CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP022301	Acinetobacter johnsonii strain IC001 plasmid pIC001C, complete sequence	1 crisprs	NA	0	1	0
CP022298	Acinetobacter johnsonii strain IC001 chromosome, complete genome	2 crisprs	cas14j,csa3,RT,cas3,DEDDh,WYL,c2c9_V-U4,cas3f,cas1,TnsE_C	1	0	12
CP022300	Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence	2 crisprs	NA	0	3	0
CP022302	Acinetobacter johnsonii strain IC001 plasmid pIC001D, complete sequence	0 crisprs	NA	0	0	0
CP022299	Acinetobacter johnsonii strain IC001 plasmid pIC001A, complete sequence	0 crisprs	NA	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP022301_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022301_1

1474-1572

Orphan

Consensus_repeat	Method
ATCAAAGAAAGGCAAAAAAGGTCAAATAAAAGCAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022301_1

>merge|CP022301|1|1474-1572|CRISPRCasFinder
ATCAAAGAAAGGCAAAAAAGGTCAAATAAAAGCAAACGGTTTTATCAAAAATCAGCAAATAAGATCAAAGAAAGGCAAAAAAGGTCAAATAAAAGCAAA

>CP022301|1|1|1474-1572|CRISPRCasFinder
ATCAAAGAAAGGCAAAAAAGGTCAAATAAAAGCAAA	CGGTTTTATCAAAAATCAGCAAATAAG
ATCAAAGAAAGGCAAAAAAGGTCAAATAAAAGCAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP022301.1\|AZN65867.1\|869_1202_+\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	unknown	unknown	gnl\|CDD\|379750
CP022301.1\|AZN65868.1\|1228_1432_+\|hypothetical-protein	unknown	unknown	unknown
CP022301.1\|AZN65871.1\|3197_3698_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377024
CP022301.1\|AZN65874.1\|5853_6810_-\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|376444
CP022301.1\|AZN65866.1\|616_892_+\|type-II-toxin-antitoxin-system-antitoxin,-RelB/DinJ-family	unknown	unknown	gnl\|CDD\|274102
CP022301.1\|AZN65869.1\|2102_2573_-\|hypothetical-protein	unknown	unknown	unknown
CP022301.1\|AZN65870.1\|2866_3088_+\|hypothetical-protein	unknown	unknown	unknown
CP022301.1\|AZN65872.1\|3921_4899_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274743
CP022301.1\|AZN65873.1\|5306_5861_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|378935

Protein	Function_ID	Function_description	E-value
CP022301.1\|AZN65867.1\|869_1202_+\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	2.19214e-33
CP022301.1\|AZN65873.1\|5306_5861_-\|DNA-binding-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.00145909
CP022301.1\|AZN65874.1\|5853_6810_-\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	9.33387e-63
CP022301.1\|AZN65866.1\|616_892_+\|type-II-toxin-antitoxin-system-antitoxin,-RelB/DinJ-family	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	1.74588e-23
CP022301.1\|AZN65871.1\|3197_3698_+\|hypothetical-protein	gnl\|CDD\|377024	pfam03350, UPF0114, Uncharacterized protein family, UPF0114.	6.88203e-06
CP022301.1\|AZN65872.1\|3921_4899_+\|hypothetical-protein	gnl\|CDD\|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	1.57883e-141

>CP022301.1|AZN65868.1|1228_1432_+|hypothetical-protein
MNEAEKERLKEIFRISKGIVDHEFSQEVIDACKPYEDARHQRILNGETTLEQEEAALMAEWRRLNPK
>CP022301.1|AZN65867.1|869_1202_+|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family
MTSKKTAKDKRAVLPRSSDYTKEFLADWQRLSRSGRYDMAKLKQVMMLIIANDEPLGAEWVDHALSGNQWKNCRELHVGGDFLLIYRIEPLSKFEMVVFVRTGTHSELFK
>CP022301.1|AZN65866.1|616_892_+|type-II-toxin-antitoxin-system-antitoxin,-RelB/DinJ-family
MTSQTSMLHVRIDDETKLQAQQALKSMGMSVSDAVRIFLTRVVAEQAIPFDVRVPNTTTVAAMNEADALIQAKKARFETVEDLFNDLEKNS
>CP022301.1|AZN65869.1|2102_2573_-|hypothetical-protein
MQQPVLQIKEDTIEQNLFWEINGSIDLAIIPGNTIKGIPHDLPIRLQNGYAKGRNGFGYLHILRNHGQEFNRLRPPTDVFGFLVKKLGQGGSFHHQTDKRKGLYLAMLPSGVIILDYVAKGRDSFFTIITAYTTNRSIDGKEIGRYISTFQVKPKK
>CP022301.1|AZN65870.1|2866_3088_+|hypothetical-protein
MRPLFLCYKNKELVYFRELSYGGMPIAELRHLTGRIGELYVAMMTLGQLADSVNQRGYDVVSSTGRLCCTKIS
>CP022301.1|AZN65871.1|3197_3698_+|hypothetical-protein
MLQNFFEKGRFLVIIVIINCILSSIFLYLSTIYLLIDAIIFIIKNIYATNFEVKIVVVKFLKILDVSLIAITFHLISAGFYKLFIQQAIFDNSSFLKTLSINKFHDLKVIILHLSIVVIVILFLEDLVVFGGTLANLYAGISSSLVILAIIFTCKLFDNDHHKDDE
>CP022301.1|AZN65872.1|3921_4899_+|hypothetical-protein
MDVLFSNFLDKPVWMWIFFILIVLVLLILDLGVFHRKVREIGVKESLALSAFYITLGLLFGAWVWWYLGPTAGINYVTGFVIEKSLAMDNIFVIAMIFSYFSIPRIYQHRVLFWGIIGVIFLRAIMIGVGATLVSQFSWVLYIFAAFLIFTGIKMWLSVDKEYEVGNSPILNFIKKRFRVTEQLHAEKFWVKKIDPKTNQLTWFMTPLFLALIMIEFVDLIFAIDSVPAIFAITTDPFIVYTSNIFAILGLRALYFALSAMVDRFHYLKYALAVLLVFIGSKIFIADGLGIAKIPPPVSLSITFIILFTGILYSLWKTKDQSTHR
>CP022301.1|AZN65873.1|5306_5861_-|DNA-binding-protein
MAKLSLSEVSNRFNVSRSTLYRAIKEGRISRSSDGLFDIAEVIRCFGEPIKKHEQKQEVNQSKDDADLRQLVDFMKKEIESYKDREKRYLDQIDRFQLLLGHKESEEKMSHDAPVTHPNDAPCDNSSETRETIDNNKYGEISTSHETPVTHPNETPKHVSKTHYETKKKRGLFGRVLNAVFDND
>CP022301.1|AZN65874.1|5853_6810_-|RepB-family-plasmid-replication-initiator-protein
MKNDLVVKDNALINASYNLEVTEQRLILLSIIRARETGQGISSDSKLEIHASDYASRFDVTKEAAYNALKNAVNNLFERKFSFKEIHKDTNKEIVVKSRWVSRIAYVDDLATLEVTFAPDVVPLITRLEKHFTSYQLKQVAQLTSKYAIRLYEFLIAWRDVGKTPVISLSEFREKLGLDINEYQKMVNFKSRVLEPAIKQINELTDIHVKYEQYKTGRSISGLSFTFKHKKIDSIPSERDPNTVDLFTQMTDAQRHMFANKLSELPEMGRYSQGTESYPQFAIRIAEMLKNPDRIKELYPYLKKVGYMPSSKKDVANG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	NZ_CP022301	Acinetobacter johnsonii strain IC001 plasmid pIC001C, complete sequence	1510-1536	0	1.0
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	MH892363	Streptococcus phage SW14, complete genome	24454-24480	5	0.815
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	MH892376	Streptococcus phage SW1151, complete genome	23831-23857	5	0.815
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	MG708273	Streptococcus phage vB_SthS_VA698, partial genome	6520-6546	5	0.815
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	NC_031020	Morganella phage vB_MmoM_MP1, complete genome	61897-61923	5	0.815
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	MN693163	Marine virus AFVG_25M177, complete genome	21949-21975	6	0.778
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	132413-132439	6	0.778
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	MN850656	Flavobacterium phage fF4, complete genome	9636-9662	6	0.778
CP022301_1	1.1\|1510\|27\|CP022301\|CRISPRCasFinder	1510-1536	27	NZ_CP010903	Acinetobacter nosocomialis strain 6411 plasmid p6411-66.409kb, complete sequence	59199-59225	7	0.741

1. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to NZ_CP022301 (Acinetobacter johnsonii strain IC001 plasmid pIC001C, complete sequence) position: , mismatch: 0, identity: 1.0

cggttttatcaaaaatcagcaaataag	CRISPR spacer
cggttttatcaaaaatcagcaaataag	Protospacer
***************************

2. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to MH892363 (Streptococcus phage SW14, complete genome) position: , mismatch: 5, identity: 0.815

cggttttatcaaaaatcagcaaataag	CRISPR spacer
catttttatcaaaaaaaagcaaataaa	Protospacer
*. ************  *********.

3. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to MH892376 (Streptococcus phage SW1151, complete genome) position: , mismatch: 5, identity: 0.815

cggttttatcaaaaatcagcaaataag	CRISPR spacer
catttttatcaaaaaaaagcaaataaa	Protospacer
*. ************  *********.

4. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to MG708273 (Streptococcus phage vB_SthS_VA698, partial genome) position: , mismatch: 5, identity: 0.815

cggttttatcaaaaatcagcaaataag	CRISPR spacer
catttttatcaaaaaaaagcaaataaa	Protospacer
*. ************  *********.

5. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to NC_031020 (Morganella phage vB_MmoM_MP1, complete genome) position: , mismatch: 5, identity: 0.815

cggttttatcaaaaatcagcaaataag	CRISPR spacer
cacttttttcaaaaatcagaaaataaa	Protospacer
*. **** *********** ******.

6. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to MN693163 (Marine virus AFVG_25M177, complete genome) position: , mismatch: 6, identity: 0.778

cggttttatcaaaaatcagcaaataag	CRISPR spacer
aggttttctcaaaaatcagcaaactta	Protospacer
 ****** ***************.  .

7. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 6, identity: 0.778

cggttttatcaaaaatcagcaaataag	CRISPR spacer
tatttttatgaaaaataagcaaataaa	Protospacer
.. ****** ****** *********.

8. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to MN850656 (Flavobacterium phage fF4, complete genome) position: , mismatch: 6, identity: 0.778

cggttttatcaaaaatcagcaaataag	CRISPR spacer
aaattttatcaaaaatcaggaaattat	Protospacer
 ..**************** **** *

9. spacer 1.1|1510|27|CP022301|CRISPRCasFinder matches to NZ_CP010903 (Acinetobacter nosocomialis strain 6411 plasmid p6411-66.409kb, complete sequence) position: , mismatch: 7, identity: 0.741

cggttttatcaaaaatcagcaaataag	CRISPR spacer
tttttttatcaaaaaacagcaaatttc	Protospacer
.  ************ ********

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Crispr_ID: CP022298_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022298_1

814876-814968

Orphan

Consensus_repeat	Method
TTTTAAAGCAGTCCGAAAAACTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022298_1

>merge|CP022298|1|814876-814968|CRISPRCasFinder
TTTTAAAGCAGTCCGAAAAACTAAAGTTTTCTAAATTCCCGATATTAGGTTTTATAAGGTTCTATTCTCTTTTAAAGCAGTCCGCAAAACTAA

>CP022298|1|1|814876-814968|CRISPRCasFinder
TTTTAAAGCAGTCCGAAAAACTAA	AGTTTTCTAAATTCCCGATATTAGGTTTTATAAGGTTCTATTCTC
TTTTAAAGCAGTCCGCAAAACTAA

Protein	Signature genes	Signature genes Name	Protein_function
CP022298.1\|AZN63264.1\|834834_837309_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377008
CP022298.1\|AZN63253.1\|813939_814128_-\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN63257.1\|820795_822015_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
CP022298.1\|AZN63246.1\|807127_807529_+\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN63262.1\|832789_833191_-\|DDE-transposase-family-protein	unknown	unknown	gnl\|CDD\|372649
CP022298.1\|AZN63258.1\|828903_830123_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
CP022298.1\|AZN63261.1\|832377_832848_-\|IS5/IS1182-family-transposase	unknown	unknown	gnl\|CDD\|372577
CP022298.1\|AZN63248.1\|809941_810454_+\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN63249.1\|810490_810817_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|136097
CP022298.1\|AZN63259.1\|830294_831439_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
CP022298.1\|AZN63252.1\|812717_813383_-\|DNA-transfer-protein-p32	unknown	unknown	unknown
CP022298.1\|AZN63260.1\|832107_832419_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377008
CP022298.1\|AZN63263.1\|833245_834838_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377857
CP022298.1\|AZN63250.1\|810935_811982_+\|(p)ppGpp-synthetase	unknown	unknown	gnl\|CDD\|143389
CP022298.1\|AZN63245.1\|806823_807135_+\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN63254.1\|814124_814418_-\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN63256.1\|817201_819805_+\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN63247.1\|807521_809639_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379041
CP022298.1\|AZN63255.1\|815833_816970_+\|integrase	unknown	unknown	gnl\|CDD\|170049
CP022298.1\|AZN63251.1\|812267_812636_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP022298.1\|AZN63264.1\|834834_837309_+\|hypothetical-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	4.69231e-10
CP022298.1\|AZN63257.1\|820795_822015_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.16403e-100
CP022298.1\|AZN63262.1\|832789_833191_-\|DDE-transposase-family-protein	gnl\|CDD\|372649	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease. This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.	3.079e-16
CP022298.1\|AZN63247.1\|807521_809639_+\|hypothetical-protein	gnl\|CDD\|379041	pfam13148, DUF3987, Protein of unknown function (DUF3987). A family of uncharacterized proteins found by clustering human gut metagenomic sequences.	7.24144e-45
CP022298.1\|AZN63249.1\|810490_810817_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|136097	PRK06863, PRK06863, single-stranded DNA-binding protein; Provisional.	1.1311e-43
CP022298.1\|AZN63260.1\|832107_832419_+\|hypothetical-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	6.01848e-16
CP022298.1\|AZN63263.1\|833245_834838_+\|hypothetical-protein	gnl\|CDD\|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	0.00135771
CP022298.1\|AZN63250.1\|810935_811982_+\|(p)ppGpp-synthetase	gnl\|CDD\|143389	cd05399, NT_Rel-Spo_like, Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases. This family includes the catalytic domains of Escherichia coli ppGpp synthetase (RelA), ppGpp synthetase/hydrolase (SpoT), and related proteins. RelA synthesizes (p)ppGpp in response to amino-acid starvation and in association with ribosomes. (p)ppGpp triggers the bacterial stringent response. SpoT catalyzes (p)ppGpp synthesis under carbon limitation in a ribosome-independent manner. It also catalyzes (p)ppGpp degradation. Gram-negative bacteria have two enzymes involved in (p)ppGpp metabolism while most Gram-positive organisms have a single Rel-Spo enzyme (Rel), which both synthesizes and degrades (p)ppGpp. The Arabidopsis thaliana Rel-Spo proteins, At-RSH1,-2, and-3 appear to regulate a rapid (p)ppGpp-mediated response to pathogens and other stresses. This catalytic domain is found in association with an N-terminal HD domain and a C-terminal metal dependent phosphohydrolase domain (TGS). Some Rel-Spo proteins also have a C-terminal regulatory ACT domain. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition.Two of the three catalytic carboxylates are found in Rel-Spo enzymes, with the second carboxylate of the DXD motif missing. Evidence supports a single-cation synthetase mechanism.	9.63377e-28
CP022298.1\|AZN63255.1\|815833_816970_+\|integrase	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	1.21366e-70
CP022298.1\|AZN63259.1\|830294_831439_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.95192e-40
CP022298.1\|AZN63258.1\|828903_830123_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.58507e-100
CP022298.1\|AZN63261.1\|832377_832848_-\|IS5/IS1182-family-transposase	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.19761e-18

>CP022298.1|AZN63254.1|814124_814418_-|hypothetical-protein
MTNKTKTYDAADMHDLASLSESDMNWMCTAISHIRKEVLKLNKLAESGKEVSQYHFSEIVTQLDMYEYLAEDRHRNHAKGAEAYKAEWEAAKQKANA
>CP022298.1|AZN63253.1|813939_814128_-|hypothetical-protein
MNKPNDTPKTRYEKKRKQKLVSFNTENSHDADLLAHANKLDDFSGWVKEQLNEDMKEKKGSQ
>CP022298.1|AZN63252.1|812717_813383_-|DNA-transfer-protein-p32
MVAAAVIAGGAAIAGGAMASSASKKAAKTQAASADRASQIQQENFEQTREDLMPYKQAGDTSLKQLMGQMGANGYFNQTYAGQDIYSDPSYQFRLQQGQNAIQSSAAAQGGLLSGATLKALQNYGQESASQEYSNAYNRFNADQTNRYNRLSNLVGIGQNAAAQVGNAGAQTAQAVANNTMAGANSIAAGQVGSANAWSNTANDLGSMAAAYGIMNKKGVI
>CP022298.1|AZN63251.1|812267_812636_-|hypothetical-protein
MKKIILICGLLTSSFSFGADWVVLDRSHGQESQIDMSSIKKLPSDKRLVWYRSITKAEEAKYVYLTFRAEIDCTRETLQNNDLVIHINDKHISQTTVENPKPFSPPPESSGQKIIQTTCKVP
>CP022298.1|AZN63250.1|810935_811982_+|(p)ppGpp-synthetase
MTQHALEVPTKSSVRKAGDKLKDPSLDHTEALDILSKWRALHSYPINTFQATLRRKVEALGLKKAIIAQRLKRLPSIVSKLQRINGMKLDRMQDIGGVRIVLSSTKDVYALYENLLQSNRRFEHEPQLPPKDYIQQPKSDGYRCLHQVFKYKSRTHPELNGLCIELQIRTHLQHAWATAVETLGIVEKLSFKTGEGSEDFKTFFKLTSALFSIKEATPILDEYSHYSFDELKEEARLLEQKLQIFIKLRGLSITNRHIESATSESADYHLIELSRVDDIWRVSLTPFTKAQLDFAEQMYELREQKTKNAPNSDVVLVSVGSLKQLKKAYPNYFLDTEEFIKQLSIMLK
>CP022298.1|AZN63249.1|810490_810817_+|single-stranded-DNA-binding-protein
MANLNRVTVMGVLGRDPETKQFPNGGSVTTFSVATTEFWKDKTTGERKEATEWHRIATSNRLAEIASKYLKKGGKVYIEGSLRTRKYKDKSGSEKEITEIRADELQLL
>CP022298.1|AZN63248.1|809941_810454_+|hypothetical-protein
MSIGKALELIRMAKSYQCVLYWDPPDRIRFASQSLIPDELLSEVKAHKHVLIEYFKHTDRDLTPLLGRAFDGYLYCLNQMRERHSSAALSDCHVSTLYWRSTVKATLQVSNPELKLIEMLLIQSEQLKYLDDSNTALITPEQEQQKYSTDADANTAFNYLLSKHRQFVYC
>CP022298.1|AZN63247.1|807521_809639_+|hypothetical-protein
MLDYDHPKELITPDDILNECTQLVSFNDAYSSHPLIQRFGSPEQPIYVDDGNVDINGVTYAQPLIMPIYDGQMELVQCAVMQDGQRVAVMPDGLARGFARYGDFDHAQPVIITYSLEAFFKVAQTGYAVALVLLPTLCNKHQTELKPYDFEQIQFVINQLSQAGYKQLYLPVRIEHINLEPFKKLEQNTAVRLLCQYLRIGVNQFEIGLSQDESVSEVLAFIEEAIELLSKPTDWGDLLPLSQSETVLNPYPIHALPPLAQEAVKAISEHVQSPIAMTAQCVIGAMSHIAQAKVNAPHPFNAHGEPCSLFLLTEGQSGSRKSTSRNLADQAIIKHERKQYEAYRQELEQWKSAQAGLPKKDREAYCAENPPPNDPSTLYSDITLESIAGLFIDGVLNNASIASDEAGQFFGGHSMKADTRNQALGGYAKLFDDGFVERTRSKSNLNGSGRAYDVRLTFNLQGQHEVLAEALKDPVLRGQGFLPRFILTIPENLAGTRLQDAIYRNKNASTDHRLIAYWTRCEYLLDDCPQVKAEHELHNGRYVLPMNEEAKEIDAAFYNMFEELQGKGKRYEYLQAFASRASQLARRLATVFAYFEGLQWIDAKTLKGACEVVKHSLNEWAMYADIEVKTETEAERLIKWIAKKCNEQKTDRIAYSNVQTSCPRPMQKNKNLLEMVVEQLIDSNHIKIESIGRTRYVVIHPCLVK
>CP022298.1|AZN63246.1|807127_807529_+|hypothetical-protein
MPNQINKTAQNFLENSQVIIESLEGTLLRLYVSYEQHDISDAKAKAMLSVCEMLASAALEDIESASAKTILDISMIVSRATGILYTLEELAHLNLAKGHTAAAINGLTLACSTLNELLETAVDYVMKGGSHNA
>CP022298.1|AZN63245.1|806823_807135_+|hypothetical-protein
MKNKSFNIANMPKYGYINRALGKISKLALVGYHQLAHTVRLKGFFCMCIFSMRSHVMAELEGEAFALASLLIDWSTNPFQLCHPHLVVNGKASKNQLGAHSHA
>CP022298.1|AZN63255.1|815833_816970_+|integrase
MSLTDVMCKKAQPQEKQYRLSDTNGLSLRIDPNGKKYWSIRYTENGQRKSKALGVYPELSLKRAREIALDLRYKLKNTVEVEEDQPCFKEVAEDWFNNQKETWSSKHISNVRASLDELYIALANKRINQIQAPEILQIIKKIEARGSLEVAKRTLSRCGMVMKYAIAHGYRYDNPAGDLVYALKNKRVKNLASLAATEMPEFLRRIKAYPADVQTHHAIILIMLTGVRVSELLQARWDEFDLEGRKWDIPEDRMKNRLPHRVPLTDMMIDELQALRLTHNQDLLFPHRLNNKEPMRSESILAVIKRSGYAGRMTTHGFRSLFSTVVNESNLFNPDAIERQLAHVPQNRIRSAYNRAQYWDERVKIMEWYGEHAKSWVS
>CP022298.1|AZN63256.1|817201_819805_+|hypothetical-protein
MKNITHDSKYKSTFFKQLKVLYEGERYSKFDSNEFFSVLPLISVYALLDFAVPYLIDNLEDGVCNLDQHLRFQSVASLLDALKQVHVFPEMSKFRNVGDEFLECRAFNCFVQRVQNGSVVIHSQNSQSLDNRVNGESHFADDGYAEVFLKKYIEWRGNKSTSCLLDARLNSSNVVLANLEQLKNKINPEIDSILDQTGFIYVAAFRVVIHSIDVDELHSNELLNVFQSFGQLDEIKHAMALSCSKLKESESYYVVCLLQKKYSPNENHIAQKIREVVQKEIDRSVSKRLQIDVHCLNEKFRALEPSMHDDTLFILKGNDDSSRLIRETVFDFAEHLLKFGQLSYVQVESKERREKLSDLELLSGLPNLLDRALPKHNSLKRTLPKHDLFWVKCNEFENYQSLWNLLQGSKGSKRFKLIWDQKHLSENSKEYFTQASMIVVEQLAIWGLSKFTDLVIKIEFFILTFMESSVIGFYPFVKDYRFKRWSDPVSFEQIATRQLIQFAEISKNRELLHELAVKLQGKFISKTLAHFFSVFRNQIGDSYSSGLLYRFLYIDLEAERNQEQIEDLLAVYQFKEVLFFHPQNNIKNNQSALPAKFEFKEETKGEQDVIKTYMNRSSTLSIGCNDSSNSLTIDGTPFQKYINTLPARPVEGQSSHLLHMQRHKTRLIKVKEMLRFAMRQDVVIIRCLFSEQSKDRITQQDLSKIFSNMLQINKKSLPFSFITGYLGYWEGIERTTTNKILGFAANVLFVFNAQVLTQCPDLLDALTEAWKKSCRNYGLEKRDSDCIDGVVEQLKLAYSVPELNCTQLILETTHKKLAKIFIHHVAPIAVYQDLLDDEIYQTLPKWLIKKNVKMSSSKTVKLRKTKT
>CP022298.1|AZN63257.1|820795_822015_+|IS3-family-transposase
MKKPNYTPEIRERAIQLLIESEKDYPSTWAAITAIAPKIGCTPETLRSWHQKYLNQQNPIKVQQLSDQERIKQLERENKELQRANEILRKAAGFFRPGGARPPTQIMVDFIHNNKELYGVEAICRILPIAPSTYYRTLDLADNPEHRAKRDLHDLHHAEQIKRIWKESSGRYGVRKVWQKLKREGYIIARCTVARLMQKLGIQGVWRGKNKQTTRSRDDQKRADDLVKRNFSADHPNQLWVGDFTYIQTHSGWVYTAFVIDVFSRAIVGWKVSTRMNTDMVLDALEQALHDRGMPKNVIHHSDRGVQYLSIRYTNRLEAANLRASVGTRGDSYDNALAETVNGLYKTEVIKYLKADWQGLADVQLATLNWVDWFNKTRVHSALGYVSPFEFEAMYYDKINPLGQVA
>CP022298.1|AZN63258.1|828903_830123_+|IS3-family-transposase
MKKPNYTPEIRERAVQLLIESEKDYPSTWAAITAIAPKIGCTPETLRSWHQKYLNQQNPIKVQQLSDQERIKQLERENKELQRANEILRKAAGFFRPGGARPPTQIMVDFIHNNKELYGVEAICRILPIAPSTYYRTLDLADNPEHRAKRDLHDLHHAEQIKRIWKESSGRYGVRKVWQKLKREGYIIARCTVARLMQKLGIQGVWRGKNKQTTRSRDDQKRADDLVKRNFSADHPNQLWVGDFTYIQTHSGWVYTAFVIDVFSRAIVGWKVSTRMNTDMVLDALEQALHDRGMPKNVIHHSDRGVQYLSIRYTNRLEAANLRASVGTRGDSYDNALAETVNGLYKTEVIEYLKADWQGLADVQLATLNWVDWFNKTRVHSALGYVSPFEFEAMYYDKINPLGQVA
>CP022298.1|AZN63259.1|830294_831439_-|IS3-family-transposase
MEYFMARRPRRNHSNDFKAKVALAAIKAEKTLAELSAEFDVHQNQIIDWKNQLISASSQAFDQSKAPTEPPIDLKKLHAKIGEQALEIGFFRRCVEETGPLQPQKLIDDSLQISVSKQAQLLKVSRGCYYYRPKPVSASDLKLMRCMDELHMQYPFAGSRMMRDLLNRQGHHIGRRHTRTLMKKMGINALYCKPNLSQANQAHRKYPYLLKGLAIQRSNQVWSTDITYIPMAKGFVYLCAVIDWHSRKVLAHRVSISMEVTFCIETLNEAIEKYGRPEIFNTDQGSQFTSDAFIDVLKSNDIQISMDGKGRWVDNVMVERLWRSVKYEEVYLKAYSNVLDAKKQLNAYFEFYNLKRPHSSLDKMTPDEFYYDQLPQQNKVA
>CP022298.1|AZN63260.1|832107_832419_+|hypothetical-protein
MSENNELELKPINDLLGLSFYIPAYQRGYRWTKRQVTELLDDIKEFQRNSEASSKEVFYCLQPIVVKKYKDSWELVDGQQRLTTIDLFHKSFFTQFQIIDPSN
>CP022298.1|AZN63261.1|832377_832848_-|IS5/IS1182-family-transposase
MPQKFQYKGLKKQKKSYSGKKKAHTFKVQAIVHYKTQQILSLCTSRGAVHDFELFKRNLNQIPASAFILADKGYQGIYTVYRNSLLPLKAKKRCKLDPELKLYNREINKRRIGIEHVFGSLKTFKILAERYRNRGKRLGLRFNLIAGIYNLELSKK
>CP022298.1|AZN63262.1|832789_833191_-|DDE-transposase-family-protein
MKYIYSKKLSETQFKRYTGISWSTFNLMVEQLKMHVPAKGRPSKLSLEDQILLCLSYWREYRTLFHVATSYGVSEPTASRIVHHVEDCLIKSNLFNLPKHLPEGEGIDWNVVIVDATEIPIQRPKKTEEKLQW
>CP022298.1|AZN63263.1|833245_834838_+|hypothetical-protein
MGRFLIYERDLIFIILTYLKGILDLLGKSRYQLSYETRENSAEFLNHIDENQGNQNIDFYHIVQAKKAIDEWFKKQEGTYQIKFIQTLLNDDDTGKNIKVIWYQIGESENATEVFTRLNMGKIPLVNAELVKALFLKSSNFTKEGKAAKHLQQLNIAQEWDVIEKRLQDDAFWYFISNKTTETNRIEFVLSLAARNLDGEGIIDSDKLKVFLQFNRLLSEKSADVVQEWLKIKQCYMTLEEWFNDRALFHVIGYLVSQDVAIDTLFDLSQTSKTKYTFRQSLINLVLKKSFGYQELNALPENWIDEALSTLTYDSGSKRLRSILLLFNIASLLSNPATNARFQFDKYKGDRWDIEHIRSVASEMPVQKEKQKAWLDNVISYISEDASFDIEGKKTEDNSKEQAIKKDAITLMDSTSFDNDQFEAIYMRVISHYDPRGDEDVDNSIGNLTLLDSSTNRSYKNAVFPIKRARIITLDKEATFVPLCTKNAFLKYYSKQVDKMLYWEPRDSQDHQRAMSEIILGFFCGKGVHQ
>CP022298.1|AZN63264.1|834834_837309_+|hypothetical-protein
MSKGNSLTFYGLFDIVDVIEIPILQRDYAQGRTEESEVRTLFLNSLFEALNLNENTARQTLDLDFVYGSFEDGNEKVFSVLDGQQRLTTLFLLHWYLAVENKCSQNFRDRFMTSDGRSRFTYKTRPSTTEFFNMLISTDIVLLKGRVSDHIRDAQWFYLSWQQDPTVQACMTMLDAIQIRFSGKSSKFYDRLINTSTPYITFQFLDLHSFGLSDELYIKMNARGKPLTIFENFKAKLEQKIKSFKTPWPIYNLPFKAGNIEAYEYFIHKIDTDWADLFWPYRNECSQDNTFDDELMNFFRLIIAYQYLLNNKKSEENLAEAKSNLFGSGGDLEATELSKYEELNCLNKDLIIRLINFLDLINNNGLTDNKIKKYLTERYYYSEEDTFKKVLANIAGYDDKLRFYAFYNYLSKLPISQELNEWVRVIYNLTQNTIINTVDEFYKALFAIDELCQFETPILVNLKKGIDISGFSSAQLLEEKIKAHLLLKSKEWREIIIQLEKHSFLDGQIGCILNFSGVLAFYREHEACDWDEMQDRHYREQFSKYAQSITAVFDLIKNSSSSIDFLWERAVLSKGIYFTEKSGAKYNLLSSRDTRNNIPRDHSWRRLLRINTSLIEQKQEYVKQVFDDPNFDAKDIIGSLKIICKDALSLLDANDWRILFVERPELFGVCEQGFIINNSNEFILLHQSQRNHTHSELYSKYLYLQLKAEHFNSEPFTIFKYVPTIGTDYFTHISLEGFHDDELHYEIHVWYESKQYHIVFFKIGTKPYPQSLIDILIQTDFIESPYEEYKDAYRYECFTPNNSKIKLIELCKTLSKFNKRMLTD

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Crispr_ID: CP022298_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022298_3

3040326-3040437

Orphan

Consensus_repeat	Method
TTGAAGATTTGAAGATTTGAAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP022298_3

>merge|CP022298|3|3040326-3040437|CRISPRCasFinder
TTGTATTTTTTAAGATTTGAAACTGGAATCTTAAGGCATTAAACAATTTTTAGCTAGTTGAAGATTTGAAGATTTGAAGATTTGAAGATTTGAAGATTTGAAGATTTGAAGA

>CP022298|3|3|3040326-3040437|CRISPRCasFinder
TTGTATTTTTTAAGATTTGAAAC	TGGAATCTTAAGGCATTAAACAATTT
TTAGCTAGTTGAAGATTTGAAGA	TTTGAAGATTTGAAGAT
TTGAAGATTTGAAGATTTGAAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP022298.1\|AZN65254.1\|3052674_3053358_+\|Fe2+-dependent-dioxygenase	unknown	unknown	gnl\|CDD\|235483
CP022298.1\|AZN65251.1\|3046093_3047425_-\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
CP022298.1\|AZN65240.1\|3033962_3036104_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|235537
CP022298.1\|AZN65253.1\|3050213_3052559_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227115
CP022298.1\|AZN65239.1\|3032689_3033907_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
CP022298.1\|AZN65246.1\|3040897_3042424_+\|fumarate-hydratase	unknown	unknown	gnl\|CDD\|377546
CP022298.1\|AZN65247.1\|3042527_3043076_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378261
CP022298.1\|AZN65245.1\|3039969_3040248_-\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN65244.1\|3039077_3039947_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP022298.1\|AZN65238.1\|3030812_3032078_+\|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|234685
CP022298.1\|AZN65249.1\|3043956_3045267_-\|ATP-dependent-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
CP022298.1\|AZN65241.1\|3036307_3037318_+\|hypothetical-protein	unknown	unknown	unknown
CP022298.1\|AZN65252.1\|3047698_3049882_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|227112
CP022298.1\|AZN65242.1\|3037373_3037883_-\|damage-inducible-protein-DinB	unknown	unknown	gnl\|CDD\|225200
CP022298.1\|AZN65248.1\|3043081_3043798_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378537
CP022298.1\|AZN65250.1\|3045295_3045901_-\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP022298.1\|AZN65237.1\|3029174_3030506_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP022298.1\|AZN65255.1\|3053407_3054514_+\|alpha-hydroxy-acid-oxidizing-enzyme	unknown	unknown	gnl\|CDD\|376451
CP022298.1\|AZN65243.1\|3037992_3038898_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
CP022298.1\|AZN65236.1\|3028234_3029110_+\|leucine-carboxyl-methyltransferase	unknown	unknown	gnl\|CDD\|225852

Protein	Function_ID	Function_description	E-value
CP022298.1\|AZN65254.1\|3052674_3053358_+\|Fe2+-dependent-dioxygenase	gnl\|CDD\|235483	PRK05467, PRK05467, Fe(II)-dependent oxygenase superfamily protein; Provisional.	1.12022e-146
CP022298.1\|AZN65251.1\|3046093_3047425_-\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	2.83742e-177
CP022298.1\|AZN65240.1\|3033962_3036104_+\|phosphate-acetyltransferase	gnl\|CDD\|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
CP022298.1\|AZN65253.1\|3050213_3052559_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227115	COG4774, Fiu, Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism].	0
CP022298.1\|AZN65239.1\|3032689_3033907_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
CP022298.1\|AZN65246.1\|3040897_3042424_+\|fumarate-hydratase	gnl\|CDD\|377546	pfam05681, Fumerase, Fumarate hydratase (Fumerase). This family consists of several bacterial fumarate hydratase proteins FumA and FumB. Fumarase, or fumarate hydratase (EC 4.2.1.2), is a component of the citric acid cycle. In facultative anaerobes such as Escherichia coli, fumarase also engages in the reductive pathway from oxaloacetate to succinate during anaerobic growth. Three fumarases, FumA, FumB, and FumC, have been reported in E. coli. fumA and fumB genes are homologous and encode products of identical sizes which form thermolabile dimers of Mr 120,000. FumA and FumB are class I enzymes and are members of the iron-dependent hydrolases, which include aconitase and malate hydratase. The active FumA contains a 4Fe-4S centre, and it can be inactivated upon oxidation to give a 3Fe-4S centre.	1.04189e-139
CP022298.1\|AZN65247.1\|3042527_3043076_+\|hypothetical-protein	gnl\|CDD\|378261	pfam09832, DUF2059, Uncharacterized protein conserved in bacteria (DUF2059). This domain, found in various prokaryotic proteins, has no known function.	4.76714e-05
CP022298.1\|AZN65244.1\|3039077_3039947_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	8.60659e-33
CP022298.1\|AZN65238.1\|3030812_3032078_+\|glutamate-5-semialdehyde-dehydrogenase	gnl\|CDD\|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
CP022298.1\|AZN65249.1\|3043956_3045267_-\|ATP-dependent-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
CP022298.1\|AZN65236.1\|3028234_3029110_+\|leucine-carboxyl-methyltransferase	gnl\|CDD\|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	7.52111e-16
CP022298.1\|AZN65252.1\|3047698_3049882_+\|TonB-dependent-receptor	gnl\|CDD\|227112	COG4771, FepA, Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism].	0
CP022298.1\|AZN65242.1\|3037373_3037883_-\|damage-inducible-protein-DinB	gnl\|CDD\|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	8.45167e-29
CP022298.1\|AZN65248.1\|3043081_3043798_-\|hypothetical-protein	gnl\|CDD\|378537	pfam11008, DUF2846, Protein of unknown function (DUF2846). Some members in this family of proteins with unknown function are annotated as lipoproteins however this cannot be confirmed.	1.38869e-22
CP022298.1\|AZN65250.1\|3045295_3045901_-\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	7.18326e-156
CP022298.1\|AZN65237.1\|3029174_3030506_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.27883e-10
CP022298.1\|AZN65255.1\|3053407_3054514_+\|alpha-hydroxy-acid-oxidizing-enzyme	gnl\|CDD\|376451	pfam01070, FMN_dh, FMN-dependent dehydrogenase.	3.85793e-146
CP022298.1\|AZN65243.1\|3037992_3038898_-\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	5.56071e-14

>CP022298.1|AZN65245.1|3039969_3040248_-|hypothetical-protein
MAQKHAGNVIVEDIFKFNFYCMMLAMSPLLLKKAPPKNDVEMTIFEEKQHMEMRHQVLSQSAQERRKAYLMSAFFGFLMSSLMMSFILMLDK
>CP022298.1|AZN65244.1|3039077_3039947_+|AraC-family-transcriptional-regulator
MKYQILDQLQQHKAQLLDSVELGSGMQLAMWQNNQDRVSVCSNHHTLSMYIQGGYHSYQKTAQGWHNGGGPDHMCLMPQDFESTWDLRDPLTFVHLYYTEQHLQRVAEQVWDREPSQIILNPQSFVADPQIAMIYRHFLLNGAWQNRENHLQMSTATTLLLNHLIKNYSHTEWQVPEVKGGLSPYTLKQLLEWIDQHIQQSLTLSDLAEQTQLSEYHFAHMFKQSMHMPPHQYVMQRRLELAHQALQHTSANMTDISEQYGFSSSSHFSHRFKKYFGYSPSQMRKSEKN
>CP022298.1|AZN65243.1|3037992_3038898_-|EamA-family-transporter
MNALLYALVVVIWGTTWIAISLQQQSGISTNVAVFWRFFISALVLFTFVVLCRKLQKLAVKDHLFCMLQACCIFGFNFVCFYYAVQYISSGLEAVIFSMAVIFNTLNAKLFFGQQVSTRFYPAALLGGLGIIALFWHDVVGSTLNNHTLMGIGLCVLGTYGFSLGNMISARHQKNGLDIFTTNAYGMLYGSILMALIAGFKQDEFFPAMEFSAVSALLYLAIFGSVIGFTAYFYLVGRIGAGKAAYSTLLFPLVALVISTIWEGYQWHMNAVIGVILILCGNAIFFIKPPKLKFSQMLKRS
>CP022298.1|AZN65242.1|3037373_3037883_-|damage-inducible-protein-DinB
MDLKMFELFARYNVWSTQKLNQVLKNVSDEDFNAECGLFFKSISGTLNHLLVGEHYLWFPRFSSKPSPTLKLNTIVERDKDKLMFELESRAYNWIDFLKHVDVEKFGHDLQYKTSAGQEMSLPYAATLLHVFNHGTHHRGQVTAALTSMGYPCPEIDMVYMLIEENLPV
>CP022298.1|AZN65241.1|3036307_3037318_+|hypothetical-protein
MNKKLLPILIVTTFSLTACNESKQHQTPSDSTTAYKNLSTANPADIKADLDALDQISNKNSQAILNVQDALKAARQNKEVDTIPALLEQLKTHSLAFNTALDATNFKSQEGAALREKFKQVHLLGVELAQEDTKNPPQMDRITGLEAQISVIQQSSVSEMRALQQMVYPQLNSGALDNTRQQPKPNTEPHVAARTAPQTTSHLSQDNAADIKHDLIALGAQSSAAKQEAENSIWEIKHAMEKKDLRALKTAIEKSNKRIQSLNQNYDMVSLKSSEVAAAREKLKKDNNLQIEMGEIILSTSPDKQKFEELQKKRSNSQKMVEIEMEALRIKANTAS
>CP022298.1|AZN65240.1|3033962_3036104_+|phosphate-acetyltransferase
MKTILLVPTGEGVGLTSACLGLVYALECQGVKAGFLKPFSQELTTGADRTTALYHHVSKNETVEPISYHTILQQLSAGENDELLEDAVRLHRAIARKHDLIIVEGLVPNSRDSFASELNAQLAQALDAKVIIVSNADINKPSATAEKVDSQLRYFGGASSERTAGVLLMRTKGLPDDSAHIPVTFDPSLRLISDTNKFIIELQKTHAKLGSDKLPVIGLVPFSNTLSVPRISDLASHIQAEWINQGDATQRRVLHSSLIASNIEHELHKFVAGELIISASDRIDVLLASSLASSNGIPLAGLVLTEHHTPNEQVLAFCQTAIKQGLPILHTALSTFDTAQSLANLSNEIPVDDTERAEQVTRFVSSHINEEWLTAMLNGSYQPRLSPSAFRHELVQKSIAAKKRIVLPEGDEPRTVQAAAICQSRGIAHCILLAKPEAVVEVAKARGIELPHDLEIIDPDLIRENYVEKMVELRKGKLNELQAREQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPEYSLVSSVFFMLLPDEVYVYGDCAINPDPNAEELAEIAIQSADSAKAFGLDPRIAMISYSTGTSGAGAEVEKVAEATRIAKERRPDLLIDGPLQYDAASVESVGRSKAPDSKVAGRANVFIFPDLNTGNTTYKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQATA
>CP022298.1|AZN65239.1|3032689_3033907_+|acetate-kinase
MSTSVLVINCGSSSIKYALVSERREDRIFGLAENLGSADARIKGITAGGQPLELSIPHADHEKALETILERLSHYNPQAIGHRVVHGGTLTKAELLTEEIVERIRAATPLAPLHNPAHLVGIDATMRLFPELPQVAVFDTAFHQTMPAHAYRYAVPKFLYTEHNVRRYGFHGTSHAYVSERGSELAGSFKQGGWLTAHLGNGSSTCAIWNGQSVDTSMGLTPLEGVVMGTRSGDVDPSLHSFLANNLGWDIYKIDKMLNSQSGLLGLSDLSNDMRTLIEASEQGNEDATLAIEVFCYRLAKSLAALSCGLPRLDGLFFTGGIGENSAYIREKTVAFLPHFGFNLSKEANDSLKRGTEGRIDTGTGPQIWVVPTDEEGRIAKETASVADEVIQTAAKKSEDNVAIA
>CP022298.1|AZN65238.1|3030812_3032078_+|glutamate-5-semialdehyde-dehydrogenase
MQESIEQYMQTVGQQARQASRILARASTETKNNALSAIYTALVNSEPTILAANQADMNKAHSNNLDSALLDRLELSPARFKGMLQGLKDVISLKDPVGEITDMAYRPSGIQLGKMRVPLGVVGMIYESRPNVTLEAASLALKSGNAIILRGGSEALESNKAIAEAIQRGLKLAGLPEHAVQVINTADRTAVGQLITLTEFVDVIVPRGGKGLIERISNEARVPVIKHLDGNCHVYVEAQADLQKALPIALNAKTHRYGVCNAMETLLVDEKVADEFLPRVAELYTEKQVELRGCAETQRILGTAVKTATEEDWYTEYLGPILAVKVVSGVEEAIEHINKYGSHHTDSIITENYSLAREFLAAVDSSSVMINASTRFADGFEYGLGAEIGISTDKIHARGPVGLEGLTSQKWIVFGDGQIRQ
>CP022298.1|AZN65237.1|3029174_3030506_-|alpha/beta-hydrolase
MNSMIQRDAELDDANLRLGFFDVYHRNSFKEPARTTWIEGWKVEYMAIARPESFHRTPIVIIGGAFQNFNSYKYCVEQLLDAGPIVLIDLPSMGANQQIRNIDTGLSAGTLELGDLAKMLGVWFDIEGLDKVSVMGMSLGSVVASCLADQRPELIDRMILMGVMQKTRKSWRMLLEESLHLMREQRMDEFGQAVILYLVNHAKMDKTKMSPTAKRLFFRQMAEFTATEQERYEINCNRLLRLTDVPIPQCKVLVACGQYDSFTLPHENANFALQCPDMEYAQIANADHVPQLQRRKETMHLFATFLKDESIQHLDGIIPFSRAQMLEMERRGEERVQIQQPETFLSYRHSDLVIATEVVDLNYFGVFLRFESDLAAVAAKYPRDLALHLSDEEGEFQIECLIFAEDGAYIRALFKHGSFELAERLLRFVGRQKQEQTLLEAVS
>CP022298.1|AZN65236.1|3028234_3029110_+|leucine-carboxyl-methyltransferase
MTDALSAHRHISFTAHYTGYIWYSMGISHPVFATRKGKLLAKLVHPLESWAEKHVGGSMRTTLKQRHQMIDDHLSALIQQYPTLQVLEIASGLSPRGWSFRQQYPEIDYRELDLPDMAQIKTQALKQIDQTSPVVLSADLFSADFARAFEVFDPNRPLVVVSEGLINYFSKDMLAQLLQGIVQYGQQFDQLYYLTDLYPEPVKNKLANFIWSSSKLLKWMSRSAFGFHFVSPPEATQFFKQAGFHTVTVHQPTLAFNSTQADTSNLDQQDHLGDLVWLVHSQWQKPNQPEQ
>CP022298.1|AZN65246.1|3040897_3042424_+|fumarate-hydratase
MTTIIKQDDLITSVKDALQFISYYHPQDFIQAMNRAYDREENKAAKDAIAQILINSRMCAEGHRPICQDTGIVNVFVEVGMDVKFDLTMSLDDAINEGVRQGYLENSNVLRASVLADPAFGRKNTKDNTPAVIYHKLVPGNKVDITVAAKGGGSENKSKLAMLNPSDSIVDWVLKTVPTMGAGWCPPGMLGIGIGGTAEKAMMLAKESLMEEINMDELLRRGPENKIEELRMEIFEKVNALGIGAQGLGGLTTVLDIKIKDYPCHAAGKPVGMIPNCAATRHAHFQLDGTGVAHIQAPKLEDYPSVTWDSSTSKRVDLDTITQEEMNAWQPGDTLLLNGTIYTGRDAAHKRMVDMLNNGEELPVDLKGKFIYYVGPVDPVGDEVVGPAGPTTATRMDKFTRQVLEATGMFGMIGKADRGPAAVEAIKDNKATYLMAVGGAAYLVSKAIREAEVVAFADLGMEAIYKFVVKDMPVSVAVDVNGTSIHATAPKIWQAKIGKIPVVDAAAG
>CP022298.1|AZN65247.1|3042527_3043076_+|hypothetical-protein
MKKLNHILCGITLCVLSTASFAKPATEASVEKALKLGDIKGTLAQSQQEMRPVYDQQAEEIIKNIFKTSTLNAEQQKAAKQIAEITASFSSKLISDPKFMQMLKNVYMQTFTEEEVLANIQFLETPLGQSINKKSSKMMSEIMRNSIAMSAEMMQDPAIQLEMNRQIEKTLAPLFEQAKKVQ
>CP022298.1|AZN65248.1|3043081_3043798_-|hypothetical-protein
MRAMTITLLSSLILLGCHGKATVEQPELISTLSHEVDFEHDPGMVEQYRIGVFSVGGWVNQKLGQRFQRVQPQHEQAAMVYLYRPDSKWNRQEIVASSLFINKERIPSLLNNHYYWVELPAGTYRLSSSRPLGINHFQKPKYIDFSVEAGQSYFIKYDEENLSTRRDVSGPLAVIPEKIAIQEIAFTQLKSNSYNFVAEDQHTGELRKKAQKLKPAKYDPSEDVQLMKPFKLWNPLTW
>CP022298.1|AZN65249.1|3043956_3045267_-|ATP-dependent-protease-ATP-binding-subunit-ClpX
MSEHPQGQKHCSFCGKTQSEVGKLIAGEDAYICNECVDVCLDLVQTSQQVESGDWAAKPLPKPHEIRAALDQYVIGQDVAKKTLSVAVYNHYKRLKATHGGHKHDDAVEIAKSNILLVGPTGSGKTLLAQTMARLLDVPFAMADATTLTEAGYVGEDVENIVQKLLQKADYDVEKAQKGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDTANILFICGGAFSGLEKIVQQRQEKGGIGFTAEVKKKDEGKKLSDLFRQVEATDLVKFGLIPEFIGRLPVIATLEELDEEALMQILTEPKNALTRQYQHLFDMENVDLVFEDSALRAVAKKALDRNTGARGLRSILENTLLETMYDLPSRTDVGTVVVNEDVINGTATPLFKPERLPRIEQKDAAKVDLKVINSKSA
>CP022298.1|AZN65250.1|3045295_3045901_-|ATP-dependent-Clp-protease-proteolytic-subunit
MYIPTIDNALVPMVVEQSSRGERSFDIYSRLLRERVIFMTGEVEDNMANLIVAQMLFLEAENPDKDIHLYINSPGGSVTAGMAIYDTMQFIKPDVVTYCMGQAASMGAFLLNAGAKGKRYCLENARVMIHQPLGGFRGQASDIEIHAREILFIKERLNRLMAEHSGQDYETVARDTDRDNFMTAQAAKEYGLVDEVLSKRP
>CP022298.1|AZN65251.1|3046093_3047425_-|trigger-factor
MQVTSEAVSGVTRRLNVSVPTSRVNEQFEARLKRTAKTVKINGFRPGKVPVNVVRREYGAGIYQEVVSDIIRDTVFEAIQQEKINAVGMPNIEKSELKDDALVYEATVEVYPEVNVKFDGLEVERKASEVNDKDVDQMIENLQKQRASWAETKGMAKKDMQVTFDFEGSVDGEKFEGGSAEDFKLVLGSGRMIPGFEDGIVGMKKGEEKVIDVTFPEDYQAENLAGKSAQFKITVKLVEKQKLPEVDAEFLKIFGLTEEEGIEKLKADVRKNMEREVKNGLRNQVKGAAFDALVAANEVELPASMVAQEVDRQRQQMIQQFTQQFGAQGAKAFDSSMLPDELFKEQAEKSVKLGVLVSKVLADAKIEVDQARVDAYIEDMASSYEDPAEVIEYFKNDKQQRSQIEAVVLEDQVVDHILASAKVTDTAVSYEDLLKEQQARQQG
>CP022298.1|AZN65252.1|3047698_3049882_+|TonB-dependent-receptor
MSKFNLHPLSLALLGAITTPVFAETTTEDSSTHQLSTIVVSAAGFEQDIKKAPATMTVITAEDLKNKRINSIADALSDIEGVDISPTAGKTGGLNIRIRGMDSEYTLVLIDGRRQNSTGDITPNGFGESNNSFIPPISAIERIEVIRGPASTLYGSDAIGGVVNIITKKVSNEWTGAVTLEGTLLPNSSDFGNQRSVDAYVTGPLIPNLLGIQLRGRKAERDQSNVIRSDDEGTETKLTQGQNPTKSDLENIGVRLTLTPTDQHDISAEYEQTDQWYDNSKGQLGTLGANGGYDKSQEYNREKMILSHTWRSNIGTLESSLANTQTETVGRLIPARAQNMSQAITPRLLESEDTIFDTKFTTNYINGHNITLGGQWWDASIRDGLRVQKEVSFEQLGLFAEDTWSLNDSLALTLGLRYDNHDTFGDFWTPRAYLVWNANENWTFKGGYSEGYKAPRLERLTTGIYNVSGQGRTPVFGNPDLKPETSKNLELGTYFTNNSNFDFNITGFFSEIEDKIMTGNAELRCNTDTNKQQCEDYMLSVGTPWTMDYNRGAPDTWNVTRPINAEEAEVYGIETGLNWEFAENWKLGLNYTWTETEIKDKQLNNPVLNDTPKHMANASLKWQAADFVNLWARGEYRSERARFTSNYENLTAANQAVYDALGDYKAYTLFHIGSNFIVNDNWDVGVALYNVFDKDFNDYEKIGTGYYNRYSNTQEGRRVQLSTTFKF
>CP022298.1|AZN65253.1|3050213_3052559_+|TonB-dependent-siderophore-receptor
MAFIKTRKKLVSSAIASTLSVVAVNAVAQDQIAQLETIHTEAAAEQSLKVDKSANSKFVAPLLNTPKSVSVISKQLIEDTQVTTLSDALRTVPGITLGAGEGGNPNGDRPFIRGYNSESSMYVDGVRNSTSQNREMFAIEQVEITKGSASAMGGAGTTGGSINMISKVAKKGDFLEGSVGAGTDDYQRITLDGNKDFGNGIAARVAVMGHHNDKAGQEDGTEYARAGIAPSITFGLDSDTRATLSYYYLKTDDTPDSGIPYNNPFGAPRTGAIDYRPLNGNGKPIDVKQGTYYGWKDRDFQKQENQSGTIKLEHDLTDNLTLSNTAVYNKSKNDYLWTNPDDSQGNFYNKPEFTNQLVGNVWARANSRVADTDTFTDQLALTGKFNTGRLKHNFNLGAEYSDQETDRTQYIIDGLTTTGAANSSCNAAAIASGWCTSVQNPNRGQWTGTISTEGADRYNIENENTSVYFLDSIEFSPQWILDLGLRWDDYSAKQTMTYGARNSAVLGSSTTPPTAKAGDKVAIKNDSDFINYQVGLVYKPAENGSIYASYATSSNPVGVDGGDGSEGITAAIQNLKPEEVKTYEIGTKWDVLNEKLNLTAAIFRTEKTNTRATTDEGTTQNIGETRVDGIELGVNGNITDKWAVSAGYTYLDSELIDGGFENIGTTAAPIYAPNSNNGKQVQNVAKNSATLWTTYQVMPQLTLGAGAIAMDKVYANAANTKWVPGYVRYDAMARYNVNKNVDLQLNVNNLADTRYFTKAYASHYATEAEGRSAVLSLNFKY
>CP022298.1|AZN65254.1|3052674_3053358_+|Fe2+-dependent-dioxygenase
MIHHIPNVLSKEQVQYFRNEMAKVEWIDGKKTTGSLSKNVKQNQQLPEDHPLTQHLGNIILEALGQHPLFMSAALPLDILPPYFNRYEQGETFGFHVDNAIRWVAGSKDRIRTDVSCTVFLSEPDEYEGGDLVVEDTYGYHEVKLPAGDMILYPSTSVHEVTPVTSGCRVASFFWVQSMIRDDADRHILFNLDQTIQNLRVQLGDQHQEVVKLTSLYHNLMRKWAEL
>CP022298.1|AZN65255.1|3053407_3054514_+|alpha-hydroxy-acid-oxidizing-enzyme
MTSKTVLPPLTQIPASLQTIADYEIEAEKHLPEMVWHYLQGGAMDEISVRNNLAQFQNLHLIPRMLRDLTQGNTSCEILGQTFPHPIFVAPIGHQQQFHPEAEAATALAAEVLGSNMILSTFTNTDMRTFKPENPYKWFQLYWQGDRDKSLALLKLAEAQNFTAIVITVDSPHTGVRDRERRAFFHLPENMQHPHTPAHIPLPELQEGDHPVFNGLMKIAPTWDDIAWMVQQTDLPILLKGIVSPLDAHLAIQQGVQGLILSNHGGRVLDTCIPPLKALQLIKKAVPHDFPLLYDGGVRRGSDVFKAIALGASAVLVGRPCIYGLATAGALGVAHVLKILKEEFEITMALMGAATLADIQPDMVIEFS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP022298_3	3.2\|3040398\|17\|CP022298\|CRISPRCasFinder	3040398-3040414	17	CP022298.1	3040422-3040438	0	1.0
CP022298_3	3.2\|3040398\|17\|CP022298\|CRISPRCasFinder	3040398-3040414	17	CP022298.1	3040430-3040446	0	1.0

1. spacer 3.2|3040398|17|CP022298|CRISPRCasFinder matches to position: 3040422-3040438, mismatch: 0, identity: 1.0

tttgaagatttgaagat	CRISPR spacer
tttgaagatttgaagat	Protospacer
*****************

2. spacer 3.2|3040398|17|CP022298|CRISPRCasFinder matches to position: 3040430-3040446, mismatch: 0, identity: 1.0

tttgaagatttgaagat	CRISPR spacer
tttgaagatttgaagat	Protospacer
*****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24301 : 78891

Helicobacter_phage(15.38%)

transposase,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN62539.1\|24301_24715_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	1.4e-46	60.9
AZN62540.1\|24735_25794_+\|transposase	transposase	A0A0H3UZC2	Geobacillus_virus	2.0e-25	35.0
AZN62541.1\|25866_26436_+	peptidylprolyl isomerase A	NA	NA	NA	NA
AZN62542.1\|32643_34002_+	aromatic acid/H+ symport family MFS transporter	NA	NA	NA	NA
AZN62543.1\|34600_35641_+\|transposase	IS481 family transposase	A0A077SLK2	Escherichia_phage	1.8e-175	83.8
AZN62544.1\|36654_38133_+	sodium-dependent transporter	NA	NA	NA	NA
AZN62545.1\|38142_38286_+	putative methionine/alanine importer small subunit	NA	NA	NA	NA
AZN62546.1\|38725_39106_+	hypothetical protein	NA	NA	NA	NA
AZN62547.1\|39278_39695_+	hypothetical protein	NA	NA	NA	NA
AZN62548.1\|41198_42503_-	16S rRNA (cytosine(967)-C(5))-methyltransferase	NA	NA	NA	NA
AZN62549.1\|42502_43462_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	4.5e-08	37.4
AZN62550.1\|43933_45763_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
AZN62551.1\|46199_47885_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
AZN62552.1\|47956_49255_+	hypothetical protein	NA	NA	NA	NA
AZN62553.1\|49385_51491_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
AZN62554.1\|51652_52390_+	anion permease	NA	NA	NA	NA
AZN62555.1\|52386_53292_-	transcriptional regulator	NA	NA	NA	NA
AZN62556.1\|53452_54754_-	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	2.1e-149	63.1
AZN62557.1\|55055_57740_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
AZN62558.1\|57945_58566_-	TetR family transcriptional regulator	NA	NA	NA	NA
AZN62559.1\|58629_59773_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN62560.1\|60006_61107_+	efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
AZN62561.1\|61109_64247_+	multidrug transporter AcrB	NA	NA	NA	NA
AZN62562.1\|64378_64756_+	hypothetical protein	NA	NA	NA	NA
AZN62563.1\|64860_65979_+	molecular chaperone DnaJ	A0A0P0YNN4	Yellowstone_lake_phycodnavirus	1.9e-26	34.6
AZN62564.1\|66042_66282_-	hypothetical protein	NA	NA	NA	NA
AZN62565.1\|66479_67301_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
AZN62566.1\|67360_68008_+	hypothetical protein	NA	NA	NA	NA
AZN62567.1\|68057_68459_-	hypothetical protein	NA	NA	NA	NA
AZN62568.1\|70038_71061_-	alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.7e-45	30.1
AZN62569.1\|71097_71652_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
AZN62570.1\|71671_71917_-	hypothetical protein	NA	NA	NA	NA
AZN62571.1\|71932_72487_-	peptidase M23	A0A223FZJ1	Rhodococcus_phage	1.1e-09	33.8
AZN62572.1\|72559_73594_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
AZN62573.1\|73702_74065_-	HIT family protein	NA	NA	NA	NA
AZN62574.1\|74139_74880_-	dienelactone hydrolase	NA	NA	NA	NA
AZN62575.1\|75047_75206_-	DUF1328 domain-containing protein	A0A0R6PJ30	Moraxella_phage	3.4e-06	59.6
AZN62576.1\|75408_75861_+	YcgN family cysteine cluster protein	NA	NA	NA	NA
AZN62577.1\|75960_77238_+	AAA family ATPase	G3MBE0	Bacillus_virus	3.1e-81	40.1
AZN62578.1\|77398_77812_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	1.4e-46	60.9
AZN62579.1\|77832_78891_+\|transposase	transposase	A0A0H3UZC2	Geobacillus_virus	2.0e-25	35.0

DBSCAN-SWA_2

189412 : 218869

Escherichia_phage(28.57%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN62682.1\|189412_191380_+\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	3.0e-22	25.6
AZN62683.1\|191431_192316_-	putative porin	NA	NA	NA	NA
AZN62684.1\|194918_196063_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN62685.1\|196139_196397_+	hypothetical protein	NA	NA	NA	NA
AZN62686.1\|196527_197019_-	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
AZN62687.1\|197156_199988_-	excinuclease ABC subunit A	A0A1B1IVR3	uncultured_Mediterranean_phage	5.2e-312	56.0
AZN62688.1\|200307_200682_-	hypothetical protein	NA	NA	NA	NA
AZN62689.1\|200844_201519_-	thiaminase II	NA	NA	NA	NA
AZN62690.1\|201730_202810_+	DUF475 domain-containing protein	A0A172Q0Y5	Acinetobacter_phage	1.1e-90	53.3
AZN62691.1\|202969_204334_+	MFS transporter	NA	NA	NA	NA
AZN62692.1\|204385_204970_+	single-stranded DNA-binding protein	M4SRQ0	Psychrobacter_phage	5.3e-36	65.5
AZN62693.1\|206586_206970_+\|transposase	transposase	NA	NA	NA	NA
AZN62694.1\|206912_207302_+\|transposase	transposase	NA	NA	NA	NA
AZN62695.1\|207376_208981_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	1.9e-144	54.5
AZN62696.1\|209252_210143_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZN62697.1\|211494_211692_+	hypothetical protein	NA	NA	NA	NA
AZN62698.1\|212121_213114_+	hypothetical protein	NA	NA	NA	NA
AZN62699.1\|213150_214197_+	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase	NA	NA	NA	NA
AZN62700.1\|214278_214773_+	flavin reductase	NA	NA	NA	NA
AZN62701.1\|215051_215615_+	peroxiredoxin	NA	NA	NA	NA
AZN62702.1\|216403_217285_+	pirin family protein	NA	NA	NA	NA
AZN62703.1\|217650_218869_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.4e-78	53.2

DBSCAN-SWA_3

231827 : 288946

Escherichia_phage(33.33%)

transposase,integrase

attL 231752:231811|attR 279639:280920

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
231752:231811	attL	NA	NA	NA	NA
AZN62715.1\|231827_232971_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN62716.1\|233274_233595_+	hypothetical protein	NA	NA	NA	NA
AZN62717.1\|233659_234706_+	hypothetical protein	A0A0H4INH5	Stenotrophomonas_phage	2.0e-57	36.8
AZN62718.1\|234855_235896_+	YqaJ-like viral recombinase	S6C475	Thermus_phage	8.3e-40	37.2
AZN62719.1\|236107_237004_+	hydrolase or metal-binding protein	NA	NA	NA	NA
AZN62720.1\|237083_237314_+	AlpA family transcriptional regulator	NA	NA	NA	NA
AZN62721.1\|237476_239030_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.1e-101	41.9
AZN62722.1\|239026_240241_+	restriction endonuclease	A0A2H4PQP5	Staphylococcus_phage	6.7e-33	31.4
AZN62723.1\|240242_241424_+	anticodon nuclease	NA	NA	NA	NA
AZN62724.1\|241416_244515_+	DEAD/DEAH box helicase	NA	NA	NA	NA
AZN62725.1\|245568_246765_-\|integrase	integrase	B7SYF8	Stenotrophomonas_phage	1.5e-77	41.5
AZN62726.1\|247158_249039_+	potassium transporter Kup	A7K9V6	Acanthocystis_turfacea_chlorella_virus	1.8e-72	33.6
AZN62727.1\|249098_249671_-	hypothetical protein	NA	NA	NA	NA
AZN62728.1\|250368_252030_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	5.5e-171	55.1
AZN62729.1\|254060_254450_-\|transposase	transposase	NA	NA	NA	NA
AZN62730.1\|254392_254776_-\|transposase	transposase	NA	NA	NA	NA
AZN62731.1\|255266_256295_+	hypothetical protein	NA	NA	NA	NA
AZN62732.1\|256351_257311_+	endonuclease	NA	NA	NA	NA
AZN62733.1\|257386_257674_-	hypothetical protein	NA	NA	NA	NA
AZN62734.1\|257740_258829_-\|transposase	IS3 family transposase	NA	NA	NA	NA
AZN62735.1\|258825_259188_-	hypothetical protein	NA	NA	NA	NA
AZN65750.1\|259280_259454_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
AZN62736.1\|259680_260900_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	5.8e-77	51.9
AZN62737.1\|261133_261526_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
AZN62738.1\|261616_262897_+	cation transporter	NA	NA	NA	NA
AZN62739.1\|262908_263169_+	ferrous iron transport protein A	NA	NA	NA	NA
AZN62740.1\|263158_264988_+	ferrous iron transporter B	NA	NA	NA	NA
AZN62741.1\|265831_267460_-	iron ABC transporter permease	NA	NA	NA	NA
AZN62742.1\|267541_268558_-	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
AZN62743.1\|268579_269704_-	Fe3+/spermidine/putrescine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-29	34.9
AZN62744.1\|270429_270717_+	hypothetical protein	NA	NA	NA	NA
AZN62745.1\|270703_271018_+	toxin-antitoxin system, antitoxin component	NA	NA	NA	NA
AZN62746.1\|271082_271709_-	hypothetical protein	NA	NA	NA	NA
AZN62747.1\|271695_272160_-	hypothetical protein	NA	NA	NA	NA
AZN62748.1\|272609_273828_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	2.2e-76	51.2
AZN62749.1\|273929_274970_-\|transposase	IS481 family transposase	A0A077SLK2	Escherichia_phage	1.8e-175	83.8
AZN62750.1\|275625_276791_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.5e-164	99.3
AZN62751.1\|277033_278252_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	3.4e-77	52.2
AZN62752.1\|278477_279622_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN62753.1\|279780_280074_-	plasmid stabilization system protein	NA	NA	NA	NA
AZN62754.1\|280063_280309_-	type II toxin-antitoxin system antitoxin, RelB/DinJ family	NA	NA	NA	NA
AZN62755.1\|280515_281463_-	histidine kinase	A0A127AWB9	Bacillus_phage	1.0e-12	28.8
279639:280920	attR	NA	NA	NA	NA
AZN62756.1\|281644_283165_-	catalase	A0A2K9L0T1	Tupanvirus	1.3e-94	44.9
AZN62757.1\|283863_285198_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
AZN62758.1\|285295_285616_-	hypothetical protein	NA	NA	NA	NA
AZN62759.1\|285650_285965_-	transcriptional regulator	NA	NA	NA	NA
AZN62760.1\|286284_287922_-	hypothetical protein	NA	NA	NA	NA
AZN62761.1\|288379_288946_+\|transposase	transposase	M9Q1K0	Clostridium_phage	6.8e-28	39.9

DBSCAN-SWA_4

761851 : 832848

Escherichia_phage(21.43%)

transposase,integrase,tRNA

attL 792831:792848|attR 818788:818805

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN63203.1\|761851_762583_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AZN63204.1\|762669_763623_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	2.8e-58	41.9
AZN63205.1\|763918_767011_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	1.5e-76	46.9
AZN63206.1\|767068_767974_+	transporter	NA	NA	NA	NA
AZN63207.1\|768038_768326_-	hypothetical protein	NA	NA	NA	NA
AZN63208.1\|768447_768720_-	cell division topological specificity factor MinE	NA	NA	NA	NA
AZN63209.1\|768722_769535_-	septum site-determining protein MinD	NA	NA	NA	NA
AZN63210.1\|769604_770336_-	septum site-determining protein MinC	NA	NA	NA	NA
AZN63211.1\|770459_771506_-	preprotein translocase subunit SecA	NA	NA	NA	NA
AZN63212.1\|771519_772452_-	acyltransferase	NA	NA	NA	NA
AZN63213.1\|772709_773360_+	hypothetical protein	NA	NA	NA	NA
AZN63214.1\|773486_775526_+	ATP-dependent DNA helicase Rep	A7KV33	Bacillus_phage	3.3e-109	38.0
AZN63215.1\|775569_776022_+	deoxyuridine 5'-triphosphate nucleotidohydrolase	G0YQD9	Erwinia_phage	2.6e-46	62.2
AZN63216.1\|776218_777646_+	phosphomannomutase	NA	NA	NA	NA
AZN63217.1\|777656_778559_+	acetylglutamate kinase	NA	NA	NA	NA
AZN63218.1\|778727_779576_+	class II glutamine amidotransferase	NA	NA	NA	NA
AZN63219.1\|779850_780306_+	hemerythrin	NA	NA	NA	NA
AZN63220.1\|780448_781531_+	hypothetical protein	NA	NA	NA	NA
AZN63221.1\|781530_781854_+	RnfH family protein	NA	NA	NA	NA
AZN63222.1\|781900_782299_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
AZN63223.1\|782411_782849_+	transcriptional repressor	NA	NA	NA	NA
AZN63224.1\|782908_784030_-	type IV pili twitching motility protein PilT	NA	NA	NA	NA
AZN63225.1\|784056_785094_-	twitching motility protein PilT	NA	NA	NA	NA
AZN63226.1\|785216_785906_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
AZN63227.1\|786089_786824_+	hypothetical protein	NA	NA	NA	NA
AZN63228.1\|786939_790536_-	ATP-dependent dsDNA exonuclease	NA	NA	NA	NA
AZN63229.1\|790545_791799_-	exonuclease sbcCD subunit D	NA	NA	NA	NA
AZN63230.1\|792195_793173_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
792831:792848	attL	NA	NA	NA	NA
AZN63231.1\|793507_793954_+	hypothetical protein	NA	NA	NA	NA
AZN63232.1\|794013_794934_+	TIGR01777 family protein	Q58M85	Prochlorococcus_phage	3.9e-09	29.4
AZN63233.1\|794941_796051_-	glycine oxidase ThiO	NA	NA	NA	NA
AZN63234.1\|796077_797091_-	delta-aminolevulinic acid dehydratase	NA	NA	NA	NA
AZN63235.1\|797199_797697_+	hypothetical protein	NA	NA	NA	NA
AZN63236.1\|797944_799096_+	EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
AZN63237.1\|799102_800632_+	MFS transporter	NA	NA	NA	NA
AZN63238.1\|800728_802213_-	glycerol kinase	NA	NA	NA	NA
AZN63239.1\|802881_804111_+\|integrase	integrase	A0A2H4JAT5	uncultured_Caudovirales_phage	3.3e-72	39.5
AZN63240.1\|804258_805371_+	hypothetical protein	NA	NA	NA	NA
AZN63241.1\|805506_805722_+	transcriptional regulator	NA	NA	NA	NA
AZN63242.1\|805725_805944_+	DNA-binding protein	NA	NA	NA	NA
AZN63243.1\|805946_806453_+	hypothetical protein	A0A0R6PGW1	Moraxella_phage	4.3e-26	58.8
AZN63244.1\|806445_806814_+	hypothetical protein	NA	NA	NA	NA
AZN63245.1\|806823_807135_+	hypothetical protein	NA	NA	NA	NA
AZN63246.1\|807127_807529_+	hypothetical protein	NA	NA	NA	NA
AZN63247.1\|807521_809639_+	hypothetical protein	NA	NA	NA	NA
AZN63248.1\|809941_810454_+	hypothetical protein	NA	NA	NA	NA
AZN63249.1\|810490_810817_+	single-stranded DNA-binding protein	M4SRQ0	Psychrobacter_phage	4.1e-30	54.6
AZN63250.1\|810935_811982_+	(p)ppGpp synthetase	A0A1B0VBT5	Salmonella_phage	6.6e-29	30.8
AZN63251.1\|812267_812636_-	hypothetical protein	NA	NA	NA	NA
AZN63252.1\|812717_813383_-	DNA transfer protein p32	A0A2I7RHN0	Vibrio_phage	7.7e-15	40.2
AZN63253.1\|813939_814128_-	hypothetical protein	NA	NA	NA	NA
AZN63254.1\|814124_814418_-	hypothetical protein	NA	NA	NA	NA
AZN63255.1\|815833_816970_+\|integrase	integrase	A0A2H4J339	uncultured_Caudovirales_phage	6.2e-73	39.5
AZN63256.1\|817201_819805_+	hypothetical protein	NA	NA	NA	NA
818788:818805	attR	NA	NA	NA	NA
AZN63257.1\|820795_822014_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-77	51.9
AZN63258.1\|828903_830122_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	5.8e-77	51.9
AZN63259.1\|830294_831439_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN63260.1\|832107_832419_+	hypothetical protein	NA	NA	NA	NA
AZN63261.1\|832377_832848_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1035223 : 1106375

Klosneuvirus(14.29%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN63436.1\|1035223_1035970_+\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.1e-12	34.2
AZN63437.1\|1037389_1037851_+	DUF2750 domain-containing protein	NA	NA	NA	NA
AZN63438.1\|1037868_1038648_-	hypothetical protein	NA	NA	NA	NA
AZN63439.1\|1038742_1041427_-	hypothetical protein	NA	NA	NA	NA
AZN63440.1\|1041598_1042159_-	hypothetical protein	NA	NA	NA	NA
AZN63441.1\|1042244_1044419_-	TIGR01666 family membrane protein	NA	NA	NA	NA
AZN63442.1\|1044560_1045760_+	Bcr/CflA family drug resistance efflux transporter	S4TR35	Salmonella_phage	1.2e-26	27.0
AZN63443.1\|1046871_1048152_+	DcaP-like protein	NA	NA	NA	NA
AZN63444.1\|1048659_1049901_+	sodium/glutamate symporter	NA	NA	NA	NA
AZN63445.1\|1049975_1051451_+	alanine:cation symporter family protein	NA	NA	NA	NA
AZN63446.1\|1051504_1052692_-	chromate transporter	NA	NA	NA	NA
AZN63447.1\|1052830_1053829_+	alpha/beta hydrolase	A0A1V0SKV5	Klosneuvirus	6.2e-08	26.5
AZN63448.1\|1054953_1055475_+	acyl-CoA thioesterase	NA	NA	NA	NA
AZN63449.1\|1055720_1055924_-	hypothetical protein	NA	NA	NA	NA
AZN63450.1\|1056414_1057404_+	cobalamin biosynthesis protein CobW	NA	NA	NA	NA
AZN63451.1\|1057472_1058003_+	hypothetical protein	NA	NA	NA	NA
AZN63452.1\|1058052_1058391_+	peptidylprolyl isomerase	NA	NA	NA	NA
AZN63453.1\|1058516_1060391_+	histidine kinase	NA	NA	NA	NA
AZN63454.1\|1060423_1060870_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AZN63455.1\|1061060_1062280_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	3.4e-77	52.2
AZN63456.1\|1062477_1062996_+	hypothetical protein	NA	NA	NA	NA
AZN63457.1\|1063005_1063590_-	TetR family transcriptional regulator	NA	NA	NA	NA
AZN63458.1\|1063596_1064505_-	alpha/beta hydrolase	NA	NA	NA	NA
AZN63459.1\|1064558_1065356_-	enoyl-CoA hydratase	NA	NA	NA	NA
AZN63460.1\|1065553_1066129_+	nicotinamide mononucleotide transporter PnuC	K4FAY9	Cronobacter_phage	6.7e-07	26.6
AZN63461.1\|1066137_1066407_+	hypothetical protein	NA	NA	NA	NA
AZN63462.1\|1066541_1067051_+	hypothetical protein	NA	NA	NA	NA
AZN63463.1\|1067121_1068399_-	MFS transporter	NA	NA	NA	NA
AZN63464.1\|1068612_1069098_+	peptide deformylase	E3SLL2	Synechococcus_phage	3.4e-20	45.3
AZN63465.1\|1069112_1069895_-	AraC family transcriptional regulator	NA	NA	NA	NA
AZN63466.1\|1070111_1071044_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	4.6e-58	40.9
AZN63467.1\|1071202_1071526_+	hypothetical protein	NA	NA	NA	NA
AZN63468.1\|1071562_1075249_-	methionine synthase	A0A140XBC7	Dickeya_phage	4.3e-14	60.0
AZN63469.1\|1075676_1077296_+	anion permease	NA	NA	NA	NA
AZN63470.1\|1077380_1078928_-	hypothetical protein	NA	NA	NA	NA
AZN63471.1\|1079072_1079240_-	hypothetical protein	NA	NA	NA	NA
AZN63472.1\|1079369_1079987_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AZN63473.1\|1080147_1080786_+	Fe-S biogenesis protein NfuA	NA	NA	NA	NA
AZN63474.1\|1080960_1083018_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	8.2e-15	30.6
AZN63475.1\|1083072_1084074_-	hypothetical protein	NA	NA	NA	NA
AZN63476.1\|1084089_1085121_-	alpha/beta hydrolase	NA	NA	NA	NA
AZN63477.1\|1085431_1086046_+	carbonic anhydrase	NA	NA	NA	NA
AZN63478.1\|1086076_1086718_-	arylesterase	NA	NA	NA	NA
AZN63479.1\|1086729_1087458_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-34	37.3
AZN63480.1\|1087459_1089949_+	ABC transporter permease	NA	NA	NA	NA
AZN63481.1\|1089979_1090795_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AZN63482.1\|1090872_1091547_+	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
AZN63483.1\|1091656_1093741_+	polyphosphate kinase 1	NA	NA	NA	NA
AZN63484.1\|1093828_1094731_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZN63485.1\|1094744_1095683_-	alpha/beta hydrolase	NA	NA	NA	NA
AZN63486.1\|1095740_1096919_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
AZN63487.1\|1096987_1097152_-	rubredoxin	NA	NA	NA	NA
AZN63488.1\|1097667_1098210_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.1e-19	36.3
AZN63489.1\|1098245_1098752_-	esterase	NA	NA	NA	NA
AZN63490.1\|1099029_1100556_+\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	1.9e-88	37.7
AZN63491.1\|1100695_1102141_+	hypothetical protein	NA	NA	NA	NA
AZN63492.1\|1102611_1103526_+	sulfate adenylyltransferase small subunit	NA	NA	NA	NA
AZN63493.1\|1103665_1105282_+	sulfate adenylyltransferase	A0A1V0SGC3	Hokovirus	4.6e-45	28.9
AZN63494.1\|1105442_1106375_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	4.6e-58	40.9

DBSCAN-SWA_6

1332068 : 1462525

120

Escherichia_phage(12.9%)

transposase,head,tail,tRNA,integrase,protease

attL 1374281:1374295|attR 1404446:1404460

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN63701.1\|1332068_1333448_+\|protease	serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	3.8e-24	29.9
AZN63702.1\|1333545_1334847_+\|transposase	DDE transposase	NA	NA	NA	NA
AZN63703.1\|1334959_1335436_+	thioesterase	NA	NA	NA	NA
AZN63704.1\|1335581_1337399_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	3.0e-21	25.1
AZN63705.1\|1337419_1338247_+	S26 family signal peptidase	NA	NA	NA	NA
AZN63706.1\|1338268_1338643_+	DUF4845 domain-containing protein	NA	NA	NA	NA
AZN63707.1\|1338614_1339307_+	ribonuclease III	M1H9B8	Acanthocystis_turfacea_Chlorella_virus	1.5e-21	37.4
AZN63708.1\|1339313_1340342_+	GTPase Era	NA	NA	NA	NA
AZN63709.1\|1340377_1340575_+	hypothetical protein	NA	NA	NA	NA
AZN63710.1\|1340585_1341296_+	DNA repair protein RecO	NA	NA	NA	NA
AZN63711.1\|1341309_1342035_+	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
AZN63712.1\|1342059_1342713_+\|tRNA	tRNA-(ms[2]io[6]A)-hydroxylase	NA	NA	NA	NA
AZN63713.1\|1343777_1344236_+	hypothetical protein	NA	NA	NA	NA
AZN63714.1\|1344305_1344740_-	phenylacetic acid degradation protein	NA	NA	NA	NA
AZN63715.1\|1345080_1345503_+	S-(hydroxymethyl)glutathione synthase	NA	NA	NA	NA
AZN63716.1\|1345631_1346501_+	EamA family transporter	NA	NA	NA	NA
AZN63717.1\|1346603_1347830_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AZN63718.1\|1348047_1348227_+	hypothetical protein	NA	NA	NA	NA
AZN63719.1\|1348269_1349736_-	histidine kinase	NA	NA	NA	NA
AZN63720.1\|1349942_1350476_-	hypothetical protein	NA	NA	NA	NA
AZN63721.1\|1350450_1350699_-	hypothetical protein	NA	NA	NA	NA
AZN63722.1\|1350903_1351695_-	hypothetical protein	A0A127KNK1	Pseudomonas_phage	1.3e-24	48.2
AZN63723.1\|1351870_1353892_+	excinuclease ABC subunit B	NA	NA	NA	NA
AZN63724.1\|1353995_1354580_+	hypothetical protein	A0A2K9L662	Tupanvirus	4.5e-19	34.8
AZN63725.1\|1354729_1355665_+	protein RarD	NA	NA	NA	NA
AZN63726.1\|1355987_1357445_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
AZN63727.1\|1357753_1358898_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN63728.1\|1359017_1359734_+	MFS transporter	NA	NA	NA	NA
AZN63729.1\|1359742_1360423_+	hypothetical protein	NA	NA	NA	NA
AZN63730.1\|1360475_1361327_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AZN63731.1\|1361439_1361820_+	transcriptional regulator	NA	NA	NA	NA
AZN63732.1\|1362222_1363437_+	GTPase ObgE	NA	NA	NA	NA
AZN63733.1\|1363463_1364597_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	7.6e-71	43.1
AZN63734.1\|1364656_1365253_-	undecaprenyl-diphosphatase	NA	NA	NA	NA
AZN63735.1\|1365381_1367589_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
AZN63736.1\|1367781_1368483_-	hypothetical protein	NA	NA	NA	NA
AZN63737.1\|1368955_1370329_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	1.0e-24	27.1
AZN63738.1\|1370331_1371864_+	aspartate aminotransferase family protein	NA	NA	NA	NA
AZN63739.1\|1372953_1373979_+	phosphonate ABC transporter substrate-binding protein	A0A1B1IWY0	uncultured_Mediterranean_phage	2.0e-62	40.4
AZN63740.1\|1374083_1375463_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
1374281:1374295	attL	NA	NA	NA	NA
AZN63741.1\|1375462_1376851_+	phosphate ABC transporter, permease protein PstA	NA	NA	NA	NA
AZN63742.1\|1376864_1377779_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-14	29.8
AZN63743.1\|1378068_1379031_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.9e-22	27.0
AZN63744.1\|1379110_1380322_-	aspartate aminotransferase family protein	NA	NA	NA	NA
AZN63745.1\|1380484_1380826_+	monothiol glutaredoxin, Grx4 family	NA	NA	NA	NA
AZN63746.1\|1380881_1383515_-\|protease	ATP-dependent protease	NA	NA	NA	NA
AZN63747.1\|1383696_1385838_+	MFS transporter	NA	NA	NA	NA
AZN63748.1\|1385962_1386364_+	lactoylglutathione lyase	NA	NA	NA	NA
AZN63749.1\|1386531_1387512_+	bile acid:sodium symporter	NA	NA	NA	NA
AZN63750.1\|1387717_1387945_+	50S ribosomal protein L31	NA	NA	NA	NA
AZN63751.1\|1388088_1390215_-	diguanylate phosphodiesterase	NA	NA	NA	NA
AZN63752.1\|1390196_1391942_-	GTPase	NA	NA	NA	NA
AZN63753.1\|1391959_1392976_-	EF-P beta-lysylation protein EpmB	NA	NA	NA	NA
AZN63754.1\|1393285_1393855_+	elongation factor P	NA	NA	NA	NA
AZN63755.1\|1394023_1396126_+	carbon starvation protein A	NA	NA	NA	NA
AZN63756.1\|1396136_1396439_+	DUF466 domain-containing protein	NA	NA	NA	NA
AZN63757.1\|1397111_1398023_+	AAA family ATPase	NA	NA	NA	NA
AZN63758.1\|1398039_1398939_+	DUF58 domain-containing protein	NA	NA	NA	NA
AZN63759.1\|1398948_1400940_+	transglutaminase	NA	NA	NA	NA
AZN63760.1\|1401235_1402246_+\|integrase	integrase	A0A0R6PHH4	Moraxella_phage	2.2e-82	48.5
AZN63761.1\|1402242_1402890_-	hypothetical protein	NA	NA	NA	NA
AZN63762.1\|1402984_1403266_-	hypothetical protein	NA	NA	NA	NA
AZN63763.1\|1403266_1403476_-	hypothetical protein	NA	NA	NA	NA
AZN63764.1\|1403468_1403762_-	hypothetical protein	NA	NA	NA	NA
AZN63765.1\|1403761_1404205_-	hypothetical protein	NA	NA	NA	NA
AZN63766.1\|1404204_1404795_-	HNH endonuclease	A0A2H4JIA5	uncultured_Caudovirales_phage	4.9e-21	32.6
1404446:1404460	attR	NA	NA	NA	NA
AZN63767.1\|1404972_1406191_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	2.2e-76	51.2
AZN63768.1\|1406489_1407240_+\|transposase	DDE transposase	A0A0N9SHJ4	Paenibacillus_phage	2.7e-24	44.9
AZN63769.1\|1407644_1409249_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	1.9e-144	54.5
AZN63770.1\|1409323_1409713_-\|transposase	transposase	NA	NA	NA	NA
AZN63771.1\|1409655_1410039_-\|transposase	transposase	NA	NA	NA	NA
AZN63772.1\|1411251_1412172_-	chromate resistance protein	NA	NA	NA	NA
AZN63773.1\|1412361_1413294_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	2.3e-57	40.5
AZN63774.1\|1413481_1413736_+	TIGR03643 family protein	NA	NA	NA	NA
AZN63775.1\|1413741_1413852_-	DUF2256 domain-containing protein	NA	NA	NA	NA
AZN63776.1\|1413887_1415411_-	cryptochrome/photolyase family protein	E3T4R9	Cafeteria_roenbergensis_virus	7.9e-47	27.1
AZN63777.1\|1415783_1416557_+	NADH pyrophosphatase	NA	NA	NA	NA
AZN63778.1\|1416726_1417275_+	hypothetical protein	A0A2P1EMA7	Moumouvirus	1.6e-18	39.0
AZN63779.1\|1417410_1418397_+	acyl-CoA desaturase	NA	NA	NA	NA
AZN63780.1\|1418393_1419677_+	dehydrogenase	NA	NA	NA	NA
AZN63781.1\|1419686_1420475_+	hypothetical protein	NA	NA	NA	NA
AZN63782.1\|1420471_1421677_+	SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	3.5e-42	31.9
AZN63783.1\|1421701_1422481_+	hypothetical protein	NA	NA	NA	NA
AZN63784.1\|1422489_1423539_+	SAM-dependent methyltransferase	NA	NA	NA	NA
AZN63785.1\|1423574_1424897_+	two-component sensor histidine kinase	NA	NA	NA	NA
AZN63786.1\|1424914_1425601_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	7.9e-31	38.2
AZN63787.1\|1426113_1427257_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN63788.1\|1427370_1427943_-	DUF2358 domain-containing protein	NA	NA	NA	NA
AZN63789.1\|1428056_1428950_-	hypothetical protein	NA	NA	NA	NA
AZN63790.1\|1429050_1430262_+	tryptophan synthase subunit beta	NA	NA	NA	NA
AZN63791.1\|1430258_1431044_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
AZN63792.1\|1431179_1431782_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.2e-43	49.0
AZN63793.1\|1431931_1433076_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN63794.1\|1433467_1433968_+	DNA starvation/stationary phase protection protein	W5S6G8	Pithovirus	2.1e-17	35.0
AZN63795.1\|1434281_1435214_-\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	1.9e-56	41.1
AZN63796.1\|1436515_1437031_-	chromate transporter	NA	NA	NA	NA
AZN63797.1\|1437027_1437603_-	chromate transporter	NA	NA	NA	NA
AZN63798.1\|1437711_1438596_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZN63799.1\|1440492_1441131_-	TetR family transcriptional regulator	NA	NA	NA	NA
AZN63800.1\|1441240_1442263_+	hypothetical protein	NA	NA	NA	NA
AZN63801.1\|1442274_1444092_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.0e-17	30.0
AZN63802.1\|1444102_1445233_+	hypothetical protein	NA	NA	NA	NA
AZN63803.1\|1445252_1446368_+	antibiotic ABC transporter permease	NA	NA	NA	NA
AZN63804.1\|1446542_1447187_+	RNA pseudouridine synthase	NA	NA	NA	NA
AZN63805.1\|1447323_1450161_+	RNA polymerase-binding ATPase	A0A1B1IUI1	uncultured_Mediterranean_phage	1.9e-22	36.6
AZN63806.1\|1450321_1450588_+	PAAR domain-containing protein	NA	NA	NA	NA
AZN63807.1\|1450725_1451541_+	alpha/beta hydrolase	NA	NA	NA	NA
AZN63808.1\|1451579_1452275_-	TetR family transcriptional regulator	NA	NA	NA	NA
AZN63809.1\|1452415_1453483_+	oxidoreductase	NA	NA	NA	NA
AZN63810.1\|1453497_1454592_+	acyl-CoA desaturase	NA	NA	NA	NA
AZN63811.1\|1454628_1454829_-	hypothetical protein	NA	NA	NA	NA
AZN63812.1\|1454989_1455646_-	phosphoserine phosphatase	NA	NA	NA	NA
AZN63813.1\|1455612_1456818_-	hypothetical protein	NA	NA	NA	NA
AZN63814.1\|1456831_1457035_+	hypothetical protein	NA	NA	NA	NA
AZN63815.1\|1458672_1458888_+	hypothetical protein	NA	NA	NA	NA
AZN63816.1\|1459166_1459376_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	7.5e-17	66.7
AZN63817.1\|1459509_1461114_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	1.9e-144	54.5
AZN63818.1\|1461188_1461578_-\|transposase	transposase	NA	NA	NA	NA
AZN63819.1\|1461520_1461904_-\|transposase	transposase	NA	NA	NA	NA
AZN63820.1\|1462237_1462525_+\|head,tail	phage head-tail adapter protein	A0A2H4JAM4	uncultured_Caudovirales_phage	6.0e-25	56.8

DBSCAN-SWA_7

1633090 : 1755705

108

Escherichia_phage(25.93%)

transposase,integrase

attL 1683633:1683649|attR 1738395:1738411

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN63975.1\|1633090_1634023_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	3.5e-58	40.9
AZN63976.1\|1634222_1635442_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	2.2e-76	51.2
AZN63977.1\|1635624_1635825_+	hypothetical protein	NA	NA	NA	NA
AZN63978.1\|1635892_1636153_+	hypothetical protein	NA	NA	NA	NA
AZN63979.1\|1636414_1636609_-	hypothetical protein	NA	NA	NA	NA
AZN63980.1\|1636721_1636973_+	hypothetical protein	NA	NA	NA	NA
AZN63981.1\|1637086_1638448_+	replication protein	Q4LAU7	Stenotrophomonas_phage	3.1e-18	30.5
AZN63982.1\|1638437_1638734_+	hypothetical protein	NA	NA	NA	NA
AZN65756.1\|1638746_1638923_+	hypothetical protein	NA	NA	NA	NA
AZN63983.1\|1638944_1639184_+	hypothetical protein	NA	NA	NA	NA
AZN63984.1\|1639294_1639612_+	hypothetical protein	NA	NA	NA	NA
AZN63985.1\|1639648_1640868_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.4e-78	53.2
AZN63986.1\|1641601_1641880_+	hypothetical protein	NA	NA	NA	NA
AZN63987.1\|1641943_1643272_+	hypothetical protein	NA	NA	NA	NA
AZN63988.1\|1643682_1644826_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN63989.1\|1644952_1645153_+	hypothetical protein	NA	NA	NA	NA
AZN63990.1\|1645765_1646800_-	efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
AZN63991.1\|1646820_1648353_-	MFS transporter	NA	NA	NA	NA
AZN63992.1\|1648349_1649822_-	multidrug transporter	NA	NA	NA	NA
AZN63993.1\|1650004_1650634_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AZN63994.1\|1650771_1651056_+	hypothetical protein	A0A2H4JBL5	uncultured_Caudovirales_phage	4.7e-22	69.0
AZN63995.1\|1651719_1652811_-	transcriptional regulator	NA	NA	NA	NA
AZN63996.1\|1653044_1654019_-	lipoyl synthase	NA	NA	NA	NA
AZN63997.1\|1654360_1655323_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AZN63998.1\|1655338_1656358_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
AZN63999.1\|1656359_1657895_+	diaminohydroxyphosphoribosylaminopyrimidine deaminase	NA	NA	NA	NA
AZN64000.1\|1657906_1659307_+	dihydrolipoyl dehydrogenase	NA	NA	NA	NA
AZN64001.1\|1659318_1660104_+	diacetyl reductase	NA	NA	NA	NA
AZN64002.1\|1660125_1661184_+	butanediol dehydrogenase	NA	NA	NA	NA
AZN64003.1\|1661514_1661751_-	DUF2132 domain-containing protein	NA	NA	NA	NA
AZN64004.1\|1662486_1663551_-	hypothetical protein	NA	NA	NA	NA
AZN64005.1\|1663886_1665068_+	MFS transporter	NA	NA	NA	NA
AZN64006.1\|1665404_1666298_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZN64007.1\|1666683_1667583_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZN64008.1\|1667738_1668590_+	2,5-diketo-D-gluconic acid reductase	A0A2H4PQR8	Staphylococcus_phage	4.2e-50	40.8
AZN64009.1\|1668611_1669661_+	alpha/beta hydrolase	NA	NA	NA	NA
AZN64010.1\|1669704_1670817_+	alpha/beta hydrolase	NA	NA	NA	NA
AZN64011.1\|1670820_1671960_+	carboxymuconolactone decarboxylase	NA	NA	NA	NA
AZN64012.1\|1672035_1673085_+	hydroxyacid dehydrogenase	A0A2K9L7I1	Tupanvirus	7.7e-78	43.9
AZN64013.1\|1673220_1675071_+	hypothetical protein	NA	NA	NA	NA
AZN64014.1\|1675156_1676248_+	alpha/beta hydrolase	NA	NA	NA	NA
AZN64015.1\|1676263_1676959_+	flavodoxin	NA	NA	NA	NA
AZN64016.1\|1677060_1678212_+	Bcr/CflA family drug resistance efflux transporter	S4TR35	Salmonella_phage	5.8e-18	24.4
AZN64017.1\|1678510_1679443_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	4.6e-58	40.9
AZN64018.1\|1679690_1680119_+	DedA family protein	NA	NA	NA	NA
AZN64019.1\|1680393_1680660_-	transcriptional repressor RcnR to maintain nickel and cobalt homeostasis	NA	NA	NA	NA
AZN64020.1\|1680717_1681686_+	cation transporter	NA	NA	NA	NA
AZN64021.1\|1682140_1684021_+	potassium transporter Kup	A7K9V6	Acanthocystis_turfacea_chlorella_virus	1.0e-75	35.0
1683633:1683649	attL	NA	NA	NA	NA
AZN64022.1\|1684063_1685422_-	chromate transporter	A0A219VHC2	Ochrobactrum_phage	1.4e-31	69.1
AZN64023.1\|1685424_1686345_-	chromate resistance protein	NA	NA	NA	NA
AZN64024.1\|1686534_1687467_+\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	2.3e-57	40.5
AZN64025.1\|1688524_1689475_-\|transposase	IS481 family transposase	E2FK51	Porcine_endogenous_retrovirus	2.7e-05	30.1
AZN64026.1\|1689675_1689996_-	transcriptional regulator	NA	NA	NA	NA
AZN64027.1\|1690248_1690755_+	hypothetical protein	NA	NA	NA	NA
AZN64028.1\|1690830_1691975_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN64029.1\|1692229_1692667_-	hypothetical protein	NA	NA	NA	NA
AZN64030.1\|1692668_1695002_-	hypothetical protein	NA	NA	NA	NA
AZN64031.1\|1694991_1696572_-\|integrase	integrase	NA	NA	NA	NA
AZN64032.1\|1696583_1697930_-\|integrase	integrase	NA	NA	NA	NA
AZN64033.1\|1698180_1699515_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
AZN64034.1\|1700473_1701331_-	cation transporter	NA	NA	NA	NA
AZN64035.1\|1701413_1702214_-	hypothetical protein	NA	NA	NA	NA
AZN64036.1\|1702258_1702753_-	flavin reductase	NA	NA	NA	NA
AZN64037.1\|1702856_1703885_-	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase	NA	NA	NA	NA
AZN64038.1\|1703927_1704932_-	hypothetical protein	NA	NA	NA	NA
AZN64039.1\|1705420_1705699_+	hypothetical protein	NA	NA	NA	NA
AZN64040.1\|1705963_1706236_-	hypothetical protein	NA	NA	NA	NA
AZN64041.1\|1707706_1707895_-	hypothetical protein	NA	NA	NA	NA
AZN64042.1\|1708027_1708411_-\|transposase	transposase	NA	NA	NA	NA
AZN64043.1\|1708686_1709385_+	DUF1826 domain-containing protein	NA	NA	NA	NA
AZN64044.1\|1709845_1710895_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
AZN64045.1\|1711117_1712193_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.3e-45	40.4
AZN64046.1\|1712411_1712726_+	four-helix bundle copper-binding protein	NA	NA	NA	NA
AZN64047.1\|1712812_1713106_-	addiction module antidote protein, HigA family	A0A0M3LPV0	Mannheimia_phage	2.8e-09	39.8
AZN64048.1\|1713119_1713398_-	Killer protein	A0A2L1IV28	Escherichia_phage	8.7e-21	44.6
AZN64049.1\|1713923_1714109_-	hypothetical protein	NA	NA	NA	NA
AZN64050.1\|1717826_1718063_-	hypothetical protein	NA	NA	NA	NA
AZN64051.1\|1718302_1718458_+	hypothetical protein	NA	NA	NA	NA
AZN64052.1\|1718639_1719686_-	cation transporter	NA	NA	NA	NA
AZN64053.1\|1719747_1720818_-\|transposase	transposase	Q9G0F2	Phage_Gifsy-1	2.4e-26	30.9
AZN64054.1\|1720965_1721250_-	hypothetical protein	NA	NA	NA	NA
AZN64055.1\|1721398_1722208_-	short chain dehydrogenase	NA	NA	NA	NA
AZN64056.1\|1722258_1723110_-	hypothetical protein	NA	NA	NA	NA
AZN64057.1\|1723194_1724742_-	hypothetical protein	A0A1V0SBX8	Catovirus	3.3e-16	25.0
AZN64058.1\|1724790_1725534_-	hypothetical protein	NA	NA	NA	NA
AZN64059.1\|1725762_1726746_-	Ion transport protein	NA	NA	NA	NA
AZN64060.1\|1727014_1728142_-	hypothetical protein	NA	NA	NA	NA
AZN64061.1\|1728143_1730897_-	multidrug ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.1e-26	30.4
AZN64062.1\|1730893_1731955_-	hemolysin D	NA	NA	NA	NA
AZN64063.1\|1732049_1733492_-	RND transporter	NA	NA	NA	NA
AZN64064.1\|1733665_1733899_-	hypothetical protein	NA	NA	NA	NA
AZN64065.1\|1734158_1736915_-	aconitate hydratase 1	NA	NA	NA	NA
AZN64066.1\|1737479_1737944_-	MarR family transcriptional regulator	NA	NA	NA	NA
AZN64067.1\|1738631_1739204_+	DUF2358 domain-containing protein	NA	NA	NA	NA
1738395:1738411	attR	NA	NA	NA	NA
AZN64068.1\|1739173_1739674_+	hypothetical protein	NA	NA	NA	NA
AZN64069.1\|1739692_1740379_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	3.1e-27	36.4
AZN64070.1\|1740393_1741722_-	two-component sensor histidine kinase	NA	NA	NA	NA
AZN64071.1\|1741752_1742802_-	SAM-dependent methyltransferase	NA	NA	NA	NA
AZN64072.1\|1742810_1743590_-	hypothetical protein	NA	NA	NA	NA
AZN64073.1\|1743624_1744824_-	SAM-dependent methyltransferase	NA	NA	NA	NA
AZN64074.1\|1744827_1745613_-	hypothetical protein	NA	NA	NA	NA
AZN64075.1\|1746824_1747968_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	8.3e-17	28.7
AZN64076.1\|1748628_1749102_-	low molecular weight phosphatase family protein	A0A2H4J8A6	uncultured_Caudovirales_phage	1.3e-37	52.6
AZN64077.1\|1749105_1749426_-	transcriptional regulator	A0A2H4J145	uncultured_Caudovirales_phage	4.4e-24	63.5
AZN64078.1\|1749484_1749913_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	3.1e-41	57.6
AZN64079.1\|1750208_1753955_-	hypothetical protein	NA	NA	NA	NA
AZN64080.1\|1753951_1754326_-	hypothetical protein	NA	NA	NA	NA
AZN64081.1\|1754485_1755705_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	5.8e-77	51.9

DBSCAN-SWA_8

1776369 : 1839438

Paenibacillus_phage(30.0%)

transposase,integrase

attL 1835217:1835232|attR 1840737:1840752

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN64103.1\|1776369_1777589_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	2.2e-76	51.2
AZN64104.1\|1777663_1778425_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
AZN64105.1\|1778555_1779710_+	MFS transporter	NA	NA	NA	NA
AZN64106.1\|1779765_1781256_-	amidase	NA	NA	NA	NA
AZN64107.1\|1781310_1782741_-	response regulator	G3MA91	Bacillus_virus	2.9e-19	35.5
AZN64108.1\|1782997_1783225_-	hypothetical protein	NA	NA	NA	NA
AZN64109.1\|1783407_1784652_-	D-amino acid dehydrogenase	NA	NA	NA	NA
AZN64110.1\|1785099_1785819_-	hypothetical protein	NA	NA	NA	NA
AZN64111.1\|1786289_1787381_-	chorismate synthase	A0A291AU41	Pandoravirus	8.9e-77	43.9
AZN64112.1\|1787396_1788407_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
AZN64113.1\|1788512_1788935_-	hypothetical protein	NA	NA	NA	NA
AZN64114.1\|1789128_1789434_+	hypothetical protein	NA	NA	NA	NA
AZN64115.1\|1789591_1790965_+	ABC transporter	M1HE59	Acanthocystis_turfacea_Chlorella_virus	3.6e-06	25.5
AZN64116.1\|1791187_1792483_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
AZN64117.1\|1792500_1793700_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
AZN64118.1\|1794399_1794963_+	transglycosylase	A0A0F7INF9	Delftia_phage	1.7e-07	35.5
AZN64119.1\|1801027_1801690_-	hypothetical protein	NA	NA	NA	NA
AZN64120.1\|1801888_1802482_-	nitroreductase family protein	NA	NA	NA	NA
AZN64121.1\|1803438_1804189_+\|transposase	DDE transposase	A0A0N9SHJ4	Paenibacillus_phage	2.7e-24	44.9
AZN64122.1\|1804319_1805066_+\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.6e-13	35.0
AZN64123.1\|1805263_1805836_+	acyltransferase	NA	NA	NA	NA
AZN64124.1\|1806097_1806847_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
AZN64125.1\|1806848_1807070_-	hypothetical protein	NA	NA	NA	NA
AZN64126.1\|1807227_1807698_-	transcriptional regulator	NA	NA	NA	NA
AZN64127.1\|1807975_1808740_-	glutathione S-transferase	NA	NA	NA	NA
AZN64128.1\|1809120_1810323_+	SfnB family sulfur acquisition oxidoreductase	NA	NA	NA	NA
AZN64129.1\|1810333_1811557_+	SfnB family sulfur acquisition oxidoreductase	NA	NA	NA	NA
AZN64130.1\|1811556_1812975_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
AZN64131.1\|1812997_1813840_+	methionine transporter	NA	NA	NA	NA
AZN64132.1\|1813849_1814686_+	methionine transporter	NA	NA	NA	NA
AZN64133.1\|1814697_1815762_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-32	34.7
AZN64134.1\|1815742_1816402_+	ABC transporter permease	NA	NA	NA	NA
AZN64135.1\|1816630_1817341_+	haloacid dehalogenase, type II	NA	NA	NA	NA
AZN64136.1\|1817486_1818578_+	redox-regulated ATPase YchF	NA	NA	NA	NA
AZN64137.1\|1818768_1819107_+	hypothetical protein	NA	NA	NA	NA
AZN64138.1\|1819166_1819706_-	hypothetical protein	NA	NA	NA	NA
AZN64139.1\|1819823_1820519_+	cyclic nucleotide-binding protein	NA	NA	NA	NA
AZN64140.1\|1820821_1821304_-	hypothetical protein	NA	NA	NA	NA
AZN64141.1\|1821405_1822158_+	hypothetical protein	NA	NA	NA	NA
AZN64142.1\|1822154_1822502_+	L-valine transporter subunit YgaH	NA	NA	NA	NA
AZN64143.1\|1822745_1823951_+	phosphoribosylglycinamide formyltransferase 2	NA	NA	NA	NA
AZN64144.1\|1823979_1826646_+	[protein-PII] uridylyltransferase	NA	NA	NA	NA
AZN64145.1\|1826670_1827840_+	succinyldiaminopimelate transaminase	NA	NA	NA	NA
AZN64146.1\|1827896_1829831_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
AZN64147.1\|1829899_1830650_+\|transposase	DDE transposase	A0A0N9SHJ4	Paenibacillus_phage	2.7e-24	44.9
AZN64148.1\|1830654_1830936_-	hypothetical protein	NA	NA	NA	NA
AZN64149.1\|1831105_1831729_-	lysine transporter LysE	NA	NA	NA	NA
AZN64150.1\|1832650_1833133_-	glutathione peroxidase	Q70H87	Fowlpox_virus	1.7e-24	39.0
AZN64151.1\|1833129_1833549_-	peptide-methionine (R)-S-oxide reductase	NA	NA	NA	NA
AZN64152.1\|1833776_1835207_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
1835217:1835232	attL	NA	NA	NA	NA
AZN64153.1\|1835375_1836854_+\|integrase	integrase	NA	NA	NA	NA
AZN64154.1\|1836843_1839438_+\|integrase	integrase	NA	NA	NA	NA
1840737:1840752	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1991828 : 2114882

111

Escherichia_phage(13.04%)

holin,transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN64302.1\|1991828_1992972_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN64303.1\|1993050_1993275_+	hypothetical protein	NA	NA	NA	NA
AZN64304.1\|1993340_1993937_-	disulfide bond formation protein DsbA	NA	NA	NA	NA
AZN64305.1\|1993948_1994716_-	glucose 1-dehydrogenase	NA	NA	NA	NA
AZN64306.1\|1994810_1995374_+	TetR family transcriptional regulator	NA	NA	NA	NA
AZN64307.1\|1995490_1996192_+	glutamine amidotransferase	NA	NA	NA	NA
AZN64308.1\|1996428_1997572_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN64309.1\|1997632_1998400_-	hypothetical protein	Q8W6R2	Burkholderia_virus	2.8e-16	32.5
AZN64310.1\|1998909_1999506_-	polyisoprenoid-binding protein	NA	NA	NA	NA
AZN64311.1\|2000193_2000409_-	hypothetical protein	NA	NA	NA	NA
AZN64312.1\|2000525_2002514_-	transketolase	NA	NA	NA	NA
AZN64313.1\|2003234_2004401_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.4e-122	60.4
AZN64314.1\|2005966_2006257_-	hypothetical protein	NA	NA	NA	NA
AZN64315.1\|2006526_2006739_+	hypothetical protein	NA	NA	NA	NA
AZN64316.1\|2006700_2007342_-	threonine transporter RhtB	NA	NA	NA	NA
AZN64317.1\|2007474_2008056_-	FxsA protein	NA	NA	NA	NA
AZN64318.1\|2008178_2008724_+	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
AZN64319.1\|2008727_2009054_-	hypothetical protein	NA	NA	NA	NA
AZN64320.1\|2009181_2009988_-	hypothetical protein	NA	NA	NA	NA
AZN64321.1\|2010073_2010886_-	hypothetical protein	NA	NA	NA	NA
AZN64322.1\|2011029_2012328_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
AZN64323.1\|2012370_2012991_-	thiamine phosphate synthase	NA	NA	NA	NA
AZN64324.1\|2013390_2014137_+\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.6e-13	35.0
AZN64325.1\|2014369_2014753_-	hypothetical protein	NA	NA	NA	NA
AZN64326.1\|2015038_2016499_+	CYTH domain-containing protein	NA	NA	NA	NA
AZN64327.1\|2016898_2018359_+	hypothetical protein	NA	NA	NA	NA
AZN64328.1\|2018425_2019058_-	hypothetical protein	NA	NA	NA	NA
AZN64329.1\|2019171_2019567_+	hypothetical protein	NA	NA	NA	NA
AZN64330.1\|2019688_2020753_+	amidohydrolase	NA	NA	NA	NA
AZN64331.1\|2020845_2023623_-	peptidase M16	A0A2P1EIE5	Megavirus	1.8e-20	31.8
AZN64332.1\|2023769_2024597_-	phenazine biosynthesis protein PhzF	NA	NA	NA	NA
AZN64333.1\|2024748_2026137_-	L-cystine transporter	NA	NA	NA	NA
AZN64334.1\|2026296_2026902_+	flavin reductase	NA	NA	NA	NA
AZN64335.1\|2027010_2028213_+	MFS transporter	NA	NA	NA	NA
AZN64336.1\|2028417_2028969_-	peptidase M23	A0A7K9	Microcystis_virus	1.2e-10	41.8
AZN64337.1\|2029750_2030683_-\|transposase	IS5/IS1182 family transposase	Q1MVF0	Enterobacteria_phage	7.9e-58	40.5
AZN64338.1\|2030841_2032095_-	isocitrate dehydrogenase (NADP(+))	Q77Z09	Phage_21	1.3e-15	75.9
AZN64339.1\|2032292_2033081_+	pseudouridine synthase	NA	NA	NA	NA
AZN64340.1\|2034050_2036282_-	isocitrate dehydrogenase, NADP-dependent	NA	NA	NA	NA
AZN64341.1\|2036794_2037193_+	hydroxyisourate hydrolase	NA	NA	NA	NA
AZN64342.1\|2037277_2038981_-\|protease	serine protease	NA	NA	NA	NA
AZN64343.1\|2039160_2040471_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	5.4e-36	33.2
AZN64344.1\|2040595_2041897_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
AZN64345.1\|2042036_2042519_+	peptidylprolyl isomerase	NA	NA	NA	NA
AZN64346.1\|2042859_2044329_-	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
AZN64347.1\|2044351_2045446_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
AZN64348.1\|2045747_2046737_+	biotin synthase BioB	NA	NA	NA	NA
AZN64349.1\|2046804_2047041_-	hypothetical protein	NA	NA	NA	NA
AZN64350.1\|2047167_2047365_-	hypothetical protein	NA	NA	NA	NA
AZN64351.1\|2047644_2049282_+	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	7.4e-27	27.5
AZN64352.1\|2049350_2050277_-	IroE protein	NA	NA	NA	NA
AZN64353.1\|2050354_2050543_-	hypothetical protein	NA	NA	NA	NA
AZN64354.1\|2050527_2050989_-	hypothetical protein	NA	NA	NA	NA
AZN64355.1\|2051175_2052312_-	2-methylcitrate synthase	NA	NA	NA	NA
AZN64356.1\|2052316_2053201_-	methylisocitrate lyase	NA	NA	NA	NA
AZN64357.1\|2053447_2054098_+	TetR family transcriptional regulator	NA	NA	NA	NA
AZN64358.1\|2054219_2055140_+	ornithine carbamoyltransferase	NA	NA	NA	NA
AZN64359.1\|2055230_2055704_+	hypothetical protein	NA	NA	NA	NA
AZN64360.1\|2055731_2056085_-	hypothetical protein	A0A218MNG8	uncultured_virus	1.4e-26	54.6
AZN64361.1\|2056172_2058449_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	3.7e-165	43.7
AZN64362.1\|2058458_2058875_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	3.4e-13	45.2
AZN64363.1\|2058892_2059639_-	hypothetical protein	NA	NA	NA	NA
AZN64364.1\|2059718_2060768_-	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
AZN64365.1\|2062186_2062933_-\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.6e-13	35.0
AZN64366.1\|2063035_2063719_-	hypothetical protein	NA	NA	NA	NA
AZN64367.1\|2063847_2064519_-	ribose-5-phosphate isomerase	NA	NA	NA	NA
AZN64368.1\|2064626_2066165_+	threonine ammonia-lyase	NA	NA	NA	NA
AZN64369.1\|2066205_2066700_-	hypothetical protein	NA	NA	NA	NA
AZN64370.1\|2066850_2067504_+	potassium transporter TrkA	NA	NA	NA	NA
AZN64371.1\|2067500_2068850_+	potassium transporter TrkH	NA	NA	NA	NA
AZN64372.1\|2068910_2070050_-	phospholipase	NA	NA	NA	NA
AZN64373.1\|2070067_2073007_-	peptidase M16	NA	NA	NA	NA
AZN64374.1\|2073754_2074759_+	adenosine kinase	NA	NA	NA	NA
AZN64375.1\|2074758_2075085_+	Rieske	NA	NA	NA	NA
AZN64376.1\|2075103_2075721_+	hypothetical protein	NA	NA	NA	NA
AZN64377.1\|2076404_2076596_+	hypothetical protein	NA	NA	NA	NA
AZN64378.1\|2076595_2078176_+	cytochrome d terminal oxidase subunit 1	NA	NA	NA	NA
AZN64379.1\|2078172_2079318_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
AZN64380.1\|2079342_2079444_+	cytochrome bd-I oxidase subunit CydX	NA	NA	NA	NA
AZN64381.1\|2079447_2079750_+	cytochrome bd biosynthesis protein	NA	NA	NA	NA
AZN64382.1\|2079804_2080419_-	hypothetical protein	NA	NA	NA	NA
AZN64383.1\|2080431_2082492_-\|holin	high-affinity choline transporter BetT	A0A2I7QNT1	Vibrio_phage	1.0e-20	27.2
AZN64384.1\|2083039_2083666_+	transcriptional regulator BetI	NA	NA	NA	NA
AZN64385.1\|2083658_2085131_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
AZN64386.1\|2085251_2086916_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	8.8e-60	32.1
AZN64387.1\|2087414_2089049_+	malate:quinone oxidoreductase	NA	NA	NA	NA
AZN64388.1\|2089121_2090396_+	MFS transporter	NA	NA	NA	NA
AZN64389.1\|2090452_2090938_+	hypothetical protein	NA	NA	NA	NA
AZN64390.1\|2091019_2092156_-	rod shape-determining protein RodA	NA	NA	NA	NA
AZN64391.1\|2092269_2092989_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
AZN64392.1\|2092948_2093350_-	cell division protein FtsB	NA	NA	NA	NA
AZN64393.1\|2093357_2094647_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	9.0e-137	60.0
AZN64394.1\|2094707_2095565_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	5.6e-50	41.2
AZN64395.1\|2095596_2097237_-	CTP synthetase	A0A1J0FA14	Only_Syngen_Nebraska_virus	5.3e-150	52.8
AZN64396.1\|2097463_2097865_+	internalin	NA	NA	NA	NA
AZN64397.1\|2097924_2098815_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZN64398.1\|2098925_2099732_+	2,5-didehydrogluconate reductase B	A0A2H4PQR8	Staphylococcus_phage	1.7e-37	35.0
AZN64399.1\|2099740_2100910_+	MFS transporter	NA	NA	NA	NA
AZN64400.1\|2100969_2102067_-	alpha/beta hydrolase	NA	NA	NA	NA
AZN64401.1\|2102147_2102561_-	hypothetical protein	NA	NA	NA	NA
AZN64402.1\|2102752_2104777_-	NADPH-dependent 2,4-dienoyl-CoA reductase	NA	NA	NA	NA
AZN64403.1\|2104946_2105486_+	PadR family transcriptional regulator	NA	NA	NA	NA
AZN64404.1\|2105508_2106420_+	alpha/beta hydrolase	NA	NA	NA	NA
AZN64405.1\|2106577_2107357_-	glutathione S-transferase	NA	NA	NA	NA
AZN64406.1\|2107406_2107919_-	ribonuclease activity regulator protein RraA	NA	NA	NA	NA
AZN64407.1\|2107927_2108593_-	nucleoside-diphosphate sugar epimerase	NA	NA	NA	NA
AZN64408.1\|2108806_2109073_+	30S ribosomal protein S20	NA	NA	NA	NA
AZN64409.1\|2111555_2112699_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN64410.1\|2112717_2113272_-	hypothetical protein	NA	NA	NA	NA
AZN64411.1\|2113640_2114081_+	hypothetical protein	NA	NA	NA	NA
AZN64412.1\|2114135_2114882_-\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.6e-13	35.0

DBSCAN-SWA_10

2246154 : 2256929

Indivirus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN64528.1\|2246154_2248788_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	4.2e-32	24.5
AZN64529.1\|2248995_2249319_+	ferredoxin	NA	NA	NA	NA
AZN64530.1\|2249451_2250171_+	peptidase M15	NA	NA	NA	NA
AZN64531.1\|2250304_2250970_+	methyltransferase	S5YRC3	Mycobacterium_phage	2.3e-27	36.8
AZN64532.1\|2251111_2251954_-	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	3.8e-35	33.9
AZN64533.1\|2252082_2252694_-	acyltransferase	M1HKK6	Paramecium_bursaria_Chlorella_virus	2.0e-09	50.8
AZN64534.1\|2252686_2253283_-	hypothetical protein	A0A1X9I5T8	Streptococcus_phage	2.4e-23	39.5
AZN64535.1\|2253529_2254276_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-20	26.2
AZN64536.1\|2254275_2254842_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
AZN64537.1\|2254831_2255374_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
AZN64538.1\|2255408_2255948_-	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	NA	NA	NA	NA
AZN64539.1\|2255951_2256929_-	D-arabinose 5-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	1.6e-37	31.1

DBSCAN-SWA_11

2938780 : 3026818

uncultured_Caudovirales_phage(32.35%)

transposase,terminase,head,tail,tRNA,portal,capsid,integrase,protease

attL 2971004:2971021|attR 3011339:3011356

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN65146.1\|2938780_2940082_-\|transposase	DDE transposase	NA	NA	NA	NA
AZN65147.1\|2940174_2941155_-	AraC family transcriptional regulator	NA	NA	NA	NA
AZN65148.1\|2941493_2941991_-	hypothetical protein	NA	NA	NA	NA
AZN65149.1\|2942028_2942505_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZN65150.1\|2942694_2943732_+	AraC family transcriptional regulator	NA	NA	NA	NA
AZN65151.1\|2943780_2944725_-	phenol degradation protein meta	NA	NA	NA	NA
AZN65152.1\|2944794_2945939_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN65153.1\|2946064_2946589_-	flavin reductase	NA	NA	NA	NA
AZN65154.1\|2946608_2947847_-	alanine-phosphoribitol ligase	NA	NA	NA	NA
AZN65155.1\|2947868_2948654_-	short-chain dehydrogenase	NA	NA	NA	NA
AZN65156.1\|2950503_2952165_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	5.5e-171	55.1
AZN65157.1\|2954258_2954648_-\|transposase	transposase	NA	NA	NA	NA
AZN65158.1\|2954590_2954974_-\|transposase	transposase	NA	NA	NA	NA
AZN65159.1\|2955433_2958538_-	DEAD/DEAH box helicase	A0A220A398	Liberibacter_phage	1.9e-71	30.1
AZN65160.1\|2958749_2959229_-	hypothetical protein	Q71TB7	Escherichia_phage	5.9e-25	38.3
AZN65161.1\|2959225_2959924_-	hypothetical protein	Q71TB8	Escherichia_phage	1.8e-62	51.1
AZN65162.1\|2959926_2961213_-	restriction endonuclease subunit S	NA	NA	NA	NA
AZN65163.1\|2961368_2962802_-	ATP-dependent DNA helicase	NA	NA	NA	NA
AZN65164.1\|2962791_2964522_-	restriction endonuclease subunit M	NA	NA	NA	NA
AZN65165.1\|2964764_2965667_-	hydrolase or metal-binding protein	NA	NA	NA	NA
AZN65166.1\|2965811_2966855_-	YqaJ-like viral recombinase	A0A139ZPJ9	Marinitoga_camini_virus	7.5e-41	42.1
AZN65167.1\|2966998_2968045_-	hypothetical protein	A0A0H4INH5	Stenotrophomonas_phage	2.9e-56	37.4
AZN65168.1\|2968136_2968439_-	hypothetical protein	NA	NA	NA	NA
AZN65169.1\|2968560_2968941_-	hypothetical protein	NA	NA	NA	NA
AZN65170.1\|2968952_2969534_-	hypothetical protein	NA	NA	NA	NA
AZN65171.1\|2969552_2969813_-	hypothetical protein	NA	NA	NA	NA
AZN65172.1\|2970800_2971952_+	hypothetical protein	NA	NA	NA	NA
2971004:2971021	attL	NA	NA	NA	NA
AZN65173.1\|2972121_2972370_+	hypothetical protein	NA	NA	NA	NA
AZN65174.1\|2972359_2972557_+	hypothetical protein	NA	NA	NA	NA
AZN65175.1\|2972618_2973545_+	hypothetical protein	NA	NA	NA	NA
AZN65176.1\|2974029_2975249_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-77	51.9
AZN65177.1\|2975826_2976099_+	pyocin activator protein PrtN	NA	NA	NA	NA
AZN65178.1\|2976082_2977231_-\|integrase	integrase	A0A2H4J8L8	uncultured_Caudovirales_phage	3.1e-96	48.0
AZN65179.1\|2977570_2977834_-	hypothetical protein	NA	NA	NA	NA
AZN65180.1\|2977833_2978130_-	anaerobic dehydrogenase	A0A1B2IBL3	Erwinia_phage	3.1e-16	39.6
AZN65181.1\|2978130_2978637_-	lysozyme	A0A0B5L5F7	Acinetobacter_phage	1.3e-59	66.7
AZN65182.1\|2978626_2978908_-	hypothetical protein	NA	NA	NA	NA
AZN65183.1\|2978969_2979824_-	hypothetical protein	NA	NA	NA	NA
AZN65184.1\|2979880_2982670_-	hypothetical protein	A0A1X9IAH9	Xanthomonas_phage	2.3e-97	31.8
AZN65185.1\|2982635_2982857_-	hypothetical protein	A0A076FR11	Pseudomonas_phage	5.3e-05	46.9
AZN65186.1\|2982853_2983072_-	hypothetical protein	NA	NA	NA	NA
AZN65187.1\|2983073_2984132_-	hypothetical protein	NA	NA	NA	NA
AZN65188.1\|2984128_2985274_-	hypothetical protein	A0A2H4J3F5	uncultured_Caudovirales_phage	1.5e-58	35.6
AZN65189.1\|2985270_2987787_-	hypothetical protein	A0A2H4J326	uncultured_Caudovirales_phage	2.7e-100	33.8
AZN65190.1\|2987848_2988334_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
AZN65191.1\|2988427_2989081_-	hypothetical protein	B0FED5	Escherichia_phage	1.9e-34	58.3
AZN65192.1\|2989458_2989668_-	hypothetical protein	NA	NA	NA	NA
AZN65193.1\|2990119_2990605_-	hypothetical protein	A0A2H4J511	uncultured_Caudovirales_phage	7.3e-23	37.5
AZN65194.1\|2990680_2991037_-	hypothetical protein	NA	NA	NA	NA
AZN65195.1\|2991033_2991522_-	hypothetical protein	A0A2H4JB20	uncultured_Caudovirales_phage	4.9e-27	41.6
AZN65196.1\|2991532_2991871_-\|head,tail	phage head-tail adapter protein	A0A1J0GUY4	Halomonas_phage	4.6e-16	42.5
AZN65759.1\|2991874_2992126_-	hypothetical protein	NA	NA	NA	NA
AZN65197.1\|2992159_2992414_-	hypothetical protein	NA	NA	NA	NA
AZN65198.1\|2992423_2992711_-	hypothetical protein	NA	NA	NA	NA
AZN65199.1\|2992691_2993966_-\|portal	phage portal protein	A0A2H4JB65	uncultured_Caudovirales_phage	8.1e-122	52.9
AZN65200.1\|2993978_2994320_-	hypothetical protein	NA	NA	NA	NA
AZN65201.1\|2994372_2995704_-\|capsid	phage major capsid protein	A0A0R6PCM7	Moraxella_phage	5.3e-124	54.0
AZN65202.1\|2995700_2996330_-	peptidase U35	A0A0R6PCV7	Moraxella_phage	2.2e-40	46.7
AZN65203.1\|2996337_2996526_-	hypothetical protein	NA	NA	NA	NA
AZN65204.1\|2996522_2998211_-\|terminase	terminase	A0A2H4J6B3	uncultured_Caudovirales_phage	1.3e-191	57.7
AZN65205.1\|2998212_2998689_-	hypothetical protein	A0A2H4J8R0	uncultured_Caudovirales_phage	7.4e-20	41.1
AZN65206.1\|2999509_2999818_-	HNH endonuclease	A0A0R6PHK1	Moraxella_phage	7.4e-21	53.2
AZN65207.1\|2999817_3000192_-	hypothetical protein	NA	NA	NA	NA
AZN65208.1\|3000376_3000850_-	hypothetical protein	NA	NA	NA	NA
AZN65209.1\|3001220_3003032_-	hypothetical protein	A0A2H4JF22	uncultured_Caudovirales_phage	8.2e-51	28.7
AZN65210.1\|3003028_3003937_-	hypothetical protein	A0A0R6PHP8	Moraxella_phage	1.0e-49	35.2
AZN65211.1\|3003936_3004437_-	Rha family transcriptional regulator	NA	NA	NA	NA
AZN65212.1\|3004466_3004667_-	ribonuclease D	NA	NA	NA	NA
AZN65213.1\|3004763_3005417_+	DNA-binding protein	A0A0P0IYD9	Acinetobacter_phage	6.0e-28	35.8
AZN65214.1\|3005569_3005890_+	hypothetical protein	NA	NA	NA	NA
AZN65215.1\|3005886_3006333_+	hypothetical protein	NA	NA	NA	NA
AZN65216.1\|3006465_3006657_+	hypothetical protein	NA	NA	NA	NA
AZN65217.1\|3006692_3006950_+	hypothetical protein	A0A2H4JC88	uncultured_Caudovirales_phage	8.9e-12	37.8
AZN65218.1\|3006939_3007383_+	hypothetical protein	NA	NA	NA	NA
AZN65219.1\|3007379_3007808_+	hypothetical protein	NA	NA	NA	NA
AZN65220.1\|3007865_3008198_+	hypothetical protein	NA	NA	NA	NA
AZN65221.1\|3008194_3008563_+	hypothetical protein	NA	NA	NA	NA
AZN65222.1\|3008562_3008892_+	hypothetical protein	NA	NA	NA	NA
AZN65223.1\|3008888_3010082_-\|integrase	integrase	A0A2H4J8L8	uncultured_Caudovirales_phage	3.1e-75	40.2
AZN65224.1\|3010201_3011227_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
AZN65225.1\|3011289_3011799_-	hypothetical protein	NA	NA	NA	NA
3011339:3011356	attR	NA	NA	NA	NA
AZN65226.1\|3013067_3013835_-\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	S4VW33	Pandoravirus	9.5e-17	30.2
AZN65227.1\|3013964_3016718_-	aconitate hydratase 1	NA	NA	NA	NA
AZN65228.1\|3016841_3017663_-	hydrolase	NA	NA	NA	NA
AZN65229.1\|3017669_3018620_-	hypothetical protein	NA	NA	NA	NA
AZN65230.1\|3018667_3019486_-	hypothetical protein	NA	NA	NA	NA
AZN65231.1\|3019576_3021166_-	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	4.7e-10	31.2
AZN65232.1\|3021547_3022054_-	hypothetical protein	NA	NA	NA	NA
AZN65233.1\|3022278_3024357_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	4.4e-16	32.3
AZN65234.1\|3024622_3026818_-\|tail,protease	tail-specific protease	A0A0R6PIZ1	Moraxella_phage	6.0e-173	46.2

DBSCAN-SWA_12

3399560 : 3448139

uncultured_Caudovirales_phage(30.77%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN65573.1\|3399560_3400649_+\|transposase	IS3 family transposase	NA	NA	NA	NA
AZN65574.1\|3400746_3400953_-	hypothetical protein	NA	NA	NA	NA
AZN65575.1\|3401072_3401885_-	hypothetical protein	NA	NA	NA	NA
AZN65576.1\|3401889_3404325_-	peptidase M23	A0A2H4JIA8	uncultured_Caudovirales_phage	3.4e-76	30.3
AZN65577.1\|3404326_3407632_-	type VI secretion system protein	A0A2H4JCD4	uncultured_Caudovirales_phage	0.0e+00	62.9
AZN65578.1\|3407783_3409484_-	NAD-dependent malic enzyme	NA	NA	NA	NA
AZN65579.1\|3409756_3410356_+	hypothetical protein	NA	NA	NA	NA
AZN65580.1\|3410364_3410649_-	hypothetical protein	NA	NA	NA	NA
AZN65581.1\|3410826_3412632_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
AZN65582.1\|3412910_3413513_+	SPOR domain-containing protein	NA	NA	NA	NA
AZN65583.1\|3413542_3414142_-	alpha/beta hydrolase	NA	NA	NA	NA
AZN65584.1\|3414154_3414796_-	glutathione S-transferase	NA	NA	NA	NA
AZN65585.1\|3414925_3415324_-	osmotically inducible protein C	NA	NA	NA	NA
AZN65586.1\|3415426_3416374_-	quercetin 2,3-dioxygenase	NA	NA	NA	NA
AZN65587.1\|3416757_3417759_+	DNA (cytosine-5-)-methyltransferase	E4WLM9	Ostreococcus_tauri_virus	5.9e-75	45.2
AZN65588.1\|3417825_3418962_+	restriction endonuclease	NA	NA	NA	NA
AZN65589.1\|3419121_3420690_-	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	2.6e-21	30.7
AZN65590.1\|3420837_3421173_-	DNA-binding protein	NA	NA	NA	NA
AZN65591.1\|3421975_3422620_+	cytochrome O ubiquinol oxidase	NA	NA	NA	NA
AZN65592.1\|3422616_3423210_-	threonine transporter RhtB	NA	NA	NA	NA
AZN65593.1\|3423424_3423814_-	hypothetical protein	NA	NA	NA	NA
AZN65594.1\|3423810_3424665_-	cobalamin biosynthesis protein CobQ	V5UP47	Mycobacterium_phage	2.5e-10	26.9
AZN65595.1\|3424750_3425143_-	invasion protein expression up-regulator SirB	NA	NA	NA	NA
AZN65596.1\|3425157_3425466_-	BolA family transcriptional regulator	NA	NA	NA	NA
AZN65597.1\|3426466_3426694_-	transcriptional regulator	S5MTW4	Brevibacillus_phage	9.0e-08	48.4
AZN65598.1\|3426807_3427017_+	hypothetical protein	NA	NA	NA	NA
AZN65599.1\|3427617_3428836_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	5.8e-77	51.9
AZN65600.1\|3429141_3432090_-	CRISPR-associated endonuclease Cas3''	NA	NA	NA	NA
AZN65601.1\|3432095_3433055_-	subtype I-F CRISPR-associated endonuclease Cas1	A0A2D0YFC9	Vibrio_phage	5.1e-52	38.6
AZN65602.1\|3433203_3434253_-	endonuclease	A0A2I2MUI7	uncultured_Caudovirales_phage	4.5e-78	63.0
AZN65603.1\|3434255_3434846_-	SAM-dependent methyltransferase	A0A2H4J5G6	uncultured_Caudovirales_phage	5.0e-34	85.0
AZN65604.1\|3434997_3435327_+	hypothetical protein	NA	NA	NA	NA
AZN65605.1\|3435426_3435741_+	hypothetical protein	NA	NA	NA	NA
AZN65606.1\|3435945_3437089_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN65607.1\|3437722_3438397_+	hypothetical protein	NA	NA	NA	NA
AZN65608.1\|3438396_3440670_+	hypothetical protein	NA	NA	NA	NA
AZN65609.1\|3440787_3441931_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN65610.1\|3443218_3444363_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.0e-15	27.4
AZN65611.1\|3447009_3448139_-\|transposase	IS3 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP022300

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP022300_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022300_1

4124-4196

Orphan

Consensus_repeat	Method
GTGAGACAAGTCCATCCGTATTAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022300_1

>merge|CP022300|1|4124-4196|CRISPRCasFinder
GTGAGACAAGTCCATCCGTATTACAGGCCAAAGAGGACGGCTTTAATGCGTGAGACAAGTCCGTCCGTATTAC

>CP022300|1|1|4124-4196|CRISPRCasFinder
GTGAGACAAGTCCATCCGTATTAC	AGGCCAAAGAGGACGGCTTTAATGC
GTGAGACAAGTCCGTCCGTATTAC

Protein	Signature genes	Signature genes Name	Protein_function
CP022300.1\|AZN65852.1\|9274_9589_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225794
CP022300.1\|AZN65855.1\|10739_11546_-\|catalytic-subunit-of-meta-cleavage-enzyme	unknown	unknown	gnl\|CDD\|153379
CP022300.1\|AZN65851.1\|8275_9262_-\|ferredoxin-NADP-reductase	unknown	unknown	gnl\|CDD\|99787
CP022300.1\|AZN65850.1\|7776_8184_+\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|131102
CP022300.1\|AZN65842.1\|413_1268_+\|resolvase	unknown	unknown	gnl\|CDD\|239737
CP022300.1\|AZN65854.1\|9931_10753_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP022300.1\|AZN65856.1\|11538_11814_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153392
CP022300.1\|AZN65849.1\|6784_7681_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|224151
CP022300.1\|AZN65843.1\|1347_1980_+\|peptide-transporter	unknown	unknown	gnl\|CDD\|222854
CP022300.1\|AZN65845.1\|2320_2644_+\|partition-protein	unknown	unknown	unknown
CP022300.1\|AZN65853.1\|9601_9922_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|239604
CP022300.1\|AZN65844.1\|2008_2233_+\|chromosome-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|370460
CP022300.1\|AZN65848.1\|6268_6781_-\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|173237
CP022300.1\|AZN65847.1\|4448_4700_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP022300.1\|AZN65852.1\|9274_9589_-\|hypothetical-protein	gnl\|CDD\|225794	COG3255, COG3255, Putative sterol carrier protein [Lipid metabolism].	2.74999e-09
CP022300.1\|AZN65855.1\|10739_11546_-\|catalytic-subunit-of-meta-cleavage-enzyme	gnl\|CDD\|153379	cd07367, CarBb, CarBb is the B subunit of the Class III Extradiol ring-cleavage dioxygenase, 2-aminophenol 1,6-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. CarBb is the B subunit of 2-aminophenol 1,6-dioxygenase (CarB), which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. It is a key enzyme in the carbazole degradation pathway isolated from bacterial strains with carbazole degradation ability. The enzyme is a heterotetramer composed of two A and two B subunits. CarB belongs to the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Although the enzyme was originally isolated as a meta-cleavage enzyme for 2'-aminobiphenyl-2,3-diol involved in carbazole degradation, it has also shown high specificity for 2,3-dihydroxybiphenyl.	1.68193e-127
CP022300.1\|AZN65851.1\|8275_9262_-\|ferredoxin-NADP-reductase	gnl\|CDD\|99787	cd06190, T4MO_e_transfer_like, Toluene-4-monoxygenase electron transfer component of Pseudomonas mendocina hydroxylates toluene and forms p-cresol as part of a three component toluene-4-monoxygenase system. Electron transfer is from NADH to an NADH:ferredoxin oxidoreductase (TmoF in P. mendocina) to ferredoxin to an iron-containing oxygenase. TmoF is homologous to other mono- and dioxygenase systems within the ferredoxin reductase family.	1.15776e-59
CP022300.1\|AZN65850.1\|7776_8184_+\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	gnl\|CDD\|131102	TIGR02047, putative_regulatory_protein, Cd(II)/Pb(II)-responsive transcriptional regulator. This model represents the cadmium(II) and/or lead(II) responsive transcriptional activator of the proteobacterial metal efflux system. This protein is a member of the MerR family of transcriptional activators (pfam00376) and contains a distinctive pattern of cysteine residues in its metal binding loop, Cys-X(6-9)-Cys, as well as a conserved and critical cysteine at the N-terminal end of the dimerization helix. [Regulatory functions, DNA interactions].	9.30224e-71
CP022300.1\|AZN65842.1\|413_1268_+\|resolvase	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	3.72511e-53
CP022300.1\|AZN65854.1\|9931_10753_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.72932e-37
CP022300.1\|AZN65856.1\|11538_11814_-\|hypothetical-protein	gnl\|CDD\|153392	cd07922, CarBa, CarBa is the A subunit of 2-aminophenol 1,6-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. CarBa is the A subunit of 2-aminophenol 1,6-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. 2-aminophenol 1,6-dioxygenase is a key enzyme in the carbazole degradation pathway isolated from bacterial strains with carbazole degradation ability. The enzyme is a heterotetramer composed of two A and two B subunits. CarB belongs to the class III extradiol dioxygenase family, composed of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Although the enzyme was originally isolated as a meta-cleavage enzyme for 2'-aminobiphenyl-2,3-diol involved in carbazole degradation, the enzyme has also shown high specificity for 2,3-dihydroxybiphenyl.	6.05421e-15
CP022300.1\|AZN65849.1\|6784_7681_-\|sodium:proton-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.7674e-30
CP022300.1\|AZN65843.1\|1347_1980_+\|peptide-transporter	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	1.20837e-67
CP022300.1\|AZN65853.1\|9601_9922_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|239604	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The ferredoxin component contains either a plant-type or Rieske-type [2Fe-2S] cluster. The Rieske ferredoxin component in this family carries an electron from the RO reductase component to the terminal RO oxygenase component. BPDO degrades biphenyls and polychlorinated biphenyls. BPDO ferredoxin (BphF) has structural features consistent with a minimal and perhaps archetypical Rieske protein in that the insertions that give other Rieske proteins unique structural features are missing. CARDO catalyzes dihydroxylation at the C1 and C9a positions of carbazole. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.	7.69617e-45
CP022300.1\|AZN65844.1\|2008_2233_+\|chromosome-partitioning-protein-ParB	gnl\|CDD\|370460	pfam09386, ParD, Antitoxin ParD. ParD is a plasmid anti-toxin than forms a ribbon-helix-helix DNA binding structure. It stabilizes plasmids by inhibiting ParE toxicity in cells that express ParD and ParE. ParD forms a dimer and also regulates its own promoter (parDE).	0.00256099
CP022300.1\|AZN65848.1\|6268_6781_-\|signal-peptidase-II	gnl\|CDD\|173237	PRK14776, PRK14776, lipoprotein signal peptidase; Provisional.	7.1602e-112

>CP022300.1|AZN65845.1|2320_2644_+|partition-protein
MIMDMNSVGVVGPAGFKELLAANSVQDTVIRCQDEGLVIALKVGGKDFVLGLSRGGVRYFRSFDAAASMLIQNGICRFESDLTGWHPRMFAKNKKGGNLLGSTGDEL
>CP022300.1|AZN65844.1|2008_2233_+|chromosome-partitioning-protein-ParB
MSKSISTLSAGRPSVRNDKAKAATLASLADDAGGMKRVNFELSPALHSKLKIYAAKQGMSIKELLTHYVDSLPE
>CP022300.1|AZN65843.1|1347_1980_+|peptide-transporter
MKVIAVLNQKGGSGKTTIATHLARALQLDGADVLLVDSDPQGSARDWAAVREDQPLTVVGIDRPTIDRDVKNVARKVDFVVIDGAPQAADLAVSAIKAADFILIPVQPSPYDIWATSDLVDLVKQRIELTDGKLQAAFVVSRAIKGTRIGSEVAEALAGYELPILDARITQRVSYPGTAAAGSTVMDAEPEGDAAKEIRALMAEIAQKLV
>CP022300.1|AZN65842.1|413_1268_+|resolvase
MNKNATTGLLLGYARVSTDDQDLTNQRAELQAAGCIKLFSEKITGTRRDRPELARMLDHLRPGDVVTVTRLDRLARSTRDLLNIAERIQGAGAGLRSLAEPWADTTTPAGRMVLTVFAGIAEFEHSLIIDRTRGGREAAKARGVKFGPKPTLTAAQIDHARELIDLEGRTVKETAALLGVHRSTLYRALERSEEVTLAEAKRRGAFREDALSEADAVAAVGDLVERQEEMPFFDDESGPSDDLPPPPYRTQSLPETLAALTDDELASWPGDFADEERARRQLLK
>CP022300.1|AZN65847.1|4448_4700_+|hypothetical-protein
MPVPAALDALGVYWKRDPDFVPVKDKMTVRLNVSLGGGVVELLATGPKWYDTRAEKGGGGAVDLAMHLLRLDFVNAVKRLQSN
>CP022300.1|AZN65848.1|6268_6781_-|signal-peptidase-II
MLIIGKKLSPYALLSMSGLLAASDQAVKWLVQQSMAYGEYVSVTPFFNWVHLWNTGAAFSLFANGGGWQRYFFIGIAVVVSIFLINLILENRHKGEAIAYSLILGGALGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLFVSSSLLGKKANTNAESDGSD
>CP022300.1|AZN65849.1|6784_7681_-|sodium:proton-antiporter
MSKSCGGACGGDATSAADTDIQASSEAPGRWVSVYAVPKMDCPSEERMIRLALNGFEEIRALSFDLSNRRLKVVHDGEVEPVTSKLKTLGLGASLQETVAANPETIKAAEFSAASAKQESGTLRWLLGINALLFVVEMTAGLIARSTGLIGESLDNFADAAVYGLALYAVGHSVKMQVRAAHLAGVLQLILAVGVLVEVVRRFVFGSEPESLVMMAIAFVALIANTSCLLLISKHREGGAHMKASWIFSANDVVINLGGITAGALVAWTGSNYPDLIIGTIAGGIVLNGARRILALKG
>CP022300.1|AZN65850.1|7776_8184_+|Cd(II)/Pb(II)-responsive-transcriptional-regulator
MRIGQLAQLVGVETQTIRFYEQQGLLPPPDRQDNGYRVYTEKHGEGLSFIRRCRILGLSLAEIHELQSYQDDPHQPCTAVNALLDDHISHVRSQITALQALEKQLVSLRASCNDDREVEACGVLAGISEGNMHQQ
>CP022300.1|AZN65851.1|8275_9262_-|ferredoxin-NADP-reductase
MPIIKINNNPISIQSSTDHSMLTDLLNAGIGYPYECVTGKCGLCKFELIQGNIIKTEENPTGLSSRDLKKGNRYLACKCKLNSDLDIKVKLDNKFIQKTKISKIRSSVISKELLTHDFIKITLKPDENMSWLPGQFCLLSDPLLPSIDRAYSIANNYIKDGHIDFYIKRVPDGIFSNHIFDKINIDSTLILKGPFGHSYYQRSNRKLLIIGGGSGLSYAASIAKQAFSEGKDFLFYYGSRSTQDIPNWSSLVFTNNEIIDIKTVLSQSNNEWTGPTGFLHEVVNEDLGASLCEFDIYLAGPPVMVECSIKSFFDQGVPSENIHYDSFY
>CP022300.1|AZN65852.1|9274_9589_-|hypothetical-protein
MNVTDLRQRITNSVGEDSGLNAKVKFDLGNNEVIFIDGISIPNNVHDSDIDSDITIKIKPENLTKILDKELNPKLAIMTGRMKLRGDIKIALRLDKVFGLEPSE
>CP022300.1|AZN65853.1|9601_9922_-|(2Fe-2S)-binding-protein
MNKKWVKACMESDILENSIFKFSRPGKSPIAIYRIEGKFYATEDTCTHGIASLSEGEIDGDVIECPFHGGAFNICTGEPESEPCTVALKTYQVDIVNNEVLILEEQ
>CP022300.1|AZN65854.1|9931_10753_-|alpha/beta-hydrolase
MKSIDYSEKYLNADGIETRYLEAGEGSPVILIHGGGAGAESEGNWKGVIPILAENFKVYAVDMIGFGKTAKPKIEYSQQIRTKHLVSFIKALGLEGKVSLVGNSMGGATALGVCVERPELVKNLVLMGSAGLVVELHEDLKPIVNYDFTETGMYKLVEALTNDDFQIDPKMVKKRVEYALDAETREAYASTMTWIKQQGGLFYPDEYIKKVKVPTLVVQGKEDKVVPITTAYKFLDLIEDSWGYIIPKCGHWAMIEHPTDFANATELFLKLRT
>CP022300.1|AZN65855.1|10739_11546_-|catalytic-subunit-of-meta-cleavage-enzyme
MANIVSSCATSHIVMSANGCEDQARNVIEGMKKLGNIIKKSKPDIILIISSDHMCNFDLSLQPRFAIGISDEYTTMGDMDIPIENIKGSRLLANTIVETADQDGFDLCQSEELKLDHGIMIPLTFMDLKNYPIVPLIVNINTSPMAEASRCVSLARTIKKSINELDEKLNISVIAAGGLSHWLCIENHGEVSEKFDHMIMDRLCNGEQEIITNMGNERIIQEGGNAGIEILTWLMASEISGNVSGEKIYYEPMRKWFTGVGGINFEVN
>CP022300.1|AZN65856.1|11538_11814_-|hypothetical-protein
MSNYKIDKIVQRIIKETQFREKLLENIDYLKELNLTNEEFNALVKAEPALLSAVGMHPILQMHYMMFRTPEIGIHVSVNDCLAIKNGDYHG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP022300_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022300_2

4842-4972

Orphan

Consensus_repeat	Method
AAATAAAGTTTGATCAAAAT	PILER-CR

2 spacers

The CRISPR arrays of CP022300_2

>merge|CP022300|2|4842-4972|PILER-CR
AAATAAAGTTTGATCAAAAAACCAGGCTTTTTAGATCAATTTGTGAACAACTTACAAATAAAGTTTGATCAAATTAGTAGCCGGCGACTCTCTACAGGGCCTTCCAGCTTAAAATAAAGTTTGATTAAAAT

>CP022300|2|1|4842-4972|PILER-CR
AAATAAAGTTTGATCAAAAA	ACCAGGCTTTTTAGATCAATTTGTGAACAACTTAC
AAATAAAGTTTGATCAAATT	AGTAGCCGGCGACTCTCTACAGGGCCTTCCAGCTTA
AAATAAAGTTTGATTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP022300.1\|AZN65852.1\|9274_9589_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225794
CP022300.1\|AZN65846.1\|2829_4176_+\|replication-protein	unknown	unknown	unknown
CP022300.1\|AZN65851.1\|8275_9262_-\|ferredoxin-NADP-reductase	unknown	unknown	gnl\|CDD\|99787
CP022300.1\|AZN65850.1\|7776_8184_+\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|131102
CP022300.1\|AZN65842.1\|413_1268_+\|resolvase	unknown	unknown	gnl\|CDD\|239737
CP022300.1\|AZN65854.1\|9931_10753_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP022300.1\|AZN65856.1\|11538_11814_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153392
CP022300.1\|AZN65849.1\|6784_7681_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|224151
CP022300.1\|AZN65843.1\|1347_1980_+\|peptide-transporter	unknown	unknown	gnl\|CDD\|222854
CP022300.1\|AZN65845.1\|2320_2644_+\|partition-protein	unknown	unknown	unknown
CP022300.1\|AZN65853.1\|9601_9922_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|239604
CP022300.1\|AZN65844.1\|2008_2233_+\|chromosome-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|370460
CP022300.1\|AZN65848.1\|6268_6781_-\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|173237
CP022300.1\|AZN65847.1\|4448_4700_+\|hypothetical-protein	unknown	unknown	unknown
CP022300.1\|AZN65855.1\|10739_11546_-\|catalytic-subunit-of-meta-cleavage-enzyme	unknown	unknown	gnl\|CDD\|153379
CP022300.1\|AZN65857.1\|11861_13019_-\|carbazole-dioxygenase	unknown	unknown	gnl\|CDD\|314565

Protein	Function_ID	Function_description	E-value
CP022300.1\|AZN65852.1\|9274_9589_-\|hypothetical-protein	gnl\|CDD\|225794	COG3255, COG3255, Putative sterol carrier protein [Lipid metabolism].	2.74999e-09
CP022300.1\|AZN65855.1\|10739_11546_-\|catalytic-subunit-of-meta-cleavage-enzyme	gnl\|CDD\|153379	cd07367, CarBb, CarBb is the B subunit of the Class III Extradiol ring-cleavage dioxygenase, 2-aminophenol 1,6-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. CarBb is the B subunit of 2-aminophenol 1,6-dioxygenase (CarB), which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. It is a key enzyme in the carbazole degradation pathway isolated from bacterial strains with carbazole degradation ability. The enzyme is a heterotetramer composed of two A and two B subunits. CarB belongs to the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Although the enzyme was originally isolated as a meta-cleavage enzyme for 2'-aminobiphenyl-2,3-diol involved in carbazole degradation, it has also shown high specificity for 2,3-dihydroxybiphenyl.	1.68193e-127
CP022300.1\|AZN65851.1\|8275_9262_-\|ferredoxin-NADP-reductase	gnl\|CDD\|99787	cd06190, T4MO_e_transfer_like, Toluene-4-monoxygenase electron transfer component of Pseudomonas mendocina hydroxylates toluene and forms p-cresol as part of a three component toluene-4-monoxygenase system. Electron transfer is from NADH to an NADH:ferredoxin oxidoreductase (TmoF in P. mendocina) to ferredoxin to an iron-containing oxygenase. TmoF is homologous to other mono- and dioxygenase systems within the ferredoxin reductase family.	1.15776e-59
CP022300.1\|AZN65850.1\|7776_8184_+\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	gnl\|CDD\|131102	TIGR02047, putative_regulatory_protein, Cd(II)/Pb(II)-responsive transcriptional regulator. This model represents the cadmium(II) and/or lead(II) responsive transcriptional activator of the proteobacterial metal efflux system. This protein is a member of the MerR family of transcriptional activators (pfam00376) and contains a distinctive pattern of cysteine residues in its metal binding loop, Cys-X(6-9)-Cys, as well as a conserved and critical cysteine at the N-terminal end of the dimerization helix. [Regulatory functions, DNA interactions].	9.30224e-71
CP022300.1\|AZN65842.1\|413_1268_+\|resolvase	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	3.72511e-53
CP022300.1\|AZN65854.1\|9931_10753_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.72932e-37
CP022300.1\|AZN65856.1\|11538_11814_-\|hypothetical-protein	gnl\|CDD\|153392	cd07922, CarBa, CarBa is the A subunit of 2-aminophenol 1,6-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. CarBa is the A subunit of 2-aminophenol 1,6-dioxygenase, which catalyzes the oxidization and subsequent ring-opening of 2-aminophenyl-2,3-diol. 2-aminophenol 1,6-dioxygenase is a key enzyme in the carbazole degradation pathway isolated from bacterial strains with carbazole degradation ability. The enzyme is a heterotetramer composed of two A and two B subunits. CarB belongs to the class III extradiol dioxygenase family, composed of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Although the enzyme was originally isolated as a meta-cleavage enzyme for 2'-aminobiphenyl-2,3-diol involved in carbazole degradation, the enzyme has also shown high specificity for 2,3-dihydroxybiphenyl.	6.05421e-15
CP022300.1\|AZN65849.1\|6784_7681_-\|sodium:proton-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.7674e-30
CP022300.1\|AZN65843.1\|1347_1980_+\|peptide-transporter	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	1.20837e-67
CP022300.1\|AZN65853.1\|9601_9922_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|239604	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The ferredoxin component contains either a plant-type or Rieske-type [2Fe-2S] cluster. The Rieske ferredoxin component in this family carries an electron from the RO reductase component to the terminal RO oxygenase component. BPDO degrades biphenyls and polychlorinated biphenyls. BPDO ferredoxin (BphF) has structural features consistent with a minimal and perhaps archetypical Rieske protein in that the insertions that give other Rieske proteins unique structural features are missing. CARDO catalyzes dihydroxylation at the C1 and C9a positions of carbazole. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.	7.69617e-45
CP022300.1\|AZN65844.1\|2008_2233_+\|chromosome-partitioning-protein-ParB	gnl\|CDD\|370460	pfam09386, ParD, Antitoxin ParD. ParD is a plasmid anti-toxin than forms a ribbon-helix-helix DNA binding structure. It stabilizes plasmids by inhibiting ParE toxicity in cells that express ParD and ParE. ParD forms a dimer and also regulates its own promoter (parDE).	0.00256099
CP022300.1\|AZN65848.1\|6268_6781_-\|signal-peptidase-II	gnl\|CDD\|173237	PRK14776, PRK14776, lipoprotein signal peptidase; Provisional.	7.1602e-112
CP022300.1\|AZN65857.1\|11861_13019_-\|carbazole-dioxygenase	gnl\|CDD\|314565	pfam11723, Aromatic_hydrox, Homotrimeric ring hydroxylase. This domain is found on aromatic hydroxylating enzymes such as 2-oxo-1,2-dihydroquinoline 8-monooxygenase from Pseudomonas putida and carbazole 1,9a-dioxygenase from Janthinobacterium. These enzymes are homotrimers and are distantly related to the typical oxygenase. This domain is found C terminal to the Rieske domain which binds an iron-sulphur cluster.	1.26521e-118

>CP022300.1|AZN65847.1|4448_4700_+|hypothetical-protein
MPVPAALDALGVYWKRDPDFVPVKDKMTVRLNVSLGGGVVELLATGPKWYDTRAEKGGGGAVDLAMHLLRLDFVNAVKRLQSN
>CP022300.1|AZN65846.1|2829_4176_+|replication-protein
MAVAQLALFDGAEEARAYHDPGRSGFFSILVDVNGDKRQSSHRLIEMPTVLGLIDKTRDTWLTQAEFIRPNRRVVNLARIGLLFADLDTYRIPGLTGRTPDALAASVLYHCHQEGIPTPSMLIFSGRGIQAKWLLDSPVPRQALPRWNACQKYLVDRLASVGADVGAKDASRVLRLVETVNTKSGEACRVVHVENGTDGQPIRYGFEYLAEVLLPVARWEIEQQRRERAERRQLKLLPGAKTDNLRGFSGRQLAWHRLEDLRKLATLRGGVGEGERMKHLFWRLNFLLLSGATHSGAMYHEATALARELAPHWNDYRSKELMTLYAKAKQYEAGEKISFGGKEYAPLYTPRNDTLISLFQITDAEQAELRTVISKGVARERDRKRKEGHRRAAGAVDRETYESQSASRQKPWEALGMSRASWYRAGKPLPASETSPSVLQAKEDGFNA
>CP022300.1|AZN65845.1|2320_2644_+|partition-protein
MIMDMNSVGVVGPAGFKELLAANSVQDTVIRCQDEGLVIALKVGGKDFVLGLSRGGVRYFRSFDAAASMLIQNGICRFESDLTGWHPRMFAKNKKGGNLLGSTGDEL
>CP022300.1|AZN65844.1|2008_2233_+|chromosome-partitioning-protein-ParB
MSKSISTLSAGRPSVRNDKAKAATLASLADDAGGMKRVNFELSPALHSKLKIYAAKQGMSIKELLTHYVDSLPE
>CP022300.1|AZN65843.1|1347_1980_+|peptide-transporter
MKVIAVLNQKGGSGKTTIATHLARALQLDGADVLLVDSDPQGSARDWAAVREDQPLTVVGIDRPTIDRDVKNVARKVDFVVIDGAPQAADLAVSAIKAADFILIPVQPSPYDIWATSDLVDLVKQRIELTDGKLQAAFVVSRAIKGTRIGSEVAEALAGYELPILDARITQRVSYPGTAAAGSTVMDAEPEGDAAKEIRALMAEIAQKLV
>CP022300.1|AZN65842.1|413_1268_+|resolvase
MNKNATTGLLLGYARVSTDDQDLTNQRAELQAAGCIKLFSEKITGTRRDRPELARMLDHLRPGDVVTVTRLDRLARSTRDLLNIAERIQGAGAGLRSLAEPWADTTTPAGRMVLTVFAGIAEFEHSLIIDRTRGGREAAKARGVKFGPKPTLTAAQIDHARELIDLEGRTVKETAALLGVHRSTLYRALERSEEVTLAEAKRRGAFREDALSEADAVAAVGDLVERQEEMPFFDDESGPSDDLPPPPYRTQSLPETLAALTDDELASWPGDFADEERARRQLLK
>CP022300.1|AZN65848.1|6268_6781_-|signal-peptidase-II
MLIIGKKLSPYALLSMSGLLAASDQAVKWLVQQSMAYGEYVSVTPFFNWVHLWNTGAAFSLFANGGGWQRYFFIGIAVVVSIFLINLILENRHKGEAIAYSLILGGALGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLFVSSSLLGKKANTNAESDGSD
>CP022300.1|AZN65849.1|6784_7681_-|sodium:proton-antiporter
MSKSCGGACGGDATSAADTDIQASSEAPGRWVSVYAVPKMDCPSEERMIRLALNGFEEIRALSFDLSNRRLKVVHDGEVEPVTSKLKTLGLGASLQETVAANPETIKAAEFSAASAKQESGTLRWLLGINALLFVVEMTAGLIARSTGLIGESLDNFADAAVYGLALYAVGHSVKMQVRAAHLAGVLQLILAVGVLVEVVRRFVFGSEPESLVMMAIAFVALIANTSCLLLISKHREGGAHMKASWIFSANDVVINLGGITAGALVAWTGSNYPDLIIGTIAGGIVLNGARRILALKG
>CP022300.1|AZN65850.1|7776_8184_+|Cd(II)/Pb(II)-responsive-transcriptional-regulator
MRIGQLAQLVGVETQTIRFYEQQGLLPPPDRQDNGYRVYTEKHGEGLSFIRRCRILGLSLAEIHELQSYQDDPHQPCTAVNALLDDHISHVRSQITALQALEKQLVSLRASCNDDREVEACGVLAGISEGNMHQQ
>CP022300.1|AZN65851.1|8275_9262_-|ferredoxin-NADP-reductase
MPIIKINNNPISIQSSTDHSMLTDLLNAGIGYPYECVTGKCGLCKFELIQGNIIKTEENPTGLSSRDLKKGNRYLACKCKLNSDLDIKVKLDNKFIQKTKISKIRSSVISKELLTHDFIKITLKPDENMSWLPGQFCLLSDPLLPSIDRAYSIANNYIKDGHIDFYIKRVPDGIFSNHIFDKINIDSTLILKGPFGHSYYQRSNRKLLIIGGGSGLSYAASIAKQAFSEGKDFLFYYGSRSTQDIPNWSSLVFTNNEIIDIKTVLSQSNNEWTGPTGFLHEVVNEDLGASLCEFDIYLAGPPVMVECSIKSFFDQGVPSENIHYDSFY
>CP022300.1|AZN65852.1|9274_9589_-|hypothetical-protein
MNVTDLRQRITNSVGEDSGLNAKVKFDLGNNEVIFIDGISIPNNVHDSDIDSDITIKIKPENLTKILDKELNPKLAIMTGRMKLRGDIKIALRLDKVFGLEPSE
>CP022300.1|AZN65853.1|9601_9922_-|(2Fe-2S)-binding-protein
MNKKWVKACMESDILENSIFKFSRPGKSPIAIYRIEGKFYATEDTCTHGIASLSEGEIDGDVIECPFHGGAFNICTGEPESEPCTVALKTYQVDIVNNEVLILEEQ
>CP022300.1|AZN65854.1|9931_10753_-|alpha/beta-hydrolase
MKSIDYSEKYLNADGIETRYLEAGEGSPVILIHGGGAGAESEGNWKGVIPILAENFKVYAVDMIGFGKTAKPKIEYSQQIRTKHLVSFIKALGLEGKVSLVGNSMGGATALGVCVERPELVKNLVLMGSAGLVVELHEDLKPIVNYDFTETGMYKLVEALTNDDFQIDPKMVKKRVEYALDAETREAYASTMTWIKQQGGLFYPDEYIKKVKVPTLVVQGKEDKVVPITTAYKFLDLIEDSWGYIIPKCGHWAMIEHPTDFANATELFLKLRT
>CP022300.1|AZN65855.1|10739_11546_-|catalytic-subunit-of-meta-cleavage-enzyme
MANIVSSCATSHIVMSANGCEDQARNVIEGMKKLGNIIKKSKPDIILIISSDHMCNFDLSLQPRFAIGISDEYTTMGDMDIPIENIKGSRLLANTIVETADQDGFDLCQSEELKLDHGIMIPLTFMDLKNYPIVPLIVNINTSPMAEASRCVSLARTIKKSINELDEKLNISVIAAGGLSHWLCIENHGEVSEKFDHMIMDRLCNGEQEIITNMGNERIIQEGGNAGIEILTWLMASEISGNVSGEKIYYEPMRKWFTGVGGINFEVN
>CP022300.1|AZN65856.1|11538_11814_-|hypothetical-protein
MSNYKIDKIVQRIIKETQFREKLLENIDYLKELNLTNEEFNALVKAEPALLSAVGMHPILQMHYMMFRTPEIGIHVSVNDCLAIKNGDYHG
>CP022300.1|AZN65857.1|11861_13019_-|carbazole-dioxygenase
MSNVSEDILKKVKGWPGYVDAKYGFRNHWYPVMFSKDIAEGEVKKIKLLGEPLLVKRIDGKLHCIKDRCLHRGVPLSEKLDCKTKDTITCWYHAWTYKWETGELCDIMTNPSSAQIGRHKLKVYPVEEAKNCVFIFLGDGEPHPLAHDTPPEFLDDGLEILGIAREVKSNWRLGVENGFDPSHIYIHKDSILVQGNDLVLPLGFAPGEDRSKQTKVIADDSEGGRKGVYDLIGDASVPVFEGTIDGELVREGNYGSTLVANNISIWLPGVLKVNPWPNHDMMQFEWYVPVDENTHIYFQTLGKKCETEEEIKAYEHSFDHKWKEMALIGFNDDDIWAREAMVDFYADDKGWVNEILFEPDEAIVEWRKLADKHNKGIQTLENIKG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP022300	Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence	4148-4172	0	1.0
CP022300_2	2.1\|4862\|35\|CP022300\|PILER-CR	4862-4896	35	NZ_CP022300	Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence	4862-4896	0	1.0
CP022300_2	2.2\|4917\|36\|CP022300\|PILER-CR	4917-4952	36	NZ_CP022300	Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence	4917-4952	0	1.0
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1165718-1165742	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1135758-1135782	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	1231941-1231965	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	738203-738227	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	854413-854437	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	376058-376082	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	453741-453765	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1306479-1306503	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	1078851-1078875	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1165724-1165748	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	567950-567974	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	556226-556250	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	150126-150150	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	561178-561202	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	553884-553908	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1220781-1220805	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	909601-909625	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	814726-814750	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	477005-477029	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1342675-1342699	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	706866-706890	6	0.76
CP022300_1	1.1\|4148\|25\|CP022300\|CRISPRCasFinder	4148-4172	25	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	577712-577736	6	0.76

1. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP022300 (Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence) position: , mismatch: 0, identity: 1.0

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggctttaatgc	Protospacer
*************************

2. spacer 2.1|4862|35|CP022300|PILER-CR matches to NZ_CP022300 (Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence) position: , mismatch: 0, identity: 1.0

accaggctttttagatcaatttgtgaacaacttac	CRISPR spacer
accaggctttttagatcaatttgtgaacaacttac	Protospacer
***********************************

3. spacer 2.2|4917|36|CP022300|PILER-CR matches to NZ_CP022300 (Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence) position: , mismatch: 0, identity: 1.0

agtagccggcgactctctacagggccttccagctta	CRISPR spacer
agtagccggcgactctctacagggccttccagctta	Protospacer
************************************

4. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

5. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

6. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

7. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

8. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

9. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

10. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

11. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

12. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

13. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

14. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

15. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

16. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

17. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

18. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

19. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

20. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

21. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

22. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

23. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

24. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

25. spacer 1.1|4148|25|CP022300|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.76

aggccaaagaggacggctttaatgc	CRISPR spacer
aggccaaagaggacggcttgtgaat	Protospacer
*******************  . ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. CP022299

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3291 : 70064

Leptospira_phage(25.0%)

transposase,integrase

attL 47104:47128|attR 66651:66675

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZN65763.1\|3291_4380_-\|transposase	IS3 family transposase	NA	NA	NA	NA
AZN65764.1\|4376_4739_-	hypothetical protein	NA	NA	NA	NA
AZN65765.1\|6313_6514_+	hypothetical protein	NA	NA	NA	NA
AZN65766.1\|6634_7312_+	hypothetical protein	NA	NA	NA	NA
AZN65767.1\|7308_12360_+	hypothetical protein	NA	NA	NA	NA
AZN65768.1\|13048_13294_+	hypothetical protein	NA	NA	NA	NA
AZN65769.1\|13406_13643_+	hypothetical protein	NA	NA	NA	NA
AZN65770.1\|13866_14618_-\|transposase	IS5/IS1182 family transposase	A0A0N9SHJ4	Paenibacillus_phage	6.0e-16	38.7
AZN65771.1\|14694_16362_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
AZN65772.1\|16765_17059_+	phenol hydroxylase	NA	NA	NA	NA
AZN65773.1\|17078_18083_+	phenol hydroxylase	NA	NA	NA	NA
AZN65774.1\|18094_18361_+	monooxygenase	NA	NA	NA	NA
AZN65775.1\|18409_19936_+	phenol 2-monooxygenase	NA	NA	NA	NA
AZN65776.1\|20053_20416_+	phenol hydroxylase	NA	NA	NA	NA
AZN65777.1\|20484_21546_+	phenol hydroxylase	NA	NA	NA	NA
AZN65778.1\|22770_23643_+	phenol degradation protein meta	NA	NA	NA	NA
AZN65779.1\|26069_27149_+	Rieske (2Fe-2S) protein	A0A076FFT9	Aureococcus_anophage	9.0e-13	33.6
AZN65780.1\|27222_28191_+	oxidoreductase	NA	NA	NA	NA
AZN65781.1\|29488_30454_+	oxidoreductase	NA	NA	NA	NA
AZN65782.1\|30471_31380_+	LysR family transcriptional regulator	A0A2H4J8I9	uncultured_Caudovirales_phage	4.4e-05	34.9
AZN65783.1\|31516_31918_-	transcriptional regulator	NA	NA	NA	NA
AZN65784.1\|31919_32210_-	hypothetical protein	NA	NA	NA	NA
AZN65785.1\|32842_33622_-	3-oxoadipate enol-lactonase	NA	NA	NA	NA
AZN65786.1\|33739_34945_-	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
AZN65787.1\|35074_35728_-	3-oxoadipate CoA-transferase	NA	NA	NA	NA
AZN65788.1\|35748_36420_-	3-oxoadipate CoA-transferase	NA	NA	NA	NA
AZN65789.1\|36621_36912_-	muconolactone delta-isomerase	NA	NA	NA	NA
AZN65790.1\|36926_38036_-	muconate cycloisomerase	NA	NA	NA	NA
AZN65791.1\|38137_39055_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZN65792.1\|39112_40726_-	dGTPase	NA	NA	NA	NA
AZN65793.1\|40722_41982_-	hypothetical protein	NA	NA	NA	NA
AZN65794.1\|42070_43015_-	catechol 1,2-dioxygenase	NA	NA	NA	NA
AZN65795.1\|46300_46519_-	hypothetical protein	NA	NA	NA	NA
AZN65796.1\|46523_47090_-	hypothetical protein	A0A2H4JBL5	uncultured_Caudovirales_phage	4.8e-26	33.5
47104:47128	attL	NA	NA	NA	NA
AZN65797.1\|47142_48362_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	3.4e-77	52.2
AZN65798.1\|48732_49932_+\|integrase	integrase	B7SYF8	Stenotrophomonas_phage	2.8e-39	28.8
AZN65840.1\|50026_50191_+	hypothetical protein	NA	NA	NA	NA
AZN65799.1\|50465_50717_-	hypothetical protein	NA	NA	NA	NA
AZN65800.1\|50911_51133_+	Cro/Cl family transcriptional regulator	NA	NA	NA	NA
AZN65801.1\|51346_52491_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.3e-13	27.7
AZN65802.1\|52743_54105_+	replication protein	Q4LAU7	Stenotrophomonas_phage	3.1e-18	30.5
AZN65803.1\|54094_54391_+	hypothetical protein	NA	NA	NA	NA
AZN65841.1\|54403_54580_+	hypothetical protein	NA	NA	NA	NA
AZN65804.1\|54601_54841_+	hypothetical protein	NA	NA	NA	NA
AZN65805.1\|54951_55947_+	hypothetical protein	NA	NA	NA	NA
AZN65806.1\|55946_56225_+	hypothetical protein	NA	NA	NA	NA
AZN65807.1\|56288_57119_+	hypothetical protein	NA	NA	NA	NA
AZN65808.1\|57173_58317_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.3e-13	27.7
AZN65809.1\|59297_59498_+	hypothetical protein	NA	NA	NA	NA
AZN65810.1\|59975_61119_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.3e-13	27.7
AZN65811.1\|61252_62047_+	2-keto-4-pentenoate hydratase	NA	NA	NA	NA
AZN65812.1\|62059_63013_+	acetaldehyde dehydrogenase (acetylating)	E5EQ71	Micromonas_sp._RCC1109_virus	1.1e-33	33.8
AZN65813.1\|63024_64065_+	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	7.7e-46	33.2
AZN65814.1\|64228_65083_+	5-carboxymethyl-2-hydroxymuconate isomerase	NA	NA	NA	NA
AZN65815.1\|66820_67261_+	hypothetical protein	NA	NA	NA	NA
66651:66675	attR	NA	NA	NA	NA
AZN65816.1\|67893_68523_-	hypothetical protein	NA	NA	NA	NA
AZN65817.1\|68729_70064_+\|transposase	ISNCY family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022301

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP022298

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP022300

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. CP022299

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection