CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP027755	Pseudomonas synxantha strain 2-79 chromosome, complete genome	3 crisprs	DEDDh,DinG,csa3,cas3,WYL,c2c9_V-U4,RT	1	0	6	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP027755_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP027755_1

2512428-2512539

Orphan

Consensus_repeat	Method
CCTGACAGCCGACCGCTAACTAACTGATGCCCCGCGATCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP027755_1

>merge|CP027755|1|2512428-2512539|CRISPRCasFinder
CCTGACAGCCGACCGCTAACTAACTGATGCCCCGCGATCCAAATGTGGGGGGCTTGCCCCCCGATAGCTGCCTGACAACCGACCGCTAACTAACTGATGCCCCGCGATCCAA

>CP027755|1|1|2512428-2512539|CRISPRCasFinder
CCTGACAGCCGACCGCTAACTAACTGATGCCCCGCGATCCAA	ATGTGGGGGGCTTGCCCCCCGATAGCTG
CCTGACAACCGACCGCTAACTAACTGATGCCCCGCGATCCAA

Protein	Signature genes	Signature genes Name	Protein_function
CP027755.1\|AZE60684.1\|2521690_2522320_+\|Transcriptional-regulator,-AcrR-family	unknown	unknown	gnl\|CDD\|224228
CP027755.1\|AZE60676.1\|2514271_2515363_+\|MocD	unknown	unknown	gnl\|CDD\|239588
CP027755.1\|AZE60670.1\|2507329_2507449_+\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE60673.1\|2509211_2510231_-\|Myo-inositol-2-dehydrogenase	unknown	unknown	gnl\|CDD\|275173
CP027755.1\|AZE60667.1\|2504109_2505099_-\|Transcriptional-regulator,-AraC-family	unknown	unknown	gnl\|CDD\|378976
CP027755.1\|AZE60683.1\|2520578_2521517_-\|Transcriptional-regulator,-AraC-family	unknown	unknown	gnl\|CDD\|227311
CP027755.1\|AZE60681.1\|2518855_2519728_-\|Undecaprenyl-diphosphatase	unknown	unknown	gnl\|CDD\|376891
CP027755.1\|AZE60668.1\|2505161_2506388_+\|putative-MFS-type-transporter	unknown	unknown	gnl\|CDD\|182309
CP027755.1\|AZE60675.1\|2513058_2514108_-\|Transcriptional-regulator,-LacI-family	unknown	unknown	gnl\|CDD\|380530
CP027755.1\|AZE60679.1\|2516917_2517736_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366542
CP027755.1\|AZE60677.1\|2515393_2515720_+\|Naphthalene-1,2-dioxygenase-system-ferredoxin-component	unknown	unknown	gnl\|CDD\|131430
CP027755.1\|AZE60665.1\|2502524_2503292_+\|3-oxoacyl-ACP-reductase	unknown	unknown	gnl\|CDD\|212491
CP027755.1\|AZE60674.1\|2510415_2512377_+\|sigma-54-dependent-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
CP027755.1\|AZE60678.1\|2515716_2516916_+\|Ferredoxin-reductase	unknown	unknown	gnl\|CDD\|170080
CP027755.1\|AZE60669.1\|2506430_2507261_+\|Glutathione-S-transferase	unknown	unknown	gnl\|CDD\|183298
CP027755.1\|AZE60672.1\|2508435_2509215_-\|Hydroxypyruvate-isomerase	unknown	unknown	gnl\|CDD\|226149
CP027755.1\|AZE60671.1\|2507489_2508416_-\|Sugar-ABC-transporter,-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380524
CP027755.1\|AZE60680.1\|2517786_2518740_+\|putative-dye-decolorizing-peroxidase-(DyP),-encapsulated-subgroup	unknown	unknown	gnl\|CDD\|367887
CP027755.1\|AZE60682.1\|2519776_2520415_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227915
CP027755.1\|AZE60666.1\|2503427_2504024_-\|Glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198314

Protein	Function_ID	Function_description	E-value
CP027755.1\|AZE60684.1\|2521690_2522320_+\|Transcriptional-regulator,-AcrR-family	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.27823e-13
CP027755.1\|AZE60676.1\|2514271_2515363_+\|MocD	gnl\|CDD\|239588	cd03511, Rhizopine-oxygenase-like, This CD includes the putative hydrocarbon oxygenase, MocD, a bacterial rhizopine (3-O-methyl-scyllo-inosamine, 3-O-MSI) oxygenase, and other related proteins. It has been proposed that MocD, MocE (Rieske-like ferredoxin), and MocF (ferredoxin reductase) under the regulation of MocR, act in concert to form a ferredoxin oxygenase system that demethylates 3-O-MSI to form scyllo-inosamine. This domain family appears to be structurally related to the membrane fatty acid desaturases and the alkane hydroxylases. They all share in common extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain eight histidine residues: HXXXH, HXXHH, and HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within homologs, stearoyl CoA desaturase and alkane hydroxylase.	1.02419e-139
CP027755.1\|AZE60673.1\|2509211_2510231_-\|Myo-inositol-2-dehydrogenase	gnl\|CDD\|275173	TIGR04380, hypothetical_protein_HOLDEFILI_04020, inositol 2-dehydrogenase. All members of the seed alignment for this model are known or predicted inositol 2-dehydrogenase sequences co-clustered with other enzymes for catabolism of myo-inositol or closely related compounds. Inositol 2-dehydrogenase catalyzes the first step in inositol catabolism. Members of this family may vary somewhat in their ranges of acceptable substrates and some may act on analogs to myo-inositol rather than myo-inositol per se. [Energy metabolism, Sugars].	1.19623e-117
CP027755.1\|AZE60667.1\|2504109_2505099_-\|Transcriptional-regulator,-AraC-family	gnl\|CDD\|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	1.5314e-25
CP027755.1\|AZE60683.1\|2520578_2521517_-\|Transcriptional-regulator,-AraC-family	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	7.42872e-92
CP027755.1\|AZE60681.1\|2518855_2519728_-\|Undecaprenyl-diphosphatase	gnl\|CDD\|376891	pfam02673, BacA, Bacitracin resistance protein BacA. Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteristic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.	4.10957e-87
CP027755.1\|AZE60668.1\|2505161_2506388_+\|putative-MFS-type-transporter	gnl\|CDD\|182309	PRK10213, nepI, purine ribonucleoside efflux pump NepI.	2.27536e-90
CP027755.1\|AZE60675.1\|2513058_2514108_-\|Transcriptional-regulator,-LacI-family	gnl\|CDD\|380530	cd06307, PBP1_sugar_binding, periplasmic sugar-binding domain of uncharacterized transport systems. Periplasmic sugar-binding domain of uncharacterized transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes.	8.64991e-82
CP027755.1\|AZE60679.1\|2516917_2517736_+\|hypothetical-protein	gnl\|CDD\|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	3.18612e-06
CP027755.1\|AZE60677.1\|2515393_2515720_+\|Naphthalene-1,2-dioxygenase-system-ferredoxin-component	gnl\|CDD\|131430	TIGR02377, putative_Rieske-like_ferredoxin_MocE, Rieske [2Fe-2S] domain protein, MocE subfamily. This model describes a subfamily of the Rieske-like [2Fe-2S] family of ferredoxins that includes MocE, part of the rhizopine (3-O-methyl-scyllo-inosamine) catabolic cluster in Rhizobium. Members of this family are related to, yet distinct from, the small subunit of nitrite reductase [NAD(P)H].	2.09363e-51
CP027755.1\|AZE60665.1\|2502524_2503292_+\|3-oxoacyl-ACP-reductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.51354e-64
CP027755.1\|AZE60674.1\|2510415_2512377_+\|sigma-54-dependent-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	1.04592e-154
CP027755.1\|AZE60678.1\|2515716_2516916_+\|Ferredoxin-reductase	gnl\|CDD\|170080	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional.	4.93242e-76
CP027755.1\|AZE60669.1\|2506430_2507261_+\|Glutathione-S-transferase	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	0
CP027755.1\|AZE60672.1\|2508435_2509215_-\|Hydroxypyruvate-isomerase	gnl\|CDD\|226149	COG3622, Hfi, Hydroxypyruvate isomerase [Carbohydrate transport and metabolism].	2.68357e-85
CP027755.1\|AZE60671.1\|2507489_2508416_-\|Sugar-ABC-transporter,-substrate-binding-protein	gnl\|CDD\|380524	cd06301, PBP1_rhizopine_binding-like, periplasmic binding proteins specific to rhizopines. Periplasmic binding proteins specific to rhizopines, which are simple sugar-like compounds produced in the nodules induced by the symbiotic root nodule bacteria, such as Rhizobium and Sinorhizobium. Rhizopine-binding-like proteins from other bacteria are also included. Two inositol based rhizopine compounds are known to date: L-3-O-methly-scyllo-inosamine (3-O-MSI) and scyllo-inosamine. Bacterial strains that can metabolize rhizopine have a greater competitive advantage in nodulation and rhizopine synthesis is regulated by NifA/NtrA regulatory transcription activators which are maximally expressed at the onset of nitrogen fixation in bacteroids. The members of this group belong to the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily.	2.88239e-115
CP027755.1\|AZE60680.1\|2517786_2518740_+\|putative-dye-decolorizing-peroxidase-(DyP),-encapsulated-subgroup	gnl\|CDD\|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	7.43336e-120
CP027755.1\|AZE60682.1\|2519776_2520415_+\|hypothetical-protein	gnl\|CDD\|227915	COG5628, COG5628, Predicted acetyltransferase [General function prediction only].	2.03996e-14
CP027755.1\|AZE60666.1\|2503427_2504024_-\|Glutathione-S-transferase	gnl\|CDD\|198314	cd03205, GST_C_6, C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 6; composed of uncharacterized bacterial proteins with similarity to GSTs, including Pseudomonas fluorescens GST with a known three-dimensional structure. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain. Though the three-dimensional structure of Pseudomonas fluorescens GST has been determined, there is no information on its functional characterization.	2.32484e-36

>CP027755.1|AZE60674.1|2510415_2512377_+|sigma-54-dependent-transcriptional-regulator
MSLTFSVQDLKYLTALGPAALNDGPVAALEQGWRACLSGQLERPAEVRQVIWDSWRRSVEAGIDPEDSHYRFVAAQALAATLANHRVLIAAAAQVMHGLLAYNPRGHINLTDAEGTTLYFCGLDITPVGSRLLESVQGTNCTGLALAEDRLMYVLAEENFAGALRQRRMHCAAAPIKDAQGLTLAMLTLTAEPGWFHFHTLGTVQAAAEAVSRQMALQVLLDEQHAVLEVLNEGLVVLDERGCIKALNRYARQLFGIGLELIGSPFQRLGRSELGGALGEPVRDLDCTFELHDRSQLACLVSVCPLEQGGVIVSVRENRRIREITRRLIGTQARYTFDTIQGTSRAIQDALHLGRIASRGDATTLILGESGTGKELFAQAIHNASERCSGPFVAVNCGAIPRDLVQSELFGHVEGAFTGSARGGSAGKFELADGGTIFLDEIGDMSFDAQVSLLRVLQEGEVTRVGAKNSRPVDVRIIAATHRNLSQAVAEGAFREDLYYRLNVLNLTVPPLRMRREDIPLLARHFLQRCVRSLRKPVQGFSPEALALLSAHGWPGNVRELENAIERATNLAMGELIQPADLPLETQQRETLRLYQPQPAQDLSSHELHAIVAALKNTGGNIRLAARQLNVSRGGLYNKMSRFGLDAGDFRGR
>CP027755.1|AZE60673.1|2509211_2510231_-|Myo-inositol-2-dehydrogenase
MSTQNIRLGLIGAGRMGSFHGLTAARHIPGACLAAIADPTPGQAARLAAELGVDKVYTDPQQLLDDPEIDGVLIAAPARSHAELVISAARAGKGIFCEKPMAITLDEADRAIAAAADARVPLQVGFNRRFAKSFRTAHLDVAAGRIGTPQLLRSLTRDPALNNPAASPQWVIFLETLIHDFDTLRYLNPGAEAVQVYVMADALIAPAYKSQGLLDTAVVTIRFDNGAIATAEANFQAVYGYDVRGEVFGSEGMLSMGSLNHCDLVRYLAEGIQADTQRMDTDLLRDAYIAELNHFVDCLRNGAKPLASGEDARAALAIARACIESYETGKSVAVQGARP
>CP027755.1|AZE60672.1|2508435_2509215_-|Hydroxypyruvate-isomerase
MMPFKLAVSAEMVFLDLPFIERVKRIHALGFSAEIWSWTDKDIDALAATGANFTSMTGYISGTLTDPGGSRQLLDSARESLGVAERLNCPSLNLHGTGLGAGGLPVQPVNQATGRMWLSACKTLEKIARLGEDAGRVFLLENLNTAVDHPGTPFARADETLALVQAVGSPHLKMNLDLYHAQIGEGNLIELIQRAGSAIGEIQVADVPGRKEPGTGEIHYPAIARALHAMGYTGVIGLEGWASGTSELALERFRQAFTL
>CP027755.1|AZE60671.1|2507489_2508416_-|Sugar-ABC-transporter,-substrate-binding-protein
MHRYSLLVAALLLLFSQWTFAAYRIGVSIARVDDNFMTYVRSGLEAAAKQQDVQIQFEDAQGDVVRQLNQVEGFLNQKVDAVIVLPVDTAATANITRAAVAAKTPLVYVNRHPDERTLPKGVVTVASNDIEAGQLQMRYLAEKLGGQGSVAIIMGDLAQNATHDRTEGARQVLKDFPGIKIVEQQSAEWQRNKGMDLTSNWLLAGTQFDAIVANNDEMAIGAAMALQQAGKAKGEIAIVGIDGLPDGLAAIKRGLLAASVFQDPKAQATQAVQAAIKMIKSEPIEAEVWVRFELIKPEQVAVFEQRYK
>CP027755.1|AZE60670.1|2507329_2507449_+|hypothetical-protein
MLAKNLQAPRSFSKHALSLTFFASKLAPTEGDDRLTDWH
>CP027755.1|AZE60669.1|2506430_2507261_+|Glutathione-S-transferase
MADYLPPKVWTWDTESGGTFASINRPIAGATHDKELPIGKHPLQLYSLATPNGQKVTILLEELLALGRTGAEYDAWLIKIGDGDQFGSGFVAVNPNSKIPALMDRSGATPIRVFESGAILQYLAEKFGAFLPSEPAARAECLSWLFWQMGSAPYLGGGFGHFYAYAPSKMEYPINRFAMEAKRQLDVLDKRLAVSEYIAGDEYTIADIAIWPWYGGLVKGRLYGDSAEFLSVHEYKHVLRWADAIDARPAVQRGRRVNRVSGEEQLPERHDASDLD
>CP027755.1|AZE60668.1|2505161_2506388_+|putative-MFS-type-transporter
MSEYAAQAPAGVVTEPAWLAVFSLAMGVFGLLTAEYLPASLLTPMALDLGVSEALAGQAVTVTAVVALFAGLLVPGLTRSIDRRVVLLGFSTLMIASNLLVALSSSLTVLLLMRILLGIALGGFWSMAAAVAMRLVPAASLPRALSIIFSGIAAGTVVAVPLGSYLGGLYGWRSAFIAAAAVGAVTLAFQAFTLPRLVPNGTARLRTVLEVLLRPGIAMGMFGCVLVHTAHFALFTYIRPFLESTTGVDTQGLALMLLGFGVANFVGTLLAGWLLVRHPRGTLVLMPVLVGIAALALVWLPVSLPGQALLLALWGMAFGGVPVAWSNWVARAVPDQAESAGGMVVASVQSAIAAGAAGGGLMFSISGIGGVFAGAGVLMLLAALLIALRVQVPRQDRDAGVTHHPSLV
>CP027755.1|AZE60667.1|2504109_2505099_-|Transcriptional-regulator,-AraC-family
MMQTLEFLTETPTMTAADAFTLSSDLINELLRGMRLRGVQYRRIQAGPTFGMGFGAKPGHAYFHFLAAGHVTLRGEDGDLFELSAGNAVFIAHGGAHALLSDASIDVQDIGDFDSAPLGDAVCAVDASPETVPNTLLFSACMEFELGSIQGLGNLMPALMLIDAGGQRYPGLMPILAVMEREVSTARIGFAGILARLADVVAAMIVRGWVECACGNASGLVAALRDPRLARALLALHQQPGRDWSVAQLAAQCHTSRSVFADRFQAILGIPPLRYATELRMRLASQWLTLERMPIETVAQRLGYTSQAAFSRAFKRITGQPPGAARSSM
>CP027755.1|AZE60666.1|2503427_2504024_-|Glutathione-S-transferase
MKLVGMLDSPYVRRVAISLDLYGVEFVHEPLSVFSTFAEFSQVNPVVKAPTLVLDDGTVLMDSSLILDYLETLAPADKKLLPQQPAARAHDLHLLGLALAACEKSVQIVYEHNLRPAEKLHAPWIERVSGQLLAAYALLDKQLDDGEALTQASITAAVAWSFSQFTVASVVKADAFPNLKRHAERLEQHPAFKRYPIA
>CP027755.1|AZE60665.1|2502524_2503292_+|3-oxoacyl-ACP-reductase
MTTQQAIYPDLKDKTVLISGGASGIGEFMVRAFAAQGAKVGFVDRAQSQGERLAALLNSKGFTVEFECCDITDEIGYRAAIGRFEQSLGPITVLVNNAANDVRHSLEEIDSQMFDRLIAVNLKHAFFAAKAVVPMMKEAGGGSIINLGSVGWMMASAGYPVYAASKAAAHGMTRGLARELGPSHIRVNTLVPGWVMTEKQLAMWVDDAARELIARSQCLPGSVMPEHIANMALFLASDASAMCSAQNFIVDGGWV
>CP027755.1|AZE60675.1|2513058_2514108_-|Transcriptional-regulator,-LacI-family
MHNHKRPTIATVAAHAGLSVATVDRVLNARAPVNPGTAEQVFQAAEAVGYFAARLIGQRIRERRPTYRFGVLLLGTAQAFYANLAQSISDAAQHHASANLSCQFDYINDRSPSAIVAQIEQLAVQCDALAVVSFAHPLINACLAQIRDAGVPVVALLSDIHEQALEPYVGQDNHVVGRTMGWLLAHTCGARKGSVGILLGGHRFLGHQARVKGLHSYLAEHAPGLKPLEPLINLDNCDITEEATLDLLARHTDLRGLCVVGGGGDGVINALAQLPKRPALCCILQESTELSRQALSRGLIDVVMDSQPRQTAAALVQLLVQLLNDEGFDPGRHRVHIPPQIVTSENMGT
>CP027755.1|AZE60676.1|2514271_2515363_+|MocD
MPEHTAYRARRDYSLTGPEAARAAEKGLVSASWYQSPISRKRMKELMQRRDGPALLDTAIWVSTLLVTGFGGYWFWGSWACVPFFLAYGVLYGTASNPRWHETGHGTAFKTRWMNDGLYQVACFMCLFEPHVWRWSHARHHTDTIVVGRDPEIVEPRPPSLWMMALSLFNLPLAWKTFSGVARHALGCMSAQEQNFIPETEWPKVFRAARIWIGIYALIIGTALYLHSWLPLMLVGLPSLYGAWLGYLFGLSQHVGLAEDVLDHRSNCRTIYMNRVLRFIYMNMNYHLEHHMYPMVPYHALEQLHDEIRSDCPPPYANLFEAYREIIATIRKQRSDPSYFVQRPIRPKAQSAPAALHAEASAG
>CP027755.1|AZE60677.1|2515393_2515720_+|Naphthalene-1,2-dioxygenase-system-ferredoxin-component
MNDQWIDVCAVGAIDPEDVLRFDHGAHTYAVFRSAEDEFFATAGLCTHEKIHLADGLVMDHVIECPKHNGRFDYRSGKALGAPVCVNLKTYPVRVEAGRVLLAVTAER
>CP027755.1|AZE60678.1|2515716_2516916_+|Ferredoxin-reductase
MSQALIIVGAGHAGGRAALTLREEGYTGRLILIGDEAHLPYERPPLSKGVLQGSTDLAGCSLCDNARLAALGIEHIAGNPVSRLDTQQHRLQLADGQWLTYTGLLLATGGRARRLPEAQAPVLYLRTHDEALALRDRLRSGTRVVVIGGGFIGLEVAATARGLGCEVTLLEAGPRLAGRVLPAPISAALLALHREQGVDVRLNVAVECIHADAVQLVDGQRLPCDLVVAGIGMQPNIELAAAAGLEVGQGIRVDAQLRTSAADIYAAGDVCEFRLAGVYQRQETWRNAEAQGRHAALNLLGRALPFETLPGFWSDQYDWGLQTVGVMTARTVSRALPGAGLLLFYLDDDARLQGACGWAPGNAAARDIKLCERLIAAGTVLNPGSLADADVSLKPLLRG
>CP027755.1|AZE60679.1|2516917_2517736_+|hypothetical-protein
MRQFLVFQSMWAMQTEPGSLDTQLDRIAAAGFDGVTDHYWTPAAVPRLHAAATARGLQIEGQLFPQSVDDLAAALEVISRYGCHHLTLQADVRPRAQAEAARLIEGWQRLAEQADFPILLETHRYRLTNDLLFTLDLLAQMPDLKLLADLSHYVVGRELPEPGALQDDEQIRTILRHSWGFHGRIASSEQVQVGLDFPQHQPWVERFTSWWRYGIDDWLTRADTPRSLSFTCELGPPPYAITDAKGRELTDRWAEALKMKALIRQVWASCHG
>CP027755.1|AZE60680.1|2517786_2518740_+|putative-dye-decolorizing-peroxidase-(DyP),-encapsulated-subgroup
MKTCPVQPPLEPQSVCHPITSSAIFMVATLAPDAVDNVRGWCADIAGLVRSVGKRVPSGNLTCVCGFGSDAWDRLFGAPRPAALHPFREFGVEGRKAVSTPGDILLHIRAEQMDLCFELATQLMAALGESVKVVDEVQGFRYFDMRSIIGFVDGTENPVGRKAERFTLVGDEDPQFEGGSYVLVQKYLHNMNAWNSLTVEAQEKVIGRTKLADIELDEEAKPSNSHSALTVITDENGEEVKILRDNMPFGRPGAGEFGTYFIGYARSPQPLEQMLENMFVGRPVGNYDRLLDFSTAVTGGLFFVPSADLLEELADRQ
>CP027755.1|AZE60681.1|2518855_2519728_-|Undecaprenyl-diphosphatase
MTNVCTAGLDVGFASLDYLQIFILGVIQGITELLPVSSTAHMRVVPALLGWQDPGSAFSAAMQLAALAAVVSYFWRDVRQVTTGSISAVRRGDYNDPWFKLAVAIVLATLPIGIAGLALSSTLNTCNSPLRGLMVIGIACVVMAILLALAEVRARYTRDVGQMRLRDALIVGVAQIGALIPGVSRSGSTLTAALFLNFKREEAARFSFLLGLPAIALAGLKELWVLLHADMPAHAWPHLIFGLVVASISAFFAIWGLMKFLERFSTWPFVIYRALLGVFLIVAVSTGLLT
>CP027755.1|AZE60682.1|2519776_2520415_+|hypothetical-protein
MFQEIGPGKRYLQSVQPIERIRQSIGVTGTFVNNGALRFFTESPMPETTVELIQTGPEDAELIRNLYQYYAYESSDWEQEDVEADGRFYIHDEHLTRYWHDPQWSANLLLVDGYIAGFLLIEGSELPGIDALELADLFILKRYRRKGIGRAIASQVLCSGESNWLVRFYDQDEVSQAFWRTVLDNLPRPVQTIELEDEPQLVSYLITRVSLH
>CP027755.1|AZE60683.1|2520578_2521517_-|Transcriptional-regulator,-AraC-family
MHSVALMVYPNFQSLSLSLGSVFECANLLRGEPAYEFHLVSESGGAVMTSQGFSVNTMAIRPEGYDTLIVSGYLEFRLPEANLLDLVKAASAQSRRVASLCMGIFVLAEAGLLEGKRTTTHWIHAPAFRKRYPDIRLEEDKLFVVDGQVWTGAGMSAGVDLALAMVENDLGSDLARRIARKLVIAQRRGSEQSQLSALLELDPKSDRVQLALAYAHENLTHDLSVEALADIARLSPRQFSRVFREETGQTPAKAIEALRVEAARAMMETSRHPVEVVARETGFGDRERMRQAFLRAFGQPPQAMQQVLFNPG
>CP027755.1|AZE60684.1|2521690_2522320_+|Transcriptional-regulator,-AcrR-family
MNHPSKSARQAILERGQSIVGAKGFSAVGLNEILQAAEVPKGSFYHYFNSKDAFGVVLLDTYFDHYVQGMQDLFDQPGLSHHAKLMRYWQCWIDNHTGCTDAGKCLAVKLGAEVSDLSEPMRLALQRGTARTIELLAVALQRGVEDGSLTFGQAPQNLAQRLYALWLGTSVMAKITRTTAPFAEALLLTRQLLGSPENPVIHFDRGTGK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP027755_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP027755_2

2893092-2893194

Orphan

Consensus_repeat	Method
TTGCCCCCGATGGCGGCCTGACAGCCGACCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP027755_2

>merge|CP027755|2|2893092-2893194|CRISPRCasFinder
TTGCCCCCGATGGCGGCCTGACAGCCGACCAGTATTTGACTGATGGTCTCGGTCCAGATGTGGGAGGGGGCTTGCTCCCGATGGCGGCCTGACAGCCGACCAG

>CP027755|2|2|2893092-2893194|CRISPRCasFinder
TTGCCCCCGATGGCGGCCTGACAGCCGACCAG	TATTTGACTGATGGTCTCGGTCCAGATGTGGGAGGGGGC
TTGCTCCCGATGGCGGCCTGACAGCCGACCAG

Protein	Signature genes	Signature genes Name	Protein_function
CP027755.1\|AZE60978.1\|2902853_2904842_+\|Alpha-amylase	unknown	unknown	gnl\|CDD\|200482
CP027755.1\|AZE60959.1\|2874864_2875332_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|215334
CP027755.1\|AZE60976.1\|2901535_2901775_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|314397
CP027755.1\|AZE60962.1\|2881248_2881761_+\|GCN5-related-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP027755.1\|AZE60960.1\|2876276_2880035_-\|TonB-dependent-receptor	unknown	unknown	unknown
CP027755.1\|AZE60968.1\|2891525_2893067_+\|Outer-membrane-factor-(OMF)-lipoprotein-associated-wth-MdtABC-efflux-system	unknown	unknown	gnl\|CDD\|273830
CP027755.1\|AZE60967.1\|2888421_2891529_+\|Multidrug-efflux-system-MdtABC-TolC,-inner-membrane-proton/drug-antiporter-MdtC-(RND-type)	unknown	unknown	gnl\|CDD\|182589
CP027755.1\|AZE60963.1\|2881846_2883136_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|274425
CP027755.1\|AZE60961.1\|2880195_2881095_-\|Transcriptional-regulator-of-various-polyols-utilization,-AraC-family	unknown	unknown	gnl\|CDD\|380381
CP027755.1\|AZE60965.1\|2884028_2885327_+\|Multidrug-efflux-system-MdtABC-TolC,-membrane-fusion-component-MdtA	unknown	unknown	gnl\|CDD\|183194
CP027755.1\|AZE60973.1\|2897856_2898312_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE60971.1\|2895954_2897046_+\|putative-Ig	unknown	unknown	gnl\|CDD\|276965
CP027755.1\|AZE60977.1\|2901894_2902392_+\|Mg(2+)-transport-ATPase-associated-protein-MgtC	unknown	unknown	gnl\|CDD\|224204
CP027755.1\|AZE60969.1\|2893256_2893388_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE60975.1\|2899940_2901350_-\|Type-cbb3-cytochrome-oxidase-biogenesis-protein-CcoG	unknown	unknown	gnl\|CDD\|274278
CP027755.1\|AZE60964.1\|2883295_2883796_+\|Thiol-peroxidase,-Tpx-type	unknown	unknown	gnl\|CDD\|179055
CP027755.1\|AZE60974.1\|2898389_2899799_-\|Transcriptional-regulator,-GntR-family-domain	unknown	unknown	gnl\|CDD\|224089
CP027755.1\|AZE60966.1\|2885323_2888425_+\|Multidrug-efflux-system-MdtABC-TolC,-inner-membrane-proton/drug-antiporter-MdtB-(RND-type)	unknown	unknown	gnl\|CDD\|182501
CP027755.1\|AZE60972.1\|2897099_2897846_+\|Oxidoreductase,-short-chain-dehydrogenase/reductase-family	unknown	unknown	gnl\|CDD\|180411
CP027755.1\|AZE60970.1\|2893776_2895846_+\|Sensory-box/GGDEF-family-protein	unknown	unknown	gnl\|CDD\|236645

Protein	Function_ID	Function_description	E-value
CP027755.1\|AZE60978.1\|2902853_2904842_+\|Alpha-amylase	gnl\|CDD\|200482	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins. GlgE is a (1,4)-a-D-glucan:phosphate a-D-maltosyltransferase, involved in a-glucan biosynthesis in bacteria. It is also an anti-tuberculosis drug target. GlgE isoform I from Streptomyces coelicolor has the same catalytic and very similar kinetic properties to GlgE from Mycobacterium tuberculosis. GlgE from Streptomyces coelicolor forms a homodimer with each subunit comprising five domains (A, B, C, N, and S) and 2 inserts. Domain A is a catalytic alpha-amylase-type domain that along with domain N, which has a beta-sandwich fold and forms the core of the dimer interface, binds cyclodextrins. Domain A, B, and the 2 inserts define a well conserved donor pocket that binds maltose. Cyclodextrins competitively inhibit the binding of maltooligosaccharides to the S. coelicolor enzyme, indicating that the hydrophobic patch overlaps with the acceptor binding site. This is not the case in M. tuberculosis GlgE because cyclodextrins do not inhibit this enzyme, despite acceptor length specificity being conserved. Domain C is hypothesized to help stabilize domain A and could be involved in substrate binding. Domain S is a helix bundle that is inserted within the N domain and it plays a role in the dimer interface and interacts directly with domain B. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
CP027755.1\|AZE60959.1\|2874864_2875332_+\|hypothetical-protein	gnl\|CDD\|215334	PLN02623, PLN02623, pyruvate kinase.	0.00686751
CP027755.1\|AZE60963.1\|2881846_2883136_-\|sugar-transferase	gnl\|CDD\|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	7.14731e-18
CP027755.1\|AZE60962.1\|2881248_2881761_+\|GCN5-related-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.82969e-14
CP027755.1\|AZE60977.1\|2901894_2902392_+\|Mg(2+)-transport-ATPase-associated-protein-MgtC	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	9.89997e-45
CP027755.1\|AZE60968.1\|2891525_2893067_+\|Outer-membrane-factor-(OMF)-lipoprotein-associated-wth-MdtABC-efflux-system	gnl\|CDD\|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	1.42861e-114
CP027755.1\|AZE60967.1\|2888421_2891529_+\|Multidrug-efflux-system-MdtABC-TolC,-inner-membrane-proton/drug-antiporter-MdtC-(RND-type)	gnl\|CDD\|182589	PRK10614, PRK10614, multidrug efflux system subunit MdtC; Provisional.	0
CP027755.1\|AZE60970.1\|2893776_2895846_+\|Sensory-box/GGDEF-family-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	2.22215e-123
CP027755.1\|AZE60961.1\|2880195_2881095_-\|Transcriptional-regulator-of-various-polyols-utilization,-AraC-family	gnl\|CDD\|380381	cd06976, cupin_MtlR-like_N, AraC/XylS family transcriptional regulators similar to MtlR, N-terminal cupin domain. MtlR is a Pseudomonas fluorescens protein that acts as a transcriptional regulator of the mannitol utilization genes. It has an N-terminal cupin domain (represented by this alignment) and a C-terminal AraC/XylS family helix-turn-helix (HTH) DNA-binding domain. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	3.07442e-38
CP027755.1\|AZE60965.1\|2884028_2885327_+\|Multidrug-efflux-system-MdtABC-TolC,-membrane-fusion-component-MdtA	gnl\|CDD\|183194	PRK11556, PRK11556, MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit.	3.26599e-146
CP027755.1\|AZE60971.1\|2895954_2897046_+\|putative-Ig	gnl\|CDD\|276965	sd00038, Kelch, Kelch repeat. Kelch repeats are 44 to 56 amino acids in length and form a four-stranded beta-sheet corresponding to a single blade of five to seven bladed beta propellers. The Kelch superfamily is a large evolutionary conserved protein family whose members are present throughout the cell and extracellularly, and have diverse activities. Kelch repeats are often in combination with other domains, like BTB and BACK or F-box domains.	5.32895e-28
CP027755.1\|AZE60976.1\|2901535_2901775_-\|hypothetical-protein	gnl\|CDD\|314397	pfam11462, DUF3203, Protein of unknown function (DUF3203). This family of proteins with unknown function appears to be restricted to Gammaproteobacteria.	2.27174e-20
CP027755.1\|AZE60975.1\|2899940_2901350_-\|Type-cbb3-cytochrome-oxidase-biogenesis-protein-CcoG	gnl\|CDD\|274278	TIGR02745, iron-sulfur_cluster-binding_protein, cytochrome c oxidase accessory protein FixG. Member of this ferredoxin-like protein family are found exclusively in species with an operon encoding the cbb3 type of cytochrome c oxidase (cco-cbb3), and near the cco-cbb3 operon in about half the cases. The cco-cbb3 is found in a variety of proteobacteria and almost nowhere else, and is associated with oxygen use under microaerobic conditions. Some (but not all) of these proteobacteria are also nitrogen-fixing, hence the gene symbol fixG. FixG was shown essential for functional cco-cbb3 expression in Bradyrhizobium japonicum.	0
CP027755.1\|AZE60964.1\|2883295_2883796_+\|Thiol-peroxidase,-Tpx-type	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	2.57469e-103
CP027755.1\|AZE60966.1\|2885323_2888425_+\|Multidrug-efflux-system-MdtABC-TolC,-inner-membrane-proton/drug-antiporter-MdtB-(RND-type)	gnl\|CDD\|182501	PRK10503, PRK10503, MdtB/MuxB family multidrug efflux RND transporter permease subunit.	0
CP027755.1\|AZE60972.1\|2897099_2897846_+\|Oxidoreductase,-short-chain-dehydrogenase/reductase-family	gnl\|CDD\|180411	PRK06123, PRK06123, SDR family oxidoreductase.	3.65484e-119
CP027755.1\|AZE60974.1\|2898389_2899799_-\|Transcriptional-regulator,-GntR-family-domain	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	9.53507e-151

>CP027755.1|AZE60968.1|2891525_2893067_+|Outer-membrane-factor-(OMF)-lipoprotein-associated-wth-MdtABC-efflux-system
MTDSINAPATPVGASLLAKNAHTPRSSRRNALSLTAFASKLAPTVGLVMLLSACAIGPDYQRPEVIEPVQFKEAQGWRQANPSDSLARGAWWELYGDRQLNDLVVRLNTSNQTVAQAEARFRQAKALVRSSRGAFYPSVDLSVGKTRASQGTGSSSASLSSSSSGIRDTLNAQLGVSWEADIWGKLRRGLEANEASAEASSADLAAMRLSQQSELVQSYLQLRVMDEQTRLLQATLDTYQRSLKMTENQYRAGVAGKDAIAQAQTQLKTTQASLIDLIWQRAQLENAIAVLIGEAPANFNLAVSKEIPALPQIPVSLPSQLLERRPDIASAERSVIAANANIGVAKAAYYPDLSLSMQGGYSSSTYEDWISLPNRFWSVGPKLAMTLFDGGQRSAEVDRTVASYDETVAKYRQTVLDGFREVENYMVQLKVLADEAVVSNEALESARESLRLTENQYKAGLIAYLDVVTVQATALSNERTVLNLLQSRLVASVQLIAALGGGWDGQTSLAEKE
>CP027755.1|AZE60967.1|2888421_2891529_+|Multidrug-efflux-system-MdtABC-TolC,-inner-membrane-proton/drug-antiporter-MdtC-(RND-type)
MNLSGPFIRRPVATMLLSLAIMLLGGVSFNLLPVSPLPQIDFPVIVVSASLPGASPEVMASSVATPLERSFGSIAGITTMSSSSSQGSTRVILAFDSDRDINGAAREVQAAINASRNLLPSGMRSMPTYKKINPSQAPIMVLSLTSDVLQKGQLYDLASTILSQSLSQVPGVGEVQIGGSSLPAVRIELEPKALDQYGVALDDVRNTIANANQRRPKGSLEDGERNWQIQANDQLEKAKDYEPLLIRYQDGAALRLRDIAKITDGVEDRYNSGFFNNDSAVLLVINRQSGANIIETVRQIKAQLPALQAVLPSSVKLSLAMDRSPVIAATLHEAEMTLLIAVGLVILVVYLFLGNFRASLIPTLAVPVSLVGTFAVMYLYGFSLNNFSLMALILATGLVVDDAIVVLENISRHIDEGVPPMKAAYLGAQEVGFTLLSMNVSLVAVFLSILFMGGIVTNLFREFSITLSAAIIVSLIVSLTLTPMLCARWLKPHDKNQQTGLQRWSQKINDRMVAGYATSLDWVLRHRRLTLLSLLLTIGLNVALYVVVPKTFMPQQDTGQLIGFVRGDDGLSFNVMQPKMEIFRQAVLKDPAVLSVAGFIGGNNGTNNAVMLVRLKPISERKISAQAVIERLRKDVPPVPGGRLFLMADQDLQFGGSRDQTSAQYSYILQSGDLAALRLWYPKVVAAMRELPELTAIDAREGRGAAQVTLIVDRDQAKRLGIDMDMVTAVLNNAYSQRQISTIYDSLNQYQVVMEVNPKYAQDPITLNQVQVITADGARVPLSTIAHYENSLADDRVSHEGQFASENIAFDMAPGVTVEQGTAAIERAIAKVGLPEDVIAKMAGTADAFAATQKGQPFMILGALVAVYLVLGILYESYIHPLTILSTLPSAGVGAMLAIYLTGGEFSLISLLGLFLLIGVVKKNAILMIDLALQLERNDGMGPLESIRSACLLRLRPILMTTLAAILGALPLLLGSGDGAEMRRPLGLTIIGGLVFSQILTLYTTPVVYLYLDRARHRFNAWRGVRTDAALDTAL
>CP027755.1|AZE60966.1|2885323_2888425_+|Multidrug-efflux-system-MdtABC-TolC,-inner-membrane-proton/drug-antiporter-MdtB-(RND-type)
MNLSRLFILRPVATTLSMLAIVLAGIISYRLLPVSALPQVDYPTIRVMTLYPGASPDVMTSAVTAPLERQFGQMPGLTQMASTSSGGASVLTLRFNLDINMDVAEQQVQAAINAATNLLPKDLPAPPVYNKVNPADTPVLTLAITSKTMLLPKLNDLVDTRMAQKIAQISGVGMVSIAGGQRQAVRIKVNPEALAANGLNLSDVRSLIAASNVNQPKGNFDGPTRVSMLDANDQLVSPEQYAELILAYNNGAPLRLKDVAQIVDGAENERLAAWANENQAVLLNIQRQPGANVIEVVDRIKALLPSITDNLPAGLDVTVLTDRTQTIRASVKDVQHELLIAIALVVMVTFLFLRRVSATIIPSIAVPLSLVGTFGVMYLAGFSINNLTLMALTIATGFVVDDAIVMLENISRYIEEGETPMAAALKGAKQIGFTLVSLTLSLIAVLIPLLFMADVVGRLFREFAITLAVAILISLVVSLTLTPMMCARLLKREPKEEEQGRFYKASGAWIDWLIEAYGRKLQWVLKHQPLTLLVAIATLGLTVVLYLVVPKGFFPVQDTGVIQGISEAPQSISFAAMSQRQQELAKIILADPAVESLSSYIGVDGDNATLNSGRLLINLKAHGQRDLSAAQVITRLQPEIDKLVGIRLFMQPVQDLTIEDRVSRTQYQFSMSSPDAELLALWSGKLVHALSQLPELTDVASDLQDKGLQVYLVIDRDAASRLGVNVATITDALYDAFGQRQISTIYTQASQYRVVLQAQSGETLGPAALNQIHVKTTDGGQVRLSSLAHVEQRQAQLAIAHIGQFPAVMMSFNLAPGVALGKGVELINQTQKDIGMPVGVQTQFQGAAQAFEASLSSTLLLILAAVVTMYIVLGVLYESYIHPITILSTLPSAAVGALLALLLSGNDLGMIAIIGIILLIGIVKKNAIMMIDFALDAERNQGLDPQTAIYQAALLRFRPILMTTLAALFGAVPLMLASGSGAELRQPLGLVMVGGLLVSQVLTLFTTPVIYLYFDRLGRRWRKEPQRLEPVEP
>CP027755.1|AZE60965.1|2884028_2885327_+|Multidrug-efflux-system-MdtABC-TolC,-membrane-fusion-component-MdtA
MVDHSMQSSPRKSRRWLFGLLVLLVIAGLCWKFWPSGAAHKDAPAGHTGKTGMARPGFGGSTGPVPVRVAPAVLGEFPVYYKALGTVTALNTINVRSRVGGELMKIAFEEGQMVKAGDLLAEIDPRSYQNALLQAQGTLLQNQAQLKNAQVDVERYRGLYAQDSIAKQTLDTAEALVLQYQGTVKTNQGAVDDARLNLEFTKIRAPISGRVGLRQLDVGNLVAANDTTALAVITQTQPISVAFTLPENTLETVLARYHAGNKLPVEAWDRGDTKKQAVGVLQSLDNQIDVTTGTLKFKARFDNKDQALFPNQFVNVHLLADTLHNVVLAPSAAIQFGNTGTFVYKLDGDNKVKVQPLVLGDTDGDNTVIKEGLVAGDRVVLEGTDRLKDGSEIEVVNDSSEVPTAPTEHLQGKPAAKGETGADAGKAQKVGS
>CP027755.1|AZE60964.1|2883295_2883796_+|Thiol-peroxidase,-Tpx-type
MAQVTLKGNPVQVEGELPKVGAKAADFTLTAGDLSNATLATFAGKRKVLNIFPSVDTPTCATSVRKFNAQANDVENTVVLCISTDLPFAQARFCGSEGLENVKNLSDFRDSDFAVDYGVAIADGPLKGLTARAVVVLDENDNVLHSELVKEIAEEPNYDAALAVLK
>CP027755.1|AZE60963.1|2881846_2883136_-|sugar-transferase
MNQPATKVLVIGYVWPEPRSSAAGGHMMQILESFLTQGWDITFSSPATIGEHKADLPALGIAECAIELNNSSFDDFIRELAPDIVLFDRFMMEEQFGWRVEQCCPDALRVLETSDLQSLRDARHQRFKEQLKAHPDGDDFTALFAPALEEEFQRMADTDLAKREIAAIYRCDISLMISDVEIRLLTEQFKVPAALLHWCPLMLQPPTAAFAPFEDRAHFLSIGNFRHAPNWDAVLWMKHSLWPLIRQQLPGAQLHIYGAYTPPKATALHNPAQGFHVMNWAEDALQVMTAARICLAPLRFGAGIKGKLIDAMLCGTPNVTTPIGAEAMGDDQHWPGVIAQDAPALAAAAVALYQDRERWTQAQEHGRQLLARRYDQALHGPALVECLEQCRRNLAAHRRDNFTGSMLRHHAHKSTQYMSQWIEAKNRNI
>CP027755.1|AZE60962.1|2881248_2881761_+|GCN5-related-N-acetyltransferase
MIRDARSSDANGIASVHVSSWQQAYLDLMPADFLASLTATLPKREAAWARAIESKASDVFVSEVDGKVTGWISVGPCRDEDKACAEAGEVMAIYVLAEYWGKGIGAKLWASGFKRLVDQGYKVITLWVLAENHRAVRFYQGLGGREELGSRRTLVRGGVSLEEVRYVWER
>CP027755.1|AZE60961.1|2880195_2881095_-|Transcriptional-regulator-of-various-polyols-utilization,-AraC-family
MTRATRITDPSYELMDDHNGLSIIYRQHGFPCPLVRWHFHKEYELHLIVASSGKVFIGDYIGNFYPESLFLTGPNLPHNWISQVEEGEVVPKRDMLVNFTDELFEQGSHTFAELKSLAPLLERAQYGIEFRSKKTIAQAMALMQRIEEAQGMARLGHFFILLEVLSACDDYQLLSGVTTPQQADEHSIDRTNRAVDYIFAHYARELPLEEVAEYLGMKPTYFSRVFKQATGRTFIEFVNRLRISKSCELLADGDKAVTDVCFESGFNNISNFNRRFQQLKGMTPSLYRRLAVQRLTEQI
>CP027755.1|AZE60960.1|2876276_2880035_-|TonB-dependent-receptor
MSDRPLNPDNDQPPRAAGNPSLPVVYTADQSRPVTPRATDLDDPYSAFPSIPLLFTPYFENAVYGLGIRHVRPYALFVFEAWFNRSTNDYFAIYLDDLVFPVADDLVEDLDFDRHGLAVPEEFVPEGEVLSYGRVRRAASGTESVSVPQLILIKTTRPGGVDTDPGSPWHTGLVMCVEGFDEGATIGVGDVVNGLYCLIDMYENCRQNDVIELSWDGVFVLHAVSPEEAAGMGPIRVFVDKSIIDRGGQLGTLTLRFRVRDVVENFSGEKYQYSKPYFLNAELDPSLLWPPIFLVDGEELVSRQIDFDTQSGSTFEILILTPRQVPTPVPRHQITALLLCTLEDGSVVPVSLGPVIDANLTFTFIEVDPEIIALVVGGSLRVAFVWETADGMLLGQSGSITITVVGTKVLMPAPDVSPIELGLIPVGETITVTIPHYEPHDPSWLETLYITHVPPGGGGALIYSQPQLAGSQGGTYTVSAADMAQFNGRGDIRIYYETNDGAAHILGGNALAIRQSAMLGAQVGERTADMPAPRLQGAIGNNVDPADVPGNDVLVTFTYLGTQAGDKLHWSCIGSGLGGSDNGTIIINSATAGKELPYPVSRDILDKNNNGSLRISYSLERDGPPRVVLRSEILALTVGKGVQLDRPIIVGASISPDELNPLAAVNGTRVIARFRPMLATDAIDIDWLTADGHGSVVKNVAGDPATNEVSVLIDARTIAQGIREGGNSIDVLYRFHRGTFPYESLTVPLRLLPLTGLPTPTIEGISGPILDVSQLSPLARTYIIVWSFIHAAQLIWMTYESGGVVIEETYTANEVTDDGVLNGINPPTPVDKIKLLEEGADLTIRFWVSLAESADKNTAVQFGVRHYIIQALPGVLPHPLINGTTDTGPNVTVDPLPIEHNTTVTVRYTGMSGRDRITLCWYFDDGTCHSVIENGLDGGTKIFNLTADKVLHRSVNSTVCLRYSVVRNGSGEPIPSNVQTVRVNTILPADLPQPRINNIAPGGTLDVNAFSGNGLASLIKWALSKDGQRAWITCRSAGVAPLHVLTADGALVSSAEAANGLANKPVLRSWLTGLANNAQFSVTAEVDFYGRRDKSKVINFSNTTYTIKPEGKLSEDFETANYHDLFYTGVPVQFPALTLLFLRGRGYISRAYPEYHHPYLTNLYVITSQFTELKITLETAARSLKFGIGINSDESARVDYWGDTGYIGSNYYYRANGHWQWVNFTAPTGNITELKITINNGSVNLDNFTFTY
>CP027755.1|AZE60959.1|2874864_2875332_+|hypothetical-protein
MISRLVGGLGFSYNELVGQGLIQNLPLKRLFDASDNEELIQNPVPGVKLWFWEETKRLDQVMIILIQTVGQPVYSGQLPQPFKLDMDQQYVREVLGVPTETKPSVKLPGGLGGRGGTDIYYLDQRVHSNVMVTLSYLENLRVNNISFSLINSGHD
>CP027755.1|AZE60969.1|2893256_2893388_-|hypothetical-protein
MDGAWRRPPKSMSDYAHTEPKRGAEWWGKSALVTFALFESDPL
>CP027755.1|AZE60970.1|2893776_2895846_+|Sensory-box/GGDEF-family-protein
MLIGSYSTSLVVISLCVAVLASYTALDLAGRIATAKGRAVYLWISGGALAMGVGVWSMHFIGMLALRLPFALGFDLGITALSLLIAVLSSGFALWLVSQPRLTAWQLAFGALVMGAGIASMHYTGMAAMRMTPGIDYDPTLFGASLLIAVMACGAALWIAFNLRRNTPYVRLARGGAAVVMGVAIVGMHYTGMAAARFADGSYCGAALTGLSGKGLDNLVLVTSLAVLVIALLTSLLDARLEARTAVLADSLTLANQELTHLALHDMLTGLPNRTLLTDRIQQGIQAVNEQGGCFALMFIDLDGFKPVNDAFGHHMGDQLLREVGLRLREDLRSQDTLARIGGDEFVLLVQLTQPDDAMGLAERQVGLINRTFKVAEQELNISASIGIALFPGNGSSPQELLMNADAAMYHAKGMGKNGYSFFDVSMNTNARKQLQLLQDLRNALEHGQFRLYYQPKFDAVSGAAVGAEALLRWEHPQQGLLLPATFIALAEKTGLIIPIGEWVLNEACRQMSLWYAQGYESWRIAVNLSALQFCHAGLVNSVAAALERHQLPANSLTLEITETTAMSDADASMTVLQQLSDMGVDLSIDDFGTGYSSLMYLKRLPANELKIDRGFVRDLEHDSDDAAIVSAIVALGQALGLRIVAEGVETDVQQDFLTRLGCDSLQGYLLGHPLPADQFIADIQKATG
>CP027755.1|AZE60971.1|2895954_2897046_+|putative-Ig
MNANLAGEFKDTGSMLEPRYFHCAVTTELGVLVIAGSGGIELYNSLSQEWSARAVLPVARHTCGAVILRPGVVLVAGGSDAGNALRDAQLYDVAADCWRAASPLHTPRFGHTTTLLESGRVLVVGGNNLGPSGGQVQDSVELYDPLGDLWHRQGWLPVDAMNHTATLLPDANLLVVGGFSGRQNAALANAFIYDVASGQWAPVRPMPMPLMQHTATLLLDGRVLVAGGANEPFGPAQNHACIYDPAADSWELSEMCVPRKDHTATRLAAGQVLVVGASDISNPENARTAELYDPLSGQWVLTAQMPHGRFGHSASCLPTGEVLVAGGARPISHPAPVSGAEIYTLARVSHQGASTWAGVKPSR
>CP027755.1|AZE60972.1|2897099_2897846_+|Oxidoreductase,-short-chain-dehydrogenase/reductase-family
MDKVVIITGGSRGIGAETALLAAREGYRICINYQSDEKAAQGMLEQVRGLGAQAIAVRADVSSEDEVIALFNRVDTELGRVTALVNNAGTVGQKSRVDEMSEFRLLKIMKTNVLGPILCAKHAVLRMSPRHGGQGGSIVNVSSVAARLGSPGEYVDYAASKGALDTFTLGLSKEVAGEGIRVNAVRPGYIFTDFHALSGDPDRVSKLESGIPMARGGRPDEVAEAIIWLLSDKASYATGTFLDLGGGR
>CP027755.1|AZE60973.1|2897856_2898312_-|hypothetical-protein
MRINMLPASTAYQLGEGRPENNWLAVPAAPEEPPFADRRSARQIIKDNPGVKHLLRRMDSYPVTDLLKRRLGDWTSANPDARARARAAYNLARVINVLDNVNDRRVGNSERHDGKINGFYNAGYSTRKNSEARLLVAFAQDGYDVLQNLGH
>CP027755.1|AZE60974.1|2898389_2899799_-|Transcriptional-regulator,-GntR-family-domain
MKRYEKFADDIAELIRSGVLGPGQRVPSVRYASQTYGVSPSTVFQAYYLLERRGLIRARPRSGYFVNTHAPSPFSEPVVSAQVHESTHVDVSELVFSVLDSIKDPNTVPFGSAFPSPMLFPLPRLARSLASASREMDPRLVVTDMSPGNPQLRRQIALRYMVGGLMLPMEELLITNGALEALNLCLQAVTEPGDLVAIEAPAFYACLQVLERLKLKAVEIPVHPRDGIDLDALAQSLERYPIKACWTMTSFQNPMGATLPEAKKQALVELLRGHQVPLIEDDVYAELYYGQQAPKPAKAFDTEGLVMHCGSFAKSLAPGYRVGWVAAGRFAQKVERLKLMTSLCPSMPAQAAIADYLQHGGYDRHLRKLRYALEEQQSAMLAAIARYFPAQTRVSQPAGGYFLWLELPEQTDSLKLFQMALAQGISIAPGPIFSATRRFSNCIRLNYGSPWTEASEKAMETLGRIVRSF
>CP027755.1|AZE60975.1|2899940_2901350_-|Type-cbb3-cytochrome-oxidase-biogenesis-protein-CcoG
MSERIPTVETFEPNHPKKVKAKSSDNLIHTRSFTGAFRTLRVGGAGLLFLAFFGTVWLNWGGRQAVLWDLAESKFHIFGATFWPQDFILLSALLIICAFGLFAITVFAGRVWCGYTCPQSSFTWLFMWCEKVTEGERNQRIKLQAAPWSLNKLARRSAKHTLWLGISLLTGLTFVGYFTPIRPLAAELLTWQMGGVSLFWVLFFTGATYINAGWLREAVCMHMCPYARFQSVMFDKDTLTISYDTARGERRGPRKREVQPAEVGLGDCIDCQLCVQVCPTGIDIRDGLQMECIGCAACIDACDSIMDKMGYARGLVSYTSEHQLQGGKTHLLRPRLIGYSAVLLVMIAALVVALVERPMVSLDVTKDRGMFRENSQGLIENIYSLKVINKTQQRQDYRLELVDADDFQLQGKTQVSLAPGEIVDVPVSVALLADKPVSSSQTIRFKVTDVDEPWIYSAADSRFVAPLNR
>CP027755.1|AZE60976.1|2901535_2901775_-|hypothetical-protein
MSVRIENHLCYFTLDKTGKEQSLPATRVNILTDNDKAMSYVELAGEQIYITEAEADALTVEGAKDGRNHVKAEKPGSVI
>CP027755.1|AZE60977.1|2901894_2902392_+|Mg(2+)-transport-ATPase-associated-protein-MgtC
MDAWWHQVWQTLQAEFADIGDARQLTQITVRLLIAALLGGILGFEREQKGKAAGVRTHMLVALGAALFVLVPQMSGNQADAMSRVVQGVIAGIGFLGAGTILKGKEDEEGQHVKGLTTAAGLWMTAAIGVAAGMGRESTAVLSTLLALAVFSVMPRVVKLLEKDE
>CP027755.1|AZE60978.1|2902853_2904842_+|Alpha-amylase
MTAETLAPEDCALPLSQALLLPRIAIESTMPVIDNGEFAVKAVVGQRVNVTSKVFADGHDKLAVLIRWRAREDESWHSVVMTDVGNNGWEGAFSVAQQSPHEYCIEAWIDTFASFCYELRKKHEAGVPVSLELQEGRSLVLQAAERSDNELRDRLMILHHELSGLLETEQVALFLHEDSAHLMTQADHRAYLSVSPVYPIDVEREAAQFASWYELFPRSITDDPARHGTFNDVHSRLSMIHDMGFDVLYFPPIHPIGRSHRKGKNNSLTAGPDDPGSPYAIGSEEGGHEAIHPQLGSRDDFRRLVKAAADHGLEIALDFAIQCSQDHPWLKQHPGWFNWRPDGTIKYAENPPKKYQDIVNVDFYAADAIPGLWTELRDIVVGWVEEGVKTFRVDNPHTKPLPFWQWLISDVRTKYPEVIFLAEAFTTPAMMARLGKVGYSQSYTYFTWRNTKAELSEYLTQLNQSPWRECYRPNFFVNTPDINPAFLHQSGRPGFLIRAALATMGSGLWGMYSGFELCEAAPVPGKEEYLDSEKYEIRPRDFTAPGNIIAEIAQLNRIRRQNPALQTHLGLKLYNAWNDNILYFGKRSEDGSNFILVAVNLDPFNAQEAHFELPLWEMGLPDDAQTQGEDLMNGHRWTWYGKTQWTRLEPQMPFGIWRITAG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP027755_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP027755_3

4873471-4873581

Orphan

Consensus_repeat	Method
GGGGTGCGCTCTAACCAACTGAGCTACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP027755_3

>merge|CP027755|3|4873471-4873581|CRISPRCasFinder
GGGGTGCGCTCTAACCAACTGAGCTACAGACCCAATTTCGAGCTGCTAAGGCCGACCTCACCCTGCTCCTTACCACAGAGCATGGGGTGCGCTCTAACCAACTAAGCTACA

>CP027755|3|3|4873471-4873581|CRISPRCasFinder
GGGGTGCGCTCTAACCAACTGAGCTACA	GACCCAATTTCGAGCTGCTAAGGCCGACCTCACCCTGCTCCTTACCACAGAGCAT
GGGGTGCGCTCTAACCAACTAAGCTACA

Protein	Signature genes	Signature genes Name	Protein_function
CP027755.1\|AZE62812.1\|4863651_4864479_-\|Chemotaxis-protein-methyltransferase-CheR	unknown	unknown	gnl\|CDD\|224271
CP027755.1\|AZE62820.1\|4877205_4877838_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE62826.1\|4879822_4880086_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE62811.1\|4862941_4863349_-\|Flagellar-basal-body-rod-protein-FlgB	unknown	unknown	gnl\|CDD\|180196
CP027755.1\|AZE62822.1\|4878066_4878192_+\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE62823.1\|4878188_4878425_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379462
CP027755.1\|AZE62818.1\|4868181_4869570_-\|putative-MFS-type-transporter	unknown	unknown	gnl\|CDD\|341030
CP027755.1\|AZE62815.1\|4866434_4866758_+\|Negative-regulator-of-flagellin-synthesis-FlgM-(anti-sigma28)	unknown	unknown	gnl\|CDD\|274802
CP027755.1\|AZE62819.1\|4875997_4877209_+\|site-specific-recombinase,-phage-integrase-family	unknown	unknown	gnl\|CDD\|271177
CP027755.1\|AZE62814.1\|4865597_4866293_+\|Flagellar-basal-body-P-ring-formation-protein-FlgA	unknown	unknown	gnl\|CDD\|180794
CP027755.1\|AZE62821.1\|4877866_4878070_+\|excisionase,-putative	unknown	unknown	gnl\|CDD\|378935
CP027755.1\|AZE62816.1\|4866806_4867277_+\|Flagellar-biosynthesis-protein-FlgN	unknown	unknown	gnl\|CDD\|377465
CP027755.1\|AZE62828.1\|4880389_4880620_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE62817.1\|4867373_4868123_+\|Flagellar-brake-protein-YcgR	unknown	unknown	gnl\|CDD\|227868
CP027755.1\|AZE62825.1\|4879361_4879826_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE62810.1\|4862494_4862938_-\|Flagellar-basal-body-rod-protein-FlgC	unknown	unknown	gnl\|CDD\|235556
CP027755.1\|AZE62824.1\|4878488_4878893_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379352
CP027755.1\|AZE62827.1\|4880082_4880361_-\|hypothetical-protein	unknown	unknown	unknown
CP027755.1\|AZE62813.1\|4864522_4865455_-\|Chemotaxis-protein-CheV	unknown	unknown	gnl\|CDD\|381151
CP027755.1\|AZE62809.1\|4861758_4862478_-\|Flagellar-basal-body-rod-modification-protein-FlgD	unknown	unknown	gnl\|CDD\|235847

Protein	Function_ID	Function_description	E-value
CP027755.1\|AZE62812.1\|4863651_4864479_-\|Chemotaxis-protein-methyltransferase-CheR	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	3.36429e-103
CP027755.1\|AZE62811.1\|4862941_4863349_-\|Flagellar-basal-body-rod-protein-FlgB	gnl\|CDD\|180196	PRK05680, flgB, flagellar basal body rod protein FlgB; Reviewed.	1.07773e-67
CP027755.1\|AZE62823.1\|4878188_4878425_+\|hypothetical-protein	gnl\|CDD\|379462	pfam14090, HTH_39, Helix-turn-helix domain. This helix-turn-helix domain is often found in phage proteins and is likely to be DNA-binding.	2.6612e-19
CP027755.1\|AZE62818.1\|4868181_4869570_-\|putative-MFS-type-transporter	gnl\|CDD\|341030	cd17477, MFS_YcaD_like, YcaD and similar transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MFS-type transporter YcaD, Bacillus subtilis MFS-type transporter YfkF, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.3787e-100
CP027755.1\|AZE62815.1\|4866434_4866758_+\|Negative-regulator-of-flagellin-synthesis-FlgM-(anti-sigma28)	gnl\|CDD\|274802	TIGR03824, FlgM_jcvi, flagellar biosynthesis anti-sigma factor FlgM. FlgM interacts with and inhibits the alternative sigma factor sigma(28) FliA. The C-terminus of FlgM contains the sigma(28)-binding domain.	1.06542e-20
CP027755.1\|AZE62819.1\|4875997_4877209_+\|site-specific-recombinase,-phage-integrase-family	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.42749e-38
CP027755.1\|AZE62814.1\|4865597_4866293_+\|Flagellar-basal-body-P-ring-formation-protein-FlgA	gnl\|CDD\|180794	PRK07018, flgA, flagellar basal body P-ring formation protein FlgA.	2.47966e-89
CP027755.1\|AZE62821.1\|4877866_4878070_+\|excisionase,-putative	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.45359e-10
CP027755.1\|AZE62816.1\|4866806_4867277_+\|Flagellar-biosynthesis-protein-FlgN	gnl\|CDD\|377465	pfam05130, FlgN, FlgN protein. This family includes the FlgN protein and export chaperone involved in flagellar synthesis.	7.2871e-19
CP027755.1\|AZE62817.1\|4867373_4868123_+\|Flagellar-brake-protein-YcgR	gnl\|CDD\|227868	COG5581, COG5581, c-di-GMP-binding protein [Signal transduction mechanisms].	8.66102e-44
CP027755.1\|AZE62810.1\|4862494_4862938_-\|Flagellar-basal-body-rod-protein-FlgC	gnl\|CDD\|235556	PRK05681, flgC, flagellar basal body rod protein FlgC; Reviewed.	1.27636e-69
CP027755.1\|AZE62824.1\|4878488_4878893_+\|hypothetical-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	0.00407319
CP027755.1\|AZE62813.1\|4864522_4865455_-\|Chemotaxis-protein-CheV	gnl\|CDD\|381151	cd19924, REC_CheV-like, phosphoacceptor receiver (REC) domain of chemotaxis protein CheV and similar proteins. This subfamily includes the REC domains of Bacillus subtilis chemotaxis protein CheV, Myxococcus xanthus gliding motility regulatory protein FrzE, and similar proteins. CheV is a hybrid protein with an N-terminal CheW-like domain and a C-terminal CheY-like REC domain. The CheV pathway is one of three systems employed by B. subtilis for sensory adaptation that contribute to chemotaxis. It is involved in the transmission of sensory signals from chemoreceptors to flagellar motors. Together with CheW, it is involved in the coupling of methyl-accepting chemoreceptors to the central two-component histidine kinase CheA. FrzE is a hybrid sensor histidine kinase/response regulator that is part of the Frz pathway that controls cell reversal frequency to support directional motility during swarming and fruiting body formation. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.68277e-50
CP027755.1\|AZE62809.1\|4861758_4862478_-\|Flagellar-basal-body-rod-modification-protein-FlgD	gnl\|CDD\|235847	PRK06655, flgD, flagellar hook assembly protein FlgD.	3.15674e-76

>CP027755.1|AZE62818.1|4868181_4869570_-|putative-MFS-type-transporter
MRQIWKSFRALYFASLMMLIGSGLLSTYLALRLAADNVDSLWVGALMAANYFGLVLGGKIGHRLIARVGHIRAYATCAGIVGAAVLGHGLIDWLPAWIVLRMIVGLGMMCQYMVIESWLNEQADAKQRGVVFSGYMIASYLGLVLGQLILVMHPHLGLELLMLVALCFALCLVPVAMTRRIHPAPLHPAPMEPRFFIKRVPQSLSTVLGAGLIVGSFYGLAPLYASQQGLTTEQVGLFMGSCIFAGLLVQWPLGWLSDRYDRALLIRCFALCLAITALPLAIMTEVPLEVLFVTGFFCSLVQFCLYPLAVAFSNDHVEGDRRVSLTAMLLVTYGIGASVGPLLAGIVMKLFGSQMLYAFFSLCALVLVWRIRPKAVTNLHQVDDAPLHHVAMPDSMSSSPLVAALDPRVDEQVVQEQMQGSVPDPEPEPTPEEPANEKPADEEPQEPLDPDEHPHDLSRARP
>CP027755.1|AZE62817.1|4867373_4868123_+|Flagellar-brake-protein-YcgR
MFNALNAEDAPQPPKVLTTPLEIASTLRMLQDSHDPLIITFHERSQRFQSYLVDVSRDSKTLVLDEMIPRDGERYLENGEPFRIEGFHDGVRVAWESNGTLSLSEKDGHRIYSGNMPNEVVYHQRRNAFRAALKLAQLVNIELGGEKLKAPVNGKLLDISATGCKLRFEGDISGRLQLGQVYDRFVAALPFGSMTTAVELRYLHFEDKINITFAGVRFHNMSGLVQRQVERFVYQLQREARRFDKDDDF
>CP027755.1|AZE62816.1|4866806_4867277_+|Flagellar-biosynthesis-protein-FlgN
MHHDEHLLQLIIDDLAPTQQLLELLKEESLALYGRDMPLLEEILARKQSLIVLLEQHGKKRSEILISLGLPADHDGLAQLASHSSVGDQLLSQSKELNQLLAQCQEANQLNGQSIQLQQATTANQLRILHGGEPPALYNAQGSTSRLVKPSTRSQA
>CP027755.1|AZE62815.1|4866434_4866758_+|Negative-regulator-of-flagellin-synthesis-FlgM-(anti-sigma28)
MVIDFSRLNNAPALPGNTRTGGAKDSVEAKSQPLPAKAEQASVSQSGESVHLSNEAQQLQKVTDSLRDQPVVNKARVAELKQAIADGSYKVDSNRVASKLLNFEAER
>CP027755.1|AZE62814.1|4865597_4866293_+|Flagellar-basal-body-P-ring-formation-protein-FlgA
MALLALGLNATTRADNVTLPDVLIGVTQGFLEFTVEDYLATTQTPGRYEIQVNQLDPRLRMPMCDRELTATLESPAQPIGRVTVKVRCEGASPWTVFVPAQVKLFREVVVVARPLKRTGIISFEDVALRERDISQINQGYMTSVDQAIGQRLTRPMVTDQVVTLVHLEQAEVIRKGDQVVISASSGGLNVRMPGEALSNGGMSEQIRVKNLNSNRVIKARVTAPGQVEVAL
>CP027755.1|AZE62813.1|4864522_4865455_-|Chemotaxis-protein-CheV
MAGVMDSVNQRTQLVGQNRLELLLFRLDGKQLYGINVFKVREVLQCPKLTIMPKSNPVVCGVANIRGATIPILDLALATGSSGLQDRQSPFVIITEYNTKTQGFLVRSVERIVNMNWEEIHPPPKGTGRDHYLTAVTRVDNQLVEIIDVEKILAEVAPTSEAISVGVVDAETAHKAVSLRVLTVDDSSVARKQVTRCLQTVGVDVVALNDGRQALDYLRKLVDEGKKPEEEFLMMISDIEMPEMDGYTLTAEIRNDPRMQKLHIILHTSLSGVFNQAMVKKVGADDFLAKFRPDDLASRVVDRIKAADHS
>CP027755.1|AZE62812.1|4863651_4864479_-|Chemotaxis-protein-methyltransferase-CheR
MSTGNLDFEQFRVFLEKACGILLGENKQYLVSSRLNKLMEQQGIKSLGELVQRIQGQPRSGLKEMVVDAMTTNETLWFRDTYPFEVLKNKVLPEAIKASPGQRLRIWSAACSSGQEPYSISMSIDEFERTNMGQLKAGAQIVATDLSGTMLTNCKTGEYDSLALGRGLSQERLQRYFDPKGAGRWAIKAPIKNRVEFRSFNLLDSYASLGKFDMVFCRNVLIYFSAEVKKDILLRIHGTLKRGGYLFLGASEALNGLPDHYQMVQCSPGIIYQAK
>CP027755.1|AZE62811.1|4862941_4863349_-|Flagellar-basal-body-rod-protein-FlgB
MSISFDKALGIHEQALGFRAQRAEVLANNIANADTPNYKARDLDFSAVLAAQQDKTKNGTFALNMTNSRHIEAQGLGNADESLLYRTPMQPSIDQNTVDAQLEQSNYAENSVNFQASFTLLNSKFKGLMSALRGE
>CP027755.1|AZE62810.1|4862494_4862938_-|Flagellar-basal-body-rod-protein-FlgC
MSLSSVFNIAGSGMSAQTTRLNTVASNIANAETVSSSIDQTYRARHPVFATMFQAGQSGGSDSLFQDQDAAGSGVQVLGVVEDQSNLEARYEPNHPAANEKGYVYYPNVNVVEEMADMISASRSFQTNAEMMNTAKAMMQKVLTLGQ
>CP027755.1|AZE62809.1|4861758_4862478_-|Flagellar-basal-body-rod-modification-protein-FlgD
MAIVDTSNNTAVQDLFNSKVKDASNNVSNVSKAATGNQSLGKDAFLQLLVTQLKNQNPLSPQDNGAFVAQLAQFSSLEGINTLNDSVNNISSNFSSSQALQASSLVGRSIIIQTDKAMVDTSKSMNGSVDVPSAVGNVSVKITDKDGNVVRTVDMGAQSAGSQSFIWDGKNDKGEVAPAGTYTFNASTKNDKGDAVALATSLPATVTSVTLSKTGGEMLLNLAGGMGSVKLSQIQTIGT
>CP027755.1|AZE62819.1|4875997_4877209_+|site-specific-recombinase,-phage-integrase-family
MKSKITQKLIGSLAAEAKAYRVHDTVQPGFFIRVLPSGHKSYMVTWGRNKNATLGRVGVLTLDQARTEAAQYLADAHAHGEPLAIAQGRKGSALPSLRDFIDDTYMPWFKAHHKGHEKTQHTLSNNFDPIMAQRLDAITGRDLEQIRTGWMQAGNKASTVNRKMGSISGVFSRAVEWEYINTHPLAKLKQLKVDSKGVIRYLAADETKRLRGALDARQDEMRAERESANTWRTERHREPMPSLLELPFTDHLKPMVLVSLNTGMRRGELFDLKWSAVNFDTKTITVAGATTKTSDTRHIPMNKETIGVLEAWKKQVSKSPYVFPGQGGGRFEDVKSAWLKLLERAQIDGFRWHDMRHDFASRLVMAGVPLNTVRDLLGHADVKMTLRYAHLAPGTKAAAVELI
>CP027755.1|AZE62820.1|4877205_4877838_-|hypothetical-protein
MGDDEILLLYLLYVNCNHKLIVNAWTSLDAKGRIRFKRKLIGAEEMAKNKPSQGARKTETLTLRLDPKVKMMIEMISRIRRQSITGVVEAAIEEIAFDLDAPFFYKNETNNWSLSSAITEVWSTDESERFINMCYHLPTLLTYEEQRIWETIKASKVFLATDTTVMETFWEIEGIGRIDRSSVRIWWTYLLEHVDEHKDSRTIVPFEPPF
>CP027755.1|AZE62821.1|4877866_4878070_+|excisionase,-putative
MEQAQQQMAPLSLSVEESARILGISRSATYELIAQGEIKTFKIGRRRLALASELKAFIERAAKVGAR
>CP027755.1|AZE62822.1|4878066_4878192_+|hypothetical-protein
MKYEKNKELGLRRAAREIAKAVLEHRLSENTLDSTNVKGKL
>CP027755.1|AZE62823.1|4878188_4878425_+|hypothetical-protein
MTRHSSTEQDRKMMEALRNGPVSTIEAAKDLDIVQPPNTIRRLRKKGHEIRTYWTHQSTEPGRPPHRVAKYILMREAS
>CP027755.1|AZE62824.1|4878488_4878893_+|hypothetical-protein
MARKTKYKVDFGGGRVLALPYRLLISDAFDNLSTKAVTVLMKLARNYNGRNNGDLSCTASMMAKGKPMDAKTLASALAELMDAGLIIRTRENRKGGREQGMARCALYAITWAAIDDCPGKDLEIGPGPPRFKFV
>CP027755.1|AZE62825.1|4879361_4879826_-|hypothetical-protein
MSRSYKAIAETAISDLYEAQAALDNMHAIFTLMLQHFPEDSTGNAFAQLGTLESNDWSTKIYQWCGCMENEMDDANEVAARAISVERKHATRWWTHLNEMRRRKELPEWVAAGIGTHDEHDQMLGSRKAVNQALFGSDDLGGDQHYRPIPLDQA
>CP027755.1|AZE62826.1|4879822_4880086_-|hypothetical-protein
MNAQARTIQEVAHDALEDLESAQIALRKVEAVLYAALADKGTSQHVRNLVDVAWNLAADGANTADCNREEITAALAGCAALGAGGDL
>CP027755.1|AZE62827.1|4880082_4880361_-|hypothetical-protein
MVQIWAISEEVPSRCVNSGLAITRRNFEVDVMQFKQNTIQILDSRGQIIATMALPANIKLTELAPLKILGDISFKVLSGAAPSRGICLGGVV
>CP027755.1|AZE62828.1|4880389_4880620_-|hypothetical-protein
MEDSNSATGKRTGADRQRDFAERQKAAGYKRTTVWIHEETAKEGIRAARAGKPLEPMESKDPLSWAAGWISEKGKQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP027755_2	2.1\|2893124\|39\|CP027755\|CRISPRCasFinder	2893124-2893162	39	CP027755.1	3512955-3512993	1	0.974

1. spacer 2.1|2893124|39|CP027755|CRISPRCasFinder matches to position: 3512955-3512993, mismatch: 1, identity: 0.974

tatttgactgatggtctcggtccagatgtgggagggggc	CRISPR spacer
tatttgactgatggtctcggtccaaatgtgggagggggc	Protospacer
************************.**************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

364563 : 397850

Pseudomonas_phage(68.97%)

tail,capsid,terminase,head

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZE58713.1\|364563_365898_-	Integrase	B7SYF8	Stenotrophomonas_phage	4.6e-67	37.9
AZE58714.1\|366263_366488_-	hypothetical protein	NA	NA	NA	NA
AZE58715.1\|366507_367656_-	Mobile element protein	V9IQN0	Stenotrophomonas_phage	4.1e-72	40.5
AZE58716.1\|367652_367865_-	hypothetical protein	NA	NA	NA	NA
AZE58717.1\|367957_368206_-	hypothetical protein	NA	NA	NA	NA
AZE58718.1\|368335_371047_-	Phage protein	A0A2H4J936	uncultured_Caudovirales_phage	3.4e-287	54.3
AZE58719.1\|371046_371280_-	Adenylate kinase	NA	NA	NA	NA
AZE58720.1\|371355_371718_-	hypothetical protein	NA	NA	NA	NA
AZE58721.1\|371714_372224_-	Phage protein	A0A2H4JG61	uncultured_Caudovirales_phage	9.6e-42	54.3
AZE58722.1\|372223_372436_-	hypothetical protein	A0A2H4JE67	uncultured_Caudovirales_phage	1.8e-10	55.2
AZE58723.1\|372520_372871_+	Transcriptional regulator, Cro/CI family	NA	NA	NA	NA
AZE58724.1\|372946_373132_+	hypothetical protein	NA	NA	NA	NA
AZE58725.1\|373170_373428_-	putative phage protein	A5X9H0	Aeromonas_virus	7.8e-16	49.4
AZE58726.1\|373502_374249_-\|capsid	Phage-related capsid packaging protein	A0A0U4B0L9	Pseudomonas_phage	2.7e-101	76.6
AZE58727.1\|374283_376335_-\|terminase	Phage terminase, ATPase subunit	A0A0U4JIZ9	Pseudomonas_phage	9.3e-261	71.8
AZE58728.1\|376496_377417_+\|capsid	Phage capsid scaffolding protein	A0A0U4JVV6	Pseudomonas_phage	6.6e-65	48.1
AZE58729.1\|377418_378441_+\|capsid	Phage capsid protein	A0A0U4K5I9	Pseudomonas_phage	2.0e-123	68.2
AZE58730.1\|378437_379166_+\|terminase	putative terminase, endonuclease subunit	A0A0U4JEJ1	Pseudomonas_phage	5.4e-70	61.4
AZE58731.1\|379263_379734_+\|head	putative head completion/stabilization protein	A0A0U4J933	Pseudomonas_phage	2.8e-35	55.5
AZE58732.1\|379730_380180_+	hypothetical protein	A0A0U4IBS7	Pseudomonas_phage	1.1e-44	61.8
AZE58733.1\|380205_380850_+	hypothetical protein	A0A0U4ISN1	Pseudomonas_phage	5.3e-61	60.6
AZE58734.1\|380861_381983_+	Phage protein	A0A0U4KLE6	Pseudomonas_phage	1.8e-141	68.6
AZE58735.1\|381988_382438_+	hypothetical protein	A0A0U3TH58	Pseudomonas_phage	2.4e-60	75.7
AZE58736.1\|382437_382656_+	putative Zinc-finger containing protein	A0A0U4IIN4	Pseudomonas_phage	5.8e-12	56.9
AZE58737.1\|382652_382859_+	hypothetical protein	NA	NA	NA	NA
AZE58738.1\|382855_383389_+	putative phage lysozyme	NA	NA	NA	NA
AZE58739.1\|383388_383868_+	Endopeptidase	A0A0U4JXC2	Pseudomonas_phage	7.7e-25	50.6
AZE58740.1\|383881_384169_+	hypothetical protein	A0A0U4B0P2	Pseudomonas_phage	9.0e-29	68.4
AZE58741.1\|384339_386652_+\|tail	Phage-related tail protein	A0A0U4IJ81	Pseudomonas_phage	5.9e-147	41.7
AZE58742.1\|386648_386966_+	hypothetical protein	A0A0U4B0N5	Pseudomonas_phage	1.0e-33	76.5
AZE58743.1\|386962_388135_+	Phage protein	A0A0U4JJ14	Pseudomonas_phage	2.1e-164	74.0
AZE58744.1\|388131_388656_+	hypothetical protein	A0A0U4JVX3	Pseudomonas_phage	2.6e-82	81.0
AZE58745.1\|388665_391245_+\|tail	Phage tail fiber protein	A0A0U4K5K2	Pseudomonas_phage	5.1e-107	63.5
AZE58746.1\|391248_391887_+	hypothetical protein	NA	NA	NA	NA
AZE58747.1\|391939_392812_+	hypothetical protein	NA	NA	NA	NA
AZE58748.1\|392808_393360_+	hypothetical protein	A0A0U4J942	Pseudomonas_phage	4.1e-54	63.0
AZE58749.1\|393356_394061_+	hypothetical protein	A0A1D9CA29	Salinivibrio_phage	3.3e-40	38.3
AZE58750.1\|394033_395005_+	hypothetical protein	A0A0U4IBV2	Pseudomonas_phage	4.0e-121	66.6
AZE58751.1\|395266_397069_-	hypothetical protein	A0A2I7RXX1	Vibrio_phage	8.5e-08	23.4
AZE58752.1\|397171_397402_+	hypothetical protein	NA	NA	NA	NA
AZE58753.1\|397634_397850_-	hypothetical protein	A0A2H4J177	uncultured_Caudovirales_phage	2.3e-21	77.6

DBSCAN-SWA_2

1374852 : 1460280

Pseudomonas_phage(33.33%)

plate,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZE59596.1\|1374852_1375323_+\|tRNA	Cys-tRNA(Pro) deacylase YbaK	NA	NA	NA	NA
AZE59597.1\|1375383_1376439_-	Ferric iron ABC transporter, ATP-binding protein	G9BWD6	Planktothrix_phage	5.5e-23	30.9
AZE59598.1\|1376435_1377359_-	Ornithine carbamoyltransferase	A0A1J0F9B8	Only_Syngen_Nebraska_virus	1.9e-19	27.7
AZE59599.1\|1377792_1379901_+	Formate dehydrogenase-O, major subunit	NA	NA	NA	NA
AZE59600.1\|1379987_1380326_+	Glutaredoxin-related protein	NA	NA	NA	NA
AZE59601.1\|1380388_1380859_-	Bacterioferritin	NA	NA	NA	NA
AZE59602.1\|1381059_1381278_-	Bacterioferritin-associated ferredoxin	NA	NA	NA	NA
AZE59603.1\|1381343_1381463_-	hypothetical protein	NA	NA	NA	NA
AZE59604.1\|1381521_1382124_+	Alkyl hydroperoxide reductase subunit C-like protein	NA	NA	NA	NA
AZE59605.1\|1382191_1382863_-	Ribonuclease T	NA	NA	NA	NA
AZE59606.1\|1382859_1383906_-	Dihydroorotase	NA	NA	NA	NA
AZE59607.1\|1384062_1384971_+	outer membrane protein, OmpA family	NA	NA	NA	NA
AZE59608.1\|1385100_1386318_+	Argininosuccinate synthase	NA	NA	NA	NA
AZE59609.1\|1386626_1386767_+	hypothetical protein	NA	NA	NA	NA
AZE59610.1\|1386944_1387577_+	Two-component transcriptional response regulator, LuxR family	NA	NA	NA	NA
AZE59611.1\|1387660_1387843_-	hypothetical protein	NA	NA	NA	NA
AZE59612.1\|1387950_1388589_-	Endonuclease III	NA	NA	NA	NA
AZE59613.1\|1388697_1389867_-	Electron transport complex protein RnfB	NA	NA	NA	NA
AZE59614.1\|1389954_1392006_-\|tRNA	Methionyl-tRNA synthetase	NA	NA	NA	NA
AZE59615.1\|1392178_1393273_+	[4Fe-4S] cluster assembly scaffold protein Mrp (ApbC)	NA	NA	NA	NA
AZE59616.1\|1393316_1393469_-	hypothetical protein	NA	NA	NA	NA
AZE59617.1\|1393934_1394258_-	4Fe-4S dicluster domain	NA	NA	NA	NA
AZE59618.1\|1394400_1397049_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	8.9e-30	21.9
AZE59619.1\|1397205_1397319_-	hypothetical protein	NA	NA	NA	NA
AZE59620.1\|1397504_1397828_-	4Fe-4S dicluster domain	NA	NA	NA	NA
AZE59621.1\|1398019_1398181_+	hypothetical protein	A0A2H4JA19	uncultured_Caudovirales_phage	8.3e-08	61.2
AZE59622.1\|1398621_1399299_-	hypothetical protein	NA	NA	NA	NA
AZE59623.1\|1399383_1399755_-	hypothetical protein	NA	NA	NA	NA
AZE59624.1\|1399747_1400236_-	GepA protein	D0UIM3	Aggregatibacter_phage	1.3e-27	44.5
AZE59625.1\|1400479_1401214_+	Transcriptional regulator	B5TK58	Pseudomonas_phage	1.7e-119	88.1
AZE59626.1\|1401416_1401521_+	hypothetical protein	NA	NA	NA	NA
AZE59627.1\|1401804_1402143_+	Holin	B5TK61	Pseudomonas_phage	1.4e-44	85.4
AZE59628.1\|1402166_1402682_+	hypothetical protein	NA	NA	NA	NA
AZE59629.1\|1402685_1403297_+\|plate	Baseplate assembly protein V	A0A2H4JBW8	uncultured_Caudovirales_phage	1.0e-45	52.2
AZE59630.1\|1403306_1403639_+\|plate	Baseplate assembly protein W	A0A2H4JI46	uncultured_Caudovirales_phage	9.7e-35	65.5
AZE59631.1\|1403635_1404631_+\|plate	Phage-related baseplate assembly protein	A0A2H4JC04	uncultured_Caudovirales_phage	1.2e-112	63.8
AZE59632.1\|1404627_1405266_+	Tail protein I	A0A2H4JDK0	uncultured_Caudovirales_phage	4.8e-38	51.9
AZE59633.1\|1405262_1405793_+\|tail	Phage tail fiber protein	B0ZSG1	Halomonas_phage	5.0e-49	58.1
AZE59634.1\|1405840_1406623_+	hypothetical protein	NA	NA	NA	NA
AZE59635.1\|1406625_1406928_+	Phage protein	Q8H9M8	Vibrio_phage	2.1e-12	47.4
AZE59636.1\|1407015_1407189_+	hypothetical protein	NA	NA	NA	NA
AZE59637.1\|1407191_1408358_+\|tail	Major tail sheath protein	B0ZSG8	Halomonas_phage	3.2e-125	57.2
AZE59638.1\|1408357_1408864_+	hypothetical protein	Q6R4W3	Vibrio_virus	2.2e-22	34.5
AZE59639.1\|1408915_1409488_+	hypothetical protein	B0ZSH0	Halomonas_phage	1.2e-29	40.1
AZE59640.1\|1409496_1409610_+	hypothetical protein	NA	NA	NA	NA
AZE59641.1\|1409615_1411457_+\|tail	Phage tail length tape-measure protein	NA	NA	NA	NA
AZE59642.1\|1411456_1411840_+	Phage protein	B0ZSH2	Halomonas_phage	1.3e-35	59.1
AZE59643.1\|1411832_1412045_+\|tail	P2-like prophage tail protein X	A0A2H4JGD9	uncultured_Caudovirales_phage	2.4e-18	62.9
AZE59644.1\|1412054_1413065_+\|tail	Phage tail protein D	A0A2H4JH05	uncultured_Caudovirales_phage	2.6e-99	54.5
AZE59645.1\|1413130_1413328_+	hypothetical protein	NA	NA	NA	NA
AZE59646.1\|1413420_1413912_+	Acyl-CoA dehydrogenase	H2BDC0	Pseudomonas_virus	3.0e-48	61.6
AZE59647.1\|1413920_1414271_+	hypothetical protein	NA	NA	NA	NA
AZE59648.1\|1414312_1414555_+	Phage protein	A0A0U4J8S9	Pseudomonas_phage	9.0e-14	50.0
AZE59649.1\|1414617_1415778_+	phage protein	A0A0S2SYD9	Pseudomonas_phage	3.3e-21	29.5
AZE59650.1\|1415806_1416145_+\|tail	Phage minor tail protein	A0A0S2SYI2	Pseudomonas_phage	6.6e-31	51.8
AZE59651.1\|1416226_1417057_+\|tail	Phage minor tail protein	A0A2I6PIA7	Pseudomonas_phage	3.4e-84	64.3
AZE59652.1\|1417059_1417833_+\|tail	Phage tail assembly protein	A0A2I6PI52	Pseudomonas_phage	4.5e-83	53.7
AZE59653.1\|1417866_1418499_+\|tail	Phage tail assembly protein I	A0A2I6PI69	Pseudomonas_phage	1.7e-48	49.0
AZE59654.1\|1418531_1419140_+\|tail	Phage tail assembly protein I	F1C572	Cronobacter_phage	3.2e-44	50.8
AZE59655.1\|1419199_1423138_+\|tail	Phage tail fiber protein	A4JX16	Burkholderia_virus	3.5e-280	45.1
AZE59656.1\|1423460_1424156_+	hypothetical protein	NA	NA	NA	NA
AZE59657.1\|1424241_1425273_+	phage protein	H9D1F9	Salinivibrio_phage	5.9e-06	31.0
AZE59658.1\|1425275_1425602_+	hypothetical protein	NA	NA	NA	NA
AZE59659.1\|1425669_1426749_+	phage protein	A0A1B0VMK1	Pseudomonas_phage	1.4e-05	53.8
AZE59660.1\|1426745_1427093_+	hypothetical protein	A0A2D1GNF5	Pseudomonas_phage	6.4e-13	41.6
AZE59661.1\|1427089_1427302_+	hypothetical protein	NA	NA	NA	NA
AZE59662.1\|1427338_1427878_+	Phage endolysin	A0A059VA40	Pseudomonas_phage	1.6e-66	69.9
AZE59663.1\|1427865_1428360_+	hypothetical protein	B5TK84	Pseudomonas_phage	3.1e-37	55.7
AZE59664.1\|1428441_1428942_+	Nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	9.1e-69	80.1
AZE59665.1\|1429025_1430084_+	RecA protein	A0A0S2MVG1	Bacillus_phage	2.4e-111	62.4
AZE59666.1\|1430092_1430560_+	Regulatory protein RecX	NA	NA	NA	NA
AZE59667.1\|1430619_1431732_-	Decarboxylase family protein	NA	NA	NA	NA
AZE59668.1\|1432023_1432458_-	Putative NADPH-quinone reductase (modulator of drug activity B)	NA	NA	NA	NA
AZE59669.1\|1432592_1433357_+	putative conserved protein YfiP, contains DTW domain	NA	NA	NA	NA
AZE59670.1\|1433609_1434260_+	Transcriptional regulator, LuxR family	NA	NA	NA	NA
AZE59671.1\|1434336_1434699_+	Diacylglycerol kinase	NA	NA	NA	NA
AZE59672.1\|1434702_1435689_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZE59673.1\|1435754_1436534_+	Ferredoxin--NADP(+) reductase	NA	NA	NA	NA
AZE59674.1\|1436716_1437412_-	S-adenosylmethionine-dependent methyltransferase YaeB	NA	NA	NA	NA
AZE59675.1\|1437415_1437877_-	Uncharacterized protein YehS	Q9EYF4	Enterobacteria_phage	2.0e-38	52.0
AZE59676.1\|1437945_1438656_-	Ribosomal large subunit pseudouridine synthase F	NA	NA	NA	NA
AZE59677.1\|1438727_1439201_-	Acetyltransferase	NA	NA	NA	NA
AZE59678.1\|1439387_1440728_-	Ribosomal protein S12p Asp88 methylthiotransferase	NA	NA	NA	NA
AZE59679.1\|1441017_1442919_+	Kup system potassium uptake protein	M1HZV6	Acanthocystis_turfacea_Chlorella_virus	8.5e-75	33.2
AZE59680.1\|1443131_1444238_+	NADH-dependent flavin oxidoreductase	NA	NA	NA	NA
AZE59681.1\|1444341_1444878_+	hypothetical protein	NA	NA	NA	NA
AZE59682.1\|1445082_1445268_+	hypothetical protein	NA	NA	NA	NA
AZE59683.1\|1445321_1446947_-	Glucans biosynthesis protein D precursor	NA	NA	NA	NA
AZE59684.1\|1447251_1447959_+	putative membrane protein	NA	NA	NA	NA
AZE59685.1\|1448416_1450039_+	Methyl-accepting chemotaxis protein	NA	NA	NA	NA
AZE59686.1\|1450038_1450551_+	Chemotaxis signal transduction protein	NA	NA	NA	NA
AZE59687.1\|1450547_1451807_+	Chemotaxis protein methyltransferase CheR	NA	NA	NA	NA
AZE59688.1\|1451803_1452505_+	Chemotaxis signal transduction protein	NA	NA	NA	NA
AZE59689.1\|1452501_1454769_+	Sensor histidine kinase/response regulator	Q56AR1	Bacillus_thuringiensis_phage	7.4e-09	27.4
AZE59690.1\|1454765_1455776_+	Chemotaxis response regulator protein-glutamate methylesterase	Q6XM27	Feldmannia_irregularis_virus	9.9e-06	40.3
AZE59691.1\|1455828_1456830_+	Two-component transcriptional response regulator, LuxR family	A0A127AWB9	Bacillus_phage	5.6e-17	35.8
AZE59692.1\|1457851_1458694_+	Peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	1.5e-07	46.6
AZE59693.1\|1458777_1460280_+\|tRNA	Lysyl-tRNA synthetase (class II)	A0A2K9KZX5	Tupanvirus	6.1e-84	39.2

DBSCAN-SWA_3

1536971 : 1541933

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZE59765.1\|1536971_1537721_+	5'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.9e-63	49.8
AZE59766.1\|1537720_1538398_+	Protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	3.1e-43	53.1
AZE59767.1\|1538607_1539444_+	Murein hydrolase activator NlpD	A0A0S2SXL7	Bacillus_phage	8.2e-06	33.3
AZE59768.1\|1539549_1540557_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	1.3e-34	36.2
AZE59769.1\|1540769_1540979_-	Cold shock protein of CSP family	Q9AZD3	Lactococcus_phage	2.2e-16	66.7
AZE59770.1\|1541366_1541933_+	Deoxycytidine triphosphate deaminase	S5VM63	Pseudomonas_phage	3.7e-74	73.3

DBSCAN-SWA_4

3746025 : 3811293

uncultured_Caudovirales_phage(67.39%)

plate,tRNA,portal,integrase,protease,terminase,tail

attL 3769850:3769865|attR 3784922:3784937

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZE61734.1\|3746025_3746238_+	hypothetical protein	A0A2H4J177	uncultured_Caudovirales_phage	8.7e-21	78.8
AZE61735.1\|3746699_3747182_+	hypothetical protein	NA	NA	NA	NA
AZE61736.1\|3747371_3748010_-	hypothetical protein	NA	NA	NA	NA
AZE61737.1\|3748066_3748861_-	Dam modification methylase	C7BGE1	Burkholderia_phage	1.9e-100	65.8
AZE61738.1\|3749010_3749553_-	hypothetical protein	B5TK84	Pseudomonas_phage	2.7e-42	54.6
AZE61739.1\|3749534_3750098_-	Lytic enzyme	B5TK83	Pseudomonas_phage	4.3e-83	79.7
AZE61740.1\|3750145_3751234_-	Phage protein D	A0A2H4JBF6	uncultured_Caudovirales_phage	1.2e-150	77.3
AZE61741.1\|3751244_3751568_-	hypothetical protein	NA	NA	NA	NA
AZE61742.1\|3751635_3751809_-\|tail	Phage tail protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	2.1e-12	60.7
AZE61743.1\|3751816_3752662_-	Phage protein U	A0A2H4J875	uncultured_Caudovirales_phage	1.4e-114	72.9
AZE61744.1\|3752671_3755740_-\|tail	Phage tail length tape-measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	1.7e-229	69.7
AZE61745.1\|3755890_3756199_-	hypothetical protein	A0A2H4J873	uncultured_Caudovirales_phage	2.4e-19	51.0
AZE61746.1\|3756211_3756715_-\|tail	Phage major tail tube protein	Q7M2A5	Pseudomonas_phage	1.9e-66	73.0
AZE61747.1\|3756727_3757900_-\|tail	Phage tail sheath monomer	A0A2H4J869	uncultured_Caudovirales_phage	4.4e-191	83.8
AZE61748.1\|3757981_3758371_-	hypothetical protein	NA	NA	NA	NA
AZE61749.1\|3758379_3760263_-\|tail	Phage tail fiber protein	A4PE45	Ralstonia_virus	3.7e-70	51.1
AZE61750.1\|3760259_3760949_-\|tail	Phage tail fiber	A0A2H4JDH5	uncultured_Caudovirales_phage	2.8e-76	75.4
AZE61751.1\|3760945_3761833_-\|plate	Baseplate assembly protein J	A0A2H4JFK9	uncultured_Caudovirales_phage	3.4e-127	78.8
AZE61752.1\|3761829_3762156_-\|plate	Phage baseplate assembly protein	A0A2H4JA09	uncultured_Caudovirales_phage	1.2e-34	65.7
AZE61753.1\|3762161_3762407_-	hypothetical protein	A0A2H4J885	uncultured_Caudovirales_phage	1.8e-06	42.9
AZE61754.1\|3762465_3763029_-\|plate	Phage baseplate assembly protein	A0A2H4JG06	uncultured_Caudovirales_phage	7.1e-54	71.8
AZE61755.1\|3763025_3763556_-	hypothetical protein	A0A2H4J881	uncultured_Caudovirales_phage	6.5e-65	67.6
AZE61756.1\|3763548_3764205_-	hypothetical protein	A0A2H4JBV1	uncultured_Caudovirales_phage	4.8e-78	66.5
AZE61757.1\|3764201_3764522_-	hypothetical protein	A0A2H4J879	uncultured_Caudovirales_phage	2.2e-39	72.4
AZE61758.1\|3764524_3765520_-	Phage protein	A0A2H4J890	uncultured_Caudovirales_phage	6.3e-170	88.2
AZE61759.1\|3765582_3765921_-	hypothetical protein	A0A2H4JF15	uncultured_Caudovirales_phage	5.2e-44	84.4
AZE61760.1\|3765917_3767060_-\|protease	Prophage Clp protease-like protein	A0A2H4JDI2	uncultured_Caudovirales_phage	1.9e-138	68.5
AZE61761.1\|3767056_3768538_-\|portal	phage portal protein, lambda family	A0A2H4JFL5	uncultured_Caudovirales_phage	6.1e-246	85.4
AZE61762.1\|3768537_3768744_-	hypothetical protein	A0A2H4JA19	uncultured_Caudovirales_phage	3.4e-22	76.5
AZE61763.1\|3768825_3769266_+	hypothetical protein	S4TUD6	Salmonella_phage	1.7e-10	28.4
AZE61764.1\|3769267_3771265_-\|terminase	terminase, large subunit, putative	A0A2H4J898	uncultured_Caudovirales_phage	0.0e+00	84.7
3769850:3769865	attL	NA	NA	NA	NA
AZE61765.1\|3771268_3771874_-	hypothetical protein	A0A2H4JG15	uncultured_Caudovirales_phage	7.6e-62	68.2
AZE61766.1\|3772080_3772425_-	Holin	A0A2H4J893	uncultured_Caudovirales_phage	2.2e-45	79.6
AZE61767.1\|3772951_3773317_-	hypothetical protein	NA	NA	NA	NA
AZE61768.1\|3773309_3775526_-	DNA primase, phage associated	A0A2D1GN57	Marinobacter_phage	1.5e-192	47.9
AZE61769.1\|3775735_3776254_-	hypothetical protein	NA	NA	NA	NA
AZE61770.1\|3776583_3776814_-	hypothetical protein	NA	NA	NA	NA
AZE61771.1\|3776913_3777561_+	SOS-response transcriptional repressor	A0A0M3LSL8	Mannheimia_phage	2.2e-14	40.5
AZE61772.1\|3777579_3777909_-	hypothetical protein	NA	NA	NA	NA
AZE61773.1\|3778456_3778633_+	hypothetical protein	NA	NA	NA	NA
AZE61774.1\|3778629_3779211_+	hypothetical protein	NA	NA	NA	NA
AZE61775.1\|3779220_3779505_+	DNA-binding protein Roi-related protein	NA	NA	NA	NA
AZE61776.1\|3779660_3779987_+	transcriptional regulator, putative	NA	NA	NA	NA
AZE61777.1\|3780034_3780433_+	hypothetical protein	NA	NA	NA	NA
AZE61778.1\|3780429_3780972_+	putative hydrolase, HD superfamily	A0A2D1GNL9	Pseudomonas_phage	1.4e-27	43.6
AZE61779.1\|3780968_3781466_+	hypothetical protein	A0A2H4JF29	uncultured_Caudovirales_phage	5.2e-08	39.2
AZE61780.1\|3781467_3782517_+\|integrase	Phage integrase	A0A2H4JDJ8	uncultured_Caudovirales_phage	7.9e-107	56.1
AZE61781.1\|3782876_3783548_+	Putative TEGT family carrier/transport protein	A0A2H4JFM9	uncultured_Caudovirales_phage	3.9e-107	93.3
AZE61782.1\|3783621_3784641_-	UDP-N-acetylenolpyruvoylglucosamine reductase	NA	NA	NA	NA
AZE61783.1\|3784637_3785102_-	Low molecular weight protein tyrosine phosphatase	NA	NA	NA	NA
3784922:3784937	attR	NA	NA	NA	NA
AZE61784.1\|3785101_3785866_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
AZE61785.1\|3785862_3786048_-	Protein YcaR in KDO2-Lipid A biosynthesis cluster	NA	NA	NA	NA
AZE61786.1\|3786072_3787083_-	Tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
AZE61787.1\|3787082_3787511_-	Biopolymer transport protein ExbD/TolR	NA	NA	NA	NA
AZE61788.1\|3787507_3788143_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
AZE61789.1\|3788252_3790478_-	DNA internalization-related competence protein ComEC/Rec2	Q332C0	Clostridium_botulinum_C_phage	2.7e-19	27.7
AZE61790.1\|3790613_3791129_+	hypothetical protein	NA	NA	NA	NA
AZE61791.1\|3791133_3792495_-	Signal transduction histidine kinase	NA	NA	NA	NA
AZE61792.1\|3792478_3793207_-	Two-component transcriptional response regulator, LuxR family	W8CYM9	Bacillus_phage	4.8e-26	30.0
AZE61793.1\|3793412_3796166_+	Signal transduction histidine-protein kinase BarA	A0A1V0SGX0	Hokovirus	2.1e-45	28.0
AZE61794.1\|3796188_3796341_-	hypothetical protein	NA	NA	NA	NA
AZE61795.1\|3796373_3797363_+	D-lactate dehydrogenase	M1I4S0	Paramecium_bursaria_Chlorella_virus	4.4e-67	41.3
AZE61796.1\|3797434_3797875_+	hypothetical protein	NA	NA	NA	NA
AZE61797.1\|3797871_3798276_+	Heat shock protein	NA	NA	NA	NA
AZE61798.1\|3798417_3798879_-	Thioredoxin	NA	NA	NA	NA
AZE61799.1\|3798994_3799348_+	Uncharacterized protein YfgD	NA	NA	NA	NA
AZE61800.1\|3799344_3799959_+	Flavoprotein WrbA	NA	NA	NA	NA
AZE61801.1\|3799942_3800353_+	hypothetical protein	NA	NA	NA	NA
AZE61802.1\|3800499_3801171_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
AZE61803.1\|3801238_3802063_-\|tRNA	tRNA(Cytosine32)-2-thiocytidine synthetase	A0A0U2S5Z2	Escherichia_phage	6.9e-106	72.0
AZE61804.1\|3802414_3803017_+	Inner membrane protein YohC	NA	NA	NA	NA
AZE61805.1\|3803146_3803641_+	Protein SprT	NA	NA	NA	NA
AZE61806.1\|3803735_3804911_-	Alpha-methylacyl-CoA racemase	NA	NA	NA	NA
AZE61807.1\|3805068_3805461_+\|tRNA	tRNA 5-methylaminomethyl-2-thiouridine synthase subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	5.7e-58	85.4
AZE61808.1\|3805462_3805813_+\|tRNA	tRNA 5-methylaminomethyl-2-thiouridine synthase subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	1.6e-40	69.2
AZE61809.1\|3805812_3806091_+\|tRNA	tRNA 5-methylaminomethyl-2-thiouridine synthase subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	1.5e-25	60.6
AZE61810.1\|3806087_3806423_+\|tRNA	tRNA 2-thiouridine synthesis protein TusE	A0A2H4J8B6	uncultured_Caudovirales_phage	2.1e-45	78.4
AZE61811.1\|3806419_3807421_+	Anthranilate phosphoribosyltransferase like	A0A2H4JBY5	uncultured_Caudovirales_phage	1.2e-168	86.0
AZE61812.1\|3807507_3808503_+	Glutathione S-transferase, omega	NA	NA	NA	NA
AZE61813.1\|3808617_3810012_-	Precorrin-2 oxidase	NA	NA	NA	NA
AZE61814.1\|3810012_3811293_-\|tRNA	Seryl-tRNA synthetase	A0A1B1IVT2	uncultured_Mediterranean_phage	6.3e-98	53.6

DBSCAN-SWA_5

4464406 : 4467476

Pseudomonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZE62419.1\|4464406_4464661_+	hypothetical protein	B5TK57	Pseudomonas_phage	2.1e-13	60.0
AZE62420.1\|4464816_4465329_-	Cold shock protein of CSP family	A0A218MMZ6	uncultured_virus	3.2e-08	40.6
AZE62421.1\|4465365_4465566_-	Cold shock protein of CSP family	Q9AZD3	Lactococcus_phage	1.8e-07	43.8
AZE62422.1\|4466082_4466337_+	hypothetical protein	B5TK57	Pseudomonas_phage	4.7e-13	58.7
AZE62423.1\|4466495_4466705_-	Cold shock protein of CSP family	A0A2H4N7Y6	Lake_Baikal_phage	7.5e-09	51.8
AZE62424.1\|4467038_4467476_-	Cold shock protein of CSP family	A0A2H4N7Y6	Lake_Baikal_phage	1.4e-17	62.7

DBSCAN-SWA_6

5293443 : 5300471

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZE63212.1\|5293443_5294460_+	diguanylate cyclase/phosphodiesterase	A0A127AWB9	Bacillus_phage	6.5e-13	33.9
AZE63213.1\|5294574_5295828_+	Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase	A0A1V0SKB7	Klosneuvirus	1.5e-19	27.5
AZE63214.1\|5295994_5296711_+	hypothetical protein	NA	NA	NA	NA
AZE63215.1\|5296890_5297982_-	Periplasmic aromatic amino acid aminotransferase beta precursor	A0A1X6WGT4	Pacmanvirus	4.5e-12	24.1
AZE63216.1\|5298195_5298801_+	Helix-turn-helix domain protein	A0A2H4J122	uncultured_Caudovirales_phage	4.5e-54	58.6
AZE63217.1\|5298787_5299657_+	Putative preQ0 transporter YhhQ	A0A2H4J2N7	uncultured_Caudovirales_phage	4.7e-105	68.1
AZE63218.1\|5299772_5300471_-	7-cyano-7-deazaguanine synthase	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.6e-95	73.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP027755

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection