CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Prophage number
CP033756	Klebsiella pneumoniae strain FDAARGOS_566 chromosome 1, complete sequence	3 crisprs	csa3,DEDDh,DinG,cas3,WYL	3	4
CP033757	Klebsiella pneumoniae strain FDAARGOS_566 chromosome 2	0 crisprs	NA	0	0
CP033758	Klebsiella pneumoniae strain FDAARGOS_566 plasmid unnamed2	0 crisprs	TnsE_C	0	2
CP033759	Klebsiella pneumoniae strain FDAARGOS_566 plasmid unnamed3, complete sequence	0 crisprs	NA	0	0
CP033755	Klebsiella pneumoniae strain FDAARGOS_566 plasmid unnamed1, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP033756_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033756_1

470093-470511

Orphan

Consensus_repeat	Method
AAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACG	PILER-CR

3 spacers

The CRISPR arrays of CP033756_1

>merge|CP033756|1|470093-470511|PILER-CR
AAAACAGGCGCCTGGCACCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACGTTTCCGTGACATTTGTCGCAGTTCGTAGGCCCGGTAAGGCGCAGCCGCCACCGGGCAAAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACGTTTCCGTGACATTTGTCGCAGTTCGTAGGCCCGGTAAGGCGCAGCCGCCACCGGGCAAAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACGTTTCCGTGACATTTGTCGCAGTTCGTAGGCCCGGTAAGGCGCAGCCGCCACCGGGCAAAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACG

>CP033756|1|1|470093-470511|PILER-CR
AAAACAGGCGCCTGGCACCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACG	TTTCCGTGACATTTGTCGCAGTTCGTAGGCCCGGTAAGGCGCAGCCGCCACCGGGCA
AAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACG	TTTCCGTGACATTTGTCGCAGTTCGTAGGCCCGGTAAGGCGCAGCCGCCACCGGGCA
AAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACG	TTTCCGTGACATTTGTCGCAGTTCGTAGGCCCGGTAAGGCGCAGCCGCCACCGGGCA
AAAACAGGCGCCTGGCGCCGGATGCCCATTGCCGGGCGGCGCTGCGCTTGCGCCGGCCTACG

Protein	Signature genes	Signature genes Name	Protein_function
CP033756.1\|AYY20261.1\|466578_467400_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
CP033756.1\|AYY20267.1\|475921_477007_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|238527
CP033756.1\|AYY20260.1\|465556_466582_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
CP033756.1\|AYY20268.1\|477151_478045_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP033756.1\|AYY20259.1\|464507_465560_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
CP033756.1\|AYY20257.1\|462641_463544_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
CP033756.1\|AYY20262.1\|467905_469978_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|273805
CP033756.1\|AYY20269.1\|478151_478754_+\|cysteine-dioxygenase	unknown	unknown	gnl\|CDD\|227840
CP033756.1\|AYY20255.1\|460953_461718_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
CP033756.1\|AYY20254.1\|459357_459972_-\|DUF1062-domain-containing-protein	unknown	unknown	gnl\|CDD\|226782
CP033756.1\|AYY20271.1\|480352_481078_-\|laccase-domain-containing-protein	unknown	unknown	gnl\|CDD\|319354
CP033756.1\|AYY20266.1\|473805_474768_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270276
CP033756.1\|AYY20265.1\|472771_473809_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223787
CP033756.1\|AYY24603.1\|474773_475868_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
CP033756.1\|AYY20258.1\|463540_464494_-\|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238566
CP033756.1\|AYY24602.1\|460244_460967_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
CP033756.1\|AYY20264.1\|471795_472791_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223673
CP033756.1\|AYY20270.1\|478759_480340_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|238793
CP033756.1\|AYY20263.1\|471028_471802_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
CP033756.1\|AYY20256.1\|461781_462549_-\|basic-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270342

Protein	Function_ID	Function_description	E-value
CP033756.1\|AYY20261.1\|466578_467400_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	1.00519e-119
CP033756.1\|AYY20267.1\|475921_477007_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|238527	cd01094, Alkanesulfonate_monoxygenase, Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).	1.38999e-92
CP033756.1\|AYY20260.1\|465556_466582_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.0127e-69
CP033756.1\|AYY20268.1\|477151_478045_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	9.4381e-37
CP033756.1\|AYY20259.1\|464507_465560_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	2.10019e-70
CP033756.1\|AYY20257.1\|462641_463544_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.19519e-49
CP033756.1\|AYY20262.1\|467905_469978_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	1.53227e-100
CP033756.1\|AYY20269.1\|478151_478754_+\|cysteine-dioxygenase	gnl\|CDD\|227840	COG5553, COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only].	2.39853e-53
CP033756.1\|AYY20255.1\|460953_461718_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.5599e-78
CP033756.1\|AYY20254.1\|459357_459972_-\|DUF1062-domain-containing-protein	gnl\|CDD\|226782	COG4332, COG4332, Uncharacterized protein conserved in bacteria [Function unknown].	8.71819e-73
CP033756.1\|AYY20271.1\|480352_481078_-\|laccase-domain-containing-protein	gnl\|CDD\|319354	cd16833, YfiH, protein of unknown function YfiH. This subfamily contains YfiH, a protein of unknown function from Shigella flexneri, E. coli, and many similar proteins which collectively are often called DUF152. The structure of YfiH reveals a distant homology to Rho-activating toxins cytotoxic necrotizing factor 1 (CNF1) as well as chemotaxis protein CheD that stimulates methylation of methyl-accepting chemotaxis proteins (MCPs), all having an invariant Cys-His pair forming a catalytic dyad, and is required by the CNF-1 toxins for deamidation activity.	2.06622e-49
CP033756.1\|AYY20266.1\|473805_474768_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270276	cd13558, PBP2_SsuA_like_2, Putative substrate binding domain of sulfonate binding protein, the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.47757e-105
CP033756.1\|AYY20265.1\|472771_473809_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	3.58061e-27
CP033756.1\|AYY24603.1\|474773_475868_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	7.84065e-51
CP033756.1\|AYY20258.1\|463540_464494_-\|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	1.13925e-42
CP033756.1\|AYY24602.1\|460244_460967_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.15111e-152
CP033756.1\|AYY20264.1\|471795_472791_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.36619e-38
CP033756.1\|AYY20270.1\|478759_480340_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|238793	cd01535, 4RHOD_Repeat_4, Member of the Rhodanese Homology Domain superfamily, repeat 4. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 4th repeat which, in general, contains the putative catalytic Cys residue.	2.31451e-65
CP033756.1\|AYY20263.1\|471028_471802_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.04308e-109
CP033756.1\|AYY20256.1\|461781_462549_-\|basic-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270342	cd13624, PBP2_Arg_Lys_His, Substrate binding domain of the arginine-, lysine-, histidine-binding protein ArtJ; the type 2 periplasmic binding protein fold. This group includes the periplasmic substrate-binding protein ArtJ of the ATP-binding cassette (ABC) transport system from the thermophilic bacterium Geobacillus stearothermophilus, which is specific for arginine, lysine, and histidine. ArtJ belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.97659e-96

>CP033756.1|AYY20262.1|467905_469978_+|TonB-dependent-siderophore-receptor
MAADNRAAKSTNDAEETITVVADGAQQSATSGYQPLSSATATLTSMPLLDIPQVVNTVSDRVLEDQHATSLDEALYNVANVVQTNTLGGTQDAFTRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTLYGILDPGGLINVITKRPERQFSGSVSGTSTSFGGGTGSVDITGPIEGTNLAYRLIGEYQNEDYWRNFGKNKSSFIAPSLTWFGERATVTASYSHRDYSAPFDRGTIFDLNTGHAVNVDRKTRFDEAFNITDGYSDLAQLNAEYRLNDAWTARFDYSYSQDHYNDNQARVMAYDSATGNLTRRVDGTHGSTQKMHSTRADLQGNVVVGGFYNELLTGVAYENYDLLRTDMLRCKNVKGFNIYHPVYGTLDTCNTVSASDSDQRIQQESYAAYVQDALYLTDNWIAVAGVRYQYYTQYAGKGRPFNVNTDSRDEKWTPKAGLVYKVTPNVSLFANVAQSFMPQSSIASYIGELPPEESTSYEVGAKFDLLNGITANIALFDIHKRNVLYTESIGDETVAKTAGKVRSQGVEVDLAGSITDNLSVIASYGYTDAKVLEDPDYAGKPLPNVPKHTGSLFLTYDIHNVYNSNTLTVGGGGHAVSKRSGTNGADYYLQGYAVADVFAAYKMKLQYPVTLQVNVKNLFDKTYYTSSIGTNNLGNQIGDPREVQFTVKMDF
>CP033756.1|AYY20261.1|466578_467400_-|ABC-transporter-ATP-binding-protein
MPQRVKPAEQGIVLDALSAGYGQTLIVDDINLTIPTGKMTVLAGANGSGKSTLLSTIARMLKPLGGCVRLDGQAIHQMPTKTVSRQLGILPQSPLTPEGLTVFELVSRGRYPWQGLMRQWSEADELAVEEALRLTGTAEFAHLPVDSLSGGQRQRCWIAMALAQQTATILLDEPTTWLDLRYQVDILELLQTLTREHGRTVVTVLHDLNFAVNYADLLVFLKQGRIAGTISDNDVCSPELIKRVFDVDVQMSINPQTGKPFFMPFRARQAAAQ
>CP033756.1|AYY20260.1|465556_466582_-|iron-ABC-transporter-permease
MSVAILLSARRRPRPRLALLLLTLLLIAASLVHLGLGARWIAPQTVLRALLEYDPRNFEQRIIIDLRLVRLAAALLTGAALGVAGLLLQTVIRNPLGEPHILGLNAGASLAVVATSALGLSLGAFPVGRPLTAACGAGLLFGGVMALASAGRGGATPLRITLCGVALSGFASAVTAAILILDEQTLLAMRTWLAGDLAGLNWSTLQTALVPALIGLGVALLIAPRLNVLALGDKVALGLGVNLVQTRLLGLLAIALLCGAAVAVAGPIGFVGLVVPHVVRRLVTEDIRLALPLAAPVGALALVLADIAARTLVAPQELATGAMTALVGAPLFIFIAARFFK
>CP033756.1|AYY20259.1|464507_465560_-|iron-ABC-transporter-permease
MTRAVHRAGFRPQAFASRQLLLRPAALKIAASIVLTLLALGLYSLSRGSYPLPASTLARALLAPQEMGEQPRFILFDIRLPRILMALLCGAMLGLAGAAMQSITRNGLADPGLIGVKEGASIVVLALVLFFPAVGLVWRPLAGMVGGIAVALLVLTLARDCSRPRFILIGIGVSWTLAAAVGIFMTTADVRDVQTAMIWLAGSLQAATWPLLAVAFCWALPGAIILFCTARAADVALLGDRTAIGLGVRLQQLTVLRFFAPVLLTSASVSCVGSLGFVGLMAPHMARFVLRGGQVSLLCGSALIGALLVLATDTLGRLAFAPLQIPAGIVIALVGCPFFVVLLWRRRDAL
>CP033756.1|AYY20258.1|463540_464494_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MRWFVSLLLLLTGAVSAAAPQTQTFTDDLGRTVTVPLHPQRIVSMHDLDITIPLIELGAPPIASHGRTRPDGSHYLRSSAQLTGVDFDNSDIRFIGTADIDLEAVAAARPDLIITEPSRHVSVEQLEKIAPTVSIDHLQGSAPEIYRKLAQLTATQPRLAILERRYQEQIKQLKAMVNPPQYSVSVIQANNGKVTVHHSYHALGRVLRDAGFRFPPLIERIPDGQRIDVSAEQLPELDADFVFATWRSDTGGKPQDELQAMEGVMPGWCDFMRACRTGHYILLPREEVISNSYAALSLMVAQVQSHIAGRPIPAEAK
>CP033756.1|AYY20257.1|462641_463544_-|MurR/RpiR-family-transcriptional-regulator
MKSAVKKEKGKVDLFGERYRARAHQLSPRLRAVVSYINDNREVVLEHTAMEIATATQTSDATVVRAIQALGFAGLRELKQTMERWFGTSVTSAEKMRSTVTALSSDVNSSIDFVLEGHQRVCEVLSRADNRAAVAQAVALLSDARQVGIFGIGASGILAEYTARLFSRIGLPAYVMNRTGFSLAEQLIGLQRGDVLIMMGQKSPHREGLTTLREAKRLGIPTILLTQAVDSRFSQEAQVVIDVPRGGDSSRMPLHGTVLVCLEMIVLSVASTTPQKTVKSLKRINDLHRAIGKSGGKRGH
>CP033756.1|AYY20256.1|461781_462549_-|basic-amino-acid-ABC-transporter-substrate-binding-protein
MVKNLLKACCMIAALTAAGQAAAETYTVGSGGTYRPFEFENSQKQLEGFDIDIIKAIAKAEGFDVKLVNTPWEGIFATLNTGDRDIIISGITITDKRKQMVDFSAPYFPAEQSIVVAQDSQVDSLAALKNEKVGVVNSSTGDIVVSEVLGKNSTAIKRFDNTPLMLQELFEDGVSAAVGDVGVVKYYIKQHPEKQFKLVPDAKFERQYFGIAVAKGNSELLGKINAGLQKIVADGTYAKIYKTWFDDNVPTLPAQ
>CP033756.1|AYY20255.1|460953_461718_-|amino-acid-ABC-transporter-permease
MTGFRWEIIEEYGPLFVDGALMTIKCTIICVILGTLWGLTLGLGRMAKAEHGPWKYILRYLVQFPVRFYVSAFRGTPLFVQIMVVHFALVPLFINPRDGLLVTSGLMSADFARELRASYGAFLSCIVAITLNAGAYVSEIFRAGIQSIDKGQMEASRALGMPWWKTMRKVILPQAFRRILPPLGNNAIAIVKDSSLASAIGLADLAYAARTVSGAYATYWEPYLTISLVYWVITFLLAQLVNRLEKRFGKSDSH
>CP033756.1|AYY24602.1|460244_460967_-|amino-acid-ABC-transporter-ATP-binding-protein
MIHINNLHKRFGDSHVLRGISCDIKPQEVVCIIGPSGSGKSTFLRCMNALETVSEGEVVVNGFAAHDRTTDLNKMRESVGMVFQRFNLFPHMTVLENLIMAPMNLRNMPRQQAVDLAEALLAKVGLSDKRDAWPSSLSGGQQQRVAIARALAMKPSIMLFDEPTSALDPELVGDVLEVMKNLASEGMTMVIVTHEMGFAREVADRVIFIDQGVIQEEGKPGQIFSAPSNPRTAAFLSKVL
>CP033756.1|AYY20254.1|459357_459972_-|DUF1062-domain-containing-protein
MTVTWTVTPVGYQHIAKRCPACNVKRDFAPSGAIRVNSQKKLLDIWSIYKCTHCDYTWNIALFSRLHVSKINRELLQRLLQNDAAMVHYYAADLATLKRNRAEPSGQPDFRIHEQWSVTLMTCQRITVRVRVSQPFRISLLSILKKQLKLSTAEIRWLVATGHIEGIPLKQLKTKKLKAMEYDFQLAAETLYARRRITLSLCGR
>CP033756.1|AYY20263.1|471028_471802_-|ABC-transporter-ATP-binding-protein
MVTETIARGAAVSISHLHHAFTLGKQTVPVLENISLQLRPGESVALLGPSGCGKSTLLRLLAGLEAPQSGQMQIDGAALGAPGPERILVFQDPTLYPWLTVRQNVLLGPQAQGKKGLEAKADALIDRIGLQAFSEAWPRQLSGGMAQRAALARALLNEPRLLLLDEPLGKLDSLTRISMQRELIALWQQQGYTSLLVTHDIEEALLLCERVLVMSPRPGRIIAEFALPLAFPRHRDNPQLLQHRQDILRILGQEADW
>CP033756.1|AYY20264.1|471795_472791_-|ABC-transporter-permease-subunit
MPTYSPEQALARPTGRAPLWGEGLLAATLWLLGGLFTLTWPDAGRRWPFSEGWALAQFTLGGGLLLLALSYRYWRARGARVLHAGKWLALLPVLFAVWEGLTAKTAVLPVPFFAPPQALIEVLHDDWPRLLDSLLHSLGLLGLGVLLGTSSGFITGLAIGWSQRIGYWVHPVLRLLGPVPSTALLPLCLFIFPSSFGASVFLIALSTWFPVTVLTWSGVMGIDKAWYDVARTLGASQRFLILRVAIPAALPNVFVGLFMGLGASFSVLIVAEMVGVKSGIGFYLQWAQGWAAYPNMYAALLVMALLCSGLISGLFMLRDRLLSWQRGGMQW
>CP033756.1|AYY20265.1|472771_473809_-|ABC-transporter-substrate-binding-protein
MTRTPFSRRRFLQLSGGLALAGVSLPLWAHDMADMAGGDTHPALRLPQPYKIKLAINKSAVCLAPVAVAEQQKIFSKYNLDVEFVNFGNSTDVLLEAIATGKADAGVGMALRWLKALEQGFDVKLTAGTHGGCLNLLTAKDSPFGGLESLKGQTIGVTDMAGPDKNFFAILLKRHGIDPIGDVQWKVYPADLLSVALDKREIAAISGSEPFSYRLLETGKYQLIASNMTGDYANLSCCVLGVSGSLARDHKPAAAALTQAILEAHSYAAAHPESVAQSFLAHALNTSEAEVSGILHGQGHGHHAVGEAFVKELTQYAVDLQRVQVIKPGTDPHQFAESIYANVFA
>CP033756.1|AYY20266.1|473805_474768_-|ABC-transporter-substrate-binding-protein
MRLSFSGRVAAALMLLALGGYATAQERLTLRIADQKGGMRSQLEAANALQNLPYDIKWAEFPAAAPLAEALNAGAVDAGIIGDAPLLFALANGAPVKAIAVDKSNPAGTAVLVSPGSTLKSGADLKGKRIATGKGSIGHFVALKALEQAGISPKEVQWVFLGPVDAKVALLNGSVDAWATWEPYTTQMVKTNEGQILVSGKGLLPGNTFLAATDSALNDPQKRAALQDYLQRLAGAERWAYANLDSYGKTLGEIIRFPAEIARAQFANRQSQWQPLAEETVAQQQATADFYLANGLIRTRLDVKPTFDRRFSVPAAEVTP
>CP033756.1|AYY24603.1|474773_475868_-|acyl-CoA-dehydrogenase
MAEQAASLDASGEFPWRNIDHLRAGGWLSLAVPPSCGGAGASLAQLQQVIAAIAWGEPATALIVCMQYLHHLRLAENDAWHAPLRQQVFHDAVEHGGLINSLRVEPELGSPARGGLPDTVATRRAEGWDISGHKIYTTGIEGLRWLAVWARSDDNPPLVGTWLVPGDSPGITVVKSWDHAGMRATGSHEVIFNHVRVAAEHAVDVWPADAPPAAQAEPFRLFANRQTALLAAIYDSIAHAAHDWLVRWLAGRVPAGLGHPLSRLPRVQEKVGQIAGLLLVNRSLLEQAAALRFSAIEANLAKVTITDNAIQAVNIALELTGNHGLSRQNPLERHYRNVLCGRVHTPQSDSAWLAAGNFVFQSQG
>CP033756.1|AYY20267.1|475921_477007_-|LLM-class-flavin-dependent-oxidoreductase
MSIQFLGMIGHRLSSETIAPVGPIFDRDYIVRFAQTHEAAGFDRLLVGHWSDQPDGFLVTALAGLSTQKIQYLLAHRPGFVSPTLAARKFATLEHLLEGRLAVHIISGGNDAEQRRDGDYLDHDQRYARTDAFLDIVRQVWTSEQPVDIHNDFYQAEQAWSAIRPLQKPHLPIYFGGSSEAAIAVAGKHADVFALWGESLAQTGETIQRVRAEAAKHQRDIGFSVSFRPIIADSEAEAWEKAEHILHVATEQAAQRGGGFKAKPDSIGAQRLRATAAQGRVVDKRLWTGIAQLVGGGHNSTALVGTPEQVADALLDYYDLGVRNFLIRGFDPLNDAADYGRALLPIAREKAARRAVAERAS
>CP033756.1|AYY20268.1|477151_478045_-|LysR-family-transcriptional-regulator
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAAGHRVYEQCLSIKRETKKLYSLLDPQGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLSPQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGRLLCPLEVVPIAGRRLNLRASSLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVPRAALASSPWRDEIAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD
>CP033756.1|AYY20269.1|478151_478754_+|cysteine-dioxygenase
MTAPRLEKLRHFIHEVDRLHREHHQAAPLLDAVAQRLAALVRYDDWLPEEYTLPHPHHYQQYLLHADSGERFSIVSFVWGPGQATPIHDHRVWGAIGMLRGAEENQRYQLDADGIPRALGAATLLEAGQVEKVSADDGDIHRVSNALADRVSISIHVYGGNIGAVKRAVYTPEGQQKPFISGYSNRHLPNIWDSSREHQG
>CP033756.1|AYY20270.1|478759_480340_+|rhodanese-related-sulfurtransferase
MSTYAYRQAAGIRQALLDRRELALIDVREEADFATAHPLFAVNLPLSKLELEVRRRIPRFTTPLTVYDNGEGLAEIAVERLRSWGYQDVALLAEGLAGWRRSGGELFQDVNSASKAFGELVESVRHTPSLSAQEVQALIDSRQEVVIVDARRFDEYQTMSIPGSISVPGGELALRVESLTPSPQTPVIVNCAGRTRSIIGTQSLINAGVPNPVHALRNGTIGWTLAGQTLAHQQQRQYDPSARASGARAAEVAHLAERAGVAVIDEATLQRWLQQSDRTTFLFDVRSPEEYAAGHYPGSLSAPGGQLVQETDHFASVRGARIVLLDDDGIRAAITGSWLAQMGWETARLSALSTSQLSERGVPAAEVPPGPQAEEISPTQLAQQLEEPGTVVLDFTTSANFVARHIPGAWWLTRSQLRQALEAIPPAQRYVVTCGSSLLARYAVPEVAALTGKPVQLLTGGTLAWIAAGLPLAHGDSGLAVERRDRYRRPYEGTDNSAEAMQAYLEWEYGLVDQLARDGTHGFRVL
>CP033756.1|AYY20271.1|480352_481078_-|laccase-domain-containing-protein
MAYTSRLLNAIPGIRHAFLNVHETAAFPYAELAPVKLVHGNEVHHYQQPLPTRPHADAVFTAVAGQKVGVVTADCLPLLIASRDGRYVCSVHAGWQGLVSGIVDNSLACFRQQGVALADLVIAVGPYIHPCCYEVSAGFYQQLLDQPGGDRVARHRQRLFHSRSGPVSDPLKAAARGSDNLWFDLRAFAEAIFAEAGVAPASVEWLGSCTYCTPQSLGSYRRRTHFPAPKSFQYSWIMREA

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Crispr_ID: CP033756_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033756_2

580044-580145

Orphan

Consensus_repeat	Method
CTGCTGTCTCATCGCTCGCGCTTCGCTTAGCGAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033756_2

>merge|CP033756|2|580044-580145|CRISPRCasFinder
CTGCTGTCTCATCGCTCGCGCTTCGCTTAGCGAGGCTACACATTCCTGCACTCTCAGCCACCTGTTCTGCTGTCTCATCGCTCGCGCTTCGCTTAGCGAGGC

>CP033756|2|1|580044-580145|CRISPRCasFinder
CTGCTGTCTCATCGCTCGCGCTTCGCTTAGCGAGGC	TACACATTCCTGCACTCTCAGCCACCTGTT
CTGCTGTCTCATCGCTCGCGCTTCGCTTAGCGAGGC

Protein	Signature genes	Signature genes Name	Protein_function
CP033756.1\|AYY24607.1\|572857_573475_-\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
CP033756.1\|AYY20364.1\|580753_581650_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
CP033756.1\|AYY20359.1\|575665_576679_-\|two-component-system-response-regulator-RssB	unknown	unknown	gnl\|CDD\|182652
CP033756.1\|AYY20370.1\|590410_592189_+\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX	unknown	unknown	gnl\|CDD\|182581
CP033756.1\|AYY20367.1\|583030_584566_-\|nitrate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|224063
CP033756.1\|AYY20356.1\|570034_572710_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
CP033756.1\|AYY20372.1\|592846_594229_-\|YchO-family-inverse-autotransporter-domain-containing-protein	unknown	unknown	gnl\|CDD\|236661
CP033756.1\|AYY20368.1\|584562_588306_-\|nitrate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|227346
CP033756.1\|AYY20354.1\|568910_569558_-\|YchE-family-NAAT-transporter	unknown	unknown	gnl\|CDD\|236850
CP033756.1\|AYY20366.1\|582323_583034_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl\|CDD\|185014
CP033756.1\|AYY20369.1\|588711_590100_-\|NarK-family-nitrate/nitrite-MFS-transporter	unknown	unknown	gnl\|CDD\|184994
CP033756.1\|AYY20358.1\|574565_575468_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|184021
CP033756.1\|AYY20362.1\|578284_579127_+\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
CP033756.1\|AYY20363.1\|580202_580646_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
CP033756.1\|AYY20361.1\|577783_578242_+\|YchJ-family-protein	unknown	unknown	gnl\|CDD\|234966
CP033756.1\|AYY20365.1\|581646_582324_-\|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl\|CDD\|273030
CP033756.1\|AYY20371.1\|592199_592850_+\|two-component-system-response-regulator-NarL	unknown	unknown	gnl\|CDD\|182619
CP033756.1\|AYY20355.1\|569741_569957_-\|hypothetical-protein	unknown	unknown	unknown
CP033756.1\|AYY20360.1\|576768_577671_-\|patatin-like-phospholipase-RssA	unknown	unknown	gnl\|CDD\|182352
CP033756.1\|AYY20357.1\|574036_574444_+\|DNA-binding-transcriptional-regulator-H-NS	unknown	unknown	gnl\|CDD\|182858

Protein	Function_ID	Function_description	E-value
CP033756.1\|AYY24607.1\|572857_573475_-\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	2.20368e-117
CP033756.1\|AYY20364.1\|580753_581650_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	8.52737e-16
CP033756.1\|AYY20359.1\|575665_576679_-\|two-component-system-response-regulator-RssB	gnl\|CDD\|182652	PRK10693, PRK10693, two-component system response regulator RssB.	0
CP033756.1\|AYY20370.1\|590410_592189_+\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX	gnl\|CDD\|182581	PRK10600, PRK10600, nitrate/nitrite two-component system sensor histidine kinase NarX.	0
CP033756.1\|AYY20367.1\|583030_584566_-\|nitrate-reductase-subunit-beta	gnl\|CDD\|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
CP033756.1\|AYY20356.1\|570034_572710_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
CP033756.1\|AYY20372.1\|592846_594229_-\|YchO-family-inverse-autotransporter-domain-containing-protein	gnl\|CDD\|236661	PRK10177, PRK10177, YchO/YchP family invasin.	0
CP033756.1\|AYY20368.1\|584562_588306_-\|nitrate-reductase-subunit-alpha	gnl\|CDD\|227346	COG5013, NarG, Nitrate reductase alpha subunit [Energy production and conversion].	0
CP033756.1\|AYY20354.1\|568910_569558_-\|YchE-family-NAAT-transporter	gnl\|CDD\|236850	PRK11111, PRK11111, YchE family NAAT transporter.	5.03226e-138
CP033756.1\|AYY20369.1\|588711_590100_-\|NarK-family-nitrate/nitrite-MFS-transporter	gnl\|CDD\|184994	PRK15034, PRK15034, nitrate/nitrite transport protein NarU; Provisional.	0
CP033756.1\|AYY20358.1\|574565_575468_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|184021	PRK13389, PRK13389, UTP--glucose-1-phosphate uridylyltransferase GalU.	0
CP033756.1\|AYY20362.1\|578284_579127_+\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	4.09997e-176
CP033756.1\|AYY20363.1\|580202_580646_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.05574e-32
CP033756.1\|AYY20361.1\|577783_578242_+\|YchJ-family-protein	gnl\|CDD\|234966	PRK01617, PRK01617, hypothetical protein; Provisional.	7.51559e-107
CP033756.1\|AYY20365.1\|581646_582324_-\|respiratory-nitrate-reductase-subunit-gamma	gnl\|CDD\|273030	TIGR00351, Respiratory_nitrate_reductase_2_gamma_chain., respiratory nitrate reductase, gamma subunit. Involved in anerobic respiration the gene product catalyzes the reaction (reduced acceptor + NO3- = Acceptor + nitrite). Another possible role_id for this gene product is in nitrogen fixation (Role_id:160). [Energy metabolism, Anaerobic].	2.8765e-130
CP033756.1\|AYY20371.1\|592199_592850_+\|two-component-system-response-regulator-NarL	gnl\|CDD\|182619	PRK10651, PRK10651, transcriptional regulator NarL; Provisional.	1.26442e-140
CP033756.1\|AYY20366.1\|582323_583034_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl\|CDD\|185014	PRK15054, PRK15054, nitrate reductase molybdenum cofactor assembly chaperone.	1.14838e-83
CP033756.1\|AYY20360.1\|576768_577671_-\|patatin-like-phospholipase-RssA	gnl\|CDD\|182352	PRK10279, PRK10279, patatin-like phospholipase RssA.	0
CP033756.1\|AYY20357.1\|574036_574444_+\|DNA-binding-transcriptional-regulator-H-NS	gnl\|CDD\|182858	PRK10947, PRK10947, DNA-binding transcriptional regulator H-NS.	2.61324e-79

>CP033756.1|AYY20362.1|578284_579127_+|formyltetrahydrofolate-deformylase
MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDATLLADLDSALPEGSIRELNPAGRRRVVILVTKEAHCLGDLLMKANYGGLDVDIAAVIGNHDTLRSLVERFGIPFELVSHEGLSREEHDQRMGDAIAAHEPDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYQVLAQRVFVYGNRTIIL
>CP033756.1|AYY20361.1|577783_578242_+|YchJ-family-protein
MSQLCPCGSALEYSSCCQRYLSGAELAPGPSQLMRSRYSAFVMKDADYLIKTWHPSCQAQQFRAELEKGFSQTEWLGLTLFASDEGRAPNEGFVSFVARFNDNNRPGAIIERSRFLKENGQWYYIDGTRPLIGRNDPCPCGSGKKFKKCCGQ
>CP033756.1|AYY20360.1|576768_577671_-|patatin-like-phospholipase-RssA
MRKLKIGLALGAGAARGWSHIGVINALQRAGIEIDIVAGCSIGSLVGAAYACNRLPALESWVCSFSNWDVLKLMDLSWRRGGLLRGEKVFNHYRRIMPVTEIERCERRFAAVATNLSTGRELWFTEGDLHLAIRASCSMPGLMSPVRHNGYWLVDGAVVNPVPVSLTRAMGADIVIAVDLQHDAHLMQQDLFSLETPRQEAEEKEGPWHTRLRARLTRMSSRRTAVTPTAMEIMTTSIQVLENRLKRNRMAGDPPDILLQPYCPQVSTLDFHRAGEAIAAGQLAVEKKMDELLPLVRTAV
>CP033756.1|AYY20359.1|575665_576679_-|two-component-system-response-regulator-RssB
MTQPLAGKQILIVEDEPVFRSLLHGWLTSLGATTFQAEDGKDALHKMTEVHPDLMICDISMPRMNGLELVETLRNRGEQLPILMISATENMADIAKALRLGVQDVLLKPVKDFDRLRETVYACLYPAMFSSRVEEEERLFEDWDALVSNPIAASRLLQELQPPVQQEMSHCRIHYRQLVSADKPGLVLDIAPLSENDLAFYCLDVTRAGDNGVLAALLLRALFNGLLQEQLAHQGQRLPEMGSLLKQVNQLLRQANLPGQFPLLVGYYHSGLKNLILVSAGLNGTLNTGEHQIQISNGVPLGTLGDAYLNQISQRCTSWQCQIWGAGGRLRLMLSAE
>CP033756.1|AYY20358.1|574565_575468_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MAALNSKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLEEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSRDNLAEMISRFDETGASQIMVEPVEDVTAYGVVDCKGESLKPGESVPMVGVVEKPKADVAPSNLAVVGRYVLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHKTLGDDFKAWLETAVAK
>CP033756.1|AYY20357.1|574036_574444_+|DNA-binding-transcriptional-regulator-H-NS
MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEENAAAAEIEERTRKLQQYREMLIADGIDPNELLSTMAAVKAGTKTKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLI
>CP033756.1|AYY24607.1|572857_573475_-|thymidine-kinase
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLYNPQTSLFDDIAAEHQLKPIHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDFRGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQVVIGGNERYVSVCRKHYKEALSVGSLTKVQNQHRTC
>CP033756.1|AYY20356.1|570034_572710_+|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAVTNIAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKEATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGALNAAIVGQPAAKIAELAGFTVPATTKILIGEVTNVDESEPFAHEKLSPTLAMYRAKDFEDAVAKAEKLVAMGGIGHTSCLYTDQDNQPARVAYFGQMMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLTIVRKGADLANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMVAITTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHALEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLESIKAELGIPKSIREAGVQEADFLAHVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGREFVEGEAGAKAEVAPVKAEKKAKKSA
>CP033756.1|AYY20355.1|569741_569957_-|hypothetical-protein
MHVNVYVEKSGRCFTDLLKKLYLFRFQVLLPSTLLVSSRLLTSEYKLRDLDQVLSLLIPFSWLLFDRFDQV
>CP033756.1|AYY20354.1|568910_569558_-|YchE-family-NAAT-transporter
MTQSLFDFSAYFKFFIGLFALVNPVGIIPVFISMTSYQPAAVRNKTNLTANLSVAIILLTSLFLGDGILQIFGISIDSFRIAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSWVHLVGFSLAIAVFALCCWGIFRMAPWLVRLLGQTGINVITRIMGLLLMALGIEFIVTGIKALFPGLLS
>CP033756.1|AYY20363.1|580202_580646_-|Lrp/AsnC-family-transcriptional-regulator
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNLAALGYSLQALVRVRPLPGLLQKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTLLDGLAEYAQCNTSVVKSSPVKRRLPPL
>CP033756.1|AYY20364.1|580753_581650_+|DMT-family-transporter
MQLTRGVWQMSLAMIISGSIGAFVLLSGLPVADVVFWRCLIGALTLLVFIVLSRQPFSRLTRFTLALAVIGGAALVVNWLLLFAAYSRISIGMATVVYNTQPFMLVLMGMVLGERVSAVKWGWLLLAFGGVVILLSSELTPAHEEGLTTGVLLALGAAFFYALTAIIARKLHPLPAQHIAFIQVLVGVVMLLPLVHAPELTASFPWRYLLILGIVHTGIMYQLLYSAIQKLPTPVTGSLSFIYPLVAMVVDYLVFHHALSAVQLLGGMLILFAAAGNNLGWGEKKPRRGGVSEQSRAS
>CP033756.1|AYY20365.1|581646_582324_-|respiratory-nitrate-reductase-subunit-gamma
MHFLNMFFFDIYPYIAGSVFLIGSWLRYDYGQYTWRAASSQMLDRKGMNLASNLFHIGILGIFAGHFLGMLTPHWMYESFLPIDVKQKMAMIAGGACGVMTLVGGLLLLKRRLLSPRVRATTTGADILILSLLMVQCALGLLTIPFSAQHMDGSEMMKLVGWAQSVVTFHGGASQHLDGVAFIFRVHLVLGMTLFLLFPFSRLVHIWSAPVEYLTRKYQIVRARR
>CP033756.1|AYY20366.1|582323_583034_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MIELVIVSRLLEYPDAALWQHQQEMFEALASSEKLSKEDAHALGVFLRDLVAQDPLDAQAAYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLMAQYERHGLLLDSHELPDHLPLYLEYLAQLPEEEALGGLRDVAPILGLLSARLQQRESRYAVLFELLLKLANTQVDSQKVAEKIADEARDDTPQALDAVWEEEQVKFFADQGCGESEISAHQRRFAGAVAPQYLNISNGGQQ
>CP033756.1|AYY20367.1|583030_584566_-|nitrate-reductase-subunit-beta
MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGMEYAWFNNVESKPGVGFPNDWENQEKWKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYEPFDYDYQNLHNAPESKHQPIARPRSLITGQRMDKITSGPNWEEILGGEFEKRAKDQNFDNMQKAMYGQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIESGMPTVCSETCVGRIRYLGVLLYDADAIENAASTENEKDLYQRQLDVFLDPNDPKVIEQALKDGVPQGVIEAAQQSPVYKMAMDWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLANLLTAGDTQPVLLALKRMLAMRHYKRAETVDGVVDTRALEEVGLSEAQAQEMYRYLAIANYEDRFVVPSSHREQAREAFPEKNGCGFSFGDGCHGSDSQFNLFNSRRIDAIDVTSKTEPHA
>CP033756.1|AYY20368.1|584562_588306_-|nitrate-reductase-subunit-alpha
MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPLMRKRLMKMWREAKVQHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAITPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDKPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRTLRASDLVDSLGQENNPEWKTVAFDEKGDMTVPNGSLGFRWGDKGKWNLEQRDGKTGEEIELRLSLLGSHDEVANVGFPYFGGEGSEHFNKVDLENILLHKLPAKRLQLADGSTALVTTVYDLTMANYGLERGLNDDNCAAGYDEVKAYTPAWAEKITGVSRAHIIRTAREFADNADKTHGRSMIIVGAGLNHWFHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAQELLSPMADKSRYSGHLIDFNVRAERMGWLPSAPQLGVNPLRIADEAKKAGMTPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEYMLKYLLGTENGIQGKDLGKQGGVKPEEVEWRDNGLDGKLDLVVTLDFRLSSTCLYSDIVLPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWESKSDWEIYKGIAKKFSEVCVGHLGKETDVVTLPIQHDSAAEMAQPLDVKDWKKGECDLIPGKTAPHIIPVERDYPATYERFTSIGPLLETIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPKLETAIDAAEMILTLAPETNGQVAVKAWQALSEITGREHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLTGRQSLYQDHQWMRDFGESLLVYRPPIDTRSVKAVMGEKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLSRGGPIVWMSEADAKDLGIEDNDWIEVFNANGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITGQRGGIHNSVTRITPKPTHMIGGYGHLAYGFNYYGTVGSNRDEFVVVRKMKNINWLDGEGNDQVQESVK
>CP033756.1|AYY20369.1|588711_590100_-|NarK-family-nitrate/nitrite-MFS-transporter
MSQSSLPEKANRSVITDWRPEDPEFWQQRGHRVASRNLWISVPCLLLAFCVWMLFSAVAVNLNKVGFQFTTDQLFMLTALPALSGALLRVPYAFMVPLFGGRRWTAFSTGIMIVPCVWLGFAVQDTSTPFSIFVIISLLCGFAGANFASSMANISFFFPKAKQGGALGVNGGLGNMGVSVMQLVAPLVVSISIFAVFGGNGSEQPDGSMLYLENAAWIWVPFLIIFTLAAWFFMNDLSASKASLSEQLPVLKRLHLWIMALLYLATFGSFIGFSAGFAMLSKTQFPDVQILHYAFFGPFIGALARSMGGAISDRLGGTRVTLVNFVVMAVFCALLFLTLPTNGQGGNFIAFFAVFMVLFLTAGLGSASTFQMISVIFRKLTMDRVKAQGGSEAQAMREAATDTAAALGFISAIGAIGGFFIPKAFGISLDLTGSPAGAMKVFLVFYIACVVITWAVYGRKRQ
>CP033756.1|AYY20370.1|590410_592189_+|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX
MLKRLFTPLTLVNQLALIVLLATVIGVAGMAISARLVNGVQGSAHAINKAGSLRMQSYRLLAAIPLNENDQKLVADMTATVFSPELQNSARRDGQEIQLKALQQYWQLALAPGMQRAVNQAEVAQDVADFVDRIDQLVTAFDHTTEQRIERVVWIHRILAIGMALLLIFTIIWLRARLLRPWKQLLSMARAVSQRDFTQRAHISGRNEMATLGMALNNMSEELAESYAVLERRVQEKTAGLEQKNEILAFLWQANRRLHSSAPLCERISPVLNGLQGLTLLRDIEVRVYDLEDEDNHQEFTCHSDDDCDDKGCYLCPRNLPPLPDGGTTLKWRLSDAHSQYGILLATLPVGRHLSHDQQQLVDTLVEQLTSTLALDRHQEKQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPTESRQLLGQIRNELNTSWAQLRELLTTFRLQLTEPGLRPALEASCQEYSAHFGFTVQLDYQLPPRFVPSHQAIHLLQIAREALSNALKHASATEVTVTVSQRDNQVRLVVADNGRGVPDHAERSNHYGLIIMRDRAQSLRGDCQVRRRETGGTEVIVTFIPEKTFSIQ
>CP033756.1|AYY20371.1|592199_592850_+|two-component-system-response-regulator-NarL
MSQQERATILLIDDHPMLRTGVKQLISMAPDIQVIGEASNGAQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRVVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATSDRDISQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
>CP033756.1|AYY20372.1|592846_594229_-|YchO-family-inverse-autotransporter-domain-containing-protein
MAVSFRLLPTLTFLLLLPGVPVWALTASDTTRPAQAQDPLPDMGIAPQVDDDARHFAEVAKKFGEASMSDNGLTAGEQAQLFAISKIGNEVSHQLESWLSPWGNANVDLLVDKEGKFTGSKGSWFVPLQDNDRYLTWNQYSVTRREHDLVGNIGLGQRWRVGGWLLGYNSFYDKVLSESLARGSVGAEAWGEYLRLSANYYHPLGDWQLRDNQTQEQRMAAGYDVTAQARLPFYQHINTSVSVEQYFGDSVDLFHSGTGYHNPVAVSVGLNYTPVPLVTVTAKHKQGENGVSQNNVGLKLNYRFGVPLKQQLAADEVAISNSLRGSRFDSPERDNLPVVEYRQRKNLTVYLATPPWDLQSGETVQLKLQIHSLHGIKALHWQGDTQALSLTPPVDASSPDGWSIIMPVWNSEPGAANRWRLSVVVEDKQGQRVSSNEIALALTEPLVKFTTPGVSWTDSP

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Crispr_ID: CP033756_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033756_3

3345157-3345273

Orphan

Consensus_repeat	Method
CTACGCTTAGCCGGGCTACCGAACGTCGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033756_3

>merge|CP033756|3|3345157-3345273|CRISPRCasFinder
CTACGCTTAGCCGGGCTACCGAACGTCGCGGGTTGTGTAGCCCGGGTAAGGCGCGAATCGCCGCCCCGGGACATACCCCGGCTTGCGCTACGCTTAGCCGGGCTACCGAACATCGCG

>CP033756|3|2|3345157-3345273|CRISPRCasFinder
CTACGCTTAGCCGGGCTACCGAACGTCGCG	GGTTGTGTAGCCCGGGTAAGGCGCGAATCGCCGCCCCGGGACATACCCCGGCTTGCG
CTACGCTTAGCCGGGCTACCGAACATCGCG

Protein	Signature genes	Signature genes Name	Protein_function
CP033756.1\|AYY22849.1\|3344101_3345118_+\|Ldh-family-oxidoreductase	unknown	unknown	gnl\|CDD\|376860
CP033756.1\|AYY22857.1\|3351624_3352488_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
CP033756.1\|AYY22850.1\|3345322_3346543_-\|amino-acid-deaminase	unknown	unknown	gnl\|CDD\|143492
CP033756.1\|AYY22846.1\|3342261_3342894_-\|2-hydroxyhepta-2,4-diene-1,7-dioate-isomerase	unknown	unknown	gnl\|CDD\|185125
CP033756.1\|AYY22843.1\|3339178_3340036_-\|3,4-dihydroxyphenylacetate-2,3-dioxygenase	unknown	unknown	gnl\|CDD\|131351
CP033756.1\|AYY22851.1\|3346586_3346766_-\|hypothetical-protein	unknown	unknown	unknown
CP033756.1\|AYY22852.1\|3346743_3348183_+\|D-aminoacylase	unknown	unknown	gnl\|CDD\|238622
CP033756.1\|AYY22841.1\|3337876_3338680_-\|2-oxo-hepta-3-ene-1,7-dioic-acid-hydratase	unknown	unknown	gnl\|CDD\|131365
CP033756.1\|AYY22859.1\|3353123_3353954_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP033756.1\|AYY22853.1\|3348193_3348586_+\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100004
CP033756.1\|AYY22845.1\|3341500_3342265_-\|2-hydroxyhepta-2,4-diene-1,7-dioate-isomerase	unknown	unknown	gnl\|CDD\|185125
CP033756.1\|AYY22858.1\|3352557_3353091_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP033756.1\|AYY22844.1\|3340037_3341504_-\|5-carboxymethyl-2-hydroxymuconate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143412
CP033756.1\|AYY22840.1\|3337068_3337866_-\|4-hydroxy-2-oxoheptanedioate-aldolase	unknown	unknown	gnl\|CDD\|131364
CP033756.1\|AYY22842.1\|3338788_3339169_-\|5-carboxymethyl-2-hydroxymuconate-Delta-isomerase	unknown	unknown	gnl\|CDD\|184991
CP033756.1\|AYY22855.1\|3350169_3351042_+\|2-dehydro-3-deoxygalactonokinase	unknown	unknown	gnl\|CDD\|377446
CP033756.1\|AYY22847.1\|3343180_3343621_+\|homoprotocatechuate-degradation-operon-regulator-HpaR	unknown	unknown	gnl\|CDD\|188209
CP033756.1\|AYY22854.1\|3348688_3350173_+\|sodium:solute-symporter-family-protein	unknown	unknown	gnl\|CDD\|271357
CP033756.1\|AYY22856.1\|3351028_3351628_+\|2-dehydro-3-deoxy-6-phosphogalactonate-aldolase	unknown	unknown	gnl\|CDD\|181670
CP033756.1\|AYY22848.1\|3343831_3343996_-\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP033756.1\|AYY22849.1\|3344101_3345118_+\|Ldh-family-oxidoreductase	gnl\|CDD\|376860	pfam02615, Ldh_2, Malate/L-lactate dehydrogenase. This family consists of bacterial and archaeal Malate/L-lactate dehydrogenase. L-lactate dehydrogenase, EC:1.1.1.27, catalyzes the reaction (S)-lactate + NAD(+) <=> pyruvate + NADH. Malate dehydrogenase, EC:1.1.1.37 and EC:1.1.1.82, catalyzes the reactions: (S)-malate + NAD(+) <=> oxaloacetate + NADH, and (S)-malate + NADP(+) <=> oxaloacetate + NADPH respectively.	2.70849e-123
CP033756.1\|AYY22857.1\|3351624_3352488_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	7.56206e-75
CP033756.1\|AYY22850.1\|3345322_3346543_-\|amino-acid-deaminase	gnl\|CDD\|143492	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase. This subfamily is composed of Burkholderia cepacia cryptic D-serine dehydratase (cryptic DSD), which is also called D-serine deaminase, and similar bacterial proteins. Members of this subfamily are fold type III PLP-dependent enzymes with similarity to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as dimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on similarity, it is possible cryptic DSDs may also form dimers. Cryptic DSDs are distinct from the ubiquitous bacterial DSDs coded by the dsdA gene, mammalian L-serine dehydratases (LSD) and mammalian serine racemase (SerRac), which are fold type II PLP-dependent enzymes. At present, the enzymatic and biochemical properties of cryptic DSDs are still poorly understood. Typically, DSDs catalyze the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia.	0
CP033756.1\|AYY22846.1\|3342261_3342894_-\|2-hydroxyhepta-2,4-diene-1,7-dioate-isomerase	gnl\|CDD\|185125	PRK15203, PRK15203, 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional.	8.3687e-131
CP033756.1\|AYY22843.1\|3339178_3340036_-\|3,4-dihydroxyphenylacetate-2,3-dioxygenase	gnl\|CDD\|131351	TIGR02298, putative_34-dihydroxyphenylacetate_23-dioxygenase, 3,4-dihydroxyphenylacetate 2,3-dioxygenase. This enzyme catalyzes the ring-opening step in the degradation of 4-hydroxyphenylacetate.	0
CP033756.1\|AYY22852.1\|3346743_3348183_+\|D-aminoacylase	gnl\|CDD\|238622	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics.	3.00951e-159
CP033756.1\|AYY22841.1\|3337876_3338680_-\|2-oxo-hepta-3-ene-1,7-dioic-acid-hydratase	gnl\|CDD\|131365	TIGR02312, 2-keto-4-pentenoate_hydratase, 2-oxo-hepta-3-ene-1,7-dioic acid hydratase. This model represents the enzyme which hydrates the double bond of 2-oxo-hepta-3-ene-1,7-dioic acid to form 4-hydroxy-2-oxo-heptane-1,7-dioic acid in the catabolism of 4-hydroxyphenylacetic acid. The gene for this enzyme is generally found adjacent to other genes of this pathway in an apparent operon.	2.25294e-174
CP033756.1\|AYY22859.1\|3353123_3353954_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.44259e-15
CP033756.1\|AYY22853.1\|3348193_3348586_+\|RidA-family-protein	gnl\|CDD\|100004	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	6.24608e-31
CP033756.1\|AYY22845.1\|3341500_3342265_-\|2-hydroxyhepta-2,4-diene-1,7-dioate-isomerase	gnl\|CDD\|185125	PRK15203, PRK15203, 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional.	1.28668e-143
CP033756.1\|AYY22858.1\|3352557_3353091_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.7483e-14
CP033756.1\|AYY22844.1\|3340037_3341504_-\|5-carboxymethyl-2-hydroxymuconate-semialdehyde-dehydrogenase	gnl\|CDD\|143412	cd07093, ALDH_F8_HMSADH, Human aldehyde dehydrogenase family 8 member A1-like. In humans, the aldehyde dehydrogenase family 8 member A1 (ALDH8A1) protein functions to convert 9-cis-retinal to 9-cis-retinoic acid and has a preference for NAD+. Also included in this CD is the 2-hydroxymuconic semialdehyde dehydrogenase (HMSADH) which catalyzes the conversion of 2-hydroxymuconic semialdehyde to 4-oxalocrotonate, a step in the meta cleavage pathway of aromatic hydrocarbons in bacteria. Such HMSADHs seen here are: XylG of the TOL plasmid pWW0 of Pseudomonas putida, TomC of Burkholderia cepacia G4, and AphC of Comamonas testosterone.	0
CP033756.1\|AYY22840.1\|3337068_3337866_-\|4-hydroxy-2-oxoheptanedioate-aldolase	gnl\|CDD\|131364	TIGR02311, 24-dihydroxyhept-2-ene-17-dioic_acid_aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase. This model represents the aldolase which performs the final step unique to the 4-hydroxyphenylacetic acid catabolism pathway in which 2,4-dihydroxyhept-2-ene-1,7-dioic acid is split into pyruvate and succinate-semialdehyde. The gene for enzyme is generally found adjacent to other genes for this pathway organized into an operon.	3.58131e-152
CP033756.1\|AYY22842.1\|3338788_3339169_-\|5-carboxymethyl-2-hydroxymuconate-Delta-isomerase	gnl\|CDD\|184991	PRK15031, PRK15031, 5-carboxymethyl-2-hydroxymuconate Delta-isomerase.	5.28758e-95
CP033756.1\|AYY22855.1\|3350169_3351042_+\|2-dehydro-3-deoxygalactonokinase	gnl\|CDD\|377446	pfam05035, DGOK, 2-keto-3-deoxy-galactonokinase. 2-keto-3-deoxy-galactonokinase EC:2.7.1.58 catalyzes the second step in D-galactonate degradation.	7.79723e-113
CP033756.1\|AYY22847.1\|3343180_3343621_+\|homoprotocatechuate-degradation-operon-regulator-HpaR	gnl\|CDD\|188209	TIGR02337, Homoprotocatechuate_degradative_operon_repressor., homoprotocatechuate degradation operon regulator, HpaR. This Helix-Turn-Helix transcriptional regulator is a member of the MarR family (pfam01047) and is found in association with operons for the degradation of 4-hydroxyphenylacetic acid via homoprotocatechuate.	4.17885e-59
CP033756.1\|AYY22854.1\|3348688_3350173_+\|sodium:solute-symporter-family-protein	gnl\|CDD\|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	1.5877e-87
CP033756.1\|AYY22856.1\|3351028_3351628_+\|2-dehydro-3-deoxy-6-phosphogalactonate-aldolase	gnl\|CDD\|181670	PRK09140, PRK09140, 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed.	2.15312e-108

>CP033756.1|AYY22849.1|3344101_3345118_+|Ldh-family-oxidoreductase
MESVTLSLPEAYDLALEVLSANGFSADHAAAIARNVTAGERDGCASHGLWRMLGIVDTLRKGKVSPDAEPQIHDQAPGIARADAGGAFSLLAYERALPLLLEKARHNGIAALAINRCVHFSALFADIEPLTEAGLVGLACTPSHAWVAPAGGTRPLFGTNPIAFGWPRQDKPPFIVDMATSAAARGEIQLHQRAGKALPEGWGIDSQGQPTTDAAEVLNGAMLTFGGHKGSALAAMVELLAGPLIGDMTSAESLAWDNGAGGLPYGGELILALDPQRFLGAQAPEQLERAETLFNAMQDQGARLPGERRFACRQQSERQGVIISRSLHDEICALRQGG
>CP033756.1|AYY22848.1|3343831_3343996_-|pyridine-nucleotide-disulfide-oxidoreductase
MKGARLIARPSVHNALFETADGGGVVYWQKLILCCSAGSASPRPSTAPSGWRSR
>CP033756.1|AYY22847.1|3343180_3343621_+|homoprotocatechuate-degradation-operon-regulator-HpaR
MHDSLTIALLQAREAAMAYFRPIVKRHNLTEQQWRIVRILAERPSMDFHDLAFRACILRPSLTGILTRMERDGLVLRLKPVNDQRKLYVSLTPAGTALYESAQAEVEETYRLLEAQFTTEKLQQLTSLLEEFIALGVPAGRGDEEE
>CP033756.1|AYY22846.1|3342261_3342894_-|2-hydroxyhepta-2,4-diene-1,7-dioate-isomerase
MKGTIFAVALNHRSQLDAWREAFQQAPYKTPPKTAVWFIKPRNTVIGDGEAIPYPQGETVQSGATVALIVGKTARKVAAEEAANYIAGYALANDVSLPEESFYRPAIKAKCRDGFCPIGTLSAVRNVDDLTIITEINGREADSWHTGDLQRNAAQLLSALSEFATLNPGDAILIGTPHSRVTLRPGDRVRILADGFPALENPVVAEGELA
>CP033756.1|AYY22845.1|3341500_3342265_-|2-hydroxyhepta-2,4-diene-1,7-dioate-isomerase
MKQARIEWQGQVRDVLVNERDQVRLDDGTVLKEGEFRWLPPADGTLFALGLNYADHASELEFKPPTEPLVFIKAPNTFIGHQQQSVRPDNVEYMHYEAELVVVIGKTARRVSEAEAMDYVAGYTVCNDYAIRDYLENYYRPNLRVKSRDTLTPIGPWIVSKEAIPDPHNLALRTWVNGELRQQGTTADLIFSIPFLIAYLSEFMTLQPGDMIATGTPKGLSDVVPGDEVIVEVEGVGRLVNHIISQQAYEETLS
>CP033756.1|AYY22844.1|3340037_3341504_-|5-carboxymethyl-2-hydroxymuconate-semialdehyde-dehydrogenase
MKKINHWINGKNVAGADYFHTTNPATGEVLAEVASGGEAEINQAVAAAKEAFPKWANLPMKERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAPCLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKKYSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPTDPNTQVGALISQQHWEKVSGYIRLGIEEGATLLAGGADKPSDLPAHLKTGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGDHPIPKWGV
>CP033756.1|AYY22843.1|3339178_3340036_-|3,4-dihydroxyphenylacetate-2,3-dioxygenase
MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEIGKRCREMGVDTIIVFDTHWLVNSAYHINCADHFQGVYTSNELPHFIRDMTYDYDGNPELGQLIADEAVKLGVRAKAHNIPSLKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRRLGEAILKAIEKYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWREGKFKEFCTMLPEYADYCYGEGNMHDTVMLLGLLGWDKYDGKVEFITELFASSGTGQVNAVFPLPAQA
>CP033756.1|AYY22842.1|3338788_3339169_-|5-carboxymethyl-2-hydroxymuconate-Delta-isomerase
MPHFIAECTDNIREQADLPGLFAKVNEALAATGIFPIGGIRSRAHWLDTWQMADGRQDYAFVHITLKIGAGRSLESRQDVGDMLFALIKSHFATLMESRYLALSFAMEELDPTLNYKQNNVHALFK
>CP033756.1|AYY22841.1|3337876_3338680_-|2-oxo-hepta-3-ene-1,7-dioic-acid-hydratase
MLDKQTRTLIAQRLNQAEKQREQIRAISLDYPSITIEDAYAVQREWVEMKIAEGRVLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIDPETQRPRKVFDTISDNAANAGVILGGRPIKPDELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGAISCRFV
>CP033756.1|AYY22840.1|3337068_3337866_-|4-hydroxy-2-oxoheptanedioate-aldolase
MNNAFKDALKAGRPQIGLWLGLCSSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLVPMVQNAEEARLAVRATRYPPAGIRGVGSALARASRWNRVPDYIHQANDAMCVLVQIETREALKNLPQILDVDGVDGVFIGPADLSADMGHGGNPQHPEVQAAIEDAIQQIRQAGKAPGILMANEQLAKRYLELGALFVAVGVDTTLLARGAEALAARFTHNATTTTDNNKSVY
>CP033756.1|AYY22850.1|3345322_3346543_-|amino-acid-deaminase
MKYHSAPLIPHKSALMSAPANLLAEEVCLPAALLKKSALENNISWMQRYADARGVSLAPHGKTTMTPWIFQAQQRAGAWGIGVGSAWQASAAMASGIQRVLMVNQLVGKANMQVVAQLKAHYRAVDFICCVDSEANVRTLSAFFAAQGQTLDVLIELGVPGGRCGCRSVDDALALAQRVSDLPGLRLRGLELYEGVLHGDDPQPQVEALLQQAAALACRMEPLVDGEFILTGAGTVWYDVVCNIWLAAAKPRRCRIVIRPGCYITHDRGIYDLAQQALIARDPIACDLAGDLTSALELMAMVQSVPEADRAVVNFGKRDCAFDAGLPQPIAHYRNGQQLALRAESIVSTGIMDQHCMLRLAPGSDVQVGDILLFGTSHPCLTFDKWKTLLLVDDDYNVLDELDTLF
>CP033756.1|AYY22851.1|3346586_3346766_-|hypothetical-protein
MKSQSTFIAITPFRHADKLTIYKRKKQWKTTQNSDRFVILLFKTNNIFILKIYLSNSYK
>CP033756.1|AYY22852.1|3346743_3348183_+|D-aminoacylase
MKVDWLFKNVTVIDGSGGPQYRADVAVKGDRIMAIAPALDVAAEQVIDGQGRVLAPGFIDVHTHDDINVIRMPEYLPKLSQGVTTVIVGNCGISAATATMRGEVPDPMNLLGEQQHFIYPTVEAYAHAVEAARPSLNVGTLIGHTALRNNHMDDLFRPANETEIAGMRVQLRDALRQGALGLSTGLAYASAFQSTTEEVMALAEELAAGKGVYTTHLRSEFEPILEALDEAFRIGRHGNVPVVVSHHKCAGAKNWGRTKETLAFFDEMRQQQDIACDCYPYSASSSTLDMKQVTDEFDIVITWSEAQPEQAGKTLQQIADEWQVSLHDAAARLMPAGAIYHNMDEQDVRRVMRYPVTMIGSDGLPNDPMPHPRLWGAFPRVLGHYSRDEQLFPLTTAVHKMTGLSAARFQLADRGLVKIGYFADLVLFDPQTVRDVASFSDPKRPADGIEAVMVNGVMSYGSDKKITGRAGRFLRRRMD
>CP033756.1|AYY22853.1|3348193_3348586_+|RidA-family-protein
MSIKRYGVEGGTGTGGQHLPFARAVEAGGWLYVSGQTPMKNGEVVEGGIVDQSRLAIQNCVDIMTEAGYTLADVVHVKVILTDARYFQSFNKVFREFFGDNPPARICCVADLVADCKVEVDVTCFNASRA
>CP033756.1|AYY22854.1|3348688_3350173_+|sodium:solute-symporter-family-protein
MNSHVFLVGFIIYALAMIWLGWYVSRHQKSGEDFLLGGRSLPLFLTLGSTVATMVGTGSSMGAVGFGYSNGWAGMLYGVGGAIGILLVAWLFAPVRKLRFMTMSEELSYYTGGSHLIKNLVGIMIFIASIGWLGAHILGGSMYLAWATGINLTVAKIIIAMAFAIYVIIGGYSAVVWTDTIQALILFFGFILMAILAVVHVGGWDAIVQAMDPKAMSLFAVDKLGTIPALSLAMVIGVGVLATPSYRQRIYSGKDVSSVRRSFVYTGVLYLFFSVLPAVIGMAAWTMNPNLENSNYAFLFATSFLPAILGLVVLIAGLSATMSSASSDAIAAVAIMMRDVYTLVTGKMPPAHKAITLSRWMLAFVIGLAMIFALTSNDIISYITKMISMLMSGLFVCSILGRFWLRFNWQGALTALLSGMLVSIVVLVKADWLAYWGNPCIPSVVGSFVSAIFVTVMTPASKISRQQALEMITQEREGEAIPAKTVVQVSGETQ
>CP033756.1|AYY22855.1|3350169_3351042_+|2-dehydro-3-deoxygalactonokinase
MKDYIAVDWGSTQLRGWLIRNGQCVETKQLPMGITRLNGRSPADVFAEHLAPWRGAQALPVLMAGMIGSDAGWQAVPYLDCPTAIDAPGRQLCAVAEGVWIIPGLKIEQDGDFNVMRGEETQLLGACQLAPAECYVLPGTHCKWVQVVGGGVRHFATAMTGELHHLLMTQSLIGKGLPAQQPDDAAFERGLEKGLAQPSLISELFVARAARVLGGLAASSVSDYLSGLLIGAEVATLGQRFRTSAVTLVGEPALNARYGRAMKARGMMVNSCSGDEALLAGMARIMHEQD
>CP033756.1|AYY22856.1|3351028_3351628_+|2-dehydro-3-deoxy-6-phosphogalactonate-aldolase
MNKIKLVAILRGIQPGEAAEHIAALIEAGFRYIEIPLNSPDWQQSIPAMVRQFGERAMIGAGTVLKVEQVDFLAEAGAKLIVTPNTAPAVIRRAVDKGMLVCAGCATASEAFSALDAGAQWLKIFPSSAFGADYIRALKAVLPPEVPVLAVGGVTPESLATWIQAGCAGAGLGSDLYRAGQAVERTREQAERFISASKS
>CP033756.1|AYY22857.1|3351624_3352488_-|MurR/RpiR-family-transcriptional-regulator
MSWSIDIISCITDRFVELTATEKRIAQFILDDVAAAAELPIAEIARLTQTSQASVTRFARALGCKDVRELKMKLAQSLAVGQRFILDVPDLEGVQGIYESIISVLETNRRALDIEALKRAVSWLSDARQILALGMGGGSTICAQEIQYRLFRLGLPVVSQSDGLLVRMMSSAVTPQDVVIVLSLGGYTREIIESAAIASQYGAKVIAITPAGTPLAEQADLVLPLLVRENDYIFKPSTSRYAMLAMVDVLATELAMANKPQAKGKLRRIKLALDSHRGGVDRQPLGD
>CP033756.1|AYY22858.1|3352557_3353091_-|GNAT-family-N-acetyltransferase
MKTNTITAGAVLRLTQESDIALLPAIERSAAQAFRQIPSLAWLADSEVISVARHHDYLETEHSLLAVAAGQPVGFILTEPLDDALFIVEVAVHQAWQQQGIGWMLLERVIESARQMGYPAVTLTTFREVPWNAPFYTRLGFAMLDELTLPAGLAAKREQETRHGLPPESRCAMRLAL
>CP033756.1|AYY22859.1|3353123_3353954_+|GNAT-family-N-acetyltransferase
MELTAVPATQFSSVQLTDILNACFEAYLVPVTQSVEGFVQRFSAEGMSLVDSRVWLAGDEPAAIAIVARRGSAARLAAFALRPAWRGKGLGRKLMQELLMLLQQQGIETVFLEVIRDNHAAVALYQSLGFTRRYGLCGYLSTELLAPVPGILQLYPTLSLLRRAIEESNSQLPWLLDPLTFATLPCQVVTLEQRAFAVLTTAGSRPVLSFLWVEPAARRQGLARELLMALAQQFPGIGTSVTVPETFTPLFAAAGYTPLSLQQYEMTMDLADAKSA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP033756_1	1.1\|470155\|57\|CP033756\|PILER-CR	470155-470211	57	CP033756.1	470630-470686	0	1.0
CP033756_1	1.2\|470274\|57\|CP033756\|PILER-CR	470274-470330	57	CP033756.1	470630-470686	0	1.0
CP033756_1	1.3\|470393\|57\|CP033756\|PILER-CR	470393-470449	57	CP033756.1	470630-470686	0	1.0
CP033756_1	1.1\|470155\|57\|CP033756\|PILER-CR	470155-470211	57	CP033756.1	470512-470568	1	0.982
CP033756_1	1.1\|470155\|57\|CP033756\|PILER-CR	470155-470211	57	CP033756.1	470749-470805	1	0.982
CP033756_1	1.1\|470155\|57\|CP033756\|PILER-CR	470155-470211	57	CP033756.1	470867-470923	1	0.982
CP033756_1	1.2\|470274\|57\|CP033756\|PILER-CR	470274-470330	57	CP033756.1	470512-470568	1	0.982
CP033756_1	1.2\|470274\|57\|CP033756\|PILER-CR	470274-470330	57	CP033756.1	470749-470805	1	0.982
CP033756_1	1.2\|470274\|57\|CP033756\|PILER-CR	470274-470330	57	CP033756.1	470867-470923	1	0.982
CP033756_1	1.3\|470393\|57\|CP033756\|PILER-CR	470393-470449	57	CP033756.1	470512-470568	1	0.982
CP033756_1	1.3\|470393\|57\|CP033756\|PILER-CR	470393-470449	57	CP033756.1	470749-470805	1	0.982
CP033756_1	1.3\|470393\|57\|CP033756\|PILER-CR	470393-470449	57	CP033756.1	470867-470923	1	0.982

1. spacer 1.1|470155|57|CP033756|PILER-CR matches to position: 470630-470686, mismatch: 0, identity: 1.0

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************************************************

2. spacer 1.2|470274|57|CP033756|PILER-CR matches to position: 470630-470686, mismatch: 0, identity: 1.0

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************************************************

3. spacer 1.3|470393|57|CP033756|PILER-CR matches to position: 470630-470686, mismatch: 0, identity: 1.0

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************************************************

4. spacer 1.1|470155|57|CP033756|PILER-CR matches to position: 470512-470568, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagctcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************.***********************************

5. spacer 1.1|470155|57|CP033756|PILER-CR matches to position: 470749-470805, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagctcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************.***********************************

6. spacer 1.1|470155|57|CP033756|PILER-CR matches to position: 470867-470923, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagttcgtaggcccggcaaggcgcagccgccaccgggca	Protospacer
**********************************.**********************

7. spacer 1.2|470274|57|CP033756|PILER-CR matches to position: 470512-470568, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagctcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************.***********************************

8. spacer 1.2|470274|57|CP033756|PILER-CR matches to position: 470749-470805, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagctcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************.***********************************

9. spacer 1.2|470274|57|CP033756|PILER-CR matches to position: 470867-470923, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagttcgtaggcccggcaaggcgcagccgccaccgggca	Protospacer
**********************************.**********************

10. spacer 1.3|470393|57|CP033756|PILER-CR matches to position: 470512-470568, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagctcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************.***********************************

11. spacer 1.3|470393|57|CP033756|PILER-CR matches to position: 470749-470805, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagctcgtaggcccggtaaggcgcagccgccaccgggca	Protospacer
*********************.***********************************

12. spacer 1.3|470393|57|CP033756|PILER-CR matches to position: 470867-470923, mismatch: 1, identity: 0.982

tttccgtgacatttgtcgcagttcgtaggcccggtaaggcgcagccgccaccgggca	CRISPR spacer
tttccgtgacatttgtcgcagttcgtaggcccggcaaggcgcagccgccaccgggca	Protospacer
**********************************.**********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

933620 : 940525

Bacillus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYY20672.1\|933620_935099_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	8.5e-30	28.3
AYY20673.1\|935095_935818_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
AYY20674.1\|936136_937498_+	U32 family peptidase	Q6DW11	Phage_TP	1.8e-207	94.8
AYY24627.1\|937743_938637_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	3.6e-15	29.8
AYY20675.1\|938877_939651_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	36.7
AYY24628.1\|939661_940525_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5

DBSCAN-SWA_2

3949410 : 3998283

Cronobacter_phage(25.49%)

integrase,head,coat,tRNA

attL 3952293:3952339|attR 3998895:3998941

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYY23378.1\|3949410_3950796_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.5e-46	35.4
AYY23379.1\|3950841_3951054_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
AYY23380.1\|3951055_3951922_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8
3952293:3952339	attL	NA	NA	NA	NA
AYY24742.1\|3952352_3953396_-\|integrase	site-specific integrase	G8C7S0	Escherichia_phage	8.5e-178	85.6
AYY23381.1\|3953392_3953728_-	DNA-binding protein	NA	NA	NA	NA
AYY23382.1\|3953729_3953948_-	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	3.4e-12	52.2
AYY23383.1\|3953944_3954136_-	DUF1382 family protein	A0A0P0ZC60	Stx2-converting_phage	6.0e-13	62.7
AYY23384.1\|3954132_3954618_-	hypothetical protein	A0A076G835	Escherichia_phage	2.5e-31	62.9
AYY23385.1\|3954614_3954839_-	hypothetical protein	G8C7U9	Escherichia_phage	7.0e-21	73.2
AYY24743.1\|3955054_3955582_-	phage N-6-adenine-methyltransferase	G8EYI1	Enterobacteria_phage	1.3e-57	62.8
AYY23386.1\|3955610_3956234_-	exonuclease	A0A0S2SY31	Pseudomonas_phage	5.3e-58	60.2
AYY23387.1\|3956230_3956977_-	phage recombination protein Bet	A0A0M4RD39	Salmonella_phage	3.1e-65	67.7
AYY23388.1\|3956993_3957278_-	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	4.3e-39	79.8
AYY23389.1\|3957366_3957561_-	hypothetical protein	NA	NA	NA	NA
AYY23390.1\|3957988_3958192_+	hypothetical protein	A0A192Y6Q5	Salmonella_phage	2.3e-18	70.1
AYY23391.1\|3958228_3959110_-	hypothetical protein	NA	NA	NA	NA
AYY23392.1\|3959096_3959861_-	hypothetical protein	NA	NA	NA	NA
AYY24744.1\|3959985_3960105_-	hypothetical protein	NA	NA	NA	NA
AYY23393.1\|3960127_3960817_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.0e-86	70.6
AYY23394.1\|3960921_3961155_+	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	3.0e-22	70.4
AYY23395.1\|3961194_3961416_+	transcriptional regulator	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
AYY24745.1\|3961549_3962278_+	helix-turn-helix domain-containing protein	H9C164	Pectobacterium_phage	7.8e-37	73.0
AYY23396.1\|3962274_3963051_+	replication protein	A0A193GYX1	Enterobacter_phage	1.1e-94	65.0
AYY23397.1\|3963050_3963353_+	MarR family transcriptional regulator	NA	NA	NA	NA
AYY23398.1\|3963349_3963757_+	hypothetical protein	NA	NA	NA	NA
AYY23399.1\|3963753_3964014_+	DUF4752 family protein	T1S9K2	Salmonella_phage	2.8e-29	75.6
AYY23400.1\|3964120_3964804_+	ead/Ea22-like family protein	A0A075B8K3	Enterobacteria_phage	2.1e-31	45.6
AYY24746.1\|3965372_3966098_+	DUF551 domain-containing protein	K7PH64	Enterobacterial_phage	9.9e-16	47.0
AYY23401.1\|3966097_3966286_+	hypothetical protein	R9TNE4	Aeromonas_phage	5.5e-19	75.0
AYY23402.1\|3966451_3966772_+	hypothetical protein	NA	NA	NA	NA
AYY23403.1\|3967032_3967629_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.4e-55	53.8
AYY24747.1\|3967634_3967805_+	NinE family protein	G8C7V4	Escherichia_phage	2.8e-14	71.4
AYY23404.1\|3967797_3968433_+	NinG family protein	M9NYX8	Enterobacteria_phage	2.0e-81	78.4
AYY23405.1\|3968429_3968570_+	YlcG family protein	NA	NA	NA	NA
AYY23406.1\|3968566_3969376_+	antitermination protein	M9NZB0	Enterobacteria_phage	3.8e-117	75.5
AYY23407.1\|3969693_3969888_-	hypothetical protein	NA	NA	NA	NA
AYY23408.1\|3969882_3970197_+	hypothetical protein	H6WRZ3	Salmonella_phage	6.3e-44	86.1
AYY23409.1\|3970199_3970694_+	lysozyme	M9P0E5	Enterobacteria_phage	2.1e-86	92.1
AYY23410.1\|3970690_3971041_+	hypothetical protein	H2EQH5	Salmonella_phage	4.6e-11	38.9
AYY23411.1\|3971787_3972423_+	hypothetical protein	I6S676	Salmonella_phage	2.3e-101	81.1
AYY23412.1\|3972453_3972933_+	DUF2280 domain-containing protein	F1C5D6	Cronobacter_phage	2.5e-63	74.8
AYY23413.1\|3972919_3974392_+	DNA-packaging protein	G0ZND4	Cronobacter_phage	7.9e-254	86.1
AYY23414.1\|3974403_3975852_+	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	1.5e-119	51.5
AYY23415.1\|3975769_3976774_+\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	2.9e-114	68.7
AYY23416.1\|3977186_3978572_+	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	5.8e-166	64.0
AYY23417.1\|3978575_3979007_+	hypothetical protein	F1C5E0	Cronobacter_phage	6.2e-42	60.8
AYY23418.1\|3979018_3980116_+\|coat	phage coat protein	F1C5E1	Cronobacter_phage	3.2e-151	73.6
AYY23419.1\|3980125_3980446_+	hypothetical protein	NA	NA	NA	NA
AYY23420.1\|3980448_3980829_+	hypothetical protein	F1C5E2	Cronobacter_phage	1.4e-29	56.1
AYY23421.1\|3980828_3981002_+	50S ribosomal protein L13	I6R0P9	Salmonella_phage	1.9e-13	56.1
AYY23422.1\|3981001_3981364_+	hypothetical protein	A0A0M3LSC9	Mannheimia_phage	5.6e-20	48.3
AYY23423.1\|3981366_3981792_+	HK97 gp10 family phage protein	R9TPP7	Aeromonas_phage	1.3e-28	48.6
AYY23424.1\|3981788_3982181_+	hypothetical protein	G0ZNE4	Cronobacter_phage	9.7e-34	51.2
AYY23425.1\|3982249_3983002_+	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	5.8e-43	42.1
AYY23426.1\|3983054_3983732_+	hypothetical protein	F1C5E8	Cronobacter_phage	1.8e-72	57.5
AYY23427.1\|3983907_3984663_+	DNA-binding protein	K7PGT4	Enterobacteria_phage	1.8e-60	51.0
AYY23428.1\|3984665_3984920_+	hypothetical protein	K7PM89	Enterobacteria_phage	6.7e-20	73.0
AYY24748.1\|3984994_3985333_+	hypothetical protein	NA	NA	NA	NA
AYY24749.1\|3985340_3985661_+	hypothetical protein	NA	NA	NA	NA
AYY23429.1\|3985712_3985901_-	hypothetical protein	NA	NA	NA	NA
AYY24750.1\|3986124_3986352_+	hypothetical protein	NA	NA	NA	NA
AYY23430.1\|3986454_3986958_+	hypothetical protein	NA	NA	NA	NA
AYY23431.1\|3987052_3990493_+	hypothetical protein	Q5G8W8	Enterobacteria_phage	7.5e-154	46.2
AYY23432.1\|3990492_3991026_+	hypothetical protein	NA	NA	NA	NA
AYY24751.1\|3991125_3991545_+	hypothetical protein	A0A2P1MXB5	Escherichia_phage	4.1e-30	47.1
AYY23433.1\|3991544_3992015_+	hypothetical protein	R9TPR6	Aeromonas_phage	9.6e-28	40.4
AYY23434.1\|3992011_3992407_+	hypothetical protein	F1C5F2	Cronobacter_phage	1.2e-36	55.6
AYY23435.1\|3992393_3994871_+	MoaD/ThiS family protein	F1C5A7	Cronobacter_phage	3.9e-197	45.6
AYY23436.1\|3996754_3997372_+	hypothetical protein	NA	NA	NA	NA
AYY23437.1\|3997380_3998283_+	hypothetical protein	D4P7M2	Rhodococcus_phage	5.3e-35	36.6
3998895:3998941	attR	NA	NA	NA	NA

DBSCAN-SWA_3

5175621 : 5228206

Salmonella_phage(20.45%)

integrase,lysis,coat,tail,terminase

attL 5178661:5178676|attR 5224769:5224784

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYY24452.1\|5175621_5177085_+	fructuronate reductase	H8ZJP8	Ostreococcus_tauri_virus	7.8e-44	30.3
AYY24453.1\|5177350_5177782_+	universal stress protein UspG	A0A1W6JNV4	Morganella_phage	2.7e-21	40.7
AYY24454.1\|5177832_5178519_-	GntR family transcriptional regulator	NA	NA	NA	NA
AYY24455.1\|5178610_5179360_-	bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG	NA	NA	NA	NA
5178661:5178676	attL	NA	NA	NA	NA
AYY24456.1\|5179490_5181533_+	peptidyl-dipeptidase Dcp	A0A1V0SIU1	Klosneuvirus	1.1e-16	20.5
AYY24457.1\|5181686_5182826_-\|integrase	integrase	Q77Z04	Phage_21	3.5e-92	48.2
AYY24458.1\|5182806_5183064_-	hypothetical protein	NA	NA	NA	NA
AYY24459.1\|5183123_5183363_-	DUF4060 family protein	M9P0E0	Enterobacteria_phage	2.5e-24	70.5
AYY24809.1\|5183403_5184513_-	enterohemolysin	H6WRX0	Salmonella_phage	1.7e-184	86.4
AYY24460.1\|5184525_5187636_-	exodeoxyribonuclease	H6WRX1	Salmonella_phage	3.6e-296	57.8
AYY24461.1\|5187773_5187929_-	hypothetical protein	K7PGY4	Enterobacteria_phage	2.0e-14	71.2
AYY24462.1\|5187937_5188129_-	DUF1482 family protein	NA	NA	NA	NA
AYY24810.1\|5188235_5188334_-	hypothetical protein	NA	NA	NA	NA
AYY24463.1\|5188703_5189276_-	hypothetical protein	NA	NA	NA	NA
AYY24464.1\|5189499_5189679_-	hypothetical protein	NA	NA	NA	NA
AYY24465.1\|5189872_5190286_-	helix-turn-helix domain-containing protein	A0A0M4R5D1	Salmonella_phage	2.1e-47	79.0
AYY24466.1\|5190358_5190586_+	Rha family transcriptional regulator	A0A0M4QX15	Salmonella_phage	1.9e-21	63.5
AYY24467.1\|5190588_5191125_+	hypothetical protein	K7PJT7	Enterobacteria_phage	4.0e-62	68.9
AYY24468.1\|5191253_5192048_+	ParB/RepB/Spo0J family partition protein	C7BGF1	Burkholderia_phage	2.8e-64	51.3
AYY24811.1\|5192113_5192953_+	hypothetical protein	Q8HA96	Salmonella_phage	5.1e-24	52.2
AYY24469.1\|5193712_5194081_+	DUF977 family protein	H6WRX9	Salmonella_phage	8.3e-11	43.0
AYY24470.1\|5194840_5196208_+	hypothetical protein	Q2P9X8	Enterobacteria_phage	1.9e-20	26.9
AYY24471.1\|5196209_5196938_+	hypothetical protein	NA	NA	NA	NA
AYY24472.1\|5197713_5198049_+	hypothetical protein	NA	NA	NA	NA
AYY24473.1\|5198680_5198953_+	colicin immunity protein	NA	NA	NA	NA
AYY24474.1\|5199645_5199879_+	hypothetical protein	A0A0M4R5D9	Salmonella_phage	9.9e-18	57.1
AYY24475.1\|5199914_5200511_+	DUF1367 family protein	K7PKS6	Enterobacteria_phage	1.2e-88	78.6
AYY24476.1\|5200510_5200717_+	hypothetical protein	H6WRY8	Salmonella_phage	1.6e-24	74.2
AYY24477.1\|5200719_5201016_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	1.2e-36	74.0
AYY24478.1\|5201012_5201828_+	antitermination protein	A0A1B5FPA5	Escherichia_phage	5.2e-106	69.6
AYY24479.1\|5202080_5202707_+	DUF1440 domain-containing protein	NA	NA	NA	NA
AYY24480.1\|5203339_5203564_+\|lysis	lysis protein	M9NZI9	Enterobacteria_phage	4.0e-32	91.9
AYY24481.1\|5203541_5204036_+	lysozyme	M9P0E5	Enterobacteria_phage	6.2e-86	92.1
AYY24482.1\|5204032_5204383_+	hypothetical protein	H2EQH5	Salmonella_phage	7.9e-11	38.9
AYY24483.1\|5204583_5204823_-	hypothetical protein	NA	NA	NA	NA
AYY24484.1\|5205962_5206145_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	4.1e-19	75.0
AYY24485.1\|5206403_5206976_+	hypothetical protein	A0A0U2RXY7	Escherichia_phage	3.8e-55	54.3
AYY24486.1\|5206965_5208033_-	hypothetical protein	NA	NA	NA	NA
AYY24487.1\|5208947_5209193_+	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	8.4e-36	100.0
AYY24488.1\|5209542_5210547_+\|terminase	terminase small subunit	Q5QF76	Pseudomonas_virus	3.5e-35	43.8
AYY24489.1\|5210524_5211829_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	2.8e-146	60.3
AYY24490.1\|5211833_5213258_+	DUF4055 domain-containing protein	G8C7P4	Escherichia_phage	3.4e-193	71.7
AYY24491.1\|5213241_5214354_+	hypothetical protein	I6PD76	Cronobacter_phage	4.5e-108	53.6
AYY24492.1\|5214460_5215225_+	hypothetical protein	G8C7P6	Escherichia_phage	2.4e-76	59.1
AYY24493.1\|5215312_5216449_+\|coat	P22 coat - protein 5 family protein	G8C7P7	Escherichia_phage	2.0e-156	75.7
AYY24494.1\|5216488_5216701_+	hypothetical protein	G8C7P8	Escherichia_phage	1.2e-09	53.7
AYY24495.1\|5216704_5217115_+	protein singed	A0A0H5AUF0	Pseudomonas_phage	1.1e-08	38.2
AYY24496.1\|5217116_5217413_+	hypothetical protein	A0A1V0E8A3	Vibrio_phage	5.6e-10	50.0
AYY24497.1\|5217384_5217768_+	glutamate 5-kinase	A0A0S2SYG4	Pseudomonas_phage	3.5e-20	44.4
AYY24498.1\|5217769_5218321_+	hypothetical protein	G8C7Q1	Escherichia_phage	1.7e-28	39.3
AYY24499.1\|5218317_5218710_+	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
AYY24500.1\|5218733_5219666_+	hypothetical protein	A0A0D4DBN5	Acinetobacter_phage	1.7e-23	27.0
AYY24501.1\|5219703_5220186_+	hypothetical protein	NA	NA	NA	NA
AYY24502.1\|5220323_5220521_+	hypothetical protein	NA	NA	NA	NA
AYY24503.1\|5220587_5221271_+	hypothetical protein	A0A0R6PJY5	Moraxella_phage	4.9e-41	42.4
AYY24812.1\|5221379_5221748_+	zinc ribbon domain-containing protein	I6PDJ9	Cronobacter_phage	3.4e-12	40.2
AYY24504.1\|5221820_5224934_+\|tail	phage tail protein	A0A2D1GPC9	Escherichia_phage	3.1e-90	31.9
5224769:5224784	attR	NA	NA	NA	NA
AYY24505.1\|5225017_5225353_+	hypothetical protein	NA	NA	NA	NA
AYY24506.1\|5225666_5226140_+	hypothetical protein	A0A286S298	Klebsiella_phage	2.5e-60	67.9
AYY24507.1\|5226126_5226603_+	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	3.2e-79	93.0
AYY24508.1\|5227825_5228206_+	nitrite transporter	A0A286S2A6	Klebsiella_phage	3.0e-64	88.9

DBSCAN-SWA_4

5256569 : 5267456

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYY24534.1\|5256569_5257190_-	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0
AYY24535.1\|5257182_5258448_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	2.7e-234	100.0
AYY24536.1\|5258459_5259362_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
AYY24537.1\|5259622_5260384_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
AYY24538.1\|5260404_5261265_-	class A broad-spectrum beta-lactamase SHV-1	A0A077SL40	Escherichia_phage	4.4e-156	99.7
AYY24539.1\|5261562_5261823_+	hypothetical protein	A0A077SK33	Escherichia_phage	1.9e-41	100.0
AYY24540.1\|5261909_5262998_+	chromosome segregation protein SMC	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
AYY24541.1\|5263028_5264294_-	MFS transporter	NA	NA	NA	NA
AYY24542.1\|5264348_5267456_-	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP033758

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

20652 : 142484

106

Caulobacter_phage(11.54%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYY24843.1\|20652_21657_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AYY24844.1\|22003_22282_-	DUF1778 domain-containing protein	NA	NA	NA	NA
AYY24845.1\|23332_23536_+	hypothetical protein	NA	NA	NA	NA
AYY24846.1\|23565_23880_+	hypothetical protein	NA	NA	NA	NA
AYY24847.1\|24209_25214_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AYY24848.1\|25653_26406_-	alpha/beta hydrolase	NA	NA	NA	NA
AYY24849.1\|26646_27516_+	DMT family transporter	NA	NA	NA	NA
AYY24850.1\|27649_28873_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
AYY24851.1\|29058_29832_-	SDR family oxidoreductase	NA	NA	NA	NA
AYY24852.1\|29897_30599_-	DsbA family oxidoreductase	NA	NA	NA	NA
AYY24853.1\|30664_31771_-	alkene reductase	NA	NA	NA	NA
AYY25008.1\|31984_32314_+	thioredoxin	V9SJ74	Achromobacter_phage	1.3e-10	34.7
AYY24854.1\|32343_32682_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AYY24855.1\|32686_33268_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AYY24856.1\|33409_33967_-	OsmC family peroxiredoxin	NA	NA	NA	NA
AYY24857.1\|34921_35926_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AYY24858.1\|36399_36852_-	hypothetical protein	NA	NA	NA	NA
AYY24859.1\|38662_39001_-	hypothetical protein	NA	NA	NA	NA
AYY25009.1\|39006_39663_-	hypothetical protein	NA	NA	NA	NA
AYY24860.1\|40498_41398_-	RepB family plasmid replication initiator protein	A0A1B0VDL5	Salmonella_phage	6.9e-67	49.0
AYY24861.1\|41718_42780_-	hypothetical protein	NA	NA	NA	NA
AYY24862.1\|42865_43120_-	hypothetical protein	NA	NA	NA	NA
AYY24863.1\|43296_44433_+	recombinase	NA	NA	NA	NA
AYY24864.1\|44498_44816_-	hypothetical protein	NA	NA	NA	NA
AYY24865.1\|44967_45291_-	hypothetical protein	NA	NA	NA	NA
AYY24866.1\|45287_46046_-	hypothetical protein	NA	NA	NA	NA
AYY24867.1\|46042_47002_-	DNA replication protein	NA	NA	NA	NA
AYY24868.1\|47044_47452_-	hypothetical protein	NA	NA	NA	NA
AYY24869.1\|47461_47926_-	hypothetical protein	NA	NA	NA	NA
AYY24870.1\|47973_48216_-	hypothetical protein	NA	NA	NA	NA
AYY24871.1\|48629_48980_+\|transposase	transposase	Q716C1	Shigella_phage	4.9e-37	93.2
AYY24872.1\|48899_50051_-\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-42	35.6
AYY24873.1\|50992_52069_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AYY24874.1\|53871_54393_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AYY24875.1\|54389_55343_+	fec operon regulator FecR	NA	NA	NA	NA
AYY24876.1\|55429_57754_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
AYY24877.1\|57798_58701_+	Fe(3+)-dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
AYY24878.1\|58697_59696_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
AYY24879.1\|59692_60649_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	NA	NA	NA	NA
AYY24880.1\|60649_61417_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2
AYY24881.1\|61515_61809_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	8.0e-49	95.9
AYY25010.1\|62139_62418_-	EAL domain-containing protein	NA	NA	NA	NA
AYY24882.1\|62679_63684_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
AYY24883.1\|64044_64464_+	DUF2946 domain-containing protein	NA	NA	NA	NA
AYY24884.1\|64546_66610_+	TonB-dependent copper receptor	NA	NA	NA	NA
AYY24885.1\|66666_66927_+	DUF2534 family protein	NA	NA	NA	NA
AYY24886.1\|67023_67362_-	copper resistance protein CopC	NA	NA	NA	NA
AYY24887.1\|68167_68995_+\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
AYY25011.1\|69008_71069_+\|transposase	transposase	NA	NA	NA	NA
AYY24888.1\|71061_72672_+	ATP-binding protein	NA	NA	NA	NA
AYY24889.1\|74168_75791_+\|transposase	transposase	NA	NA	NA	NA
AYY24890.1\|76347_76611_+	hypothetical protein	NA	NA	NA	NA
AYY24891.1\|77026_77599_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
AYY24892.1\|77696_80558_+	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	1.2e-128	41.3
AYY24893.1\|80574_82005_+	cardiolipin synthase	NA	NA	NA	NA
AYY24894.1\|83432_83891_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
AYY24895.1\|83913_84828_+	hypothetical protein	NA	NA	NA	NA
AYY24896.1\|84930_85818_+	hypothetical protein	NA	NA	NA	NA
AYY24897.1\|85914_86526_+	HdeD family acid-resistance protein	NA	NA	NA	NA
AYY24898.1\|87363_88275_+	mechanosensitive ion channel family protein	NA	NA	NA	NA
AYY24899.1\|88271_88463_+	hypothetical protein	NA	NA	NA	NA
AYY24900.1\|88455_89148_+	hypothetical protein	NA	NA	NA	NA
AYY24901.1\|89104_89710_+	hypothetical protein	NA	NA	NA	NA
AYY24902.1\|89699_90140_+	thioredoxin TrxC	A0A023NHA9	Dinoroseobacter_phage	6.9e-12	35.6
AYY24903.1\|90143_91850_+	sodium:proton exchanger	NA	NA	NA	NA
AYY24904.1\|92626_92869_+	diguanylate cyclase	NA	NA	NA	NA
AYY24905.1\|92880_93369_+	diguanylate cyclase	NA	NA	NA	NA
AYY24906.1\|93355_94318_+\|protease	Zn-dependent protease	NA	NA	NA	NA
AYY25012.1\|94337_95489_+	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.7e-25	30.2
AYY24907.1\|96202_97126_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	2.7e-167	94.1
AYY24908.1\|97527_98514_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AYY24909.1\|98639_98945_+	hypothetical protein	NA	NA	NA	NA
AYY24910.1\|100812_103464_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.6e-151	34.0
AYY24911.1\|106201_106486_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	6.4e-19	54.8
AYY24912.1\|106475_106724_-	plasmid stabilization protein	NA	NA	NA	NA
AYY24913.1\|106968_107892_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	5.1e-166	94.1
AYY24914.1\|108115_109714_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	4.0e-17	36.4
AYY24915.1\|110172_111306_+	aldehyde dehydrogenase	E3SJ82	Synechococcus_phage	9.7e-10	28.8
AYY24916.1\|112486_113638_+\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-42	35.6
AYY24917.1\|114302_115802_-	kinase	NA	NA	NA	NA
AYY24918.1\|115829_117563_-	protein phosphatase 2C domain-containing protein	NA	NA	NA	NA
AYY25013.1\|117562_118603_-	VWA domain-containing protein	NA	NA	NA	NA
AYY24919.1\|118695_119334_-	VWA domain-containing protein	NA	NA	NA	NA
AYY24920.1\|119334_119976_-	TerD family protein	A0A2P1N0C0	Streptomyces_phage	2.4e-05	25.1
AYY24921.1\|120000_120639_-	VWA domain-containing protein	NA	NA	NA	NA
AYY24922.1\|121118_121577_-	tellurium resistance protein TerW	NA	NA	NA	NA
AYY24923.1\|121579_122803_-	DUF4236 domain-containing protein	NA	NA	NA	NA
AYY24924.1\|122813_123770_-	citrate lyase subunit beta	NA	NA	NA	NA
AYY24925.1\|123769_124849_-	hypothetical protein	A0A172Q0S8	Acinetobacter_phage	1.7e-40	34.1
AYY24926.1\|124850_125624_-	hypothetical protein	NA	NA	NA	NA
AYY25014.1\|125616_126759_-	adenine/guanine phosphoribosyltransferase	A0A172Q0Y1	Acinetobacter_phage	1.8e-32	27.9
AYY24927.1\|126770_127829_-	carbamoyl-phosphate synthase large chain	NA	NA	NA	NA
AYY24928.1\|128140_128725_+	tellurium resistance protein TerZ	K4JRX3	Caulobacter_phage	4.1e-12	29.9
AYY24929.1\|128721_129873_+	tellurium resistance protein TerA	NA	NA	NA	NA
AYY24930.1\|130364_131405_+	tellurium resistance membrane protein TerC	K7QKE8	Escherichia_phage	1.8e-71	46.5
AYY24931.1\|131443_132022_+	TerD family protein	K4JRX3	Caulobacter_phage	1.9e-33	40.8
AYY24932.1\|132108_132684_+	TerD family protein	K4JRX3	Caulobacter_phage	9.6e-30	41.6
AYY24933.1\|132768_134010_+	tellurium resistance protein TerF	A0A2D1GNA9	Pseudoalteromonas_phage	4.8e-10	25.1
AYY24934.1\|134346_134994_-	HAD-IB family hydrolase	NA	NA	NA	NA
AYY24935.1\|135221_135968_-	hypothetical protein	NA	NA	NA	NA
AYY24936.1\|136033_136792_-	hypothetical protein	NA	NA	NA	NA
AYY24937.1\|137024_137756_-	plasmid SOS inhibition protein A	NA	NA	NA	NA
AYY24938.1\|138015_138618_-	hypothetical protein	NA	NA	NA	NA
AYY24939.1\|139610_140882_-	DUF1173 family protein	NA	NA	NA	NA
AYY24940.1\|141064_141514_+	nuclease	A0A0R6PHV6	Moraxella_phage	4.1e-12	36.9
AYY24941.1\|141560_142484_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	4.1e-176	99.0

DBSCAN-SWA_2

149276 : 212302

Enterobacteria_phage(18.52%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYY24947.1\|149276_150200_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	4.7e-172	97.1
AYY24948.1\|150320_150674_+	hypothetical protein	NA	NA	NA	NA
AYY24949.1\|150793_151867_+	aromatic acid exporter family protein	NA	NA	NA	NA
AYY24950.1\|151947_152871_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	2.8e-172	97.1
AYY24951.1\|152895_153249_+	hypothetical protein	A0A2H4IBK3	Erwinia_phage	1.7e-24	51.0
AYY24952.1\|153326_153896_+	hypothetical protein	G8C7Q8	Escherichia_phage	6.8e-28	42.4
AYY24953.1\|153904_154363_+	hypothetical protein	G8C7Q9	Escherichia_phage	5.1e-42	55.0
AYY24954.1\|154449_155418_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	1.9e-179	96.6
AYY24955.1\|155486_155702_+	hypothetical protein	NA	NA	NA	NA
AYY24956.1\|157576_158113_+	plasmid transfer protein	NA	NA	NA	NA
AYY24957.1\|160419_161430_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	1.1e-86	53.5
AYY24958.1\|161459_161741_+	hypothetical protein	NA	NA	NA	NA
AYY24959.1\|161955_162204_-	hypothetical protein	NA	NA	NA	NA
AYY24960.1\|162159_163326_+	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	7.5e-223	97.2
AYY24961.1\|163325_164297_+	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	1.0e-148	86.6
AYY24962.1\|167866_168310_+	DUF2384 domain-containing protein	NA	NA	NA	NA
AYY24963.1\|168306_168777_+	RES domain-containing protein	NA	NA	NA	NA
AYY24964.1\|168908_169832_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	1.0e-166	93.2
AYY24965.1\|169951_170212_-	hypothetical protein	NA	NA	NA	NA
AYY24966.1\|170912_172281_+\|transposase	IS3-like element ISKpn8 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	7.2e-108	95.5
AYY24967.1\|173225_174149_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	6.9e-171	96.4
AYY24968.1\|174487_175699_-	M24 family metallopeptidase	NA	NA	NA	NA
AYY24969.1\|175785_176739_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.7e-10	24.0
AYY24970.1\|176895_177744_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AYY24971.1\|177767_178439_+	amino acid ABC transporter permease	NA	NA	NA	NA
AYY24972.1\|178435_179098_+	amino acid ABC transporter permease	NA	NA	NA	NA
AYY24973.1\|179102_179921_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.8e-29	38.3
AYY24974.1\|179917_180883_+	DMT family transporter	NA	NA	NA	NA
AYY24975.1\|182836_183760_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	4.7e-172	97.1
AYY25015.1\|184452_185361_+	HNH endonuclease	NA	NA	NA	NA
AYY24976.1\|185748_186099_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	1.9e-20	54.3
AYY24977.1\|186242_186674_-	silver-binding protein SilE	NA	NA	NA	NA
AYY24978.1\|186924_188400_-	Cu(+)/Ag(+) sensor histidine kinase	W8CYF6	Bacillus_phage	1.0e-27	30.1
AYY24979.1\|188392_189073_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.1e-31	36.0
AYY24980.1\|189262_190648_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
AYY24981.1\|190676_191030_+	copper ABC transporter substrate-binding protein	NA	NA	NA	NA
AYY24982.1\|191143_192436_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
AYY24983.1\|192446_195593_+	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	4.0e-61	22.5
AYY24984.1\|195679_196120_+	hypothetical protein	NA	NA	NA	NA
AYY24985.1\|196246_198694_+	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	4.4e-84	35.8
AYY24986.1\|198734_198932_+	DUF2933 domain-containing protein	NA	NA	NA	NA
AYY24987.1\|198965_199703_-	peptidase	A0A2H4JAF5	uncultured_Caudovirales_phage	1.3e-10	31.9
AYY24988.1\|199991_200441_-	copper resistance protein	NA	NA	NA	NA
AYY24989.1\|200674_202492_+	multicopper oxidase PcoA	NA	NA	NA	NA
AYY24990.1\|202491_203388_+	copper resistance protein B	NA	NA	NA	NA
AYY24991.1\|203427_203808_+	copper resistance system chaperone PcoC	NA	NA	NA	NA
AYY24992.1\|203812_204742_+	copper resistance protein D	NA	NA	NA	NA
AYY24993.1\|204796_205477_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.7e-30	34.4
AYY24994.1\|205473_206874_+	sensor histidine kinase	W8CYF6	Bacillus_phage	4.1e-18	26.3
AYY24995.1\|207089_207524_+	copper-binding protein	NA	NA	NA	NA
AYY24996.1\|208029_208434_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	2.1e-68	97.0
AYY24997.1\|208430_208778_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
AYY24998.1\|208826_210365_+\|transposase	IS66-like element ISKpn24 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.0e-279	94.1
AYY24999.1\|210416_211355_-	LysR family transcriptional regulator	NA	NA	NA	NA
AYY25016.1\|211387_212302_-	alpha/beta hydrolase	A0A1D8EVD1	Mycobacterium_phage	9.0e-06	28.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP033755

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5899 : 12942

Escherichia_phage(50.0%)

integrase

attL 2746:2758|attR 6799:6811

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2746:2758	attL	NA	NA	NA	NA
AYY19697.1\|5899_6694_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.5e-52	88.7
AYY19698.1\|7173_7353_-	Par-like protein	NA	NA	NA	NA
6799:6811	attR	NA	NA	NA	NA
AYY19806.1\|7472_8099_-	cobyrinic acid ac-diamide synthase	A0A222YXS3	Escherichia_phage	2.9e-40	43.6
AYY19699.1\|8747_9623_-	RepB family plasmid replication initiator protein	Q71TL8	Escherichia_phage	5.6e-82	56.4
AYY19700.1\|10034_11306_-	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	5.2e-153	64.0
AYY19701.1\|11305_11737_-	peptidase	A0A1W6JNS2	Morganella_phage	2.1e-29	53.3
AYY19702.1\|11970_12942_+	StbA family protein	A0A222YXF2	Escherichia_phage	1.1e-73	46.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP033756

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP033758

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP033755

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection