CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP033606	Lactococcus lactis strain IL6288 chromosome, complete genome	2 crisprs	cas3,DEDDh,csa3,DinG	0	0	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP033606_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033606_1

1283366-1283544

Orphan

Consensus_repeat	Method
GATAAAATGCTCATGTTAATCGCATTACTGACAGAAAGTTCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033606_1

>merge|CP033606|1|1283366-1283544|CRISPRCasFinder
GATAAAATGCTCATGTTAATCGCATTACTGACAGAAAGTTCAGATTGCTGAACCTTCTTTTATTCATCGATAAAATGCTCATGTTAATCGCATTGCTGACAGAAAGTTCAGCTTGCTGAACCTTCTTTTATTCATCGATAAAATGCTCATGTTAATCGCATTGCTGACAGAAAGTTCAG

>CP033606|1|1|1283366-1283544|CRISPRCasFinder
GATAAAATGCTCATGTTAATCGCATTACTGACAGAAAGTTCAG	ATTGCTGAACCTTCTTTTATTCATCGATAAAATGCTCATGTTAATCGCATTGCTGACAGAAAGTTCAGCTTGCTGAACCTTCTTTTATTCATC
GATAAAATGCTCATGTTAATCGCATTGCTGACAGAAAGTTCAG

Protein	Signature genes	Signature genes Name	Protein_function
CP033606.1\|AYV50891.1\|1288087_1288873_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
CP033606.1\|AYV50880.1\|1276553_1277495_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
CP033606.1\|AYV50894.1\|1290072_1290942_-\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|368712
CP033606.1\|AYV50881.1\|1277565_1277973_+\|transporter	unknown	unknown	gnl\|CDD\|227646
CP033606.1\|AYV50883.1\|1278490_1279450_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
CP033606.1\|AYV50887.1\|1282516_1283305_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|99814
CP033606.1\|AYV50886.1\|1280645_1281359_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
CP033606.1\|AYV50893.1\|1289777_1290104_-\|DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
CP033606.1\|AYV50879.1\|1275484_1276510_+\|glycerol-3-phosphate-dehydrogenase-(NAD(P)(+))	unknown	unknown	gnl\|CDD\|234629
CP033606.1\|AYV50888.1\|1283839_1285204_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
CP033606.1\|AYV50896.1\|1291806_1292151_-\|hypothetical-protein	unknown	unknown	unknown
CP033606.1\|AYV50892.1\|1288902_1289460_-\|rRNA-large-subunit-pseudouridine-synthase-E	unknown	unknown	gnl\|CDD\|211334
CP033606.1\|AYV50895.1\|1291019_1291832_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
CP033606.1\|AYV50889.1\|1285580_1286792_+\|virion-core-protein	unknown	unknown	gnl\|CDD\|226711
CP033606.1\|AYV50882.1\|1277969_1278500_+\|heptaprenyl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|227110
CP033606.1\|AYV51747.1\|1281508_1282444_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982
CP033606.1\|AYV50890.1\|1286951_1288091_+\|TFIIB-type-zinc-ribbon-containing-protein	unknown	unknown	gnl\|CDD\|369254
CP033606.1\|AYV50884.1\|1279446_1280163_+\|ribosomal-RNA-small-subunit-methyltransferase-G	unknown	unknown	gnl\|CDD\|223434
CP033606.1\|AYV50885.1\|1280392_1280644_-\|hypothetical-protein	unknown	unknown	unknown
CP033606.1\|AYV50897.1\|1292197_1293202_-\|DUF916-domain-containing-protein	unknown	unknown	gnl\|CDD\|368712

Protein	Function_ID	Function_description	E-value
CP033606.1\|AYV50891.1\|1288087_1288873_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.58524e-71
CP033606.1\|AYV50880.1\|1276553_1277495_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	1.35337e-172
CP033606.1\|AYV50894.1\|1290072_1290942_-\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|368712	pfam06030, DUF916, Bacterial protein of unknown function (DUF916). This family consists of several hypothetical bacterial proteins of unknown function.	1.73883e-42
CP033606.1\|AYV50881.1\|1277565_1277973_+\|transporter	gnl\|CDD\|227646	COG5341, COG5341, Uncharacterized protein conserved in bacteria [Function unknown].	1.24753e-52
CP033606.1\|AYV50883.1\|1278490_1279450_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	9.30264e-84
CP033606.1\|AYV50887.1\|1282516_1283305_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|99814	cd06218, DHOD_e_trans, FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+. In L. lactis, DHOD B (encoded by pyrDa) is co-expressed with pyrK and both gene products are required for full activity, as well as 3 cofactors: FMN, FAD, and an [2Fe-2S] cluster.	1.45438e-109
CP033606.1\|AYV50886.1\|1280645_1281359_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	3.7665e-134
CP033606.1\|AYV50893.1\|1289777_1290104_-\|DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	6.48052e-05
CP033606.1\|AYV50879.1\|1275484_1276510_+\|glycerol-3-phosphate-dehydrogenase-(NAD(P)(+))	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	1.94654e-180
CP033606.1\|AYV50888.1\|1283839_1285204_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.89894e-53
CP033606.1\|AYV50892.1\|1288902_1289460_-\|rRNA-large-subunit-pseudouridine-synthase-E	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	1.86593e-99
CP033606.1\|AYV50895.1\|1291019_1291832_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.15853e-29
CP033606.1\|AYV51747.1\|1281508_1282444_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	0
CP033606.1\|AYV50882.1\|1277969_1278500_+\|heptaprenyl-diphosphate-synthase	gnl\|CDD\|227110	COG4769, COG4769, Predicted membrane protein [Function unknown].	1.74231e-64
CP033606.1\|AYV50889.1\|1285580_1286792_+\|virion-core-protein	gnl\|CDD\|226711	COG4260, COG4260, Membrane protease subunit, stomatin/prohibitin family [Amino acid transport and metabolism].	4.46487e-169
CP033606.1\|AYV50890.1\|1286951_1288091_+\|TFIIB-type-zinc-ribbon-containing-protein	gnl\|CDD\|369254	pfam07191, zinc-ribbons_6, zinc-ribbons. This family consists of several short, hypothetical bacterial proteins of around 70 residues in length. Members of this family have 8 highly conserved cysteine residues, which form two zinc ribbon domains.	0.000852226
CP033606.1\|AYV50884.1\|1279446_1280163_+\|ribosomal-RNA-small-subunit-methyltransferase-G	gnl\|CDD\|223434	COG0357, GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane].	2.20408e-85
CP033606.1\|AYV50897.1\|1292197_1293202_-\|DUF916-domain-containing-protein	gnl\|CDD\|368712	pfam06030, DUF916, Bacterial protein of unknown function (DUF916). This family consists of several hypothetical bacterial proteins of unknown function.	7.0595e-28

>CP033606.1|AYV50887.1|1282516_1283305_-|dihydroorotate-dehydrogenase
MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSWDKVAKTCTILYRIGDETSGTYEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAELKNVSLKIATDDGSYGTKGHVGMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKEDENHALKVCEDGPVFLGKQLLL
>CP033606.1|AYV51747.1|1281508_1282444_-|dihydroorotate-dehydrogenase
MTENNRLSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPTPRVAETASGMLNAIGLQNPGLEVIMAEKLPWLNENFPDLPIIANVAGSEEDDYVAVCAKIGDAPNVKVIELNISCPNVKHGGQAFGTDPDVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEAAGADGLTMINTLMGVRFDLKTRKPVLANITGGLSGPAIKPVALKLIHQVAQVVDIPIIGMGGVESAQDVLEMYMAGASAVAVGTANFADPFVCPKIIEKLPEVMDQYGIDSLENLIQEVKNSKK
>CP033606.1|AYV50886.1|1280645_1281359_-|orotidine-5'-phosphate-decarboxylase
MQENRPVIALDFPEFSDVKDFLEKFDPSEQLYIKLGMELFYTAGPQVVYYVKSLGHSVFLDLKLHDIPNTVESSMHVLARLGVDMVNVHAAGGVEMMVAAKRGLEAGTPVGRQRPKLIAVTQLTSTSEEIMQNDQKIMTSLEESVINYAQKTAQAGLDGVVCSAHEVEKIKAATSKEFICLTPGIRPEGASKGDQKRVMTPKEARTIGSDYIVVGRPITQAKDPVASYHAIKAEWNR
>CP033606.1|AYV50885.1|1280392_1280644_-|hypothetical-protein
MKKLLHFLVVLLGIFVAFILARLFIEIYTIVGDVYLQVDNKTITLYKVLAEIDYLSVGITFAMVFAYMAPIRLNCCRRRKIMV
>CP033606.1|AYV50884.1|1279446_1280163_+|ribosomal-RNA-small-subunit-methyltransferase-G
MTPDEFLSALTEFDIQLSDKQIKQFERYFELLVEWNEKINLTAITEKNEVYLKHFYDSIAPILYGLITDQPVSILDIGAGAGFPSLPMKIIFPELKVTIIDSLNKRINFLSLLTEELGLENVTLLHGRAEDFGQDANYRGTFDFVTARAVARLSVLTEFTIPFLKKNGILLSLKAAQFEEELNDAKKAIATLGGKFIKEVAYELPNGDERHIALIEKKKETPKKYPRKAGTPAKNPIK
>CP033606.1|AYV50883.1|1278490_1279450_+|polyprenyl-synthetase-family-protein
MDLKNNFWKDYPELEKELVQVQQLMKSHVTIKNSDVKSAIFDIFDAGGKMLRPAYLLLFSGFTDLSESERLALAASVEMMHTATLVHDDVIDHADTRRGVATLSAKYGPEIAVYAGDYLFIAVFRLMSEHSLELSNLTKNIGSIERLLGGELGQLNHHFNLQQTLDDYIENISGKTGELFALSASVAPLISKNNTLTKRAYKIGMNIGISFQIMDDYLDYASTAQTLGKPVLEDIKQGIYSAPVLFALQENNALVSELIKNEKFDEVYDFIKTSDALEKTKALAKSYTLSALNLIDKLPKGKNRELIAEITRKLLERTL
>CP033606.1|AYV50882.1|1277969_1278500_+|heptaprenyl-diphosphate-synthase
MNIKEYVYVSLLTAAAVVMGIIESSLPPFFAFAPGAKVGLANLVMIIAVFTLRWRQVWVMQILRLLITALFTGFSVFLYSFAGGILSLLAMYLMKQFGPKLVSMIGISTVGGFFHNFGQLAMASLLAKTTSVMLYLPWLAFFGILAGFAIGIAGNQLITRVKPIQELFIKESKQWT
>CP033606.1|AYV50881.1|1277565_1277973_+|transporter
MNFFKNTVNFFKSIKTKPLDFVIIFLLFIASFSTLFFFATGSKGAQAELRISGKVIKTFNLNKNQTWTYRDKDGDYNKIQVKNGEIAVVEANCKDQIDVQRGYISKTGETIVCLPHNLVIEVMSGQKDEQVDYKV
>CP033606.1|AYV50880.1|1276553_1277495_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKQNIIPTKARKVRKAVIPAAGLGTRFLPATKAIAKEMLPIVDKPTIQFIVEEALKSGIEDILIVTGKAKRPIEDHFDSNIELEQNLLEKGKTELLKLVEETTDINLHFIRQSHPKGLGHAVLQAKAFVGNEPFVVMLGDDLMNITGNETPLTKDLINDYEKTHASTIAVMKVPHDDVDKYGVIDPNGEVSKGLYNVERFVEKPNVDEAPSDLAIIGRYLLTPEIFDVLETQVPGAGNEIQLTDAIERLNKTQRVFAHEFTGKRYDVGDKLGFVETTIEYGLEHPQIGANLKNYIIEKAKELSKDDSKNITKK
>CP033606.1|AYV50879.1|1275484_1276510_+|glycerol-3-phosphate-dehydrogenase-(NAD(P)(+))
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEKIKAFDRLDLALEDVDAILFVVPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKDHDEAKYAQAIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLGIDMPITETIYKVLYENLDAKTGILDIMRRETRAENEFINNK
>CP033606.1|AYV50888.1|1283839_1285204_-|MFS-transporter
MNKNNHFHLLGAVIATGILSFSGVLIETAMNVTFPTLINEFGLSTSKIQWVTTIYLLVIAITIPLSSYFNERFSARKLFLVANLIFLVGVLTNCFSPNFAMLLFGRLLQGVGTGIGLPLMFHLILTKAPLHKRGMMMGIGTLTTSIAPAIGPTYGGIISNSLDWRYIYIFLLPLVVISLVLGLACLPREGEKTPKKLALRPVIALSIMFFAFISALSAEHLMTFALLFIVGLVGAFLFVQFNRKESLIDLGILKNHRFVALIFSLLVYQALLLGLSFVLPSFIQVSAGFSSSVAGLFMFSGALIGAVLAPISGKVLDQIGARKPITTGLILAALGLALIFVFLPTKSLALLLGAHIVLMLGLGISYSNLMTCSLSTLATDQLSDGNALVNTLQQFIGAVATAVVATTLSIFQGLNGFKVGTSHGTSIILALFFILIIVSLIVSFPNLKKIRANH
>CP033606.1|AYV50889.1|1285580_1286792_+|virion-core-protein
MGIIKAATGSLGGALADQWLEVIEPNEMSDQTVFTKGIKVRKDAKRGSNRKGTEDVITDGSIVHVYENMMMILVDGGKIIDYTAEPGYYTVKNDTAPSLFNGDLRDSIQESFFRFKFGGTTPQKQEVYYVNLQEIKGIKFGTATPLQYFDNFYNAELFLRTHGTYSIKITDPLAFYANVIPKNADHVEIQEINDQYLAEFLTALNTSINQYSAQGERVSFLTSKSMELSKYMASVLDEDWKQLRGMEIVSVAVASISYTDDSQKLINMRNQGAMLGDPSIREGFVQGAVARGLEAAGSNTGGATNAFMGMNMGGQNLAGFSQTNQAQMQAQAENKADTWTCPECNTKNTGKFCSNCGQAKPSATPVMPELNMACNECGAVVNLANGVPKFCPECGKPFVAKAL
>CP033606.1|AYV50890.1|1286951_1288091_+|TFIIB-type-zinc-ribbon-containing-protein
MSESQVLTHKCPNCGGPLLFEPKNQKFHCEYCGSTFTEQEVSDFEAKQEAAKVTDSPISSVSNAETTDEKEKITDSDQKRADENTDEEIGLFLCPSCGAEIVTDATTASTWCYYCHNPVVLTERLSGKFLPEKILPFQIERKAAEEQFLDWVGKKKFVPKAFFDKKQIQNLSGVYFPYWAVDAELSGGISAQATNLRVWIVGDTEYTEHSQYEIQRGGETKFKDLIKNALKKNLSDKMVGAVQPFDMTAAIPFKNQYLSGFLTEKRDIEFPDMKENVEREFRQYADGLMESTIIGYTSVSNLQSNQQIKNIDEDYVLLPIWLVTYKEAGNDRLFYYAMNGQTGKVAGLLPIDKKKLWTVAIGIFILVLLLGIIVGYLLS
>CP033606.1|AYV50891.1|1288087_1288873_+|YgcG-family-protein
MRKKLVFLSLFFLSFFFLLLAPKTAAATFSSGLEDNLQLLGGNVTLLEQEAQKLANETKAGVYVVTTDSSTPASQMAKTYLADKVGAKNNGVVLVINMNLRKVYIWATGNLKYYLPSSRIEKTLDIVQPELTDNNYYQAVSGFFDQVSKYYQAGIPTSRKYSINSETGAVTFHRSFQPLSILIALIISLIAAGGFVWAIYRRYQMKDAHAVWRYDYGRNGNLELHQREDILVNTFITTRIIPRPSSDNNNFSDGSGGGRSF
>CP033606.1|AYV50892.1|1288902_1289460_-|rRNA-large-subunit-pseudouridine-synthase-E
MNFCKKIMIILFNKPYDVLTKFTDGEGRKTLKDYIKIPNVYAAGRLDKDSEGLLLLTDDGKLNHLLTDPKSKSYKTYLVQVEGEFSPEAAQKLQKGLLLKDGKTLPAKVKLIDEPDWLWERTPPIRERKAIPTSWVEISIKEGKNRQIRRMTAAVGFPTLRLIRWSIGQYSLGNLKSGEYKIIQK
>CP033606.1|AYV50893.1|1289777_1290104_-|DUF3324-domain-containing-protein
MPERIIKGKYEAQVDNKTARYKYQWTFDQEFTISDNQAQKLNDSDPTVKKEKDWTWRLFVIGILLLVLFLIILLWKRRKKSQKEEEEKQALREKIEAQEKIIDDLNKK
>CP033606.1|AYV50894.1|1290072_1290942_-|DUF916-and-DUF3324-domain-containing-protein
MKKLQLFLSAIFLTLSFGLAQTGYARTDDYTVKPIIPENQSNKDLGYFDILLGADKEQTLQVELSNNTEQEIKIDVTLSSAVTNMTGLVVYEPTEIVADSSLKYNLKDYVNTPKVVTLPPLTRQKLDLKVKMPNEAFDGQIAGGITFSKEGQNDKEEDSEGITVKNTYSYTIALLMRQNDNEVSPDLKLKTVSPSQINGRNVINVNLQNPTMTYINTMNVKATISGISNTDIKYTYSNSMMQMAPNTSFDLPIPTSNQSAATRVSEPLKPGKYRLQLVVNARTDNQRKI
>CP033606.1|AYV50895.1|1291019_1291832_-|WxL-domain-containing-protein
MKKTILSLSGVAVITATLLSTSVLEVSAASVGSTTSGANVAFQPKKTPTNPVSPGDGKTPISPTTPGVPNTSNPVASDDGLTLDYVPAINFGTHYVDASTAHTWSAWAANDGSGKAIPQFLQVTDNRGTATGPTGWSVSLTQTAQFKGTKAGDLVNAVMTFNNDKTNTVVSTSMNKASSTVNTATNALVPGTAVNIFQADAGTGTGTNLLSFGAGDGSTLVTDPETLDSATNTTGKVDPNITLNVPAGSAKVDTYTTTLNWNLYSAPGNA
>CP033606.1|AYV50896.1|1291806_1292151_-|hypothetical-protein
MKIKYILWVICALLLLNTSVILAQEIGGTNTTGKVGFLEKEPIEKPPVTSSSQATGQSQILTNQNLPIVGTNQNDSLMPFVVGLVTIGVGSLMIKKTKRIRIKENFNEKNNTQP
>CP033606.1|AYV50897.1|1292197_1293202_-|DUF916-domain-containing-protein
MKKVYKLIFLSILSILLIVQSKVAYSESPTSDFSVEAILEGHQKDKSITYWWLQVEKTQSINLKLKISNGNEENNFEITSNQAVNNNNFTLDYSLSAEEVSQYLHHKNSNFNFYQDIYFDETQEAGKLKITLAPNEVREITINLKIPKEGIKGQLIGGINVTKVPKESDRQEGILNVYSNVVALVMEDKDYSESHKQNLEFALEKSNEKEQVIKIKNSNSFLLSNMNIKAVIKDQKGEVVSEFSNPKTAVVPNASVSIKLNNQKELVKGAKYYLTVDSSNQTFKRNLIVSDSGNLKILEKKKEEIQPLNKKSVGLSLILMVVISSGGIYAYFKK

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Crispr_ID: CP033606_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033606_2

1704582-1704676

Orphan

Consensus_repeat	Method
TTTATTACTGACAGACTTGTCAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033606_2

>merge|CP033606|2|1704582-1704676|CRISPRCasFinder
TTTATTACTGACAGACTTGTCAGCTTTGCTGACAAATCCTTCATCCATTGATAAAAAGCTCAATTCAATCGCTTTTTACTGACAGACTTGTCAGC

>CP033606|2|2|1704582-1704676|CRISPRCasFinder
TTTATTACTGACAGACTTGTCAGC	TTTGCTGACAAATCCTTCATCCATTGATAAAAAGCTCAATTCAATCG
CTTTTTACTGACAGACTTGTCAGC

Protein	Signature genes	Signature genes Name	Protein_function
CP033606.1\|AYV51253.1\|1701103_1701397_+\|hypothetical-protein	unknown	unknown	unknown
CP033606.1\|AYV51256.1\|1703148_1704561_-\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
CP033606.1\|AYV51254.1\|1701393_1702140_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
CP033606.1\|AYV51257.1\|1704794_1705253_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
CP033606.1\|AYV51262.1\|1710742_1711444_-\|adaptor-protein-MecA	unknown	unknown	gnl\|CDD\|227199
CP033606.1\|AYV51261.1\|1709408_1710740_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
CP033606.1\|AYV51265.1\|1713141_1714050_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
CP033606.1\|AYV51259.1\|1707069_1708326_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
CP033606.1\|AYV51247.1\|1696389_1696695_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226801
CP033606.1\|AYV51248.1\|1696711_1697683_-\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|237010
CP033606.1\|AYV51258.1\|1705852_1707070_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
CP033606.1\|AYV51252.1\|1700766_1701129_+\|hypothetical-protein	unknown	unknown	unknown
CP033606.1\|AYV51264.1\|1712307_1712994_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
CP033606.1\|AYV51251.1\|1699633_1700782_+\|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl\|CDD\|273881
CP033606.1\|AYV51260.1\|1708463_1709234_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
CP033606.1\|AYV51250.1\|1698402_1699644_+\|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl\|CDD\|341288
CP033606.1\|AYV51762.1\|1705368_1705851_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223659
CP033606.1\|AYV51249.1\|1697688_1698258_-\|biotin-transporter-BioY	unknown	unknown	gnl\|CDD\|224187
CP033606.1\|AYV51263.1\|1711573_1712308_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
CP033606.1\|AYV51255.1\|1702162_1703008_+\|2-nitropropane-dioxygenase	unknown	unknown	gnl\|CDD\|132195

Protein	Function_ID	Function_description	E-value
CP033606.1\|AYV51256.1\|1703148_1704561_-\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
CP033606.1\|AYV51254.1\|1701393_1702140_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	4.80083e-73
CP033606.1\|AYV51257.1\|1704794_1705253_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	9.34852e-67
CP033606.1\|AYV51262.1\|1710742_1711444_-\|adaptor-protein-MecA	gnl\|CDD\|227199	COG4862, MecA, Negative regulator of genetic competence, sporulation and motility [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion].	3.81196e-86
CP033606.1\|AYV51255.1\|1702162_1703008_+\|2-nitropropane-dioxygenase	gnl\|CDD\|132195	TIGR03151, enACPred_II, putative enoyl-[acyl-carrier-protein] reductase II. This oxidoreductase of the 2-nitropropane dioxygenase family (pfam03060) is commonly found in apparent operons with genes involved in fatty acid biosynthesis. Furthermore, this genomic context generally includes the fabG 3-oxoacyl-[ACP] reductase and lacks the fabI enoyl-[ACP] reductase.	3.58449e-84
CP033606.1\|AYV51259.1\|1707069_1708326_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	9.30838e-131
CP033606.1\|AYV51247.1\|1696389_1696695_-\|hypothetical-protein	gnl\|CDD\|226801	COG4357, COG4357, Zinc finger domain containing protein (CHY type) [Function unknown].	1.12966e-28
CP033606.1\|AYV51248.1\|1696711_1697683_-\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	8.8094e-70
CP033606.1\|AYV51261.1\|1709408_1710740_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	4.68381e-85
CP033606.1\|AYV51264.1\|1712307_1712994_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.09368e-76
CP033606.1\|AYV51251.1\|1699633_1700782_+\|acetyl-CoA-C-acyltransferase	gnl\|CDD\|273881	TIGR01930, 3-ketoacyl-CoA_thiolase, acetyl-CoA acetyltransferases. This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other].	4.30804e-158
CP033606.1\|AYV51260.1\|1708463_1709234_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.57723e-148
CP033606.1\|AYV51250.1\|1698402_1699644_+\|long-chain-fatty-acid--CoA-ligase	gnl\|CDD\|341288	cd17633, AFD_YhfT-like, fatty acid-CoA ligase VraA. This family of acyl-CoA ligases includes Bacillus subtilis YhfT, as well as long-chain fatty acid-CoA ligase VraA, all of which are as yet to be characterized. These proteins belong to the adenylate-forming enzymes which catalyze an ATP-dependent two-step reaction to first activate a carboxylate substrate as an adenylate and then transfer the carboxylate to the pantetheine group of either coenzyme A or an acyl-carrier protein. The active site of the domain is located at the interface of a large N-terminal subdomain and a smaller C-terminal subdomain	3.2301e-68
CP033606.1\|AYV51762.1\|1705368_1705851_-\|hypothetical-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	3.28577e-22
CP033606.1\|AYV51265.1\|1713141_1714050_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	2.39571e-70
CP033606.1\|AYV51249.1\|1697688_1698258_-\|biotin-transporter-BioY	gnl\|CDD\|224187	COG1268, BioY, Uncharacterized conserved protein [General function prediction only].	5.72661e-47
CP033606.1\|AYV51263.1\|1711573_1712308_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.02808e-157
CP033606.1\|AYV51258.1\|1705852_1707070_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0

>CP033606.1|AYV51256.1|1703148_1704561_-|Fe-S-cluster-assembly-protein-SufB
MTENSTQEVVKDLEEYKFGFHDNAELEFTTGLGLTEEVIREISETKNEPEWMLEFRLKSFEAFKKLDMPKWGPDLSGIDFNDIVYYQKPSAKAARSWEDVPQEIKDTFEKIGIPEAERSYLAGASAQYESEVVYHNMKDEFEKLGIIFTDTDSGLRDYPEIFKKYFSKLVPPTDNKLAALNSAVWSGGSFVYVPKGVKCEIPIQAYFRINNEKSGQFERTLIIVEEGASIQYVEGCTAPTYSASSLHAAVVEIFVEEGGYMRYSTIQNWSDNVYNLVTKRAAAEKNATVEWIDGNLGSKVSMKYPAVHLNGPGARGTMLSIAFAGANQNQDTGAKMIHNAPNTSSSIISKSIAKNGGAVNYRGQVTFGKNSKKSASHIECDTILMDDLSKSDTVPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLTEKEATDMIVMGFIEPFTKELPMEYAVELNRLISYSMEGSIG
>CP033606.1|AYV51255.1|1702162_1703008_+|2-nitropropane-dioxygenase
MTWYHELGIKYPLFQGGMAWASNAELVAAVSNNGALGIIGSGGRTANELRRMIRKTKTLTSQPFGVNLMLLDKNIKQLLEVICEEKISVVTTGAGSPKEIIDTIIANNIKLFPVVPNKEIALKMLNLPISGIIVEGNEAGGHVGSQNLASLLKEIAPICPLPLIAAGGIYDHHTASLANILGANGVQVGTAFLLAKECQISPIYQELICKGEENGTSLISDKNGHLTRLLNISSEYPLNKSLKAAVEKGDLINGAFMAGSSSAYLEKIEPVENIIQRIMKK
>CP033606.1|AYV51254.1|1701393_1702140_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNKRTILITGATRGIGWAIAQKAAQANHKVILTGRDPLSLKSRAEELKKKFPKTEIQAIPLDVSNRSSVANAAKLIKDIDILINNAGITADSTFKKMSPEIWDEVISVNLTGVFNSTHALLDKINQGGQIITLTSKSALFGNFGQANYAASKAGIIAFTKTLAKELQKSMIRVNSVSPAAVTDMTLPVLKSLKETYGQNIPDEWKMGSSSDVANFIINDLIESEMTGKIFSINGSEIGYWQEPTFHKL
>CP033606.1|AYV51253.1|1701103_1701397_+|hypothetical-protein
MKLYKKINKADLIDYLQSVKDTNSLHYGKNPIIPGNFLLFILEEMYQEFYSMPLSYLKANFCSPAYLNERFCFIFNQNAFQITDRNQTLILKGEWKQ
>CP033606.1|AYV51252.1|1700766_1701129_+|hypothetical-protein
MVSKMILIAQKSLPRHFKLEGQKNFLSLLPQLWQELEGIPYSLKNGENWLLSEEIIRYPSSNYSFDKLKLYLLSEHITRHSKKYIINLSLEITSNTKLLAQINLSLLSEDSWNEIIQKNQ
>CP033606.1|AYV51251.1|1699633_1700782_+|acetyl-CoA-C-acyltransferase
MSFKNPVGIIAANRLPIGKINGFYKKISPETLYQNLIKQQFNKNLLLKKADIDYIILGNVTNQGGNLARRCALKAGFSSQVPAFTIDQQCGSGLTAMISSANYIISGEASVICTGGVESTSQANIVLDSESYQPINRFKMAPEPYEDFDMGTIADMTALKYNIPRSVQDLYALNSHKKATQAIEGKLLENEVFPYQDEGFTISSDQTVRPKSSMEALSKLTPAFTTNGTATAGNSCPINDGASSIILSSTNNPFDFQGYYLGQTTIALSPSDFLLGPIKATEKLLQKFNLKLNDIEAIELNEAFASQAILFQNYFKLDDIKLNAYGGSLAFGHPYGATGGILISRLLNRLNQVQKPCLGIATLCVAGGMGISVLIGNQWYQK
>CP033606.1|AYV51250.1|1698402_1699644_+|long-chain-fatty-acid--CoA-ligase
MEKNKFNFSKLAALFTDYPALKIGEISYSYQQINDLIQRKLTDYSHSSKTVITLINDSPLNFIIDFLAIIESGNYPLVVDKSFKKKSFKFGLIPEDTLFLASTSGTTGPPKIYYRNWESWKMGFEVCDDLFHLSNSQALATTSPLTTSLGLHTLMCALYLGKTFLTITNPSQFINITENYALFTVPTYLLNNLNELFALTSPEIIFLGGGTLSPEAINKVRKKLPQTQMIEFYGSSETSFISWQAVNEGKKTSSVGKLFPHVELTLGPKYRLTVKSPYLFSGYLNQPYPQSWTTDDLGTLKNNHLYLFGRRSDIIEHGANKIFPEEIERMAKDLCEDCIAFGVFDERYSQKIALLLLKPIEKEKLIKILAQRLPKYKLPQIYLETPTLNFTKNQKISRKELEKEYFRGVYHEL
>CP033606.1|AYV51249.1|1697688_1698258_-|biotin-transporter-BioY
MTKNQKVKTLTYSAFMTAFIIILGFLPGIPIGFIPVPIILQNMGIMMAGGLLGPKYGTISVGAFLTLALIGLPVLTGGNGGAASFLGPSGGYRMAWLFTPFLIGFFLKKLQITASKNWIGELIIVLVFGVIFVDLVGAIWLSIQSNIPLITSLISNLVFIPGDCIKAILTVLIVRRLRKEGGFEMYFRK
>CP033606.1|AYV51248.1|1696711_1697683_-|biotin--[acetyl-CoA-carboxylase]-ligase
MRTTKQFVLLKLLQQKGNWVSGDELAEELKLSRESIWKAINTLKRKGNQIESRKNLGYKYVGNESLDEDTINFYSGMKFEDKIFVFDEVTSTQELAKQYLSSHEVKQPFIFVANNQTEGHGRRGRNFYSPSDTGLYFSLILPNPSHDILKIGLLTTSTAVAVVKVLEQFYKDKNFQLKWVNDIYLGTYKVGGIITEAALDLESSSAGNFIMGIGLNLSTKDFPADLSEKAQGINPEFKIDRNQLLAEMAKEVINNFANYRQPDLIDEYRKRSLLFGKNVTLKLGTKAVNGKVEGISDDGSLILKAKSGELQTFKSGEVVKVDW
>CP033606.1|AYV51247.1|1696389_1696695_-|hypothetical-protein
MREKIWGKVIDEEGRCTHYHQENDIVALKCSDCEKYFSCYHCHDELENHLFRATDKEDFPVLCGHCGKKLNFNDYSRGECIKCSSAFNPNCHRHWQVYFNE
>CP033606.1|AYV51257.1|1704794_1705253_-|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSKLDNLYRAVILDHSSNPRHAGELQTGCMVDLNNPTCGDVIRLTVEFENDVISNIAFSGHGCTISTASASMMTVAVLGKTKEEAKELATIFSAMVTGETDERQEKLGDAQFLAGVSKFPARVKCSTLAWNALKKAIDVGEAQETVIHGE
>CP033606.1|AYV51762.1|1705368_1705851_-|hypothetical-protein
MLNWVASLPLWLATTFLFVVVFFRAQCTFWLGKLSYHGILKTKWGKKLEKNSETSAGILAIQKMGWPIIPLSFLTVGFQTAVQFGAGLTNWSWYKYTLAAIPGYLAWGFIYASGGLSLFRSLVQGSIGLLILFIIIILAVVIAANLVLRYIRKNGIKTDD
>CP033606.1|AYV51258.1|1705852_1707070_-|cysteine-desulfurase
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRQFINAKSTKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKDGQLDMDDLRKKITNQTKFVSIAHVSNVLGTINPVEEITKIAHEHGAYMAVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQFEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEIELIDYLMPKLQEIEGLKIYGPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKEFFNLD
>CP033606.1|AYV51259.1|1707069_1708326_-|Fe-S-cluster-assembly-protein-SufD
MNQEILNFSQMHAEPAWLSDLRQKAALEFENLELPNIERVKINRWGLDHLSISENEEIGSVPTFTEIPNHPLLVQVGSQTVMEQMTPNLAEQGVIFTDFNSALTEIPELLEENFGSVVPFNESRLTAANTVTFNSGLVLYVPDGVEVLEPIESILMQEGSSEVPFNKRILIIVGKNAKVDYLERLETSDEQSSKAKANIVVEVIAKAGAQVKFAAIDRLGENVTASVVRRGLIGDNATVDWSVGVMNDGNVVADFDSDLKGNGSHSQIKVVGISTGHQTQGIDTRVTNFGLNSVGHILQNGVILDKGTLTFNAIGHIIKGAKNADAQQSSHVLMLSDKGRGDANPILLIDENEVTAGHAASVGQVDEEDLFYLQSRGLDEETAKRLVIRGFLGSVVSEIPVKSVQAEFIETIERKLGM
>CP033606.1|AYV51260.1|1708463_1709234_-|Fe-S-cluster-assembly-ATPase-SufC
MATLEIKNLHVAIEDKEILKGVNLVINTNEIHAIMGPNGTGKSTLSAAIMGNPNYSVTQGEVLFDGQNVLEMSVDERARLGLFLAMQYPSEIPGITNAEFLRAAMNAKRAEDDKVSVMEFIKKLDKNMEVLSMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPTFAILDEIDSGLDIDALKVVAKGVNSMRGEKFGALIITHYQRLLDYITPDVVHIMMDGRVVKTGGAELAKRLETEGYVNIAEELGLEYKEEV
>CP033606.1|AYV51261.1|1709408_1710740_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MVDTLKEIPFALKFLIVIIITFGISVILTPIMTFVSKAIGAVDKPNERRVNKKPMPSAGGLVIFIAFAIATLFILPHIVHNQPPIHSQPPVHGASHQPIQLVSYFSYIWPFIVGAGIVVLTGLIDDIKEISPKMKLLGLTVAASFIWFFTNARFDNLKIPFGGPLLIFPAWLSFIFTVFWILAITNAINLIDGLDGLASGVSIISLTTMGIVSYFFLPSPNVFLPITIFIMVAAIMGFFPYNYHPAIIYLGDTGALFLGFIISVASLQGLKNATAVAVLTPLLILGVPITDTIMAMVRRKLNRQSIATADKRHLHHRLMALGFTHRGAVLVIYGIASIFAFISILLQFSSRIGGILLVIACLFGLEIFIELVGILGENRQPVLKALKFVGNSSYRDKVLHSDEDADIDENEEDIGNHSMIDEEIDEPTQEFPIQNYRRSRNKK
>CP033606.1|AYV51262.1|1710742_1711444_-|adaptor-protein-MecA
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAMLGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKNVKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI
>CP033606.1|AYV51263.1|1711573_1712308_-|amino-acid-ABC-transporter-ATP-binding-protein
MNEYLIEIKNLHKYFGKNEVLKGLDIQIKKGEVVVMIGPSGSGKSTFLRTMNLLEKPTDGQVYFEGVNIADKSVDVFKHREKMGMVFQQFNLFPNMTVLENLCLAPVKTGKMTKEEAKKTAEDLLQRVGLSDKAEAYPQALSGGQQQRVAIARALAMNPDVMLFDEPTSALDPEMVGEVLAVMQELAKEGMTMVVVTHEMGFAKTVADRVLFMADGTIVEQGKPAQVFDSPKEKRTQDFLAKVL
>CP033606.1|AYV51264.1|1712307_1712994_-|amino-acid-ABC-transporter-permease
MNFDFLPKYLPYFNDGMIVTILISAFVVLIGTLLGIVTALAKISKIAPLRWLANIYIEIFRGTPMLVQIMLGFGLMGSLSLPTFQVGILQQDLGRLIPGIIVISLNSGAYMAEIVRAGIEAVPLGQKEAAYSLGIRPRQAMATVILPQALRNILPAVGNEFVTIIKDSSLLYTIGVMEVFNGAQTVANLTYQTISPMLFVALYYFVVTFVVSRLLVLFEKKLGKGYAK
>CP033606.1|AYV51265.1|1713141_1714050_-|diacylglycerol-kinase-family-lipid-kinase
MTYYLLANPNSGAGKGARTLETLIPYLEKNNYEYRLFKTKAAGEEGALVRQILDLKNPDDHLVIIGGDGTISLVINELPEEEAFSYIPSGSGNDFARSLKLKLDPIESFEAARRGINHEIFIMNYQSKGLSGYALNNIGIGLDATIVKSANEGKLKQVLNKLKLGSFSYILTALHVLITKKPFPALIEVENQEISLENAFLMTFTKHPYFGGGVKISPEATNENADIHLVEYNKHHLLRTFSLIPSVLRGMHLKHPLFLHRVSPQFSVELAESQPVQIDGEIHELVAADRLSISTERRMIIY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13280 : 126262

105

Bacillus_phage(26.09%)

tRNA,protease,bacteriocin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV49772.1\|13280_15272_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
AYV49773.1\|15273_15909_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-24	36.0
AYV49774.1\|16109_16580_+	hypothetical protein	A0A097BYE2	Leuconostoc_phage	4.0e-10	30.1
AYV49775.1\|16597_17164_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
AYV49776.1\|17164_20650_+	transcription-repair coupling factor	NA	NA	NA	NA
AYV49777.1\|20809_21280_+	hypothetical protein	NA	NA	NA	NA
AYV49778.1\|21350_21668_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
AYV49779.1\|21696_22071_+	septum formation initiator family protein	NA	NA	NA	NA
AYV49780.1\|22070_22394_+	RNA-binding protein	NA	NA	NA	NA
AYV49781.1\|22531_23881_+	serine hydrolase	NA	NA	NA	NA
AYV49782.1\|23877_25149_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
AYV49783.1\|25129_25681_+	hypoxanthine-guanine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	1.8e-09	29.7
AYV49784.1\|25886_27974_+\|protease	ATP-dependent zinc metalloprotease FtsH	G8DDJ2	Micromonas_pusilla_virus	5.4e-107	49.2
AYV49785.1\|30921_32859_+	transcription antiterminator	NA	NA	NA	NA
AYV49786.1\|32906_33338_+	PTS mannitol transporter subunit IIA	NA	NA	NA	NA
AYV49787.1\|33475_34633_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
AYV49788.1\|35250_35700_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYV49789.1\|35776_36019_+	TM2 domain-containing protein	NA	NA	NA	NA
AYV49790.1\|38970_40118_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-46	41.0
AYV49791.1\|40669_41191_+	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	6.0e-31	42.9
AYV49792.1\|41654_42830_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AYV49793.1\|42928_43684_+	DNA repair protein RecO	NA	NA	NA	NA
AYV49794.1\|44041_45460_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	3.0e-40	27.0
AYV49795.1\|45653_47252_-	dienelactone hydrolase	NA	NA	NA	NA
AYV49796.1\|47244_48225_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
AYV49797.1\|48227_49352_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
AYV49798.1\|49440_50442_-	lipoate--protein ligase	NA	NA	NA	NA
AYV49799.1\|50641_51487_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	1.7e-11	31.0
AYV49800.1\|51567_52218_-	HD domain-containing protein	A0A1S5XYU7	Kurlavirus	4.4e-15	31.4
AYV49801.1\|52334_53360_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AYV49802.1\|53861_54299_+	OsmC family peroxiredoxin	NA	NA	NA	NA
AYV49803.1\|54459_55773_+	APC family permease	NA	NA	NA	NA
AYV49804.1\|55832_56183_+	hypothetical protein	NA	NA	NA	NA
AYV49805.1\|56241_57237_-	phosphate acyltransferase PlsX	NA	NA	NA	NA
AYV49806.1\|57339_58152_-	HAD family hydrolase	NA	NA	NA	NA
AYV49807.1\|58277_59915_-	ABC-F family ATPase	A0A2K9L3Z8	Tupanvirus	5.3e-49	25.9
AYV49808.1\|61042_62323_-	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	A0A2I2L687	Orpheovirus	1.4e-09	26.9
AYV49809.1\|62549_63383_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AYV49810.1\|63783_64251_+	universal stress protein	NA	NA	NA	NA
AYV49811.1\|64379_64577_+	DUF4649 domain-containing protein	NA	NA	NA	NA
AYV49812.1\|64607_65228_+	alpha/beta hydrolase	NA	NA	NA	NA
AYV49813.1\|65278_66448_+	ring-cleaving dioxygenase	NA	NA	NA	NA
AYV49814.1\|66458_67049_+	flavin reductase family protein	NA	NA	NA	NA
AYV49815.1\|67646_69794_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	7.2e-38	26.5
AYV49816.1\|69808_71230_+	HlyD family secretion protein	NA	NA	NA	NA
AYV49817.1\|71323_71449_+	hypothetical protein	NA	NA	NA	NA
AYV49818.1\|71690_72143_+	transporter	NA	NA	NA	NA
AYV49819.1\|72181_72838_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYV49820.1\|72940_73222_-	hypothetical protein	NA	NA	NA	NA
AYV49821.1\|73231_73384_-	hypothetical protein	NA	NA	NA	NA
AYV49822.1\|73722_73941_+	hypothetical protein	NA	NA	NA	NA
AYV49823.1\|74034_74172_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
AYV49824.1\|74186_74897_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYV49825.1\|75322_75775_+	transporter	NA	NA	NA	NA
AYV49826.1\|76121_77233_-\|transposase	IS3-like element IS981 family transposase	A0A1P8CWQ3	Bacillus_phage	1.2e-49	41.4
AYV49827.1\|77269_77875_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYV49828.1\|79322_79691_+	hypothetical protein	NA	NA	NA	NA
AYV49829.1\|79910_80213_-	hypothetical protein	NA	NA	NA	NA
AYV49830.1\|80214_80382_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
AYV49831.1\|80948_81098_-	50S ribosomal protein L33	NA	NA	NA	NA
AYV49832.1\|81127_81301_-	50S ribosomal protein L32	NA	NA	NA	NA
AYV49833.1\|81664_83446_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.8e-61	29.1
AYV49834.1\|83498_84284_-	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
AYV49835.1\|84338_85598_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	3.5e-93	45.4
AYV49836.1\|85641_86130_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYV49837.1\|86281_86749_+	DUF3013 family protein	NA	NA	NA	NA
AYV49838.1\|86778_88332_+	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	3.0e-46	28.1
AYV49839.1\|88462_88747_+	hypothetical protein	NA	NA	NA	NA
AYV49840.1\|88784_89273_+	DUF1905 domain-containing protein	NA	NA	NA	NA
AYV49841.1\|89290_90244_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
AYV49842.1\|90343_91096_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
AYV49843.1\|91124_92081_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
AYV49844.1\|92281_94504_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	U5J9N6	Bacillus_phage	2.9e-13	28.3
AYV49845.1\|94519_95455_-	glycosyltransferase	V9QJB1	Oenococcus_phage	1.3e-76	49.7
AYV49846.1\|95645_96101_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
AYV49847.1\|96093_97089_+	DUF1211 domain-containing protein	NA	NA	NA	NA
AYV49848.1\|97091_97715_+	HAD family phosphatase	NA	NA	NA	NA
AYV49849.1\|97854_99264_+	amino acid permease	NA	NA	NA	NA
AYV49850.1\|99412_100054_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
AYV51702.1\|100091_100583_-	MarR family transcriptional regulator	NA	NA	NA	NA
AYV49851.1\|100617_101262_-	FMN-dependent NADH-azoreductase 1	NA	NA	NA	NA
AYV49852.1\|101435_104033_+	protein translocase subunit SecA	NA	NA	NA	NA
AYV49853.1\|104161_105199_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	5.3e-47	36.1
AYV49854.1\|105449_105716_+	phosphocarrier protein HPr	NA	NA	NA	NA
AYV49855.1\|105718_107446_+	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
AYV49856.1\|107560_107875_+	hypothetical protein	NA	NA	NA	NA
AYV49857.1\|107915_108215_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
AYV49858.1\|108602_109538_-	alpha/beta hydrolase	W5S4D8	Pithovirus	1.1e-06	26.0
AYV49859.1\|109746_110100_+	multidrug efflux SMR transporter	NA	NA	NA	NA
AYV49860.1\|110221_111385_+	MFS transporter	NA	NA	NA	NA
AYV51703.1\|111826_113020_+	argininosuccinate synthase	NA	NA	NA	NA
AYV49861.1\|113050_114430_+	argininosuccinate lyase	NA	NA	NA	NA
AYV49862.1\|114445_115642_-	MFS transporter	NA	NA	NA	NA
AYV49863.1\|115836_116412_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AYV51704.1\|116563_116917_+	ribonuclease P protein component	NA	NA	NA	NA
AYV49864.1\|116913_117723_+	protein translocase component YidC	NA	NA	NA	NA
AYV49865.1\|117811_118726_+	protein jag	NA	NA	NA	NA
AYV49866.1\|118857_118992_+	50S ribosomal protein L34	NA	NA	NA	NA
AYV49867.1\|120179_120500_+	XRE family transcriptional regulator	NA	NA	NA	NA
AYV49868.1\|120630_120858_+\|bacteriocin	bacteriocin leader domain-containing protein	NA	NA	NA	NA
AYV49869.1\|121035_121581_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYV49870.1\|121633_122314_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYV49871.1\|122482_123629_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-46	41.0
AYV49872.1\|123686_125058_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.6e-54	43.4
AYV49873.1\|125114_126262_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-46	41.0

DBSCAN-SWA_2

380462 : 392593

Streptococcus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV50101.1\|380462_380780_+	thioredoxin	A0A0K2FIM3	Achromobacter_phage	4.5e-05	30.4
AYV50102.1\|380865_381492_+	DUF4479 domain-containing protein	NA	NA	NA	NA
AYV50103.1\|381654_382995_+	NADH oxidase	NA	NA	NA	NA
AYV50104.1\|383084_383474_+	single-stranded DNA-binding protein	A0A0K0MWE1	Streptococcus_phage	1.4e-24	45.0
AYV50105.1\|383593_383878_+	co-chaperone GroES	A0A221S386	uncultured_virus	3.1e-13	44.1
AYV50106.1\|383965_385594_+	molecular chaperone GroEL	A0A219YK78	uncultured_virus	4.9e-156	56.8
AYV50107.1\|385639_386452_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	3.1e-34	38.1
AYV50108.1\|386622_388065_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.4e-32	33.0
AYV50109.1\|388057_388759_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.2e-42	39.7
AYV50110.1\|388936_389572_+	dTMP kinase	M1PSC7	Streptococcus_phage	5.4e-74	65.0
AYV50111.1\|389704_390565_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.0e-67	45.2
AYV50112.1\|390616_391399_+	Signal peptidase	NA	NA	NA	NA
AYV50113.1\|391391_391718_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
AYV50114.1\|391717_392593_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	8.7e-99	65.4

DBSCAN-SWA_3

547995 : 585492

Bacillus_phage(35.71%)

tRNA,integrase,protease,transposase

attL 567319:567378|attR 586014:586125

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV50255.1\|547995_548880_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
AYV50256.1\|548962_549631_+	hypothetical protein	NA	NA	NA	NA
AYV50257.1\|549801_550698_+	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	34.8
AYV50258.1\|551072_551333_+	hypothetical protein	NA	NA	NA	NA
AYV50259.1\|551690_552614_+	ribonuclease Z	NA	NA	NA	NA
AYV50260.1\|552606_553308_+	SDR family oxidoreductase	NA	NA	NA	NA
AYV50261.1\|553474_555703_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.3e-79	30.4
AYV50262.1\|555780_556338_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.6e-32	43.4
AYV50263.1\|556553_557117_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
AYV50264.1\|557253_558906_+	endolytic transglycosylase MltG	NA	NA	NA	NA
AYV50265.1\|558968_559439_+	transcription elongation factor GreA	NA	NA	NA	NA
AYV50266.1\|559557_560705_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-46	41.0
AYV50267.1\|560778_562151_-\|transposase	IS3-like element ISLla3 family transposase	A0A1B1P773	Bacillus_phage	2.3e-53	43.1
AYV51725.1\|562350_562806_+	CtsR family transcriptional regulator	NA	NA	NA	NA
AYV50268.1\|562795_565246_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	5.7e-124	34.0
AYV50269.1\|565380_565938_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
AYV50270.1\|566122_567424_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.0e-217	87.6
567319:567378	attL	NA	NA	NA	NA
AYV50271.1\|567508_568447_+\|integrase	integrase	A0A142F1N9	Bacillus_phage	5.2e-25	27.5
AYV50272.1\|568719_569487_+	hypothetical protein	NA	NA	NA	NA
AYV51726.1\|570074_570215_+	hypothetical protein	NA	NA	NA	NA
AYV50273.1\|570530_570713_+	hypothetical protein	NA	NA	NA	NA
AYV50274.1\|570734_571904_+	hypothetical protein	V9VGE4	Lactococcus_phage	1.1e-37	40.4
AYV50275.1\|573776_576764_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	5.5e-20	26.4
AYV50276.1\|576803_578351_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.4e-99	39.1
AYV50277.1\|578347_579571_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.6e-34	30.7
AYV50278.1\|579591_579717_+	hypothetical protein	NA	NA	NA	NA
AYV50279.1\|579694_580774_+	hypothetical protein	NA	NA	NA	NA
AYV50280.1\|580935_581205_+	hypothetical protein	NA	NA	NA	NA
AYV50281.1\|581506_582618_-\|transposase	IS3-like element IS981 family transposase	A0A1P8CWQ3	Bacillus_phage	1.2e-49	41.4
AYV51727.1\|582766_582934_+	hypothetical protein	NA	NA	NA	NA
AYV50282.1\|583199_583970_+	hypothetical protein	NA	NA	NA	NA
AYV50283.1\|584380_585492_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.2e-50	41.1
586014:586125	attR	NA	NA	NA	NA

DBSCAN-SWA_4

933811 : 947595

Enterococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV50579.1\|933811_934504_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	2.7e-31	34.4
AYV50580.1\|934496_935432_+	ABC transporter permease	NA	NA	NA	NA
AYV50581.1\|935533_936511_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	2.4e-118	66.2
AYV50582.1\|936860_939029_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.0e-257	61.1
AYV50583.1\|939164_939587_-	protein NrdI	A0A142F1R4	Bacillus_phage	2.3e-12	37.3
AYV50584.1\|939588_939807_-	NrdH-redoxin	C3U2K9	Lactococcus_phage	7.6e-12	47.6
AYV50585.1\|939980_940622_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
AYV50586.1\|940896_942831_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.6e-124	43.2
AYV50587.1\|943566_944400_+	3'-5' exonuclease	A0A0K2SUJ2	Clostridium_phage	3.1e-21	39.4
AYV50588.1\|944396_944846_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYV50589.1\|945120_947595_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	4.2e-98	32.2

DBSCAN-SWA_5

956253 : 964521

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV50597.1\|956253_957342_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	8.4e-51	38.8
AYV50598.1\|957341_957992_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-41	43.6
AYV50599.1\|958000_959197_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.3e-110	51.0
AYV50600.1\|959224_959689_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.3e-39	53.0
AYV50601.1\|959791_960244_+	signal peptidase II	NA	NA	NA	NA
AYV50602.1\|960304_961210_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	5.4e-11	28.2
AYV50603.1\|961356_961800_+	divergent PAP2 family protein	NA	NA	NA	NA
AYV50604.1\|961939_963562_+	hypothetical protein	NA	NA	NA	NA
AYV50605.1\|963564_964521_+	glycosyltransferase	I1TED8	Salmonella_phage	3.1e-49	37.5

DBSCAN-SWA_6

1415971 : 1426272

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV50996.1\|1415971_1417528_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.3e-70	45.6
AYV50997.1\|1417703_1418246_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	1.8e-09	29.9
AYV50998.1\|1418382_1419420_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
AYV50999.1\|1419550_1420081_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AYV51000.1\|1420131_1421721_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.0e-09	22.2
AYV51001.1\|1421887_1422436_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.8e-18	31.1
AYV51002.1\|1422463_1423480_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	6.4e-61	40.4
AYV51003.1\|1423668_1426272_-	chaperone protein ClpB	K4FB40	Cronobacter_phage	9.4e-125	32.8

DBSCAN-SWA_7

1628140 : 1637999

Prochlorococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV51183.1\|1628140_1628902_-	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-17	30.5
AYV51184.1\|1629067_1629877_-	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.0e-10	26.5
AYV51185.1\|1629910_1630804_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
AYV51186.1\|1630803_1631727_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
AYV51187.1\|1631847_1632699_-	phosphate ABC transporter substrate-binding protein PstS family protein	E3SNT9	Prochlorococcus_phage	4.2e-05	27.3
AYV51188.1\|1633045_1633942_-	phosphate ABC transporter substrate-binding protein	E3SM63	Prochlorococcus_phage	7.2e-08	32.4
AYV51189.1\|1634219_1634687_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.7e-43	56.6
AYV51190.1\|1634718_1635294_-	esterase	NA	NA	NA	NA
AYV51191.1\|1635380_1637999_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	7.1e-64	33.7

DBSCAN-SWA_8

1925688 : 1990846

unidentified_phage(20.0%)

tRNA,protease,bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV51450.1\|1925688_1926636_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	3.4e-32	33.0
AYV51451.1\|1926656_1926866_-	hypothetical protein	NA	NA	NA	NA
AYV51452.1\|1926901_1927420_-	peptide-methionine (S)-S-oxide reductase	NA	NA	NA	NA
AYV51453.1\|1927594_1928452_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
AYV51454.1\|1928497_1928956_-	N-acetyltransferase	NA	NA	NA	NA
AYV51455.1\|1929048_1929606_-	ribosome recycling factor	NA	NA	NA	NA
AYV51456.1\|1929817_1930534_-	UMP kinase	NA	NA	NA	NA
AYV51457.1\|1930618_1931071_-	hypothetical protein	NA	NA	NA	NA
AYV51458.1\|1931204_1932392_-	acetate kinase	NA	NA	NA	NA
AYV51459.1\|1932548_1933736_-	acetate kinase	NA	NA	NA	NA
AYV51460.1\|1933930_1934869_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AYV51461.1\|1934956_1935208_-	DUF3165 family protein	NA	NA	NA	NA
AYV51462.1\|1935304_1937146_-	translational GTPase TypA	A0A1S5SF82	Streptococcus_phage	1.2e-17	35.4
AYV51463.1\|1937324_1937783_-	hypothetical protein	NA	NA	NA	NA
AYV51464.1\|1937798_1938572_-	hypothetical protein	NA	NA	NA	NA
AYV51465.1\|1938908_1939535_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-19	34.5
AYV51466.1\|1939535_1941518_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
AYV51467.1\|1941521_1941848_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
AYV51468.1\|1942147_1942876_-	LytTR family transcriptional regulator	NA	NA	NA	NA
AYV51469.1\|1943068_1943290_+	DUF910 family protein	NA	NA	NA	NA
AYV51470.1\|1943323_1944295_+	ROK family glucokinase	NA	NA	NA	NA
AYV51471.1\|1944297_1944684_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
AYV51472.1\|1944766_1945213_-	DNA starvation/stationary phase protection protein	A0A2K9VCK5	Lactobacillus_phage	6.5e-18	34.2
AYV51473.1\|1945350_1946462_-\|transposase	IS3-like element IS981 family transposase	A0A1P8CWQ3	Bacillus_phage	1.2e-49	41.4
AYV51474.1\|1946606_1947272_+	prepilin peptidase	NA	NA	NA	NA
AYV51475.1\|1947222_1948314_-	DNA polymerase IV	NA	NA	NA	NA
AYV51476.1\|1948392_1948884_-\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
AYV51477.1\|1948962_1950456_-	amino acid permease	NA	NA	NA	NA
AYV51478.1\|1950647_1951778_-	aminotransferase	NA	NA	NA	NA
AYV51479.1\|1952041_1952986_-	carbamate kinase	NA	NA	NA	NA
AYV51480.1\|1953017_1953962_-	carbamate kinase	NA	NA	NA	NA
AYV51775.1\|1954081_1955554_-	amino acid permease	NA	NA	NA	NA
AYV51481.1\|1955684_1956749_-	ornithine carbamoyltransferase	NA	NA	NA	NA
AYV51482.1\|1956932_1958165_-	arginine deiminase	NA	NA	NA	NA
AYV51483.1\|1958231_1958429_+	hypothetical protein	NA	NA	NA	NA
AYV51484.1\|1958466_1960161_-\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	2.1e-80	34.8
AYV51485.1\|1960228_1960687_+	arginine repressor	NA	NA	NA	NA
AYV51776.1\|1960869_1962201_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
AYV51486.1\|1962403_1962997_-	hypothetical protein	NA	NA	NA	NA
AYV51487.1\|1963212_1966317_-	helicase	A0A2L1IWL4	Gordonia_phage	5.3e-42	30.1
AYV51488.1\|1966570_1970923_-	VWA domain-containing protein	NA	NA	NA	NA
AYV51489.1\|1971345_1973049_-	pyruvate oxidase	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	1.9e-33	27.2
AYV51490.1\|1973245_1974232_-	serine hydrolase	NA	NA	NA	NA
AYV51491.1\|1974304_1975084_-	proteinase	NA	NA	NA	NA
AYV51492.1\|1975437_1976223_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AYV51493.1\|1976265_1977135_-	aquaporin family protein	NA	NA	NA	NA
AYV51494.1\|1977306_1979598_+	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
AYV51495.1\|1979599_1980310_+	gamma-glutamyl-gamma-aminobutyrate hydrolase	H9D1C6	Salinivibrio_phage	5.2e-09	31.8
AYV51496.1\|1980459_1981302_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AYV51497.1\|1982820_1984272_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
AYV51498.1\|1984435_1984966_-	cysteine hydrolase	NA	NA	NA	NA
AYV51499.1\|1985064_1985988_-	phosphatase PAP2 family protein	NA	NA	NA	NA
AYV51500.1\|1986216_1986711_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYV51501.1\|1986802_1987126_-	DUF1048 domain-containing protein	NA	NA	NA	NA
AYV51502.1\|1987112_1987460_-	DUF1048 domain-containing protein	NA	NA	NA	NA
AYV51503.1\|1987446_1987809_-	PadR family transcriptional regulator	NA	NA	NA	NA
AYV51504.1\|1987928_1988558_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
AYV51505.1\|1988622_1989708_-	PIN/TRAM domain-containing protein	NA	NA	NA	NA
AYV51506.1\|1989898_1990846_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	8.9e-33	33.0

DBSCAN-SWA_9

2038754 : 2111152

unidentified_phage(18.18%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYV51568.1\|2038754_2040605_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
AYV51569.1\|2040674_2041961_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
AYV51570.1\|2041979_2042783_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
AYV51571.1\|2042782_2043517_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	5.9e-16	37.0
AYV51572.1\|2043888_2044221_-	preprotein translocase subunit YajC	NA	NA	NA	NA
AYV51573.1\|2045031_2045511_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
AYV51574.1\|2045549_2046497_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	3.4e-32	33.0
AYV51575.1\|2046966_2048193_+\|protease	serine protease	A0A1B1IRD3	uncultured_Mediterranean_phage	4.9e-07	26.3
AYV51576.1\|2048318_2049317_+	glycosyltransferase	NA	NA	NA	NA
AYV51577.1\|2049442_2050783_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
AYV51578.1\|2050890_2051115_+	DUF1797 family protein	NA	NA	NA	NA
AYV51579.1\|2051256_2052261_+	hypothetical protein	NA	NA	NA	NA
AYV51580.1\|2052301_2053054_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
AYV51581.1\|2053400_2056034_-	DNA polymerase I	A0A068EMS7	Bacillus_phage	7.7e-50	31.4
AYV51582.1\|2056271_2057081_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AYV51583.1\|2057570_2058718_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-46	41.0
AYV51584.1\|2058790_2060163_-\|transposase	IS3-like element ISLla3 family transposase	A0A1B1P773	Bacillus_phage	2.4e-55	43.8
AYV51585.1\|2060204_2060738_+	hypothetical protein	NA	NA	NA	NA
AYV51586.1\|2066155_2066647_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AYV51587.1\|2066904_2068635_-	septation ring formation regulator EzrA	NA	NA	NA	NA
AYV51588.1\|2068820_2069849_-	elongation factor Ts	NA	NA	NA	NA
AYV51589.1\|2069970_2070738_-	30S ribosomal protein S2	NA	NA	NA	NA
AYV51590.1\|2071096_2072122_+	hypothetical protein	NA	NA	NA	NA
AYV51591.1\|2072354_2075066_+	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
AYV51592.1\|2075403_2075901_-	hypothetical protein	NA	NA	NA	NA
AYV51593.1\|2075887_2076097_-	hypothetical protein	NA	NA	NA	NA
AYV51594.1\|2076093_2076921_-	radical SAM protein	NA	NA	NA	NA
AYV51595.1\|2076913_2079037_-	radical SAM protein	NA	NA	NA	NA
AYV51596.1\|2079139_2079997_-	transcriptional regulator	A0A1X9I6E0	Streptococcus_phage	2.3e-11	28.7
AYV51597.1\|2080117_2081146_-	PDZ domain-containing protein	NA	NA	NA	NA
AYV51598.1\|2081132_2081630_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	8.9e-16	31.4
AYV51599.1\|2081677_2082244_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
AYV51600.1\|2082387_2083608_-	MFS transporter	NA	NA	NA	NA
AYV51601.1\|2083691_2084918_-	multidrug efflux MFS transporter LmrP	NA	NA	NA	NA
AYV51602.1\|2085105_2085600_+	RNA polymerase sigma factor	NA	NA	NA	NA
AYV51603.1\|2085623_2086730_+	anti-sigma factor	NA	NA	NA	NA
AYV51604.1\|2086825_2088172_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
AYV51605.1\|2088515_2089022_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
AYV51606.1\|2089055_2089901_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AYV51607.1\|2090127_2090406_+	transcriptional regulator	NA	NA	NA	NA
AYV51608.1\|2090518_2090851_+	hypothetical protein	NA	NA	NA	NA
AYV51609.1\|2090894_2093537_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	2.0e-151	41.2
AYV51610.1\|2093792_2094449_-	elongation factor G-binding protein	NA	NA	NA	NA
AYV51611.1\|2094725_2094974_-	DUF1912 family protein	NA	NA	NA	NA
AYV51612.1\|2095012_2095357_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
AYV51613.1\|2095357_2095867_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AYV51614.1\|2096021_2096729_-	hypothetical protein	NA	NA	NA	NA
AYV51615.1\|2097060_2098602_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	E4ZFI6	Streptococcus_phage	1.2e-71	32.7
AYV51616.1\|2098830_2101611_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
AYV51617.1\|2101679_2102153_-	cell wall anchor protein	NA	NA	NA	NA
AYV51618.1\|2102438_2103251_+	regulatory protein RecX	NA	NA	NA	NA
AYV51619.1\|2110204_2111152_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	1.7e-31	32.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP033606

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection