CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP033932	Chryseobacterium bernardetii strain G0229 chromosome, complete genome	4 crisprs	DEDDh,WYL,cas3,PD-DExK,csa3,cas1,cas9,c2c10_CAS-V-U3	0	1	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP033932_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033932_1

1205474-1205572

Orphan

Consensus_repeat	Method
TTTATTATCTTATTGAAAATGATTAAGTTTGTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033932_1

>merge|CP033932|1|1205474-1205572|CRISPRCasFinder
TTTATTATCTTATTGAAAATGATTAAGTTTGTTATTCTTAAATGATTTTATTGGCAGAAAAAAATTTATTATCTTATTAAAAATGATTAAGTTTGTTAT

>CP033932|1|1|1205474-1205572|CRISPRCasFinder
TTTATTATCTTATTGAAAATGATTAAGTTTGTTAT	TCTTAAATGATTTTATTGGCAGAAAAAAA
TTTATTATCTTATTAAAAATGATTAAGTTTGTTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP033932.1\|AZB27559.1\|1202837_1205372_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
CP033932.1\|AZB24140.1\|1202680_1202872_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB24141.1\|1205587_1205812_+\|uroporphyrinogen-decarboxylase	unknown	unknown	unknown
CP033932.1\|AZB24134.1\|1197025_1198294_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB24137.1\|1200167_1200521_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275063
CP033932.1\|AZB24147.1\|1212435_1213026_+\|transcription-elongation-protein-SprT	unknown	unknown	gnl\|CDD\|179886
CP033932.1\|AZB24139.1\|1201994_1202522_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB24146.1\|1211111_1212434_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
CP033932.1\|AZB24138.1\|1200605_1201793_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
CP033932.1\|AZB24142.1\|1205811_1206924_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
CP033932.1\|AZB24135.1\|1198429_1199326_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB24144.1\|1208412_1209297_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133027
CP033932.1\|AZB27560.1\|1207490_1208408_+\|lipopolysaccharide-heptosyltransferase-family-protein	unknown	unknown	gnl\|CDD\|340821
CP033932.1\|AZB24132.1\|1195906_1196179_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379083
CP033932.1\|AZB24149.1\|1214143_1214809_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB24143.1\|1207020_1207440_+\|SufE-family-protein	unknown	unknown	gnl\|CDD\|376883
CP033932.1\|AZB24133.1\|1196235_1196979_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225818
CP033932.1\|AZB24136.1\|1199438_1200146_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226728
CP033932.1\|AZB24148.1\|1213058_1214111_+\|mannose-1-phosphate-guanylyltransferase	unknown	unknown	gnl\|CDD\|133003
CP033932.1\|AZB24145.1\|1209683_1210928_-\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl\|CDD\|223362

Protein	Function_ID	Function_description	E-value
CP033932.1\|AZB27559.1\|1202837_1205372_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
CP033932.1\|AZB24137.1\|1200167_1200521_+\|hypothetical-protein	gnl\|CDD\|275063	TIGR04222, integral_membrane_protein, TIGR04222 domain. The majority of the proteins with a domain as described by this model have an extreme C-terminal sequence that is consists of extremely low-complexity sequence, rich in Ser or in Gly interspersed with Cys. That C-terminal region resembles ribosomal natural product precursors, although there is no evidence that C-terminal regions of these proteins undergo any modification or have any such function.	1.88738e-05
CP033932.1\|AZB24147.1\|1212435_1213026_+\|transcription-elongation-protein-SprT	gnl\|CDD\|179886	PRK04860, PRK04860, SprT family zinc-dependent metalloprotease.	4.48217e-06
CP033932.1\|AZB24146.1\|1211111_1212434_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	2.29231e-47
CP033932.1\|AZB24143.1\|1207020_1207440_+\|SufE-family-protein	gnl\|CDD\|376883	pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export).	2.45466e-63
CP033932.1\|AZB24142.1\|1205811_1206924_+\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.41303e-22
CP033932.1\|AZB27560.1\|1207490_1208408_+\|lipopolysaccharide-heptosyltransferase-family-protein	gnl\|CDD\|340821	cd03789, GT9_LPS_heptosyltransferase, lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	1.85951e-34
CP033932.1\|AZB24144.1\|1208412_1209297_+\|glycosyltransferase	gnl\|CDD\|133027	cd04184, GT2_RfbC_Mx_like, Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.	3.43999e-11
CP033932.1\|AZB24132.1\|1195906_1196179_+\|hypothetical-protein	gnl\|CDD\|379083	pfam13239, 2TM, 2TM domain. This short region contains two transmembrane alpha helices that are found associated with a wide range of other domains. This domain may be involved in cell lysis or peptidoglycan turnover.	1.11421e-06
CP033932.1\|AZB24138.1\|1200605_1201793_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
CP033932.1\|AZB24133.1\|1196235_1196979_+\|DNA-binding-response-regulator	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	1.26756e-31
CP033932.1\|AZB24136.1\|1199438_1200146_+\|hypothetical-protein	gnl\|CDD\|226728	COG4278, COG4278, Uncharacterized conserved protein [Function unknown].	1.12541e-34
CP033932.1\|AZB24148.1\|1213058_1214111_+\|mannose-1-phosphate-guanylyltransferase	gnl\|CDD\|133003	cd02509, GDP-M1P_Guanylyltransferase, GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose. GDP-mannose-1-phosphate guanylyltransferase, also called GDP-mannose pyrophosphorylase (GDP-MP), catalyzes the formation of GDP-Mannose from mannose-1-phosphate and GTP. Mannose is a key monosaccharide for glycosylation of proteins and lipids. GDP-Mannose is the activated donor for mannosylation of various biomolecules. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase and mannose-1-phosphate guanylyltransferase. This CD covers the N-terminal GDP-mannose-1-phosphate guanylyltransferase domain, whereas the isomerase function is located at the C-terminal half. GDP-MP is a member of the nucleotidyltransferase family of enzymes.	2.74417e-123
CP033932.1\|AZB24145.1\|1209683_1210928_-\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl\|CDD\|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	3.16834e-119

>CP033932.1|AZB27559.1|1202837_1205372_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MDYKFSQGLSQVFKQSKSEAKRLKSEFLNTEHLLLGIIKTENSAKEILQNLNADLTQIRRKIETLNTASLNPISEEVTNISFTKMADHAIKRAELECRQYKSNEINTVHLLLGILYKYEDPTSNILGAYDIDYEGVSREYQTMLKNSGQSPQMSAYDDDDEREEFEQMRKPTGNLGSAKSKTPTLDNFGRDLTSLARDGKLDPVIGREKEIERVSQILSRRKKNNPLLIGEPGVGKSAIAEGLALRIQQKKVSRVLYGKRVITLDLASLVAGTKYRGQFEERMKAIMTELEKNRDVILFIDELHTIVGAGSSTGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALERRFQKVMVEPTSIEETIQILNQIKDKYEEHHNVIYTPEAIAACVNLTSRYITDRFLPDKAIDAMDEAGSRVYIKNMKVPTEIIDFEKKIEEIKELKQKAVKAQDYLEARKLKDEEERLQMELNAAQEKWDKDVKEKKETVTEENVAEVVSMMSGVPVTKVGKNELDKLANMDGKLNGKVIGQEDAVKKVVKAIQRNRAGLKDPNRPIGTFIFLGTTGVGKTELAKVMARELFDSDEALIRIDMSEYMEKFAVSRLVGAPPGYVGYEEGGQLTEAVRRKPYAVVLLDEIEKAHPDVFNILLQILDEGHVTDSLGRKIDFRNTIIILTSNIGTRDLKDFGDGVGFGTSAKKSTSDTRARSTIENALKKAFAPEFLNRIDDIIIFNSLVQDDIKKIIDIELNKLYGRLEKLGYKVELTDEAKDFISEKGWDKDFGARPLKRAIQKYIEDLLAEMLVNKQLNEGETVVLDLNEAKDGLVGKTSKPKKSSAAEKSS
>CP033932.1|AZB24140.1|1202680_1202872_+|hypothetical-protein
MLTITMLVFIEMEFSSSYKKDNIKLALVQTYIKAKTPGISRCFLLKFNYLFNIKKISQQLKTS
>CP033932.1|AZB24139.1|1201994_1202522_+|hypothetical-protein
MKKFIISIMLIVSGSAFSQVSIGTPVQENNRWTFGGGIGLGFGSNSSFYLQASPRVGYRLTEDLEAGAVGSVSWQTSDYYRSTMFGIGPFANYYIARSFYLSANFQHYFINYKDKYYDYKYNREENALYLGGGYMQRIGNNSFMQIGLMYNVLWKENSSVFSNGLVPNIGFVVGL
>CP033932.1|AZB24138.1|1200605_1201793_-|tRNA-2-thiouridine(34)-synthase-MnmA
MKIVVGLSGGVDSSVTAYLLQQQGHDVVALFMRNWNDASVTLEDECPWIEDSNDALMVAQKLGIPFQVIDMSELYKERIVDYMFAEYEKGRTPNPDVLCNREVKFDVFMKTAMSLGADKVATGHYARVHSTIDENGKEIFHLLAGKDNNKDQSYFLCQLSQDQLSKALFPIGELTKPQVREIAKEIGLVTADKKDSQGLCFIGKVSLPQFLQQQLKPNEGEIVEIFKDSPLFAEETPEFSTKEEELQFLSRKINYKKADGKVIGKHQGAQFFTIGQSKGLGIGGHKESCFIVSRDMENNILFVGEGSHFPGLYKKALKIDNSELHWVREDLRLRNGETMEVMARFRYRQPLQKATLYQFEDAFYIEFEEPQSAIAEGQFASWYIDEELIGSGVIS
>CP033932.1|AZB24137.1|1200167_1200521_+|hypothetical-protein
MKKLIIHSIPVVISCIWLVAEFQTFNPIPLKGTEFLKFYSILIVGFYISIFIVKSRKEIISRVTIYFTILILGVGIIKLIRGIILGKPIGFLVMILMAESIAVFLLMSWKLNDKIKQ
>CP033932.1|AZB24136.1|1199438_1200146_+|hypothetical-protein
METKMLLKDESLWNRIQGFSLDASDADFPFSKKLAKEENWSLEFTRKAIEEYKKFVYLCCILPKGASPSEIVDKVWHLHLIYTQNYWEEFCPKILKRPLHHHPSKGGFNEKLKHQNWFTDTLKSYQDIFQAEAPRDIWLNRNTIDKTKNKLRIGKFIPFLMLILLLTSCLGEVITTIGSIFFSFVGILVFGGVIASIKKFKDKNDGNSDSSCGGSSCSGGGGCGGGCGGCGGCGG
>CP033932.1|AZB24135.1|1198429_1199326_-|hypothetical-protein
MKKDDILHLEKLMNFLSRQFLKKNHWEDVTKTEWSYICAELNELIITEYSEKEIKKKPDLLGNNYLYEHLIINKLKKFRQNENAVLSRPNLAKLSLIVKVLGYSNYIDFINSNTESFNFNDLKIDMNNVKPNITLLERLVGCWYSYNRNLPENPTQAREDRIWRSAMEIYKSETTGEYFIERSGGDHHKYFGKVTAYSDYVFIIMNSNTFIRQRHFISRIKDSKEKLKNPDYKLHELHFISTCISFNQEPIALFEIFLKADRKNFISDSISFPIDSDEIPESILKQLEDTESNRIDYR
>CP033932.1|AZB24134.1|1197025_1198294_-|hypothetical-protein
MEYYELYDVLKSHFDSRKGIVKIKDLNVTIESIPFESRVCHLAYGSDNTDCTEHHHPLKINENAYLIYHQPSIDIKDFDIECNKRFEYHILKRADVETANGCIIFFHGLNEKKWDKYLPWAYELAQKTGKAVILFPIAFHMDRAEAIWSDRHQMTEIVKFRKEKYPENTHFSYVNAATSSRLEAHPQRVFWSGLQTYSDIIEVVKDIKSDKIKGISPDASLDLFGYSIGSFLSMIIKMADPHGFFTQSKVFCFCGGMTIDRMFPISKYIMDSQATIKMQSVFTELLSSDFKYDNRLKHYQDDELHPQESWFKKMLRYNYFQKEREERIHEIQSQIKAYVLEKDSIAPPMEALNTLRGGYRNINVDVEIRDFPFDYSHMVPFPLTHKHKTEITEAFHQFIKSASDFYSRPSGVENGEEKPEKK
>CP033932.1|AZB24133.1|1196235_1196979_+|DNA-binding-response-regulator
MIKTVIIEDEKPASRKLERMLGSFPDIEVVAKIESVEEGVAWFSENEHPQLIFSDIVLGDGLSFDIFEKVPTKGFIIYTTAFDQYTLKAFKLNSIDYLLKPILEEDLSGAIEKFKSFLPSNSDIGSQDIKQLIRKEKSILSRVLVKIGYNLKIVQTQEISCFFSENKIVYLQTDERSYPSDFTLDELADILDDKKFFRVNRQFIINSDYIKNIHTSPYYKVDLEFQPQEEITVSRDRVKDFKDWLVS
>CP033932.1|AZB24132.1|1195906_1196179_+|hypothetical-protein
MDYNNAYNRVQQLKKFYKNLIWFGIVSAIIIGNDWFNDELHYRIFGGHLFLAIWALFLGIKAVSLFIFNDEWEKEMMRKETQKNKKAIDF
>CP033932.1|AZB24141.1|1205587_1205812_+|uroporphyrinogen-decarboxylase
MNPEITTYIGYSASVFIVLSFILKDVRKIRVVNMIGCICFVIYGFFSGPLWPVIIPNGLICFIQVYHLLLGKKA
>CP033932.1|AZB24142.1|1205811_1206924_+|glycosyltransferase
MKKKIIISAFSNLYTDQRIEKICRTLYENGYEIDLIGNDWNGAEEIQRPYSFSRIHLASKSLKTAYLEFNWKLYHILKKKADQNTILHANDIDALYPNYLIARKLNIPLVFDSHEIFSEMPAVQGKMSQKLWRYVEKTVIPNLKWMITASGSYGKWFEKKYGIDPVIVQNAPREIGFTDDLPENNPKILLYQGAVNPFRGIDKVILAMHYLDHVQLKIAGDGPRKKEYEELVIREKLEHKVQFLGKLKPEDLRKVTLTADCGMSIEENGGESYLYSLPNKVLDCIQARVPLILSNLPELKNIKDQFDVGELIKDHQPENIAAAVNKVLAKGRGNYQLELEKAAKVLRWENEEIKLLQVFRKASNASGFKG
>CP033932.1|AZB24143.1|1207020_1207440_+|SufE-family-protein
MTIKEKQQEIIDEFAFLDDWEQKYEYIIDLGKELKGLPDDKKTEENLIKGCQSKVWIDAEFKDGKLFFNADSDGILPKGIVSLLVSIYSGHSTQEILDSDFEFISEIGLQEFLSPSRANGLMAMTKQIKFYAVAYQLKS
>CP033932.1|AZB27560.1|1207490_1208408_+|lipopolysaccharide-heptosyltransferase-family-protein
MTVPVFKEFLEQNPGVEIVMVSRKNFEALFAGIPNVIFKGINVDDYKGFFGLRKLGDELIKEFKPDYIANLHDVIRTKILDRIYRRKGLKVFKIDKGKEEKEHLTDVWNLNKVQLKKTVERYADVFREMGFKVELSQKLRPVSEHKSGIGFAPFAQHKGKMLPLEKSFELARLLAQKHTVYFFGGGKKETETLESWESKIPNTKSLSGKLSLTEELQKISELEVMISMDSANMHLASLMGTRCVSIWCETHPYAGFLGFGQSEEDVVQVKDLSCRPCSVFGDKECYRGDWACLEEFTIQKVIEKI
>CP033932.1|AZB24144.1|1208412_1209297_+|glycosyltransferase
MKLSICIPVYNFDVRELVFDLKKEIDSQKIDAEIILIDDASDAAFKSINEELQDQVEKLVFLNKNIGRSRIRNLFLQYSLGEYLLFLDCDVKIPGKRFLWNYISEINKHPDLELIYGSFTIDPKYASTLRNRYSVEREIFSGNRSYDFALFKTVNFIISKKILEKFPFDETLTEYGYEDFVFAKLLEQNEVKFLAMANPVIHIDDTNNAIFLGKAEIGMESLFRLSKNPINKAFIKDIKVYKAAVILKRLGLIPLFLSIYKILEEKIRTNLLSGNPNIRYFDFYKLNVLARKMK
>CP033932.1|AZB24145.1|1209683_1210928_-|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MTNEQYQEAIDWLFVQMPNYQIDGQKAYKPGLDNITKLCAYFGNPQDKIKCIHIGGTNGKGSSSNMLASVLQEVGYKVGLYNSPHLIDFTERIKVNGKNCHKEFVFDFIQKLKNIPEDIRPSFFEFTTIMAFEYFYQQQVDYAIIEVGLGGRLDSTNIIKPLASAITNVQLDHQNILGDTIEEIAAEKAGIIKKSVPIISGDENEAVKAIIREKAMKEEASFIDATLLHTDLASDLKGNYQRKNIRVVLSIIEELRKQGINITDKNVENGLLNVHKNTGFIGRWFEFSKDPLTICDTGHNQAGLEYVFSQLNSINRRKHVILGFVNDKKIDEVMNLLPENSEFYFAKPSINRGRHPEDYEKLLQEAKIFYKIFNSVQEAYLSAKERCTSEEMIFIGGSNFIVGDFLEKNLEFKE
>CP033932.1|AZB24146.1|1211111_1212434_+|TolC-family-protein
MKKVWIIVFGLGSLGLSAQKKWSLKECVSYAVEHNLQVIQNQYTKQNQEYNLKAAKKDYLPSVSGSMMNGVSFGQGSLGAGSYRNDRFNNSVGVSADVLVYNNGRLEKNVRKLQFDVEASQYDIEAIKNDISVQIAQQYLTALLNKEIVKISQSAVENAKKQYDRAKITTQVGTTAQTVLAEAEAALAREKQNLKTAEVNVGRALFAIAQLLQLSDYKDFDVENVDVPEALDSQLVTADEVLTKAYDVQPQIKAAESRIRSAEAQTEVSKTAFWPTLTASAGLNTFYNKSFNVPPGVVQGTFFEQYKDQFGQNVGLSLNIPIFNKGKTKLQVEQSKLNESVSKISLEQQKQAVRQNIQKAQFDADANYESYLAALEAEKSSKLALDFADKSYAAGKTTIYDVNVARNNYANAQGSVAQAKYNYLFSLKLLNFYAGIPLSL
>CP033932.1|AZB24147.1|1212435_1213026_+|transcription-elongation-protein-SprT
MSIQSLEKYLPQNTLKYLKIWFSDYYIHIKVTRNRNSKLGDYRKLPDNSHEITVNSTLTPQLFFFVLTHELAHMIAFEKYGRRISPHGNEWKETFRNMLLESLEIYDEDLKPIIVKFSKSPKANFMASPDLVRYFHTEKQDDRLYFIEQLQKGEFFIYRNEKYLLEGLIKKNYLCKNLATGRKYSFKPLARVEKCS
>CP033932.1|AZB24148.1|1213058_1214111_+|mannose-1-phosphate-guanylyltransferase
MAGGIGSRFWPMSTQKFPKQFQDILGTGRTMIQQTYDRISKIIPKEHIFVITNKEYVALSHQQLPEIPEENIVGEPLMKNTAACNLYMANKIAEINPNATMIVLPADHLILKEDVFLEKVMLAFDLASKHDYLVTLGITPTRPDTGYGYIQFVEKKNSEYFKVKIFTEKPILEIAQSFLESGDFLWNAGIFIWNIKSIQHAFEMYLPEMTQHFMACEYNSEKENSCIETIYPKVQKISIDNGILEKAKNVYVIPSDLGWSDLGTWTSVYENTEKDKDGNAVKLKHLLAYNSKGNIIRLKNNNKAVIIDGLENYIVVDTDKALLICPRDNDQLIKDYVLDLKNFKKGDKFM
>CP033932.1|AZB24149.1|1214143_1214809_+|hypothetical-protein
MIKFALRFTTLILLLFTILGYAQDKKKFSSIPNILQRIEPGANVDSWVLVYNNYGKGEEIKISGGKINYTPQFSGFNLFPSEDSFYYIAYSSGGKINYILDTEALKTFVGKIDNAQEAAIILAADGYMVDEEFKDLAGNYHEDQKNYYLDLGKLTSQECPYQKTHYTLTVNKATGLVTNVKDNGTYIELYNKKCANNPRLLKVEKKEEPKKDESSKTSKRR

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Crispr_ID: CP033932_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033932_4

2615345-2615425

Orphan

Consensus_repeat	Method
TTCGGAATTGCACTCATTCCAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033932_4

>merge|CP033932|4|2615345-2615425|CRISPRCasFinder
TTCGGAATTGCACTCATTCCAAAATGTGGGTTTTCTCGGAATTGCGCTCATTTCGATTTCGGAATTGTACTCATTTTAAAT

>CP033932|4|4|2615345-2615425|CRISPRCasFinder
TTCGGAATTGCACTCATTCCAAAA	TGTGGGTTTTCTCGGAATTGCGCTCATTTCGAT
TTCGGAATTGTACTCATTTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP033932.1\|AZB25275.1\|2616703_2616880_-\|histone-H1	unknown	unknown	unknown
CP033932.1\|AZB25270.1\|2612846_2613098_+\|DUF3853-family-protein	unknown	unknown	gnl\|CDD\|372411
CP033932.1\|AZB25280.1\|2619173_2619725_+\|PRTRC-system-protein-E	unknown	unknown	gnl\|CDD\|274758
CP033932.1\|AZB25266.1\|2608858_2610517_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP033932.1\|AZB25282.1\|2620038_2621202_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25277.1\|2617950_2618160_+\|addiction-module-toxin-RelE	unknown	unknown	unknown
CP033932.1\|AZB25271.1\|2613101_2613737_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379352
CP033932.1\|AZB25264.1\|2607656_2608085_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25267.1\|2610568_2611414_+\|RteC-protein	unknown	unknown	gnl\|CDD\|378161
CP033932.1\|AZB25274.1\|2615573_2616407_+\|DNA-primase	unknown	unknown	gnl\|CDD\|128681
CP033932.1\|AZB25268.1\|2612015_2612279_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|378935
CP033932.1\|AZB25278.1\|2618172_2618652_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375832
CP033932.1\|AZB25283.1\|2621211_2621934_+\|PRTRC-system-protein-B	unknown	unknown	gnl\|CDD\|373078
CP033932.1\|AZB25269.1\|2612295_2612850_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25279.1\|2618708_2619140_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25273.1\|2614057_2615155_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25281.1\|2619742_2619961_+\|PRTRC-system-protein-C	unknown	unknown	gnl\|CDD\|316934
CP033932.1\|AZB25276.1\|2617539_2617938_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
CP033932.1\|AZB25272.1\|2613776_2613998_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25265.1\|2608298_2608547_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP033932.1\|AZB25283.1\|2621211_2621934_+\|PRTRC-system-protein-B	gnl\|CDD\|373078	pfam14460, Prok-E2_D, Prokaryotic E2 family D. A member of the E2/UBC superfamily of proteins found in several bacteria. Members of this family lack the conserved histidine of the classical E2-fold. However, they have an absolutely conserved histidine carboxyl-terminal to the conserved cysteine. Members of this family are usually present in a conserved gene neighborhood with genes encoding members of the Ub modification pathway such as the E1, Ub and JAB proteins. These neighborhoods also contain a gene encoding a rapidly diverging alpha-helical protein.	1.52519e-35
CP033932.1\|AZB25278.1\|2618172_2618652_+\|hypothetical-protein	gnl\|CDD\|375832	pfam18406, DUF1281_C, Ferredoxin-like domain in Api92-like protein. This domain has a ferredoxin like fold. It is often found to the C terminus of pfam06924.	7.48852e-11
CP033932.1\|AZB25270.1\|2612846_2613098_+\|DUF3853-family-protein	gnl\|CDD\|372411	pfam12964, DUF3853, Protein of unknown function (DUF3853). A family of uncharacterized proteins found by clustering human gut metagenomic sequences.	4.93759e-16
CP033932.1\|AZB25276.1\|2617539_2617938_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	9.61162e-23
CP033932.1\|AZB25266.1\|2608858_2610517_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	0.000247296
CP033932.1\|AZB25267.1\|2610568_2611414_+\|RteC-protein	gnl\|CDD\|378161	pfam09357, RteC, RteC protein. Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.	9.53951e-78
CP033932.1\|AZB25281.1\|2619742_2619961_+\|PRTRC-system-protein-C	gnl\|CDD\|316934	pfam14454, Prok_Ub, Prokaryotic Ubiquitin. A Ubiquitin-superfamily protein that is present across several bacterial lineages, and found in gene neighborhoods with components of the ubiquitin modification system such as the E1, E2 and JAB proteins, and a novel alpha-helical protein, which is predicted to be enzymatic.	1.02799e-25
CP033932.1\|AZB25274.1\|2615573_2616407_+\|DNA-primase	gnl\|CDD\|128681	smart00400, ZnF_CHCC, zinc finger.	3.57034e-06
CP033932.1\|AZB25271.1\|2613101_2613737_+\|hypothetical-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	0.00275756
CP033932.1\|AZB25268.1\|2612015_2612279_+\|DNA-binding-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.48914e-08
CP033932.1\|AZB25280.1\|2619173_2619725_+\|PRTRC-system-protein-E	gnl\|CDD\|274758	TIGR03741, PRTRC_E, PRTRC system protein E. A novel genetic system characterized by six or seven major proteins, included a ParB homolog and a ThiF homolog, is designated PRTRC, or ParB-Related,ThiF-Related Cassette. It is often found on plasmids. This protein family averages about 150 amino acids in length, but the last third contains low-complexity sequence that complicates sequence comparisons. This model does not include the low-complexity region.	1.85758e-05

>CP033932.1|AZB25273.1|2614057_2615155_+|hypothetical-protein
MANPDKDFRLIRNKFEIKNEIVQERIRVGNRFVDDFIFDDNEAADIPINALRVIFNIISIISNEQFRPEDRPKQLSLFDEEFETDNNIFASIRIRNSKISPSGSTQQVVDAYEFLARFKMGWYKSLNSKGKEIKTFGGLISAPSYDKRGYTTFLVSSYWLKQLLVIPEYNYILYNLVYSVRNNKHIIFAIWLSKIPESGTVLKLSTLNKKFGLNYKTANDFCFKFLKLARISLDKYNSLSFNYQYKGDSIFIFPYKTKMSSDVLMSENSKKTPKITKRLSYFRKRFGLQENEMNQFFHQYRNIPQTRILIEKAFTRFIKICRLKKIQSVTFRGIAFLQEIQKLVIEIYQESRTGKLIPNGYPIIL
>CP033932.1|AZB25272.1|2613776_2613998_+|hypothetical-protein
MSKKEVTISDLKPGQKVCINGMLAEYKGIQKVRIFNLGKADKRVFKGEEVNIFKYYSLADGSKTLKSEKIKLI
>CP033932.1|AZB25271.1|2613101_2613737_+|hypothetical-protein
MYYLELIQRFWDFNRIAKISPTEIAVYLYLLKIGYEKDRYDFKTSDVELAKELGLTRVTIKSSKEKLKNRGLIQFQTSNGLPCYYRLLLDYSFQTEPETKEEKKGTDTENLLEAASLEISPIIEDVANESSIIPSLQEFMSYAKALESYESQLDFSIEKKYKSWVDKGWKNAFNRPISNWKATLKSALPYMNNSNVDNPISLKDIPNIKHP
>CP033932.1|AZB25270.1|2612846_2613098_+|DUF3853-family-protein
MKVINLKTPICDLTVGEFLEILKNVVAEQKYEYGLKGLAKILGCSISKASEIKSSGILDKAIIQKGNIIIIDKEKALKLFAQK
>CP033932.1|AZB25269.1|2612295_2612850_+|hypothetical-protein
MKQSKNIISFFGSFIQDSRMYPSHISLYVSLFQLWSSNKFQNPFRICREELMKLSKIKSFATYHKCINEIHNAGFINYSPSYNSYEGSSIEIIDFETVDKNKNEISLEEKNLQEEKINFSIPMLYEIEMYFNERDVVSEEAYQFYSLYQSKDWRLTNSNPMKCWKSAARNWISKIKNINQNQNL
>CP033932.1|AZB25268.1|2612015_2612279_+|DNA-binding-protein
MAISIITKEDLQQFKIELLEAIKELLQGNTTEQKLWLRTSEVKKMLNISSGTLQNLRINGTLSYSKIGGTLYYNYKDIEKLLKDFKH
>CP033932.1|AZB25267.1|2610568_2611414_+|RteC-protein
MNGQNFKKKVDQLWKDLSTAVDQINRSENDIVIRTEEILMETDASIRQLKDLLRQYQFPDWSNEIYFFKNTKPQFVAVYIYYSKVLAIEASKPYADSQALRSYYENERSNLLYFYNEQRDFISYYRRKSTYLDKKYFVRLKFDFKLKLSPELYSYDEEFSTSHDHIVSQIIANDLLEQYLTNKIDSKESRENSINHIKNLEWTAPKVALIELLYAVHQTKCFNGGHSDLAEIFRWAENSLNIGLGNYHKTFSEIRLRKTDRTKFLSLLQHNFNQYLDDLDL
>CP033932.1|AZB25266.1|2608858_2610517_+|AraC-family-transcriptional-regulator
MTQGQEIQQQSYKEISRLIDSYSENDERAMVFVKMYIDKAKNDHNLKKQIRGYEEAIYYSKETGRKLSYADSAITSASKLNDQDQIARAYAGKGIIYYYNLRQYKKALKEYLIAFKYSKNSKDGYLKNKIIYHLGMIKSYLGYYKYAAVHFEETADFFEKNAKESLDRNIRFNNESGYYNSIYRLSTCYRNLKLYNKEDSLINIGLEKLHNNSEQVIEFGYFQKGRGVQLLRKGRADEALKHFKVSQDILSSNQDYASLTSVYFYIGKLYRSKGNRAESLKYFNKVDSLVNKFWFITPEIRSTYLYLIDDAKKNRNSERKMYYSEKLLKADSIINADFVMLTDKIYSEYDTDNLIEEKKQMIRGHQVILYSFIGAGLVILFFLIWRFRKREKELNARYQEVLEKLNSSKETISFDVIPPASSDEDNLDLYSSEIIEDIKTNLKIFEDEKQFLQPNLTLEIVGKMIGSNRTHLSYVLNVHFDVTFPTYLKALRIRYITNLLVEDTKYLSYKIETLAKICGMANRQIFSAHFLEINSIRPRDFIRMRQEELKKT
>CP033932.1|AZB25265.1|2608298_2608547_-|hypothetical-protein
MKKYISLLSLTAAFLMQSCERTDSVSEITEQKQQSIEIPNNKESSKNADGSSETNGSNNFKTGDDDEPKKDKQHWRIVQDTI
>CP033932.1|AZB25264.1|2607656_2608085_-|hypothetical-protein
MKTFKTGIIEFISYFFILLFCYAAMGKLMDFDEFQTRISESPLLNRFSQFLPYTIIIAEFFIAGLLCYRKTRNIGLIGSLILMLVFTGYIALIISTSDNLPCSCGGILEKMSWHQHLYFNIGCVILSVIALGLNLRYSRPAE
>CP033932.1|AZB25274.1|2615573_2616407_+|DNA-primase
MNCEEIKQKIGIRTVLESFNLFPSKENRRTAFYFAIDREERTPSLSVDFVKNKAFDFGTGKSYDVISIVQQINQCSVSDALKYLAKFDFFLRNDIQKVESNQEVEYEILKTSEIRHFALVQYLTSRRVYEQKDLVKEVHYKMNGKKYFGIGFLNDSGGFEIRNKYSKICLGKKDVTLIKTQNNFDEIAIFEGFFDYLTYRNMEKEQSTDYLILNSTSMLFKIENELKKYDKISLFLDNDSNGKSVKTKIENQYKNVEDCSLIYNGFEDLNKWYCERK
>CP033932.1|AZB25275.1|2616703_2616880_-|histone-H1
MKELIEKINAEFEAFTTEANQQVEKGNKAAGTRARKSALELSKLFKDFRKISVEESKK
>CP033932.1|AZB25276.1|2617539_2617938_+|single-stranded-DNA-binding-protein
MSTIIGRVTKNAEISILKNDKQVVNFSVAINDSYKNKQGEKVEQTTYYNCAYWQSPNVAKSLTKGTLVELSGRTSSNAWIGKDGEIRSGLNFHTSNIKFHGGGKREGVQNFVTEKAQDKKTFAEDTDDDLPF
>CP033932.1|AZB25277.1|2617950_2618160_+|addiction-module-toxin-RelE
MEAQFNFQIKQKKDEREWEDIEVYYVTNCDRITAIRYARNISKIFKSEIRLTQGKEPFRTSGTYIYENN
>CP033932.1|AZB25278.1|2618172_2618652_+|hypothetical-protein
MANRCNNKVTFKGNQASLNQVSDLFRTMIDNESKGKIGQLPDFIQSEYGYFSEIYKDETEECSFHYDTRWSPNIEVLWTIANHFDVEFVLSYEESGCMLLGKTFYENEILKDYCLNQSDFQDCSYNEEENNYQFEGNIYEYKDEIMKILLGRKIAFGQS
>CP033932.1|AZB25279.1|2618708_2619140_+|hypothetical-protein
MKKSIKPTEYLLIKAKSEWDDCDFAIIHISEEWKKIQKNRLKVVKIVENDSDLKWLNYEDVNVEFFKFSKENYPQIEEWLSEKNQFFVVLEKDDLKQLLQPEHDLHNHQMQVFRSGNAIYNAFGKHTSEEFFTEQFSLVELIK
>CP033932.1|AZB25280.1|2619173_2619725_+|PRTRC-system-protein-E
MQTNFFRHIAKMDLTGDLQITLRPTTENCFVLSILLNNERCGDEARKLIPPLNLRGTAEELDNGFFEQITTPLQTASGLMVDMEAFMKQLEEVKKKSAMEKEKSDKDKKEKDAKEKKYKEALQKAEELEKEGKYKDAWTALPKASEYPDFAEIIRSKQDEYSKHLAPNLFTEASDENVPIETI
>CP033932.1|AZB25281.1|2619742_2619961_+|PRTRC-system-protein-C
MLLATLLERVFVLKDNGHEIKLTDPEPKWSVEAVMNFYANTYPILTTAKVSAPQIKDDTIQYKFESVMGTKG
>CP033932.1|AZB25282.1|2620038_2621202_+|hypothetical-protein
MNATKKNYIGKNKVARRKTTRKVTSTIGQVRSLASKTKDLERNSERQTEICTNNNASNGFLRCKFLPKQEEVSHFQDSKKILNTERDFYKSLSKFSKQYGVEPMQTKDFGFPYNLALAIWDIETKMKQANADWNQFKLIRTNEKFHFAKEEQFCTNTSLHFIPVVPLFKMLHDKNYKKNAQLLLSVFSYLYHIANVPYYRQQDSYLYWIYEMHEEWMEQEEEEAREDSQNYWREFKMSKNIGDKIEKKLFNLKNLDFFEQRLNCFKIQNEFDIICHKVAFEAFALYSEYPNTTIFRNKPSSEENPYDDDYSNKAISMDMYISFVANTKGCLYNNIEDSINAEFNEYGSIEEPTIYLPINGTEIPKADFDFENRLFTLMEELHQVLTY
>CP033932.1|AZB25283.1|2621211_2621934_+|PRTRC-system-protein-B
MNNVIDTNKYLGMLYEPKSALVFYESLYKNEMYVEHFDMDRNGNPINAHPLTVNEAKTLAKSLVIDKEIEKAFLKSKGILANNILHINPSQKGSVIWYTKAQERQMYFVKNLEIPSGKAKVPAMLWIADKENLSVFALSNDKRPTENTTLHYAPFFNVYNDGDVCMGNVDIKIQNSTSVEEFIEQWESYFFNSYFSHLVGGHNPIDGNLVNLWKKLLKSNEAFPNEILKKNNKTLKNLLR

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Crispr_ID: CP033932_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033932_3

2615157-2615265

Orphan

Consensus_repeat	Method
TTCGGAATTGCACTCATTCCAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033932_3

>merge|CP033932|3|2615157-2615265|CRISPRCasFinder
TTCGGAATTGCGCTCATTCTGATTTCGGAATTGCGGTAGCTGAAGTTAAAAAAATCTTAAAATATGAAATTTTCAGTTATTGTTTTCGGAATTGCGCTCATTCCAAAAT

>CP033932|3|3|2615157-2615265|CRISPRCasFinder
TTCGGAATTGCGCTCATTCTGATT	TCGGAATTGCGGTAGCTGAAGTTAAAAAAATCTTAAAATATGAAATTTTCAGTTATTGTT
TTCGGAATTGCGCTCATTCCAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP033932.1\|AZB25275.1\|2616703_2616880_-\|histone-H1	unknown	unknown	unknown
CP033932.1\|AZB25270.1\|2612846_2613098_+\|DUF3853-family-protein	unknown	unknown	gnl\|CDD\|372411
CP033932.1\|AZB25280.1\|2619173_2619725_+\|PRTRC-system-protein-E	unknown	unknown	gnl\|CDD\|274758
CP033932.1\|AZB25266.1\|2608858_2610517_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP033932.1\|AZB25282.1\|2620038_2621202_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25277.1\|2617950_2618160_+\|addiction-module-toxin-RelE	unknown	unknown	unknown
CP033932.1\|AZB25271.1\|2613101_2613737_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379352
CP033932.1\|AZB25264.1\|2607656_2608085_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25267.1\|2610568_2611414_+\|RteC-protein	unknown	unknown	gnl\|CDD\|378161
CP033932.1\|AZB25274.1\|2615573_2616407_+\|DNA-primase	unknown	unknown	gnl\|CDD\|128681
CP033932.1\|AZB25268.1\|2612015_2612279_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|378935
CP033932.1\|AZB25278.1\|2618172_2618652_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375832
CP033932.1\|AZB25283.1\|2621211_2621934_+\|PRTRC-system-protein-B	unknown	unknown	gnl\|CDD\|373078
CP033932.1\|AZB25269.1\|2612295_2612850_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25279.1\|2618708_2619140_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25273.1\|2614057_2615155_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25281.1\|2619742_2619961_+\|PRTRC-system-protein-C	unknown	unknown	gnl\|CDD\|316934
CP033932.1\|AZB25276.1\|2617539_2617938_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
CP033932.1\|AZB25272.1\|2613776_2613998_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25265.1\|2608298_2608547_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP033932.1\|AZB25283.1\|2621211_2621934_+\|PRTRC-system-protein-B	gnl\|CDD\|373078	pfam14460, Prok-E2_D, Prokaryotic E2 family D. A member of the E2/UBC superfamily of proteins found in several bacteria. Members of this family lack the conserved histidine of the classical E2-fold. However, they have an absolutely conserved histidine carboxyl-terminal to the conserved cysteine. Members of this family are usually present in a conserved gene neighborhood with genes encoding members of the Ub modification pathway such as the E1, Ub and JAB proteins. These neighborhoods also contain a gene encoding a rapidly diverging alpha-helical protein.	1.52519e-35
CP033932.1\|AZB25278.1\|2618172_2618652_+\|hypothetical-protein	gnl\|CDD\|375832	pfam18406, DUF1281_C, Ferredoxin-like domain in Api92-like protein. This domain has a ferredoxin like fold. It is often found to the C terminus of pfam06924.	7.48852e-11
CP033932.1\|AZB25270.1\|2612846_2613098_+\|DUF3853-family-protein	gnl\|CDD\|372411	pfam12964, DUF3853, Protein of unknown function (DUF3853). A family of uncharacterized proteins found by clustering human gut metagenomic sequences.	4.93759e-16
CP033932.1\|AZB25276.1\|2617539_2617938_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	9.61162e-23
CP033932.1\|AZB25266.1\|2608858_2610517_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	0.000247296
CP033932.1\|AZB25267.1\|2610568_2611414_+\|RteC-protein	gnl\|CDD\|378161	pfam09357, RteC, RteC protein. Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.	9.53951e-78
CP033932.1\|AZB25281.1\|2619742_2619961_+\|PRTRC-system-protein-C	gnl\|CDD\|316934	pfam14454, Prok_Ub, Prokaryotic Ubiquitin. A Ubiquitin-superfamily protein that is present across several bacterial lineages, and found in gene neighborhoods with components of the ubiquitin modification system such as the E1, E2 and JAB proteins, and a novel alpha-helical protein, which is predicted to be enzymatic.	1.02799e-25
CP033932.1\|AZB25274.1\|2615573_2616407_+\|DNA-primase	gnl\|CDD\|128681	smart00400, ZnF_CHCC, zinc finger.	3.57034e-06
CP033932.1\|AZB25271.1\|2613101_2613737_+\|hypothetical-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	0.00275756
CP033932.1\|AZB25268.1\|2612015_2612279_+\|DNA-binding-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.48914e-08
CP033932.1\|AZB25280.1\|2619173_2619725_+\|PRTRC-system-protein-E	gnl\|CDD\|274758	TIGR03741, PRTRC_E, PRTRC system protein E. A novel genetic system characterized by six or seven major proteins, included a ParB homolog and a ThiF homolog, is designated PRTRC, or ParB-Related,ThiF-Related Cassette. It is often found on plasmids. This protein family averages about 150 amino acids in length, but the last third contains low-complexity sequence that complicates sequence comparisons. This model does not include the low-complexity region.	1.85758e-05

>CP033932.1|AZB25273.1|2614057_2615155_+|hypothetical-protein
MANPDKDFRLIRNKFEIKNEIVQERIRVGNRFVDDFIFDDNEAADIPINALRVIFNIISIISNEQFRPEDRPKQLSLFDEEFETDNNIFASIRIRNSKISPSGSTQQVVDAYEFLARFKMGWYKSLNSKGKEIKTFGGLISAPSYDKRGYTTFLVSSYWLKQLLVIPEYNYILYNLVYSVRNNKHIIFAIWLSKIPESGTVLKLSTLNKKFGLNYKTANDFCFKFLKLARISLDKYNSLSFNYQYKGDSIFIFPYKTKMSSDVLMSENSKKTPKITKRLSYFRKRFGLQENEMNQFFHQYRNIPQTRILIEKAFTRFIKICRLKKIQSVTFRGIAFLQEIQKLVIEIYQESRTGKLIPNGYPIIL
>CP033932.1|AZB25272.1|2613776_2613998_+|hypothetical-protein
MSKKEVTISDLKPGQKVCINGMLAEYKGIQKVRIFNLGKADKRVFKGEEVNIFKYYSLADGSKTLKSEKIKLI
>CP033932.1|AZB25271.1|2613101_2613737_+|hypothetical-protein
MYYLELIQRFWDFNRIAKISPTEIAVYLYLLKIGYEKDRYDFKTSDVELAKELGLTRVTIKSSKEKLKNRGLIQFQTSNGLPCYYRLLLDYSFQTEPETKEEKKGTDTENLLEAASLEISPIIEDVANESSIIPSLQEFMSYAKALESYESQLDFSIEKKYKSWVDKGWKNAFNRPISNWKATLKSALPYMNNSNVDNPISLKDIPNIKHP
>CP033932.1|AZB25270.1|2612846_2613098_+|DUF3853-family-protein
MKVINLKTPICDLTVGEFLEILKNVVAEQKYEYGLKGLAKILGCSISKASEIKSSGILDKAIIQKGNIIIIDKEKALKLFAQK
>CP033932.1|AZB25269.1|2612295_2612850_+|hypothetical-protein
MKQSKNIISFFGSFIQDSRMYPSHISLYVSLFQLWSSNKFQNPFRICREELMKLSKIKSFATYHKCINEIHNAGFINYSPSYNSYEGSSIEIIDFETVDKNKNEISLEEKNLQEEKINFSIPMLYEIEMYFNERDVVSEEAYQFYSLYQSKDWRLTNSNPMKCWKSAARNWISKIKNINQNQNL
>CP033932.1|AZB25268.1|2612015_2612279_+|DNA-binding-protein
MAISIITKEDLQQFKIELLEAIKELLQGNTTEQKLWLRTSEVKKMLNISSGTLQNLRINGTLSYSKIGGTLYYNYKDIEKLLKDFKH
>CP033932.1|AZB25267.1|2610568_2611414_+|RteC-protein
MNGQNFKKKVDQLWKDLSTAVDQINRSENDIVIRTEEILMETDASIRQLKDLLRQYQFPDWSNEIYFFKNTKPQFVAVYIYYSKVLAIEASKPYADSQALRSYYENERSNLLYFYNEQRDFISYYRRKSTYLDKKYFVRLKFDFKLKLSPELYSYDEEFSTSHDHIVSQIIANDLLEQYLTNKIDSKESRENSINHIKNLEWTAPKVALIELLYAVHQTKCFNGGHSDLAEIFRWAENSLNIGLGNYHKTFSEIRLRKTDRTKFLSLLQHNFNQYLDDLDL
>CP033932.1|AZB25266.1|2608858_2610517_+|AraC-family-transcriptional-regulator
MTQGQEIQQQSYKEISRLIDSYSENDERAMVFVKMYIDKAKNDHNLKKQIRGYEEAIYYSKETGRKLSYADSAITSASKLNDQDQIARAYAGKGIIYYYNLRQYKKALKEYLIAFKYSKNSKDGYLKNKIIYHLGMIKSYLGYYKYAAVHFEETADFFEKNAKESLDRNIRFNNESGYYNSIYRLSTCYRNLKLYNKEDSLINIGLEKLHNNSEQVIEFGYFQKGRGVQLLRKGRADEALKHFKVSQDILSSNQDYASLTSVYFYIGKLYRSKGNRAESLKYFNKVDSLVNKFWFITPEIRSTYLYLIDDAKKNRNSERKMYYSEKLLKADSIINADFVMLTDKIYSEYDTDNLIEEKKQMIRGHQVILYSFIGAGLVILFFLIWRFRKREKELNARYQEVLEKLNSSKETISFDVIPPASSDEDNLDLYSSEIIEDIKTNLKIFEDEKQFLQPNLTLEIVGKMIGSNRTHLSYVLNVHFDVTFPTYLKALRIRYITNLLVEDTKYLSYKIETLAKICGMANRQIFSAHFLEINSIRPRDFIRMRQEELKKT
>CP033932.1|AZB25265.1|2608298_2608547_-|hypothetical-protein
MKKYISLLSLTAAFLMQSCERTDSVSEITEQKQQSIEIPNNKESSKNADGSSETNGSNNFKTGDDDEPKKDKQHWRIVQDTI
>CP033932.1|AZB25264.1|2607656_2608085_-|hypothetical-protein
MKTFKTGIIEFISYFFILLFCYAAMGKLMDFDEFQTRISESPLLNRFSQFLPYTIIIAEFFIAGLLCYRKTRNIGLIGSLILMLVFTGYIALIISTSDNLPCSCGGILEKMSWHQHLYFNIGCVILSVIALGLNLRYSRPAE
>CP033932.1|AZB25274.1|2615573_2616407_+|DNA-primase
MNCEEIKQKIGIRTVLESFNLFPSKENRRTAFYFAIDREERTPSLSVDFVKNKAFDFGTGKSYDVISIVQQINQCSVSDALKYLAKFDFFLRNDIQKVESNQEVEYEILKTSEIRHFALVQYLTSRRVYEQKDLVKEVHYKMNGKKYFGIGFLNDSGGFEIRNKYSKICLGKKDVTLIKTQNNFDEIAIFEGFFDYLTYRNMEKEQSTDYLILNSTSMLFKIENELKKYDKISLFLDNDSNGKSVKTKIENQYKNVEDCSLIYNGFEDLNKWYCERK
>CP033932.1|AZB25275.1|2616703_2616880_-|histone-H1
MKELIEKINAEFEAFTTEANQQVEKGNKAAGTRARKSALELSKLFKDFRKISVEESKK
>CP033932.1|AZB25276.1|2617539_2617938_+|single-stranded-DNA-binding-protein
MSTIIGRVTKNAEISILKNDKQVVNFSVAINDSYKNKQGEKVEQTTYYNCAYWQSPNVAKSLTKGTLVELSGRTSSNAWIGKDGEIRSGLNFHTSNIKFHGGGKREGVQNFVTEKAQDKKTFAEDTDDDLPF
>CP033932.1|AZB25277.1|2617950_2618160_+|addiction-module-toxin-RelE
MEAQFNFQIKQKKDEREWEDIEVYYVTNCDRITAIRYARNISKIFKSEIRLTQGKEPFRTSGTYIYENN
>CP033932.1|AZB25278.1|2618172_2618652_+|hypothetical-protein
MANRCNNKVTFKGNQASLNQVSDLFRTMIDNESKGKIGQLPDFIQSEYGYFSEIYKDETEECSFHYDTRWSPNIEVLWTIANHFDVEFVLSYEESGCMLLGKTFYENEILKDYCLNQSDFQDCSYNEEENNYQFEGNIYEYKDEIMKILLGRKIAFGQS
>CP033932.1|AZB25279.1|2618708_2619140_+|hypothetical-protein
MKKSIKPTEYLLIKAKSEWDDCDFAIIHISEEWKKIQKNRLKVVKIVENDSDLKWLNYEDVNVEFFKFSKENYPQIEEWLSEKNQFFVVLEKDDLKQLLQPEHDLHNHQMQVFRSGNAIYNAFGKHTSEEFFTEQFSLVELIK
>CP033932.1|AZB25280.1|2619173_2619725_+|PRTRC-system-protein-E
MQTNFFRHIAKMDLTGDLQITLRPTTENCFVLSILLNNERCGDEARKLIPPLNLRGTAEELDNGFFEQITTPLQTASGLMVDMEAFMKQLEEVKKKSAMEKEKSDKDKKEKDAKEKKYKEALQKAEELEKEGKYKDAWTALPKASEYPDFAEIIRSKQDEYSKHLAPNLFTEASDENVPIETI
>CP033932.1|AZB25281.1|2619742_2619961_+|PRTRC-system-protein-C
MLLATLLERVFVLKDNGHEIKLTDPEPKWSVEAVMNFYANTYPILTTAKVSAPQIKDDTIQYKFESVMGTKG
>CP033932.1|AZB25282.1|2620038_2621202_+|hypothetical-protein
MNATKKNYIGKNKVARRKTTRKVTSTIGQVRSLASKTKDLERNSERQTEICTNNNASNGFLRCKFLPKQEEVSHFQDSKKILNTERDFYKSLSKFSKQYGVEPMQTKDFGFPYNLALAIWDIETKMKQANADWNQFKLIRTNEKFHFAKEEQFCTNTSLHFIPVVPLFKMLHDKNYKKNAQLLLSVFSYLYHIANVPYYRQQDSYLYWIYEMHEEWMEQEEEEAREDSQNYWREFKMSKNIGDKIEKKLFNLKNLDFFEQRLNCFKIQNEFDIICHKVAFEAFALYSEYPNTTIFRNKPSSEENPYDDDYSNKAISMDMYISFVANTKGCLYNNIEDSINAEFNEYGSIEEPTIYLPINGTEIPKADFDFENRLFTLMEELHQVLTY
>CP033932.1|AZB25283.1|2621211_2621934_+|PRTRC-system-protein-B
MNNVIDTNKYLGMLYEPKSALVFYESLYKNEMYVEHFDMDRNGNPINAHPLTVNEAKTLAKSLVIDKEIEKAFLKSKGILANNILHINPSQKGSVIWYTKAQERQMYFVKNLEIPSGKAKVPAMLWIADKENLSVFALSNDKRPTENTTLHYAPFFNVYNDGDVCMGNVDIKIQNSTSVEEFIEQWESYFFNSYFSHLVGGHNPIDGNLVNLWKKLLKSNEAFPNEILKKNNKTLKNLLR

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Crispr_ID: CP033932_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP033932_5

2691837-2691918

Orphan

Consensus_repeat	Method
TTACTAATGGAATTAGTATATGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP033932_5

>merge|CP033932|5|2691837-2691918|CRISPRCasFinder
TTACTAATGGAATTAGTATATGAGTGGATAGGCTCATATACTTCAAAGTTAAAAAAATCTTTCTAATGGAATTAGTATATGA

>CP033932|5|5|2691837-2691918|CRISPRCasFinder
TTACTAATGGAATTAGTATATGA	GTGGATAGGCTCATATACTTCAAAGTTAAAAAAATC
TTTCTAATGGAATTAGTATATGA

Protein	Signature genes	Signature genes Name	Protein_function
CP033932.1\|AZB25346.1\|2691123_2691819_-\|RNA-polymerase-subunit-sigma	unknown	unknown	unknown
CP033932.1\|AZB25339.1\|2683865_2685128_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|379862
CP033932.1\|AZB25348.1\|2693418_2693928_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375583
CP033932.1\|AZB25345.1\|2690792_2691137_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25343.1\|2689423_2689645_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25338.1\|2680658_2682605_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226220
CP033932.1\|AZB25341.1\|2686360_2686837_+\|cytochrome-C	unknown	unknown	gnl\|CDD\|379587
CP033932.1\|AZB25344.1\|2689999_2690800_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|225412
CP033932.1\|AZB25354.1\|2702142_2702670_-\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25349.1\|2693930_2694815_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|365803
CP033932.1\|AZB25342.1\|2686850_2689121_+\|copper-oxidase	unknown	unknown	gnl\|CDD\|273649
CP033932.1\|AZB27643.1\|2682621_2683869_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
CP033932.1\|AZB27645.1\|2701121_2702150_+\|murein-L,D-transpeptidase	unknown	unknown	gnl\|CDD\|341130
CP033932.1\|AZB25347.1\|2692423_2693410_+\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|143390
CP033932.1\|AZB25340.1\|2685131_2686349_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|379862
CP033932.1\|AZB25353.1\|2700236_2700995_+\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
CP033932.1\|AZB27644.1\|2694859_2695633_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380130
CP033932.1\|AZB25350.1\|2696254_2696659_-\|transposase	unknown	unknown	gnl\|CDD\|376574
CP033932.1\|AZB25352.1\|2699073_2699586_+\|hypothetical-protein	unknown	unknown	unknown
CP033932.1\|AZB25351.1\|2697022_2699071_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379980

Protein	Function_ID	Function_description	E-value
CP033932.1\|AZB25339.1\|2683865_2685128_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	1.36476e-53
CP033932.1\|AZB25348.1\|2693418_2693928_+\|hypothetical-protein	gnl\|CDD\|375583	pfam18138, bacHORMA_1, Bacterial HORMA domain family 1. Family of bacterial HORMA domains found in conserved genome contexts with Pch2/TRIP13 P-loop NTPases. Acts as a 'third component' in broad class of conflict systems reliant on the production of second messenger nucleotide or nucleotide derivatives. Together with Pch2/TRIP13, could act as co-effectors or in regulation of other effectors of the systems.	2.28335e-51
CP033932.1\|AZB25351.1\|2697022_2699071_+\|hypothetical-protein	gnl\|CDD\|379980	pfam17517, IgGFc_binding, IgGFc binding protein. This domain is found at the N terminal of human IgGFc-binding protein and has been shown to confer IgG Fc binding activity. It may play a role in immune protection and inflammation in the intestines of primates.	4.6559e-31
CP033932.1\|AZB25338.1\|2680658_2682605_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
CP033932.1\|AZB25341.1\|2686360_2686837_+\|cytochrome-C	gnl\|CDD\|379587	pfam14376, Haem_bd, Haem-binding domain. This domain contains a potential haem-binding motif, CXXCH. This family is found in association with pfam00034 and pfam03150.	4.83133e-64
CP033932.1\|AZB25344.1\|2689999_2690800_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|225412	COG2856, COG2856, Predicted Zn peptidase [Amino acid transport and metabolism].	2.26808e-21
CP033932.1\|AZB25349.1\|2693930_2694815_+\|AAA-family-ATPase	gnl\|CDD\|365803	pfam00004, AAA, ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.	1.77785e-16
CP033932.1\|AZB25342.1\|2686850_2689121_+\|copper-oxidase	gnl\|CDD\|273649	TIGR01480, unnamed_protein_product, copper-resistance protein, CopA family. This model represents the CopA copper resistance protein family. CopA is related to laccase (benzenediol:oxygen oxidoreductase) and L-ascorbate oxidase, both copper-containing enzymes. Most members have a typical TAT (twin-arginine translocation) signal sequence with an Arg-Arg pair. Twin-arginine translocation is observed for a large number of periplasmic proteins that cross the inner membrane with metal-containing cofactors already bound. The combination of copper-binding sites and TAT translocation motif suggests a mechansism of resistance by packaging and export. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	7.39003e-106
CP033932.1\|AZB27643.1\|2682621_2683869_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	6.83763e-11
CP033932.1\|AZB27645.1\|2701121_2702150_+\|murein-L,D-transpeptidase	gnl\|CDD\|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	6.33415e-13
CP033932.1\|AZB25347.1\|2692423_2693410_+\|nucleotidyltransferase	gnl\|CDD\|143390	cd05400, NT_2-5OAS_ClassI-CCAase, Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme. In vertebrates, 2-5OASs are induced by interferon during the innate immune response to protect against RNA virus infections. In the presence of an RNA activator, 2-5OASs catalyze the oligomerization of ATP into 2-5A. 2-5A activates endoribonuclease L, which leads to degradation of the viral RNA. 2-5OASs are also implicated in cell growth control, differentiation, and apoptosis. This family includes human OAS1, -2, -3, and OASL. CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This class I group includes the archaeal Sulfolobus shibatae and Archeoglobus fulgidus CCA-adding enzymes. It belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this family.	6.05407e-13
CP033932.1\|AZB25340.1\|2685131_2686349_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	8.26515e-73
CP033932.1\|AZB25353.1\|2700236_2700995_+\|LuxR-family-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	2.85842e-18
CP033932.1\|AZB27644.1\|2694859_2695633_+\|hypothetical-protein	gnl\|CDD\|380130	pfam18167, Sa_NUDIX, SMODS-associated NUDIX domain. NUDIX domain with distinctive features in the substrate-interacting region observed associating with SMODS domain synthetases. Predicted to cleave nucleotide diphosphate bonds, potentially to regulate flux through the pore formed by fused 2TM module.	3.00984e-81
CP033932.1\|AZB25350.1\|2696254_2696659_-\|transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	9.07099e-31

>CP033932.1|AZB25346.1|2691123_2691819_-|RNA-polymerase-subunit-sigma
MNVEQKKTDEIVFETLPSDELIDYISFKEEYPEEAAAAFTEFCSRFERDILQKAEIYCNKFNYSEVVALEIATCAFARVWKYHSFNKSKAKYPDDIDRSILLWLYPIVYTQLVKYGDLNTCAEPDEDDLSIVENIDDLISLTVGDDDIQKKRELKIRLEIIERAMLGLSEKHKIVYLTYKAYENTGKKNIPRSVGKKLRDRLNLVQNSIQVYKKEANDHINNYLKAFNGNR
>CP033932.1|AZB25345.1|2690792_2691137_-|hypothetical-protein
MGIDKKYIGKVTETNLDDWLHSTGFLFPQNKTQIERFNKLYEDYDFKLKNTGINVKSIIDGSFCVEKESKIISIDTNLSHEIESLKMVARKGQSNISQSVFDKMKQNQKKKKGD
>CP033932.1|AZB25344.1|2689999_2690800_-|ImmA/IrrE-family-metallo-endopeptidase
MIDSSSLSKIKKLAGSISGNFNTEKIIPLHLIAESEDIEVFYDHYDKGTFDGMTVYDDNEFYIHINIDNHNRFNSPRSRFTLAHELGHYFIDTHRVGLKLGILEPHPSKIDRVQFDKIEREADYFAACLLMPEESFQRNLWKRKKFSFKVIDELSKEYNVSKTSCALRFAEIGNHPIKIVYAENGFVKWQKNSQGFPFWNLLNDKKVPEGLAMADYFKNVKTSIENPEEIFAIDCFENVKSEDSRRIFYEHCIVYENCALSIIWED
>CP033932.1|AZB25343.1|2689423_2689645_-|hypothetical-protein
MSEMSDFKKNYFKHLEEEVTAILKENQNIVSVFINFAQSKNINLIEQELKYAQMSGITVNSKDLFLKLNEDIL
>CP033932.1|AZB25342.1|2686850_2689121_+|copper-oxidase
MNRYKKIPIRILQTVLILLCTQTLFAQKVVHYDLYVKDTLVNYAGKQKRAIAVNGQIPMPTLTFTEGDTAEIVVHNQLKESTSLHWHGVFLPNKEDGVPWLTQKPIAPGTTYTYRFPIIQHGTHWYHSHSGLQEQIGMYGSFVMKKRDNDRTFRKGIDDLPTVPIILSEWTNLNPDNINRMLHNANDWAAIKKNATQSYAEAIKEGYFKTKIKNEWKRMLAMDVSDVYYDKILINGNHTTDLKSVDGKTLKAGDKVRLRVSNGGASSYFWLRYAGGKITVVANDGNDVEPVEVDRLIIAVSETYDIVVTIPEDGVSYEFLATTEDRTQSASYFVGNGIKQLISPLPKLKYFEGMKMMNDMMKMNGDLDDMGMKMSLNQMDMNVVMYPEITGDAKQKQDHSQHNMNMDNDPNRYNANALGDIKTLNYAMLQSPYNTTLPKDAPVKELKFTLTGNMNRYVWSMDNKILSETDKIPVKKGEILRITIYNNSMMRHPMHLHGFDFRVINGKGEKSPLKNVLDIMPMETDTIEFLANEEGDWFFHCHILYHMMSGMNRVFAVDDYQNPYLPNKKQAYNKLQRESNMSHFMAQNDFATNGNDGDAMFQNARWSLGTEWRLGYNDMHGYEVETHLGRYIGKMQWFMPFIGFDWRYRKMGIDEHETNLFGQRNEKDTRRAISLGFMYTLPMLVNFQAEVYHDGIVRLSLMREDIPITKRLRAGFMVNTDMEYMTELRYIINKNVGIRTHYDSDMGFGVGLSLNY
>CP033932.1|AZB25341.1|2686360_2686837_+|cytochrome-C
MNNKLRKLKPFNIAVGILIIISICIQFIQPLRNQSDVVPATHIERVYTVPQNVKTILAQSCYDCHSNNTRYPWYSRIQPGAWYMAEHIKKGKEELNFSEFGEYSARRQRNKFRAMAGQVKDGEMPLSSYTLIHRNAVLSPEDKQVLMAWFGTMEDSIK
>CP033932.1|AZB25340.1|2685131_2686349_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKYYLVITIALLMSVLLSCKDNKHDHAGNNDGSYYTCSMHPQVVSDKPGHCPICHMELVRVEKSKQADPNTIQLNSEQIKLGNIKTDTLKDGLLGDRVILTGVLNFNQYNMQSVSSRVMGRVEKLHYKNVGDFVTKGSPLMEIYSEELNNAKQEYLLALEKKKTFGNINSIDFDQLIQSSKNKLLLWGMTDNQVRALQSAGKISATTTFYSTASGYITSLQVVEGGYVAEGGTIVDLADLSTIWAEAQAYSSQMSLINQTKTATVQIPDLNNKVITGKIDFSNPELNPSSRINLIRITVPNPNKDLKPGMPVYVFLETPKTKGITMPVDAVIRNGKSETVWVQTGEKTFKSRMVKTGTEIDNRIEIVSGLVDGDIVVVSGAYLLNSEYIFRNGADPMAGHDMSSM
>CP033932.1|AZB25339.1|2683865_2685128_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKYIICFLMIILVLYSCNNNTDKTSHPDNSHTAKNSPTYTCPMHPEVTSNKPGKCPKCGMELVQKTVNTNETESIELNTLLKPTNEFVISDIPTIRMQSEHKDITVQALGNIAYDTRQTGNISARISGRIEKLYIRYKFQKIAKGQKVMDIYSPELMEAQVNLLFLLKNDATNNMMINAAKQKLLLLGMSENQLQSIIQKGKPDLSVSVYSNYAGHIHETGTAGSMGSSTSPSNSMGEISETSSELSLKEGMYVQKGQTIFNVFNPGKSWVLLNIFPEDVPLVKTGQTVSIIPEVAPEKKFIGTIGFIEPFFRPGSKTLSVRVYFDNNRMQLPIGSQVKSEISTAGISGNWIPKEAVISLGLTKVILKKVDRGFIVNKIETGNEANGYIEVLQGLLPVEEIAGNAQYLMDSESFVRTKNN
>CP033932.1|AZB27643.1|2682621_2683869_+|TolC-family-protein
MKKIIFTAFIVCLFTNINAQVISLQNVIDSIQTNHPIVKMYDNEIRSMDEAAKGARSWMPPTIGVGQFMTPYNVNLWKRDGEMKGMGSAMLSIEQMIPNKKKLDAEEAYMNAMSSVEKENKGAGINEIIQDAKLLYSEWIVLLKRLDVVAENEKMLNFMIKNAEIRYKNGVGKIGAYYKAKAALGSTHNMQIMYENDIKEKRIRLNTLMGRNPMAPFEIDTIFSFNDYSDMVFDTALFNKNRSDLKSLDQQIRLTTLKQETERQSLKPEFGVRFENMYGFGGQPMQYTAMAMVKLPFVNWASKMSKANIASLKWKADALSSQKNMMINEYSGMAYGMRNEFDLKKNQLSLYRDDIIPALKNNFKTMQLGYEQNTEELFMLYDAWEKLNMTQLEYLDILSKAFEMQITIDRLIERK
>CP033932.1|AZB25338.1|2680658_2682605_+|efflux-RND-transporter-permease-subunit
MKIKWFKKKANKNVGYEKIPEEVRLSIIEKSCKQVSRGVFFSTIIIITSFLPVFLLTGQEGKLFHPLAYTKTFILVVDALLVLTLAPVLISFFMKGKFKSEHSNPINRGLEKLYEPVIKWCVKWRKTVLGINIAALIISIPMILNLGREFMPPLDEGSLLFMPVTLPDVSNSEAKRILQVQDKIIKSVPEVAHVLGKAGRANTATDNSPISMIETIILLKPQNEWRDGIKKNDIINELNAKLQMPGVTNGWTMPIINRINMLSTGIRTDVGIKVYGQNLDSIYSLSQKIKTELDGVAGIKDMYVEPITGGKYVDIVINRDEIARYNISIDDVNNLVESALGGMKLTTTIEGRQRFSVNARYGQDFRNNIEALKRLPVQTMDFGSIPLGSVAEVKLSEGAPMINSENAMLRGTVLFNVRERDLGSTVEEAKAKLNNMMLKMPQGYFLEWSGQYENLIRGEQTLKWIMPIVLVIIFLSMYFAFHSMREAFFNLISIPFALIGGVFMISLWGVNLSVAVAVGFIALFGLAVETGIVMVIYLNDAMQQLVLLKGNSRETITNEDLREYVIHGAAKRLRPKIMTVCVTLFGLVPILWSTGVGSDMMKPIVLPMVGGVFTSAIHILLVTPIIFLMQKEYELKKFGKIDVLDAAH
>CP033932.1|AZB25347.1|2692423_2693410_+|nucleotidyltransferase
MKLSDKDLQFFISKIKLQPENMGKYRDQVNNLKEKLDKKIAEDDRHGLKVEKYLLAGSWKKHTILKPTGDHPIDIDLVLFVTGDEDIHNDIGKLFDFIVEYLEEIYPQKDISKDVDAAGNTKSVTIYFSGSGLSVDIVPVVPLSTPKDYVWQPSRHGNGKKYITSISKQLSFSLNRRQENSAYTSIVRAIKWWRNYKELKPSDNEPGLSSFTIELIVAYLDINKGIQTNIEEGIIRFFEFVSSTEFPEIIFQDSIRSVPTQYDSAIYVADNTNKENNVAKRMTKPRWAEIIEEAEEAFDTLNFAQARNNEGDTIQEWKSVFGPTFNIK
>CP033932.1|AZB25348.1|2693418_2693928_+|hypothetical-protein
MYGTNTKTNTYTVLDIRKTFESCEADIRTIARRTNKWTMEYVDKVFHDVLKYAEKYYLQSVSITLINTNTGLPVKAAKFIVNDLGDATDSERAGKNNDWPDTDNTSLSIILSHTQKWRNLTSEEKTNFQKELKLSWGSTDINTNFPHLQQSDAQLYASNGYELQKKNFK
>CP033932.1|AZB25349.1|2693930_2694815_+|AAA-family-ATPase
MSTIFDNITELPSREIAERAKHLIGFENKYNRILSNLKLLLDQEGLVEWSKKFHKTELPVISQLKEKYPLIILAGDAGTGKTVSAEAIADRMLRELKKEGFFLKLSTRVRGEGLHGQMGNLVNDAFAELKTQAGKKRIAFLLIDEADAIASTRSTMQMHQEEKAAVNTLIQKIDEIRELNGRAILFMSTNRLHFLDEAIVRRAAIILEFERPTFEERVLLFKTSLAGVEITDKQLEELANLSGEESNNGLSFSFSDIRLRILPEAVAKCFPDKALDFETVAETIKKLNPSPKIV
>CP033932.1|AZB27644.1|2694859_2695633_+|hypothetical-protein
MVGGYIEKGNWTESKYSTTGYITLLTFIVTFVYENYNRLGFYFQSKVLLKNTDVRVSISYLYRIKVENEYLLVKSRTRKYFQPVGGCYKTLPGCERKFEELDVRPDRKFETEKGIAKNDLRVHVKGKNLIEFLKWFDSKEDREISPWREFCEELIATEILTWRPFRYIDYRFKKKIQSPIIDLDMGGKGLFIYEVFDLVINDEQMPLLKDLKNKTSENYIWVTDEVIQTLGHETGSKSFPHEIGPHTKYAQNLKWSK
>CP033932.1|AZB25350.1|2696254_2696659_-|transposase
MARSRYLLYKSREKWTLSQKQRASILFTQYPDLEQAYGLTDGLRKIYNQNISKSVAMTKLAHWFRNVEEADFKSFSTLRKTIMNRYRNILNYFDQRSTNAAAESFNAKIKNFRMQLRGVKDRTFFIFRLAKLFA
>CP033932.1|AZB25351.1|2697022_2699071_+|hypothetical-protein
MNKFYFLIVFFITQFFYCQLDNTHYLQPIVFGAYGSTAATISEEYIYLSTPSASNISVTIRMADGTTIPRLSVYNINAATSSIVTNGVVTFSNTSPLRLSVINASNVVLAPGTSPMTVATTRAGTIIPANVGGMIFQSTSDFFVNYRGADPSQAGSSLTKGKVALGKNFFWGGTPNEFTTQVPEVGNMVSIMATEDNTIITINNIDSGTEFINGANATPLTGTTFTRTLQKGQSFILYAKVKINTFSLQDKGWLGAKISSDKNIAVTVGGLMQQGSVDTGTVSDSRDFAVDQLVPVDQLGNEYIVMQGNGGVYERVIVIATESNTTITMNANTNPSYTLANVGDYAIVPATFFTNKNMYIKTNKAVYVFHKIFGSSSLATNSFMFIPPISCFGQTSVNMIPDAKQIGSTVYPNTELAVLAASGAANAPVVTVSGSAAIAPIVAGGTAVPGNPNWRSYRYDIANAAGGTATVKNLRVSSAATIQAELIGASGNAGFGGYYSGFGTSPIVNISVSNSPTIRPCTGNTGNSSLSVSSGLGSYQWYKNNTLIAGATTNSYAIPAGDTTSADYNVIITVPGGCVLYSNVVRSYACPCYKPGATGTPEITKIGISTRASKSTANWPADINNGFIALESNDKGVVITRVSDPETSITNPIDGMIVFDTDDICLKIYDGTKWGCINQTCN
>CP033932.1|AZB25352.1|2699073_2699586_+|hypothetical-protein
MKAIILFLLIILSSPIKAQIGFEKTIIDGSGLIDFPIGTTKGIILPQVADNTSMTDVSEGTFIFDGTTSRVKYYNGITWIELTGQTGTSRTLLPGAENNQSKGIIIGASDSDAKGVLILESQDKALILPKVIDPATNVKSPSPGMMCYDPVLKLVCFYNGTSWAFWGNID
>CP033932.1|AZB25353.1|2700236_2700995_+|LuxR-family-transcriptional-regulator
MEQIKRFFNEKNEVSKDADIDFSQDGEYLEAVKALARTTYQSLYVINYQTKGFEYVSENPLFLCGKTSAEVKNLGYAFYFQNVKPEDVEMLIKINEAGFKFYDKIPVEDRKLYYISYDFYLINGQKNMILVNHKLTPMFLTEDGQVWKALCAVSLSNNTSSGNVVLSKEGSDEIWRYDLTADKWEKDERVKLSSREHEILSLYASGLTISEIAEKLFITADTVKFHRKKLFEKIEVSNIAEALSYAKTNKLL
>CP033932.1|AZB27645.1|2701121_2702150_+|murein-L,D-transpeptidase
MKKTFLYACLCAVLLTSCKKEIEKISDTFKDTVSASEIPETEKDTVKKDSVPVVKKESVPPMMQENGFYNAFVIPKDKKLRDSVYAEFSKKYNEQERTAILALNRLDSKSKWNADTLVVPAKIDTTLMAYSPFPMQLDVLSGVKKFVIFSYPIQAYAVYSNGSLVKWGPTSMGKKSAQTTRGLTFANWKKKLSISTVSSEWKLPYNFNIHNIGGIGWHEYTLPGYPASHSCLRLLRKDAQWLYSYADTWILNPGGATTKARGTAVMVFGDYNWGGRKPWKKLLDDPNANNISVEELTKLLEPDVPKMLKEQANREKVADSIKTAKAMAAPIQNERATDTLSK
>CP033932.1|AZB25354.1|2702142_2702670_-|hypothetical-protein
MTTEETTLDRIRTRPRFKMFTHLTKEEYAQNLKKYLAEHKKEFSGNINKEVATIWVETEYDNYWKPRLALRVEIEDEETVIRGVFGPSSAVWTFFMFLYFSFSILWMTFFTMYYVEKQIKSAEYPWALSASFVMLFFILLTYVAARFGQHKGKDEMLKLRQFAEESTLQFEKKII

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065458	Streptococcus phage IPP17, complete genome	12566-12594	6	0.793
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065495	Streptococcus phage IPP58, complete genome	11963-11991	6	0.793
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065470	Streptococcus phage IPP29, complete genome	14220-14248	6	0.793
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065494	Streptococcus phage IPP57, complete genome	11963-11991	6	0.793
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	MG592499	Vibrio phage 1.124.O._10N.286.49.B1, partial genome	31536-31564	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	MG592531	Vibrio phage 1.164.O._10N.261.51.A7, partial genome	32360-32388	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	MG592611	Vibrio phage 1.246.O._10N.261.54.E10, partial genome	29199-29227	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065462	Streptococcus phage IPP21, complete genome	14891-14919	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065454	Streptococcus phage IPP12, complete genome	13770-13798	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065471	Streptococcus phage IPP30, complete genome	15222-15250	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065461	Streptococcus phage IPP20, complete genome	14812-14840	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065463	Streptococcus phage IPP22, complete genome	13700-13728	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065453	Streptococcus phage IPP11, complete genome	14265-14293	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065469	Streptococcus phage IPP28, complete genome	13017-13045	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065460	Streptococcus phage IPP19, complete genome	11736-11764	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065499	Streptococcus phage IPP63, complete genome	12638-12666	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KT337342	Streptococcus phage phiARI0131-2, complete genome	21360-21388	7	0.759
CP033932_1	1.1\|1205509\|29\|CP033932\|CRISPRCasFinder	1205509-1205537	29	KY065459	Streptococcus phage IPP18, complete genome	14258-14286	7	0.759

1. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065458 (Streptococcus phage IPP17, complete genome) position: , mismatch: 6, identity: 0.793

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caatcaaggattgtattggcagaaaaaaa	Protospacer
.  * ** **** ****************

2. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065495 (Streptococcus phage IPP58, complete genome) position: , mismatch: 6, identity: 0.793

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caatcaaggattgtattggcagaaaaaaa	Protospacer
.  * ** **** ****************

3. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065470 (Streptococcus phage IPP29, complete genome) position: , mismatch: 6, identity: 0.793

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caatcaaggattgtattggcagaaaaaaa	Protospacer
.  * ** **** ****************

4. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065494 (Streptococcus phage IPP57, complete genome) position: , mismatch: 6, identity: 0.793

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caatcaaggattgtattggcagaaaaaaa	Protospacer
.  * ** **** ****************

5. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to MG592499 (Vibrio phage 1.124.O._10N.286.49.B1, partial genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
cgaataatgattttattgtcagaaaaata	Protospacer
.    ************* ******** *

6. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to MG592531 (Vibrio phage 1.164.O._10N.261.51.A7, partial genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
cgaataatgattttattgtcagaaaaata	Protospacer
.    ************* ******** *

7. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to MG592611 (Vibrio phage 1.246.O._10N.261.54.E10, partial genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
cgaataatgattttattgtcagaaaaata	Protospacer
.    ************* ******** *

8. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065462 (Streptococcus phage IPP21, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

9. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065454 (Streptococcus phage IPP12, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

10. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065471 (Streptococcus phage IPP30, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

11. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065461 (Streptococcus phage IPP20, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

12. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065463 (Streptococcus phage IPP22, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

13. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065453 (Streptococcus phage IPP11, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

14. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065469 (Streptococcus phage IPP28, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

15. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065460 (Streptococcus phage IPP19, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

16. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065499 (Streptococcus phage IPP63, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

17. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KT337342 (Streptococcus phage phiARI0131-2, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

18. spacer 1.1|1205509|29|CP033932|CRISPRCasFinder matches to KY065459 (Streptococcus phage IPP18, complete genome) position: , mismatch: 7, identity: 0.759

tcttaaatgattttattggcagaaaaaaa	CRISPR spacer
caaccaaggattgtattggcagaaaaaaa	Protospacer
.  . ** **** ****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

539014 : 566538

Riemerella_phage(57.14%)

transposase,integrase,holin,bacteriocin

attL 538228:538243|attR 568378:568393

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
538228:538243	attL	NA	NA	NA	NA
AZB23572.1\|539014_539368_+\|transposase	transposase	NA	NA	NA	NA
AZB23573.1\|539387_540326_+\|transposase	DDE transposase	NA	NA	NA	NA
AZB23574.1\|541363_541654_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
AZB23575.1\|541650_542538_-\|integrase	integrase	A0A0K2CP59	Brevibacillus_phage	1.4e-24	29.8
AZB23576.1\|542618_542816_-	30S ribosomal protein S21	NA	NA	NA	NA
AZB23577.1\|543614_544784_+\|integrase	site-specific integrase	NA	NA	NA	NA
AZB23578.1\|545198_545417_-	hypothetical protein	NA	NA	NA	NA
AZB23579.1\|545672_546305_+	DUF4760 domain-containing protein	NA	NA	NA	NA
AZB23580.1\|546498_547050_-	N-acetylmuramidase family protein	A0A142IF03	Pseudomonas_phage	5.5e-43	50.0
AZB23581.1\|547046_547595_-	hypothetical protein	NA	NA	NA	NA
AZB23582.1\|547560_548073_-\|holin	holin	NA	NA	NA	NA
AZB23583.1\|548092_550873_-	hypothetical protein	F5A399	Riemerella_phage	5.2e-129	36.4
AZB23584.1\|550897_551890_+	acyltransferase	A9YX16	Burkholderia_phage	7.0e-20	28.0
AZB23585.1\|551896_553669_-	hypothetical protein	NA	NA	NA	NA
AZB23586.1\|553672_554695_-	hypothetical protein	F5A3A0	Riemerella_phage	4.5e-38	33.8
AZB23587.1\|554691_555183_-	hypothetical protein	NA	NA	NA	NA
AZB23588.1\|555182_560189_-	hypothetical protein	F5A3A4	Riemerella_phage	1.9e-129	28.7
AZB23589.1\|560185_560395_-	hypothetical protein	NA	NA	NA	NA
AZB23590.1\|560403_560928_-	hypothetical protein	NA	NA	NA	NA
AZB23591.1\|560991_561498_-	hypothetical protein	NA	NA	NA	NA
AZB23592.1\|561508_561907_-	hypothetical protein	NA	NA	NA	NA
AZB23593.1\|561903_562380_-	hypothetical protein	F5A3B3	Riemerella_phage	5.1e-21	44.1
AZB23594.1\|562370_562691_-	hypothetical protein	NA	NA	NA	NA
AZB23595.1\|562687_563017_-	hypothetical protein	NA	NA	NA	NA
AZB23596.1\|563020_564127_-	hypothetical protein	NA	NA	NA	NA
AZB23597.1\|564144_564516_-	hypothetical protein	NA	NA	NA	NA
AZB23598.1\|564542_565172_-	hypothetical protein	NA	NA	NA	NA
AZB23599.1\|565321_565717_+	hypothetical protein	NA	NA	NA	NA
AZB23600.1\|565727_566012_+	hypothetical protein	NA	NA	NA	NA
AZB23601.1\|566114_566333_+	hypothetical protein	NA	NA	NA	NA
AZB23602.1\|566319_566538_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
568378:568393	attR	NA	NA	NA	NA

DBSCAN-SWA_2

572159 : 586637

Riemerella_phage(18.18%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZB23620.1\|572159_573212_-	hypothetical protein	F5A3C5	Riemerella_phage	4.6e-54	36.4
AZB23621.1\|573436_573754_+	hypothetical protein	NA	NA	NA	NA
AZB23622.1\|573763_574294_+	hypothetical protein	NA	NA	NA	NA
AZB23623.1\|574364_574631_+	XRE family transcriptional regulator	NA	NA	NA	NA
AZB23624.1\|574659_574872_-	hypothetical protein	NA	NA	NA	NA
AZB23625.1\|574874_576287_-\|portal	phage portal protein	F5A3C6	Riemerella_phage	2.8e-54	35.0
AZB27524.1\|576302_577829_-	hypothetical protein	A0A0A8WEW2	Clostridium_phage	3.1e-27	26.1
AZB23626.1\|577859_578039_-	hypothetical protein	NA	NA	NA	NA
AZB23627.1\|578041_578401_-	hypothetical protein	A0A088C3B4	Flavobacterium_sp._phage	2.0e-17	40.6
AZB27525.1\|578381_578828_-	DNA-packaging protein	G8EYI7	Enterobacteria_phage	6.3e-29	48.4
AZB23628.1\|579063_579468_-	hypothetical protein	A0A0X8WNX5	Ralstonia_phage	4.0e-06	29.7
AZB23629.1\|579485_579725_-	hypothetical protein	I6R1G5	Croceibacter_phage	3.0e-14	51.4
AZB23630.1\|579726_580074_-	hypothetical protein	NA	NA	NA	NA
AZB23631.1\|580909_581257_-	hypothetical protein	NA	NA	NA	NA
AZB23632.1\|581306_581591_-	hypothetical protein	NA	NA	NA	NA
AZB23633.1\|581587_582004_-	hypothetical protein	NA	NA	NA	NA
AZB23634.1\|581996_582653_-	HNH endonuclease	A0A1S5SAF6	Streptococcus_phage	9.0e-08	32.1
AZB23635.1\|582649_583096_-	RusA family crossover junction endodeoxyribonuclease	S0A1C6	Cellulophaga_phage	1.5e-27	44.5
AZB23636.1\|583155_583575_-	hypothetical protein	NA	NA	NA	NA
AZB23637.1\|584658_585414_-	DUF4373 domain-containing protein	F0PII1	Enterococcus_phage	1.8e-31	54.5
AZB23638.1\|585422_586637_-	DEAD/DEAH box helicase	A0A173H0P6	Pseudoalteromonas_phage	2.7e-42	31.3

DBSCAN-SWA_3

993805 : 1033749

Klebsiella_phage(50.0%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZB23970.1\|993805_994531_+\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	NA	NA	NA	NA
AZB23971.1\|994530_994902_+	ribonuclease P protein component	NA	NA	NA	NA
AZB23972.1\|995169_995775_+	DUF4126 domain-containing protein	NA	NA	NA	NA
AZB23973.1\|995820_997965_-	hypothetical protein	NA	NA	NA	NA
AZB27544.1\|997966_998518_-	hypothetical protein	NA	NA	NA	NA
AZB23974.1\|998507_999215_-	hypothetical protein	NA	NA	NA	NA
AZB23975.1\|999230_1000520_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AZB23976.1\|1000556_1001354_-	hypothetical protein	NA	NA	NA	NA
AZB23977.1\|1001543_1001840_-	hypothetical protein	NA	NA	NA	NA
AZB27545.1\|1001849_1003286_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
AZB23978.1\|1003455_1003869_-	hypothetical protein	NA	NA	NA	NA
AZB23979.1\|1003899_1004379_-	hypothetical protein	NA	NA	NA	NA
AZB23980.1\|1004513_1006247_-	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
AZB23981.1\|1006494_1007700_-	diaminopimelate decarboxylase	NA	NA	NA	NA
AZB23982.1\|1007957_1009181_-	3'-5' exonuclease	NA	NA	NA	NA
AZB23983.1\|1009319_1010846_-	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	3.5e-71	38.5
AZB23984.1\|1011196_1012606_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
AZB23985.1\|1012610_1012988_+	hypothetical protein	NA	NA	NA	NA
AZB23986.1\|1013006_1013306_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	6.1e-12	45.7
AZB23987.1\|1013346_1014099_-	nitrilase family protein	NA	NA	NA	NA
AZB23988.1\|1014287_1014728_+	hypothetical protein	NA	NA	NA	NA
AZB23989.1\|1014834_1016316_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
AZB23990.1\|1016653_1017592_-\|transposase	DDE transposase	NA	NA	NA	NA
AZB23991.1\|1017611_1017965_-\|transposase	transposase	NA	NA	NA	NA
AZB23992.1\|1017958_1018912_-\|transposase	DDE transposase	NA	NA	NA	NA
AZB23993.1\|1018931_1019285_-\|transposase	transposase	NA	NA	NA	NA
AZB23994.1\|1027184_1029755_+	carboxypeptidase-like regulatory domain-containing protein	NA	NA	NA	NA
AZB23995.1\|1029903_1031121_-	T9SS C-terminal target domain-containing protein	NA	NA	NA	NA
AZB23996.1\|1031830_1032088_-	50S ribosomal protein L27	NA	NA	NA	NA
AZB23997.1\|1032100_1032679_-	50S ribosomal protein L21	NA	NA	NA	NA
AZB23998.1\|1032861_1033749_+\|protease	metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_4

3460602 : 3520377

uncultured_Caudovirales_phage(33.33%)

transposase,integrase

attL 3462060:3462076|attR 3498631:3498647

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZB25973.1\|3460602_3460956_+\|transposase	transposase	NA	NA	NA	NA
AZB25974.1\|3460975_3461914_+\|transposase	DDE transposase	NA	NA	NA	NA
AZB25975.1\|3461910_3462150_-	hypothetical protein	NA	NA	NA	NA
3462060:3462076	attL	NA	NA	NA	NA
AZB25976.1\|3463329_3464322_+\|integrase	integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.5e-38	31.7
AZB25977.1\|3464324_3464951_+	restriction endonuclease subunit M	NA	NA	NA	NA
AZB25978.1\|3465374_3466040_-	restriction endonuclease subunit S	NA	NA	NA	NA
AZB25979.1\|3466032_3467649_-	SAM-dependent DNA methyltransferase	A0A2H4PQP4	Staphylococcus_phage	3.4e-32	25.9
AZB25980.1\|3467652_3470721_-	type I restriction endonuclease subunit R	NA	NA	NA	NA
AZB25981.1\|3471214_3471475_-	DNA-binding protein	NA	NA	NA	NA
AZB25982.1\|3471566_3471827_-	hypothetical protein	NA	NA	NA	NA
AZB25983.1\|3472113_3472635_-	hypothetical protein	NA	NA	NA	NA
AZB25984.1\|3472655_3473009_-	VOC family protein	NA	NA	NA	NA
AZB25985.1\|3473060_3473600_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AZB25986.1\|3473778_3475449_-	AraC family transcriptional regulator	NA	NA	NA	NA
AZB25987.1\|3476556_3476886_+	hypothetical protein	NA	NA	NA	NA
AZB25988.1\|3476943_3478287_-	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
AZB25989.1\|3478296_3481497_-	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
AZB25990.1\|3481517_3482804_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
AZB25991.1\|3483427_3483649_+	hypothetical protein	NA	NA	NA	NA
AZB25992.1\|3484261_3484585_+	hypothetical protein	NA	NA	NA	NA
AZB25993.1\|3485048_3486110_+	hypothetical protein	NA	NA	NA	NA
AZB25994.1\|3486184_3487897_+	hypothetical protein	NA	NA	NA	NA
AZB25995.1\|3487938_3489675_+	hypothetical protein	NA	NA	NA	NA
AZB25996.1\|3489727_3490372_+	hypothetical protein	NA	NA	NA	NA
AZB25997.1\|3490485_3491280_+	hypothetical protein	NA	NA	NA	NA
AZB25998.1\|3492137_3493994_+	hypothetical protein	NA	NA	NA	NA
AZB25999.1\|3493997_3494888_+	hypothetical protein	NA	NA	NA	NA
AZB26000.1\|3494884_3496216_+	hypothetical protein	NA	NA	NA	NA
AZB26001.1\|3496222_3496948_+	TatD family deoxyribonuclease	NA	NA	NA	NA
AZB26002.1\|3497168_3498377_-\|integrase	site-specific integrase	H7BUI8	unidentified_phage	2.5e-40	35.2
AZB26003.1\|3499354_3500401_+	hypothetical protein	NA	NA	NA	NA
3498631:3498647	attR	NA	NA	NA	NA
AZB26004.1\|3500513_3501011_+	DUF4280 domain-containing protein	NA	NA	NA	NA
AZB26005.1\|3500988_3503853_+	hypothetical protein	NA	NA	NA	NA
AZB26006.1\|3503876_3504893_+	hypothetical protein	NA	NA	NA	NA
AZB26007.1\|3504905_3505184_+	hypothetical protein	NA	NA	NA	NA
AZB26008.1\|3505356_3506577_-	MFS transporter	NA	NA	NA	NA
AZB26009.1\|3506672_3507548_-	AraC family transcriptional regulator	NA	NA	NA	NA
AZB26010.1\|3507723_3508047_+	hypothetical protein	NA	NA	NA	NA
AZB26011.1\|3508292_3509036_+	NAD(+)--rifampin ADP-ribosyltransferase	NA	NA	NA	NA
AZB26012.1\|3509104_3510049_-	3',5'-cyclic-nucleotide phosphodiesterase	NA	NA	NA	NA
AZB26013.1\|3510277_3510820_+	hypothetical protein	NA	NA	NA	NA
AZB26014.1\|3510904_3511153_+	hypothetical protein	NA	NA	NA	NA
AZB26015.1\|3511447_3512902_+	hypothetical protein	NA	NA	NA	NA
AZB26016.1\|3513586_3513814_+	hypothetical protein	NA	NA	NA	NA
AZB26017.1\|3513941_3514130_+	hypothetical protein	NA	NA	NA	NA
AZB26018.1\|3514203_3515532_+	hypothetical protein	NA	NA	NA	NA
AZB27691.1\|3515641_3516088_+\|transposase	transposase	NA	NA	NA	NA
AZB26019.1\|3516132_3516465_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZB26020.1\|3516647_3517844_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZB26021.1\|3518542_3519772_+	hypothetical protein	NA	NA	NA	NA
AZB26022.1\|3519774_3519969_-	hypothetical protein	NA	NA	NA	NA
AZB26023.1\|3519948_3520377_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

3742748 : 3792941

uncultured_Mediterranean_phage(14.29%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZB26199.1\|3742748_3743093_+\|transposase	transposase	NA	NA	NA	NA
AZB26200.1\|3743122_3744061_+\|transposase	DDE transposase	NA	NA	NA	NA
AZB26201.1\|3744657_3745416_-	alpha/beta hydrolase	NA	NA	NA	NA
AZB27705.1\|3745748_3746384_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
AZB27706.1\|3746438_3749231_-	excinuclease ABC subunit A	A0A1B1IVR3	uncultured_Mediterranean_phage	1.5e-216	44.6
AZB26202.1\|3749865_3751677_+	TonB-dependent receptor	NA	NA	NA	NA
AZB26203.1\|3751748_3752465_+	DUF2490 domain-containing protein	NA	NA	NA	NA
AZB26204.1\|3752461_3754513_-\|protease	Zn-dependent protease with chaperone function	NA	NA	NA	NA
AZB26205.1\|3754521_3754968_-	phosphohydrolase	A0A0F6WCW4	Sinorhizobium_phage	1.0e-18	42.9
AZB26206.1\|3755049_3755385_-	DUF1508 domain-containing protein	NA	NA	NA	NA
AZB26207.1\|3755531_3757307_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
AZB26208.1\|3757359_3757716_-	four helix bundle protein	NA	NA	NA	NA
AZB26209.1\|3757765_3758944_-	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
AZB26210.1\|3759049_3759514_-\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	1.1e-07	29.5
AZB26211.1\|3759595_3761989_-	3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
AZB27707.1\|3762042_3762495_-	MarR family transcriptional regulator	NA	NA	NA	NA
AZB26212.1\|3762660_3763584_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	3.6e-10	29.5
AZB26213.1\|3763684_3764062_-	GxxExxY protein	A0A0P0YNF4	Yellowstone_lake_phycodnavirus	1.2e-09	33.7
AZB26214.1\|3764970_3765945_-	iron ABC transporter permease	NA	NA	NA	NA
AZB26215.1\|3765960_3766524_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
AZB26216.1\|3766556_3767681_+	ferredoxin--NADP reductase	NA	NA	NA	NA
AZB26217.1\|3767737_3768295_+	SanA protein	NA	NA	NA	NA
AZB26218.1\|3768291_3770901_-	outer membrane protein assembly factor	NA	NA	NA	NA
AZB26219.1\|3770886_3771612_+	RNA methyltransferase	NA	NA	NA	NA
AZB26220.1\|3771682_3772180_-	phosphoribosyl-ATP pyrophosphatase	NA	NA	NA	NA
AZB26221.1\|3772172_3772493_-	hypothetical protein	NA	NA	NA	NA
AZB26222.1\|3772572_3772923_-	YtxH domain-containing protein	NA	NA	NA	NA
AZB26223.1\|3773018_3773693_-	(d)CMP kinase	NA	NA	NA	NA
AZB26224.1\|3773766_3774759_-	penicillin-binding protein	NA	NA	NA	NA
AZB26225.1\|3774925_3775633_+	UMP kinase	NA	NA	NA	NA
AZB26226.1\|3776382_3776937_+	ribosome recycling factor	NA	NA	NA	NA
AZB27708.1\|3777113_3778175_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
AZB26227.1\|3778223_3779021_-	hypothetical protein	NA	NA	NA	NA
AZB26228.1\|3779309_3780767_-	YjgP/YjgQ family permease	NA	NA	NA	NA
AZB26229.1\|3780874_3781522_-	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
AZB27709.1\|3781664_3782126_-	hypothetical protein	NA	NA	NA	NA
AZB26230.1\|3782217_3784830_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.4e-64	40.9
AZB26231.1\|3785198_3786332_+	hypothetical protein	NA	NA	NA	NA
AZB26232.1\|3786548_3789824_+	cytochrome C biogenesis protein CcsB	NA	NA	NA	NA
AZB26233.1\|3790388_3791255_+	SPFH domain-containing protein	NA	NA	NA	NA
AZB26234.1\|3791333_3791522_+	Arc family DNA binding domain-containing protein	NA	NA	NA	NA
AZB26235.1\|3791583_3792426_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.2e-81	54.2
AZB26236.1\|3792413_3792941_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

4272842 : 4295882

Bacillus_phage(66.67%)

transposase,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZB26650.1\|4272842_4273544_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AZB27738.1\|4273548_4274307_+	peroxide stress protein YaaA	NA	NA	NA	NA
AZB26651.1\|4274307_4275156_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
AZB26652.1\|4275199_4275559_+	DUF4180 domain-containing protein	NA	NA	NA	NA
AZB26653.1\|4276113_4276686_+	hypothetical protein	NA	NA	NA	NA
AZB26654.1\|4276693_4278235_+	hypothetical protein	NA	NA	NA	NA
AZB27739.1\|4278283_4279255_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
AZB26655.1\|4279251_4280037_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AZB26656.1\|4280196_4281285_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZB26657.1\|4281408_4281624_+	hypothetical protein	NA	NA	NA	NA
AZB26658.1\|4282097_4282544_+	hypothetical protein	NA	NA	NA	NA
AZB26659.1\|4282549_4283476_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
AZB26660.1\|4283466_4283712_+	hypothetical protein	NA	NA	NA	NA
AZB26661.1\|4283823_4284036_+	hypothetical protein	NA	NA	NA	NA
AZB26662.1\|4284035_4284935_+	S49 family peptidase	NA	NA	NA	NA
AZB26663.1\|4285048_4285690_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AZB26664.1\|4285731_4288320_-	DNA gyrase/topoisomerase IV subunit A	A0A127AYR4	Bacillus_phage	6.9e-27	38.9
AZB26665.1\|4288328_4288745_-	hypothetical protein	NA	NA	NA	NA
AZB26666.1\|4288832_4290722_-	type IIA DNA topoisomerase subunit B	A0A172JHT4	Bacillus_phage	1.4e-66	31.9
AZB27740.1\|4290896_4291439_-	DUF2867 domain-containing protein	NA	NA	NA	NA
AZB26667.1\|4291743_4292892_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
AZB27741.1\|4293045_4293216_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
AZB26668.1\|4293246_4293441_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
AZB26669.1\|4293466_4293664_+	hypothetical protein	NA	NA	NA	NA
AZB26670.1\|4293739_4294504_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.2e-14	27.0
AZB26671.1\|4294591_4295530_-	AraC family transcriptional regulator	NA	NA	NA	NA
AZB26672.1\|4295675_4295882_+\|bacteriocin	bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_7

5099455 : 5145100

Bacillus_phage(41.67%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZB27305.1\|5099455_5099983_+\|transposase	transposase	A0A1B1P776	Bacillus_phage	3.5e-10	31.3
AZB27306.1\|5099862_5100810_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.4e-78	51.5
AZB27307.1\|5100863_5103374_-	M1 family peptidase	NA	NA	NA	NA
AZB27308.1\|5103397_5103616_-	hypothetical protein	NA	NA	NA	NA
AZB27309.1\|5103762_5105202_-	hypothetical protein	NA	NA	NA	NA
AZB27310.1\|5105303_5106098_-	thymidylate synthase	A6M9A2	Geobacillus_virus	1.0e-106	66.7
AZB27311.1\|5106222_5106906_-	hypothetical protein	NA	NA	NA	NA
AZB27312.1\|5106889_5107330_-	hypothetical protein	NA	NA	NA	NA
AZB27313.1\|5107436_5108786_-	1,4-alpha-glucan branching protein	NA	NA	NA	NA
AZB27314.1\|5108973_5109912_-\|transposase	DDE transposase	NA	NA	NA	NA
AZB27315.1\|5109941_5110286_-\|transposase	transposase	NA	NA	NA	NA
AZB27316.1\|5110428_5111022_-	hypothetical protein	NA	NA	NA	NA
AZB27317.1\|5111156_5112188_-	GHKL domain-containing protein	W8CYF6	Bacillus_phage	4.7e-27	32.8
AZB27318.1\|5112232_5112910_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.6e-38	38.2
AZB27319.1\|5113110_5115750_+	TonB-dependent receptor	NA	NA	NA	NA
AZB27320.1\|5115783_5116974_+	hypothetical protein	NA	NA	NA	NA
AZB27321.1\|5117055_5117475_-	hypothetical protein	NA	NA	NA	NA
AZB27322.1\|5117702_5118941_-	deaminase	NA	NA	NA	NA
AZB27323.1\|5119022_5119868_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZB27324.1\|5120239_5120911_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
AZB27325.1\|5120923_5122258_-	deaminase	NA	NA	NA	NA
AZB27326.1\|5122487_5122841_+	hypothetical protein	NA	NA	NA	NA
AZB27789.1\|5122893_5124183_-	glutamate-1-semialdehyde-2,1-aminomutase	NA	NA	NA	NA
AZB27327.1\|5124260_5125319_-	LysM peptidoglycan-binding domain-containing protein	Q332B8	Clostridium_botulinum_C_phage	2.8e-19	38.3
AZB27328.1\|5125334_5126243_-	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase	NA	NA	NA	NA
AZB27329.1\|5126587_5126914_-	hypothetical protein	F5A397	Riemerella_phage	1.0e-12	38.6
AZB27330.1\|5126954_5127137_+	hypothetical protein	NA	NA	NA	NA
AZB27790.1\|5127138_5127666_+	DUF4136 domain-containing protein	NA	NA	NA	NA
AZB27791.1\|5127952_5129746_+	T9SS C-terminal target domain-containing protein	A0A2D1GD28	Mycobacterium_phage	2.3e-05	41.8
AZB27331.1\|5129927_5130323_-	hypothetical protein	NA	NA	NA	NA
AZB27332.1\|5130306_5130867_-	LemA family protein	NA	NA	NA	NA
AZB27333.1\|5130866_5131649_-	hypothetical protein	NA	NA	NA	NA
AZB27334.1\|5131742_5132396_-	hypothetical protein	NA	NA	NA	NA
AZB27335.1\|5132399_5133458_-	hypothetical protein	NA	NA	NA	NA
AZB27336.1\|5133542_5133947_-	hypothetical protein	NA	NA	NA	NA
AZB27337.1\|5134140_5134419_-	DUF2752 domain-containing protein	NA	NA	NA	NA
AZB27338.1\|5134446_5135499_-	NADPH dehydrogenase NamA	NA	NA	NA	NA
AZB27339.1\|5135598_5136081_+	cytidine deaminase	NA	NA	NA	NA
AZB27340.1\|5136373_5136682_-	barnase inhibitor	NA	NA	NA	NA
AZB27341.1\|5136678_5137257_-\|protease	Zn-dependent protease	NA	NA	NA	NA
AZB27342.1\|5137384_5137846_-	ribonuclease N	NA	NA	NA	NA
AZB27343.1\|5137997_5138789_-	NAD(+) synthase	M1IPF8	Pelagibacter_phage	2.7e-51	46.6
AZB27344.1\|5138804_5139338_-	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	8.0e-39	46.8
AZB27792.1\|5139344_5139869_-	N-acetyltransferase	G9BWD5	Planktothrix_phage	4.2e-16	35.5
AZB27345.1\|5140514_5141549_+	gliding motility protein GldB	NA	NA	NA	NA
AZB27346.1\|5141686_5142010_+	gliding motility protein GldC	NA	NA	NA	NA
AZB27347.1\|5142113_5143253_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	4.4e-26	33.8
AZB27793.1\|5143322_5143769_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AZB27348.1\|5143882_5144395_+	DinB family protein	NA	NA	NA	NA
AZB27349.1\|5144671_5145100_+\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP033932

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection