CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025499	Lactobacillus paracasei subsp. tolerans strain 7112-2 chromosome, complete genome	1 crisprs	DinG,WYL,DEDDh,csa3,cas3,csn2,cas2,cas1,cas9	0	13	10	0
CP025498	Lactobacillus paracasei subsp. tolerans strain 7112-2 plasmid p7112201, complete sequence	0 crisprs	NA	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP025499_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025499_1

2269731-2271152

TypeII

Consensus_repeat	Method
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	PILER-CR
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CRISPRCasFinder
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CRT

21 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP025499_1

>merge|CP025499|1|2269731-2271152|PILER-CR,CRISPRCasFinder,CRT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGACTAACTTCTCGATGGATGTGTTAGGATAATAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACAACAACTTGGGATTTGATTGTTAAAGTCATGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTCCATGGTAAAAACCTCCTATTATTTTGTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTGTTGCAATCGGTGAAAGTATCGCGATTGCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACACTTGATCATGCAGAAGGATATTGACGAGTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCGACAATCTCCCGACTGATGATATTGGCCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCGATGTGTTCTTGTCAAAACATTTTTTGCGGCTCTTGAACTGATTGATTCGACATCTACCTGAGACAACATATTGATCAGCCTTTCTTCAACGATCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCCATAAAGTTGCTAATTCTAGAAATATTTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTGTCAGCCATAAGCGTGTTAGCCGCTACGAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCGAGACCAACACCAGCGCAAGCGAACGCTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCGCGAGTTGATCGCAACGGAAGGCAGTTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCCAGTTGTTTAATGGATAAGCCTCTGATAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTTCGTCTTTAAGCGGTGCTAACCAATTTGGGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGGTTTCTTCGTTTACAATCGTGCCGCGATCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCGGTCAACTGTTGTGCGGTTTCATCAGTGCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACAGTGAGCCGGTGCATATTGCACCGGCTTTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTGGTAATGGGTCGTCCGCATTATGATATTCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCAGTAGATAAGATTGTTTTTGTCAAGTTTCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGGGGTGATTTGTTGCATACCCACAATGTCAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCCGTCTAAGCTGTTGTTCTGGAGAAAACAGCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

>CP025499|1|1|2269731-2271152|PILER-CR
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TAACTTCTCGATGGATGTGTTAGGATAATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACAACTTGGGATTTGATTGTTAAAGTCAT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TCCATGGTAAAAACCTCCTATTATTTTGTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTTGCAATCGGTGAAAGTATCGCGATTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	ACTTGATCATGCAGAAGGATATTGACGAGT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGACAATCTCCCGACTGATGATATTGGCC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGATGTGTTCTTGTCAAAACATTTTTTGCG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACATATTGATCAGCCTTTCTTCAACGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CCATAAAGTTGCTAATTCTAGAAATATTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTCAGCCATAAGCGTGTTAGCCGCTACGA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGAGACCAACACCAGCGCAAGCGAACGCTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGCGAGTTGATCGCAACGGAAGGCAGTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCAGTTGTTTAATGGATAAGCCTCTGATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TTCGTCTTTAAGCGGTGCTAACCAATTTGG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGTTTCTTCGTTTACAATCGTGCCGCGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGGTCAACTGTTGTGCGGTTTCATCAGTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AGTGAGCCGGTGCATATTGCACCGGCTTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGGTAATGGGTCGTCCGCATTATGATATTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CAGTAGATAAGATTGTTTTTGTCAAGTTTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGGGTGATTTGTTGCATACCCACAATGTCA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCGTCTAAGCTGTTGTTCTGGAGAAAACA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

>CP025499|1|1|2269731-2271152|CRISPRCasFinder
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TAACTTCTCGATGGATGTGTTAGGATAATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACAACTTGGGATTTGATTGTTAAAGTCAT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TCCATGGTAAAAACCTCCTATTATTTTGTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTTGCAATCGGTGAAAGTATCGCGATTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	ACTTGATCATGCAGAAGGATATTGACGAGT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGACAATCTCCCGACTGATGATATTGGCC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGATGTGTTCTTGTCAAAACATTTTTTGCG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACATATTGATCAGCCTTTCTTCAACGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CCATAAAGTTGCTAATTCTAGAAATATTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTCAGCCATAAGCGTGTTAGCCGCTACGA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGAGACCAACACCAGCGCAAGCGAACGCTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGCGAGTTGATCGCAACGGAAGGCAGTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCAGTTGTTTAATGGATAAGCCTCTGATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TTCGTCTTTAAGCGGTGCTAACCAATTTGG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGTTTCTTCGTTTACAATCGTGCCGCGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGGTCAACTGTTGTGCGGTTTCATCAGTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AGTGAGCCGGTGCATATTGCACCGGCTTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGGTAATGGGTCGTCCGCATTATGATATTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CAGTAGATAAGATTGTTTTTGTCAAGTTTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGGGTGATTTGTTGCATACCCACAATGTCA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCGTCTAAGCTGTTGTTCTGGAGAAAACA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

>CP025499|1|1|2269731-2271152|CRT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TAACTTCTCGATGGATGTGTTAGGATAATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACAACTTGGGATTTGATTGTTAAAGTCAT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TCCATGGTAAAAACCTCCTATTATTTTGTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTTGCAATCGGTGAAAGTATCGCGATTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	ACTTGATCATGCAGAAGGATATTGACGAGT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGACAATCTCCCGACTGATGATATTGGCC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGATGTGTTCTTGTCAAAACATTTTTTGCG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACATATTGATCAGCCTTTCTTCAACGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CCATAAAGTTGCTAATTCTAGAAATATTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTCAGCCATAAGCGTGTTAGCCGCTACGA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGAGACCAACACCAGCGCAAGCGAACGCTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGCGAGTTGATCGCAACGGAAGGCAGTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCAGTTGTTTAATGGATAAGCCTCTGATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TTCGTCTTTAAGCGGTGCTAACCAATTTGG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGTTTCTTCGTTTACAATCGTGCCGCGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGGTCAACTGTTGTGCGGTTTCATCAGTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AGTGAGCCGGTGCATATTGCACCGGCTTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGGTAATGGGTCGTCCGCATTATGATATTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CAGTAGATAAGATTGTTTTTGTCAAGTTTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGGGTGATTTGTTGCATACCCACAATGTCA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCGTCTAAGCTGTTGTTCTGGAGAAAACA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP025499.1\|AZP99536.1\|2265753_2267445_-\|cytochrome-BD-biosynthesis-protein	unknown	unknown	gnl\|CDD\|227321
CP025499.1\|AZP99540.1\|2271176_2271854_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
CP025499.1\|AZP99532.1\|2259221_2260670_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|236580
CP025499.1\|AZP99545.1\|2278279_2279446_-\|hypothetical-protein	unknown	unknown	unknown
CP025499.1\|AZP99538.1\|2268442_2268694_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|225511
CP025499.1\|AZP99531.1\|2258528_2259095_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP025499.1\|AZP99535.1\|2264125_2265757_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
CP025499.1\|AZP99549.1\|2282340_2284083_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|227321
CP025499.1\|AZP99547.1\|2280237_2280561_+\|hypothetical-protein	unknown	unknown	unknown
CP025499.1\|AZP99548.1\|2280632_2282360_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
CP025499.1\|AZP99530.1\|2258373_2258523_-\|acetyltransferase	unknown	unknown	unknown
CP025499.1\|AZP99533.1\|2260840_2262679_-\|PTS-beta-glucoside-transporter-subunit-EIIBCA	unknown	unknown	gnl\|CDD\|273919
CP025499.1\|AZP99542.1\|2272133_2273039_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP025499.1\|AZP99546.1\|2279675_2280044_+\|DUF1093-domain-containing-protein	unknown	unknown	gnl\|CDD\|377665
CP025499.1\|AZP99543.1\|2273236_2277322_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
CP025499.1\|AZP99544.1\|2277484_2278279_-\|hypothetical-protein	unknown	unknown	unknown
CP025499.1\|AZP99539.1\|2268699_2269590_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222853
CP025499.1\|AZP99534.1\|2263130_2263988_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|170086
CP025499.1\|AZP99537.1\|2267641_2268067_-\|NusG-domain-II-containing-protein	unknown	unknown	gnl\|CDD\|227646
CP025499.1\|AZP99541.1\|2271850_2272156_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043

Protein	Function_ID	Function_description	E-value
CP025499.1\|AZP99536.1\|2265753_2267445_-\|cytochrome-BD-biosynthesis-protein	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	1.47636e-93
CP025499.1\|AZP99540.1\|2271176_2271854_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	8.55728e-83
CP025499.1\|AZP99532.1\|2259221_2260670_-\|6-phospho-beta-glucosidase	gnl\|CDD\|236580	PRK09593, arb, 6-phospho-beta-glucosidase; Reviewed.	0
CP025499.1\|AZP99546.1\|2279675_2280044_+\|DUF1093-domain-containing-protein	gnl\|CDD\|377665	pfam06486, DUF1093, Protein of unknown function (DUF1093). This family consists of several hypothetical bacterial proteins of unknown function.	4.09197e-19
CP025499.1\|AZP99538.1\|2268442_2268694_+\|IS3-family-transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.47634e-08
CP025499.1\|AZP99531.1\|2258528_2259095_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.00337e-11
CP025499.1\|AZP99535.1\|2264125_2265757_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.53157e-92
CP025499.1\|AZP99549.1\|2282340_2284083_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
CP025499.1\|AZP99548.1\|2280632_2282360_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	7.03579e-159
CP025499.1\|AZP99533.1\|2260840_2262679_-\|PTS-beta-glucoside-transporter-subunit-EIIBCA	gnl\|CDD\|273919	TIGR01995, beta-glucosides_PTS_EIIBCA, PTS system, beta-glucoside-specific IIABC component. This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.	0
CP025499.1\|AZP99542.1\|2272133_2273039_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.76359e-89
CP025499.1\|AZP99543.1\|2273236_2277322_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	5.52985e-120
CP025499.1\|AZP99539.1\|2268699_2269590_+\|hypothetical-protein	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.70628e-141
CP025499.1\|AZP99534.1\|2263130_2263988_-\|PRD-domain-containing-protein	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	3.39686e-35
CP025499.1\|AZP99537.1\|2267641_2268067_-\|NusG-domain-II-containing-protein	gnl\|CDD\|227646	COG5341, COG5341, Uncharacterized protein conserved in bacteria [Function unknown].	4.87983e-33
CP025499.1\|AZP99541.1\|2271850_2272156_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.69699e-23

>CP025499.1|AZP99539.1|2268699_2269590_+|hypothetical-protein
MFDYIHQESHHHQVTKMCRILGVSRAQYYRYRSPKPSKRRAEDVDLKQRILRIFAEFKQRYGVMKIHHELNLELQPLQLRCSPRRISRLMKELDIHSVTVNKWKAASASKTKVEQRPNLLKQDFSTTGLNQKWTADMTYIQTKRHGWCYLSTIMDLHSRRIIGYSFSKKMDTDLVLKALESAVKNRTITGDLIIHTDLGSQYTSDDYNQRLTELHIRHSYSRKGCPYDNAPMESFHASLKKECVYPVPVFEDYETAAAVLFEYVHAFYNRKRIHSSLGYQTPLQVEIATLTSQMAA
>CP025499.1|AZP99538.1|2268442_2268694_+|IS3-family-transposase
MPTRYDKEFKQNIINLYKQGESAAQLAREYGIGYSTVHKWIQGQAKTQSGKSPDEIKAMEKRLASLSEENEILKKALGFLAQK
>CP025499.1|AZP99537.1|2267641_2268067_-|NusG-domain-II-containing-protein
MRWLKKYVRPFDYVIVIVLFVACFLPVGIFSLTEANVNTNQKVAVISIKGHVKRRIQLTTHTRHQQFTLYPAKGQYNIIEVQGARIRDKEDNSPDQIAVHTGWISQVGQQSICLPHKLLIEIKPAQAGTGTSGDTGGLVHP
>CP025499.1|AZP99536.1|2265753_2267445_-|cytochrome-BD-biosynthesis-protein
MLGLLKYGRDQRWAGVIETVFDWLPTLLPIMIALNFAAKRPGNALIITVILVLIWLGYVIGYERHHRHAWAMSAKRELRDHYFEALYQRNNAGDATAADNAVIQRDLGGLNNLDMFYSTLFPTLIQAGLTFLLLIGLSVWYGSWLAFLPLVCVFLIGFAMMFLGKKMSAQNKAHLAGFLRMGGRFMNDLSGMNTLVMYNAADRYAKKFADDSEYFRQATMNLLRTQLQVLFVINGFVYLTVFAGGFVTALQLAAGQLPAAGAFATWFALAMMMVNARQLGYFFHVVKSNGPALAGILATIAKSKTTPATVKITDNRPLKQLVLQDVAIGYEADAPLVSDINATLVPGKLYGLAGENGTGKSTLTQALLGQLTPLSGTIMADNTPVTALSNAQRAAVFGYVAANDYIFSGTIKENLLLGNQFGDQWQQHLDELGLMHFVTDLQDGYATEVGEGGRLLSPGQRQQLAFARMLLADKTVYLLDEMTSSIDAANAAIILAAIKRLSRQKIVLFISHDLSAMAEADVVWFIHDHQLISADHAQLYRDQPAYRHLVDNPEAMLKEGQPS
>CP025499.1|AZP99535.1|2264125_2265757_-|ABC-transporter-ATP-binding-protein
MIRSLLRYTHHLTGTIIISFLIGLVAELTKVVVLVLAAMMLFDPQNASHLLIPGIIAVVIVGLGSFGEQYAGHFVAFHVLAELRGAVYRKLMQLAPAKLDSQGSGKLLKLIGSDIEAMEIFYAHTIVPVAIGLIYGVLMVAVYSSLNGPAAAVVLVSYAAVGLLIPYYRHEQMTAKAQAADRQKAVNQQYLLESVRGMAVLRQLEVADARMKTGNEGFDHEATAFQQSQFGQLLKNMSATLVMLLAWLFIVWLSGWTQPQPLQQALLAVFPLTFGPLLALTNLPASLLNGFAAARNLLNLLQEAPATSAAIDATQTLNQIAIIQVDHVTFKYPSRDETVLRQVSLSLHAGEIVGFVGASGSGKSTLAKLIMGWYPLTQGRILIDGIDVTKIDPASLRAQVNYLPQTPVFFSESVRDNLTLHDLTITDAQIWTVLDQVKLTSRLRQAEKGLDENVVSGQLQFSSGEQQRLELARALLHPSSVLVLDEPTSNLDTENERLILDTIKAYYHGIVIMISHRAESAAYADRLYRFADHRVSAASTEPK
>CP025499.1|AZP99534.1|2263130_2263988_-|PRD-domain-containing-protein
MIIQNVLNNNAVVARHQQREVIVVERGIGFRAKKDAKMALRDSMKVYVPEDQAKLKIATATIASLPSAYLDLAAGIIQEAEKRLQTTFNSYLLIELADHVHFAVQRLHEKIVLHNKLLWEIQVAYTQEYEMGEWALHQIAAQLHEQLPEDEAGFIALKFVSNDLNHQQTVNSLAFTQTLASLTKIIFYNLGLDMNVKTPDYQRLVIHLKFFLQRMYAAAPSPLSLKMENYDYVLLKHLQQDYARAYHCMEDVDRFMQQKLAIAIPKNEQIYLTMHIARLAKSFAE
>CP025499.1|AZP99533.1|2260840_2262679_-|PTS-beta-glucoside-transporter-subunit-EIIBCA
MNESGLAQQLLNLIGGKQNINQVWHCATRLRFTLKDRAKVPKDKIEALDGVITVVEASGQFQVVIGNNVGDVYHEVVKLEPSLSEGETSGETAAQGKMTFKSAFNSLLTFISGVFTPFLGAMAGAGILKGLLSLAVVMGWLTAKSGAYQIWWAAADGIFYFLPIALAFTAAKQLKVNQFVSMAIAAAMVSPGIVALGAKATTIDFFGIPVVPANYTATVLPILLVVVVQKFLEPVFNKLWHESVRNIMAPLCLLVVIVPLTLIVVGPISATVSSWLATAIVSLNKSVPILAGLVLGGFWQVIVIFGVHWALVPVMMNNIAQNGTDLMMPILLPAVLSQAGAALAVFLRTRDAKMKSLAGSSTITALFGITEPTIYGITLKLKKPFYLACVAGAVGGMIVAISGAGANAAALASVLSLPTFIGKGFGLSVVGDVVAFALGTVLTYFFGGINAGAKAKTAPSVNSEPGEALAAPVKGVLVPLTGLADEVFASETMGKGVAIVPENGIVKAPVAGVIRLLYPTGHAIGIQSDKGSEILIHIGIDAVNLKGKHFQPLVAQGQHVEIGTPLVQFDHEAIEKEGYESTVMMIVTNSDQYQIATLGQGATDDRPVMTLA
>CP025499.1|AZP99532.1|2259221_2260670_-|6-phospho-beta-glucosidase
MTYLNFPKNFLWGGATAANQLEGAYQEDGKGLSIADVLPQGKDRFTIVNRPDFNWTIDKSKYRYPNHQGIDHYHRFKEDIKLFSEMGFKCYRFSIAWSRIFPEGDEKTPNASGLKFYDEVIATCLKYDIEPVVTISHYEMPLHLVTKYGGWKNKRLIEFYKHFAETVLTRYFKQVKYWMTFNEINSAWAFPVMSQGLVANNGGNDKQTIFQAWHNQFVASAWAVKIGHALDPKLQVGCMLLYATTYGYDANPVNQLATLQQNQAFNFFCGDVQVRGEYPAYTDALMADNGFKFTDLDFSAEELTLLKNHPVDYIGFSYYMSAVVETVEKEHAEVGGNLLSGIKNPFLKASEWGWQIDPIGLRIALNQLYERYRKPLFIVENGLGAVDKPDADGKIKDDYRIDYLKQHIEQMGAAIHDGLDLMGYTPWGCIDLVSASSGQMSKRYGFIYVDLDDAGQGSLNRYKKQSFNWYQRVIASNGTDLG
>CP025499.1|AZP99531.1|2258528_2259095_-|TetR/AcrR-family-transcriptional-regulator
MDTREKLVATAASLFQKEGVRATGLAQILTVSGTPKGSLYYYFPNGKAQLIEAAITYAGQHILEHVQQDLDRYKAPDAALAGQLESMATEMQEKGHLGGNSISLIALETGDDPELQAACSAVFTQLETLYIKKLTSAGIPPDRAQPLGQFIQASIEGAIILAATKNNPDLLRQTADQLTRLIKLALAA
>CP025499.1|AZP99530.1|2258373_2258523_-|acetyltransferase
MPVVCFYHLTRSPAQQPQCKDLGRNGQSATITPKATYTAVANRAGSRSL
>CP025499.1|AZP99540.1|2271176_2271854_-|type-II-A-CRISPR-associated-protein-Csn2
MNLAYYPFQLITTKPSEVTVIDTASPKVLTDLIEALRNDLDKVVLSNDQLEPQEIRKASLWIGDPMLELDLDKLFQRLIYKRMELLIENQRLVELIDQSQQMAMYLLQDPFLSDLPVTVEPGGKLEQIMKYCNVHFDEAVTTESTSKIEALIQTLTKLEEKKLVILTNVSHYLSARDFSSVTEQIGDTELQVVLIEFSKVNRKKYFEKCQYIYIDEDFVDNRELD
>CP025499.1|AZP99541.1|2271850_2272156_-|CRISPR-associated-endonuclease-Cas2
MRLMIMFDLPVLTSENRRNYRKFRKALINEGFLMMQYSIYVRVCSTKKSAEFLEHRIAAMKPPIGTVQTLMVTEAQYQAMHFLVGEAKQDIRNSADRTVII
>CP025499.1|AZP99542.1|2272133_2273039_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRSLIVTQHCKVTTKNRTLVVQTDGEVNNVPIEDINQVVFTTTRALLSADAITTLAEANAKVIFSGRDGQPVTETTNLYSDRRKADLVRLQVNWPKSLVENLWTKIVAAKVSNQAQVTKLCGFDNQSLLDDLDTLEINDRSNREATAARKYFKLIFGDDFSRSDICATNAALNYGYSILLSTTNRAIVSAGHITEIGMHHSSVANQYNLGSDLMEPFRPAIDYWVANQKFTDLTPNIKYGLIALLNLEVTFNGKKALLQNALDEHVENCLAYLDGKRNNCRIEVEFPNEVSSDAFNDHV
>CP025499.1|AZP99543.1|2273236_2277322_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTKLGKPYGIGVDIGSNSIGFAAVDENSHLIRLKGKTVIGARLFEEGKAAADRRASRTTRRRLSRNRWRLSFLRDFFESHITPTGPNFFMRQKYSEISPKDKARYKYEKRLFNDRTDAEFYQQYPTMYHLRNRLLTDPSKADVREIYFAIHHILKSRGHFLTSGYAKDFNTNKVALNEIFPALQDAYAQVYPDLDITFDENKVNEFKTVLLNEKATPSDTQRALVNLLLAEDGDKDILKQQKQVLTEFAKAVVGLKTKLNVALGTEVDSSEATVWNFSLGQLDDKWAGIESAMTDEGTEILDQIRDLYRARLLNGIVPAGKTLSQAKVDDYAQHHEDLELFKDYLKQLEDDGTAKAIRQLYDRYIDGDDAKPFVREDFVKALTKEVTAHPNAKSPELLERLAQPDFMLKQRNKANGAIPVQMQQRELDQIIKNQSVYYDWLAAPNPVEKHRKSMPYQLDELLNFRIPYYVGPLVTAKEQKAAQGGVFAWMVRKDPDGNITPYNFDEKVDREASANTFIQRMKTTDTYLIGEDVLPKQSLLYQRYEVLNELNNVRVNNEKLSIEQKQQVIRELFERHNSVTIKQFAENLRAHGDYAHIPEIRGLADEKRFLSSLSTYRQLKSLLPDAIDDPAKQADIENIIAWSTVFEDAAIFKTKLKEINWLDSQTITKLSNIRYRGWGQFSHKFLNGLTLGNGHTIIQELFLSNNNLMQILTDETLQKKMTELNADKLKAANINDAIDDAYTSPSNKKALRQVLRVIEDIKRAADGQDPSWLYVETADGGGTPGKRTRARQHQLQEIYANAAHELIDSAVRGELEDKIADKADFNDRLVLYFMQGGRDIYTGTPLNIDQLSSYDIDHILPQSLIKDNSLDNRVLVHAIINREKNATFASTIYAQKMNATWRQWHEAGLISGRKLRNLQMRPDQIDKYASGFVARQLVETRQIIKLTEQIVAAQYPETKIIAVKAGLSHQLREELEFPKNRDVNHYHHAFDAFLAARIGTYLLKRFPNLQAFFTYGKFKKADVKKLRGFNFIRDITHAEDKIVVKDTGEVIWDKKRDVDELDRIYNFKRMLITHEVHFEKADLFKQTVYGAKDSKEAGGKKQLISKKKGYPVDIYGGYTQETGSYLSVVRLTKKAMYAVVKVSTRDAAKLAVAKSISEQKENETLNDIIDEKLSKISKNGKITHELFEVVLPRVGQKTLFKNSKYNLFLVNSDTYMHNYQELWMPREYQKMWKDISLSKYGDAQTEDQLDQIFGFIVSQVNSYFNLYDINQFRKKLNDAADKFATLPMRDTDDMQGKIATIGQLLIGLQANAARSDLRNLDIKTPLGLLQIPNGISLDSDTSVVYQSPTGLLEREVHLSDL
>CP025499.1|AZP99544.1|2277484_2278279_-|hypothetical-protein
MEATKLAKRKQWPVPFSQTEPHFTFNNWLKFFSVVLFTYLLFYTRNPIGGFFNMSGTTFLNVANGWTRAVVVFGGVLYCAIIFAGAVWAAGWDGLSQLFASFRWRDIWYVFAYGILYLIATTLGGILGDLVPIRFGVDFVNTLEAAQFGNLGAFSLISFRAFFMTLATQLTAVMIFLASQQLFSRLAIKHRRWALFLTYLLALAVTAVVTTTPLAPHVFVNIASGLVAQLPLYWVYRRSRNILVVTLSAFILMHVMIGLAVMLG
>CP025499.1|AZP99545.1|2278279_2279446_-|hypothetical-protein
MSRQNLMILIVDLVLIIIFIGGFGWGIGTVKRYQVEPNTSRTETNTDSLYSESRFEKTLKKFKRLDLMVRLGPVKDAKTFNYTPDEFNVKYSSQPIVPGLKATKTLNAETGEVEVCTTMTPQGVTVAGDYLLTTAYDHDGFHNSVMYIQDLKTGKLLNTVVLNGRPHVGGLTYDAKNDNIWICGRRNNAAEVFAIKLKTALTYNVDKKAKAVAYSQRAQLGNISRASFVTYYENALFVGFFNPTGKGNIQRYPLNDKGQVVGKSLTSSISNQFDVLTQSVLHQDILSKIQGMAFYGDYTILSQSYGGGNSMLYIFKTDPKKTIFRASDAIDTFDMPSHLEQISTHDGRMYMMFESAAYAYRHRSTNQLDRVLSMNLEGFVQLVLKEEK
>CP025499.1|AZP99546.1|2279675_2280044_+|DUF1093-domain-containing-protein
MKKILIGIGIFIGLVILGGAGFYAWYTQSTPYYTQITTTGKKFDVIDDETGAPRDIDYAYTQMAYDEKGHGTEVDFNGHKSRPLKMQAYLRLDYSTRRNQVISWEAVPKEKVPKAALAKLNR
>CP025499.1|AZP99547.1|2280237_2280561_+|hypothetical-protein
MTNEHKVLRGLSYISVIFAPILFPILVWIFTPQGSVTRDTAKHALWLHIIPTLLSIFIFMIIGGVGFFTNSINATSAVSLILLLVAMVVDIGMVVYNIYTGIKIITS
>CP025499.1|AZP99548.1|2280632_2282360_-|thiol-reductant-ABC-exporter-subunit-CydC
MHWLKNEHWVRPDLKRYRGLLFWSLILGIMTFVFAGALMFTSGFLIDKSATKPLFAAIYVTVVLTRAFGIGRPVFQYIERLTSHNWVLRITSHMRRKLYKVLETDAAFVSEHHQTGDILGLLADDIGHIQNLYLRMIFPTVVGAGLTVIATLLLGWFNWGFALWIMLLLLFQVLILPWWGLVVERFRKAEQKQLNHDAYVSLTDSVLGLSDWVITHREKDFMSQSLAAPKKLAASTVKSKRFQWRRDFVGQLLFVLIVISMLIWTNLEWTGNQASANWVGAFVLVVFPLDQAFSGIAQGVGEWPTYRDAIRHLNDLQPVTRQLPQQQAVPTQFKEMTLQHLSFQYTPKDPELITDIDLTVHSGEKIAILGPSGMGKTTLLQLVLGDLTPTTGNVLIDGQDVLTYQQHRTNLFAVLDQSPFLFNTSIVNNVRLGNEQASDADVAAALKAVKLDQLVAQLPNGINSSVEEAGFGFSGGERQRLSLARILLQDAPIVLLDEPTVGLDPITEQALLETMFTVLQGKTILWVTHHLQGVNQTDRVIFLEDGRLTMNDTPSHLAKNDERYQNLYALDAGLR
>CP025499.1|AZP99549.1|2282340_2284083_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKTLMRLSGMKRIMTMLAGFALVQAFVILLQGKFLAEGIVHSWNRQSLAGLWLPLGLFATAFVIRQLIVWVRNRIGARFAMTSSAWLQAQLLKHLYALGPAAVAKEGTCNLVTMALDGIPEAENYIELILNKILNMSIIPWVLVAYIWYENWLTGFTLLIMFPIIILFMVILGLAAQDKSESQYAGFQKMSNHFIDSLRGLKTLQLMGISRQYVNNVYDVSEDYRKQTMGVLRIAMLSTFALDFFTTLSIAVVAVFLGIKLMDGTIPLYPAMVALILAPEYFMPIRDFGTDYHATLNGKNAMKAIWQVIDQPLPTDTNVLPAFSRWRAQDTVTINHLDFTYPNERAGIQNANLQFTGTEKVAIIGASGSGKSTLLNLIGGFLQPQKAAMTVRGTKVPHMTQAAWQDHLSYIPQDPYLFADTITANIRFYRPDASDEDVKQAAEAAGLSHWIETLADGYATRIGEGGRGISGGQAQRIALARTLIDTNRSIWLFDEPTAHLDIETEAELKETLVPLFKNRLVIFATHRLHWLNQMDRVIVVDGGKIIAEGTPSELAAHSKPYQALVHEMRGEFNALVEK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025499_1	1.21\|2271087\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271087-2271116	30	NZ_CP031181	Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_G, complete sequence	1301-1330	0	1.0
CP025499_1	1.21\|2271087\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271087-2271116	30	NZ_CP046668	Lactobacillus plantarum strain 83-18 plasmid p83-18.8, complete sequence	2173-2202	0	1.0
CP025499_1	1.21\|2271087\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271087-2271116	30	NC_019233	Lactobacillus rennini plasmid pREN, complete sequence	3859-3888	0	1.0
CP025499_1	1.20\|2271021\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271021-2271050	30	NZ_CP017904	Vibrio alginolyticus strain K05K4 plasmid pL289, complete sequence	152941-152970	5	0.833
CP025499_1	1.20\|2271021\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271021-2271050	30	NZ_CP017901	Vibrio alginolyticus strain K04M5 plasmid pL294, complete sequence	158597-158626	5	0.833
CP025499_1	1.20\|2271021\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271021-2271050	30	NZ_CP017909	Vibrio alginolyticus strain K06K5 plasmid pL291, complete sequence	155161-155190	5	0.833
CP025499_1	1.20\|2271021\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271021-2271050	30	NZ_CP017893	Vibrio alginolyticus strain K04M1 plasmid pL280, complete sequence	136535-136564	5	0.833
CP025499_1	1.20\|2271021\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2271021-2271050	30	NZ_CP017898	Vibrio alginolyticus isolate K04M3 plasmid pL294, complete sequence	157962-157991	5	0.833
CP025499_1	1.3\|2269899\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269899-2269928	30	NZ_CP021954	Klebsiella pneumoniae strain AR_0148 plasmid tig00001025alt_u_pilon, complete sequence	7530-7559	6	0.8
CP025499_1	1.3\|2269899\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269899-2269928	30	KJ801817	Enterococcus phage ECP3, complete genome	49229-49258	6	0.8
CP025499_1	1.3\|2269899\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269899-2269928	30	AP018715	Enterococcus phage phiM1EF22 DNA, complete sequence	47479-47508	6	0.8
CP025499_1	1.3\|2269899\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269899-2269928	30	AP018714	Enterococcus phage phiEF17H DNA, complete sequence	49325-49354	6	0.8
CP025499_1	1.4\|2269965\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269965-2269994	30	MT074431	Salmonella phage demigod, complete genome	324-353	6	0.8
CP025499_1	1.4\|2269965\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269965-2269994	30	NC_023608	Salmonella phage vB_SenS-Ent2 complete genome	38327-38356	6	0.8
CP025499_1	1.5\|2270031\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270031-2270060	30	NZ_CP053710	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence	156078-156107	6	0.8
CP025499_1	1.5\|2270031\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270031-2270060	30	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	127368-127397	6	0.8
CP025499_1	1.8\|2270229\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270229-2270258	30	NZ_CP025942	Bacillus subtilis strain BJ3-2 plasmid unnamed, complete sequence	14925-14954	6	0.8
CP025499_1	1.8\|2270229\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270229-2270258	30	NZ_CP032854	Bacillus subtilis subsp. subtilis strain MH-1 plasmid unnamed1, complete sequence	22350-22379	6	0.8
CP025499_1	1.11\|2270427\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270427-2270456	30	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	37361-37390	6	0.8
CP025499_1	1.17\|2270823\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270823-2270852	30	NZ_CP020740	[Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence	44625-44654	6	0.8
CP025499_1	1.15\|2270691\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270691-2270720	30	NZ_CP025810	Sulfitobacter sp. SK025 plasmid unnamed2, complete sequence	57180-57209	7	0.767
CP025499_1	1.19\|2270955\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270955-2270984	30	NZ_CP042825	Rhizobium sp. WL3 plasmid unnamed2, complete sequence	467711-467740	7	0.767
CP025499_1	1.19\|2270955\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270955-2270984	30	NZ_CP015630	Borrelia turicatae strain BTE5EL plasmid lp159	26021-26050	7	0.767
CP025499_1	1.6\|2270097\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270097-2270126	30	NZ_CP030832	Neorhizobium sp. NCHU2750 plasmid pNCHU2750d, complete sequence	25343-25372	8	0.733
CP025499_1	1.9\|2270295\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270295-2270324	30	AP014435	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22C-MedDCM-OCT-S41-C155, * SEQUENCING IN PROGRESS *, 2 ordered pieces	10947-10976	8	0.733
CP025499_1	1.9\|2270295\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270295-2270324	30	AP013443	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22C-MedDCM-OCT-S23-C7	19838-19867	8	0.733
CP025499_1	1.9\|2270295\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270295-2270324	30	AP014428	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S29-C101, * SEQUENCING IN PROGRESS *, 7 ordered pieces	8798-8827	8	0.733
CP025499_1	1.9\|2270295\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270295-2270324	30	NZ_CP015354	Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence	45187-45216	8	0.733
CP025499_1	1.13\|2270559\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270559-2270588	30	NC_015062	Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence	582633-582662	8	0.733
CP025499_1	1.15\|2270691\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270691-2270720	30	NZ_CP046917	Paraburkholderia sp. DHF22 plasmid p1, complete sequence	140954-140983	8	0.733
CP025499_1	1.17\|2270823\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270823-2270852	30	MH576968	Streptomyces phage Wofford, complete genome	99312-99341	8	0.733
CP025499_1	1.17\|2270823\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270823-2270852	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	447964-447993	8	0.733
CP025499_1	1.19\|2270955\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270955-2270984	30	MT028491	Ochrobactrum phage vB_OspM_OC, complete genome	7390-7419	8	0.733
CP025499_1	1.19\|2270955\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270955-2270984	30	MK288021	Bacillus phage pW2, complete genome	66366-66395	8	0.733
CP025499_1	1.3\|2269899\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2269899-2269928	30	LR135896	uncultured phage genomic DNA containing rbcL region region	22390-22419	9	0.7
CP025499_1	1.5\|2270031\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270031-2270060	30	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	598353-598382	10	0.667
CP025499_1	1.5\|2270031\|30\|CP025499\|PILER-CR,CRISPRCasFinder,CRT	2270031-2270060	30	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	1044313-1044342	10	0.667

1. spacer 1.21|2271087|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031181 (Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_G, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtctaagctgttgttctggagaaaaca	CRISPR spacer
gccgtctaagctgttgttctggagaaaaca	Protospacer
******************************

2. spacer 1.21|2271087|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046668 (Lactobacillus plantarum strain 83-18 plasmid p83-18.8, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtctaagctgttgttctggagaaaaca	CRISPR spacer
gccgtctaagctgttgttctggagaaaaca	Protospacer
******************************

3. spacer 1.21|2271087|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NC_019233 (Lactobacillus rennini plasmid pREN, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtctaagctgttgttctggagaaaaca	CRISPR spacer
gccgtctaagctgttgttctggagaaaaca	Protospacer
******************************

4. spacer 1.20|2271021|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017904 (Vibrio alginolyticus strain K05K4 plasmid pL289, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

5. spacer 1.20|2271021|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017901 (Vibrio alginolyticus strain K04M5 plasmid pL294, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

6. spacer 1.20|2271021|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017909 (Vibrio alginolyticus strain K06K5 plasmid pL291, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

7. spacer 1.20|2271021|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017893 (Vibrio alginolyticus strain K04M1 plasmid pL280, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

8. spacer 1.20|2271021|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017898 (Vibrio alginolyticus isolate K04M3 plasmid pL294, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

9. spacer 1.3|2269899|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021954 (Klebsiella pneumoniae strain AR_0148 plasmid tig00001025alt_u_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tccatggtaaaaacctcctattattttgtt	CRISPR spacer
tctaacataaaaatctccttttattttgtt	Protospacer
**.*  .******.***** **********

10. spacer 1.3|2269899|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to KJ801817 (Enterococcus phage ECP3, complete genome) position: , mismatch: 6, identity: 0.8

-tccatggtaaaaacctcctattattttgtt	CRISPR spacer
acccatta-aaaaacctcctactattttgta	Protospacer
 .**** . ************.********

11. spacer 1.3|2269899|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to AP018715 (Enterococcus phage phiM1EF22 DNA, complete sequence) position: , mismatch: 6, identity: 0.8

-tccatggtaaaaacctcctattattttgtt	CRISPR spacer
acccatta-aaaaacctcctactattttgta	Protospacer
 .**** . ************.********

12. spacer 1.3|2269899|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to AP018714 (Enterococcus phage phiEF17H DNA, complete sequence) position: , mismatch: 6, identity: 0.8

-tccatggtaaaaacctcctattattttgtt	CRISPR spacer
acccatta-aaaaacctcctactattttgta	Protospacer
 .**** . ************.********

13. spacer 1.4|2269965|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to MT074431 (Salmonella phage demigod, complete genome) position: , mismatch: 6, identity: 0.8

tgttgcaatcggtgaaagtatcgcgattgc	CRISPR spacer
tgttgcattcggtgaaagtgtcgctttttg	Protospacer
******* ***********.****  **

14. spacer 1.4|2269965|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NC_023608 (Salmonella phage vB_SenS-Ent2 complete genome) position: , mismatch: 6, identity: 0.8

tgttgcaatcggtgaaagtatcgcgattgc	CRISPR spacer
tgttgcattcggtgaaagtgtcgctttttg	Protospacer
******* ***********.****  **

15. spacer 1.5|2270031|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053710 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
acgtcgtggtgcagaaggatatagacgagt	Protospacer
** * .* .************* *******

16. spacer 1.5|2270031|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
acgtcgtggtgcagaaggatgttgacgagt	Protospacer
** * .* .***********.*********

17. spacer 1.8|2270229|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025942 (Bacillus subtilis strain BJ3-2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

aacatattgatcagcctttct--tcaacgatc	CRISPR spacer
accatattgatcagcatttcttctcaatgg--	Protospacer
* ************* *****  ****.*.

18. spacer 1.8|2270229|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032854 (Bacillus subtilis subsp. subtilis strain MH-1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

aacatattgatcagcctttct--tcaacgatc	CRISPR spacer
accatattgatcagcatttcttctcaatgg--	Protospacer
* ************* *****  ****.*.

19. spacer 1.11|2270427|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 6, identity: 0.8

cgagaccaacaccagcgcaagcgaacgctt	CRISPR spacer
gaagaccaacaccagcgcaagcgcaagcaa	Protospacer
 .********************* * **

20. spacer 1.17|2270823|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020740 ([Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence) position: , mismatch: 6, identity: 0.8

agtgagccggtgcatattgcaccggctttt	CRISPR spacer
gatcggccggcgcatattgcgccggctttt	Protospacer
..* .*****.*********.*********

21. spacer 1.15|2270691|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025810 (Sulfitobacter sp. SK025 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

ggtttcttcgtttacaatcgtgccgcgatc	CRISPR spacer
tgcttcttcatttaccatcgtgccgcgcgg	Protospacer
 *.******.***** ***********

22. spacer 1.19|2270955|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042825 (Rhizobium sp. WL3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
tcgtaaatatgattgtttttgtcaagataa	Protospacer
. ***.*** **************** *

23. spacer 1.19|2270955|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015630 (Borrelia turicatae strain BTE5EL plasmid lp159) position: , mismatch: 7, identity: 0.767

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
ctgttgataagattgtttttgccaaatgat	Protospacer
* ** ****************.***.*  .

24. spacer 1.6|2270097|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030832 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750d, complete sequence) position: , mismatch: 8, identity: 0.733

gcgacaatctcccgactgatgatattggcc	CRISPR spacer
ccgcggatctcccgaccgatgatattgaag	Protospacer
 **  .**********.**********.

25. spacer 1.9|2270295|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to AP014435 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22C-MedDCM-OCT-S41-C155, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
tggttggtttgctaattctaaaaatatttt	Protospacer
. .* .. ************.*********

26. spacer 1.9|2270295|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to AP013443 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22C-MedDCM-OCT-S23-C7) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
tggttggtttgctaattctaaaaatatttt	Protospacer
. .* .. ************.*********

27. spacer 1.9|2270295|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to AP014428 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S29-C101, *** SEQUENCING IN PROGRESS ***, 7 ordered pieces) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
tggttggtttgctaattctaaaaatatttt	Protospacer
. .* .. ************.*********

28. spacer 1.9|2270295|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015354 (Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
aaataaagttggtaatactagaaatgtgaa	Protospacer
  ********* **** ********.*

29. spacer 1.13|2270559|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NC_015062 (Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence) position: , mismatch: 8, identity: 0.733

gccagttgtttaatggataagcctctgata	CRISPR spacer
cccagttgtttaatggatacggcttattga	Protospacer
 ****************** * **.    *

30. spacer 1.15|2270691|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046917 (Paraburkholderia sp. DHF22 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtttcttcgtttacaatcgtgccgcgatc	CRISPR spacer
cgagccgacgttgacaatcgtgccgcgatt	Protospacer
 *  .*  **** ****************.

31. spacer 1.17|2270823|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to MH576968 (Streptomyces phage Wofford, complete genome) position: , mismatch: 8, identity: 0.733

agtgagccggtgcatattgcaccggctttt	CRISPR spacer
gactggccggtgcttattgcaccggcctta	Protospacer
... .******** ************.**

32. spacer 1.17|2270823|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 8, identity: 0.733

agtgagccggtgcatattgcaccggctttt	CRISPR spacer
tattttccggggcatattgtaccggctttc	Protospacer
 .*   **** ********.*********.

33. spacer 1.19|2270955|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to MT028491 (Ochrobactrum phage vB_OspM_OC, complete genome) position: , mismatch: 8, identity: 0.733

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
agatggataagattgtcattgtcaagttct	Protospacer
 ..*.***********. **********..

34. spacer 1.19|2270955|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to MK288021 (Bacillus phage pW2, complete genome) position: , mismatch: 8, identity: 0.733

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
tcatctatactattgtttttgtcaagtttg	Protospacer
. .*  ***  ******************

35. spacer 1.3|2269899|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to LR135896 (uncultured phage genomic DNA containing rbcL region region) position: , mismatch: 9, identity: 0.7

tccatggtaaaaacctcctattattttgtt	CRISPR spacer
gatatggtaaaagccttctattatttccgc	Protospacer
  .*********.***.*********.  .

36. spacer 1.5|2270031|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 10, identity: 0.667

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
gtcgcgccatgcagaatgatattgacgatg	Protospacer
...  ..********* ***********

37. spacer 1.5|2270031|30|CP025499|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 10, identity: 0.667

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
gtcgcgccatgcagaatgatattgacgatg	Protospacer
...  ..********* ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

337535 : 397356

Staphylococcus_phage(40.0%)

transposase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP97729.1\|337535_338225_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AZQ00272.1\|338450_338975_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AZP97730.1\|339057_339447_-	DUF1093 domain-containing protein	NA	NA	NA	NA
AZP97731.1\|339478_340003_-	hypothetical protein	NA	NA	NA	NA
AZP97732.1\|339992_340262_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
AZP97733.1\|340369_341785_+\|transposase	IS5 family transposase ISLca2	NA	NA	NA	NA
AZP97734.1\|342210_342936_-	rhodopsin	NA	NA	NA	NA
AZP97735.1\|342935_343616_-	hypothetical protein	NA	NA	NA	NA
AZP97736.1\|343605_344394_-	hypothetical protein	NA	NA	NA	NA
AZP97737.1\|344844_346371_+	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	7.4e-53	31.3
AZP97738.1\|346641_347763_+	PRD domain-containing protein	NA	NA	NA	NA
AZQ00273.1\|347755_348724_+	PTS fructose transporter subunit IIA	NA	NA	NA	NA
AZP97739.1\|348724_349036_+	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
AZP97740.1\|349177_350464_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
AZP97741.1\|350480_350903_+	hypothetical protein	NA	NA	NA	NA
AZP97742.1\|350924_351785_+	ketose-bisphosphate aldolase	NA	NA	NA	NA
AZP97743.1\|351897_352539_+	kinase	NA	NA	NA	NA
AZP97744.1\|352825_353656_+	transcriptional regulator	NA	NA	NA	NA
AZP97745.1\|353648_354518_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
AZP97746.1\|354557_355553_+	ornithine cyclodeaminase family protein	NA	NA	NA	NA
AZP97747.1\|356107_356887_+	alpha/beta hydrolase	A0A291AV30	Mycobacterium_phage	1.0e-05	25.4
AZP97748.1\|357157_357412_+	hypothetical protein	NA	NA	NA	NA
AZP97749.1\|358140_358875_+	hypothetical protein	NA	NA	NA	NA
AZP97750.1\|358781_359780_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.8e-55	39.8
AZP97751.1\|359742_359928_-	hypothetical protein	NA	NA	NA	NA
AZP97752.1\|360503_361358_+	formylglycine-generating enzyme family protein	A0A075BSL8	Microcystis_phage	8.4e-14	29.2
AZQ00274.1\|361360_362140_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
AZP97753.1\|362152_363277_+	radical SAM/SPASM domain-containing protein	NA	NA	NA	NA
AZP97754.1\|363624_364560_+	ribonucleoside hydrolase RihC	NA	NA	NA	NA
AZP97755.1\|364571_365978_+	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
AZP97756.1\|365993_366491_+	N-acetyltransferase	NA	NA	NA	NA
AZP97757.1\|366533_367274_+	GntR family transcriptional regulator	NA	NA	NA	NA
AZP97758.1\|367418_368216_-	protein SipE	NA	NA	NA	NA
AZP97759.1\|368226_369069_-	PTS fructose transporter subunit IID	NA	NA	NA	NA
AZP97760.1\|369072_369840_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AZP97761.1\|369865_370375_-	PTS mannose/fructose/sorbose transporter subunit IIB	NA	NA	NA	NA
AZP97762.1\|370402_370810_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
AZP97763.1\|371104_373843_+	PRD domain-containing protein	NA	NA	NA	NA
AZP97764.1\|373884_375180_+	RNA polymerase sigma-54 factor	NA	NA	NA	NA
AZP97765.1\|375589_377047_+	PRD domain-containing protein	NA	NA	NA	NA
AZP97766.1\|377048_377519_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
AZP97767.1\|377520_378462_+	ketose-bisphosphate aldolase	NA	NA	NA	NA
AZP97768.1\|378491_378965_+	PTS fructose transporter subunit IIA	NA	NA	NA	NA
AZP97769.1\|378961_379279_+	PTS fructose transporter subunit IIB	NA	NA	NA	NA
AZP97770.1\|379294_380380_+	PTS fructose transporter subunit IIC	NA	NA	NA	NA
AZP97771.1\|380402_381377_+	DUF4432 domain-containing protein	NA	NA	NA	NA
AZP97772.1\|381383_382070_+	D-lyxose/D-mannose family sugar isomerase	NA	NA	NA	NA
AZP97773.1\|382188_383655_+	xylulokinase	NA	NA	NA	NA
AZP97774.1\|383814_384813_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.5e-49	38.4
AZP97775.1\|384956_385400_+	PTS fructose transporter subunit IIA	NA	NA	NA	NA
AZP97776.1\|385439_386984_+	PTS subunit IIBC	NA	NA	NA	NA
AZP97777.1\|387048_388215_+	putative C-S lyase	NA	NA	NA	NA
AZP97778.1\|388216_389941_+	HTH domain-containing protein	NA	NA	NA	NA
AZP97779.1\|390295_392161_+	PRD domain-containing protein	NA	NA	NA	NA
AZP97780.1\|392150_393017_+	ketose-bisphosphate aldolase	NA	NA	NA	NA
AZP97781.1\|393056_395000_+	PTS fructose transporter subunit IIA	NA	NA	NA	NA
AZP97782.1\|395227_395425_+	hypothetical protein	NA	NA	NA	NA
AZP97783.1\|395399_395753_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
AZP97784.1\|395853_397356_+\|transposase	IS66 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

541969 : 565427

Lactobacillus_phage(68.42%)

transposase,integrase

attL 534639:534653|attR 569751:569765

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
534639:534653	attL	NA	NA	NA	NA
AZP97905.1\|541969_542899_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	5.9e-106	63.7
AZP97906.1\|543092_543638_-	hydrophobic protein	NA	NA	NA	NA
AZP97907.1\|543958_545128_-\|integrase	site-specific integrase	Q6J1W6	Lactobacillus_phage	6.6e-219	98.2
AZP97908.1\|545240_545501_-	hypothetical protein	B4XYT0	Lactobacillus_phage	2.5e-09	40.7
AZP97909.1\|545590_546211_+	hypothetical protein	NA	NA	NA	NA
AZP97910.1\|546194_546431_-	hypothetical protein	NA	NA	NA	NA
AZP97911.1\|546431_546539_-	hypothetical protein	NA	NA	NA	NA
AZP97912.1\|546623_547331_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
AZP97913.1\|547489_547912_-	ImmA/IrrE family metallo-endopeptidase	A0A0P0IJN5	Lactobacillus_phage	7.8e-21	39.1
AZP97914.1\|547904_548258_-	XRE family transcriptional regulator	A0A141E1M3	Streptococcus_phage	7.7e-14	40.9
AZP97915.1\|548501_548750_+	hypothetical protein	A0A0P0ID24	Lactobacillus_phage	2.7e-37	97.5
AZP97916.1\|548791_548992_+	hypothetical protein	NA	NA	NA	NA
AZP97917.1\|548962_549796_-	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	2.8e-46	37.8
AZP97918.1\|549856_550615_+	hypothetical protein	A0A1B0YEA7	Lactobacillus_phage	1.9e-41	49.4
AZP97919.1\|550615_550795_+	hypothetical protein	NA	NA	NA	NA
AZP97920.1\|550787_551039_-	DUF1883 domain-containing protein	NA	NA	NA	NA
AZP97921.1\|551104_551461_+	DUF771 domain-containing protein	U5U4L9	Lactobacillus_phage	2.0e-62	98.3
AZP97922.1\|551460_551553_+	hypothetical protein	A0A0P0IZE0	Lactobacillus_phage	4.5e-11	96.7
AZP97923.1\|551545_551749_+	hypothetical protein	NA	NA	NA	NA
AZP97924.1\|551731_552277_-	hypothetical protein	NA	NA	NA	NA
AZP97925.1\|552457_552772_+	hypothetical protein	NA	NA	NA	NA
AZP97926.1\|552764_553511_+	DnaD domain protein	A0A0N7IRA7	Lactobacillus_phage	5.8e-35	56.1
AZP97927.1\|553525_554350_+	DNA replication protein	A0A0P0I3L9	Lactobacillus_phage	9.6e-116	74.7
AZP97928.1\|554349_554868_+	DNA polymerase III subunit epsilon	NA	NA	NA	NA
AZP97929.1\|554914_555337_+	replication terminator protein	NA	NA	NA	NA
AZP97930.1\|555338_556076_+	hypothetical protein	A0A097BY87	Enterococcus_phage	1.3e-47	43.0
AZP97931.1\|556087_556375_+	hypothetical protein	Q8LTA8	Lactobacillus_phage	1.6e-38	76.8
AZP97932.1\|556444_556777_+	hypothetical protein	NA	NA	NA	NA
AZP97933.1\|557291_557735_+	transcriptional regulator	A0A0P0IZI6	Lactobacillus_phage	1.2e-77	97.3
AZP97934.1\|558079_558277_+	hypothetical protein	NA	NA	NA	NA
AZP97935.1\|558248_558902_+	hypothetical protein	NA	NA	NA	NA
AZP97936.1\|558971_559190_+	hypothetical protein	NA	NA	NA	NA
AZP97937.1\|559152_560151_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-55	39.8
AZP97938.1\|560346_560565_-	CsbD family protein	NA	NA	NA	NA
AZP97939.1\|562097_562433_+	ribonucleoside-diphosphate reductase	A0A0N7IRA2	Lactobacillus_phage	6.8e-52	90.6
AZP97940.1\|562429_562540_+	hypothetical protein	NA	NA	NA	NA
AZP97941.1\|562552_562885_+\|transposase	transposase	NA	NA	NA	NA
AZP97942.1\|562914_563643_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	7.6e-32	40.1
AZP97943.1\|563687_564518_+\|transposase	transposase	NA	NA	NA	NA
AZP97944.1\|564563_565427_+\|transposase	transposase	Q6J1X2	Lactobacillus_phage	3.1e-24	30.5
569751:569765	attR	NA	NA	NA	NA

DBSCAN-SWA_3

594676 : 619284

Lactobacillus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP97976.1\|594676_595464_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP97977.1\|595831_596104_-	hypothetical protein	NA	NA	NA	NA
AZP97978.1\|596163_598968_-	magnesium-transporting ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	1.5e-72	27.6
AZP97979.1\|599509_600193_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	3.1e-59	51.3
AZP97980.1\|600667_601822_+	cation:proton antiporter	NA	NA	NA	NA
AZP97981.1\|601830_602618_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP97982.1\|602767_603388_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.9e-56	52.9
AZP97983.1\|603575_604505_-	mannose-6-phosphate isomerase	NA	NA	NA	NA
AZP97984.1\|604518_605349_-	PTS fructose transporter subunit IID	NA	NA	NA	NA
AZP97985.1\|605361_606216_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AZP97986.1\|606244_606739_-	PTS mannose/fructose/sorbose transporter subunit IIB	NA	NA	NA	NA
AZP97987.1\|606782_607202_-	PTS N'-diacetylchitobiose transporter subunit IIA	NA	NA	NA	NA
AZP97988.1\|607378_608101_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
AZP97989.1\|608198_608936_+	GntR family transcriptional regulator	NA	NA	NA	NA
AZP97990.1\|609240_609561_+	hypothetical protein	NA	NA	NA	NA
AZP97991.1\|609657_610245_+	recombinase family protein	M4QQC6	Vibrio_phage	1.0e-18	42.3
AZP97992.1\|610379_611741_+	MFS transporter	NA	NA	NA	NA
AZP97993.1\|611941_612499_+	hypothetical protein	NA	NA	NA	NA
AZP97994.1\|613020_613808_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP97995.1\|615011_615233_-\|transposase	IS3 family transposase	NA	NA	NA	NA
AZP97996.1\|615275_615407_-\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	2.3e-16	90.7
AZQ00282.1\|615487_615670_+	hypothetical protein	NA	NA	NA	NA
AZP97997.1\|615663_616581_+	FAD:protein FMN transferase	NA	NA	NA	NA
AZP97998.1\|616727_617336_+	NADPH-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.8e-50	52.8
AZP97999.1\|617346_618615_+	NADPH-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.8e-49	47.7
AZP98000.1\|618888_619020_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	2.3e-16	90.7
AZP98001.1\|619062_619284_+\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

879172 : 971825

101

Lactobacillus_phage(90.74%)

portal,integrase,capsid,holin,head,protease,transposase,tRNA,tail,terminase

attL 888339:888357|attR 967808:967826

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP98230.1\|879172_880675_+\|transposase	IS66 family transposase	NA	NA	NA	NA
AZP98231.1\|880969_881518_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AZP98232.1\|881897_883616_+	APC family permease	NA	NA	NA	NA
AZP98233.1\|883902_885111_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
AZP98234.1\|885113_886142_+	glycosyltransferase	NA	NA	NA	NA
AZP98235.1\|886154_887168_+	lysylphosphatidylglycerol synthetase family protein	NA	NA	NA	NA
AZP98236.1\|887203_887557_+	hypothetical protein	NA	NA	NA	NA
AZP98237.1\|887642_888818_-	aromatic amino acid aminotransferase	NA	NA	NA	NA
888339:888357	attL	NA	NA	NA	NA
AZP98238.1\|889063_889342_+	DUF1797 domain-containing protein	NA	NA	NA	NA
AZP98239.1\|889326_889467_-	hypothetical protein	NA	NA	NA	NA
AZP98240.1\|889572_891666_+	LTA synthase family protein	W6LM83	Streptococcus_phage	6.1e-151	46.9
AZP98241.1\|891858_892299_+	transcriptional repressor	NA	NA	NA	NA
AZP98242.1\|898358_899006_-	hypothetical protein	NA	NA	NA	NA
AZP98243.1\|899186_900371_+	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.5e-141	66.0
AZP98244.1\|900484_901978_+	MFS transporter	NA	NA	NA	NA
AZP98245.1\|902072_902543_-	MerR family transcriptional regulator	NA	NA	NA	NA
AZP98246.1\|902786_904265_+	MFS transporter	NA	NA	NA	NA
AZP98247.1\|904261_904987_+	DUF4811 domain-containing protein	NA	NA	NA	NA
AZP98248.1\|905087_905771_-	phosphatase PAP2 family protein	NA	NA	NA	NA
AZP98249.1\|905746_905944_+	alpha-galactosidase	NA	NA	NA	NA
AZP98250.1\|906349_908761_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	68.4
AZP98251.1\|908829_908940_+	hypothetical protein	NA	NA	NA	NA
AZP98252.1\|909026_910670_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
AZP98253.1\|910674_911385_+	16S rRNA pseudouridine(516) synthase	NA	NA	NA	NA
AZP98254.1\|911527_911743_+	DNA-binding protein	NA	NA	NA	NA
AZP98255.1\|911859_912681_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
AZP98256.1\|912677_913181_-	NUDIX domain-containing protein	NA	NA	NA	NA
AZP98257.1\|913504_914644_-\|integrase	site-specific integrase	A0A0P0IXL3	Lactobacillus_phage	2.4e-218	100.0
AZP98258.1\|914761_915829_-\|protease	CAAX protease	A0A0N7IRA5	Lactobacillus_phage	1.1e-207	100.0
AZP98259.1\|915973_916405_-	hypothetical protein	A0A0P0IJV8	Lactobacillus_phage	6.8e-73	100.0
AZP98260.1\|916474_916957_-	hypothetical protein	A0A0P0IZP3	Lactobacillus_phage	2.1e-83	100.0
AZP98261.1\|916960_917254_-	hypothetical protein	A0A0P0HRW5	Lactobacillus_phage	5.7e-47	100.0
AZP98262.1\|917437_918298_-	ImmA/IrrE family metallo-endopeptidase	A0A0P0IV64	Lactobacillus_phage	2.8e-158	100.0
AZP98263.1\|918284_918653_-	transcriptional regulator	A0A0P0I3L3	Lactobacillus_phage	2.8e-59	100.0
AZP98264.1\|918908_919106_+	hypothetical protein	A0A0P0IK60	Lactobacillus_phage	5.2e-28	100.0
AZP98265.1\|919102_919825_+	phage regulatory protein	A0A0P0IDD0	Lactobacillus_phage	1.4e-126	100.0
AZP98266.1\|919832_920045_+	hypothetical protein	A0A0N7IRA6	Lactobacillus_phage	7.8e-30	100.0
AZP98267.1\|920153_920378_+	DUF771 domain-containing protein	A0A0P0IQT9	Lactobacillus_phage	2.6e-39	100.0
AZP98268.1\|920377_920470_+	hypothetical protein	A0A0P0I7S8	Lactobacillus_phage	1.2e-11	100.0
AZP98269.1\|920466_920679_+	hypothetical protein	A0A0P0IXL9	Lactobacillus_phage	2.5e-36	100.0
AZP98270.1\|920688_921564_+	hypothetical protein	A0A0P0IJW5	Lactobacillus_phage	1.1e-170	100.0
AZP98271.1\|921566_921761_+	hypothetical protein	A0A0P0IZQ2	Lactobacillus_phage	2.5e-30	100.0
AZP98272.1\|921760_922648_+	recombinase RecT	A0A0P0HRX2	Lactobacillus_phage	8.6e-163	100.0
AZP98273.1\|922656_922902_+	XRE family transcriptional regulator	A0A0P0IV68	Lactobacillus_phage	2.6e-37	100.0
AZP98274.1\|922906_923752_+	DnaD domain protein	A0A0N7IRA7	Lactobacillus_phage	1.0e-133	100.0
AZP98275.1\|923789_924611_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.1e-155	100.0
AZP98276.1\|924607_924907_+	hypothetical protein	A0A0P0IK66	Lactobacillus_phage	2.1e-49	100.0
AZP98277.1\|924869_925154_+	hypothetical protein	A0A0P0IDD7	Lactobacillus_phage	8.8e-45	100.0
AZP98278.1\|925122_925470_+	hypothetical protein	A0A0P0IQU7	Lactobacillus_phage	1.5e-62	100.0
AZP98279.1\|925462_926041_+	HNH endonuclease	A0A0P0I7T6	Lactobacillus_phage	1.1e-105	100.0
AZP98280.1\|926054_926477_+	RusA family crossover junction endodeoxyribonuclease	A0A0P0IXM5	Lactobacillus_phage	5.5e-75	100.0
AZP98281.1\|926481_926745_+	hypothetical protein	A0A0P0IJX1	Lactobacillus_phage	6.1e-40	100.0
AZP98282.1\|926768_927092_+	hypothetical protein	A0A0N7IRA8	Lactobacillus_phage	9.7e-56	100.0
AZP98283.1\|927170_927620_+	sigma-70 family RNA polymerase sigma factor	A0A0P0IZR0	Lactobacillus_phage	1.2e-80	100.0
AZP98284.1\|927844_928225_+	HNH endonuclease	A0A0P0HRY0	Lactobacillus_phage	2.5e-71	100.0
AZQ00292.1\|928294_928669_+	hypothetical protein	A0A1B0YE76	Lactobacillus_phage	3.6e-62	100.0
AZP98285.1\|928671_930402_+\|terminase	terminase large subunit	A0A0P0IJU3	Lactobacillus_phage	0.0e+00	100.0
AZP98286.1\|930420_931656_+\|portal	phage portal protein	A0A0P0IZM3	Lactobacillus_phage	2.6e-234	100.0
AZP98287.1\|931633_932341_+\|protease	Clp protease ClpP	A0A0P0HRU7	Lactobacillus_phage	7.2e-128	100.0
AZP98288.1\|932345_933575_+\|capsid	phage major capsid protein	A0A0P0IV50	Lactobacillus_phage	7.3e-229	100.0
AZP98289.1\|933648_933897_+	hypothetical protein	A0A0P0I3K0	Lactobacillus_phage	9.1e-38	100.0
AZP98290.1\|933910_934237_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B0Y2R7	Lactobacillus_phage	7.0e-54	100.0
AZP98291.1\|934175_934514_+\|head,tail	phage head-tail joining protein	A0A0N7IRA3	Lactobacillus_phage	2.2e-58	100.0
AZP98292.1\|934497_934827_+	hypothetical protein	A0A0P0IDB8	Lactobacillus_phage	3.1e-57	100.0
AZP98293.1\|934816_935200_+	hypothetical protein	A0A0P0IQS9	Lactobacillus_phage	4.5e-68	100.0
AZP98294.1\|935211_935859_+\|tail	phage tail protein	A0A0P0I7R6	Lactobacillus_phage	1.5e-119	100.0
AZP98295.1\|935935_936301_+	hypothetical protein	A0A0P0IXK4	Lactobacillus_phage	4.6e-62	100.0
AZP98296.1\|936562_939535_+	tape measure domain-containing protein	A0A0P0IZN3	Lactobacillus_phage	1.3e-292	100.0
AZP98297.1\|939541_940237_+\|tail	phage tail protein	A0A0P0HRV6	Lactobacillus_phage	8.3e-129	100.0
AZP98298.1\|940233_944640_+	hypothetical protein	A0A0N7IRA4	Lactobacillus_phage	0.0e+00	100.0
AZP98299.1\|944668_945094_+	DUF1617 domain-containing protein	A0A1B0Y2S1	Lactobacillus_phage	8.8e-73	100.0
AZP98300.1\|945096_945366_+	hypothetical protein	A0A0P0I3K6	Lactobacillus_phage	2.4e-39	100.0
AZP98301.1\|945411_945705_+	hypothetical protein	A0A0P0IK41	Lactobacillus_phage	4.0e-48	100.0
AZP98302.1\|945694_946129_+\|holin	phage holin	A0A0P0IDC6	Lactobacillus_phage	7.4e-51	100.0
AZP98303.1\|946128_946317_+	hypothetical protein	A0A0P0IQT6	Lactobacillus_phage	6.7e-25	100.0
AZP98304.1\|946303_947278_+	N-acetylmuramoyl-L-alanine amidase	A0A0P0I7S1	Lactobacillus_phage	9.1e-198	100.0
AZP98305.1\|947799_949311_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
AZP98306.1\|949338_950898_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
AZP98307.1\|950994_951468_+	glutathione peroxidase	NA	NA	NA	NA
AZP98308.1\|951934_953140_+	putative C-S lyase	NA	NA	NA	NA
AZP98309.1\|953156_954155_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.5e-49	38.4
AZP98310.1\|954392_955721_-	phosphohydrolase	NA	NA	NA	NA
AZP98311.1\|955911_956178_+	ACT domain-containing protein	NA	NA	NA	NA
AZP98312.1\|956226_957570_+	PFL family protein	NA	NA	NA	NA
AZP98313.1\|957679_958735_+	competence protein	NA	NA	NA	NA
AZP98314.1\|958924_959560_-	dihydroorotate dehydrogenase	NA	NA	NA	NA
AZP98315.1\|959629_960223_-	CYTH domain-containing protein	NA	NA	NA	NA
AZP98316.1\|960416_961088_+	GTP pyrophosphokinase	NA	NA	NA	NA
AZP98317.1\|961089_961887_+	NAD(+) kinase	NA	NA	NA	NA
AZP98318.1\|961886_962789_+	RluA family pseudouridine synthase	NA	NA	NA	NA
AZP98319.1\|962897_963956_-	FAD:protein FMN transferase	NA	NA	NA	NA
AZP98320.1\|964112_964748_-	copper homeostasis protein CutC	NA	NA	NA	NA
AZP98321.1\|964769_965588_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
AZP98322.1\|965790_966831_-	lactonase family protein	NA	NA	NA	NA
AZP98323.1\|967102_967480_+	PTS sorbitol transporter subunit IIA	NA	NA	NA	NA
AZP98324.1\|967591_967861_-	30S ribosomal protein S14	NA	NA	NA	NA
967808:967826	attR	NA	NA	NA	NA
AZP98325.1\|967988_968978_-	guanosine monophosphate reductase	Q4ZCY7	Staphylococcus_virus	1.4e-137	71.6
AZP98326.1\|969205_970153_-	magnesium transporter CorA family protein	NA	NA	NA	NA
AZP98327.1\|970218_971061_+	methyltransferase domain-containing protein	NA	NA	NA	NA
AZP98328.1\|971104_971317_-	hypothetical protein	NA	NA	NA	NA
AZP98329.1\|971315_971825_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA

DBSCAN-SWA_5

1004400 : 1103344

103

Lactobacillus_phage(77.05%)

portal,integrase,capsid,holin,head,protease,tRNA,tail,terminase

attL 1028051:1028069|attR 1062959:1062977

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP98360.1\|1004400_1004736_+\|holin	phage holin family protein	NA	NA	NA	NA
AZP98361.1\|1004927_1005887_+	HPr kinase/phosphorylase	NA	NA	NA	NA
AZP98362.1\|1005888_1006716_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
AZP98363.1\|1006726_1007782_+	glycerol-3-phosphate dehydrogenase (NAD(P)(+))	NA	NA	NA	NA
AZP98364.1\|1007847_1008801_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	8.9e-81	47.9
AZQ00293.1\|1009384_1011112_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.3e-182	54.9
AZP98365.1\|1011346_1011994_+	DNA-binding response regulator	NA	NA	NA	NA
AZP98366.1\|1011986_1012997_+	sensor histidine kinase	NA	NA	NA	NA
AZP98367.1\|1013767_1016134_+	ABC transporter permease	NA	NA	NA	NA
AZP98368.1\|1016291_1016939_+	hydrolase	NA	NA	NA	NA
AZP98369.1\|1017144_1019160_+	excinuclease ABC subunit B	NA	NA	NA	NA
AZP98370.1\|1019427_1022319_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.9e-307	56.2
AZP98371.1\|1022411_1022612_+	hypothetical protein	NA	NA	NA	NA
AZP98372.1\|1022670_1023210_+	hypothetical protein	NA	NA	NA	NA
AZP98373.1\|1023372_1024260_+	RNase adaptor protein RapZ	A0A0R8VB27	Thermobifida_phage	1.1e-08	31.4
AZP98374.1\|1024256_1025285_+	hypothetical protein	A1IMD5	Streptococcus_phage	2.3e-90	51.2
AZP98375.1\|1025289_1026237_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	9.2e-54	40.7
AZP98376.1\|1026622_1027078_+	MarR family transcriptional regulator	NA	NA	NA	NA
AZP98377.1\|1027194_1027785_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.1e-52	52.3
1028051:1028069	attL	NA	NA	NA	NA
AZP98378.1\|1028189_1029341_-\|integrase	site-specific integrase	Q8W767	Lactobacillus_phage	2.2e-219	100.0
AZP98379.1\|1029451_1030213_-	hypothetical protein	A0A1B0YA83	Lactobacillus_phage	1.2e-144	100.0
AZP98380.1\|1030231_1030462_+	2-hydroxymuconic semialdehyde hydrolase	U5U783	Lactobacillus_phage	7.2e-37	100.0
AZQ00294.1\|1030530_1030626_-	hypothetical protein	NA	NA	NA	NA
AZP98381.1\|1030717_1031497_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	9.1e-116	100.0
AZP98382.1\|1031568_1031973_-	ImmA/IrrE family metallo-endopeptidase	A0A1B0Y2S4	Lactobacillus_phage	2.1e-76	100.0
AZP98383.1\|1031969_1032296_-	XRE family transcriptional regulator	A0A1B0Y3N1	Lactobacillus_phage	3.4e-56	100.0
AZP98384.1\|1032552_1032765_+	helix-turn-helix domain-containing protein	A0A1B0YC38	Lactobacillus_phage	3.7e-32	100.0
AZP98385.1\|1032767_1033541_+	hypothetical protein	A0A1B0YEA7	Lactobacillus_phage	1.3e-143	100.0
AZP98386.1\|1033572_1033896_+	DUF771 domain-containing protein	A0A1B0Y6D5	Lactobacillus_phage	1.2e-58	100.0
AZP98387.1\|1034163_1034475_-	hypothetical protein	A0A1B0YA89	Lactobacillus_phage	8.2e-52	100.0
AZP98388.1\|1034535_1034727_+	hypothetical protein	A0A1B0Y2S8	Lactobacillus_phage	6.4e-31	100.0
AZP98389.1\|1034740_1034980_+	hypothetical protein	A0A1B0Y2S6	Lactobacillus_phage	7.7e-34	100.0
AZP98390.1\|1034984_1035479_+	hypothetical protein	A0A1B0Y2S7	Lactobacillus_phage	9.9e-84	100.0
AZP98391.1\|1035490_1035721_+	hypothetical protein	A0A1B0Y3N2	Lactobacillus_phage	3.0e-35	100.0
AZP98392.1\|1035720_1037088_+	ATP-dependent helicase	A0A1B0YC45	Lactobacillus_phage	1.6e-264	100.0
AZP98393.1\|1037089_1037830_+	NTP-binding protein	A0A1B0YEB5	Lactobacillus_phage	4.1e-134	100.0
AZP98394.1\|1037832_1038342_+	DUF669 domain-containing protein	A0A1B0Y6E2	Lactobacillus_phage	4.1e-93	100.0
AZP98395.1\|1038408_1039206_+	DNA primase	A0A1B0Y4T1	Lactobacillus_phage	1.4e-151	100.0
AZQ00295.1\|1039210_1040446_+	helicase	A0A1B0Y896	Lactobacillus_phage	1.1e-237	100.0
AZP98396.1\|1040720_1041035_+	VRR-NUC domain-containing protein	A0A1B0YA93	Lactobacillus_phage	1.4e-54	100.0
AZP98397.1\|1041041_1041326_+	hypothetical protein	A0A1B0Y2T1	Lactobacillus_phage	6.8e-45	100.0
AZP98398.1\|1041294_1041642_+	hypothetical protein	A0A1B0Y2S9	Lactobacillus_phage	2.2e-58	99.1
AZP98399.1\|1041634_1042222_+	HNH endonuclease	A0A1B0Y2T0	Lactobacillus_phage	9.9e-107	100.0
AZP98400.1\|1042208_1042463_+	hypothetical protein	A0A1B0Y3N3	Lactobacillus_phage	2.3e-44	100.0
AZP98401.1\|1042459_1042864_+	transcriptional regulator	A0A1B0YC57	Lactobacillus_phage	9.3e-72	100.0
AZP98402.1\|1043028_1043409_+	HNH endonuclease	A0A1B0YEC6	Lactobacillus_phage	1.5e-71	100.0
AZQ00296.1\|1043477_1043852_+	hypothetical protein	A0A1B0YE76	Lactobacillus_phage	3.6e-62	100.0
AZP98403.1\|1043854_1045585_+\|terminase	terminase large subunit	A0A1B0Y6B8	Lactobacillus_phage	0.0e+00	100.0
AZP98404.1\|1045603_1046839_+\|portal	phage portal protein	A0A1B0Y4Q9	Lactobacillus_phage	1.2e-234	100.0
AZP98405.1\|1046816_1047524_+\|protease	Clp protease ClpP	A0A1B0Y857	Lactobacillus_phage	1.4e-128	100.0
AZP98406.1\|1047528_1048758_+\|capsid	phage major capsid protein	A0A1B0YA73	Lactobacillus_phage	1.6e-228	99.8
AZP98407.1\|1048831_1049080_+	hypothetical protein	A0A1B0Y2R9	Lactobacillus_phage	7.0e-38	100.0
AZP98408.1\|1049093_1049420_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B0Y2R7	Lactobacillus_phage	7.0e-54	100.0
AZP98409.1\|1049358_1049697_+\|head,tail	phage head-tail joining protein	A0A0N7IRA3	Lactobacillus_phage	2.2e-58	100.0
AZP98410.1\|1049680_1050010_+	hypothetical protein	A0A1B0Y3M9	Lactobacillus_phage	3.1e-57	100.0
AZP98411.1\|1049999_1050383_+	hypothetical protein	A0A1B0YC24	Lactobacillus_phage	2.6e-68	100.0
AZP98412.1\|1050394_1051042_+\|tail	phage tail protein	A0A1B0Y6C3	Lactobacillus_phage	1.2e-118	100.0
AZP98413.1\|1051118_1051484_+	hypothetical protein	A0A1B0Y865	Lactobacillus_phage	4.6e-62	100.0
AZP98414.1\|1051745_1054916_+\|tail	phage tail tape measure protein	A0A1B0YA78	Lactobacillus_phage	0.0e+00	99.9
AZP98415.1\|1054922_1055618_+\|tail	phage tail protein	A0A1B0Y2S2	Lactobacillus_phage	8.3e-129	100.0
AZP98416.1\|1055614_1060018_+	hypothetical protein	A0A1B0Y2S0	Lactobacillus_phage	0.0e+00	100.0
AZP98417.1\|1060046_1060472_+	DUF1617 domain-containing protein	A0A1B0Y2S1	Lactobacillus_phage	8.8e-73	100.0
AZP98418.1\|1060474_1060744_+	hypothetical protein	A0A1B0Y3N0	Lactobacillus_phage	1.3e-40	100.0
AZP98419.1\|1060791_1061178_+	hypothetical protein	A0A1B0YC31	Lactobacillus_phage	5.6e-66	100.0
AZP98420.1\|1061158_1061365_+	hypothetical protein	A0A1B0YE97	Lactobacillus_phage	1.4e-12	100.0
AZP98421.1\|1061361_1061823_+\|holin	phage holin	A0A1B0Y6C9	Lactobacillus_phage	1.2e-70	100.0
AZP98422.1\|1061824_1062877_+	N-acetylmuramoyl-L-alanine amidase	A0A1B0Y4R9	Lactobacillus_phage	2.3e-207	100.0
AZP98423.1\|1063653_1064691_+	central glycolytic genes regulator	NA	NA	NA	NA
1062959:1062977	attR	NA	NA	NA	NA
AZP98424.1\|1064727_1065750_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
AZP98425.1\|1065940_1067131_+	phosphoglycerate kinase	NA	NA	NA	NA
AZP98426.1\|1067205_1067961_+	triose-phosphate isomerase	NA	NA	NA	NA
AZP98427.1\|1068009_1069314_+	enolase	A0A1X9I5Z8	Streptococcus_phage	5.7e-163	67.1
AZP98428.1\|1069643_1070906_+	MFS transporter	A0A1B0RXG2	Streptococcus_phage	3.6e-61	34.9
AZP98429.1\|1070911_1071268_+	hypothetical protein	NA	NA	NA	NA
AZP98430.1\|1071356_1072928_+	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
AZP98431.1\|1073113_1073350_+	preprotein translocase subunit SecG	NA	NA	NA	NA
AZP98432.1\|1073592_1074327_+	esterase	NA	NA	NA	NA
AZP98433.1\|1074328_1076698_+	ribonuclease R	Q0GXV6	Lactococcus_phage	6.6e-93	38.4
AZP98434.1\|1076729_1077203_+	SsrA-binding protein	W5RAM5	Staphylococcus_phage	1.2e-46	60.5
AZP98435.1\|1077599_1078553_+	LacI family transcriptional regulator	NA	NA	NA	NA
AZP98436.1\|1078757_1080434_+	alpha-glucosidase	NA	NA	NA	NA
AZP98437.1\|1080430_1082176_+	alpha-glycosidase	NA	NA	NA	NA
AZP98438.1\|1082305_1084567_+	family 65 glycosyl hydrolase	NA	NA	NA	NA
AZP98439.1\|1084559_1085252_+	beta-phosphoglucomutase	NA	NA	NA	NA
AZQ00297.1\|1085256_1086387_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.4e-21	32.4
AZP98440.1\|1086414_1088040_+	alpha-glucosidase	NA	NA	NA	NA
AZP98441.1\|1088079_1089312_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
AZP98442.1\|1089381_1090740_+	sugar ABC transporter permease	NA	NA	NA	NA
AZP98443.1\|1090745_1091603_+	sugar ABC transporter permease	NA	NA	NA	NA
AZP98444.1\|1091740_1092043_+	hypothetical protein	NA	NA	NA	NA
AZP98445.1\|1092032_1092221_+	transcriptional regulator	NA	NA	NA	NA
AZP98446.1\|1092626_1093874_-	MBL fold hydrolase	NA	NA	NA	NA
AZP98447.1\|1094002_1095316_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AZP98448.1\|1095325_1096147_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
AZP98449.1\|1096162_1097056_-	sugar ABC transporter permease	NA	NA	NA	NA
AZP98450.1\|1097045_1098107_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.1e-18	48.9
AZP98451.1\|1098380_1099058_+	N-acetyltransferase	NA	NA	NA	NA
AZP98452.1\|1099368_1099875_-	hypothetical protein	NA	NA	NA	NA
AZQ00298.1\|1099888_1100014_-	acetyltransferase	NA	NA	NA	NA
AZP98453.1\|1100087_1100981_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AZP98454.1\|1101100_1101787_+	uracil-DNA glycosylase	A0A0S1TKU8	Elephant_endotheliotropic_herpesvirus	2.1e-39	41.7
AZP98455.1\|1101908_1102886_+	phosphate acetyltransferase	NA	NA	NA	NA
AZP98456.1\|1102882_1103344_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA

DBSCAN-SWA_6

1197494 : 1238241

Staphylococcus_phage(22.22%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP98549.1\|1197494_1198325_-\|transposase	transposase	NA	NA	NA	NA
AZP98550.1\|1198369_1199098_-\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	7.6e-32	40.1
AZP98551.1\|1199342_1200209_+\|protease	Zn-dependent protease	NA	NA	NA	NA
AZP98552.1\|1200205_1200640_+\|protease	Zn-dependent protease	NA	NA	NA	NA
AZP98553.1\|1200799_1201675_-	dTDP-glucose 4,6-dehydratase	NA	NA	NA	NA
AZP98554.1\|1201727_1202726_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.8e-55	39.8
AZP98555.1\|1202784_1203666_+	DUF3324 domain-containing protein	NA	NA	NA	NA
AZP98556.1\|1203640_1203961_+	cell surface complex protein, CscD family	NA	NA	NA	NA
AZP98557.1\|1203974_1205588_+	protein export cytoplasm protein SecA2 ATPase RNA helicase	NA	NA	NA	NA
AZP98558.1\|1205785_1207234_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
AZP98559.1\|1207314_1209168_-	PTS beta-glucoside transporter subunit EIIBCA	NA	NA	NA	NA
AZP98560.1\|1209254_1210085_-	PRD domain-containing protein	NA	NA	NA	NA
AZP98561.1\|1210097_1210244_-	hypothetical protein	NA	NA	NA	NA
AZP98562.1\|1210582_1210732_+	hypothetical protein	NA	NA	NA	NA
AZP98563.1\|1210750_1213414_-	hypothetical protein	NA	NA	NA	NA
AZP98564.1\|1213724_1215464_+	hypothetical protein	NA	NA	NA	NA
AZP98565.1\|1215815_1216745_-	glycosyltransferase	V5USA4	Oenococcus_phage	3.9e-73	47.7
AZP98566.1\|1216831_1217470_-	hypothetical protein	NA	NA	NA	NA
AZP98567.1\|1217597_1218563_+	hypothetical protein	NA	NA	NA	NA
AZP98568.1\|1218710_1218839_+	transcription elongation factor GreAB	NA	NA	NA	NA
AZP98569.1\|1219522_1219723_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.2e-19	66.2
AZP98570.1\|1219964_1220447_+	N-acetyltransferase	NA	NA	NA	NA
AZQ00302.1\|1220452_1221088_+	N-acetylmuramidase	A0A0A7RUS8	Clostridium_phage	8.4e-27	47.7
AZQ00303.1\|1221212_1221857_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
AZP98571.1\|1221863_1223192_+	purine permease	Q9KX94	Enterobacteria_phage	1.6e-35	31.7
AZP98572.1\|1223212_1224322_+	phosphoribosylaminoimidazole carboxylase	NA	NA	NA	NA
AZP98573.1\|1224391_1225687_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.4e-14	28.5
AZP98574.1\|1225808_1226378_-	branched-chain amino acid ABC transporter ATP-binding protein	NA	NA	NA	NA
AZP98575.1\|1226387_1227134_-	hypothetical protein	NA	NA	NA	NA
AZP98576.1\|1227219_1229475_-	LTA synthase family protein	W6LM83	Streptococcus_phage	4.7e-157	44.6
AZP98577.1\|1229940_1230546_+	VanZ family protein	NA	NA	NA	NA
AZP98578.1\|1230717_1231575_+	glucose transporter GlcU	NA	NA	NA	NA
AZP98579.1\|1231788_1233129_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
AZP98580.1\|1233487_1234267_-	DUF1829 domain-containing protein	NA	NA	NA	NA
AZP98581.1\|1234368_1234656_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
AZP98582.1\|1234837_1235368_-	hypothetical protein	NA	NA	NA	NA
AZP98583.1\|1235448_1236300_-	DNA/RNA endonuclease	NA	NA	NA	NA
AZP98584.1\|1236296_1237046_-	DNA-entry nuclease	NA	NA	NA	NA
AZP98585.1\|1237242_1238241_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.8e-55	39.8

DBSCAN-SWA_7

1997457 : 2022369

unidentified_phage(40.0%)

transposase,integrase

attL 2001591:2001604|attR 2022376:2022389

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP99302.1\|1997457_1998387_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9
AZP99303.1\|1998511_1999279_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
AZP99304.1\|1999591_2001187_+	surface protein, LPXTG-anchored	NA	NA	NA	NA
2001591:2001604	attL	NA	NA	NA	NA
AZP99305.1\|2001887_2002217_+	XRE family transcriptional regulator	NA	NA	NA	NA
AZP99306.1\|2002593_2003238_+	DUF4767 domain-containing protein	NA	NA	NA	NA
AZP99307.1\|2004787_2005432_-	hypothetical protein	NA	NA	NA	NA
AZP99308.1\|2005412_2005703_-	hypothetical protein	NA	NA	NA	NA
AZP99309.1\|2006132_2006919_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP99310.1\|2007617_2008139_-	hypothetical protein	NA	NA	NA	NA
AZP99311.1\|2008311_2009428_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.0e-27	32.6
AZP99312.1\|2010687_2011596_+	magnesium transporter CorA family protein	NA	NA	NA	NA
AZP99313.1\|2011879_2012809_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9
AZP99314.1\|2012835_2012916_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
AZP99315.1\|2012922_2013819_-	prolyl aminopeptidase	NA	NA	NA	NA
AZP99316.1\|2013822_2014680_-	peptidase	NA	NA	NA	NA
AZP99317.1\|2014679_2015765_-	M42 family peptidase	NA	NA	NA	NA
AZP99318.1\|2015793_2017413_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
AZP99319.1\|2017684_2018368_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
AZP99320.1\|2018427_2018628_+	restriction endonuclease subunit S	NA	NA	NA	NA
AZP99321.1\|2018653_2018857_-	hypothetical protein	NA	NA	NA	NA
AZP99322.1\|2018773_2018962_+	hypothetical protein	NA	NA	NA	NA
AZQ00323.1\|2019451_2019655_+	peptide ABC transporter permease	NA	NA	NA	NA
AZP99323.1\|2019897_2020296_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AZP99324.1\|2020316_2020568_+	hypothetical protein	NA	NA	NA	NA
AZP99325.1\|2020923_2021172_+	DUF3173 domain-containing protein	NA	NA	NA	NA
AZP99326.1\|2021175_2022369_+\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	1.6e-39	32.2
2022376:2022389	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2419759 : 2465446

Streptococcus_phage(40.0%)

portal,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP99682.1\|2419759_2421814_+\|portal	portal protein	M1IAJ4	Acanthocystis_turfacea_Chlorella_virus	1.2e-63	33.3
AZP99683.1\|2421970_2424601_-	pyruvate, phosphate dikinase	H8YJB7	Vibrio_phage	8.4e-89	40.2
AZP99684.1\|2424762_2425386_-	CBS domain-containing protein	NA	NA	NA	NA
AZP99685.1\|2425885_2426557_-	phosphoglycerate mutase	NA	NA	NA	NA
AZP99686.1\|2427066_2428188_+	bacitracin ABC transporter permease	NA	NA	NA	NA
AZP99687.1\|2428201_2428486_+	chromosome partitioning protein ParB	NA	NA	NA	NA
AZP99688.1\|2428676_2429792_-	lactate oxidase	NA	NA	NA	NA
AZP99689.1\|2429979_2430186_-	CsbD family protein	NA	NA	NA	NA
AZP99690.1\|2430335_2431526_-	phosphopentomutase	NA	NA	NA	NA
AZP99691.1\|2431545_2432778_-	MFS transporter	NA	NA	NA	NA
AZP99692.1\|2432822_2433566_-	uridine phosphorylase	NA	NA	NA	NA
AZP99693.1\|2433562_2434777_-	MFS transporter	NA	NA	NA	NA
AZP99694.1\|2434970_2436155_+	PucR family transcriptional regulator	NA	NA	NA	NA
AZP99695.1\|2436237_2436495_-	hypothetical protein	NA	NA	NA	NA
AZP99696.1\|2436565_2436772_-	hypothetical protein	NA	NA	NA	NA
AZP99697.1\|2436996_2437248_-	hypothetical protein	NA	NA	NA	NA
AZP99698.1\|2437374_2437551_+	hypothetical protein	NA	NA	NA	NA
AZQ00336.1\|2437575_2438808_+	MFS transporter	NA	NA	NA	NA
AZP99699.1\|2438886_2440143_-	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	7.3e-99	56.8
AZP99700.1\|2440231_2441065_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	9.6e-47	42.4
AZP99701.1\|2441381_2441576_-	hypothetical protein	NA	NA	NA	NA
AZP99702.1\|2441829_2442366_-	hypothetical protein	NA	NA	NA	NA
AZP99703.1\|2442555_2443779_-	hypothetical protein	NA	NA	NA	NA
AZP99704.1\|2444368_2445196_-	class C sortase	NA	NA	NA	NA
AZP99705.1\|2445202_2446762_-	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
AZP99706.1\|2446758_2448081_-	pilus assembly protein	NA	NA	NA	NA
AZP99707.1\|2448082_2451088_-	hypothetical protein	NA	NA	NA	NA
AZP99708.1\|2451365_2451923_-	hypothetical protein	NA	NA	NA	NA
AZP99709.1\|2452017_2453214_-	DUF2075 domain-containing protein	NA	NA	NA	NA
AZP99710.1\|2453422_2454478_+	DUF2974 domain-containing protein	NA	NA	NA	NA
AZP99711.1\|2454443_2454662_+	hypothetical protein	NA	NA	NA	NA
AZP99712.1\|2454748_2455378_+	XRE family transcriptional regulator	A0A0S2MVM8	Bacillus_phage	1.2e-06	37.5
AZP99713.1\|2455513_2455843_+	PadR family transcriptional regulator	NA	NA	NA	NA
AZP99714.1\|2455839_2456628_+	hypothetical protein	NA	NA	NA	NA
AZP99715.1\|2456680_2457469_+	hypothetical protein	NA	NA	NA	NA
AZP99716.1\|2457513_2457792_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AZP99717.1\|2457815_2458100_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AZP99718.1\|2458293_2458590_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AZP99719.1\|2458691_2460047_-	hypothetical protein	NA	NA	NA	NA
AZP99720.1\|2460352_2460646_-	hypothetical protein	NA	NA	NA	NA
AZP99721.1\|2460736_2461087_-	hypothetical protein	NA	NA	NA	NA
AZP99722.1\|2461260_2462640_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
AZP99723.1\|2465308_2465446_-\|bacteriocin	bacteriocin prepeptide or inducing factor for bacteriocin synthesis	NA	NA	NA	NA

DBSCAN-SWA_9

2469361 : 2498787

Indivirus(25.0%)

transposase,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP99728.1\|2469361_2469544_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
AZP99729.1\|2469573_2469747_-\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
AZP99730.1\|2470068_2470293_+	hypothetical protein	NA	NA	NA	NA
AZP99731.1\|2470607_2470772_-	cytosolic protein	NA	NA	NA	NA
AZP99732.1\|2471009_2471855_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AZP99733.1\|2472372_2472705_-	hypothetical protein	NA	NA	NA	NA
AZP99734.1\|2472960_2473629_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AZP99735.1\|2473609_2473801_-	hypothetical protein	NA	NA	NA	NA
AZP99736.1\|2474119_2474455_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AZP99737.1\|2474573_2475170_-	sugar O-acetyltransferase	NA	NA	NA	NA
AZP99738.1\|2475262_2475451_+	hypothetical protein	NA	NA	NA	NA
AZP99739.1\|2475440_2475749_-	hypothetical protein	NA	NA	NA	NA
AZP99740.1\|2475884_2476100_-\|bacteriocin	class IIb bacteriocin	NA	NA	NA	NA
AZP99741.1\|2476096_2476330_-\|bacteriocin	class IIb bacteriocin	NA	NA	NA	NA
AZP99742.1\|2476601_2477555_-	aldo/keto reductase	A0A1V0SDE7	Indivirus	4.8e-10	24.6
AZP99743.1\|2477759_2478494_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AZP99744.1\|2478519_2479683_+	NADH-dependent flavin oxidoreductase	NA	NA	NA	NA
AZP99745.1\|2479824_2479989_+	acetyltransferase	NA	NA	NA	NA
AZP99746.1\|2480193_2481570_-	class II fumarate hydratase	NA	NA	NA	NA
AZP99747.1\|2481702_2482461_-	hypothetical protein	NA	NA	NA	NA
AZP99748.1\|2482625_2482769_-	hypothetical protein	NA	NA	NA	NA
AZP99749.1\|2482752_2484360_-	divalent metal cation transporter	NA	NA	NA	NA
AZP99750.1\|2484747_2487465_+	cation-transporting ATPase	M1HJQ2	Paramecium_bursaria_Chlorella_virus	1.2e-61	29.1
AZP99751.1\|2487764_2488130_+	hypothetical protein	NA	NA	NA	NA
AZP99752.1\|2488283_2489657_-	MFS transporter	NA	NA	NA	NA
AZP99753.1\|2489696_2491226_-	copper oxidase	NA	NA	NA	NA
AZP99754.1\|2491227_2491407_+	hypothetical protein	NA	NA	NA	NA
AZP99755.1\|2491471_2491663_+	hypothetical protein	NA	NA	NA	NA
AZP99756.1\|2491791_2492430_+	cation transporter	NA	NA	NA	NA
AZP99757.1\|2492450_2492783_+	ArsR family transcriptional regulator	NA	NA	NA	NA
AZP99758.1\|2492903_2493845_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
AZP99759.1\|2493841_2494738_-	metal ABC transporter permease	NA	NA	NA	NA
AZP99760.1\|2494734_2495478_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-12	25.9
AZP99761.1\|2495753_2497220_-	aldehyde dehydrogenase	NA	NA	NA	NA
AZP99762.1\|2497420_2497690_-	30S ribosomal protein S14	NA	NA	NA	NA
AZP99763.1\|2497720_2497831_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
AZP99764.1\|2497857_2498787_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9

DBSCAN-SWA_10

2975705 : 2987074

uncultured_Caudovirales_phage(37.5%)

portal,capsid,head,tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZQ00218.1\|2975705_2976344_-	transcriptional regulator	L0P7E1	Lactobacillus_phage	2.4e-05	27.6
AZQ00219.1\|2976511_2976787_+	DNA-binding protein	NA	NA	NA	NA
AZQ00220.1\|2976854_2977076_+	hypothetical protein	NA	NA	NA	NA
AZQ00221.1\|2977186_2977378_+	hypothetical protein	NA	NA	NA	NA
AZQ00222.1\|2977424_2977715_+	hypothetical protein	NA	NA	NA	NA
AZQ00223.1\|2977711_2977900_+	hypothetical protein	NA	NA	NA	NA
AZQ00224.1\|2977883_2978696_+	DNA replication protein	Q854C1	Mycobacterium_phage	6.7e-13	34.2
AZQ00225.1\|2978708_2980295_+	DNA primase	A0A1B1P7L5	Bacillus_phage	4.0e-25	27.9
AZQ00226.1\|2980620_2980956_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AZQ00227.1\|2980960_2981146_+	hypothetical protein	NA	NA	NA	NA
AZQ00228.1\|2981142_2981565_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	1.2e-21	45.4
AZQ00229.1\|2981681_2982152_+\|terminase	phage terminase small subunit P27 family	M1PKP2	Streptococcus_phage	4.6e-06	26.5
AZQ00230.1\|2982148_2983852_+\|terminase	terminase	A0A2H4JBN3	uncultured_Caudovirales_phage	2.3e-116	42.1
AZQ00231.1\|2983817_2983997_+	hypothetical protein	NA	NA	NA	NA
AZQ00232.1\|2984001_2985183_+\|portal	phage portal protein	A0A2H4JB06	uncultured_Caudovirales_phage	2.8e-60	35.5
AZQ00233.1\|2985169_2986726_+\|capsid	phage major capsid protein	A0A2H4J9X8	uncultured_Caudovirales_phage	4.6e-34	32.0
AZQ00234.1\|2986780_2987074_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP025498

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 65277

Staphylococcus_phage(43.75%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP97341.1\|9535_9787_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	1.5e-35	92.8
AZP97412.1\|10969_11167_+	XRE family transcriptional regulator	NA	NA	NA	NA
AZP97342.1\|11366_11834_-	hypothetical protein	NA	NA	NA	NA
AZP97343.1\|12107_12758_+	recombinase family protein	M9Q1K0	Clostridium_phage	1.5e-18	37.6
AZP97344.1\|12763_13048_+	cytosolic protein	NA	NA	NA	NA
AZP97345.1\|13109_13896_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP97346.1\|13883_14207_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
AZP97347.1\|14562_15441_+	transcription antiterminator lact	NA	NA	NA	NA
AZP97348.1\|15561_17295_+	PTS lactose transporter subunit IIB	NA	NA	NA	NA
AZP97349.1\|17321_18746_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
AZP97350.1\|18794_19130_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
AZP97351.1\|20609_21167_-	serine acetyltransferase	NA	NA	NA	NA
AZP97352.1\|21132_22317_-	cystathionine gamma-synthase	NA	NA	NA	NA
AZP97353.1\|22338_23250_-	cysteine synthase family protein	A0A1W6JIM2	Lactococcus_phage	2.8e-60	41.7
AZP97354.1\|23993_27161_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.1e-21	22.6
AZP97355.1\|27174_28791_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.3e-127	50.3
AZP97356.1\|28787_29414_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.4e-10	30.0
AZP97357.1\|29481_30268_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP97358.1\|30276_30636_-	hypothetical protein	NA	NA	NA	NA
AZP97359.1\|30641_31535_-	endonuclease	NA	NA	NA	NA
AZP97360.1\|31624_32308_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
AZP97361.1\|32644_33475_-	TIGR00268 family protein	NA	NA	NA	NA
AZP97362.1\|33499_34216_-	aquaporin family protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	4.1e-22	33.6
AZP97363.1\|34220_35483_-	TIGR00299 family protein	NA	NA	NA	NA
AZP97364.1\|35513_36254_-	1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate carboxylase	A0A288TYA6	Enterococcus_phage	4.7e-21	47.2
AZP97365.1\|36328_37012_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
AZP97366.1\|37149_37936_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
AZP97367.1\|37944_38304_-	hypothetical protein	NA	NA	NA	NA
AZP97368.1\|38309_39203_-	endonuclease	NA	NA	NA	NA
AZP97369.1\|39292_39976_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
AZP97370.1\|40312_41143_-	TIGR00268 family protein	NA	NA	NA	NA
AZP97371.1\|41167_41884_-	aquaporin family protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	4.1e-22	33.6
AZP97372.1\|41888_43151_-	TIGR00299 family protein	NA	NA	NA	NA
AZP97373.1\|43181_43922_-	1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate carboxylase	A0A288TYA6	Enterococcus_phage	4.7e-21	47.2
AZP97374.1\|43996_44680_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
AZP97375.1\|44768_44957_+	hypothetical protein	NA	NA	NA	NA
AZP97376.1\|44969_45128_+	hypothetical protein	NA	NA	NA	NA
AZP97377.1\|45216_45615_+	hypothetical protein	NA	NA	NA	NA
AZP97378.1\|45626_45893_+	hypothetical protein	NA	NA	NA	NA
AZP97379.1\|45916_47440_+	DUF5011 domain-containing protein	NA	NA	NA	NA
AZP97380.1\|47458_47935_+	PcfB family protein	NA	NA	NA	NA
AZP97381.1\|47934_49830_+	type IV secretion system protein VirD4	NA	NA	NA	NA
AZP97382.1\|49847_50054_+	hypothetical protein	NA	NA	NA	NA
AZP97383.1\|50073_50907_+	hypothetical protein	NA	NA	NA	NA
AZP97384.1\|50924_51296_+	PrgI family protein	NA	NA	NA	NA
AZP97385.1\|51243_53700_+	conjugal transfer protein	NA	NA	NA	NA
AZP97386.1\|53689_56167_+	CHAP domain-containing protein	A0A1X9SGZ2	Bradyrhizobium_phage	9.3e-13	36.8
AZP97387.1\|56180_56705_+	hypothetical protein	NA	NA	NA	NA
AZP97388.1\|56722_56953_+	hypothetical protein	NA	NA	NA	NA
AZP97389.1\|56988_58134_+	hypothetical protein	NA	NA	NA	NA
AZP97390.1\|58151_59126_+	DNA primase	NA	NA	NA	NA
AZP97391.1\|59213_59489_+	hypothetical protein	NA	NA	NA	NA
AZP97392.1\|59485_59734_+	hypothetical protein	NA	NA	NA	NA
AZP97413.1\|59925_60132_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AZP97393.1\|60103_62311_+	ATPase	NA	NA	NA	NA
AZP97394.1\|62355_63747_+	DUF3991 domain-containing protein	NA	NA	NA	NA
AZP97395.1\|64114_64234_+\|holin	putative holin-like toxin	NA	NA	NA	NA
AZP97396.1\|64593_65277_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8

DBSCAN-SWA_2

70152 : 73042

Enterococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZP97405.1\|70152_70989_+	ParA family protein	F0PIG8	Enterococcus_phage	1.1e-37	36.7
AZP97406.1\|70981_71371_+	hypothetical protein	NA	NA	NA	NA
AZP97407.1\|71415_71757_-	hypothetical protein	NA	NA	NA	NA
AZP97408.1\|71749_73042_-	DNA polymerase	O64031	Bacillus_phage	1.3e-79	39.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025499

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP025498

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection