid pCFSAN076214_2, complete sequence	0 crisprs	cas14j	0	4
CP033340	Salmonella enterica subsp. enterica serovar Enteritidis strain CFSAN076214 chromosome, complete genome	2 crisprs	PD-DExK,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,csa3,DEDDh,DinG	7	9

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 727

Morganella_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP79415.1\|304_727_-	peptidase	A0A1W6JNS2	Morganella_phage	2.0e-29	52.4

DBSCAN-SWA_2

17911 : 18469

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP79436.1\|17911_18469_-	hypothetical protein	Q9EV15	Enterobacteria_phage	5.8e-24	37.4

DBSCAN-SWA_3

25301 : 27206

Stx_converting_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP79443.1\|25301_25688_+	NirD/YgiW/YdeI family stress tolerance protein	A0A1I9LJU6	Stx_converting_phage	3.0e-27	46.9
AYP79444.1\|25740_25902_+	recombinase	NA	NA	NA	NA
AYP79480.1\|26228_27206_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	1.2e-101	60.1

DBSCAN-SWA_4

31057 : 55585

Escherichia_phage(33.33%)

transposase,integrase

attL 24480:24492|attR 39072:39084

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
24480:24492	attL	NA	NA	NA	NA
AYP79451.1\|31057_31840_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.6e-51	91.1
AYP79452.1\|31848_32562_+	EAL domain-containing protein	NA	NA	NA	NA
AYP79453.1\|32565_33075_+	CaiF/GrlA family transcriptional regulator	NA	NA	NA	NA
AYP79454.1\|33068_33554_+	hypothetical protein	NA	NA	NA	NA
AYP79455.1\|33830_34118_-	hypothetical protein	NA	NA	NA	NA
AYP79456.1\|34273_34834_+	inverse autotransporter beta-barrel domain-containing protein	NA	NA	NA	NA
AYP79457.1\|34900_35251_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	1.9e-44	80.5
AYP79458.1\|35307_35733_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.4e-24	50.4
AYP79459.1\|35859_36510_-	SPI-2 type III secretion system effector cysteine hydrolase SpvD	NA	NA	NA	NA
AYP79460.1\|36771_37497_-	type III secretion system effector phosphothreonine lyase SpvC	NA	NA	NA	NA
AYP79461.1\|37777_39553_-	SPI-2 type III secretion system effector NAD(+)--protein-arginine ADP-ribosyltransferase SpvB	NA	NA	NA	NA
39072:39084	attR	NA	NA	NA	NA
AYP79462.1\|39734_40502_-	virulence protein SpvA	NA	NA	NA	NA
AYP79463.1\|40675_40840_-	lysozyme	A0A0M4R365	Salmonella_phage	3.3e-12	63.0
AYP79464.1\|41013_41907_-	virulence genes transcriptional activator SpvR	NA	NA	NA	NA
AYP79465.1\|42514_43552_+\|transposase	IS630 family transposase	NA	NA	NA	NA
AYP79466.1\|43740_44766_-	AAA family ATPase	NA	NA	NA	NA
AYP79467.1\|44698_46363_-\|transposase	IS481 family transposase	NA	NA	NA	NA
AYP79468.1\|46346_46907_-	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.5e-32	43.2
AYP79469.1\|47113_47854_-	carbonic anhydrase	NA	NA	NA	NA
AYP79470.1\|48508_48997_-	cytoplasmic protein	NA	NA	NA	NA
AYP79471.1\|49254_50370_+	DNA-binding protein	NA	NA	NA	NA
AYP79481.1\|50455_50872_+	hypothetical protein	O64348	Escherichia_phage	8.2e-07	42.9
AYP79472.1\|51055_51391_+	hypothetical protein	NA	NA	NA	NA
AYP79473.1\|51447_52053_+	DUF2913 family protein	NA	NA	NA	NA
AYP79474.1\|52049_52991_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.7e-74	54.7
AYP79475.1\|53405_54611_+	ParA family protein	A0A077SL49	Escherichia_phage	1.5e-162	69.3
AYP79476.1\|54607_55585_+	ParB/RepB/Spo0J family partition protein	A0A1B0V750	Salmonella_phage	6.7e-84	53.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP033340

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CRISPR-Cas detection and classification

Crispr_ID: CP033340_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033340_1

940761-941277

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAAC	CRT

8 spacers

cas3

The CRISPR arrays of CP033340_1

>merge|CP033340|1|940761-941277|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACTGAGGATTTCGCCGCGCTGTTGGCCTCCAGATTCGTGTTCCCCGCGCCAGCGGGGATAAACTGCCGTGCCTGTCCAGGACAAATTGCCGATTATTGTGTTCCCCGCGCCAGCGGGGATAAACTGCTGCCGGTCTGTGCTGTTGTCGTCAATAATCAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCATGTGACAGTCTGATTTTTATAGCGCATGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTGGGACATTCTCGCTAGTCACGGTCATGTCATGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGTCGCAGCCTGGCCTGTTGCCGTAGAATCGGTGTTCCCCTCGCCAGCGGGGATAAACCGAGTTACTGATGCAGACTGCGGATCTTAATCGGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCGCCAACGACTGGAATTTTTGCGTGTAGCCGTGTTCCCCGCGCCAACAAGGATAGCCGT

>CP033340|1|1|940761-941216|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACTG	AGGATTTCGCCGCGCTGTTGGCCTCCAGATTC
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CCGTGCCTGTCCAGGACAAATTGCCGATTATT
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CTGCCGGTCTGTGCTGTTGTCGTCAATAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATGTGACAGTCTGATTTTTATAGCGCATGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGGACATTCTCGCTAGTCACGGTCATGTCAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGTCGCAGCCTGGCCTGTTGCCGTAGAATCG
GTGTTCCCCTCGCCAGCGGGGATAAACCG	AGTTACTGATGCAGACTGCGGATCTTAATCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP033340|1|1|940761-941277|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACTG	AGGATTTCGCCGCGCTGTTGGCCTCCAGATTC
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CCGTGCCTGTCCAGGACAAATTGCCGATTATT
GTGTTCCCCGCGCCAGCGGGGATAAACTG	CTGCCGGTCTGTGCTGTTGTCGTCAATAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATGTGACAGTCTGATTTTTATAGCGCATGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGGACATTCTCGCTAGTCACGGTCATGTCAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGTCGCAGCCTGGCCTGTTGCCGTAGAATCG
GTGTTCCCCTCGCCAGCGGGGATAAACCG	AGTTACTGATGCAGACTGCGGATCTTAATCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCAACGACTGGAATTTTTGCGTGTAGCC
GTGTTCCCCGCGCCAACAAGGATAGCCGT

>CP033340|1|1|940761-941275|CRT
GTGTTCCCCGCGCCAGCGGGGATAAAC	TGAGGATTTCGCCGCGCTGTTGGCCTCCAGATTC
GTGTTCCCCGCGCCAGCGGGGATAAAC	TGCCGTGCCTGTCCAGGACAAATTGCCGATTATT
GTGTTCCCCGCGCCAGCGGGGATAAAC	TGCTGCCGGTCTGTGCTGTTGTCGTCAATAATCA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGGCATGTGACAGTCTGATTTTTATAGCGCATGA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGTGGGACATTCTCGCTAGTCACGGTCATGTCAT
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGCGGTCGCAGCCTGGCCTGTTGCCGTAGAATCG
GTGTTCCCCTCGCCAGCGGGGATAAAC	CGAGTTACTGATGCAGACTGCGGATCTTAATCGG
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGTGCGCCAACGACTGGAATTTTTGCGTGTAGCC
GTGTTCCCCGCGCCAACAAGGATAGCC

Protein	Signature genes	Signature genes Name	Protein_function
CP033340.1\|AYP79185.1\|947481_948435_-\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
CP033340.1\|AYP79186.1\|948550_948757_-\|hypothetical-protein	unknown	unknown	unknown
CP033340.1\|AYP79183.1\|942551_942722_+\|6-pyruvoyl-tetrahydrobiopterin-synthase	unknown	unknown	unknown
CP033340.1\|AYP75771.1\|946659_947394_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP033340.1\|AYP75760.1\|930850_931624_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185177
CP033340.1\|AYP75767.1\|941375_942173_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
CP033340.1\|AYP79184.1\|946514_946733_-\|hypothetical-protein	unknown	unknown	unknown
CP033340.1\|AYP75758.1\|929839_930310_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
CP033340.1\|AYP75772.1\|948878_951542_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP033340.1\|AYP75770.1\|944845_946558_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
CP033340.1\|AYP75769.1\|943046_944846_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
CP033340.1\|AYP75761.1\|931636_934336_-\|PapC/FimD-family-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
CP033340.1\|AYP75764.1\|936638_938276_+\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
CP033340.1\|AYP75763.1\|935610_936411_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
CP033340.1\|AYP75768.1\|942260_942623_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP033340.1\|AYP75762.1\|934415_935003_-\|fimbrial-protein-SteA	unknown	unknown	gnl\|CDD\|185169
CP033340.1\|AYP75765.1\|938358_939657_+\|enolase	unknown	unknown	gnl\|CDD\|234617
CP033340.1\|AYP75757.1\|929306_929843_-\|fimbrial-protein-SteF	unknown	unknown	gnl\|CDD\|185168
CP033340.1\|AYP75766.1\|939792_940464_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
CP033340.1\|AYP75759.1\|930324_930831_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178

Protein	Function_ID	Function_description	E-value
CP033340.1\|AYP79185.1\|947481_948435_-\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
CP033340.1\|AYP75771.1\|946659_947394_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
CP033340.1\|AYP75760.1\|930850_931624_-\|fimbrial-protein	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
CP033340.1\|AYP75767.1\|941375_942173_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.00381e-102
CP033340.1\|AYP75758.1\|929839_930310_-\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	2.10162e-98
CP033340.1\|AYP75772.1\|948878_951542_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
CP033340.1\|AYP75770.1\|944845_946558_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP033340.1\|AYP75769.1\|943046_944846_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP033340.1\|AYP75761.1\|931636_934336_-\|PapC/FimD-family-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
CP033340.1\|AYP75764.1\|936638_938276_+\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP033340.1\|AYP75763.1\|935610_936411_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
CP033340.1\|AYP75768.1\|942260_942623_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
CP033340.1\|AYP75762.1\|934415_935003_-\|fimbrial-protein-SteA	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.36845e-100
CP033340.1\|AYP75765.1\|938358_939657_+\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP033340.1\|AYP75757.1\|929306_929843_-\|fimbrial-protein-SteF	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	7.785e-121
CP033340.1\|AYP75766.1\|939792_940464_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
CP033340.1\|AYP75759.1\|930324_930831_-\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	4.31975e-105

>CP033340.1|AYP75766.1|939792_940464_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>CP033340.1|AYP75765.1|938358_939657_+|enolase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP033340.1|AYP75764.1|936638_938276_+|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>CP033340.1|AYP75763.1|935610_936411_+|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>CP033340.1|AYP75762.1|934415_935003_-|fimbrial-protein-SteA
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>CP033340.1|AYP75761.1|931636_934336_-|PapC/FimD-family-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSLSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVVSDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWLAGVKAGETLKVFWDGAAQCEASLPSTFTPELLANALLLPCKMLEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>CP033340.1|AYP75760.1|930850_931624_-|fimbrial-protein
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>CP033340.1|AYP75759.1|930324_930831_-|fimbrial-protein
MTMLTRWKMLVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTVGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>CP033340.1|AYP75758.1|929839_930310_-|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGEMLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTSVPELGIELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>CP033340.1|AYP75757.1|929306_929843_-|fimbrial-protein-SteF
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ
>CP033340.1|AYP75767.1|941375_942173_+|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGKNFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>CP033340.1|AYP75768.1|942260_942623_-|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>CP033340.1|AYP79183.1|942551_942722_+|6-pyruvoyl-tetrahydrobiopterin-synthase
MPFRHVRQAVSGFKGEIFIQRGGHDELSGNKKTAVGYRKAHFLSLTKTILRLVTGN
>CP033340.1|AYP75769.1|943046_944846_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGVVAVTPVPERKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWCWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>CP033340.1|AYP75770.1|944845_946558_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>CP033340.1|AYP79184.1|946514_946733_-|hypothetical-protein
MVSANASTRSTFGSSFRAFRSSLDISSSRYTLPDGASLIRPTRAVGRIRHLCRHPAIQVIPRNHARDRAPGE
>CP033340.1|AYP75771.1|946659_947394_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP033340.1|AYP79185.1|947481_948435_-|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>CP033340.1|AYP79186.1|948550_948757_-|hypothetical-protein
MFFRNIYPTNNYYKFFRLFLLEEALKEASSNAFCINQNLKKTTICGESSTFCLNYRHHKGLPTINVLY
>CP033340.1|AYP75772.1|948878_951542_+|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE

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Crispr_ID: CP033340_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033340_2

957429-958006

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

9 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of CP033340_2

>merge|CP033340|2|957429-958006|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGACGTTGGCTGAAAACGGTTTTTCGGTCCGCCTGTGTTCCCCGCGCCAGCGGGGATAAACCGAGAGCGAGCACGTCCGCCGTAAAATTGCCATGGTGTTCCCCGCGCCAGCGGGGATAAACCGAATATATGGCGCTCACGCGCATGAGCATTCTCGTGTTCCCCGCGCCAGCGGGGATAAACCGCAGGGCAAATTCATCCGCCGCTGACCACTGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGACGCTTACATCTCACCGAGAGATTTTGAGGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGGAACTGGTTTAGCTATCGCTGCCGGGGCTATGTGTTCCCCGCGCCAGCGGGGATAAACCGGATTGCTCAGATTGGGAATTTGACCAGCGGCCGTGTTCCCCGCGCCAGCGGGGATAAACCGTCACGAGGGCCCCCTTATTGGGTCGGGCAGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGTTGGGTTGCATAGATGACACGCTTATAAATAGTGTTCCCCGCGTCAGCGGGGATAAACAC

>CP033340|2|2|957429-957945|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGTTGGCTGAAAACGGTTTTTCGGTCCGCCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGAGCGAGCACGTCCGCCGTAAAATTGCCATG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATATATGGCGCTCACGCGCATGAGCATTCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGGCAAATTCATCCGCCGCTGACCACTGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCTTACATCTCACCGAGAGATTTTGAGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAACTGGTTTAGCTATCGCTGCCGGGGCTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATTGCTCAGATTGGGAATTTGACCAGCGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACGAGGGCCCCCTTATTGGGTCGGGCAGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP033340|2|2|957429-958006|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGTTGGCTGAAAACGGTTTTTCGGTCCGCCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGAGCGAGCACGTCCGCCGTAAAATTGCCATG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATATATGGCGCTCACGCGCATGAGCATTCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGGCAAATTCATCCGCCGCTGACCACTGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCTTACATCTCACCGAGAGATTTTGAGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAACTGGTTTAGCTATCGCTGCCGGGGCTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATTGCTCAGATTGGGAATTTGACCAGCGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACGAGGGCCCCCTTATTGGGTCGGGCAGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTGGGTTGCATAGATGACACGCTTATAAATA
GTGTTCCCCGCGTCAGCGGGGATAAACAC

>CP033340|2|2|957429-958006|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGTTGGCTGAAAACGGTTTTTCGGTCCGCCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGAGCGAGCACGTCCGCCGTAAAATTGCCATG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATATATGGCGCTCACGCGCATGAGCATTCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGGCAAATTCATCCGCCGCTGACCACTGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCTTACATCTCACCGAGAGATTTTGAGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAACTGGTTTAGCTATCGCTGCCGGGGCTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GATTGCTCAGATTGGGAATTTGACCAGCGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACGAGGGCCCCCTTATTGGGTCGGGCAGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTGGGTTGCATAGATGACACGCTTATAAATA
GTGTTCCCCGCGTCAGCGGGGATAAACAC

Protein	Signature genes	Signature genes Name	Protein_function
CP033340.1\|AYP75781.1\|959317_960226_+\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP033340.1\|AYP75774.1\|953106_953661_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP033340.1\|AYP79185.1\|947481_948435_-\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
CP033340.1\|AYP79186.1\|948550_948757_-\|hypothetical-protein	unknown	unknown	unknown
CP033340.1\|AYP75789.1\|965377_966139_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP033340.1\|AYP75773.1\|951553_953110_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
CP033340.1\|AYP75782.1\|960235_961675_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235349
CP033340.1\|AYP75772.1\|948878_951542_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP033340.1\|AYP75787.1\|963871_964351_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP033340.1\|AYP75777.1\|955471_956122_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
CP033340.1\|AYP75775.1\|953674_954733_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
CP033340.1\|AYP75779.1\|957038_957332_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP033340.1\|AYP75785.1\|962831_963143_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP033340.1\|AYP75778.1\|956118_957039_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP033340.1\|AYP75780.1\|958020_959067_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
CP033340.1\|AYP75783.1\|961661_962267_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP033340.1\|AYP75784.1\|962284_962641_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
CP033340.1\|AYP75788.1\|964347_965397_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP033340.1\|AYP75786.1\|963161_963872_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP033340.1\|AYP75776.1\|954743_955490_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776

Protein	Function_ID	Function_description	E-value
CP033340.1\|AYP75781.1\|959317_960226_+\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP033340.1\|AYP75774.1\|953106_953661_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
CP033340.1\|AYP79185.1\|947481_948435_-\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
CP033340.1\|AYP75786.1\|963161_963872_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.09575e-119
CP033340.1\|AYP75789.1\|965377_966139_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
CP033340.1\|AYP75773.1\|951553_953110_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
CP033340.1\|AYP75782.1\|960235_961675_+\|sulfate-adenylyltransferase	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP033340.1\|AYP75772.1\|948878_951542_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
CP033340.1\|AYP75787.1\|963871_964351_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.84083e-103
CP033340.1\|AYP75777.1\|955471_956122_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.7595e-75
CP033340.1\|AYP75775.1\|953674_954733_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
CP033340.1\|AYP75779.1\|957038_957332_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62
CP033340.1\|AYP75785.1\|962831_963143_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
CP033340.1\|AYP75778.1\|956118_957039_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.63116e-157
CP033340.1\|AYP75780.1\|958020_959067_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP033340.1\|AYP75783.1\|961661_962267_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	2.19317e-145
CP033340.1\|AYP75784.1\|962284_962641_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	4.85353e-49
CP033340.1\|AYP75788.1\|964347_965397_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP033340.1\|AYP75776.1\|954743_955490_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.23137e-48

>CP033340.1|AYP75779.1|957038_957332_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>CP033340.1|AYP75778.1|956118_957039_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>CP033340.1|AYP75777.1|955471_956122_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASTIFDVQTRPFAPMLSAGQTLRFNLRANPTICKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALEWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVINEPALFLQRLAQGYGKSRAFGCGMMMIKPGDDA
>CP033340.1|AYP75776.1|954743_955490_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNTFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGNAADVLREAYRWYQDQFNALKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>CP033340.1|AYP75775.1|953674_954733_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA
>CP033340.1|AYP75774.1|953106_953661_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>CP033340.1|AYP75773.1|951553_953110_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>CP033340.1|AYP75772.1|948878_951542_+|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>CP033340.1|AYP79186.1|948550_948757_-|hypothetical-protein
MFFRNIYPTNNYYKFFRLFLLEEALKEASSNAFCINQNLKKTTICGESSTFCLNYRHHKGLPTINVLY
>CP033340.1|AYP79185.1|947481_948435_-|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>CP033340.1|AYP75780.1|958020_959067_-|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>CP033340.1|AYP75781.1|959317_960226_+|sulfate-adenylyltransferase-subunit-2
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>CP033340.1|AYP75782.1|960235_961675_+|sulfate-adenylyltransferase
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYCEETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>CP033340.1|AYP75783.1|961661_962267_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHCGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>CP033340.1|AYP75784.1|962284_962641_+|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>CP033340.1|AYP75785.1|962831_963143_+|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>CP033340.1|AYP75786.1|963161_963872_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>CP033340.1|AYP75787.1|963871_964351_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>CP033340.1|AYP75788.1|964347_965397_+|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>CP033340.1|AYP75789.1|965377_966139_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP033340_1	1.3\|940912\|32\|CP033340\|PILER-CR,CRISPRCasFinder	940912-940943	32	MG592432	Vibrio phage 1.050.O._10N.286.48.A6, partial genome	21687-21718	8	0.75
CP033340_1	1.3\|940912\|32\|CP033340\|PILER-CR,CRISPRCasFinder	940912-940943	32	MG592431	Vibrio phage 1.049.O._10N.286.54.B5, partial genome	21426-21457	8	0.75
CP033340_1	1.6\|941095\|32\|CP033340\|PILER-CR,CRISPRCasFinder	941095-941126	32	MN694003	Marine virus AFVG_250M677, complete genome	17629-17660	8	0.75
CP033340_1	1.14\|941093\|34\|CP033340\|CRT	941093-941126	34	MN694003	Marine virus AFVG_250M677, complete genome	17627-17660	8	0.765
CP033340_1	1.1\|940790\|32\|CP033340\|PILER-CR,CRISPRCasFinder	940790-940821	32	CP006879	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence	405613-405644	9	0.719
CP033340_1	1.3\|940912\|32\|CP033340\|PILER-CR,CRISPRCasFinder	940912-940943	32	NC_047790	Pseudoalteromonas phage C5a, complete genome	34441-34472	9	0.719
CP033340_2	2.3\|957580\|32\|CP033340\|PILER-CR,CRISPRCasFinder,CRT	957580-957611	32	KY006853	Erythrobacter phage vB_EliS_R6L, complete genome	41418-41449	9	0.719
CP033340_2	2.7\|957824\|32\|CP033340\|PILER-CR,CRISPRCasFinder,CRT	957824-957855	32	MK449011	Streptococcus phage Javan92, complete genome	36157-36188	9	0.719
CP033340_2	2.7\|957824\|32\|CP033340\|PILER-CR,CRISPRCasFinder,CRT	957824-957855	32	MK448835	Streptococcus phage Javan93, complete genome	36157-36188	9	0.719
CP033340_2	2.7\|957824\|32\|CP033340\|PILER-CR,CRISPRCasFinder,CRT	957824-957855	32	MK448836	Streptococcus phage Javan95, complete genome	37400-37431	9	0.719
CP033340_2	2.7\|957824\|32\|CP033340\|PILER-CR,CRISPRCasFinder,CRT	957824-957855	32	MK448825	Streptococcus phage Javan639, complete genome	37400-37431	9	0.719
CP033340_2	2.9\|957946\|32\|CP033340\|CRISPRCasFinder,CRT	957946-957977	32	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	5501-5532	9	0.719
CP033340_1	1.1\|940790\|32\|CP033340\|PILER-CR,CRISPRCasFinder	940790-940821	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	699963-699994	10	0.688

1. spacer 1.3|940912|32|CP033340|PILER-CR,CRISPRCasFinder matches to MG592432 (Vibrio phage 1.050.O._10N.286.48.A6, partial genome) position: , mismatch: 8, identity: 0.75

ctgccggtctgtgctgttgtcgtcaataatca	CRISPR spacer
aatctgctctgtgctgttgtagtcaattataa	Protospacer
   *.* ************* ****** ** *

2. spacer 1.3|940912|32|CP033340|PILER-CR,CRISPRCasFinder matches to MG592431 (Vibrio phage 1.049.O._10N.286.54.B5, partial genome) position: , mismatch: 8, identity: 0.75

ctgccggtctgtgctgttgtcgtcaataatca	CRISPR spacer
aatctgctctgtgctgttgtagtcaattataa	Protospacer
   *.* ************* ****** ** *

3. spacer 1.6|941095|32|CP033340|PILER-CR,CRISPRCasFinder matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.75

cggtcgcagcctggcctgttgccgtagaatcg	CRISPR spacer
cgatcgcagcctgggctgttgccgtgctcgcc	Protospacer
**.*********** **********.    *

4. spacer 1.14|941093|34|CP033340|CRT matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.765

cgcggtcgcagcctggcctgttgccgtagaatcg	CRISPR spacer
cgcgatcgcagcctgggctgttgccgtgctcgcc	Protospacer
****.*********** **********.    *

5. spacer 1.1|940790|32|CP033340|PILER-CR,CRISPRCasFinder matches to CP006879 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence) position: , mismatch: 9, identity: 0.719

aggatttcgccgcgctgttggcctccagattc	CRISPR spacer
cagggtcgaccgcgctgtcgccctccagattc	Protospacer
 .*. *. .*********.* ***********

6. spacer 1.3|940912|32|CP033340|PILER-CR,CRISPRCasFinder matches to NC_047790 (Pseudoalteromonas phage C5a, complete genome) position: , mismatch: 9, identity: 0.719

ctgccggtctgtgctgttgtcgtcaataatca	CRISPR spacer
tttggtgtctgtgccgttttcgtcaataagct	Protospacer
.*    ********.*** ********** *

7. spacer 2.3|957580|32|CP033340|PILER-CR,CRISPRCasFinder,CRT matches to KY006853 (Erythrobacter phage vB_EliS_R6L, complete genome) position: , mismatch: 9, identity: 0.719

aatatatggcgctcacgcgcatgagcattctc	CRISPR spacer
acgcaatggcgctgacgcgcatgatcatttcg	Protospacer
*    ******** ********** ****..

8. spacer 2.7|957824|32|CP033340|PILER-CR,CRISPRCasFinder,CRT matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

9. spacer 2.7|957824|32|CP033340|PILER-CR,CRISPRCasFinder,CRT matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

10. spacer 2.7|957824|32|CP033340|PILER-CR,CRISPRCasFinder,CRT matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

11. spacer 2.7|957824|32|CP033340|PILER-CR,CRISPRCasFinder,CRT matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 9, identity: 0.719

gattgctcagattgggaatttgaccagcggcc	CRISPR spacer
agtcgctcagattgggaatttgtcaagatgta	Protospacer
..*.****************** * **  *.

12. spacer 2.9|957946|32|CP033340|CRISPRCasFinder,CRT matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 9, identity: 0.719

gttgggttgcatagatgacacgcttataaata	CRISPR spacer
gaattatggcatagatgacatgattataaatt	Protospacer
*    .* ************.* ********

13. spacer 1.1|940790|32|CP033340|PILER-CR,CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

aggatttcgccgcgctgttggcctccagattc	CRISPR spacer
gggatatcgccgcgctgatggcctatgaccac	Protospacer
.**** *********** ****** ... . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1414589 : 1420649

Salmonella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP76176.1\|1414589_1414841_+	hypothetical protein	A0A1R3Y5S2	Salmonella_virus	7.6e-08	68.6
AYP76177.1\|1414779_1414923_+	hypothetical protein	A0A1R3Y5S2	Salmonella_virus	1.7e-12	82.9
AYP76178.1\|1415912_1417835_-	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	5.6e-300	77.3
AYP76179.1\|1417852_1418107_-	glycosyltransferase	A8CG95	Salmonella_phage	3.1e-25	79.5
AYP79202.1\|1418075_1418465_-	GtrA family protein	A0A192Y6N5	Salmonella_phage	1.1e-50	85.6
AYP76180.1\|1419707_1420649_-	hypothetical protein	E7DYY8	Enterobacteria_phage	1.6e-146	87.8

DBSCAN-SWA_2

1657080 : 1666251

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP76400.1\|1657080_1658028_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.8e-10	27.8
AYP76401.1\|1658011_1658743_+	ABC transporter permease	NA	NA	NA	NA
AYP76402.1\|1658723_1658831_-	protein YohO	NA	NA	NA	NA
AYP76403.1\|1658890_1659622_-	transcriptional regulator	Q9EYF2	Enterobacteria_phage	1.7e-100	87.4
AYP76404.1\|1659844_1661530_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	6.2e-279	91.1
AYP76405.1\|1661526_1662246_+	DNA-binding response regulator	NA	NA	NA	NA
AYP76406.1\|1662292_1662760_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	4.3e-73	89.7
AYP76407.1\|1662816_1663347_-	DUF1307 domain-containing protein	NA	NA	NA	NA
AYP76408.1\|1663518_1663977_-	DUF1307 domain-containing protein	Q9EYF5	Enterobacteria_phage	6.4e-53	72.5
AYP76409.1\|1664217_1666251_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	6.1e-55	26.9

DBSCAN-SWA_3

1733448 : 1743955

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP76464.1\|1733448_1734852_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	3.1e-21	26.5
AYP76465.1\|1735029_1735923_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	4.8e-44	42.2
AYP76466.1\|1736299_1737385_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-102	53.9
AYP76467.1\|1737384_1738284_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
AYP79211.1\|1738331_1739210_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.1e-108	65.5
AYP76468.1\|1739210_1739762_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-52	58.0
AYP76469.1\|1739767_1740742_+	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
AYP76470.1\|1740757_1741531_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
AYP76471.1\|1741535_1742615_+	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.7e-16	24.5
AYP76472.1\|1742641_1743955_+	LPS biosynthesis protein	H8ZJ36	Ostreococcus_tauri_virus	7.0e-52	35.1

DBSCAN-SWA_4

1858685 : 1869655

Salmonella_phage(54.55%)

lysis,integrase,terminase

attL 1856579:1856592|attR 1865590:1865603

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1856579:1856592	attL	NA	NA	NA	NA
AYP76582.1\|1858685_1860587_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	3.0e-136	43.1
AYP76583.1\|1860738_1862037_-	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	6.2e-69	38.2
AYP76584.1\|1862701_1862992_-	DUF4102 domain-containing protein	H2BDA3	Pseudomonas_phage	1.2e-07	49.1
AYP76585.1\|1863363_1864161_-	protein MtfA	NA	NA	NA	NA
AYP76586.1\|1864452_1865442_-\|integrase	integrase	A0A192Y7M7	Salmonella_phage	8.6e-196	100.0
AYP76587.1\|1865443_1865686_-	DUF4224 domain-containing protein	Q8HAA9	Salmonella_phage	9.5e-40	100.0
1865590:1865603	attR	NA	NA	NA	NA
AYP76588.1\|1865710_1866280_-	3'-5' exoribonuclease	A0A192Y6E0	Salmonella_phage	7.1e-110	100.0
AYP76589.1\|1866283_1867117_-	hypothetical protein	Q8HAA7	Salmonella_phage	4.0e-162	99.6
AYP76590.1\|1867127_1867385_-	hypothetical protein	A0A192Y5W0	Salmonella_phage	4.9e-42	98.8
AYP76591.1\|1867435_1867810_+\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	8.9e-53	91.7
AYP76592.1\|1868294_1868618_-	hypothetical protein	NA	NA	NA	NA
AYP76593.1\|1868668_1869058_+	HNH endonuclease	K7P6U5	Enterobacteria_phage	1.4e-45	72.1
AYP76594.1\|1869190_1869655_+\|terminase	phage terminase small subunit P27 family	Q9B019	Phage_GMSE-1	1.3e-48	62.1

DBSCAN-SWA_5

1979822 : 1989808

Salmonella_phage(50.0%)

capsid,integrase

attL 1981139:1981152|attR 1994045:1994058

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP76706.1\|1979822_1981073_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.1e-19	90.7
1981139:1981152	attL	NA	NA	NA	NA
AYP76707.1\|1981186_1982329_-\|integrase	integrase	O21929	Phage_21	4.5e-172	79.7
AYP76708.1\|1982318_1982555_-	excisionase	NA	NA	NA	NA
AYP79224.1\|1982604_1983102_-	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	5.6e-18	67.6
AYP76709.1\|1983433_1983973_-	HD family hydrolase	A0A192Y8M4	Salmonella_phage	2.6e-98	100.0
AYP76710.1\|1984067_1984985_-	recombination-associated protein RdgC	S4TWL4	Salmonella_phage	4.2e-96	59.1
AYP76711.1\|1985272_1985503_+	hypothetical protein	NA	NA	NA	NA
AYP76712.1\|1985676_1985991_+	antitermination protein	A0A192Y5X6	Salmonella_phage	4.8e-52	96.9
AYP76713.1\|1986040_1987114_+	hypothetical protein	NA	NA	NA	NA
AYP76714.1\|1987126_1987699_+	hypothetical protein	NA	NA	NA	NA
AYP76715.1\|1987787_1988177_+	hypothetical protein	K7PHB9	Enterobacterial_phage	8.1e-41	71.8
AYP76716.1\|1988284_1989808_+\|capsid	phage major capsid protein	A0A192Y5U9	Salmonella_phage	2.5e-234	97.7
1994045:1994058	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2429403 : 2440190

Escherichia_phage(72.73%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP77140.1\|2429403_2429940_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.4e-70	70.9
AYP77141.1\|2429936_2430227_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	5.1e-40	76.0
AYP77142.1\|2430226_2430826_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	5.5e-97	82.9
AYP77143.1\|2431349_2431562_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	2.5e-28	95.7
AYP77144.1\|2431931_2432864_+	hypothetical protein	NA	NA	NA	NA
AYP77145.1\|2432860_2433415_+	hypothetical protein	NA	NA	NA	NA
AYP77146.1\|2433576_2433906_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	6.5e-23	51.7
AYP77147.1\|2434178_2434646_+	helix-turn-helix domain-containing protein	A0A0U2QW76	Escherichia_phage	1.0e-53	66.9
AYP79239.1\|2435030_2435186_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	2.6e-06	48.9
AYP77148.1\|2435293_2435815_-	hypothetical protein	NA	NA	NA	NA
AYP77149.1\|2436252_2436474_+	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	7.9e-33	83.6
AYP77150.1\|2436558_2436876_+	hypothetical protein	NA	NA	NA	NA
AYP77151.1\|2436903_2437521_+	exodeoxyribonuclease	A0A088CD28	Shigella_phage	2.5e-36	41.9
AYP77152.1\|2437837_2438773_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	7.2e-144	97.3
AYP77153.1\|2438816_2440190_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.1e-51	32.0

DBSCAN-SWA_7

2609193 : 2679311

Enterobacteria_phage(25.0%)

tRNA,tail,integrase,protease,holin,lysis

attL 2659826:2659855|attR 2679447:2679476

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP77318.1\|2609193_2609889_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
AYP77319.1\|2609946_2611857_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	4.5e-92	32.7
AYP77320.1\|2611987_2612332_+	RidA family protein	NA	NA	NA	NA
AYP77321.1\|2612337_2612517_-	YoaH family protein	NA	NA	NA	NA
AYP77322.1\|2612597_2613962_+	aminodeoxychorismate synthase component 1	A0A0B5J984	Pandoravirus	3.6e-43	34.5
AYP77323.1\|2613965_2614544_+	coenzyme A pyrophosphatase	NA	NA	NA	NA
AYP77324.1\|2614807_2616172_+	L-serine ammonia-lyase	NA	NA	NA	NA
AYP77325.1\|2616309_2617911_+	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
AYP77326.1\|2617932_2619492_-	TerC family protein	A0A0R6PEZ3	Moraxella_phage	9.5e-40	44.4
AYP77327.1\|2619479_2619815_-	hypothetical protein	NA	NA	NA	NA
AYP77328.1\|2619964_2620933_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
AYP77329.1\|2620985_2621786_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
AYP77330.1\|2621798_2622650_+	PTS mannose transporter subunit IID	NA	NA	NA	NA
AYP77331.1\|2622708_2623167_+	DUF986 domain-containing protein	NA	NA	NA	NA
AYP79249.1\|2623522_2624143_+	manganese efflux pump MntP	NA	NA	NA	NA
AYP77332.1\|2624139_2624949_-	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
AYP77333.1\|2625014_2626760_-	peptidoglycan glycosyltransferase FtsI	NA	NA	NA	NA
AYP77334.1\|2626979_2627189_-	cold-shock protein CspC	A0A1W6JNX5	Morganella_phage	1.6e-22	78.1
AYP77335.1\|2627201_2627345_-	DUF2627 domain-containing protein	NA	NA	NA	NA
AYP77336.1\|2627993_2628281_-	hypothetical protein	NA	NA	NA	NA
AYP77337.1\|2628351_2628495_-	PhoP/PhoQ regulator MgrB	NA	NA	NA	NA
AYP77338.1\|2628652_2628892_+	hypothetical protein	NA	NA	NA	NA
AYP77339.1\|2629103_2629895_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
AYP77340.1\|2630070_2631444_+	MFS transporter	NA	NA	NA	NA
AYP77341.1\|2631491_2632373_-\|protease	protease HtpX	NA	NA	NA	NA
AYP77342.1\|2632567_2634616_-\|tail,protease	tail-specific protease	A0A0R6PIZ1	Moraxella_phage	8.0e-87	33.5
AYP77343.1\|2634635_2635322_-	RNA chaperone ProQ	NA	NA	NA	NA
AYP77344.1\|2635419_2636004_-	GAF domain-containing protein	NA	NA	NA	NA
AYP77345.1\|2636045_2637329_+	paraquat-inducible protein A	NA	NA	NA	NA
AYP77346.1\|2637291_2639931_+	PqiB family protein	NA	NA	NA	NA
AYP79250.1\|2640008_2641448_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
AYP77347.1\|2641562_2641802_+	DUF1480 family protein	NA	NA	NA	NA
AYP77348.1\|2641912_2642104_+	DUF1482 family protein	NA	NA	NA	NA
AYP77349.1\|2642122_2642773_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	7.2e-58	50.9
AYP77350.1\|2642996_2643161_-	hypothetical protein	NA	NA	NA	NA
AYP77351.1\|2643445_2644168_-	SPI-1 type III secretion system guanine nucleotide exchange factor SopE2	NA	NA	NA	NA
AYP77352.1\|2644851_2645247_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	9.2e-16	32.8
AYP77353.1\|2645576_2646053_+	hypothetical protein	NA	NA	NA	NA
AYP77354.1\|2646425_2646845_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYP77355.1\|2646976_2647171_-	hypothetical protein	NA	NA	NA	NA
AYP77356.1\|2647217_2647487_+	hypothetical protein	B6SCX2	Bacteriophage	3.1e-07	47.9
AYP77357.1\|2647652_2647793_+	hypothetical protein	NA	NA	NA	NA
AYP79251.1\|2650113_2650314_-	hypothetical protein	NA	NA	NA	NA
AYP77358.1\|2650931_2651846_+	protein PagO	NA	NA	NA	NA
AYP77359.1\|2651978_2652137_+	hypothetical protein	NA	NA	NA	NA
AYP77360.1\|2652146_2652761_+	disulfide bond formation protein B	NA	NA	NA	NA
AYP77361.1\|2653895_2654021_-	arsenic transporter	NA	NA	NA	NA
AYP77362.1\|2654283_2654400_+\|tail	phage tail protein	NA	NA	NA	NA
AYP77363.1\|2654590_2654791_+	phage virulence factor	NA	NA	NA	NA
AYP77364.1\|2657492_2657984_-	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	7.1e-42	56.2
AYP77365.1\|2658038_2658227_+	hypothetical protein	NA	NA	NA	NA
AYP77366.1\|2658291_2658459_+	lytic enzyme	NA	NA	NA	NA
AYP77367.1\|2658715_2659249_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	5.4e-11	43.0
AYP79252.1\|2659315_2659699_+\|integrase	integrase	K7PHK0	Enterobacteria_phage	2.7e-12	37.4
2659826:2659855	attL	NA	NA	NA	NA
AYP77368.1\|2660643_2661444_+	hypothetical protein	NA	NA	NA	NA
AYP77369.1\|2661923_2662646_+	guanine nucleotide exchange factor SopE	NA	NA	NA	NA
AYP77370.1\|2663196_2664060_-	DUF1983 domain-containing protein	K7PKJ2	Enterobacteria_phage	9.0e-48	78.9
AYP77371.1\|2666700_2667396_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.0e-89	66.7
AYP77372.1\|2667485_2668019_+	superoxide dismutase [Cu-Zn] SodC1	Q9MC02	Salmonella_phage	1.8e-46	54.0
AYP79254.1\|2668913_2669393_-\|lysis	lysis protein	Q56118	Enterobacteria_phage	1.4e-55	77.0
AYP77373.1\|2669410_2669863_-	lysozyme	A0A0M4R365	Salmonella_phage	2.3e-79	97.3
AYP79253.1\|2669846_2670176_-\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
AYP77374.1\|2670451_2671138_+\|protease	type III secretion system effector protease GtgA	Q9MBM0	Phage_Gifsy-2	1.8e-131	99.6
AYP77375.1\|2671498_2671948_+	hypothetical protein	NA	NA	NA	NA
AYP79255.1\|2672321_2672846_-	hypothetical protein	NA	NA	NA	NA
AYP77376.1\|2672942_2673632_-	antiterminator	I6PDF8	Cronobacter_phage	2.1e-60	54.9
AYP77377.1\|2673761_2673989_-	DNA breaking-rejoining protein	A0A0M4RU10	Salmonella_phage	2.2e-14	66.7
AYP77378.1\|2673985_2674585_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	4.7e-96	82.9
AYP77379.1\|2674648_2674954_-	hypothetical protein	NA	NA	NA	NA
AYP77380.1\|2675376_2675568_+	hypothetical protein	NA	NA	NA	NA
AYP77381.1\|2675585_2677565_-	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	1.9e-162	46.3
AYP77382.1\|2677978_2678257_+	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.4e-10	37.5
AYP77383.1\|2678231_2679311_+\|integrase	integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	3.0e-101	52.5
2679447:2679476	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2851702 : 2892400

Salmonella_phage(28.57%)

protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYP77565.1\|2851702_2852383_+\|protease	type III secretion system effector protease PipA	Q9MBM0	Phage_Gifsy-2	2.2e-81	71.0
AYP77566.1\|2853001_2853661_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4
AYP77567.1\|2853747_2854077_+	sulfurtransferase TusE	NA	NA	NA	NA
AYP77568.1\|2854073_2854355_-	acylphosphatase	NA	NA	NA	NA
AYP77569.1\|2854403_2855183_-	AraC family transcriptional regulator	NA	NA	NA	NA
AYP77570.1\|2855208_2855757_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AYP77571.1\|2855971_2857183_+	ribosomal RNA large subunit methyltransferase I	NA	NA	NA	NA
AYP77572.1\|2857240_2857558_+	heat-shock protein HspQ	NA	NA	NA	NA
AYP77573.1\|2857602_2858019_-	CoA-binding protein	NA	NA	NA	NA
AYP77574.1\|2858189_2858852_+	DUF2057 family protein	NA	NA	NA	NA
AYP77575.1\|2858946_2859405_+	methylglyoxal synthase	NA	NA	NA	NA
AYP77576.1\|2859440_2861495_-	DNA helicase IV	A7KV33	Bacillus_phage	8.5e-20	27.6
AYP77577.1\|2861618_2862065_+	YccF domain-containing protein	NA	NA	NA	NA
AYP77578.1\|2862083_2864237_+	TIGR01666 family membrane protein	NA	NA	NA	NA
AYP77579.1\|2864223_2864829_-	DNA transformation protein	NA	NA	NA	NA
AYP77580.1\|2865045_2865555_+	cell division inhibitor SulA	NA	NA	NA	NA
AYP79265.1\|2865911_2866964_+	outer membrane protein A	NA	NA	NA	NA
AYP77581.1\|2867035_2867488_-	macrodomain Ter protein	NA	NA	NA	NA
AYP77582.1\|2867673_2869434_+\|protease	Lon protease family protein	NA	NA	NA	NA
AYP77583.1\|2869502_2870021_+	beta-hydroxydecanoyl-ACP dehydratase	NA	NA	NA	NA
AYP77584.1\|2870120_2870288_-	ribosome modulation factor	NA	NA	NA	NA
AYP77585.1\|2870543_2871107_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
AYP77586.1\|2871103_2872744_-	intermembrane transport protein PqiB	NA	NA	NA	NA
AYP77587.1\|2872748_2874002_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
AYP77588.1\|2874016_2875924_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.4e-53	29.8
AYP77589.1\|2875936_2878045_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
AYP77590.1\|2878143_2879253_+	MOSC domain-containing protein	NA	NA	NA	NA
AYP77591.1\|2879249_2879792_-	cell division protein ZapC	NA	NA	NA	NA
AYP77592.1\|2879957_2880968_-	dihydroorotate dehydrogenase (quinone)	NA	NA	NA	NA
AYP77593.1\|2881175_2883788_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	6.3e-20	22.8
AYP77594.1\|2884214_2884406_+	DinI family protein	S4TNM0	Salmonella_phage	6.2e-26	95.2
AYP77595.1\|2884676_2885363_+	virulence protein	NA	NA	NA	NA
AYP77596.1\|2885722_2886349_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	1.4e-66	63.2
AYP77597.1\|2886996_2887965_-	SPI-2 type III secretion system effector SseI	Q9MBL9	Phage_Gifsy-2	3.0e-193	99.4
AYP77598.1\|2888190_2888439_+\|tail	phage tail protein	A0A1B0VCD0	Salmonella_phage	2.8e-18	66.2
AYP77599.1\|2888442_2889024_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.7e-95	89.5
AYP77600.1\|2889023_2890733_-\|tail	tail fiber protein	A0A0U2SAV1	Escherichia_phage	1.5e-91	66.0
AYP77601.1\|2890729_2891356_-	hypothetical protein	A0A0U2RK03	Escherichia_phage	3.3e-92	71.6
AYP77602.1\|2891339_2891969_-	hypothetical protein	A0A0U2RJZ0	Escherichia_phage	1.6e-75	65.9
AYP77603.1\|2891989_2892400_+	enterohemolysin	H6WRX0	Salmonella_phage	5.0e-33	100.0

DBSCAN-SWA_9

2963718 : 2971031

Ralstonia_phage(16.67%)

protease,integrase

attL 2958515:2958529|attR 2969767:2969781

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2958515:2958529	attL	NA	NA	NA	NA
AYP77656.1\|2963718_2964096_+\|integrase	integrase	A0A077KET4	Ralstonia_phage	1.2e-20	41.0
AYP77657.1\|2964257_2964455_+	hypothetical protein	NA	NA	NA	NA
AYP77658.1\|2964667_2966944_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
AYP77659.1\|2966974_2967295_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
AYP77660.1\|2967618_2967840_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
AYP77661.1\|2967794_2967989_-	hypothetical protein	NA	NA	NA	NA
AYP77662.1\|2967969_2969916_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.0e-39	43.1
2969767:2969781	attR	NA	NA	NA	NA
AYP77663.1\|2969912_2971031_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP033342

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP033340

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection