CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP019299	Streptococcus pneumoniae strain HKU1-14 chromosome, complete genome	1 crisprs	DEDDh,PrimPol,cas3,DinG,RT	0	0	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP019299_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP019299_1

94735-94830

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP019299_1

>merge|CP019299|1|94735-94830|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>CP019299|1|1|94735-94830|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
CP019299.1\|AZT86450.1\|102520_103384_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP019299.1\|AZT86433.1\|85657_86587_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
CP019299.1\|AZT86444.1\|97278_99129_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
CP019299.1\|AZT86446.1\|99433_100066_-\|pyrophosphatase-PpaX	unknown	unknown	gnl\|CDD\|319798
CP019299.1\|AZT86443.1\|96079_97237_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
CP019299.1\|AZT86442.1\|94855_96022_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225365
CP019299.1\|AZT86447.1\|100087_100960_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
CP019299.1\|AZT86441.1\|94390_94717_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
CP019299.1\|AZT86439.1\|92906_93818_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372574
CP019299.1\|AZT86435.1\|87733_89209_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
CP019299.1\|AZT86437.1\|90741_91602_+\|DUF4299-domain-containing-protein	unknown	unknown	gnl\|CDD\|339103
CP019299.1\|AZT86451.1\|104020_104401_+\|argininosuccinate-lyase	unknown	unknown	unknown
CP019299.1\|AZT86434.1\|86600_87524_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
CP019299.1\|AZT86432.1\|85018_85339_+\|hypothetical-protein	unknown	unknown	unknown
CP019299.1\|AZT86440.1\|93810_94404_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
CP019299.1\|AZT86445.1\|99153_99384_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|165285
CP019299.1\|AZT86449.1\|101881_102469_+\|LysM-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
CP019299.1\|AZT86448.1\|100968_101640_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
CP019299.1\|AZT86438.1\|91779_92844_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374284
CP019299.1\|AZT86436.1\|89480_90467_+\|rhodanese-domain-containing-protein	unknown	unknown	gnl\|CDD\|234663

Protein	Function_ID	Function_description	E-value
CP019299.1\|AZT86434.1\|86600_87524_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69
CP019299.1\|AZT86433.1\|85657_86587_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
CP019299.1\|AZT86444.1\|97278_99129_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
CP019299.1\|AZT86446.1\|99433_100066_-\|pyrophosphatase-PpaX	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.0375e-97
CP019299.1\|AZT86448.1\|100968_101640_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
CP019299.1\|AZT86442.1\|94855_96022_-\|MFS-transporter	gnl\|CDD\|225365	COG2807, CynX, Cyanate permease [Inorganic ion transport and metabolism].	1.0335e-125
CP019299.1\|AZT86447.1\|100087_100960_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	2.65225e-106
CP019299.1\|AZT86441.1\|94390_94717_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19
CP019299.1\|AZT86439.1\|92906_93818_-\|hypothetical-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	5.1542e-40
CP019299.1\|AZT86435.1\|87733_89209_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.24398e-44
CP019299.1\|AZT86437.1\|90741_91602_+\|DUF4299-domain-containing-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	7.97807e-120
CP019299.1\|AZT86443.1\|96079_97237_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	3.88139e-109
CP019299.1\|AZT86450.1\|102520_103384_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.85625e-10
CP019299.1\|AZT86440.1\|93810_94404_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	7.70935e-64
CP019299.1\|AZT86445.1\|99153_99384_-\|hypothetical-protein	gnl\|CDD\|165285	PHA02982, PHA02982, hypothetical protein; Provisional.	0.00977901
CP019299.1\|AZT86449.1\|101881_102469_+\|LysM-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	5.22512e-13
CP019299.1\|AZT86438.1\|91779_92844_-\|hypothetical-protein	gnl\|CDD\|374284	pfam16001, DUF4775, Domain of unknown function (DUF4775). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.	0.000907411
CP019299.1\|AZT86436.1\|89480_90467_+\|rhodanese-domain-containing-protein	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0

>CP019299.1|AZT86441.1|94390_94717_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>CP019299.1|AZT86440.1|93810_94404_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA
>CP019299.1|AZT86439.1|92906_93818_-|hypothetical-protein
MRKWTKRFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAENIQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>CP019299.1|AZT86438.1|91779_92844_-|hypothetical-protein
MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>CP019299.1|AZT86437.1|90741_91602_+|DUF4299-domain-containing-protein
MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQPLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYTGTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLAQFEARVRAVQETDAYFARVSFYQDREGEVHGVYRLAQGVKTVLPREPFVPAAYIEQLMDKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILDKDFKTLAQEK
>CP019299.1|AZT86436.1|89480_90467_+|rhodanese-domain-containing-protein
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>CP019299.1|AZT86435.1|87733_89209_+|DUF3502-domain-containing-protein
MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>CP019299.1|AZT86434.1|86600_87524_+|carbohydrate-ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>CP019299.1|AZT86433.1|85657_86587_+|sugar-ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>CP019299.1|AZT86432.1|85018_85339_+|hypothetical-protein
MRSLTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAIASLESIKESQSATKDVLENSQEELQKAVLFLADEKGSEHTEAELIDNLKEVIAKLKANA
>CP019299.1|AZT86442.1|94855_96022_-|MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSSQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIAAALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL
>CP019299.1|AZT86443.1|96079_97237_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML
>CP019299.1|AZT86444.1|97278_99129_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>CP019299.1|AZT86445.1|99153_99384_-|hypothetical-protein
MKIKEQTRKLAAGCSKHCFKVVARTDEVSSKHCFEVVDRTDEVSNHTYGKATLTWFEEIFEEYKSLHNKTHITKVV
>CP019299.1|AZT86446.1|99433_100066_-|pyrophosphatase-PpaX
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>CP019299.1|AZT86447.1|100087_100960_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>CP019299.1|AZT86448.1|100968_101640_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>CP019299.1|AZT86449.1|101881_102469_+|LysM-domain-containing-protein
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETVSAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>CP019299.1|AZT86450.1|102520_103384_-|XRE-family-transcriptional-regulator
MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPKYENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQDYLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLKILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMCKQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQAKER
>CP019299.1|AZT86451.1|104020_104401_+|argininosuccinate-lyase
MELVLPNNYVALEQEEMMYLDGGGVGCNWWNSRGSFATVLDVGLAIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTGFSLGGAIAYGADWADGSLDGYIFA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

39780 : 51236

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT86394.1\|39780_41934_+	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	4.0e-44	27.8
AZT86395.1\|41946_43296_+	multidrug transporter subunit MdtN	NA	NA	NA	NA
AZT86396.1\|43423_44173_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	1.4e-41	39.2
AZT88241.1\|44174_44318_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
AZT86397.1\|44374_48100_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	5.6e-38	25.9
AZT86398.1\|48192_49635_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-55	35.1
AZT86399.1\|49671_50694_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	1.2e-64	43.9
AZT86400.1\|50690_51236_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.4e-24	35.0

DBSCAN-SWA_2

115512 : 163495

Staphylococcus_phage(33.33%)

bacteriocin,tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT86459.1\|115512_116634_+\|tRNA	tRNA(5-methylaminomethyl-2-thiouridine)- methyltransferase	NA	NA	NA	NA
AZT86460.1\|116747_117230_+	Nudix family hydrolase	NA	NA	NA	NA
AZT86461.1\|117239_119153_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
AZT86462.1\|119486_121166_-	ribonuclease J	NA	NA	NA	NA
AZT86463.1\|121167_121401_-	hypothetical protein	NA	NA	NA	NA
AZT86464.1\|121784_122006_+	hypothetical protein	NA	NA	NA	NA
AZT86465.1\|122027_122225_-	hypothetical protein	NA	NA	NA	NA
AZT86466.1\|122218_122371_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
AZT86467.1\|122373_122559_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
AZT86468.1\|122736_123420_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
AZT86469.1\|123416_123854_+	ribosomal-protein-alanine N-acetyltransferase	NA	NA	NA	NA
AZT86470.1\|123843_124854_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A291ATS8	Pandoravirus	5.6e-41	36.9
AZT86471.1\|127460_128675_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
AZT86472.1\|129325_130942_+	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	3.0e-28	36.0
AZT86473.1\|131202_131631_+	hypothetical protein	NA	NA	NA	NA
AZT86474.1\|131636_132392_+	PIG-L family deacetylase	NA	NA	NA	NA
AZT86475.1\|133971_134835_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZT86476.1\|135120_135354_+	hypothetical protein	NA	NA	NA	NA
AZT86477.1\|135375_136053_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AZT86478.1\|136064_136730_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AZT86479.1\|136798_138028_+	MFS transporter	NA	NA	NA	NA
AZT86480.1\|138210_139557_+\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	7.6e-78	40.0
AZT86481.1\|139621_139804_-	hypothetical protein	NA	NA	NA	NA
AZT86482.1\|140189_140804_+	AzlC protein	NA	NA	NA	NA
AZT86483.1\|140907_141738_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AZT86484.1\|141959_142790_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
AZT86485.1\|142943_143798_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
AZT86486.1\|143897_145271_+	peptidase M20	NA	NA	NA	NA
AZT86487.1\|145263_146325_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.7e-29	35.7
AZT86488.1\|146326_147019_+	ABC transporter permease	NA	NA	NA	NA
AZT86489.1\|147048_147618_-	hypothetical protein	NA	NA	NA	NA
AZT86490.1\|147752_148367_+	DUF624 domain-containing protein	NA	NA	NA	NA
AZT86491.1\|148344_150015_+	sensor histidine kinase	NA	NA	NA	NA
AZT86492.1\|150026_151313_+	DNA-binding response regulator	NA	NA	NA	NA
AZT86493.1\|151316_151898_+	ABC transporter permease	NA	NA	NA	NA
AZT86494.1\|151975_152446_+	ribonucleotide reductase assembly protein NrdI	NA	NA	NA	NA
AZT88245.1\|152471_152558_-	DNA alkylation repair protein	NA	NA	NA	NA
AZT86495.1\|152738_154001_-	divalent metal cation transporter	NA	NA	NA	NA
AZT86496.1\|154310_154769_-	DUF3021 domain-containing protein	NA	NA	NA	NA
AZT86497.1\|154765_155206_-	DNA-binding response regulator	NA	NA	NA	NA
AZT86498.1\|155445_155541_+	hypothetical protein	NA	NA	NA	NA
AZT86499.1\|155561_157511_+	DNA mismatch repair protein HexB	A0A1B2LRQ5	Wolbachia_phage	1.0e-70	32.1
AZT86500.1\|157835_158303_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	3.7e-40	52.6
AZT88246.1\|158303_159509_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.7e-106	49.5
AZT86501.1\|159528_160164_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.3e-43	46.9
AZT86502.1\|160148_161249_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	3.8e-51	38.2
AZT86503.1\|161654_162248_+	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
AZT86504.1\|162257_162821_+	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
AZT86505.1\|162817_163495_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_3

166735 : 174905

Streptococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT86509.1\|166735_167902_-	tyrosine recombinase XerS	A0A1X9I5Y5	Streptococcus_phage	1.6e-153	69.8
AZT86510.1\|168235_169225_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	5.2e-76	46.5
AZT86511.1\|169312_169948_-	XRE family transcriptional regulator	Q708R9	Streptococcus_phage	1.1e-13	47.6
AZT86512.1\|170100_170319_+	XRE family transcriptional regulator	NA	NA	NA	NA
AZT86513.1\|170332_170959_+	hypothetical protein	R9QNB1	Lactococcus_phage	2.7e-30	41.3
AZT86514.1\|171393_171792_+	hypothetical protein	NA	NA	NA	NA
AZT86515.1\|171788_172004_+	hypothetical protein	NA	NA	NA	NA
AZT86516.1\|172000_172342_+	DNA-binding protein	NA	NA	NA	NA
AZT86517.1\|172334_172616_+	transcriptional regulator	A0A1X9I5U9	Streptococcus_phage	5.7e-28	62.9
AZT86518.1\|172602_173400_+	DnaD domain protein	A0A1L2JYQ3	Streptococcus_phage	4.7e-67	65.0
AZT86519.1\|173415_174240_+	GTP-binding protein	A0A1X9I6C4	Streptococcus_phage	1.1e-47	37.7
AZT86520.1\|174371_174905_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.4e-38	49.7

DBSCAN-SWA_4

410271 : 454612

Only_Syngen_Nebraska_virus(20.0%)

bacteriocin,tRNA,integrase

attL 407264:407282|attR 443182:443200

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
407264:407282	attL	NA	NA	NA	NA
AZT86742.1\|410271_410775_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
AZT86743.1\|411227_411791_+	ECF transporter S component	NA	NA	NA	NA
AZT86744.1\|411780_412431_+	phosphatase PAP2 family protein	NA	NA	NA	NA
AZT86745.1\|412458_412848_+	chromosome partitioning protein ParB	NA	NA	NA	NA
AZT86746.1\|412852_413302_+	N-acetyltransferase	NA	NA	NA	NA
AZT86747.1\|413414_414017_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
AZT86748.1\|414406_416014_+	CTP synthetase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.9e-142	47.0
AZT86749.1\|416572_418204_-	sodium-dependent phosphate transporter	NA	NA	NA	NA
AZT86750.1\|418496_423437_+	endo-beta-N-acetylglucosaminidase	NA	NA	NA	NA
AZT86751.1\|423526_424723_+	phosphoglycerate kinase	NA	NA	NA	NA
AZT86752.1\|424858_425386_+	aromatic acid exporter family protein	NA	NA	NA	NA
AZT86753.1\|425462_425819_+	MerR family transcriptional regulator	NA	NA	NA	NA
AZT86754.1\|425855_427202_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
AZT86755.1\|427291_427411_-	glutamine synthetase	NA	NA	NA	NA
AZT86756.1\|427375_427525_+	cell envelope	NA	NA	NA	NA
AZT86757.1\|429205_429811_-	restriction endonuclease subunit S	NA	NA	NA	NA
AZT86758.1\|429821_430619_-\|integrase	integrase	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
AZT86759.1\|432239_433703_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
AZT86760.1\|433715_436049_-	restriction endonuclease subunit R	A0A097BY72	Enterococcus_phage	1.2e-25	26.5
AZT86761.1\|436420_436621_+	hypothetical protein	NA	NA	NA	NA
AZT86762.1\|436655_437165_+	DUF2812 domain-containing protein	NA	NA	NA	NA
AZT86763.1\|437328_438363_+	HrcA family transcriptional regulator	NA	NA	NA	NA
AZT86764.1\|438389_438914_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
AZT86765.1\|441216_441573_+\|tRNA	tRNA (guanine-N7)-methyltransferase	NA	NA	NA	NA
AZT86766.1\|443127_443349_-	hypothetical protein	NA	NA	NA	NA
443182:443200	attR	NA	NA	NA	NA
AZT86767.1\|443432_443720_-	hypothetical protein	NA	NA	NA	NA
AZT86768.1\|443729_444140_-	HIT family protein	B5LJ12	Mycobacterium_phage	1.2e-05	31.6
AZT86769.1\|444207_444939_+	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	1.1e-25	29.0
AZT86770.1\|444935_445985_+	multidrug ABC transporter permease	NA	NA	NA	NA
AZT86771.1\|446152_446482_-	helicase BlpT	NA	NA	NA	NA
AZT86772.1\|446757_447096_+	DNA-binding response regulator	NA	NA	NA	NA
AZT86773.1\|447100_447838_+	DNA-binding response regulator	NA	NA	NA	NA
AZT86774.1\|447851_449192_+	ATP-binding protein	NA	NA	NA	NA
AZT86775.1\|449235_449391_-	quorum-sensing system pheromone BlpC	NA	NA	NA	NA
AZT86776.1\|449447_450809_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
AZT86777.1\|452388_452976_-	Xaa-Pro dipeptidase	NA	NA	NA	NA
AZT86778.1\|453257_453455_+\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
AZT86779.1\|453459_453621_+	immunity protein	NA	NA	NA	NA
AZT86780.1\|453921_454191_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
AZT86781.1\|454259_454490_+\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
AZT86782.1\|454492_454612_+\|bacteriocin	bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_5

795996 : 823766

Streptococcus_phage(82.61%)

integrase,transposase

attL 795752:795773|attR 823101:823122

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
795752:795773	attL	NA	NA	NA	NA
AZT87079.1\|795996_798183_+	radical SAM protein	A0A1L7N0Q5	Ralstonia_phage	6.7e-07	21.4
AZT87080.1\|798184_798451_+	CXXX repeat peptide modification system protein	NA	NA	NA	NA
AZT87081.1\|799782_799902_+	hypothetical protein	NA	NA	NA	NA
AZT87082.1\|799924_800239_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
AZT87083.1\|800254_800641_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
AZT87084.1\|800669_802055_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AZT87085.1\|802057_802210_+	conjugal transfer protein	NA	NA	NA	NA
AZT87086.1\|802232_803651_+	helix-turn-helix domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.5e-233	100.0
AZT87087.1\|803907_804645_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.1e-134	99.2
AZT87088.1\|804649_804781_+	hypothetical protein	E4ZFP9	Streptococcus_phage	7.9e-17	100.0
AZT87089.1\|804901_806149_-\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	3.9e-12	23.9
AZT87090.1\|806328_806550_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AZT87091.1\|806666_807164_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AZT87092.1\|807250_807643_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	4.6e-68	99.2
AZT87093.1\|807626_810074_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	98.4
AZT87094.1\|810076_812260_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	2.9e-305	82.3
AZT87095.1\|812256_813258_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.5e-190	99.7
AZT87096.1\|813254_814187_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
AZT87097.1\|814461_814548_+	tetracycline resistance protein	NA	NA	NA	NA
AZT87098.1\|814563_816483_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A2K5B2A5	Erysipelothrix_phage	0.0e+00	96.9
AZT87099.1\|816583_816769_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
AZT87100.1\|816828_817182_-	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AZT88266.1\|817386_817458_+	hypothetical protein	NA	NA	NA	NA
AZT87101.1\|817686_818109_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
AZT87102.1\|818105_818336_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
AZT87103.1\|818561_818813_-	hypothetical protein	NA	NA	NA	NA
AZT87104.1\|818796_819000_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AZT87105.1\|819081_820299_+\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	1.6e-231	99.0
AZT87106.1\|821182_821911_+	hypothetical protein	NA	NA	NA	NA
AZT87107.1\|822067_822415_+	DUF3784 domain-containing protein	NA	NA	NA	NA
AZT87108.1\|823196_823766_+	hypothetical protein	Q938J0	Temperate_phage	4.9e-34	40.4
823101:823122	attR	NA	NA	NA	NA

DBSCAN-SWA_6

883831 : 895719

Streptococcus_phage(72.73%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT87160.1\|883831_884740_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	5.2e-06	27.7
AZT87161.1\|884736_885198_+	signal peptidase II	NA	NA	NA	NA
AZT87162.1\|885187_886075_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.3e-09	28.0
AZT87163.1\|886077_887961_+	MBL fold metallo-hydrolase	Q332B9	Clostridium_botulinum_C_phage	9.5e-10	23.7
AZT87164.1\|888040_889171_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.5e-114	58.1
AZT87165.1\|889180_890443_+	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	2.5e-139	64.5
AZT87166.1\|890446_891244_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	2.7e-59	50.6
AZT87167.1\|891463_892102_+	thymidylate kinase	M1PSC7	Streptococcus_phage	1.7e-75	68.1
AZT87168.1\|892098_892989_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.9e-73	51.7
AZT87169.1\|893028_893346_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
AZT87170.1\|893348_894218_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	5.9e-116	75.7
AZT87171.1\|894444_894963_+	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
AZT87172.1\|895071_895719_+	hypothetical protein	A0A2P0VK56	Streptococcus_phage	7.0e-13	33.7

DBSCAN-SWA_7

1125672 : 1186104

Bacillus_phage(17.65%)

protease,bacteriocin,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT87385.1\|1125672_1125948_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AZT87386.1\|1126215_1127094_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
AZT87387.1\|1127103_1128378_-	DUF2130 domain-containing protein	NA	NA	NA	NA
AZT87388.1\|1129880_1130678_-	formate-nitrite transporter	NA	NA	NA	NA
AZT87389.1\|1130921_1131665_-	sortase	NA	NA	NA	NA
AZT87390.1\|1131664_1134133_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	3.5e-105	35.5
AZT87391.1\|1134326_1135313_+	L-lactate dehydrogenase	NA	NA	NA	NA
AZT87392.1\|1135575_1136349_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	4.0e-23	47.1
AZT87393.1\|1136395_1136659_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
AZT87394.1\|1136651_1136954_-	antitoxin	NA	NA	NA	NA
AZT87395.1\|1136984_1137794_-	MBL fold metallo-hydrolase	A0A0C5AFC1	Paenibacillus_phage	1.8e-34	39.0
AZT87396.1\|1137795_1139145_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	1.8e-34	34.6
AZT87397.1\|1139137_1139842_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.8e-39	39.8
AZT87398.1\|1139896_1141072_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
AZT87399.1\|1141399_1143070_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
AZT87400.1\|1143299_1143989_+	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
AZT87401.1\|1144000_1144552_+	phosphopantothenoylcysteine decarboxylase	A0A068EHP1	Penguinpox_virus	5.2e-25	37.6
AZT87402.1\|1144535_1145099_+	ECF transporter S component	NA	NA	NA	NA
AZT87403.1\|1145380_1145908_+	hypothetical protein	NA	NA	NA	NA
AZT87404.1\|1145919_1146435_+	transcription repressor NadR	NA	NA	NA	NA
AZT87405.1\|1146431_1146899_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
AZT87406.1\|1146970_1147459_-	N-acetyltransferase	NA	NA	NA	NA
AZT87407.1\|1147424_1147988_-	N-acetyltransferase	NA	NA	NA	NA
AZT87408.1\|1147997_1149986_-	excinuclease ABC subunit B	NA	NA	NA	NA
AZT87409.1\|1150062_1151016_-\|protease	CPBP family intramembrane metalloprotease domain-containing protein	NA	NA	NA	NA
AZT87410.1\|1151184_1153350_+	amino acid ABC transporter permease	NA	NA	NA	NA
AZT87411.1\|1153349_1154090_+	amino acid ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.8e-18	27.3
AZT87412.1\|1154238_1155726_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	1.0e-70	33.1
AZT87413.1\|1155769_1157059_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
AZT87414.1\|1157062_1157881_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AZT87415.1\|1157880_1158675_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AZT87416.1\|1158671_1162211_-	chromosome segregation protein SMC	NA	NA	NA	NA
AZT87417.1\|1162201_1162900_-	ribonuclease 3	J2YAN1	Acanthamoeba_polyphaga_lentillevirus	3.0e-25	33.8
AZT87418.1\|1163217_1164204_-	guanosine monophosphate reductase	G3MBI2	Bacillus_virus	1.4e-137	72.2
AZT87419.1\|1164378_1165695_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
AZT87420.1\|1165681_1167598_-	endonuclease	K4I1H4	Acidithiobacillus_phage	1.8e-16	33.7
AZT87421.1\|1167760_1167931_-	hypothetical protein	NA	NA	NA	NA
AZT87422.1\|1167911_1168085_-	hypothetical protein	NA	NA	NA	NA
AZT87423.1\|1168546_1168906_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
AZT87424.1\|1168909_1169179_-	DUF1294 domain-containing protein	NA	NA	NA	NA
AZT87425.1\|1169175_1170213_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
AZT87426.1\|1170224_1171319_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	3.1e-05	38.9
AZT87427.1\|1171337_1171994_-	MmcQ family protein	NA	NA	NA	NA
AZT87428.1\|1172037_1172670_-	copper homeostasis protein CutC	NA	NA	NA	NA
AZT87429.1\|1172762_1173122_-	DUF454 domain-containing protein	NA	NA	NA	NA
AZT87430.1\|1173342_1175430_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	5.1e-105	37.6
AZT87431.1\|1175596_1176640_-	TIGR00341 family protein	NA	NA	NA	NA
AZT87432.1\|1177523_1178372_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.2e-34	39.5
AZT87433.1\|1178467_1179157_-\|holin	CTP--phosphocholine cytidylyltransferase	A0A127AW70	Bacillus_phage	3.4e-05	45.0
AZT87434.1\|1179168_1180047_-	EamA/RhaT family transporter	NA	NA	NA	NA
AZT87435.1\|1180036_1180906_-\|holin	choline kinase	NA	NA	NA	NA
AZT87436.1\|1180922_1181945_-	ribitol-5-phosphate dehydrogenase	NA	NA	NA	NA
AZT87437.1\|1181949_1182657_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
AZT87438.1\|1182992_1184480_+	virulence factor MviN	NA	NA	NA	NA
AZT87439.1\|1184489_1185293_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	5.3e-10	27.1
AZT87440.1\|1185294_1186104_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	2.6e-09	30.3

DBSCAN-SWA_8

1298802 : 1304581

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT87552.1\|1298802_1299414_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
AZT87553.1\|1299458_1300187_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
AZT87554.1\|1300225_1301137_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	4.5e-90	51.8
AZT87555.1\|1301202_1301439_-	DUF4059 domain-containing protein	NA	NA	NA	NA
AZT87556.1\|1301504_1302248_-	L-cystine ABC transporter ATP-binding protein YecC	G9BWD6	Planktothrix_phage	4.7e-29	40.5
AZT87557.1\|1302247_1303048_-	amino acid ABC transporter permease	NA	NA	NA	NA
AZT87558.1\|1303205_1303562_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
AZT87559.1\|1303574_1304087_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.3e-46	55.6
AZT87560.1\|1304086_1304581_-	N-acetyltransferase	M1PSC3	Streptococcus_phage	8.5e-43	52.8

DBSCAN-SWA_9

1395001 : 1401755

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT87643.1\|1395001_1395970_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
AZT87644.1\|1396003_1396915_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.6e-154	99.3
AZT87645.1\|1396911_1397889_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
AZT87646.1\|1397885_1398776_-	RNase adaptor protein RapZ	A0A0R8VB27	Thermobifida_phage	6.7e-06	29.8
AZT87647.1\|1398827_1399208_-	RidA family protein	NA	NA	NA	NA
AZT87648.1\|1399218_1399806_-	GTP-binding protein	NA	NA	NA	NA
AZT87649.1\|1399814_1401047_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.2e-131	59.0
AZT87650.1\|1401078_1401249_-	hypothetical protein	NA	NA	NA	NA
AZT87651.1\|1401248_1401755_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	1.1e-26	41.9

DBSCAN-SWA_10

1650680 : 1658012

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT87893.1\|1650680_1651382_+	UDP-glucose 4-epimerase	A0A2K9L1R4	Tupanvirus	1.7e-33	35.1
AZT87894.1\|1651397_1651508_+	UDP-glucose 4-epimerase	NA	NA	NA	NA
AZT87895.1\|1651789_1652764_+	ferrichrome ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.8e-57	40.8
AZT87896.1\|1652753_1653710_+	ferrichrome ABC transporter permease	NA	NA	NA	NA
AZT87897.1\|1653706_1654459_+	iron ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-14	28.1
AZT87898.1\|1654554_1655520_+	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
AZT87899.1\|1655744_1655987_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.7e-17	59.4
AZT87900.1\|1655986_1656709_-	rRNA pseudouridine synthase	NA	NA	NA	NA
AZT87901.1\|1656695_1657265_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
AZT87902.1\|1657283_1658012_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.3e-09	22.3

DBSCAN-SWA_11

2015778 : 2024532

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZT88217.1\|2015778_2016618_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	1.1e-15	32.6
AZT88218.1\|2016602_2017430_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	3.5e-17	33.3
AZT88219.1\|2017426_2017972_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
AZT88220.1\|2017982_2018813_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZT88221.1\|2018845_2020129_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	8.4e-18	30.0
AZT88222.1\|2020125_2021376_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.7e-93	42.3
AZT88223.1\|2021534_2021903_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	57.3
AZT88224.1\|2021905_2023003_+	DNA replication and repair protein RecF	NA	NA	NA	NA
AZT88225.1\|2023053_2024532_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	40.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage