CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP032135	Acinetobacter haemolyticus strain sz1652 chromosome, complete genome	2 crisprs	csa3,DEDDh,WYL,RT	1	3	5
CP032136	Acinetobacter haemolyticus strain sz1652 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0
CP032137	Acinetobacter haemolyticus strain sz1652 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP032135_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032135_2

2698486-2698601

Orphan

Consensus_repeat	Method
TGCGCAAGGCGAGCAACTGTGTTGCGAGTGAAAGGGTTAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP032135_2

>merge|CP032135|2|2698486-2698601|CRISPRCasFinder
TGCGCAAGGCGAGCAACTGTGTTGCGAGTGAAAGGGTTAAGAAAAGCAACGCTCTTGCGGAATATATTCCTCATGCGCAAGGCGAGCAACTGTGTTGTGAGTGAAAGGGTTAAGAA

>CP032135|2|2|2698486-2698601|CRISPRCasFinder
TGCGCAAGGCGAGCAACTGTGTTGCGAGTGAAAGGGTTAAGAA	AAGCAACGCTCTTGCGGAATATATTCCTCA
TGCGCAAGGCGAGCAACTGTGTTGTGAGTGAAAGGGTTAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP032135.1\|AZN69044.1\|2701302_2701665_+\|YnfA-family-protein	unknown	unknown	gnl\|CDD\|235016
CP032135.1\|AZN69708.1\|2698072_2698465_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|376861
CP032135.1\|AZN69043.1\|2699017_2701303_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|274241
CP032135.1\|AZN69049.1\|2707305_2708022_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238874
CP032135.1\|AZN69051.1\|2709203_2709668_-\|internalin	unknown	unknown	gnl\|CDD\|237284
CP032135.1\|AZN69045.1\|2702056_2703100_+\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|237190
CP032135.1\|AZN69048.1\|2706859_2707276_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
CP032135.1\|AZN69039.1\|2694324_2695854_-\|hypothetical-protein	unknown	unknown	unknown
CP032135.1\|AZN69038.1\|2692652_2694143_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|236706
CP032135.1\|AZN69033.1\|2688088_2688739_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
CP032135.1\|AZN69041.1\|2697279_2698029_+\|hypothetical-protein	unknown	unknown	unknown
CP032135.1\|AZN69035.1\|2690533_2691205_+\|ribose-5-phosphate-isomerase-RpiA	unknown	unknown	gnl\|CDD\|234816
CP032135.1\|AZN69042.1\|2698798_2698921_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|178809
CP032135.1\|AZN69037.1\|2691916_2692570_-\|CDP-alcohol-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|223632
CP032135.1\|AZN69034.1\|2688890_2690429_-\|threonine-ammonia-lyase,-biosynthetic	unknown	unknown	gnl\|CDD\|236417
CP032135.1\|AZN69036.1\|2691204_2691897_+\|M48-family-peptidase	unknown	unknown	gnl\|CDD\|307807
CP032135.1\|AZN69050.1\|2708043_2709132_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|215282
CP032135.1\|AZN69040.1\|2696148_2697198_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
CP032135.1\|AZN69047.1\|2704713_2706786_+\|NADPH-dependent-2,4-dienoyl-CoA-reductase	unknown	unknown	gnl\|CDD\|239240
CP032135.1\|AZN69046.1\|2704077_2704638_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378427

Protein	Function_ID	Function_description	E-value
CP032135.1\|AZN69044.1\|2701302_2701665_+\|YnfA-family-protein	gnl\|CDD\|235016	PRK02237, PRK02237, YnfA family protein.	1.07474e-37
CP032135.1\|AZN69708.1\|2698072_2698465_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|376861	pfam02617, ClpS, ATP-dependent Clp protease adaptor protein ClpS. In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP. ClpS directly influences the ClpAP machine by binding to the N-terminal domain of the chaperone ClpA. The degradation of ClpAP substrates, both SsrA-tagged proteins and ClpA itself, is specifically inhibited by ClpS. ClpS modifies ClpA substrate specificity, potentially redirecting degradation by ClpAP toward aggregated proteins.	1.30857e-42
CP032135.1\|AZN69046.1\|2704077_2704638_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|378427	pfam10400, Vir_act_alpha_C, Virulence activator alpha C-term. This structure is homo-dimeric, and the domain here is the C-terminal half of the structure, often associated with PadR upstream, (pfam03551), which is a transcriptional regulator.	1.70682e-16
CP032135.1\|AZN69049.1\|2707305_2708022_+\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	6.89229e-65
CP032135.1\|AZN69051.1\|2709203_2709668_-\|internalin	gnl\|CDD\|237284	PRK13108, PRK13108, prolipoprotein diacylglyceryl transferase; Reviewed.	0.00145925
CP032135.1\|AZN69045.1\|2702056_2703100_+\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|237190	PRK12755, PRK12755, phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional.	0
CP032135.1\|AZN69038.1\|2692652_2694143_-\|alkaline-phosphatase	gnl\|CDD\|236706	PRK10518, PRK10518, alkaline phosphatase; Provisional.	0
CP032135.1\|AZN69043.1\|2699017_2701303_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|274241	TIGR02639, ATP-dependent_Clp_protease_subunit, ATP-dependent Clp protease ATP-binding subunit clpA. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
CP032135.1\|AZN69033.1\|2688088_2688739_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	1.09052e-46
CP032135.1\|AZN69035.1\|2690533_2691205_+\|ribose-5-phosphate-isomerase-RpiA	gnl\|CDD\|234816	PRK00702, PRK00702, ribose-5-phosphate isomerase RpiA.	5.68045e-119
CP032135.1\|AZN69042.1\|2698798_2698921_+\|hypothetical-protein	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	0.000457309
CP032135.1\|AZN69037.1\|2691916_2692570_-\|CDP-alcohol-phosphatidyltransferase	gnl\|CDD\|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	4.57705e-05
CP032135.1\|AZN69034.1\|2688890_2690429_-\|threonine-ammonia-lyase,-biosynthetic	gnl\|CDD\|236417	PRK09224, PRK09224, threonine ammonia-lyase IlvA.	0
CP032135.1\|AZN69036.1\|2691204_2691897_+\|M48-family-peptidase	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	2.10589e-50
CP032135.1\|AZN69050.1\|2708043_2709132_+\|alpha/beta-hydrolase	gnl\|CDD\|215282	PLN02511, PLN02511, hydrolase.	3.61381e-42
CP032135.1\|AZN69040.1\|2696148_2697198_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
CP032135.1\|AZN69047.1\|2704713_2706786_+\|NADPH-dependent-2,4-dienoyl-CoA-reductase	gnl\|CDD\|239240	cd02930, DCR_FMN, 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the flavin and iron-sulfur cofactors. Metabolism of unsaturated fatty acids requires auxiliary enzymes in addition to those used in b-oxidation. After a given number of cycles through the b-oxidation pathway, those unsaturated fatty acyl-CoAs with double bonds at even-numbered carbon positions contain 2-trans, 4-cis double bonds that can not be modified by enoyl-CoA hydratase. DCR utilizes NADPH to remove the C4-C5 double bond. DCR can catalyze the reduction of both natural fatty acids with cis double bonds, as well as substrates containing trans double bonds. The reaction is initiated by hybrid transfer from NADPH to FAD, which in turn transfers electrons, one at a time, to FMN via the 4Fe-4S cluster. The fully reduced FMN provides a hydrid ion to the C5 atom of substrate, and Tyr and His are proposed to form a catalytic dyad that protonates the C4 atom of the substrate and completes the reaction.	0
CP032135.1\|AZN69048.1\|2706859_2707276_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.52388e-07

>CP032135.1|AZN69708.1|2698072_2698465_+|ATP-dependent-Clp-protease-adapter-ClpS
MNLSEVKNSFQQSGYVDWHLNPRLSDSHEEHEGEVVVQTAPPELKRPPLYAVVLMNDDYTPMDFVIEVLQSYFGMDFDQASQVMLTVHYEGKGTAGIYPRDIAETKANQVNNYARSQGHPLLCQIEPEQR
>CP032135.1|AZN69041.1|2697279_2698029_+|hypothetical-protein
MENVEPTNSPDSSVEKNKFLKSNLPLLIAAAILIGGSFMVGYTVGHRQGLTVVGYDADAEQLVEVVQKQKTALDSMNRSLNTAIQERDMAVSNADDLFKAINQANAEKTQFQGMNAIYREILKQRGGVSLTIQNLAIKSLPENAFEYQIDLVQVSPNKRRASGTVELRLIRNTEILDVPLEDKSFNFEDFERLTGRWTMPKGFTPQFIEVRLSGSGTPVIKRFSWQRGQPVELNSAFVSEIPQAEANAQ
>CP032135.1|AZN69040.1|2696148_2697198_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MISVGIVGGTGYTGVELLRLLLRHSQVQVSILTSRTEAGKRVADMFPSLRGHTDLEFSDLDLDQLKKCDVIFFATPHGVAMQHAEELIAAGTKVIDLAADFRLQNLEQFEKWYGMQHTCPEVLQSSAYGLTELNREKIKQAEVIGNPGCYPTTVQLGLAPLIKDQSGLINTQSIIVDAKSGVSGAGRKASLGMIYTENADNFKAYGVAGHRHHPEIVEALENISGQKSQFDQLVFVPHLVPMIRGMLSTIYVDLTEQGQQKDLQVLYEDFYKDERFVDVMPANSSPETRSVRGANELRIALYHPQPSKLIILVAQDNLVKGAAGQAVQNMNLMFGFDEATGLEGIGLLP
>CP032135.1|AZN69039.1|2694324_2695854_-|hypothetical-protein
MPSLMLEQRLHHHICLGLSVILLGTTLVGCGSGESKANKESQPEEVIVPKPKDFNIKVPIEMRNVVLKVFDNSDNKLVLEQNVITTTNLKVTLPYILDRNRLYRVEISTTPSSIVYNFLTSKYESMNFTWRALVKVDVSNLTQAIFINPSSEAIYQRALVRSGQLPTDENQYPMLITANQLDLATGDVDAALLSAFKNLDIPNVEATTLFHVFSPQDAHLKTALYANTYLSFGYLRQWANTYPDNSFVEFSHNLAIDLRDGYLDGKTLRGDPTPLTSLVATTPDNIDPAKNTIIGIGTTQKNAREQYAASLKQAVLELADSFNQSSTNPKNYSNLQQRTYAGVMPIADPSTPSSVRLNGAGDYRRAVGFADTSATCNGSIYPCKQGLIGINLINHSLPTIEYLIGHYQDSTQNCQLNVRADGWIELIKDNQKFRSKLDGDSTDNLLRVNKADHEYLLNSSSPEPKQGELQYEFVQLHLKENQVLSASAGLDSRKAPDQLQSTQLQCNFS
>CP032135.1|AZN69038.1|2692652_2694143_-|alkaline-phosphatase
MKLKPLLLPILITSLSFTACGGDDNNYSSSNQPLEKPRPPVTTPQFDGELLEVGANGNVSEFGGATRLKKERTQAMRESLSDKTVKHVILFIGDGTSDSEITAARNYAEGAAGYFKGLDVLPFTGSYTTYSLNKDGEVDYVTDSAASATAWASGIKTYNNALGLDIRGNHHATLLELAKKAGFATGNVTTTELQDATPAALVSHISARKCYGPNETTKRCPESALENGGLGSITEQLLTTRADVTLGGGKKTFYEVAKAGPFKDKTLLERAKLENYRIVEDLNSLKAVDSANQNQPLLGLFADGNLPVIWSGPVTQLNGHKKGAESCRDNSAFSIQTPRLAQMTEKAIELLNNNEKGFFLQVESGSIDKRNHAADPCGQIGETVQLDEAIQVALKFAKEHGETLIVVTGDHAHTSQIIPINGDSPGQTAALKTKDGVAMAINYGTAPEGSSQHHTGAQVRIAAYGPRAANVSGLLDQTDLFFIIRDALGIQQNASR
>CP032135.1|AZN69037.1|2691916_2692570_-|CDP-alcohol-phosphatidyltransferase
MLYSFKHDDSSLNLMPIAKKTPKLLIYLRLILGILIVIITLIQIKFYPIYTVIFLTLGLLSDIFDGIIARHLGVSDQNLRRLDSNIDQIFFICAISAIYLQQPEFFKQHIFPIIILIIFEAFTYIISYFKFKKEIATHTIGAKIWTLFLFALLVQITLTGQSQLLFNAVIWLGILTRIEIIAIILTLKQWQNDVPSLKQALRLRRGLEIQRNRFFNG
>CP032135.1|AZN69036.1|2691204_2691897_+|M48-family-peptidase
MVSVSVETPLPEVKVVRHARARNLRLRVEPTGIRLTVPLFCTKRQIQQFLNQSEPWLLATWAKQQHQLLQTSTFPEQLVLFAHTQPFSIVKQKQRHIFIFNWELQTLFIREIESEKALQAAVLAYAKQFLPEYLNQISREIGLPYQACTVRKPKTRWGSCTSKHDIMLNAALVLMPESIVRSVCVHELAHTKHFDHSEAFWAEVAKHDQNYIEHRKQLKQVQLPSWYYQK
>CP032135.1|AZN69035.1|2690533_2691205_+|ribose-5-phosphate-isomerase-RpiA
MSLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIDLLPELQLEAAVASSNATAERLKELGIEVVDMNSVGGLDAYVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVDDSKWVEQLGRDFPLPVEVIPMARSAVARKIVALGGDPVYREGVVTDNGNVILDVYNLNILNPIELEKTLNNIPGVVTNGIFALNAATIAIVATNNGIEERVAQ
>CP032135.1|AZN69034.1|2688890_2690429_-|threonine-ammonia-lyase,-biosynthetic
MLSRVVRQILQATVYDVAIETPLEAAPRISQKINNNIRFKREDLQPVFSFKLRGAYNRISQLPKDQLERGVICASAGNHAQGVALSGKKLGIHAIIVMPSTTPDIKVQAVKNLGGQVVLHGDSFDIANKYAKQRAEAEGLVFIPPYDDELVIAGQGTIANEILRQWRDVEYVFVAVGGGGLIAGVAAYLGEVAPHVKVIGVEYEESACLKAALAANERVILPHVGLFADGTAVAQIGELPFEMVQLRKSDNSGPIVDPTIVTVNTDEICAAIKDTYDENRSIVEPSGAMALAGIKKYVAEHQISDKNMVSIVCGANMNFDRLRYIAERTELGERKEAIYAVTIPEQKGAFLNFCRSLQGRNITEFNYRASDSNQAQVFVGISLKGGETERHEIHEMLKQQYEVDDLSDDEVAKLHIRYLIGGHANIENERLFRVEFPERPGALLTFLERLGPTHNITLFHYRNHGAAEGRVLVGLQATDAKQNPDGLIETLEQITYPYAEISDNIGYKRFLK
>CP032135.1|AZN69033.1|2688088_2688739_-|TrkA-family-potassium-uptake-protein
MAQFAVIGLGSFGATVALELTKLNHDVIGIDTQKRNVENLADKITHAVIADATDEHVLDELNVQNCDAVVVAIGEDIEASILCVLSLKNLGIDKIWVKAKTKAHHTILSHLNINKIIHPEEDMGVRVAQALNYPMVSRYMALDDDHFIIKVPIKEKLHGINLSGLMQLAPHVKLLLVKRNKDIFYETDTTFTLNKGDVLILEGLLVNLKKLSECFQ
>CP032135.1|AZN69042.1|2698798_2698921_+|hypothetical-protein
MVYILFVIEILQQYFVLNLDQYAQLMLTVDYEAKRFINVY
>CP032135.1|AZN69043.1|2699017_2701303_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLSRQLEVSLRLAVSMARQKRHEFLTVEHLLLALLDNDSAVNALKACGADIVTLRKELEEYVEQHTPKLGDNSEQAPHPTESFDRILQRAIFHVQSSGGDRTVEGADVLVAMYSERDSFAVYLLKRHQINRLTLTQYLSHGTRKDEIQVEEEVEDIEGENGASASAGPLEQYTLNLNVEAQKGKTDPLIGREKEIERAAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNGKAPKPLANAEVYSLDIGALVAGTKYRGDFEKRLKQLLNALKKNPNAILFIDEIHMIIGAGSSMGSTMDASNLIKPALANGSLRCIGSTTFQEYRQVFEKDHALSRRFQKVDVNEPSINETIEILRGLKGKFEDFHHVEYEDKALVAAVELSAKFINDRFLPDKAIDVIDEAGAQRRLKAEVDGSMISVENIEDIVSKIARIPPKTVSKDDKTVLENLERDLKRVVFGQDEAITALASAIKLSRAGLKAPDKPVGSFVFAGPTGVGKTEVTKQLAKLLGVEFVRFDMSEYMERHAVSRLIGAPPGYVGYDQGGLLTDAIHKNPHCVLLLDEIEKAHPDVFNLLLQVMDHGALTDNNGRKSDFRNVIIVLTTNIGAESISRASIGFTEQDHSADNQDAMKRAFSPEFRNRLDGVIQFKSLPTTVIESVVDKFLTELQAQLDEKQVVLEVDQSARDWLSTNGYDRLMGARPMQRLIQEHLKKPLAEMILFGELAEHGGNVAVSVKMEDGKEVGLKLEVFEDHINPSAEPA
>CP032135.1|AZN69044.1|2701302_2701665_+|YnfA-family-protein
MFEVSYSITQVLKVFGLFFITAIAEILGCYFPYLILNQGKSHWLWIPTALSLALFVWLLTLHPVASGRIYAAYGGIYIFTALMWLRYVDQVMLTRWDLLGVVVVLCGASLIILQPDGLVR
>CP032135.1|AZN69045.1|2702056_2703100_+|3-deoxy-7-phosphoheptulonate-synthase
MNALNTALTQPQTHTKESMLSLPTQLKAQYPLSATLAQQISKHRQTIQNILSGHDPRLMVITGPCSIHDPIAVLEYADRLQQLQEQVKDQIFLVMRAYIEKPRTTVGWKGFLYDPNLDGSSDLQLGLEKSRELYLQLIEKGLPIASEILSPMATGYFDDLLAWGAIGARTSESQIHREIASHMPYSIGFKNGTDGSIQIALDAIQSALNGHQFLGMTQQGLPAILHSNGNPLPHLILRGSNQGTNYDLASIQAMHFKHKHLPALVIDCSHGNSGKDPLQQPNVLKQIIAERAESKVRGVMIESHLVDGNQKISCDMTYGQSVTDGCLGWDKTEQALLDVAEQMRSKK
>CP032135.1|AZN69046.1|2704077_2704638_-|PadR-family-transcriptional-regulator
MSLAHVLLTSLLEKPSTGFELARRFDRSMGFFWNATHQQIYRELNGMLKKGWISTIEEQAANSRKKTYQIEQSGRIQLASWIEEQSEPAQLRDDLMVRLRAEAQLGGNKILPELERHLILHKEKLSLYQAIHDKDFKNNEPTNRVLFIHKMILELGIIKENEWIKWLEQMIPQLKKFEEQNEIGEK
>CP032135.1|AZN69047.1|2704713_2706786_+|NADPH-dependent-2,4-dienoyl-CoA-reductase
MQQVALASRLLARGEHMSAYPHLLEPLDLGFTTLKNRVLMGSMHIGLEEAPQGYERMAAFYAERARGDVGLIVTGGVSPNDDGVVFAHGTKLDSIEEAEKHKVVTQAVHDAGGKIAMQILHTGRYSYQANNVAPSAIQAPINPVKPKALSSAEVQQTIDDFANCAKLAQYAGYDGVEIMGSEGYLINEFIAARTNHRDDEWGGSYENRIRFPIEIVKRTRDLVGENFIIIYRLSMLDLVEGGSSLEEVIQLAKAIEQAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKLKGSVSIPLITSNRINTPEMAEYVLASGHADMISMARPMLADAEFVLKASQGRSDEINTCIGCNQACLDHIFSMTVATCLVNPRACYETELIFKEANVEKNIAVIGAGPAGLSFAVYAASRGHKVKVFDSGDQIGGQFNIAKTIPGKEEFYETLRYFKRQIELQPNIELVLNHTVTYEELSQADYDEIVVATGVTPRQLQFEGINHPKVLSYLQVLKERVPVGKRVAIIGAGGIGFDTAEYLSHEGESGSLNPEKFYAEWGIDTSYENVGGLKQPELEKSEREIYLLQRKTAAVGSGLGKTTGWIHRTGLKHRDVKMVAGASYDKVDDQGLHITVNDHQIVLEVDNVVICAGQESYTAMYDQLKADGKNVHLIGGAKEAGELDAKRAIRQGAELAAVL
>CP032135.1|AZN69048.1|2706859_2707276_+|nuclear-transport-factor-2-family-protein
MTIDTTKRALEKWHQMINTGDLANLNDLLAEDVVFRSPVAYKPYEGKQVVFFILTNVIQVFENFTYHREFYTEDGANVVLEFSADVSGKSLKGIDMIRFNAQGKIIDFEVMIRPMSGLAALAEQMGARFAQYQSNSSK
>CP032135.1|AZN69049.1|2707305_2708022_+|SGNH/GDSL-hydrolase-family-protein
MWLNLSTIVLLPVLITQGMIVRKRTPLLPEPQGNRDGLVGEGKPLSLLILGDSAAAGVGVERQEDALSGAILSELKNDYTLKWRLHARTGLTTQQVCEAIVEIDECDYDVIVTSIGVNDITKLISLGTWIKQQKQLFTQIQNRFRPKLVIVSGVPPMQHFPALPQPLAWLFGRYAEQMNNTLQQWLASQQQFRFISYDIEVFQALNISMAADGFHPSREIYAIWGKQVADIVWQSFNP
>CP032135.1|AZN69050.1|2708043_2709132_+|alpha/beta-hydrolase
MGISTLNKLKVLGSELFDFALGAELPKMYYHPQGKIKDVLEKLPQLKRKYRPTPWLSNTHVHLLYFDVIRKKTVKLEYDRIDQLTMHDGGITAIAWYGFNLPKDTPTVVMMHTITGTPESMRELVKDLHEYTGWRIALCLRRGHAGLPMPVPQISLFGSTSDLKEQLDHIQKLFPKSDLYAVGSSAGTGLLVRHLGEQAENTPFKAAFAMCPGYDTEIGFKNVHPFYSKVMTKKLFKHFIEPYKNIWSRVPSLEKVLATTSLEEFEKAYFEMAGYQDYQSYCKAINPIYVFQNIKIPLMILNAEDDPVCSIKNLEPYKDTIKQMENIVVITTKKGSHCGFYESLSVKSWASRLMADFFKNYS
>CP032135.1|AZN69051.1|2709203_2709668_-|internalin
MANKKLLICAAIATGLLLTACVKKEEPKNEEQQSEQSTETQITEQQPESVETNQQFETLESVDTEEAPAPSVETMREETENTTTEIRRETRPAQPQNNSTPTETSRTESARPAQTEPSAPRTEQPKAPKPSGPSQSEEDAVAAAIAAATPALNN

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Crispr_ID: CP032135_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP032135_3

3096385-3096652

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGCATAGGCAGCTTAGAAA	PILER-CR
GTTCACTGCCGCATAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCATAGGCAGCTTAGAAA	CRT

4 spacers

The CRISPR arrays of CP032135_3

>merge|CP032135|3|3096385-3096652|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCATAGGCAGCTTAGAAACAATTGTGAATGTACAATGATTCGAGCAGCACGTTCACTGCCGCATAGGCAGCTTAGAAAAATGCCCCGAACCAACAATAACCGTCGTCCATGTTCACTGCCGCATAGGCAGCTTAGAAAGAAGCGGATAGGCTATTACCGTACCACTTTAGGTTCACTGCCGCATAGGCAGCTTAGAAAAGGATATTCACCCAAAGTTTTCTGATTCTGTTGTTCACTGCCGCATAGGCAGATTACGAT

>CP032135|3|1|3096385-3096592|PILER-CR
GTTCACTGCCGCATAGGCAGCTTAGAAA	CAATTGTGAATGTACAATGATTCGAGCAGCAC
GTTCACTGCCGCATAGGCAGCTTAGAAA	AATGCCCCGAACCAACAATAACCGTCGTCCAT
GTTCACTGCCGCATAGGCAGCTTAGAAA	GAAGCGGATAGGCTATTACCGTACCACTTTAG
GTTCACTGCCGCATAGGCAGCTTAGAAA

>CP032135|3|3|3096385-3096652|CRISPRCasFinder
GTTCACTGCCGCATAGGCAGCTTAGAAA	CAATTGTGAATGTACAATGATTCGAGCAGCAC
GTTCACTGCCGCATAGGCAGCTTAGAAA	AATGCCCCGAACCAACAATAACCGTCGTCCAT
GTTCACTGCCGCATAGGCAGCTTAGAAA	GAAGCGGATAGGCTATTACCGTACCACTTTAG
GTTCACTGCCGCATAGGCAGCTTAGAAA	AGGATATTCACCCAAAGTTTTCTGATTCTGTT
GTTCACTGCCGCATAGGCAGATTACGAT

>CP032135|3|1|3096385-3096652|CRT
GTTCACTGCCGCATAGGCAGCTTAGAAA	CAATTGTGAATGTACAATGATTCGAGCAGCAC
GTTCACTGCCGCATAGGCAGCTTAGAAA	AATGCCCCGAACCAACAATAACCGTCGTCCAT
GTTCACTGCCGCATAGGCAGCTTAGAAA	GAAGCGGATAGGCTATTACCGTACCACTTTAG
GTTCACTGCCGCATAGGCAGCTTAGAAA	AGGATATTCACCCAAAGTTTTCTGATTCTGTT
GTTCACTGCCGCATAGGCAGATTACGAT

Protein	Signature genes	Signature genes Name	Protein_function
CP032135.1\|AZN69358.1\|3093523_3093904_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|376737
CP032135.1\|AZN69355.1\|3091862_3092498_+\|2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone-monooxygenase	unknown	unknown	gnl\|CDD\|153101
CP032135.1\|AZN69359.1\|3094009_3095308_-\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733
CP032135.1\|AZN69360.1\|3097762_3098782_-\|triacylglycerol-lipase	unknown	unknown	gnl\|CDD\|224001
CP032135.1\|AZN69366.1\|3103585_3104407_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|236467
CP032135.1\|AZN69357.1\|3093132_3093567_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-pyrophosphokinase	unknown	unknown	gnl\|CDD\|376515
CP032135.1\|AZN69356.1\|3092541_3093093_-\|DUF2799-domain-containing-protein	unknown	unknown	gnl\|CDD\|378521
CP032135.1\|AZN69361.1\|3099059_3100079_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
CP032135.1\|AZN69354.1\|3090536_3091859_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|235865
CP032135.1\|AZN69719.1\|3082559_3082919_-\|hypothetical-protein	unknown	unknown	unknown
CP032135.1\|AZN69365.1\|3102953_3103589_+\|FMN-binding-negative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225366
CP032135.1\|AZN69720.1\|3095353_3096139_-\|HesA/MoeB/ThiF-family-protein	unknown	unknown	gnl\|CDD\|238386
CP032135.1\|AZN69364.1\|3101878_3102937_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378890
CP032135.1\|AZN69367.1\|3105874_3106306_+\|hypothetical-protein	unknown	unknown	unknown
CP032135.1\|AZN69363.1\|3100965_3101736_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|187629
CP032135.1\|AZN69362.1\|3100147_3100831_-\|superoxide-dismutase	unknown	unknown	gnl\|CDD\|223678
CP032135.1\|AZN69369.1\|3107913_3108615_+\|hypothetical-protein	unknown	unknown	unknown
CP032135.1\|AZN69368.1\|3106458_3107712_-\|serine-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234571
CP032135.1\|AZN69352.1\|3083112_3087621_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225463
CP032135.1\|AZN69353.1\|3087667_3090373_-\|outer-membrane-protein-assembly-factor	unknown	unknown	gnl\|CDD\|223801

Protein	Function_ID	Function_description	E-value
CP032135.1\|AZN69358.1\|3093523_3093904_-\|dihydroneopterin-aldolase	gnl\|CDD\|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	2.14425e-34
CP032135.1\|AZN69355.1\|3091862_3092498_+\|2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone-monooxygenase	gnl\|CDD\|153101	cd01042, DMQH, Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain. Demethoxyubiquinone hydroxylases (DMQH) are members of the ferritin-like, diiron-carboxylate family which are present in eukaryotes (the CLK-1/CAT5 family) and prokaryotes (the Coq7 family). DMQH participates in one of the last steps of ubiquinone biosysnthesis and is responsible for DMQ hydroxylation, resulting in the formation of hydroxyubiquinone, a precursor of ubiquinone. CLK-1 is a mitochondrial inner membrane protein and Coq7 is a proposed interfacial integral membrane protein. Mutations in the Caenorhabditis elegans gene clk-1 affect biological timing and extend longevity. The conserved residues of a diiron center are present in this domain.	1.0496e-74
CP032135.1\|AZN69359.1\|3094009_3095308_-\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	8.80366e-91
CP032135.1\|AZN69360.1\|3097762_3098782_-\|triacylglycerol-lipase	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	3.42666e-43
CP032135.1\|AZN69366.1\|3103585_3104407_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl\|CDD\|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	1.00167e-118
CP032135.1\|AZN69357.1\|3093132_3093567_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-pyrophosphokinase	gnl\|CDD\|376515	pfam01288, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).	1.21222e-11
CP032135.1\|AZN69356.1\|3092541_3093093_-\|DUF2799-domain-containing-protein	gnl\|CDD\|378521	pfam10973, DUF2799, Protein of unknown function (DUF2799). Some members in this family of proteins are annotated as yfiL which has no known function.	4.03454e-21
CP032135.1\|AZN69361.1\|3099059_3100079_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.34791e-15
CP032135.1\|AZN69354.1\|3090536_3091859_+\|MFS-transporter	gnl\|CDD\|235865	PRK06814, PRK06814, acyl-[ACP]--phospholipid O-acyltransferase.	6.35634e-138
CP032135.1\|AZN69365.1\|3102953_3103589_+\|FMN-binding-negative-transcriptional-regulator	gnl\|CDD\|225366	COG2808, PaiB, Transcriptional regulator [Transcription].	2.61691e-77
CP032135.1\|AZN69720.1\|3095353_3096139_-\|HesA/MoeB/ThiF-family-protein	gnl\|CDD\|238386	cd00757, ThiF_MoeB_HesA_family, ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD and ThiS, respectively, on the alpha-phosphate of an ATP molecule bound at the active site of the activating enzymes, leading to the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD and ThiS. MoeB, as the MPT synthase (MoaE/MoaD complex) sulfurase, is involved in the biosynthesis of the molybdenum cofactor, a derivative of the tricyclic pterin, molybdopterin (MPT). ThiF catalyzes the adenylation of ThiS, as part of the biosynthesis pathway of thiamin pyrophosphate (vitamin B1). .	2.66532e-98
CP032135.1\|AZN69364.1\|3101878_3102937_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	1.00026e-29
CP032135.1\|AZN69363.1\|3100965_3101736_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.24748e-126
CP032135.1\|AZN69362.1\|3100147_3100831_-\|superoxide-dismutase	gnl\|CDD\|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	1.97201e-104
CP032135.1\|AZN69368.1\|3106458_3107712_-\|serine-hydroxymethyltransferase	gnl\|CDD\|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
CP032135.1\|AZN69352.1\|3083112_3087621_-\|hypothetical-protein	gnl\|CDD\|225463	COG2911, COG2911, Uncharacterized protein conserved in bacteria [Function unknown].	3.29617e-114
CP032135.1\|AZN69353.1\|3087667_3090373_-\|outer-membrane-protein-assembly-factor	gnl\|CDD\|223801	COG0729, COG0729, Outer membrane protein [Cell envelope biogenesis, outer membrane].	1.88582e-63

>CP032135.1|AZN69720.1|3095353_3096139_-|HesA/MoeB/ThiF-family-protein
MSDHLEHTFELTDDEMHLYSRQILLDGWDIEAQEKLKLANVLIVGAGGIGCTSAELLARAGVGKITIVDADTIEMSNLQRQIAFTSNDLGQYKAETLAKHLQEINPHIQVSYQNTRFDETNADELVQHQDVVLDGCDNFTTRYLVNAVCKTHQVPLISASAIGFEGQMFMVESDSACYECLFPKENQTNEGLRCAESGVLATTPVMIASLQAHHTLLFLGLGLTPLKQKLLLWNGLNLTQRILQFEKDVNCPVCQASASVN
>CP032135.1|AZN69359.1|3094009_3095308_-|AarF/ABC1/UbiB-kinase-family-protein
MKRNILVDGLRSVARIGETVIVAAQAGVKYATEKPSNAKLMRETFESLGSTYIKLGQFIASTPSLFPREYVQEFQGCLDQTPTLPFSYIQQVLAEEFEGKDLNSIFSFIDENPLASASIAQVHAAKLVTGEDVVLKVQKPGVETILYTDLNVVHWATKLLEKAVPKIKFASLSEIVDEIKTRMVREVDFIEEAQNLDDFVQYLNISGNQAATAPKVYHQFSTRRVLTMQRLYGVPLTDFDVVKQYAKDPTQVLITAMNTWFGSLMLCKSFHADLHAGNLMLLEDGRVGFIDFGIVGQLNPEVWTACMAFMDALQHTNYIAMAENMLKMGMTNQKIDTQVLAADLERLFSGVLLADPQEILSSNPADLNDIMMDMVAVGERHGIKFPRDFALLFKQMLYFDRFMRVLAPYTDIYADQRLKMVHNIEPASLLKH
>CP032135.1|AZN69358.1|3093523_3093904_-|dihydroneopterin-aldolase
MDAIIIEGLKVDTVIGCFNWERQIIQPLMLDLTIHNDLSQAARSDELEDTLNYAQICEIAAQVIQDAKPKLIEHAAQLVLEVLFNTFPSIDSISITIRKPAIIAQANAVGIRLDRNRNDFCARAGE
>CP032135.1|AZN69357.1|3093132_3093567_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-pyrophosphokinase
MIATETIFALALASNVQQLENFNFAYAQIMSLGTVEFSSIYEIPCRDGVGADYWNSACLLKSHFSVDEIVDILKKMEQQSGRVRPSHHISLDIDVIAWGESLDQMQFNPKKLPLALDVKIPLYELWPNQILQYDQNRKYPIITL
>CP032135.1|AZN69356.1|3092541_3093093_-|DUF2799-domain-containing-protein
MKTLVSISIMAVLLSGCAAMSVEQCKTANWSSVGEKDGSAGYESRLDKYYSSCQKANVVPNQALYEKGYQKGLGYYCRPESIFNEALEGRGDYRVCSIEKRETLRPYYQVAHEYYQANSEFNRSQSDVSHYLRELERKDLSAKDRDEYKKRLSDLRSNRNRVQFRYQDAVRNLERFKAEHGLP
>CP032135.1|AZN69355.1|3091862_3092498_+|2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone-monooxygenase
MRHYTGLDQLINSFDQALRSLVPGATTSQRSNPANDEASQLCVSDARHVAGLMRVNHSGEVCAQALYHGQALTAKLPHVREEMQQAAVEEQDHLAWCEDRLKELDSHTSVLNPIWYGLSYGMGAIAGIAGDKYSLGFVAETERQVSQHLQEHLQQLPEQDQRSRKILEQMNEDELHHRDTALKAGGVDLPVPVRITMTAISKLMTKTSYYI
>CP032135.1|AZN69354.1|3090536_3091859_+|MFS-transporter
MMKQDEQLMTSRRFAPMFFTQFFGALNDNVYKQALLLVITYGWIQQQSAAVSTLNNLAALLFILPYFFFSATAGQVADKYERSQLVRFLKLLEIVIMMIGTAGFLLGNLWLLLFALFLMGTHSTCFGPIKYAILPEILKPQELMSGNALFQSGTSIAILFGMILGGAVIASSAGNLLWISITVLIIACLGYLASRFILPQKVAAPDLKIDWNFFRTSFQTIKYAKSIPIVFTVLLGNSWYWFYGATYLTQIPQLTQQNLHASENVVSLLLTFFSVGIGIGSLLCRRIGGSEINIKMVPYGAIGLTVFAFYLAASLTFVPERTGELLSLGDVFSEGAVYYHVMLAVTLLGISGGFYIVPLYAMMQAYSPRSHRARVVAANNILNAVFMVSSAIFSILILSILKIDIKILFSITAVLSAIFSFWLLTRLKPLLKNAPTTLED
>CP032135.1|AZN69353.1|3087667_3090373_-|outer-membrane-protein-assembly-factor
MPSKSKFKQSTLVHSMHLIFKMQSFPKLICSGFLISYCISVAYADEEAVVVAENSTIERMKDQVKSIPSPEIPYETFNLSSEYYNPAQDSVAALKQQEEAPSQIDTLKPIQLDENLEHLPVIAVDQNMANEIFQIAEEAKNDALAYRENVAKNPELVVNEASQSELTEISNPPVNIDRLMQEIQADSQIIVEANESGRTLADLQPKTEQVEEKAGFFKRIVNRFRPENLLGAERVPRISADVSGAPPALATNIKAKLSSFTQEAFEDFNVALPQLRSLTNQAAQAVGYYDARFSFEKLSDSRVKVTVEPNEPVKIDKQNIEFTGEGENAPQFQVIRLIPEQDEGDIFNHGKYEATKTKITNAASDNGYFDAYWRLHDVKISQPEKTAEINLKYDTGERYKLKAVEYKMSDPSKPLPLTQKVLDSLAPWKDGDDYAFWRVNVLANNLTNTRYFNYTLVDTIKPDAIQPPLDLPPDLQALVDQQRVEQSQLFSAQQKADIARQQVVSAEEVTQDVVDESQFSGSEPTPAYSLARSMPNIQNDETERQALEEQARLEKKIPVVVTLNADRLNTIETGVGYGTDTGARIRSQYRRAFVNKHGHSFDANIEVSEIRQSIDGRYSIPYKHPLNDYFNLVGGYERETRDNIGPNVELLVESAVVGGERVIKNPLGDWQHTFGLRYRLDRLTGKGDVDVSELPDAFRAAGTNSEQESLLLGYEISKTNSNTRLNPTKGFKQTYKVELGTESILSDANMAILTAGWRFIYSLGENDNHQFVGRGDASYIFTDDFDKVPYNLRFFTGGDQSLRGFDYKSLSPEEDGYKIGGQALGVGSLEYNYQFKDGWRAAVFSDFGNAFDKQFSNPTEYSVGVGIRWRSPIGPIRLDVASGISNDNRPIRLHFFIGPQL
>CP032135.1|AZN69352.1|3083112_3087621_-|hypothetical-protein
MTEDVEQQQTPSTGPKRERRILRSILLMVLIILLLLVSSLLVMMSTDKGSRFLLDRVLQTQKIIHYEYESGNLLRGIILKNVLVQLEAVDVSLDRADVSLGWRAILKKEIHLSHADVANLKIINKKPPSGEPFGFDPIKLPFILRIDEASLDHLEIQTATAKINFDDIYLKDALWSETKLKFKDSRMDMGYLAVKDATGQIDFSGKYPLNAKADLIIPALNSIDIETIKVVATGSLDTLRAGVATLTPDLLTGWAVLHPVRDQVPMQGELFFRNYHLPILKEQKLFAKDGIARFKGNIEKLVLSLDTDLKGEKIPEGKYNALMETDLTDQLNIQDFNGQLMGGSVSLKGLVNWKDHVSWDLKGRLDRLNAKDETLPQIAQDFLPPSLDANISSTGMLKNGMSVNAQLAFDKYETWQVKLNQSEQKNNQPEPMLLDVAWQGIDRAVPYIGWLSSAEGHTNITLKDDQQDIYVATTVRPHEQGLLPAGKYDAHIDLKGSLLNVENFSYVAEKGRLDGQAKVKLPTDKQQLAWQAQLKAKDFNPQTVALAAPVNLLNGEILASGFAKPNQQIIQFERIDLQGQLAQANQKETVVLQGKATTALMFDDVQAGGGFKSFAVDYDGSLNALNQGNDLLKINIAGTPTNIKINELKHDGVAGKLFATGTVDLQDKIGWNIETSLVRFKPQYFVSSLKGEVSGHVKTQGVWSDKVKRIDIRQLNAAGFLNNRPVRGRGNLSLLLDSNQTGFLPQQFEANDLFFAYGQNQLQATGNAQSLRFKVNAPALYELYPGLRGRAYGSLNVQSQPRLSATANLVVDGFAFNDLASVKSLRIQGQLPTSETTPTQLTATIDQLRSGKRELENATLNLTGTRRAHLLKLETKNARTNFYVQLAGGFNQNNDWLGQIQKGKFSSRRVRLVQNQNTPVIYTTARTELYVGQHCWQSAESQLCLDQPARISPEKGNFSFVTKDLDLKDFAAFMPEGIAVTGQLNGYAKASWAKGTRPKLDSRLVTRKGEIGLAAEDPQDPATTVTYDELSLIAKSISDGLLFRVDMKTPDIGTGYANVVIDPFQTGMPMRGEIAFDDVQLKVFKPFIKDVRSMAGTLALAGKINGTLTQPQFTGEMRLKNGAISMISLPVNLTNMQLYSSIRQDTASIDGAFNSGQGVGRIKGRFDWKDNPHLSLTLKGDNLLVRQAPMITAIVQPDLSLDVYPFDQRLSLRGTIDVPRARISMPESSATVVNVSPDVRVVHQGQDLLATLRAAKPWDIRADMTVTLGNQVIFQGFESNIPLVGRLHLSQRGLETAMRANGAIGVSQKVKIEAYGQSLDLNRAIARFNGPLANPTLDIDANKSVQGSMVGVRVAGTATVPNVQIYNDAGLSEQEALNALLTGRINEGGSGLSNTEGFKSDVNNTIAAAGISMGLGGTRALTNQIGRTFGLSGLALDAQGTGDDTQVSLTGYITPDLFIRYGVGVFTPVNKLTLRYQMNRRLYLEASQSLERAIDVFYNWRF
>CP032135.1|AZN69719.1|3082559_3082919_-|hypothetical-protein
MKKVLLIAIGLVLVGCADKKPLTPEEKWHGFCVSVGNAARSITLDRQNAIEKQQAIEHAGKIEDKTIHKFILQIIDEVYEIPVDQLKSDPSAIRDEMKQKFTEQCLATPHDELPNYKSF
>CP032135.1|AZN69360.1|3097762_3098782_-|triacylglycerol-lipase
MKKKYLNAIVLTTGMLISGGSVVHAGLFSFLSPKASWQNCDVKSCSVGGSTNVTSSYAKTKYPIVLAHGMSGFSAVGPLQYWHGITEDLVSNGANVFVTQQAAFNSSEVRGEQLLLQTKQILAISGAEKVNLVGHSHGTHSIRYVAGLMPDKVASVTAVAGPGKGSNVADVVYDFTQSPVGPIAAPVISAGVNAFGALIGIGSGNYYDQDSLAGLWSLTTAGAAEFNQRFPAGIPMTACGSGRELESNGVRYYSWTGISPFTNALDPFDYALTATSLLIPGDSDGLVPRCSSHLGTVIRDNYAFNHLDEVNQVLGLVGFLQNPVTPFRLQANRLKNLNL
>CP032135.1|AZN69361.1|3099059_3100079_+|AraC-family-transcriptional-regulator
MSIPRLHHPHFISSSYVHLLSEVVARWNISAEELFWGTGVEIEKLHDINYKISLTSFKKVIARTIDLTQEQGIGFYASTQLKISSHGLLGFTVAIAKNPLDAIQTINQFVSLQCSFVDLHFVVENELAYYNIIYDKSVMDFNDPCDLQAYEFSCVFFLTGFVHLVRFFIPDFKPSIDLQCKCPEYFSRFKNILASSFAEIHYEQPHTRLISSAKFLETPLSMSDPLTSEKFKLLCQKELDELVATQDILYRVKNLIDDQHQGLLNIDQVAQKLNLTKRTLQRMLQEQNVSFQILYDQVRKAKAQKLLLNPFITKDEIARNLGYSSLSSFNRAYKRWENQ
>CP032135.1|AZN69362.1|3100147_3100831_-|superoxide-dismutase
MRYLNKGLLTLLVCSSVSISAFANFTQAPLPYKSDALEPAIDQQTMEIHYGKHHKAYVDNLNAQIKTYPELDKLNIEQIQQQISKYNAAVRNNGGGHFNHTFFWESLAPTDRTGKVSPKLLKKINQDFGSFKAFQEQFNQAATSRFGSGWAWLIVNPQGKLEITSTPNQDNPLMDIAEKKGQPLLGLDVWEHAYYLKYQNRRADYTNAFWSVVNWNKVNDRYQKASK
>CP032135.1|AZN69363.1|3100965_3101736_-|3-hydroxyacyl-CoA-dehydrogenase
MKIQGKHFVITGGGSGLGAATAEYLVEKGASVTLVDMNAEVGEQQAKAIGDQAEFVKLDVTDEQAAEQFFKEVVEKHGSLHGLINCAGVGPSAKVVGKDGVHDLAMFSKVLHINVTGTFNMLRYAADAMSKNSVEEGDEDRGVIVNTASVAAFDGQIGQAAYSASKGAVVAMTLPIARELARHSIRIMTIAPGIMETPMLKGLPQNVQDALGQMVPYPSRLGRPEEFARLVAHIAENAYLNGEVIRLDGAIRMAAK
>CP032135.1|AZN69364.1|3101878_3102937_+|AraC-family-transcriptional-regulator
MSKNPPLDLNSAKDTISNALIREALSVAASRGLNIVNIANRAGISAELLTSAKARIPVTQCAQLWVELAESMNDEFLGMDSHPMRRGSYKLLAKIAFEADTLEQAIREILKFLSLVLDDIHGELVQNGSKAYLILHDRDQPKRMFTYSTFLMLVHSLMCWLSDQRIAFLKMSFKCHQPVEIQDYRIRFCENIQFHATQNCIEFDAHYLKHKIKKDKQALNDFLRHTPYNLIVRFKNENSLSLQIRRQLLLQPPSEWAELKDIAQQLNMSTATIQRRLKHEGVSYQQLKNDIRCDIAIERLSKTNDSIQSISDDLNFHDPSAFHRAFKKWSGVSPGSYRKSAPNKQNRLHHLG
>CP032135.1|AZN69365.1|3102953_3103589_+|FMN-binding-negative-transcriptional-regulator
MYIPQIFKETRQDVLHDLIRQYPFATLITQNNAGLDAMHLPVELLVDDEKNATLVAHIAKNNPLHTQIDNGAEVLVIFQGQQGYISPNWYPSKQQHHQHVPTWNYQVVHVKGKIYFSQDEKVLRGILARLTRTHEAKQDKPWKMSDAPSEYIAEELRHIVAVEIQVSEMVGQFKMSQNRDPIDAIGIVEGLEQQGNTELAQVVKHSTQSNN
>CP032135.1|AZN69366.1|3103585_3104407_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MNIAQALEIKGEIDSYERQEAAWLLEHILGVNSLELKLRLEQELTEIQEQAYLDGLARIEQGEPLAYVTGSQPFWTLDLKVTHDTLVPRPDTEILVETVLKLSLDPQANIVDLGTGTGAIALALASERPQWSVTATDIYQPTLEVAQENALKHGLSQVKFACGAWFEALVEQQQFDLIVSNPPYIDPDDVHMQKLKSEPERALIAANHGLADIEIIIAQGKAWLKAKGWIALEHGYDQGRAVREIFELHGFEQIQTIKDYGSNDRVSLAQKAG
>CP032135.1|AZN69367.1|3105874_3106306_+|hypothetical-protein
MKANILLLGAILASSTIATTTYADNATRVAATSALGSVVGTAIGKEIGGHNGALIGSAVGGAGGAAAASSKRTRTEAAIGGGLGGVGGYAVGKNVGGTTGGYIGAAAGAAGGAALGRQVGQDRYYDSRQNQKKKWKKKKHRRH
>CP032135.1|AZN69368.1|3106458_3107712_-|serine-hydroxymethyltransferase
MFANISIAEFDPKLAQAIASEGERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGGCEYVDVIEQLAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVLGMSLAHGGHLTHGAKVSFSGKTYNAVQYGLNPETGEIDYEEVERLALEHKPRMIVAGFSAYSQVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRSGLILAKANEEIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSEEFKTYQQQVVKNAQAMAEVLMARGYDVVSGGTENHLFLLSLIKQDVTGKDADAWLGAAHITVNKNAVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADIIDSKGDEKVIAEVKAKVEAVCAKFPVYAN
>CP032135.1|AZN69369.1|3107913_3108615_+|hypothetical-protein
MIRINGKIQHLEIYDFYCVRNRKYETQIEQEQAALAQTLIANLFDVDARVLAYRINKTYKIYSFQIAHHTVMGITEHIFFQEGDELYVVIDPNSFTDISLAYAIYHPEQNLIYSLPQHGFTIEGLRKRQKTIGLSFFILSFLINIFFLVKWESYEEIFIESALAILVSLSLALIAYFSAGLLYKQAVQESMQIYKTFGFNNVEKIDFKSEVYVHKPTRIICSDIAYLKVKIQE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP032135_2	2.1\|2698529\|30\|CP032135\|CRISPRCasFinder	2698529-2698558	30	CP032135.1	1706223-1706252	0	1.0

1. spacer 2.1|2698529|30|CP032135|CRISPRCasFinder matches to position: 1706223-1706252, mismatch: 0, identity: 1.0

aagcaacgctcttgcggaatatattcctca	CRISPR spacer
aagcaacgctcttgcggaatatattcctca	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP032135_3	3.2\|3096473\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096473-3096504	32	MG674163	Acinetobacter phage SH-Ab 15497, complete genome	21431-21462	2	0.938
CP032135_2	2.1\|2698529\|30\|CP032135\|CRISPRCasFinder	2698529-2698558	30	MH617182	Microviridae sp. isolate cthf910, complete genome	3432-3461	8	0.733
CP032135_3	3.2\|3096473\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096473-3096504	32	KX190834	Bacillus phage BMBtpLA3, complete genome	7046-7077	8	0.75
CP032135_3	3.2\|3096473\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096473-3096504	32	NC_011645	Bacillus phage TP21-L, complete genome	27439-27470	8	0.75
CP032135_3	3.1\|3096413\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096413-3096444	32	CP045836	Lysinibacillus pakistanensis strain LZH-9 plasmid unnamed, complete sequence	21803-21834	10	0.688
CP032135_3	3.1\|3096413\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096413-3096444	32	CP045836	Lysinibacillus pakistanensis strain LZH-9 plasmid unnamed, complete sequence	55228-55259	10	0.688
CP032135_3	3.1\|3096413\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096413-3096444	32	NZ_CP040811	Escherichia fergusonii strain EFCF056 plasmid pEF06, complete sequence	22141-22172	10	0.688
CP032135_3	3.1\|3096413\|32\|CP032135\|PILER-CR,CRISPRCasFinder,CRT	3096413-3096444	32	NZ_CP040811	Escherichia fergusonii strain EFCF056 plasmid pEF06, complete sequence	55584-55615	10	0.688

1. spacer 3.2|3096473|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to MG674163 (Acinetobacter phage SH-Ab 15497, complete genome) position: , mismatch: 2, identity: 0.938

aatgccccgaaccaacaataaccgtcgtccat	CRISPR spacer
agtgccccgaaccagcaataaccgtcgtccat	Protospacer
*.************.*****************

2. spacer 2.1|2698529|30|CP032135|CRISPRCasFinder matches to MH617182 (Microviridae sp. isolate cthf910, complete genome) position: , mismatch: 8, identity: 0.733

aagcaacgctcttgcggaatatattcctca	CRISPR spacer
gagcaacgctctcgcggaatgtatgacctt	Protospacer
.***********.*******.***  *..

3. spacer 3.2|3096473|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to KX190834 (Bacillus phage BMBtpLA3, complete genome) position: , mismatch: 8, identity: 0.75

aatgccccgaaccaacaataaccgtcgtccat	CRISPR spacer
aagcgtcccaaccaacaataaccgtcttctct	Protospacer
**   .** ***************** **. *

4. spacer 3.2|3096473|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to NC_011645 (Bacillus phage TP21-L, complete genome) position: , mismatch: 8, identity: 0.75

aatgccccgaaccaacaataaccgtcgtccat	CRISPR spacer
aagcgtcccaaccaacaataaccgtcttctct	Protospacer
**   .** ***************** **. *

5. spacer 3.1|3096413|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to CP045836 (Lysinibacillus pakistanensis strain LZH-9 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

caattgtgaatgtacaatgattcgagcagcac	CRISPR spacer
ttcgcgggattgtacaattattcgagcagcga	Protospacer
.   .* ** ******** ***********.

6. spacer 3.1|3096413|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to CP045836 (Lysinibacillus pakistanensis strain LZH-9 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

caattgtgaatgtacaatgattcgagcagcac	CRISPR spacer
ttcgcgggattgtacaattattcgagcagcga	Protospacer
.   .* ** ******** ***********.

7. spacer 3.1|3096413|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040811 (Escherichia fergusonii strain EFCF056 plasmid pEF06, complete sequence) position: , mismatch: 10, identity: 0.688

caattgtgaatgtacaatgattcgagcagcac	CRISPR spacer
ttcgcgggattgtacaattattcgagcagcga	Protospacer
.   .* ** ******** ***********.

8. spacer 3.1|3096413|32|CP032135|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040811 (Escherichia fergusonii strain EFCF056 plasmid pEF06, complete sequence) position: , mismatch: 10, identity: 0.688

caattgtgaatgtacaatgattcgagcagcac	CRISPR spacer
ttcgcgggattgtacaattattcgagcagcga	Protospacer
.   .* ** ******** ***********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

79211 : 87234

uncultured_Mediterranean_phage(28.57%)

holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN66996.1\|79211_80837_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	8.3e-95	36.7
AZN66997.1\|80829_81861_+	hypothetical protein	NA	NA	NA	NA
AZN66998.1\|82797_83061_-	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	3.1e-20	56.2
AZN66999.1\|83062_83554_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	5.3e-29	44.9
AZN67000.1\|83869_85087_+	DUF4102 domain-containing protein	A0A0D4DBR3	Acinetobacter_phage	1.5e-120	53.4
AZN67001.1\|85083_85302_+	hypothetical protein	NA	NA	NA	NA
AZN67002.1\|85479_86004_-	secretion activator protein	A0A2H4J8Q8	uncultured_Caudovirales_phage	1.4e-72	75.0
AZN69622.1\|86003_86282_-\|holin	holin	C7BGD7	Burkholderia_phage	1.1e-20	53.9
AZN67003.1\|86430_87234_-	hypothetical protein	A0A0A0RR02	Acinetobacter_phage	1.3e-13	49.3

DBSCAN-SWA_2

100862 : 122085

Acinetobacter_phage(30.0%)

terminase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN67020.1\|100862_102092_-	hypothetical protein	C8CLI7	Xylella_phage	8.5e-60	36.7
AZN67021.1\|102171_102915_-	hypothetical protein	NA	NA	NA	NA
AZN67022.1\|102901_105154_-\|portal	portal protein p19	F8TUN9	EBPR_podovirus	2.9e-61	31.2
AZN67023.1\|105150_106440_-\|terminase	PBSX family phage terminase large subunit	L7TP33	Pseudomonas_virus	1.7e-79	42.5
AZN67024.1\|106414_106951_-\|terminase	terminase small subunit	G0ZND3	Cronobacter_phage	2.7e-34	49.0
AZN67025.1\|106990_107221_-	hypothetical protein	NA	NA	NA	NA
AZN67026.1\|107755_108034_-	DUF968 domain-containing protein	A0A1B1P9J2	Acinetobacter_phage	1.7e-24	65.2
AZN67027.1\|107975_108188_-	hypothetical protein	A0A1B1P9J1	Acinetobacter_phage	1.6e-19	74.2
AZN67028.1\|108191_108398_-	hypothetical protein	NA	NA	NA	NA
AZN69623.1\|108449_108776_-	hypothetical protein	A0A0S4L5D5	Pseudomonas_phage	2.3e-28	65.4
AZN67029.1\|108980_109550_-	GIY-YIG nuclease family protein	A0A0E3D9F9	Bacillus_phage	4.7e-13	34.1
AZN67030.1\|109644_110085_-	hypothetical protein	NA	NA	NA	NA
AZN67031.1\|110095_110317_-	hypothetical protein	NA	NA	NA	NA
AZN67032.1\|110326_110731_-	DUF1064 domain-containing protein	A0A0R6PIZ9	Moraxella_phage	1.3e-25	55.4
AZN67033.1\|110727_111036_-	hypothetical protein	NA	NA	NA	NA
AZN67034.1\|111032_111347_-	hypothetical protein	NA	NA	NA	NA
AZN67035.1\|111346_111535_-	hypothetical protein	NA	NA	NA	NA
AZN67036.1\|111534_111822_-	hypothetical protein	E2GLW0	Acinetobacter_phage	2.8e-06	41.3
AZN67037.1\|111818_112058_-	DUF3310 domain-containing protein	A0A0R6PHM6	Moraxella_phage	2.8e-28	82.4
AZN67038.1\|112054_112372_-	hypothetical protein	NA	NA	NA	NA
AZN67039.1\|112368_112608_-	hypothetical protein	NA	NA	NA	NA
AZN67040.1\|112604_113987_-	replicative DNA helicase	I2GUI4	Acinetobacter_phage	2.8e-75	37.2
AZN67041.1\|113983_114874_-	DNA-binding protein	A0A1B1P9I2	Acinetobacter_phage	6.1e-124	83.1
AZN67042.1\|115059_115290_-	hypothetical protein	NA	NA	NA	NA
AZN67043.1\|115401_116118_+	helix-turn-helix transcriptional regulator	A0A2H4J6Q0	uncultured_Caudovirales_phage	8.8e-25	35.8
AZN67044.1\|116313_116634_+	hypothetical protein	NA	NA	NA	NA
AZN67045.1\|116630_117029_+	hypothetical protein	NA	NA	NA	NA
AZN67046.1\|117255_118305_+	hypothetical protein	A0A1B0VN89	Pseudomonas_phage	3.8e-24	41.4
AZN67047.1\|118315_119089_+	phage recombination protein Bet	A0A088CBI3	Shigella_phage	2.6e-54	62.5
AZN67048.1\|119069_119678_+	exonuclease	A0A2H4J882	uncultured_Caudovirales_phage	4.6e-83	74.7
AZN67049.1\|119736_120009_+	hypothetical protein	K4HYN5	Acinetobacter_phage	6.3e-32	79.0
AZN67050.1\|120005_120347_+	hypothetical protein	NA	NA	NA	NA
AZN67051.1\|120339_120768_+	hypothetical protein	NA	NA	NA	NA
AZN67052.1\|120764_121037_+	hypothetical protein	E9N433	Salmonella_virus	7.5e-17	46.2
AZN69624.1\|121042_121309_+	hypothetical protein	NA	NA	NA	NA
AZN67053.1\|121311_121512_+	AlpA family phage regulatory protein	NA	NA	NA	NA
AZN67054.1\|121611_122085_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.5e-23	42.3

DBSCAN-SWA_3

259863 : 314704

Faecalibacterium_phage(33.33%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN67163.1\|259863_260889_-\|transposase	IS30-like element ISAba125 family transposase	A0A2K9V2S9	Faecalibacterium_phage	5.7e-25	30.1
AZN67164.1\|261181_261466_+	hypothetical protein	NA	NA	NA	NA
AZN67165.1\|261520_261715_+	hypothetical protein	NA	NA	NA	NA
AZN69630.1\|262804_263167_-	hypothetical protein	NA	NA	NA	NA
AZN67166.1\|266926_267565_-	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AZN67167.1\|267937_268750_-	subclass B1 metallo-beta-lactamase NDM-1	NA	NA	NA	NA
AZN67168.1\|268850_269876_-\|transposase	IS30-like element ISAba125 family transposase	A0A2K9V2S9	Faecalibacterium_phage	2.0e-25	30.4
AZN67169.1\|269940_270561_+	hypothetical protein	NA	NA	NA	NA
AZN67170.1\|270573_271251_+	hypothetical protein	NA	NA	NA	NA
AZN67171.1\|271446_271674_+	DNA-binding protein	NA	NA	NA	NA
AZN67172.1\|271892_272606_+	hypothetical protein	NA	NA	NA	NA
AZN67173.1\|272602_274441_+\|transposase	transposase	NA	NA	NA	NA
AZN67174.1\|274442_275396_+\|transposase	transposase	NA	NA	NA	NA
AZN67175.1\|275392_277384_+	hypothetical protein	NA	NA	NA	NA
AZN67176.1\|277569_277758_-	antitoxin	NA	NA	NA	NA
AZN67177.1\|277767_279012_-	hypothetical protein	NA	NA	NA	NA
AZN67178.1\|279406_280420_+	SIR2 family protein	NA	NA	NA	NA
AZN67179.1\|282514_282877_+	hypothetical protein	NA	NA	NA	NA
AZN67180.1\|283057_284671_-	hypothetical protein	NA	NA	NA	NA
AZN67181.1\|285012_286356_-	DUF3526 domain-containing protein	NA	NA	NA	NA
AZN69631.1\|287778_288507_-	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	8.4e-15	30.8
AZN67182.1\|289200_290415_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
AZN67183.1\|290541_291927_-	amino acid permease	NA	NA	NA	NA
AZN67184.1\|292281_293589_+	fumarylacetoacetase	NA	NA	NA	NA
AZN67185.1\|293575_294208_+	maleylacetoacetate isomerase	NA	NA	NA	NA
AZN67186.1\|295133_295913_+	IclR family transcriptional regulator	NA	NA	NA	NA
AZN67187.1\|295983_297039_-	4-hydroxyphenylpyruvate dioxygenase	NA	NA	NA	NA
AZN67188.1\|297757_299398_+	malate dehydrogenase (quinone)	NA	NA	NA	NA
AZN67189.1\|299480_300731_+	MFS transporter	NA	NA	NA	NA
AZN67190.1\|300758_301214_+	hypothetical protein	NA	NA	NA	NA
AZN67191.1\|303438_305049_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	7.3e-19	24.7
AZN67192.1\|305864_307334_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
AZN67193.1\|307414_309109_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	5.8e-59	31.2
AZN67194.1\|309172_309961_+	hypothetical protein	NA	NA	NA	NA
AZN67195.1\|310010_311186_-	zinc-binding dehydrogenase	NA	NA	NA	NA
AZN67196.1\|311484_312207_+	hypothetical protein	NA	NA	NA	NA
AZN67197.1\|312211_313045_+	hypothetical protein	NA	NA	NA	NA
AZN67198.1\|313099_314704_-\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	2.2e-63	31.5

DBSCAN-SWA_4

1849572 : 1927018

uncultured_Caudovirales_phage(14.29%)

tRNA,plate,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN68367.1\|1849572_1850586_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AZN68368.1\|1850754_1851672_+	DUF808 domain-containing protein	NA	NA	NA	NA
AZN68369.1\|1852732_1854232_+	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	3.1e-19	33.3
AZN69683.1\|1856986_1865104_+	type I secretion C-terminal target domain-containing protein	NA	NA	NA	NA
AZN68370.1\|1866902_1870094_+	hypothetical protein	NA	NA	NA	NA
AZN68371.1\|1870101_1870986_+	hypothetical protein	NA	NA	NA	NA
AZN68372.1\|1870947_1872038_-\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
AZN68373.1\|1872079_1872808_+	glycosyltransferase	NA	NA	NA	NA
AZN68374.1\|1872862_1873600_-\|protease	metalloprotease	NA	NA	NA	NA
AZN68375.1\|1873682_1873997_+	methyltransferase	NA	NA	NA	NA
AZN68376.1\|1874093_1874597_+	hypothetical protein	B9UDL3	Salmonella_phage	3.3e-18	40.9
AZN68377.1\|1874671_1875109_-	universal stress protein	NA	NA	NA	NA
AZN68378.1\|1875334_1875961_-	chloramphenicol acetyltransferase CAT	NA	NA	NA	NA
AZN68379.1\|1876023_1876239_-	hypothetical protein	NA	NA	NA	NA
AZN68380.1\|1876339_1876816_-	transcription elongation factor GreA	NA	NA	NA	NA
AZN68381.1\|1876908_1880142_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
AZN68382.1\|1880156_1881296_-	carbamoyl-phosphate synthase small subunit	NA	NA	NA	NA
AZN68383.1\|1881656_1882199_+	hypothetical protein	NA	NA	NA	NA
AZN68384.1\|1882250_1882787_-	hypothetical protein	NA	NA	NA	NA
AZN68385.1\|1882792_1883119_-	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
AZN68386.1\|1883383_1884034_+	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
AZN68387.1\|1884171_1886067_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	M4QMW8	Micromonas_pusilla_virus	2.6e-108	46.8
AZN68388.1\|1886200_1887064_+	dihydropteroate synthase	NA	NA	NA	NA
AZN68389.1\|1887176_1887935_+	SIMPL domain-containing protein	NA	NA	NA	NA
AZN68390.1\|1889772_1890087_+	hypothetical protein	NA	NA	NA	NA
AZN68391.1\|1890117_1891716_-	peptidase S15	NA	NA	NA	NA
AZN68392.1\|1893262_1893865_+	nicotinamide riboside transporter PnuC	A0A0S1S1B4	Klebsiella_phage	3.4e-09	27.4
AZN68393.1\|1893914_1895054_-	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
AZN68394.1\|1895260_1896874_-	sulfatase	NA	NA	NA	NA
AZN68395.1\|1900595_1901933_+	magnesium transporter	NA	NA	NA	NA
AZN68396.1\|1902009_1902588_+	DUF4112 domain-containing protein	NA	NA	NA	NA
AZN68397.1\|1902651_1903557_-\|protease	protease HtpX	NA	NA	NA	NA
AZN68398.1\|1903774_1904638_-	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	1.0e-35	53.7
AZN68399.1\|1905134_1906040_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	3.1e-91	64.2
AZN68400.1\|1906236_1906620_+	SCP-2 sterol transfer family protein	NA	NA	NA	NA
AZN68401.1\|1906666_1907776_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AZN68402.1\|1908150_1908627_+	transcription elongation factor GreB	NA	NA	NA	NA
AZN68403.1\|1909276_1910581_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
AZN68404.1\|1910740_1911631_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZN68405.1\|1911766_1913182_+	aspartate ammonia-lyase	NA	NA	NA	NA
AZN68406.1\|1913408_1914365_-	M15 family peptidase	U5PVY5	Bacillus_phage	7.0e-09	34.1
AZN68407.1\|1914368_1914968_-	hypothetical protein	NA	NA	NA	NA
AZN68408.1\|1914978_1915788_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
AZN68409.1\|1915798_1917163_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
AZN68410.1\|1917179_1918277_-	type VI secretion system protein TssA	NA	NA	NA	NA
AZN68411.1\|1921332_1922097_+	hypothetical protein	NA	NA	NA	NA
AZN68412.1\|1922113_1922617_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
AZN68413.1\|1922609_1924091_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
AZN68414.1\|1924142_1924646_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
AZN68415.1\|1924720_1925197_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
AZN68416.1\|1925209_1927018_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_5

2998635 : 3008501

Pseudomonas_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN69278.1\|2998635_3000813_+\|transposase	transposase	A0A125RN93	Pseudomonas_phage	2.4e-113	40.4
AZN69279.1\|3000862_3001603_+	ATP-binding protein	A0A0A1IVZ3	Pseudomonas_phage	2.0e-56	49.2
AZN69280.1\|3001612_3002299_+	hypothetical protein	A0A1B1P6Z8	Rhodovulum_phage	5.2e-14	29.8
AZN69281.1\|3002295_3002541_+	hypothetical protein	NA	NA	NA	NA
AZN69282.1\|3002506_3002878_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZN69283.1\|3002861_3003203_+	hypothetical protein	NA	NA	NA	NA
AZN69284.1\|3003199_3003817_+	DUF3164 family protein	Q6QIE4	Burkholderia_phage	1.7e-56	56.5
AZN69285.1\|3003832_3004018_+	hypothetical protein	NA	NA	NA	NA
AZN69286.1\|3004483_3004696_+	hypothetical protein	NA	NA	NA	NA
AZN69287.1\|3004692_3004896_+	hypothetical protein	NA	NA	NA	NA
AZN69288.1\|3004897_3005314_+	hypothetical protein	NA	NA	NA	NA
AZN69289.1\|3005310_3005724_+	regulatory protein GemA	A0A0M5MRZ7	Ralstonia_phage	4.3e-24	45.1
AZN69290.1\|3005716_3006130_+	hypothetical protein	B7SDY2	Pseudomonas_virus	3.1e-06	30.5
AZN69291.1\|3006260_3006725_+	peptidase M15	A0A0R6PGV9	Moraxella_phage	1.3e-32	52.6
AZN69292.1\|3006727_3006946_+	hypothetical protein	NA	NA	NA	NA
AZN69293.1\|3006966_3007317_+	hypothetical protein	NA	NA	NA	NA
AZN69294.1\|3007300_3007645_+	hypothetical protein	Q6QIC4	Burkholderia_phage	3.6e-08	54.3
AZN69295.1\|3007641_3007953_+	hypothetical protein	A0A2H4JGU5	uncultured_Caudovirales_phage	3.8e-25	51.0
AZN69296.1\|3007955_3008501_+	DUF3486 family protein	A4JWJ3	Burkholderia_virus	8.2e-39	45.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP032137

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

63628 : 84822

uncultured_virus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN69814.1\|63628_65233_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	4.3e-144	54.0
AZN69815.1\|65249_65411_-\|transposase	transposase	NA	NA	NA	NA
AZN69816.1\|65313_65565_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZN69817.1\|65668_66214_-	autotransporter outer membrane beta-barrel domain-containing protein	Q9EV15	Enterobacteria_phage	1.8e-17	32.5
AZN69818.1\|66474_67221_+\|transposase	IS5-like element ISAba31 family transposase	A0A0N9SJT9	Paenibacillus_phage	2.5e-14	38.2
AZN69819.1\|68551_68767_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	7.7e-17	68.3
AZN69820.1\|68864_69092_+	hypothetical protein	NA	NA	NA	NA
AZN69821.1\|69158_69356_+	hypothetical protein	NA	NA	NA	NA
AZN69822.1\|69542_69863_+	hypothetical protein	NA	NA	NA	NA
AZN69823.1\|69855_70128_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZN69824.1\|70707_71274_+	hypothetical protein	NA	NA	NA	NA
AZN69825.1\|71382_71997_+	hypothetical protein	NA	NA	NA	NA
AZN69826.1\|72152_72377_-	DUF2798 domain-containing protein	NA	NA	NA	NA
AZN69827.1\|72390_72723_-	hypothetical protein	NA	NA	NA	NA
AZN69828.1\|72966_73578_+	resolvase	NA	NA	NA	NA
AZN69829.1\|73950_74334_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AZN69830.1\|74276_74666_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AZN69831.1\|74740_76324_+\|transposase	IS66-like element ISAba25 family transposase	A0A218MNE7	uncultured_virus	2.1e-143	53.8
AZN69832.1\|77004_77466_-	septicolysin	NA	NA	NA	NA
AZN69833.1\|77636_78020_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AZN69834.1\|77962_78352_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AZN69835.1\|78426_80010_+\|transposase	IS66-like element ISAba25 family transposase	A0A218MNE7	uncultured_virus	2.1e-143	53.8
AZN69836.1\|80059_80239_+	hypothetical protein	NA	NA	NA	NA
AZN69837.1\|80501_80837_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AZN69838.1\|81034_81316_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	2.6e-12	44.4
AZN69839.1\|81316_81619_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	1.2e-20	49.0
AZN69840.1\|81763_82192_+	hypothetical protein	NA	NA	NA	NA
AZN69841.1\|82561_83137_-	DNA-binding protein	NA	NA	NA	NA
AZN69842.1\|84071_84822_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.5e-24	44.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP032135

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP032137

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection