CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	0 crisprs	csa3,WYL	2
CP034150	Pantoea agglomerans strain L15 plasmid pPagL15_2, complete sequence	0 crisprs	NA	0
CP034151	Pantoea agglomerans strain L15 plasmid pPagL15_3, complete sequence	0 crisprs	NA	3
CP034148	Pantoea agglomerans strain L15 chromosome, complete genome	2 crisprs	DEDDh,cas3,DinG,csa3	3

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

467382 : 480533

Enterobacteria_phage(20.0%)

terminase,holin,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI53392.1\|467382_468462_+	acyltransferase	A0A2H4JA46	uncultured_Caudovirales_phage	1.7e-27	34.3
AZI53393.1\|468505_468940_-\|tail	phage tail protein	Q8W612	Enterobacteria_phage	5.9e-08	40.3
AZI53394.1\|468944_470276_-	hypothetical protein	Q7Y5S2	Haemophilus_phage	4.8e-16	45.6
AZI53395.1\|470280_470856_-	DUF2612 domain-containing protein	D0UIH4	Aggregatibacter_phage	5.6e-30	37.9
AZI53396.1\|472180_473488_-\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	9.1e-153	59.6
AZI53397.1\|473465_474473_-\|terminase	terminase small subunit	Q5QF76	Pseudomonas_virus	1.4e-36	44.0
AZI53398.1\|474628_475075_+	arginine repressor	NA	NA	NA	NA
AZI53399.1\|475408_476026_-	hypothetical protein	H2BDB7	Pseudomonas_virus	6.4e-48	46.4
AZI53531.1\|476009_476840_-	hypothetical protein	B5WZS7	Pseudomonas_phage	2.1e-62	45.4
AZI53400.1\|476869_477406_-	hypothetical protein	B5WZS6	Pseudomonas_phage	2.2e-36	43.3
AZI53532.1\|477443_477638_-	hypothetical protein	Q76H62	Enterobacteria_phage	5.0e-07	57.6
AZI53401.1\|477887_478307_-	structural protein	A0A0E3GMJ2	Enterobacteria_phage	6.7e-41	55.4
AZI53402.1\|478293_478584_-\|holin	phage holin family protein	A0A0F6TJP7	Escherichia_coli_O157_typing_phage	5.0e-11	42.4
AZI53403.1\|478583_478952_-	hypothetical protein	A0A1S5NRL1	Burkholderia_phage	3.2e-10	41.4
AZI53404.1\|479175_479481_+	hypothetical protein	NA	NA	NA	NA
AZI53405.1\|479891_480074_+	addiction module toxin, HicA family	A0A0D4DC32	Acinetobacter_phage	3.7e-12	55.9
AZI53406.1\|480119_480533_+	type II toxin-antitoxin system HicB family antitoxin	A0A0D4DCG1	Acinetobacter_phage	4.9e-20	39.7

DBSCAN-SWA_2

483942 : 490353

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI53409.1\|483942_484986_-	DNA cytosine methyltransferase	A0A0R6PG08	Moraxella_phage	5.6e-52	38.3
AZI53410.1\|485218_485776_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	8.0e-58	59.8
AZI53533.1\|485772_486066_-	hypothetical protein	Q6V7S4	Burkholderia_virus	7.8e-20	52.7
AZI53411.1\|486062_486443_-	hypothetical protein	NA	NA	NA	NA
AZI53534.1\|486439_487033_-	DUF1367 family protein	H9C173	Pectobacterium_phage	2.0e-46	46.2
AZI53412.1\|487072_487288_-	hypothetical protein	NA	NA	NA	NA
AZI53413.1\|487620_487938_+	XRE family transcriptional regulator	NA	NA	NA	NA
AZI53414.1\|487992_488457_-	hypothetical protein	NA	NA	NA	NA
AZI53415.1\|488473_488887_-	hypothetical protein	NA	NA	NA	NA
AZI53416.1\|488846_489425_-	replication protein	A0A0U2JGJ0	Escherichia_phage	2.2e-42	54.0
AZI53417.1\|489312_490353_-	DNA-binding protein	Q286X4	Escherichia_phage	4.9e-16	30.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP034151

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 5549

Enterobacteria_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI53687.1\|1358_2345_-	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	9.2e-89	56.6
AZI53688.1\|2341_3550_-	ParA family protein	Q1MVJ3	Enterobacteria_phage	5.1e-174	75.2
AZI53689.1\|4682_5549_-	RepB family plasmid replication initiator protein	Q71TL8	Escherichia_phage	2.2e-118	73.0

DBSCAN-SWA_2

19100 : 29108

Vibrio_phage(25.0%)

integrase

attL 15682:15697|attR 45633:45648

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
15682:15697	attL	NA	NA	NA	NA
AZI53699.1\|19100_19895_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.4e-47	84.8
AZI53700.1\|20213_20837_+	chromosome partitioning protein ParA	D4HTX7	Vibrio_phage	7.2e-31	39.8
AZI53701.1\|20833_21037_+	hypothetical protein	NA	NA	NA	NA
AZI53731.1\|21132_21363_+	hypothetical protein	NA	NA	NA	NA
AZI53702.1\|21504_21819_-	plasmid maintenance protein CcdB	NA	NA	NA	NA
AZI53703.1\|21821_22058_-	antitoxin	NA	NA	NA	NA
AZI53704.1\|22477_23752_-	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	6.8e-145	60.2
AZI53705.1\|23760_24210_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	6.5e-26	50.8
AZI53706.1\|24498_25026_+	hypothetical protein	A0A1B0VCD0	Salmonella_phage	5.7e-37	42.9
AZI53707.1\|25065_25824_-	glycosyltransferase family 25 protein	A0A1V0S9H0	Catovirus	5.2e-07	27.2
AZI53708.1\|26160_26871_+	protein mom	A0A0C4UQZ7	Shigella_phage	4.9e-108	81.0
AZI53709.1\|27194_27383_+	hypothetical protein	NA	NA	NA	NA
AZI53710.1\|28308_28629_+	hypothetical protein	NA	NA	NA	NA
AZI53711.1\|28667_29108_+	lysozyme	A0A2I7S753	Vibrio_phage	6.0e-40	60.7
45633:45648	attR	NA	NA	NA	NA

DBSCAN-SWA_3

45262 : 50701

Dickeya_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI53714.1\|45262_46450_+	efflux RND transporter periplasmic adaptor subunit	A0A140XAI1	Dickeya_phage	2.9e-12	47.1
AZI53715.1\|46446_48387_+	MacB family efflux pump subunit	G9BWD6	Planktothrix_phage	3.9e-35	38.6
AZI53716.1\|48390_49761_+	TolC family protein	NA	NA	NA	NA
AZI53717.1\|49894_50701_-	glycosyltransferase family 25 protein	M1PWA6	Moumouvirus	8.2e-11	29.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP034148

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP034148_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034148_1

2447369-2447460

Orphan

Consensus_repeat	Method
AAGTGAGTTTCATTGATGCGCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034148_1

>merge|CP034148|1|2447369-2447460|CRISPRCasFinder
AAGTGAGTTTCATTGATGCGCCTTTGGTAGCGGATGTCGATGCCGGACTGTCACCGCCGGTGCCAGGATAAGAGAGTTTCATTGATGCGCCT

>CP034148|1|1|2447369-2447460|CRISPRCasFinder
AAGTGAGTTTCATTGATGCGCCT	TTGGTAGCGGATGTCGATGCCGGACTGTCACCGCCGGTGCCAGGAT
AAGAGAGTTTCATTGATGCGCCT

Protein	Signature genes	Signature genes Name	Protein_function
CP034148.1\|AZI51491.1\|2455126_2455756_+\|Vat-family-streptogramin-A-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
CP034148.1\|AZI51490.1\|2454471_2454870_-\|fosfomycin-resistance-glutathione-transferase	unknown	unknown	gnl\|CDD\|319908
CP034148.1\|AZI51479.1\|2443794_2444655_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
CP034148.1\|AZI52931.1\|2453518_2454232_-\|phosphonate-metabolism-transcriptional-regulator-PhnF	unknown	unknown	gnl\|CDD\|182227
CP034148.1\|AZI51473.1\|2435919_2436618_-\|D-lyxose/D-mannose-family-sugar-isomerase	unknown	unknown	gnl\|CDD\|377827
CP034148.1\|AZI51483.1\|2447982_2449119_-\|alpha-D-ribose-1-methylphosphonate-5-triphosphate-diphosphatase	unknown	unknown	gnl\|CDD\|237967
CP034148.1\|AZI51485.1\|2449829_2450591_-\|phosphonate-C-P-lyase-system-protein-PhnK	unknown	unknown	gnl\|CDD\|183280
CP034148.1\|AZI51472.1\|2435175_2435919_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|223816
CP034148.1\|AZI51481.1\|2445701_2446532_-\|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226164
CP034148.1\|AZI51489.1\|2453072_2453519_-\|phosphonate-C-P-lyase-system-protein-PhnG	unknown	unknown	gnl\|CDD\|377702
CP034148.1\|AZI51476.1\|2438682_2440197_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
CP034148.1\|AZI51486.1\|2450580_2451429_-\|carbon-phosphorus-lyase-complex-subunit-PhnJ	unknown	unknown	gnl\|CDD\|226154
CP034148.1\|AZI51487.1\|2451421_2452498_-\|carbon-phosphorus-lyase-complex-subunit-PhnI	unknown	unknown	gnl\|CDD\|377563
CP034148.1\|AZI51488.1\|2452497_2453073_-\|phosphonate-C-P-lyase-system-protein-PhnH	unknown	unknown	gnl\|CDD\|236655
CP034148.1\|AZI51484.1\|2449115_2449829_-\|phosphonate-C-P-lyase-system-protein-PhnL	unknown	unknown	gnl\|CDD\|227118
CP034148.1\|AZI51480.1\|2444748_2445675_-\|phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|132472
CP034148.1\|AZI51475.1\|2437691_2438672_-\|ribose-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226633
CP034148.1\|AZI51474.1\|2436662_2437601_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|380544
CP034148.1\|AZI51478.1\|2442913_2443798_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
CP034148.1\|AZI51477.1\|2440344_2442960_+\|response-regulator	unknown	unknown	gnl\|CDD\|237425

Protein	Function_ID	Function_description	E-value
CP034148.1\|AZI51491.1\|2455126_2455756_+\|Vat-family-streptogramin-A-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	1.46342e-74
CP034148.1\|AZI51490.1\|2454471_2454870_-\|fosfomycin-resistance-glutathione-transferase	gnl\|CDD\|319908	cd07244, FosA, fosfomycin resistant protein subfamily FosA. This subfamily family contains FosA, a fosfomycin resistant protein. FosA is a Mn(II) and K(+)-dependent glutathione transferase. Fosfomycin inhibits the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase (MurA), which catalyzes the first committed step in bacterial cell wall biosynthesis. FosA, catalyzes the addition of glutathione to the antibiotic fosfomycin, (1R,2S)-epoxypropylphosphonic acid, making it inactive. FosA is a Mn(II) dependent enzyme. It is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	9.06133e-66
CP034148.1\|AZI51479.1\|2443794_2444655_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	5.16204e-86
CP034148.1\|AZI52931.1\|2453518_2454232_-\|phosphonate-metabolism-transcriptional-regulator-PhnF	gnl\|CDD\|182227	PRK10079, PRK10079, phosphonate metabolism transcriptional regulator PhnF; Provisional.	2.69762e-157
CP034148.1\|AZI51473.1\|2435919_2436618_-\|D-lyxose/D-mannose-family-sugar-isomerase	gnl\|CDD\|377827	pfam07385, Lyx_isomer, D-lyxose isomerase. Members of this family of sugar isomerases belong to the cupin superfamily. The enzyme from Cohnella laevoribosii has been shown to be specific for D-lyxose, L-ribose, and D-mannose. E. coli sugar isomerase (EcSI) has been structurally and functionally characterized and shows a preference for D-lyxose and D-mannose.	1.64619e-136
CP034148.1\|AZI51483.1\|2447982_2449119_-\|alpha-D-ribose-1-methylphosphonate-5-triphosphate-diphosphatase	gnl\|CDD\|237967	PRK15446, PRK15446, phosphonate metabolism protein PhnM; Provisional.	0
CP034148.1\|AZI51485.1\|2449829_2450591_-\|phosphonate-C-P-lyase-system-protein-PhnK	gnl\|CDD\|183280	PRK11701, phnK, phosphonate C-P lyase system protein PhnK; Provisional.	1.78458e-179
CP034148.1\|AZI51472.1\|2435175_2435919_+\|DNA-binding-response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.74979e-72
CP034148.1\|AZI51481.1\|2445701_2446532_-\|phosphonate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226164	COG3638, COG3638, ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism].	6.62346e-113
CP034148.1\|AZI51489.1\|2453072_2453519_-\|phosphonate-C-P-lyase-system-protein-PhnG	gnl\|CDD\|377702	pfam06754, PhnG, Phosphonate metabolism protein PhnG. This family consists of several bacterial phosphonate metabolism protein PhnG sequences. In Escherichia coli, the phn operon encodes proteins responsible for the uptake and breakdown of phosphonates. The exact function of PhnG is unknown, however it is thought likely that along with six other proteins PhnG makes up the the C-P (carbon-phosphorus) lyase.	2.97194e-66
CP034148.1\|AZI51476.1\|2438682_2440197_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
CP034148.1\|AZI51486.1\|2450580_2451429_-\|carbon-phosphorus-lyase-complex-subunit-PhnJ	gnl\|CDD\|226154	COG3627, PhnJ, Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism].	0
CP034148.1\|AZI51487.1\|2451421_2452498_-\|carbon-phosphorus-lyase-complex-subunit-PhnI	gnl\|CDD\|377563	pfam05861, PhnI, Bacterial phosphonate metabolism protein (PhnI). This family consists of several Proteobacterial phosphonate metabolism protein (PhnI) sequences. Bacteria that use phosphonates as a phosphorus source must be able to break the stable carbon-phosphorus bond. In Escherichia coli phosphonates are broken down by a C-P lyase that has a broad substrate specificity. The genes for phosphonate uptake and degradation in E. coli are organized in an operon of 14 genes, named phnC to phnP. Three gene products (PhnC, PhnD and PhnE) comprise a binding protein-dependent phosphonate transporter, which also transports phosphate, phosphite, and certain phosphate esters such as phosphoserine; two gene products (PhnF and PhnO) may have a role in gene regulation; and nine gene products (PhnG, PhnH, PhnI, PhnJ, PhnK, PhnL, PhnM, PhnN, and PhnP) probably comprise a membrane-associated C-P lyase enzyme complex.	0
CP034148.1\|AZI51488.1\|2452497_2453073_-\|phosphonate-C-P-lyase-system-protein-PhnH	gnl\|CDD\|236655	PRK10147, phnH, phosphonate C-P lyase system protein PhnH.	5.60955e-77
CP034148.1\|AZI51484.1\|2449115_2449829_-\|phosphonate-C-P-lyase-system-protein-PhnL	gnl\|CDD\|227118	COG4778, PhnL, ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism].	8.45086e-133
CP034148.1\|AZI51480.1\|2444748_2445675_-\|phosphonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|132472	TIGR03431, PhnD, phosphonate ABC transporter, periplasmic phosphonate binding protein. This model is a subset of the broader subfamily of phosphate/phosphonate binding protein ABC transporter components, TIGR01098. In this model all members of the seed have support from genomic context for association with pathways for the metabolims of phosphonates, particularly the C-P lyase system, GenProp0232. This model includes the characterized phnD gene from E. coli. Note that this model does not identify all phnD-subfamily genes with evident phosphonate context, but all sequences above the trusted context may be inferred to bind phosphonate compounds even in the absence of such context. Furthermore, there is ample evidence to suggest that many other members of the TIGR01098 subfamily have a different primary function.	2.70972e-103
CP034148.1\|AZI51475.1\|2437691_2438672_-\|ribose-ABC-transporter-permease	gnl\|CDD\|226633	COG4158, COG4158, Predicted ABC-type sugar transport system, permease component [General function prediction only].	8.44839e-160
CP034148.1\|AZI51474.1\|2436662_2437601_-\|transcriptional-regulator	gnl\|CDD\|380544	cd06321, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consist of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	2.64675e-127
CP034148.1\|AZI51478.1\|2442913_2443798_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	1.49653e-82
CP034148.1\|AZI51477.1\|2440344_2442960_+\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	4.61293e-91

>CP034148.1|AZI51481.1|2445701_2446532_-|phosphonate-ABC-transporter-ATP-binding-protein
MAQALLKTVVDNDLPPASLSGQKVLSVQKLSKAYGDTQVLDQVSFDLHAGELVAVIGRSGAGKSTLLHMLNGTIEATSGAIISLHHGEADRNVVTLNSRQLREWRSQCGMIFQDFCLVPRLDVLTNVLLGRLSQTGTLKSFFKIFSDNDRAHAIELLQWMNMLPQALQRAENLSGGQMQRVAICRALMQNPKILLADEPVASLDPKNTKRIMDVLRQVSEQGISVMVNLHSIELVKSYCTRVIGIQRGVVLFDGHPSGLTDSLLHQLYGDELNQIH
>CP034148.1|AZI51480.1|2444748_2445675_-|phosphonate-ABC-transporter-substrate-binding-protein
MKLTSLALLTSVMAFGVSAADAPKQLNLGILGGQNATQQIGDNQCVKTFFDKELGVDTQMRNASDYSGVIQGLLGGKIDMVLSMSPASFASVYIQDPKAVDVVGIVVDDKDQSRGYHSVVIVKADSPYKKLEDLKGKSFGMADPDSTSGFLMPNQAFKKMFGGSVDDKYNNTFSSVTFSGGHEQDILGVLNNQFDGAVTWTSLVGDYNSGYTSGAFGRLIRMDHPDLMKQIRIIWQSPLIPNGPVLVSNKLPADFKAKVVSAIKKLDKEDHACFVKAVGGEQHIGQATVADYQNIIDMKRDLMKGSRG
>CP034148.1|AZI51479.1|2443794_2444655_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MTEFEHYYQRIRRQQKRDTLLWSLLLVALYLAAGRVAEFNLLTVWQSLPHFFDYLHEILPVLHLPLLFADGKTEGSLAYWGYRLPIQLPLIWETLQLALASTLVAVALAAVLAFFAADNTQTPVSVRMTIRAFVAFLRTMPELAWAVMFVMAFGIGAIPGFLALALHTVGSLTKLFYEAIESASDKPVRGLAACGASKLQRMRFAFWPQVKPVFLSYSFMRLEINFRSSTILGLVGAGGIGQELMTNIKLDRYDQVSITLLLILIVVSLLDTLSGQLRRRVTGDRT
>CP034148.1|AZI51478.1|2442913_2443798_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MISTVPDIALMKQQHRELFAAQPRYLRRLALMTLAVLLYYLFFFSVFGLEWSRLLMGCQQLGRYFLRMFVWHDFLNWPFGYYLSQVGITLGIVFAGTLTASLLALPLSFLAARNVMHSRTAKPLAFLMRRLFDVLRGIDMAIWGLIFVRAVGMGPLAGVLAIILQDVGLLGKLYAEGHEAVERSPGRGLGAVGANSLQKHRFGIFTQSFPQFLALSLYQIESNTRSAAVLGFVGAGGVGLVYAENMRLWNWDVVMFLTLILVVVVMVMDVISSRLRKRYISGKPVPLWQPAARD
>CP034148.1|AZI51477.1|2440344_2442960_+|response-regulator
MQRTYPWQAGARGRLLLFNLLVVSVTLMVSVVAIFGFRHAGAIQEQAQAQTLADMNGSLALARDTANVATAAVRLSQVVGALEYQSESQRLQQNQQALQQSLSLLASAPLAARQPERIARIRARSLMLEQTINSLLLTGHQRHLQRNNMLSDLWQTQILLSHIDQLVQREQRTLPDAALREQTERLITIAIRTPSPIAVIEQLQQVMAQWRNVPLTGVTGENVQRLLATQQRLLPLAEALEQSDLAIAYATYRIKALVAMLNEDISASVQQVALQSEARTLATHRELDSIIGFIALFALLALAITGYAGIYIYRNLGSSLTAIAGAMTRLAQGEQNVSVPGLQRRDELGELARAFNVFARNTASLAHTSRLLKEKSNQLESTFLAMRDGFALFDNNGQLVVWNAQYAELLGIAPHELHRGVPWQQLLAPLAVDLHDPGEPQEIRLADGRTLELRFSPIPRRGMVNTVLDRTSRKTLEEALQHSQKMKAVGQLTGGLAHDFNNLLAVIIGSLALTEGQLTPGPLASRIDRARQAADRAAQLTQRLLAFSRKQALYPRAVSVVTLVDNLQGLLQHSLLPGQQLIIDAQRPGWPAWIDASQLENALMNLVVNARDAMHQQSGEIRLRIWNQRRLEGDEKRDRVTIEVIDHGCGMSAGVREQVFEPFFTTKATGSGSGLGLSMVYGFVRQSGGQIELETAPGQGTTVRLLLPRAPEAAVAVVIAPPSPVHIETDIAAASNRLVLVLDDEPAVRQTLCEHLHQLGYLTLECGDGEEALALLRQTPDIDLLISDLMLPGEINGAEVIRQAQQNWPQLATLLISGQDLRHQPVTLPLCERLAKPWQQAQLVQALQRAWQRSERLNRAQQAATTAPASH
>CP034148.1|AZI51476.1|2438682_2440197_-|sugar-ABC-transporter-ATP-binding-protein
MTATPILEMRGITRRFGSFYALKGVDLTVYPGEVHALMGENGAGKSTLMKILAGAYTASSGEILIEGKPWALKGPKEALAAGITLIYQEINLAPNLTVAENIFLGSEIAPGGLVKRRQMAEEAQRVIDRLGAQFSAWDLVSRLSIAEQQQVEIARALQRNSRILVMDEPTAALSNRETEQLFALIKRLRSEGMAIIYISHRMAEVYELSDRVSVLRDGEYVGSLTRDQLNASELVRMMVGRPLSDLFNKDRAIPLGDIRLAVNHLTDGGKVHPSSLEVRAGEIVGLAGLVGAGRSELAQLIFGVHKPKEGEIWIDGEKVTIHSPRDAIARGIGFLTENRKEQGLFLEMAAQENIVMATLERDASYGMLNRRKGQTIASEAIASLNIRVPHAQVRAGGLSGGNQQKLLISRWVAIGPRILILDEPTRGVDVGAKSEIYRMMQEMARQGVAILMISSELPEVVGMSDRVYVMHEGTIVGELEGSHISQENIMTLATGAHSASAGEI
>CP034148.1|AZI51475.1|2437691_2438672_-|ribose-ABC-transporter-permease
MTQLARTKAPTLKRALMGDLLQTVGILPILILIVAIFGFVTPNFFTEANLLNITRQASINIVLAAGMTFVILTGGIDLSVGSMLGTTAVVALVASLDPMLASMTIPMALGAGLVMGLFNGILVAWAGLPPFIVTLGTYTALRGAAYLLADGTTVINSDINFEWIGNGYLGPVPWLIVIAFAVIAICWFILRRTTLGVHIYAVGGNIQAARLTGIKVGMVLLFVYGMSGLLSGLGGLMSASRLYSANGNLGVGYELDAIAAVILGGTSFVGGIGTITGTLIGALIIATLNNGMTLMGVSYFWQLVIKGAVIIIAVLIDKYRTRHHVS
>CP034148.1|AZI51474.1|2436662_2437601_-|transcriptional-regulator
MRFNPIVTGLLAATLFSTGLAQAKELKSIGVTVGDLANPFFVQITKGAEMKARQLAGDKVNVTLVSSGYDLGQQVGQIDNFIAAKVDMIILNAADSKGIAPAVKRARDAGIVVVAVDVAADGANATITSDNTEAGAMACKYISDRLKNKGNVVIINGPPVSAVQNRVEGCMTELKTHPDIKLLSYNQNAKGSREGGLEVMTGLLSANPKIDAVFAINDPTAIGADLAAKQAQRSEFFIVGVDGSPDGEEALKRKNSLFVATPAQDPQVMAAKAVEIGYDILQGKPAPDKPVLIPVKLIDRNNIGSYQGWTVK
>CP034148.1|AZI51473.1|2435919_2436618_-|D-lyxose/D-mannose-family-sugar-isomerase
MQRSEVNYYLQHTREFFRQQDVHLPPWADFDVSQWRAQDREVAQEILALRLGWDLTSFGAADFLQTGLTLFTLRNGSPGGQPWHKPYAEKIMHVREGQQTPMHYHPRKMEDIINRGGGNLIVELHNRDGDGLADSLVAVSLDGLRQTHAAGSQLRLSPGESVTLEAGIWHSFWGESGFGDVLVGEVSMPNDDENDNVFLTPLARFNPLEEDEAPRWLLCKDYAQWLSCARQA
>CP034148.1|AZI51472.1|2435175_2435919_+|DNA-binding-response-regulator
MKPAILVVDDDPAVCDVLQDALSEHLLTVYRCHQGREALSMLSEHPEISLVMLDMMLPDTNGLLVLQQLQRQRPEVLVIMLTGMGSEAEMVVGLEMGADDYIAKPFNPRVVVARTRAALRRSGRIAQADPEQEGWRFGGWQLDDGRCQLFNPQRELVPLTQGEYSLLRALVRHARKVLTRDQLLELTHSESLDVFDRTIDVLIMRLRRKIETNPHQPDLIRTIRGLGYVFSADVVKPDSTTRASQIA
>CP034148.1|AZI51483.1|2447982_2449119_-|alpha-D-ribose-1-methylphosphonate-5-triphosphate-diphosphatase
MIINNVRLVLENEVVTGSLEFRDERISSFSETTSQQPGALDGEGAWLMPGLVELHTDNLDKFFTPRPKVDWPSHSAMSSHDALMVSSGITTVLDAIGVGDVRDGGHRLDNLSKMIDAIRDSNRKGLNRAEHLLHLRCELPHPTTAPLFEALMGTPELALVSLMDHSPGQRQYASLTKYREYYQGKYQLNDAEMDQFEHDQLTLAAAWSQPNRQAIAGLCREHGIAIASHDDATAAHVEESHAAGSRIAEFPTTLEAARASRYRNMQVLMGAPNIVRGGSHSGNVAAWELASHGLLNILSSDYYPASLLDAAFRLADDERNSLGMAQAIALVTCNPARALGLEDRGVIAEGCRADLVLAHTAHGYPHVRHVWSKGRQVY
>CP034148.1|AZI51484.1|2449115_2449829_-|phosphonate-C-P-lyase-system-protein-PhnL
MTTITPRLRVENLCKTFVLHNQNGAALPVLHNASLTAGEGECVVLHGHSGSGKSTLLRALYGNYQPDSGHIRVAHQGEWIDMAQASARQIIALRRDTLGWVSQFLRVIPRVPTLEIVMQPLLERGVERALCEARAAELLTRLNVPQRLWSLAPSTFSGGEQQRVNIARGFIADYPVLLLDEPTASLDSVNSEAVVSLIEQARARGAAIVGIFHDRAVRERVADRLHLMHPIETGAQA
>CP034148.1|AZI51485.1|2449829_2450591_-|phosphonate-C-P-lyase-system-protein-PhnK
MYSEQPLLAVNQLTHLYAPGKGFEQVSFDLFPGEVLGIVGESGSGKTTLLQSLSARLTPQQGSILYQNRDLYQMSESDRRRLLRTEWGVVHQHPMDGLRSQVSAGGNIGERLMATGQRHYGDIRAEASRWLQAVEIDAGRIDDLPTTFSGGMQQRLQIARNLVTQPQLMFMDEPTGGLDVSVQARLLDLLRTLVRELNLAVVIVTHDLGVARLLAHRLLVMKQGRVVESGLTDRVLDDPHHPYTQLLVSSVLN
>CP034148.1|AZI51486.1|2450580_2451429_-|carbon-phosphorus-lyase-complex-subunit-PhnJ
MAELAGYNNGYLDEQTKRTIRRAILKAVAIPGYQVPFAGREMPMPYGWGTGGIQITASVIGDQDVLKVIDQGADDTTNAVSIRQFFKRVSNAATTERTADATLIQTRHRIPETPLEEDQILIFQVPIPEPLRFIEPRETETRTMHALEEYGIMQVKLYEDIARYGHIATTYAYPVRVNDRYVMDPSPIPKFDNPKMHMMPALQLFGAGREKRIYALPPYTRVESLDFDDHPFTVQQWDEPCALCGSRHSYLDEVVMDDQGTRMFVCSDTDFCHQQQEQQHVQ
>CP034148.1|AZI51487.1|2451421_2452498_-|carbon-phosphorus-lyase-complex-subunit-PhnI
MYVAVKGGEKAISNAHQLQADLRRGDRAVAELGCDQVAQQLGLAVDRVMTEGGIYDPELAALAIKQASGDLVEAIFLLRAYRTTLPRLAESTPLATGAMRIERRISAVYKDLPGGQVLGPTYDYSHRLLDFTLLANGETPAAPRDDRSVPDQCPHMFSMMSDEGLAAAEMDDGSEPVDITREPMSFPASRAARLQQLVRGDEGFLLALGYSTQRGYGRTHPFAGEIRTGTLSVSICPEELGFELEIGELLLTECEMVNGVAHSDDTAPHFTRGYGLVFGRAERKAMAMALVDRALQSREQHERVTSPAQDEEFVLSHADNVEAAGFVSHLKLPHYVDFQAELELLKQLQHDYQERNHG
>CP034148.1|AZI51488.1|2452497_2453073_-|phosphonate-C-P-lyase-system-protein-PhnH
MTLLASFNHPVADAQRAFRRILKAMSEPGVMVSLPLQQGWGALSPAATALLLTLVDQESPVWLDAEIDNEQLRNNLRFHTGAPITTQQDAPFALSHAAAQPDPTQFAAGDNMSPEKSTTLIIEVPSLNGGLTLRLSGPGLRETRAIAPQLPESVLEYLRTRPHPFPQGVDLIFTCGEAIMAVPRTTVVEVC
>CP034148.1|AZI51489.1|2453072_2453519_-|phosphonate-C-P-lyase-system-protein-PhnG
MEQQTDRQRWLSVLAHSSAALLETHWQALNLQPAFTLIRPAEIGLTRLQARMGATGKRFVMGDATVTRAVVQLSDGTLGYSYLLGRDKAHAERCALLDALLQQPETRQLLEEKIITPLAAWRDEQRQLRAREIASSKVDFFTLVRGDN
>CP034148.1|AZI52931.1|2453518_2454232_-|phosphonate-metabolism-transcriptional-regulator-PhnF
MELSRHPTTVYQAVAAQLEQALKERYRCGDYLPSEQQLADHYEVNRHTLRRAVDELVHKGLLQRRHGVGILVLMRPYDYPLHAQARFSQNLLEQGSHPTSERLLAVLRPASNDVANALGVKEGDNVIHLRTLRRANGVPLCLINHFLADLSWWPQLQQFNSGSLHDFLVEHTGKQLVRTQTRISTRRAQAKECRQLDIALHSPLLCVRTLNKTSDGAVAEYSVSLTRGDMIELTLEH
>CP034148.1|AZI51490.1|2454471_2454870_-|fosfomycin-resistance-glutathione-transferase
MLTGLNHLTLAVSNLASSLNFYTETLGFIPKAAWDHGAYLSLGELWLCLSVDTVSAGNDYTHYAFTIPGNEFDAFVERLRAAGVTEWKRNKSEGNSFYFLDPDGHKLEIHDGDLESRIRACLAQPYQGMTFF
>CP034148.1|AZI51491.1|2455126_2455756_+|Vat-family-streptogramin-A-O-acetyltransferase
MYGPDPTNPHPMEGFPQVCFIKNTVKNPNIIIGDFTYYDDPEDSENFERNVLYHFPFIGDKLIMGKFCAIARGVQFIMNGANHNMAGFSTFPFYIFGNGWETAQPQAGDLPYKGDTVIGNDVWMGYQALIMPGVKIGNGAIISSRSVVTSDVPAYSIVGGNPARVIRQRFTDETISRLEKLAWWDWPVEKITQNLPAIISADLEALPDE

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Crispr_ID: CP034148_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034148_2

2650177-2650295

Orphan

Consensus_repeat	Method
TTGCGTTGTTCAAAAACGCTCCCGGCGTTTTTAGTACGCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034148_2

>merge|CP034148|2|2650177-2650295|CRISPRCasFinder
TTGCGTTGTTCAAAAACGCTCCCGGCGTTTTTAGTACGCACCTCATCCCTGAGGTGCGCCCATAGACGGGCCAATGCATTGCGTTGTTCAAAAACGCTCCCGGCGTTTTTAGTACGCAC

>CP034148|2|2|2650177-2650295|CRISPRCasFinder
TTGCGTTGTTCAAAAACGCTCCCGGCGTTTTTAGTACGCAC	CTCATCCCTGAGGTGCGCCCATAGACGGGCCAATGCA
TTGCGTTGTTCAAAAACGCTCCCGGCGTTTTTAGTACGCAC

Protein	Signature genes	Signature genes Name	Protein_function
CP034148.1\|AZI51642.1\|2645447_2646140_+\|CidB/LrgB-family-autolysis-modulator	unknown	unknown	gnl\|CDD\|182666
CP034148.1\|AZI51647.1\|2651711_2653232_-\|galactose/methyl-galactoside-ABC-transporter-ATP-binding-protein-MglA	unknown	unknown	gnl\|CDD\|182880
CP034148.1\|AZI51653.1\|2659041_2659953_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176133
CP034148.1\|AZI51638.1\|2641053_2641509_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
CP034148.1\|AZI51641.1\|2645062_2645455_+\|murein-hydrolase-regulator-LrgA	unknown	unknown	gnl\|CDD\|234983
CP034148.1\|AZI51644.1\|2647420_2649118_+\|NAD-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|237414
CP034148.1\|AZI51654.1\|2660053_2661178_+\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176260
CP034148.1\|AZI51639.1\|2641505_2642618_-\|iron-sulfur-cluster-carrier-protein-ApbC	unknown	unknown	gnl\|CDD\|183270
CP034148.1\|AZI51637.1\|2640253_2640817_-\|alkyl-hydroperoxide-reductase-subunit-C	unknown	unknown	gnl\|CDD\|182423
CP034148.1\|AZI51640.1\|2642795_2644829_+\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234655
CP034148.1\|AZI51636.1\|2638613_2640182_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP034148.1\|AZI51652.1\|2657796_2658924_-\|YbfB/YjiJ-family-MFS-transporter	unknown	unknown	gnl\|CDD\|284247
CP034148.1\|AZI51655.1\|2661190_2662033_+\|S-formylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|178061
CP034148.1\|AZI51649.1\|2654607_2655648_-\|HTH-type-transcriptional-regulator-GalS	unknown	unknown	gnl\|CDD\|236681
CP034148.1\|AZI51645.1\|2649253_2649973_+\|outer-membrane-permeability-protein-SanA	unknown	unknown	gnl\|CDD\|182765
CP034148.1\|AZI51651.1\|2657005_2657671_-\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
CP034148.1\|AZI51646.1\|2650681_2651692_-\|galactose/methyl-galactoside-ABC-transporter-permease-MglC	unknown	unknown	gnl\|CDD\|181892
CP034148.1\|AZI51643.1\|2646260_2647151_+\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|181614
CP034148.1\|AZI51648.1\|2653300_2654296_-\|galactose/glucose-ABC-transporter-substrate-binding-protein-MglB	unknown	unknown	gnl\|CDD\|185293
CP034148.1\|AZI51650.1\|2655795_2656956_-\|DUF418-family-protein	unknown	unknown	gnl\|CDD\|182766

Protein	Function_ID	Function_description	E-value
CP034148.1\|AZI51642.1\|2645447_2646140_+\|CidB/LrgB-family-autolysis-modulator	gnl\|CDD\|182666	PRK10711, PRK10711, hypothetical protein; Provisional.	3.04353e-140
CP034148.1\|AZI51647.1\|2651711_2653232_-\|galactose/methyl-galactoside-ABC-transporter-ATP-binding-protein-MglA	gnl\|CDD\|182880	PRK10982, PRK10982, galactose/methyl galaxtoside transporter ATP-binding protein; Provisional.	0
CP034148.1\|AZI51653.1\|2659041_2659953_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176133	cd08442, PBP2_YofA_SoxR_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold. YofA is a LysR-like transcriptional regulator of cell growth in Bacillus subtillis. YofA controls cell viability and the formation of constrictions during cell division. YofaA positively regulates expression of the cell division gene ftsW, and thus is essential for cell viability during stationary-phase growth of Bacillus substilis. YofA shows significant homology to SoxR from Arthrobacter sp. TE1826. SoxR is a negative regulator for the sarcosine oxidase gene soxA. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine, which is involved in the metabolism of creatine and choline. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.98911e-83
CP034148.1\|AZI51638.1\|2641053_2641509_+\|N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	9.56683e-18
CP034148.1\|AZI51641.1\|2645062_2645455_+\|murein-hydrolase-regulator-LrgA	gnl\|CDD\|234983	PRK01821, PRK01821, hypothetical protein; Provisional.	7.22438e-57
CP034148.1\|AZI51644.1\|2647420_2649118_+\|NAD-dependent-malic-enzyme	gnl\|CDD\|237414	PRK13529, PRK13529, oxaloacetate-decarboxylating malate dehydrogenase.	0
CP034148.1\|AZI51654.1\|2660053_2661178_+\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	gnl\|CDD\|176260	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	0
CP034148.1\|AZI51639.1\|2641505_2642618_-\|iron-sulfur-cluster-carrier-protein-ApbC	gnl\|CDD\|183270	PRK11670, PRK11670, iron-sulfur cluster carrier protein ApbC.	0
CP034148.1\|AZI51637.1\|2640253_2640817_-\|alkyl-hydroperoxide-reductase-subunit-C	gnl\|CDD\|182423	PRK10382, PRK10382, alkyl hydroperoxide reductase subunit C; Provisional.	1.63046e-139
CP034148.1\|AZI51640.1\|2642795_2644829_+\|methionine--tRNA-ligase	gnl\|CDD\|234655	PRK00133, metG, methionyl-tRNA synthetase; Reviewed.	0
CP034148.1\|AZI51636.1\|2638613_2640182_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP034148.1\|AZI51652.1\|2657796_2658924_-\|YbfB/YjiJ-family-MFS-transporter	gnl\|CDD\|284247	pfam06779, MFS_4, Uncharacterized MFS-type transporter YbfB. This family represents putative bacterial membrane proteins which may be sugar transporters. Members carry twelve transmembrane regions which are characteristic of members of the major facilitator sugar-transporter superfamily.	9.86179e-68
CP034148.1\|AZI51655.1\|2661190_2662033_+\|S-formylglutathione-hydrolase	gnl\|CDD\|178061	PLN02442, PLN02442, S-formylglutathione hydrolase.	1.01274e-135
CP034148.1\|AZI51649.1\|2654607_2655648_-\|HTH-type-transcriptional-regulator-GalS	gnl\|CDD\|236681	PRK10401, PRK10401, HTH-type transcriptional regulator GalS.	0
CP034148.1\|AZI51645.1\|2649253_2649973_+\|outer-membrane-permeability-protein-SanA	gnl\|CDD\|182765	PRK10834, PRK10834, outer membrane permeability protein SanA.	0
CP034148.1\|AZI51651.1\|2657005_2657671_-\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	3.29808e-102
CP034148.1\|AZI51646.1\|2650681_2651692_-\|galactose/methyl-galactoside-ABC-transporter-permease-MglC	gnl\|CDD\|181892	PRK09478, mglC, galactose/methyl galactoside ABC transporter permease MglC.	0
CP034148.1\|AZI51643.1\|2646260_2647151_+\|cytidine-deaminase	gnl\|CDD\|181614	PRK09027, PRK09027, cytidine deaminase; Provisional.	2.67312e-180
CP034148.1\|AZI51648.1\|2653300_2654296_-\|galactose/glucose-ABC-transporter-substrate-binding-protein-MglB	gnl\|CDD\|185293	PRK15395, PRK15395, galactose/glucose ABC transporter substrate-binding protein MglB.	0
CP034148.1\|AZI51650.1\|2655795_2656956_-\|DUF418-family-protein	gnl\|CDD\|182766	PRK10835, PRK10835, hypothetical protein; Provisional.	0

>CP034148.1|AZI51645.1|2649253_2649973_+|outer-membrane-permeability-protein-SanA
MLKRVFIGLLFIILLMMATALGLDRWISWKTAPFIYENVASLPHRQVGVVLGTAKYYRTGVINQYYLYRMQGALNAYNSGKVNYLLLSGDNALQSYNEPMTMRRDLIKAGVDPADIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALQLGIQAQCYAVPSPKNMLSVRFREVGARLGALVDLFLLKREPRFLGPLVPIPAVRDVPEDAQSYPAVTPEQLLELEQKLRK
>CP034148.1|AZI51644.1|2647420_2649118_+|NAD-dependent-malic-enzyme
MELDYESKRPLYIPYAGPILLEFPLLNKGSAFSIEERNEFNLNGLLPEAVESIEEQAQRAWRQFQDFKNNNDKHVYLRNIQDTNETLFYRLLDNHLEEMMPIIYTPTVGAACEHFSEIYRRARGVFISYPNRDHIEDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRHPRITGEEYDAFVNDFIQAVKRRWPKVLLQFEDFAQKNAMPLLNRYRDEVCCFNDDIQGTAAVTVGTLIAASRAAGSRLCEQKVVFLGAGSAGCGIAEQIIAQMKSEGLSDEEARGRVMMVDRFGLLTDKLPNLLDFQSKLVQKSENLQQWDVTNDSISLLDVVRNAQPDILIGVSGQPGLFTEEIIREMHKHCKRPIVMPLSNPTSRVEATPADIIAWTDGAALVATGSPFSPVSWNGKTYPIAQCNNSYIFPGIGLGVIASGASRVTDTMLMTASRALADCSPLVNEGEGPVLPEIKDIQGVSKIIAMEVGKAAQLAGVAVVTSEDVLSQAIANNFWLPQYRHYRRTSI
>CP034148.1|AZI51643.1|2646260_2647151_+|cytidine-deaminase
MQSRFLSAFEALPSTLQTALAPLLDDPGFQAVLSADQVASLQQQTQMDADTLALALLPLAAACAVATVSHFNVGAIARGVSGNWYFGANMEFTGTPLQQTVHAEQSAITHAWLRGESQLETITVNYTPCGHCRQFMNELNSGTNIRISLPQRAISTLADYLPDAFGPRDLDITTFLMDSVDHGYVAEGDELVQAAVAAANASHAPYSQSHAGVALLTANGAIVTGRYAENAAFNPSFPPLQAALVLLNMQGGDVRQIKKAVLAEVENATLSQFAATQATLETFGCGELLQVTLYKA
>CP034148.1|AZI51642.1|2645447_2646140_+|CidB/LrgB-family-autolysis-modulator
MSEIWWSLPLTLAAFFLARKLAIRLKISLLNPLLVAMAIIIPILLLLQLPYSRYFAGSQILNQLLQPAVVALALPLYEQMHQIRARWKSIIGVCFIGSVTAMTSGTAIALWMGATPEIAATIVPKSVTTPIAMAVSGSLHGIPAISAICVLIAGVLGAVFGHTVLNLLGVKSKAARGLAIGNASHALGTARAAELDYQEGAFSSLALVICGIITSLLAPFIFPLLLHWFG
>CP034148.1|AZI51641.1|2645062_2645455_+|murein-hydrolase-regulator-LrgA
MLTVLSVCGRYLRAFIIIYLCLYAGIGIASLLPIKLPGSILGMLILFALLASQILPVSWVKPGCHLLIRYMALLFVPISVGVMSYTDILTAQFGPIVISCVVSTFLVLSIVGVSAHQLHSRRPAGESGDE
>CP034148.1|AZI51640.1|2642795_2644829_+|methionine--tRNA-ligase
MTQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRYQRMRGNQVYFICADDAHGTPIMLKAQQLGIAPEQMIAEMKSEHEADFAGFNVSYDNYHSTHGDENRELSALIYGRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSADQYGDNCEVCGATYSPTELIEPKSVVSGATPVLRDSEHFFFDLPSFSAMLQAWTRSGALQDQVANKMQEWFESGLQQWDISRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCDKRGDIDFDEFWRKDSTTELYHFIGKDIVYFHSLFWPAMLEGSNFRKPNNLFVHGYVTVNGAKMSKSRGTFIKASTWLQHLDADSLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFITKRFDGKLAAELADPALYQTFVDASEKIGDAWAGREYSRAIREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRILMTWLKPVLPSLSARAEGFLNCELSWDAIAQPLLDHQVAPFKALYSRIEMAKVEGLIEASKEDAAAASAPAASGPLADSPVGDTITIDDFAKVDMRVALIEQAELVEGSDKLLRLQLDLGGEKRQIFSGIRAAYPDPSVLVGKMTIIVANLAPRKMRFGISEGMVLSAGPGGKDLFVLSVDSGAVPGMPVK
>CP034148.1|AZI51639.1|2641505_2642618_-|iron-sulfur-cluster-carrier-protein-ApbC
MTAQSREPQTPEGLRAIVAGVLRSFEHPTLKQNLTALKALHHVAQLDGTLHVELLMPFAWASGFDVLKEQVSAELLRQTGAGAIDWRLSHDIATLKRVKNQPGVNGVKNIIAVSSGKGGVGKSSTAVNMALALAAEGARVGILDADIYGPSVPNMLGTQDQRPTSPDGTHMAPIMAHGLATNSIGYLVTDDNAMVWRGPMASKALMQLLNETLWPELDYLVLDMPPGTGDIQLTLAQNVPVTGALVVTTPQDIALIDARKGLVMFEKVNVPVLGVVENMSLHICSQCGFHEPIFGTGGAQKLVEDYQTQLLAQLPLHIDLREDLDEGQPTVIRRPDSEFTALYRQLAGRVAAQLYWQGEVIPGDIAFRAL
>CP034148.1|AZI51638.1|2641053_2641509_+|N-acetyltransferase
MEIRPFTEADRPFLRTLFLAARRHNWRWLDGSEWQLEDFDGVILGETVLVAEADGQRVGFAGLLENDNFLHSLYVDPDWQGRGVGSALLKAAEARFTSTGALKCLQKNKAAQAFYLKHGWKMISQGEGEHGGYVLMHYPLASQYASGSGRA
>CP034148.1|AZI51637.1|2640253_2640817_-|alkyl-hydroperoxide-reductase-subunit-C
MSIINTKIKPFKNAAFKNGEFIDVTEKDVEGKWSVFFFYPADFTFVCPTELGDVADHYEEFQKLGVDIYSVSTDTHFTHKAWHGSSDTIAKIQYTMIGDPTGALTRNFEIMREDEGLADRGTFIVDPEGVIQAIEITAEGIGRDASDLLRKVKAAQYVASHPGEVCPAKWKEGDATLAPSLDLVGKI
>CP034148.1|AZI51636.1|2638613_2640182_-|alkyl-hydroperoxide-reductase-subunit-F
MLDTNLKTQLKAYLEKLTKPVELIATLDEGAKSTEIRELLVDIAGLSDKVSFREENDRQVRKPSFLITNPGSNSGPRFAGSPLGHEFTSLVLALLQTGGHPSKEAQSLLDQIAALDSDFHFETYYSLSCHNCPDVVQALNLMAVINPRISHTAIDGGLFQNEIQERNVMGVPAVYLNGKEFGQGRMSLAEIVSKVDTNADKRAAEELNKRDAYEVLIIGSGPAGAAAAIYSARKGIRTGLLGERFGGQVLDTVDIENYISVPKTEGAKLAGSLRAHVDDYNVDVIESQSAIKLIPAAKEGGMHAIETASGAVLKSRSIILATGARWRNMGVPGEEEYRTKGVTYCPHCDGPLFKGKRTAVIGGGNSGVEAAIDLAGIVEHVTLLEFAGEMRADQVLQDKLRSLKNVDVILNAQTTEVKGDGTKVTGLHYIDRTTQTTHELPLSGIFVQIGLLPNTPWLEGAVERNKMGEIIIDGKCETSLKGVFAAGDCTTVPYKQIIIASGEGAKASLSAFDYLIRTKSAE
>CP034148.1|AZI51646.1|2650681_2651692_-|galactose/methyl-galactoside-ABC-transporter-permease-MglC
MKATTKKNALTWLKEGGIYVVLLVLLAIIIFQDPSFLSLMNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQAMDNANKVFPTLDTVPIPLVILTVCIIGGVIGLVNGVIIAYLKVTPFITTLGTMIIVYGINSLYYDFVGASPIAGFDTGFSKFTQGFLRFGDFKLSFITFYAVIAIIFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVNLNLIMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGSVAGVVTGVLIFTVINYGLTYIGVNPYWQYIIKGGIIIFAVALDSLKYSRKK
>CP034148.1|AZI51647.1|2651711_2653232_-|galactose/methyl-galactoside-ABC-transporter-ATP-binding-protein-MglA
MASDNTTAQREYLLEMTDVSKSFPGVKALDNVNLKVRPHSVHALMGENGAGKSTLLKCLFGIYKKDTGSILFQGKEIDYKSSKEALENGVSMVHQELNLVLQRTVMDNMWLGRYPRKGFFVDQDKMYRDTKAIFDELDIDIDPRDKVANLSVSQMQMIEIAKAFSYDAKIVIMDEPTSSLTEKEVNHLFTIIRKLKDRGCGIVYISHKMEEIFQLCDEITILRDGQWITSQPLEGLDMDKIISMMVGRSLNQRFPDRTNVPGETILEVRHLTSLRQPSIRDISFDLRKGEILGIAGLVGAKRTDIVETLFGIREKSGGTIKLHGKPINNHSANEAINHGFALVTEERRSTGIYAFLDIGFNSLISNIKKYKNSMGLLDNKRMKSDTQWVIDSMRVKTPGHHTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKREKGIIIISSEMPELLGITDRILVMSNGLVAGIVDTKTTTQNEILRLASLHL
>CP034148.1|AZI51648.1|2653300_2654296_-|galactose/glucose-ABC-transporter-substrate-binding-protein-MglB
MNKKVFTLTALVASMMFGATAHAADTRIGVTIYKYDDNFMSMVRKDIEKEAKAIGGVQLLMNDSQNDQSKQNDQIDVLMAKGVKALAINLVDPAAAAVVVDKARANDVPVVFFNKEPNAKVLAGYDKAYYVGTDSKESGIIQGQLIEKHWKATPAWDLNKDGQIQFVLLKGEPGHPDAEARTKYVIDTLNKDGLKTQQLAMDTAMWDTAQAKDKMDAWLSGPNAKKIEVVIANNDAMAMGAVEALKAHNMTSIPVFGVDALPEALALVKSGALAGTVLNDAENQAKATLDIANNLANGKAATDGTNFKMVDKIVRVPYVPVDKENLSQFVK
>CP034148.1|AZI51649.1|2654607_2655648_-|HTH-type-transcriptional-regulator-GalS
MITIRDVARQAGVSVATVSRVLNQSSAVTSDTRDAVLQAVEALGYRPNANAQALATQVSDTIGVVVMDVSDPFFGALVKAVDTVAQRVHKHVLISNSWHQEEKERHAIEVLIRQRCSALVVHAKTLPDAELADFMRHVPGMVVINRIVPGFEHRSVSLDNVTGALMASRTLLQQGHSRIGYLCSSHPIEDVAQRREGWIQAMAEQGIRPQESWIASAEPDMQGGEAAMVELLGRNLNLSAVFAYNDGMAAGALTALKDNGIQVPQHFSVIGFDDIPISRYTDPQLTTVRYPIVSMAKIATELALQGAAGLLDDTATHIFMPTLVRRHSVAQRQNVESVTNSGDSAM
>CP034148.1|AZI51650.1|2655795_2656956_-|DUF418-family-protein
MQRYHALDFIRGCAILGILLLNIVGFGLPSAAYLNPAWQGSVSLSDVWTWAISDAFAQLKFLTLFALLFGAGLQMQLPRGSRWLTARLSLLVLIGFLHGVFLWEGDILLDYGIIGLVVWRVLRDVPSTRSLMNTGILLYLVGCGVLLVFGSISDPEPTRSWLPGAADLQYEQYWKLTGGWEAIQNRLDHLSSGLMALAAQYGWQLAGLMMIGGALLRSGWLIGEFSAQHYRQAAALLLTMGLLIAVAGVAAQWLLHWEFRWTAFYLQAPRDLASPLISLGYAALCLAYWPQIARWRISYAIQCVGRMALTNYLLQSLICTTLFYRFGFYMHFTRLELVLMVPAVWLINILFSLIWLHFFAQGPLEWLWRRLTLISAGKSRITDNAR
>CP034148.1|AZI51651.1|2657005_2657671_-|GTP-cyclohydrolase-I-FolE
MSTLSQEAALVHEALLARGLETPLRAPTRDIDDNTRKSLIAGHMTEIMQLLNLDLEDDSLMETPHRIAKMYVDEVFSGLDYANFPKITVIENKMKVDEMVTVRDITLTSTCEHHFVIIDGKATVAYIPKEKVIGLSKINRIVQFFAQRPQVQERLTQQVLVALQTLLGTNNVAVSIDAVHYCVKARGVKDATSATTTTSLGGLFKSSQNTRQEFLRAVRHS
>CP034148.1|AZI51652.1|2657796_2658924_-|YbfB/YjiJ-family-MFS-transporter
MALRVALSAFLTLFVAMGIGRFAFTPQVPLMIQAHQLTLTSASLVAALNYLGYLCGSFDAMRAHRRVELRLQAGVWGAVILTLLSAFASGPWLHGAIRFLIGWSSGWAMVLVAAWSNEQLHRHGRAGLSAAVFAGPGCGIFVSGLLGVALHTLQVSAGLAWAAYGALALLLIALITRNLPRRGELHRPDQAPEPLVLDRNLKRLVLSYSLAGFGYILPATFLSQMAATRFPDGIFAQFVWPIFGGAAMIGILLGILTRRWGHSHVRLALVLWAQALGVFAAALLPGFSGLLAGALLVGGGFLSVVQLSLLCARELAPNHLRYMAGLLTTGYAIGQLVGPLLSFLSTALLHRLEPALWVAGVSLVWAGLLVWRRTG
>CP034148.1|AZI51653.1|2659041_2659953_+|LysR-family-transcriptional-regulator
MDLVQLRMFCSVAETGSLARAAEQLHRVPSNLTTRLRQLEEELGVDLFIREKQRIRLSPMGHNFLNYAQRILALSEEAMSMTRTGEPAGNFALGSMESTAATRLPGLLAAYHQRFPKVALSLITGTSGEIIDRVREGTLAAALVDGPVSHDDLNGCIAFREEMILITGLDHAPIATARDVQDDTLFAFRNSCSYRVKLESWYRDSQTAPNSVMEIQSYHAMLACVAGGAGVAMIPASVLKQMADRSRVKAHTLPPAYRDTATWLMWRRDAFTPNVEALKYLIIEQFDDRPLNDELIYPLQAAE
>CP034148.1|AZI51654.1|2660053_2661178_+|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase
MNMIKTRAAVAWAAGEPLKIEEVDLMPPQKGEVLVRIVATGVCHTDAYTLSGTDPEGVFPAILGHEGGGIVEAVGEGVTSVEVGDHVIPLYTPECGKCKYCLSGKTNLCQAIRTTQGKGLMPDGTTRFFKDGKPIFHYMGTSTFSEYTVIPEISLAKISKEAPLEEVCLLGCGVTTGMGAVMNTAKVKEGDTVAIFGLGGIGLSAVIGAKMAKAGRIIAIDLNTSKFDLARKLGATDLINPKDYDKPIQDVIVELTDGGVDFSFECIGNVNVMRSALECCHKGWGESVIIGVAGAGEEISTRPFQLVTGRVWRGSAFGGVKGRSQLPGIVQDYLDGKFALNDFITHTMPLEEINDAFDLMHEGKSIRSVVHFNK
>CP034148.1|AZI51655.1|2661190_2662033_+|S-formylglutathione-hydrolase
MASTLELLEEHRIFGGWQQRWRHQSAVLNCPMTFSIYLPGPHGDAPPPVVWFLAGLTCNDENFTSKAGAQRVAAELGLVLIMPDTSPRGEGVANDEGYDLGQGAGFYLNATQQPWASHFRMFDYLSSELPALIADNFKVSERQSIMGHSMGGHGALMLALRLGNRFASASAFAPIVNPMQVPWGQKAFQAYLGDDRATWREYDSCQLMAEVSHRLPMLIDQGDSDQFLADQLQPERLQEVANEVGFPLTLRIQPGYDHSYFFIASFVEDHLRFHAQHLLA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

872450 : 881821

Streptococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI50062.1\|872450_873563_-	porin	Q1MVN1	Enterobacteria_phage	3.3e-111	56.2
AZI50063.1\|873801_874905_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.7e-59	42.4
AZI50064.1\|874915_876169_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	3.0e-92	44.6
AZI50065.1\|876529_877261_+	chromophore lyase	A0A2I6PIE7	Escherichia_phage	1.1e-46	37.1
AZI50066.1\|877684_877963_+	hypothetical protein	NA	NA	NA	NA
AZI50067.1\|878167_878635_+	lysozyme	H9C148	Vibrio_phage	6.8e-26	44.0
AZI50068.1\|878631_878979_+	hypothetical protein	A0A286N2Q7	Klebsiella_phage	4.1e-20	45.6
AZI50069.1\|878975_879269_+	hypothetical protein	NA	NA	NA	NA
AZI50070.1\|879472_881227_+	amylovoran biosynthesis protein AmsF	A0A1S6L3G8	Erwinia_phage	1.7e-154	46.2
AZI50071.1\|881608_881821_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	9.3e-23	71.4

DBSCAN-SWA_2

1759264 : 1769487

Tupanvirus(14.29%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI50870.1\|1759264_1761193_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.7e-126	36.9
AZI50871.1\|1761196_1761748_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	6.4e-15	32.4
AZI50872.1\|1761847_1762045_+	50S ribosomal protein L35	NA	NA	NA	NA
AZI50873.1\|1762087_1762444_+	50S ribosomal protein L20	NA	NA	NA	NA
AZI52899.1\|1762566_1762611_+	pheST operon leader peptide PheM	NA	NA	NA	NA
AZI50874.1\|1762758_1763742_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	2.2e-34	37.6
AZI50875.1\|1763756_1766144_+\|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	4.1e-10	32.0
AZI50876.1\|1766148_1766451_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.3e-13	40.0
AZI50877.1\|1766630_1767614_+	vitamin B12 ABC transporter permease BtuC	NA	NA	NA	NA
AZI50878.1\|1767664_1768210_+	glutathione peroxidase	A0A1S7DM81	Molluscum_contagiosum_virus	3.5e-13	37.4
AZI50879.1\|1768210_1768960_+	vitamin B12 ABC transporter ATP-binding protein BtuD	NA	NA	NA	NA
AZI50880.1\|1769028_1769487_+	endopeptidase	A0A217EQL1	Bacillus_phage	5.5e-12	37.5

DBSCAN-SWA_3

3041386 : 3084097

uncultured_Caudovirales_phage(38.64%)

head,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZI51966.1\|3041386_3041869_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.7e-28	46.8
AZI51967.1\|3042447_3043512_+	acyltransferase	A0A2H4IYS5	uncultured_Caudovirales_phage	4.2e-140	76.8
AZI51968.1\|3043553_3043736_-	hypothetical protein	A0A2H4J1C2	uncultured_Caudovirales_phage	5.7e-21	79.7
AZI51969.1\|3043732_3044596_-	hypothetical protein	A0A2H4J9P7	uncultured_Caudovirales_phage	1.1e-56	90.6
AZI51970.1\|3044595_3045276_-	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	7.9e-108	81.9
AZI51971.1\|3045272_3046472_-	hypothetical protein	A0A2H4J5T1	uncultured_Caudovirales_phage	7.8e-159	74.1
AZI51972.1\|3046471_3046825_-	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	1.4e-52	84.6
AZI51973.1\|3046824_3047577_-	translation initiation factor IF-2	A0A2H4J8H6	uncultured_Caudovirales_phage	5.3e-113	78.8
AZI51974.1\|3047666_3048167_-	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
AZI51975.1\|3048171_3048351_-	hypothetical protein	NA	NA	NA	NA
AZI52951.1\|3048652_3048931_-	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	6.7e-29	59.3
AZI51976.1\|3048999_3050028_-	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	9.2e-100	53.8
AZI51977.1\|3050030_3050333_-	hypothetical protein	A0A0M4R5B7	Salmonella_phage	5.7e-26	57.0
AZI51978.1\|3050329_3050947_-	hypothetical protein	A0A2H4J1B3	uncultured_Caudovirales_phage	1.2e-54	62.1
AZI51979.1\|3050946_3053151_-	lytic transglycosylase domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	2.4e-278	68.3
AZI51980.1\|3053140_3053299_-	lytic transglycosylase	NA	NA	NA	NA
AZI51981.1\|3053328_3053760_-	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	4.6e-45	69.7
AZI51982.1\|3053763_3054207_-	DUF3277 family protein	A0A2H4J619	uncultured_Caudovirales_phage	5.4e-65	83.9
AZI51983.1\|3054219_3055365_-	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	2.2e-150	71.1
AZI51984.1\|3055368_3055917_-	hypothetical protein	A0A0M4R331	Salmonella_phage	4.1e-54	54.4
AZI51985.1\|3055909_3056296_-\|head,tail	head-tail adaptor	A0A0M3ULK0	Salmonella_phage	6.0e-52	78.1
AZI51986.1\|3056282_3056912_-	hypothetical protein	A0A2H4J488	uncultured_Caudovirales_phage	2.4e-26	40.1
AZI51987.1\|3056908_3057316_-	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	2.4e-43	67.2
AZI51988.1\|3057299_3057647_-	hypothetical protein	NA	NA	NA	NA
AZI51989.1\|3057687_3058626_-	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	6.0e-98	56.1
AZI51990.1\|3058640_3059138_-	hypothetical protein	A0A2H4JHM9	uncultured_Caudovirales_phage	1.6e-25	42.1
AZI51991.1\|3059137_3060379_-	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	4.2e-91	45.0
AZI51992.1\|3060444_3060633_-	hypothetical protein	NA	NA	NA	NA
AZI52952.1\|3060664_3061267_-\|head	phage head morphogenesis protein	A0A0M4REK0	Salmonella_phage	4.3e-73	67.9
AZI51993.1\|3061280_3062759_-	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	5.3e-173	60.9
AZI51994.1\|3062748_3064380_-	TerL protein	A9YWZ6	Burkholderia_phage	4.1e-235	73.4
AZI51995.1\|3064440_3064779_+	hypothetical protein	NA	NA	NA	NA
AZI51996.1\|3064991_3065957_-\|terminase	terminase small subunit	A0A0U2RXW9	Escherichia_phage	3.2e-30	38.1
AZI51997.1\|3066008_3066332_-	negative regulator GrlR	NA	NA	NA	NA
AZI51998.1\|3066683_3066959_-	hypothetical protein	NA	NA	NA	NA
AZI52953.1\|3066962_3067217_-	peptidase	B6SD44	Bacteriophage	2.4e-17	61.0
AZI51999.1\|3067104_3067506_-	hypothetical protein	S5FKR3	Shigella_phage	2.9e-09	31.5
AZI52000.1\|3067502_3068042_-	lysozyme	H9C184	Pectobacterium_phage	2.6e-77	76.7
AZI52001.1\|3068044_3068407_-	hypothetical protein	NA	NA	NA	NA
AZI52002.1\|3068902_3069751_-	antitermination protein	M9NZB0	Enterobacteria_phage	1.0e-67	51.1
AZI52003.1\|3069789_3070149_-	RusA family crossover junction endodeoxyribonuclease	K7P6W0	Enterobacteria_phage	1.2e-41	65.5
AZI52004.1\|3070145_3071528_-	replicative DNA helicase	A0A0P0ZC27	Stx2-converting_phage	3.2e-132	58.0
AZI52005.1\|3071524_3072574_-	replication protein	M1FN81	Enterobacteria_phage	2.1e-51	63.3
AZI52006.1\|3072566_3072785_-	hypothetical protein	NA	NA	NA	NA
AZI52007.1\|3072777_3072963_-	DUF4222 domain-containing protein	NA	NA	NA	NA
AZI52008.1\|3072955_3073258_-	hypothetical protein	NA	NA	NA	NA
AZI52009.1\|3073285_3073516_-	Cro/Cl family transcriptional regulator	K7PHA1	Enterobacteria_phage	8.5e-30	81.6
AZI52010.1\|3073613_3074300_+	LexA family transcriptional repressor	A0A0M4QWY1	Salmonella_phage	4.5e-50	48.3
AZI52011.1\|3074898_3075303_+	hypothetical protein	NA	NA	NA	NA
AZI52012.1\|3075424_3075637_+	hypothetical protein	NA	NA	NA	NA
AZI52013.1\|3075605_3076274_+	exodeoxyribonuclease X	A0A1W5PTR6	Pseudoalteromonas_phage	4.7e-20	31.2
AZI52014.1\|3076275_3076941_+	ATP-binding protein	G9L667	Escherichia_phage	1.9e-69	60.4
AZI52015.1\|3076940_3077633_+	hypothetical protein	A0A088C400	Shewanella_sp._phage	3.8e-25	39.5
AZI52016.1\|3077705_3078239_+	HD family hydrolase	A0A2D1GNL9	Pseudomonas_phage	5.2e-54	63.7
AZI52017.1\|3078238_3078688_+	hypothetical protein	NA	NA	NA	NA
AZI52018.1\|3078681_3078927_+	XRE family transcriptional regulator	NA	NA	NA	NA
AZI52019.1\|3079543_3080875_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.8e-84	68.2
AZI52020.1\|3080871_3082734_+	DNA cytosine methyltransferase	H9C171	Pectobacterium_phage	1.8e-218	56.9
AZI52021.1\|3082730_3082937_+	excisionase	I6PBM8	Cronobacter_phage	6.4e-21	71.0
AZI52022.1\|3082894_3084097_+	DUF3596 domain-containing protein	I6PDJ1	Cronobacter_phage	3.5e-151	66.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP034149

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP034151

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP034148

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection