CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
AP019371	Actinoplanes sp. OR16 DNA, complete genome	14 crisprs	cas4,DinG,csa3,cas3,DEDDh,WYL	6	8	1	0

1. AP019371

CRISPR-Cas detection and classification

Crispr_ID: AP019371_1

• CRISPR_ID: AP019371_1
• CRISPR_location: 1157936-1158025
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_1

Consensus_repeat	Method
CGTCGACCTCCGAATGCGTGCGTTCGCCG	CRISPRCasFinder

spacers of AP019371_1

>1.1|1157965|32|AP019371|CRISPRCasFinder
GTCCGGCAGCGCAACCGCTCCGCAGGGCAGGG

CRISPR arrays and Neighbor proteins around AP019371_1

CRISPR arrays

The CRISPR arrays of AP019371_1

>merge|AP019371|1|1157936-1158025|CRISPRCasFinder
CGTCGACCTCCGAATGCGTGCGTTCGCCGGTCCGGCAGCGCAACCGCTCCGCAGGGCAGGGCGTCGACCTCCGAGTGCGTGCGTTCGCCG

>AP019371|1|1|1157936-1158025|CRISPRCasFinder
CGTCGACCTCCGAATGCGTGCGTTCGCCG	GTCCGGCAGCGCAACCGCTCCGCAGGGCAGGG
CGTCGACCTCCGAGTGCGTGCGTTCGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH64365.1|1149713_1150217_+|RNA-polymerase-sigma24-factor	unknown	unknown	gnl|CDD|132028
AP019371.1|BBH64376.1|1165630_1166605_+|glycosyltransferase	unknown	unknown	gnl|CDD|133030
AP019371.1|BBH64364.1|1148268_1149660_+|hypothetical-protein	unknown	unknown	gnl|CDD|379140
AP019371.1|BBH64373.1|1161193_1163386_+|antifreeze-protein,-type-I	unknown	unknown	gnl|CDD|340818
AP019371.1|BBH64369.1|1154321_1154552_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH64370.1|1154769_1156530_+|exopolysaccharide-phosphotransferase	unknown	unknown	gnl|CDD|371500
AP019371.1|BBH64368.1|1152719_1154258_-|signal-recognition-particle-protein	unknown	unknown	gnl|CDD|236780
AP019371.1|BBH64375.1|1164050_1165634_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH64366.1|1150206_1151616_+|hypothetical-protein	unknown	unknown	gnl|CDD|379140
AP019371.1|BBH64380.1|1170313_1172779_-|hypothetical-protein	unknown	unknown	gnl|CDD|132997
AP019371.1|BBH64378.1|1167149_1169207_-|acyltransferase	unknown	unknown	gnl|CDD|224748
AP019371.1|BBH64371.1|1156541_1157804_+|UDP-N-acetyl-D-glucosamine-dehydrogenase	unknown	unknown	gnl|CDD|223749
AP019371.1|BBH64363.1|1147760_1148258_+|RNA-polymerase-sigma24-factor	unknown	unknown	gnl|CDD|132028
AP019371.1|BBH64362.1|1146290_1147697_-|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236327
AP019371.1|BBH64379.1|1169210_1170257_-|hypothetical-protein	unknown	unknown	gnl|CDD|379276
AP019371.1|BBH64367.1|1151617_1152694_-|amidohydrolase	unknown	unknown	gnl|CDD|238624
AP019371.1|BBH64381.1|1172853_1175124_-|bifunctional-uridylyltransferase/uridylyl-removing-enzyme	unknown	unknown	gnl|CDD|235123
AP019371.1|BBH64374.1|1163388_1164039_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH64377.1|1166591_1166978_+|hypothetical-protein	unknown	unknown	gnl|CDD|377229
AP019371.1|BBH64372.1|1158597_1161066_-|hypothetical-protein	unknown	unknown	gnl|CDD|132997

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH64365.1|1149713_1150217_+|RNA-polymerase-sigma24-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	5.65557e-41
AP019371.1|BBH64376.1|1165630_1166605_+|glycosyltransferase	gnl|CDD|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	2.08677e-74
AP019371.1|BBH64364.1|1148268_1149660_+|hypothetical-protein	gnl|CDD|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	0.00645286
AP019371.1|BBH64373.1|1161193_1163386_+|antifreeze-protein,-type-I	gnl|CDD|340818	cd03785, GT28_MurG, undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	6.53799e-15
AP019371.1|BBH64366.1|1150206_1151616_+|hypothetical-protein	gnl|CDD|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	3.01799e-08
AP019371.1|BBH64368.1|1152719_1154258_-|signal-recognition-particle-protein	gnl|CDD|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
AP019371.1|BBH64370.1|1154769_1156530_+|exopolysaccharide-phosphotransferase	gnl|CDD|371500	pfam11380, Stealth_CR2, Stealth protein CR2, conserved region 2. Stealth_CR2 is the second of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. CR2 carries a well-conserved NDD sequence-motif. The domain is found in tandem with CR1, CR3 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system.	4.39525e-64
AP019371.1|BBH64380.1|1170313_1172779_-|hypothetical-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	3.49519e-25
AP019371.1|BBH64378.1|1167149_1169207_-|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	7.88351e-56
AP019371.1|BBH64371.1|1156541_1157804_+|UDP-N-acetyl-D-glucosamine-dehydrogenase	gnl|CDD|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	2.12815e-161
AP019371.1|BBH64363.1|1147760_1148258_+|RNA-polymerase-sigma24-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	5.38503e-35
AP019371.1|BBH64362.1|1146290_1147697_-|proline--tRNA-ligase	gnl|CDD|236327	PRK08661, PRK08661, prolyl-tRNA synthetase; Provisional.	0
AP019371.1|BBH64379.1|1169210_1170257_-|hypothetical-protein	gnl|CDD|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.47312e-11
AP019371.1|BBH64367.1|1151617_1152694_-|amidohydrolase	gnl|CDD|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	5.91884e-58
AP019371.1|BBH64381.1|1172853_1175124_-|bifunctional-uridylyltransferase/uridylyl-removing-enzyme	gnl|CDD|235123	PRK03381, PRK03381, PII uridylyl-transferase; Provisional.	0
AP019371.1|BBH64377.1|1166591_1166978_+|hypothetical-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	7.98673e-15
AP019371.1|BBH64372.1|1158597_1161066_-|hypothetical-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	7.37952e-25

Protein sequences

>AP019371.1|BBH64371.1|1156541_1157804_+|UDP-N-acetyl-D-glucosamine-dehydrogenase
MSYDVVILGLGYVGLPLAQQATRAGLSVLGFDVDETVVRALADGRSHVDDLSDSDVKAMVADGFLPTTDETLIAQARTAVICVPTPLSEGDGPDLRAVLGATSAVGRNLRPGMLVVLESTTYPGTTDDEVRPRLEQLSGLTAGIDFHLAFSPERIDPGNEVYGAHNTPKVVGGYTPSCTSAAAAFYGRFVETVVQTRGTREAETAKLLENTYRHVNIALVNEMARFCHELDIDLWDVIHAASTKPFGFQAFYPGPGVGGHCIPIDPNYLSHNVRSKLGYPFRFVELAQEINTTMPAYVARRAQNLLNADGQAVRGATVLLLGITYKANIADQRESPAAPLARQLAALGATVAYHDPHVRTWDIGGVPVSRTDDLEGATASADLVILVQNHREYDPDHLARIAKRFFDTRGVTSSREAHRL
>AP019371.1|BBH64370.1|1154769_1156530_+|exopolysaccharide-phosphotransferase
MRRKDDGVTLRQILRLTPWAVRRRIFTSAEKHLLPKITPERRLRVARTLMPLAPTRMPNRARVTRTGVARVRGVTARVVATATPAGVRRQNLDRVAEALDASGVDWFRLPGPTPLGTAVAVTENDRDRVLALLRDIAERDHGRLRTVLAARRGVPRVVSVCWPVTDPAGSLLLGGEYACEIEFWRHKDGRLVAPRRNQVADSIPAGEPSVIAPEPVFGPFSSPDDVTGYRTRPVFTAVDPDRIDFPIDVVYTWVDGGDPAWQRRKNRALDGNPWVSRINAQAANDSRYASRDELRYSLRALHCFAPWVRRIFLVTDDQVPAWLDLTDPRITLVGHQEIFGDTGTLPTFNSQAIESRLHRIPGLAEHFLYLNDDVILGRPITPDLFFTPGGLTKFFPSKAQVDVTPHGPGDRPADSAAKNNRRLIEEAFGRVLTRKMKHTPHPSRRSVIAEIENRFAEQVTATAGHQFRHPDDVSLLSSLQQYYAYLTGRAAKGKIRYLYTDLAQTVTPLRLARLLRGRDVDAFCLNDVDVDSAAVADQEALLADFLPLYLPFPSPFELRTPRPGTTAPAPAIAAPRQPLSGRLTSS
>AP019371.1|BBH64369.1|1154321_1154552_-|hypothetical-protein
MGKAVAFLAALIAGVIVVGWVVSSLLGGFLYYLIVGALVVGGGAWLYSRLKRELAPGTRTQRRIEAAAKTYRMRNR
>AP019371.1|BBH64368.1|1152719_1154258_-|signal-recognition-particle-protein
MFDTLSDRLSGIFTKLRGKGKLTDADIDATAREIRLALLEADVALPVVKSFIASLKERARGAEVSQALNPAQQIIKIVHEELITILGGEGRRLQFAKQPPTVIMLAGLQGSGKTTLAGKLSRWLKGQGHQPLLVAADLQRPNAVNQLQVLAGRAGVDVYAPQPGNGVGDPVQVAKDSIEHARRTAKDIVIVDTAGRLGIDAEMMQQAADIRAAVDPDEVIFVIDAMVGQDAVQTAEAFRDGVGITGVVLSKLDGDARGGAALSVRHVTGQPILFASTGEKLEDFDVFHPDRMASRILGMGDVLTLIETAEAAFDEDQKEKMTSKLLGGEQFTLEDFLDQLIAVRRMGPIANILGMMPGMGQMKDQLAELDDSHFDRVTAIIRSMTPQERTTPKIINASRRLRIANGSGVTVMDVNQLLNRFTDAQKMMKQMSGMMGLPGGRRKATKSPKNKRKGTKSGNRPRVGGAGGGMPGGMPQLPPGLDPSALAGGGMPPGFKLPKLDFNKLNKPKDDK
>AP019371.1|BBH64367.1|1151617_1152694_-|amidohydrolase
MALHVRGTVLPDGEVRDIWLVGDRVTYEPVAGAETISDGGFVLPGLVDAHCHLGIAYGAKPIESVDQARDLAVVDRDAGVLALRDAGSPYPYPELDDEPGVPRLARAGRHVAAPRRYLRDIGVEVAGDEVAAAVTEQAKAGTGWVKLVGDWIDRSVGDLAPSWDAGTMAAAVEAAHAAGARAAVHTFSEEGVEIMVKAGVDSVEHGTGLSLDLIDEMARRKTALVPTMINIRTFGKIADSARGKFDGYADHMIKLRDRFPSVVLAAHEAGVPIYVGTDAGGGIRHGLAAEEMLYLHEAGIPAEDVLASASWRAREWLGFPGLVEGGLADLVVYDTDPRVDLRVVRAPRRIVLRGAVVK
>AP019371.1|BBH64366.1|1150206_1151616_+|hypothetical-protein
MSVDLDEMFADLSRDGDMVPVGPAEGARRRGARRSRNRVVAAALAILLVAGGAGAVVWQRGHRAEPVLPATPNSPIRGLQPLGDPLDAGAGRTWHYTAASEGRLFAVSVPSAASVDARENRGFAADERTGDPLWSTPAELGGTDVPVPIPGTVLLREAAPRPIMHLLDPATGTERWSLPHALDDQLVFHPDVLVRMHDADGMTEGLDIRTGARLWSAPAGADRPRWTSGISAADGTRRWSPAGNDEFSDGYLFQQLASGRMVIRDVRTGEVRNSIAKVLSDQSGYTTVHDGSVVWPVGNEIRAAALGDDSTARVIYTYEEGQEFQGLFGCGQGRICVSLGSPDGRLVAVDIASARELWSAKTSGTTGGAGSRSGRTLTIGMRGAMLHDADGRVLYEGGSQIGWIDDANLLEFDAGPVAVLVSAADGTRTVLGEVPGATVRPGAGADCAWSTETLACADGSLLRRYRFVR
>AP019371.1|BBH64365.1|1149713_1150217_+|RNA-polymerase-sigma24-factor
MTGTDDFDAFYRDTSRRLTRYAYGLTGDSGEAQDLVQEAYARAWQRWRRVSAYEDPEAWLRLIVNRLSTDRWRRIFRRRDHAAAQPPEPPFPPPSENTVLLVRAMRDLPAAHRQALVLHYLMDRSIAEIATETGASTGTVKSWLSRGRAGLAAAIGNDSREGANNVR
>AP019371.1|BBH64364.1|1148268_1149660_+|hypothetical-protein
MFEAAGRHADTYPLAELTEVRRRGARRKRIRAAVASGAAVLVILAGAGVVWQRRHAEPILPATTPARVRGMEPVGEPLRAPAGSTWDTARVAGDRGYGLTTSPDSRVYATGAASWVSESFGELGYDEGPIAAPETLIVRTGTALLFHDPGTGTRRWELPTGGDDRFELYTGLIVRIDGGSHAVEAFDVVTGARLWSVPPGDDRPAELAGMRTAADPGEIDPAGGGPFGQTKFAKAFPLTGDRLAVVTTGGVVAIRDVRTGELVSSVPAAPAMPGTAVAYDGVVYTVSRAGDGTREVHATGATSSRVVFGDRRAFTGSFPCGTARLCVYEQRDSGTYLLVVDAADGRVVRETPFPYDPGVSSARLGRIVVSTTSGTGQRTVILGADGRVLADVPGVGGFIDDGNVLALVRDDATGRFTAVGISAVDGRQIPLGTMPEISGRCDWSADRLACPAGSELWTWRFVR
>AP019371.1|BBH64363.1|1147760_1148258_+|RNA-polymerase-sigma24-factor
MKVDFDVFYRDTSRRLMRYAYGLTGDPGEAQDLVQEAYARAWQRWRRVSAYEDPEAWLRLVVNRLSTDRWRRLFVRRDHAAAQLPGPSVPPPSEDVVLLVRAMRTLPAAHRRALALHYLLDRSVADIAEETGATTSTVKSWLFRGRAGLAAALGLDSPEGVRRVR
>AP019371.1|BBH64362.1|1146290_1147697_-|proline--tRNA-ligase
MARVLTPRAEDFPRWYQDLIAKAQLADNGPVRGTMVIRPVGYAIWERMQADMDARIKAAGVQNAYFPLFIPENYLRREADHVEGFSPELAVVTHAGGKELAEPLVVRPTSETVIGEFMAKWVDSYRDLPLLLNQWANVVRWELRPRTFLRTTEFLWQEGHTAHATEQDAREHARDIHHNVYQAFMEEILAIPVIPGRKTKGERFAGATNTMTVEAMMRDGKALQMGTSHELGQNFAKAFDITYSSADRTVEHAWTTSWGTSTRMLGGLIMVHGDDNGLRLPPRLAPIQVQIMVVKAGEGVTEAAVKLSEELKTAGVRVKLDDRADIPFGRRAVDAELQGIPIRVEVGPRDLATGNVTVARRIDGSKSPIPLADVVGAVTSALKADQQRMFDDALAFRVEHTVDVKTLGEAIEASQTGFARVPWSAVGEAGEKEANGKAVTVRCLTREDGSMPESDDEPDLIAYLGRSY
>AP019371.1|BBH64372.1|1158597_1161066_-|hypothetical-protein
MRRLHTTPDAYGTELLERQWLEMCGPSPSSDGPATAALHTRSASARAVLAYAAARRSVDDLILGAYEGRLFPDADPWTFGELARVVALQDLWSEDRADAMVLLDSLLRTFGAAGVAPRHQGLHAQLAYATGDRTRTEKLLADYPEIPDPVRTALVVDLTTAEDWLPRFLGLLPAPGFTLDGEIGPRFDRIRSRPAARAGSAHRITTIVTTYRPGLALLTTVRSLVAQSWTNHEILVVDDGSGPGHDAVLARAAALDPRVRILRIPQNGGTYLARNAGLDAATGEFVTFQDSDDWSHPLRLERQAAPLIADSALFATTSAGIRVTEDLVVTRPGIPEYRSYNLSSLMIRREPALARVGYLDTVRKGADAEYVERARAVFGRPAIHHLGGEPLALIRLSGGSLSSADISPGWMHPARYAYMSAFKAWHRDVAAGRADAVRPRDIGVPRPFAAPRRLTLRPLDRDAPRQLTATADTHDYDLILAADWSRQEGMTRPMGERLCAAAVPGRRVAVLHLSLLRHVTGKPADLDPSVQSLINSGRVGQVMLSDDIIARLVIVQDPALVAFAPGYPSSIRADRVVIEADPAWGDAAFHCEAEARRLFGVEPWWAPAGAADRRQLAGGPFGIRLAKADLPGTIDPERWRLHRTGPRADRPVIGRMLFDRPGATVAAEWLRLREALPASGGLDVRVLAPVGEMRLPKNWLVYRPSDVAARAFLHQIDFYLHLPADDRTTILDPELLAALAAGCVPVLPHRFRPLLGPAALYCEPDEVVPAVSRLHRRPDALAAQSRRGLDLVRLEHHHGRFAAALDTLLMPDLPPMPALPSA
>AP019371.1|BBH64373.1|1161193_1163386_+|antifreeze-protein,-type-I
MTEHVHDVAILSDFRYPGGTSASIAAEVRAQARAGLSTVLVQVRSPHLKRDRPFNPLIVELLKDGSAHLAVEGEQTRAKLFVLRQPRIFTDDLAAPPRVTAERTVMVLNQAPGDAADPARYYDFAEVRARIEGHFGTAIEWAPISPQVRTEVLRSAPDAPLTPTDWHEIIDVAEWWDERPGPLGPVPVIGRHGRPDPVKWPRTTEELLLAYPDDPGVKVRVLGGGELAVERLGRTPAGWDVVEFGTAPPREFLGTIDFFVYFHDPDLVEAFGRTIMEAMAAGVPVLIGEHFRPIFGDAALYTTPAGVLPLVGELHADPRRYREVARRARDFVESRFGYASHEARLADRGVRPPGPGTEVELHRPLVTSRRSRGVLMVSDNGVGLGHLSRLMAIGRRLPEDIRTVIATQSHGASVAHREGFLTEYIPSRSVLKLPRQRWTEMLTSRLEHLVDLHEPAVVAVDSVPHDGIVAAVKARPDITWVWVRRPMWRRDTGAEWIERGGYFDAILEPGEFAAAADEGPTVQDRAGVHTVDPITYLDAEELAEPAAARRALGLDPGRPAALLQLGAGNINDIASPVARIAGHLRRAGFQVVLAESAIATEPMPPVAGAHLVKLYPISRYLRGLDLVISASGYNSFHELLAFGVPAVFVPNRETSLDDQVSRARFAAAAGAALIVEDPETEELDRVLAQAVRDDVRERLRDRCAEVGPGNGAAAAARWLSELADRRTTGV
>AP019371.1|BBH64374.1|1163388_1164039_+|hypothetical-protein
MPDTPAELTDPAKVDALVVRLRTIEQQRDAWQSRFETVAGERDEQRETVRRLRASGSYRLGRTLVSLARSPLSTSRKLVRRKPARRKKTPPPPLPTHLYVAIGLDLAALRDFVLAVRRRLLVENDHRAVVLTDEPAFSLLRKAGLVLEYLPDRLTWQKHRPDRPWDAVLAERLAHLSRDHAAAQVIFVDPDAPLSLADLLAEIDTTEPGQPSLPQS
>AP019371.1|BBH64375.1|1164050_1165634_+|hypothetical-protein
MTLPQQSAGRDISPSSADSPADEAAGRGLWGHVLRRCVLVPLIVLTPLLGVAPRGDHRFNIYWHGGMFLDHPLRIVSHTIGTGETYLRLGNFRPLGRMLEKALDTLVLVGAEQLHLSPAIMLRVVTAGAAVLLTLALVIFAESLLTRGPLFGSAPSLVALLLPYAVAGAFVAAGRNSTTTLFGGLYLSTTAVVLLVAAATCRLERLRWWHAVLAVTTGGALAVVNEPAYFAVPLATVAVLVRGWFVTGRRGRDLLRSAGVRLAVLLWAGFLPVFGIVRWIIRGYCADGGCYHGSDIAVDGRSLLIMPARMLAWLPPAQWEAATAKTPGDWLWGVVPLVGLGLIALLGLRTIKALKRVKRPGAGSLTGLAIAAAALLVFGALPAALSVEVHDYFDMRALLTEGWRDSAVTAPAGMLLALAVALLITRRSFVPVLLGVFVMCAAVSATANRAYADASASWASSQLDNRIAQSVGGFERSTAGNARRCALLTEALRELSGEPARQKRLTESLDAAAHALAGVPYCAGGSR
>AP019371.1|BBH64376.1|1165630_1166605_+|glycosyltransferase
MNDPLISVVSPIFNEGEGVDRFVATLDEVLSGAGLRYELVLVDDGSVDDSWSRIAHLSRLDQRVRGVRLSRNFGKEAALLAGLEQAGGDAIVVIDSDLQHPPSVIPAMVRRWRDGAHVVEAVKRNRTGQSLGNRLSSRVFNSAFTGLTKVDLVNATDFRLLGRPALDALRQMPEHSSFFRGTSSWIGFTRATVEIDIDHRFGGASRWTLRGLFRLAVNGLTSFTSAPLHLVTLAGIGFALFSVVLGVQTLVRWISGGSVAGFTTVILLLLVTGTFVLLGLGVIGEYLARIHEEVRRRPRYLIQERSTAGPAVPEQWVAEQHAER
>AP019371.1|BBH64377.1|1166591_1166978_+|hypothetical-protein
MPSGEVLGRLIRYGISGGLSALTHFGVGLAGVQAGLVPVVASGVGFAASVVVSYVLQRAWVFRSSRRHGVAGPRFLAVTGLAFSVNTVVLWVGSSVLHGPYAAVQAVAIVLIPVLNYAVNSRWTFAPV
>AP019371.1|BBH64378.1|1167149_1169207_-|acyltransferase
MTTTLSRPDVRPVPAAAPPRHRHRADIEGLRAVAVLLVVLAHVGVPGVAGGFVGVDVFFVISGFLITSLLRTELLSTGRLDLPRFYARRAVRLLPLATLVIVSTLATVWFTAPPTRFGGYAADAVGAATYTMNLRLADAGTDYFADQAPSPFQHFWSLAVEEQFYLVWPVLIGLLAFWGRRRRWLPGAVLTLGTLSSFAWSAHELGRAVPWAYFGSASRAWELGAGALLALLMTGLHRRRRWLAWLGLAAVVAAALVYDETTPFPGPAALLPVLGTIAVIAGGGNRLLETFPMRWIGRMSYGWYLWHWPLLFLAPGGLWMRAAVAAGALGLAAVSHHLLENPVRHHRFWLPYPRRGLGLGFALSAVAAGLAALGMIFPPLVPTGDAVPDTRKVMARAVDPAGELKQMVAAAQSAGNVPENLTPAFETAAGERSAPQEEGCHVGLTGPFKPTSSCAYAAVDADRTVVLFGDSHALQWFPAMEELARRRDWRLMVYTRSACSPADLELQERRSQSRYAACDTWRRQILRKIGRLDPDLVVVSSSVNYRALLTGDPADPEAVWRSGWQRTLTALQRSAGSVAILGDTPFLAGDPADCLATRPAAIGTCAPPADMVVLEPGWRAIQRATANALKVPTVDPLPWLCAERCPLVVGNRLVYRDSNHLTSAYAKLVAPLLDPKLPWKPRAVR
>AP019371.1|BBH64379.1|1169210_1170257_-|hypothetical-protein
MSSLTRIGRRAVRRLPSLSGRQAVAVCGAAVLCAGVAAAALTGYDRVATALLGLLAGVTVVVLLAVLRRLSGVQKAGLAAQRDLRTTVEEMQRRLVAAVERERLTAGDRHLELSEAVARVKQVMDRKASSAQVLGLPRELEATVQLFQGFVPRAPMPSSGDWALNPTDLLELLHLIRIRQPRLVLELGSGTSSVWIAYALEQSGGRLISLDHDAEFARRTRSVLAAHGLTGVAEVRDAPLTPASIDGRDYPWYDPETLADLHDIDFVLIDGPPAAVGEGARYPALHMIEKRLADRATLVFDDAGRKDEQAAIAAWTERFEGLTREGEILGRHAVLAFARPPAMAAAHG
>AP019371.1|BBH64380.1|1170313_1172779_-|hypothetical-protein
MAEAQPVALLDDHVTLAGAGAELSLPHTAMRNRSVAARRVLARAAAGGSPKGGTLDEFLEAARSGDTRPLRGFRRRVDPALLAGLAQTIALQDELPGDREDALALYALIRTGLGARAVPPAHQALHAQLAYAWQGPAQARDLLAAYRRIPTPARETLEIDLANPYAGGSVPEETWLARFGRLFPAPGPGLIAAPERLPFDRLTTGPATPVEADQRVTVVVTAFRPGVGLITAVRSIAAQTWRNLEILVVDDASPPEYDAVLAEAESLDDRVRVLRLAENSGTYAARNAGVEAAHGEFVTFQDSDDWSHPRRVELQVRPLLQRSEVVATTSEGISVTDQLVMTRPGIRRGRVNVSSLLFRREAVTRRIGCFDRVRKAADSEFMERIEAAFGPGSVRKVAKPLALIRLSEGSLSRAEIRAYWMHPARTAYMSAYRCWHASGEPLRQDPGTRDRPFVAPPHLTGGSAAPGWDVVVAADWRFLAGSQRAALAEVRALRRAGLSVAIMHLESLRSVHRQRRLLSPGVQRLINTGQVTQVLESDRIEAGLLVIRQPEVLQFAPEGGCGLRPRRVLVVADRAPARPDGSDRRYTVEAGSEAVRRLFGVDPLWCPQDPGVRAALAGADLTEFDLSMTVEPEDVRRPLPDRAGPPVVGVDLCDAGEWPADLAAILAVPKRCRGADVRVRLPENPLRPGTLPVSWLVYEAGDLDPRTFVAQLDFYCHFPSDDAPELLSRPALEAAATGCVVFVPERLGEAYGDAAVACAAADVPKLIRRFQNEPRRYAEQSRRARAAIARDHRPDALADRIGALARPPAGTPSQRVPGAGA
>AP019371.1|BBH64381.1|1172853_1175124_-|bifunctional-uridylyltransferase/uridylyl-removing-enzyme
MTNPLSEPPAPPARPAAGGSLDKLRDHIGAAARDERAAALDVWLKDLFPSHVPGVSLLAVGGLGRRDCAPYSDLDLVLVHNGTAGIDRIASGLWYPIWDARLGLDHSVRTLPEALSVAHDDVKVALGLLDARHVAGDPTLSAEMIAATGDQWRRTAVRLLPQLRELTTARWTQHGELAFLLEGDLKEAAGGLRDLTLLRGIGRAGIADTMRPAVRAAGLRLLDTRDALHLAVGRRVDRLVAQERAAVADLLDLEDADALLRRVSGDARTIAHAVDDAWRAVDRLRSGRRRGSTPAVPSRRPVARDVVEQDGELVLARTAIGPVPDPSLSLRVAAAAAIVQLPIARATSEWLAAFCPPLPTPWPPAARAALISLLGSGPGLLPAWETCDRYGLIDAWLPEWARMRSLPQHHPIHRYTLDRHLVQAAYEATRFTREVDRPDLLLLGAFLHDVGKGLPGDHSIVGAPIAAEIAGRIGLPAADVATIEKVVRLHLLLPDVATRRDLSDPLTISTVAEAVGDPATLDLLHALARADSQATGPAAWSDWKGRLMAELVRRVHTAMDTGELPEPPQPDPELLEGGLPVVHLDGDRVAVAAADRRGLLAGVTACLAMHRLDVVAANTATVDGRAIVEFYTSPRYGSPYDPVALAADLRRVASGDVSVTQRVRARAMSARGGTASPRVVWQRAAATDAAVLELRAADSAGLLYRVTAALDEAGAEIRAARISTLGGDVVDAFYLVGTWADSAERNRVEAAVLSAV

Crispr_ID: AP019371_2

• CRISPR_ID: AP019371_2
• CRISPR_location: 2499592-2499690
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of AP019371_2

Consensus_repeat	Method
GTGGATCGCGGTGGCCCGTGCGG	CRISPRCasFinder

spacers of AP019371_2

>2.1|2499615|15|AP019371|CRISPRCasFinder
ATCGCGCCTGTTGGC
>2.2|2499653|15|AP019371|CRISPRCasFinder
GCAGCGCTTGCTCGT

CRISPR arrays and Neighbor proteins around AP019371_2

CRISPR arrays

The CRISPR arrays of AP019371_2

>merge|AP019371|2|2499592-2499690|CRISPRCasFinder
CGTGATCGCGCCTGCCTGTGCGGATCGCGCCTGTTGGCGTGGATCGCGGTGGCCCGTGCGGGCAGCGCTTGCTCGTGCGGATCGCGCCTGCTCGTGCGG

>AP019371|2|2|2499592-2499690|CRISPRCasFinder
CGTGATCGCGCCTGCCTGTGCGG	ATCGCGCCTGTTGGC
GTGGATCGCGGTGGCCCGTGCGG	GCAGCGCTTGCTCGT
GCGGATCGCGCCTGCTCGTGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH65626.1|2500647_2501205_-|hypothetical-protein	unknown	unknown	gnl|CDD|223340
AP019371.1|BBH65623.1|2496082_2498149_-|oligopeptidase-B	unknown	unknown	gnl|CDD|224684
AP019371.1|BBH65629.1|2507828_2508377_+|hypothetical-protein	unknown	unknown	gnl|CDD|381147
AP019371.1|BBH65628.1|2503377_2507781_+|histidine-kinase	unknown	unknown	gnl|CDD|237951
AP019371.1|BBH65621.1|2493712_2494399_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
AP019371.1|BBH65617.1|2489182_2490199_+|hypothetical-protein	unknown	unknown	gnl|CDD|340411
AP019371.1|BBH65634.1|2512134_2513478_+|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl|CDD|234607
AP019371.1|BBH65622.1|2494395_2495943_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH65615.1|2488350_2488770_+|anti-sigma-factor-antagonist	unknown	unknown	gnl|CDD|132912
AP019371.1|BBH65633.1|2511680_2512166_-|hypothetical-protein	unknown	unknown	gnl|CDD|132914
AP019371.1|BBH65624.1|2498285_2499404_+|glycolate-oxidase	unknown	unknown	gnl|CDD|223354
AP019371.1|BBH65618.1|2490195_2491551_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
AP019371.1|BBH65625.1|2499910_2500525_-|hypothetical-protein	unknown	unknown	gnl|CDD|223340
AP019371.1|BBH65630.1|2508485_2510009_+|hypothetical-protein	unknown	unknown	gnl|CDD|367395
AP019371.1|BBH65620.1|2493179_2493716_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
AP019371.1|BBH65619.1|2491543_2493115_+|hypothetical-protein	unknown	unknown	gnl|CDD|369272
AP019371.1|BBH65632.1|2511154_2511349_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH65616.1|2488766_2489171_+|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|340411
AP019371.1|BBH65627.1|2501237_2503148_-|hypothetical-protein	unknown	unknown	gnl|CDD|225118
AP019371.1|BBH65631.1|2510112_2510943_+|hypothetical-protein	unknown	unknown	gnl|CDD|237874

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH65626.1|2500647_2501205_-|hypothetical-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	5.56553e-20
AP019371.1|BBH65623.1|2496082_2498149_-|oligopeptidase-B	gnl|CDD|224684	COG1770, PtrB, Protease II [Amino acid transport and metabolism].	0
AP019371.1|BBH65629.1|2507828_2508377_+|hypothetical-protein	gnl|CDD|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.66726e-31
AP019371.1|BBH65628.1|2503377_2507781_+|histidine-kinase	gnl|CDD|237951	PRK15347, PRK15347, two component system sensor kinase.	1.54325e-69
AP019371.1|BBH65621.1|2493712_2494399_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	4.25735e-92
AP019371.1|BBH65617.1|2489182_2490199_+|hypothetical-protein	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	2.93343e-27
AP019371.1|BBH65634.1|2512134_2513478_+|glutamate-1-semialdehyde-2,1-aminomutase	gnl|CDD|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
AP019371.1|BBH65615.1|2488350_2488770_+|anti-sigma-factor-antagonist	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	1.01776e-30
AP019371.1|BBH65633.1|2511680_2512166_-|hypothetical-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.55858e-20
AP019371.1|BBH65624.1|2498285_2499404_+|glycolate-oxidase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.10312e-20
AP019371.1|BBH65618.1|2490195_2491551_+|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.49767e-54
AP019371.1|BBH65625.1|2499910_2500525_-|hypothetical-protein	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	7.59173e-15
AP019371.1|BBH65630.1|2508485_2510009_+|hypothetical-protein	gnl|CDD|367395	pfam03211, Pectate_lyase, Pectate lyase.	4.97827e-102
AP019371.1|BBH65620.1|2493179_2493716_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.31359e-18
AP019371.1|BBH65619.1|2491543_2493115_+|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.40124e-43
AP019371.1|BBH65616.1|2488766_2489171_+|anti-sigma-regulatory-factor	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	5.60491e-41
AP019371.1|BBH65627.1|2501237_2503148_-|hypothetical-protein	gnl|CDD|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	1.62271e-37
AP019371.1|BBH65631.1|2510112_2510943_+|hypothetical-protein	gnl|CDD|237874	PRK14971, PRK14971, DNA polymerase III subunit gamma/tau.	1.73284e-06

Protein sequences

>AP019371.1|BBH65624.1|2498285_2499404_+|glycolate-oxidase
MTDSLLDALVDICGPGFARPARSVDRIAGRQAAHVAVPATASAVADTLRLSDSFRVRGAGTKIDWGFPPADLDLIVDTGRLNGLWDHNEATAVVAAGTPVAAVQAALALRGQRLAVDPPSRGATIGGMLAVNESGPLRHRFGSPAAQTVSVDYVTASGAVESSDGEGGRPGIAEIDGVLTSAVLRLEPLPPARRFVGRTVETPAEVDELVSAVLAQDVSPSAIEVDLPGATGGVLALLLEGHESEVAGSADKIAGVWGGRSVVTSAAPSWWGQYPFQASSDVALRIAAQPRHLQAVAYSLRDAAGSAVAIRGSAGVGTVHAVLPSSLGVARVREILVALEQVLLARRGKLAVVSAPPELAVELPMADRRGLF
>AP019371.1|BBH65623.1|2496082_2498149_-|oligopeptidase-B
MTNEAPPTAHQSPTERTFHGDTVTDEFAWLMDKEDPATIAYLEAENAWTERATAHLDDLRQKVFQEIRSRTQETDLSVPSRKGAFWYYTRTVEGKQYGIHCRVAVKPGEVDPPMGADKPGEQVLLDGNELAAGKEFFALGTFDVSPDGNLLAFSTDFAGDERFTLKIKDLRTGEILPDEVTDAFYGSAWSADGSVLFYITVDEAWRPYRVWRHTVGASTEDTLVYEEPDERFWVGVDLSRSEKFIVVDTQSKITSEVRVIPSDHPTAEPALIAERVQGVEYSVEHHGHRFLILHNRDAEDFALACTSVDNPGEWVELIPHQPGTRLESVDAFARHVVVSLRRDGLTGLRVMTDGSTDTYDMTFPEPIYSVGLAGNPEYETGSIRISYTSLVTPDSVYDVDLVTRAMTLRKQKPVLGGYDPADYEQFREWATAPDGTRVPISIVARRGLVKNGDNPALLYGYGSYEHSIDPYFSIARLSLLDRGVVFAIAHVRGGGELGRGWYENGKMLAKKNTFTDFVACAEALVRARWTSASRLVARGGSAGGLLMGAIANLAPEAFAGIVAEVPFVDPLTSILDPSLPLTVTEWEEWGNPLESAEVYAYMKSYSPYENVAKLSYPKILAVTSLNDTRVLYHEPTKWVARLRAVAPDGEFLLKTEMGAGHGGPSGRYDAWKEEAFVLSWILDVVKAA
>AP019371.1|BBH65622.1|2494395_2495943_+|hypothetical-protein
MRFSTLVRLSLAGNRTDRLRTVLTAVSAALAAVFLLAAATVASIRGGEMVIDGTGMGTRSPGTQQYASALLMEAGLRPGVIFALVMLALPVLALAGQCIRLGAPARDRRLVALRLGGATPGQAVLIAGAETAVASLFGSLIGLGVFAALRSVLDNRTADGRLWLPVDVVPDPLLVAGALLLVPLLAGAVGVLLMRRMVITPLGVVRRVREDGPGPWPGFLIAAGLVAFVSPGLLADLLPVHGEFPSWVAPVLMGGGVLLVTVGVVIGVGWISYTSGRLLRRYGRGAATLLAGGRLMADPWNGSRTLGALLGAIVFGAGTLGFRAMFATEFAASARYEEMIAGTGYPTSGYSDPEFYLGAIRLVMIAVSIAMLVAAGGVLVALVEGIVARRRAYAALTATGVPRRTLSAVLLWHTFVPLVPAVLLALGTGASLFRLGATEVRLGEPFEQCIDPAAVDWETCARETIVPPSLVVPIPIPFAQLALLGGGALVAMLLVVGVGVAVLRTSTDLEELRVG
>AP019371.1|BBH65621.1|2493712_2494399_+|ABC-transporter-ATP-binding-protein
MTEALLTATGVHKKYGNTPALRGVDFSIESGEIVAVTGPSGCGKSTLLHCLAGLLSLDAGEVRYRDQDIGLFSEASRSRLRRSDFGVLFQFGQLVPELTAAENVGLPLLLAGSGRREAREAALGWLDRFGVADLADKRPGAVSGGQQQRIAAARALVTEPQVIFADEPTGALDQLSGEQVLGAMVQVVREQGTAVVLVTHEATIAAYADREVVLRDGAVDPTGLGVTP
>AP019371.1|BBH65620.1|2493179_2493716_+|PadR-family-transcriptional-regulator
MSTAHVLLGLLVAGPRHGYDLKRAHDERLPQAKPLAYGQVYSTLGRLERDGLVEQSGQEQEGGPERTSYSLTDLGRKRLDAWLTEVEPPAPHVTSALFSKVVVALLAADADRARQYLTVQRAAHMTRMRELTVAKSSPGTTVGDVIAADYAIGHLDADLRWLQTTMARVADLQKEVTA
>AP019371.1|BBH65619.1|2491543_2493115_+|hypothetical-protein
MSDLVRSGLQNRGPATVLVVDDSATKRYLLVSWLTRAGFTVIEAETGGAALTKLLDTEADLVVLDVKLPDMSGFEVCERIKTDQRYGVLPVIHVSAHAVDVNDRTQGLNRGADAYLVEPIEPEELIATAQAVLRYYRARRRAELLAERMVRLAEATLAINSAPTLPTLLEAAAEGAHAIFGGPVAVVAETSEGESLAATGTPAKVRPWAVPALDHPVAVGSLVRTDEAADWNVAEWPEGETVAVAAARLRADRPPVYVAAPGSSQNPGFPVLRQLSQAVAAAVEAQRSFDEEHRIAVTLQRSLLQSELPRVPGVELAVRYEPAGAQTEVGGDFYELTVLGGELLVAIGDVAGHSLHAATVMAELRHAVRAYAVEGHPPGAVLELVNRFMRTVLPHDSATLCLLTMDPATGRIRMASAGHLPPLVHVNGEATFLSPRGPLLGIDAPRRAELELTLPPGGTLVLYTDGLIERRDADIDVGLQALAAIASEVEPDLDAFCSRLLSRLAGPGEQADDIAVVALRRTA
>AP019371.1|BBH65618.1|2490195_2491551_+|sensor-histidine-kinase
MTYTAGEQLISMRLRVEQDIFAIRQLGREVARVVGLESQDQTRFATAISEVGRVLLAAGPDAEVRFSVRPYGVPTLQVTMAHPSAGETSRLAGQLRQVGRLVDTMEVDDGSTGTVVRMARRLPAAAPELTPARMDEIRTGLAGHVPGSPLDELAVQNQQLIAALDEVRAQRDDLARLNAELEETNRGVMALYHQLSEELEETNRGVVALYAELDEKSVQLRAASEAKSRFLANVSHELRAPVTAIIGLGRLLTDSGSDELTEEQGRQVELIRTSASDLLTLVNGLLDLAKAEAGRIEPNWSDVDLKAMFGQLRGTLRPLATRPEVDFVVDEPTVPSLRSDEVLLAQVLRNLLTNALKFTESGSVRLSVRRVDGDVEFAVADTGTGIPPELHERVFEEFYQVPGSKPVSGKGTGLGLPYARRLAGILGGGLWVDSLPGAGSTFTLRLPATHE
>AP019371.1|BBH65617.1|2489182_2490199_+|hypothetical-protein
MASLPEGLLDDGVWFRVEEAVTAAAVRRAAERLAADLGMPERSIADLSIVAAEAAGNLVKHADQGQILVRAVRTPEQAGVEIIAIDSGPGIDDVSRAIGDGHSTAGTLGIGLGAILRQASRWDLHSLPGRGTVLAVQVWPAEPPAPAWAGGLIRPLPGESVSGDAYAVRQEGDRRQVLVSDGLGHGGLAAAASQEAVRTFLKGPITPPAAAVEALHRALGHTRGAALAVAELDTGAGEVRYAGLGNISGTVLAPDGTRRGMISMPGIAGHQRRQVREYAYPLEPGAVVLMHTDGVQDRWNVSDYPGLITRSPEVIAATMLRDAGTRRDDAGVLVARPS
>AP019371.1|BBH65616.1|2488766_2489171_+|anti-sigma-regulatory-factor
MSEESQRLPVSTDQDVVRVRQLVRTVSVAVKLSLVDQTKLVTAASELARNTLVYGGGGEVVVSRVQNERRAGIKIVFADEGPGIADLDLALTDGYTTGGGLGLGLSGARRLVDEFDIQTEPGKGTTITVTKWCR
>AP019371.1|BBH65615.1|2488350_2488770_+|anti-sigma-factor-antagonist
MERVPVLKIGDILLVSIQIDMEDQVALQLQEDLAERIVATGCHGVIIDISALDIVDSFVGRTLATIASVSRVLDAETVVVGMRPAVAITLVELGLSLPGIRTALNVELGIEMLARARQDSEIELDFDEDEPDTAAVSTP
>AP019371.1|BBH65625.1|2499910_2500525_-|hypothetical-protein
MAKTQYYTATSIDGFTADQSNSLDWLFEVDEGTANPFGEFFAGIGAFAMGATTYEWVLKNDNLLEEPENWHDMYGDVPCWVFTHRDLPPVPDANVFMISGDVRRVHEAMLVAAQGKNVWLAGGGDLVSQFVDHGLLDEIILGIAPAILGGGAPLLRRKLLVDDLILTGVSEVGQFAYLTYAVGDVARLGRHLAAETVTRIPSFG
>AP019371.1|BBH65626.1|2500647_2501205_-|hypothetical-protein
MKTQYYTATTIDGFIADEHNSLDWLFEVDEGGENPFAEFFAGIGAFAMGSTTYEWILAHEKALDNPEKWLGPYGDTPAWVFSSRDLPVIPGANLHFVRGEVSPIHQEMVSAAQGKNIWLVGGGDLVGQFADQGLLDEVILGVAPVTLGKGAPVLPRRIRSSRLTLTGARPIGQFAYLTYDVSPPI
>AP019371.1|BBH65627.1|2501237_2503148_-|hypothetical-protein
MLEETGLVVLLNEALLLTTELSTNAVVHANTELEIEVAADAAGLTVTVTDFAPGPVEQLAVGPKNESPDIGEVAERGRGLLLVDHFASRWGTVHEGDGKGVWFRLDQRSDGAAAPVRLPQHGETPSLGALTGLLRSGNDRHTDEGLADLAADLLSRLARLTGAAGGVVRLDRGDGMGRQLLARYGRAPRDNADTIRVPLDVHRPYSGELELDASPVGYAQSLATMVAERFSLHLENDRLRRADVRRQTWITFLAEASELLAQSLDVNLTMALIPQLVVPRLGQWCAVHTTDAWGRLQLAAATHAEESQLAQLHTSLAEDGPESILARLEEASRLGTQVMFGTPSEGYAVPLVARGARLGTLAVGRHPKHRHDADEVAVLEDVARRAALAIDNARIHDERRTVARTLQASLLPPALPHVEGIGFAAEYVPTGSEVGGDFYDVVPFGDDQYLVVVGDVSGKGVQAATVTGLVRDVIRILVDDGKAMSEILWRVNRTLVQRGGGRYCTLAMASVTRKGASLAVCLHLAGHDRAVLVRADGKTSFVGEGGTALGLLESITSPDVAITLDPGDSLIFYTDGVTERRRGRELFGSTRLREAAMPLAGYPADVMAARLRSTTINFSVEEPRDDIAILVLRNDA
>AP019371.1|BBH65628.1|2503377_2507781_+|histidine-kinase
MTAANEASVGVPDETVLLGELADALRRVRRGDLKVRLPRRDGTAGAVAEAFNEVVSLQERQNLDMRRISRIVGRDGRLTERLDEEGLDGAWADSVRSVNSLIDDLARPTTEISRVIVAVAEGDLSQHMALEMDGRPLRGEFLRIGRTVNTMVDQLSSFADEVTRVAREVGTEGELGGQADVRGVAGTWKDLTDSVNTMASNLTHQVRSISQVATAMARGDLSQKITVSARGEVAELADTMNGLTDTLRLFAEQVTRVAREVGTEGKLGGQAEVPNVAGTWKDLTDSVNSMASNLTSQVRNIAQVSTAVAKGDLSQKITVAAQGEILELKDTVNTMVDQLSSFADEVTRVAREVGTEGRLGGQAQVRGVSGTWRDLTENVNQLAANLTAQVRNISQVSTAVAKGDLSQKITVDARGEILELKNTVNTMVDQLSSFADEVTRVAREVGSEGKLGGQAQVKGVSGTWRDLTDNVNYMASNLTSQVRNIASVTTAVAKGDLSQKITVDARGEILELKSTVNTMVDQLSSFADEVTRVAREVGTEGKLGGQAQVRGVAGTWRDLTDNVNSMASNLTSQVRNIAQVSTAVAKGDLSQKITVDAQGEILELKSTVNIMVDQLSSFADEVTRVAREVGSEGKLGGQAQVRGVAGTWRDLTDNVNYMASNLTGQVRNIASVTTAVARGDLGQKITVDARGEILELKNTVNTMVDQLSSFADEVTRVAREVGSEGKLGGQAQVKGVSGTWRDLTDNVNQLASTLTIQLRAIAEVSTAVTRGDLTQSIAVEAQGEVAELKDNINQMIVTLRDTTKANAEQGWLDSNLARIGGLLQGQRDVGEVCRMIMTEVTPLVDAQLGAFFLVDNEEAVMRLRLNAAYGYVARDHEVMFGPGEGLVGQAAVSRRTIRVRATHDGILTMRSGLLAMPPNDLVVLPVLFEGEMLGVIEFASVAAFSGLHLTFLERLVANIGIALNTIQANRRTEELLSQSQRLAREMQDQSAELQRTNAELEDKAKLLSDQKANIELKNREIELARLGLEEKAQQLSRANTYKSEFLANMSHELRTPLNSLLLLARLLADNTEQNLSSKQIEFARTIHSAGSDLLSLIDDILDLSKIEAGRMDVEPDVVDFDGIRSYVEQAFAPQAEDKGLEFRVDVAPELPDSIVTDPQRLQQILRNLLSNAVKFTDSGSVTLSIFPASPDVDLDMPSLLSARQVVGFAVTDTGIGISDEKLAIIFEPFQQADGTTTRKYGGTGLGLSISREFAALLGGTITVASVPNGGSTFTLYMPEALAPDAIPMPVLPPVPAKAVSVRPVASLDMPLMEMPQLTSREEVKKPAVTPAGRQLDGATVLIIDDDVRNVFALTSALEMHGLNVLYSDNGVDGVRILAEHPEVDIVLMDAMMPDQDGYETTRGIRRNQRFRDLPVVFLTAKAMPGDRESAIAAGASDYITKPVDLDELIELMARWVNAEGSTASERS
>AP019371.1|BBH65629.1|2507828_2508377_+|hypothetical-protein
MGERAKALLVDDRRDNLLALEAILQGLPVTAVAVESGEAALKQLLTDDFAVILLDAHMPNMDGFETASHIKRRERTRHVPILFLTAADRDAQLALRGYAVGAVDYLTKPFDPWVLRAKVSIFVELWTKNQQLKAQAEASREREAQWQRLTETMDEAARVLRAGGEDAAAEVLDLLEKARWGS
>AP019371.1|BBH65630.1|2508485_2510009_+|hypothetical-protein
MRHAMPPTASDRRRRRRLVTGLGAAGAAGAVTALVAVLVPSASASTLFSDDFESGASGWSKSGGTWAVATDGSKVYQQSKADSELARVFAGETSWTDYSVQAKVKPVTIGSGLAGIAARASSASTMYRLALTSAGKAELQSVKGSTVSVLGSVAVSNLTTWHTLRIDASGSTVTGYVDGAKVATGTGTLAGTGRIGLVTSYASASFDDVAVGPVTAATATATASPSVSKTASPTASPSASKTATASASPSASKTATASASPSTSKTATATPTTTSTGTSPTASWPTATGTKPVTATIAVSGTLDGGNVRYYGSGALGDDSQDEGQDPLFKLADGAVLKNVILGAPAADGVHCSGSCTLINVWWENVGEDAATFKGGTSATYTVDGGGAKSADDKVFQHNGGGTLTIKNFQVADFGKLYRSCGNCSTQYKRAVVVQNVIATAPAKSLVGVNANYGDTATLSKVTIVGDDDLDICVRFTGNNTGKEPTKIGSGADGVTCKYAESDVTYK
>AP019371.1|BBH65631.1|2510112_2510943_+|hypothetical-protein
MRLIEDDLRAALRAEAVRHRPDRDAMLDRITQTAMRNQFARHRKASPRLRISGAAVAVAAVLGGGGFAQWALAGDGTPPPAPPAPSVSVSVTPSDAPSSPSASASPSDLPSTATSTSPPARRPRSAPASPSSPPSSAPGVAPADTPRDTTTSGPLWSDGSIDASGAQGTGVVTVKTTEKLTALDVTIRVTRTPELVSRGGSQQVPGASVTSTVTEEPDALLYRFVLSSGDVLEPGTYVFYARYTYAEGGRDAGGDTYAATAATEQGETATVTGAFG
>AP019371.1|BBH65632.1|2511154_2511349_+|hypothetical-protein
MCGHRPVEGGQGTQWCGVCGHRPVEGGQGTQWCGVCGHRPARGGQGTQRRYVCGHRPVEGGRRT
>AP019371.1|BBH65633.1|2511680_2512166_-|hypothetical-protein
MGYVVVTAVPILSAAYGECLERVAHVLGRCPDTPDLTTPDGPNRPREDRLTCVERPELSIAVQRAPDEVVIQLAGEIDVLTVTELSTIVNDLLGAEPLSRIVLDMAGVTFCDSQGLGTLVVLSRKAQHAQTVLALANVGDFLMRVLDITGLRSALMISSTA
>AP019371.1|BBH65634.1|2512134_2513478_+|glutamate-1-semialdehyde-2,1-aminomutase
MGTAVTTTYPTADLPYPEDAPVSQALFDRAQAIVPGGVNSPVRAFRAVGGTPRFMVSGSGPWMTDADGRRYVDLVCSWGPLIHGHAHPEIIEAVQRAAASGTSFGTPTAGEVDLAEEIVRRTAVDEVRLVNSGTEATMTAIRLARGFTGRSKIVKFAGCYHGHVDALLAAAGSGVATLGLPDSPGVTGAAAAETIVVPYNDVAAVERAFEIDGADIAAIITEAAPGNMGVIFPKDDFNGKLAEIAHRHGALLIVDEVMTGFRVSAGGWNGLHPVDADLFTFGKVMGGGLPAAAFGGRREIMSRLAPAGPVYQAGTLSGNPLACAAGLASLRLADDATYKRLDELAGTIGSLASAELGKAGVPHRLSSAGNMFSIFFTDAEVVDYDSAKTQDAAAFKAFFHTMLSRGVYLPPSAFESWFVSTAIDDAALEQIASALPHAARAAAGSAK

Crispr_ID: AP019371_5

• CRISPR_ID: AP019371_5
• CRISPR_location: 3791330-3791571
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of AP019371_5

Consensus_repeat	Method
GGGGCGGTGGGCGCACGC	PILER-CR

spacers of AP019371_5

>5.1|3791348|42|AP019371|PILER-CR
GGACGTGTGTTGTGTGCGCTGGTGGCCCGGGTCGGGGCGAGA
>5.2|3791408|34|AP019371|PILER-CR
AGTGTTTGGTTTGCGTGAGCTGGGCGCCGTGCTG
>5.3|3791460|42|AP019371|PILER-CR
GGACGTGTGTTGTGTGCGCTGGTGGCCCGGGTCGGGGCGAGA
>5.4|3791520|34|AP019371|PILER-CR
AGTGTTCGGTTTGCGTGAGCTGGGCGCCGTCCTG

CRISPR arrays and Neighbor proteins around AP019371_5

CRISPR arrays

The CRISPR arrays of AP019371_5

>merge|AP019371|5|3791330-3791571|PILER-CR
GGGGCGGTGGGCGCACGCGGACGTGTGTTGTGTGCGCTGGTGGCCCGGGTCGGGGCGAGAGGGGTGGTGGGCGCACGCAGTGTTTGGTTTGCGTGAGCTGGGCGCCGTGCTGGGGGCGGTGGGCGCACGCGGACGTGTGTTGTGTGCGCTGGTGGCCCGGGTCGGGGCGAGAGGGGTGGTGGGCGCACGCAGTGTTCGGTTTGCGTGAGCTGGGCGCCGTCCTGGGGGCGGTGGGCGCACGC

>AP019371|5|1|3791330-3791571|PILER-CR
GGGGCGGTGGGCGCACGC	GGACGTGTGTTGTGTGCGCTGGTGGCCCGGGTCGGGGCGAGA
GGGGTGGTGGGCGCACGC	AGTGTTTGGTTTGCGTGAGCTGGGCGCCGTGCTG
GGGGCGGTGGGCGCACGC	GGACGTGTGTTGTGTGCGCTGGTGGCCCGGGTCGGGGCGAGA
GGGGTGGTGGGCGCACGC	AGTGTTCGGTTTGCGTGAGCTGGGCGCCGTCCTG
GGGGCGGTGGGCGCACGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH66819.1|3788463_3789423_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213234
AP019371.1|BBH66830.1|3798327_3798495_-|hypothetical-protein	unknown	unknown	gnl|CDD|238180
AP019371.1|BBH66814.1|3779806_3780805_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381300
AP019371.1|BBH66824.1|3792365_3793721_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
AP019371.1|BBH66815.1|3780814_3784858_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
AP019371.1|BBH66823.1|3791680_3792334_-|hypothetical-protein	unknown	unknown	gnl|CDD|378611
AP019371.1|BBH66828.1|3796844_3797822_+|adenosine-kinase	unknown	unknown	gnl|CDD|238917
AP019371.1|BBH66822.1|3790717_3791026_+|branched-chain-amino-acid-transporter	unknown	unknown	gnl|CDD|377512
AP019371.1|BBH66821.1|3790025_3790724_+|hypothetical-protein	unknown	unknown	gnl|CDD|224215
AP019371.1|BBH66829.1|3797834_3798335_+|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|379324
AP019371.1|BBH66827.1|3796362_3796731_+|hypothetical-protein	unknown	unknown	gnl|CDD|272875
AP019371.1|BBH66816.1|3785188_3785722_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH66818.1|3787672_3788467_+|transporter	unknown	unknown	gnl|CDD|226218
AP019371.1|BBH66831.1|3798533_3799673_-|aminotransferase	unknown	unknown	gnl|CDD|224029
AP019371.1|BBH66825.1|3793927_3795106_-|quinolinate-synthase-A	unknown	unknown	gnl|CDD|236489
AP019371.1|BBH66813.1|3779000_3779810_+|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100079
AP019371.1|BBH66832.1|3799839_3800775_+|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl|CDD|224537
AP019371.1|BBH66817.1|3786819_3787680_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226953
AP019371.1|BBH66820.1|3789406_3789961_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
AP019371.1|BBH66826.1|3795167_3796274_+|glycerate-kinase	unknown	unknown	gnl|CDD|376844

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH66819.1|3788463_3789423_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213234	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.	6.64642e-111
AP019371.1|BBH66830.1|3798327_3798495_-|hypothetical-protein	gnl|CDD|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	2.63365e-11
AP019371.1|BBH66814.1|3779806_3780805_-|aldo/keto-reductase	gnl|CDD|381300	cd19074, Aldo_ket_red_shaker-like, Shaker potassium channel beta subunit family and similar proteins. This family includes voltage-gated potassium channel subunits, beta-1 (KCAB1B), beta-2 (KCAB2B) and beta-3 (KCAB3B). KCAB1B and KCAB2B are cytoplasmic potassium channel subunits that modulate the characteristics of the channel-forming alpha-subunits. KCAB3B is an accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. The family also includes Drosophila melanogaster Hk protein, a founding member of aldo-keto reductase family 6 member B1 (AKR6B1), as well as voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa, founding members of AKR6C1and AKR6C2, respectively. Hk protein, also called hyperkinetic, is a beta subunit of Shaker (Sh) K+ channels and shows high sequence homology to aldoketoreductase. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	1.117e-167
AP019371.1|BBH66824.1|3792365_3793721_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
AP019371.1|BBH66815.1|3780814_3784858_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	9.362e-12
AP019371.1|BBH66823.1|3791680_3792334_-|hypothetical-protein	gnl|CDD|378611	pfam11241, DUF3043, Protein of unknown function (DUF3043). Some members in this family of proteins with unknown function are annotated as membrane proteins. This cannot be confirmed.	2.44018e-62
AP019371.1|BBH66828.1|3796844_3797822_+|adenosine-kinase	gnl|CDD|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	3.67209e-70
AP019371.1|BBH66822.1|3790717_3791026_+|branched-chain-amino-acid-transporter	gnl|CDD|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	8.07168e-07
AP019371.1|BBH66821.1|3790025_3790724_+|hypothetical-protein	gnl|CDD|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	3.19192e-40
AP019371.1|BBH66829.1|3797834_3798335_+|adenylyl-sulfate-kinase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	2.78818e-20
AP019371.1|BBH66827.1|3796362_3796731_+|hypothetical-protein	gnl|CDD|272875	TIGR00049, Uncharacterized_protein_in_nifU_5'region, Iron-sulfur cluster assembly accessory protein. Proteins in this subfamily appear to be associated with the process of FeS-cluster assembly. The HesB proteins are associated with the nif gene cluster and the Rhizobium gene IscN has been shown to be required for nitrogen fixation. Nitrogenase includes multiple FeS clusters and many genes for their assembly. The E. coli SufA protein is associated with SufS, a NifS homolog and SufD which are involved in the FeS cluster assembly of the FhnF protein. The Azotobacter protein IscA (homologs of which are also found in E.coli) is associated which IscS, another NifS homolog and IscU, a nifU homolog as well as other factors consistent with a role in FeS cluster chemistry. A homolog from Geobacter contains a selenocysteine in place of an otherwise invariant cysteine, further suggesting a role in redox chemistry. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	8.93313e-49
AP019371.1|BBH66832.1|3799839_3800775_+|cytochrome-c-oxidase-subunit-II	gnl|CDD|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	1.37074e-60
AP019371.1|BBH66818.1|3787672_3788467_+|transporter	gnl|CDD|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.48235e-39
AP019371.1|BBH66831.1|3798533_3799673_-|aminotransferase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	3.85046e-99
AP019371.1|BBH66825.1|3793927_3795106_-|quinolinate-synthase-A	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	4.55564e-156
AP019371.1|BBH66813.1|3779000_3779810_+|site-2-protease-family-protein	gnl|CDD|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	1.07723e-39
AP019371.1|BBH66817.1|3786819_3787680_+|ABC-transporter-permease	gnl|CDD|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	6.97674e-33
AP019371.1|BBH66820.1|3789406_3789961_-|XRE-family-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.09921e-14
AP019371.1|BBH66826.1|3795167_3796274_+|glycerate-kinase	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	2.85669e-143

Protein sequences

>AP019371.1|BBH66822.1|3790717_3791026_+|branched-chain-amino-acid-transporter
MLIATILILGAGTYAIRLSGVLLRERLELSDSLQRLLPMAAAALLAALAATAALMAGSEFAGPARPAGVLVGALLAWRKAPFVAVVLAAAASTALLRLAGVP
>AP019371.1|BBH66821.1|3790025_3790724_+|hypothetical-protein
MSSLKRTLRDVGALGAAMVAVGASFGAISIAYGLPPWAPILMSTVVFAGGSQFLAAGLIAAGNPIAAVLAGLLLNARHLPFGLAIADTIGGRWRDRLIGSHIMTDEATAFALASTDPVERRRVYWLVGTTLFVTWNIGTVLGVLLGGATGDPDALGLDAAFPAALIALILPSLRDRSTRLVALTGAVIAVALTPLLPAGLPVLCALLGLLVLFFPSRFRKAPEPAAAEESRC
>AP019371.1|BBH66820.1|3789406_3789961_-|XRE-family-transcriptional-regulator
MQQPAPPLVVIAAALRRERDRAGISLTELARRAGLAKSTLSQLEAGTGNPSIETLWALGVALDVPFSRLVEPPTSPVRVIRAGDGPRLRSDHAEFVATLLATGTPHTRRDIYLMELEPGEPREAEAHIPGSVEHIVVSQGRIRTGPVDEPVELGPGDYVTFPGDVPHRYEALEPAWAVLIMEHR
>AP019371.1|BBH66819.1|3788463_3789423_+|ABC-transporter-ATP-binding-protein
MIKMQDLHKTFSVRVKAGRFRRQKRTVSAVDGVSLTIDRGEMVGYIGPNGAGKSTTLKMLTGVLMPSSGTVEVCGLTPVPQRTRLALRIGVVFGQRSQLWWDLPLRESFALLRHVYRVPAADHAARLKQCRSLLDLDEFMDTPVRQLSLGQRMRGELTAALLHGPEVLFLDEPTIGLDVVSKQAVRQFLGSLGASGDVTLVLTTHDLADIERLCERLVVIDHGRVVHDGSIEALHARYGSRRSLVADLERPLPDGFTLPGAILTSTEAGGHRVTFALESSGAGAAVAGLVAAVGVRDLSVLEPDIEDVVARLYTASDVP
>AP019371.1|BBH66818.1|3787672_3788467_+|transporter
MANPYAALFTAQLRSVTTYRASFVVELVGNMGATVFDVITIVVLFGTAPRIGDFTLQEALLTVGLSSAGFALADMLIGNVDRLKVYVRTGTLDAVLVRPLPALPQLLLMDLPLRKALRVVFGFTVLGGAIAVNDIDWTPARVALVVITPLAAAAFFGSIFVISATLAFWWVDSGEVGAAFTYGGRDFTSYPITVYGPLFRGIFAYALGFAFVAYQPALALLGRTDPLGLPAWAGYLSPLVALAAAVIAAVVWRAGIRHYRSTGS
>AP019371.1|BBH66817.1|3786819_3787680_+|ABC-transporter-permease
MSRIDARVLTISRIGPFRSSATTFGVLVGSGFRRWSTYRQATIAGSFTNIVFGFLRCYVLLAVAAGVGGGQPGGYDAEQLATYVWVGQGLLAVIGIWGWTELAERIRTGDIAADLLRPVSPVTSYLAADLGRGLHGMLTRFAPPLVVGAIFFPLHVPARWQTIPLFLLSVILAVVICFACRYVVNATAYWLQDARGPIILWTLGSGVLGGLYFPLRLLPEWLTVTLWLGTPMPSLLQAPLDVIAERDPPAMQAGLVAIQVFWAITMLATARLVQRRAERKLVVQGG
>AP019371.1|BBH66816.1|3785188_3785722_+|hypothetical-protein
MLTGDVLDRGVRARVVLAWGVLARGVLAVRVLAGYVLTGRVLALTGCVLVRAVLTRTVVCRGRAVPGTVRCLARAVPGTVRCLGRAVSRNMRCLGGAVSGNVGCLGSGVPQTVGAGGVLRRARRNESWGGWAALVVRGAGARGVGLWGYWPSAPLSGRVGRGLLLGAAGWGTAGAAR
>AP019371.1|BBH66815.1|3780814_3784858_-|hypothetical-protein
MPPGAPGTYGRGPQDPNLRDPGYQARRSAPDQQSPWSGPEARPASGPVSPAAGAYGSARPAPPEAFPAWSEERRAPREGRTPEAPFDLRPVPQERNTPAPSRPAPQPTRMTPQQPSMPPAALYPHAPQPTPHSQPNPHAPQPNPHAEPNLHAPQPTSGARLTPAHPISAPAAPGVTPQHPVPDSAPRDLSSPHPIPGTANPGIAPVSGPVSGPDSDPVSGPVGPRIQPVSDLGAVPGQPVPDLRVPGQPASGPTEGFSGEVRQGDLSGTPGDHRQGVDQTQTIDPQRRSVRAEGFTEAPAERRPTSHARPDETGVHERLDEAAGRYEEPAAPSRARHASGVTAGYPTIGEPSPIAEPQAESTPAEEPHGLGWLLSQSGYGGTTPVIEPEPEEVLETEPDAEPRPQGWFAPAADEQPEEERPSEEQLSQEQPAAQEQAAAQTQAAAQEQPSEVQPDAEEPLSGVQLAEEAVTEESVEDEPVEDVPVEDEPVEDVPVEDEPVEDEPIMVEAMVDEPAVAVIDEPASIEAMVGEPGSVEATVDEPGSVEAGTDEFGSVEAGTDEPGSVEAMVDEPAAVVEVVIEEPIAIEAVGNEAIDDETGVDQLSEDEAIAVEAIADEPGSVVAEVDEPFAVEVVSEGPSEVEAVEGEAIGDEAILDQHSRDEASAVEAGGEDEAASVEPIVIERLLVEPISVEPSYDEPLVVEPIHDELVAEEAGGDEAVEDETAALDDEGAGFDKAFADFQAYADTAAVRAVEEPAFDKAFADFQAYADTAAGDGEPATEVIVEAESEPATELIIEADEATAVIAAPSEEATTVIAAPSEEATAVLEPPAEEPTAVIAAQAEEATTAIEAQPEEETETEPATVVIATALAAIVPDEESAPVEALTATAAEATAQTEKEQPGDVPESAPVRQRRDQPAPKDRRRADPEQILASYEWTFDPQTLREQVDDPDRLWDLVDRLTDRLEFAERDNVRAGLLSLRAVVSRVLGELDDALADAREALRHAESSAELRPISITKARLAQVLQWRGEFAEADRLYAQADSVELPSRTRAEILELAGRSAFEQGRHLEAVNHFERALDVRQGGDPELIERIELALDTISRKSGDGGWGPYPRTRDELLGLPASPMPLIDEGTNLWGYAAAVEPRYAEVTPFAEGVAWVRRPDTITWELVDITGKALIGGYVGITPFSDNLAWVKKDDSGWFLIDKHNQVVLQSAFEEARPFRAGMALIKQNGVWGAIDRTGRITVPPRWQSFATTLAIGGEVDGFSEDGLAVVESGGRLGVVDRDGGIVVEPAYAKIVIHPSALLVADDRGQWGALTRTGEPLVDLVHPDRAEAAAALDEEPRPVL
>AP019371.1|BBH66814.1|3779806_3780805_-|aldo/keto-reductase
MKHRHLGRSGLLVSEIAYGNWITHGSQVEEDAALACVRAALDEGITTFDTADVYAGTRAEEVLGRALKGERREGLEIFTKVYWRTGPGVNDSGLSRKHIMESIDGSLKRLGTEYVDLYQAHRYDKHTPLEETMEAFADVVHRGKAHYIGVSEWTAAEIRAAKPLADELKIRLVSNQPQYSMLWRVIEAEVVPASVELGLGQIVWSPLAQGVLTGKYKPGQQPPAGSRATDEKSGAGFIARWLEDDVLTRVQQLQPLADQAGLTLAQLGVAWVLQNPNVSAAIIGASRPEQVRDNVKASGVELDAGLLKAIDEIVDPVVTRDPSLTSSPANRP
>AP019371.1|BBH66813.1|3779000_3779810_+|site-2-protease-family-protein
MTYEPVYTRAPRNAFVPSPVFVGIVAVFAVSGFMTWSRFGNVKIDVFLFVISGWIISLCLHEYAHAVTGYFSGDLSVADRGYLRLNPLKYTHPLLSIVLPVIVVILGGIGLPGGAVWVDHRYIRSRLKDSLISAAGPLTNVVLALIVAVPFLAGLAPELSPSVVTAEHLEFWAALALLAFLQVTASLLNFLPIPGLDGGSIISPWFSPAYQRAWNLVAPWGFLLLFLLLWQTQLGSYFFEVVNWLAELIGVPYWLYQLGFELMRFWEAG
>AP019371.1|BBH66823.1|3791680_3792334_-|hypothetical-protein
MLYTAPFGYAADVSPLFRRKPEEAAPTEVEAVTTDADNRPKGYTPSKKELGVVTPKRAAVGRRVQDKAPENRKEAYKQLRERQRTERAEANEGMRNGDERYLLARDRGPERSLVRDIVDSRRTVGSWFIAGAVVVLIGSSVPNRTVQNFSTLVWALLALAVLVDSILIARKIKKLVKERFPQSTQRMGSLYLYGIMRGLTFRRMRIPKSKVEYGDKI
>AP019371.1|BBH66824.1|3792365_3793721_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MTDDVLIVHGGTPLQGQIRVRGAKNLVSKAMVAALLGESPSHLYDVPGIRDVEVVRGLLELHGVKVTDGAEDGELVMDPTNVESASTDEINVHAGSSRIPILFCGPLLHRLGHAFIPDLGGCHIGPRPIDFHIKSLREFGAIVDKTPEGMHLSAPNGLHGAKLELPYPSVGATEQVLLTAVRAEGVTELRNAAIEPEIIDLICILQKMGAIIKVHTDRVIEIHGVPRLYGYEHKPIPDRIEAASWAAAALATRGEIEVVGARQADMMTFLNVYRSIGGELKITDDRIARPGVTGAEGGIKFWHPGGELKAVALETDVHPGFMTDWQQPLVVALTQARGISIMHETVYEQRLGYTDALNQMGATIQVYRDCLGGTPCRFGRRNFMHSAVIAGPSKLHAADLRIPDLRAGFAHLIAALAAEGTSRVYGVDLIKRGYEDFEAKLAALGAHVERP
>AP019371.1|BBH66825.1|3793927_3795106_-|quinolinate-synthase-A
MMDVTSTWTEPQNTPLALLLLGKGTDPASERGVDCPGDLPAPSDPGLVARATAAKEALGSRVFVLGHHYQRDEVIQFADVTGDSFKLAQQAAARPDAEFIVFCGVHFMAESADILTKPDQKVILPDLAAGCSMADMAVLGQVETAWEHFEDLGITDQIVPVTYMNSSADIKGFVGRNSGVVCTSSNAKRALDWSFEQGSKVFFLPDQHLGRNTAVLEMGFDLDDCVLYDPHKPKGGLTDEQLRNARMILWRGHCSVHGRFTLDSVREVRERVPGVNVLVHPECRHEVVRAADHVGSTEYIIKALEAAPAGSAWAVGTELNLVRRLALAHPDKQIMFLDRAVCYCSTMNRIDLPHLVWTLEELVAGRVPNVITVDEKTAHEARVALDQMLALP
>AP019371.1|BBH66826.1|3795167_3796274_+|glycerate-kinase
MRVLICPDKFAGTLSAPAVADAVAEGWSVPDDVLVRRPLADGGPGFVEVLATALGGRRIPVSTVDPLGRPAPGEILVAGGTAYVESAQACGLHLLATSERDPKATISYGLGILLTAAVESGATEVVVGLGGSAVNDAGAGMLAALGAAPVDVAGNVLPYGGGPLITAAGLAGEPRLRQVSLVAATDVDNPLTGLHGASNVFGPQKGASREDVLRLDAALEHFAGVLEKAFGRTGLAAEPGGGAAGGLGAALIALGGRVTSGINLVTNLIGLDAELDAADLVITGEGSFDHQSLRGKVVAGIAAGARDRGLPCVVLAGRNETGHREAAAAGVTETHTLVEHFGSVEQALAEPARGLRELSAELAQQWSR
>AP019371.1|BBH66827.1|3796362_3796731_+|hypothetical-protein
MTTEAHTESTEATAPTGVTLTDVAAVKVKALIEQEGRDDLRLRIAVQPGGCSGLRYQLFFDERSLDGDVVNDFGGVEVVVDRMSAPYLAGATIDFADRIDAQGFTIDNPNAQNSCACGDSFH
>AP019371.1|BBH66828.1|3796844_3797822_+|adenosine-kinase
MKIAVTGSIATDHLMHFPGKFADQLIADQLHKVSLSFLVDDLVVRRGGVAPNIAFGMAKLGLRPILVGAVGADFADYRSWLERHGVDCDSVHVSDVAHTARFVCTTDDDLNQIASFYAGAMAEARNIELAPVNERAGGLDLVLIGANDPAAMIRHSEECRARGYAFVADPSQQLARMDGSDVLSLIRGAEFLMTNEYERSLLETKAGLTSEQVLDEVKIRVTTLGKDGVEITGRGIERIHVPVVPGVIGEDPTGVGDGFRAGFFAGVHWGLSLERSAQIGSLVAALVLETVGTQEYDIKPAEFTKRFAAAYGDDAAAEIAQFLNN
>AP019371.1|BBH66829.1|3797834_3798335_+|adenylyl-sulfate-kinase
MVLAVFAGLPGVGKSTLAAQVATELPAAVLAVDTVDFTLQRYDVQEHRPGYAAYGVVAALAEEQLKIGHSVIIDAVNPVKSARQLWVDLAERMDVPLRVVEVICGDDAEHRRRVEARYAARDHEGVPDWVRVLERQAEYEPYLGPRLVVDTYLAKDPVSPVVGYLR
>AP019371.1|BBH66830.1|3798327_3798495_-|hypothetical-protein
MIKLAKAIPGVAVGEIVRVLADDPAAANDIPAWCRMKGQEFVAGHGHQFDVRRIT
>AP019371.1|BBH66831.1|3798533_3799673_-|aminotransferase
MDYTGDPAGQPVYLDAASAAPLHPIAREAMLAALADGWADPARLYAAGRRAQQLLEAASAVVAEILSVRVDELSFWHSGTSAAQAAVLGGLKGRRRAGSTLVRSAIEHSSVILAAPDAVEVGVDRLGRLDLDAWQAAVSAPGVALASLISASHEVGTVQPVEEAAGLCSEAGVPLFVDAAQTVGRSPVPRGWDLLSASAHKWGGPPGVGVLVVRKGVRWISPHPQDDLYRPRPQGALDLPAVVAAAASLRAVSAEARAEGVRLTALVDHIRQTVAATVPDVEIVGDPVQRLPHLVTFSCLYVDGEALLHALDRHGFAVSSGSSCTSSTLRPSHVLEAMGVLSHGNVRVSLHRDTTSAEVERFLAVLPGLVAGIRKEAGF
>AP019371.1|BBH66832.1|3799839_3800775_+|cytochrome-c-oxidase-subunit-II
MGARSSATRPRAVGRAAGLGLGGATLLTLLSGCSLQDWGDAFGHFGWPSDGISLQAHEMYDLWIASVLAALAVGIGVWGLIFWCVIRYRKRGDELPVQTRFNMPMEILYTVTPVLIVAVLFYYTAIVQTSVDKLSKNPDQVVEIVAFKWNWQFNYRDGMGVEAKTVASTIGSSDVIPILVLPVGETIRFEETSKDVIHSFWVPEMLFKRDVFPGSVRNVFEVTLDKEGRYVGRCAELCGTYHAFMNFELVTVSPEKFDQFIESKKSGASTQQAMAAIGFTGAESYATTTSPFNTRRQTHSWNQSDSVAAGK

Crispr_ID: AP019371_6

• CRISPR_ID: AP019371_6
• CRISPR_location: 3846502-3846588
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_6

Consensus_repeat	Method
GGCTGTGACTCATTGCTGTCGAGC	CRISPRCasFinder

spacers of AP019371_6

>6.1|3846526|39|AP019371|CRISPRCasFinder
CGCCGTGGAAGCAGCCATGGGTCACAGCCCGGTGCGGTC

CRISPR arrays and Neighbor proteins around AP019371_6

CRISPR arrays

The CRISPR arrays of AP019371_6

>merge|AP019371|6|3846502-3846588|CRISPRCasFinder
GGCTGTGACTCATTGCTGTCGAGCCGCCGTGGAAGCAGCCATGGGTCACAGCCCGGTGCGGTCGGCTGTGACTCATGGCTGTCGAGC

>AP019371|6|5|3846502-3846588|CRISPRCasFinder
GGCTGTGACTCATTGCTGTCGAGC	CGCCGTGGAAGCAGCCATGGGTCACAGCCCGGTGCGGTC
GGCTGTGACTCATGGCTGTCGAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH66867.1|3834829_3835525_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
AP019371.1|BBH66873.1|3840694_3843001_-|hypothetical-protein	unknown	unknown	gnl|CDD|224851
AP019371.1|BBH66882.1|3852311_3853253_+|hypothetical-protein	unknown	unknown	gnl|CDD|197205
AP019371.1|BBH66877.1|3847486_3848515_+|pyrophosphate--fructose-6-phosphate-1-phosphotransferase	unknown	unknown	gnl|CDD|274155
AP019371.1|BBH66871.1|3837779_3838430_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
AP019371.1|BBH66872.1|3838627_3840016_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
AP019371.1|BBH66875.1|3844624_3846391_+|beta-glucosidase	unknown	unknown	gnl|CDD|224389
AP019371.1|BBH66881.1|3851358_3852300_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH66874.1|3843255_3844533_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
AP019371.1|BBH66885.1|3855131_3857003_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH66869.1|3836511_3837276_+|hypothetical-protein	unknown	unknown	gnl|CDD|225213
AP019371.1|BBH66883.1|3853249_3854230_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH66884.1|3854226_3855135_-|DNA-binding-protein	unknown	unknown	gnl|CDD|223531
AP019371.1|BBH66876.1|3846849_3847344_+|general-stress-protein	unknown	unknown	gnl|CDD|379804
AP019371.1|BBH66880.1|3850217_3851177_-|amino-acid-oxidase	unknown	unknown	gnl|CDD|334462
AP019371.1|BBH66879.1|3849496_3850255_+|hypothetical-protein	unknown	unknown	gnl|CDD|225910
AP019371.1|BBH66878.1|3848569_3849382_+|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl|CDD|237008
AP019371.1|BBH66870.1|3837301_3837793_+|3'-5'-exoribonuclease	unknown	unknown	gnl|CDD|374562
AP019371.1|BBH66866.1|3833875_3834688_-|hypothetical-protein	unknown	unknown	gnl|CDD|377113
AP019371.1|BBH66868.1|3835499_3836186_-|CRP-like-cAMP-activated-global-transcriptional-regulator	unknown	unknown	gnl|CDD|223736

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH66867.1|3834829_3835525_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	5.01733e-53
AP019371.1|BBH66873.1|3840694_3843001_-|hypothetical-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	6.61612e-45
AP019371.1|BBH66882.1|3852311_3853253_+|hypothetical-protein	gnl|CDD|197205	cd09106, PLDc_vPLD3_4_5_like_1, Putative catalytic domain, repeat 1, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins. Putative catalytic domain, repeat 1, of vertebrate phospholipases D, PLD3, PLD4, and PLD5 (EC 3.1.4.4), viral envelope proteins (vaccinia virus proteins K4 and p37), and similar proteins. Most family members contain two copies of the HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue), and have been classified into the phospholipase D (PLD) superfamily. Proteins in this subfamily are associated with Golgi membranes, altering their lipid content by the conversion of phospholipids into phosphatidic acid, which is thought to be involved in the regulation of lipid movement. ADP ribosylation factor (ARF), a small guanosine triphosphate binding protein, might be required activity. The vaccinia virus p37 protein, encoded by the F13L gene, is also associated with Golgi membranes and is required for the envelopment and spread of the extracellular enveloped virus (EEV). The vaccinia virus protein K4, encoded by the HindIII K4L gene, remains to be characterized. Sequence analysis indicates that the vaccinia virus proteins K4 and p37 might have evolved from one or more captured eukaryotic genes involved in cellular lipid metabolism. Up to date, no catalytic activity of PLD3 has been shown. Furthermore, due to the lack of functional important histidine and lysine residues in the HKD motif, mammalian PLD5 has been characterized as an inactive PLD. The poxvirus p37 proteins may also lack PLD enzymatic activity, since they contain only one partially conserved HKD motif (N-x-K-x(4)-D).	0.00882741
AP019371.1|BBH66877.1|3847486_3848515_+|pyrophosphate--fructose-6-phosphate-1-phosphotransferase	gnl|CDD|274155	TIGR02483, ATP-dependent_6-phosphofructokinase_1, phosphofructokinase. Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis].	0
AP019371.1|BBH66871.1|3837779_3838430_-|TetR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.42479e-13
AP019371.1|BBH66872.1|3838627_3840016_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.00209e-75
AP019371.1|BBH66875.1|3844624_3846391_+|beta-glucosidase	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	7.93114e-48
AP019371.1|BBH66874.1|3843255_3844533_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.55828e-25
AP019371.1|BBH66869.1|3836511_3837276_+|hypothetical-protein	gnl|CDD|225213	COG2334, COG2334, Putative homoserine kinase type II (protein kinase fold) [General function prediction only].	3.01406e-17
AP019371.1|BBH66884.1|3854226_3855135_-|DNA-binding-protein	gnl|CDD|223531	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility].	2.7647e-08
AP019371.1|BBH66876.1|3846849_3847344_+|general-stress-protein	gnl|CDD|379804	pfam16242, Pyrid_ox_like, Pyridoxamine 5'-phosphate oxidase like. This domain, approximately 140 residues in length, is mainly found in general stress proteins in various Xanthomonas species. It is composed of a six-stranded antiparallel beta-barrel flanked by five alpha-helices and can bind to FMN and FAD, suggesting that it may help the bacteria to react against the oxidative stress induced by the defense mechanisms of the plant.	4.03772e-72
AP019371.1|BBH66880.1|3850217_3851177_-|amino-acid-oxidase	gnl|CDD|334462	pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.	7.15259e-24
AP019371.1|BBH66879.1|3849496_3850255_+|hypothetical-protein	gnl|CDD|225910	COG3375, COG3375, Uncharacterized conserved protein [Function unknown].	9.34399e-41
AP019371.1|BBH66878.1|3848569_3849382_+|pyrroline-5-carboxylate-reductase	gnl|CDD|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.34461e-98
AP019371.1|BBH66870.1|3837301_3837793_+|3'-5'-exoribonuclease	gnl|CDD|374562	pfam16473, DUF5051, 3' exoribonuclease, RNase T-like. This is a highly divergent 3' exoribonuclease family. The proteins constitute a typical RNase fold, where the active site residues form a magnesium catalytic centre. The protein of the solved structure readily cleaves 3' overhangs in a time-dependent manner. It is similar to DEDD-type RNases and is an unusual ATP-binding protein that binds ATP and dATP. It forms a dimer in solution and both protomers in the asymmetric unit bind a magnesium ion through Asp-6 in UniProtKB:P9WJ73.	1.36671e-12
AP019371.1|BBH66866.1|3833875_3834688_-|hypothetical-protein	gnl|CDD|377113	pfam03729, DUF308, Short repeat of unknown function (DUF308). Family of short repeats that occurs in a limited number of membrane proteins. It may divide further in short repeats of around 7-10 residues of the pattern G-#-X(2)-#(2)-X (#=hydrophobic).	0.00133167
AP019371.1|BBH66868.1|3835499_3836186_-|CRP-like-cAMP-activated-global-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.71683e-39

Protein sequences

>AP019371.1|BBH66875.1|3844624_3846391_+|beta-glucosidase
MFAYQNPELPIEVRVSDLLSRLTLAEKAGLMFHTMIAVNPDGTLAEGNEMISSASELITGKLINHVNILTMGPVTPRRIAEWHNRVQELAAKAGHGIPVTVSTDPRHGVIDNPAASAAAGGFSAWPEPIGLGATKDPDLVREFADIARQEYLAAGIRVALHPMADLATEPRWARTSGTLGSDADMVSALLAAYVRGLQGDSLGTSSVAAMVKHFPGAGPQKDGEDAHFAYGREQVYPGGMWDYHLKPFEAAFRAGAAQVMPYYGMPVDTTHEEVGFGFNKGVIEGLLRQRYGFDGVVCTDWGLVTDAVIFGEPMPARAWGVEDLDRHDRVLRILEAGADQLGGEQCPELIVDLVSQGRISEERIDVSVRRILRDKFRLGLFDDRRYVDPDAAGRIAGQPSFRAAGVSAQRRSVVVLTDRPAAAGSAPVLPLTEGITVYLDGVDPAVAASYAKVVDDPALADVAIVRRSAPFEPRGGGFEAFFHAGRLDYTESELAPIVSLAETLPTVVDVMLDRPAVLTPLAATAGALTGTFGAGDEALLDVLFGRVPSAGTLPFELPSSMAAVEASREDVPNDTEAPLFPYGHGLKI
>AP019371.1|BBH66874.1|3843255_3844533_+|MFS-transporter
MTTLQSRPASETADKTQQPDAPTRLIVAMALAQLGAYLTILTPVVVTMSIRVAQIAPDDKAAALGTVLSVGAILALIGNPFFGAMSDRTTSRFGRRRPWLIGGMVVGFAGLLVVATGGGVPALTAGWALAQLGVNATLSTLTALLADQIPSQQRGKVSGILGLMTSVAILVGSALAAALAGSAVLMFLVPAAIGVATVALLVVVLKDRPAEKGHFSSYGMKEFFRTFYINPRRHPDFAWNIVSRFLIWMGLASVTTYQSYLLIDRFGYTTDDVATGILIATLITTVGLVAGSTFGGVLSDRTGMRKPFVLGAGIVIAAALVIIALANSFPVFLVACAIFGVGEGVYLAVDLALATDVLPNPDDAAKDMGVLNIANALPQSLVPILAAPILAIGSSDDSNYGLLFLLGAVVAVVGSVLVRMVRGAR
>AP019371.1|BBH66873.1|3840694_3843001_-|hypothetical-protein
MRRDLIFAAVREAGRISRADLVRRTGMARMTVNSLVADLLAAGVLAEEAAAPTGERAGRPARSLTLGPAAGGVVGAVISADGVRVAEADLTGSILDERHHHIDTSDPVTALDAIASVITGTGRVWSTVAGLSAPISGGIVQSSSVLPGWAGIAPAAELSRRVGHRVIVRNDADLCLLGEVGYGVAAGHQDVCYLRVATGIGCGLLLGGVVHHGATGVAGEIGHVQVDETGALCHCGNRGCLETIASPRQILAALETGYGAPITAEQAVELARTDATAERIMADAGRMIGRVVAALANGINPSLVVLDGPLISSDGPIVSGVVESLHRYAQPEVVESTAVRVSALGGRAALLGAVGAALRATPAARGERAFASASSPAPSSVAAPGRRERLVRREMIVEALRGRGSTARSDLVKITRLPRAAVVDILAELRHDGVVELCAPAEPRAGRPSPHFRLTAGGGRLIGLALAGPGIRAVVADGTGHVEESLTVPFPMSNDSHPILRATAEMARELFERHGPEARIAVSVPSPVHPETGRFGARSVLPMFSGFAPAEEIATAVGRPVLVENNAQLAALAEMRRGAARGSRDVLYLKADQHTGAGIVAGGRMHRGAIGYAGEVGHLNVRDIGPLCICGSRGCLSAFLTPAYFGALLENRPSAGGGSPGSQLAAGIFRTGEDRLLSLASGGDRPARRALLDAGRLIGRIVAPLCDVLNPGVVVVGGRFVEAGAFVVDGVREALMRHCAPSAAAGLKVVPAELGSDAEVLGAIEMLL
>AP019371.1|BBH66872.1|3838627_3840016_+|MFS-transporter
MVVLDATIVNIALPTAQADLGFDDAGRQWVVTGYALAFGSLLLLGGRLSDFFGRKRMFVIGLIGFALASALGGAAQNLELLIFARALQGAFGAALAPAALSLLSITFTEPAERGKAFGIFGAISGAGGGMGLLLGGVLTEYVSWRWCLYVNLVIAAIAVAGAFLKLKDEPVAANGKIDIPGTIAAVAGLVSLVYGLANAETDGWTDAMTLGPIVAGLVILVIFVLIERRVEHPLLPMRVVLDRNRGGSYASIAIAGAGMFGIFLFLTYYLTAVLGFTPVKTGLAFLPMLGSVMLTATTAGSILTPKIGPRPLVPLGALVAAGGMLFLTQLQLDSTYASGVLPGLIIIGLGLGLVFAPTQNAATSGVEHHDAGVASAMINTVQQIGGSIGTALLSSFAASAASDYMVGKEPTPLVQAQAALESYHTVFWWSTGFFVLAAIVAAVLFRTGPLDVDPDAPKAMAH
>AP019371.1|BBH66871.1|3837779_3838430_-|TetR-family-transcriptional-regulator
MTIEARPLRRDAQRNRERIIEAAHEVFATRGFAATLDDVAHHAGVGVGTVYRRFPTKESLVEAVFTDRLEDMVTLAEEALTADSAWDGLVDFFRRAARMHAADRGLRDAALSIDADHFGQVGEHMLPLLQQIIDRAHAEGTLRPDAGMHDFPIILAMVTELAQNSTACRPEIYERYLSLLLDGLRACPGHGDLGPQLTEADVQAVMKECVPPLKSR
>AP019371.1|BBH66870.1|3837301_3837793_+|3'-5'-exoribonuclease
MPYRYFYDCEFIEDGRIVDLVSIGVVDEFGREFYAISTEFDDSKAVPWVRRNVLDKLPSPADKAWRSRERIRDDLYEFLMEPLRGRSEQMELWAWYAAYDHVALAQLWGAMPALPREIPRFTKDLRQRWDDQGRPKLPEMAGRHDALVDARHNLARWEVLSGS
>AP019371.1|BBH66869.1|3836511_3837276_+|hypothetical-protein
MSRGWDVTAATGRYVARLAESGARQPMEAGLVAAEHLRLRRIDAGEPIRTLAGALTVDTADGALAVQRRLPGRHLDGRDPVDQQWWGERLGVVHKALQGFRHAGLRPWQLPDPDAPHLDTEPWLRGTVTAAVAAATRLTVTDRLTYGTLHGDPGADVFVLDPATGRSGVLHYGACGTGPLVYDVAAAVADAGGPEHAGELLDGYLAAGPVRHDELDAALPVLLRLRWAVQAERAARRGCARALAIARAALESES
>AP019371.1|BBH66868.1|3835499_3836186_-|CRP-like-cAMP-activated-global-transcriptional-regulator
MDHRLPDSGDALTGVEMFAGLEPDVRQRVIATAVPRHYRKGQILFVEHDPGDSLIIMKRGAVAVFRTAPTGERAVLTVVRPPDVLGEVSLLDASTRSASAEAIEDSQALSLSRAAFMDLVHSNPRILDAVMRSVGGLIRRLTEQNADHVFLDLPGRVAKTLVRLSGESQAPMITIELNQSQLAEMAGGSRQSVNQAIGSFANRGWLRTEGRRIVVTDVQALKRRAGMN
>AP019371.1|BBH66867.1|3834829_3835525_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MFYWLLKLVVLGPVLRLLFRPKVEGLANVPRSGPVILACNHLSFSDSIFTPLIMRRKVTFVAKAEYFTGKGIKGWLSRMFFVGAGTIPVDRSGGEAAQAALDTLLRVLKEGNVAGIYPEGTRSPDGRLYRGKTGVARLALESGAVVVPVALLNTDEIQPTGTLVPAVKRVRIRVGEPLDFSRYAQSRGDRFVERAITDEIMYELMVLSGREYVDVYAASLKNPVSSSPLAA
>AP019371.1|BBH66866.1|3833875_3834688_-|hypothetical-protein
MTTGGARRGRRDNGLDAADYAVAGDVDPRVGEHLLDVLAAGGIAAYLQPTADLNPILRATTLPARPIDRLYVDRTRLETAREHLQKVTGGALPTPPSPPTPTDTRPQAEVDAEWAKIIAGFHTLDDSAGTPWPEAESVGPVDPPRPLGEDGRPLNRRRTDPQPPPKDEDQSLLYGLDTFGADLPESDDDEDDRYIPPPPPPMPKISKYAVFGLLGVVVGFVLFLFPRLLPLDSTYVTLFGFAAIVGGAVTLVWRLRSGDDDDEFDDGAVV
>AP019371.1|BBH66876.1|3846849_3847344_+|general-stress-protein
MSDEQAQREKVREIVAEARICMVTTMTEDGRHVSRPMALQDVEFDGDLWFFTYSDSDLVEQIGRHPQVNVAFSDTKQNNWVSIAGAASRVDDRAKAEELWSPVLKAWFPDGLETPNLTLVKVDGETAEYWAAAHSSKVVTMLGYAKAAVTGKTPDAGENETVRL
>AP019371.1|BBH66877.1|3847486_3848515_+|pyrophosphate--fructose-6-phosphate-1-phosphotransferase
MRIGVLTGGGDCPGLNAVIRAVVRKGVTAYGHEFVGFRDGWKGPLEGLTKPLGIAEVRGILPRGGTILGSSRTNPFKIEGGVERIKANLAEQGVDALVAIGGEDTLGVATKLHDLGVNVVGVPKTIDNDLNGTDYTFGFDTAVNIAMEAIDRLHTTAESHHRTLVVEVMGRHAGWIALHAGLAGGANVILLPERKFDVEQVATYVTKRFQVEYAPIVVVAEGAQPLDGQMVLHNQELDSFGHVRLGGIGQWLAEQIEEKTGKEARTVVLGHIQRGGTPTAFDRVLSTRFGLQAIDAVNDGDFGKMVALRGTDIVRIPLIEGTGELKTVPLERYEEAEVFFGN
>AP019371.1|BBH66878.1|3848569_3849382_+|pyrroline-5-carboxylate-reductase
MANHTVAVIGAGKIGELVISGLLRSGWPADRLLITTRRPARAGDLSDKYGVTAVDNATAVVEADILAIAVKPQDAGALFDEIGAQIPAGKLVVSLCAGLTTEFFAARLPEGTPVVRVMTNTPALVDQAMTAISAGPHATDEHLDVAEEMFKPLGATIRVPESQQDAVTALSGSGPAYFYLLVEAMIDAGILLGLPRQTAHELIVQTAIGSAVMLRDSGEHPVKLREAVTSPAGTTIAAVRELENHGVRAALLAALEAARDRARQIAGEMK
>AP019371.1|BBH66879.1|3849496_3850255_+|hypothetical-protein
MTQQEVTFRHLRSIEELEEMVNLLCEVWETDSPIDLTNVSTLRAEVAAENYVVGIFGSDSRMIAAGYAIRGKGHIHSHIVGVHPKHQGHGYGYELKQHEAKWARDEDYPCIRWTYDPLVRRNAYFNLAKLTCTVQSYEKNFYGEVKDGLNDNDVTDRLMVEWRFGDGEPIEVDAPEEADSWDFRRRPTALLRLSGDLALVPTPADIATLRRDDAARAREWRFGVRDGFIEAFDEGFTVSGFSPDGWYVLRRR
>AP019371.1|BBH66880.1|3850217_3851177_-|amino-acid-oxidase
MTHGTDVVVVGAGVSGLTCAVRLAEAGLRVLVRSADSPLTTTSCAAGAIWGPHLVAHDRAESWALASLGVFRELAADPVATGVRMTWGVEAGQDVPRPGPGAEGVRLCAAVELPPGYTSGWEYRVPLIDMTRYLDYLTYRLLNKNGEIQISRVDDLPALGPLVVNCTGLGARELVPGDPIRPVRGDLLVLDNPGIDTFFVEHDEDDGDGLTTYVLPQGDRVMLGGSRFAGEWSDEDPQIRQDILDRCARAEPLLAGSRVREHRVGLRPVRDRVRIGPDDRYPHVIHNYGHGGGGVTLSWGCADEVLALTGAGAHTTRRG
>AP019371.1|BBH66881.1|3851358_3852300_+|hypothetical-protein
MLPSSTALPADAGQRLLALTSGAQVLRSDRPMSYVVSPDRLTGVDCQVPTGPHGSARAIGTVTTRAVLTGGHVLQTSARTAATRSPHGRRLPWSYYLARPSTVEVVGKYRERALADAFLDSRPAPPMLNLAAIAGHTADRVRASSLVDSRVPFRSRQTTVRWVATLGAEEDALTFTVEGADHRTVRIQSRGEEPAAIVALCEDLAMHDWLLTTLTGLVTRAALTGPKPSVAADRLRPAVDHLLHLWMPGARLEVQTRRFWEQMEQRAGFGRQWAASVQRIRDHLALSTLRELGTLRDLGMLRDLGSLAGPAAS
>AP019371.1|BBH66882.1|3852311_3853253_+|hypothetical-protein
MPAGSSGRRLSEVVRKVVIALVTGGVAFALTNLAEKDPILSVTLSVLVGGSALVVQFLVEFENRLREVQIGQVDQALQIRACVDERFRAISDATELFGAIEESAVQTELLSQLVRHSTKIGTESPGLAHRLAQRELERMSEFLKELGDGAEAIYDGEDRDWLLSLAHSTEHGIDATSLTTVDGGGMWATDLGQRYLDAQRDAVQRGVKIRRIFIQDRPEPGGQTALDKIYRQHADIGVEVRVLDLSNATDLRRTSLFDFVLFDGVISYEVTTGSWIDENTPPIVVNTRLVLRSSRVEERSERFRELWDVAQPR
>AP019371.1|BBH66883.1|3853249_3854230_-|hypothetical-protein
MTDPAATFQERSAQPRVEQVPLAHLSIELGHLYMEDYAGGIDQLRRHFAEVRPWVAAAQERLAGMLPAGRPPRISTCFLVDDYFTKFSTPAEVIGQLETAAADNGLTIDYLAREAGCARAGDVRPAELVLDRLVADPPQGTDGVWPPPEESGWLTNGDRPPGSSAQPAMTRRLAWQPPTENAKNRHSIFLAVEIFSEEPDGRLWSCPYLAAVWQLLRLGMLRCDGRPVAPPQPRGDRWPEDWDAMPAVVRLNPKAQPFSAYRTLSMLARRFQNIEAAVGVVIGQVDVDEEVRQQVRKRAEGEGFALPRDLVQRISYVFDGDSTKLL
>AP019371.1|BBH66884.1|3854226_3855135_-|DNA-binding-protein
MTMLVFATSDKGGTGRSVTTSNVAYQSALAGNDVCYLDFDFGSPTAGSVFDVDAGQVGVREGGLHSYLLGKVSAPGQIDIFAQTERDSVRERPYDAGRLILLPGDSGVGEFPSSPELVRRCANLIGRLIGEFDICFVDLSAGRSYALQMALAVAQQMTGVTTRWLVYHRWTKQHVIAAAALVHGEHGILDTGADLGHDREDLLASLRFVRTALIDPARPGLTSQQAVWITEWDRKLQAIAQAEGVGPLWLLDSVPLDPVLQWREQLITAHDVNNIGIANERTAEAFKRLADLLFDDKAWEVR
>AP019371.1|BBH66885.1|3855131_3857003_-|hypothetical-protein
MRVQPRQQLLEIWQAVVEHSYRDGEWVWGGRDGRNSISDAEQLLCILGPATGIEQFALDSPERVAEDVKAVMKPFGGVMDIPHTLLEAVEAYLTTYTDKNGTPIFAAESYFRGTGVATGDGVEPEPQQLAQPVVDSFAISLSLSLAAIGFARQFRKSLKRPSARAEIDRLEAMASKRLSAAMVGLLRSFTVNIFPVDSRDGRALCRTVNQRGLSIPRIVPQLQDSLREIRAALRDVTMGSGAGVADELDHPDRLFECGWSWGVVRDAPAIITSQDVGDQLPGMAEPAPYIYFTTVALDAIEALFSARTRQLGLLNEEQLRLAQGLQLRWDLTQSYWSKIAVPAGSGGSGTRWPLEDIPWQRTTEKESEYFSLHVSSIVVQDLVRKRAGDADLDRVGKVLEELANRSRINRRVFAGDKSYLLHAPGFPINLSGSDDLGGPQLIWMMSDFAPLLLKRTISLAGLLGDPQLRGRMLALADEIWAHLDARRLEDDRRRGLWDQPGLVFEEFDGSYAAPSWYHTKRVVDCLITASQVISEPPLRSDQLAELAGDLLSEADHIYDQELLQGSPNSGHAMQTDLQALAAKLKRGRSILDEKPGTAYALAVDVLLSLDRFAAARSDLEGES

Crispr_ID: AP019371_7

• CRISPR_ID: AP019371_7
• CRISPR_location: 3926326-3926568
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of AP019371_7

Consensus_repeat	Method
GGCGTGGCGGGGCGNGNCGNGGC	CRT

spacers of AP019371_7

>7.1|3926349|32|AP019371|CRT
GGGGCGGGGCGGGGCGTGGCGGGGCGTGGCGG
>7.2|3926404|32|AP019371|CRT
AAGACGTGGCGTGGCGTGGCGCGGCGAGACGT
>7.3|3926459|42|AP019371|CRT
GTGGCGCGGCGGGGCGCGGCGGGGCGAGACGTGGCAAGACGT
>7.4|3926524|22|AP019371|CRT
GTGGCGTGGCGCGGCGGGGCGA

CRISPR arrays and Neighbor proteins around AP019371_7

CRISPR arrays

The CRISPR arrays of AP019371_7

>merge|AP019371|7|3926326-3926568|CRT
GGCGGGGCGGGGCGGGGCGGGGCGGGGCGGGGCGGGGCGTGGCGGGGCGTGGCGGGGCGTGGCGGGGCGAGACGTGGCAAGACGTGGCGTGGCGTGGCGCGGCGAGACGTGGCGTGGCGGGGCGAGACGTGGCGTGGCGCGGCGGGGCGCGGCGGGGCGAGACGTGGCAAGACGTGGCGTGGCGGGGCGAGACGTGGCGTGGCGTGGCGCGGCGGGGCGAGACGTGGCGGGGCGTGGCGCGGC

>AP019371|7|1|3926326-3926568|CRT
GGCGGGGCGGGGCGGGGCGGGGC	GGGGCGGGGCGGGGCGTGGCGGGGCGTGGCGG
GGCGTGGCGGGGCGAGACGTGGC	AAGACGTGGCGTGGCGTGGCGCGGCGAGACGT
GGCGTGGCGGGGCGAGACGTGGC	GTGGCGCGGCGGGGCGCGGCGGGGCGAGACGTGGCAAGACGT
GGCGTGGCGGGGCGAGACGTGGC	GTGGCGTGGCGCGGCGGGGCGA
GACGTGGCGGGGCGTGGCGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH66953.1|3933948_3934821_+|hypothetical-protein	unknown	unknown	gnl|CDD|377370
AP019371.1|BBH66940.1|3917088_3917520_+|transcriptional-regulator-MraZ	unknown	unknown	gnl|CDD|234728
AP019371.1|BBH66948.1|3928443_3929544_+|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase	unknown	unknown	gnl|CDD|234825
AP019371.1|BBH66952.1|3933178_3933889_+|YggS-family-pyridoxal-phosphate-enzyme	unknown	unknown	gnl|CDD|223402
AP019371.1|BBH66949.1|3929566_3931003_+|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl|CDD|234757
AP019371.1|BBH66944.1|3921879_3923427_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl|CDD|234660
AP019371.1|BBH66951.1|3932051_3933170_+|hypothetical-protein	unknown	unknown	gnl|CDD|236468
AP019371.1|BBH66946.1|3924799_3925915_+|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl|CDD|234638
AP019371.1|BBH66937.1|3913192_3913906_-|glutamine-amidotransferase	unknown	unknown	gnl|CDD|225974
AP019371.1|BBH66950.1|3931007_3931775_+|cell-division-protein-FtsQ	unknown	unknown	gnl|CDD|135428
AP019371.1|BBH66955.1|3935193_3936006_+|cell-wall-synthesis-protein-Wag31	unknown	unknown	gnl|CDD|377456
AP019371.1|BBH66954.1|3934844_3935150_+|YggT-family-protein	unknown	unknown	gnl|CDD|376765
AP019371.1|BBH66938.1|3913895_3915116_-|ligase	unknown	unknown	gnl|CDD|223840
AP019371.1|BBH66941.1|3917753_3918824_+|ribosomal-RNA-small-subunit-methyltransferase-H	unknown	unknown	gnl|CDD|234597
AP019371.1|BBH66939.1|3915669_3916491_+|hypothetical-protein	unknown	unknown	gnl|CDD|237555
AP019371.1|BBH66956.1|3936048_3936954_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH66942.1|3918889_3919549_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH66947.1|3927058_3928444_+|hypothetical-protein	unknown	unknown	gnl|CDD|274232
AP019371.1|BBH66945.1|3923423_3924803_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl|CDD|223841
AP019371.1|BBH66943.1|3919554_3921849_+|penicillin-binding-protein-PbpB	unknown	unknown	gnl|CDD|223839

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH66953.1|3933948_3934821_+|hypothetical-protein	gnl|CDD|377370	pfam04472, SepF, Cell division protein SepF. SepF accumulates at the cell division site in an FtsZ-dependent manner and is required for proper septum formation. Mutants are viable but the formation of the septum is much slower and occurs with a very abnormal morphology. This family also includes archaeal related proteins of unknown function.	6.39178e-29
AP019371.1|BBH66940.1|3917088_3917520_+|transcriptional-regulator-MraZ	gnl|CDD|234728	PRK00326, PRK00326, transcriptional regulator MraZ.	2.69958e-66
AP019371.1|BBH66948.1|3928443_3929544_+|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase	gnl|CDD|234825	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional.	8.52953e-123
AP019371.1|BBH66952.1|3933178_3933889_+|YggS-family-pyridoxal-phosphate-enzyme	gnl|CDD|223402	COG0325, COG0325, Predicted enzyme with a TIM-barrel fold [General function prediction only].	3.88785e-82
AP019371.1|BBH66949.1|3929566_3931003_+|UDP-N-acetylmuramate--L-alanine-ligase	gnl|CDD|234757	PRK00421, murC, UDP-N-acetylmuramate--L-alanine ligase; Provisional.	1.73703e-176
AP019371.1|BBH66944.1|3921879_3923427_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl|CDD|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
AP019371.1|BBH66951.1|3932051_3933170_+|hypothetical-protein	gnl|CDD|236468	PRK09330, PRK09330, cell division protein FtsZ; Validated.	0
AP019371.1|BBH66946.1|3924799_3925915_+|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl|CDD|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	3.72543e-149
AP019371.1|BBH66937.1|3913192_3913906_-|glutamine-amidotransferase	gnl|CDD|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	5.75975e-68
AP019371.1|BBH66950.1|3931007_3931775_+|cell-division-protein-FtsQ	gnl|CDD|135428	PRK05529, PRK05529, cell division protein FtsQ; Provisional.	1.97644e-29
AP019371.1|BBH66955.1|3935193_3936006_+|cell-wall-synthesis-protein-Wag31	gnl|CDD|377456	pfam05103, DivIVA, DivIVA protein. The Bacillus subtilis divIVA1 mutation causes misplacement of the septum during cell division, resulting in the formation of small, circular, anucleate mini-cells. Inactivation of divIVA produces a mini-cell phenotype, whereas overproduction of DivIVA results in a filamentation phenotype. These proteins appear to contain coiled-coils.	6.13838e-15
AP019371.1|BBH66954.1|3934844_3935150_+|YggT-family-protein	gnl|CDD|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	0.000214416
AP019371.1|BBH66938.1|3913895_3915116_-|ligase	gnl|CDD|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.23547e-40
AP019371.1|BBH66941.1|3917753_3918824_+|ribosomal-RNA-small-subunit-methyltransferase-H	gnl|CDD|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	6.72333e-145
AP019371.1|BBH66939.1|3915669_3916491_+|hypothetical-protein	gnl|CDD|237555	PRK13914, PRK13914, invasion associated endopeptidase.	4.82024e-19
AP019371.1|BBH66947.1|3927058_3928444_+|hypothetical-protein	gnl|CDD|274232	TIGR02614, Putative_lipid_II_flippase_FtsW, cell division protein FtsW. This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	9.23127e-107
AP019371.1|BBH66945.1|3923423_3924803_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl|CDD|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	5.6459e-139
AP019371.1|BBH66943.1|3919554_3921849_+|penicillin-binding-protein-PbpB	gnl|CDD|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	8.55153e-130

Protein sequences

>AP019371.1|BBH66946.1|3924799_3925915_+|phospho-N-acetylmuramoyl-pentapeptide--transferase
MRAVIVAAAVAFLISLFGTPVAIKVFSALKAGQPIRTIGPQTHLGKRGTPTMGGVAFILATVFAYVAGHLALTTLPDRQIAQEKPTMTALVLLGLFVFCGAVGFLDDFLKVRKKNSDGLSAKGKLLGQLLIGTAFGLVALNFKSTNGQTVASEHISFIRDVSWLDVGKVGSVMVFVFVIMAMSNGVNLTDGLDGLATGASILVLGAYSLIGFWQYRHWCGDDDYRLTSELTQQHCYQVRDPLEIAMIAAAAAAACVGFLWWNTNPARIFMGDTGALALGGLIGGLAVATRTTLLSVIIGGLFVIITMSVVIQIISFKTTGKRVFRMSPLQHHFELAGWSEVNIVVRFWIIAGICAAIGLGLFYSDHLAVMG
>AP019371.1|BBH66945.1|3923423_3924803_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MIPMTLAEIAAVTGGEVVNAAGDVTVTGGVEYDSRKVGPGGLFVAFAGEKADGHDFAAGVVAAGAAGVLATRDVGVPSVLVSDQLAALAALARHVTKNLDKLTVVGLTGSSGKTTTKDYIGQLLSRLGPTVAPAGSLNNELGFPYTVLQASAETRFLVLEMGARGIGHIRYLTEIARPKIGVVLNVGAAHIGEFGSVEGTAQAKGELVESLPADGVAILNADDPLVAGMASRTVAPVVLTGEASSAAVSASDVVLDDAGRASYVLRSAEKSGHVRLAVAGRHQVANTLAAAAVALHAGMDFDAVVAALGSVGVVSGRRMDVFDRQDGVRVVDDSYNANPSSMSAALRALASMGSGRRTTAVLGYMAELGEYEISGHSEVGELAASLGIDRLIVVGANARPILDGAAAVADRFFAADQAEAIAILEKDLRADDVVLVKGSRYRTWDVADWLRRSEEVQPK
>AP019371.1|BBH66944.1|3921879_3923427_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MRHGVGSDAVSGIPRPTDVTPYPLRQLAELLSAETADGDTDVTGVTHSSGAVRPGDLYAALPGANRHGAEFITAAASAGAVAVLTDPAGAARAAEAGLPALVVDDPRAVLGAVASAIYGDPSRRLTMIGITGTAGKTSTSYLVEAGLRAAGLVTGLVGTVETRLGDFVVKSVRTTPEATDLQAILAAGVERGVSAVVMEVSSHALVMGRADGISFAAAGYTNFGQDHLDFHPTAEEYFSAKARLFDGRSAVEVLNYDDDAVMRLKRGASVTYSASGNVAASWWASDVRPSDYGQIFTAHGPGGITVETGVALPGLHNVANALLALALLVGAGVDPATAGRGILECKGVPGRLEQVEAPGEVLGVVDYAHKPNAIVAALAALRELATGRGGHLICVIGAGGDRDKGKRPLMGDAAAHGSDLVIVTDDNPRTEDPAVIRAAVRQGAEEATAPAKVIEVAGRRAAIAEAVRLASAGDVIAVLGKGNEQGQEVGGEVLPFDDRIELAEALLAAATGGRE
>AP019371.1|BBH66943.1|3919554_3921849_+|penicillin-binding-protein-PbpB
MSPRDDETPRRGTQPRRGSSRDLPAEEPEETPGRRNRSSIGDARAYTPRGRTVAERGRLPRSGRTTDPFRPALQVLDGGETPPRVRGRGRDQVEKDEPATTAARRPEKERDKAVPRTKESPAKEGRARAGGASPRTGKDRAEREREAGRGAGPRRRPPARSGRGRPDDRRSTEKRVPAEPPKLANSTRRLRLGTVLALSLFVTIGVRLVVLQVATSPDEAESLLALRERRLSTVELPAPRGSILDSSGAVLAHSVEARYVYADPENAGLQKNIAGTAAKLAPLLRVPASELAVGMERKQSLGRWLKFRYLARGVDVGIADKIDDMELPGIYTHTDERRDVPGKDLAANLIGFTGDDHHGLEGLEARYDELLHGTDGKRVFEVGKGSLNVQITGGYEQYTAAKPGNSLQLTIDRDVQYEVQRILDAEAEKKKATVAGAVVLDARTGEVLAQASYPAYNAAKPEDSDAEDRADVPSSVVTDPGSSHKAFIFGAALQEGVITPDSTMKIGPGLERGGYPFRDTHPQDPGTEMTMPGLLAYSSNVGTILIAEKLGKEKVYEYQKLFGLGQATGEGVLGEADGQLLEPSQWSGSAYGSVPIGHSVSATLIQMAAAYGAIANDGTYIQPQLIKATISGADGTVTPAAAPKTHKVLDPQVASQLRTMMEAVVDVKGGTGGAAAVPGYRVAGKTGTGKMLTDGQYTSHNASSFIGMAPAENPRYVIAVSMDVATGGGGDVAAPAFSEMMSYALLHYRVPPSGTKPPTFKIHP
>AP019371.1|BBH66942.1|3918889_3919549_+|hypothetical-protein
MDMSERSDAPRSGGRSAPRETTGAGARGVRQNSGRSDTRRSGMRSRGEESPAARGTRLGGADGTAALALEVTDLSVTAADPAPAGRPRLWVAPPLPMRAPRATFAASVAAVVLLGVLGILLVNTKTMEQSFKLDALQKEQAVLDKKQQGLEQQLIQASNPGNIHAAARRLGLVMAKDPAMIRLPDGKISRIPTPGQGHAGVTAQSGLGSAGTPSTGAGQ
>AP019371.1|BBH66941.1|3917753_3918824_+|ribosomal-RNA-small-subunit-methyltransferase-H
MGVVMGEPRGTHVPVLLERCLELLAPGLALPGAVHVDFTLGLGGHAEAVLQRFPDVVLIGLDRDTEALAHARHRLAGFADRTHLVHAVYDELPRVLGELKIPAIHSGLFDLGVSSLQLDEADRGFAYSQDAPLDMRMDQSRGVTAEEVVNSYEPGELVRILRQYGEEKFAPRVVQAIVRERAKARITSTARLAELIKEAIPAAARRTGGNPAKRTFQALRIEVNAELDALEGAVPAALDALAVKGRLVVMSYQSLEDKIVKRALTARARSTGPIDLPVELPGTGPTLRLLTRGSELPSEAEVAENPRAASVKLRAVERIDEQEQGPKYNQAPRTGRERPRMAGPAAGRDQNGRDEK
>AP019371.1|BBH66940.1|3917088_3917520_+|transcriptional-regulator-MraZ
MFLGTHTPRLDDKGRLILPAKFRDELAGGVVITKGQERCLYVFPMPEFQRLAGQLREAPVTNKAARAYSRVFFASAHDEVPDKQGRVTIPAHLREYASLGRDLVVIGASTRVEIWDKQAWDDYLTASEEEFADIEEGVLPGGL
>AP019371.1|BBH66939.1|3915669_3916491_+|hypothetical-protein
MHEHSSRRGRRTSRGAGTVALSLGLCLCAGQLVATASPAAAASTTPVVKVAAASQAAATVKPKLTTKASTRNLKWGSTLKVTAKVIDPRTGKVAKGTVRLQGWRDGKWKTWDTEKVKSGTVTLKAAPKSTAYVRTVFNGSGFSSVTSAKTKIKVKASGAKILAEAKKHKGALYKFGASGPKRFDCSGYTKYVYKKAAGKKLPHKANSQQKYGTKVAKSKKKVGDLIIFRNGSYGYHAGIYAGNGYIYDSPHTGARVGKHKIWSSNYVVRRLVA
>AP019371.1|BBH66938.1|3913895_3915116_-|ligase
MPLIAKVATTASKTAAALSRAAGRGDGSVIGGWIGLKIDPDLLAHLSSGRAVALVSGTNGKTTTTRLTAAALGVLGRVATNSFGANMPTGHTSALAKEGHTPFAVLEVDEHYLPQVIESTKPKVVALLNLSRDQLDRAKEVAMMAQLWKVALANHPSIKVVANADDPMVVWAAASSPQTTWFSAGQRWLDDSFVCPESGHPIERQNGDWWCTGCPLRRPRPQWAVEDEGVIDPRGDWHMVKLQLPGKVNIGNAATALAVAAEFGVRPIEALPRLARVTSIAGRYAQVDRDGRNIRLLLAKNPASWLEAFDMAEQAPTLLSINARDPDGFDTSWLYDVDFSPLRNRPVLITGDRAYDLAVRLQVNQVPFRHVQTFDEALAAVPPGRLEVIANYTAFQDIRAELDRVN
>AP019371.1|BBH66937.1|3913192_3913906_-|glutamine-amidotransferase
MSTESLRIVWIYPDLLSTYGDRGNLLILAHRAAARGIPVETYEVRSDQQMPTTADIYLIGGGEDGPQALAAQRLLTDGGLHRAVNQGAAVLAICAGYQLFGHSFFAKGAKCQGLGLLDITSDRGVTRAVGEIRGDIDPRLGLPPLTGFENHGGRTHLGAHAAPLARVTAGIGNDGQTEGAWAGKILGTYSHGPALARNPAIADLLLRWSTGADRLAPLDDTWADRLRQERLEAASAV
>AP019371.1|BBH66947.1|3927058_3928444_+|hypothetical-protein
MADDRNQKDRPSLSRQLMPAVHGLLARPLSSYYLLIASSGLLLLIGLTMVFSATSVEAYAKNGNAFSEISSQAVYALLGLVAFWVCQRLPAQTLRTLGKYIMGVAVVLLVILAVLHALRSAGITKSLGPIKADLNWLYFGPVSMQPGEIAKVGMVLWGADVIARKGPKLAHWRELAMPLFPVVGLLFVLVGYNDLGTMLVLLALIVGLLWAAGVRMRFFAALGVLGLAGVSLLIAAASRGAGSGATGEPNYRLERLTSFMTPLSECDIDKACYQIIQGRSAIFEGGWFGVGLGKGALKWGWVPEAENDFIFSIVAEELGVVGCAVVLALLSVLAYTGFRIARRSQDPFRRLAASAITTWLVAQAVINMGGVVGLLPITGLPLPFISAGGSALVVTLAAIGMLASFARAEPDAARALNARPTPRWVRLLWAPLPPLPPARRSGPARPPVQKKAVGVGDGRRR
>AP019371.1|BBH66948.1|3928443_3929544_+|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase
MSLRSVVLAGGGTGGHIYPLLAFADALRRHFPNIRITTLGSPKGMENQLIPAAGYDLRNIPAFQLPRSLNLDLLRTPDRMYKSAHAAGEIIDEVQAEVVVGFGGYVSVPAYLAAWRRELPIVIHEVNVPPGVANRMGMKFTKRVAVGFPHQLEQAESLRNARLVGVPLRTGITYMDRPALRPQALYHFGLRPDLPVLFVSGGSSGARTINLAVAAAAKRLAHAGIQVLHVQGGRNDPFEVPNDLPVPYVVVPYLSEMELGYAAADLMLCRGGAITVAETTALGMPAIYVPYPYSNQEQRRNALPVVEAGGGLLVDNSELTPDWIERNIIPIARDRQRLGAMGAAAARYGRRDGDEALLRYVLEAVS
>AP019371.1|BBH66949.1|3929566_3931003_+|UDP-N-acetylmuramate--L-alanine-ligase
MNTAELTPAGELTAEDLGSVHLIGIGGVGMAGLARLLLTRGVPVSGSELREWPALTALRALGGTVHMSHVASNLDGVDTVVYSTAIPQDHIELAEARRRGLRVLHRSEALAVAMTNRQGIAIAGTHGKTTTTSIMTVILQHAGQDPSFVIGGEISAAGAAGHHGTGPHFVVEADESDKSFLIYRPHVAIITNIEGDHLNNWGDLESLKAGFLEFGSLADGFVVTCADGPGTDELIAGLKAEGKTVYTYGESESADLRISDVVSSTSGVRYQAVLDGKPLGEVKLALPGKHMGLNSAATVLTALKLGLPLDKVIEALESFPGVRRRFERKGIAAGVRVYDEYAYHPTSVQAALRTLREVAGDGRLLVVFQPYRVYRTRDLQAELAEGLAVADEVICMEVFGPGETRGPGEGGRALTAAIDLPDDRKVFVPDWDDVPAEVVRRSRPGDVVVTMGAPPISLMGDELLAALAEADQQPDLAR
>AP019371.1|BBH66950.1|3931007_3931775_+|cell-division-protein-FtsQ
MTGGGNRNWRLVRANTDAVPSSARRFMARARQRKLKAAMPWLIGAGVLLAVGGLVWLVYGTAVLGVRQVEVVGTELLDPEQVRQAAAIPDNRPLARVDLGAAGARVRELPAVDRVVISRSWPSTVVIEVIERTAVAAVPAKQGFILIDDEGVPFRAVKEQPSGLPLARLSAPGPFDTNTESALAVLAALSDELRRQLVAVAVPSPVQIRLELRKGRVVIWGDDTKSDEKSKVATELLGQKGEEIDVSAPTVVTIR
>AP019371.1|BBH66951.1|3932051_3933170_+|hypothetical-protein
MTPPHNYLAVIKVVGIGGGGVNAVNRMIEVGLKGVEFIAINTDAQALLMSDADVKLDVGRELTRGLGAGAQPDVGKNAAEDHRDEIEEVLKGADMVFVTCGEGGGTGTGGAPVVANIARKLGALTIGVVTRPFSFEGKRRQVQAEAGIDELRNQCDTLIVIPNDRLLALGDRGISMMDAFRQADQVLLSGVQGITDLITTPGLINLDFADVKSVMSNAGSALMGIGSARGDNRAVEAAERAISSPLLEQSMDGARGVLLSIAGGSDLGLFEINDAAQLVTDAAHPDANIIFGAVIDDALGDEVRVTVIAAGFDGGTPSYKPAEPVRKVVPQPSAPPVSAPVSPPPVQPAATPPPRRVLFDDVDVPDFLKNGS
>AP019371.1|BBH66952.1|3933178_3933889_+|YggS-family-pyridoxal-phosphate-enzyme
MERDERRRAELAANLVQVNDRIARACEAAGRPVESVTLTAVTKTYPASDVALLAGLGITDVGENKDQEAAAKAADLTAAGVRLRWHFVGQLQRNKVKSVVSYADVIESVNSERLAEALGRATAGRAVPLDVLIQVSIDGDPARGGVIENDLWRVSDTVTSSDGLRLAGVMAVAPLGWDPDRAFERLALLAGGLAERYPGATTVSAGMSGDLEAAVRHGATHVRIGTSLLGMRNSLR
>AP019371.1|BBH66953.1|3933948_3934821_+|hypothetical-protein
MAVASYDAASQRVVGPNRIRVFGSHKGGRGTPKGARAAQRTRRWGHGRSARRAGMSALRKAGVWLGLVEEDDDRGYDDRGYRESSYRDRGRERERDRYAGDRDRYADEFAEDDDEEERAVPRARSERTRLDRVSAARADLDREESERLDRASVRSITRPQPAPEQSNAMSYSTRDNLALKPQQQAQPQPQPRQVEEEQRYQITTLHPTTYREARTIGEHFRDGVPVIINLTEMDESDARRLVDFAAGLAFGLRGTIERVTNRVFLLSPANVQVTAEDKAKIAEGGFFTQS
>AP019371.1|BBH66954.1|3934844_3935150_+|YggT-family-protein
MLSIVFQILYISLYLFFVVLLARFVLGAVLQYGRRWQPSRGASAGLESVWSVTDPPLKALRRVIPPLRIGNVSLDLASIVLLVILFVLMNFVLVPLIKTYS
>AP019371.1|BBH66955.1|3935193_3936006_+|cell-wall-synthesis-protein-Wag31
MPLTPADVHNVAFKKPPIGKRGYDEEEVDAFLDEVERELARLIEENNELRAQVERGGRGGAPVAPGADPRMAAELNDLKAQLDRVQRDKSAAEQAARQMQAELEQVRAQGPGPGAGAAGADGEQQALRVLMMAQRTADDHVSDARREADKLLSDARSKAEEVTREARAKADALERDARQRHQEAMGGLDAKRTALQKHIEELKQFEREYRTRLKAYLESQLRDLDGRGQGLEAELTRADSGRAVGGSGGLAAAGLAGSYGGRANSIESGR
>AP019371.1|BBH66956.1|3936048_3936954_+|hypothetical-protein
MIVASLLLIPVAVVFLALGFINGSSSLLIAAIVVSLLIAVALVLSARQAATRRVPARESDRLRDPGWEERPGPMPEPQTPDSPQYSSSAEYSESAAYSPSAQYAESAQYAGGEDSSDPYAGNSASAETTFAGESALADQVGAAVPEPEHPGPADDEEAWEPAERAHYADSDSAPDYDHAASTIGAARAPESEDPSWRRPAEAEDRSDEGQQPDEFGEPDDDDPDDEPLPQSVRPADAVLVARLDAEVLVVDGRPRYHMADCPHLVGRLTEPLPVNEAVELGFSPCGLCRPVDRLVAAVAPH

Crispr_ID: AP019371_8

• CRISPR_ID: AP019371_8
• CRISPR_location: 4629362-4629495
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_8

Consensus_repeat	Method
GCGCACGCGCTCCTGGGTTGTGTGCGTTGGCG	CRISPRCasFinder

spacers of AP019371_8

>8.1|4629394|70|AP019371|CRISPRCasFinder
GCCCGTGTGGCGGCGGTGGGCGCACGCGCTCCTGGGTTGTGTGCGTTGGCGGCCCGAATGGGGGCGGTGG

CRISPR arrays and Neighbor proteins around AP019371_8

CRISPR arrays

The CRISPR arrays of AP019371_8

>merge|AP019371|8|4629362-4629495|CRISPRCasFinder
GCGCACGCACACGAGGGTTGTGTGCGTTGGCGGCCCGTGTGGCGGCGGTGGGCGCACGCGCTCCTGGGTTGTGTGCGTTGGCGGCCCGAATGGGGGCGGTGGGCGCAAGCACACCTGCGCTGTGTGCGCTGGCG

>AP019371|8|6|4629362-4629495|CRISPRCasFinder
GCGCACGCACACGAGGGTTGTGTGCGTTGGCG	GCCCGTGTGGCGGCGGTGGGCGCACGCGCTCCTGGGTTGTGTGCGTTGGCGGCCCGAATGGGGGCGGTGG
GCGCAAGCACACCTGCGCTGTGTGCGCTGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH67568.1|4625762_4625957_-|ferredoxin	unknown	unknown	gnl|CDD|224064
AP019371.1|BBH67582.1|4638422_4639052_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
AP019371.1|BBH67570.1|4627420_4627789_-|hypothetical-protein	unknown	unknown	gnl|CDD|236975
AP019371.1|BBH67580.1|4635453_4635855_-|dynein-regulation-protein-LC7	unknown	unknown	gnl|CDD|367422
AP019371.1|BBH67567.1|4624804_4625581_-|hypothetical-protein	unknown	unknown	gnl|CDD|259816
AP019371.1|BBH67564.1|4620951_4622055_+|2-heptyl-3-hydroxy-4(1H)-quinolone-synthase	unknown	unknown	gnl|CDD|235874
AP019371.1|BBH67565.1|4622128_4624192_+|hypothetical-protein	unknown	unknown	gnl|CDD|143635
AP019371.1|BBH67563.1|4619760_4620897_+|hypothetical-protein	unknown	unknown	gnl|CDD|379258
AP019371.1|BBH67569.1|4625985_4627170_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
AP019371.1|BBH67574.1|4630831_4631902_+|prenyltransferase	unknown	unknown	gnl|CDD|260107
AP019371.1|BBH67566.1|4624199_4624679_-|hypothetical-protein	unknown	unknown	gnl|CDD|378330
AP019371.1|BBH67579.1|4635098_4635464_-|hypothetical-protein	unknown	unknown	gnl|CDD|283084
AP019371.1|BBH67578.1|4634515_4635070_-|ATP-binding-protein	unknown	unknown	gnl|CDD|367304
AP019371.1|BBH67571.1|4627951_4628782_-|hypothetical-protein	unknown	unknown	gnl|CDD|350097
AP019371.1|BBH67581.1|4635851_4638218_-|histidine-kinase	unknown	unknown	gnl|CDD|377989
AP019371.1|BBH67575.1|4631894_4633277_+|tryptophanase	unknown	unknown	gnl|CDD|237314
AP019371.1|BBH67573.1|4629831_4630419_-|isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl|CDD|235156
AP019371.1|BBH67577.1|4633783_4634191_+|glyoxalase	unknown	unknown	gnl|CDD|319924
AP019371.1|BBH67572.1|4628974_4629232_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH67576.1|4633489_4633735_+|hypothetical-protein	unknown	unknown	gnl|CDD|197666

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH67568.1|4625762_4625957_-|ferredoxin	gnl|CDD|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	7.75922e-10
AP019371.1|BBH67582.1|4638422_4639052_+|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.57542e-09
AP019371.1|BBH67570.1|4627420_4627789_-|hypothetical-protein	gnl|CDD|236975	PRK11770, PRK11770, YccF domain-containing protein.	4.68895e-45
AP019371.1|BBH67580.1|4635453_4635855_-|dynein-regulation-protein-LC7	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	1.55162e-15
AP019371.1|BBH67567.1|4624804_4625581_-|hypothetical-protein	gnl|CDD|259816	cd13438, SPFH_eoslipins_u2, Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes a subgroup of the stomatin-like protein family (SLPs or slipins) that is found in bacteria. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Bacterial SLPs remain uncharacterized.	5.59518e-65
AP019371.1|BBH67564.1|4620951_4622055_+|2-heptyl-3-hydroxy-4(1H)-quinolone-synthase	gnl|CDD|235874	PRK06847, PRK06847, hypothetical protein; Provisional.	6.29199e-44
AP019371.1|BBH67565.1|4622128_4624192_+|hypothetical-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.70829e-50
AP019371.1|BBH67563.1|4619760_4620897_+|hypothetical-protein	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	1.51825e-15
AP019371.1|BBH67569.1|4625985_4627170_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.69718e-85
AP019371.1|BBH67574.1|4630831_4631902_+|prenyltransferase	gnl|CDD|260107	cd13930, PT-Tnase, Aromatic Prenyltransferases (PTases) associated with tryptophanase. This group of bacterial and fungal proteins shows homology to the DMATS/CymD family of ABBA prenyltransferases, which prenylates indole, tyrosine, and xanthone derivatives. Some of the members, mostly fungal proteins, are associated with tryptophanase-like domains (Tnase) which catalyzes the degradation of L-tryptophan to yield indole, pyruvate and ammonia, or the degradation of L-tyrosine to yield phenol, pyruvate and ammonia. This suggest that these otherwise uncharacterized proteins may exhibit multiple functions.	1.69123e-126
AP019371.1|BBH67566.1|4624199_4624679_-|hypothetical-protein	gnl|CDD|378330	pfam09969, DUF2203, Uncharacterized conserved protein (DUF2203). This domain, found in various hypothetical bacterial proteins, has no known function.	4.25339e-46
AP019371.1|BBH67579.1|4635098_4635464_-|hypothetical-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	3.57211e-19
AP019371.1|BBH67581.1|4635851_4638218_-|histidine-kinase	gnl|CDD|377989	pfam08376, NIT, Nitrate and nitrite sensing. The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.	1.63226e-26
AP019371.1|BBH67576.1|4633489_4633735_+|hypothetical-protein	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	3.01745e-21
AP019371.1|BBH67575.1|4631894_4633277_+|tryptophanase	gnl|CDD|237314	PRK13238, tnaA, tryptophanase.	0
AP019371.1|BBH67573.1|4629831_4630419_-|isopentenyl-diphosphate-Delta-isomerase	gnl|CDD|235156	PRK03759, PRK03759, isopentenyl-diphosphate Delta-isomerase.	1.29682e-88
AP019371.1|BBH67577.1|4633783_4634191_+|glyoxalase	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.814e-36
AP019371.1|BBH67571.1|4627951_4628782_-|hypothetical-protein	gnl|CDD|350097	cd08983, GH43_Bt3655-like, Glycosyl hydrolase family 43 protein such as Bacteroides thetaiotaomicron VPI-5482 arabinofuranosidase Bt3655. This glycosyl hydrolase family 43 (GH43)-like family includes the characterized arabinofuranosidases (EC 3.2.1.55): Bacteroides thetaiotaomicron VPI-5482 (Bt3655;BT_3655) and Penicillium chrysogenum 31B Abf43B, as well as Bifidobacterium adolescentis ATCC 15703 beta-xylosidase (EC 3.2.1.37) BAD_1527. It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 includes enzymes with beta-xylosidase (EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanases (beta-xylanases) and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	1.76322e-45
AP019371.1|BBH67578.1|4634515_4635070_-|ATP-binding-protein	gnl|CDD|367304	pfam03029, ATP_bind_1, Conserved hypothetical ATP binding protein. Members of this family are found in a range of archaea and eukaryotes and have hypothesized ATP binding activity.	3.64043e-38

Protein sequences

>AP019371.1|BBH67572.1|4628974_4629232_-|hypothetical-protein
MRSPPDPRQLGTANAHKTTTRVRSPPDPGRSGTAGAHNAGVRALAAAIRAAGAHSVGVRALTGWPEAVGAASAASTRTGEERATH
>AP019371.1|BBH67571.1|4627951_4628782_-|hypothetical-protein
MLALVLGALAIPQPAAAASTLIYSTFKGDGAADQELWIYQSTNGGTTYSVLSDTNFRGPTGVLRDPSILKYNGRYYIAYTVQSWTTNSTYFNIATSTNLTSWSNVASVPAGISGANYTWAPEFYVENGVVRIITSVASTACAWCFRPYVYTAQNTALTSWSGPSQMWGLGTNHIDTFVVKSGSTWHAFTKNETTKYIEHWTTTANLYEGWVNKGTLWSSGYEGPSLVKLDDGRWRIYVDKYTNGGVWTATSSDLNTWTGLSAVGCSGCRHGTATVK
>AP019371.1|BBH67570.1|4627420_4627789_-|hypothetical-protein
MILNVLWFIFFGWALALAYLLAALISFILIITIPFGVASLRLAIYSAWPFGRTIVDDPGAGIASGLANIVWLILFGWWIALAHIAAGIAQCVTIIGIPFGIANFKLVPAALWPLGRQIVDAP
>AP019371.1|BBH67569.1|4625985_4627170_-|cytochrome-P450
MDADLPTYPFPQPAALDPPPEWDELRSQCPVSTVRLASGDEALLLTRYADVRQVLSDPRFTRLLDADGAARVTAQESGGVFGAEQASKTPMGEAHQRWRRLVGRYFTAKRMSALQPRIAAMADQLIDGMTARPQPADLVRSFGFPLPVWVICELLGAPDRDRDRFSYWSDTMLSLTRYKQEEIDAAQLEFGEYLWQLIEEKTAHPGDDLISDLVEEFSPIELIGTAQGLLIAGHETTANMIGKMVAMLLADRSRWESLLASPTLVRTAVEEALRFDANPGFGMPRYITEDIEVDGVTLPAGSTVISSMASANRDETAFDGASGMDLARSPNPHLAFGAGPHSCIGQALARTELQTALTALLDRLPGLRLAQPAADLPRREGLIIGGLEKVLVTW
>AP019371.1|BBH67568.1|4625762_4625957_-|ferredoxin
MKVTVDREVCCGAGQCVLLAPEVFDQDEDDARVLLLAPSPGPADQAATEDAAAVCPTGAISIMR
>AP019371.1|BBH67567.1|4624804_4625581_-|hypothetical-protein
MPEVIVRSGTRGLKYLDGRLDAVLEPGRYRLPRRARIEITHVDLRERELNIKGQEILTADKVAVRVNIITHFRVTDPVAAVERVADYADRVYSDVQLAARRSLASMTLEAILTNRNQLSEDILRDVEGVSATYGVQIIRADVKDLVFPGNLQDVMNRVLTAQRMAEAQMVEARTRADREALEASARAESTRLAAEADATAKRIRADAEVDALRRLAEAAEAYARHPALLRLRELETLGALGANAEARLYIGFDKHVEP
>AP019371.1|BBH67566.1|4624199_4624679_-|hypothetical-protein
MQSAGAATVAPTPSALRRPGAPTEAAGGLLCHTSGMGLFTLPQARSELERLRPVLDEIVTIRADLVELSAALTPGGAPTDLGGLPERKAAEARLNELMTEVQQTGAELKGVAPLLVDFPADLDGVPVLLCWLEGDTDLAWYHRADLGFAGRRRLPATAG
>AP019371.1|BBH67565.1|4622128_4624192_+|hypothetical-protein
MGAAGGEDRDRSATRWMRGAFATFYLVLAITNLLLLDGFAQVSTVFLATFTGLLLAVAALWRRDWSDHLGYVPVVNGVAQVALTGEIHWTTTLMLTLVCVAAAVPRRTFLGATVLGCAGWVASVAWVPSLRVTDLAYWVVQLFIAALVAAILHEALRRRQRQLRLARDEISAVADRFGSLFHASPSGVAIADENDVIVAVNQAFCDLVGLPEEKLIGVDCAAFSSAVPSSAVSSSAVSSSAVPSSAVPSSAVPSSAVPSSAVPSSAVPPEPSAAQASAAQSGPVAVPPEPPAGSSVFAAPPLTDLSGGSPSAGVGFERRLERPDGTVRWVWSAVGRSTDRVLIQLQDVTDRHLAEAAMRESDRLLAAVSQAARRIRTGEDARSTIIDAVRELAEADSVSLMEPLTAQALVVTGAAGAQVLGTLIPLNGSSMTARVYVDGQPVFLADATQDPRVSPALLALVDGRSMMWQPVIADGVVVAVLVVGWTRRVASVGDHRARAVAMLADETALALEHERLLRRLEQMAFTDTLTGLPNRRAWQSRLATLFAQDCPLAVAIADLDRFKRYNDTHGHLLGDELLQRTAEAFAAELHGDDVIARWGGEEFVIALPGRTTSSAFEVLERVRLATPDEETCSIGYAVWDGTESAERLLERADAALYQAKDNGRDMVQAAEVPAAEVPASATAGRGR
>AP019371.1|BBH67564.1|4620951_4622055_+|2-heptyl-3-hydroxy-4(1H)-quinolone-synthase
MVGGGIAGLAAARALRERDIPVEVAERGGARSDGLAINLPGNAITALTALGVGDGLRRLGRPTGRREYRSARGRLLFAVDEDAFWGSDARPRCVRRSDLLALLTGGLDVAVRRATVREVRPSSRTEVLFEGGERADYGFVVGADGVRSVVRAAVTDQSGVRSSLLSAASWRFMAPNPGVDCWTVWSGAGGAFLLIPVDDHEVYGYASGVRGGAIGGSPEWLRETFGGYPSPVRSVLESITELYHSPIEEVRALRWSSGRCVLIGDAAHATAPIWAQGAALAVEDALVLAALLAGDAREPGGGWDTVGARFEQRRRGRVTHVQEATDRFSRAAGLPTWLRNPLLPVIGPRVYRETYSALRTLDIHPPR
>AP019371.1|BBH67563.1|4619760_4620897_+|hypothetical-protein
MPTDLAPAMRPRLPATVDAIATAVEDTAAEAAGNAKFARDVRNAVQVALDRFLDLAGTGEPALPPKIREVFVALGAGEARENRGPEMLLGALRTAARLMLRTASESLAAQRPITVDELIDLADATSAYADELAAACTDGLARQLREQAGEGDRRRRQMADLLLRGGAPSEVARDAASSIGWPALDTIVPVLLPPDQARDARFRFGADGVVTERGRDAVLLLRGGPRAERTALTEALQGREAVVGPALGWAEVPEAVRLAERTAELVRPASEPIFADDHFAALALRGETGALAVLSARRLAPLVGLRAGQREQLLVTLESWLRHWGSRTSVAAELFVHPQTVSYRLNRLRDLIGDDLDDPAARFELLLVLAYRSRPTSI
>AP019371.1|BBH67573.1|4629831_4630419_-|isopentenyl-diphosphate-Delta-isomerase
MEHVILLDESGTAIGLADKQTVHTDSTPLHLAFSCYIFDSAGRFLVSQRALAKKTWPGIWTNSVCGHPAQGEAMTDAVRRRARFELGLDLGEIRLVLPSFRYRAELDGIVENEMCPVFHATVDDDPAPNPDEVESTRWVPWESFIATALTDDAYSPWCRLQIAELTALGATPASWPAGDPAGLPPAASAVESAPA
>AP019371.1|BBH67574.1|4630831_4631902_+|prenyltransferase
MQDLSVFDHLGGQLRRLCDVVGMDPATPVELLSELLGDYGSRPLSEPPAWPSDVSDDHTPVEFSIAYNESEPPALRILAEALGSTPGVRANALATYEFLRRQSQRFGLSTSRLDAVRDLFDAENPQGDFVLWISLVFRSGRAPEFKVYFNPELSGAEQAPDVVRRALDRLGLGPAYEKMLSQAIRPAELGRRDRLTFFALDLHDGPQARVKLYISHHDARAEDVARASSVVDGVDPELVAGFCEQAGRTPLFTGRPLVGSFTITQGADRPNGYSVYVPIRSYVTDDQEALERVLPLLDRYRFDPAVLDKAIAAVTSRTLDSDAGLIAHVSLRLGPPRPGMTVYLSSEAYRGVSLNV
>AP019371.1|BBH67575.1|4631894_4633277_+|tryptophanase
MSSDLEIPLPPPYRIKVVEPIAFLSPSERREAIEAAGYNPFNLRSDQIAVDLLSDSGTGATSAAQEAAAAQGDESYAGARSWFRFRDEAADLTGYPHLLPVHQGRAGERVLFSGLLKPGQICVSNTHFDTTHANVILAGGKPVDLPVAAAFDLDSPEPFKGNIDLQALEELLAGPSDVGVVLMTITNNGLGAQPVSMANLEAVRNLCQLYRVPFFLDAARFAENAWLVQQREPGYQGWSPRQIATRAFQLADGCLISLKKDGLTGIGGLIGLRDDALFAQCEANLIATEGFSTYGGLSGRDLERLAVGLREVVDPLYLAGRAGQTERFAQMIRDAGVSIVEPAGIHALYLNAGRLLPHLTPAEFPGHSLGCQMYLDGGIRSAELGSLYLGTLDAAHRLVSPAPFELVRLAIPRRVYTSEHFEYVAAVLGAIAKDPERIRGYRIVSAPPLLRHFKVRLAPL
>AP019371.1|BBH67576.1|4633489_4633735_+|hypothetical-protein
MFGETPHRYLQRRRVERAMFLLRSSPESVTDICYKVGFNSLGTFSRTFREIVGVSPRAYRRSSPPLPAAPNCFAMAWTRPN
>AP019371.1|BBH67577.1|4633783_4634191_+|glyoxalase
MFTAITHSQIYVLDQDEALGFYVGKLGLDVNTDADLGFMRWLTVNVPGHPDRQILLSLPGGPSMSAETAAQIRSLLTKGALCGTHILTTDDCRKTYETLLSRGVEFTEEPTERPYGIDCGFRDPFGNHIRMTQPL
>AP019371.1|BBH67578.1|4634515_4635070_-|ATP-binding-protein
MNRTSVKIVIAGGFGTGKTTLVSSVSEIAPLTTEELLTSASIGIDDVTGVESKTHTTVALDFGRITISPDVVLYLFGTPGQDRFWFMWDELAQGALGAIVLVDTRRLDTSFPAIDYFERRGIPFVAAVNRFFGECEYTEDEIRSALELTPEVPLVWLDARDRTSSKLALISLVRHAMARIPQPS
>AP019371.1|BBH67579.1|4635098_4635464_-|hypothetical-protein
MTGEAWDGDDETAAGRFVPLYVLVNGRTSPRDTNLDLATQVIAVPVDASRLEPEYLQILGRCGSWISIAEIGAYLHIPLTIVKVMVDVLLEQGYLDSGAPAQHKVVDMRLLNAVLAGLERL
>AP019371.1|BBH67580.1|4635453_4635855_-|dynein-regulation-protein-LC7
MTHPASSIDLPWMLDDLVEVPQVVSVVVLSTDGLIVQKSTQMQQDLAEILAAGASSMYSVAAGTGRHFKSGGVQQVVIEFHEHTLFIAAAGQNARLAVLCEQDVDMGMVAYEVSRLVTRIGDYLSAPARSNDG
>AP019371.1|BBH67581.1|4635851_4638218_-|histidine-kinase
MNVAPSPADQSTETPGRTRRQQSIKRRVVRLVLVPSVVALLIWFGASGYLIFQGFYNRAIAISVREVSIPAVSALSSIQQERRLSVAYLARPSTNLNALLEQRRQSDQQLDELREVADGALSAAPASIKNQWSTLVGYLDQIPTQRSAIDARSTTASRAYDFYNELLDAATAMFDTQARITPDSTAALGGVTSVELFSASDAMSRAASTMDGAYAAKTFGRADYLDFVSLVSEYRATLEEIRDNLEPTVRERLQTMEASSAWQNLSAAEDSIIASGPWKKSVPNAVTMNRDRWAMVTGTVSQSLVDLTIDEADQVSARTLRTGNNQLLTALAGSLVALAIAIGVIFWALRSSAVLVDRALSTRLSRLGEDAGALVDTRLPAVMDRLRKREAVDLETEFAAKDYGADEIGQVADVIHRSITVAAEAAVDEAKARAAGTAMLMGVARRPQRPLQRGLKVIEDLQGQIGDEKLLTHLFDIHHQLNQTRRFLENLVILAGGQIGRRFSKPVPLRRVLLASFAEARDYQRINLRGATDVALVGYAVAEVIHLMAELLDNALAFSPPGTTVWVTSSRAQHGVAVEIEDAGVGMSQENIDRANTLLATAPTPEVTELKDGSQVGLYVVAELAKREGLQVSLRRSAYGGLLAIVLLPERLLISNSEPDEDTGAVITPVPTPAVPPAREEGPIAVLEKPVRVEVQPEKPKPVTRTPAALEKAQPGSKPPLPHRRPQQHLAPGLRETPPGEPEAPEPAPAPRSPEEARNRFARYQRGWAEGQNAPTETETTFEQGRNE
>AP019371.1|BBH67582.1|4638422_4639052_+|TetR-family-transcriptional-regulator
MPKIVDHHARRNEIVEAYLAVVARDGMPAATSRAIAAELGVGAGGLWHYFDGFDDVAAAAYQRISERTNARLAAFTAGLRGLAAVRAMLHEICPLEKETVDEAYVVVGFWGRLAEGSRISAGADVGEQWSALVRTHLAEAVEDGELIAATPIDDVAEVLFAVGMGQQALAIMRSPLAEPSRQLASIEHCLRPWLVVSPTVPMGTLPQLH

Crispr_ID: AP019371_9

• CRISPR_ID: AP019371_9
• CRISPR_location: 4654371-4654572
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of AP019371_9

Consensus_repeat	Method
CGGNGGNNCAGTGGTGCGGTGG	CRT

spacers of AP019371_9

>9.1|4654393|30|AP019371|CRT
GTGCGGTGGTGCGCCTGGTGCGCCTGGTGC
>9.2|4654445|18|AP019371|CRT
CCCGGCGGCCCGGCGGCC
>9.3|4654485|26|AP019371|CRT
TGTGGTGGTGCGGTGGCGTGGTGGCC
>9.4|4654533|18|AP019371|CRT
CGTGGTGGCGTGGTGGCC

CRISPR arrays and Neighbor proteins around AP019371_9

CRISPR arrays

The CRISPR arrays of AP019371_9

>merge|AP019371|9|4654371-4654572|CRT
CGGCGGCCCAGTGGTGCGCCTGGTGCGGTGGTGCGCCTGGTGCGCCTGGTGCGCCTGGTGCGGTGGTGCGGTGGCCCGGCGGCCCGGCGGCCCGGCGGCCCAGTGGTGCGGTGGTGTGGTGGTGCGGTGGCGTGGTGGCCCGGCGGCCCAGTGGTGCGGTGGCGTGGTGGCGTGGTGGCCCGGTGGTGCAGTGGCGTGGTGG

>AP019371|9|2|4654371-4654572|CRT
CGGCGGCCCAGTGGTGCGCCTG	GTGCGGTGGTGCGCCTGGTGCGCCTGGTGC
GCCTGGTGCGGTGGTGCGGTGG	CCCGGCGGCCCGGCGGCC
CGGCGGCCCAGTGGTGCGGTGG	TGTGGTGGTGCGGTGGCGTGGTGGCC
CGGCGGCCCAGTGGTGCGGTGG	CGTGGTGGCGTGGTGGCC
CGGTGGTGCAGTGGCGTGGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH67593.1|4647926_4649162_-|arginine-deiminase	unknown	unknown	gnl|CDD|234949
AP019371.1|BBH67592.1|4647232_4647925_-|hypothetical-protein	unknown	unknown	gnl|CDD|225006
AP019371.1|BBH67594.1|4649176_4650577_-|amino-acid-APC-transporter	unknown	unknown	gnl|CDD|163522
AP019371.1|BBH67601.1|4658776_4659973_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|226618
AP019371.1|BBH67603.1|4661089_4662034_-|hypothetical-protein	unknown	unknown	gnl|CDD|377929
AP019371.1|BBH67598.1|4656022_4656853_-|spermidine/putrescine-ABC-transporter-permease	unknown	unknown	gnl|CDD|224098
AP019371.1|BBH67588.1|4644419_4645361_-|hypothetical-protein	unknown	unknown	gnl|CDD|225443
AP019371.1|BBH67600.1|4657733_4658780_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
AP019371.1|BBH67599.1|4656849_4657737_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224097
AP019371.1|BBH67604.1|4662045_4662399_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224639
AP019371.1|BBH67590.1|4646404_4646623_+|hypothetical-protein	unknown	unknown	gnl|CDD|378163
AP019371.1|BBH67591.1|4646631_4647216_-|hypothetical-protein	unknown	unknown	gnl|CDD|224276
AP019371.1|BBH67605.1|4662489_4663344_+|hypothetical-protein	unknown	unknown	gnl|CDD|379270
AP019371.1|BBH67587.1|4642730_4644389_-|DEAD-box-ATP-dependent-RNA-helicase-CshA	unknown	unknown	gnl|CDD|223587
AP019371.1|BBH67596.1|4653534_4653969_+|hypothetical-protein	unknown	unknown	gnl|CDD|119345
AP019371.1|BBH67606.1|4663343_4668065_+|DNA-binding-protein	unknown	unknown	unknown
AP019371.1|BBH67602.1|4659975_4660959_-|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
AP019371.1|BBH67597.1|4654813_4656022_-|D-mannonate-dehydratase-CC2812	unknown	unknown	gnl|CDD|237901
AP019371.1|BBH67589.1|4645357_4646329_-|hypothetical-protein	unknown	unknown	gnl|CDD|379634
AP019371.1|BBH67595.1|4650633_4653450_-|hypothetical-protein	unknown	unknown	gnl|CDD|377950

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH67593.1|4647926_4649162_-|arginine-deiminase	gnl|CDD|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
AP019371.1|BBH67592.1|4647232_4647925_-|hypothetical-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	4.0476e-16
AP019371.1|BBH67594.1|4649176_4650577_-|amino-acid-APC-transporter	gnl|CDD|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	1.73424e-157
AP019371.1|BBH67601.1|4658776_4659973_-|ABC-transporter-substrate-binding-protein	gnl|CDD|226618	COG4134, COG4134, ABC-type uncharacterized transport system, periplasmic component [General function prediction only].	5.33567e-62
AP019371.1|BBH67603.1|4661089_4662034_-|hypothetical-protein	gnl|CDD|377929	pfam07853, DUF1648, Protein of unknown function (DUF1648). Members of this family are hypothetical proteins expressed by either bacterial or archaeal species. Some of these are annotated as being transmembrane proteins, and in fact many of these sequences contain a high proportion of hydrophobic residues.	0.00284321
AP019371.1|BBH67598.1|4656022_4656853_-|spermidine/putrescine-ABC-transporter-permease	gnl|CDD|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	8.48277e-46
AP019371.1|BBH67588.1|4644419_4645361_-|hypothetical-protein	gnl|CDD|225443	COG2890, HemK, Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis].	2.11108e-31
AP019371.1|BBH67600.1|4657733_4658780_-|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	3.71961e-138
AP019371.1|BBH67599.1|4656849_4657737_-|ABC-transporter-permease	gnl|CDD|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	1.92442e-36
AP019371.1|BBH67604.1|4662045_4662399_-|GntR-family-transcriptional-regulator	gnl|CDD|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	2.60822e-26
AP019371.1|BBH67590.1|4646404_4646623_+|hypothetical-protein	gnl|CDD|378163	pfam09360, zf-CDGSH, Iron-binding zinc finger CDGSH type. The CDGSH-type zinc finger domain binds iron rather than zinc as a redox-active pH-labile 2Fe-2S cluster. The conserved sequence C-X-C-X2-(S/T)-X3-P-X-C-D-G-(S/A/T)-H is a defining feature of this family. The domain is oriented towards the cytoplasm and is tethered to the mitochondrial membrane by a more N-terminal domain found in higher vertebrates, MitoNEET_N, pfam10660. The domain forms a uniquely folded homo-dimer and spans the outer mitochondrial membrane, orienting the iron-binding residues towards the cytoplasm.	6.71129e-21
AP019371.1|BBH67591.1|4646631_4647216_-|hypothetical-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	8.70932e-19
AP019371.1|BBH67605.1|4662489_4663344_+|hypothetical-protein	gnl|CDD|379270	pfam13569, DUF4132, Domain of unknown function (DUF4132). This domain might be involved in the biosynthesis of the molybdopterin cofactor in E.coli.	6.42061e-28
AP019371.1|BBH67587.1|4642730_4644389_-|DEAD-box-ATP-dependent-RNA-helicase-CshA	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	6.76082e-160
AP019371.1|BBH67596.1|4653534_4653969_+|hypothetical-protein	gnl|CDD|119345	cd06553, ASCH_Ef3133_like, ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation, RNA-processing and the regulation of prokaryotic translation.	5.33228e-46
AP019371.1|BBH67602.1|4659975_4660959_-|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.76746e-100
AP019371.1|BBH67597.1|4654813_4656022_-|D-mannonate-dehydratase-CC2812	gnl|CDD|237901	PRK15072, PRK15072, D-galactonate dehydratase family protein.	0
AP019371.1|BBH67589.1|4645357_4646329_-|hypothetical-protein	gnl|CDD|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	1.46698e-58
AP019371.1|BBH67595.1|4650633_4653450_-|hypothetical-protein	gnl|CDD|377950	pfam07971, Glyco_hydro_92, Glycosyl hydrolase family 92. Members of this family are alpha-1,2-mannosidases, enzymes which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation.	1.87928e-136

Protein sequences

>AP019371.1|BBH67596.1|4653534_4653969_+|hypothetical-protein
MTAAASFWQASGLTGEYTVERFGDSAPLADALLELVLSGHKRATASLVRQFGASPLPRIGVHWIVCDGAGQPRVVLRTVSLRLGPFLSVTADFAHAEGENDRTRDGWLAAHRAYFTRVCGGAFDEETEEVLFERFEVAYRPEQA
>AP019371.1|BBH67595.1|4650633_4653450_-|hypothetical-protein
MPLRHWLAAGLAVLLSPSPASAAPAELDPFDAVDQFIGTEFDTTQNKSNDAYGNTFPGAALPFGMVQPSPTTYKPGNALVGEKGGYEYTANLIRGFGMTRYSGTGCTGRYGGYEFPTIPYAGDTLPVNPSADIKGYYLGFDHANEVAEPGYYRVTTDNGITTELTATTRTAVARYDFAAKSTLIVDVSGPNNRTFGSEVTIDPATRTVSGWMFGADVCDVGNTYKAYFSTTYDQPFTGYGTWNDADLTPGSTHAVKAGTDTSVDYRHDTGAWVTFADGVAVTAKTGFSYVSVANAAANRDRETKKKTIEDIRGDARRAWEKALGTVDVKGGTDEQRIKLYTALYHSFLHPNIRDDVNGEYLGYDKRLHTIGRNEHFYQNLNFAGSGWDMYRSQAQLIALTFPDVAQDLSRSIVAMVQQTGSWAPGTARMQGDNYQVVLATLDDMGATGYDREAALASMVATQRLPATRTTRSEAFQYFATGMIENRKGDFATSRVLEYAVDDFAISQLAERLGDTANRDFFLARSQSWMNVFDPVTGHIRPRERTGFDRSFDLRVREDGAGRGQFNQSTGYQYGWMVPHNMATLIAKRGGADAATAALDVLMADLDSGAYTKTGNYLSNQAAFGTPWVHHWLGQPAKTTDVLYRAVTEMYDTTPSGLPGNDDQGSLSAWYVFANIGLYPAIYGTGDLLVSAPMFDRVTIGKLKIKAHGVAAGKRYTTGLRVNGRTQQANWIPARTTGTLDMTVSATPGDWGKVTPRSWTGGADARNNIGTTPDGQGSLGSLDLSDWSLSRPQLAQAGAAPGAKIGAFTWPDTAPGEPDNWIPHGQRIDLQDAAATSVSFLGLATNGPATGVARVEYTDGTSQDVSVTFGDWAAAAPSGNIAMVTLGGRNNAGGTSGSGTFRIFATTPAALDPTKIVDAVVLPESTDRGVMHVFDVAVS
>AP019371.1|BBH67594.1|4649176_4650577_-|amino-acid-APC-transporter
MTATETTTTQKLTLLTMTSMVVGGMVGAGVFSLPRRFAEETGVIGALIAWLIAGAGMLMLAFVFQTLAMRKPDLDAGVYAYAKAGFGEYLGFFSAFGYWASACVGNVTYWVLIMSTLGAVAPAFGDGDTLLAVLCSTAGIWLFFYLVQRGVKDAAVLNRVVTIAKVVPILVFVLLALFALDPAVFAGNLRGGVGYGSLFEQVKGTMLVTVFVFLGVEGASVYSRHAKRRQDVGRATILGFLSVFAVFASVTIVSYGILPAAEIAQLRQPSMGGVLEAAVGPWGKAFVSVGLVVSVLGAYLAWTLMAAEVLYVAAKDDDMPRFLGRTRRGDVPFPALLLTSILVQVVLIITYFSEDAFNFALDLTSALSLIPFLLAAGYALRIADKAGEKVVATLAVLYTIFLLFAAGPKFILVSFIVYAPATLLFVKARREQGRQLFSGRELVILAVSVIGAVAGITALAAGWISI
>AP019371.1|BBH67593.1|4647926_4649162_-|arginine-deiminase
MSTNFGVYSEVGRLRKVLVCSPGLAHRRLTPTNSDDLLFDDVMWVENAQRDHLDFVNKLRGRGVEVVELHDLLAETVAIPEAKAWLLDRKIVANEVGLGLVEDTRAFLDELKPRELAEFLIGGLATSDLPADFRPGYVALAREATGVREYLMPPLPNTLYTRDTTCWLYGGVTLNPLYWPARHDETLLMKAIYQFHPDFSGATVWWGDPEQDWGLATFEGGDVMPVGNGVVLVGMSERTSRQAITQVAQSLFAAGAAERVVVAGMPKLRAAMHLDTVFTFADRDIVTLYPNIMDGVHTFSLYPGDRGPEVVDEGDRGFTEVVAESLGLKALRVIETGGDVYASERQQWDSGNNAVAVEPGVVFTYDRNTTTNTLLRRAGVEVITIVGAELGRGRGGGHCMTCPISRDPVDF
>AP019371.1|BBH67592.1|4647232_4647925_-|hypothetical-protein
MSFKYEALVFFLALFALYSPVAALSSYLPYVRGYSHAQQVRLALGLAANAFGFVLIAVWVGEPLLELLGISTAALTATGGIALILASVPLMRGTTAEAVPDPVPVPAAGTFDPALDPVQATPPAPPPNPKNVLFTPLTFPLTVGGTTFAFGVAASADAGDVSGRLWLTLAALAYGIVTGVTLYLSGHVERRISAQAAAMLDRVAGILLTAIAVILLANGFTDLVTARLGL
>AP019371.1|BBH67591.1|4646631_4647216_-|hypothetical-protein
MAAVIITTQDWDAGAGKQPRHEGVEFSGLDLCETDLAGIEFDGCTFRDARFNCSQQADVAYLNCTFVNCNFFDAVFTNCKTVGSHFERCTFDITTIDGGDWSFTSLLRADLGSATITGVRMREADLTGARIRNGTLRDCDLSGATLTAADLTACDLRGSDLSALNPTETEIRNAVITADQATTIAMALGLQIRD
>AP019371.1|BBH67590.1|4646404_4646623_+|hypothetical-protein
MTASIVPYEDGPLIVRGDFELRTPDGAPIDPGRGTVALCRCGRSAIKPFCDGTHKAARFKAGTGRDAPAPRT
>AP019371.1|BBH67589.1|4645357_4646329_-|hypothetical-protein
MRLPSARGPVSAALIAYLTGESTTIAIDADPDDDDDLHLTLFTCYELAYRGWDGVDDAFEWDPEVLRLRAVAEKRFEAQLHDLVGAPGPADPATVPAVLRELADADGGPSLSGYLRGRATYDQFREFVTQRSVYHLREADPHTWAIPRLGGDAKAALIEIQLDEYGGGQTPKMHQELFKQTMRWFDLDTTYGAYVDVAGTRTLANNNLMSFFGLHRRNRGMIIGHLAAYEMTSTQPNRAYGNGLRRLGGDPVATAFYDEHVEADAVHEQIAAHDMAGAFARAEPERAGDVLFGARCALALDALWAEDLLARWDLRTGRMALAA
>AP019371.1|BBH67588.1|4644419_4645361_-|hypothetical-protein
MSALLQLAKELHAAGYRFTTVTPATHERVNRRPENAHARDLRGVFGWSRPFGPGVLPPLIVELMDAAGVLDRDEDGWRSRVRFSTYDGELFVHSAFPTDAEDSVFFGPDTYRMANAAATAAERGRDHLRRAVDIGCGTGAGAIAVAKRAPDAEVFAVDINDRALRYTALNAELAGAGNVRPVRSDLLSGVDGDFDLILTNPPFMIDPAGRAYRDGGEHGYELSLRIIDQAVRRLTPGGELVLFTGTGIVDGRDPFQEAAAERLAGSGLTVEYRELDPDVYGEELDGPAYAHAERIAVVLLTARAQRPAVILEQ
>AP019371.1|BBH67587.1|4642730_4644389_-|DEAD-box-ATP-dependent-RNA-helicase-CshA
MTVSGFADLQLRPELLRALTDLGYEEPTPIQAESIPPLLEGRDLLGQAATGTGKTAAFALPVLQRLAGRDDADTPAALVLVPTRELAMQVSQAFHRYARDLGARVVPIYGGQPIGRQLQALERGVDVVVATPGRALDHISRGTLDLSGVRTVVLDEADEMLDMGFAEDIEAILVETPEERQTVLFSATMPGRIDAIARRHLREPVRIQMGRAEPEPGEAPLVRQSAYVVARAHKPAALGRVLDVEAPTAAIVFCRTREEVDQLTETLNGRGQRAEALHGGMSQEHRDRVVNRLRDGRADLLVATDVAARGLDIDRLSHVVNYNLPAAPETYVHRIGRVGRAGREGTAITLAEPREHRMLKAVERTTGQRIALQKVPTVADLRARKLELTRAALQESLLTDDLERFRVVVETLTDEFDVMEVALAAVKLAHEMNGGDLDDEQDIPEFTLRPDRDRKDANSRPGARKGVNTTRVFINSGRSNRIRPQDLVGAITGETRLSGRDIGAIEIADRFSLVEVPADAADEVITALRHASIRGRKVLARRDRDKDNSRRP
>AP019371.1|BBH67597.1|4654813_4656022_-|D-mannonate-dehydratase-CC2812
MRIVDARVIVTCPGRNFVTLKIVTDEGVHGVGDATLNGRELAVAAYLTEHVVPTLIGRDASRIEDTWQFLYKGAYWRRGPVTMTAIAAVDTALWDIKGKAAGLPVYQLLGGRSREGVTVYGHANAEDVESVLSEISGYVGLGYRAVRVQTGIPGLESTYGVGGDKMFYEPADAALPTENVWSTEHYLDHVPKVFAEVRNEFGPHLRLLHDVHHRLTPLEAARLGKSLEPYALTWMEDPVPAELQEGFRLIRQHTTTPIAVGEVFNSIWDCQELITAQLIDYIRATVVHAGGITHLRRIFDLAALHHVRSGSHGATDLSPICMAAALHLDIAIPNFGLQEYMRHTRETDAVFPHGYHFADGYLHPSETPGLGVDIDEELAADYPYRPASLPVNRLHDGTMHSW
>AP019371.1|BBH67598.1|4656022_4656853_-|spermidine/putrescine-ABC-transporter-permease
MRRSIVASPAAWLVWGAVIIFFIGLAGVIGSVVVNSFGVRWFDSWLPEAWTTQWYGQAWDEFTLLPVLTVTLIVCLLVAGISVLVGVPAAYVLARRAFPGSRLLYLLFLLPILMPPITYGIPLATVLYKYGLAGHLSGVVLANLVPSIPFVILTMTPFIEQIDPAVERAARMCGARTRHVFLRILAPLLIPGILASCILVVVRTVGMFELTFLTAGPDSQTLVVALFYSMSAAGIRAQQSVDAMAVIYCLMMLTLLVVALRFVNPTQLVARVKEDP
>AP019371.1|BBH67599.1|4656849_4657737_-|ABC-transporter-permease
MTTATVAFRHRLAERGVDRQMLLLVPATVFVVALFIYPFAYGIAVSLQPAEGGVLGAYRAFFTDAYQRDTIATTLLIALPAALLNVAASVPVAYRMRGRFRGKRVLTTILVVPITLGTVLTAEGLLNFLGPAGWLNRFLMTSGLTDAPVRLTNNYWGVFLSLVITGFPFAFLLVLSYLSGIDPSLERAAATLGAGWRQRFLRITLPLLAPGLATTFCLTFVLAFSVFPSAILVGDPSGSTRVISIAAYEAAYVRYDYAGASAAAIVMGAVELAVIAVVLGLRGFLYTGSTAGGKG
>AP019371.1|BBH67600.1|4657733_4658780_-|ABC-transporter-ATP-binding-protein
MSGFELLRLDGVTRRFGDADALSDLSLEIRRGEFIALLGPSGCGKSTALNCLAGLLPLTGGSIWRDDTRLDTLPPERRGFGMVFQNYALFPHMSVQKNVSFGLQMHGVARAEARRRTTEAIRLVHLEEHATKLPGQLSGGQQQRVAIARAVVIEPSLVLMDEPLSNLDAKLRLEMRTEIRRLHQSLGLTTVYVTHDQEEALSLSDRLVVLRDGRVQQIGTPEEVHTRPANRHVADFMGYRNLLHGRAFGGAFAFQHSPDVRVKGTPVVRLGDGDPAVAAIRPEDISLDGDLEATVDVVEYQGREFTAEVRTADGLVLHLRTGRRLAVGDPLKVGFPADRLLIFGMETA
>AP019371.1|BBH67601.1|4658776_4659973_-|ABC-transporter-substrate-binding-protein
MKGKIGIAVLALALAACSPPESNSGTTSTDGPVPDKPSKPVTLNVLDVAGNLQLTQGMIDDFVAKNSDVIEKVTYTKATAPELVGKIKAQQDAGRVDIDLVLTGVDGLAGGIDQGLWLPLVSSHADRLTGMAAYLPGAAAMQKLAGDNGVTVTYYPSGPLIEYLPKNVPNPPKTAQELLDYAKANPGAVQYARPSNSGPGRTFLMGLPYLLGDSDPKDPENGWSKTWQFLKDLDAQITLYPSSTSETMKNLANGSAKIILTTTGWDINPRVLGTVPKEAKIGTLDGFHWVTDAHYAVVPKGVSTDKQAAVLSLLQWMLTPEQQAKAYDKGYFYPGPAIKDVPLTMAPQESQQAIFEYGRPEYTDLILNNPLEVPLDAKALVAAFDRWDREVGGAKVKK
>AP019371.1|BBH67602.1|4659975_4660959_-|LacI-family-transcriptional-regulator
MTATIKDVARLAGVSQSSVCRALAKPEQVRPETRERVERAARDLGYYPNRAASGLITGRTHNIGVVLPDLANPFFPSVVKSIQTQARRFDYAVFLSDTDEDPAVETTLIRALAKQVDGFLLCSPRAADEELRTIGEEVQTPVVVLNRRVSPFPSVTADSADGMRQAIGHLHALGHRRVAYVAGPRTSWSNRDRLRGLRSATTAYDMELLEAGNVAPTVDGGAAVADLVAASPATAVIAYNDLVALGLLNRFRVRDIDVPGRISVVGFDDILLSGLVMPPLTTVAIAKEEIGRRGVELLIDLLDDRRPLNKRSPTQLIVRDSTGPARS
>AP019371.1|BBH67603.1|4661089_4662034_-|hypothetical-protein
MTRLWTAAAVVWLPVAVTAATRGWLDELPEKIATHWSGSGPADGWSSADGFWLTMLIIGVLSGLTALAAAAVTSRSTDNPADDVRRTAAGRGLVIGVASVSGGAAGVWVATATATLANPADPRLGWRFGWFVIGMAWGLVAWLIAGRAPVIDVPAEPPVDALDLGPTERAAFSTTLRAPLMFGLMLASTAVVVIVAVLTLPGVWLVAPIPLLLGLVFARIRVTADRRGLRLVAGLAGLTFKHIPLDQIVTAETAEIIPTEWGGWGYRVKPGRSALVLRGGPGLVLNLRDGRRFAVTMDDPRTPAALINGLKTSH
>AP019371.1|BBH67604.1|4662045_4662399_-|GntR-family-transcriptional-regulator
MLFRVDVAAAEPLADQIAAQVRGGIMRGELAAGERLPAARELADVLDVNLHTVLRAYARLRDEDLIELRRGRGAVVRGDADAARLRLAELAREFVREARRQGLGETEMLEIVREARP
>AP019371.1|BBH67605.1|4662489_4663344_+|hypothetical-protein
MGWVAAGADYQVSVDRGKVVARTAQGKRLKALPKALRDHEVVVGLRQLIDWLKRHEASCRTEVERWMIRSLPVPAPVIAQVWADESWRSVLRDLVVVPVGPGGDWDVAAAGLLRDADEEKGLGVVDLDGESTRITAATVAIPHPVLLPDLGDLREFAADLGVEQGTLQLFREVWRFSSADDLRRFSGAHYKELRHVQSRATAAGYRVQGGTSVCRIWESGATVLASVWIGDGDPSYETETGDLVFTNAAGEVLAPEQVPPVAWSEGLRMAAALHAGRVVEEEGK
>AP019371.1|BBH67606.1|4663343_4668065_+|DNA-binding-protein
MSEQLLEAGAILAGAPAGGADDAMTARSYRHPVLDGRTVVRLVGATVGPAEDLTMDFLGFEPAAAPAPVGHARRQALGFPAWALVHDPANGRHALALVKEMEKLARVARSKPGNAKDGYDALAGRLGAAAPAFLPTFWEQAGRAFLGADNQRMAGTCFTEARRAEQVHGLAVDEDRVRDVHLEFAFAGALTAAMLAEYARGVVVRRPATEAYALVRTLALRRVAGGLPPHASMAADLARLAKAAGLDPEQEADAIVPQLLGYPAMGRAHPSVWKAYRKSLVRTGRRDPEVRARLLAIVPEPPGWRTDMTAQWLEIIEASGAAADLIAGSGPGADPATPARWLGRILAGRRSSRTSGERSEALLGLVERMLPRLAAGPAVPLADSLWRVELDVLDLCLSAGVPIEIGDRVRRAGFDVAEWAEDKSPGRRDLAAVAADPQWRPVLREGARHAVRRLRNGDSLTSPALPEQTLRHAFGAAGVREVLVDLVTELAGQAGDGTLRRLDLDLTELAPLWSPHGMALAPDAFRRLAAVDVAAVVTRSLRAGLPEELGWGAYEEAARQVKAIRIGESWPELVVHGADAAYVIAPDGAVTEHQFRFPTGSHPHAPVRWSETACRLVDGDLLVMWRGEEGGVGYWSSRPSDLIAADMLSEPVLWQAPAEPLPVPGGGLTTGARPVHPGDPRGPGASYPLASDGQAFWRCEYVRSPSGPAQWQWREFDPRTGAGGRVSVPAFFSDFSPGAGRLDAIASRLRPVPAVFAGSPLGASPDLLAGWRTVVTDDGTQSGEGADGRRVVLPAGAGGSLVGALMLPGAETPLPITHEGGYRNGSLTIWTADGRHPLAVLSPVNSLLPPLAWWHALRPRDEAGSAALRSLAEPVASALLAVDAGVTKTLEVRDAVTANLETHLPGVTDPVLRARLAEVLARAVRLNRRLTEIAAHLEAEPETAPELAGISDEALTEAWKGLEQTSRSYYMGSTGLRHEIMEQIRVVAAHLAGDAGAPPVPAVASGWASLLGGLGAAAVRAASPVVGDADREALVAFLTTVAGTPLTGEGIPVRVAVVTQKRTGSQQAEIHRDGGQVSVLFPPENYHWRDDQVWDRVAVQGSASGVFTPPPGTTVGAETYPSGRMTTARLERFAELLAARGPAPWRPEAAETLAGQTGMTRAEAILLLAGLPGINDWHDNFLTTEQRTVLGLSAAHAKVGRETLRDLTPAQRVALLDAAMPADPAALWETGPDVAAVAAEWIRIRGRRIAVPETLVTDLARFVERIRPVALLQAIADPRPGDWLSTDGRTEMTHYNHLTTTVAQGTAFSQDHLKAAATTLPWLAYRLSWDDPLRLQLPGALRLVRERLRNPHLLVGWAMFEVKNRPDGMPALVERETHNDWMFLHLAPAKLTGPDDPAILYTDDDTRAALKILLSDWIDAAVATPPQATGDPHDPRVAAPVLVGEVAGRFGLDADAAAYYLQLLALPDPTDRNVQAWNGWKPAQLRRAREALLAAELVVAAKRERAGRPIFLPGGWFPARAPMLPVETWKAEMYQHAVNQRLVTRSLPDQFAMAWSRVTGGDIPRYSTLEEKP

Crispr_ID: AP019371_10

• CRISPR_ID: AP019371_10
• CRISPR_location: 5339002-5339165
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_10

Consensus_repeat	Method
CTCGGTGCTCTGAGCTTCTTGTGCGGATCTTGAGTGATTCTGAACTCTGGGA	CRISPRCasFinder

spacers of AP019371_10

>10.1|5339054|60|AP019371|CRISPRCasFinder
GGTGCAGGATCGCTCAAGATCTGGTGGTGGTGGTGGTGGTGGTGGCGGTGGCGGGCTGCT

CRISPR arrays and Neighbor proteins around AP019371_10

CRISPR arrays

The CRISPR arrays of AP019371_10

>merge|AP019371|10|5339002-5339165|CRISPRCasFinder
CTCGGTGCTCTGAGCTTCTTGTGCGGATCTTGAGTGATTCTGAACTCTGGGAGGTGCAGGATCGCTCAAGATCTGGTGGTGGTGGTGGTGGTGGTGGCGGTGGCGGGCTGCTCTCGGTGCTCTGAGCTTCTTGTGCGGATCTTGAGTGATTCTGAACTCCGGGA

>AP019371|10|7|5339002-5339165|CRISPRCasFinder
CTCGGTGCTCTGAGCTTCTTGTGCGGATCTTGAGTGATTCTGAACTCTGGGA	GGTGCAGGATCGCTCAAGATCTGGTGGTGGTGGTGGTGGTGGTGGCGGTGGCGGGCTGCT
CTCGGTGCTCTGAGCTTCTTGTGCGGATCTTGAGTGATTCTGAACTCCGGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH68182.1|5336427_5337654_-|MFS-transporter	unknown	unknown	gnl|CDD|225371
AP019371.1|BBH68189.1|5344707_5347005_+|chaperone-protein-ClpB	unknown	unknown	gnl|CDD|214361
AP019371.1|BBH68175.1|5326078_5326774_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
AP019371.1|BBH68180.1|5330666_5335298_+|hypothetical-protein	unknown	unknown	gnl|CDD|227922
AP019371.1|BBH68192.1|5349963_5352192_+|hypothetical-protein	unknown	unknown	gnl|CDD|366375
AP019371.1|BBH68186.1|5342122_5342956_+|ABC-transporter	unknown	unknown	gnl|CDD|223692
AP019371.1|BBH68191.1|5349584_5349770_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH68185.1|5340158_5341898_+|heme-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213192
AP019371.1|BBH68179.1|5329210_5330461_-|polyamine-binding-lipoprotein	unknown	unknown	gnl|CDD|270308
AP019371.1|BBH68187.1|5342973_5343510_+|hypothetical-protein	unknown	unknown	gnl|CDD|378252
AP019371.1|BBH68193.1|5352165_5352837_-|haloacid-dehalogenase	unknown	unknown	gnl|CDD|223710
AP019371.1|BBH68181.1|5335282_5336350_-|alkene-reductase	unknown	unknown	gnl|CDD|239243
AP019371.1|BBH68174.1|5325169_5325949_+|transport-permease-protein	unknown	unknown	gnl|CDD|366444
AP019371.1|BBH68176.1|5326816_5327419_-|hypothetical-protein	unknown	unknown	gnl|CDD|379312
AP019371.1|BBH68178.1|5327803_5329168_+|hypothetical-protein	unknown	unknown	gnl|CDD|227642
AP019371.1|BBH68177.1|5327433_5327631_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH68184.1|5339292_5339850_-|hypothetical-protein	unknown	unknown	gnl|CDD|379468
AP019371.1|BBH68190.1|5348189_5349266_-|hypothetical-protein	unknown	unknown	gnl|CDD|237019
AP019371.1|BBH68183.1|5337729_5338734_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
AP019371.1|BBH68188.1|5343498_5344488_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH68182.1|5336427_5337654_-|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.61857e-68
AP019371.1|BBH68189.1|5344707_5347005_+|chaperone-protein-ClpB	gnl|CDD|214361	CHL00095, clpC, Clp protease ATP binding subunit.	0
AP019371.1|BBH68175.1|5326078_5326774_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	3.62697e-36
AP019371.1|BBH68180.1|5330666_5335298_+|hypothetical-protein	gnl|CDD|227922	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms].	3.46255e-07
AP019371.1|BBH68192.1|5349963_5352192_+|hypothetical-protein	gnl|CDD|366375	pfam00931, NB-ARC, NB-ARC domain.	1.04962e-12
AP019371.1|BBH68186.1|5342122_5342956_+|ABC-transporter	gnl|CDD|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	6.52956e-22
AP019371.1|BBH68185.1|5340158_5341898_+|heme-ABC-transporter-ATP-binding-protein	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.56092e-78
AP019371.1|BBH68179.1|5329210_5330461_-|polyamine-binding-lipoprotein	gnl|CDD|270308	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.4032e-92
AP019371.1|BBH68187.1|5342973_5343510_+|hypothetical-protein	gnl|CDD|378252	pfam09819, ABC_cobalt, ABC-type cobalt transport system, permease component. Members of this family of prokaryotic proteins include various hypothetical proteins as well as ABC-type cobalt transport systems.	7.49352e-13
AP019371.1|BBH68193.1|5352165_5352837_-|haloacid-dehalogenase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	1.36985e-46
AP019371.1|BBH68181.1|5335282_5336350_-|alkene-reductase	gnl|CDD|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	9.23272e-157
AP019371.1|BBH68174.1|5325169_5325949_+|transport-permease-protein	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.40066e-12
AP019371.1|BBH68176.1|5326816_5327419_-|hypothetical-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.47705e-22
AP019371.1|BBH68178.1|5327803_5329168_+|hypothetical-protein	gnl|CDD|227642	COG5337, CotH, Spore coat assembly protein [Cell envelope biogenesis, outer membrane].	3.2858e-61
AP019371.1|BBH68184.1|5339292_5339850_-|hypothetical-protein	gnl|CDD|379468	pfam14100, PmoA, Methane oxygenase PmoA. This family is a putative methane oxygenase.	8.9235e-11
AP019371.1|BBH68190.1|5348189_5349266_-|hypothetical-protein	gnl|CDD|237019	PRK11907, PRK11907, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase.	0.00599045
AP019371.1|BBH68183.1|5337729_5338734_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.96194e-86

Protein sequences

>AP019371.1|BBH68183.1|5337729_5338734_+|LacI-family-transcriptional-regulator
MQSGERRTTLADVAAEAGVSVALASIVMRGAAGAGAATRERVLEVAQRLGYQPDSRARLLRSGRSRLLGVVFDTRHPFHVDLLTGLYDAAGRVGYEVTLSAVTPRRDERTAIDGLLQDRCEALVLFSPRTRTADLATLAARMPVVAMMRGIRHRDVDVVRTDDARGSELAVDHLVDLGHRRIAHIDGGTMPGSAERRQGYQRAMRRHGLAELIRIVPGGPGEEDGVSAAARLLTDPPSAVAVFNDLSATGLLDVLRGNGHAVPGDISVVGYDDSTFSRLAHIDLTTVAQDVDALAGQAVRRAVARIESTAVDHREVVIEPRLVVRGTSGPPAEP
>AP019371.1|BBH68182.1|5336427_5337654_-|MFS-transporter
MDNLTAGRRWAALLALSLGGFGLGLTEFVAMGLLPEIASDLLPADYARSHADAVATAGWMITIYALGVVIGAPTIAAMTARAARRRLVLSLLGLMVVGTAASALAPTFELVLAGRFVAALAHGAYFGAAGILAANILGPGNQGKGVAMVIGGLTAANLLGVPLITALGQSQGWRAAYLAVAAVFALTLVAVLVTVPAVAAAPGGSPRAELAAFRSPQVWLVAATVAIGTSGFFAVNSYVAPVTTQITGLSSSTVPWVMAVMGLGMTAGIAVGGVAADWNLRRTVLIGFIAMLASVVVFAATAAHPAGLFLGAFLTGAASLFIVPALQALLIAAAPDAQLMGAAVNQSSLNIANSIGAALGGAAIAAGWGYLSSAWLGVALTVIGLLLALLSFRHKAPAPTDNREPVTV
>AP019371.1|BBH68181.1|5335282_5336350_-|alkene-reductase
MTNKLFTPTTLGALNLRNRLVMAPLTRIRAGEDGVPGDLLVEHYRQRASMGMIITEGTWPVREGRTWIGQPGIETAEQVAGWRRVADAVHAEGGTIVMQIMHGGRISHPAISLTGRTVAPSAIAAPGEIRIPDGKTPLPVPDALTEQEIAGIVAGFVAAARNAIEAGLDGVEIHGANGYLIHQFLAPNANSRDDSYGGTPAGRARLAIEVVTAVSEAIGPERTGIRVSPEHNIQGALETDPDDLAATYAALADGLAPLGLAFVDVLHHEPAGVLTQSFRKVAPVIANTGFGTQTTRDEAIALIEQNVAEAAAVGRAAIANPDLAARWQHDTEENAADPSTFYTPGPRGYTDYPAR
>AP019371.1|BBH68180.1|5330666_5335298_+|hypothetical-protein
MGRAGWALIAVALLAPGLWVIVQAFGAPEKEFERWVGWANIIALFVGGLGASLVVVEKLTGKPHTPIDDEALDRAAGELAARLTGDWSREASFRQVNRPAPVIVRWSSTGRPAANRGIVLDDTTGAGWREMPLRGDVRQIVDAYRGLPHRQLMVLGGPGAGKSVLAILLLLGLLRAPEENEPVPVLLPLNVWDPAEHLDDFVVRRLAEDYGDVLQAHGDPDRVARLLVEQRRVMPILDGLDELPAARHAAGVEALDGYAAEWRPVVVTCRGEEYVQAVVAGQKVLSRAAVIEIEPVTPSAAAEFLRYPEPGKPRWEPVFEHLDGHPDGALASVLSTPLMVGLARTAYQDPRSDPAELLTLPDAGALADRLMDAYVTGVYAEEPRPAERRRTWSPRPGKARRWLSTLAHHLHTTGNRDLHWWQIDPGVLSRYPRAARVLSRWLPVLLAALVAGALTWPRSGPRMAVFDATIAALVVAAGVSGMIRPLWPDALPPVVLLRYVPDRVRGIRSRQIRLTFGAAGGLLAGALARPAGTSPVIALVVGLAGGLLCGMLAGVRLPWPARTGVRTRPRSSLRQNWAVCGGVAVRHALTAAVLVGALSWPVYGGPGAVTMAAAAAAVFGITTGLAAGGWAWVRFRITHARLVVRGLFPVRLWLFLDDGHRRGALRQAGAVYQFRHVLLQEHLADRVVRVGGSAAHADAVARLPAGLLADEAVAAKVADVLAEQGRFDLLREFYRSAKSGLVGPLAIALVRLGRAEEIPRLLNGFEPAVVIRALVDEGCPELAVPLLDELPGYDMPVAVDVVVALFRAGAAETAIEVARAHGLAGRSRVLEQAVRHGRFDLLLTEFDAGTEAAAVIAERPRLTGGDVLLPGLIARFDRLGPSLRAAVLLASGLEGNADWEKLPPDTIAEALGEHRRIPDLQRRAADGDRHARQSLSIQLGHEGAVQRLRDLAGIGSWTAAARLAEWLGRRRRVDDLRRYADGAIEVVTEARRAVHAAEIYSDAQLRALRDGERREEIWVGALVSTLLAEGRHEDLAELAGHSTIEAIEALAQHHVEHGDLEAGLPWLGELFGIGHPYGAWLPRALVRLGRLDEASGVLRGRTSSTEAEAVEEVVEALLAADRLDDAIELLRSRTSLMDRYTANRHSMLLLAQLFARHGRFAELSDRAEASEDSAVATLLVDTLRSAGRIDDLQRRAGSGDWYAVENLAAMLAEQGRIDDAVTLLQSRADAGSEGAAVYLIGFLAAHGRTDDAIARLRARERGGDEIAALWAAILRRIPEQVTRLRKLAAEGDDYAAQRLAETLLLGGRDQEALVLLRGRADAGDRYCAGLLAHLLTRMRRIGELRDRADAGDGPAAITLARYLDSEFGDAELRKRAARGDDAAAARLSHTRRHWDGNLPDRSVRDRFTAELVIRGGESKKLLATAFFLDERVADGHGWARWMRVDLAVRQERIGVLRELAAGGDAYAARRLAEQLAERGDFAETGRLLRRRVAAGDEYAGWWLTDILGDAGRITELRAWAEESEDEYAWARLAELDPGSQRAG
>AP019371.1|BBH68179.1|5329210_5330461_-|polyamine-binding-lipoprotein
MFPRNTPDSSLLRGVTQRRLGRRDALRLGGLGALGAALAACGVEGKGTPAASVDTNTIATFWAGKQQNNKVDFANWPLYMDPERPELKKFTEKTGIAVNYQEVIQEMGPWFAKVQPQLSAKQAIGYDLMVITNGVQFGQFRSAGFLAPLDHSRLPNFAANAAKAYTTESFDPGNLFSVPWASGITGIAYDPDKVDRPITKLADLWDPAFKGKVGMMSDLTELANFGMLAAGVNPGDSDEAGWKKGAAKLKQQKEAGIVRQYYEQDYVEALGNGEVWITQAWSGDIFQKNLSDGTNFKFVIPEEGGTIWTDNFAIPITAANPVDALMLIDFFYEVENAASLAEYINYVCPVPAAQEQIRADAAELSGDDKKEMLAVAESSLVFPSEADYEKLHYYVSFNTAEEQRDFTSVFEPIVLG
>AP019371.1|BBH68178.1|5327803_5329168_+|hypothetical-protein
MSGPGNSYTLSRRRFGAALAGVLGLAALGGCAAEATTSSTSGGSSDATIFDSGTVHDIELTFEDSAYDAMIEAYRKDETKDWIETAVSIDGTTYQKAGLRLKGNSSLRGLNGSGNQPGGSSISSDKPEDLPWLIRLDKYVDGQAHQGYTDFVVRSNNTESALNEAVALELLGQAGLATEKSFSTRLSVNGGTEVLRLIVENPGDKWDADNFDGAGLLYKAEANGDYSYRGDDAASYKDVFDQEAGDDDLTPLIAFLKFINESDDATFGSDLGEYLDVDAFAKYLAFQELVQNSDDIDGPGNNSYLRYTSSSKIMTVVNWDLNLAFGGMGGGGGMRGGGQQGDAPATAPSGAPAQGGGGFPGGGGFPGGGGDKEAGRGGFGGRSNILVTRFQANSTYAGKYTAAQADLKAALYTSGAAKTVLDRRAAVLTAQAADLVSADTVTSEASKISAFFTS
>AP019371.1|BBH68177.1|5327433_5327631_-|hypothetical-protein
MLMGPAEVRARLRVSRQRAHQVINREDFPEPYQVLPLGKVWDAAEVERWIRRRRPGLAAYGVASS
>AP019371.1|BBH68176.1|5326816_5327419_-|hypothetical-protein
MDFEEMYRSDTPPPWEIGGPQPALAAVLDAGEPRGPRVLDLGCGTGDLALALARLGFQVTAIDFSAAAIDQARAKASAEGLTITFDVQDATRLDLTGHFDAIFDSGLLHSLVRNGADVDAYLARLPELAAPGATLFVLAAALETEGWGVTESFLRSVFSAPAWVGASVEEIDIAAFQGGAPLTLRGFLLRATIPISYAGS
>AP019371.1|BBH68175.1|5326078_5326774_+|GntR-family-transcriptional-regulator
MSSLLSKHESVYRSIRERILGGTYGPGERLVLSAIARDLDVSPVPVREAMRRLEAENLITFERNVGARVNTLDDEAWEQLVEMLALLDGYAMRRAQCRITPAAIGEAQRLNDALRAHAGGPADQHGEVMALHRLFHRILYAAGDNRYLIESLDSAWDRIDASRVLASRWPAHRLVSSVDEHDQLLRMLRSGDVAGDELERCTRQHSLNAIIAIRGRRTPGQLDRAVLPGLP
>AP019371.1|BBH68174.1|5325169_5325949_+|transport-permease-protein
MTTMRAGWILTQRELAHWVREPWGPIFSVLFSIMLLLVFGFLFGGAITLPGGGDYIDYLLPGMLALSMMFGVESTATAMANDAKKGITDRFRSLPIGSASVAFGRVGADMANSVLELFVLIAGGLLVGWRITSDPASAALAVLLLLLLRFAVLWIGIFLGLTFRGGGATAAVQVLVWPIGFLSTAIVSAETMPAWLGAIAAWNPLSATATAVRELFGNPTGVTGGVLEDGAVWLALGWPLVLTAIFMPLSARAYRRLRA
>AP019371.1|BBH68184.1|5339292_5339850_-|hypothetical-protein
MQAIRTLADDALPPAAWTPPHIDEHPRLRPTSDDSLSELSTTGVTATAAHRLIWTGHDGAPVLDEWRALTAQLTGDDSWVLLFENTLTNVSGAPLTYGSAGTTSGGLRWRGTLSFTGDGPSEVRPVQSPPARVVLVADDANPPHPPVHSPGNGHTIAFRHAAAIAAGPRDTEALATLARTALTDP
>AP019371.1|BBH68185.1|5340158_5341898_+|heme-ABC-transporter-ATP-binding-protein
MLQLTGVSVRHEIDEEWGPARPQNVTAEINAGEVVLLLGPSGCGKSTLTLTVNGLIPQVVDAHMDGTVRVGDHDTRTTPVPRMAAEVAMVFQDPDAQIVTATVLDEVCFGPENLLLPPAEVEARAEDALRRVGLWERRDEEPDRLSGGGRQRLAIACALALRTPVLVLDEPTANLDPSGVEEVFRTLRDITADRDRAVLLVEHNLDAAIDLVDRVIVLDAEGRVVLDGPARETLRENADHLLELGVWLPAATLAALRLREAGIVFGRLPLTPAELAAALDATATLPALLRDPEGGGRDRMAGARDLTTGGRPAIAVRGLSVFRGSTRILDGVDLDIAAGEFVAVVGSNGAGKTTLAQALAGVITTRRGAVTADGLDPVTADPRVFAERVGFVFQNPEHQFVTSRVDDELTYGLRVRGVPAEEAEARAGELLDRLGLRELRTTHPFLISGGQKRRLSVGAALITRPHVLVLDEPTFGQDRERAAELLSLLDGLHADGTTIVVVSHDMTLVAEHATRVLVLDGGRIAGDGTPAEIYADADLLEATGLRPPPLARAARALVNHPEWHGLTRLADLPALETTP
>AP019371.1|BBH68186.1|5342122_5342956_+|ABC-transporter
MTRTGRRIEGGRPTHPTANRGRIDPLLDLRTYNPVVKVLAPIPAMVVSIGSRDLRTPAIFALTAMLMLILFGRLRGRTLLWMIIGPVALVAVMTVSFGVWTDPAKVGDTTALLTIGPFTLWSGALATGLATGLRVASVMLLALLAGLTTDGTDLVRSMITHLRMPYRIGYAGFAAIRFVPRFRQDLEVIRLAHRVRGVVSGQGLLGVGRRYAGYAVPLLAGAIRHGDRVSLAMEARGFGAHRARTERRIVPLRARDAVLAAWLISLCYLVPHISGVG
>AP019371.1|BBH68187.1|5342973_5343510_+|hypothetical-protein
MACAAIGAATGVLLLPANFVAAAISAAVPLVYAAMVGVWLVGPVVALAVLRRPGAAVLTMLIAGIINIPTPAGPSAIITNLMVGVALELGFLVTLYRIWKPWLFYLTAVVFETFYAISAYAFFNIDDMAVAVQGVFFGLMAVSAIVFTGIGLMIAGRLEATGVARGIAPRRRPVLSEG
>AP019371.1|BBH68188.1|5343498_5344488_-|hypothetical-protein
MKESVLLGEITCPSGELVLMDGGSLGLWSGELSPDETAEPGTVAAADFEIAGADALTAARSFDRQSGRYLYDIPQHSVAKVHALFQEHCEEHGFQAALRLFPRRVPHRERLRRALKTGAPDFLVAGVPAVPVGDLPADRPLPVTATPGPDGWREIQIWMGAGTPVETRQLGAIVVEQGRFVFADVDALGDWVHEETLDGLADLVFWGRDEELIAAEFRTDRIGILPGDPFGWANMPDEEAYQLAVRLQHRQFAEPQAEFAFDFRPHSHQWQAMAGIRGSIHDAAVVTAGNADVMVTTTSVGDGAFPVRLDLDVAGKPAAIRIAVTRSAL
>AP019371.1|BBH68189.1|5344707_5347005_+|chaperone-protein-ClpB
MGMFERFTDRARRVVVLAQEEARLLNHNYIGTEHLLLGLAREGEGVAARALEASGITLDRVREQVEEIIGQGQQPASGHIPFTPRAKKILEMSLREALQLGHNYIGTEHILLGLLREGEGVAAQVLVRLESDLNRIRQRVIQLLSGYPEKDVTATGTATAGPPSTSMILDQFGRNLTQAAREGKLDPVIGRESEIERVMQVMSRRLKNNPVLIGEPGVGKTAVVEGLSQAIVSNDVPETLKDKQVYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDEIHTLVGAGAAEGAIDAASILKPVLARGEIQAIGATTNDEYRKSIEKDGALERRFQRVRVEEPSLTHTIEILRGLRDRYEAHHGVSITDPALVAAATLADRYISDRFLPDKAIDLIDEAGARMRIRRMTSAEAGSDVGEEQIAEVLGNWTGIPVYKLTEEESTRLLKMEDELHRRVIGQDDAVRAVARAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALAEFLFGSEDALIQLDMSEFHDRYTVSRLVGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEKAHPDVFNTLLQILEDGRLTDGQGRIVDFKNTVIILTTNLGTRDLVKAVSLGFQASEEAASSYERMKLRVTDELKQNFRPEFLNRIDDTIVFHQLTEDEILHIVDIFVARIEQQLKNKDMGLELSDAARRHLAAKGFDPVHGARPLRRAIQRELEDTLSEQILFNDLRPGQRVVVDVEGDRLTFRAAAAGVPVG
>AP019371.1|BBH68190.1|5348189_5349266_-|hypothetical-protein
MNDTHPRRRNPRPGRARKRAIREQAARTGVPYSVAARVIADLGLQPGESVASHGRTIYPADPLRQSLVEQRERRSFTERLADTRLAASLPAGRPHHLVNRFPPGRGLTGSGVGRLYHGEGRPELLTMLYLAVAAESPALLPDPAGLAWVAEMAEETAVDMECAELDRAARSMLENDTSTLWPRLAASVKSALSSPDPLLRQAATTLTTAQAQPTTITPTRSSPDEAITSTRPSLDAAVTSTRPSPDAAITSTRSSPGAAITHLAAAAALPSPSAPPFDGVRQILDALLMVAEDGHAPGTRVRVLAGPNRGRTATIITAVWGAAGPPIAYRVQLDGATTTLGMAAGELIVLAGQESHPA
>AP019371.1|BBH68191.1|5349584_5349770_-|hypothetical-protein
MRGSEVLGFDPTGRYALACQWNRISQEEAFLRRCDDWAPPRSPPAWPATIRDQAIRSRPLS
>AP019371.1|BBH68192.1|5349963_5352192_+|hypothetical-protein
MSEFGSHLRGLRQAAGLTMEQLAESSGVSARAISDMERGHSRAPQARTLAALAGGLGVDAGELRRVVQAEKASGAGRPRICELPRAVGDFVGRTRERELVRQQAAGEPGRPAPVVVVHGQAGLGKTTLAVRIADEVADEFPDGRFYLDLRGTDPEPLEVGEALLRLLRALEVSPRRIAETDEERSSQLRAVLRDRRCLLVLDNAGSEAQLRPLLPGDSAGLTVVTSRRVLGGLEGVLRIELGALEPAESALLLRGIAEQAALPEAGEAVDAVARLCGHLPLALRIAGTRLATRPSWTASHLQDRLADADRRLAVLEAGDLGVAAAFALSHAQLSPSAKMLFRRLAHVPGVDFSPEIATVLTDETEISDTLEDLVDLGLLQQTGFDRYRFHDLIKLYAGQRLHIEEAAGVRAATRTTMVDWLLRTAIVAGRWFEPAYGRLPDDWDGLVPLSTLEEAGDWLRDETGNWMGALRAAAADGRHQLVVDVAEAMHWYSDRTARHAHWYEVYRLSRTAAAHLPDRHQEVTHLNYLSWAATHCVRRPDEGGDIAMDAYRIATELGDVKEQGWALRYAGDAWRNGGQTERALWAYRTALRLADEIQDHDGYAQLRPGIAMLLNILGRHEEARAECAAALREIDVRPVAPRPALSARTCAHSIAARALVELGEWAEALREAEQALPKAEEFGYAGYLGELRLTMGRARAALGLTEQARPDLAQAVELLSAGSFRADEKLAQEALEALDLRA
>AP019371.1|BBH68193.1|5352165_5352837_-|haloacid-dehalogenase
MPFDAVLFDCDGVLVDSERITNAVLRSMLQDLGWQISEEEGFRRFVGRALTDEVGVIEEHTGFAVTSEWIAEFRRRRDEALAVSLQPIPGAIDAARQIAKLYEGRVAVASGADRRKIELQLTKVGLDDVFAGQIYSGMETAYSKPAPDVYLAAAAGLGIDPARAVVVEDTPTGVRAGVAAGATVLGYCPPDSFAHHEPAVLLRAGATRTFSDMALLGAEIQSL

Crispr_ID: AP019371_11

• CRISPR_ID: AP019371_11
• CRISPR_location: 7065868-7065966
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_11

Consensus_repeat	Method
ACCCTCGCCGTCCCTCACCTCGC	CRISPRCasFinder

spacers of AP019371_11

>11.1|7065891|53|AP019371|CRISPRCasFinder
GGGCCCTCAGCTCGCAGCCCCAACCCTCGCGGGGCCCTTCGCCTCGCAGGCCC

CRISPR arrays and Neighbor proteins around AP019371_11

CRISPR arrays

The CRISPR arrays of AP019371_11

>merge|AP019371|11|7065868-7065966|CRISPRCasFinder
ACCCTCGCCGTCCCTCACCTCGCGGGCCCTCAGCTCGCAGCCCCAACCCTCGCGGGGCCCTTCGCCTCGCAGGCCCACCCTCGCCGTCTCTCACCTCGC

>AP019371|11|8|7065868-7065966|CRISPRCasFinder
ACCCTCGCCGTCCCTCACCTCGC	GGGCCCTCAGCTCGCAGCCCCAACCCTCGCGGGGCCCTTCGCCTCGCAGGCCC
ACCCTCGCCGTCTCTCACCTCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH69828.1|7068429_7069131_-|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|380321
AP019371.1|BBH69817.1|7058363_7058783_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69815.1|7056525_7057464_+|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|235713
AP019371.1|BBH69827.1|7067819_7068452_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69831.1|7070622_7070844_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69823.1|7062945_7064091_+|hypothetical-protein	unknown	unknown	gnl|CDD|225231
AP019371.1|BBH69821.1|7061446_7062559_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69825.1|7066005_7066443_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69833.1|7072047_7072701_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|375435
AP019371.1|BBH69834.1|7072711_7073542_-|short-chain-dehydrogenase/reductase	unknown	unknown	gnl|CDD|180446
AP019371.1|BBH69822.1|7062564_7062786_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69832.1|7071097_7072054_+|esterase	unknown	unknown	gnl|CDD|214473
AP019371.1|BBH69814.1|7055289_7056420_-|hypothetical-protein	unknown	unknown	gnl|CDD|370451
AP019371.1|BBH69820.1|7060752_7061547_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69826.1|7066792_7067110_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH69829.1|7069313_7069781_+|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO	unknown	unknown	gnl|CDD|187753
AP019371.1|BBH69830.1|7069777_7070626_+|hypothetical-protein	unknown	unknown	gnl|CDD|365903
AP019371.1|BBH69818.1|7058942_7060031_+|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
AP019371.1|BBH69816.1|7057480_7058296_-|patatin	unknown	unknown	gnl|CDD|366777
AP019371.1|BBH69819.1|7060018_7060681_+|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH69828.1|7068429_7069131_-|5,6-dimethylbenzimidazole-synthase	gnl|CDD|380321	cd02145, BluB, 5,6-dimethylbenzimidazole synthase. BluB catalyzes the O2-dependent conversion of FMNH2 to 5,6-dimethylbenzimidazole (DMB), a component of vitamin B12; is is a subfamily of the nitroreductase family; nitroreductases typically reduce their substrates by using NAD(P)H as electron donor and often use FMN as a cofactor.	3.58189e-68
AP019371.1|BBH69815.1|7056525_7057464_+|short-chain-dehydrogenase	gnl|CDD|235713	PRK06139, PRK06139, SDR family oxidoreductase.	7.53862e-69
AP019371.1|BBH69832.1|7071097_7072054_+|esterase	gnl|CDD|214473	smart00020, Tryp_SPc, Trypsin-like serine protease. Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.	1.24728e-27
AP019371.1|BBH69834.1|7072711_7073542_-|short-chain-dehydrogenase/reductase	gnl|CDD|180446	PRK06180, PRK06180, short chain dehydrogenase; Provisional.	7.53491e-108
AP019371.1|BBH69823.1|7062945_7064091_+|hypothetical-protein	gnl|CDD|225231	COG2356, EndA, Endonuclease I [DNA replication, recombination, and repair].	1.05227e-55
AP019371.1|BBH69814.1|7055289_7056420_-|hypothetical-protein	gnl|CDD|370451	pfam09362, DUF1996, Domain of unknown function (DUF1996). This family of proteins are functionally uncharacterized.	7.97828e-53
AP019371.1|BBH69829.1|7069313_7069781_+|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO	gnl|CDD|187753	cd09281, UPF0066, Escherichia coli YaeB and related proteins. Uncharacterized protein family UPF0066. This domain includes Escherichia coli YeaB, Archeoglobus fulgidus AF0241, and Agrobacterium tumefaciens VirR. Proteins with this domain are probable S-adenosylmethionine-dependent methyltransferases but they have not been functionally characterized and the substrate is unknown.	1.2724e-45
AP019371.1|BBH69833.1|7072047_7072701_-|TetR-family-transcriptional-regulator	gnl|CDD|375435	pfam17929, TetR_C_34, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in putative TetR family transcriptional regulators found in bacteria.	2.70457e-28
AP019371.1|BBH69830.1|7069777_7070626_+|hypothetical-protein	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.10889e-56
AP019371.1|BBH69818.1|7058942_7060031_+|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.99014e-26
AP019371.1|BBH69816.1|7057480_7058296_-|patatin	gnl|CDD|366777	pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.	1.29096e-14
AP019371.1|BBH69819.1|7060018_7060681_+|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.3379e-70

Protein sequences

>AP019371.1|BBH69823.1|7062945_7064091_+|hypothetical-protein
MPRRVLMVATPALVAVVALLFSMITTPATAAVALTVAQAISSQSGTGTVIGYVVGEPTATSTVRFSGFTGDTAIALADSASETGTGKMLYVQVTSSYRASFGLLSNPSLIGKRISVTGTLTAYFSHAGLKSPTAMSSSSSSSPTVTPTATASTDGYYAAASGKSGSSLKTALHGIISSNVTTISYDAVWNALKVTDQDPANSSNVILLYSGTSRSKTLNGGSSGNWNREHVWAQSHGDFGTGNGPGTDLHHLRPEDVTINSTRGNKDFDNGGSAVSGASGNYTDADSWEPRNAVKGDVARMIFYMAVRYEGGDGFADLEVNNTVSNGSNPYLGKLSTLLAWNTQDPPDAAEKNRNQIIYASYQHNRNPFIDHPEWVSSIFG
>AP019371.1|BBH69822.1|7062564_7062786_-|hypothetical-protein
MRFRLSLLLLVGGLLKPPPGWMMSHFKRQPRPNRWYYQCGACEAVRDFARKPRKTPHCKNDGQFMRLIYRPGG
>AP019371.1|BBH69821.1|7061446_7062559_-|hypothetical-protein
MLGGLVQAGSKALGGDRFSLVGLLPTTLLVGWVAFLTVSGLYRGDRVDLSGIVATVGKSAGWAVFAVFGIFVIAVLLRPLQISLVWMLEGYWDRNPVLKWLEPVAVEWHLRRRHSAEVIANDGVGDPPAGRHLQSVIEDHQRLRAWGIRRARAEERISRYPEDRVAQEIDDPGPLGVEPADEIRLMPTMLGNALRKGEDDAGDRYGLDFPAIAPRLYPHLSDKISKEIARNLDVMETGAALTVVFLLSAACSVPLLWRGDLWAAAVPVALVLALLAYLGTLRTAREHGLLLSAAVDLHRFDMLAKLRYRLPETVDEEWRLNRALSAFLGADSDKAYLIMARYRYAHVPDPTTAVASPVAGDAEGQAAPAG
>AP019371.1|BBH69820.1|7060752_7061547_+|hypothetical-protein
MSFRRLRVAIGVLAVAIGATWAAGGAEALGDATLLLWRALPFAGAGAAVLLLARAAVPRGRLAGPLSLLAGCCAVIVFQLDATIRLPLNLVAPATLIIGGLLLAVGGRFAAESEASPEWIRTSVIWPSHSRLRGRAPVKLVLRSLLGDISVDLTACEYPLGEDDVTVDITMLGGHLHLLLPADWHVRVGRAHLAKGIRGHGSVSRSDPPGADEEIDKLVILNIQGFRGELRLSQPAPPAPPRRRRPAKRQPLSGPGRARSDNAP
>AP019371.1|BBH69819.1|7060018_7060681_+|DNA-binding-response-regulator
MAGVTQPVRVLVVDDDALVRAGLTMMLDGAPGIAVVGEADDGDGVQAAADAHSPDVVLMDLRMPRVDGITATRRLRARPRPPEVIVLTTFDTDENILHALRAGASGFLLKDTPPARIAEAVRQVAAGEPILSPRITRRLMDRVAVQAGAFAQATRVLDALSPRERDVVLAIGRGYNNAEIATELGMTLATVKTHVSRILTKLDLDNRTQIALLAHDAGLI
>AP019371.1|BBH69818.1|7058942_7060031_+|two-component-sensor-histidine-kinase
MLAVSGLLITMTVIGLWSDRSPGPLLALDLVVGVLSWLLTPLVLWRPVAATAVLTVLAAVSPAATPPATIGALQVARRCPTRQAVAVAAAGIAAHAVQGMWRSNGGISYGWWLILIIAGYGALLGWGAWAQAREALIRSLTDRARRAEAEQGRRVAEARMLERRKIAHEMHDVLAHRLSLLATFAGAMEFRPDSSPEQMSKAAGVVRSGVHQALEELREVINLLREDVVSDDDRPQPVLGDVPRLVDESRDAGTDVELSVTVDKPDEAPPAVARTAYRVIQEGLTNARKHAAGQLVRVTLDGGPGAGLSVSVINKLGGGPPGFSGGAGLVGLTERVRLAGGRLDHEAAGGEFRLRASIPWPA
>AP019371.1|BBH69817.1|7058363_7058783_-|hypothetical-protein
MTNDMRTSNPTTHRRTGRAITVAAGAAGALLLWAVNVPWGGLDLTVRQGGAVQEIGPVAVVVTALLAGFAAWGLLAVLERLSARPVPTYRIIASILLVISLAGPLGSAIGLSSTLVLVGMHVTVGAALIIGLPGRRNCR
>AP019371.1|BBH69816.1|7057480_7058296_-|patatin
MTGIAWHLGVLCGLRRAGVPLGDAGTIIGTSAGSVVGTLLAAGVDLEAAVAAQELEVAPRPPSSNGSGGGGSAARVMAAFAVLADPSIPPQQARAQVGALALAAPNQDEAGYLARMEPLIPVADWPADRDLRLVVVDAVDGRDVVLDRASGASLLQAVSASCAVPGLMPPVTIGDRRYIDGGVRVGAGADLAAGADHLVVMAPMAALSRDRILVEMAATGAGKQLLIEPDEAALEEFGPNFMDPSRRSAAVRAGLRQGAALAGEARAVWPA
>AP019371.1|BBH69815.1|7056525_7057464_+|short-chain-dehydrogenase
MITGASSGVGRAVALAYAREGARLILVARSRPQLESVAQACLDAGASDVRVTAADVNDRAAIDGIPDGDVDVWVHTAAVMAYGRFEDVPADVFNQVVETDLIGAANVARTALARFRRQGHGVLIYGGSLLGTVVTPYTSSYVTSKWGLRALVRSLRLETRDAPGIHVCLVSPGAVDTPIYRTAANFAGRYGQPPPPVDSPEKVAAAILRCARRPRAVVTVGITNRIIQLGFVTMPPLYDALVGPLMRIGGLSREEVAPHNGNVFTPVPPPADFEAATRRRKWSRSAVVAATGAAAAGAALAIRAAARFDART
>AP019371.1|BBH69814.1|7055289_7056420_-|hypothetical-protein
MRIHSRAVLAVVTASVLAAGGLYLIIAGSGEGPGAGVPRAQPVAGQAKATTGEATPPATATTSAASPSPSTIQASASASAGASAPARQAARGGWVKVDQALWKKQLAAFKALKPAPVRNNPVKVPEFHVDCTVAKQSPDDAIVFPNLPGASHMHTFFGPDIIGASTTTKDLLAAEKTSCRTKGDNSAYWMPQLTRNGKPVPPHGFRIYYGSRLKDPSRTTILPPGLVMIAGDAKRQEPTPKDSGINQFWCAGAAEVGRSADGNWPKCGTGGRMIISITFPDCWDGKHVDSPDHRSHVGPAGPDGTCAGGRFPVAIPSISELFTYDTRGGDGFALSSGLPSSAHMDMMNGWDPAVLGPLVRTCINQGVKCGTTPTFD
>AP019371.1|BBH69825.1|7066005_7066443_-|hypothetical-protein
MGLAVSEGGDDYWVTLSVGYEVGGRWPDGFDDVLFAVADLLNEDPGWHGWWRRGGYRSFQVLLRYVAAEPGADEFWVDGSVVGAEVVVGGEGIAELDAVDRVERVRRDVGTVIDGVRTWLGLEGAPELPSVTEIVRAAEEAEYDG
>AP019371.1|BBH69826.1|7066792_7067110_+|hypothetical-protein
MVTGPVPPEAMTIEPALPETMAPGPEPPSAMPTEPVLAETMASRVVVRTAGCGGPDPPRAMPTEPVPVETMATEPDPPRAMPTEPTGPLTVTELVAVTELVAATE
>AP019371.1|BBH69827.1|7067819_7068452_+|hypothetical-protein
MAGARAFGRLGRLGESWHIVDWSQTGLSRRHDENDPVRARAGFLAIGPGGVYAVTVADQGLFRVLIVGDVVQISGRRLPYVAEARRAASRAAAAISAAAGVNVPVTPVLAFTGSGALSTHGVPTTCLITTDRDLDKLLVAGGSRINPGTAARLARIARDRAAAQVTALARQATPQAGAKSHDGPTSQAGHNGNKAGQNGKPQVPNPRGRG
>AP019371.1|BBH69828.1|7068429_7069131_-|5,6-dimethylbenzimidazole-synthase
MRCPAADDLGATGPPAPAPPEVSDIYEVIHRRRDVRGQFTGEPIPDDVLARVLAAAHAAPSVGLSQPWDFILIRSAATRAAFHEHVMHERDVFAATLPDSSSFEKIKIEGVRESTLSIVVTYDPDRGSPAVLGRHAIADAGLYSVCLAIQNLWLAATAESLGVGWVSFYRESFVQEMLGIPPSVRPVAWLCLGPVTHLESTPDLERHGWRRRTPWQEAVHSERWPSFTPGRED
>AP019371.1|BBH69829.1|7069313_7069781_+|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO
MVAFEITAVGVVRNGRTDVQHTDNWGAVTSTIVVDERFGDECLLGLDGFSHVEVLFVFDRLDELDDYREPRPYRGRDDLPPMGIFAGRGPRRPNRIGVTTCAIEAVRGRELTVRGLDAVDGTPVIDVKPAMAEFSPARVEQPARVTEMMAGYYQP
>AP019371.1|BBH69830.1|7069777_7070626_+|hypothetical-protein
MTVRTEILAKQGDEVLVDDTSDTRYQIASVSKQFTAAAVLLLAEKGALALDDDLGRWIGGWPPITLHQLLTHTAGIGHWHDYPETDLEAEDAPERLLETFRSRPPLFPPGDGWAYSSPGYVLLAHVVERTAGTPYRGFLADRIFTPLGLTRTFAGNAALDEPDVARGHDADGNEVPSWELDVTGMGAGDLWSTAHDLLTWLDALTTDELLSERSRALMLTERAGGYGYGMFVGEVDGRPCWYHTGHNQGFKALAGRIPAVDRRVVVLSNTERTDPRTVEGLF
>AP019371.1|BBH69831.1|7070622_7070844_-|hypothetical-protein
MADETLIRIRAAAEAYAEAVRQTQRYFDRIDDTTDPSVLIEYADLVRNEEAAQADRLDALTAAGLRAESFDED
>AP019371.1|BBH69832.1|7071097_7072054_+|esterase
MWKALAALLAIPVGALMAAAPAEAIANGESVPDGRYPFAVKLIDNGIPTSDGGSRDSSCSGGLVSPHWVLTAGHCFQDENGDRVDRPVAEESLAAVGRTDLTGEDGHLAEVVEVRQHGSADVALARLDRAITDITPLKLNRKKPAAGQKARLVGYGFTKATSKKTPDRLRTGQFRIGGIEKTEMGLSGVSPKASTSPCERDSGGPYFTEKNGVATVVGVVSRGPSCPHTGPDIATRVDAVAPWILKVIKSDLAAAVKPSAKPSAKPSRTRESPQAAPANAAFTLPPMTLLSIPVIFAATIAIALAARSTRRYRGRRRY
>AP019371.1|BBH69833.1|7072047_7072701_-|TetR-family-transcriptional-regulator
MTSADFQRARSPEQREARRRAILDAAAGLLTEIPLTDVSLRELARRVGLSKTNVVRYFETREAVFFALLNQEFDGWLTELPDRLPESDPLAVADALARSLATRPLLCELWSALGAELERNISADAARAFKLAHAELQSRLAELLTVRAEALPIDAAREFTALLILLVAGLWPFANPSPAVAEAVRDPRLAQSRVDFTARLSRALRVTMTGLLTLGPQ
>AP019371.1|BBH69834.1|7072711_7073542_-|short-chain-dehydrogenase/reductase
MSKVWLITGTSRGLGKQLAATALAAGHRVVATARRPEQLEDLIKTYGDRVRTTALDVTDPAAATAAVAAALTAFGRLDVLVNNAGYADVASIEDMPADEFRAQIDANFFGVVNVTRAALPAMRAQGAGHIIQVSSVGGRVGGPGLGAYQSAKWAVGGFSEVLAKEVAGFGIKVTIAEPGGMRTDWAGTSMAEHPVSDAYRPVIEPVVARLRAADGRQPGDPARIAQVLVDLVEHPQPPVHLLLGADAVAVARAQSEALTASDDTWRAVSESVTYTG

Crispr_ID: AP019371_12

• CRISPR_ID: AP019371_12
• CRISPR_location: 7770715-7770813
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_12

Consensus_repeat	Method
CCCCTCGCTGGCCCTCACCTCGCGG	CRISPRCasFinder

spacers of AP019371_12

>12.1|7770740|49|AP019371|CRISPRCasFinder
CCAACCTCCCAGACCCCTCGCTGGCCTCACCCCACGGCCAACCTCCCAG

CRISPR arrays and Neighbor proteins around AP019371_12

CRISPR arrays

The CRISPR arrays of AP019371_12

>merge|AP019371|12|7770715-7770813|CRISPRCasFinder
CCCCTCGCTGGCCCTCACCTCGCGGCCAACCTCCCAGACCCCTCGCTGGCCTCACCCCACGGCCAACCTCCCAGACCCCTCGCTGGCCTCACCTCGCGG

>AP019371|12|9|7770715-7770813|CRISPRCasFinder
CCCCTCGCTGGCCCTCACCTCGCGG	CCAACCTCCCAGACCCCTCGCTGGCCTCACCCCACGGCCAACCTCCCAG
ACCCCTCGCTGGCCTCACCTCGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH70499.1|7768628_7768859_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH70508.1|7776042_7776327_-|phenylacetate-CoA-oxygenase-subunit-PaaB	unknown	unknown	gnl|CDD|237504
AP019371.1|BBH70503.1|7770875_7772180_-|IS256-family-transposase	unknown	unknown	gnl|CDD|307151
AP019371.1|BBH70504.1|7772625_7773453_+|hydrolase	unknown	unknown	gnl|CDD|223669
AP019371.1|BBH70501.1|7769476_7769758_+|hypothetical-protein	unknown	unknown	gnl|CDD|366659
AP019371.1|BBH70511.1|7779000_7779546_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380061
AP019371.1|BBH70506.1|7774675_7775167_-|phenylacetate-CoA-oxygenase-subunit-PaaJ	unknown	unknown	gnl|CDD|131214
AP019371.1|BBH70512.1|7779715_7781656_+|hypothetical-protein	unknown	unknown	gnl|CDD|188651
AP019371.1|BBH70494.1|7761294_7761561_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH70505.1|7773626_7774649_-|phenylacetic-acid-degradation-protein	unknown	unknown	gnl|CDD|131215
AP019371.1|BBH70493.1|7760132_7761335_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277331
AP019371.1|BBH70496.1|7762743_7763961_+|alanine-phosphoribitol-ligase	unknown	unknown	gnl|CDD|380046
AP019371.1|BBH70502.1|7769810_7770515_+|hypothetical-protein	unknown	unknown	gnl|CDD|274426
AP019371.1|BBH70497.1|7764067_7767547_+|hypothetical-protein	unknown	unknown	gnl|CDD|224055
AP019371.1|BBH70509.1|7776323_7777241_-|phenylacetate-CoA-oxygenase-subunit-PaaA	unknown	unknown	gnl|CDD|184320
AP019371.1|BBH70510.1|7777237_7778902_-|oxidoreductase	unknown	unknown	gnl|CDD|143445
AP019371.1|BBH70498.1|7767565_7768450_-|hypothetical-protein	unknown	unknown	gnl|CDD|273938
AP019371.1|BBH70507.1|7775160_7776033_-|phenylacetate-CoA-oxygenase-subunit-PaaI	unknown	unknown	gnl|CDD|368300
AP019371.1|BBH70500.1|7768855_7769326_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
AP019371.1|BBH70495.1|7762079_7762580_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH70508.1|7776042_7776327_-|phenylacetate-CoA-oxygenase-subunit-PaaB	gnl|CDD|237504	PRK13781, paaB, phenylacetate-CoA oxygenase subunit PaaB; Provisional.	5.43729e-58
AP019371.1|BBH70509.1|7776323_7777241_-|phenylacetate-CoA-oxygenase-subunit-PaaA	gnl|CDD|184320	PRK13778, paaA, phenylacetate-CoA oxygenase subunit PaaA; Provisional.	0
AP019371.1|BBH70503.1|7770875_7772180_-|IS256-family-transposase	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	3.23913e-134
AP019371.1|BBH70504.1|7772625_7773453_+|hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.88177e-22
AP019371.1|BBH70502.1|7769810_7770515_+|hypothetical-protein	gnl|CDD|274426	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein. This protein family is found, so far, only in the Actinobacteria (Streptomyces, Mycobacterium, Corynebacterium, Nocardia, Propionibacterium, etc.) and never more than one to a genome. Members show twilight-level sequence similarity to family of AMP-binding enzymes described by pfam00501.	1.12903e-31
AP019371.1|BBH70506.1|7774675_7775167_-|phenylacetate-CoA-oxygenase-subunit-PaaJ	gnl|CDD|131214	TIGR02159, Putative_12-phenylacetyl-CoA_epoxidase_subunit_D, phenylacetate-CoA oxygenase, PaaJ subunit. Phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA (PA-CoA) as the second catabolic step in phenylacetic acid (PA) degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA. [Energy metabolism, Other].	1.80902e-56
AP019371.1|BBH70512.1|7779715_7781656_+|hypothetical-protein	gnl|CDD|188651	cd09819, An_peroxidase_bacterial_1, Uncharacterized bacterial family of heme peroxidases. Animal heme peroxidases are diverse family of enzymes which are not restricted to metazoans; members are also found in fungi, and plants, and in bacteria - like this family of uncharacterized proteins.	9.40766e-150
AP019371.1|BBH70501.1|7769476_7769758_+|hypothetical-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	2.69283e-06
AP019371.1|BBH70505.1|7773626_7774649_-|phenylacetic-acid-degradation-protein	gnl|CDD|131215	TIGR02160, 12-phenylacetyl-CoA_epoxidase_subunit_E, phenylacetate-CoA oxygenase/reductase, PaaK subunit. Phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA (PA-CoA) as the second catabolic step in phenylacetic acid (PA) degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA. [Energy metabolism, Other].	8.25356e-148
AP019371.1|BBH70493.1|7760132_7761335_+|metallophosphoesterase	gnl|CDD|277331	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain. YkuE is an uncharacterized Bacillus subtilis protein with a C-terminal metallophosphatase domain and an N-terminal twin-arginine (RR) motif. An RR-signal peptide derived from the Bacillus subtilis YkuE protein can direct Tat-dependent secretion of agarase in Streptomyces lividans. This is an indication that YkuE is transported by the Bacillus subtilis Tat (Twin-arginine translocation) pathway machinery. YkuE belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.07848e-69
AP019371.1|BBH70496.1|7762743_7763961_+|alanine-phosphoribitol-ligase	gnl|CDD|380046	pfam17885, Smoa_sbd, Styrene monooxygenase A putative substrate binding domain. This domain is found in the 46 kDa FAD-specific styrene epoxidase (SMOA) protein, comprises a part of the styrene monooxygenase (SMO) two-component flavoprotein monooxygenase enzyme. Structural analysis indicates that SMOA monomer comprises two globular domains spanned by a long alpha-helix. This domain contains a putative substrate binding site.	2.00773e-46
AP019371.1|BBH70497.1|7764067_7767547_+|hypothetical-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.86996e-94
AP019371.1|BBH70511.1|7779000_7779546_+|TetR-family-transcriptional-regulator	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	2.1189e-22
AP019371.1|BBH70510.1|7777237_7778902_-|oxidoreductase	gnl|CDD|143445	cd07127, ALDH_PAD-PaaZ, Phenylacetic acid degradation proteins PaaZ (Escherichia coli) and PaaN (Pseudomonas putida)-like. Phenylacetic acid degradation (PAD) proteins PaaZ (Escherichia coli) and PaaN (Pseudomonas putida) are putative aromatic ring cleavage enzymes of the aerobic PA catabolic pathway. PaaZ mutants were defective for growth with PA as a sole carbon source due to interruption of the putative ring opening system. This CD is limited to bacterial monofunctional enzymes.	0
AP019371.1|BBH70498.1|7767565_7768450_-|hypothetical-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.8859e-61
AP019371.1|BBH70507.1|7775160_7776033_-|phenylacetate-CoA-oxygenase-subunit-PaaI	gnl|CDD|368300	pfam05138, PaaA_PaaC, Phenylacetic acid catabolic protein. This family includes proteins such as PaaA and PaaC that are part of a catabolic pathway of phenylacetic acid. These proteins may form part of a dioxygenase complex.	5.31853e-84
AP019371.1|BBH70500.1|7768855_7769326_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	5.35435e-05
AP019371.1|BBH70495.1|7762079_7762580_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.49514e-18

Protein sequences

>AP019371.1|BBH70502.1|7769810_7770515_+|hypothetical-protein
MTDEILTYYDDATGERFGLTAPELGDWVAATAALLTRECGLRRGSRAGVLLPPHWQTAAVLLGAWAAGIEVSFRGWATAGLAPDHGPALDVTFVERRRVGSWLEEIPPAVHQFVLGLAPSGAPMPDVPFGYRDFPSAARAHRGAPPPRSTAAEGEIATVDGTTFGEYGAVAAEVARARGITAGDRVLIETSAVEDPLIWLMSPLTAGASIVLCANLDPTHLSTRIRAEHVSRLL
>AP019371.1|BBH70501.1|7769476_7769758_+|hypothetical-protein
MSARGMLTVVGTAVGGLIGWGGRTPPADPATLRELFTDMGVTIGPDDAELAEAVRYFQRRTGLEADGEAGPATVHLMARYAAEARESHMMEAA
>AP019371.1|BBH70500.1|7768855_7769326_+|hypothetical-protein
MKRLCLPLVLAAATMPLIAGCGTDASPPEWRAAPASPLPAATTEQPSPDPSPSASASASASASAQPVQSASTPGWPSPAAASAPSAGFLAAVRGRLPEMTLDMRPEEITDLGDQACAGLAAGQRRVAVAKSLAGYGLSTADAAAVVSLARSHLCRS
>AP019371.1|BBH70499.1|7768628_7768859_+|hypothetical-protein
MSPTNTTRTVVERRPFGPTISEPAAALRTALPQLPPRFSTTDEPEPEPAGEPVPEPAVSGRSFLPDLPRVPVPGKR
>AP019371.1|BBH70498.1|7767565_7768450_-|hypothetical-protein
MWRRIVVLMTDLLTRPATNDIPPTHIAPVMMKPPRDPRWKKRVAGGAAVLVLVAGGGSAGAYFMEEHLANTSVATAGATAGTQAAVVTEGTDLAPIVAQVQPSVVTVLVDSARSSSLGSGVVLSSDGLILTNNHVIESDGTVSVRLSTGQTVPATVVAADATHDLALVQATGLSGLTPVTFATDDTVAVGDTVLAFGAPLGLEGTVTSGIVSALDRSLDTGDEQLSGLLQTDAAINQGNSGGALVDMSGHLVGINVAIATSGDSTGSVGLGFAIPADTVTSVVAQLKAQISTTR
>AP019371.1|BBH70497.1|7764067_7767547_+|hypothetical-protein
MRLLRDLWATSRSRTALTALLILVGATGGAIALAVAGPVLVDRSWPLFTVLVVALVAGVLSDVFVGLVVARLTADWAARVRRGLNRVAFGQDLPTLENTPVGELLDRIDSDVYQVGSELRGSGVRLAQSLAVATLSIVTTFFVWWPAAIAMILVSILLFTVMNKPVQRISPLRISEEEAWSDLAAVMEEAIHGQDDVRTSLAAPYVRRLYALRAAEVLRRGRLVWRSSSRITMGAGAITRTLIAFLVVAGAWALQAGGIDAARLTAVWLLALGFGGTLEHVTRMVPELQNALGAWSRVQQLSEVAQEPTEGADPVDGDISIRNLTFRYHQGDESRLPVLRNIDIDFKRGRSYALIGRTGSGKSTLAKVLTRAVDVPRGTVFLGGVDVNDIGVEGLRRWTAIVPQRTEILAGTLAENIALFDQELIPAASRAIEELGLTAWVAGLPDGIDTVLGENGYKLSAGQEQLVAFARILVRDPQVVILDEATARMDPVTEAWVQRATDRLLRGRIGVIVAHRLSSVQRCDEVVVLADGEVLEQGPLQESKRFAELMASSKLAVPAGNIGNVGLDETADWDTAVQVELGQDALAGPLPSVDPPELPTPPEARTMREIVRLATNDKRYGLGAVSLFVLLVLFGLDGAILPLLWADVVDGQGSPVVPALGIAAALLALIPTLYFTGAWFPEWWVRQMLRISLRLVHGQIGPRRVSKHTPAEVVAHGGDTERVVMLADNLIDNGVAVITVVAMTLTSQSLVPAGLFVGTMVLSGLAATLFGPRLERAARRTVAARAAFATSLVSSLSAARTVKLAGATDPVLAHLARLDATRSELQRREIAIQVWARSTPSIASGLLPIAAWYLYLNNQLSPAATLIAVATLGSARWFAWTIASLVSHFPSARVWTRRTVAMTGVTDYTSAIPGVDISAGTAPAPATAPRNPLRELSLHHFSAVHENGALGVRDIDLTVGRGELVLVVGPVGSGKSSLLRALAGIVHHTGELRWNDEPVREPEMFLRPNQVGYVAQLPRVLSGTVADNIQLGHEVDAADAVSVAQLEHDLTASGGGLQLLIGHKGTRLSGGQLQRLALARALAPRTELLIADDVSSALDVTTELELWRALRSHGVTVVGSTSKRAALAQADRVVVLIGGQAEAQGSWRELEREWGHLAG
>AP019371.1|BBH70496.1|7762743_7763961_+|alanine-phosphoribitol-ligase
MRDILIVGAGQAGLQLSLSLKAAGYRVTLMAAKTPGEIRDGWPTSTQAMFDPALETERAYGLNHYDLVAPPIRGLHVMLAAPPGNLALQFTAPLGKPAFSTDQRIKFSRWLTDAEQAGVEVIYQPVSPAYLEALTKQYDLTVVAAGRGDLVELFERDPERSPYEQPQRGLAVAYVHGLAPDPSWPEPHVEFHAIPGLGELFVIPTLTRTGPADILFWEVLPGGPLDVFGEDEDHLQTSLNLIKENLPWFHERCADVRLADDKATLQGRFTPTVRKPIAHLTGGGKALGIGDIVIANDPITGQGANTAAKAAHHYLRAIVEHGDKPFDEEWMTATFESFWQAHGRAVTLWTNGMLQPLPPHAQQILGAASANPAVAARFAHGFEDPNDLLSWFADPAAADAYLRSL
>AP019371.1|BBH70495.1|7762079_7762580_-|hypothetical-protein
MTTIVPIDASHPAFAQLAALFDDYRVHYGRPSSPDPTRAWLRHQLSRGALMAAAAVESTRLCGFITTTTMPASLMLSTAWSIRDLYVSPPHRGRGMAQALVNHVIADAREAGALRVSLQTESENVAALALYTKSGFQPVPGLDLLNLSLNPEAPPATNSGSTPAPS
>AP019371.1|BBH70494.1|7761294_7761561_-|hypothetical-protein
MVTPMAATTAMAAVRAMAATTAVAAVRGHGGGGQGHGGGHGCGSGQGAMAAVTARATVAVTVTVVVGAAAAVAAAATAVAWGRAMSGV
>AP019371.1|BBH70493.1|7760132_7761335_+|metallophosphoesterase
MLALMSVGEAVESEPRRRSPRRAIFGVVVLAVVALLFGVPLVTLVWSGNDWPLGVQLGLTAVFVLVALSFPVLMFRGHGGHSDAASRIADTLLGVVWVLFTWSVIGQILAVALGFTSLGDPLRSRLVTAFVLAVSVVLLAWGHYEAMRVSRVRRVDVTIPRLGPGLDGLRVVLITDTHYGPINRTRWSQGVTRVINSLDADIVAHTGDIADGEVQQRLSMAAPLADVRARFARVYVTGNHEYFSGALGWVSHMTSLGWDALHNRHIVVTRGGDSLIVAGVDDRTAAGSGLPGHHADHAAALAGADPSLPILLLAHQPHQIDGAVAHNVDLQISGHTHGGQMWPFHYLVRLDQPALQGLSRHSARTQLYTSRGTGFWGPPFRIFAPSEITLLTLHAPKPQP
>AP019371.1|BBH70503.1|7770875_7772180_-|IS256-family-transposase
MTVTIDATVDTSAVAKKKDPATTPEGVDAELVGQLVEQARAAGLQLTGEGGLLQQLTKRVIEAALDGEITDHLGYEKHDPAGKDGGNSRNGTRAKTVLTDVGPVEITVPRDRDASFEPQIVKKRQRRLTGVEDMVLSLSAKGLTTGEISAHLAEVYGADVSRQTISTITDKVIDGMAEWQNRPLDRVYPVIFLDAINVKIRDGKVANRPIYVALAVTAEGTRDILGLWAGDGGEGAKFWFSVCTELKNRGVEDVLMAVCDGLTGLPDAINTVWPKTVVQTCVVHLLRNSFKYAGRQHYDAIAKALKPVYTAPTEQAAEQRFLEFAEAWGERYPAIVRLWENAWAEFVPFLAFDAEIRKVVCSTNAIESVNARIRRAVRARGHFPNEQAALKCVYLAVMALDPTGAGRRRWTIRWKPALNAFDLAFEGRLTAGRN
>AP019371.1|BBH70504.1|7772625_7773453_+|hydrolase
MPIYAGADGAPLHYDDTDSGSAEAPLIVLAGGAARHPAYLGDLGGLGASRRLVVPHLRGVGESAAGRAKAGSYWRQASDLEGLRSHLGLERIALAGHSAGTRLATAYAAQFPDRLERLVLITPPATHLVAVAPDAAELIARRTGEPAFDAAVAASRRGPDLSSEDAFNSWHLTCAPLGYAAWTAKEQQHATIGRWSLPAVQAYFSVNPPEDFAERLGKVTTPVRVIAGAEDCLTGLAPVVALADVFPNGDVTVIEDCGHYPWVEKPAAFLKAATD
>AP019371.1|BBH70505.1|7773626_7774649_-|phenylacetic-acid-degradation-protein
MAAIDRLCADAVAVTFEVPSPLADRFSFRPGQSLTVRRGGLDERRTYSICSPAGAAPRIGVREVPGGAISSWIVHELRAGDLVEVAPPAGTFTPDLTGGGRHVLIAAGSGITPVLSIAASLLRDPRTDVVVLYGNRRTDTVMFAEELADLKDAYPDRLQVVHVLSRENREVELFTGRLDGERLRALLPLLVDVSAIDHWWLCGPFGMVTDATAMLGEAGVAPSRIHRELFWVDEAPPSPVRAESAPDGPRSEVTVVLDGRSTTIDVPDGVALLDGAQPARPDLPFACKGGVCGTCRARVVDGEVEMRRNFALEPAEVEAGFVLTCQARALSAKVVVDFDQ
>AP019371.1|BBH70506.1|7774675_7775167_-|phenylacetate-CoA-oxygenase-subunit-PaaJ
MVKAAQVVASVVDPELPMITLAELGVVRDVREEGASVVVTVTPTYSGCPAMDSIRSDIRGSLLRAGFARVDVRTVIAPAWTTDWISETGRRKLAEAGIAPPGPAPRRAAGPVPLALTTRPAAVACPRCGHADTETVTAFGATACRDLRRCPACREPFEHMKEI
>AP019371.1|BBH70507.1|7775160_7776033_-|phenylacetate-CoA-oxygenase-subunit-PaaI
MAFDDAYSALTDHEDDARWAFGTGFSDSLSSVPVDLLADIDISDFSAYCLMLGDDALILSHRLQEWVTRAPELEDELAIANIALDLLGQARLLLTRAGQALDRSEDDLAFGRAPGDFRNVRLAERADADFAELAGRLFLMVTWRLAVFDRLSASRDPMLAAIAAKGVKELTYHRDYAAQWVVRLGDGTPESHRRMSAAMTALLPLTGELFVPHPVESRLVPAGVAVDPAAVRTEFEGVLAQVLSAATLSGPVALGDAAPAGGRDGAHTAELSSILREMRSVAHAVPGGVW
>AP019371.1|BBH70508.1|7776042_7776327_-|phenylacetate-CoA-oxygenase-subunit-PaaB
MNHEWPLFEVFVRAKRGLNHVHVGSLRAADHEMALHHARDLYTRRNEGVSIWVVRSDQVAASDPGEKESFFEPSQDKVYRHPTHYSIPSSVPHI
>AP019371.1|BBH70509.1|7776323_7777241_-|phenylacetate-CoA-oxygenase-subunit-PaaA
MTAFEQAIAKDQRIEPADEMPDGYRKTMIRQIAQHAHSEIIGMQPEGEWITKAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGADRGDLTRRLIEGRQKYSSIFNYPTLSFADVGVIGWLVDGAAICNQVPLCRSSYGPYARAMIRICKEESFHQRQGYELLLTMMGGTPEQRGMVQDAVDRWWWPSLMMFGPPDADSPNTAQSMAWKIKRHTNDELRQRFVDMTVPQAAALGVTLPDPSLKWNPERGHHDFGQPDFDELKRVISGGGALNEQRIARRRQADEDGAWVREAAVAHAAKHAGVKP
>AP019371.1|BBH70510.1|7777237_7778902_-|oxidoreductase
MNPAELYETHRELLARAIEATVARDYWSAFPESPSKSVYGDEAAPAGERAFTALLGKPFPIDVPGAVGTVATERSPYGLELAVSYPRADPHALVAAARAATPGWRAAGPEGRAGVAAEILRRINAAGFEIAHAVQHTTGQAFVMAFQAGGAHAQDRGLEAVACALAATTRLPSRSAWSKPQRGGDPLTLSKTATVVGRGVSVVIGCTTFPTWNSYPGIFASLVTGNPVIVKPHPGAVLPLAITVRIAREVLTEAGLDPHVITLAAEEPGDGIAATLATHPDVRIVDFTGGSEFGDWLEANARQAVVYTEKAGLNTVVLDSTADYRGLLRNLAFSLSLYSGQMCTTPQNILIPRDGIETDAGHRSADEFGADLAAALGKLLGDPARAAGTLGAIVNDGVLARLSEAASLSAIAASTAVQDPHFAEATIRTPLVARLDAADEKTFTREWFGPVSFLITTESTDHSLKIFTETVRAHGALSALVHSTSPAVIEAAREAALDAGVHLSENLTGGVFVNQTAAFSDLHGTGANPAATAALTDDWFVTGRFFTLQSRRHS
>AP019371.1|BBH70511.1|7779000_7779546_+|TetR-family-transcriptional-regulator
MLTAAVRLFNDRGYDATSMFDVAESLGITKSTLYHHVTSKEQLLTMAVDRALDGLFEAAADNDAPSATAKLETLIRRSVLVLAERLAFVTLLLRVHGNTEAEQHALARRREFDRLVTDLVARAQAEGGIRADVDPATAARLIFGMVNSLIEWYRPDRGDPAAIAATISTFAFEGLRHRPNG
>AP019371.1|BBH70512.1|7779715_7781656_+|hypothetical-protein
MARLAHGKPLTEDEVNAARADIVAFSARSEASFALAAPPPFGPFDLLFPGLQDDEANLVEQTPKTPEKLAALGTAMADPDQGDDGPIPAAYTYLGQFIDHDITQEIQKPGSGTMTELLAPGMTPLPLAQVRSALANRRSATLDLDSVYEPPAPRDPENSNLMQIGKVAGTNSTRPPLKRPDGKGDDNDLPREPRNDDFTHDRAALIGDDRNDENTIISQLHLAFLKAHNALVKQGLSFEAARRTLRQHYQWIVVHDFLRERVAEPGIVDDIVKNGNRWFNPYGETFFMPLEFSVAAYRFGHSMVRAGYDFNENFNVAAGRAATLELLFTFTAFSGELRDFETLPENWIIEWERVIGDKAQKARKIDTSLAKVGDLALFNLQTIRGERETPDLAARLAARNLLRGYRLRLPTGQAVAQLLGAQVLAKDDIIAAAGGGDSDQARALTAGGFESRTPLWYYILAEAQHFHRGARLGPVGSTIIAEVLIGLIRRSEDSILKAPGWRPTLPATRPGTYELADLLRLAGVLGGPAAPPKPRTYTVKSGDTLTGIARGQLGDERRWTQIYVLNRKEIRDPNRIFPGQVFVLPPQEPVGPIPRLHIVRRGDTLFGIAKAQLGDGNRWPEIFRLNRDVLDNPDRIIPGQVLVLPS

Crispr_ID: AP019371_14

• CRISPR_ID: AP019371_14
• CRISPR_location: 8642399-8642472
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_14

Consensus_repeat	Method
CACCGCCCCCAAGCGGGCCCTCA	CRISPRCasFinder

spacers of AP019371_14

>14.1|8642422|28|AP019371|CRISPRCasFinder
CCGCACACAACACCAGCCCGCGTGCACC

CRISPR arrays and Neighbor proteins around AP019371_14

CRISPR arrays

The CRISPR arrays of AP019371_14

>merge|AP019371|14|8642399-8642472|CRISPRCasFinder
CACCGCCCCCAAGCGGGCCCTCACCGCACACAACACCAGCCCGCGTGCACCCACCGCCCCCAAACGGGCCCTCA

>AP019371|14|11|8642399-8642472|CRISPRCasFinder
CACCGCCCCCAAGCGGGCCCTCA	CCGCACACAACACCAGCCCGCGTGCACC
CACCGCCCCCAAACGGGCCCTCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH71309.1|8636279_8637596_+|maltokinase	unknown	unknown	gnl|CDD|225820
AP019371.1|BBH71310.1|8637622_8639773_+|1,4-alpha-glucan-branching-enzyme-GlgB	unknown	unknown	gnl|CDD|235445
AP019371.1|BBH71303.1|8629978_8630914_-|hypothetical-protein	unknown	unknown	gnl|CDD|237865
AP019371.1|BBH71322.1|8651792_8653691_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
AP019371.1|BBH71312.1|8640641_8641883_+|IS256-family-transposase	unknown	unknown	gnl|CDD|307151
AP019371.1|BBH71314.1|8643351_8644359_+|hypothetical-protein	unknown	unknown	gnl|CDD|99777
AP019371.1|BBH71307.1|8632550_8634515_+|alpha-1,4-glucan:maltose-1-phosphate-maltosyltransferase	unknown	unknown	gnl|CDD|200482
AP019371.1|BBH71308.1|8634525_8636283_+|trehalose-synthase/amylase-TreS	unknown	unknown	gnl|CDD|274140
AP019371.1|BBH71317.1|8648820_8649063_+|PspC-domain-containing-protein	unknown	unknown	gnl|CDD|377200
AP019371.1|BBH71306.1|8632306_8632570_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71321.1|8650320_8651796_-|oxidoreductase	unknown	unknown	gnl|CDD|224806
AP019371.1|BBH71315.1|8644425_8646831_+|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl|CDD|225094
AP019371.1|BBH71319.1|8649171_8649789_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71305.1|8631563_8632148_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71304.1|8630913_8631420_-|RNA-polymerase-sigma24-factor	unknown	unknown	gnl|CDD|132028
AP019371.1|BBH71313.1|8642576_8643296_-|hypothetical-protein	unknown	unknown	gnl|CDD|223704
AP019371.1|BBH71318.1|8648993_8649233_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71320.1|8649769_8650300_-|hypothetical-protein	unknown	unknown	gnl|CDD|239309
AP019371.1|BBH71316.1|8646853_8648635_-|hypothetical-protein	unknown	unknown	gnl|CDD|270916
AP019371.1|BBH71311.1|8639940_8640477_-|N-acetyltransferase	unknown	unknown	gnl|CDD|224584

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH71309.1|8636279_8637596_+|maltokinase	gnl|CDD|225820	COG3281, Ble, Uncharacterized protein, probably involved in trehalose biosynthesis [Carbohydrate transport and metabolism].	2.45917e-109
AP019371.1|BBH71310.1|8637622_8639773_+|1,4-alpha-glucan-branching-enzyme-GlgB	gnl|CDD|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
AP019371.1|BBH71303.1|8629978_8630914_-|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	2.56058e-05
AP019371.1|BBH71322.1|8651792_8653691_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	3.86638e-13
AP019371.1|BBH71312.1|8640641_8641883_+|IS256-family-transposase	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.48549e-164
AP019371.1|BBH71307.1|8632550_8634515_+|alpha-1,4-glucan:maltose-1-phosphate-maltosyltransferase	gnl|CDD|200482	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins. GlgE is a (1,4)-a-D-glucan:phosphate a-D-maltosyltransferase, involved in a-glucan biosynthesis in bacteria. It is also an anti-tuberculosis drug target. GlgE isoform I from Streptomyces coelicolor has the same catalytic and very similar kinetic properties to GlgE from Mycobacterium tuberculosis. GlgE from Streptomyces coelicolor forms a homodimer with each subunit comprising five domains (A, B, C, N, and S) and 2 inserts. Domain A is a catalytic alpha-amylase-type domain that along with domain N, which has a beta-sandwich fold and forms the core of the dimer interface, binds cyclodextrins. Domain A, B, and the 2 inserts define a well conserved donor pocket that binds maltose. Cyclodextrins competitively inhibit the binding of maltooligosaccharides to the S. coelicolor enzyme, indicating that the hydrophobic patch overlaps with the acceptor binding site. This is not the case in M. tuberculosis GlgE because cyclodextrins do not inhibit this enzyme, despite acceptor length specificity being conserved. Domain C is hypothesized to help stabilize domain A and could be involved in substrate binding. Domain S is a helix bundle that is inserted within the N domain and it plays a role in the dimer interface and interacts directly with domain B. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
AP019371.1|BBH71308.1|8634525_8636283_+|trehalose-synthase/amylase-TreS	gnl|CDD|274140	TIGR02456, Trehalose_synthase, trehalose synthase. Trehalose synthase interconverts maltose and alpha, alpha-trehalose by transglucosylation. This is one of at least three mechanisms for biosynthesis of trehalose, an important and widespread compatible solute. However, it is not driven by phosphate activation of sugars and its physiological role may tend toward trehalose degradation. This view is accentuated by numerous examples of fusion to a probable maltokinase domain. The sequence region described by this model is found both as the whole of a trehalose synthase and as the N-terminal region of a larger fusion protein that includes trehalose synthase activity. Several of these fused trehalose synthases have a domain homologous to proteins with maltokinase activity from Actinoplanes missouriensis and Streptomyces coelicolor (). [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
AP019371.1|BBH71317.1|8648820_8649063_+|PspC-domain-containing-protein	gnl|CDD|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	6.39224e-20
AP019371.1|BBH71314.1|8643351_8644359_+|hypothetical-protein	gnl|CDD|99777	cd06170, LuxR_C_like, C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.	9.02077e-22
AP019371.1|BBH71321.1|8650320_8651796_-|oxidoreductase	gnl|CDD|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	1.52986e-35
AP019371.1|BBH71315.1|8644425_8646831_+|RNA-binding-transcriptional-accessory-protein	gnl|CDD|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
AP019371.1|BBH71304.1|8630913_8631420_-|RNA-polymerase-sigma24-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	4.425e-32
AP019371.1|BBH71313.1|8642576_8643296_-|hypothetical-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	3.408e-65
AP019371.1|BBH71320.1|8649769_8650300_-|hypothetical-protein	gnl|CDD|239309	cd03011, TlpA_like_ScsD_MtbDsbE, TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif. The Salmonella typhimurium ScsD is a thioredoxin-like protein which confers copper tolerance to copper-sensitive mutants of E. coli. MtbDsbE has been characterized as an oxidase in vitro, catalyzing the disulfide bond formation of substrates like hirudin. The reduced form of MtbDsbE is more stable than its oxidized form, consistent with an oxidase function. This is in contrast to the function of DsbE from gram-negative bacteria which is a specific reductase of apocytochrome c.	2.40826e-24
AP019371.1|BBH71316.1|8646853_8648635_-|hypothetical-protein	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.95027e-77
AP019371.1|BBH71311.1|8639940_8640477_-|N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.70583e-36

Protein sequences

>AP019371.1|BBH71312.1|8640641_8641883_+|IS256-family-transposase
MAADPSVNVAELLREHLQSASPDLLRAMVKTFADVLMSAEVDALCGAEYGERSTERTNSRNGYRHRDWDTRAGTVELAIPKLRSGSYFPDWLLQHRRRAEQALVSVVATSYLLGVSTRRVEKLVEQLGIKQLSKSQVSEMARHLDAQVEAFRQRPLDAGPYTFVWVDALVIKVREAGRTINVHALIAVGVNADGGREVLGLDVTSDEDGAGWLAFLRSLTARGLGGVRLVVSDAHRGLVGAVGAALPGASWQRCRTHYLRNLLAKVPKSAQPWVATLVRTVFDQPDTDEVHAQFARVLDSIAEKFPDAAEHLDAARDDLLAFTGFPRELWRQIWSNNPQERLNKEIRRRTDVVGIFPNRAAIIRLVGAVLAEQTDEWVEGRRYMGLDLLRKARLTPITTSQDTEAQQPAEIAA
>AP019371.1|BBH71311.1|8639940_8640477_-|N-acetyltransferase
MLIATERLTLRRFRASDAPRLAEYRSDPDVARYQSWEAPFSLAAAEVAVRNFAASSPDVAGHFQYAAELSATGELAGDVYVRLHDNLKQAEIGFTVAAEHQRKGYGSEAVSGVLDRLFRRQGLHKVTGECDARNVASAALMERLGFRREGLLRQQTFIKGEWTDDLLYGLLSTEWGGD
>AP019371.1|BBH71310.1|8637622_8639773_+|1,4-alpha-glucan-branching-enzyme-GlgB
MIGHTTSKLAADQRAMNSVVAGDTHDPHAILGAHPHGGHTVIRTLRKGAKAVAVLHDGERTEMTAVHPDGIFAAELAGTVLDYRLDVDGTQCDDPYRHLPTLGELDLHLIGEGRHEKLWKVLGAQPRGTGVAFAVWAPGAQGVQVIGDFAGWGPYDGWPMRSLGSSGVWELYVPSAHVGTKYKFKILGRDGVWREHADPLAQHTEVPPATASVVYASEYQWHDEQWMRDRARKSWHQEPISCYEVHLGSWRPGLTYVELADQLVAYVLEMGFTHVELMPVMEHPFGGSWGYQVTGYYAPTSRFGSPDEFRFLVDKLHQAGIGVILDWVPAHFPKDEWALARFDGSPLYEHGDWRRGEQPDWGTYVFDFGRKEVRNFLVANALYWCDEFHADGLRVDAVASMLYLDYSRKDGEWTPNQYGGRENLDAISFLQEMNATVYKNHPGVMTIAEESTAWPGVTRPTHLGGLGFGFKWNMGWMNDTLSYIEKEPIYRQWHHHQMTFATVYAWSENYILPISHDEVVHGKGSLTGKMPGDTWQKLANTRALLGFMWAFTGKQLLFMGAEMGDEREWNESGGLHWDLLEDPQRAGVKSLVSDLNRVYRESPALWTQDTSPAGFRWITSEDSQHNTFSFVRFTPNGDAVACIVNFAAVPHEGYRIGLPRGGRWTEVINTDAEIYGGSGVGNLGEVHAEPLPWHGFDSSAALRVPPLGALWLRYEG
>AP019371.1|BBH71309.1|8636279_8637596_+|maltokinase
MTLPFAEWLPKQRWYAGRSRVLASIKEASATPLGEGLELVLVDVDYTDGSSERYQIMVGWGDGPLPEYSAIATIGTADDGRVGYDALYDPRATRHLLGLVDRSETAGDVTFEKEPGVELPLEAWPRVFDAEQSNTSVVFDEDAILKLFRRVTCGVNPDIELNRVLGRAGNPHVARLLGSLQSADESDSCSLGMVTEYATNSAEGWAMATASARDLFADAEFGADQAGGDFQGESYRLGEAVASVHRTLADELGTGPAPFPLDAFLARLRTAANAVPELQQHVPAITDRFTALTGEQVTVQRVHGDLHLGQVLRTPAAWLLIDFEGEPGQPLDERRMPDSPLRDVAGVLRSYEYAAYQLLVEQDDDDDHLAARAREWVDRNRAAFCDGYAHVAGADPREQSALLSAYELDKAVYEAAYEARHRPGWLRIPLRSISRLVG
>AP019371.1|BBH71308.1|8634525_8636283_+|trehalose-synthase/amylase-TreS
MELTSEHDPVEGSHTEDGVVEHPTSEDFGHARALPADRTWFQRAVFYEVLVRAFYDSGSDGGGDLRGLIERLDYLQWLGVDCLWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVEDFVALLDAAHKRGIRVITDLVMNHTSDSHPWFQASRHDPEGPYGDFYVWNDTSDKYSDARIIFVDTEESNWTFDPVRRQFYWHRFFSHQPDLNYENPAVQEAMLDVLRFWLDLGIDGFRLDAVPYLFEEEGTNCENLPATHAFLKHCRKVIDDEFPGRVLLAEANQWPADVVEYFGDPRSGGDECHMAFHFPLMPRIFMAVRRESRFPISEILAQTPAIPENTQWGIFLRNHDELTLEMVTDEERDYMYSEYAKDPRMKANVGIRRRLAPLLENDRNQIELFTAMLLSLPGSPVLYYGDEIGMGDNIWLGDRDGVRTPMQWTPDRNAGFSTATPGRLYLPVNQDPVYGYQAVNVEAQRDSSTSLLNWTRTMLAVRRRHEAFAVGTFRELGGSNPSVLAYLREYGDDVVLCVNNLSRFPQPIELNLQHWNGYTPVELTGHVNFPRIGQLPYLLTLPGHGFYWFQLCGSEEKQ
>AP019371.1|BBH71307.1|8632550_8634515_+|alpha-1,4-glucan:maltose-1-phosphate-maltosyltransferase
MTGRFPIEDVTPAVSGGRYPSKAVVGELVPVSAVSYREGHHALGVNVVWRGPDGETKPFTRMTPGEPGLDQWHTTIRPDAVGRWTFSVEAFDDPYRTWRNAVVKKLEAGQGLEDLANDIAEGAEIFDLAVKIVPPEDEERVREAAAALRDEQRSLFARVTPGIELEELLWHNPVRLLVTTTRSFAIWVDRERALYSSWYEFFPRSEGAEIGPDATPIKHGTFRTAAERLPAVAAMGFNVVYLPPIHPIGKINRKGRNNTLVARPEDVGSPWAIGSDEGGHDAIHPELGTLDDFRYFRERTEELGMEVALDLALQAAPDHPWVKKYPQFFTTRADGSIAYAENPPKKYQDIYPINWDNDYRTLRDEVYRVVMHWVDNGVKIFRVDNPHTKAVNFWQWLIPKVKESDPDVLFLAEAFTRPAMMNGLGKIGFTQSYTYFTWRTTAWEMREYMEQLLTSVDWMRPNFWPNTPDILHESLQHGGPPMFKIRAVLASMLTPSWGLYSGYELFEHVPRPGAEEYIDNEKFELKPRDWAGAERSGRSLAPYLTRLNKIRDENPALHWLRNLRFHEIDNGALLCFSKRDPDTGNTVLVICSFDSSNVQWGNTTLDMAALGLQWHDRFTVVDQITGATYEWGQNNAVRIDPFVEPAHIFVVQTG
>AP019371.1|BBH71306.1|8632306_8632570_-|hypothetical-protein
MGKRPVMISTVVRGAQEDSATGKPTAVSPMNFSGVEVLKRPIAAASQPTGAPLPQRIQTRPRAAGKHDKFTWAQHQARHSLYAGSAV
>AP019371.1|BBH71305.1|8631563_8632148_-|hypothetical-protein
MAGPSTALSPVIAASTHWLARAYPGGESNTVAHTLAELQARQAITVAAWLRYPTEVDAALVAIAGPGGSALLDWKAGSEPEDEFADGEGWRTWVDEVVVSWAACLLADPMLARRGVDSVIAAMPVVPEPRPRPHARRAGGLPNEFRRLLAPDARDREAGSLLRHPDLLEPIAAMHRDSLLYLLDAEQERAPLTV
>AP019371.1|BBH71304.1|8630913_8631420_-|RNA-polymerase-sigma24-factor
MRDATGFDDFYRDTSARMVRYGYALTGDLAEAQDLVQEAYTRAWRRWATVSAHPAPDAWIRLVLARLATDRRRRLRGWWAAMSRTGPPEPVRPPAEDTVLVTAALRQLPDHLRQALALHYLFDLPVAEIAAETGAPVGTVTSWLSRGRKEMAALLTPHVPASASEGGH
>AP019371.1|BBH71303.1|8629978_8630914_-|hypothetical-protein
MSNELERAYAALDRDASERALLLPAADLRARARRRTAVRTAATLVAVAVLAAGTTIGVRVALAGPDRPDPILPATSPTPSVSPSPVSSPSPSSSPSSPPPPSSAPPSSAPPSSAPPSSPAAPAIPKSIPARAMLNKADGNMDTFNRLDEPRAAPSFCSGADFPSEDQAGVRASGWLLFRSPELGPEYTAEDQIYNTVTVYRGDGASAFMDELAAAVEACPEGEVGDLPARFRDLGPLELGDESLMIERSTAAYNDDGSPAEGRRKTFVAAVRVGDAVTMLESSGYESGPSDPDDVEALAATATVRLAGWRQ
>AP019371.1|BBH71313.1|8642576_8643296_-|hypothetical-protein
MTLAVRAVAATDQGLVRSNNEDAVFVGNRLFVVADGMGGLPAGELASDILVQTLSAVDSTPDTGEPLQDLIAALETANQRIEAAVADDDARDGMGTTVTALLLSGDRLAALNVGDSRCYLLRDGDFQQLTRDDTYVQALVDQGVLTPDDARRHPQRALVTQAVQGGPFRPAGRMIPARVGDRYLLCSDGLSDYVEDAMIAQTLREVADRKECAGTLVQRTLDNGAPDNVTVIVADVVEA
>AP019371.1|BBH71314.1|8643351_8644359_+|hypothetical-protein
MLMMPVTLVGRAAALDDLHNACARVREGREPVSVLVTGDQGTGKSSLVAEFLRTQEPIPVLSGAARVHSPAPYDWLAAVLADRDIRDIGVPGDALAWLKQDPDVPRERYTPDALLRLAVTAVRALVGGRPAVLVVEDLHALDPASLNLIAELASPGAALPALLLVTSRPPEAAVSPDLTSRTMARLAGGHGAVRRHLGALRQAEVGKILEMAYGEPPVPELIAAVWRRTEGNPYRVRELIAVEGADGPEALMTRRPDLTAREREVLGCLAAGMANKQIAAVLGISVRTVTVHVSNLLRKTGAGSRTEAALWAVRNGAVPHRVARDLQTASASSAG
>AP019371.1|BBH71315.1|8644425_8646831_+|RNA-binding-transcriptional-accessory-protein
MTTAIHQRIASELGVREGQVAAAVELLDGGATVPFIARYRKEVTGTLDDAQLRTLEERLGYLRELEDRRAAVLESIRSQGKLDDALEQQILEADTKARLEDIYLPFKPKRRTKAQIAREAGLEPLAEGLLNDPTVDPKAAAAAFVDAEKGVADAQAALDGARSILIERFAEDADLIGDLREQMWTRGRLVAKVRAGKETDGAKFSDYFDFAEPYAKLPSHRILAMLRGEKEDVLELTMEPHPEEDEGYFEGRIAGRNGVTDLGRPGDKWLVDTVRWAWRTRILIHLGADLRVRLREHAEDEAVRVFAANLRDLLLAAPAGTRATMGLDPGFRTGVKVAVVDATGKVVATDTIYPHVPQNKWDESIHRLAALASKHDVELIAIGNGTASRETDKLAAELIKRHPDAKLTKVVVSEAGASVYSASAYASQELPGLDVSLRGAVSIARRLQDPLAELVKIDPKSIGVGQYQHDISEVKLARSLDAVVEDCVNGVGVDINTASAPLLTRVSGITAGLAENIVLHRDQNGRFTNRKQIKNVARLGPKAFEQCAGFLRISDGEDPLDFSSVHPESYPLVRTIAADAGSDVKTLIGNSPLLKGIRPDKFVTDTVGLPTITDILKELEKPGRDPRPAFTTATFAEGVEKIADLSPGMILEGQVTNVAAFGAFVDIGVHQDGLVHVSALSEKFVQDPREVVKSGDVVKVRVLEVDPVRKRISLSMRLQDEPNKQRGPREDRGGAQGGQRGGQGGQRGGQGGGQGGQRGGQQRGGQPRQQGGQRGRQGGGAPAPVNSAMADALRRAGLTRD
>AP019371.1|BBH71316.1|8646853_8648635_-|hypothetical-protein
MVDKTVPGERAAPLRPRDPKNLGDYELVGRLGEGGMGTVYLARTATGVLVAVKMVRADLAHDDEFRRRFRSEVNRARQVPPFCTAEVLDADPDHEHPYLVVEYVDGPTLAEVVEERGPLTSANLHGVAIGVATALTAIHGAGVIHRDLKPRNVLLAPGSPKVIDFGIARAMEATSANTRTDQMVGTVAYMAPERFGAEVDIPITPAADVFAWGSVVAFAGTGRTPFWADSPPATAARILTQPPRLDGLSGPLRDLVAHALEKDPANRPSSRELLDLLVSSGERPAATAAAFADQPDLKAAAVEAQAVTGVTPEPPTTPSLALAIPPGLVGYDENSIITVPITDAPTSVGTAAGPVTPKRRGRRWALPAGLAVLIAAVVAGAVMLALSLRPPDGNDAGTGPGADGVTAGQTLIDDALRSPLFWRATDMPEETASCRFEDALVVHRDIEGTYRCSGPLDKMPADLRAEVGVRLVTKDSCAAIWFRFEGNVGYQLRVCERNVYLGVHRSGKVTVLKTFPIANAPIELGAAPTRIGLSYTGKVFQVSRDGAPLGSASLDDERITGGQLVLGIFTERDAPRKGPYEVAFTDVKIWAAG
>AP019371.1|BBH71317.1|8648820_8649063_+|PspC-domain-containing-protein
MNAVHDSMARQGLVRPQDGRMIAGVCAGLGRRFGLDPWIARLLFVLILFVIPGSQILIYPLLWILMPAEKPAWAPTPTTF
>AP019371.1|BBH71318.1|8648993_8649233_-|hypothetical-protein
METGAGVAEETAARDCAGRGTAGCAAAQPAVPVRRSTTLRAAGFMGSLTASLRCGFRQKVVGVGAQAGFSAGIRIQSSG
>AP019371.1|BBH71319.1|8649171_8649789_+|hypothetical-protein
MPLPAQSRAAVSSATPAPVSTAGEAFYRALRPGPAAMLTRQPKSLAAAFAESTAVVVAEVTAVTEGRLIGDMQTAVVDLDVIRVLHGDLQPGLPDTRVEFGVSFLPEPIAPLVGRMHADVPRGPAVWLLKWQGRPAPDRKPGAPRRDPTADLGLYNIVHYNCAILVDGPDRHVVSAIAQDGDPFGAQAEAESYPDLDTLIRQRTP
>AP019371.1|BBH71320.1|8649769_8650300_-|hypothetical-protein
MRVPRLVSMMLVALVAAAGCSTAKTASPVAGAPAAPAVTTVAVPQALAFTGTTLDGAGFDAASLAGKPALLWFWAPWCATCASEAQSVADLHEEYGDRLGILGVGGLGTLDAMKEFVTEMQVGAVPHISDPAGKIWQRFGIAQQSWYVFVDANGTITHRGYLDDLQLTQKVKEFAA
>AP019371.1|BBH71321.1|8650320_8651796_-|oxidoreductase
MSTAQVPPVTAIGTPRITAGFDEYGRLDLVAHQEVHGGFAALSSGELVGLADRIELRGRGGAGFPFARKVRAVIDSCRRQELPPVIVVNATEGEPPSWKDKAVLTRGPHLILDGAALAAAALDAEEIVIGVADDGVGLSSITAALAERKMPCPTRIVTVPHRFISGEGGALVRGINGEAHIPPGRKVRSSDNGVMGLPTLLSNAETYSQLAIAARIGPWEYNSVGIPEEPGTVMLTVGGSATAPAVVEAPSGTPLMDVLTMCGADIGPGLLVGGYHGKWVSAEQAQTITISRKGFAKVGGTLGAGMLIPIGSKTCPLGEVAQVVQYLAGESAGQCGPCRIGLPDLARAVTLVSLGGNAVENVRQAAGLVKGRGACSHPDGTSRFALSALEVFAEDVRAHTNGEGCGKQVRGILPLPYTAEKGARKLALDWSRCDGHGLCSAVAPEIIRLDHNGFPAFPQTPLPPWLEDGARKAVNVCPALALRLTEPTPAK
>AP019371.1|BBH71322.1|8651792_8653691_-|hypothetical-protein
MARSKNNQRAAAPRVAVDVGSTGTRPASRTAIALLVVCVLAALWAVAMMTKPGRVGYYYFFIYAEYYMGVISLVSLSITIMVGLVATDRLVLSIRQRVLLQSTHRTTGLIAVTALVVHVWTKYAEEHIRLIDIAIPFLLPGNSLYVGLGTISGWIMVLVMWTGIARSKFIGRGKPWMWRGIHSISYLMWPIALMHGLSAGRPAATWVTVSYVVCVLGVLVGLAVRLSVSLNRKKDFSSAAGTGIKPVGQLVPTGAAPKRRGRRGGDATGDLMAPPGPATTAAWVPAAPPVPPPAPPVARPVSPAAPPMMPAAAAPVSPAPAGYQAGYPAELEAPAPRQRRSAEDDDRYDTATRAMSRRDIEDERYRYEDEPAPRSRGGRTQEMYDEGPRRGRRFDDDEPPARSRRDVESTGTRMRRDDLEATGTRMRRDDLETTGTRMRRDDVEATGTRMRRDDVEATGTRMRRDDLETTGTRMRRDEIESTGTRMRRDDLESTGTRMRRYADDEPPARGRRREPEYDEAPRRRQDDYDEVPRQRPARYEEEPRGGRYIEEEPPRRRAARDDGRHSSRSQFVDLADGQWGGEPDDAPALEMASRRTRRAEPMERETRAAGRRGRDDDDDYFSQLRGDVREAN

Crispr_ID: AP019371_15

• CRISPR_ID: AP019371_15
• CRISPR_location: 8707820-8707981
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_15

Consensus_repeat	Method
GTGCACTGACCGCCCTCGAACAGCCACGCGTGCGCTCACCGCCTCAGAATCGC	CRISPRCasFinder

spacers of AP019371_15

>15.1|8707873|56|AP019371|CRISPRCasFinder
GGCGTGTGCGGTGGCCGCCCTCAGGACGGCGGTGAGCGCACACGCGACCGGTGCGT

CRISPR arrays and Neighbor proteins around AP019371_15

CRISPR arrays

The CRISPR arrays of AP019371_15

>merge|AP019371|15|8707820-8707981|CRISPRCasFinder
GTGCGCTGACCGCCCTCGAACAGCCACGCGTGCGCTCACCGCCTCAGAATCGCGGCGTGTGCGGTGGCCGCCCTCAGGACGGCGGTGAGCGCACACGCGACCGGTGCGTGTGCGCTGACCGCCCCGAAACCGCAGCCCGTGCACCCACCCCCCCGGACACGG

>AP019371|15|12|8707820-8707981|CRISPRCasFinder
GTGCGCTGACCGCCCTCGAACAGCCACGCGTGCGCTCACCGCCTCAGAATCGC	GGCGTGTGCGGTGGCCGCCCTCAGGACGGCGGTGAGCGCACACGCGACCGGTGCGT
GTGCGCTGACCGCCCCGAAACCGCAGCCCGTGCACCCACCCCCCCGGACACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH71360.1|8698629_8700240_-|1-pyrroline-5-carboxylate-dehydrogenase	unknown	unknown	gnl|CDD|143441
AP019371.1|BBH71365.1|8704076_8705312_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380569
AP019371.1|BBH71366.1|8705455_8706115_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
AP019371.1|BBH71367.1|8706255_8707473_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71368.1|8708644_8710006_-|pectate-lyase	unknown	unknown	gnl|CDD|214765
AP019371.1|BBH71361.1|8700236_8700968_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213191
AP019371.1|BBH71369.1|8710012_8710348_-|hypothetical-protein	unknown	unknown	gnl|CDD|380393
AP019371.1|BBH71373.1|8714276_8715605_-|dehydrogenase	unknown	unknown	gnl|CDD|223745
AP019371.1|BBH71363.1|8701748_8702720_-|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|119323
AP019371.1|BBH71374.1|8715816_8716842_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
AP019371.1|BBH71358.1|8695792_8697835_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
AP019371.1|BBH71362.1|8700964_8701759_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213186
AP019371.1|BBH71359.1|8697982_8698552_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71377.1|8719120_8719942_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
AP019371.1|BBH71372.1|8712879_8714280_-|uronate-isomerase	unknown	unknown	gnl|CDD|235087
AP019371.1|BBH71376.1|8718140_8719121_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
AP019371.1|BBH71370.1|8710361_8711465_-|oxidoreductase	unknown	unknown	gnl|CDD|223745
AP019371.1|BBH71364.1|8702728_8704006_-|hypothetical-protein	unknown	unknown	gnl|CDD|119324
AP019371.1|BBH71375.1|8716851_8718144_+|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224567
AP019371.1|BBH71371.1|8711461_8712883_-|mannitol-dehydrogenase	unknown	unknown	gnl|CDD|223324

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH71360.1|8698629_8700240_-|1-pyrroline-5-carboxylate-dehydrogenase	gnl|CDD|143441	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), families 4 and 17: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), also known as ALDH4A1 in humans, is a mitochondrial homodimer involved in proline degradation and catalyzes the NAD + -dependent conversion of P5C to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Also included in this CD is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences.	0
AP019371.1|BBH71365.1|8704076_8705312_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|380569	cd06346, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.	3.89674e-58
AP019371.1|BBH71366.1|8705455_8706115_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	7.10877e-47
AP019371.1|BBH71370.1|8710361_8711465_-|oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	8.22429e-22
AP019371.1|BBH71368.1|8708644_8710006_-|pectate-lyase	gnl|CDD|214765	smart00656, Amb_all, Amb_all domain.	3.16004e-54
AP019371.1|BBH71361.1|8700236_8700968_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	1.07251e-101
AP019371.1|BBH71369.1|8710012_8710348_-|hypothetical-protein	gnl|CDD|380393	cd06988, cupin_DddK, Dimethylsulfoniopropionate lyase DddK and related proteins, cupin domain. This family includes mostly bacterial proteins homologous to dimethylsulfoniopropionate lyase DddK from marine bacterium Pelagibacter. DddK cleaves dimethylsulfoniopropionate (DMSP), the organic osmolyte and antioxidant produced in marine environments, and yields acrylate and the climate-active gas dimethyl sulfide (DMS). DddK contains a double-stranded beta-helical motif which utilizes various divalent metal ions as cofactors for catalytic activity; however, nickel, an abundant metal ion in marine environments, confers the highest DMSP lyase activity. Also included in this family is Plu4264, a Photorhabdus luminescens manganese-containing cupin shown to have similar metal binding site to TM1287 decarboxylase, but two very different substrate binding pockets. The Plu4264 binding pocket shows a cavity and substrate entry point more than twice as large as and more hydrophobic than TM1287, suggesting that Plu4264 accepts a substrate that is significantly larger than that of TM1287, a putative oxalate decarboxylase. Thus, the function of Plu4264 could be similar to that of TM1287 but with a larger, less charged substrate. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	4.83467e-09
AP019371.1|BBH71363.1|8701748_8702720_-|branched-chain-amino-acid-ABC-transporter-permease	gnl|CDD|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	3.99632e-61
AP019371.1|BBH71374.1|8715816_8716842_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.0919e-95
AP019371.1|BBH71358.1|8695792_8697835_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	3.42593e-06
AP019371.1|BBH71362.1|8700964_8701759_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	3.51564e-104
AP019371.1|BBH71373.1|8714276_8715605_-|dehydrogenase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.06796e-39
AP019371.1|BBH71377.1|8719120_8719942_+|sugar-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	9.10028e-82
AP019371.1|BBH71372.1|8712879_8714280_-|uronate-isomerase	gnl|CDD|235087	PRK02925, PRK02925, glucuronate isomerase; Reviewed.	0
AP019371.1|BBH71376.1|8718140_8719121_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	6.74538e-80
AP019371.1|BBH71364.1|8702728_8704006_-|hypothetical-protein	gnl|CDD|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	4.3852e-63
AP019371.1|BBH71375.1|8716851_8718144_+|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	7.65118e-38
AP019371.1|BBH71371.1|8711461_8712883_-|mannitol-dehydrogenase	gnl|CDD|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	6.01474e-132

Protein sequences

>AP019371.1|BBH71367.1|8706255_8707473_-|hypothetical-protein
MRRYRSNGGTNARQWKVAGVAVVAVAMVGVGLGVAAAADGAVPTVNCPGVKINVAVPASAQAEITRNLQLLNTQIQEANARIVSTQGQGGANFIQNAILGPLKDKRFATINRMETAIGRTAAKPNLNAEGLSTCGLNANGGASAAQPTAVPTAAAGDNAGGGNTGGGNTGGDNGGNAAAGVPTVNCPAVNIGVAVPAQAKAEVERNLALLNTQIQEANARIVSTQGQGGANFIQNAILGPLEDKRFATINRIETAIGRNAAKPNLNAEGLSPCSLNQNGGNSAAQPTAVATAGPGNAGGDNGGNAAAGVPTVNCPAVNIGVAIPAQAAAEVARNLELLQTQINEANARIVSTQGQGGANFIQNAILGPLQGKRFSAINRIETAIGRNAAKPNLNAEGLSPCTLNE
>AP019371.1|BBH71366.1|8705455_8706115_-|GntR-family-transcriptional-regulator
MVLPKSLQPAPVDGVQFAADKAYQQLRDAILDGDIAPNRRLVEEELAASLEVSRTPVREALLRLAQEGLVARVRGWVVRDHSPQEALQIVEARAAVESAAARLAAEHITAEDLKQLTRIADAIDRPGSTAKELNRLNRQFHGLVTAACGNPLLVQFAQRTNISHWSLSATWLMSAKDAAQVNAEHRQMIDALSRRDGVAVESLVRAHIGRTQLILKQAA
>AP019371.1|BBH71365.1|8704076_8705312_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MTAVSRGLITTLVTGGLVVALTACSSSNSEAPEEAGTTAAAASGPLKVGAILPHTAYAGAGEALVSAVDVAAEDINAAGGVNGSAIELKQVDSTDNNDTAVQAVDSLITSGSNVVIGAYGSGMSGAIVGKITESGAVQISGSNTSSSLTGINPLYFRTAPTDALEAAKLADLVVQDGHASAAIIAQNDAWGQAFQKSMVEAFEAAGVEVVAQQQFNTTDTDYSAQVDAVVAAKPESVVLLSYASYSGSMIESLVGTHGFTDKNLYLSNSTLGKYTIKPSLLKGLRGFLAGPDPAVEADFEKKLLAKNPDLTSFAYAGSTYDAVVVSALAAIAAKSNDGKAIAGKLAEVSGGAEGSTKCTTFKECADLLAAGKAVDYDGLSGGLKFASNNDVTETAYQLYVYDDKGSYAVAP
>AP019371.1|BBH71364.1|8702728_8704006_-|hypothetical-protein
MIPSKAIRWLLAVLALACVIMLPSPASAAPAGEWGFRGLLRDGGKQPVSGAVVEIRDGDQVVGTDTTDEKGRWGVIPVSGPGTYTLTIDTTAAGGHFAGDEYEVEKELVDSPTTLPVLNVVVSTTESSQQVASFTDRLAQRAVSGFNLGLLIAIAAIGLSLVFGTSRFTNFAHGESVTFGGLMGFVFAHVAGLPLLVAAALATILGGVFGWAQDVTLWRPLRRKGVSLITLMIASIGISMAIRSLMQFFFGNASRGMTEESWGTVTIGPVVMPATSYASMGISILVLTAVGLWLKYGRIGTATRAIANNAALAATSGVGVDKVTRIVWVLAGALAALSGVLLGVFNQVSFDMGFNLLLLMFAGVILGGLGTSFGTLAGSIIVGVCTEVLVLWIPADMKYVGGLAVLVIVLLVRPQGIFGRRERIG
>AP019371.1|BBH71363.1|8701748_8702720_-|branched-chain-amino-acid-ABC-transporter-permease
MDIIWNSLRELITPTTAAYALAAIGLNVHFGFTGLLNFGQAGFVAIGAYGFAISVMTFGFSTPLAIAVTLVLAAGYALLLGIPTLRLRADYLAIVTIAAAEIIRFALNSSAFARWTGGANGLYNEYSGWLKDSNPYPEGVLTLGPWTFGSNDLWIATVDWIVVLLTAGAIYLLVGSPWGRVLKGIREDEHAMLSLGKNVNLYKLQALVIGGVIGAAAGILYVQPTSVQPFDFGTRMTFNMYTMLILGGAATVFGPILGSMIFWVVMRFTDELVNIGVEHGLFENVTQGSQLRFFLVGVALVLLVVFRPQGILGNRTELSFDAR
>AP019371.1|BBH71362.1|8700964_8701759_-|ABC-transporter-ATP-binding-protein
MRDDAILIADRVHRHFAGVTAVDVDHVEIPRGKITALIGPNGAGKTTFFNLLTGFDKPQTGEWTFDGTPVAGLPSYKIARLGMVRTFQLTKVLGRLTVLENMLLGSKEQKGERLRPSLWRRREKSDQARALEILERFKLAAKAQDYAASLSGGQRKLLEMARAIMNEPSMVMLDEPMAGVNPALTQSLLEHIKGLKDHGMTVLFVEHDMHMVRYVADHVVVMAEGRIIAEGMPGEVLSSTAVVDAYLGAHHDTDLRQLIREMES
>AP019371.1|BBH71361.1|8700236_8700968_-|ABC-transporter-ATP-binding-protein
MIVEVKGLVGGYLPGINILNGCDLTADSGELVGILGPNGAGKSTLLKAIFGMVRIRGGQVLIAGEDVTGVSAEKLVARGVGFVPQSSNVFTDLTIRENLEIGIFQRPKEFTARLAAVCDLFPDLTARLKQKAGSLSGGQRQTLAMARALMTNPSVLLLDEPSAGLSPQRQDEVFLHAHRIKKSGVAVIMVEQNARRCLQICDRAYVLDQGRNAHTGTGEELMHDPKVIELYLGTLATDVEKEQ
>AP019371.1|BBH71360.1|8698629_8700240_-|1-pyrroline-5-carboxylate-dehydrogenase
MNVPTPINEPVRGYAPGSAERLTLQKRIAELAGETAELTSTIGGTSRMAGGSSVNVVQPHHHAQVLGVTRNATHADASAAVSAAIDAAPAWRELPFEARAAVFLKAADLAAGPWRDTLNAATMLGQSKTAQQAEIDAACELVDFLRFNVHFARGILEQQPISSPGVWNRVDHRPLEGFVYAITPFNFTAIAGNLPSAPALMGNTVIWKPSVTQQLAAHYTMRLFEAAGLPAGVINMVTGDGLAVSDVALTHPDLAGIHFTGSTPTFQKLWSTVGANISTYRSYPRLVGETGGKDFVLAHPSADVDSLVTALVRGAFEFQGQKCSAASRAYIPRSLWEGGVRDGLVAATESLTYGDVSDFSHFGGAVIDSRAFARHAAALSRAAAAPHCTILAGGTCDDSIGYFVRPTVIECDDPSDEVFTTEYFGPILAVHVYDSLDEVVGLVDTASPYALTGAIFAQDRGALEDLGRRLRFTAGNMYYNDKPTGAVVGQQPFGGGRASGTNDKAGSWHNLVRWTSPRTIKETFVPPTSHEYPHMG
>AP019371.1|BBH71359.1|8697982_8698552_+|hypothetical-protein
MGWTLVAAVVVLAALLGGWAISKGRQPGPETTDEVDEELVADAEAIRAAAERAVVAADEARHRAEHAEQASSEAEQRYLAAQWEVRSEPGNHLVQRAALDAYRRGDLNVTQLNTIWEHAGTSGLDPRGVDQAREEYDRALAETAQVRQEAHVAEVAAEVLAEETRIVEHDVRQAREASKPGLDGLLDAD
>AP019371.1|BBH71358.1|8695792_8697835_-|hypothetical-protein
MGLGVKQLNDLIADFWADYAAVVLLGGGLLGVIALIGLFIWAKKSQKPLRPVALAFSMNLALLLNAEGMWVIAVDQLKLPKIFAVLVFAVFEICFLTATSLAAEQYRRTTVYGPDGKILTPGHPGPMLYIAALIAAISGIIVASNAVTGTEKLLRLAVPCVIFLMWWAALTAAGQRVRRGRFAYSPRRMAERWGWLIPDDDPDLVRMASERQVRRMVVNYHRVSGNRWPRAWWKSRLLKDARTAGEPVVADVIQQLARIQRVMDLLVPGGLQVAAPVVPQEDAAALLAQPAPGSRRDDLPEGPGGPGRPVPGPVSPAAPQVQFVQPVVADAPDDLVTEALAEALAAQRGGSVGVPIPRRAAEDVPEGPATVPVAATVVRGPTVPAVSGPVDGYDRPAGYGYDRGPIPPAVNGNGNGAAPIAPVAAENGAAPVSPAPAIPAWAAIGTGARPAVSIVGSPWWRLAVDRLSKQVAEEISVEDLPDMTYPRITELARNLAARNTELGEGVVKAFVNDYIRELNGEYGEVAYPWRDFLPPPATAAPGSGAWQAALEELRTALEEELSQGVPADPYELTELLLPSAPRLDEETIRTFIGDYLLALSGQAGSGSNQPWQHLLPRPQSARSATDEEILGAYGGQLEEYLAANGRITRNRVQSITGIKSRLQADRIKAILEERAGVPIS
>AP019371.1|BBH71368.1|8708644_8710006_-|pectate-lyase
MRSRIVLSATLGLILAATAAAVPASSAAAVLASSAAASASAAAAVPAGARAVLPANDGWAAATSGTTGGAAADDAHVFVVRTRAELAAALAGGTDPTPRIVLISGTIRANTDDAGNALTCADYADPAYSLDAYLAAYDPAVWGTATRPTGPLEEARVRSARNQAARIQLRVGPNTTIYGLPNARLVGANLLVQNVDNVIIRNLRLEDAADCFPAWDPTDGSAGNWNSAYDLITLTGATHVWADHNTLSDGDNVDATQPLYFGRPYQVHDGALDVIRASDYVTVSWNTFQEHDKTMLIGSTNTVGADAGKLRVTIHHNKFANVGQRVPRVRFGQVDVYNNYYYLTDEDDYSYSWGVGVYSAIYAENNFLLRSADISLDDFVYDWGGTAMTEIGTLTRVGTGPIRPVSLLAEYNATHDPDLGTDAGWTPTLRAAPPTPSAAVPATVNAGAGAGRI
>AP019371.1|BBH71369.1|8710012_8710348_-|hypothetical-protein
MRKLAVKELQDHHRGPTFTSVLPGHVVQRGGFRVYAQPQFRTHDEPGRHVHSVPEVFVIIQGSGAIEIEGAEVDEFEAGEAIVFEPGEDHHLISRGPDPLVFTWMHLEPVE
>AP019371.1|BBH71370.1|8710361_8711465_-|oxidoreductase
MTPRVALVGAGGHGLSHRRTLQRLADEGRIAVAGLCDRQPFGPDPSAPLDGVPFFTDHTTLLATVHPDVVVICTPPHTHLPIALDVLAAGADLLLEKPPVTSSGEHRELAAAVESTGRLCQVGFQALGSAALAALIAADLAGPIGVFGAWWRPDTYYTRAPWAGRRLVDGRPVFDGALVNPFAHALMQALVIAGPAYRPALLELEAYRTRDIATDDTTFLRVTGADGRQITVGVTLASAVFLAGEIQVGGAALEYPTDRLRLPGSDLIAVPGRTGLLENLLDHRADPAVPLLAPLRRTALFTAMGEAIVRSAPPLEIAPKWLAPHPSGGGSVLPGIDELVRQVAATGELPSEIGVPWAGRPQLLRLS
>AP019371.1|BBH71371.1|8711461_8712883_-|mannitol-dehydrogenase
MKLGLSSQNALPIASRPLVRPGEVRPGIVHLGLGAFHRAHQAVYTESAVAASGGNWGIVGVAPRSREIVDRLREQDQLYSVLTVGSGERDHVRAVGILAGLAHAAGDPYGVVAAVADPGIRIVSLTVTEKAYQPPADLSAQVTGKAPPVSVPALLARGILARHGAPLTVLCCDNLQGNGPRVRSLVAETLEHAGAELPDTVAFPSTMVDRIVPATSADHRRRAALALGADDAVPVAAEPFTQWVIEDRFPGGRPDWAAAGAILTTDVTPWETLKLRALNAVHSALAYLGALAGRELIADALELPGMTGVLRRFLADEVTPAVTPPPGTTVTGYGATVLTRFANRELGHRTLQVAMDGTQKLPHRLLGTVQDLRDQGGTPCWAGLFLAAWMRFARGYADSGAPLPLDDPMASRIRESLSAVPDTPNGVTSALLGLTEVFPPSLAGDDVLRREVVRWYSSLDRHGAEATIREAGA
>AP019371.1|BBH71372.1|8712879_8714280_-|uronate-isomerase
MTHLFPSDPAQRRIAGELYASVKDLPLISPHGHVDPALLADDTPFPDPARLFVVPDHYVTRMLASQGIPQSRLGVPSIDGSEVEQDGREIWRLLAENWHLFRGTPSRLWTEKVFTDVFGIQRPFNKATADIIYDEISDKLRQEDFRPRALFTRFNIEVLATTESPLDELTHHAKLAADGWGDRVITTFRPDNLVDVEWPGWQDRVAALGELTGTDVGTYPGFVNALRRRRELFIAAGATSSDHGHPTAATLVLDDAEAAVLYRKALGGGADAADAEAFRAHMLVEFARMSLDDGLVMQLHPGSVRNHDRSLYERHGRDVGGDIPSATDYVRGLRPLLDAYGNDPRLRIVLYTLDETTFTRELAPLAGGYPALYLGAPWWFLDSPEGLRRFREAVTETAGFYNTAGFADDTRAFCSIPARHDVARRIDAGFLARLVAEDRLPLDEAAETIADLAYHLPKRVFRLDRK
>AP019371.1|BBH71373.1|8714276_8715605_-|dehydrogenase
MPQSPRRRYALVGAGARAGLFLRALATDHADVAELVALADTNPARPAVHNERLRRLGASPVPVYDAADFTGMLKRERVDVALVTTVDRYHADYIVAAIEAGCDAITEKPMTVDAPGCRRILEAVKRTGRTVQVTFNYRYNPLHEAVKRIIQSGEIGEIGSVHFEWLLDVRHGADYFRRWHRDKANSGGLLVHKASHHFDLVNWWLDDEPAEVFAAGRLFFYGDQGRKHGYARDYERAHLADKAEGDPFALKLEDEPGLKELYLDTEHHDGYHRDQNVFAPGVSIEDDMAVLVRYAGGASMSYHLTAYAPWEGYRLMINGSRGRLELEVVESDHVAPAAAGAVKGEPGAESAAESGFKRLLVRPYWAPPREVVVEGLSRGGHGGADVRMLADLVGGSEDPLARMATATDGARALLTGLAANESIRTGTAVRVKDVLNIEEIIR
>AP019371.1|BBH71374.1|8715816_8716842_+|LacI-family-transcriptional-regulator
MAVTIRDVARASGVHISTVSRTFSAPHLVNPETRSRVLATAEQLGYRPNRAARALITGRTHNIGLIVADIANPFFPPLIKAAETHARRRDYHVFVADTDEDPIVEADLVQALAKQVDGILLCSPRMTDDQIEQLRREVPLVVINRMITGLPAVVMDVGQGARSAVRHLLDLGHRHLVYLSGPRGSWTNREIRRAAGATARAAGAELTVLGPHQPVTAAGAAAAEAVLATGATAVLAYNDLMAIGLLQALQDRHIAVPGEVSVVGIDDIAASELVRPQLTTVANPTAAAGRAAVDMLLQQGDDGSTGQINLHTDLVIRNSTGPGPFQPAGATTAEVAAYVKE
>AP019371.1|BBH71375.1|8716851_8718144_+|sugar-ABC-transporter-substrate-binding-protein
MTATHPPRRAFLRTLVAGMLALPLVLGACGSDDAGDDGKTELSFFWWGGEARADLTTKALDLYTAKHPDVTFKKTWQANQGYFDKLATLTAGDDAPDIFQIDDNYLSEYATRNVTLDLTPYQSSGKIDTSKFPEGLWKYGVVDGKLAGLAFGENTQGLVYNKSKLEAAKQPLPTTGMSWEEHIAWAQKAGPAAQTAGTQDPSADYKAFWLWLRQQGKEMYNGNQLGFTAADVTQWFELWKGARDSKATPTADVIHEGNATDITKQLVVTNKALTSWVWANQMPELQKNTTDELGVVAYPGDNSKQWPRASMYFSVFRGSEHADIAADVINFLANDPEAGAILGTDRGLPSNLDIRKSVAASTDNPSMKQTIAVIDELSKSYGPSPTVPPRGHSVVRQELIKAAEEAQYGRATPAQAAEQFFAASQAAVSR
>AP019371.1|BBH71376.1|8718140_8719121_+|sugar-ABC-transporter-permease
MSPVAVTQAPSPAPTAGPAATRRRGRPARHKSDGAAGYIFLSPWLLGFAAITAVPMLMSLYLSFTNYDVLSDWSSTEWVGLDNYRQMFTEDPSFWHAVRVTITFALIATPLKLAAALGVALLLNKAFRGDGVFRGLFYLPSLLGGSVAVAIVWKSMFNGDGSFNAFLAWFGIEGKAWVNDPDYALGTLILLAVWQFGAPMVIFLAGLKQVPQELYEAASVDGAGPVRQFLAVTLPILSPVIFFNLVLETINGFQGFTSAFVLSGGTGGPVDSTLMYTLHLYNKGFTEYQMGYASAMAWVFLLSIGLITVVIFRTGKFWVHYSDSED
>AP019371.1|BBH71377.1|8719120_8719942_+|sugar-ABC-transporter-permease
MKRSVVLVVLTAIVLYPLVWMLGSSFKSPQEVLNNMSVFPREFTPGNYTDGWSHFDVAFGRFFLNSAMVAILTVVANCVSCLLAAYAFARLRFRLRGFWFAIMIGTLLLPGHVLIVPQFVMFKAFGLVGGDWPYAPLIVPQLLATEAFFVFLMVQFMRGVPRELDDAAKIDGCTAFGVFRHVILPLSRPALVSTAIFSFIWTWNDFFRQLVYLSDLEKYTAPVALTLFIDSSGQSAVGPMFAMSVLSLAPVFLFFVAFQRMLVEGINTTGLKG

Crispr_ID: AP019371_16

• CRISPR_ID: AP019371_16
• CRISPR_location: 8829719-8829807
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_16

Consensus_repeat	Method
CCGGACGGCAATGAGTCACAGCCGAC	CRISPRCasFinder

spacers of AP019371_16

>16.1|8829745|37|AP019371|CRISPRCasFinder
CGAGTCCGGCTGTGCCTGGTTGCTGTGCCCGGAGCCG

CRISPR arrays and Neighbor proteins around AP019371_16

CRISPR arrays

The CRISPR arrays of AP019371_16

>merge|AP019371|16|8829719-8829807|CRISPRCasFinder
CCGGACGGCAATGAGTCACAGCCGACCGAGTCCGGCTGTGCCTGGTTGCTGTGCCCGGAGCCGCCGGACAGCAATGAGTCACAGCCGAC

>AP019371|16|13|8829719-8829807|CRISPRCasFinder
CCGGACGGCAATGAGTCACAGCCGAC	CGAGTCCGGCTGTGCCTGGTTGCTGTGCCCGGAGCCG
CCGGACAGCAATGAGTCACAGCCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH71471.1|8831332_8833852_-|hypothetical-protein	unknown	unknown	gnl|CDD|349463
AP019371.1|BBH71461.1|8821017_8821356_-|L-rhamnose-mutarotase	unknown	unknown	gnl|CDD|377501
AP019371.1|BBH71464.1|8822838_8824182_+|putative-NADH-dehydrogenase	unknown	unknown	gnl|CDD|224172
AP019371.1|BBH71462.1|8821407_8822268_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|227099
AP019371.1|BBH71475.1|8836301_8837417_-|thiolase	unknown	unknown	gnl|CDD|180434
AP019371.1|BBH71460.1|8820587_8820920_-|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71476.1|8837413_8837791_-|hypothetical-protein	unknown	unknown	gnl|CDD|239539
AP019371.1|BBH71463.1|8822278_8822719_+|transcriptional-regulator	unknown	unknown	gnl|CDD|224759
AP019371.1|BBH71465.1|8824233_8824899_+|thymidine-kinase	unknown	unknown	gnl|CDD|235272
AP019371.1|BBH71474.1|8836011_8836305_-|hypothetical-protein	unknown	unknown	gnl|CDD|224462
AP019371.1|BBH71470.1|8830885_8831293_+|hypothetical-protein	unknown	unknown	gnl|CDD|377640
AP019371.1|BBH71459.1|8819830_8820601_+|PaaX-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225864
AP019371.1|BBH71466.1|8824889_8825795_-|hypothetical-protein	unknown	unknown	gnl|CDD|376421
AP019371.1|BBH71469.1|8829892_8830810_-|penicillin-binding-protein	unknown	unknown	gnl|CDD|365903
AP019371.1|BBH71468.1|8827626_8829579_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
AP019371.1|BBH71477.1|8837777_8838236_-|hypothetical-protein	unknown	unknown	gnl|CDD|379194
AP019371.1|BBH71478.1|8838232_8839192_-|hypothetical-protein	unknown	unknown	gnl|CDD|100004
AP019371.1|BBH71467.1|8825860_8827630_+|hypothetical-protein	unknown	unknown	gnl|CDD|224055
AP019371.1|BBH71473.1|8834843_8836007_-|isovaleryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
AP019371.1|BBH71472.1|8833980_8834847_-|CoA-ester-lyase	unknown	unknown	gnl|CDD|225184

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH71471.1|8831332_8833852_-|hypothetical-protein	gnl|CDD|349463	cd06244, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	1.14265e-62
AP019371.1|BBH71461.1|8821017_8821356_-|L-rhamnose-mutarotase	gnl|CDD|377501	pfam05336, rhaM, L-rhamnose mutarotase. This family contains L-rhamnose mutarotase which is a glycosyl hydrolase that converts the monosaccharide L-rhamnopyranose from the alpha to the beta stereoisomer. In Escherichia coli this enzyme is the product of the rhaM gene (also known as yiiL). The tertiary structure has been solved, in complex with L-rhamnose, and the catalytic mechanism determined. His22 is the proton donor. The enzyme naturally exists as a dimer.	6.97831e-39
AP019371.1|BBH71464.1|8822838_8824182_+|putative-NADH-dehydrogenase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.27281e-157
AP019371.1|BBH71462.1|8821407_8822268_+|alpha/beta-hydrolase	gnl|CDD|227099	COG4757, COG4757, Predicted alpha/beta hydrolase [General function prediction only].	1.43608e-51
AP019371.1|BBH71475.1|8836301_8837417_-|thiolase	gnl|CDD|180434	PRK06158, PRK06158, thiolase; Provisional.	5.45212e-143
AP019371.1|BBH71478.1|8838232_8839192_-|hypothetical-protein	gnl|CDD|100004	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	8.36886e-13
AP019371.1|BBH71476.1|8837413_8837791_-|hypothetical-protein	gnl|CDD|239539	cd03455, SAV4209, SAV4209 is a Streptomyces avermitilis protein with a hot dog fold that is similar to those of (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The alpha- and gamma-proteobacterial members of this CD have, in addition to a hot dog fold, an N-terminal extension.	5.19303e-14
AP019371.1|BBH71463.1|8822278_8822719_+|transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	7.43713e-14
AP019371.1|BBH71469.1|8829892_8830810_-|penicillin-binding-protein	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.56474e-31
AP019371.1|BBH71474.1|8836011_8836305_-|hypothetical-protein	gnl|CDD|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	9.70264e-15
AP019371.1|BBH71470.1|8830885_8831293_+|hypothetical-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	5.59076e-08
AP019371.1|BBH71459.1|8819830_8820601_+|PaaX-family-transcriptional-regulator	gnl|CDD|225864	COG3327, PaaX, Phenylacetic acid-responsive transcriptional repressor [Transcription].	9.3043e-36
AP019371.1|BBH71466.1|8824889_8825795_-|hypothetical-protein	gnl|CDD|376421	pfam00932, LTD, Lamin Tail Domain. The lamin-tail domain (LTD), which has an immunoglobulin (Ig) fold, is found in Nuclear Lamins, Chlo1887 from Chloroflexus, and several bacterial proteins where it occurs with membrane associated hydrolases of the metallo-beta-lactamase,synaptojanin, and calcineurin-like phosphoesterase superfamilies.	1.88641e-17
AP019371.1|BBH71465.1|8824233_8824899_+|thymidine-kinase	gnl|CDD|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	4.37402e-65
AP019371.1|BBH71468.1|8827626_8829579_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.29001e-160
AP019371.1|BBH71477.1|8837777_8838236_-|hypothetical-protein	gnl|CDD|379194	pfam13452, MaoC_dehydrat_N, N-terminal half of MaoC dehydratase. It is clear from the structures of bacterial members of MaoC dehydratase, pfam01575, that the full-length functional dehydratase enzyme is made up of two structures that dimerize to form a whole. Divergence of the N- and C- monomers in higher eukaryotes has led to two distinct domains, this one and MaoC_dehydratas. However, in order to function as an enzyme both are required together.	1.06519e-12
AP019371.1|BBH71467.1|8825860_8827630_+|hypothetical-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.35974e-172
AP019371.1|BBH71473.1|8834843_8836007_-|isovaleryl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	2.30862e-147
AP019371.1|BBH71472.1|8833980_8834847_-|CoA-ester-lyase	gnl|CDD|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	1.76836e-55

Protein sequences

>AP019371.1|BBH71468.1|8827626_8829579_+|ABC-transporter-ATP-binding-protein
MSMFGGGFGGPGGGPGSGAIGGMGGTGAGRRGGSPFTGIPPELAAGVAVLESREPDPGEPDPVFSQQPDGGRLTLWSLLSRRPYFLVTAAVAVVVEAMLLQSGPLLVQIGIDHGISAGDRRVLIASAVAFLASVGLTALASGVRIRQSGRLAAYAMRDLRVRIFTHLQRLSLDFYVKEKAGVTMTRMTSDVEALQQLLQEGFAQFLIHGLTMVLVTAVLIHYNATLALITFVLVVPPLLLLSLWFRRAADVGYNRQRDSIASLFSHLSESLYGVRVITAHNQQDRNVIEHRGVVGAYRDANDHTGRINAIYGPGTSVIGLLGLAAILGIGGRMVLGGTLTIGELTAFVLYLNAFFQPVQQLVQLYTNYQQARAALGKLRGLLTTRPSVPEKSSSVPLPPVVGEIMLHDVTFGYFDDRPVLRNVSLRISPGETVACVGPTGAGKSTLAKLVSRLYDPAAGTVLIDGHDLRDVTLESLHRQVGVVPQEPFLFAGTLRDNIAFARPSATDAQVMAAIEAVGLTDLVDRSPGGVHTILHERGQSVSSGERQLIALARVFVAEPRIVILDEATSSLDLRSELRVEAAIQRLLQGRTAILVAHRLSTAARADRVIVVDDGRIQESGPHAELVAAGGRYAAMYATWQSHHPVRDDRP
>AP019371.1|BBH71467.1|8825860_8827630_+|hypothetical-protein
MTSPPRRAPKAGIDPDPGKSWLRRAWPLVRAHRALLITSLVLSFIGLIVQVQIPDLVRIGIDDALVARTESLSRYVWLIAILAVAQGVINFFARLYLLRTAYEMEYDLRNTVFGHLMRMSYGFYDRVQSGELMSRATSDIRAVQMYLAFGPSILVQCTIAVIAFGLMVSINAPLAVVAMATMPLIAFLGVRMRKAIFPVSWLIQSRLAGVATVVDENIQGVRIVKAFAAEQRQISALSAAADRVRWAYTTDARIRSRWMPVMDNLSRVGLALVLLVGGLMVLGGDATIGTIVAFNSYVLMLQPPFRMLGMIIMMGQRAAASAQRIYEILDTKADISEPSEPAAPPPRGAIRFEDVRFAYPDGTIGLDGLTLDISPGETVALVGATGSGKSTVGRLAARFYDADAGRVLLDGQDVRDYRLATLRDRVGIVPDEPFLFSVSLHENIAFGRPGAGRDEVEAAALAAGADEFIRDLPDGYDTVVGERGYTLSGGQRQRVAIARALLVNPPVLILDDATSAVDVRVEHEIHSSLRGLMEGRTTVVVAHRLATIGLADRVVLIEDGRVVADGAHADLLANSPRYASVLAAQEVSA
>AP019371.1|BBH71466.1|8824889_8825795_-|hypothetical-protein
MMRRIAVAAVAAVAALTLSGLAAPARAAGVQTWTGTVDWVADGDTLRVDVHGDGTSALKSIRLIGIQAMEQTVYSPKPSKRRGECHSLAATARVEQLVEAGGNKVRLTALNASSKSGERPLRSAAVKIGGTWQDIGLDLVGRGLALWLPFSGEWTWDQRYLAAAKAASRAHRGLYDTDSCGAGPVANLGLTVNPDPDGSDAANLNGEYFVLRNAEKKAVNLTGWWVPDSAYRRYTFPHGTTIAAGGTLTVHVGKGRNTATDHYWGLDHPIFTNVDPAGHGYGDGGYLFDPQGDLRAWQIYP
>AP019371.1|BBH71465.1|8824233_8824899_+|thymidine-kinase
MVPVASSVQQPVVVPRQRAMAPVFHELTLFHGSMGAGKSTLALQNAYNRRQAGRPGVLLTSMDRAGSGVLSSRLGVAADAIEVLDGADLVTLIEQQVPAGGFVIVDEAQFLRPEQVEQLALAVDELHVDVDCYAISTDFMSRLFPGSQRLLELADRIVSLQVEVTCWCGRPGRQNARIEDGRVARTGAQVAVGDIDEAAEVTYRVLCRRHWRDGDAGPHQG
>AP019371.1|BBH71464.1|8822838_8824182_+|putative-NADH-dehydrogenase
MRHRVVVVGAGFGGLFAIKALRRADVDITLINGTAYHLFQPLLYQVATGILSEGEVAPPIREVLKRQKNVDVRLGWVQDVDVANKVVSVSGPGIEYTVEYDTLIVAAGASQSYFGNDQFADFAPGMKSIDDALELRARIFGAFEVADLQTDPADKERWLTFVVVGAGPTGTEMAGQIAELAHRTLPEQYRHIDTRKSRILLVDAVGAVLNTFGDRLSGRAKDELEKLGVEVKLNTKVVGVDTSGIEVETENGRERIPTMTKVWAAGVAAPTIATKLAEATGAKTDRAGRVLVEPDTTLPGHPEIFVLGDMMNLAGDDGRPLPGVAQVAIQSGRHAAEQIKRRLTGKPDKQPFKYFDKGSLATISRFSAVASIGKVHLSGFPAWVVWVAVHLFYLVGFKNRVTAVLHWAVSFLGRGRSERVATQQQAFARRALRLYGDPFKREAEESR
>AP019371.1|BBH71463.1|8822278_8822719_+|transcriptional-regulator
MTAPRPSPSLTPRLVFEMMTAERAVRRWIDARGGGTGIGAAGAGVLFYLHANDHALVGDVTAALCASPSGMSGLITRLEKAGFVAKNPDESDARAVRLTLTPLGREAASTARTVVRDLNTHLTEDFTPAELDVVARWLSHAATLTP
>AP019371.1|BBH71462.1|8821407_8822268_+|alpha/beta-hydrolase
MRNNEVRVGRIGATLHEPDDEPAAALVIHPATATPSRFYANFAAYLADNGIATVTYDYRGTGRSGSPRANRSLGMRDWITEDVPAVTAWTAARFPGLPQLAIGHSVGGHALALGYGGPGLSGLVILASHAASARAVPDPAERRRVRLLLHVVGPALGSVLGYVPARRLGLGEDIPAAAMRQWGGWAKLDGYFFDDPAMDAAARAATVTQPVLAVGFTDDKWATPASIDRLTSHLTAAPVERRTYSPADGGVDAIGHHGFLRRGVRDTLWPELLTWLQKQSSMTDSR
>AP019371.1|BBH71461.1|8821017_8821356_-|L-rhamnose-mutarotase
MTRVCFTLQVDPAKLDAYREAHAAVWPDMLRALAATGWHDYRLFLRPDGLLVGFLETDDFAAAQEAMARTEVNARWQAAMAGFFPALGDSRPDEGMLVLDQVFHLEEQLARI
>AP019371.1|BBH71460.1|8820587_8820920_-|hypothetical-protein
MAADPHIHIDARLGGQAASRAVLASAFGLAADLPPTVRSGCGLEVARAMTSVRPESVTCLTCREFGAEAHERLAAQVESLGVLPGSPLTPAQVHEAAAHHRDLARRFTRG
>AP019371.1|BBH71459.1|8819830_8820601_+|PaaX-family-transcriptional-regulator
MLLGDFVLDRDVCVFSGSVIDVFDRLGISSHATRSTLTRMVNRGLLRRQRDGRRMYFGLTARSTALLHDGRARIWRTGAVNDAWDGDWTLLCFSLPESWQRQRHDLRSQLAWAGFGPLQGGLWIAPGSVPAQDIVTDLGLSAHARVFHARADSLTDIAGMVRDAYDLAGLAAVYEEFLARWDGTPPFADPLAARLTLVAEWLGAIRRDPRLPVEHLPPAWPAVRAQKLFRELEVFSREPAREIADGLLELIPVSPE
>AP019371.1|BBH71469.1|8829892_8830810_-|penicillin-binding-protein
MSPQLSSSPYRPGVDDDFIQAARDLGVYGIHVHREGHEPLSHRFRSDDRVNLYSVAKTFTSVALGLAAADGRLTLDDLLLDHLPELRPLAADGFERVTLRHLVTMTSGTSHEWFADERIDAADLLHEIVAAPLTAEPGSVFRYTGSGPYAIGRVIARVTGADLRSFLTARIFRPLDLHNPAWHTCPLGHPFAESDLFLRTEELSRFARLLLNEGLWEGRRLIPADYVRSLTAAPVTTGHDGRFTTYGLGVWCEPGGIYRMDGRYGQYAVIDPARRTTVTVTAHAEQDADLLDAVHDLLLSRIPLP
>AP019371.1|BBH71470.1|8830885_8831293_+|hypothetical-protein
MTTPAEDLPYGWAPLVADRVLPTPALVTPGGRIAAGLLDLLLFVVTLGAGWLVWAMFTWPAGQTPAKRLLGHVVADGVTGRPFGRRRMAFREVCLKVALNVVTLTAFAWIDCFFVFTDQHRTLHDRIADSVVVER
>AP019371.1|BBH71471.1|8831332_8833852_-|hypothetical-protein
MDLSRTLAGFGTALLTATLLATPAPAGAAPGDSPSSRDFGNGPERNEIAALETFAARTLGAADAAQGTTRKQRGYPRQNELPVYPENPDDRSIKLGLIPYHAIAPKLNALQKASNRVSAEVIGKSAGGRDLYLVTVTAPESTAESARQDRWRHLIEDNPWAAKRDKSLESSYKTPVWINANIHGNEWEGTDGALRVIERLATATDTATADFLKTSRVYVTVTNNPDGRVAGTRANGAGFDINRDHATNSQPESRAVRDVVIGTQPFVMLDEHGYTGTTLIEPATPPHGQNYEYDLYIKHALPNALGMEAAIQKLGYAETTRADIPFRDYAPGDWDDWPPIFTPMYAIYQGAVGHTVEIPLAVNNANYNTLPVEELRRRSAINTDVAAATIEATLVYAGTNKASLLAGQIEQFRRGWAGEAAPVIPDGFVDGFGPEDRYSTTYPRAYVIPAGTPAATRLVNHLIDNDVRIKKAHRDFTVNGRRYAAGTYIVDMHQPKRGLANVLLEAGRDISDLVPQMYDISGWSHGLLWGATVDASRHAVPRVATSPVEEAVLQGSVDARKGSDLLLKLADGNDVRAVNELLAQGIKLRRADAATVVVPAEARPEASAVAKTLGVRFTAASRGTKGDVFDQPVIAGAVSADELFALKEMGFAVRTVSTAVLNAGASLDGVDTLIVSSGLSYAGLNATGKATVDAFLARGGGVVTRGATGAAFNAAAKLLPAVATAGRGDANGVVNVVNSGPVVGAGSLPHSFVYSPIWFTGSGFTVEQRYGATPLVAGHWQPTAAGTNGPAQAAGQAAVVSGATAGAGRAVLFGTEPLFRAHPKGLYAQYARALLWTAG
>AP019371.1|BBH71472.1|8833980_8834847_-|CoA-ester-lyase
MRSFLYVPGNRPQMLASALRRGADAIIVDLEDAVPPAEKDAARAAVATWLADQQPDAPIFVRVNVGDRGVDDARAVVAPAVRGLVVAKASPDQLSAVTAVLDDLDPAGAVSLVPLLETPQAILAAAAMAHAPRVARLQIGEADLAAELGVALGEDERELLFVRSAVVLASAAAGLDPPAAAVTTDFRDLDALRRTTLALKRLGFRGRACIHPAQLPVVHDVFTPTPAEVAEARDLIARFAAAGGGVCLDARGRMVDQAVVRDARRVLALAVGETAGNRLSRPGSGPIL
>AP019371.1|BBH71473.1|8834843_8836007_-|isovaleryl-CoA-dehydrogenase
MDFELSDEQRMFRDVLRDFVDREIRPVAQEWEESGRYPTEIVETMRSLGLFGLTVPEEYGGLGADMVSFALTFEEIAKGWMGIAGILGSHSLSCWLIARHGTSEQKAEFLPDLASGKRRTGIALTEPDAGTDLQGIATTAVRDGDHYVLNGRKTWITNARHADPLPVLCKTSVSADPPHKGMSVILVEAGTPGFTVERDLPKLGYKGTESCEVLLEDVRVPATRLLGGVEGRGMQQVLSGLETGRINVAARALGIAQAAYDEALRYAGQRRAFGRPIGDFQAIQLKIAEMAAQVQAARLLVHWAASRADGGHRVDMEAGMAKAFASEAAVFCALTAMQVHGGYGYSKEFVVERLYRDAPLMMIGEGTNDIQRVVIARALLAGKASIG
>AP019371.1|BBH71474.1|8836011_8836305_-|hypothetical-protein
MTLLIQHCPACRRYQYHPRPLCAGCGNPDLWSVEAAGTGTVDSFTTVHRADVPYTVARVRLTEGPIVLTHLIGIPEPRCDQPVRLTWHEGLAVFTSE
>AP019371.1|BBH71475.1|8836301_8837417_-|thiolase
MTGVAIAGAAECDLGKTGKSILELQTQAVTRALADAGLTLADVDGLATNGISRFSATQLADWLGVQPAWCDATFAGGAVFEMYVARAAQAIAAGQCSTVVISYASNQRSARSRKLTGVYEEGTPEAAIEEPYRPLYPISYYAMVAQRYLHTYGLDRADLAAVAVAARDRAQLNPQAWTYGKGPLTVEDVLGAPMISSPLGALDCCLVTDGGGAVVLTALDRARDLPKRPVTVLGYGEALTHTGMATAPDLLRTGAIDSGRRAFARAGLTPSDVDVVQLYDAFTISVPLGLEALGFAEPGGGLSAPIACNTGGGGLAYCHPGQFGVLLLVEAVRQLRGECGARQVPGASVALAHGTGGIFSSHATVILGVDG
>AP019371.1|BBH71476.1|8837413_8837791_-|hypothetical-protein
MSSDELIWERRIESPDMIAYAGATWDWHKLHYDADYLRERGLDRPVVDGQVFGAYLAIALREWFPGAAIGALSFRFTNLVFAGETIRCVGTPVREGSTITLALRIEVVEDGRIAVAPASATLTVP
>AP019371.1|BBH71477.1|8837777_8838236_-|hypothetical-protein
MTLLSGDLKARIGEEVVYTAPEPLGRAAIRYFALATGDTDPAHLAGDVAPPTLICETNQYANLPRDADGYAGHGWHLDVPGTRLVRGGNAYRFERPVLPTTIVTVRWKLAGITERVTGGGKRMLVVTSVATYTDQDGLVLAENEESLIYVER
>AP019371.1|BBH71478.1|8838232_8839192_-|hypothetical-protein
MTVYLPAVPGYPALAETGVAVTDVVHVTEYVTSAGLSLDAARAAFFGDHVVPVSRVPVEAIHGTDAPYAVGVTAYPGGGELLTDGDDVLRVAGGVVYLPSVHTTEGDFRSQYRWCLSRVSSLLSVAGLGMGSLVRTVDYTATATRAEYPRCGRPRKELLPGPVHPGAAGILVDVPVQRGAQVALDAIAAAGPLTVLNPGWARYDTLTYKPAVRAGDTVYLAGFGSLDPVTQLAVHEGDLTAQTEFIYHSIETVLAEAGATGANVTALVEYLTPAAVATYDATRQLREKHFPNAAVTSVVCSALLRPEFLLETVPTAVLG

Crispr_ID: AP019371_18

• CRISPR_ID: AP019371_18
• CRISPR_location: 8922216-8922305
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of AP019371_18

Consensus_repeat	Method
GCCTTCGAACAGCAATGGGTCACAGCCG	CRISPRCasFinder

spacers of AP019371_18

>18.1|8922244|34|AP019371|CRISPRCasFinder
AACGCATCGGCTGTGGCTCATCGCTGTCGCTTCG

CRISPR arrays and Neighbor proteins around AP019371_18

CRISPR arrays

The CRISPR arrays of AP019371_18

>merge|AP019371|18|8922216-8922305|CRISPRCasFinder
GCCTTCGAACAGCAATGGGTCACAGCCGAACGCATCGGCTGTGGCTCATCGCTGTCGCTTCGGCCTCCGAACAGCAATGGGTCACAGCCG

>AP019371|18|15|8922216-8922305|CRISPRCasFinder
GCCTTCGAACAGCAATGGGTCACAGCCG	AACGCATCGGCTGTGGCTCATCGCTGTCGCTTCG
GCCTCCGAACAGCAATGGGTCACAGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
AP019371.1|BBH71558.1|8923101_8924040_+|hypothetical-protein	unknown	unknown	unknown
AP019371.1|BBH71551.1|8916179_8917193_-|hypothetical-protein	unknown	unknown	gnl|CDD|224886
AP019371.1|BBH71565.1|8931095_8932028_-|hypothetical-protein	unknown	unknown	gnl|CDD|226951
AP019371.1|BBH71561.1|8927961_8928807_+|ribokinase	unknown	unknown	gnl|CDD|238579
AP019371.1|BBH71555.1|8921076_8922129_+|hypothetical-protein	unknown	unknown	gnl|CDD|224886
AP019371.1|BBH71560.1|8926320_8927511_-|elongation-factor-Tu	unknown	unknown	gnl|CDD|237184
AP019371.1|BBH71559.1|8924051_8926241_+|carbonate-dehydratase	unknown	unknown	gnl|CDD|319783
AP019371.1|BBH71564.1|8930436_8931099_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
AP019371.1|BBH71549.1|8914754_8915618_-|oxidoreductase	unknown	unknown	gnl|CDD|223786
AP019371.1|BBH71550.1|8915604_8916183_-|hypothetical-protein	unknown	unknown	gnl|CDD|133025
AP019371.1|BBH71546.1|8911525_8912482_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
AP019371.1|BBH71562.1|8928784_8929132_-|hypothetical-protein	unknown	unknown	gnl|CDD|378915
AP019371.1|BBH71547.1|8912465_8913644_-|hypothetical-protein	unknown	unknown	gnl|CDD|226082
AP019371.1|BBH71548.1|8913672_8914758_-|hypothetical-protein	unknown	unknown	gnl|CDD|176865
AP019371.1|BBH71553.1|8919597_8920080_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
AP019371.1|BBH71557.1|8922877_8923105_+|heavy-metal-transport/detoxification-protein	unknown	unknown	gnl|CDD|225328
AP019371.1|BBH71556.1|8922494_8922800_-|hypothetical-protein	unknown	unknown	gnl|CDD|197385
AP019371.1|BBH71554.1|8920082_8920955_-|carbon-monoxide-dehydrogenase-medium-subunit	unknown	unknown	gnl|CDD|224238
AP019371.1|BBH71563.1|8929375_8929990_+|hypothetical-protein	unknown	unknown	gnl|CDD|372992
AP019371.1|BBH71552.1|8917207_8919601_-|carbon-monoxide-dehydrogenase-large-subunit	unknown	unknown	gnl|CDD|131469

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
AP019371.1|BBH71551.1|8916179_8917193_-|hypothetical-protein	gnl|CDD|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	1.97328e-30
AP019371.1|BBH71565.1|8931095_8932028_-|hypothetical-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.63573e-39
AP019371.1|BBH71561.1|8927961_8928807_+|ribokinase	gnl|CDD|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	1.02947e-53
AP019371.1|BBH71555.1|8921076_8922129_+|hypothetical-protein	gnl|CDD|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	2.09611e-60
AP019371.1|BBH71560.1|8926320_8927511_-|elongation-factor-Tu	gnl|CDD|237184	PRK12736, PRK12736, elongation factor Tu; Reviewed.	0
AP019371.1|BBH71559.1|8924051_8926241_+|carbonate-dehydratase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
AP019371.1|BBH71564.1|8930436_8931099_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.76245e-69
AP019371.1|BBH71549.1|8914754_8915618_-|oxidoreductase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.61943e-43
AP019371.1|BBH71550.1|8915604_8916183_-|hypothetical-protein	gnl|CDD|133025	cd04182, GT_2_like_f, GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.89624e-52
AP019371.1|BBH71546.1|8911525_8912482_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.59528e-34
AP019371.1|BBH71562.1|8928784_8929132_-|hypothetical-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	9.13753e-11
AP019371.1|BBH71547.1|8912465_8913644_-|hypothetical-protein	gnl|CDD|226082	COG3552, CoxE, Protein containing von Willebrand factor type A (vWA) domain [General function prediction only].	4.54028e-70
AP019371.1|BBH71548.1|8913672_8914758_-|hypothetical-protein	gnl|CDD|176865	cd07823, SRPBCC_5, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	1.54537e-46
AP019371.1|BBH71553.1|8919597_8920080_-|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	5.28028e-72
AP019371.1|BBH71557.1|8922877_8923105_+|heavy-metal-transport/detoxification-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	2.74632e-14
AP019371.1|BBH71556.1|8922494_8922800_-|hypothetical-protein	gnl|CDD|197385	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156. This superfamily includes various transcriptional regulators that respond to stressors including Cu(I), Ni(I), sulfite, and formaldehyde. It includes CsoR (copper-sensitive operon repressor) from Mycobacterium tuberculosis (MtCsoR), Bacillus subtilis (BsCsoR), Thermus thermophilus (TthCsoR), and Staphylococcus aureus (SaCsoR), Mycobacterium tuberculosis RicR (regulated in copper repressor, MtRicR), Escherichia coli RncR (formally known as YohL, nickel and cobalt-sensitive), Alcaligenes xylosoxidans NreA (nickel-sensitive), E. coli FrmR (formally known as YaiN, formaldehyde sensitive), and Staphylococcus aureus CstR (CsoR-like sulfur transferase repressor, NWMN_0026.5, SaCstR). CsoR is Cu(I)-inducible, and regulates the expression of genes involved in copper homeostasis. For example, TthCsoR binds the promoter region of the copZ-csoR-copA operon, and represses expression of these genes, which encode the copper chaperone CopZ, CsoR, and the copper efflux P-type ATPase CopA, respectively. In the presence of excess Cu(I), TthCsoR binds this ion, and is released from the DNA, allowing expression of the downstream genes. TthCsoR also senses other metal ions such as Cu(II), Zn(II), Ag(I), Cd(II) and Ni(II). CsoRs form a homotetramer (dimer of dimers). In the case of MtCsoR, two Cys residues on opposite subunits within each dimer, along with a His residue, bind the Cu(I) ion. These residues are conserved in the majority of members of this superfamily. Exceptions include the functionally uncharacterized Bacillus subtilis YrkD where there is an Asn instead of His (C-N-C), E.coli RcnR where there is a Thr instead of the second Cys (C-H-T), or TthCsoR and E.coli FrmR where there is a His instead of the second Cys and which have an additional N-terminal His (not found in those family members having C-H-C) that may also be involved in metal binding (H-C-H-H). A conserved Tyr and a Glu residue facilitate allosteric regulation of DNA binding. SaCstR regulates genes predicted to function in sulfur metabolism; it is thought that oxidation of the intersubunit Cys pair to a mixture of disulphide and trisulphide linkages by sulfite, results in a reduced affinity of SaCstR for the operator DNA. SaCstR exists as a mixture of oligomeric states, including dimers, tetramers and octamers. The sequence of SaCstR was not available at the time this hierarchy was curated and therefore was not included. Escherichia coli RncR represses expression of the gene encoding the nickel and cobalt-efflux protein RcnA. The gene encoding Alcaligenes xylosoxidans NreA is part of the nre nickel resistance locus located on the pTOM9 plasmid from thisbacteria. Escherichia coli FrmR regulates the formaldehyde degradation frmRAB operon.	3.45436e-35
AP019371.1|BBH71554.1|8920082_8920955_-|carbon-monoxide-dehydrogenase-medium-subunit	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	3.32387e-85
AP019371.1|BBH71563.1|8929375_8929990_+|hypothetical-protein	gnl|CDD|372992	pfam14273, DUF4360, Domain of unknown function (DUF4360). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 200 and 228 amino acids in length. There is a conserved GCP sequence motif near the N-terminus.	2.57886e-81
AP019371.1|BBH71552.1|8917207_8919601_-|carbon-monoxide-dehydrogenase-large-subunit	gnl|CDD|131469	TIGR02416, Carbon_monoxide_dehydrogenase_large_chain, carbon-monoxide dehydrogenase, large subunit. This model represents the large subunits of group of carbon-monoxide dehydrogenases that include molybdenum as part of the enzymatic cofactor. There are various forms of carbon-monoxide dehydrogenase; Salicibacter pomeroyi DSS-3, for example, has two forms. Note that, at least in some species, the active site Cys is modified with a selenium attached to (rather than replacing) the sulfur atom. This is termed selanylcysteine, and created post-translationally, in contrast to selenocysteine incorporation during translation as for many other selenoproteins. [Energy metabolism, Other].	0

Protein sequences

>AP019371.1|BBH71555.1|8921076_8922129_+|hypothetical-protein
MRDIVDGLLAWRASGTEFALATVVNTWRSAPRQPGAAMAVNASGDVIGSVSGGCVEGAVYAAAQEVLETQKAQTHTYGVSDGDAFEVGLTCGGTIEIMIQPSSALAAVDAVLDAVAAGRPVATVTVPDAQLVVWPDSSVSGTLGDAELDRQAAQQAAGLLAHGRSAIVQACEREVFVQSYASPARMIVFGAIDFAAAVARIGKFLGYQVTVCDARGVFATPARFPEADEIVVEWPHRYLESTDVDERTVLCVLTHDPKFDIPLLEVALRTPARYIGAMGSRRTCADRVERLREAGVPETALSRLRAPIGLDLGARTPEETAVAIAAEIVALSWGGSGAPLSDLTAPIHRQ
>AP019371.1|BBH71554.1|8920082_8920955_-|carbon-monoxide-dehydrogenase-medium-subunit
MQVPAPFEYERATSVDQAIGLLERLGSSARLVAGGHSLLPMMKLRLANFEYLIDINDLHGELGYIRLGEDEVRIGAMTRHRELLESDALAAVFPVFRDAEKVIADPIVRNRGTLGGSLCQADPSEDLSAVCTTLDASCVIRGAHGERVVSMEEFHVGPYETAVADNEILTEIRIPVRPRGGSAYAKVERRAGDWAVVSAGAAVWLDDQGRFKDARVGLAAVGPNTTGIPEISEALRGQEPAEALYELAGAIAARSCDPATDTRGSADYKRHLADELTRRTLRKAVERARS
>AP019371.1|BBH71553.1|8919597_8920080_-|(2Fe-2S)-binding-protein
MQVTVTVNGVEYTKEIEGRLLLVHFLRDTLGLTGTHWGCDTSNCGTCVVWMDGEPVKSCTVLAAMAGGREVRTVEGLANGAELDPIQEGFRQCHGLQCGFCTPGMLMTCRALLDSNPDPTEGEIREAISGQICRCTGYSSIVRSVRWTAVHEAEAKAAAK
>AP019371.1|BBH71552.1|8917207_8919601_-|carbon-monoxide-dehydrogenase-large-subunit
MTDLQDKRETVFEDNDQKPVGFGRMLRKEDARLLRGRGRFVDDVQLPGMLHLAILRSPFAHANIVSIDTSAAEASPGVKAVVTGETLKGLGLAWMPTLSNDVQAVLATDKVRFQGQEVAFVVAEDRYQARDALELIDVEYDVLDPVIDVRQALAADAPIIRTDLDGKNDNHVFDWETGDEEETNRVFATADVVVKEDIVYPRVHPAPMETCGSVADFDPVEGKLRLWSTTQAPHAHRTLYAIVAGLPEHKIQVIAPDIGGGFGNKVPIYPGYVHSIVGSIVTGKPVKWMEDRSENLISTGFARDYIMQAEIAATAEGKILAIRTNVLADHGAFNGTAAPVKYPAGFFGVFTGSYDLQAAHCKMTAVYTNKAPGGVAYACSFRITEAVYLVERIVDVLAYELRMDPAELRLKNFIQPEQFPYTTKTGWVYDSGDYEPTMRLAMEMAGYDELRKEQAEKRARGELMGIGISFFTEAVGAGPRKNMDILGLGMADGCELRVHPTGKAVVRLSVKTQGQGHETTFAQIIAEELGIPPADIDVVHGDTDNTPFGLGTYGSRSTPVSGAAAALVARKVRDKAKLIASAMLEVSVADIEWVKGSFSVKGDPGKSVTIQDIAMRAHGAGDLPDGMEGGLEAQICYNPSNLTYPHGAYICVVDIDPGTSEVKVRRFIAVDDCGTRINPMIIEGQVHGGLTDGVGMALMEMISFDEDGNCLGASLMDYLIPTALEVPDWETGFTVTPSPHHPIGAKGVGESATVGSPPAIVNAVVDALKPFGVRHADMPLTPSRVWDAMRGQATPPI
>AP019371.1|BBH71551.1|8916179_8917193_-|hypothetical-protein
MTTTSTAERARQLTNARRPFVHATVVRAQEPTSARAGDDAVILADGSIEGFVGGVCAETSVRAAALDTLRDGNSMLLRVLPEDAAGFPETPGALVVVNPCHSGGAIEIFLRPVLPKPLVAVAGNTPIGTAVAELAAFLDFESAPAGTYAGATAAVVAGLGRDEERAIRGALDAGVGLIALVASHKRAAVVLDAMELSEDERERIRPHAGLDIGARTPKEIALAVCAEIVREIRLGGLAPRSIPAASKAAPHAEAAALAQAQPREAQPREAQPEKAQPEIVAGPTLPVGPATPAATAIDPICGMTVVIGENTPHGVVDGEDYWFCCPGCLKKFLASHR
>AP019371.1|BBH71550.1|8915604_8916183_-|hypothetical-protein
MTVTGLVLAAGGSRRLGEPKQLLPFRGRTLLDATLDMARACGFDDLLVTLGGSAEAVRAQVDLADVRVIENPDFSTGCGSSVSAAVPFLGDADRLVLLLGDQPGVRAPDVRRLALVPTPLGICRYTDGLGHPFLFRREVFGELTGLHGDKAVWKLLHSGRYPVTEVDAAGTVPIDVDTREDYERLLRSCEQS
>AP019371.1|BBH71549.1|8914754_8915618_-|oxidoreductase
MNNPDDVVQRLDAVDYLVDDGLAMAVFLALRLGKPLLLEGEPGVGKTAAAKALAQALDTPFIRLQCYEGLTAGEALYEWNYQRQLLHIRLAEAQGSTISDADLFTAAFLQERPILRAVRHAGPTPPVLLIDEIDRADDEFEALLFEFLGEAAITIPELGTFAATRPPIVVLTSNRSRDLHDALRRRCLYHWIEFPAADRAAAIVRRAVPGASAPLIRDATEFIGRVRRLDLDKAPGLAETIDWVSALAALGVTELADANVLRTIGTIAKTPDDRDLVAGAVHQETRS
>AP019371.1|BBH71548.1|8913672_8914758_-|hypothetical-protein
MKITNEFVVHTPIDRAWRVLTDLEGIAPCMPGAQLTGVEGEVYKGRVKVKVGPVISDFTGTAQFTAKDDESYRAVIDAKGRDARSAGNAAAVVTAWLTPSGDDSTQVNVETDLKISGKLAQFGSGMIKEVSGKLLAQFVANLEKKLAEDDASSSTIAGVGDGGQAASGAGAAEGASSSKIAGTASGAGTASGAGTASGAGTASGVGAAEGGVSAAAVETAPATAVALGSVAPGTPDGAGDISVMSPAVAPDPSAGTVEPAAGRTEVAEGTPDPIAPLNVPDAELIKAADAPAAAEARTEAPAGASTTVPAAGSGERKIESAEPEALDLLEVAGGSIYKRAIPVAIGVAVVAAVVVWAVVRP
>AP019371.1|BBH71547.1|8912465_8913644_-|hypothetical-protein
MLLRGIDRAAFAVALVARLRRAGLRCGITETDDLVRALRVSPPVGRHALYWTARITLVRSQADLAVFDEVFAAVFDDTAPLPLSRSALPPGRRDDGVHVKVPAGGDGTTAGGGLPWATLPPAVAAAEDDEDSGLRVPELRPSALAALAGRPFEELDETEIRALGAGLQAALLRWPQRRTRRHATDPAGRRVALRPTIARARRTGWEAITVVRQKPIREPRRVVLLCDVSESMRAQTTAYLTMMRAFALVTDAEVFAFATTLTRLTPVLRHASPEEAVDQASAAVTDRFGGTRIASNLKAVLDSHHGNALRGGVVIIASDGWDGDPPERMAAVMARLRRRAYRIIWLNPRAGTPGWTPGVAAMAAALPYCDRLMPAATFADISACVEAISSRA
>AP019371.1|BBH71546.1|8911525_8912482_+|LysR-family-transcriptional-regulator
MTPTQLRAYSAVVRLGSVKLAAAQLEVSESAVSLHIGQLRKELGDPLFSRAAGGLSFTPGGLRLASRATEMLGLQDITVLEVSAAGQGRRLLRAGASSLFAEHAAPGLIELFANRAADLDLELSVRNPGSFVEALLERTIDIAIGPPPLLPDPAVVCRPVMYYKIVTVASPDHPLAGTQPTLRQLREQTWLLGPSAVADSGAIRTLVRRLGVPDDRQQIFQSHAAAVDEAKRGRGVAAALAFTVAPEIRKGHLVSFCGSHATIEEVWHSITLAEPATPSAAGELARFASTPRAIQAMMRGTGINKSRFRPSVHVTLWS
>AP019371.1|BBH71556.1|8922494_8922800_-|hypothetical-protein
MSVMTNPAPTRGYTATKDNLQSRLRRIEGQVRGIERMVEDDRYCIDILTQISAIQAALDKVALGLLDGHARHCMHEGAQEGRADEMASELMAAVGRLMKRG
>AP019371.1|BBH71557.1|8922877_8923105_+|heavy-metal-transport/detoxification-protein
MYSEGMQTTTYSVTGMTCEHCVNSVSEEVGRITGVTGVEVDLASGQVAVTSEGPLDRAAVAAAVDEAGYELAVTP
>AP019371.1|BBH71558.1|8923101_8924040_+|hypothetical-protein
MRTGAKLAAYATGLIAIFGVSAGAGAAIGPDGTPPAAEPAHTGTAAHDEPAGHAEPTAHAEPTGHGEPTATASGDHGGGHGSGGSELPGGLQISQDGYRLETITTALSTGAAEPFAFRIRDEHGATVTDYTVSHEKELHLIVVRRDLAHYQHVHPVRDADGTWTVPLRVGAAGQYRVFADFETGGHDLTLGADVPAPGDYQPRPLPHSAKTTTAGGYQVTYDGDFLKGDVSFTVTKDGKQITTEPYLGARGHLVALREGDLAYLHVHPTDPDGLAFHAEVPSAGVYRLYLDFQHDGKVHTAEFTADTGHTHQ
>AP019371.1|BBH71559.1|8924051_8926241_+|carbonate-dehydratase
MNRIELAIGGMTCASCASRIEKKLNRMDGVTATVNYATEKATVTVDGQVTTADLIATVEKTGYTATPDRSREESDVSRDPLYDRLRVSIALSVPVILLAMVPAWQFEYWQWASLTLAAPVVVYGGYPFHRAAAINLRHGAATMDTLVSLGTIAAFGWSLWALFFGTAGEPGMTHGFQFAVERTDGAGNIYLEAAAGVTTFLLAGRYFEHRSKRRAGAALRALLELGAKDVAVVRGGQEIRIPVASLRKDDRFVVRPGEKIATDGVVEEGSSAVDMSMLTGESVPVEVGPGAAVTGATVNAGGRLVVRATRVGADTQLAQMARLVEEAQSGKAEVQRLADRISGVFVPVVIALAVATLGWWAGTGSGWTAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPEVLESTRRVDTIVLDKTGTVTTGTMKLVATIPAPGEDADELLRLTASAEAASEHPIAAAIAAELGNPLPVGGFTSFQGLGVRAEVAGFEVTAGRLALLEQEGLAIPAAVKEAVASEEAAGRTAIVAGWDGAARGVLAVADTVKPTSRTAIDRLRALGLRPILLTGDNETVARAVGAEVGVDEVIAGVLPQDKVAVVKRLQSEGRVVAMAGDGVNDAAALAQADLGLAMGTGADVAIEASDLTLIRGDLTAAVDAIRLSRRTLRIIKSNLFWAFAYNVAAIPLAAAGLLNPMIAGAAMALSSVFVVTNSLRLRRFAPSR
>AP019371.1|BBH71560.1|8926320_8927511_-|elongation-factor-Tu
MAKSQFIRTKPHLNIGTMGHVDHGKTTLTAAITKVLAERDPATNRYVAFEGIDKAPEEADRGITITISHVEYETATRHYAHVDMPGHADYVKNMITGAAQVDGAILVVSAQDGSMPQTREHVLLAQRVGVPYLVVALNKADAVDDPELLDLVELEVRELLSEYGFPGGEVPVVRVSALKALDGDPHWAASIGELLQAVDDYIPIPPRELGEPFLMPIENTLTISGRGTVVTGKVERGELRAGEPVEIVGLGETVSSVATGLETFGKVLESAQAGDNAAILLRGVKREQVQRGQVVAAPGSVRPHRVFRARMYALTAAEGGRHTPFAADYRPQFYLHTTDVAGGIDLGDLDMVMPGDTLDAVTVTLGKAVALEPGMGFAVREGNRTVAAGTVTAVLD
>AP019371.1|BBH71561.1|8927961_8928807_+|ribokinase
MDVVVAGQLARDLVLLVDEVPEAGTSADARLRREMLGGKGANQAVALAQLGARPVLIAVRGDDRVGEELIEQARRDGIDVRYVACRESVPTGLIVEALDASGEWRYLQHLPEDVLLTEEDVDAAAPALRAADAVLVQLQQPGPAALAAARYGREGGALVVLDGELPARERDRLIALADVIRADEREASSLGAVSGPLIMIATSDGNVVRWKDGEEFIPLTDEKVVDTTGAGDALTAALTVGLLRGMSPIEAGHFAVAAAGATVGHVGGRPDLSGFKGFVAR
>AP019371.1|BBH71562.1|8928784_8929132_-|hypothetical-protein
MTDIDEAEINKAKFLEAFGRFAEGDTSVLSEILREDFVSHTPGAPAGRDAWIEFIKNSPIASAEIAIEHVIADDQFVVAHYSLTAGEVRESVVDIWRFEDGLIVEHWSVTEPQNP
>AP019371.1|BBH71563.1|8929375_8929990_+|hypothetical-protein
MLTALATGVMAVSSLTWTVAPPPADEMVIDVVTAMGSGCPKGSAEVTVSPDNKAFTVSYSKFLAQVGPEAKALDFRKNCQLQLDVLVPSGYTYAVAGADYRGYASLQEGVTASETAFYYFQGEQHTTKIKHEFQGYLEEEWQRSDHVELTAESFLPCGDKRYLNVNTELKVNGANADKQVTNWITMDSTDASLETVYHVEWKKC
>AP019371.1|BBH71564.1|8930436_8931099_-|DNA-binding-response-regulator
MTRVLLVDDQSLLRQSLAVIINSEPDLTVVGEAGDGVEAVLQARATRPDVVLMDVRMPRVDGLEATRRICADPALRDCRVLVLSMFELDEYVYEALQAGASGFLLKDARPEVLADAVRRTHRGESLFAPSILTRLVAHYVSVPRPDRLADTLRHLTRREVEVLALIGKGLSNEEIADSLLISVKTVKSHITHLMAKLKARDRAQLVIAAFNAALVQPRPV
>AP019371.1|BBH71565.1|8931095_8932028_-|hypothetical-protein
MQANPRPTWRTRAVPVVGAVATALVLAMCTVGASGPLTTVIPSLIGGSAVAAVLWAVRRWRADRADYERRLTEWAAAEAVLAERLHIARDLHDLVSHGLGLITVRTAATRRLPASPEVREALDDIEETSRHATAELRRMLTVLRDPSDPGPRNPLEDLRALPEIVRAAETTGLRPRLAADALGVVTQGVQVAVCRTVREALSNAARHAGPTGVDVRLRRDGPFVVVTVADEGPAPGGWHAVPGAGHGLDGLRERISSLGGTLTTTRAGNGFHLTARIPDHPPATDGEQATPHASDLHQVITAPRREGDGS

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
AP019371_9	9.4|4654533|18|AP019371|CRT	4654533-4654550	18	AP019371.1	4654565-4654582	0	1.0
AP019371_14	14.1|8642422|28|AP019371|CRISPRCasFinder	8642422-8642449	28	AP019371.1	8642167-8642194	0	1.0
AP019371_15	15.1|8707873|56|AP019371|CRISPRCasFinder	8707873-8707928	56	AP019371.1	8708255-8708310	0	1.0
AP019371_15	15.1|8707873|56|AP019371|CRISPRCasFinder	8707873-8707928	56	AP019371.1	8708554-8708609	0	1.0
AP019371_5	5.2|3791408|34|AP019371|PILER-CR	3791408-3791441	34	AP019371.1	3791296-3791329	1	0.971
AP019371_5	5.4|3791520|34|AP019371|PILER-CR	3791520-3791553	34	AP019371.1	3791296-3791329	1	0.971
AP019371_9	9.2|4654445|18|AP019371|CRT	4654445-4654462	18	AP019371.1	6518468-6518485	1	0.944
AP019371_9	9.2|4654445|18|AP019371|CRT	4654445-4654462	18	AP019371.1	6518505-6518522	1	0.944
AP019371_9	9.4|4654533|18|AP019371|CRT	4654533-4654550	18	AP019371.1	1092648-1092665	1	0.944
AP019371_15	15.1|8707873|56|AP019371|CRISPRCasFinder	8707873-8707928	56	AP019371.1	8708064-8708119	1	0.982
AP019371_5	5.4|3791520|34|AP019371|PILER-CR	3791520-3791553	34	AP019371.1	3791184-3791217	2	0.941

1. spacer 9.4|4654533|18|AP019371|CRT matches to position: 4654565-4654582, mismatch: 0, identity: 1.0

cgtggtggcgtggtggcc	CRISPR spacer
cgtggtggcgtggtggcc	Protospacer
******************

2. spacer 14.1|8642422|28|AP019371|CRISPRCasFinder matches to position: 8642167-8642194, mismatch: 0, identity: 1.0

ccgcacacaacaccagcccgcgtgcacc	CRISPR spacer
ccgcacacaacaccagcccgcgtgcacc	Protospacer
****************************

3. spacer 15.1|8707873|56|AP019371|CRISPRCasFinder matches to position: 8708255-8708310, mismatch: 0, identity: 1.0

ggcgtgtgcggtggccgccctcaggacggcggtgagcgcacacgcgaccggtgcgt	CRISPR spacer
ggcgtgtgcggtggccgccctcaggacggcggtgagcgcacacgcgaccggtgcgt	Protospacer
********************************************************

4. spacer 15.1|8707873|56|AP019371|CRISPRCasFinder matches to position: 8708554-8708609, mismatch: 0, identity: 1.0

ggcgtgtgcggtggccgccctcaggacggcggtgagcgcacacgcgaccggtgcgt	CRISPR spacer
ggcgtgtgcggtggccgccctcaggacggcggtgagcgcacacgcgaccggtgcgt	Protospacer
********************************************************

5. spacer 5.2|3791408|34|AP019371|PILER-CR matches to position: 3791296-3791329, mismatch: 1, identity: 0.971

agtgtttggtttgcgtgagctgggcgccgtgctg	CRISPR spacer
agtgttcggtttgcgtgagctgggcgccgtgctg	Protospacer
******.***************************

6. spacer 5.4|3791520|34|AP019371|PILER-CR matches to position: 3791296-3791329, mismatch: 1, identity: 0.971

agtgttcggtttgcgtgagctgggcgccgtcctg	CRISPR spacer
agtgttcggtttgcgtgagctgggcgccgtgctg	Protospacer
****************************** ***

7. spacer 9.2|4654445|18|AP019371|CRT matches to position: 6518468-6518485, mismatch: 1, identity: 0.944

cccggcggcccggcggcc	CRISPR spacer
cccgacggcccggcggcc	Protospacer
****.*************

8. spacer 9.2|4654445|18|AP019371|CRT matches to position: 6518505-6518522, mismatch: 1, identity: 0.944

cccggcggcccggcggcc	CRISPR spacer
cccgacggcccggcggcc	Protospacer
****.*************

9. spacer 9.4|4654533|18|AP019371|CRT matches to position: 1092648-1092665, mismatch: 1, identity: 0.944

cgtggtggcgtggtggcc	CRISPR spacer
cgtggtggcggggtggcc	Protospacer
********** *******

10. spacer 15.1|8707873|56|AP019371|CRISPRCasFinder matches to position: 8708064-8708119, mismatch: 1, identity: 0.982

ggcgtgtgcggtggccgccctcaggacggcggtgagcgcacacgcgaccggtgcgt	CRISPR spacer
ggcgcgtgcggtggccgccctcaggacggcggtgagcgcacacgcgaccggtgcgt	Protospacer
****.***************************************************

11. spacer 5.4|3791520|34|AP019371|PILER-CR matches to position: 3791184-3791217, mismatch: 2, identity: 0.941

agtgttcggtttgcgtgagctgggcgccgtcctg	CRISPR spacer
agcgttcggtttgcgtgagctgggcgccgtcgtg	Protospacer
**.**************************** **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	746119-746139	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	897659-897679	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	57790-57810	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	939816-939836	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	841283-841303	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	336623-336643	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	820838-820858	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	1410641-1410661	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	486048-486068	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	658082-658102	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	692696-692716	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	1071278-1071298	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	759616-759636	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	861229-861249	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	939627-939647	0	1.0
AP019371_4	4.1|2613307|21|AP019371|CRISPRCasFinder	2613307-2613327	21	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	657749-657769	0	1.0
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK894437	Microbacterium phage MonChoix, complete genome	29237-29263	2	0.926
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	352277-352308	2	0.938
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	186327-186353	3	0.889
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KT365402	Mycobacterium phage Tres, complete genome	66817-66843	3	0.889
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KX443696	Mycobacterium phage Laurie, complete genome	65975-66001	3	0.889
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH727546	Mycobacterium phage Eaglehorse, complete genome	66859-66885	3	0.889
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	352272-352303	3	0.906
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	352282-352313	3	0.906
AP019371_7	7.4|3926524|22|AP019371|CRT	3926524-3926545	22	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	593670-593691	3	0.864
AP019371_7	7.4|3926524|22|AP019371|CRT	3926524-3926545	22	NZ_CP024426	Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence	132456-132477	3	0.864
AP019371_7	7.4|3926524|22|AP019371|CRT	3926524-3926545	22	NZ_CP020445	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence	72230-72251	3	0.864
AP019371_7	7.4|3926524|22|AP019371|CRT	3926524-3926545	22	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	86111-86132	3	0.864
AP019371_7	7.4|3926524|22|AP019371|CRT	3926524-3926545	22	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	335247-335268	3	0.864
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KT281796	Mycobacterium phage Zakhe101, complete genome	53314-53340	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_022325	Mycobacterium phage Dylan, complete genome	53310-53336	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MN428052	Mycobacterium phage Smooch, complete genome	54793-54819	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_016435	Gordonia phage GRU1, complete genome	42337-42363	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	131904-131930	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH479927	Gordonia phage TimTam, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK801727	Gordonia phage ThankyouJordi, complete genome	9852-9878	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KU963255	Gordonia phage Nymphadora, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MT889398	Gordonia phage Herod, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK878898	Gordonia phage Zameen, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK919483	Gordonia phage Suscepit, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK112547	Gordonia phage Maridalia, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MT952844	Gordonia phage Bosnia, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH479912	Gordonia phage Eviarto, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK016492	Gordonia phage Bialota, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_031226	Gordonia phage BaxterFox, complete genome	9176-9202	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK820642	Gordonia phage Polly, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK814755	Gordonia phage Antonio, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK875796	Gordonia phage Tayonia, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KU963249	Gordonia phage Yeezy, complete genome	9186-9212	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MT639650	Gordonia phage Ohgeesy, complete genome	9176-9202	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KX557273	Gordonia phage BatStarr, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MK875793	Gordonia phage WelcomeAyanna, complete genome	9852-9878	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KU963257	Gordonia phage Kita, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_031097	Gordonia phage Zirinka, complete genome	9828-9854	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP026305	Streptomyces lunaelactis strain MM109 plasmid pSLUN1, complete sequence	49331-49357	4	0.852
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_004934	Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence	94481-94507	4	0.852
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP032053	Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence	72683-72712	4	0.867
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_048047	Caulobacter phage CcrBL9, complete genome	229083-229109	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP025961	Rhodococcus qingshengii strain djl-6-2 plasmid pDJL2, complete sequence	72018-72044	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH744424	Gordonia phage Turuncu, complete genome	50175-50201	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	JF923796	Gordonia phage GTE5, complete genome	43363-43389	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	469219-469245	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	AY129335	Mycobacterium virus Corndog, complete genome	52844-52870	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MN428058	Mycobacterium phage Krili, complete genome	53107-53133	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH020246	Mycobacterium phage SchoolBus, complete genome	53275-53301	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MT818418	Mycobacterium phage Shida, complete genome	53219-53245	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_004685	Mycobacterium phage Corndog, complete genome	52844-52870	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	JN698993	Mycobacterium phage Firecracker, complete genome	54948-54974	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH926062	Mycobacterium phage Vorrps, complete genome	53636-53662	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MG099943	Mycobacterium phage Familton, complete genome	53555-53581	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MG872838	Mycobacterium phage JangDynasty, complete genome	53358-53384	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH590592	Mycobacterium phage Ryadel, complete genome	54382-54408	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MN585964	Mycobacterium phage Blessica, complete genome	53862-53888	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	KJ829260	Mycobacterium phage YungJamal, complete genome	53614-53640	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_022057	Mycobacterium phage Catdawg, complete genome	53598-53624	5	0.815
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MT818425	Mycobacterium phage NiebruSaylor, complete genome	53029-53055	5	0.815
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	352287-352318	5	0.844
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	678862-678893	5	0.844
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	MF417990	Uncultured Caudovirales phage clone 10S_6, partial genome	6089-6120	5	0.844
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP015090	Pelagibaca abyssi strain JLT2014 plasmid pPABY2, complete sequence	33191-33222	5	0.844
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP031753	Rhodobacter sphaeroides strain EBL0706 plasmid p.B, complete sequence	133957-133988	5	0.844
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	759745-759774	5	0.833
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71689-71718	5	0.833
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	361514-361543	5	0.833
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	18771-18800	5	0.833
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP014303	Hymenobacter sp. PAMC 26628 plasmid unnamed, complete sequence	27573-27599	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP046321	Gordonia bronchialis strain FDAARGOS_676 plasmid unnamed1, complete sequence	57071-57097	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_013442	Gordonia bronchialis DSM 43247 plasmid pGBRO01, complete sequence	52824-52850	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	57535-57561	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP050098	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence	458748-458774	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NZ_CP053440	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eF, complete sequence	530067-530093	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1063118-1063144	6	0.778
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	MH744421	Arthrobacter phage Moki, complete genome	38814-38840	6	0.778
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	708452-708483	6	0.812
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1681960-1681991	6	0.812
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1682273-1682304	6	0.812
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1681961-1681992	6	0.812
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1681164-1681195	6	0.812
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1682272-1682303	6	0.812
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP047145	Streptomyces sp. HF10 plasmid plas1, complete sequence	40728-40757	6	0.8
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	291704-291733	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP015233	Epibacterium mobile F1926 plasmid unnamed3, complete sequence	4371-4400	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP050081	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence	501078-501107	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP050106	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence	21780-21809	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP025016	Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence	79939-79968	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP049731	Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence	496476-496505	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	1012791-1012820	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP025506	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence	21795-21824	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP050111	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence	21779-21808	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	491900-491929	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP030763	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence	461703-461732	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NC_012848	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence	256108-256137	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP022668	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence	474543-474572	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	1168170-1168199	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	LT559120	Nonomuraea sp. ATCC 39727 isolate nono1 genome assembly, plasmid: III	28633-28662	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP053206	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence	497672-497701	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	99571-99600	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP050092	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence	284716-284745	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	802712-802741	6	0.8
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	921140-921169	6	0.8
AP019371_4	4.2|2613352|27|AP019371|CRISPRCasFinder	2613352-2613378	27	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	246323-246349	7	0.741
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1114140-1114171	7	0.781
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	258771-258802	7	0.781
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	547590-547621	7	0.781
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	180602-180633	7	0.781
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP039640	Azospirillum sp. TSH100 plasmid p1, complete sequence	235992-236023	7	0.781
AP019371_7	7.2|3926404|32|AP019371|CRT	3926404-3926435	32	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	89467-89498	7	0.781
AP019371_7	7.2|3926404|32|AP019371|CRT	3926404-3926435	32	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1772568-1772599	7	0.781
AP019371_7	7.2|3926404|32|AP019371|CRT	3926404-3926435	32	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1753985-1754016	7	0.781
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	1021922-1021951	7	0.767
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	40843-40872	7	0.767
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	284721-284750	7	0.767
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	98442-98471	7	0.767
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP020371	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs417, complete sequence	24843-24872	7	0.767
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	324429-324460	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP035514	Haematobacter massiliensis strain OT1 plasmid pOT1-4, complete sequence	80969-81000	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	23469-23500	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	1028124-1028155	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_017659	Escherichia coli O83:H1 str. NRG 857C plasmid pO83_CORR, complete sequence	106135-106166	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_MF174860	Escherichia coli strain 6/14/6b plasmid pIncF-MU4, complete sequence	125955-125986	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP049701	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence	365579-365610	8	0.75
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	684370-684401	8	0.75
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	266392-266421	8	0.733
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	82977-83006	8	0.733
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	CP054917	Streptomyces sp. NA02950 plasmid unnamed, complete sequence	98238-98267	8	0.733
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	NC_016115	Streptomyces pratensis ATCC 33331 plasmid pSFLA02, complete sequence	86950-86979	8	0.733
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	MK249146	Blackfly microvirus SF02 isolate 036, complete genome	1856-1885	8	0.733
AP019371_9	9.1|4654393|30|AP019371|CRT	4654393-4654422	30	MH617089	Microviridae sp. isolate cthd782, complete genome	1832-1861	8	0.733
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	136829-136858	8	0.733
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	73154-73183	8	0.733
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP015092	Pelagibaca abyssi strain JLT2014 plasmid pPABY3, complete sequence	97748-97777	8	0.733
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP023993	Streptomyces malaysiensis strain DSM 4137 plasmid unnamed, complete sequence	33616-33645	8	0.733
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_LR027556	Epibacterium mobile isolate EPIB1 plasmid 4, complete sequence	145411-145440	8	0.733
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_014107	Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A, complete sequence	56834-56865	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	23750-23781	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP031569	Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence	16555-16586	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP012169	Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-210.894kb, complete sequence	80435-80466	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	CP032294	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence	99577-99608	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP033799	Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence	68223-68254	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP043512	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed1, complete sequence	130903-130934	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP026851	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1	56851-56882	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_AP019534	Enterobacter asburiae strain MRY18-106 plasmid pMRY18-106EAS_1, complete sequence	24583-24614	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP029719	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence	131541-131572	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_AP019633	Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence	26222-26253	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP020054	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0065 plasmid unitig_1, complete sequence	48315-48346	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_KX912253	Enterobacter asburiae strain H162620587 plasmid pJF-587, complete sequence	85583-85614	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_KX858825	Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence	57019-57050	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	4359-4390	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	145349-145380	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP039454	Enterobacter bugandensis strain 220 plasmid pSurvcare220, complete sequence	86465-86496	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP050011	Citrobacter sp. Y3 plasmid unnamed2, complete sequence	19437-19468	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP009855	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-22e, complete sequence	23332-23363	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP008907	Enterobacter hormaechei subsp. hoffmannii ECR091 plasmid pENT-4bd, complete sequence	91930-91961	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP027145	Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence	77653-77684	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_LT991956	Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2	76468-76499	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP022534	Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence	123943-123974	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP021777	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0053 plasmid unitig_2, complete sequence	14272-14303	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	92681-92712	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	MK471334	Enterobacter cloacae plasmid pNRZ-28021, complete sequence	45784-45815	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP035514	Haematobacter massiliensis strain OT1 plasmid pOT1-4, complete sequence	80974-81005	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	375890-375921	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	106395-106426	9	0.719
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP020811	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed2, complete sequence	65563-65594	9	0.719
AP019371_7	7.2|3926404|32|AP019371|CRT	3926404-3926435	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	498625-498656	9	0.719
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP017078	Novosphingobium resinovorum strain SA1 plasmid pSA3, complete sequence	334631-334660	9	0.7
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NC_021279	Mycobacteroides abscessus subsp. bolletii 50594 plasmid 2, complete sequence	68474-68503	9	0.7
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	JN698995	Mycobacterium phage Dori, complete genome	3977-4006	9	0.7
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_CP053905	Hymenobacter sp. BRD67 plasmid unnamed1, complete sequence	30771-30800	9	0.7
AP019371_13	13.1|8587405|30|AP019371|CRISPRCasFinder	8587405-8587434	30	NZ_AP022622	Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1	66707-66736	9	0.7
AP019371_1	1.1|1157965|32|AP019371|CRISPRCasFinder	1157965-1157996	32	CP003956	Rhodococcus opacus PD630 plasmid 7, complete sequence	8937-8968	10	0.688
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NZ_CP017991	Enterobacter cloacae complex sp. ECNIH7 plasmid pENT-1ac, complete sequence	123349-123380	10	0.688
AP019371_7	7.1|3926349|32|AP019371|CRT	3926349-3926380	32	NC_015963	UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS01, complete sequence	39529-39560	10	0.688
AP019371_7	7.2|3926404|32|AP019371|CRT	3926404-3926435	32	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	202651-202682	13	0.594

1. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

2. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

3. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

4. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

5. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

6. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

7. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

8. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

9. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

10. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

11. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

12. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

13. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

14. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

15. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

16. spacer 4.1|2613307|21|AP019371|CRISPRCasFinder matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 0, identity: 1.0

gccgacggcgcgacgcctgcc	CRISPR spacer
gccgacggcgcgacgcctgcc	Protospacer
*********************

17. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK894437 (Microbacterium phage MonChoix, complete genome) position: , mismatch: 2, identity: 0.926

cccgccaagaaggccacggccgcgaag	CRISPR spacer
cccgccaagaaggctccggccgcgaag	Protospacer
**************. ***********

18. spacer 7.1|3926349|32|AP019371|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 2, identity: 0.938

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcggggcggggcgg	Protospacer
**************** ********* *****

19. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 3, identity: 0.889

cccgccaagaaggccacggccgcgaag	CRISPR spacer
accgccaagaaggccactcccgcgaag	Protospacer
 ****************  ********

20. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KT365402 (Mycobacterium phage Tres, complete genome) position: , mismatch: 3, identity: 0.889

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggccgcggcggcgaag	Protospacer
 **************.**** ******

21. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KX443696 (Mycobacterium phage Laurie, complete genome) position: , mismatch: 3, identity: 0.889

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggccgcggcggcgaag	Protospacer
 **************.**** ******

22. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH727546 (Mycobacterium phage Eaglehorse, complete genome) position: , mismatch: 3, identity: 0.889

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggccgcggcggcgaag	Protospacer
 **************.**** ******

23. spacer 7.1|3926349|32|AP019371|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 3, identity: 0.906

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cgggcggggcggggcggggcggggcggggcgg	Protospacer
 *************** ********* *****

24. spacer 7.1|3926349|32|AP019371|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 3, identity: 0.906

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcggggcggggcgt	Protospacer
**************** ********* **** 

25. spacer 7.4|3926524|22|AP019371|CRT matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.864

gtggcgtggcgcggcggggcga	CRISPR spacer
acggcgtggcgcggcggggcgc	Protospacer
..******************* 

26. spacer 7.4|3926524|22|AP019371|CRT matches to NZ_CP024426 (Paracoccus yeei strain TT13 plasmid pTT13-4, complete sequence) position: , mismatch: 3, identity: 0.864

gtggcgtggcgcggcggggcga	CRISPR spacer
cgcgcgtggcgcggcggggcga	Protospacer
   *******************

27. spacer 7.4|3926524|22|AP019371|CRT matches to NZ_CP020445 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence) position: , mismatch: 3, identity: 0.864

gtggcgtggcgcggcggggcga	CRISPR spacer
cgcgcgtggcgcggcggggcga	Protospacer
   *******************

28. spacer 7.4|3926524|22|AP019371|CRT matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.864

gtggcgtggcgcggcggggcga	CRISPR spacer
cgcgcgtggcgcggcggggcga	Protospacer
   *******************

29. spacer 7.4|3926524|22|AP019371|CRT matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 3, identity: 0.864

gtggcgtggcgcggcggggcga	CRISPR spacer
cgcgcgtggcgcggcggggcga	Protospacer
   *******************

30. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KT281796 (Mycobacterium phage Zakhe101, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgccaagaaggccacggcccgccgc----	Protospacer
******************    *****    

31. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_022325 (Mycobacterium phage Dylan, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgccaagaaggccacggcccgccgc----	Protospacer
******************    *****    

32. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MN428052 (Mycobacterium phage Smooch, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgccaagaaggccacggcccgccgc----	Protospacer
******************    *****    

33. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_016435 (Gordonia phage GRU1, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
cccgccaagaaggccgccgccgcgacc	Protospacer
***************.* *******  

34. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggcgaagaaggccacggctgcgaag	Protospacer
 * ** **************.******

35. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH479927 (Gordonia phage TimTam, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

36. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK801727 (Gordonia phage ThankyouJordi, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

37. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KU963255 (Gordonia phage Nymphadora, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

38. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MT889398 (Gordonia phage Herod, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

39. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK878898 (Gordonia phage Zameen, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

40. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK919483 (Gordonia phage Suscepit, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

41. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK112547 (Gordonia phage Maridalia, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

42. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MT952844 (Gordonia phage Bosnia, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

43. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH479912 (Gordonia phage Eviarto, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

44. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK016492 (Gordonia phage Bialota, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcagccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

45. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_031226 (Gordonia phage BaxterFox, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

46. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK820642 (Gordonia phage Polly, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

47. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK814755 (Gordonia phage Antonio, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

48. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK875796 (Gordonia phage Tayonia, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

49. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KU963249 (Gordonia phage Yeezy, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

50. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MT639650 (Gordonia phage Ohgeesy, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

51. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KX557273 (Gordonia phage BatStarr, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

52. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MK875793 (Gordonia phage WelcomeAyanna, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

53. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KU963257 (Gordonia phage Kita, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcggccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

54. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_031097 (Gordonia phage Zirinka, complete genome) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gcagccaagaaggccacctccgcgaag	Protospacer
 * **************  ********

55. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP026305 (Streptomyces lunaelactis strain MM109 plasmid pSLUN1, complete sequence) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
tccgcctcgaaggccacggccgcgagg	Protospacer
.*****  *****************.*

56. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_004934 (Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence) position: , mismatch: 4, identity: 0.852

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gctgccaagaaggccgcggccgccaag	Protospacer
 *.************.******* ***

57. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP032053 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence) position: , mismatch: 4, identity: 0.867

gtgcgg-tggtgcgcctggtgcgcctggtgc	CRISPR spacer
-tgcggctggtgcggctggtgcggctggtgt	Protospacer
 ***** ******* ******** ******.

58. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_048047 (Caulobacter phage CcrBL9, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggccactgccgccgcg	Protospacer
 **************** ***** . *

59. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP025961 (Rhodococcus qingshengii strain djl-6-2 plasmid pDJL2, complete sequence) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggcgatggccgcgacc	Protospacer
 ************* *.********  

60. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH744424 (Gordonia phage Turuncu, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacggccgcgaag	CRISPR spacer
cccgccaagaaggccgccgccgcgtcc	Protospacer
***************.* ******   

61. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to JF923796 (Gordonia phage GTE5, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacggccgcgaag	CRISPR spacer
cccgccaagaaggccgccgccgcgtcc	Protospacer
***************.* ******   

62. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacggccgcgaag	CRISPR spacer
tccgccaagcaggccacggcggcgctg	Protospacer
.******** ********** ***  *

63. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to AY129335 (Mycobacterium virus Corndog, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgctaagaaggccacggcccgccgc----	Protospacer
*****.************    *****    

64. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MN428058 (Mycobacterium phage Krili, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

65. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH020246 (Mycobacterium phage SchoolBus, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

66. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MT818418 (Mycobacterium phage Shida, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

67. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_004685 (Mycobacterium phage Corndog, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgctaagaaggccacggcccgccgc----	Protospacer
*****.************    *****    

68. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to JN698993 (Mycobacterium phage Firecracker, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgccaagaaggccgcggcccgccgc----	Protospacer
***************.**    *****    

69. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH926062 (Mycobacterium phage Vorrps, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

70. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MG099943 (Mycobacterium phage Familton, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

71. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MG872838 (Mycobacterium phage JangDynasty, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

72. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH590592 (Mycobacterium phage Ryadel, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

73. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MN585964 (Mycobacterium phage Blessica, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

74. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to KJ829260 (Mycobacterium phage YungJamal, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
cccgctaagaaggccacggcccgccgc----	Protospacer
*****.************    *****    

75. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_022057 (Mycobacterium phage Catdawg, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

76. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MT818425 (Mycobacterium phage NiebruSaylor, complete genome) position: , mismatch: 5, identity: 0.815

cccgccaagaaggccacg----gccgcgaag	CRISPR spacer
ccggccaagaaggccacggcccgccgc----	Protospacer
** ***************    *****    

77. spacer 7.1|3926349|32|AP019371|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 5, identity: 0.844

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcggggcgtgagat	Protospacer
**************** ***********. . 

78. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cggccggggtggggcgtggcggggcgtggctc	Protospacer
 ** *****.********************  

79. spacer 7.1|3926349|32|AP019371|CRT matches to MF417990 (Uncultured Caudovirales phage clone 10S_6, partial genome) position: , mismatch: 5, identity: 0.844

ggggcggggcggggcgtggcgggg-cgtggcgg	CRISPR spacer
tgggcgggggggggcgtggcggggatgcggcg-	Protospacer
 ******** ************** .*.**** 

80. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP015090 (Pelagibaca abyssi strain JLT2014 plasmid pPABY2, complete sequence) position: , mismatch: 5, identity: 0.844

ggggcggggcggggcgtggcggggcgtggcgg-	CRISPR spacer
aaggcggtgcggggcgtgtcggggcg-ggcggc	Protospacer
..***** ********** ******* ***** 

81. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP031753 (Rhodobacter sphaeroides strain EBL0706 plasmid p.B, complete sequence) position: , mismatch: 5, identity: 0.844

ggggcggggcggggcgtggcggggcgtggcgg-	CRISPR spacer
ccggcggtgcggggggtggcggggcg-ggcggc	Protospacer
  ***** ****** *********** ***** 

82. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.833

-gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
cgcccgg-ggtgcccctggtacgcctggtgc	Protospacer
 *. *** ***** ******.**********

83. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 5, identity: 0.833

gtgc-ggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
-tgctgttggtgctcctggtgctcctggtgt	Protospacer
 *** * ****** ******** *******.

84. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 5, identity: 0.833

-gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
cgcccgg-ggtgcccctggtacgcctggtgc	Protospacer
 *. *** ***** ******.**********

85. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 5, identity: 0.833

-gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
cgcccgg-ggtgcccctggtacgcctggtgc	Protospacer
 *. *** ***** ******.**********

86. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP014303 (Hymenobacter sp. PAMC 26628 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggccaccgccgctgcc	Protospacer
 **************** ***** .  

87. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP046321 (Gordonia bronchialis strain FDAARGOS_676 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagcaggcctcggccgcgtga	Protospacer
 ******** ***** ******** ..

88. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_013442 (Gordonia bronchialis DSM 43247 plasmid pGBRO01, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagcaggcctcggccgcgtga	Protospacer
 ******** ***** ******** ..

89. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
cccgccccgaaggccacggccgcccgc	Protospacer
******  ***************  . 

90. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP050098 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
atcgccaagaaggcgacgaccgcgacc	Protospacer
 .************ ***.******  

91. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NZ_CP053440 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eF, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
atcgccaagaaggcgacgaccgcgacc	Protospacer
 .************ ***.******  

92. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
tttcccaagatggccacggccccgaag	Protospacer
... ****** ********** *****

93. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to MH744421 (Arthrobacter phage Moki, complete genome) position: , mismatch: 6, identity: 0.778

cccgccaagaaggccacggccgcgaag	CRISPR spacer
cccgccaagaaggccacggaagccgcc	Protospacer
*******************  ** .  

94. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 6, identity: 0.812

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcgggccgctccgc	Protospacer
**************** ****** **.  ** 

95. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcgggccgctccgc	Protospacer
**************** ****** **.  ** 

96. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcgggccgctccgc	Protospacer
**************** ****** **.  ** 

97. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcgggccgctccgc	Protospacer
**************** ****** **.  ** 

98. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcgggccgctccgc	Protospacer
**************** ****** **.  ** 

99. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggcggggcggggcggggcgggccgctccgc	Protospacer
**************** ****** **.  ** 

100. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP047145 (Streptomyces sp. HF10 plasmid plas1, complete sequence) position: , mismatch: 6, identity: 0.8

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
cggtgctggtgcggctggtgcggctggtgc	Protospacer
  *.* ******* ******** *******

101. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 6, identity: 0.8

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
gtgtggtggtgctcctggtgcgcgagttcc	Protospacer
***.******** **********  * * *

102. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP015233 (Epibacterium mobile F1926 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gacgggggtggccggtggccgggtggccgc	Protospacer
. .  ***.*********************

103. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP050081 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

104. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP050106 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

105. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP025016 (Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

106. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP049731 (Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

107. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

108. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP025506 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

109. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP050111 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

110. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

111. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP030763 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

112. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NC_012848 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

113. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP022668 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

114. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

115. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to LT559120 (Nonomuraea sp. ATCC 39727 isolate nono1 genome assembly, plasmid: III) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
agctggggcggccggtggcccggtggacgg	Protospacer
* .* *************** ***** ** 

116. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP053206 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

117. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

118. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP050092 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gattgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

119. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

120. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ggttgcggcggccggtggccgggtcgcggc	Protospacer
. **  ****************** ** **

121. spacer 4.2|2613352|27|AP019371|CRISPRCasFinder matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 7, identity: 0.741

cccgccaagaaggccacggccgcgaag	CRISPR spacer
gccgccaagaaggccatggccgatccc	Protospacer
 ***************.*****     

122. spacer 7.1|3926349|32|AP019371|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.781

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cggtgcgggcgtggcgtggcgtggcgtggcgc	Protospacer
 **   ***** ********* ********* 

123. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 7, identity: 0.781

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggccgggcggggcggggcgggggtagggcg	Protospacer
***** ********** *******   **  *

124. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.781

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggccgggcggggcggggcgggggtagggcg	Protospacer
***** ********** *******   **  *

125. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 7, identity: 0.781

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggccgggcggggcggggcgggggtagggcg	Protospacer
***** ********** *******   **  *

126. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP039640 (Azospirillum sp. TSH100 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cgagcggggcggggccgggcggggcggcgctg	Protospacer
 *.************  *********  ** *

127. spacer 7.2|3926404|32|AP019371|CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

aagacgtggcgtggcgtggcgcggcgagacgt	CRISPR spacer
gcgtcgtggcgtggcgtggcgtggcgtgatgg	Protospacer
. * *****************.**** **.* 

128. spacer 7.2|3926404|32|AP019371|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 7, identity: 0.781

-aagacgtggcgtggcgtggcgcggcgagacgt	CRISPR spacer
cgagat-cggcgtggcgcggcgcggcgcgacgg	Protospacer
 .***. .*********.********* **** 

129. spacer 7.2|3926404|32|AP019371|CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.781

-aagacgtggcgtggcgtggcgcggcgagacgt	CRISPR spacer
cgagat-cggcgtggcgcggcgcggcgcgacgg	Protospacer
 .***. .*********.********* **** 

130. spacer 9.1|4654393|30|AP019371|CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 7, identity: 0.767

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
ctcggtcggtgcgcttggtgcgcttggtgc	Protospacer
 *  * .*******.********.******

131. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 7, identity: 0.767

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
tgccgacggtgcgccaagtgcgcctggtgc	Protospacer
   **..******** .*************

132. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
ggtcctcggtgcgccgggtgcgccgggtgc	Protospacer
*  *  .******** ******** *****

133. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 7, identity: 0.767

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gcttcgggagaccggtggccgggttgtggg	Protospacer
.******* *.************* *. * 

134. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP020371 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs417, complete sequence) position: , mismatch: 7, identity: 0.767

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gctgatcgcggccggtcgccgggtcgccgc	Protospacer
.**    ********* ******* *****

135. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP025613 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

-----ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
catcgggggcggggcatggcggggcggggcgt-----	Protospacer
     **********. **** **********     

136. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP035514 (Haematobacter massiliensis strain OT1 plasmid pOT1-4, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
gcggcggggcggggcggggcggggccgagtat	Protospacer
* ************** ********  .*.. 

137. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggccgggcggggcgtggccggtgccgacga	Protospacer
***** ************** **   .*.**.

138. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggccgggcggggcgtggccggtgccgacga	Protospacer
***** ************** **   .*.**.

139. spacer 7.1|3926349|32|AP019371|CRT matches to NC_017659 (Escherichia coli O83:H1 str. NRG 857C plasmid pO83_CORR, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cgcacagaacggggcggggcggggcggggcgg	Protospacer
 * .*.*..******* ********* *****

140. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_MF174860 (Escherichia coli strain 6/14/6b plasmid pIncF-MU4, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cgcacagaacggggcggggcggggcggggcgg	Protospacer
 * .*.*..******* ********* *****

141. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP049701 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg-	CRISPR spacer
cgggcggggcggggcggggcaggg-acagcgtc	Protospacer
 *************** ***.*** ...***  

142. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 8, identity: 0.75

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ggggccgggcggggcgtggccggtgccgacga	Protospacer
***** ************** **   .*.**.

143. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
ccgcgctggtgcgcctggtgcgcgccgcga	Protospacer
 .*** ***************** . *.* 

144. spacer 9.1|4654393|30|AP019371|CRT matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.733

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
cgtcgttggtgcgcctggtgcgccgtgacc	Protospacer
   ** ******************  *  *

145. spacer 9.1|4654393|30|AP019371|CRT matches to CP054917 (Streptomyces sp. NA02950 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
tggcggtggtgcgccgggtgcgcggcttgt	Protospacer
  ************* *******    **.

146. spacer 9.1|4654393|30|AP019371|CRT matches to NC_016115 (Streptomyces pratensis ATCC 33331 plasmid pSFLA02, complete sequence) position: , mismatch: 8, identity: 0.733

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
tcggagtggtgcgcctggtgtgcctgcagg	Protospacer
 .* .***************.*****  * 

147. spacer 9.1|4654393|30|AP019371|CRT matches to MK249146 (Blackfly microvirus SF02 isolate 036, complete genome) position: , mismatch: 8, identity: 0.733

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
tactgctggtgctcctggtgcgcctagtgg	Protospacer
   .* ****** ************.*** 

148. spacer 9.1|4654393|30|AP019371|CRT matches to MH617089 (Microviridae sp. isolate cthd782, complete genome) position: , mismatch: 8, identity: 0.733

gtgcggtggtgcgcctggtgcgcctggtgc	CRISPR spacer
tactgctggtgctcctggtgcgcctagtgg	Protospacer
   .* ****** ************.*** 

149. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 8, identity: 0.733

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gggtcgggcggccggtgtccgggtcgcgag	Protospacer
.  ************** ****** ** . 

150. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.733

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
aggcgatgcggccggtggacgggtagccgc	Protospacer
*  . . *********** *****.*****

151. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP015092 (Pelagibaca abyssi strain JLT2014 plasmid pPABY3, complete sequence) position: , mismatch: 8, identity: 0.733

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gataggggtggcgggtggccgggtggccat	Protospacer
. *  ***.*** ***************..

152. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP023993 (Streptomyces malaysiensis strain DSM 4137 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gcggagggcggccagtggccgggtgtcctg	Protospacer
.*   ********.*********** **  

153. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_LR027556 (Epibacterium mobile isolate EPIB1 plasmid 4, complete sequence) position: , mismatch: 8, identity: 0.733

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gataggggtggcgggtggccgggtggccat	Protospacer
. *  ***.*** ***************..

154. spacer 7.1|3926349|32|AP019371|CRT matches to NC_014107 (Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

155. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

156. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP031569 (Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

157. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP012169 (Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-210.894kb, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

158. spacer 7.1|3926349|32|AP019371|CRT matches to CP032294 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

159. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP033799 (Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

160. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP043512 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

161. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP026851 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

162. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_AP019534 (Enterobacter asburiae strain MRY18-106 plasmid pMRY18-106EAS_1, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

163. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP029719 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

164. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_AP019633 (Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

165. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP020054 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0065 plasmid unitig_1, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

166. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_KX912253 (Enterobacter asburiae strain H162620587 plasmid pJF-587, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

167. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_KX858825 (Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

168. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

-----ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cctgtgtggcgtggcgtggcgtggcgtggcgt-----	Protospacer
     * **** **** ********* *****     

169. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

-----ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
cctgtgtggcgtggcgtggcgtggcgtggcgt-----	Protospacer
     * **** **** ********* *****     

170. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP039454 (Enterobacter bugandensis strain 220 plasmid pSurvcare220, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

171. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP050011 (Citrobacter sp. Y3 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

172. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP009855 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-22e, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

173. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP008907 (Enterobacter hormaechei subsp. hoffmannii ECR091 plasmid pENT-4bd, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

174. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP027145 (Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

175. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_LT991956 (Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

176. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP022534 (Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

177. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP021777 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0053 plasmid unitig_2, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

178. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

179. spacer 7.1|3926349|32|AP019371|CRT matches to MK471334 (Enterobacter cloacae plasmid pNRZ-28021, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
acggtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
. **.   *** ********* ********* 

180. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP035514 (Haematobacter massiliensis strain OT1 plasmid pOT1-4, complete sequence) position: , mismatch: 9, identity: 0.719

-----ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
ccccggcggcggggcggggcggggcggggccg-----	Protospacer
     * ************** ********       

181. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
tcggcggggcggggggtgccggggcggtacat	Protospacer
  ************ *** *******  .*. 

182. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
tcggcctggcggggcgtggcggggccctgctc	Protospacer
  ***  ****************** . **  

183. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP020811 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
tgaagtgttcggggcgcggcggggcgcggcgg	Protospacer
 *..  *  *******.*********.*****

184. spacer 7.2|3926404|32|AP019371|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

aagacgtggcgtggcgtggcgcggcgagacgt	CRISPR spacer
gctgttcggcgcggcgtggcgcggcgaggcgt	Protospacer
.  .. .****.****************.***

185. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP017078 (Novosphingobium resinovorum strain SA1 plasmid pSA3, complete sequence) position: , mismatch: 9, identity: 0.7

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
ctgattggcggccggcggccggatggccga	Protospacer
 .  . *********.******.****** 

186. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NC_021279 (Mycobacteroides abscessus subsp. bolletii 50594 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.7

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gacgttagcgaccggtggccgggtggcctc	Protospacer
. . . .***.***************** *

187. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to JN698995 (Mycobacterium phage Dori, complete genome) position: , mismatch: 9, identity: 0.7

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
cagtcgggcggccggtgtccgggtcgatct	Protospacer
   ************** ****** * . .

188. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_CP053905 (Hymenobacter sp. BRD67 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
cagccaggcggccggtggcggggtggcgca	Protospacer
   .*.************* *******   

189. spacer 13.1|8587405|30|AP019371|CRISPRCasFinder matches to NZ_AP022622 (Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1) position: , mismatch: 9, identity: 0.7

acttcgggcggccggtggccgggtggccgc	CRISPR spacer
gacgttagcgaccggtggccgggtggcctc	Protospacer
. . . .***.***************** *

190. spacer 1.1|1157965|32|AP019371|CRISPRCasFinder matches to CP003956 (Rhodococcus opacus PD630 plasmid 7, complete sequence) position: , mismatch: 10, identity: 0.688

gtccggcagcgcaaccgctccgcagggcaggg	CRISPR spacer
ctgtattggcgcaaccgctccgacgggcaggc	Protospacer
 * .. ..**************  ******* 

191. spacer 7.1|3926349|32|AP019371|CRT matches to NZ_CP017991 (Enterobacter cloacae complex sp. ECNIH7 plasmid pENT-1ac, complete sequence) position: , mismatch: 10, identity: 0.688

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
actgtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
.  *.   *** ********* ********* 

192. spacer 7.1|3926349|32|AP019371|CRT matches to NC_015963 (UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS01, complete sequence) position: , mismatch: 10, identity: 0.688

ggggcggggcggggcgtggcggggcgtggcgg	CRISPR spacer
actgtcctgcgtggcgtggcgtggcgtggcgt	Protospacer
.  *.   *** ********* ********* 

193. spacer 7.2|3926404|32|AP019371|CRT matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 13, identity: 0.594

-----aagacgtggcgtggcgtggcgcggcgagacgt	CRISPR spacer
ccgtccgtgcgtggcgtggcgcggagcgacgg-----	Protospacer
      . .************.** ***.**.     

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	237917 : 244731	8	Staphylococcus_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>AP019371|237917:244731|DBSCAN-SWA
GATGACCGTGGTGCTTTCCTGCGCTGACGTCCGCAAGACCTTCGGCGATCACGTGATCCTCGACGGCCTCACCCTGGACGTGGCCGAGCACGAGGTGGTCGCCCTGATCGGCGCCTCCGGATCGGGCAAGTCCACGCTGCTGCGCTGCGTCAACCTGCTCGAACAGATCGACGACGGCACGATCCGGCTCGACGGCGAGGAGATCACCGACCCGCGGGCCGACCCGGACGAGGTCCGGCAGCGGATCGGGCTGGTCTTCCAGTCCTACAACCTGTTCCCGCACATGACGGTGCTCGACAACATCACCCTGGCGCCGGTGCGGGTGCACGGGAAGGACAGGGCCGAGGCGAAGGACCAGGCGATGACCTGGCTCAAACGGGTCGGCCTGGAGCAGAAGGCCACGGCGTACCCCGATCGGCTCTCCGGAGGTCAGCAGCAGCGCGTCGCGATCGTGCGGGCGCTGGTGAACAACCCGCGCCTGCTGCTGCTCGACGAGGTCACCTCGGCGCTCGACCCGGAACTGGTCGGCGAGGTCCTCACCATGATCAAGGACCTCAAGGCCGAGGGCATGACGATGGTGCTCGCCACCCACGAGATGGGCTTCGCGAAGCAGGTCGCCGACCGGGTCGCCTTCCTGGACGCCGGCCGGGTGCTCGAAGCCGGGCCGCCCGAGCAGGTGCTGGGCGACCCGGCCGAGGTGCGCACGCGCCAGTTCCTGGCGCGGATCATCGAGGCCGGTCGGCTGTAGGGCCTCAGCGGCCGAACATCGAGGGCTTCCCGATCTCGCGGAGGGCCAGGGCGGCGTCCAGGACGGCCACCGTCGCCTGCCAGCCCTTGTCCTCGATCGAGTCCTCCAGGCCGGCCCGGTCGCGGGCCTGACCCAGGCTCTGGACGGTGAGCACGCCGTGCGCCACAGGCGTGCTCTCGTCCAGCGCCACCCGGGTGAGGCCGCTGGTGACGGCGTCGCACACGTACTCGAAGTGCTGGGTCTCCCCCTTGATCACCACACCGAGCGCGACCACCGCGTCGTACTTGCGGGCCAGCGCCTGCGCCACGACCGGCAGCTCGACCGAGCCGGCGACGCGGTAGACGCCCACGTCGGTCACGCCGCACGCCTCGGCGGCCGACTTGGCCCGCTCGATCATGTGGGCGACCAGGTCGTTGTGCCACCGCGAGCCGACGATCCCGAGCTTCAGCCCGGCAGCGTCGACGGTCTCCATGTGCGGATCACCGAAGCCGGCCATCTGCGTCCCCCTTTTTCGACTTATTTCATGCTAAGCGGTGAGCGGTCAGCCCAAGGCCTCGAACAGGTGGCCCATGCGATCCCGCTTGGTACGCAGGTAGTGCACGTTCTCCGGGTGCAGCCGGACCGGCAGGGACTCCCGGCCGGTGACACGCAGGCCGTACCCCTCAAGCCCTGCTCTTTTCGCGGGGTTGTTGGTCAGCAGGCGCATCGACCGGATGCCCAGGTCGGCGAGGATCTGCGCGCCGGTGCCGTAGTCGCGCGCGTCGGCCGGCAGCCCGAGTTCGAGGTTCGCGTCGACGGTGTCCAGACCGCGGTCCTGCAGCTGGTACGCCTGAAGCTTGTGCAGCAGCCCGATGCCCCGCCCCTCGTGACCGCGCATGTAGAGCACCACACCCCGGCCGGCCGCCGCGACGCGTTCGAGAGCCGCGTCCAGCTGCGGGCCGCAGTCGCACCGCTTCGAGCCGAAGACGTCGCCGGTCAGGCACTCCGAGTGCACCCGGACCAGCACGTCCTCGCCGTCGCCGATCTCACCGAAGACGAGCGCCACGTGCTCGCCGTTGTCCGCCTCGGTGCGGTAGCCGACGGCGGTGAAGTCGCCGTGCTCGGTCGGCAGCTTGGTCTCCACGACCCGCTCGACCTGCCGGCCCTGGCGGAGGCTGAGGTACGCCACCAGCTCGGCGATCGAGACCAGCGTGAGGCCGTGCTCGGCCGCGAACTTCTCCAGGTCGGGCCGGCGCTGCATGGTGCCGTCGTCGTTCACCATCTCGCAGAGCACCCCGGCCGCCCGGGCGCCGGCGAGGACCGCCAGGTCGACCGAGGCCTCGGTGTGCCCGGGACGGCGCAGCACGCCACCCGGCTTGGCCCGCAGCGGGACGATGTGCCCCGGCCGGGACAGGTCGTTCGGCTGGGTCCGGGCCGAGGCGAGCAGGCCGATGGTCCGGGCGCGGTCGGCGGCCGAGATGCCGGTGGTCCCGCCCACCCGGGCGTCCACCGTCACGGCGTAGGCGGTCTTGTAGGAGTCCTGGTTGTATTCGACCATCGGCGGCAGGTCGAGCCGGTCGGCCTCGGCCTCGGGGATGGCCACGCAGATGTACCCGGACGTGTAGCGGACCATGAACGCCACCAGCTCCGGCGTGGCGTGCTCGGCCGCGAAGATGAGGTCGCCCTCGTTCTCGCGGTCCTCGTCGTCCACCACGATCACCGCTTTGCCGGCGGCGATGTCGGCGATCGCTTGCTCGACCTTCTCAAACATTGCGGCTCCCCAGCATCTTCTCGACGTACTTCGCGATCACGTCGACCTCGAGGTTGACCGGATCGCCGATGGCCTTGCTGCCCAGCACGGTGAGCTTCGAGGTGGCCGGGATCATCCCGACCGCGAAGCTGTCCGCCGTCACTTCCATCACCGTGAGCGAGACGCCGTCGACGGTGATCGAGCCCTTCTCCACGACGTACTTCTCCAGCTCGGCGGGGAGCGAGAACCGCACCACCTCCCACTGGTCGGCCGGCTCCCGGGCGATGATCCGCGCGACGCCGTCCACGTGGCCCTGCACCAGGTGGCCGCCGAGGCGGCTGTTCAGCGCGGCGGCCCGTTCCAGGTTGACCTGGCTGCCGACCGCGAGCGCGCCGAGCGAGCTGCGCCGCAGCGTCTCGCCCATCACGTCGGCGGTGAACACGCCGTCCTCGTTGTCGATCACGGTGAGACAGACCCCGTTCACCGCGATCGAGTCGCCGTGCCCCGCGTCCGACGTGACGAGCGGGCCGCGTACGGCGATGACCGCCGAGTCGTCACCCTCGGCTCCGGTGAGGCGGACGATCTCGCCCAGCTCTTCGACGATCCCGGTGAACATTCAGATCTCCTTCTTGGTGCGGAGCAGTGCTGTGAAACGCAGGTCGCCGCCGATCTGCGTGATGTCGGTGAACTCCAGTTCGACGGCCTCGGCGATGGTGCCGACACCGGCGTCGACCAGGGCGGTGCGGCCGTCGCCGAGCAGTTTCGGCGCGACGTACCCGATCACCCGATCGACAAGTCCGGCCGCCAGGAAAGCTCCGGCGAGGGTCGGACCGCCTTCGAGCAGCACGTTGCGCACGCCCCGGGCGTAGAGCTGGGTGAGCATCCGGGCCAGGTCGACGCGGCCTCCGGGGCCGCTTCCGACCGCGGCCGCGGAGACGATCCAGGTGGGTGCGGCGGCATCACGCACGCGGGCGTTCTCCGGGGTACGGCCGGACGAGTCGACCACCACACGCAGAGGTTGCTTGATCGCCAGCGTGCCGTCGCGCAGGTCCCGCACGGTGAGCTGCGGGTCGTCCGCCAGCACCGTGCCCACGCCGACCACGATGGCGTCGACGGTGCTGCGCAGCACGTGCACGTCGGAGCGGGACTCCAGGGACGAGATCCACTGGCTGGTGCCGTCCGCCGCTGCCGAGCGGCCGTCCAGGGTCGCCGCCATCTTCCAGGTCACGTAGGGCCGGCCGCGCCGGACCGCGGTGAGCCAGGCGACGTTGCCGGCCTCGGCCTCCTCACGGCGGACCCCGGTGACCACCTCGATGCCGGCCGACCGCAGCGTCGCCGCGCCCCCGGAGGCGACCGGGTTGGGATCGTCCACGCCGATCACGACGCGCCGCACCCCGGCCGCGATCAGGGCGTGCGAGCAGGGACCGGTCCGCCCGGTGTGGTTGCAGGGTTCCAGCGAGACGACACACGTGCCGCCCCGGGCCAGCTCACCCGCCTGGGCGAGGGCCACGATCTCCGCGTGCGGCCCTCCGGCGTACGCGTGGAAGCCCTCACCGACCACCTCACCGCCGGGCCCGAGCAGCAGGCAGCCGACGACCGGGTTGGGACTGGTCGTGCCGAGGCCACGGGCGGCCAGCGCGATCGCGCGGCGCATCGCCTCGTCCTCGGTCACCATCGGGCGTTTCCTCTCACGCGGTGCGGTCACGCGCTGTGAGGAAGCAAGACGACGAGGAATCGGGCAGGAGGGTACGCTTCGCGCACCCTCGACCAAGCCGGGCCACGCTTGTTCAAGCGGGCACGACTCGCCGATTCCGCGCGCTGTCTCCCATCCGGACTGTCTGATCGGGCTTTCGCCTGATCAACCGTCGGCCCTGGAGTCTCACCAGGTCCACCGGCCGCCGATGGTCGACGTCCGGGTCGCGGGCTTACCGCTGCTTGCGCAGTGGATCACCGCCGGTTCGGAATTTCACCGAGTCCCGCCAGCGCGTGGTGGGTCATCCCCGAGTCTTGCACGCAGCGGCGATTTTGCCACCTGGCCAGCGAGGTACTTCACATTCATCTAACCAGGGGAATGAATCGGCCGTGTCCAAATCCTACTGATTCAGTGGGCGTAGACAACGTCTACTCGATACTGGTAGACAGTGTCTATGGAACCTGACCAGGGACTCCGTGAGAGGCTCGTGCTCGTCGGCGCCGAGTTGCTCCGCACCGAAGGCCCGTCGGCGCTGTCCTTGCGGGAGATCGCCCGCCGCGCCGGCGTGTCACACGGCGCGCCGCGGCGCTACTTCCTCACCCACCTGGACCTGCTCGCCGCGATCGCCGGACTGGGCTTCGCCGATCTCGGTGACCGGATCACCACCGCGCTGGACGCCACCCCCGCCGACCCGCGCGACCGGGTGGCGGTGGTCGCCCGGGTCTACGCGCGGTTCGCCGCCGACGAACCCGGCATGTTCGAGCTGATGTTCCGGCAGGACCTGCTGGAGAGCGGCAACCTCGGCCTGCGCGACACCGGTCTGCCGGTGTTCCGGCTCCTCGTGGATCTGGTCAGCGCCGCCCGGCCGGATGCCGATCAGCCCGCCGTGGTCACCGCCGGAGCGCTCTGGGCCGGGCTGCACGGCGTGGTCCAGCTCTGGAACTGGGGCCGCCTGCCGTTCGCCACCGGACTGACGGACTCCGGCCCCCTGGTCGACGCCGTGATCACCGCACACCTGGGAGCAGCGCGATGACCCGTACCCCGCCCCTCTACGCACTGACCAGCGCGACCGTCGGCACCGCCGTGCGCCGCGTCTGGCGACCGCAGGTCGCGGGCCTGGAGAACATCCCGGCCGGCGGCGCGATCATCTGCGCCAACCATCTCTCCGTCGGCGACCAGTTCTTCCTCGGGGTGACGGTGCCGCGGCACATCGCGTTCTGGGCGAAGGCCGAATACTTCCAGCGGCGGCTCACCCGGCCCGTGGTCGCCGGCATGGGCGCCATCCCGGTCGAGCGCGCCGGTGGGCGGGCGGTACTCAGCGCCTTCGACGCGGCGGCGCCGATCCTGCGGGCCGGCGGGCTGGTCGCGGTCTTCCCCGAGGGCACGCGCTCACCCGACGGGCGTCTCCACCGGGGACGCACCGGCGCGGTCCGGCTGGCCACGCAGGCGGGCGTGCCGATCGTCCCGGCCGGCATCATCGGCACCCGCGGCCTGCGACCCAGCGGCATCCTGCGACCGGGCCGCCACCCGGTCTCGATCACCTTCGGCGAGCCCCTGACCGTCGGCGAGTCCTCGGTGCGGGACGACACCGACCGGCTCATCCGGCGGATCCAGGAGCTGACCGGCCAGGAGTACGTGCCGAGTTACGCCGTGCCCTCGTCCCGCCGGCGGTCGATCGCCACGTAGGAGCCCGGCTGCGACTTCGCGACCTTCTTCATCTCCGAGGCGACCGCGATGACCACCCGCGGGTCCGTGAAACTGCGGCCCTCGGAGGTCGACTGCGCCACCCCGATCGAGAGCGTCACCAGTGCCGCCTTCTGCTTGTTGCCGCGCCGGTCCGGCACCTCGATGAAGCCGCGCTGTGCGTCGTTCGGCTCGTAGAGGCGGTCGGCCGCGTTCTCGAAGTCGGTCACCATGCGCTTGGTCAGCGGCAGGACCTGGTCCGGCGTACAGATGAAGACGAAGTCGTCCCCGCCGATGTGGCCCAGGAAGATCGACGGCGGACCGGTCTGCGCGCTCGCCTTCTGCAGGCTGCGGGCCAGCGCGATGATGAAGTCGTCGCCGCGGTCGAAGCCGTAGACGTCGTTGACGCTCTTGAACCGGTCGATGTCGATGTAGCCCACCGAATATTCGCCGGTGGCGCGCATCCGCTCGCCGATCTCCCGGCGGACCCGCGCGTTGCCCGGCAGGCCGGTCAGCGGCGACACCTCGCGGGCGTCCTTGTTGCGGCGCAGCGTGGTGGTCACCCGGGCGATCAGCTCGGCCGTGTCGAACGGCTTGACCAGGTAGTCGTCGGCGCCCGCGGTCAGGCCGACCACCTTGTCCACGGTCATGCTCTTGGCGGTCAGCATGATCACCGGCAGCGCCGAGGTGAGCGGCTCGGCCCGCAGGCGGCGCACCAGCTCGACGCCGTCCATCCGCGGCATCATCCAGTCGACCACCGCCAGGCCCGGCCGGTGGTCCTCCATCAGCTCCAGCGCCTCCTGACCGTCCCTGGCCCGGATCACGTCGAAACCGTGGACCTTCAGGTTGAACTCGACGAAGCTCGCGATGTCCTGGTCGTCGTCGACCACCAGGATCAGATCGGGACCCTCCTCGGCCTCCAGCGCCAGTTCGCTCTCGGGCCGGGACTCCGCCTCGCTCAT

Protein sequences of DBSCAN-SWA_1

>AP019371|237917:244731|242540_243119_+|BBH63530.1|DBSCAN-SWA
MEPDQGLRERLVLVGAELLRTEGPSALSLREIARRAGVSHGAPRRYFLTHLDLLAAIAGLGFADLGDRITTALDATPADPRDRVAVVARVYARFAADEPGMFELMFRQDLLESGNLGLRDTGLPVFRLLVDLVSAARPDADQPAVVTAGALWAGLHGVVQLWNWGRLPFATGLTDSGPLVDAVITAHLGAAR
>AP019371|237917:244731|239205_240414_-|BBH63527.1|DBSCAN-SWA
MFEKVEQAIADIAAGKAVIVVDDEDRENEGDLIFAAEHATPELVAFMVRYTSGYICVAIPEAEADRLDLPPMVEYNQDSYKTAYAVTVDARVGGTTGISAADRARTIGLLASARTQPNDLSRPGHIVPLRAKPGGVLRRPGHTEASVDLAVLAGARAAGVLCEMVNDDGTMQRRPDLEKFAAEHGLTLVSIAELVAYLSLRQGRQVERVVETKLPTEHGDFTAVGYRTEADNGEHVALVFGEIGDGEDVLVRVHSECLTGDVFGSKRCDCGPQLDAALERVAAAGRGVVLYMRGHEGRGIGLLHKLQAYQLQDRGLDTVDANLELGLPADARDYGTGAQILADLGIRSMRLLTNNPAKRAGLEGYGLRVTGRESLPVRLHPENVHYLRTKRDRMGHLFEALG
>AP019371|237917:244731|241009_242068_-|BBH63529.1|DBSCAN-SWA
MVTEDEAMRRAIALAARGLGTTSPNPVVGCLLLGPGGEVVGEGFHAYAGGPHAEIVALAQAGELARGGTCVVSLEPCNHTGRTGPCSHALIAAGVRRVVIGVDDPNPVASGGAATLRSAGIEVVTGVRREEAEAGNVAWLTAVRRGRPYVTWKMAATLDGRSAAADGTSQWISSLESRSDVHVLRSTVDAIVVGVGTVLADDPQLTVRDLRDGTLAIKQPLRVVVDSSGRTPENARVRDAAAPTWIVSAAAVGSGPGGRVDLARMLTQLYARGVRNVLLEGGPTLAGAFLAAGLVDRVIGYVAPKLLGDGRTALVDAGVGTIAEAVELEFTDITQIGGDLRFTALLRTKKEI
>AP019371|237917:244731|238668_239160_-|BBH63526.1|DBSCAN-SWA
MAGFGDPHMETVDAAGLKLGIVGSRWHNDLVAHMIERAKSAAEACGVTDVGVYRVAGSVELPVVAQALARKYDAVVALGVVIKGETQHFEYVCDAVTSGLTRVALDESTPVAHGVLTVQSLGQARDRAGLEDSIEDKGWQATVAVLDAALALREIGKPSMFGR
>AP019371|237917:244731|237917_238664_+|BBH63525.1|DBSCAN-SWA
MTVVLSCADVRKTFGDHVILDGLTLDVAEHEVVALIGASGSGKSTLLRCVNLLEQIDDGTIRLDGEEITDPRADPDEVRQRIGLVFQSYNLFPHMTVLDNITLAPVRVHGKDRAEAKDQAMTWLKRVGLEQKATAYPDRLSGGQQQRVAIVRALVNNPRLLLLDEVTSALDPELVGEVLTMIKDLKAEGMTMVLATHEMGFAKQVADRVAFLDAGRVLEAGPPEQVLGDPAEVRTRQFLARIIEAGRL
>AP019371|237917:244731|243115_243772_+|BBH63531.1|DBSCAN-SWA
MTRTPPLYALTSATVGTAVRRVWRPQVAGLENIPAGGAIICANHLSVGDQFFLGVTVPRHIAFWAKAEYFQRRLTRPVVAGMGAIPVERAGGRAVLSAFDAAAPILRAGGLVAVFPEGTRSPDGRLHRGRTGAVRLATQAGVPIVPAGIIGTRGLRPSGILRPGRHPVSITFGEPLTVGESSVRDDTDRLIRRIQELTGQEYVPSYAVPSSRRRSIAT
>AP019371|237917:244731|240406_241009_-|BBH63528.1|DBSCAN-SWA
MFTGIVEELGEIVRLTGAEGDDSAVIAVRGPLVTSDAGHGDSIAVNGVCLTVIDNEDGVFTADVMGETLRRSSLGALAVGSQVNLERAAALNSRLGGHLVQGHVDGVARIIAREPADQWEVVRFSLPAELEKYVVEKGSITVDGVSLTVMEVTADSFAVGMIPATSKLTVLGSKAIGDPVNLEVDVIAKYVEKMLGSRNV
>AP019371|237917:244731|243729_244731_-|BBH63532.1|DBSCAN-SWA
MSEAESRPESELALEAEEGPDLILVVDDDQDIASFVEFNLKVHGFDVIRARDGQEALELMEDHRPGLAVVDWMMPRMDGVELVRRLRAEPLTSALPVIMLTAKSMTVDKVVGLTAGADDYLVKPFDTAELIARVTTTLRRNKDAREVSPLTGLPGNARVRREIGERMRATGEYSVGYIDIDRFKSVNDVYGFDRGDDFIIALARSLQKASAQTGPPSIFLGHIGGDDFVFICTPDQVLPLTKRMVTDFENAADRLYEPNDAQRGFIEVPDRRGNKQKAALVTLSIGVAQSTSEGRSFTDPRVVIAVASEMKKVAKSQPGSYVAIDRRRDEGTA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
BBH63525.1|237917_238664_+	ABC transporter	G9BWD6	Planktothrix_phage	2.3e-28	36.9
BBH63526.1|238668_239160_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2I2L4Y7	Orpheovirus	3.1e-13	33.9
BBH63527.1|239205_240414_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	1.5e-85	44.1
BBH63528.1|240406_241009_-	riboflavin synthase subunit alpha	A0A2H4PQS5	Staphylococcus_phage	9.1e-31	41.5
BBH63529.1|241009_242068_-	putative bifunctional riboflavin biosynthesis protein RibG	A0A1V0SE20	Indivirus	1.4e-34	34.3
BBH63530.1|242540_243119_+	TetR family transcriptional regulator	NA	NA	NA	NA
BBH63531.1|243115_243772_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
BBH63532.1|243729_244731_-	hypothetical protein	W8CYM9	Bacillus_phage	6.6e-18	45.8