CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
AP018587	Staphylococcus caprae JMUB898 DNA, complete genome	6 crisprs	csa3,DEDDh,cas3,DinG	2	7	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: AP018587_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018587_2

451288-451377

Orphan

Consensus_repeat	Method
AGAATTTCTACAGATTAAAATCTTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of AP018587_2

>merge|AP018587|2|451288-451377|CRISPRCasFinder
AGAATTTCTACAGATTAAAATCTTAGTTGTTTAGAGGAATACAATAGACCAGGTCTATTGCATAAGAGTTTCTACAGATTAAAATCTTAG

>AP018587|2|1|451288-451377|CRISPRCasFinder
AGAATTTCTACAGATTAAAATCTTAG	TTGTTTAGAGGAATACAATAGACCAGGTCTATTGCATA
AGAGTTTCTACAGATTAAAATCTTAG

Protein	Signature genes	Signature genes Name	Protein_function
AP018587.1\|BBD94023.1\|458880_459372_+\|putative-glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
AP018587.1\|BBD94013.1\|449050_449593_-\|TetR-family-regulatory-protein	unknown	unknown	gnl\|CDD\|224228
AP018587.1\|BBD94014.1\|449723_450023_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226806
AP018587.1\|BBD94008.1\|445578_445752_+\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94025.1\|460868_461990_+\|glycosyltransferase,-group-2-family-protein	unknown	unknown	gnl\|CDD\|132997
AP018587.1\|BBD94007.1\|444565_445510_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|368185
AP018587.1\|BBD94012.1\|448331_449036_-\|putative-short-chain-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
AP018587.1\|BBD94016.1\|450890_451268_+\|putative-glyoxalase	unknown	unknown	gnl\|CDD\|226134
AP018587.1\|BBD94017.1\|451446_451677_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226677
AP018587.1\|BBD94018.1\|451896_452463_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274100
AP018587.1\|BBD94024.1\|459371_460862_+\|diapolycopene-oxygenase	unknown	unknown	gnl\|CDD\|224154
AP018587.1\|BBD94010.1\|446354_447191_-\|putative-hydrolase	unknown	unknown	gnl\|CDD\|223669
AP018587.1\|BBD94020.1\|454568_455627_+\|putative-regulatory-protein	unknown	unknown	gnl\|CDD\|226167
AP018587.1\|BBD94011.1\|447216_448221_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225070
AP018587.1\|BBD94026.1\|462027_462891_+\|squalene-desaturase	unknown	unknown	gnl\|CDD\|224478
AP018587.1\|BBD94015.1\|450035_450854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|187561
AP018587.1\|BBD94019.1\|452713_454111_+\|D-serine/D-alanine/glycine-transporter	unknown	unknown	gnl\|CDD\|224038
AP018587.1\|BBD94021.1\|456130_457537_+\|polyphosphate-kinase-2-family-protein	unknown	unknown	gnl\|CDD\|274736
AP018587.1\|BBD94009.1\|445699_446320_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379275
AP018587.1\|BBD94022.1\|457985_458690_+\|putative-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381594

Protein	Function_ID	Function_description	E-value
AP018587.1\|BBD94013.1\|449050_449593_-\|TetR-family-regulatory-protein	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.60515e-12
AP018587.1\|BBD94014.1\|449723_450023_+\|hypothetical-protein	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	4.37145e-30
AP018587.1\|BBD94025.1\|460868_461990_+\|glycosyltransferase,-group-2-family-protein	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	2.25146e-23
AP018587.1\|BBD94007.1\|444565_445510_-\|amidohydrolase-family-protein	gnl\|CDD\|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	8.74391e-21
AP018587.1\|BBD94012.1\|448331_449036_-\|putative-short-chain-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.17117e-70
AP018587.1\|BBD94016.1\|450890_451268_+\|putative-glyoxalase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	7.16781e-41
AP018587.1\|BBD94017.1\|451446_451677_-\|hypothetical-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	5.08635e-24
AP018587.1\|BBD94018.1\|451896_452463_-\|hypothetical-protein	gnl\|CDD\|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	3.11368e-09
AP018587.1\|BBD94024.1\|459371_460862_+\|diapolycopene-oxygenase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	8.9818e-109
AP018587.1\|BBD94010.1\|446354_447191_-\|putative-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.24836e-18
AP018587.1\|BBD94020.1\|454568_455627_+\|putative-regulatory-protein	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.78973e-104
AP018587.1\|BBD94011.1\|447216_448221_-\|hypothetical-protein	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	1.36655e-59
AP018587.1\|BBD94026.1\|462027_462891_+\|squalene-desaturase	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	2.8929e-81
AP018587.1\|BBD94015.1\|450035_450854_+\|hypothetical-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.53065e-79
AP018587.1\|BBD94019.1\|452713_454111_+\|D-serine/D-alanine/glycine-transporter	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
AP018587.1\|BBD94021.1\|456130_457537_+\|polyphosphate-kinase-2-family-protein	gnl\|CDD\|274736	TIGR03708, poly_P_AMP_trns, polyphosphate:AMP phosphotransferase. Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (PAP), which can transfer the terminal phosphate from poly(P) to AMP, yielding ADP. In the opposite direction, this enzyme can synthesize poly(P). Each domain of this protein family is homologous to polyphosphate kinase, an enzyme that can run in the forward direction to extend a polyphosphate chain with a new terminal phosphate from ATP, or in reverse to make ATP (or GTP) from ADP (or GDP). [Central intermediary metabolism, Phosphorus compounds].	1.58731e-138
AP018587.1\|BBD94009.1\|445699_446320_-\|hypothetical-protein	gnl\|CDD\|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.81293e-06
AP018587.1\|BBD94022.1\|457985_458690_+\|putative-transglycosylase-IsaA	gnl\|CDD\|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.6475e-05

>AP018587.1|BBD94016.1|450890_451268_+|putative-glyoxalase
MMHSMWFNLNVKDLDRSEQFFKTLGFEINKNPDMLDKMVGISIGQTIVILIENNHFESVSHQEVDAHPNEVMISLGVKENKEVDELVEKVESAGGTIIDPPGVKQGYYGAMFADPDGHKFNFLVC
>AP018587.1|BBD94015.1|450035_450854_+|hypothetical-protein
MTKSILVIGATGKQGNAVVKQLLEDGWHVRAFTRNKNNEKLTSIENEHLEIFEGDLSNEDSLAQAMQDQYGLYSVQPIIPDNVEEELRQGEMIIDTAERQGVNYVVYSTAGGVNRDRTGPHFEALAQLENKIKASRLNFTIIKPSFFMDNFLRITKVENGEIKIPEFINPNVKFAMISSIDIAKIASTLFEDAESYNHQELEIASDELTLNEVVKTFATVTGKPTEIEGAFSSGTAERSWLEEKGYVIDFVQMERINPTRLTLDKWIAEVDF
>AP018587.1|BBD94014.1|449723_450023_+|hypothetical-protein
MSLNKEQRRITAIELQEHFNESTLSMEDIANKMSISVEEVEKVLNMNAPNGFFGNQLQRFIHLVWDIRDVMNSNIKENGDTPEEYTYLKGEKEDYWFLQ
>AP018587.1|BBD94013.1|449050_449593_-|TetR-family-regulatory-protein
MRKDALENRQRIEEKAIELFKEHGVDTVSMNRISKELGIGMGTLYRHFKDKSDLCYHIIEHDFDEIIHQMKRVASTSQSKEEIMKQSLDVFLKFKFENSDLLNCIEESNTKTQFHHSQFFSDLFDFYYDLFHDGHDERWATFKTDMLLKSLSTKAYEIQRSKRQLSNNEIRDNLMRLYLN
>AP018587.1|BBD94012.1|448331_449036_-|putative-short-chain-oxidoreductase
MDRVTLITGGNKGLGYEAAKELKAKGYKVYIGSRNEERGQKASNELGVDYVQLDVSDDESVQQAFKTLSEKEGRVDVLINNAGISGGFAKVADITVEDVEKVYNTNVFGIVRMMNTFIPLLEQSQQPVVVNVSSGLGSFGMVTNPDKAESKVNSLAYCSSKSAVTMLTLQYSKGLPHMQINAADPGSTNTDLVGDFSNNSKPASEGVKPIVELATINADGPTGTFIDGDGPMPW
>AP018587.1|BBD94011.1|447216_448221_-|hypothetical-protein
MKSINFEEHYVVDDIQKETMKYMSSDPNGVPMQTMLKGLEQKSGFTNADDITKHDERIKFMDEHDVEMQVLSYGNGAPSNLEGERAIELCQQANDTLAKYVNEHPDRFVGFATLPINEPQAAVEEFKRCIKELGFKGALIMGHPKNGFLDQDQYDDLFATAEALNVPIYLHPSPVQSDVYQAYYKGNYSDVTAATFACFGYGWHVDVGIHAIHLVLSGVFDRHPNLNMIIGHWGEFVPFFLERMDDILFADHLEHPISYYFKNNFYITPSGMLTKPQFDLVKAEVGVDRILYSADYPYVEPDKLGTFLDELDLTEEEKEKISYKNGAKLLGLEK
>AP018587.1|BBD94010.1|446354_447191_-|putative-hydrolase
METLELHGAKLRYHKIGKGPVLILIPGANGTGDIYMPLAKQIQDHFTVVAVDRRGYGQSELTEPLPEEVSNPDSRYRVKRDAQDIAELAKSLSDEPVYVLGSSSGAIVAMHVLKEHPDVVKRIAFHEPPINTFLPNAKYWQDKNEEIIDIAVNEGMPQAMKLFGETLKTSQLDQQYMSKPAQSEDDAESKKRFEEMLGWFKYEIRQYTESDISIEDLNQHKDIITLLNGTDSKGSFPQEVNFFIKDETGIEIVDIPGGHLGYIQKPEGFAEVLLNIWN
>AP018587.1|BBD94009.1|445699_446320_-|hypothetical-protein
MLFERNKPYTNETLLDKENILELIQFERFCRDNALWDSMRSCFAEDSRVNISWFDGTGEEFVKSSEEMNRYAPHQIYNTQMWINDNRAIAMMQATIQFRVDIKNVEMQLDSDAKIIYSLEKNEEGIWLIKGLGSIYEKDKLTPVIPTTINLPNSDFEGYRKSYACLSYALNELGYDVNHDLPGIDRPEAVNKYYEQLDHWLTQNEE
>AP018587.1|BBD94008.1|445578_445752_+|hypothetical-protein
MALVLYRKEADAFLIITFNFVVSTIGIVKIIFLNDISVLLLILHFELTNDRAVRNIY
>AP018587.1|BBD94007.1|444565_445510_-|amidohydrolase-family-protein
MKKIDLHAHYISPGFSQFLDDYFDGKGDGVKTPPFSPESYINLMKEQDIEYGVLSISSPHISAAPDDKMLELAEEVNTYAADITQQYSDQIGFFATLPLPLAEESVNTIDKALDDQQALGFTLPTNARGVYLGDERLDPVLEKLNERQATVAIHPNEPKPAIKAMSEEVPPPLMEFIFDTTRTIIYMSQKNVFSKYPNIKWIVPHCGALLPVIAQRVAMGNKMFGSEKQPDDLEQVMKNLYFDLAGKVLPYQLPTLLEMVDPDKIVYGSDAPYTTNQVVSMLANEIESTDLITIDSKIHMLYDNGKALLDKMKY
>AP018587.1|BBD94017.1|451446_451677_-|hypothetical-protein
MKLLDRINQLANKEKVESLSIEEKQEQHQLRQEYLKMIRGQVLTTFSTMKVLDPLGQDVTPDKVYELRKEYGNIQE
>AP018587.1|BBD94018.1|451896_452463_-|hypothetical-protein
MDATKIDPRIIRTKKLLVNAFQKVSREKKLSQVSVKDITDEATVNRATFYAHFTDKYDILDYTLSVTILKDLNDTLNISEVINEEILSNIFISIAYYMVEVQDSCEMNSEEFCNQAHKRINNELEDIFTIMLENSFPSHEREILVNSASFLAAGVCGLAKHWLETSKLTPETFIKKNLPFLIQHITQL
>AP018587.1|BBD94019.1|452713_454111_+|D-serine/D-alanine/glycine-transporter
MADKLQRELSNRHIQLIAIGGAIGTGLFLGAGASIHLAGPSILLTYIIVGFILFMFMRAMGELLLSNLGFKSFGDIAHHHIGSMAGFMVGWTYWLTWIISGMAEVTAVAKYVDFWYPEMPNWITAAATILILVALNLFSAKLFGELEFWLSIIKVITIFALIIIGIVMIVFAMKTQYGPATVTNIWKEGGFFPNGASGFFMSFQMAIFSFIGIELIGITAGETKDPHTTIPQAINNVPFRILIFYIGSLAVIMSVVPWDKLNPDDSPYVKLFGLIGIPFAAGIINFVVLTAAASSCNSGIFANSRTMFGLAGRKQGPAFLHKTNKNGVPYYAILVTCGLLSISVILNAIFKDATKVFVQITTFSTVLNILIWAVIMVAYLGFLKHNPELHKESNYRMPGGKYMAYGILVFFAFIFVILLINSSTRLAVLSIPVWIGVLFLMYQKYKKESRKTEIPTETEEDVEEA
>AP018587.1|BBD94020.1|454568_455627_+|putative-regulatory-protein
MSAIRNIDGPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMQYHPIFKTLLGVVQAIQFTVPALIGALIAMKFNLTPLAIAVVASASYVGSGAAQFKNGAWVIAGIGDLINTMITAAIAVLLILLVEERVGSMALIVFPTIIGGLSATIGVFTLPYVRLITTGIGNMLNSFTELQPVLMSMLISMVFSFIIISPLSTVAIAMAIGLSGIAAGSASIGIAATEAVLLIGTSQVNRLGIPLSIFFGGVKMMMPNMVKYPVIMVPIFITAALSGIASGMIGIGGTKESAGFGFIGMVGPINAFKFMHVDSPWLSVLLIVVAFFVVPFLVAWILDLLLRKVIRLYSNDIFKFMG
>AP018587.1|BBD94021.1|456130_457537_+|polyphosphate-kinase-2-family-protein
MSYNIEALQLKVAQLSRKTHELGIPVMILFEGVPASGKTRLSNELLLNLDAKYTDFIATKSPEAHNLRYQFLQKYWNTLPQKGNINIYFRSWYSHYLDYKENQIKQNQYSNYDVLIRQIDDFENMLKKDNYEIIKFFIEINEEKRQEHIEQTKENPLMKWKVQEYEKVIPQDIYISEMRQIINDSDDWKVIDYTERKQAIENMYLHIIERLESAIDNFQTHESVIDGNFNKNFSTSLFDIEVPKIHKKEYKDQMEILQNRMRELQFALYERKIPLVLVFEGMDAAGKGGNIKRIREKLDPTGYQVHGISAPTDVEKNHHYLWRFAKEMPKSGHVEIFDRSWYGRVLVERVEGFAEQAEWKRAYKEINQFEQMWTDEGALIIKFFLCLDKKEQLKRFKDREKNPDKQWKITHEDWRNREKWDLYLEASYDMIKHTNMNEAPWHVIPADHKKTSRIKVLQTIINRCEEVL
>AP018587.1|BBD94022.1|457985_458690_+|putative-transglycosylase-IsaA
MKKTVISTSLALSLGVAGFALTGHEAHASEATNVDQAHLADLAQNHPDQLNAKPVQAGAYDIHFVNNGFEYNFTSNGTNWSWSYQAAGSQSSSADYTQSYNQESSNQSVSSNTQSSNTNVEAVSAPTTSHHNYSTSTTSYSAPSSSSASTGGSVKAQFLAAGGTEAAWNAIVMPESGGNPNAVNPAGYRGLGQTMESWGTGSVASQTKGMINYANSRYGSLSNAIDFRASHGWW
>AP018587.1|BBD94023.1|458880_459372_+|putative-glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MMKNIKKLAQLVILHSVFWFSVQMSIAQLGTRIPLRFFDKNAHFFRPFQWEKGGQIWGDTLQISKWKKLIPEGTKLNSAIYDKSDLTNNIEETRHLLLEMRRAELVHWLSMVPLIVFIKTSKYIKYINLLYVVFSHVPIIIVQRYNRPRIERFIRLVEKRGKK
>AP018587.1|BBD94024.1|459371_460862_+|diapolycopene-oxygenase
MTKSVIVIGGGLGGIAAAIRMAQSGFNVKLFEQNNHIGGKVNRLDESGFGFDLGPSILTMPYIFEKLFNYSDKKMSDYVEIERLPLQWRNFFSNGETIDLYENNEATVLNNVQLNEKDKAELDRYFKYTERIYRFTEKGYFNHGLDTLPEILKYHGPLKALHGFDYFSTMQQAIHRYISNPRLREILGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVKGGIHHLAQALEQLAIEEGVELHTGTSVNNIKTYHHNVTGVRLANGDIVEADYIISNMEVIPTYKYLLHFSQQKIDQLEKTYEPASSGYVMHLGVNRSYPQLAHHNFFFSNDSKRNYDEVFHQKVLPQDPTIYLVNSNKTDLQQAPDEFENIKVLPHIPYIQDKPFKKEDYEAFKTRVLTKLEKMGLTDLRKHMIYEDMWTPEDIRQHYHSHRGAIYGVVADKKKNKGFKFPKHSKYFDNLFFVGGSVNPGGGMPMVTLSGLQVADKINAIEAQKE
>AP018587.1|BBD94025.1|460868_461990_+|glycosyltransferase,-group-2-family-protein
MKMIQFILTILSTISLICGRLIFNQRHRLLSSQSPIIHSNEVTIIIPARNEERRLPHLLQSLQGQQGIYEVIVMDDGSKDNTKEIAQTFGATVYETEQNFDRQWFGKSHACYQGATNAQSELLMFVDADVTFGHPHAIEKILNTYRKQHNHGLLSVQPFHETGKFYESLSAIFNLMTVVGVNQFSSLARQSNNDIAFGPITLMHRDDYFKTDGHKNAQHSIIEGFALGEKFESVQLPVTVYEGGNDVKFRMYEDGIQSLIQGWTKHFSVGANKTQPQIMLAIVMWLMGSITSTLTLLISVFTKPASRIVSYLFYVLYTCQFVRLHRRVGAFSMVLLILHPVLFIFFIFIFANSWRHTHFSKKVEWKGRSFKIN
>AP018587.1|BBD94026.1|462027_462891_+|squalene-desaturase
MTTNEENFKYCHQIMKEHSKSFSYAFDFLPEQERQAVWVIYAVCRIIDDSIDVHENPQILKDIHEDISYIENTIDISHHEFKSNQSIMVALYVVSQHYTIEYQSFYNLIQSVYEDQNFEMFETDEALLNYCYGVAGTVGEVLTPVLAQSPNKETYATARKLGEALQITNILRDVGEDFENGRIYFSESSLARFDVSIENEFNHRISNQYIDLWEYFAAIAEDDYEIALSNIDTFNKEAQPIIELAAVIYRAILDEVRKASYTLHRRVYVSKLNKAKLYRKIKNKYQL

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Crispr_ID: AP018587_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018587_3

469706-469848

Orphan

Consensus_repeat	Method
TTTCTTGAGGAAATCCTCTGTGTTGGGGCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of AP018587_3

>merge|AP018587|3|469706-469848|CRISPRCasFinder
TCTTATGAGGAACCCCTTGTTGTTAGGGCCCCAACTTGCATTGCCCGTAGGATTTCTTGAGGAAATCCTCTGTGTTGGGGCCCCGACCCCAACTTGCATTGCTTGTAGGGTTTCTTGAGGAAATCCTTTGTGTTGGGGCCCCG

>AP018587|3|2|469706-469848|CRISPRCasFinder
TCTTATGAGGAACCCCTTGTTGTTAGGGCCCCA	ACTTGCATTGCCCGTAGGATTTCTTGAGGAAATCCTCTGTGTTGGGGCCCCGACCCCAACTTGCATTGCTTGTAGGG
TTTCTTGAGGAAATCCTTTGTGTTGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
AP018587.1\|BBD94037.1\|474148_475090_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187566
AP018587.1\|BBD94034.1\|469907_470777_+\|dehydrogenase	unknown	unknown	gnl\|CDD\|187613
AP018587.1\|BBD94033.1\|469207_469603_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371476
AP018587.1\|BBD94025.1\|460868_461990_+\|glycosyltransferase,-group-2-family-protein	unknown	unknown	gnl\|CDD\|132997
AP018587.1\|BBD94028.1\|464632_465793_+\|N-succinyldiaminopimelate-aminotransferase	unknown	unknown	gnl\|CDD\|181219
AP018587.1\|BBD94038.1\|475285_476011_-\|intercellular-adhesion-protein-C	unknown	unknown	gnl\|CDD\|226446
AP018587.1\|BBD94042.1\|479084_479312_+\|FeoA-family-protein	unknown	unknown	gnl\|CDD\|377199
AP018587.1\|BBD94041.1\|478319_478871_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|274100
AP018587.1\|BBD94031.1\|468618_468777_+\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94030.1\|466166_468554_-\|copper-exporting-P-type-ATPase-A	unknown	unknown	gnl\|CDD\|319783
AP018587.1\|BBD94043.1\|479317_481312_+\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
AP018587.1\|BBD94032.1\|468823_469030_-\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94024.1\|459371_460862_+\|diapolycopene-oxygenase	unknown	unknown	gnl\|CDD\|224154
AP018587.1\|BBD94026.1\|462027_462891_+\|squalene-desaturase	unknown	unknown	gnl\|CDD\|224478
AP018587.1\|BBD94035.1\|470865_471426_+\|putative-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
AP018587.1\|BBD94027.1\|462903_464409_+\|4,4'-diapophytoene-desaturase	unknown	unknown	gnl\|CDD\|274273
AP018587.1\|BBD94040.1\|476674_478219_+\|1-pyrroline-5-carboxylate-dehydrogenase	unknown	unknown	gnl\|CDD\|179543
AP018587.1\|BBD94036.1\|471589_474097_+\|TarF-like-protein	unknown	unknown	gnl\|CDD\|367953
AP018587.1\|BBD94039.1\|476159_476345_+\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94029.1\|465870_466077_-\|mercuric-ion-binding-protein	unknown	unknown	gnl\|CDD\|225328

Protein	Function_ID	Function_description	E-value
AP018587.1\|BBD94037.1\|474148_475090_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.42132e-115
AP018587.1\|BBD94034.1\|469907_470777_+\|dehydrogenase	gnl\|CDD\|187613	cd05355, SDR_c1, classical (c) SDR, subgroup 1. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.93392e-145
AP018587.1\|BBD94033.1\|469207_469603_-\|hypothetical-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	5.22855e-06
AP018587.1\|BBD94025.1\|460868_461990_+\|glycosyltransferase,-group-2-family-protein	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	2.25146e-23
AP018587.1\|BBD94028.1\|464632_465793_+\|N-succinyldiaminopimelate-aminotransferase	gnl\|CDD\|181219	PRK08068, PRK08068, transaminase; Reviewed.	5.1567e-142
AP018587.1\|BBD94038.1\|475285_476011_-\|intercellular-adhesion-protein-C	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	1.13829e-14
AP018587.1\|BBD94041.1\|478319_478871_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	7.92127e-09
AP018587.1\|BBD94030.1\|466166_468554_-\|copper-exporting-P-type-ATPase-A	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
AP018587.1\|BBD94043.1\|479317_481312_+\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
AP018587.1\|BBD94024.1\|459371_460862_+\|diapolycopene-oxygenase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	8.9818e-109
AP018587.1\|BBD94026.1\|462027_462891_+\|squalene-desaturase	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	2.8929e-81
AP018587.1\|BBD94029.1\|465870_466077_-\|mercuric-ion-binding-protein	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	1.01831e-16
AP018587.1\|BBD94027.1\|462903_464409_+\|4,4'-diapophytoene-desaturase	gnl\|CDD\|274273	TIGR02734, Phytoene_desaturase_lycopene-forming, phytoene desaturase. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	5.2836e-134
AP018587.1\|BBD94042.1\|479084_479312_+\|FeoA-family-protein	gnl\|CDD\|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	2.28642e-12
AP018587.1\|BBD94036.1\|471589_474097_+\|TarF-like-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	2.49096e-83
AP018587.1\|BBD94040.1\|476674_478219_+\|1-pyrroline-5-carboxylate-dehydrogenase	gnl\|CDD\|179543	PRK03137, PRK03137, 1-pyrroline-5-carboxylate dehydrogenase; Provisional.	0
AP018587.1\|BBD94035.1\|470865_471426_+\|putative-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	7.57786e-97

>AP018587.1|BBD94033.1|469207_469603_-|hypothetical-protein
MQKKYIIITIIIIIFVGPGLIFNIGKYIYFNYQSHEEAKTKAKVHRLLKQKGWEDKIKTEKPNFTLNTRENNVEVTFKDEPYNTYQYDVNDDGKVTGDAELKMKYKERFDNDKKYREYRKRHRFEEKYDLK
>AP018587.1|BBD94032.1|468823_469030_-|hypothetical-protein
MKTLLKGVISVLIILGIIKTFQDHDILNEAGHYYEQAKSGEIVQDFSNFNFNNFKDLDLENLKPSDFF
>AP018587.1|BBD94031.1|468618_468777_+|hypothetical-protein
MFNNIENKNTYVIDKDYARVIAFIFKKLSEQSKDQACEMEKLLNVYLLVLKI
>AP018587.1|BBD94030.1|466166_468554_-|copper-exporting-P-type-ATPase-A
MTHKTTTLDITGMTCAACSNRIEKKLNRLDDVSAQVNLTTEKATIEYDADQYDSKSFISEIQKLGYDVRTEKQELDITGMTCAACSNRIEKVLNKTEGIQHATVNLTTEQALVSYYPNAINTDRIIQRIQKLGYDAEPINNDDDQQTSRKEQELKAKRTKLIISAILSAPLLLMMFVHLLPLHLPAIVMNPWFQFILATPVQFIIGWQFYVGAYKNLRNGSANMDVLVAVGTSAAYFYSLYEMIQWLTHHVNEPHLYFETSAILITLILFGKYLEARAKSQTTNALGELLSLQAKEARILRNNQEVMVALDEVIEGDTLIIKPGEKIPVDGEVIKGSTSIDESMLTGESIPVEKVIGDTVIGSTLNKNGSVHVKATKVGRDTALSNIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIAIVTFIVWIVFVHTGQFEPALLAAISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHHIDTIVLDKTGTITNGKPKVTDYAGDLETLQLLASAEKASEHPLAEAIVTFAEDKGLSLLDNESFNARPGHGIEAMINETHVLIGNRKLMHDFDITIDADNEQKLAQYERQGQTAMMIAIEQELKGIIAVADTVKDTAKQAVSELQNMNIEVVMLTGDNKQTAQAIAQEVGIDRVIAEVLPEQKAEQVSLLQEEGRNVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLLLLPKAIKASKATIRNIRQNLFWAFGYNVAGIPIAALGLLAPWIAGAAMALSSVSVVTNALRLKNMKL
>AP018587.1|BBD94029.1|465870_466077_-|mercuric-ion-binding-protein
MTKETIQVEGMSCEHCKDAVESSLAKLNGVHTAEVNLNEKHVRVVYDDSKVNVAQMKEAIEDQGYDAK
>AP018587.1|BBD94028.1|464632_465793_+|N-succinyldiaminopimelate-aminotransferase
MVISDRLAAIPDSYFGKTMGRKVEHGPLPLINMAVGIPDGETPKGIVNHFSEALRIPENQKYGAFHGKESFKEAIVNFYQRQYGVTLHKDDEVCILYGTKNGLVALPTCIVNPGETVLLPDPGYTDYLAGVMLADAKPVPLELEPPDYLPDWNKIDPQTLKETKLIYLTYPNNPTGSTATQSVFDEAIEKFKDTDTKIVHDFAYSAFGFDAKNPSILASKDGKEVAIEIFSLSKGYNMSGFRVGFAVGNKEMIQALKKYQTHTNAGMFGALQDAATYALNHYDDFLKEQNETFRKRRDMFEAKLQEAKLPFVHSKGGIYSWLHTPPGYNSEEFEQYLLQEKSILVAPGIPFGENGNDYVRISLALDDEQLEEAAERLTQLANMYDV
>AP018587.1|BBD94027.1|462903_464409_+|4,4'-diapophytoene-desaturase
MNIAVIGAGVTGLAAAARLASQGNRVTIFEKNNRIGGRMSQFTKDGFTFDMGPSIVMIPEVYRAVFEECGKNFEDYVEMEQLPYIYDVYFGKNDKVRVPTDLAELQETLESIEPGTTHGFMSFLTDVYQRYEIARYHFLEKTYRKASDFYNLESIIQGLKLKTLNNADNLIENYIDNERIQKLLAFQMLYIGIDPKRGPSLYSIIPMVEMMFGVHFIKGGMYGMTQGLVQLNKDLGVEIQLNAQIDEIIIDPKYKQADGVRVNGLVQRFDKVLCTADFPYAAEKLMPSHSRVKKYKPSKIERLDYSCSAFMMYIGIDKDITDEVMLHNVVFSKRFRQNNDEIFGGRISEDPSIYVYVPAVGDSSLAPKGKTGLYILMPTPELKTGQINWKDESIIEQVKDIIYHQLETIDALEDVRSHVISETVFTPIDFEKEYNAKFGTAFGLMPTLAQSNYYRPPNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVNEMLKDIENGV
>AP018587.1|BBD94026.1|462027_462891_+|squalene-desaturase
MTTNEENFKYCHQIMKEHSKSFSYAFDFLPEQERQAVWVIYAVCRIIDDSIDVHENPQILKDIHEDISYIENTIDISHHEFKSNQSIMVALYVVSQHYTIEYQSFYNLIQSVYEDQNFEMFETDEALLNYCYGVAGTVGEVLTPVLAQSPNKETYATARKLGEALQITNILRDVGEDFENGRIYFSESSLARFDVSIENEFNHRISNQYIDLWEYFAAIAEDDYEIALSNIDTFNKEAQPIIELAAVIYRAILDEVRKASYTLHRRVYVSKLNKAKLYRKIKNKYQL
>AP018587.1|BBD94025.1|460868_461990_+|glycosyltransferase,-group-2-family-protein
MKMIQFILTILSTISLICGRLIFNQRHRLLSSQSPIIHSNEVTIIIPARNEERRLPHLLQSLQGQQGIYEVIVMDDGSKDNTKEIAQTFGATVYETEQNFDRQWFGKSHACYQGATNAQSELLMFVDADVTFGHPHAIEKILNTYRKQHNHGLLSVQPFHETGKFYESLSAIFNLMTVVGVNQFSSLARQSNNDIAFGPITLMHRDDYFKTDGHKNAQHSIIEGFALGEKFESVQLPVTVYEGGNDVKFRMYEDGIQSLIQGWTKHFSVGANKTQPQIMLAIVMWLMGSITSTLTLLISVFTKPASRIVSYLFYVLYTCQFVRLHRRVGAFSMVLLILHPVLFIFFIFIFANSWRHTHFSKKVEWKGRSFKIN
>AP018587.1|BBD94024.1|459371_460862_+|diapolycopene-oxygenase
MTKSVIVIGGGLGGIAAAIRMAQSGFNVKLFEQNNHIGGKVNRLDESGFGFDLGPSILTMPYIFEKLFNYSDKKMSDYVEIERLPLQWRNFFSNGETIDLYENNEATVLNNVQLNEKDKAELDRYFKYTERIYRFTEKGYFNHGLDTLPEILKYHGPLKALHGFDYFSTMQQAIHRYISNPRLREILGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVKGGIHHLAQALEQLAIEEGVELHTGTSVNNIKTYHHNVTGVRLANGDIVEADYIISNMEVIPTYKYLLHFSQQKIDQLEKTYEPASSGYVMHLGVNRSYPQLAHHNFFFSNDSKRNYDEVFHQKVLPQDPTIYLVNSNKTDLQQAPDEFENIKVLPHIPYIQDKPFKKEDYEAFKTRVLTKLEKMGLTDLRKHMIYEDMWTPEDIRQHYHSHRGAIYGVVADKKKNKGFKFPKHSKYFDNLFFVGGSVNPGGGMPMVTLSGLQVADKINAIEAQKE
>AP018587.1|BBD94034.1|469907_470777_+|dehydrogenase
MSLLDFHKEIKGYTQDRQPGIEADMNPKPIAELDEYKAAGKLQGKVALITGGDSGIGRSVAILYAKEGANVAIGYYDEHQDAEDTVRRLEELGVKAKAYAHDLKDEKQSKQLIDNVVKDFGGLNILVNNGGVQFPRDNFEDITPDQVKETFMTNIFGMMFLSQAAVPHLSEGDAIINTTSVTAYRGSGHLIDYSATKGAIVSFTRSLATTLMEKSIRVNAVAPGPIYTPLIPSTFDEEKVENQGGGTPMGRRGQPAELAPSYVFLATHADSSYITGQVIHVNGGDYITT
>AP018587.1|BBD94035.1|470865_471426_+|putative-acetyltransferase
MTEKEKMLAHQWYDANFDDELKKDRLKAKELCFDLNHTRPSDEEKRDRIMNELFGYQTENVGISIPFDTDYGWNVKFGKNVFINTNCYLMDGGGITFGDNVFIGPNCGFYTATHPLNYKERNKGLELAEPIVVGSNTWFGGHVSVMPGVTIGDGSVIGAGSVVTKDIPPNSLAVGNPCKVIKSIEQ
>AP018587.1|BBD94036.1|471589_474097_+|TarF-like-protein
MKNFKNFIANQSRRKINFITSPINMMNKSNYNHQVMTYAKYYGDLKVKDHQILYQVRNGKNITGNPYAIFLYLVNHKEYRRFLHKWVVDSKETLNFYKNKFKNYNNVDFVIIDSSDYLKSLAESKYLINDSTFPLYFAKKENQIYINTWHGTPLKYMGLDMDNNVQGSQNIIKNFLSSDYIISSNRHTTNIFKSAFNLHHIYNGEILEKGYPRIDLTLKNQKSQILNTLKGLISENEEKILLYCPTWRGEDLNNPDINIESILNEAKELEAHLNYKVLVKVHPFIYEEAKKDCDLKNYLIPDYVDTNELLAIVDLMVTDYSSIFFDYLVTNKPIIFYTPDYDDYKFCRGMYINPNELPGPVCTHINDVISSINNKSYENHQIKNNYEKFKTTYVSLEDGHASKNIVEHIFNRKAESPKRNTTRKKTILIYPGGMKNNGITTSIINLLENIDYHQYDITIFLNYSKKEEMLSNLDRVNPNVRIIFRRGPLLASLKECYKVDFVKQRGLQSFLEKLLYPKKVYQREFRKIFGDSHFDYAIDFSGYSMFWANLILASNAKRKLVYLHSDIKADMERRINGVRPHYQNLKGLVSLYPYFDKLVSVSEATSLLNKEKINNPLLSDKYCSSRNTINLNKIHTLVEDDSDRFEKNGESVLINIKNGNVQTVEFSNNDFKIVSIGRLSPEKGFDLLINAVAKLVPKYPNIKLYIMGEGPLKKSLQSLIKKLKMRNHVFLLGHRKNPFYVMKQSNLFALTSHYEGQSMVLLEALTLGVNVLASDIVANRYVLKDGKYGTLVINEIEEIAKGIETFILGQNEKYEKFDAEAYNAKAIKEFYDLLQ
>AP018587.1|BBD94037.1|474148_475090_-|NAD-dependent-epimerase/dehydratase-family-protein
MKALITGGAGFIGSHISERLTNEGVEVHVIDNLSTGRLENIHFIPKEHFYLKDITDVTFVSELIKKEQFDYIFHLAAMVSVVETIEKPVISNETNINATINLLEATRKWDSQIKKFIFASSAAVYGDLPDLPKSTINSKVAPLSPYAIQKFSGEQYAHIYHHLYNVPTVCLRFFNVYGPKQNPNSDYSGVLSILNAKFINKEQFTFYGDGEQTRDFVYIDDLVSAIWTVLYSKDTNGGIFNVGAGSETSLNTVFKSFEKVFGYTIPHIYKECRIGDIKHSYADITPLKRLGYSPQFNIHSGINAYVSYSKNSH
>AP018587.1|BBD94038.1|475285_476011_-|intercellular-adhesion-protein-C
MFHGGAVTYFIVIIFQFYLLHWLFSKYLIGLNPIKMIVISILITTMYWAMRTFISPPNNPILAAIWDREGWMIFIGWLSYFLLGFYIGTYYEAFMNKIKDYTWHIIIGAFLSIIFMFLNYILGISTWVESKRVDTPIYVTMVILLFFLFSSYIKYVPKFIVFISNYSYCIYLIHYFFVHDLGLLSRNPIKNVLFNTIVTLTLAITVGYLFNLFKFGKYIVGGIGKIKYENIYESYQNNNMD
>AP018587.1|BBD94039.1|476159_476345_+|hypothetical-protein
MASKNSDINTNIGVLNINNSWNSRRDVLCGTSCIFEKVVVIEWIITILKQAMERIQKITDV
>AP018587.1|BBD94040.1|476674_478219_+|1-pyrroline-5-carboxylate-dehydrogenase
MVVPFKNEPGIDFSVQDNVDRFNEELKKVKGQLGQDIPLVINGEKIDKSDKFESLNPADTSQLVAKVSKATKDDVENAFKAANEAYQSWKKWSHKDRAELLLRVAAIIRRRKEEISAVMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLADGKPVLDREGEHNKYFYKPIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTVLTAYKLIEILEEAGLPKGVVNFVPGDPKDIGDYLVDHKDTHFVTFTGSRATGTRIYERSSVVQEGQHFLKRVIAEMGGKDAIVVDENIDTDLAAEAIVTSAFGFSGQKCSACSRAIVHKDVHDEVLKKAVQLTKELTLGNTENNTFMGPVINQKQFDKIKNYIEIGKDEGQLEQGGGTDDSTGYFIEPTIFSGLKSSDRIMQEEIFGPVVGFIKVDNFDEAIDVANDTEYGLTGAVITNNREHWIKAVNEYDVGNLYLNRGCTAAVVGYHPFGGFKMSGTDAKTGSPDYLLNFLEQKVVSEMF
>AP018587.1|BBD94041.1|478319_478871_-|TetR-family-transcriptional-regulator
MNENDLRVIKTKKALSTSLYELLEKRSFEVISVNQICNHAMVHRTTFYKHFYDKYDLLVYLFKLLTKDYFSTDLKERLNNPFQTIEATFTNKEELERIEKVQKDDVSFAKIFREFCVDIMKADIKENIHRISVDTAIPENLVFYIYGSTLDGFMEWIKQEDIDWPASEIDAVFHKAINLSISE
>AP018587.1|BBD94042.1|479084_479312_+|FeoA-family-protein
MLNVKNGLKDKKYRIKHIGITNKKMLYRLGAMGVTKGSEISIKQQCLLNGPSIVEINGQYLSIRQSDARLIALED
>AP018587.1|BBD94043.1|479317_481312_+|ferrous-iron-transport-protein-B
MSETFCILGNPNVGKTSLFNALTGSYEYVGNWSGVTVEKKIGKLKGSLGSLIDLPGIYDLSPISKDETVVTDYLLTTNFTGAINIIDASQLKRNMQLTIQLMELNVPLIIGLNMVDVATQRGIKIQFDQLMKRLKIPMFPIVARKSKGTNDILHELEFLKPDDRQVFKIDYGKEIEDAIERMSLIIKTNSNFPKERIRFIAIQYLLDNVQISQKLSDAILEQIAPIKQELNHQSDLYAREQIEKIRNNYINEILEGAVEYPEEEKQFLTATIDKLLINKYLGIPIFLGIMWLIFQTTFTWIGTPLSDQMDSFIGGPFTDWVKLLMNDLHVLPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRTMETIGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLITILIAPFMSCSARLPVYALFVGVFFKAYQSLVVLSLYLLGILVALIVSTILNRCILKNSDSIFIVELPTYRVPSFKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWALTYIGPHGVNVKINQSFIHILGEAVSPIIAPLGFGTWQAGATLIPGFLAKEVIISSMAILYSSSEDGLVHVIQQQFTPLSAYAFMIFILLYVPCISTVETIRKETCSWKWTLFALIYPIITAYGLTLAFYQISKLFI

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Crispr_ID: AP018587_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018587_4

638489-638571

Orphan

Consensus_repeat	Method
AAACTTTAGTTTTTAGATTCGCTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of AP018587_4

>merge|AP018587|4|638489-638571|CRISPRCasFinder
AAACTTTAGTTTTTAGATTCGCTTATGCATTTGTCCAAAGACAAATGTAAACATATGGAAACTTTAGTTTTTAGATTTGCTTA

>AP018587|4|3|638489-638571|CRISPRCasFinder
AAACTTTAGTTTTTAGATTCGCTTA	TGCATTTGTCCAAAGACAAATGTAAACATATGG
AAACTTTAGTTTTTAGATTTGCTTA

Protein	Signature genes	Signature genes Name	Protein_function
AP018587.1\|BBD94200.1\|645190_646468_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224428
AP018587.1\|BBD94190.1\|635269_635716_-\|HTH-type-transcriptional-regulator-SarZ	unknown	unknown	gnl\|CDD\|197670
AP018587.1\|BBD94187.1\|632273_632930_+\|oxygen-regulatory-protein-NreC	unknown	unknown	gnl\|CDD\|225107
AP018587.1\|BBD94191.1\|635880_636510_+\|NAD(P)H-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|380314
AP018587.1\|BBD94192.1\|636630_636996_+\|exported-protein	unknown	unknown	gnl\|CDD\|371476
AP018587.1\|BBD94189.1\|634563_634980_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
AP018587.1\|BBD94184.1\|630060_630738_+\|nitrate-reductase-gamma-chain	unknown	unknown	gnl\|CDD\|376889
AP018587.1\|BBD94193.1\|637175_638456_+\|proton/sodium-glutamate-symport-protein	unknown	unknown	gnl\|CDD\|183075
AP018587.1\|BBD94188.1\|633284_634460_+\|nitrite-extrusion-protein-NarK	unknown	unknown	gnl\|CDD\|225133
AP018587.1\|BBD94195.1\|639169_639592_-\|general-stress-protein-26	unknown	unknown	gnl\|CDD\|226389
AP018587.1\|BBD94202.1\|647624_648044_+\|MarR-family-regulatory-protein	unknown	unknown	gnl\|CDD\|197670
AP018587.1\|BBD94196.1\|639662_641696_-\|putative-transcription-regulatory-protein	unknown	unknown	gnl\|CDD\|197666
AP018587.1\|BBD94198.1\|643399_644347_-\|cationic-transporter	unknown	unknown	gnl\|CDD\|213361
AP018587.1\|BBD94201.1\|646655_647438_+\|putative-oxidoreductase	unknown	unknown	gnl\|CDD\|187610
AP018587.1\|BBD94197.1\|642778_643156_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377982
AP018587.1\|BBD94185.1\|630748_631210_+\|putative-nitrogen-regulatory-protein-A	unknown	unknown	gnl\|CDD\|379056
AP018587.1\|BBD94203.1\|648181_649540_+\|multidrug-export-protein-MepA	unknown	unknown	gnl\|CDD\|240548
AP018587.1\|BBD94194.1\|638640_638991_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374445
AP018587.1\|BBD94199.1\|644416_645028_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274100
AP018587.1\|BBD94186.1\|631219_632254_+\|oxygen-sensor-histidine-kinase-nreB	unknown	unknown	gnl\|CDD\|226951

Protein	Function_ID	Function_description	E-value
AP018587.1\|BBD94200.1\|645190_646468_+\|hypothetical-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	4.71672e-38
AP018587.1\|BBD94190.1\|635269_635716_-\|HTH-type-transcriptional-regulator-SarZ	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.74818e-18
AP018587.1\|BBD94187.1\|632273_632930_+\|oxygen-regulatory-protein-NreC	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.31816e-76
AP018587.1\|BBD94191.1\|635880_636510_+\|NAD(P)H-flavin-oxidoreductase	gnl\|CDD\|380314	cd02137, MhqN-like, nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN. A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	9.5178e-59
AP018587.1\|BBD94192.1\|636630_636996_+\|exported-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	4.55826e-10
AP018587.1\|BBD94189.1\|634563_634980_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	9.88001e-26
AP018587.1\|BBD94184.1\|630060_630738_+\|nitrate-reductase-gamma-chain	gnl\|CDD\|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	1.86256e-108
AP018587.1\|BBD94193.1\|637175_638456_+\|proton/sodium-glutamate-symport-protein	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	2.84466e-164
AP018587.1\|BBD94188.1\|633284_634460_+\|nitrite-extrusion-protein-NarK	gnl\|CDD\|225133	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism].	2.89092e-110
AP018587.1\|BBD94195.1\|639169_639592_-\|general-stress-protein-26	gnl\|CDD\|226389	COG3871, COG3871, Uncharacterized stress protein (general stress protein 26) [General function prediction only].	2.20238e-43
AP018587.1\|BBD94202.1\|647624_648044_+\|MarR-family-regulatory-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.08367e-20
AP018587.1\|BBD94196.1\|639662_641696_-\|putative-transcription-regulatory-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.22254e-20
AP018587.1\|BBD94198.1\|643399_644347_-\|cationic-transporter	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	3.93329e-108
AP018587.1\|BBD94201.1\|646655_647438_+\|putative-oxidoreductase	gnl\|CDD\|187610	cd05352, MDH-like_SDR_c, mannitol dehydrogenase (MDH)-like, classical (c) SDRs. NADP-mannitol dehydrogenase catalyzes the conversion of fructose to mannitol, an acyclic 6-carbon sugar. MDH is a tetrameric member of the SDR family. This subgroup also includes various other tetrameric SDRs, including Pichia stipitis D-arabinitol dehydrogenase (aka polyol dehydrogenase), Candida albicans Sou1p, a sorbose reductase, and Candida parapsilosis (S)-specific carbonyl reductase (SCR, aka S-specific alcohol dehydrogenase) which catalyzes the enantioselective reduction of 2-hydroxyacetophenone into (S)-1-phenyl-1,2-ethanediol. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser).	1.33097e-100
AP018587.1\|BBD94197.1\|642778_643156_-\|hypothetical-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	5.07591e-19
AP018587.1\|BBD94185.1\|630748_631210_+\|putative-nitrogen-regulatory-protein-A	gnl\|CDD\|379056	pfam13185, GAF_2, GAF domain.	8.72924e-07
AP018587.1\|BBD94203.1\|648181_649540_+\|multidrug-export-protein-MepA	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	2.52563e-105
AP018587.1\|BBD94194.1\|638640_638991_-\|hypothetical-protein	gnl\|CDD\|374445	pfam16230, DUF4889, Domain of unknown function (DUF4889). This family consists of uncharacterized proteins around 110 residues in length and is mainly found in various Staphylococcus aureus species. The function of this family is unknown.	7.06458e-26
AP018587.1\|BBD94199.1\|644416_645028_-\|hypothetical-protein	gnl\|CDD\|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	5.52427e-10
AP018587.1\|BBD94186.1\|631219_632254_+\|oxygen-sensor-histidine-kinase-nreB	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.20968e-58

>AP018587.1|BBD94193.1|637175_638456_+|proton/sodium-glutamate-symport-protein
MALFKRKISLPTQVIIALVLGVIAGLLLFGQDNVANYIKPFGDIFLNLIKMIIIPIVFCALALSISNLGDSKKVGSYGWKAILYFEIITTVAIGLGIIIGNLFKPGSGLDPDKLPKGDISKYQSSAQSAEQATTYGNHLIDTIVNIVPTNLFESLAKGDLLPIIFFAAFFGLGLAAIGEKAEPVKGFLNGTLEAVFWMINKILKLAPIGVFAFICTTVMTFGASALIPLLKLLVVVVFAMIFFVVVVLGIVARMVGVSIFSIMKILKSELLLAFSTSSSEAVLPVIMKKMEKFGAPKDVTSFVIPIGYSFNLDGSALYQSIAALFVAQMFDIHLSLTQQIVLMATLMIASKGMAGVPGVSIVVLLTTLGSMHLPAQGLALIIGIDRLLDMVRTCVNVMGNALSTIVISKWENVYDKEKGQEYLKTL
>AP018587.1|BBD94192.1|636630_636996_+|exported-protein
MSRKQVIFRIIIILIISLILAVVFFFGLKTYQGHKNIELMDSYIKEHHLQDKIKKQETLYSAKKGMYYKQIVYKDEPNVTYVLQPISTNKGIFSEGFDSETKKSIKKAKHSDFDKNYKPSK
>AP018587.1|BBD94191.1|635880_636510_+|NAD(P)H-flavin-oxidoreductase
MSRINDFNEILNERKSVKVFDSDYKIPHEEMDEIIIKATKAPSSVNMQPWRIVVVDSDEGKAKLKDAFGFNSRQLTTSSAMIIIFGDLQNYEKAEQIYSDAVDQQHMTEEIKTQMLEWILPYYKGLSKEGMKDIVNIDSSLMAMQFMLTAKAYGYDTNPIGGFDKENIAEIIGYDSERYIPVLAIAIGKKAQEAHSSVRLPVHEIREYL
>AP018587.1|BBD94190.1|635269_635716_-|HTH-type-transcriptional-regulator-SarZ
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYELTYTGYIVLMAIEDDEKLNIKKLGERVFLDSGTLTPLLKKLEKKNYVVRSREEKDERNLQISLTERGKEIKKTLSDISMKVYSEFNINQDEAKELIANLQNFVSKNFDKNLEK
>AP018587.1|BBD94189.1|634563_634980_-|Hsp20/alpha-crystallin-family-protein
MNSNEFFNNNFFKNDPSELFKDIGKQVYNQFSSSAFPTNIYDTDEAYIVEAELPGVSKEDISLKFEQNILLIKANKKLKNENQKIQLNERSTGELERHFKFDDINKEAITANHAEGVLYVTLPKVIDEDEKATTIAIQ
>AP018587.1|BBD94188.1|633284_634460_+|nitrite-extrusion-protein-NarK
MKKGVYQLTLQTLSLIVGFMAWSIISPLMPFITQDIQISASQVSVILAIPVILGSVLRVPFGYLTNIIGAKWVFFSSFIILLFPIFFLGQAQSTTMLMVCGFFLGVGGAIFSVGVTALPKYFSKDKVGLANGIYGMGNIGTAISSFCAPVLAGLIGWQSTVRSYLIIIGLFAVLMFLLGDNKETKVKVPLMSQMKVLSKNYKLYYLSLWYFITFGAFVAFGLFLPNYLVHHFEIDKVDAGIRSGVFIALATFLRPLGGVLGDKFNAVKMLIIDFMFLIIGGMILSLFDGMIHFTIGCLAISICAGIGNGLVFKLVPSYFSKEAGSANGIVSMMGGLGGFFPPLVITFVTGLTGSSHLAFGLLVLFALIALMTMIHLYKKENVSNISTIYDK
>AP018587.1|BBD94187.1|632273_632930_+|oxygen-regulatory-protein-NreC
MKIVIADDHAVVRTGFSMILNYQEDMEVVATAADGVEAYQKVLEYRPDVLILDLSMPPGESGLVATSKISESFPETKILILTMYDDEEYLFHVLKSGAKGYILKNAPDEQLILAVRTVYRGETYIDMKLTTSLVNEFINQSNQEEVNYSSDPFKVLSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMNKLNLKSKPELVEYALKKKLLEF
>AP018587.1|BBD94186.1|631219_632254_+|oxygen-sensor-histidine-kinase-nreB
MQSKLEGSIEALLHKYYDATTEKIVFVNHLGKIIAMNDAASDILSEEDNYNAMTHAICNRCEGYSNEYDIQSCENCFLEENQLQKSNFQVFMKTKDNKVEPFTATYQTIDSDRGISAFTLQNVSPQIERQEKMYQQKMLHKSIQAQENERKRISRELHDSVIQEMLNIDVELRLLKYKYQDENLVDSAQHIEGLVSQLIDDIRNLSVELRPSSLDDLGIEAAFNSYFKQFEENYGIQINYQSNIKGMRFDNEVETVVYRVIQEAVLNSLKYAEVNEIEVNINKSDNRLLAEVVDRGKGFNIEDKPKGSGLGFYGMKERAELVNGNINIESHINKGTIVTLDIPI
>AP018587.1|BBD94185.1|630748_631210_+|putative-nitrogen-regulatory-protein-A
MGKLKPESLLHNKSLQDNLDRLRKNEGYDFGAIAMYEHYHRSSPIKWKYVSGNTNERYKLIILRKGRGLAGTVMKTGKRMVIADVDMALTQAEKIKFPIILNEALTAVVAVPLWLDEQMYGVLLLGQRNHQPLPQTLEQLDIQSQIGFFTEMN
>AP018587.1|BBD94184.1|630060_630738_+|nitrate-reductase-gamma-chain
MLNQFIWIIYPYLCLTIFIIGHLARYKYDQFSWTAKSSELIEKKQLKWGSLLFHLGVIPVFFGHVVGLLVPANWLEAVGVNNHIYHIGAVYIGSIFGIITLLGMMLLTLRRLTIKNVRRLSSFSDIFVNILLCIILIMGCYSTIFTNAVQPDFDYRQTIAIWFRHLFMFSPNADLMLNVPLSFKVHILLGFTIFALWPFTRLVHVWSVPLSYMNRRYIIYRKNKV
>AP018587.1|BBD94194.1|638640_638991_-|hypothetical-protein
MKNKKALGFGLIAIMLIVCIVLVIMMMTGGKKDTYYGIMKNSTTIDKMISEKDEKIEKNVKLPSNANVSVKKEDFVMIFKDEKSGKITKVKKVDHDDVPHGLMSKIHDMKGMHHGM
>AP018587.1|BBD94195.1|639169_639592_-|general-stress-protein-26
MDKQQATQAIEKVLDNSKVGVLSTAYNNKPNSRYMVFYNDDLTLYTKTNINSVKVEEIEDNPYAYILLGYNETTNNSFVEIDAQIEVVKDQKVIDWLWETQDKTFFDSKQDPELCVLKVQPKSIKLMNDDDLDTPITIEV
>AP018587.1|BBD94196.1|639662_641696_-|putative-transcription-regulatory-protein
MFSLTNDLKITINGETKDLDNHIAIINQTDIYYVNQSSNLVTLSIPVFYFYNEDNQFFKCYFDRHLLQSSGFVKNIILQSIHRFMNNEEQDNQAISKIIQTLYKESVIRYKGKYIPKVAINHPIFVEGLTYIHTKVSEMLSLRQVAQHCNISESYCSNLFVRYLNMNFKDYFTSLKVIHAIKLLLSTDDSINAISEHSGFSSHTNFTNQFKNYLGFSPKQFRSYISKIELNPTIQFINENYSEFKDLINQFEFNDQLATEITEKDIDQFNPKDRTKSSKAFIRFENFNELFQFVFNEYYDIDFSYLPQPVVFIQDISDIVVSHINFNLLNRCFEKLFEKDIGLAMKIKTTQQFEAINQVILSFLQSNQDYKTNKKLVKLMLVFDSESMSVNEIHLCHLKIKNKNREIRYGMTVEGLLRESASIDHTYDIMKRLNFDYYFIDIENLETKNLLLNKRKTYHHSSTHFENYKQFMLDSGISSTRFVYNNLSLKCFKYTNNGANPLQLSDLVCHLIALMRYGGGISYQLIDDDSQYISLFNSYGSPLPLMHIYKMVASFVDEPLEVGNNYLMSRKGGNYHFLLFNKINDRYLSDSKQKFIFKNQLNVNSLIIINTLNNEHGSIQNLLPKSKELLYIERSILEELDKCNHPKTELAVQEENHKPFQLTLKHDEVKYICIKPL
>AP018587.1|BBD94197.1|642778_643156_-|hypothetical-protein
MKERGKIEKLWSEEKYHVLLHHQHAYDNIRDMLKGDPSLKEVQNEIANALAITPTKGSIINAYDHMWGYFKKVATDEEQHKALLLKNKFNDNQLNQLTLLNYLKELSDKYEVRYLQNSTVLKQLK
>AP018587.1|BBD94198.1|643399_644347_-|cationic-transporter
MITAYKHASSNSNEIIETTVDHSASWINVVEPEREEIENLMEFYNIPEDFIRDPLDSEESARIEYDEDTGYSLIIIDLPIVNSTNRRVLSFVTIPLGIIIGNGMIMTVCDAENEFLENFARQDDIHLNFHSRFALEILLTIANHYNRNLRLLNKSRIRIEKDLKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLVIENNQAIETTELHQRILESITTSYASLLSNDMNTIMKTLTLFTVLLTLPTLVFSFFGMNVPLPIDAHSYASWVIVVGISLILVAIVSIFLWRKQKL
>AP018587.1|BBD94199.1|644416_645028_-|hypothetical-protein
MKEDRRIRKTKSSIKKAFTTLLQNKDLDKITIRDITSEADVNRGTFYLHYEDKYMLLTDMEDECISELSHLTHFNHINGETVEEISQLFIENVLTKILQHIDDNLEFYHTILQLERTSKLEEKISELMKENMSRYMSINHEIDGIPEMYFHSYVAGATINTIKYWVLDPHRISVEELTHHIYKIVFNGPLRIMAEYKYQKNNA
>AP018587.1|BBD94200.1|645190_646468_+|hypothetical-protein
MNIFKSKLLWFAPIAAIVILVIFSLAFYPAFNPKPKDLPIAIVNNDEGTTIQSNKVDIGKKIEDKLLDSDSDKIKWVKVDKESDLQKGFDNEKYYGAVVFEKDFSKNAMSKTQKVVMDSKKSEMKEKVESGEIPAQQAQKMKQKMGNQSVDVKQANLKTIVSQGSNLQASNIVTNVLSGIGENLNKQITKQSLSTLQKQNVDVSPKDIQGITNPVKVDNQKVNKVKDHQGGGNAPFLMFMPVWMGSMITSVLLFFAFRTSNNFAIQHRIIASVGQMVTTVIAAFLGSFAYIYFMKGVLGFHFDHPNRVALFIALAIMGFVGLILGIMVWLGMKSLPIFILLMFFSMQMVTLPKQMLPGGYQKWAYGWNPFTHYTTSLKELIYMNKAIELNGTMWVFIGFMIFGIVSSLVAAIVRKHSTKRTEVPS
>AP018587.1|BBD94201.1|646655_647438_+|putative-oxidoreductase
MMSVLDQFKLDDKVAIVTGGASGLGKAMGKALAEAGANLVIADMNLEVGQETAKEFEEATDNKAIACEVDVTNLEQVNAMVKETMDTFGHIDILFNNAGINEHVKFEDMPYDRWKKTMDVNLNSMVLVTNAVGEVFRKQQHGVIVNTSSMSGVIVNSPQPQAAYNTSKAAVIMLTKSLANEWAEHNIRVNTIAPGYMKTELTKDYFAKGGDMIDTWMNMTPMKRPGVPEELQGAALYLASDASSFVTGSVITVDGGYTAL
>AP018587.1|BBD94202.1|647624_648044_+|MarR-family-regulatory-protein
MNLTFQYLIRSLAHQMKNYADKRLDDFGITQEQSHTLGYIYRHQEEGMTQKTLLEAFDRKGSTVSSTLKILESKGLIYRKVNPKDTRSKLLKLTDEGITLVESFIKIFDEIEENMLKDFTDNDKEKLREYFDRMMNNLK
>AP018587.1|BBD94203.1|648181_649540_+|multidrug-export-protein-MepA
MKDEQLYYFEKSPIFKAMMHFSIPMMIGSLLSVIYGILNVYFIGFLDNSHMISAISLTLPIFAVLMGFGNLFGVGGGTFISRLLGAKDYSKGKHVGSFSTYAGFILGIIIAMIALPFTDQIAHILGASGETLTYTSNFLKVMFLSSPFVIVFFILEQFARAVGKPIISMIGMLSSVVLNMILDPIFIFGLDLNVVGAALGTAISNVVAALFFVIYFSKNNESISLRLKDATPTSEMLAEIFKIGIPAFLMVVLMGVTGLVLNLFLAKYGNYAIASYGIQFRLVQFPELIIMGLSEGVIPLIAYNFVSNKDRMKDTIKAVIISIAIIFVISMSVVLLFGHQIIQLFSTDVHIVHLATFMLKVTMTSLLLNGIGFLFTGMLQATGQGRGATIMAILQGTVIIPVLFVMEHLFGLTGVVWSLLIAETLCALAAMLIVYLLRNQLAVDRDELLAEA

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Crispr_ID: AP018587_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018587_5

1086660-1086782

Orphan

Consensus_repeat	Method
ATTAAGCGGGAGTAGTTCAACTCTTAGAACAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of AP018587_5

>merge|AP018587|5|1086660-1086782|CRISPRCasFinder
ATTAAGCGGGAGTAGTTCAACTCTTAGAACACATTCCTTCCCGGAATGAGATATAGGTGCAAGTCCTATCTTCCGCTCCATTAAATTTTATATTAAGCGGGAGTAGTTCAACTTTTAGAACAC

>AP018587|5|4|1086660-1086782|CRISPRCasFinder
ATTAAGCGGGAGTAGTTCAACTCTTAGAACAC	ATTCCTTCCCGGAATGAGATATAGGTGCAAGTCCTATCTTCCGCTCCATTAAATTTTAT
ATTAAGCGGGAGTAGTTCAACTTTTAGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
AP018587.1\|BBD94643.1\|1077456_1078407_+\|putative-D-3-phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
AP018587.1\|BBD94640.1\|1074044_1075139_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
AP018587.1\|BBD94645.1\|1083744_1083906_+\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94649.1\|1089232_1090291_+\|regulatory-protein-PfoS/R-homologue	unknown	unknown	gnl\|CDD\|226167
AP018587.1\|BBD94655.1\|1095169_1095349_+\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94641.1\|1075622_1076915_-\|glutamate-1-semialdehyde=2,1-aminomutase-2	unknown	unknown	gnl\|CDD\|183493
AP018587.1\|BBD94644.1\|1078502_1078958_+\|FUR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223806
AP018587.1\|BBD94638.1\|1071384_1071927_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184219
AP018587.1\|BBD94656.1\|1095584_1095983_+\|membrane-protein	unknown	unknown	unknown
AP018587.1\|BBD94648.1\|1088566_1088887_-\|DNA-binding-helix-turn-helix-protein	unknown	unknown	gnl\|CDD\|238045
AP018587.1\|BBD94647.1\|1087617_1088355_-\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD94637.1\|1070237_1071281_+\|putative-A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
AP018587.1\|BBD94636.1\|1069107_1070085_-\|putative-inner-membrane-protein	unknown	unknown	gnl\|CDD\|224899
AP018587.1\|BBD94642.1\|1076995_1077451_+\|putative-bacterioferritin-comigratory-protein	unknown	unknown	gnl\|CDD\|224146
AP018587.1\|BBD94654.1\|1094545_1095145_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223440
AP018587.1\|BBD94652.1\|1092765_1093893_+\|iron-sulfur-(Fe-S)-cluster-binding-protein	unknown	unknown	gnl\|CDD\|272993
AP018587.1\|BBD94653.1\|1093895_1094366_+\|putative-tRNA-(cytidine/uridine-2'-O-)-methyltransferase	unknown	unknown	gnl\|CDD\|349967
AP018587.1\|BBD94639.1\|1072209_1073946_+\|ABC-transporter-(ATP-binding-protein)-homolog	unknown	unknown	gnl\|CDD\|224055
AP018587.1\|BBD94650.1\|1090433_1091891_+\|polar-amino-acid-ABC-transporter,-inner-membrane-subunit	unknown	unknown	gnl\|CDD\|223836
AP018587.1\|BBD94651.1\|1091883_1092606_+\|glutamate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051

Protein	Function_ID	Function_description	E-value
AP018587.1\|BBD94643.1\|1077456_1078407_+\|putative-D-3-phosphoglycerate-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.74728e-144
AP018587.1\|BBD94640.1\|1074044_1075139_-\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	2.84888e-70
AP018587.1\|BBD94636.1\|1069107_1070085_-\|putative-inner-membrane-protein	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.79709e-35
AP018587.1\|BBD94649.1\|1089232_1090291_+\|regulatory-protein-PfoS/R-homologue	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.2288e-106
AP018587.1\|BBD94641.1\|1075622_1076915_-\|glutamate-1-semialdehyde=2,1-aminomutase-2	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
AP018587.1\|BBD94644.1\|1078502_1078958_+\|FUR-family-transcriptional-regulator	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	5.06473e-55
AP018587.1\|BBD94638.1\|1071384_1071927_+\|hypothetical-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	2.13956e-126
AP018587.1\|BBD94648.1\|1088566_1088887_-\|DNA-binding-helix-turn-helix-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.56373e-11
AP018587.1\|BBD94637.1\|1070237_1071281_+\|putative-A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.83399e-139
AP018587.1\|BBD94642.1\|1076995_1077451_+\|putative-bacterioferritin-comigratory-protein	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	5.77029e-64
AP018587.1\|BBD94654.1\|1094545_1095145_+\|hypothetical-protein	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	5.89087e-09
AP018587.1\|BBD94652.1\|1092765_1093893_+\|iron-sulfur-(Fe-S)-cluster-binding-protein	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	4.99817e-180
AP018587.1\|BBD94653.1\|1093895_1094366_+\|putative-tRNA-(cytidine/uridine-2'-O-)-methyltransferase	gnl\|CDD\|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	3.1433e-86
AP018587.1\|BBD94639.1\|1072209_1073946_+\|ABC-transporter-(ATP-binding-protein)-homolog	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
AP018587.1\|BBD94650.1\|1090433_1091891_+\|polar-amino-acid-ABC-transporter,-inner-membrane-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.5602e-96
AP018587.1\|BBD94651.1\|1091883_1092606_+\|glutamate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	6.65838e-152

>AP018587.1|BBD94645.1|1083744_1083906_+|hypothetical-protein
MSGGQFDWGGRLLKGNGGAQRFPQNGWKSFTECKGIRELDCETYKSSRVERRT
>AP018587.1|BBD94644.1|1078502_1078958_+|FUR-family-transcriptional-regulator
MSADLESIEHELEESIASLRKAGIRITPQRQAIIRYLISSHSHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDASSRFDFNTHNHYHVICEKCGKIVDFHYPQLDEVEHLAQHVTDFDITHHRMEIYGTCKECKEKDNN
>AP018587.1|BBD94643.1|1077456_1078407_+|putative-D-3-phosphoglycerate-dehydrogenase
MKIVSLIRLKDLEDELIKKFPNEEFKFYKKAETIPTEDRETLDILIGYDGSIDKAFIEECKNLKWIAWYATGVNNLPLDYINERGIIVTNGRGVQAKQLSEYIIAFILDDYKKMRTSYENQLAHRFDSKLTGHRVNGETLLFLGTGAIAQKTAYLAKAFGMKIVGVSKSGHMKDHFDETYTIEEIDKVIGEANIIVNSLPETNETIHLLQKHHFEQMRDDALFINIGRGTVVDELLLIDVLRNQIIRHAYLDVFENEPLASDNPLYDLNNVTITAHITGNDKHINRDVTAIFEKNLKHFLNKNDVIENRVDLNKGY
>AP018587.1|BBD94642.1|1076995_1077451_+|putative-bacterioferritin-comigratory-protein
MLNKGEQFPSFSLENQNGEVITNETLKGRKAILYFYPRDNTPTCTTEACDFRDHLSDFNELDVDVYGINGDSKKKHQNFIEKHQLNFDLLVDEDYKLANEVGVYQLKKSFGKESMGIVRTTFVIDENGYIMDVIEKVKVKTQIEELKNILG
>AP018587.1|BBD94641.1|1075622_1076915_-|glutamate-1-semialdehyde=2,1-aminomutase-2
MNFTESERLQELSNEYILGGVNSPSRSYKAVGGGAPVMMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITEAIQDQAAKGVLYGTPTELEIDFSKKLREAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPQSVAQEVITVPFNDIESYREAIDYWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNKISHDNGTLVIYDEVITAFRFHYGAAQDLLGVKPDLTAFGKIVGGGLPIGGYGGRQDIMEHVAPLGPAYQAGTMAGNPLSMRAGIALLEVLEQDGVYEKLDQLGRRLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKITHYEQVENSDGEAFAKFFKLMLHQGINLAPSKFEAWFLTTEHTEEDIDQTLEAADYAFSQMKN
>AP018587.1|BBD94640.1|1074044_1075139_-|hypothetical-protein
MRLGARIFKTGIAIILAMSIASLLPANIGLKALAGVSAVVAMQPSVYRSIKTVSEQAIGNIIGAILAVTMVTIFSNNFIIMGVTVILLIAILFKFNLAHVATLASVTALVIMGQHTGSFYVAAFFRFALVMIGVLSSSIVNLVFLPPKFETKIYYNSMNISSDIFVWFKLVLNDTSEFHNIKQDCSQLNSRITKLEQIYDYYNEEKPLTKKHIYQQNRKKILFKEVVRTTRQAYEVLNRMSRFQNDLHQLNNQLLLQIKLELDSLVAVHEQIYKSLSKKAKYDVTQLDYEVDNPQKKNLMDAFQQELINNPHQTRYSYGNMMQIIAAIEEYRYHLEHLDRIRLSFFTYHRSDSDIDISDEDFDL
>AP018587.1|BBD94639.1|1072209_1073946_+|ABC-transporter-(ATP-binding-protein)-homolog
MIKRYLKFVQPYRYRIIATIIVGIIKFGIPMLIPLLIKYAIDGVINNHSLSNSEKFSHLGVAIGIALFIFLIVRPPIEYIRQYLAQWTSNKILYDIRKQLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCVTIIIALSIMFFLDVKLTIAAIFIFPFYILTVYFFFGRLRQLTRVRSQALAEVQGFLHERVQGMSVIKSFAIEDNEAKNFDHRNGHFLKRAFQHTRWNAYSFAAINTVTDLGPIIVIGVGAYLVINGSITVGTLAAFVGYLEQLFGPLRRLVSSFTTLTQSFASMDRVFQLMDEDYDIKNGIGAQPIEIKKGQIDLNHVRFKYNENESEVLHDINLTINKGETVAFVGMSGGGKSTLISLIPRFYDVTAGEINIDGNNVKDFLTGSLRNQIGLVQQDNILFSDTVRENILLGRPDATEEEIVEAAKMANAHDFIINLPEGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESEAIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVMENGQIVETGTHQELIAKKGAYEHLYSIQNL
>AP018587.1|BBD94638.1|1071384_1071927_+|hypothetical-protein
MVKESIPKEGESIKIQSYKHDGNIHRVWSETTILKGTDHVIIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDVILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRDY
>AP018587.1|BBD94637.1|1070237_1071281_+|putative-A/G-specific-adenine-glycosylase
MYQNESFKKNIVDWFEKNQRDLPWRETTNPYYIWLSEVMLQQTQVNTVIDYYYRFIHRFPTVASLSEAHEDEVLKYWEGLGYYSRARNFHTAIKEVEAQYDGEVPSEPELFKKLKGVGPYTQAAVMSIAFDQPLATVDGNVFRVWSRLNNDYRDTKLQSTRKAFEQELNPYVQEASGTFNQAMMELGALICTPKSPLCLFCPVQENCEAFHEGTTQELPVKTKNIKKKTVNQKVLLIRNSKGQYLLEKRQEKLLNGMWQFPMREESDADAQLSDYLGLHVQSLEEPIYELRHQFTHMTWNIKVYSVPETHDIPDDELPSNMKWFDLDDREAHTFPVSMDKIYRFIVG
>AP018587.1|BBD94636.1|1069107_1070085_-|putative-inner-membrane-protein
MDTATHIVMGVGLTALATQDPVMAGSFAATATTLVAGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFVIFNHTEPLHVWLWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVISTFDPIIFTLLCIGVLLWIVGVHPYLAFFPIVAILIVYYIVRFMMQATIKKEALKRIDRSHNAVKVFVAPTIKFHVWRVAIQTEQHDYVGTARWKDVEFTDKVKRQSMTPDTLLWKVKGNKDIFTFLNFSSIYRWQTTPLEDGATEIRLMDLRYLNNGRYSFVAIAHLTQDNEIDHSYIGWVFSEDKLQRKLYSQ
>AP018587.1|BBD94647.1|1087617_1088355_-|hypothetical-protein
MLLYLFFTLLIIFAVSTVVLIILLIISKVNKKSIKPYVISTSITLVLTIIFLVLTIFFHHINERNKKEMYPPKTVELKDGSYEVGKDLEPGHYTISSKNNKGYIEIKTVEDWSFEEKFGKDYGTLDNATTPTITTYLMEGDKINLDKAELTTFKPKHQTFTNPISTGVWIVGKDVKPGKYKIYTTFSHDIGGNFKIFNRDGSLDKEYILVGKDSDRPYDTEGAVTLKSGQILILNHMYSVSLEKK
>AP018587.1|BBD94648.1|1088566_1088887_-|DNA-binding-helix-turn-helix-protein
MSAKSARTIFSENLQRLMRNKNVDQKELAETIGVTQPTISNWIKEIKYPRIKRIQLLADYFNVPKSELTEEHSIVTKNAIAAYITPDVTEEEMKEIINFIEYIKSK
>AP018587.1|BBD94649.1|1089232_1090291_+|regulatory-protein-PfoS/R-homologue
MSNSHVNGKSFFNNILNAVGAGVVIALLPNALLGELLKFFKEGNHLLETVYQLVIVIQSFMAFIIGVLAAHQFKFKGAGAAIIGTSAMLGSGVVHFSNKGIELKGIGDIINVIVVVALACFIYMFLEGKLGSFEMIILPVLVPVISGVIGLLTLPYVQVITQSIGRVVNGFTELNPLLMSILICVTFSLLMVTPISLVAIATAISLTGLGSGAANMGIVAACVTFLFGSLRVNSIGVNLVLLIGAAKMMIPVYLKHLIIAIPLTVNGIICGIVAYVLNIKGTPLSAGFGYTGLVGPINALNRMSGDTSFNIIMLIIGYFVVPFTGAFIVHHLCKKFIHSYSDEIYQFEIPKE
>AP018587.1|BBD94650.1|1090433_1091891_+|polar-amino-acid-ABC-transporter,-inner-membrane-subunit
MNKTFKIIIVIAILISSAMIYINPIASAKEDSNWNKIKQRGEIRVGLSADYAPLEFEKTVHGKTEYAGVDIELAKKIAKDNHLKLKIVNMQFDSLLGALKTGKIDIIISGMTTTPERKKEVDFTEPYMMTNNTMLVKKSEKNQYKSLKDFDGKKIAAQKGTEQEKIAQNEINNGQISSLSRLPDAILALKSGKVVGTVIEKPVAEAYLKQNPELDFADVKFNEEKKPTCIALPKDSPELLKHLNQTIDEVKSKNLIDSYMNKAAEDMQDDGNFFTKYGSFFIKGIKDTILISSIGVILGSILGALIALMKLSKFKPLSWLASIYIEFLRGTPMLVQVFIVFFGTTAALGLDVSALICGTIALVINSSAYIAEIIRAGINAVDKGQTEAARSLGLNYSQTMKFVVMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLIAAVLYFILTFALSRIMSLVEGRMKASD
>AP018587.1|BBD94651.1|1091883_1092606_+|glutamate-ABC-transporter-ATP-binding-protein
MIKIKNLNKTFGHNEVLKDINLEVKQGEVVAIIGPSGSGKSTLLRCMNLLETPTKGQVIFEGNDLTEKNVHLDELRQKMGMVFQSFNLFPHKKVIENIMLAPKLLHKDNQGTIKEIALNLLDKVGLKDKAEAYPNQLSGGQKQRVAIARALAMKPDVLLFDEPTSALDPEVVGDVLKVMRDLAKDGMTMVIVTHEMNFAKEVSNKVVFMADGVVVESGSPVDIFEHPQHERTQNFLSRVL
>AP018587.1|BBD94652.1|1092765_1093893_+|iron-sulfur-(Fe-S)-cluster-binding-protein
MDYKQLKREIIDYAHSIGIDSIGFTTADPFDELKQKLESYHSRGYASGFEESDIALRTEPKLSLPSARSIIAIAVGYPNKLKGAPKSVRGDRRGMFARASWGQDYHTIMRKRLDKLSEFLRERVPNVEIQSMVDTGVLSDRAVAERAGLGFVGRNGFVISPELGTWTYLGEMLVSIPFEPDDPILDSCGDCTICVDRCPTGALVGNGQLNSQKCISFLTQTKGYLEDEYRYKIGNRLYGCDTCQQVCPKNRGINTQHDDIVLEPEILKPRLVPLLQMSNKEFKNTYGHLAGAWRGKKPIQRNAIIALAHFKEENAIPELKEVALNDPRPMIRGTAYWAIGQIQGEDARHFINENFEKEIEEVQVEMKKGLEMRRD
>AP018587.1|BBD94653.1|1093895_1094366_+|putative-tRNA-(cytidine/uridine-2'-O-)-methyltransferase
MTNHIVLFQPEIPANTGNIARTCAGTLTHLHLIKPLGFSTDDKMLKRAGLDYWEHVNITYHESIEAFFESTEGNYYLLTKFGKQTYSDFNFSNTEEEHYFIFGRETTGLPNWVKEKYADTALRIPMSDKIRSLNLSNTAALLIYEALRQQQFPNLS
>AP018587.1|BBD94654.1|1094545_1095145_+|hypothetical-protein
MAMNFKVFDNNERVAEYAADIIRKQFNNNPTTIAGFHLDKDQAPVLDELKKNVDTHAVDFSQINILDYDDNRSYYEALGVPESQVYSISYEKDAIEFISDKMKTKENKGKLILQVLSIDESGKLDVSVRQGLMEAREIFLVVTGSNKRDVIEKLYRENGKSSYEPADLKAHRMVNVILDKEAAAGLPEDVKEYFTARFV
>AP018587.1|BBD94655.1|1095169_1095349_+|hypothetical-protein
MAKEQESKLNYHEEENAMVTDLDDLKELGKEMEQISEENDEDKLNQSHDEDVRSDLQDK
>AP018587.1|BBD94656.1|1095584_1095983_+|membrane-protein
MLGKYWIHLMIATVIISLISVKGFPLALGALYLPLLFKIVQLQLNLSKGLVDDVSAQTFIKSNQSGVIISVICCLAITGILIYTLNDFYSRLTGILGFLVQISPITIVISAILFILLAIAIVQATKTKYKHS

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Crispr_ID: AP018587_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018587_6

1668982-1669075

Orphan

Consensus_repeat	Method
GCATAAGAGCCACTAACCGATGAATCGGTAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of AP018587_6

>merge|AP018587|6|1668982-1669075|CRISPRCasFinder
GCATAAGAGCCACTAACCGATGAATCGGTAAGCTTTTGGTAATACTTGAATCTACGCTTCATGCATAAGAGCCACTAACCGATGAATCGGTAAG

>AP018587|6|5|1668982-1669075|CRISPRCasFinder
GCATAAGAGCCACTAACCGATGAATCGGTAAG	CTTTTGGTAATACTTGAATCTACGCTTCAT
GCATAAGAGCCACTAACCGATGAATCGGTAAG

Protein	Signature genes	Signature genes Name	Protein_function
AP018587.1\|BBD95176.1\|1674468_1675296_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|314698
AP018587.1\|BBD95180.1\|1678782_1679493_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225099
AP018587.1\|BBD95163.1\|1661572_1661938_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226923
AP018587.1\|BBD95164.1\|1661939_1663484_-\|tRNA-2-methylthio-N6-dimethylallyladenosine-synthase	unknown	unknown	gnl\|CDD\|184624
AP018587.1\|BBD95168.1\|1665710_1667471_-\|2-oxoglutarate/2-oxoacid-ferredoxin-oxidoreductase-subunit-alpha	unknown	unknown	gnl\|CDD\|274738
AP018587.1\|BBD95165.1\|1663685_1663982_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223090
AP018587.1\|BBD95162.1\|1661054_1661549_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131412
AP018587.1\|BBD95171.1\|1669088_1670648_-\|putative-ribonuclease	unknown	unknown	gnl\|CDD\|237177
AP018587.1\|BBD95161.1\|1660844_1661015_-\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD95175.1\|1674057_1674450_-\|Cro/CI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224343
AP018587.1\|BBD95179.1\|1677470_1678745_-\|processing-proteinase-like-protein	unknown	unknown	gnl\|CDD\|223685
AP018587.1\|BBD95169.1\|1667605_1668400_-\|phosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|379099
AP018587.1\|BBD95173.1\|1672107_1673259_-\|competence-damage-inducible-protein	unknown	unknown	gnl\|CDD\|234789
AP018587.1\|BBD95167.1\|1664843_1665710_-\|2-oxoacid-ferredoxin-oxidoreductase,-beta-subunit-homologue	unknown	unknown	gnl\|CDD\|237006
AP018587.1\|BBD95174.1\|1673444_1674026_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|273139
AP018587.1\|BBD95178.1\|1676184_1677471_-\|processing-proteinase	unknown	unknown	gnl\|CDD\|223685
AP018587.1\|BBD95177.1\|1675480_1676185_-\|3-oxoacyl-(acyl-carrier-protein)-reductase	unknown	unknown	gnl\|CDD\|235506
AP018587.1\|BBD95172.1\|1670890_1671943_-\|recombination-protein-RecA	unknown	unknown	gnl\|CDD\|236476
AP018587.1\|BBD95166.1\|1664065_1664686_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368663
AP018587.1\|BBD95170.1\|1668562_1668778_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
AP018587.1\|BBD95176.1\|1674468_1675296_-\|hypothetical-protein	gnl\|CDD\|314698	pfam11868, DUF3388, Protein of unknown function (DUF3388). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 261 to 275 amino acids in length. This protein is found associated with pfam01842.	1.75557e-118
AP018587.1\|BBD95180.1\|1678782_1679493_-\|hypothetical-protein	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.62369e-48
AP018587.1\|BBD95163.1\|1661572_1661938_-\|hypothetical-protein	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	2.18006e-29
AP018587.1\|BBD95164.1\|1661939_1663484_-\|tRNA-2-methylthio-N6-dimethylallyladenosine-synthase	gnl\|CDD\|184624	PRK14327, PRK14327, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
AP018587.1\|BBD95168.1\|1665710_1667471_-\|2-oxoglutarate/2-oxoacid-ferredoxin-oxidoreductase-subunit-alpha	gnl\|CDD\|274738	TIGR03710, OAFO_sf, 2-oxoacid:acceptor oxidoreductase, alpha subunit. This family of proteins contains a C-terminal thiamine diphosphate (TPP) binding domain typical of flavodoxin/ferredoxin oxidoreductases (pfam01855) as well as an N-terminal domain similar to the gamma subunit of the same group of oxidoreductases (pfam01558). The genes represented by this model are always found in association with a neighboring gene for a beta subunit (TIGR02177) which also occurs in a 4-subunit (alpha/beta/gamma/ferredoxin) version of the system. This alpha/gamma plus beta structure was used to define the set of sequences to include in this model. This pair of genes is not consistantly observed in proximity to any electron acceptor genes, but is found next to putative ferredoxins or ferredoxin-domain proteins in Azoarcus sp. EbN1, Bradyrhizobium japonicum USDA 110, Frankia sp. CcI3, Rhodoferax ferrireducens DSM 15236, Rhodopseudomonas palustris BisB5, Os, Sphingomonas wittichii RW1 and Streptomyces clavuligerus. Other potential acceptors are also sporadically observed in close proximity including ferritin-like proteins, reberythrin, peroxiredoxin and a variety of other flavin and iron-sulfur cluster-containing proteins. The phylogenetic distribution of this family encompasses archaea, a number of deeply-branching bacterial clades and only a small number of firmicutes and proteobacteria. The enzyme from Sulfolobus has been characterized with respect to its substrate specificity, which is described as wide, encompassing various 2-oxoacids such as 2-oxoglutarate, 2-oxobutyrate and pyruvate. The enzyme from Hydrogenobacter thermophilus has been shown to have a high specificity towards 2-oxoglutarate and is one of the key enzymes in the reverse TCA cycle in this organism. Furthermore, considering its binding of coenzyme A, it can be reasonably inferred that the product of the reaction is succinyl-CoA. The genes for this enzyme in Prevotella intermedia 17, Persephonella marina EX-H1 and Picrophilus torridus DSM 9790 are in close proximity to a variety of TCA cycle genes. Persephonella marina and P. torridus are believed to encode complete TCA cycles, and none of these contains the lipoate-based 2-oxoglutarate dehydrogenase (E1/E2/E3) system. That system is presumed to be replaced by this one. In fact, the lipoate system is absent in most organisms possessing a member of this family, providing additional circumstantial evidence that many of these enzymes are capable of acting as 2-oxoglutarate dehydrogenases and.	0
AP018587.1\|BBD95165.1\|1663685_1663982_-\|hypothetical-protein	gnl\|CDD\|223090	COG0011, COG0011, Uncharacterized conserved protein [Function unknown].	1.35466e-26
AP018587.1\|BBD95162.1\|1661054_1661549_-\|hypothetical-protein	gnl\|CDD\|131412	TIGR02359, conserved_hypothetical_protein, energy coupling factor transporter S component ThiW. Levels of thiamine pyrophosphate (TPP) or thiamine regulate transcription or translation of a number of thiamine biosynthesis, salvage, or transport genes in a wide range of prokaryotes. The mechanism involves direct binding, with no protein involved,to a structural element called THI found in the untranslated upstream region of thiamine metabolism gene operons. This element is called a riboswitch and is seen also for other metabolites such as FMN and glycine. This protein family consists of proteins identified in operons controlled by the THI riboswitch and designated ThiW. The hydrophobic nature of this protein and reconstructed metabolic background suggests that this protein acts in transport of a thiazole precursor of thiamine. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	1.64209e-55
AP018587.1\|BBD95171.1\|1669088_1670648_-\|putative-ribonuclease	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
AP018587.1\|BBD95175.1\|1674057_1674450_-\|Cro/CI-family-transcriptional-regulator	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	2.48084e-32
AP018587.1\|BBD95179.1\|1677470_1678745_-\|processing-proteinase-like-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.67609e-68
AP018587.1\|BBD95169.1\|1667605_1668400_-\|phosphoesterase-family-protein	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.6995e-152
AP018587.1\|BBD95166.1\|1664065_1664686_-\|hypothetical-protein	gnl\|CDD\|368663	pfam05908, Gamma_PGA_hydro, Poly-gamma-glutamate hydrolase. This family consists of a number of bacterial and phage proteins that function as gamma-PGA hydrolase enzymes. Structurally the protein in this family adopted an open alpha/beta mixed core structure with a seven-stranded parallel/anti-parallel beta-sheet. This structure shows similarity to mammalian carboxypeptidase A and related enzymes.	2.4766e-73
AP018587.1\|BBD95167.1\|1664843_1665710_-\|2-oxoacid-ferredoxin-oxidoreductase,-beta-subunit-homologue	gnl\|CDD\|237006	PRK11867, PRK11867, 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed.	1.44852e-176
AP018587.1\|BBD95178.1\|1676184_1677471_-\|processing-proteinase	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.09223e-78
AP018587.1\|BBD95177.1\|1675480_1676185_-\|3-oxoacyl-(acyl-carrier-protein)-reductase	gnl\|CDD\|235506	PRK05565, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	3.09191e-58
AP018587.1\|BBD95172.1\|1670890_1671943_-\|recombination-protein-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
AP018587.1\|BBD95173.1\|1672107_1673259_-\|competence-damage-inducible-protein	gnl\|CDD\|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	7.38755e-133
AP018587.1\|BBD95174.1\|1673444_1674026_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	5.40773e-49

>AP018587.1|BBD95170.1|1668562_1668778_+|hypothetical-protein
MSINIDPEKFAELVVSSNPAKSDEPEDIAKESLTLYINAYRLAERYSNIATNCYDTAEIIREINDADLQLK
>AP018587.1|BBD95169.1|1667605_1668400_-|phosphoesterase-family-protein
MRILFIGDIVGKIGRNAISTYLPKIKQSYHPTVSIVNAENAAHGKGLTEKIYKQLLREGVDFMTMGNHTYGQREIYEFIDNANRMVRPANFPEEAPGVGMRFIQINEIKLAIINLQGRTFMQDIDDPFKKADQLIEEARQVTPYIFVDFHAETTSEKNAMGWYLDGRVSAVVGTHTHIQTSDNRVLPKGTGYITDVGMTGYYDGILGINRDEVIHRFITSLPQRHVVPDEGRSVLSGVIIDIDKEGKTTQIERILINDDHPFQG
>AP018587.1|BBD95168.1|1665710_1667471_-|2-oxoglutarate/2-oxoacid-ferredoxin-oxidoreductase-subunit-alpha
MKSQISWKVGGQQGEGIESTGEIFATAMNRKGYFLYGYRHFSSRIKGGHTNNKIRVSTSPVHAISDDLDILVAFDQETIELNHHEMRNDSIIIADSKAKPEKPEDCKAQLIDLPFTSTAKELGTALMKNMVAIGATSALMNLDTSTFEELITNMFSKKGEKVVEMNIQALNEGYRLMQAQLNAIEGDFELEENNENPHLYMVGNDAIGLGAISAGSKFMAAYPITPASEIMEYMIANLPKVGGTVIQTEDEIAAATMAIGSNYAGVRGFTASSGPGLSLMMESIGLSGMTETPFVIVNTQRGGPSTGLPTKQEQSDLMQMIYGTHGDIPKIVVAPTDAEDAFYLTVEAFNLAEEYQCPVIILSDLQLSLGKQTVKALDYNKIEIKRGELLQSDIEREEDDKSYFRRYALTGSGISPRPIPGVKGGIHHITGVEHNEEGKPSEAASNRQAQMEKRMRKTENLVIEKPVESNERHEHADILYIGFISSKGAIMEGSERLEEQGIKVNTLQIRQLHPFPKDTIQQSIDKASKVVVAEHNYQGQLSSILKMNIQLQDKLVNQTKYDGTPFLPHEIETKGLEIVKEIKELV
>AP018587.1|BBD95167.1|1664843_1665710_-|2-oxoacid-ferredoxin-oxidoreductase,-beta-subunit-homologue
MATFKDFRNNVKPNWCPGCGDFSVQAAIQKAAANVGLEPEEVAIITGIGCSGRLSGYIKSYGVHAIHGRALPLAQGVKMANKDLTVIASGGDGDGYAIGMGHTIHALRRNMNMTYIVMDNQIYGLTKGQTSPSSAVGFVTKTTPKGNIEKNVAPLELALSSGATFVAQGFSSDIKALTKLIEDAINHDGFSFVNVFSPCVTYNKVNTYDWFKEHLTNIDDIENYDTSDKQLAMKTVLEHESLVKGIVYQDTETPSYESQIDELEDEALAKKDIHISEETFNDLTAQFV
>AP018587.1|BBD95166.1|1664065_1664686_-|hypothetical-protein
MDKFKSMKILEKKTIENEDWEIEIEDKDSDVSILAIHGGGIEPGTTELAQVIAEKGGYNYFSFKGIRSKGNNELHVTSTHYDNQQALDLVKKSERAITVHGCKGEESVVYIGGDDYQLIDILSETLQDIGIKVEGAPHTMAGTQNRNITNQTKNDAGVQLELTSELRKSLFVNHKSSRKSRENRDNWGDLMYDFADATSKAIQQVQ
>AP018587.1|BBD95165.1|1663685_1663982_-|hypothetical-protein
MNDTLMSVQIVPRTPNNQDVIPYVDEAIKIIDESGLHYRVGPLETTVQGDMSECLILIQKLNERMVELECPSIISQVKFYHVPEGIEIETLTGKYDQE
>AP018587.1|BBD95164.1|1661939_1663484_-|tRNA-2-methylthio-N6-dimethylallyladenosine-synthase
MNEEQRKAGTINILAERDRKAEKDYSKYFEQVYQPPSLKEAKKRGKQEVQYNRDFHIDEKYKGMGNGRTFLIKTYGCQMNAHDTEVMAGILKALGYSATSDINQADVILINTCAIRENAENKVFSEIGNLKHLKKERPECLIGVCGCMSQEESVVNKILKSYQNVDMIFGTHNIHHLPEILEEAYLSKAMVVEVWSKEGDVIENLPKVREGSIKAWVNIMYGCDKFCTYCIVPFTRGKERSRRPEDIINEVRELAREGYQEITLLGQNVNSYGKDIEGLDYGLGDLLEDISKIDIPRVRFTTSHPWDFTDRMIEVIANGGNIVPHIHLPVQSGNNAVLKIMGRKYTRESYLDLVSRIKNAIPDIALTTDIIVGYPNETEEQFEETLSLYDEVEFEHAYTYLYSQRDGTPAAKMKDNVPTEVKKERLQRLNKKVGEYSQKAMSQYEGEIVTVLCEGSSKKDDTVLAGYTAKNKLVNFKAPKEMIGKLVDVKIDEAKQYSLNGTFVGEHQSEMVVQ
>AP018587.1|BBD95163.1|1661572_1661938_-|hypothetical-protein
MYSKEDILKHADTLANRINNLEIVKDYQTIEKQIHNNKTIENKMKNLKKQQKQSVNFQNYGKDNAFQQSENQIHHIEDEINQLPIVEEFRSAQYDANDLLQMMIKTMEDRLNEHNEREHKE
>AP018587.1|BBD95162.1|1661054_1661549_-|hypothetical-protein
MKVRKLTITAILIAINIVLSSLIVIPLGPIKAAPVQHFINVLCAVFVGPWYGLAQAFISSIFRVSFGTGSVFAFPGSMIGVFLSSLFYMYRKHIFMAAVGEVLGTGVIGSLMCIPLAWFMNFDNFLVRPLMIAFIVSSVIGSLISYILLIVLKRRGLLDKFNKK
>AP018587.1|BBD95161.1|1660844_1661015_-|hypothetical-protein
MGLKQFCLMLKRTFLYTFLVKRVVFIYVKMYELKAYVKKIKIRKIFINKGCENRNG
>AP018587.1|BBD95171.1|1669088_1670648_-|putative-ribonuclease
MNLLSLLLILLGIILGVVVGYVVARNLLHQKQVQSRQTAEDIVNHANKEADNIKKEKLLEAKEENQILREQAESELRERRGELQRQETRLLQKEENLDRKSDLLDKKDEILEQKESKLEERQQQVDAKESSVQTLIMKHEQELERISGLTQEEAVNEQLHRVEEELSQDIAILVKEKEKEAKEKVDKTAKELLATTVQRLAADHTTESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDDIIRDAGEQATFEINVHNMHPDLVKILGRLNYRTSYGQNVLKHSIEVAHLSGMLAAELDEDITLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLEALSESYDGVEKAFAIQAGREIRVVVSPEEIDDLKSYRLARDIKNQIEEELQYPGHIKVTVVRETRAVEYAK
>AP018587.1|BBD95172.1|1670890_1671943_-|recombination-protein-RecA
MDNERQKALDTVIKNMEKSFGKGAVMKLGDNKGRRVSSTSSGSVTVDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQKNGGVAAFIDAEHALDPVYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQDIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGERMGQGKENVKNYLKENPQIKEEIDRKLREKLGIFDGDVEETESEEDTPKTLFDEE
>AP018587.1|BBD95173.1|1672107_1673259_-|competence-damage-inducible-protein
MKISIIAVGSELLLGQIANTNGQYLSKLFNSIGKSVVEHTVIGDNPKRLEYVIKQGLERFDTLVLTGGLGPTKDDLTKHTVAKVLGRELVTDESSLSYIESYFREQGQEMTPNNKQQALVIEGSKVLPNKTGMAPGMLVEKEEKKVVLLPGPPKEMKPMAKNELLPYLLDDDRVIFSELLRFAGIGESKVETILMDLIDNQSNPTIAPLAGTHEVYIRLTANADTQTECEKLIQPIKKEILNRIGEYYFGSDDITIEESVMSKVKRTFAIYDGVTNGALYTRLKNVDTDNLLKGILPHSSVFVENDENIHAQLLSAAQYVRDLYQTELGIVLLNKDGEVYLAIYDGENLNIDTFKMAQSRNLLRNRSQNYAMIRLLKWFEQQE
>AP018587.1|BBD95174.1|1673444_1674026_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MNIPNQITVFRVILIPVFILFALVDFGFGQVSFLGGYHIRIEILISAIIFIIASLSDFADGYLARKWQLVTNMGKFLDPLADKLLVASALIVMVQLGFTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAIIWILLGDPLVHFIHFPLGVTLLYIGVFFTILSGIEYFYKGRDVFKQSK
>AP018587.1|BBD95175.1|1674057_1674450_-|Cro/CI-family-transcriptional-regulator
MKTVGEALKGRRERLGMTLNELEQRTQLKRQTLIHIENNDFDLLAKKDYTEGFIRKYANVVNIEPNQLIEAHRDEIPSNQHQMDQLMTTFSNGQVPSYRSKSKETIQLVMLIGMIVIVSLIIWILAVLIL
>AP018587.1|BBD95176.1|1674468_1675296_-|hypothetical-protein
MTVAERKEWYLEYEITINRAGLLGDISSLLGMLGISIVTINGVDQGKRGLLIKTDKLEKVERFEQIVKEINEIDITKLRIPELRDRLAVRHGRYIEQDADDKKTFKFEREDLGLLVDFLAELFKEEGHKLIGIRGMPRVGKTESIVAGSVCAHKRWLFISSTLIKQTVRSSLIKGEYESNHVYIIDGAVTARESNPKHQDLVREVMTLPSIKVVEHPDLFVEACNYSMDDFDYIIELRENENQEIHYDEMKKQTVQSKNSLEFGDPFGGGFGFFE
>AP018587.1|BBD95177.1|1675480_1676185_-|3-oxoacyl-(acyl-carrier-protein)-reductase
MKALVIGGSGSIGTAIVDRLLDEGYEVIIHYNTADLTSLKEKYKNNNVEFIQCDLAQDITLSEYFGHLNDIDCLIYTSGTALYGMLQDMSDEDIDYSYALHVRQFIRLSRYFVDTLRKSNNGRIIVISSIWGETGASMESIYSAMKSAQIGFVKALSQELALTSVTVNAIAPGFVSGNMSNAWSKEEMESIVVELPQNRMIEPYEVAHVCAYLCHPMSRSITGTVQKVNGGWYL
>AP018587.1|BBD95178.1|1676184_1677471_-|processing-proteinase
MKVHNYELIDEKVFEHELDNGLKLFIIPKPGFQKTFVTYTTQFGSLDNHFKPLGSNEFVKVPDGVAHFLEHKLFEKEEEDLFTAFAEENAQANAFTSFDRTSYLFSATNHLESNIKRLLTMVETPYFTEETVNKEKGIIAEEIKMYQEQPGYKLMFNTLRAMYSKHPIRVDIAGSVDSIYDITKDDLYLCYETFYHPSNMVLFVVGDVDPQSIVDLVDNHEKQRNKTNQPQIERAQIKEPEEVNTHTVTEKMKLQSPRLMLGFKNQPLNESSEKYVQRDLEMTFFYELIFGEETDFYQDLLNKDLIDETFGYQFVLEPSYSFSIITSATQHPDELKELLINELKKYRGHLADQEAFDLLKKQFIGEFISSLNSPEYIANQYAKLYFEGVSVFDMLEIVENITLESVNETSKLFLDFDHLVDSRLELKE
>AP018587.1|BBD95179.1|1677470_1678745_-|processing-proteinase-like-protein
METMNHDHSNIHINVLPTEKFKTTMVTFKFMAPLDYETITSRSILSKVLVRATQKWPNDKALNRHLSNLYGAYINSFVTKFKDKHVITISLEIVNERYLKDSTPLFEKGLEMLKELIWNPLIEDEQFNEKYVAQEKSLLTKKIEAMTDNKAQYSFLKLMNYMFKDEPYKYIATGQLEQIPQVTAQNLYDTYKSMIHNDECAIYVVGNVNEQETRNLIQNNFEIKPFELEKGSPLTQINHIGSPKVIIEEDEVDQAKLNLGYRFPTYYGKQNYYAFVVFNMMFGGDPSSVLFNEVREKQSLAYSIHSQIDGKNGFLFVLSGVSADKYERAKDTILEEFDKLKNGEFDETKLELAKKIIISHRHESTDRPKSMIELLHNQLLLDEYQSDEDFIKAINQVTKEDVIELANEAVLDTIYVLTKGGQSE
>AP018587.1|BBD95180.1|1678782_1679493_-|hypothetical-protein
MSEMNAIYRVKQYILNMIKNGELENGGKLPSNLSIARALNVKTDDVYDGIGELITEQIVTDNFEEGTSVKAQPPFFYPLDKLISISTMIEEAGYKAGIEYLNFDEQPATILDAEHLGIETKQPVTIIERLRTADHKPVVYCLDKIAKQYLTCLDYQKSNGSMLRAIKDATGHEVTHAEMDLEAISYEPHISEVLNASPHEGLMLLKVVHYDENGQPILYSLNYLKSSLVKFKVNKN

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Crispr_ID: AP018587_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

AP018587_7

2246933-2247033

Orphan

Consensus_repeat	Method
TTCTTATGCAATGGACACCAGTCCATTGTAATCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of AP018587_7

>merge|AP018587|7|2246933-2247033|CRISPRCasFinder
TTCTTATGCAATGGACACCAGTCCATTGTAATCCTAACTGAAAATGACTTATTTTTTCCTTAGTACTTCTTATGCAATGGACACCAGTCCATTGTAATCCT

>AP018587|7|6|2246933-2247033|CRISPRCasFinder
TTCTTATGCAATGGACACCAGTCCATTGTAATCCT	AACTGAAAATGACTTATTTTTTCCTTAGTAC
TTCTTATGCAATGGACACCAGTCCATTGTAATCCT

Protein	Signature genes	Signature genes Name	Protein_function
AP018587.1\|BBD95740.1\|2235521_2235800_+\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD95742.1\|2237591_2239142_-\|putative-di-and-tricarboxylate-transporter	unknown	unknown	gnl\|CDD\|279307
AP018587.1\|BBD95752.1\|2248439_2249009_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|129813
AP018587.1\|BBD95746.1\|2241887_2242331_+\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
AP018587.1\|BBD95757.1\|2251603_2252293_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368981
AP018587.1\|BBD95749.1\|2246029_2246902_+\|bacitracin-resistance-protein-(putative-undecaprenol-kinase)-homologue	unknown	unknown	gnl\|CDD\|234712
AP018587.1\|BBD95744.1\|2240422_2240719_-\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD95745.1\|2240736_2241663_-\|CobW/HypB/UreG,-nucleotide-binding-domain-protein	unknown	unknown	gnl\|CDD\|223597
AP018587.1\|BBD95756.1\|2251002_2251458_-\|acetyltransferase,-GNAT-family	unknown	unknown	gnl\|CDD\|366181
AP018587.1\|BBD95743.1\|2239345_2240287_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|180477
AP018587.1\|BBD95751.1\|2247979_2248429_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|178882
AP018587.1\|BBD95748.1\|2244174_2245803_-\|putative-ATP-binding-cassette,-subfamily-C,-bacterial-CydD	unknown	unknown	gnl\|CDD\|227321
AP018587.1\|BBD95741.1\|2235876_2237250_-\|putative-deoxyribodipyrimidine-photolyase	unknown	unknown	gnl\|CDD\|223492
AP018587.1\|BBD95753.1\|2249354_2249915_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379112
AP018587.1\|BBD95747.1\|2242474_2244172_-\|ABC-transporter-ATP-binding-cassette	unknown	unknown	gnl\|CDD\|227320
AP018587.1\|BBD95759.1\|2252976_2254185_-\|transporter,-major-facilitator-family-protein	unknown	unknown	gnl\|CDD\|341024
AP018587.1\|BBD95754.1\|2250036_2250333_-\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD95755.1\|2250489_2250945_-\|hypothetical-protein	unknown	unknown	unknown
AP018587.1\|BBD95750.1\|2247289_2247976_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173412
AP018587.1\|BBD95758.1\|2252481_2252970_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225395

Protein	Function_ID	Function_description	E-value
AP018587.1\|BBD95742.1\|2237591_2239142_-\|putative-di-and-tricarboxylate-transporter	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	8.45715e-93
AP018587.1\|BBD95752.1\|2248439_2249009_+\|hypothetical-protein	gnl\|CDD\|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	1.66802e-58
AP018587.1\|BBD95746.1\|2241887_2242331_+\|putative-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.24109e-19
AP018587.1\|BBD95757.1\|2251603_2252293_+\|hypothetical-protein	gnl\|CDD\|368981	pfam06570, DUF1129, Protein of unknown function (DUF1129). This family consists of several hypothetical bacterial proteins of unknown function.	0.000481187
AP018587.1\|BBD95747.1\|2242474_2244172_-\|ABC-transporter-ATP-binding-cassette	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	5.61739e-179
AP018587.1\|BBD95745.1\|2240736_2241663_-\|CobW/HypB/UreG,-nucleotide-binding-domain-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	8.37564e-71
AP018587.1\|BBD95756.1\|2251002_2251458_-\|acetyltransferase,-GNAT-family	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.67602e-11
AP018587.1\|BBD95743.1\|2239345_2240287_-\|malate-dehydrogenase	gnl\|CDD\|180477	PRK06223, PRK06223, malate dehydrogenase; Reviewed.	0
AP018587.1\|BBD95748.1\|2244174_2245803_-\|putative-ATP-binding-cassette,-subfamily-C,-bacterial-CydD	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	1.46323e-178
AP018587.1\|BBD95741.1\|2235876_2237250_-\|putative-deoxyribodipyrimidine-photolyase	gnl\|CDD\|223492	COG0415, PhrB, Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair].	1.16396e-149
AP018587.1\|BBD95753.1\|2249354_2249915_-\|hypothetical-protein	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	6.88174e-31
AP018587.1\|BBD95749.1\|2246029_2246902_+\|bacitracin-resistance-protein-(putative-undecaprenol-kinase)-homologue	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	7.35059e-101
AP018587.1\|BBD95751.1\|2247979_2248429_+\|hypothetical-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	6.87862e-73
AP018587.1\|BBD95759.1\|2252976_2254185_-\|transporter,-major-facilitator-family-protein	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.74373e-100
AP018587.1\|BBD95750.1\|2247289_2247976_+\|hypothetical-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	0.00293185
AP018587.1\|BBD95758.1\|2252481_2252970_-\|hypothetical-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	9.24315e-35

>AP018587.1|BBD95749.1|2246029_2246902_+|bacitracin-resistance-protein-(putative-undecaprenol-kinase)-homologue
MFLIELIKGIILGIVEGLTEFAPVSSTGHMILVDDMWLKSTKFLGEQSAFTFKVVIQLGSVFAAAWVFRDRFLEILHIGHHKPDNQASVQRRSQPKRLNLMHVLVGMIPAGILGFLFDDLIEKYLFSVPTVMIGLFLGAIYMILADKYSEKVQHPQTVDQINYFQAFVIGISQAIAMWPGFSRSGSTISTGVFMKLNHKAASDFTFIMSVPIMLAASGLSLLKHYEYIHLAHIPFYLLGFLAAFIVGLIAIKTFLHLISKVKLIPFAIYRIVLVVIIAILYFGFGIGKGI
>AP018587.1|BBD95748.1|2244174_2245803_-|putative-ATP-binding-cassette,-subfamily-C,-bacterial-CydD
MKKLTNLVFKYKIYPVLMCIVSIFLSITVVIQNISIARFLNHVLYNHKQPLIYLFIVILVVLIARATFNMLNQRIGDHMAYKVKTDLRRQVINKNSPRAIGEQMNILTESIDGIAPFFQSYLPQVFKSMMIPVAIIIAMCFVHLPTALIMMVTAPFIPMFYIIFGLKTRDESKDQMTYLNQFSQRFLNTAKGLITLKLLNRTKQTKAHLYEDSTRFRDLTMRILKSAFLSGLMLEFISMLGIGLVALEAALSLVVFNSISFVTAAIAIILAPEFYNAIKDLGQAFHTGKQSEGSSDVVFDFLEAEDQLPSPTPKVNNNQEPQIKVENVSYRYPGSEQYALRNINITIYQNDKIAIVGPSGAGKTTLAHILSQSVKPSDGEAIFNMEETRIGFLSQNPYIFTDTIKNNIAMYDYEISDEDIIQVLDEVGLKDKVLTLKDGIDTRIGEGGEMLSGGQMRRLELSRLLLMKPELVIFDEPATGLDIETERTIQAVLQDHFKETTMLIIAHRDTTINQAERRIYLENGQLIKDDATISVSQSEVNR
>AP018587.1|BBD95747.1|2242474_2244172_-|ABC-transporter-ATP-binding-cassette
MKPHIHFRIDKDLILAILVGVLGGLVALAMFFLSGYMVTQSALGAPLYALMVLVVSVKMFGFLRAITRYIERLLSHKTTFTMLRDVRVQFLEKLIPVVPDVYRKFNSSDLISRMISRVEALQNIYLRVYYPPVVIGLTAIVSIITFIFFTPMHALLIAVSMILTLWIVPWLSAKRARTLKQQVALQQSDFLQRFYDYKEGNEELKRFKQTHTFKTDVLNHLEHFDALQARERRFLSLYDYMLNLIAMISIFLSLVIGAQQVHAGHLDVVYLTSIVLMVLTLFEQAVPMSNVAYYKADTDQALAEINEVIDVSESRDDAHFESEKTKTELFEVEHVTFKYWNQQTPVLHDINLTIKKGEKVAIIGPSGSGKSTLLQVMLGLYQVEQGHVTLNGQVVTDIDNEEKYRYINGMLQSQHMFDGTVRDNLFSDKEDAELEGVLQSVGLGYLDLDRNVSLNGENLSGGEVQRLSLARLLLRDDARIWILDEPTTALDIDNTKKVMNLIEEASETLIVATHDLDVLSRFDKIVVMLDGEMKEIGSYDRLLNEDSYLHQMLELNNKTSPLVKD
>AP018587.1|BBD95746.1|2241887_2242331_+|putative-transcriptional-regulator
MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSEMIRPELSSASEKVATASSLSKEEVKELNRLLGKVIDAFTEAKEK
>AP018587.1|BBD95745.1|2240736_2241663_-|CobW/HypB/UreG,-nucleotide-binding-domain-protein
MRNNKDEKISISIISGFLGSGKTTLLTHYMSELLKIDEKISVIMNEIGSFDVDGNHLTDMVEVYSILNGCVCCDLKLDLVNQLEVLINEKDVNHIIIEATGIAHPIEIIMACQDPRIVQYVHQPQVIGVVDAERFLNREQYTESTKRLMEEQLEVSNVLIVNKIDLISEEEQQHLEEALNRINANVPHILTTYGKVDVSKLSQFRDEVVTQHTHSHHHGINSMQYTFSGPIDRQLFYQFILRLPDEVLRLKGYVQFRDHPNATYEFQYAYGLPDYGVIDKVLPLTIVIIGEQLDVNRLRNKLDMLQFS
>AP018587.1|BBD95744.1|2240422_2240719_-|hypothetical-protein
MNNEDKREKQIKFERNLITFPYLGFAIVVLLFNIFYPDIKVTMALFGIFFAYNLGMLFIAFIRHFKRTLILTLILTILSGAAFFTLLYVFGLRHDIFG
>AP018587.1|BBD95743.1|2239345_2240287_-|malate-dehydrogenase
MSTRRKISIIGAGNTGSTLAFILAQKELADIVMIDRPQSEGFVKGKALDILESGPIFGFDTQVQGSVQIEDIQDSDIVVMTAGIPRKPGMTRDDLVQTNEEIVYQTSRNIAKYAPQATIIVLTNPVDAMTYTALKASGFPKERVIGQSGVLDTARYQCFIAEELQVSVKDINGLVLGGHGDTMVPLVESTQVNGVPVKDLISKEVLERIVERTRKGGAEIVELLGKGSAYYAPATAIYEMIEAILKDQKRLLPSIAYLDGEYGFSDICLGVPTILGNHGIEKIVEVNLNDKEQEQLQHSAQSVENVKNALKNN
>AP018587.1|BBD95742.1|2237591_2239142_-|putative-di-and-tricarboxylate-transporter
MTKGNHEAQTQSQHSQSKKAYKPLWIIISFALLIGILLLPTPAGLPIMAKAALAILAFAVIMWVTEAVSYPVSAVLILGLIILLLGLSPVQNLSEKLGNPKSGDAILKGSELLGTNNALSHAFSGFSTSAVALVAAALFLAAAMQETNLHKRLALLVLSIVGNKTRNIVIGAILVSIVLAFFVPSATARAGAVVPILLGMIAAFNMSKESKLASLLIITSVQAVSIWNIGIKTAAAQNIVAINFINQNLGHDVSWGEWFLYAAPWSILMSIALYFIMVKVMPPERDAIEGGKELIKKELKDLGPVSAREWRLIVISILLLLFWSTEKVLHPIDSASITLIALGVMLMPKVGVITWKGVEKKIPWGTIIVFGVGISLGNVLLKTGAAQWLSDQTFGLMGLKGLPIIATIALITLFNILIHLGFASATSLSSALIPVFISLTSTLHLGDHAIGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKAGIPLTIVGYILVIIFSLTYWKWLGLV
>AP018587.1|BBD95741.1|2235876_2237250_-|putative-deoxyribodipyrimidine-photolyase
MKVGVILNRVFRLENNPLFEYISQNKEDIDQCYFIIPQEKFDKEAEMKANYYYGTLQKFVDTLHDYDIQPFLVDYDELTHFCKDKGISEVVLAGDIMSYHEEKYDILQQSASFKNEGISVVSVRANHYFKPSKTRNNKGEPYKVFTSFYKKWRPYLMKRSVFSYDIKDIAKMGVKSQQKVKGDYSQYGISEADAQYRWSDFLDKDIENYNTNREYLPEVLTSQLSIYLAYGVLDIIQIFNDLLENYDKDEQNYESFIRELIFREFYYVLMTYYPETAHQSFKDKYRDLQWSYNKENFNLWKEGKTGFLIIDAAMGELNTTGYMHNRMRMVVSQFLTKDLFIDWTWGEEYFRQKLIDYDSASNVHGWQWSASTGTDAVPYFRMFNPVRQSERFDKDALYIKKFVQTLNDIDAKYLHDTHKYERQIKEQGIELGKDYPKQIVNHSESRTHVMSEFKALE
>AP018587.1|BBD95740.1|2235521_2235800_+|hypothetical-protein
MIFNITLLIIILIVLQLIVGHFWHDIGFSYTQSILLMCLPLGIGLFLMQVFYYERRYPNWEVPLNIKLRLKYMYILTLLEYVAVYICLFILK
>AP018587.1|BBD95750.1|2247289_2247976_+|hypothetical-protein
MDNKKLIKTLINVLPIVIVPLVVERKRIKEHPDVRKATDATSKATSKATSAISNKASDVKEYVGDKKQEYDNKRELKKIAKENDPEYIEKKGEKLAKKNRKEADKMDKKLQKNIEKRHKEEDKQREENQKQRIKDMKKSQKYEEKVGLTPGKLDDKTEKKGEKLEKDNRKDVKKLDKKLQKNIEKRHKKEEKQREEAKKARKKEFKKYDDYVADSVVKQNKESDDSKA
>AP018587.1|BBD95751.1|2247979_2248429_+|hypothetical-protein
MMTKVIIDGDACPVVNSVIELTEGTGIFVTVLRSFSHFSHQIQPEHVKTVYVDDGPDAVDYKIVQIATSEDIVITQDYGLASLLIDKVRVVMHHKGSIYRSDNIQSLLDQRYLNAQIRKQGGRHKGPPPFTREDRLKFEQAFSKIIKQL
>AP018587.1|BBD95752.1|2248439_2249009_+|hypothetical-protein
MIRRIAVYCGASKGNDPSYVKEAYELGKYMAEQGYELVFGAGSVGIMGAIQDGVLDHGGKAIGVMPKMLDEREITSQKVSELILVDSMHERKNKMTELADAFVMAPGGAGSLEEFFEMYSWAQIGIHQKPIGVFNLNGFFEPLQALIEHMIKEGFIDKKYKKLAPLFDTKEALIEGLHNYKPLGVRTYD
>AP018587.1|BBD95753.1|2249354_2249915_-|hypothetical-protein
MGTYIETERLKLRDWEEKDLLPFQQMNANRQVRRYFPSLLSYRRSELDMRKMDEIIKEKGIGLFAVELKETGEWIGFIGVNYLPKESKYPFKELPLYEIGWRLIPEVWGNGIATEGAEAVMDYAMEKGITELYSFTSETNLPSRKVMEKIGMTFLDNFEFPDLSKYHPLKRHVRYYKELLPSQSEG
>AP018587.1|BBD95754.1|2250036_2250333_-|hypothetical-protein
MHEQDFNILEGKNLTLPELGRELENITGRTIVDSTSEIKRVIAHLPNFESDTDTFVATYRLNHQNDFIDATFTAPKEQRDRLKEIPVHVELISYISKA
>AP018587.1|BBD95755.1|2250489_2250945_-|hypothetical-protein
MKKWLTLLLASTLMLTACGKSNEKASLEKSINQLEKENKDLKKQKKDLQTQKDKLKDKQDRLQKDIDELPAEDTSKKSSKESKSNSSKENGSDEASSNDSKQSTETSKSDQSKASSKDAKQSSEQNQNVDKKTQDKASTNKNKDSKSTSNS
>AP018587.1|BBD95756.1|2251002_2251458_-|acetyltransferase,-GNAT-family
MKVITIEDKIWLNEIAKIHEHLISENESNYQVTTTSISLRYEMLKARLKYSQDAIFVSEQNTTLEGFIWAHYEPQMSVVQIEVLYVKPEYRKQSIATHLKNTIEEWAISIGATVIESTVNIDNHSMIQLNNHLGYHTTHLKMTKNLKGKNE
>AP018587.1|BBD95757.1|2251603_2252293_+|hypothetical-protein
MKSTAQLTKENNVKSLRLNNTDREIFENYMTYIRADLSVNPHDSELMLNRILKHLIRAEDKGMLAMEFFDHDPKAHAKKELKSLPNETIRNIFKYIYHNFIFLIGIFCFLKGFIGFFIGGDSNYLYLYTFPITVIVGLFIIFLFIWMSFRTVQLQCFSNSYWVWWLTYGVIALLLVALFYVFFIPQSFLAFGPYINVSNWTFIIIAIVITPIAFYINHHFYNKDANTRV
>AP018587.1|BBD95758.1|2252481_2252970_-|hypothetical-protein
MSVILWILIILMFILAFVGLVKPIIPSILVMWIGFLIYQFGFNDGHLSWVFYVAMIIFTVLILIADFMMNKYFVARFGGSKLGEYTALAGVILGCFVFPPFGIILVPLVAVFVVELLNGFDVKNALKVSLGSVVAFLASTVAQAIIMVIMVIWFFIDVFLFN
>AP018587.1|BBD95759.1|2252976_2254185_-|transporter,-major-facilitator-family-protein
MFTALLQIKNYKLFVVNMLLLGMGIAVTVPYLVLFATKDLGMTTTQYGLLLALAAISQFTVNSIIARFSDTHNVNRKILIISALFMGAVSFSIYFYVHQIWLFIVLYAIFQGLFAPAMPQLYASARESINISSSRDRAKFANTVLRSMFSLGFLFGPFIGAQLIELKGYSGLFGGTIAIILFTLILQIFFYQNLPAEQQISSQQHVEKAAPNMFKDKTLLVPFIAFILLHIGQWMYTMNMPLFVTDYLKEKEGYVGYLASLCAGLEVPFMVILGILSAKLPTRTLLIIGSIFGGAFYFSIGVFKNFYMMLAGQVCLAIFLAILLGLGISYFQDILPDFPGYASTLFANAMVIGQLCGNLLGGAMSHWVGLENVFFVSAGSIFVGMVLIFFTKDQKITEENME

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
AP018587_1	1.7\|327003\|20\|AP018587\|CRT	327003-327022	20	AP018587.1	326283-326302	1	0.95
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	AP018587.1	326295-326314	2	0.9
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	AP018587.1	326331-326350	2	0.9

1. spacer 1.7|327003|20|AP018587|CRT matches to position: 326283-326302, mismatch: 1, identity: 0.95

tagtgattccgactcagaca	CRISPR spacer
tagtgattcagactcagaca	Protospacer
********* **********

2. spacer 1.9|327129|20|AP018587|CRT matches to position: 326295-326314, mismatch: 2, identity: 0.9

ctcagacagcgactcagatt	CRISPR spacer
ctcagacagcgattccgatt	Protospacer
************.** ****

3. spacer 1.9|327129|20|AP018587|CRT matches to position: 326331-326350, mismatch: 2, identity: 0.9

ctcagacagcgactcagatt	CRISPR spacer
ctcagatagtgactcagatt	Protospacer
******.**.**********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21147-21166	0	1.0
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21345-21364	0	1.0
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15948-15967	0	1.0
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9705-9724	0	1.0
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9849-9868	0	1.0
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21147-21178	0	1.0
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15948-15979	0	1.0
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9705-9736	0	1.0
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9849-9880	0	1.0
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21219-21238	1	0.95
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21435-21454	1	0.95
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15840-15859	1	0.95
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9777-9796	1	0.95
AP018587_1	1.9\|327129\|20\|AP018587\|CRT	327129-327148	20	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9921-9940	1	0.95
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21345-21376	1	0.969
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21363-21394	1	0.969
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21435-21466	1	0.969
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15768-15799	1	0.969
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9993-10024	1	0.969
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21111-21142	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21273-21304	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21291-21322	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21309-21340	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21183-21214	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15750-15781	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15894-15925	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15912-15943	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15804-15835	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9669-9700	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9975-10006	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9741-9772	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9885-9916	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18587-18618	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16499-16530	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17177-17208	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17831-17862	2	0.938
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19313-19344	2	0.938
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15426-15451	3	0.885
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15444-15469	3	0.885
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15552-15577	3	0.885
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15678-15703	3	0.885
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21057-21082	3	0.885
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9615-9640	3	0.885
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21129-21160	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21327-21358	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21417-21448	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15606-15637	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15732-15763	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15930-15961	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9687-9718	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9831-9862	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9597-9628	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17021-17052	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	20033-20064	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16481-16512	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16661-16692	3	0.906
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17159-17190	3	0.906
AP018587_1	1.6\|326931\|32\|AP018587\|CRT	326931-326962	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15426-15457	4	0.875
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16487-16512	4	0.846
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16505-16530	4	0.846
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17165-17190	4	0.846
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17183-17208	4	0.846
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18137-18162	4	0.846
AP018587_1	1.8\|327063\|26\|AP018587\|CRT	327063-327088	26	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19619-19644	4	0.846
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18197-18228	4	0.875
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19679-19710	4	0.875
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	155979-156010	4	0.875
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	CP052500	Klebsiella pneumoniae strain B17KP0021 plasmid unnamed	2208-2239	4	0.875
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	CP052500	Klebsiella pneumoniae strain B17KP0021 plasmid unnamed	2580-2611	4	0.875
AP018587_1	1.5\|326859\|32\|AP018587\|CRT	326859-326890	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15426-15457	5	0.844
AP018587_1	1.6\|326931\|32\|AP018587\|CRT	326931-326962	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15534-15565	5	0.844
AP018587_1	1.6\|326931\|32\|AP018587\|CRT	326931-326962	32	NZ_CP047808	Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence	15660-15691	5	0.844
AP018587_1	1.6\|326931\|32\|AP018587\|CRT	326931-326962	32	NZ_CP023562	Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence	21039-21070	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18569-18600	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18131-18162	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19013-19044	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19613-19644	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16703-16734	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18941-18972	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16871-16902	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17873-17904	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17945-17976	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18149-18180	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18353-18384	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19073-19104	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19355-19386	5	0.844
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19427-19458	5	0.844
AP018587_1	1.6\|326931\|32\|AP018587\|CRT	326931-326962	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9579-9610	6	0.812
AP018587_1	1.6\|326931\|32\|AP018587\|CRT	326931-326962	32	NZ_LT009691	Staphylococcus aureus strain NZAK3 plasmid 2	9597-9628	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16619-16650	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16931-16962	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17003-17034	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18287-18318	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17849-17880	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19331-19362	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16517-16548	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16973-17004	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17195-17226	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17537-17568	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18329-18360	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17273-17304	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18407-18438	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19127-19158	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19853-19884	6	0.812
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17903-17934	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19385-19416	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16679-16710	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16847-16878	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17297-17328	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17669-17700	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17969-18000	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18173-18204	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18431-18462	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18917-18948	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19151-19182	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19451-19482	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16811-16842	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17645-17676	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18101-18132	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19583-19614	7	0.781
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19805-19836	7	0.781
AP018587_4	4.1\|638514\|33\|AP018587\|CRISPRCasFinder	638514-638546	33	NZ_CP023514	Enterococcus sp. FDAARGOS_375 plasmid unnamed1, complete sequence	110127-110159	7	0.788
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16097-16128	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16229-16260	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16361-16392	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16637-16668	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	16949-16980	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17039-17070	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17387-17418	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	17807-17838	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18305-18336	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18701-18732	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	18893-18924	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19049-19080	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19289-19320	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19655-19686	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NZ_CP035292	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence	19979-20010	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	NC_048174	Shigella phage HRP29, complete genome	892-923	8	0.75
AP018587_1	1.10\|327189\|32\|AP018587\|CRT	327189-327220	32	MK562503	Shigella phage Buco, complete genome	892-923	8	0.75
AP018587_6	6.1\|1669014\|30\|AP018587\|CRISPRCasFinder	1669014-1669043	30	MT822287	Erwinia phage pEp_SNUABM_11, complete genome	472-501	8	0.733

1. spacer 1.9|327129|20|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 0, identity: 1.0

ctcagacagcgactcagatt	CRISPR spacer
ctcagacagcgactcagatt	Protospacer
********************

2. spacer 1.9|327129|20|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 0, identity: 1.0

ctcagacagcgactcagatt	CRISPR spacer
ctcagacagcgactcagatt	Protospacer
********************

3. spacer 1.9|327129|20|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

ctcagacagcgactcagatt	CRISPR spacer
ctcagacagcgactcagatt	Protospacer
********************

4. spacer 1.9|327129|20|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 0, identity: 1.0

ctcagacagcgactcagatt	CRISPR spacer
ctcagacagcgactcagatt	Protospacer
********************

5. spacer 1.9|327129|20|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 0, identity: 1.0

ctcagacagcgactcagatt	CRISPR spacer
ctcagacagcgactcagatt	Protospacer
********************

6. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 0, identity: 1.0

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagatt	Protospacer
********************************

7. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagatt	Protospacer
********************************

8. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 0, identity: 1.0

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagatt	Protospacer
********************************

9. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 0, identity: 1.0

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagatt	Protospacer
********************************

10. spacer 1.9|327129|20|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 1, identity: 0.95

ctcagacagcgactcagatt	CRISPR spacer
ttcagacagcgactcagatt	Protospacer
.*******************

11. spacer 1.9|327129|20|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 1, identity: 0.95

ctcagacagcgactcagatt	CRISPR spacer
ttcagacagcgactcagatt	Protospacer
.*******************

12. spacer 1.9|327129|20|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.95

ctcagacagcgactcagatt	CRISPR spacer
ttcagacagcgactcagatt	Protospacer
.*******************

13. spacer 1.9|327129|20|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 1, identity: 0.95

ctcagacagcgactcagatt	CRISPR spacer
ttcagacagcgactcagatt	Protospacer
.*******************

14. spacer 1.9|327129|20|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 1, identity: 0.95

ctcagacagcgactcagatt	CRISPR spacer
ttcagacagcgactcagatt	Protospacer
.*******************

15. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 1, identity: 0.969

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactcagatt	Protospacer
.*******************************

16. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 1, identity: 0.969

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagact	Protospacer
******************************.*

17. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 1, identity: 0.969

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagattcagacagcgactcagatt	Protospacer
************.*******************

18. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.969

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagact	Protospacer
******************************.*

19. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 1, identity: 0.969

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgactcagact	Protospacer
******************************.*

20. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactccgatt	Protospacer
.************************** ****

21. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgattcagatt	Protospacer
.***********************.*******

22. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactcagact	Protospacer
.*****************************.*

23. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactcagact	Protospacer
.*****************************.*

24. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagacagcgattcagatt	Protospacer
******.*****************.*******

25. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactcagact	Protospacer
.*****************************.*

26. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgattcagatt	Protospacer
.***********************.*******

27. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactcagact	Protospacer
.*****************************.*

28. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagacagcgattcagatt	Protospacer
******.*****************.*******

29. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactccgatt	Protospacer
.************************** ****

30. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactccgatt	Protospacer
.************************** ****

31. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagacagcgattcagatt	Protospacer
******.*****************.*******

32. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagacagcgattcagatt	Protospacer
******.*****************.*******

33. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgactctgatt	Protospacer
.************************** ****

34. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagatagcgactcagact	Protospacer
******************.***********.*

35. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagatagcgactcagact	Protospacer
******************.***********.*

36. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgactcagact	Protospacer
********* ********************.*

37. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.938

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgactcagact	Protospacer
********* ********************.*

38. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.885

ttccgactcagatagtgactcagatt	CRISPR spacer
ctcagactcagatagtgattcagatt	Protospacer
.** **************.*******

39. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.885

ttccgactcagatagtgactcagatt	CRISPR spacer
ttcagactcagatagcgactcagact	Protospacer
*** ***********.********.*

40. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.885

ttccgactcagatagtgactcagatt	CRISPR spacer
ttcagactcagatagcgactcagact	Protospacer
*** ***********.********.*

41. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.885

ttccgactcagatagtgactcagatt	CRISPR spacer
ttcagactcagatagcgactcagact	Protospacer
*** ***********.********.*

42. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 3, identity: 0.885

ttccgactcagatagtgactcagatt	CRISPR spacer
ttcagactcagatagcgactcagact	Protospacer
*** ***********.********.*

43. spacer 1.8|327063|26|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 3, identity: 0.885

ttccgactcagatagtgactcagatt	CRISPR spacer
ttcagactcagatagcgactcagact	Protospacer
*** ***********.********.*

44. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagattcagacagcgactcagact	Protospacer
.***********.*****************.*

45. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagattcagacagcgactcagact	Protospacer
.***********.*****************.*

46. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagattcagatagcgactcagatt	Protospacer
.***********.*****.*************

47. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagatagcgactccgatt	Protospacer
.*****************.******** ****

48. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagatagcgactccgatt	Protospacer
.*****************.******** ****

49. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagattcagacagcgactcagact	Protospacer
.***********.*****************.*

50. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagattcagacagcgactcagact	Protospacer
.***********.*****************.*

51. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagattcagacagcgattcagatt	Protospacer
.***********.***********.*******

52. spacer 1.10|327189|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagatagcgattcagact	Protospacer
******************.*****.*****.*

53. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgactcagacagcgactctgatt	Protospacer
.******** ***************** ****

54. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgattcagactcagacagcgactctgatt	Protospacer
.*****.******************** ****

55. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagatagcgactcagact	Protospacer
********* ********.***********.*

56. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgactctgact	Protospacer
********* ***************** **.*

57. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.906

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagatagcgactcagact	Protospacer
********* ********.***********.*

58. spacer 1.6|326931|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.875

ttgtggctcagactcagattgtgattcagatt	CRISPR spacer
tagcgactcagactcagatagtgattcagatt	Protospacer
* *.*.************* ************

59. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccgactcagatagtgactcagatt	CRISPR spacer
ctctgactcagatagcgactcagact	Protospacer
.**.***********.********.*

60. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccgactcagatagtgactcagatt	CRISPR spacer
ctcagactcagatagcgactcagact	Protospacer
.** ***********.********.*

61. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccgactcagatagtgactcagatt	CRISPR spacer
ctctgactcagatagcgactcagact	Protospacer
.**.***********.********.*

62. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccgactcagatagtgactcagatt	CRISPR spacer
ctcagactcagatagcgactcagact	Protospacer
.** ***********.********.*

63. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccgactcagatagtgactcagatt	CRISPR spacer
ctcagactcagatagcgactcagact	Protospacer
.** ***********.********.*

64. spacer 1.8|327063|26|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccgactcagatagtgactcagatt	CRISPR spacer
ctcagactcagatagcgactcagact	Protospacer
.** ***********.********.*

65. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.875

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgacagcgact	Protospacer
*************************   **.*

66. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.875

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagacagcgacagcgact	Protospacer
*************************   **.*

67. spacer 1.10|327189|32|AP018587|CRT matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 4, identity: 0.875

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcggactcagacagcgactcggact	Protospacer
.********.*****************.**.*

68. spacer 1.10|327189|32|AP018587|CRT matches to CP052500 (Klebsiella pneumoniae strain B17KP0021 plasmid unnamed) position: , mismatch: 4, identity: 0.875

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactccgacagcgactcggact	Protospacer
.************** ***********.**.*

69. spacer 1.10|327189|32|AP018587|CRT matches to CP052500 (Klebsiella pneumoniae strain B17KP0021 plasmid unnamed) position: , mismatch: 4, identity: 0.875

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactccgacagcgactctgact	Protospacer
.************** *********** **.*

70. spacer 1.5|326859|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

ttgtggctccgactcagattgtgattcagatt	CRISPR spacer
tagcgactcagactcagatagtgattcagatt	Protospacer
* *.*.*** ********* ************

71. spacer 1.6|326931|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

ttgtggctcagactcagattgtgattcagatt	CRISPR spacer
tagcgactcagactcagatagtgattccgatt	Protospacer
* *.*.************* ******* ****

72. spacer 1.6|326931|32|AP018587|CRT matches to NZ_CP047808 (Staphylococcus aureus strain UP_1612 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

ttgtggctcagactcagattgtgattcagatt	CRISPR spacer
tagcgactcagactcagatagtgattccgatt	Protospacer
* *.*.************* ******* ****

73. spacer 1.6|326931|32|AP018587|CRT matches to NZ_CP023562 (Staphylococcus aureus strain TF3198 plasmid pTF3198, complete sequence) position: , mismatch: 5, identity: 0.844

ttgtggctcagactcagattgtgattcagatt	CRISPR spacer
tagcgactcagactcagatagtgattccgatt	Protospacer
* *.*.************* ******* ****

74. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ctctgactcagactcagacagcgactcagact	Protospacer
.  .**************************.*

75. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ttcagactcagactcagatagcgactcagact	Protospacer
*   **************.***********.*

76. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ttcagactcagactcagatagcgactctgatt	Protospacer
*   **************.******** ****

77. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ttcagactcagactcagatagcgactcagact	Protospacer
*   **************.***********.*

78. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgacagcgact	Protospacer
********* ***************   **.*

79. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgacagcgact	Protospacer
********* ***************   **.*

80. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

81. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

82. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

83. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagatagcgatagcgatt	Protospacer
******************.*****.   ****

84. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

85. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

86. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

87. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgatt	Protospacer
********* **************.   ****

88. spacer 1.6|326931|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 6, identity: 0.812

ttgtggctcagactcagattgtgattcagatt	CRISPR spacer
tagcgattcagactcagatagtgattccgatt	Protospacer
* *.*..************ ******* ****

89. spacer 1.6|326931|32|AP018587|CRT matches to NZ_LT009691 (Staphylococcus aureus strain NZAK3 plasmid 2) position: , mismatch: 6, identity: 0.812

ttgtggctcagactcagattgtgattcagatt	CRISPR spacer
tagcgactcagactcagatagcgattcagact	Protospacer
* *.*.************* *.********.*

90. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ctctgattcagactcagacagcgactctgatt	Protospacer
.  .**.******************** ****

91. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ctctgattcagactcagacagcgactctgatt	Protospacer
.  .**.******************** ****

92. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ctcagactcagactcagacagcgactctgact	Protospacer
.   *********************** **.*

93. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ctctgattcagactcagacagcgactctgatt	Protospacer
.  .**.******************** ****

94. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgatagcgact	Protospacer
.***********************.   **.*

95. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactcagactcagacagcgatagcgact	Protospacer
.***********************.   **.*

96. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagatagcgatagcgact	Protospacer
******************.*****.   **.*

97. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgact	Protospacer
********* **************.   **.*

98. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactcagactcagatagcgatagcgact	Protospacer
******************.*****.   **.*

99. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgactcagacagcgacagcgact	Protospacer
.******** ***************   **.*

100. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgactcagacagcgatagcgact	Protospacer
********* **************.   **.*

101. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgattcagacagcgatagcgatt	Protospacer
********* **.***********.   ****

102. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgattcagacagcgatagcgatt	Protospacer
********* **.***********.   ****

103. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgattcagacagcgatagcgatt	Protospacer
********* **.***********.   ****

104. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgattcagacagcgatagcgatt	Protospacer
********* **.***********.   ****

105. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ttcagactcagactcagatagcgactctgacg	Protospacer
*   **************.******** **.

106. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
ttcagactcagactcagatagcgactctgacg	Protospacer
*   **************.******** **.

107. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgactcagacagcgatagcgact	Protospacer
.******** **************.   **.*

108. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgattcagacagcgatagcgact	Protospacer
********* **.***********.   **.*

109. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

110. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

111. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

112. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

113. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

114. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgactctgattcagacagcgatagcgact	Protospacer
********* **.***********.   **.*

115. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

116. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
tagcgattcagactcagatagcgatagcgact	Protospacer
******.***********.*****.   **.*

117. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgatt	Protospacer
.******** **.***********.   ****

118. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgatt	Protospacer
.******** **.***********.   ****

119. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagtgattcagactcagacagcgatagcgatt	Protospacer
.**.**.*****************.   ****

120. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagtgattcagactcagacagcgatagcgatt	Protospacer
.**.**.*****************.   ****

121. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgatt	Protospacer
.******** **.***********.   ****

122. spacer 4.1|638514|33|AP018587|CRISPRCasFinder matches to NZ_CP023514 (Enterococcus sp. FDAARGOS_375 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

tgcatttgtccaaagacaaatgtaaacatatgg-	CRISPR spacer
tatttttgtccaaagataaatgtaatca-atgct	Protospacer
*.. ************.******** ** ***

123. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

124. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

125. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

126. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

127. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

128. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

129. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

130. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

131. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

132. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

133. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

134. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

135. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

136. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgattcagactcagatagcgatagcgact	Protospacer
.*****.***********.*****.   **.*

137. spacer 1.10|327189|32|AP018587|CRT matches to NZ_CP035292 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgactcagactcagacagcgactcagatt	CRISPR spacer
cagcgactctgattcagacagcgatagcgact	Protospacer
.******** **.***********.   **.*

138. spacer 1.10|327189|32|AP018587|CRT matches to NC_048174 (Shigella phage HRP29, complete genome) position: , mismatch: 8, identity: 0.75

-tagcgactcagactcagacagcgactcagatt	CRISPR spacer
gttgt-actcagcctcagacagcgcctcagcgc	Protospacer
 * *. ****** *********** *****  .

139. spacer 1.10|327189|32|AP018587|CRT matches to MK562503 (Shigella phage Buco, complete genome) position: , mismatch: 8, identity: 0.75

-tagcgactcagactcagacagcgactcagatt	CRISPR spacer
gttgt-actcagcctcagacagcgcctcagcgc	Protospacer
 * *. ****** *********** *****  .

140. spacer 6.1|1669014|30|AP018587|CRISPRCasFinder matches to MT822287 (Erwinia phage pEp_SNUABM_11, complete genome) position: , mismatch: 8, identity: 0.733

cttttggtaatacttgaatctacgcttcat	CRISPR spacer
cgtccattaatacttgaatctccgcttcgg	Protospacer
* *... ************** ******.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

564238 : 580518

Bacillus_phage(33.33%)

protease,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD94124.1\|564238_565021_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
BBD94125.1\|565040_565832_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
BBD94126.1\|565977_566640_+	putative ABC transport system ATP-binding protein	W8CYL7	Bacillus_phage	2.5e-18	37.1
BBD94127.1\|566632_567409_+	putative ABC transport system permease protein	NA	NA	NA	NA
BBD94128.1\|567477_568947_-	ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein	NA	NA	NA	NA
BBD94129.1\|568939_569611_-	response regulator	NA	NA	NA	NA
BBD94130.1\|569758_569992_+	hypothetical protein	NA	NA	NA	NA
BBD94131.1\|570127_571294_+	hypothetical protein	NA	NA	NA	NA
BBD94132.1\|571336_572695_-	putative para-nitrobenzyl esterase	NA	NA	NA	NA
BBD94133.1\|572780_574460_-	putative Amino acid transporter	NA	NA	NA	NA
BBD94134.1\|574644_575244_+	hypothetical protein	NA	NA	NA	NA
BBD94135.1\|575394_576447_-	zinc-dependent dehydrogenase	A0A2K9L7I1	Tupanvirus	1.4e-10	21.2
BBD94136.1\|576959_578231_+\|holin	choline transport ATP-binding protein	Q6GZ03	Mycoplasma_phage	8.9e-20	51.6
BBD94137.1\|578230_578866_+\|holin	probable glycine betaine/carnitine/choline ABC transporter	NA	NA	NA	NA
BBD94138.1\|578887_579832_+\|holin	glycine betaine/carnitine/choline ABC transporter	NA	NA	NA	NA
BBD94139.1\|579831_580518_+\|holin	probable glycine betaine/carnitine/choline ABC transporter	NA	NA	NA	NA

DBSCAN-SWA_2

970528 : 987092

uncultured_Caudovirales_phage(68.42%)

terminase,integrase

attL 963509:963526|attR 984638:984655

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
963509:963526	attL	NA	NA	NA	NA
BBD94533.1\|970528_970813_+	co-chaperonin GroES	A0A221S4A5	uncultured_virus	8.9e-13	36.2
BBD94534.1\|970882_972502_+	60 kDa chaperonin	A0A240F779	uncultured_virus	7.6e-157	54.4
BBD94535.1\|972570_973746_-\|integrase	integrase	A0A2H4JBC4	uncultured_Caudovirales_phage	8.3e-214	95.4
BBD94536.1\|973754_974339_-	putative phage repressor protein	A0A1W6JPB6	Staphylococcus_phage	2.2e-13	29.4
BBD94537.1\|974435_974654_+	transcriptional regulator, Cro/CI family	NA	NA	NA	NA
BBD94538.1\|974657_974972_+	hypothetical protein	A0A2H4JHK0	uncultured_Caudovirales_phage	9.5e-48	93.3
BBD94539.1\|974984_975185_+	hypothetical protein	A0A2H4JD47	uncultured_Caudovirales_phage	2.4e-28	93.9
BBD94540.1\|975188_975593_+	hypothetical protein	A0A2H4JBF1	uncultured_Caudovirales_phage	3.3e-61	88.1
BBD94541.1\|975597_975804_+	hypothetical protein	A0A2H4JHP9	uncultured_Caudovirales_phage	1.3e-29	100.0
BBD94542.1\|975818_976127_+	hypothetical protein	A0A2H4JB50	uncultured_Caudovirales_phage	1.3e-38	83.3
BBD94543.1\|976219_977092_+	putative phage primase	A0A2H4JEH3	uncultured_Caudovirales_phage	2.0e-124	75.1
BBD94544.1\|977104_978808_+	hypothetical protein	Q4ZE73	Staphylococcus_phage	1.4e-273	82.9
BBD94545.1\|979118_979637_+	hypothetical protein	NA	NA	NA	NA
BBD94546.1\|979641_980286_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	8.7e-80	67.6
BBD94547.1\|980648_980981_+	hypothetical protein	A0A2H4JHK4	uncultured_Caudovirales_phage	4.2e-54	99.1
BBD94548.1\|981059_981647_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	6.7e-55	94.2
BBD94549.1\|981646_981856_+	hypothetical protein	A0A2H4JHW4	uncultured_Caudovirales_phage	6.1e-11	52.2
BBD94550.1\|981910_982360_+	hypothetical protein	A0A2H4JBD6	uncultured_Caudovirales_phage	1.1e-60	83.7
BBD94551.1\|982356_982698_+	hypothetical protein	NA	NA	NA	NA
BBD94552.1\|982699_983272_+\|terminase	phage terminase small subunit	A0A2H4JBF3	uncultured_Caudovirales_phage	1.4e-102	100.0
BBD94553.1\|983277_983547_+	hypothetical protein	A0A2H4JBE4	uncultured_Caudovirales_phage	1.7e-45	100.0
BBD94554.1\|984012_984393_-	beta-lactamase repressor BlaI	NA	NA	NA	NA
BBD94555.1\|984382_986140_-	beta-lactamase regulatory sensor-transducer BlaR1	NA	NA	NA	NA
984638:984655	attR	NA	NA	NA	NA
BBD94556.1\|986246_987092_+	beta-lactamase	A0A1B0VBP7	Salmonella_phage	3.4e-31	34.3

DBSCAN-SWA_3

1121031 : 1162060

Staphylococcus_phage(96.3%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD94679.1\|1121031_1122441_+	2-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	7.7e-174	63.0
BBD94680.1\|1122430_1123432_+	O-succinylbenzoic acid synthetase	A0A2H4PQM0	Staphylococcus_phage	3.1e-100	53.3
BBD94681.1\|1123428_1123680_-	membrane protein	A0A2H4PQM5	Staphylococcus_phage	2.7e-37	88.0
BBD94682.1\|1123748_1124222_+	MutT/nudix family protein	A0A2H4PQM4	Staphylococcus_phage	1.6e-46	57.1
BBD94683.1\|1124202_1124985_+	hypothetical protein	A0A2H4PQM6	Staphylococcus_phage	4.5e-107	74.1
BBD94684.1\|1125063_1126656_-	phosphoenolpyruvate carboxykinase [ATP]	A0A2H4PQN1	Staphylococcus_phage	1.8e-280	88.3
BBD94685.1\|1126767_1126965_+	hypothetical protein	NA	NA	NA	NA
BBD94686.1\|1127031_1128228_+	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	7.2e-197	87.2
BBD94687.1\|1128331_1129243_+	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	2.4e-107	80.9
BBD94688.1\|1129398_1130235_+	plant metabolite dehydrogenase homolog	A0A2H4PQR8	Staphylococcus_phage	4.5e-113	71.1
BBD94689.1\|1130511_1130865_-	CrcB-like protein	A0A2H4PQQ7	Staphylococcus_phage	9.7e-09	35.0
BBD94690.1\|1130861_1131227_-	putative camphor resistance protein CrcB	A0A2H4PQR0	Staphylococcus_phage	9.3e-39	66.1
BBD94691.1\|1131324_1131633_-	hypothetical protein	NA	NA	NA	NA
BBD94692.1\|1131926_1132640_+	putative transaldolase	H8ZNI7	Synechococcus_phage	3.2e-19	37.7
BBD94693.1\|1132798_1133242_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	8.7e-23	51.0
BBD94694.1\|1133228_1133672_-	hypothetical protein	NA	NA	NA	NA
BBD94695.1\|1133685_1134162_-	RNA polymerase sigma factor, sigma-70 family	A0A2H4PQT5	Staphylococcus_phage	2.2e-32	46.8
BBD94696.1\|1134370_1134589_+	hypothetical protein	NA	NA	NA	NA
BBD94697.1\|1134903_1135755_+	putative N-acetylmuramoyl-L-alanine amidase	A0A1W6JNR1	Staphylococcus_phage	4.9e-30	46.4
BBD94698.1\|1136072_1137563_+	hypothetical protein	A0A2H4PQX2	Staphylococcus_phage	4.7e-20	91.1
BBD94699.1\|1137987_1139031_+	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	5.8e-134	65.9
BBD94700.1\|1139037_1139670_+	riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	1.5e-89	79.5
BBD94701.1\|1139681_1140863_+	riboflavin biosynthesis protein RibA	A0A2H4PQS2	Staphylococcus_phage	3.9e-179	77.9
BBD94702.1\|1140906_1141365_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.9e-60	84.9
BBD94703.1\|1141437_1142439_-	proline dehydrohenase homolog	A0A2H4PQT6	Staphylococcus_phage	2.0e-139	73.9
BBD94704.1\|1142686_1143514_+	lysophospholipase homolog	NA	NA	NA	NA
BBD94705.1\|1144077_1144479_+	HTH-type transcriptional regulator Rot	NA	NA	NA	NA
BBD94706.1\|1144552_1145116_-	rRNA methyltransferase	A0A2H4PQV0	Staphylococcus_phage	2.3e-60	62.2
BBD94707.1\|1145112_1146072_-	putative Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	4.3e-67	85.4
BBD94708.1\|1146178_1147399_+	multidrug resistance protein homolog	A0A2H4PQR6	Staphylococcus_phage	3.9e-182	83.5
BBD94709.1\|1147695_1150110_+\|tRNA	leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	88.8
BBD94710.1\|1150133_1150445_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	3.5e-34	68.9
BBD94711.1\|1150948_1162060_+	SesA-like protein	A0A2H4PQU6	Staphylococcus_phage	9.1e-52	31.9

DBSCAN-SWA_4

1286497 : 1295638

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD94821.1\|1286497_1287502_+	Holliday junction ATP-dependent DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
BBD94822.1\|1287503_1288529_+\|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
BBD94823.1\|1288549_1289689_+\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.1e-85	45.0
BBD94824.1\|1289704_1289968_+	preprotein translocase, YajC subunit	A0A1B1IVR5	uncultured_Mediterranean_phage	9.8e-06	42.6
BBD94825.1\|1290399_1292691_+	protein-export membrane protein SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.7e-32	34.8
BBD94826.1\|1292827_1295101_+	putative single-strand DNA-specific exonuclease	A7KV88	Bacillus_phage	1.8e-63	28.3
BBD94827.1\|1295119_1295638_+	adenine phosphoribosyl transferase	A0A1V0SKE5	Klosneuvirus	1.1e-29	45.5

DBSCAN-SWA_5

1424037 : 1433873

Bacillus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD94962.1\|1424037_1424925_+	tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	2.7e-39	32.1
BBD94963.1\|1424977_1425511_-	tetratricopeptide repeat protein	NA	NA	NA	NA
BBD94964.1\|1425608_1426340_+	putative segregation and condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	7.9e-05	27.8
BBD94965.1\|1426332_1426875_+	segregation and condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	1.2e-10	33.8
BBD94966.1\|1426867_1427605_+	pseudouridine synthase	NA	NA	NA	NA
BBD94967.1\|1427740_1428466_+	respiratory response protein SrrA	W8CYM9	Bacillus_phage	4.6e-45	40.9
BBD94968.1\|1428446_1430213_+	respiratory response protein SrrB	W8CYF6	Bacillus_phage	4.4e-33	32.4
BBD94969.1\|1430485_1431025_+	hypothetical protein	NA	NA	NA	NA
BBD94970.1\|1431187_1431436_-	ferredoxin	A0A127AYY7	Bacillus_phage	2.0e-16	50.7
BBD94971.1\|1431544_1432507_+	hypothetical protein	NA	NA	NA	NA
BBD94972.1\|1432493_1433873_+	probable ATP-dependent DNA helicase RecQ	M1PGQ0	Moumouvirus	8.1e-59	33.7

DBSCAN-SWA_6

1804981 : 1850335

Staphylococcus_phage(71.43%)

terminase,holin,protease,integrase,tail

attL 1837233:1837250|attR 1859412:1859429

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD95291.1\|1804981_1806364_-	hypothetical protein	A1BU77	Staphylococcus_virus	6.5e-258	89.6
BBD95292.1\|1806363_1806630_-\|holin	putative phage holin	A0A1W6JPF8	Staphylococcus_phage	1.3e-34	77.3
BBD95293.1\|1806681_1807077_-	hypothetical protein	A0A1W6JNM7	Staphylococcus_phage	2.4e-32	56.5
BBD95294.1\|1807063_1807486_-	hypothetical protein	A0A1W6JNI9	Staphylococcus_phage	4.7e-34	52.3
BBD95295.1\|1807523_1807664_-	hypothetical protein	NA	NA	NA	NA
BBD95296.1\|1807647_1808004_-	hypothetical protein	W5RV37	Staphylococcus_phage	7.7e-22	44.2
BBD95297.1\|1808018_1809737_-	hypothetical protein	A0A060AKT8	Staphylococcus_phage	4.7e-133	57.7
BBD95298.1\|1809736_1812400_-	hypothetical protein	A0A060AKF8	Staphylococcus_phage	4.3e-290	67.6
BBD95299.1\|1812411_1812855_-	hypothetical protein	Q4ZCD3	Staphylococcus_virus	1.3e-13	39.0
BBD95300.1\|1812847_1814419_-	hypothetical protein	A0A2H4J2R7	uncultured_Caudovirales_phage	2.4e-208	67.2
BBD95301.1\|1814427_1815264_-\|tail	putative phage tail component domain protein	A0A2H4J7E0	uncultured_Caudovirales_phage	3.9e-72	49.5
BBD95302.1\|1815278_1821455_-	phage protein	Q8LTH9	Staphylococcus_phage	1.4e-283	53.7
BBD95303.1\|1821469_1821628_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	3.5e-11	62.7
BBD95304.1\|1821678_1822020_-	phage protein	A0A0K1LKJ0	Staphylococcus_phage	7.9e-32	62.8
BBD95305.1\|1822061_1822289_-	phage protein	A0A1X9SIM4	Staphylococcus_phage	2.5e-10	50.7
BBD95306.1\|1822300_1822957_-	phage protein	A0A2I6PE59	Staphylococcus_phage	8.2e-86	75.9
BBD95307.1\|1822998_1823394_-	phage protein	A0A2I6PDD8	Staphylococcus_phage	8.0e-44	66.2
BBD95308.1\|1823395_1823797_-	hypothetical protein	R4WAN5	Staphylococcus_phage	1.8e-51	74.4
BBD95309.1\|1823793_1824156_-	phage protein	A0A2I6PDD6	Staphylococcus_phage	4.6e-22	43.9
BBD95310.1\|1824136_1824436_-	phage protein	A0A2H4JAM0	uncultured_Caudovirales_phage	1.8e-16	47.3
BBD95311.1\|1824504_1825641_-	phage protein	A0A1W6JPL4	Staphylococcus_phage	3.4e-156	76.3
BBD95312.1\|1825669_1826419_-	phage protein	A0A1W6JPK0	Staphylococcus_phage	2.3e-60	47.0
BBD95313.1\|1826405_1827566_-	phage protein	A0A2I6PDI1	Staphylococcus_phage	2.7e-116	53.2
BBD95314.1\|1827581_1829222_-\|terminase	phage protein, terminase	A0A059T7Q8	Listeria_phage	3.2e-227	69.3
BBD95315.1\|1829218_1829521_-	hypothetical protein	Q4ZD78	Staphylococcus_phage	4.4e-18	51.1
BBD95316.1\|1829669_1830005_-	phage-associated homing endonuclease	D2XR61	Bacillus_phage	4.1e-25	55.5
BBD95317.1\|1830139_1830574_-	phage regulatory protein	B5WZN8	Staphylococcus_phage	1.3e-66	88.1
BBD95318.1\|1830586_1830733_-	hypothetical protein	NA	NA	NA	NA
BBD95319.1\|1830750_1831350_-	hypothetical protein	D2JLD8	Staphylococcus_phage	1.8e-34	42.2
BBD95320.1\|1831351_1831507_-	hypothetical protein	NA	NA	NA	NA
BBD95321.1\|1831506_1831677_-	hypothetical protein	A0A1W6JPC7	Staphylococcus_phage	5.1e-16	76.5
BBD95322.1\|1831713_1832139_-	putative dUTP pyrophosphatase	A0A1W6JNN6	Staphylococcus_phage	5.2e-73	99.3
BBD95323.1\|1832138_1832309_-	hypothetical protein	A0A1W6JNR7	Staphylococcus_phage	6.3e-22	100.0
BBD95324.1\|1832446_1832623_-	hypothetical protein	A0A1W6JNN8	Staphylococcus_phage	1.2e-28	100.0
BBD95325.1\|1832609_1832888_-	hypothetical protein	NA	NA	NA	NA
BBD95326.1\|1832966_1833344_-	hypothetical protein	A0A2R3ZXY5	Staphylococcus_phage	6.5e-11	37.6
BBD95327.1\|1833340_1833778_-	phage DNA N-6-adenine-methyltransferase-like protein	A0A1W6JNN4	Staphylococcus_phage	8.5e-71	99.2
BBD95328.1\|1833774_1834182_-	hypothetical protein	A0A2H4J9W1	uncultured_Caudovirales_phage	5.4e-11	31.9
BBD95329.1\|1834195_1834354_-	hypothetical protein	A0A1W6JNP9	Staphylococcus_phage	1.4e-20	98.1
BBD95330.1\|1834356_1834545_-	hypothetical protein	NA	NA	NA	NA
BBD95331.1\|1834534_1834765_-	hypothetical protein	A0A0D4DCF1	Staphylococcus_phage	5.9e-23	68.6
BBD95332.1\|1834965_1835331_-	hypothetical protein	H9A0Z8	Staphylococcus_phage	1.2e-41	72.3
BBD95333.1\|1835331_1835526_-	hypothetical protein	A0A1W6JNR4	Staphylococcus_phage	9.7e-27	96.9
BBD95334.1\|1835518_1835926_-	hypothetical protein	A0A1W6JNS0	Staphylococcus_phage	1.6e-71	96.3
BBD95335.1\|1835934_1836180_-	hypothetical protein	A0A1W6JNN7	Staphylococcus_phage	3.0e-41	98.8
BBD95336.1\|1836182_1836338_-	hypothetical protein	A0A1W6JNM0	Staphylococcus_phage	2.8e-21	100.0
BBD95337.1\|1836331_1837102_-	DNA replication protein	A0A1W6JNQ7	Staphylococcus_phage	8.3e-138	95.7
BBD95338.1\|1837112_1837922_-	hypothetical protein	A6M985	Geobacillus_virus	3.5e-38	65.8
1837233:1837250	attL	NA	NA	NA	NA
BBD95339.1\|1837908_1838670_-	HNH endonuclease domain protein	A0A125RNK0	Pseudomonas_phage	2.0e-35	37.9
BBD95340.1\|1838662_1838869_-	hypothetical protein	Q4ZC20	Staphylococcus_virus	1.6e-19	66.2
BBD95341.1\|1838874_1839105_-	hypothetical protein	A0A1W6JPR2	Staphylococcus_phage	7.4e-26	71.1
BBD95342.1\|1839101_1839770_-	phage protein	A0A1W6JPR0	Staphylococcus_phage	1.9e-101	79.2
BBD95343.1\|1839770_1840319_-	hypothetical protein	A0A1W6JNF8	Staphylococcus_phage	2.4e-83	81.3
BBD95344.1\|1840331_1840886_-	single strand DNA binding protein	A0A0H3U303	Staphylococcus_phage	3.2e-91	88.6
BBD95345.1\|1840912_1841689_-	phage protein	Q8SDW5	Staphylococcus_phage	1.3e-125	87.3
BBD95346.1\|1841689_1842175_-	phage protein	A0A2H4JCW3	uncultured_Caudovirales_phage	2.5e-71	88.2
BBD95347.1\|1842140_1842422_-	hypothetical protein	A0A1W6JNM8	Staphylococcus_phage	3.1e-18	96.2
BBD95348.1\|1842483_1842657_-	hypothetical protein	A0A1W6JNL3	Staphylococcus_phage	1.9e-21	96.5
BBD95349.1\|1842670_1842880_-	hypothetical protein	A0A1W6JNP3	Staphylococcus_phage	2.6e-30	94.2
BBD95350.1\|1842968_1843445_+	hypothetical protein	NA	NA	NA	NA
BBD95351.1\|1843407_1843641_-	hypothetical protein	NA	NA	NA	NA
BBD95352.1\|1843679_1844471_-	anti-repressor protein	A0A2H4J5J5	uncultured_Caudovirales_phage	1.9e-116	80.6
BBD95353.1\|1844470_1844665_-	phage protein	A0A0F6N3M9	Staphylococcus_phage	1.1e-22	89.1
BBD95354.1\|1844928_1845267_+	transcriptional regulator	R4IH08	Staphylococcus_phage	1.7e-42	74.5
BBD95355.1\|1845280_1845952_+	hypothetical protein	A0A0F6N3H6	Staphylococcus_phage	5.0e-46	46.6
BBD95356.1\|1845978_1846554_+	hypothetical protein	A0A2H4IYV6	uncultured_Caudovirales_phage	3.5e-16	68.6
BBD95357.1\|1846787_1847219_+\|protease	CAAX amino protease	A0A2H4JB40	uncultured_Caudovirales_phage	1.8e-33	56.2
BBD95358.1\|1847148_1847871_+\|protease	CAAX amino protease	A0A2H4JB40	uncultured_Caudovirales_phage	2.8e-42	46.5
BBD95359.1\|1847934_1848981_+\|integrase	integrase	A0A2H4J9L9	uncultured_Caudovirales_phage	1.2e-147	73.0
BBD95360.1\|1849239_1849749_-	hypothetical protein	NA	NA	NA	NA
BBD95361.1\|1849741_1850335_-	non-canonical purine NTP pyrophosphatase	D2KCJ6	Cassava_brown_streak_virus	7.6e-14	31.1
1859412:1859429	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1939446 : 1947916

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD95449.1\|1939446_1940013_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.8e-31	41.2
BBD95450.1\|1940009_1941044_-	phosphoribosylformylglycinamidine cyclo-ligase PurM	Q58MH8	Prochlorococcus_phage	4.1e-63	42.7
BBD95451.1\|1941036_1942521_-	phosphoribosylpyrophosphate amidotransferase PurF	A0A0M3SGR2	Mollivirus	9.0e-48	32.8
BBD95452.1\|1942499_1944689_-	phosphoribosylformylglycinamidine synthase I PurQ	A6N228	Microbacterium_phage	7.4e-139	40.5
BBD95453.1\|1944681_1945353_-	phosphoribosylformylglycinamidine synthase I PurQ	NA	NA	NA	NA
BBD95454.1\|1945354_1945615_-	phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
BBD95455.1\|1945611_1946319_-	phosphoribosylaminoimidazole-succinocarboxamide synthase	H8ZMN3	Synechococcus_phage	5.6e-48	43.8
BBD95456.1\|1946319_1947447_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
BBD95457.1\|1947433_1947916_-	putative Phosphoribosylaminoimidazolecarboxylase, catalytic subunit	A0A2P0VNU7	Tetraselmis_virus	1.8e-21	42.7

DBSCAN-SWA_8

2187526 : 2196441

uncultured_Caudovirales_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD95696.1\|2187526_2188306_-	iron complex transport system ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	4.8e-16	32.0
BBD95697.1\|2188302_2189262_-	iron complex transport system permease protein	A0A2H4J116	uncultured_Caudovirales_phage	2.9e-15	92.0
BBD95698.1\|2189245_2190220_-	iron complex transport system permease protein	A0A2H4IY97	uncultured_Caudovirales_phage	1.2e-160	95.0
BBD95699.1\|2190203_2190404_-	hypothetical protein	NA	NA	NA	NA
BBD95700.1\|2190475_2191444_-	ribonucleoside-diphosphate reductase minor subunit	A0A2H4J4P3	uncultured_Caudovirales_phage	3.8e-180	96.9
BBD95701.1\|2191564_2193670_-	ribonuceloside diphosphate reductase major subunit	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	95.9
BBD95702.1\|2193632_2194031_-	ribonucleotide reductase stimulatory protein	A0A2H4J545	uncultured_Caudovirales_phage	2.7e-63	89.4
BBD95703.1\|2195060_2195927_+	putative transporter	NA	NA	NA	NA
BBD95704.1\|2195940_2196441_+	NADPH-dependent 7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	4.5e-52	72.3

DBSCAN-SWA_9

2214480 : 2224374

Pandoravirus(11.11%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBD95718.1\|2214480_2215641_-	para-aminobenzoate synthase component I	A0A0B5J984	Pandoravirus	3.4e-26	35.7
BBD95719.1\|2215630_2216218_-	para-aminobenzoate synthetase component II	A0A0P0IKJ1	Acinetobacter_phage	2.6e-38	42.7
BBD95720.1\|2216524_2217196_+	7-cyano-7-deazaguanine synthase	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.2e-65	56.3
BBD95721.1\|2217197_2217617_+	6-pyruvoyl tetrahydropterin synthase	S4U060	uncultured_phage	2.4e-06	23.5
BBD95722.1\|2217620_2218334_+	coenzyme PQQ synthesis homologue	A0A1U9WRB6	Streptococcus_virus	2.1e-50	42.7
BBD95723.1\|2218430_2219030_+	hypothetical protein	NA	NA	NA	NA
BBD95724.1\|2219449_2219887_+	putative lipoprotein	NA	NA	NA	NA
BBD95725.1\|2219940_2220414_+	putative thiosulfate dehydrogenase [quinone] large subunit	NA	NA	NA	NA
BBD95726.1\|2220388_2221078_+	response regulator saeR	W8CYM9	Bacillus_phage	3.7e-36	37.0
BBD95727.1\|2221080_2222136_+	histidine protein kinase saeS	A0A1V0SGX0	Hokovirus	2.8e-19	30.4
BBD95728.1\|2222205_2223315_-	hypothetical protein	A8CG95	Salmonella_phage	1.4e-61	42.5
BBD95729.1\|2223534_2224374_-	oxidoreductase, aldo/keto reductase family	A0A2H4PQR8	Staphylococcus_phage	4.9e-59	42.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. AP018587

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection