CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
AP018516	Acetobacter orientalis plasmid pAOF1 FAN1 DNA, complete genome	0 crisprs	NA	0	0	2	0
AP018515	Acetobacter orientalis FAN1 DNA, complete genome	2 crisprs	DinG,csa3,DEDDh,cas3	0	11	7	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

62272 : 78836

Paenibacillus_phage(25.0%)

integrase,transposase

attL 62169:62183|attR 81584:81598

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
62169:62183	attL	NA	NA	NA	NA
BBC81770.1\|62272_62875_+\|transposase	DDE transposase	NA	NA	NA	NA
BBC81771.1\|62900_63248_+\|transposase	IS5 family transposase	NA	NA	NA	NA
BBC81772.1\|63268_63658_+\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	8.8e-11	38.0
BBC81773.1\|63679_63796_-	hypothetical protein APA386B_1668	NA	NA	NA	NA
BBC81774.1\|63911_64550_+\|integrase	integrase	A0A2H4J6I5	uncultured_Caudovirales_phage	4.2e-10	32.5
BBC81775.1\|64623_64896_+	prevent-host-death protein	NA	NA	NA	NA
BBC81776.1\|64892_65276_+	twitching motility protein PilT	NA	NA	NA	NA
BBC81777.1\|65409_66270_-	oxidoreductase	NA	NA	NA	NA
BBC81778.1\|66266_67268_-	lysophospholipase	NA	NA	NA	NA
BBC81779.1\|67277_67583_-	ethyl tert-butyl ether degradation protein EthD	NA	NA	NA	NA
BBC81780.1\|67579_68293_-	dehydrogenase with different specificities	NA	NA	NA	NA
BBC81781.1\|68362_68965_+	putative hth-type transcriptional regulator yjgj	NA	NA	NA	NA
BBC81782.1\|69200_69917_-	short-chain dehydrogenase	NA	NA	NA	NA
BBC81783.1\|69958_70846_-	oxidoreductase	NA	NA	NA	NA
BBC81784.1\|70921_71530_+	TetR family transcriptional regulator	NA	NA	NA	NA
BBC81785.1\|71554_72649_+	alkene reductase	NA	NA	NA	NA
BBC81786.1\|72737_72860_-	hypothetical protein	NA	NA	NA	NA
BBC81787.1\|72894_73464_+	glyoxalase	NA	NA	NA	NA
BBC81788.1\|73699_74986_+	MFS transporter	NA	NA	NA	NA
BBC81789.1\|74982_76236_+	arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	2.2e-23	25.1
BBC81790.1\|76717_77908_-\|transposase	IS91 family transposase	NA	NA	NA	NA
BBC81791.1\|77927_78836_-\|integrase	putative integrase/recombinase y4qK	A0A1P8DJJ6	Virus_Rctr41k	5.2e-22	27.4
81584:81598	attR	NA	NA	NA	NA

DBSCAN-SWA_2

91462 : 121335

Burkholderia_virus(20.0%)

protease,transposase,integrase

attL 102717:102734|attR 121350:121367

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBC81810.1\|91462_91765_-\|transposase	DDE transposase	A0A0N9SJT9	Paenibacillus_phage	9.5e-13	40.2
BBC81811.1\|91857_92241_-\|transposase	transposase	NA	NA	NA	NA
BBC81812.1\|92463_93045_+\|protease	protease	NA	NA	NA	NA
BBC81813.1\|93071_93395_+	aryl-sulfate sulfotransferase	NA	NA	NA	NA
BBC81814.1\|93578_94916_+	diguanylate cyclase	NA	NA	NA	NA
BBC81815.1\|95239_98695_-	outer membrane autotransporter barrel domain protein	NA	NA	NA	NA
BBC81816.1\|98867_98984_-\|transposase	transposase	NA	NA	NA	NA
BBC81817.1\|98947_99226_-	insertion element IS476 uncharacterized 39.2 kDa protein-like	NA	NA	NA	NA
BBC81818.1\|99387_99546_+	arac-type DNA-binding domain-containing protein	NA	NA	NA	NA
BBC81819.1\|99565_100048_-	DUF2938 domain-containing protein	NA	NA	NA	NA
BBC81820.1\|100220_100604_+	transcriptional regulator BadM/Rrf2	NA	NA	NA	NA
BBC81821.1\|100678_101707_-	transcriptional regulator NmrA	NA	NA	NA	NA
BBC81822.1\|101755_101878_+\|transposase	transposase	NA	NA	NA	NA
BBC81823.1\|101874_101997_+	mobile element protein	NA	NA	NA	NA
BBC81824.1\|102147_102702_+\|transposase	transposase	S5WIU1	Leptospira_phage	1.3e-36	41.3
102717:102734	attL	NA	NA	NA	NA
BBC81825.1\|102742_102955_+\|transposase	transposase	A4JX31	Burkholderia_virus	4.3e-12	48.6
BBC81826.1\|103154_104957_-	GGDEF-domain containing protein	NA	NA	NA	NA
BBC81827.1\|104949_106506_-	globin-coupled sensor protein	A0A2H4J162	uncultured_Caudovirales_phage	3.0e-09	54.3
BBC81828.1\|106740_107025_+\|transposase	transposase	NA	NA	NA	NA
BBC81829.1\|107060_107201_-\|integrase	integrase	NA	NA	NA	NA
BBC81830.1\|107219_107660_+\|transposase	transposase	A0A0P0I4A4	Acinetobacter_phage	1.7e-23	43.5
BBC81831.1\|107619_108828_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	4.2e-35	32.6
BBC81832.1\|108982_109342_+\|transposase	transposase	A4JX31	Burkholderia_virus	2.4e-15	45.7
BBC81833.1\|109507_110779_+	polymerase	NA	NA	NA	NA
BBC81834.1\|110775_111162_-	hypothetical protein	NA	NA	NA	NA
BBC81835.1\|111191_111752_-	chemotaxis protein CheD	NA	NA	NA	NA
BBC81836.1\|111748_112138_-	response regulator	Q8QKV7	Ectocarpus_siliculosus_virus	3.2e-05	32.1
BBC81837.1\|112229_113270_-	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
BBC81838.1\|113273_114116_-	chemotaxis protein	NA	NA	NA	NA
BBC81839.1\|114115_114571_-	chemotaxis protein CheW	NA	NA	NA	NA
BBC81840.1\|114616_116887_-	chemotaxis protein CheA	NA	NA	NA	NA
BBC81841.1\|116902_117286_-	Fis family transcriptional regulator	Q56AR1	Bacillus_thuringiensis_phage	4.1e-13	35.8
BBC81842.1\|117294_117561_-	cheX protein	NA	NA	NA	NA
BBC81843.1\|117630_119145_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.8e-06	33.5
BBC81844.1\|119169_119298_+	putative transcriptional regulator	NA	NA	NA	NA
BBC81845.1\|119577_120657_+\|transposase	IS5 family transposase	NA	NA	NA	NA
BBC81846.1\|120876_121335_+\|integrase	integrase, partial	NA	NA	NA	NA
121350:121367	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. AP018515

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CRISPR-Cas detection and classification

Crispr_ID: AP018515_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018515_1

2607936-2608444

Orphan

I-F

Consensus_repeat	Method
CTTCACTGCCGCACAGGCAGCTCAGAAA	PILER-CR
CTTCACTGCCGCACAGGCAGCTCAGAAA	CRISPRCasFinder
CTTCACTGCCGCACAGGCAGCTCAGAAA	CRT

8 spacers

The CRISPR arrays of AP018515_1

>merge|AP018515|1|2607936-2608444|PILER-CR,CRISPRCasFinder,CRT
CTTCACTGCCGCACAGGCAGCTCAGAAATGTCCGTAATCAACACGGCGCAAGGCACCCTGCTTCACTGCCGCACAGGCAGCTCAGAAAGGACACGATTGCACCCGCAGGATATCCGCCGACTTCACTGCCGCACAGGCAGCTCAGAAATAGACCGCGCGTAAAGTTGGTCAGCGGGTTGTCTTCACTGCCGCACAGGCAGCTCAGAAAATAAGGCCAAGCGCACCTTCGCCCATGCCGATCTTCACTGCCGCACAGGCAGCTCAGCAAGGCGCAACGGGCGCAACATGGCAGAGCCTGTTCTTCACTGCCGCACAGGCAGCTCAGAAAACCCAGCGCACCAAGGGCCGCACTGTCGATGTCTTCACTGCCGCACAGGCAGCTCAGAAAAGAGGCAGCGCTGGCACCGATCAGCGTGCCAAACTTCACTGCCGCACAGGCAGCTCAGAAACAAAACTCCCGCGCCACAGGGACTTTGCGGGCTTTCACTGCCGCACAGGCAGTTTATATG

>AP018515|1|1|2607936-2608384|PILER-CR
CTTCACTGCCGCACAGGCAGCTCAGAAA	TGTCCGTAATCAACACGGCGCAAGGCACCCTG
CTTCACTGCCGCACAGGCAGCTCAGAAA	GGACACGATTGCACCCGCAGGATATCCGCCGA
CTTCACTGCCGCACAGGCAGCTCAGAAA	TAGACCGCGCGTAAAGTTGGTCAGCGGGTTGT
CTTCACTGCCGCACAGGCAGCTCAGAAA	ATAAGGCCAAGCGCACCTTCGCCCATGCCGAT
CTTCACTGCCGCACAGGCAGCTCAGCAA	GGCGCAACGGGCGCAACATGGCAGAGCCTGTTCTT
CACTGCCGCACAGGCAGCTCAGAAAACC	CAGCGCACCAAGGGCCGCACTGTCGATGTCTT
CACTGCCGCACAGGCAGCTCAGAAAAGA	GGCAGCGCTGGCACCGATCAGCGTGCCAAACTT
CACTGCCGCACAGGCAGCTCAGAAA

>AP018515|1|1|2607936-2608444|CRISPRCasFinder
CTTCACTGCCGCACAGGCAGCTCAGAAA	TGTCCGTAATCAACACGGCGCAAGGCACCCTG
CTTCACTGCCGCACAGGCAGCTCAGAAA	GGACACGATTGCACCCGCAGGATATCCGCCGA
CTTCACTGCCGCACAGGCAGCTCAGAAA	TAGACCGCGCGTAAAGTTGGTCAGCGGGTTGT
CTTCACTGCCGCACAGGCAGCTCAGAAA	ATAAGGCCAAGCGCACCTTCGCCCATGCCGAT
CTTCACTGCCGCACAGGCAGCTCAGCAA	GGCGCAACGGGCGCAACATGGCAGAGCCTGTT
CTTCACTGCCGCACAGGCAGCTCAGAAA	ACCCAGCGCACCAAGGGCCGCACTGTCGATGT
CTTCACTGCCGCACAGGCAGCTCAGAAA	AGAGGCAGCGCTGGCACCGATCAGCGTGCCAAA
CTTCACTGCCGCACAGGCAGCTCAGAAA	CAAAACTCCCGCGCCACAGGGACTTTGCGGGC
TTTCACTGCCGCACAGGCAGTTTATATG

>AP018515|1|1|2607936-2608444|CRT
CTTCACTGCCGCACAGGCAGCTCAGAAA	TGTCCGTAATCAACACGGCGCAAGGCACCCTG
CTTCACTGCCGCACAGGCAGCTCAGAAA	GGACACGATTGCACCCGCAGGATATCCGCCGA
CTTCACTGCCGCACAGGCAGCTCAGAAA	TAGACCGCGCGTAAAGTTGGTCAGCGGGTTGT
CTTCACTGCCGCACAGGCAGCTCAGAAA	ATAAGGCCAAGCGCACCTTCGCCCATGCCGAT
CTTCACTGCCGCACAGGCAGCTCAGCAA	GGCGCAACGGGCGCAACATGGCAGAGCCTGTT
CTTCACTGCCGCACAGGCAGCTCAGAAA	ACCCAGCGCACCAAGGGCCGCACTGTCGATGT
CTTCACTGCCGCACAGGCAGCTCAGAAA	AGAGGCAGCGCTGGCACCGATCAGCGTGCCAAA
CTTCACTGCCGCACAGGCAGCTCAGAAA	CAAAACTCCCGCGCCACAGGGACTTTGCGGGC
TTTCACTGCCGCACAGGCAGTTTATATG

Protein	Signature genes	Signature genes Name	Protein_function
AP018515.1\|BBC81216.1\|2602034_2603294_-\|D-amino-acid-dehydrogenase-small-subunit	unknown	unknown	gnl\|CDD\|234819
AP018515.1\|BBC81224.1\|2609065_2609194_+\|hypothetical-protein-Abor_026_002	unknown	unknown	unknown
AP018515.1\|BBC81227.1\|2610702_2611557_-\|septum-formation-inhibitor-Maf	unknown	unknown	gnl\|CDD\|376812
AP018515.1\|BBC81214.1\|2599512_2601336_+\|GTP-binding-protein-TypA	unknown	unknown	gnl\|CDD\|224138
AP018515.1\|BBC81230.1\|2613685_2613832_-\|hypothetical-protein	unknown	unknown	unknown
AP018515.1\|BBC81225.1\|2609433_2609592_-\|DNA-gyrase-inhibitor-YacG	unknown	unknown	gnl\|CDD\|234943
AP018515.1\|BBC81231.1\|2613819_2616642_-\|ribonuclease-E	unknown	unknown	gnl\|CDD\|224447
AP018515.1\|BBC81217.1\|2603383_2603596_+\|alcohol-dehydrogenase-2	unknown	unknown	unknown
AP018515.1\|BBC81215.1\|2601619_2601928_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236851
AP018515.1\|BBC81232.1\|2617179_2618118_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
AP018515.1\|BBC81228.1\|2611629_2612943_-\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|234853
AP018515.1\|BBC81213.1\|2598878_2599499_-\|Fe2+-transport-protein-A-FeoA	unknown	unknown	gnl\|CDD\|224830
AP018515.1\|BBC81221.1\|2606176_2607787_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|181969
AP018515.1\|BBC81218.1\|2603649_2604711_-\|ferredoxin--NADP(+)-reductase	unknown	unknown	gnl\|CDD\|223566
AP018515.1\|BBC81229.1\|2612957_2613689_-\|ATP-phosphoribosyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234971
AP018515.1\|BBC81212.1\|2597016_2598882_-\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
AP018515.1\|BBC81226.1\|2609611_2610706_-\|ribonuclease,-partial	unknown	unknown	gnl\|CDD\|273254
AP018515.1\|BBC81223.1\|2608679_2608979_+\|integral-membrane-protein,-YggT-family	unknown	unknown	gnl\|CDD\|376765
AP018515.1\|BBC81219.1\|2604667_2604817_+\|asparagine-synthetase-domain-containing-protein-1	unknown	unknown	unknown
AP018515.1\|BBC81220.1\|2604821_2606042_-\|isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|236226

Protein	Function_ID	Function_description	E-value
AP018515.1\|BBC81216.1\|2602034_2603294_-\|D-amino-acid-dehydrogenase-small-subunit	gnl\|CDD\|234819	PRK00711, PRK00711, D-amino acid dehydrogenase.	0
AP018515.1\|BBC81232.1\|2617179_2618118_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	3.14118e-54
AP018515.1\|BBC81227.1\|2610702_2611557_-\|septum-formation-inhibitor-Maf	gnl\|CDD\|376812	pfam02545, Maf, Maf-like protein. Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.	2.66633e-75
AP018515.1\|BBC81214.1\|2599512_2601336_+\|GTP-binding-protein-TypA	gnl\|CDD\|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
AP018515.1\|BBC81215.1\|2601619_2601928_+\|hypothetical-protein	gnl\|CDD\|236851	PRK11114, PRK11114, cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB.	1.52146e-07
AP018515.1\|BBC81231.1\|2613819_2616642_-\|ribonuclease-E	gnl\|CDD\|224447	COG1530, CafA, Ribonucleases G and E [Translation, ribosomal structure and biogenesis].	8.90634e-138
AP018515.1\|BBC81225.1\|2609433_2609592_-\|DNA-gyrase-inhibitor-YacG	gnl\|CDD\|234943	PRK01343, PRK01343, zinc-binding protein; Provisional.	1.31351e-14
AP018515.1\|BBC81228.1\|2611629_2612943_-\|histidinol-dehydrogenase	gnl\|CDD\|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
AP018515.1\|BBC81213.1\|2598878_2599499_-\|Fe2+-transport-protein-A-FeoA	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	1.34726e-15
AP018515.1\|BBC81221.1\|2606176_2607787_+\|MFS-transporter	gnl\|CDD\|181969	PRK09584, tppB, dipeptide/tripeptide permease DtpA.	6.31995e-112
AP018515.1\|BBC81218.1\|2603649_2604711_-\|ferredoxin--NADP(+)-reductase	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	4.53355e-62
AP018515.1\|BBC81229.1\|2612957_2613689_-\|ATP-phosphoribosyltransferase-catalytic-subunit	gnl\|CDD\|234971	PRK01686, hisG, ATP phosphoribosyltransferase catalytic subunit; Reviewed.	2.1456e-110
AP018515.1\|BBC81212.1\|2597016_2598882_-\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	2.8524e-154
AP018515.1\|BBC81226.1\|2609611_2610706_-\|ribonuclease,-partial	gnl\|CDD\|273254	TIGR00757, Ribonuclease_E/G-like_protein, ribonuclease, Rne/Rng family. This model describes ribonuclease G (formerly CafA, cytoplasmic axial filament protein A), the N-terminal domain of ribonuclease E in which ribonuclease activity resides, and related proteins. In E. coli, both RNase E and RNase G have been shown to play a role in the maturation of the 5' end of 16S RNA. The C-terminal half of RNase E (excluded from the seed alignment for this model) lacks ribonuclease activity but participates in mRNA degradation by organizing the degradosome. [Transcription, Degradation of RNA].	1.28489e-16
AP018515.1\|BBC81223.1\|2608679_2608979_+\|integral-membrane-protein,-YggT-family	gnl\|CDD\|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	2.64584e-07
AP018515.1\|BBC81220.1\|2604821_2606042_-\|isocitrate-dehydrogenase	gnl\|CDD\|236226	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase.	0

>AP018515.1|BBC81221.1|2606176_2607787_+|MFS-transporter
MQWLVFIHSKGSFPLPKRQVFAVLGTRSQNGQGFMTNTSSFTHRSRVQSFAVVLAIELWERFGYYGMQGILLLYMVQRLNLADAQANVLLGTLSAVIYAAPAIGGWVGDAVLGSRRTMLLGAVVLALGYGVLGLDSGGQLTLFVALAIVALGNGLFKANSANLVRRIYEGDNAQIDVAFTYYYMSINIGSMVSLLLTPWLQARLGWGPPFGVCAAGLVFGLASYGFFRKRLSTVGSAPDFSPLVWGRLVAVLAGMGVFVAVVVSILGSPMLGRICVWVAAIAVVVAWVLLYRRAAPQSRPGLRLAYLLIVQTMVYFVFYQQMVTSLTLFALRDVRSEFTLFGVPLFSLSAGQFQALNPVWIMLASPLLSWGYGQLEKRGYYLPVAEKFIAGFSLVALSFLIWWWSAAQSVAPISPWVMFWAYGALSVGELLISALGLAVVARYVPLNIGAFMMGSYCVSNGVAMYLGSMVANMAAVSGAVGGETVAAMLPVYASLFRSLFFLAVGCTVVFVVCLPFTRRWDAQHHAALGIKAGAKG
>AP018515.1|BBC81220.1|2604821_2606042_-|isocitrate-dehydrogenase
MAKIKVKNPVVEMDGDEMTRIIWHFIRERLILPYLDIDLKYYDLGIEHRDATDDKVTVEAAEATKRYGVAVKCATITPDEARVKEFGLKRMYRSPNGTIRNILDGTIFREPIICTNVPRLVPHWTQPIVIGRHAYGDIYRAAETKIPGPGKVTLTYVPENGGETVTLDVHDFKGPGVALGMHNTRASIEGFARASLSYGLNRGLPVYLSTKNTILKAYDGMFKDVFQEVYDKEFKAAFEKANLTYEHRLIDDMVACALKWKGGYVWACKNYDGDVESDIVAQGFGSLGLMTSVLLDPTGQVVEAEAAHGTVTRHYREHQKGKPTSTNPIASIFAWTRGLAYRGKFDDTPDVVHFAQTLEKVCVDTVEAGQMTKDLALLVGKGTTWLDTQPFLDVLDEGLRKALAKS
>AP018515.1|BBC81219.1|2604667_2604817_+|asparagine-synthetase-domain-containing-protein-1
MARGGLPVCPAADFNSVFCSSTAVDAMGGEQTKKGSATWALPYFKACCA
>AP018515.1|BBC81218.1|2603649_2604711_-|ferredoxin--NADP(+)-reductase
MKSAAGHTGRPPRAMTQTPLQTDVAIIGAGPTGLFAAFQCAMLRLNCLLIDVLPEIGGQCVALYPEKPIYDIPACPAVEGAQLIANLEQQLAPFNVPRLLKHRLESLSGHRGDFTLGTDKGAHIKAKAVIIAAGAGAFGPNRPPLDGLEDFENSGAVQYYVRRKADFEGRSIVIAGGGDSALDWALALKDKAEKLYLVHRRDRFRGAPESLRQLDEAVENGQIEKIVPYQLHALHGQNGALEAVEVVDLEGNTRKLHANTLLPFFGLATDLGPIARWGMDTVRSTIPVTPSSCETSLPGVFAIGDVATYPGKLKLILQGFSEAAMAAHSIYPIVNPDQALHFEYSTSKGVPNT
>AP018515.1|BBC81217.1|2603383_2603596_+|alcohol-dehydrogenase-2
MPHSWQFHVSQPSKATTREGGCLGVGRGQGHGQAGSQVILHRKGKGRRTGWPVPAATFPPLSIKNALVRL
>AP018515.1|BBC81216.1|2602034_2603294_-|D-amino-acid-dehydrogenase-small-subunit
MKVLVLGAGVIGTTSAWYLAKLGHEVTVIDRQPAPGLETSFANAGQVSPGYSSPWASPALPRLALKWMLQHNASPLVIRKRFDLAMFRFIQQVLKNCNAHAYSINKARMLRVADYSRDCLDTLREEIGLTYDDRQRGLIHLFRTDKQLDKARQDMKLLAESNIEHQLLTVPQILAREPGLTHAQGLLKAGLYLPGDQSGDAHIFTQRLAKRAEALGVKFLYNTTIKGLDATVDEVVSVRTSAGHFRAESYIVSMGSYSPLLLKPLGLRLPIYPVKGYSLTIPLTDETHAPLSTVNDESYKVAITRLGNRIRVGGTAELAGYSQRLSPDRRAGLELSFSELFGGGDLASAKYWTGLRPCTPDGTPIIGAAPGFKNLWLNTGHGTLGWTMACGSGRLIADLVHGRKTDIPALDLTLGRYTP
>AP018515.1|BBC81215.1|2601619_2601928_+|hypothetical-protein
MISRRLLAVVSTVALMGAAAPSFAQEAAAPAAPAATAPAAAAPAAPEAAAPAAAPAAEAGKEEAADQKGKKHHKHGGKKHHGHKKAKKAEGAADTAADSSAQ
>AP018515.1|BBC81214.1|2599512_2601336_+|GTP-binding-protein-TypA
MDIRNIAIIAHVDHGKTTLVDELLKQSGSFHEHQHVAERAMDSNDLERERGITILAKCTSVVWNNTRINIIDTPGHADFGGEVERILSMVDGAVVLVDSAEGALPQTKFVVGKALARGLKPIVVVNKIDRGDARPDEVHNEIFDLFASLGANDEQLDFPMLYASGRQGWADVELDGPRKDLSPMFELILKHVPAPALDKDKPFAMTATILENDNFLGRVLTGRVEQGRARVNMPVKVLRADGSTVETGRLTKLLSFRGLDRVAVEEVEAGDIVAVAGLSEATIPDTIAAPEVTEPLKAIPVDPPTLSMTFRLNDGPLGGREGKKVTSRQIRDRLFKETESNIAIRVSESPESEAFEVAGRGELQLGVLIETMRREGFELTIGRPRVLYQTNEETGEREEPYEEVMIDVDEPYSGVVVEKMSLRKGQMQDMRPSGGDKVRLTFIIPSRGLIGYHGEFLTDTRGTGIMNRLFHGYQAYAGPIEGRRNGSLISAEDGNTTTYSLFSLQDRGTLFVDAGEKVYVGMIIGEHSRENDLEVNGVREKKLTNMRASGKDDALFLTPPRRMSLEQAIAYIEDDELVEVTPSAIRLRKRYLDPNERKKRERKGDAG
>AP018515.1|BBC81213.1|2598878_2599499_-|Fe2+-transport-protein-A-FeoA
MSLRVVPPLSLQDWRLRFGIKSAGPVDKRQNAELHVKSSQGSQNTAWASLFCRSTPIKQTQNILRPLQAEQKHGHGHDLELRIILNIECYSTVQLDPLPSRIKPTVRLNQLPLRSAGVIDHIESLSPSDTIAQRLGELGFVPGEPVKVIAFGPLGGDPMAVEIGFTRFALRCAEANRVVLKDMPANPNAACPAHPHESSHTTAPQA
>AP018515.1|BBC81212.1|2597016_2598882_-|ferrous-iron-transporter-B
MSTQTPPLAPSQAAPLRVALVGNPNCGKTALFNQLTGSRQKVANYAGVTVERKAGRLLTPAGRKVTVLDLPGTYSLAATSPDEAVTRDVCRGVYKSEPAPDLLISVVAATNLRLHLRFMLELRQLGRPMLVVLNMVDAMRKQGLDIDVPRLQAELGVPVVTAVGVKRGGAANLLAALDTPIPPAPTPLPAGTDLHHEVRRIMALCVARTSERRQALEEKLDRWVLHPVWGMCILFVLLFIMFQAVFSWAQPFMDFLEEAMKQLGDFVGTLLPSGALQSLIVDGVIAGAGTVIVFLPQILILFLWILALEESGYLPRAAFMLDKLMASAGLSGRSFIPLLSSFACAVPGIMSTRTIQNPRDRMVTILIAPLMTCSARLPVYALLIGAFIPARRIGGIFNLQGLVLFALYGLAILSALLVARVMKRRDVEEHPLLLELPNYRLPGLQSLAIELWQRARIFLSRVGSIIVTLSVIMWALSSFPAPPAGATGPAIDYSLAGRIGHIMLPLFLPLGFNWQICVALIPGLAAREVAVSALATVYSVGASEADAASQLTPLLANQWSLATALSLLAWYVYAPQCFSTLAVIRRETGSWRFVAISAGYLFGLAYGVAFLTYHITRLITG
>AP018515.1|BBC81223.1|2608679_2608979_+|integral-membrane-protein,-YggT-family
MLFSLYMVLTRLLDIYCWILLLSCIFINLCMFGILDSRNQLVWKVGVFFSRVTEPVLGPIRRMLPNLGGVDFSPMIVLLGIQYIVQPLLWQVFRALIYR
>AP018515.1|BBC81224.1|2609065_2609194_+|hypothetical-protein-Abor_026_002
MTNAAPDKPSKTQQEKELDEALKESFPASDPPAQTDPDKPAD
>AP018515.1|BBC81225.1|2609433_2609592_-|DNA-gyrase-inhibitor-YacG
MCGKPAQHATRPFCSQRCADIDLGRWFTGQYRVPGPPVDEENIQKNERNDER
>AP018515.1|BBC81226.1|2609611_2610706_-|ribonuclease,-partial
MSVFLRLTFSPGEVRIAVTQDDKLLDYALWRPAAPDGVGDVYWARIATLAHSMGGAFIDLGTGEQGFLPLSSDVTPHTEGQCLAVQVTRAAQGGKGLRLRKLDTPPSPTPDKPGLLSRGPTPLARLAHIFADVALVADSPESAALIPPLLQPRRSKGFRPWPEAIAHACAALEEPIVTLPGGMQASITPTPALIAIDMDAPPTTTGWSKQTAQFAANRDALPALLHQIRLRNLSGAILIDPAGLAVRKRQALLEPVKAMLQADPLKPRCLGITGLGLIEMVRARIHPSLPELLNAPHGRALAALRTVLAQHPTATQLRCGLALLGALEADPQAVADCMRLRGKPFTLKLDPSLPDLAWIPQSND
>AP018515.1|BBC81227.1|2610702_2611557_-|septum-formation-inhibitor-Maf
MSKEDMIEFSGTVTELLPNAMFRVKLDNEHMILAHTSGKMRKNRIRVLAGDRVNVEMTPMTSPKVVSPSASSKTMTASGPTGTEGAIRPAFVLASASPRRLDLLAQLGVTPERVFPADIDETPARDEQPRPYVRRMAAEKAQKIASQITEPALVLSADTVVALGHRILPKAETIETARACLRKLSGRRHTVFTAIRCVPSAGWPEGCVSERVVESTVAFSRMTEQQIEALLATGDWQGKAGGYALQGHAAGFIRFISGSPSAVIGLPLFETAQLLRGQPGNWLP
>AP018515.1|BBC81228.1|2611629_2612943_-|histidinol-dehydrogenase
MKRLDIRDSGFEAEFSSLLAAREEQGQEVHGPVASILAQVRKDGDTALCALTEKFDRLPLSAEKLAFTPQEVEAARAQVSPDLLAALDVAATRIESFHRAQLPEGIRYTDDAGMTLGMRWIPLDAVGLYVPGGKAAYPSSVLMNAIPARVAGVERLAMCVPTPDGIINPLVLAAAHRAGVTEIYRVGGAQAVGAMAFGTKTIKPVDRIVGPGNAYVAEAKRQVFGHVGIDSIAGPSDVVVIADSATDPRLIALDLLAQAEHDELAQATLITPDAAFADTVIAAVETELKTLTRTAIASASWARNGAVLIVRSLEEAVTLANRLAPEHLELMVDDPESLFAHVRHAGAVFLGRYCPEAVGDYVGGPNHVLPTSRTARFASGLSVFDFLKRTTFLAGGPDALRRIGPAGVALAHAEGLEAHALSISARLDALAKTTPNA
>AP018515.1|BBC81229.1|2612957_2613689_-|ATP-phosphoribosyltransferase-catalytic-subunit
MTVPQPDQQNQRLPGTEETHTPLVLALPKGRILKAVAPLLQQSGLAPSDDCLGESSRKLRFPTQNPNVDVVRVRSFDVATFVASGGAQIGICGADVLMEFDYPEIYAPLDLGIGGCRISVAQPNTLPHDPAEWAQWSEVRAATKYPAITRRYFAQRGINANIVHLHGAMELAPMLGLSRLIVDLVDTGSTLRANGLREVETIAHITSRLIVNRTALKTRPEEISAIITQFRTALASQQQDQNS
>AP018515.1|BBC81230.1|2613685_2613832_-|hypothetical-protein
MAPLKPYATLGRYFLLPREGFTFEAAPGCARSAAVTHPFVLAARPEFS
>AP018515.1|BBC81231.1|2613819_2616642_-|ribonuclease-E
MDGNRLEDYDVEAAAKKQLKGNIYLARVIRVEPSLQAAFVEYGGNRHGFLAFSEIHPDYYQIPVADREKLLALQAEEEALIDADEDNEDTDAQDLNAEADDEDAEQSDEQETAEAEADGSENRRAPRRNGGPDYVGGETDTGEEALIQKRIARFLRNYRIQEVIRRRQVLLVQVVKEERGNKGAALTTYVSLAGRYCVLMPNALRGGGVSRKITSVADRRRLRDIISDLNLPRGMAMIVRTAGAQRPGPEITRDCEYLLHLWDDIRELTLQSVAPALIYEEASLVKRAIRDVYTREISEILVDGESGWKAARDFMRLLMPQHAEKVRLWNKENQPLFTHYHVEGHLDAMFSPVVSLRSGGYLVINQTEALVAIDVNSGKSTNQRNIEETAFRTNQEAADEVARQLRLRDLAGLIVIDFIDMESRRHNVMIERRLKEALRHDRARIQMGGISHFGLLEMSRQRLRPSVAEAVFAPCPHCQGTGMVRGIESSALHVLRSVEEEGARRRASAITVHVAPEIAFYILNNKRTWLAEIEKRHYMEVLFAPDSSLPAPEVRIERLQPARVQRAPAPIQPPLENVAIEHTPVEAPAELDEVEEPRQTATPENATAATPDEDEPRRRRRRRRRRGGNGNRDERTPQAEQHEQNTHANAPESEADEQPETYTVEEANGENLAPGRRRTRHSRVQRQPQQEVQVQVPIAQGPAPRQEQRRPSQVWQGPTPANPFGGSIDIFDLIENSTMQAEEARKAAPVAQPAKGEAAVVAPTPAPVAAPVQPAKVEAEPEEAEAQPARRRAPRRRRKTEETSTESNDLLADTAPVAVSPAAEADSVQDEDEAPKPRRRRAPRKTAEADAAPEASTEEKPRATRGRPRRKAEGTDEAADAAEAEKPAPRRRRAATKAEPAKTEAAAEPDAQAADPSIVQPIVIDDEQPAPRRRTGWWRR
>AP018515.1|BBC81232.1|2617179_2618118_+|N-acetylmuramoyl-L-alanine-amidase
MSVKPFSAPLPAAPEPHPHVAYKGYTVPLLSRRAVVGGGVAASLAGGQVFAAPHTHVLGHLPPPTPATPLHAPALTGKARPTPPLVMLDPGHGGKDPGAIGFSGTYEKHVAEAAAAELARQLMATGRYRVAMTRTSDRFIPLDGRVELAQKHGASLFISMHADALHNASVRGASVYTHSHGASDSQTAALARTENDADRFGGPLVQGASPEVQQILASLVTEEARRGSLHMANAVVSSFRSRINLLPHPQRHAAFAVLKSAQIPSVLVEMGFMSNRLDEAALRQAGHRAMVAGAMCTAVNRYFASAGVGLAG

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Crispr_ID: AP018515_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018515_2

2982518-2982733

Orphan

I-F

Consensus_repeat	Method
TTTCTGAGCTGCCTGTGCGGCAGTGAAG	CRISPRCasFinder
TTTCTGAGCTGCCTGTGCGGCAGTGAAG	CRT
CGCCTACTTCACTGCCGCACAGGCAGCTCAGAAAAATG	PILER-CR

3 spacers

The CRISPR arrays of AP018515_2

>merge|AP018515|2|2982518-2982733|CRISPRCasFinder,CRT,PILER-CR
TTTCTGAACTGCCTGTGCGCAGTGAAGTCATTAATTTTTGTAAACAATCGCTTGTCATTTTTCTGAGCTGCCTGTGCGGCAGTGAAGCAGGCGAACCCGGAACTGGCGGATTTCCGGGGTTTCTGAGCTGCCTGTGCGGCAGTGAAGTCGGCGCGTATTGCGCCATCATGATGGCGTCCTTTTTTCTGAGCTGCCTGTGCGGCAGTGAAGTAGAAG

>AP018515|2|2|2982518-2982727|CRISPRCasFinder
TTTCTGAACTGCCTGTGCGCAGTGAAGT	CATTAATTTTTGTAAACAATCGCTTGTCATT
TTTCTGAGCTGCCTGTGCGGCAGTGAAG	CAGGCGAACCCGGAACTGGCGGATTTCCGGGG
TTTCTGAGCTGCCTGTGCGGCAGTGAAG	TCGGCGCGTATTGCGCCATCATGATGGCGTCCTTT
TTTCTGAGCTGCCTGTGCGGCAGTGAAG

>AP018515|2|2|2982518-2982727|CRT
TTTCTGAACTGCCTGTGCGCAGTGAAGT	CATTAATTTTTGTAAACAATCGCTTGTCATT
TTTCTGAGCTGCCTGTGCGGCAGTGAAG	CAGGCGAACCCGGAACTGGCGGATTTCCGGGG
TTTCTGAGCTGCCTGTGCGGCAGTGAAG	TCGGCGCGTATTGCGCCATCATGATGGCGTCCTTT
TTTCTGAGCTGCCTGTGCGGCAGTGAAG

>AP018515|2|2|2982573-2982733|PILER-CR
CATTTTTCTGAGCTGCCTGTGCGGCAGTGAAGCAGGCG	AACCCGGAACTGGCGGATTTCCGGGG
TTTCTGAGCTGCCTGTGCGGCAGTGAAGTCGGCGCGTA	TTGCGCCATCATGATGGCGTCCTTT
TTTCTGAGCTGCCTGTGCGGCAGTGAAGTAGAAG

Protein	Signature genes	Signature genes Name	Protein_function
AP018515.1\|BBC81621.1\|2978516_2978663_-\|protein-toll	unknown	unknown	unknown
AP018515.1\|BBC81620.1\|2978382_2978496_-\|amino-acid-oxidase,-partial	unknown	unknown	unknown
AP018515.1\|BBC81634.1\|2987733_2987886_-\|hypothetical-protein	unknown	unknown	unknown
AP018515.1\|BBC81635.1\|2987981_2990456_-\|hypothetical-protein-Abor_035_007	unknown	unknown	unknown
AP018515.1\|BBC81628.1\|2983186_2984161_-\|D-glycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240626
AP018515.1\|BBC81630.1\|2985042_2985912_+\|DUF4412-domain-containing-protein	unknown	unknown	unknown
AP018515.1\|BBC81624.1\|2980752_2981145_-\|DUF2142-domain-containing-protein	unknown	unknown	gnl\|CDD\|370749
AP018515.1\|BBC81631.1\|2985908_2986604_+\|hypothetical-protein-Abor_035_005	unknown	unknown	unknown
AP018515.1\|BBC81632.1\|2986622_2987231_+\|hypothetical-protein-Abor_035_006	unknown	unknown	unknown
AP018515.1\|BBC81633.1\|2987248_2987644_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379224
AP018515.1\|BBC81623.1\|2979641_2980691_+\|2-nitropropane-dioxygenase	unknown	unknown	gnl\|CDD\|224981
AP018515.1\|BBC81622.1\|2978663_2979494_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378945
AP018515.1\|BBC81627.1\|2982951_2983137_-\|hypothetical-protein	unknown	unknown	unknown
AP018515.1\|BBC81636.1\|2990542_2993671_+\|glutamate-ammonia-ligase-adenylyltransferase	unknown	unknown	gnl\|CDD\|237612
AP018515.1\|BBC81619.1\|2977605_2978310_-\|hypothetical-protein	unknown	unknown	unknown
AP018515.1\|BBC81625.1\|2981272_2981398_+\|DUF2142-domain-containing-protein	unknown	unknown	unknown
AP018515.1\|BBC81618.1\|2977227_2977566_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|225984
AP018515.1\|BBC81626.1\|2981477_2982095_-\|membrane-protein	unknown	unknown	gnl\|CDD\|370749
AP018515.1\|BBC81629.1\|2984342_2984996_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
AP018515.1\|BBC81617.1\|2977086_2977203_+\|ubiquinol-cytochrome-c-reductase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
AP018515.1\|BBC81623.1\|2979641_2980691_+\|2-nitropropane-dioxygenase	gnl\|CDD\|224981	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only].	1.5736e-66
AP018515.1\|BBC81622.1\|2978663_2979494_+\|hypothetical-protein	gnl\|CDD\|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	5.06002e-20
AP018515.1\|BBC81624.1\|2980752_2981145_-\|DUF2142-domain-containing-protein	gnl\|CDD\|370749	pfam09913, DUF2142, Predicted membrane protein (DUF2142). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.40879e-08
AP018515.1\|BBC81636.1\|2990542_2993671_+\|glutamate-ammonia-ligase-adenylyltransferase	gnl\|CDD\|237612	PRK14108, PRK14108, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase.	0
AP018515.1\|BBC81628.1\|2983186_2984161_-\|D-glycerate-dehydrogenase	gnl\|CDD\|240626	cd05301, GDH, D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH). D-glycerate dehydrogenase (GDH, also known as hydroxypyruvate reductase, HPR) catalyzes the reversible reaction of (R)-glycerate + NAD+ to hydroxypyruvate + NADH + H+. In humans, HPR deficiency causes primary hyperoxaluria type 2, characterized by over-excretion of L-glycerate and oxalate in the urine, possibly due to an imbalance in competition with L-lactate dehydrogenase, another formate dehydrogenase (FDH)-like enzyme. GDH, like FDH and other members of the D-specific hydroxyacid dehydrogenase family that also includes L-alanine dehydrogenase and S-adenosylhomocysteine hydrolase, typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form, despite often low sequence identity. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	3.59375e-131
AP018515.1\|BBC81633.1\|2987248_2987644_-\|hypothetical-protein	gnl\|CDD\|379224	pfam13502, AsmA_2, AsmA-like C-terminal region. This family is similar to the C-terminal of the AsmA protein of E. coli.	1.25014e-07
AP018515.1\|BBC81618.1\|2977227_2977566_-\|oxidoreductase	gnl\|CDD\|225984	COG3453, COG3453, Uncharacterized protein conserved in bacteria [Function unknown].	2.97163e-34
AP018515.1\|BBC81626.1\|2981477_2982095_-\|membrane-protein	gnl\|CDD\|370749	pfam09913, DUF2142, Predicted membrane protein (DUF2142). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.74412e-19
AP018515.1\|BBC81629.1\|2984342_2984996_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.0141e-107

>AP018515.1|BBC81626.1|2981477_2982095_-|membrane-protein
MDYFVLLSPPFQVADEPNHFMRVLQIAQGNLVGIRQSKTESGALLPMTAPMFAASFNKLPFAPQEKVTADMLVKAMSLRWPSSLTFVSLPNTVIYPPTSYVGAVTGVLWAHTLHATPFGTLYLARIGNLVINVGVSVCALLLSPEAGLFLVAILILPMSISLMASCSQDGMVLALMALGIACTLRWFREHNEKNALCLLVSAAFL
>AP018515.1|BBC81625.1|2981272_2981398_+|DUF2142-domain-containing-protein
MKINCSEADAPSGALVVIVGLMPQKNHTENTITLLKQDVKA
>AP018515.1|BBC81624.1|2980752_2981145_-|DUF2142-domain-containing-protein
MLVKIFLIFITLTFLLSAKGFSNKKLSNLRISGLIILILSTIFGIFTSLYLTWTPVGRPVIEGVQGRYFLPVVMLVALAPSLIKNTQDTQKLLPTKIYEIQKKAAVNLSVIIFMLFCYFTLYLYLLNRYW
>AP018515.1|BBC81623.1|2979641_2980691_+|2-nitropropane-dioxygenase
MLHRLGVRLPLFQAPMAGVSTPALAAAVCQAGGLGALGLGAATVAQAQMQIAELQAKTKKPFNLNFFVHAPAVQNTALEHAWCKAFEPLFAQFGAHPPTPLREIYTSLHQDEAMQRLLLAVRPAVTSFHFGVPPQALVRALKAAGVFLVATATCVEEAKLLEKAGMDALIAQGIEAGGHRGIFETTQPDTALSTMVLTQLLHKTCQIPIIAAGGIMTGHAIAAALKVGATAAQLGTAFIGCPESAANAAYRTALTGPGAFKTEMVTALSGRLARSLPNKFTAFAQTLAGQACPAYPLAYDMAKALNTAAQDQGEYGFAAQWAGQGAPLARSLPAASLMASLKAELEQKI
>AP018515.1|BBC81622.1|2978663_2979494_+|hypothetical-protein
MSTKDAASNDVVSLTLSGQDLTELEKALAQVEAGKGVLVRLADLMGGAVGHAARLGLRGLGMAPGMEQKLRGLAETAITRAFDAAILGMRPVDENPAPEKIWRTPALQAAVAVSGAVGGFTGLAGLGPDIGFTTLTIMREIARIAREEGEDLSNPDARIACLEVFALRAFPNVKQGEENELGYFSARALLRGRPVVMLISEVASHYGLALGHKVSLQLMPVAGALCGASLNTAFLNHYRALARAHFTIRRLEREHGPVVRDTALAMRDQGKGEASF
>AP018515.1|BBC81621.1|2978516_2978663_-|protein-toll
MCPFSFWLHPLTGGGASAPARGLTLLWWLHFIIPPAKATQRPGFVLQQ
>AP018515.1|BBC81620.1|2978382_2978496_-|amino-acid-oxidase,-partial
MPYYPQPNAKLPGFAITRLVAALHLAQTQNQTRTPAL
>AP018515.1|BBC81619.1|2977605_2978310_-|hypothetical-protein
MTDTRHSSLPLSPRTRFSWRNVMRAGSVLAVLAVAACAQSPEKKAEQAALEAAKTDPDFCYSAKYDGLLVQAWQRAHATNAATQQDTGKADPATLPPVSVNDATVMPESSVPPYSRRSCRMSIKVGNAAPESGFLAFTYLTRNGQTQSALAEWFPDSVVTEKYDATMEQIKAGVDMSNPDLKTCLARYPGFETESSDPMVKKAAFDLRAHLIRRCMANKVALRNLYSDLYFIHR
>AP018515.1|BBC81618.1|2977227_2977566_-|oxidoreductase
MSTFRKLSENFVVGPQISLDDVPAIQEAGFKTIICTRPDAEDPGQPTAQEIGEAAAAVGLSFISIPVQAGQAPSSDAVIEMQEALNTLPGPVLCYCRSGNRAGQLWTRATQG
>AP018515.1|BBC81617.1|2977086_2977203_+|ubiquinol-cytochrome-c-reductase
MADFMLYGRLAGASLINKPIAKGRAPVTVARPLFNRAV
>AP018515.1|BBC81627.1|2982951_2983137_-|hypothetical-protein
MQMTLRLACLIGIALAGVLRFVDPHYHLTAEIVGAGFLITALVATVILDETAPAGISASKK
>AP018515.1|BBC81628.1|2983186_2984161_-|D-glycerate-dehydrogenase
MSADKPRLIRSVRLLAAAEKRIEAEFLAPPSPATPLNTAAILKLAHEFQPTAVLVTHHAPLKGQDIAALPDCVKLVATVSVGLDHLDVPALLARGIAVSNTPDVLTDCNADLTMMLIIAACRRAAEYYTLMKKGWGHTLGMDEMLGHRVTGKTLGIIGMGRIGQAVARRAHGFEMNVLYHNRRQLDPAQEEGATYYASLEEMLPKCNILSLHLPAAPNGQPIMTARTLGLLPRGSVLVNAARGALIDETALIDALRSGQLAGAGLDVYRNEPNPDPRILALPNVFMTPHVGSATVETRTAMCMLALDNVAALVAGTPLPSPVTA
>AP018515.1|BBC81629.1|2984342_2984996_+|leucyl/phenylalanyl-tRNA--protein-transferase
MAEQALTPELMLGAYAVGLFPMAANAEDTELQWYDPDPRGIIPLEGFHLPRRLQRTVLSDKFSVTVNQDFAGVMQGCATPAPGREETWINQEIFTLFCALHKMGYAHSVECRLNGELVGGLYGVALGGAFFGESMFSRVTDASKVALVHLVARLRLCGFSVLDTQFGTDHLARFGGVEIPAQDYKASLERAVQMLPCWRDTVPDDVIKAEIKAMRGA
>AP018515.1|BBC81630.1|2985042_2985912_+|DUF4412-domain-containing-protein
MTISQRGRKPSLLTLCGLLASAPFLVPSVGLSAPAPAAASGQPEQTAPATVADHPRLSPGRDATIDYVFQPQPPPELVQAGKVPSGPLPERHVQVLFSGDGGLMRIRYLKDMTDTNPRGSVILNRAAQEVLVILDDRKIYTRLVQQEVARSPFLLDMSMQFVRKNQAQVSGQPCTVWGVQSPQGKGTACVTDDGFILEQDGVDVDGLHGHLKALHVSYDDVPASAFMPPSGYQEVTAHAPQAGTAQNDGPQEGAIPAPATSPVPGVGPTTRMPSGTDNPQGPQPSEATP
>AP018515.1|BBC81631.1|2985908_2986604_+|hypothetical-protein-Abor_035_005
MSGFKTTLLRHTGVAVVLAAGVAMLPLQAQAQKAPQSPVAPESLYGAGATPNIAAPDSTAVCDRDGPCITPATDADIVYELTSPVGDAAIKQRMRWQVAALKQRLDPENTSVYMVTSWPEHTLSVVDLSRKRFSVMPAPSQGLTPPGHIAMTGTYARLGSSIVAGERCTVWRTKDTDGHASDVCYTPDGLLLQVAQGQQITVRALSVSRATQPDTVFTIPAGLKQEAPATP
>AP018515.1|BBC81632.1|2986622_2987231_+|hypothetical-protein-Abor_035_006
MRLLSMQEHGMVKQTVFGTCALALGTLWGVVAMGQAAQAQTPVTSNGLGTVALSTNGQGSISICANSLSKGAETDLLVVPSGTVFAQQASTGKQGAQAFVTTETVTLTHMQPCGLTDGSTLVSHTRHWLVNPVKAGADVVFHTVGEVSGNGLDTSFDDETLGLRAAFKNGSIIAHVQGPLHDTVYLTESAADIEDPDAPQKP
>AP018515.1|BBC81633.1|2987248_2987644_-|hypothetical-protein
MLLARNLSLYGWLNGRKSPEFEVTHLSLPVSFSDGVLRIHDGSTGNDALGATLEGDIDLDHGKLDLDGTVVPIFAFNKLPGKLPGVGRLFSPEKNGGFLAMTFGLSGKLDKPDFHVNPYSVLLPGVLRKIF
>AP018515.1|BBC81634.1|2987733_2987886_-|hypothetical-protein
MAFSMRGPTPVAMHLTPNGTKRSLHVVVPDMGEFLSAFNILPNVKGGRPP
>AP018515.1|BBC81635.1|2987981_2990456_-|hypothetical-protein-Abor_035_007
MRVCALSLVIIIVLPVLAVAALLVRMLFGPVNITPAIRPFLPLTVLEGAPGQPPAAKLTLGRAELRWNSLTQGWRAPFLVSLDTVQLLKANNDTPDFIRSAQATLDPLALVHGTVGLRTLDVRGVRLALRRKPDGTVGLAAQDSAPTQAKHSPSSPSVGPLLDIEQLSLHDAIITMDDQLTGTHWTASPVEGTLHIAPEHGKYGITGAGNLTITGQKTGAQLKLAATGTRQPDHTVKWLITLAPTQPASFAKVAPALASIKNTVGLSATATFAGAQKSAWLLPNTLDVAVEVGAGALEVAHSPYLLKHASTQVHLALNQHSTTHTPAILTIQALTLDLLDPTQPNTPEKGITVQGQGVLNASDLFSPQSLSGQVGVAIPQVDFANIAQFWPQTAAKGGRRWVSENITTGLAHNLHVGLTVHSATGWKGLNVTGATGGVDASGLTVHWLRPISPLHELEAHLEIQGLDTLKINFDHGYQLIDLADKNVGARGIGRVEAGPGSMTIAGLTKKDQTGTIATQLHGNLRDILALLTENRLHLLSRHPLSFTKPTGIAAVDFTLTLPLDSDVTTDQMTVDAHAHVTHAHLGNVVMNRAITDGAFNLSATTEKMDLAGHAAVGGFPADLSYFMDFRSLKPTDVAEKAHVMATITPASAMAAGIAVGNHFDGKAKLGVDYTRLANKQATVNLALNLTPAQVLIPLWHKAAGRPAQVSAELALLDGHITGVNKLQASGPNLDVRGQAAIKPNAAPELLVSSFRIDRSTGHARLVLPYATQDKTIRVGVYADTLDLSPLMETDPAAPLKKRAATMCQRPQVVRYTALRAMRGT
>AP018515.1|BBC81636.1|2990542_2993671_+|glutamate-ammonia-ligase-adenylyltransferase
MPLVTQPSFKDIRQPRSARTPRLWPDAMWPAAANTQAAAHFEEDMRAALQESGQTDVLDMPGAAALLTCLGGNSPYLSDLARQDTDFFVTLLQKGPSACATEAFATLAECDFTAERTHVAASLRQAKKQVALLCAIADIGGFWPLEDVTQALSRLAETTLEVALKHLLWAAHDSGQIQLKDPKRPTYGCGFFVLAMGKLGARELNFSSDIDLMVLYDPSGYKQPDAVRRVFIRMTSDLVSLMEARDANGYVFRTDLRLRPDPASTPPAVSVQAAMVYYESLGQTWERAAMIKARPVAGDLTLGRSFLEAIRPFVWRRHLDFALIDDIHTMKARIDRYRNTGRTGLATLAESTVADPAASMQWLLGHNLKLGQGGIREIEFIAQAMQLVWGGRDPTLRDKTTFGALKKLVKLAYLPREEAEVLARTYRLLRDAEHRLQMRADYQTHSLPEQADAFNAFAVFMNYSDGEALALDLLPRMREARRIFERHFVTQAQPAEEQDKTLLAVAPDDENSPILLQNVGFSPEQAVEAAQVLARWQGNSLRALRSERAHALLRNLLPALLASFATRSNPLACLRRFDALLARQHAGVQLLSLFERNPALIDRIAALFDASAFLADHLADKPSALEGLLEPEPEEGRNVLARLRQLAAEVEDTEMLVTALRPLLRGEEFRLSVAVIEGRMSEDEAERARTALADTIMIVLKQAVEKDHIRRYGRVPGGGMAVIALGKAGSREMMPGSDLDLLLVFDHPEAQQMSVVPQTPRAKTPEGFLLPAPRSVSVGQYYTRLAHAFIAALTAPGPEGPLYAVDMRLRPSGAAGPVAAARQGFLQYHRDAAWTWERMALTRARIIAAPIALRHVLSADIAAILEGKLRKPEPTKAEVLEDARAMRARLARDLPATSPWDIKRRSGGLMEVEFIGQTLQLVVADKTVRDTCTRKALVKLGKAGVLNSAQTKLLLQADSQWRRLQCLLRLLCGPVPPLDLEKELAPPSQAILLRAMKVKTLPDLISQTSALARAVRACFAQTIGTVQEGDAFAEVMLEESGI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
AP018515_1	1.11\|2608385\|32\|AP018515\|CRISPRCasFinder,CRT	2608385-2608416	32	MH622937	Myoviridae sp. isolate ctcg_2, complete genome	33024-33055	1	0.969
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NZ_CP044550	Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence	54258-54283	3	0.885
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NZ_CP042167	Burkholderia contaminans strain ZCC plasmid unnamed1, complete sequence	225188-225213	4	0.846
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NZ_CP028810	Burkholderia contaminans strain SK875 plasmid p875, complete sequence	180452-180477	4	0.846
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	6385-6410	5	0.808
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NZ_CP045386	Ruegeria sp. THAF33 plasmid pTHAF33_b, complete sequence	126469-126494	5	0.808
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NC_006569	Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence	407633-407658	5	0.808
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	KY697807	Microcystis phage MACPNOA1, complete genome	23291-23322	6	0.812
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP044550	Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence	54258-54289	6	0.812
AP018515_2	2.4\|2982611\|26\|AP018515\|PILER-CR	2982611-2982636	26	NZ_CP010862	Marinovum algicola DG 898 plasmid pMaD7	106143-106168	6	0.769
AP018515_1	1.1\|2607964\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2607964-2607995	32	NZ_CP016080	Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence	324116-324147	7	0.781
AP018515_1	1.3\|2608084\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608084-2608115	32	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	454876-454907	7	0.781
AP018515_1	1.3\|2608084\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608084-2608115	32	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	48665-48696	8	0.75
AP018515_1	1.6\|2608267\|32\|AP018515\|PILER-CR	2608267-2608298	32	NZ_CP016850	Pseudomonas sp. TMW 2.1634 plasmid pL21564-1, complete sequence	60104-60135	8	0.75
AP018515_1	1.9\|2608264\|32\|AP018515\|CRISPRCasFinder,CRT	2608264-2608295	32	NZ_CP016850	Pseudomonas sp. TMW 2.1634 plasmid pL21564-1, complete sequence	60104-60135	8	0.75
AP018515_2	2.1\|2982546\|31\|AP018515\|CRISPRCasFinder,CRT	2982546-2982576	31	NZ_CP043762	Paenibacillus sp. 37 plasmid pART37, complete sequence	42635-42665	8	0.742
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP045386	Ruegeria sp. THAF33 plasmid pTHAF33_b, complete sequence	126469-126500	8	0.75
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP042167	Burkholderia contaminans strain ZCC plasmid unnamed1, complete sequence	225188-225219	8	0.75
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP028810	Burkholderia contaminans strain SK875 plasmid p875, complete sequence	180446-180477	8	0.75
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	402888-402919	9	0.719
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	408260-408291	9	0.719
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	687446-687477	9	0.719
AP018515_1	1.6\|2608267\|32\|AP018515\|PILER-CR	2608267-2608298	32	NC_009339	Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence	92284-92315	9	0.719
AP018515_1	1.6\|2608267\|32\|AP018515\|PILER-CR	2608267-2608298	32	NC_008703	Mycobacterium sp. KMS plasmid pMKMS01, complete sequence	265625-265656	9	0.719
AP018515_1	1.9\|2608264\|32\|AP018515\|CRISPRCasFinder,CRT	2608264-2608295	32	NC_009339	Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence	92284-92315	9	0.719
AP018515_1	1.9\|2608264\|32\|AP018515\|CRISPRCasFinder,CRT	2608264-2608295	32	NC_008703	Mycobacterium sp. KMS plasmid pMKMS01, complete sequence	265625-265656	9	0.719
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP041349	Komagataeibacter xylinus strain CGMCC 17276 plasmid pA, complete sequence	191815-191846	9	0.719
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP021468	Komagataeibacter europaeus strain SRCM101446 plasmid pKE1446-1	132775-132806	9	0.719
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP004365	Komagataeibacter xylinus E25 plasmid pGX5, complete sequence	213239-213270	9	0.719
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NC_016037	Komagataeibacter medellinensis NBRC 3288 plasmid pGXY010, complete sequence	56805-56836	9	0.719
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP023038	Komagataeibacter saccharivorans strain CV1 plasmid unnamed2, complete sequence	140187-140218	9	0.719
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP050140	Komagataeibacter rhaeticus strain ENS 9a1a plasmid pENS1, complete sequence	4823-4854	9	0.719
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	15912-15943	10	0.688
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	15912-15943	10	0.688
AP018515_1	1.4\|2608144\|32\|AP018515\|PILER-CR,CRISPRCasFinder,CRT	2608144-2608175	32	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	130729-130760	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	6330-6361	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP030100	Roseovarius sp. AK1035 plasmid unnamed, complete sequence	123686-123717	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP021126	Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence	6327-6358	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP020332	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM259, complete sequence	176580-176611	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	6330-6361	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP010859	Marinovum algicola DG 898 plasmid pMaD4, complete sequence	142692-142723	10	0.688
AP018515_2	2.2\|2982605\|32\|AP018515\|CRISPRCasFinder,CRT	2982605-2982636	32	NZ_CP020475	Roseovarius mucosus strain SMR3 plasmid pSMR3-1, complete sequence	153104-153135	10	0.688
AP018515_1	1.6\|2608267\|32\|AP018515\|PILER-CR	2608267-2608298	32	NZ_CP021133	Pseudomonas fragi strain NMC25 plasmid unnamed1, complete sequence	37936-37967	11	0.656
AP018515_1	1.7\|2608327\|33\|AP018515\|PILER-CR	2608327-2608359	33	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	453291-453323	11	0.667
AP018515_1	1.9\|2608264\|32\|AP018515\|CRISPRCasFinder,CRT	2608264-2608295	32	NZ_CP021133	Pseudomonas fragi strain NMC25 plasmid unnamed1, complete sequence	37936-37967	11	0.656
AP018515_1	1.10\|2608324\|33\|AP018515\|CRISPRCasFinder,CRT	2608324-2608356	33	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	453291-453323	11	0.667

1. spacer 1.11|2608385|32|AP018515|CRISPRCasFinder,CRT matches to MH622937 (Myoviridae sp. isolate ctcg_2, complete genome) position: , mismatch: 1, identity: 0.969

caaaactcccgcgccacagggactttgcgggc	CRISPR spacer
caaaactcccgcgccacagggacttcgcgggc	Protospacer
*************************.******

2. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NZ_CP044550 (Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence) position: , mismatch: 3, identity: 0.885

aacccggaactggcggatttccgggg	CRISPR spacer
aacccggaactggtggatttccagcg	Protospacer
*************.********.* *

3. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NZ_CP042167 (Burkholderia contaminans strain ZCC plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

aacccggaactggcggatttccgggg	CRISPR spacer
aacccggaactggtcgatttccgccg	Protospacer
*************. ********  *

4. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NZ_CP028810 (Burkholderia contaminans strain SK875 plasmid p875, complete sequence) position: , mismatch: 4, identity: 0.846

aacccggaactggcggatttccgggg	CRISPR spacer
aacccggaactggtcgatttccgccg	Protospacer
*************. ********  *

5. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 5, identity: 0.808

aacccggaactggcggatttccgggg	CRISPR spacer
aacccggaacttgcggatttcaccag	Protospacer
*********** *********   .*

6. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NZ_CP045386 (Ruegeria sp. THAF33 plasmid pTHAF33_b, complete sequence) position: , mismatch: 5, identity: 0.808

aacccggaactggcggatttccgggg	CRISPR spacer
aacccggaactggtggatttcacccg	Protospacer
*************.*******    *

7. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NC_006569 (Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.808

aacccggaactggcggatttccgggg	CRISPR spacer
aacccggaactggtggatttcacccg	Protospacer
*************.*******    *

8. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to KY697807 (Microcystis phage MACPNOA1, complete genome) position: , mismatch: 6, identity: 0.812

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
acacggccacgcgcaccttcgcccaggccgcg	Protospacer
*.* ***** *************** ****

9. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP044550 (Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence) position: , mismatch: 6, identity: 0.812

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
gacgagaacccggaactggtggatttccagcg	Protospacer
 * * **************.********.* *

10. spacer 2.4|2982611|26|AP018515|PILER-CR matches to NZ_CP010862 (Marinovum algicola DG 898 plasmid pMaD7) position: , mismatch: 6, identity: 0.769

aacccggaactggcggatttccgggg	CRISPR spacer
ttcccggaactggcggatttctacga	Protospacer
  *******************.. *.

11. spacer 1.1|2607964|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016080 (Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence) position: , mismatch: 7, identity: 0.781

-tgtccgtaatcaacacggcgcaaggcaccctg	CRISPR spacer
gcgttc-cgatcaagacggcgcaaggcacgctg	Protospacer
 .**.* ..***** ************** ***

12. spacer 1.3|2608084|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 7, identity: 0.781

-tagaccgcgcgtaaagttggtcagcgggttgt	CRISPR spacer
gccgagcg-gcgtgaagttggtcagcgtgttga	Protospacer
 . ** ** ****.************* ****

13. spacer 1.3|2608084|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 8, identity: 0.75

tagaccg--cgcgtaaagttggtcagcgggttgt	CRISPR spacer
--gcccagcggcgtgaagttggtcagcgtgttga	Protospacer
  * **.   ****.************* ****

14. spacer 1.6|2608267|32|AP018515|PILER-CR matches to NZ_CP016850 (Pseudomonas sp. TMW 2.1634 plasmid pL21564-1, complete sequence) position: , mismatch: 8, identity: 0.75

--acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
gtattca--acaccaacggcggcactgtcgatga	Protospacer
  *..**  .****** *** ************

15. spacer 1.9|2608264|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP016850 (Pseudomonas sp. TMW 2.1634 plasmid pL21564-1, complete sequence) position: , mismatch: 8, identity: 0.75

--acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
gtattca--acaccaacggcggcactgtcgatga	Protospacer
  *..**  .****** *** ************

16. spacer 2.1|2982546|31|AP018515|CRISPRCasFinder,CRT matches to NZ_CP043762 (Paenibacillus sp. 37 plasmid pART37, complete sequence) position: , mismatch: 8, identity: 0.742

cattaatttttgtaaacaatcgcttgtcatt	CRISPR spacer
tttccatttttataaacaatagcttgtccat	Protospacer
. *. ******.******** *******  *

17. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP045386 (Ruegeria sp. THAF33 plasmid pTHAF33_b, complete sequence) position: , mismatch: 8, identity: 0.75

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
gggccgaacccggaactggtggatttcacccg	Protospacer
 .* ***************.*******    *

18. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP042167 (Burkholderia contaminans strain ZCC plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
gaagtaaacccggaactggtcgatttccgccg	Protospacer
 *.*..*************. ********  *

19. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP028810 (Burkholderia contaminans strain SK875 plasmid p875, complete sequence) position: , mismatch: 8, identity: 0.75

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
gaagtaaacccggaactggtcgatttccgccg	Protospacer
 *.*..*************. ********  *

20. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 9, identity: 0.719

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
cccccgccaagcgcaccctcgcccttgccggc	Protospacer
 .   ************.****** *****..

21. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 9, identity: 0.719

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
ataaggccatgcgcaacttcgccgacaaggcc	Protospacer
********* ***** ******* *..  * .

22. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 9, identity: 0.719

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
ctctggccgagcgcaccttcgccgatgatgcc	Protospacer
 *  ****.************** *** .* .

23. spacer 1.6|2608267|32|AP018515|PILER-CR matches to NC_009339 (Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence) position: , mismatch: 9, identity: 0.719

acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
taccagcgcaccgagggccgcgctgtgcaccg	Protospacer
  **********.********.****  *.

24. spacer 1.6|2608267|32|AP018515|PILER-CR matches to NC_008703 (Mycobacterium sp. KMS plasmid pMKMS01, complete sequence) position: , mismatch: 9, identity: 0.719

acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
taccagcgcaccgagggccgcgctgtgcaccg	Protospacer
  **********.********.****  *.

25. spacer 1.9|2608264|32|AP018515|CRISPRCasFinder,CRT matches to NC_009339 (Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence) position: , mismatch: 9, identity: 0.719

acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
taccagcgcaccgagggccgcgctgtgcaccg	Protospacer
  **********.********.****  *.

26. spacer 1.9|2608264|32|AP018515|CRISPRCasFinder,CRT matches to NC_008703 (Mycobacterium sp. KMS plasmid pMKMS01, complete sequence) position: , mismatch: 9, identity: 0.719

acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
taccagcgcaccgagggccgcgctgtgcaccg	Protospacer
  **********.********.****  *.

27. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP041349 (Komagataeibacter xylinus strain CGMCC 17276 plasmid pA, complete sequence) position: , mismatch: 9, identity: 0.719

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
agggcgaacccggaactgctggattgcagctc	Protospacer
 .**************** .***** * *

28. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP021468 (Komagataeibacter europaeus strain SRCM101446 plasmid pKE1446-1) position: , mismatch: 9, identity: 0.719

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
agggcgaacccggaactgctggattgcagctc	Protospacer
 .**************** .***** * *

29. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP004365 (Komagataeibacter xylinus E25 plasmid pGX5, complete sequence) position: , mismatch: 9, identity: 0.719

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
agggcgaacccggaactgctggattgcagctc	Protospacer
 .**************** .***** * *

30. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NC_016037 (Komagataeibacter medellinensis NBRC 3288 plasmid pGXY010, complete sequence) position: , mismatch: 9, identity: 0.719

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
agggcgaacccggaactgctggattgcagctc	Protospacer
 .**************** .***** * *

31. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP023038 (Komagataeibacter saccharivorans strain CV1 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
agggcgaacccggaactgctggattgcagctc	Protospacer
 .**************** .***** * *

32. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP050140 (Komagataeibacter rhaeticus strain ENS 9a1a plasmid pENS1, complete sequence) position: , mismatch: 9, identity: 0.719

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
agggcgaacccggaactgctggattgcagctc	Protospacer
 .**************** .***** * *

33. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 10, identity: 0.688

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
ggctggccaagagaaccttcgcccatgcgatc	Protospacer
.   ******* * ************** . .

34. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 10, identity: 0.688

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
ggctggccaagagaaccttcgcccatgcgatc	Protospacer
.   ******* * ************** . .

35. spacer 1.4|2608144|32|AP018515|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 10, identity: 0.688

ataaggccaagcgcaccttcgcccatgccgat	CRISPR spacer
cctcgctcaagcgcaccttcgaccaggccggc	Protospacer
 .  * .************** *** ****..

36. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaacccggaacttgtggatttcaccag	Protospacer
 .  ************* *.*******   .*

37. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP030100 (Roseovarius sp. AK1035 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaaccccgaactggtggatttcacccg	Protospacer
 .  ******* *******.*******    *

38. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP021126 (Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaacccggaacttgtggatttcaccag	Protospacer
 .  ************* *.*******   .*

39. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP020332 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM259, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaaccccgaactggtggatttcacccg	Protospacer
 .  ******* *******.*******    *

40. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaacccggaacttgtggatttcaccag	Protospacer
 .  ************* *.*******   .*

41. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP010859 (Marinovum algicola DG 898 plasmid pMaD4, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaacccggagctggtggatttcacccg	Protospacer
 .  **********.****.*******    *

42. spacer 2.2|2982605|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP020475 (Roseovarius mucosus strain SMR3 plasmid pSMR3-1, complete sequence) position: , mismatch: 10, identity: 0.688

caggcgaacccggaactggcggatttccgggg	CRISPR spacer
ggcccgaaccccgaactggtggatttcacccg	Protospacer
 .  ******* *******.*******    *

43. spacer 1.6|2608267|32|AP018515|PILER-CR matches to NZ_CP021133 (Pseudomonas fragi strain NMC25 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
gtgttcaacaccaacggcggcactgtcgatga	Protospacer
.. .   .****** *** ************

44. spacer 1.7|2608327|33|AP018515|PILER-CR matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 11, identity: 0.667

agaggcagcgctggcaccgatcagcgtgccaaa	CRISPR spacer
cgaggcagcgttggcgccgatcagcagcttcgt	Protospacer
 *********.****.*********.  .. .

45. spacer 1.9|2608264|32|AP018515|CRISPRCasFinder,CRT matches to NZ_CP021133 (Pseudomonas fragi strain NMC25 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

acccagcgcaccaagggccgcactgtcgatgt	CRISPR spacer
gtgttcaacaccaacggcggcactgtcgatga	Protospacer
.. .   .****** *** ************

46. spacer 1.10|2608324|33|AP018515|CRISPRCasFinder,CRT matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 11, identity: 0.667

agaggcagcgctggcaccgatcagcgtgccaaa	CRISPR spacer
cgaggcagcgttggcgccgatcagcagcttcgt	Protospacer
 *********.****.*********.  .. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

809475 : 817102

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBC79218.1\|809475_810126_-	hydroxyacid dehydrogenase	A0A2K9L339	Tupanvirus	1.6e-41	43.1
BBC79219.1\|810119_810539_-	hydroxyacid dehydrogenase	M1PHA2	Moumouvirus	1.2e-21	41.9
BBC79220.1\|810550_810739_-	hypothetical protein	NA	NA	NA	NA
BBC79221.1\|810765_812484_+	DNA helicase	NA	NA	NA	NA
BBC79222.1\|812453_813770_+	DNA helicase	A0A2P1N0K5	Streptomyces_phage	3.9e-10	32.6
BBC79223.1\|813901_814105_-	cold-shock DNA-binding domain-containing protein	A0A1W6JNX5	Morganella_phage	1.1e-09	52.0
BBC79224.1\|814233_814902_-	carboxymethylenebutenolidase	NA	NA	NA	NA
BBC79225.1\|815220_815406_+	molecular chaperone GroES	A0A221S4G8	uncultured_virus	2.5e-08	51.7
BBC79226.1\|815461_817102_+	molecular chaperone GroEL	A0A219YK78	uncultured_virus	2.8e-175	62.1

DBSCAN-SWA_2

1036791 : 1045004

Synechococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBC79473.1\|1036791_1037463_+	3'-5' exonuclease	K7XYU9	uncultured_Mediterranean_phage	8.6e-14	36.8
BBC79474.1\|1037490_1038516_+	arabinose-5-phosphate isomerase KpsF/GutQ	A0A2P0VNK5	Tetraselmis_virus	4.3e-33	32.2
BBC79475.1\|1038508_1039249_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
BBC79476.1\|1039251_1040277_+	organic solvent tolerance protein	NA	NA	NA	NA
BBC79477.1\|1040279_1041095_+	ABC transporter	A0A2H4PQG7	Staphylococcus_phage	1.5e-23	30.4
BBC79478.1\|1041111_1041387_-	hypothetical protein	NA	NA	NA	NA
BBC79479.1\|1041419_1041533_+	Homeobox protein Meis2	NA	NA	NA	NA
BBC79480.1\|1041720_1042335_+	30S ribosomal protein S30	NA	NA	NA	NA
BBC79481.1\|1042423_1042690_-	hypothetical protein	NA	NA	NA	NA
BBC79482.1\|1042760_1043261_-	heat-shock protein Hsp20	A0A222YXB4	Synechococcus_phage	1.2e-12	35.4
BBC79483.1\|1043372_1043489_+	conserved hypothetical protein	NA	NA	NA	NA
BBC79484.1\|1043485_1043728_+	peptide deformylase	NA	NA	NA	NA
BBC79485.1\|1043691_1044051_+	peptide deformylase	E3SLL2	Synechococcus_phage	1.4e-15	41.0
BBC79486.1\|1044071_1045004_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.2e-05	31.4

DBSCAN-SWA_3

1417360 : 1525002

112

Enterobacteria_phage(25.0%)

integrase,tRNA,protease,transposase

attL 1516556:1516570|attR 1530003:1530017

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBC79940.1\|1417360_1417696_-\|tRNA	tryptophanyl-tRNA synthetase	NA	NA	NA	NA
BBC79941.1\|1417885_1418746_+	squalene synthase HpnC	NA	NA	NA	NA
BBC79942.1\|1418819_1419710_+	squalene synthase HpnD	NA	NA	NA	NA
BBC79943.1\|1419735_1421034_+	amine oxidase/FAD-dependent phytoene desaturase	NA	NA	NA	NA
BBC79944.1\|1421091_1423062_+	squalene-hopene cyclase	NA	NA	NA	NA
BBC79945.1\|1423065_1423770_+	5'-methylthioadenosine nucleosidase	NA	NA	NA	NA
BBC79946.1\|1423907_1424042_-	hypothetical protein RSOLAG22IIIB_11094	NA	NA	NA	NA
BBC79947.1\|1424128_1425727_+	flavin monoamine oxidase	NA	NA	NA	NA
BBC79948.1\|1425726_1426161_+	alcohol dehydrogenase	NA	NA	NA	NA
BBC79949.1\|1426162_1426675_+	endoribonuclease L-PSP	NA	NA	NA	NA
BBC79950.1\|1426738_1426855_+	hypothetical protein	NA	NA	NA	NA
BBC79951.1\|1426863_1426986_-	hypothetical protein	NA	NA	NA	NA
BBC79952.1\|1427078_1428551_-	secretion protein	NA	NA	NA	NA
BBC79953.1\|1428616_1429474_-	membrane protein	NA	NA	NA	NA
BBC79954.1\|1429537_1429651_-	DUF1656 domain-containing protein	NA	NA	NA	NA
BBC79955.1\|1429771_1430269_-	MarR family transcriptional regulator	NA	NA	NA	NA
BBC79956.1\|1430416_1430842_-	hypothetical protein	NA	NA	NA	NA
BBC79957.1\|1430881_1431184_-	putative membrane protein	NA	NA	NA	NA
BBC79958.1\|1431254_1432376_+	spermidine/putrescine ABC transporter ATP-binding protein	NA	NA	NA	NA
BBC79959.1\|1432421_1433492_+	spermidine/putrescine ABC transporter substrate-binding protein	NA	NA	NA	NA
BBC79960.1\|1433547_1433955_+	spermidine/putrescine transporter permease protein	NA	NA	NA	NA
BBC79961.1\|1433983_1434445_+	UPF0260 protein	NA	NA	NA	NA
BBC79962.1\|1434545_1435247_+\|protease	putative zinc metalloprotease	NA	NA	NA	NA
BBC79963.1\|1435204_1435336_+	ser/threonine protein phosphatase	NA	NA	NA	NA
BBC79964.1\|1435692_1437153_+\|integrase	integrase	NA	NA	NA	NA
BBC79965.1\|1437241_1438375_+	phosphohydrolase	NA	NA	NA	NA
BBC79966.1\|1438377_1438776_+	predicted NTPase	NA	NA	NA	NA
BBC79967.1\|1439363_1439909_+	hybrid sensor histidine kinase/response regulator	NA	NA	NA	NA
BBC79968.1\|1440181_1440448_+	glutamate receptor 2.8-like	NA	NA	NA	NA
BBC79969.1\|1440528_1441101_-	resolvase	G8I4U3	Mycobacterium_phage	1.2e-24	37.2
BBC79970.1\|1442076_1442343_-	pyruvate dehydrogenase	NA	NA	NA	NA
BBC79971.1\|1442594_1442771_+	hypothetical protein	NA	NA	NA	NA
BBC79972.1\|1442847_1444275_+	conserved protein of unknown function	NA	NA	NA	NA
BBC79973.1\|1444605_1444806_-	chemotaxis protein	NA	NA	NA	NA
BBC79974.1\|1445380_1445524_+	MHC class I antigen ZJA transcript variant 3	NA	NA	NA	NA
BBC79975.1\|1445935_1446049_+	hypothetical protein	NA	NA	NA	NA
BBC79976.1\|1446950_1447352_+	CopG family transcriptional regulator	NA	NA	NA	NA
BBC79977.1\|1447348_1449109_+	hypothetical protein	NA	NA	NA	NA
BBC79978.1\|1449395_1450025_+	DNA recombinase/resolvase	A0A286S1P7	Klebsiella_phage	4.6e-25	38.7
BBC79979.1\|1450248_1451877_+\|integrase	phage integrase	A0A0E3Y5J2	Fusobacterium_phage	1.5e-06	27.0
BBC79980.1\|1453234_1453585_+\|transposase	transposase	NA	NA	NA	NA
BBC79981.1\|1453575_1453716_-	hypothetical protein	NA	NA	NA	NA
BBC79982.1\|1453759_1454908_+	pleiotropic regulatory protein DnrJ/EryC1/StrS	NA	NA	NA	NA
BBC79983.1\|1455033_1456245_+	hypothetical protein Absy_008_149	NA	NA	NA	NA
BBC79984.1\|1456414_1457485_+	oxidoreductase	NA	NA	NA	NA
BBC79985.1\|1457487_1458642_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
BBC79986.1\|1458742_1459828_+	methyltransferase	NA	NA	NA	NA
BBC79987.1\|1459819_1459942_-	DNA recombinase/resolvase	NA	NA	NA	NA
BBC79988.1\|1460254_1460557_+	transcriptional regulator XRE	NA	NA	NA	NA
BBC79989.1\|1460891_1461125_+	bacterial mobilization protein	NA	NA	NA	NA
BBC79990.1\|1461143_1462958_+	hypothetical protein Abor_003_090	NA	NA	NA	NA
BBC79991.1\|1463210_1463510_+\|integrase	integrase, partial	NA	NA	NA	NA
BBC79992.1\|1463472_1463808_+\|transposase	transposase	Q9ETV7	Enterobacteria_phage	8.1e-21	50.0
BBC79993.1\|1463804_1464710_+\|transposase	transposase	Q8W6R2	Burkholderia_virus	1.3e-94	61.1
BBC79994.1\|1464903_1465923_+\|integrase	integrase	NA	NA	NA	NA
BBC79995.1\|1465994_1466675_-	major pilin protein fimA	NA	NA	NA	NA
BBC79996.1\|1466704_1469164_-	TonB-dependent receptor	NA	NA	NA	NA
BBC79997.1\|1469518_1469947_+	endoribonuclease	NA	NA	NA	NA
BBC79998.1\|1469981_1471367_+	nucleobase cation symporter-1 (NCS1) family/cytosine/purines uracil thiamine allantoin permease	NA	NA	NA	NA
BBC79999.1\|1471373_1472519_+	acetylornithine deacetylase	NA	NA	NA	NA
BBC80000.1\|1472534_1473464_-	LysR family transcriptional regulator	NA	NA	NA	NA
BBC80001.1\|1473685_1474924_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
BBC80002.1\|1474976_1475165_+	cyclin-F	NA	NA	NA	NA
BBC80003.1\|1475614_1475950_+\|transposase	transposase	Q9ETV7	Enterobacteria_phage	8.1e-21	50.0
BBC80004.1\|1475946_1476852_+\|transposase	transposase	Q8W6R2	Burkholderia_virus	1.3e-94	61.1
BBC80005.1\|1477127_1477394_+	branched-chain amino acid transport	NA	NA	NA	NA
BBC80006.1\|1478313_1478547_-	transcriptional regulator LysR	NA	NA	NA	NA
BBC80007.1\|1479473_1479752_+	hypothetical protein	NA	NA	NA	NA
BBC80008.1\|1480491_1480608_-\|transposase	transposase	NA	NA	NA	NA
BBC80009.1\|1480647_1482060_-	amidohydrolase	NA	NA	NA	NA
BBC80010.1\|1482250_1484737_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	1.4e-13	33.0
BBC80011.1\|1484767_1485700_+	ABC transporter amino acid permease	NA	NA	NA	NA
BBC80012.1\|1485696_1486530_+	ABC transporter polar amino acid permease inner membrane subunit	NA	NA	NA	NA
BBC80013.1\|1486526_1487282_+	arginine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-25	38.1
BBC80014.1\|1487309_1488623_+	nitrilotriacetate monooxygenase	NA	NA	NA	NA
BBC80015.1\|1488634_1489981_+	hypothetical protein	NA	NA	NA	NA
BBC80016.1\|1490725_1490863_-	DNA polymerase beta subunit	NA	NA	NA	NA
BBC80017.1\|1491199_1491334_-\|transposase	IS5 family transposase	NA	NA	NA	NA
BBC80018.1\|1492136_1492274_+	hypothetical protein	NA	NA	NA	NA
BBC80019.1\|1492572_1493715_+	alpha-hydroxy-acid oxidizing enzyme	NA	NA	NA	NA
BBC80020.1\|1493959_1495366_+	porin B carbohydrate-selective OprB	NA	NA	NA	NA
BBC80021.1\|1495400_1497023_+	L-lactate permease	NA	NA	NA	NA
BBC80022.1\|1497191_1497533_-	DUF4440 domain-containing protein	NA	NA	NA	NA
BBC80023.1\|1497615_1498650_-	oxidoreductase	NA	NA	NA	NA
BBC80024.1\|1498671_1499961_-	sodium:dicarboxylate symporter/C4-dicarboxylate transporter	NA	NA	NA	NA
BBC80025.1\|1500027_1501440_-	TonB-dependent receptor	NA	NA	NA	NA
BBC80026.1\|1501400_1502351_-	TonB-dependent receptor	NA	NA	NA	NA
BBC80027.1\|1502509_1502650_-	hypothetical protein	NA	NA	NA	NA
BBC80028.1\|1502821_1503724_+	LysR family transcriptional regulator	NA	NA	NA	NA
BBC80029.1\|1503753_1504329_-	amidase	NA	NA	NA	NA
BBC80030.1\|1504331_1505120_-	amidase	NA	NA	NA	NA
BBC80031.1\|1505116_1505365_-	DUF4089 domain-containing protein	NA	NA	NA	NA
BBC80032.1\|1505339_1506566_-	aminotransferase V	NA	NA	NA	NA
BBC80033.1\|1506562_1507816_-	amidohydrolase/N-carbamyl-L-amino acid amidohydrolase	NA	NA	NA	NA
BBC80034.1\|1507964_1508087_-	GH3 auxin-responsive promoter	NA	NA	NA	NA
BBC80035.1\|1508126_1508273_-	hypothetical protein	NA	NA	NA	NA
BBC80036.1\|1508345_1508837_+	oxalate/formate MFS antiporter	NA	NA	NA	NA
BBC80037.1\|1508833_1509562_+	oxalate/formate MFS antiporter	NA	NA	NA	NA
BBC80038.1\|1509554_1510511_+	bile acid:sodium symporter	NA	NA	NA	NA
BBC80039.1\|1510510_1511887_+	gamma-glutamyltransferase	NA	NA	NA	NA
BBC80040.1\|1511901_1512102_+	gamma-glutamyltransferase	NA	NA	NA	NA
BBC80041.1\|1512104_1513343_+	porin O/P phosphate-selective	NA	NA	NA	NA
BBC80042.1\|1513821_1514727_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	3.0e-94	60.7
BBC80043.1\|1514723_1515059_-\|transposase	transposase	Q6H9S4	Enterobacteria_phage	2.8e-21	50.9
BBC80044.1\|1515451_1517137_-	secretion system type I outer membrane efflux pump lipoprotein NodT	NA	NA	NA	NA
1516556:1516570	attL	NA	NA	NA	NA
BBC80045.1\|1517133_1518333_-	multidrug transporter	NA	NA	NA	NA
BBC80046.1\|1518332_1521536_-	RND transporter	S5VTK5	Leptospira_phage	1.8e-56	22.3
BBC80047.1\|1522239_1522971_+\|integrase	integrase, partial	NA	NA	NA	NA
BBC80048.1\|1523389_1523656_+	exported protein of unknown function	NA	NA	NA	NA
BBC80049.1\|1523758_1524214_-	DUF2846 domain-containing protein	NA	NA	NA	NA
BBC80050.1\|1524345_1524465_+\|transposase	transposase	NA	NA	NA	NA
BBC80051.1\|1524837_1525002_+\|transposase	transposase	NA	NA	NA	NA
1530003:1530017	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1680921 : 1768442

106

Escherichia_phage(12.5%)

tail,capsid,protease,head,integrase,tRNA,plate

attL 1678846:1678861|attR 1728074:1728089

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1678846:1678861	attL	NA	NA	NA	NA
BBC80208.1\|1680921_1681068_+\|tRNA	tRNA-specific adenosine deaminase	NA	NA	NA	NA
BBC80209.1\|1681132_1681264_+	hypothetical protein Abor_033_013	NA	NA	NA	NA
BBC80210.1\|1681381_1681858_+	glutamine amidotransferase	NA	NA	NA	NA
BBC80211.1\|1681854_1682109_+	glutamine amidotransferase	NA	NA	NA	NA
BBC80212.1\|1682105_1682873_+	pseudouridine synthase	NA	NA	NA	NA
BBC80213.1\|1682876_1683500_+	methyltransferase	NA	NA	NA	NA
BBC80214.1\|1683545_1683659_+	hypothetical protein	NA	NA	NA	NA
BBC80215.1\|1683776_1684370_+	single-stranded DNA-binding protein	A0A0U2C0X4	Paracoccus_phage	2.0e-38	60.6
BBC80216.1\|1684522_1685818_+	polymerase	NA	NA	NA	NA
BBC80217.1\|1685868_1685985_-	hypothetical protein	NA	NA	NA	NA
BBC80218.1\|1686016_1686436_+	transcriptional regulator/DnaK suppressor protein	NA	NA	NA	NA
BBC80219.1\|1686515_1686779_+	site-specific recombinase	NA	NA	NA	NA
BBC80220.1\|1686832_1687189_-	hypothetical protein	NA	NA	NA	NA
BBC80221.1\|1687181_1688114_-\|tail	tail fiber protein	A0A077KC23	Edwardsiella_phage	3.8e-12	41.6
BBC80222.1\|1688268_1688424_-	hypothetical protein	NA	NA	NA	NA
BBC80223.1\|1688430_1688547_-	rare lipoprotein A	NA	NA	NA	NA
BBC80224.1\|1688497_1688800_-	hyaluronidase-1-like	NA	NA	NA	NA
BBC80225.1\|1688869_1690102_-\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	2.3e-65	38.1
BBC80226.1\|1690224_1691682_-\|protease	protease TldD	NA	NA	NA	NA
BBC80227.1\|1691872_1694137_+	trehalase	NA	NA	NA	NA
BBC80228.1\|1694126_1694240_+	hypothetical protein	NA	NA	NA	NA
BBC80229.1\|1694286_1694403_-	hypothetical protein	NA	NA	NA	NA
BBC80230.1\|1694674_1695346_-	phosphoglycerate mutase	NA	NA	NA	NA
BBC80231.1\|1695362_1697522_-	GMP reductase	NA	NA	NA	NA
BBC80232.1\|1697697_1698756_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	6.6e-93	51.0
BBC80233.1\|1698752_1699646_+	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	2.8e-84	53.3
BBC80234.1\|1699648_1700266_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A218MN57	uncultured_virus	1.1e-36	44.1
BBC80235.1\|1700258_1701185_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
BBC80236.1\|1701450_1701603_-	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
BBC80237.1\|1701637_1702447_+	DNA translocase FtsK	NA	NA	NA	NA
BBC80238.1\|1702554_1704192_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	6.4e-79	45.2
BBC80239.1\|1704188_1704884_+	RNA pseudouridine synthase	NA	NA	NA	NA
BBC80240.1\|1704929_1706093_-	glycosyl/hexosyl transferase	NA	NA	NA	NA
BBC80241.1\|1706319_1707006_-	glutathione S-transferase	NA	NA	NA	NA
BBC80242.1\|1707020_1708103_-\|tRNA	tRNA(5-methylaminomethyl-2-thiouridine)- methyltransferase	NA	NA	NA	NA
BBC80243.1\|1708135_1708450_-	(2Fe-2S) ferredoxin	NA	NA	NA	NA
BBC80244.1\|1708494_1709679_-	cysteine desulfurase	H7BUW1	unidentified_phage	3.9e-25	36.0
BBC80245.1\|1709709_1710855_-	cysteine desulfurase	NA	NA	NA	NA
BBC80246.1\|1710964_1711321_+	MFS transporter	NA	NA	NA	NA
BBC80247.1\|1711313_1711979_+	alpha/beta hydrolase	NA	NA	NA	NA
BBC80248.1\|1712186_1712963_-\|tRNA	tRNA/rRNA methyltransferase SpoU	NA	NA	NA	NA
BBC80249.1\|1712959_1714306_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	2.0e-41	32.9
BBC80250.1\|1714321_1714438_+	ATP-dependent DNA helicase SRS2 isoform X1	NA	NA	NA	NA
BBC80251.1\|1714628_1715942_+\|integrase	integrase	NA	NA	NA	NA
BBC80252.1\|1716533_1716770_+	disease resistance protein RGA2-like	NA	NA	NA	NA
BBC80253.1\|1717434_1717671_+	hypothetical protein	NA	NA	NA	NA
BBC80254.1\|1717722_1718091_-	hypothetical protein	NA	NA	NA	NA
BBC80255.1\|1718090_1718261_-	hypothetical protein OMM_03946	NA	NA	NA	NA
BBC80256.1\|1719160_1719601_-	hypothetical protein	NA	NA	NA	NA
BBC80257.1\|1719993_1720905_-	hypothetical protein	NA	NA	NA	NA
BBC80258.1\|1721026_1721374_-	hypothetical protein	NA	NA	NA	NA
BBC80259.1\|1721387_1722920_-\|tail	tail fiber protein	A0A291AUN5	Sinorhizobium_phage	1.2e-07	55.7
BBC80260.1\|1722983_1723535_-\|tail	bacteriophage tail protein	NA	NA	NA	NA
BBC80261.1\|1723545_1724640_-\|plate	baseplate J family protein	NA	NA	NA	NA
BBC80262.1\|1724644_1725421_-\|head	peptidase U35 phage prohead HK97	NA	NA	NA	NA
BBC80263.1\|1725420_1726641_-\|capsid	phage major capsid protein HK97	A0A0U4IJ43	Pseudomonas_phage	8.3e-15	22.7
BBC80264.1\|1727056_1729213_-\|tail	phage tail tape measure protein	NA	NA	NA	NA
1728074:1728089	attR	NA	NA	NA	NA
BBC80265.1\|1729214_1729343_+	hypothetical protein	NA	NA	NA	NA
BBC80266.1\|1729329_1729527_+	cytochrome oxidase subunit I, partial	NA	NA	NA	NA
BBC80267.1\|1729727_1730318_+	group I intron endonuclease	NA	NA	NA	NA
BBC80268.1\|1730412_1732233_-	Terminase	Q7Y413	Yersinia_phage	2.2e-40	27.1
BBC80269.1\|1732213_1732573_-	ATP synthase F0F1 subunit delta	NA	NA	NA	NA
BBC80270.1\|1732838_1733102_-	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
BBC80271.1\|1733098_1733941_-	hypothetical protein	NA	NA	NA	NA
BBC80272.1\|1734516_1734735_-	hypothetical protein Gaha_0122_018	NA	NA	NA	NA
BBC80273.1\|1735153_1735324_+	hypothetical protein	NA	NA	NA	NA
BBC80274.1\|1735292_1735616_-	hypothetical protein	NA	NA	NA	NA
BBC80275.1\|1735794_1736367_-\|plate	baseplate assembly protein	NA	NA	NA	NA
BBC80276.1\|1736376_1737507_-	Mu P family protein	NA	NA	NA	NA
BBC80277.1\|1737511_1738057_-	Mu-like prophage DNA circulation protein	NA	NA	NA	NA
BBC80278.1\|1738497_1739967_-\|capsid	major capsid protein	NA	NA	NA	NA
BBC80279.1\|1740054_1740420_-	hypothetical protein	NA	NA	NA	NA
BBC80280.1\|1740434_1741592_-\|tail	Mu-like protein prophage tail sheath protein gpL-like protein	NA	NA	NA	NA
BBC80281.1\|1741685_1741847_-	hypothetical protein	NA	NA	NA	NA
BBC80282.1\|1742242_1742647_-	HK97 gp10 family phage protein	NA	NA	NA	NA
BBC80283.1\|1742646_1742772_-	hypothetical protein	NA	NA	NA	NA
BBC80284.1\|1743028_1743580_-	membrane biogenesis protein AsmA	NA	NA	NA	NA
BBC80285.1\|1743688_1743841_-	DNA polymerase III subunit delta'	NA	NA	NA	NA
BBC80286.1\|1744246_1744555_-	membrane protein	NA	NA	NA	NA
BBC80287.1\|1744546_1744672_+	ATPase AAA-2 domain protein	NA	NA	NA	NA
BBC80288.1\|1744967_1745081_+	transcriptional regulator	NA	NA	NA	NA
BBC80289.1\|1745181_1745679_-	lysozyme	A0A088FRS5	Escherichia_phage	1.3e-27	45.8
BBC80290.1\|1745809_1745938_-	hypothetical protein	NA	NA	NA	NA
BBC80291.1\|1746082_1746382_-	pilus assembly protein PilM	NA	NA	NA	NA
BBC80292.1\|1746604_1746814_-	hypothetical protein	NA	NA	NA	NA
BBC80293.1\|1747085_1747958_-	E1-E2 ATPase family protein	NA	NA	NA	NA
BBC80294.1\|1748484_1748598_-	IncF plasmid conjugative transfer pilus assembly protein TraK	NA	NA	NA	NA
BBC80295.1\|1748676_1748796_+	hypothetical protein	NA	NA	NA	NA
BBC80296.1\|1749109_1749535_-	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, partial	NA	NA	NA	NA
BBC80297.1\|1749925_1750051_-	hypothetical protein	NA	NA	NA	NA
BBC80298.1\|1750206_1751562_-	folylpolyglutamate synthase	NA	NA	NA	NA
BBC80299.1\|1751570_1752386_-	acetyl-CoA carboxylase subunit beta	NA	NA	NA	NA
BBC80300.1\|1752515_1752644_+	hypothetical protein	NA	NA	NA	NA
BBC80301.1\|1752653_1752980_-	thiol reductase thioredoxin	A0A2I2L415	Orpheovirus	1.3e-12	41.5
BBC80302.1\|1752985_1753111_-\|tRNA	cysteine--tRNA ligase	NA	NA	NA	NA
BBC80303.1\|1753107_1756677_-	double-strand break repair helicase AddA	NA	NA	NA	NA
BBC80304.1\|1756673_1759850_-	nuclease	NA	NA	NA	NA
BBC80305.1\|1759846_1760308_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
BBC80306.1\|1760401_1760563_+	hypothetical protein	NA	NA	NA	NA
BBC80307.1\|1760870_1761557_+	two component transcriptional regulator CtrA	F4YXP8	Roseobacter_phage	3.6e-15	54.3
BBC80308.1\|1761567_1762377_-	hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	NA	NA	NA	NA
BBC80309.1\|1762376_1763735_-	phosphoglucosamine mutase	NA	NA	NA	NA
BBC80310.1\|1763807_1764908_-	dihydropteroate synthase	NA	NA	NA	NA
BBC80311.1\|1764979_1766884_-	cell division protein FtsH	C7U047	Ostreococcus_tauri_virus	3.2e-114	46.2
BBC80312.1\|1766921_1767041_-	filamentation induced by cAMP protein Fic	NA	NA	NA	NA
BBC80313.1\|1767107_1768442_-\|tRNA	Ile-tRNA lysidine synthase TilS	NA	NA	NA	NA

DBSCAN-SWA_5

2258549 : 2266092

Aeromonas_phage(33.33%)

plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBC80877.1\|2258549_2259206_+\|plate	baseplate assembly protein	Q2NPA1	Xanthomonas_phage	1.3e-30	43.9
BBC80878.1\|2259232_2261350_-	catalase HPII	A0A2K9L0T1	Tupanvirus	8.4e-140	49.3
BBC80879.1\|2261329_2261518_+	Sec23/Sec24 transport family protein	NA	NA	NA	NA
BBC80880.1\|2261525_2261885_+	Burkholderia phage Bcep781 gp51	H9C0X7	Aeromonas_phage	3.5e-14	42.9
BBC80881.1\|2261871_2263122_+	phage Mu protein	A0A2R3UAL9	Myoviridae_environmental_samples	4.6e-61	39.6
BBC80882.1\|2263121_2263697_+	Burkholderia phage Bcep781 gp32	H9C0Y0	Aeromonas_phage	5.8e-27	39.9
BBC80883.1\|2263808_2264222_+	hypothetical protein	NA	NA	NA	NA
BBC80884.1\|2264175_2264352_-	CASP-like protein 4A3	NA	NA	NA	NA
BBC80885.1\|2264376_2264808_+	hypothetical protein	NA	NA	NA	NA
BBC80886.1\|2264853_2266092_+	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	6.0e-29	36.6

DBSCAN-SWA_6

2623277 : 2654932

uncultured_Caudovirales_phage(14.29%)

tail,terminase,transposase,portal,integrase

attL 2619497:2619511|attR 2643688:2643702

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2619497:2619511	attL	NA	NA	NA	NA
BBC81241.1\|2623277_2624285_+\|integrase	integrase	A0A2H4JE37	uncultured_Caudovirales_phage	1.9e-49	34.9
BBC81242.1\|2625149_2625281_-	hypothetical protein	NA	NA	NA	NA
BBC81243.1\|2625792_2626152_-	hypothetical conserved protein	NA	NA	NA	NA
BBC81244.1\|2626327_2626675_-	F-box/kelch-repeat protein	NA	NA	NA	NA
BBC81245.1\|2626671_2627259_-	DNA polymerase III subunit epsilon	A0A1W6DWR2	Sphingobium_phage	2.4e-28	38.8
BBC81246.1\|2627255_2628053_-	phage recombination protein Bet	NA	NA	NA	NA
BBC81247.1\|2628054_2628516_-	hypothetical protein	NA	NA	NA	NA
BBC81248.1\|2628512_2628701_-	hypothetical protein	NA	NA	NA	NA
BBC81249.1\|2628700_2629021_-	chemotaxis protein	NA	NA	NA	NA
BBC81250.1\|2629180_2629390_-	hypothetical protein	NA	NA	NA	NA
BBC81251.1\|2629488_2629770_-	fusaric acid resistance protein	NA	NA	NA	NA
BBC81252.1\|2629769_2630636_-	polymer-forming cytoskeletal	NA	NA	NA	NA
BBC81253.1\|2630931_2631066_+	hypothetical protein	NA	NA	NA	NA
BBC81254.1\|2631081_2632020_-	hypothetical protein APO_0646	NA	NA	NA	NA
BBC81255.1\|2632722_2633436_-	phage-encoded protein-like protein	NA	NA	NA	NA
BBC81256.1\|2633439_2633631_+	copper-translocating P-type ATPase	NA	NA	NA	NA
BBC81257.1\|2633584_2634505_-	single-stranded DNA-binding protein	NA	NA	NA	NA
BBC81258.1\|2634529_2634823_+	single-stranded DNA-binding protein	A0A088FRR2	Escherichia_phage	5.4e-13	45.0
BBC81259.1\|2635316_2635517_+	hypothetical protein	NA	NA	NA	NA
BBC81260.1\|2635575_2635806_+	putative cro-like repressor	NA	NA	NA	NA
BBC81261.1\|2635841_2635964_-	glutaminase A	NA	NA	NA	NA
BBC81262.1\|2635964_2636225_+	hypothetical protein	NA	NA	NA	NA
BBC81263.1\|2636221_2636338_+	hypothetical protein	NA	NA	NA	NA
BBC81264.1\|2636463_2636580_+	hypothetical protein	NA	NA	NA	NA
BBC81265.1\|2636698_2636830_-	transcriptional regulator	NA	NA	NA	NA
BBC81266.1\|2637718_2639197_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.5e-34	27.8
BBC81267.1\|2639288_2639447_+	MFS transporter	NA	NA	NA	NA
BBC81268.1\|2640012_2640141_+	hypothetical protein	NA	NA	NA	NA
BBC81269.1\|2640137_2640254_+	serine hydrolase	NA	NA	NA	NA
BBC81270.1\|2640250_2640421_+	hypothetical protein Abor_031_056	NA	NA	NA	NA
BBC81271.1\|2640433_2640595_+	dihydroneopterin aldolase	NA	NA	NA	NA
BBC81272.1\|2640806_2641289_+	hypothetical protein	NA	NA	NA	NA
BBC81273.1\|2641880_2642444_+\|terminase	phage terminase small subunit	A0A076GD11	Sinorhizobium_phage	2.9e-07	31.7
BBC81274.1\|2642418_2643729_+\|terminase	terminase	A0A0N7IRE3	Acinetobacter_phage	1.2e-104	49.0
2643688:2643702	attR	NA	NA	NA	NA
BBC81275.1\|2643744_2645259_+\|portal	portal protein	NA	NA	NA	NA
BBC81276.1\|2645303_2645903_+	phage minor structual protein GP20	NA	NA	NA	NA
BBC81277.1\|2645982_2647341_+	phage protein	NA	NA	NA	NA
BBC81278.1\|2647340_2647589_+	DnaJ-class molecular chaperone CbpA	NA	NA	NA	NA
BBC81279.1\|2647552_2647957_+	hypothetical protein	NA	NA	NA	NA
BBC81280.1\|2647964_2648393_+	protein naked cuticle homolog 2	NA	NA	NA	NA
BBC81281.1\|2648417_2648537_-	hypothetical protein	NA	NA	NA	NA
BBC81282.1\|2648555_2648750_+	putative glutamine amidotransferasec	NA	NA	NA	NA
BBC81283.1\|2648749_2649421_+	putative phage protein	NA	NA	NA	NA
BBC81284.1\|2649422_2650322_+	putative phage protein	NA	NA	NA	NA
BBC81285.1\|2650323_2650530_+	carbohydrate esterase family 4 protein	NA	NA	NA	NA
BBC81286.1\|2650533_2652024_+\|tail	tail protein	B3GAJ6	uncultured_virus	7.9e-76	40.5
BBC81287.1\|2652079_2652511_+	phage protein	NA	NA	NA	NA
BBC81288.1\|2652507_2652855_+	putative phage protein	NA	NA	NA	NA
BBC81289.1\|2653044_2653566_+	putative phage-related protein	NA	NA	NA	NA
BBC81290.1\|2653570_2653870_-	hypothetical protein	NA	NA	NA	NA
BBC81291.1\|2653893_2654013_-	hypothetical protein	NA	NA	NA	NA
BBC81292.1\|2654107_2654932_+\|transposase	transposase (IS12528)	NA	NA	NA	NA

DBSCAN-SWA_7

2811614 : 2891923

Bacillus_phage(30.77%)

integrase,holin,transposase

attL 2832737:2832770|attR 2844870:2844885

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBC81467.1\|2811614_2812796_+\|integrase	integrase	A0A2H4JE37	uncultured_Caudovirales_phage	2.0e-29	28.1
BBC81468.1\|2814924_2815839_-	LysR family transcriptional regulator	NA	NA	NA	NA
BBC81469.1\|2815800_2815962_+	hypothetical protein	NA	NA	NA	NA
BBC81470.1\|2815985_2818319_+	TonB-dependent receptor	NA	NA	NA	NA
BBC81471.1\|2818360_2819611_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.8e-44	32.9
BBC81472.1\|2819674_2820811_+	carboxypeptidase G	NA	NA	NA	NA
BBC81473.1\|2821542_2822916_-\|integrase	integrase	A0A0U4JNS1	Bacillus_phage	3.0e-05	27.9
BBC81474.1\|2823275_2826251_+	DUF4062 domain-containing protein	NA	NA	NA	NA
BBC81475.1\|2826516_2826882_-	hypothetical protein Abin_012_003	NA	NA	NA	NA
BBC81476.1\|2827255_2828029_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	1.4e-92	65.9
BBC81477.1\|2828901_2830026_-\|integrase	integrase	A0A0U4JNS1	Bacillus_phage	8.5e-06	27.1
BBC81478.1\|2830032_2830275_-\|integrase	integrase, partial	NA	NA	NA	NA
BBC81479.1\|2830527_2832342_-	hypothetical protein Abor_003_090	NA	NA	NA	NA
BBC81480.1\|2832360_2832597_-	bacterial mobilization protein	NA	NA	NA	NA
2832737:2832770	attL	NA	NA	NA	NA
BBC81481.1\|2833388_2833967_+	von Willebrand factor type A	NA	NA	NA	NA
2832737:2832770	attL	NA	NA	NA	NA
BBC81482.1\|2834087_2834738_+	protein phosphatase 2C-like protein	NA	NA	NA	NA
BBC81483.1\|2834734_2836954_+	topoisomerase	NA	NA	NA	NA
BBC81484.1\|2837292_2838915_-\|integrase	phage integrase	A0A0E3Y5J2	Fusobacterium_phage	3.2e-06	28.1
BBC81485.1\|2839032_2839170_-	kallikrein-4	NA	NA	NA	NA
BBC81486.1\|2839459_2840170_+	hypothetical protein	NA	NA	NA	NA
BBC81487.1\|2840269_2841661_-\|integrase	integrase	A0A0U4JNS1	Bacillus_phage	4.3e-07	28.2
2840197:2840230	attR	NA	NA	NA	NA
BBC81488.1\|2842598_2842760_+	exodeoxyribonuclease VII large subunit	NA	NA	NA	NA
2840197:2840230	attR	NA	NA	NA	NA
BBC81489.1\|2843534_2844548_-\|integrase	integrase	A0A0U4JNS1	Bacillus_phage	7.6e-06	28.2
BBC81490.1\|2845335_2845632_-	peptidase S8/S53 subtilisin kexin sedolisin	NA	NA	NA	NA
BBC81491.1\|2846264_2846600_+\|transposase	transposase	Q6H9S4	Enterobacteria_phage	2.8e-21	50.9
BBC81492.1\|2846596_2847502_+\|transposase	transposase	Q8W6R2	Burkholderia_virus	1.3e-94	61.1
BBC81493.1\|2847641_2848814_+	conjugative relaxase domain protein	NA	NA	NA	NA
BBC81494.1\|2848826_2849696_-	tetratricopeptide repeat protein 25	NA	NA	NA	NA
BBC81495.1\|2849918_2850560_-	polyamine ABC transporter permease	NA	NA	NA	NA
BBC81496.1\|2850595_2851582_-	rho-associated protein kinase 1 isoform X2	NA	NA	NA	NA
BBC81497.1\|2851611_2852262_-	DUF4755 domain-containing protein	NA	NA	NA	NA
BBC81498.1\|2853457_2854057_+	DNA resolvase	A0A0A7NPV4	Enterobacteria_phage	2.2e-29	45.7
BBC81499.1\|2854917_2855883_-	nitrate/nitrite transporter ATP-binding protein NtrA	NA	NA	NA	NA
BBC81500.1\|2855879_2856464_-	two component transcriptional regulator	NA	NA	NA	NA
BBC81501.1\|2856478_2860357_-	molybdopterin oxidoreductase	NA	NA	NA	NA
BBC81502.1\|2860410_2863308_-	nitrite reductase	NA	NA	NA	NA
BBC81503.1\|2863326_2864970_-	hypothetical protein Abci_004_007	NA	NA	NA	NA
BBC81504.1\|2864969_2866151_-	MFS transporter	NA	NA	NA	NA
BBC81505.1\|2866989_2867463_+\|transposase	transposase	A0A2H4UV16	Bodo_saltans_virus	4.2e-07	33.8
BBC81506.1\|2868235_2869114_+	LysR family transcriptional regulator	NA	NA	NA	NA
BBC81507.1\|2870132_2870831_+	aspartate racemase	NA	NA	NA	NA
BBC81508.1\|2871252_2871393_+\|transposase	transposase	NA	NA	NA	NA
BBC81509.1\|2872661_2873654_-	transcriptional regulator	NA	NA	NA	NA
BBC81510.1\|2874935_2876069_-	major royal jelly protein	NA	NA	NA	NA
BBC81511.1\|2876070_2876505_-	cupin	NA	NA	NA	NA
BBC81512.1\|2876553_2877573_-	Zn-dependent oxidoreductase	NA	NA	NA	NA
BBC81513.1\|2877571_2877976_+	transcriptional regulator MarR/HxlR	NA	NA	NA	NA
BBC81514.1\|2878259_2878394_+	hypothetical protein	NA	NA	NA	NA
BBC81515.1\|2878368_2879160_-	membrane protein	NA	NA	NA	NA
BBC81516.1\|2879207_2880098_-	DNA polymerase III subunit epsilon	A0A223W0B0	Agrobacterium_phage	1.3e-28	33.6
BBC81517.1\|2880537_2881431_-	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
BBC81518.1\|2881467_2881782_-	QacE family quaternary ammonium compound efflux SMR transporter	NA	NA	NA	NA
BBC81519.1\|2881800_2882484_-	amino acid transporter	NA	NA	NA	NA
BBC81520.1\|2882502_2883408_+	LysR family transcriptional regulator	NA	NA	NA	NA
BBC81521.1\|2883445_2884411_-	AraC family transcriptional regulator	NA	NA	NA	NA
BBC81522.1\|2884430_2885942_-	acetyl-CoA hydrolase	NA	NA	NA	NA
BBC81523.1\|2886768_2886903_-\|transposase	IS5 family transposase	NA	NA	NA	NA
BBC81524.1\|2886940_2887060_+	MutS -like protein 5	NA	NA	NA	NA
BBC81525.1\|2887272_2889774_+	TonB-dependent receptor	NA	NA	NA	NA
BBC81526.1\|2889845_2891375_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
BBC81527.1\|2891386_2891923_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. AP018516

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. AP018515

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection