CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP030063	[Brevibacterium] frigoritolerans strain ZB201705 chromosome, complete genome	2 crisprs	csa3,DEDDh,cas3,DinG	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP030063_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030063_1

2638039-2638149

Orphan

Consensus_repeat	Method
TTTGGAGCAAATACTCGTGACTTTCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP030063_1

>merge|CP030063|1|2638039-2638149|CRISPRCasFinder
TTAGGAGCAAATACTCGTGACTTTCAAGCTTTTACTCGTGAATTTGGAGCAAATACTCGTGACTTTCATGCTTTTACTCGTGAATTTGGAGCAAATACTCGTGAATTTCAT

>CP030063|1|1|2638039-2638149|CRISPRCasFinder
TTAGGAGCAAATACTCGTGACTTTCAA	GCTTTTACTCGTGAATTTGGAGCAAATACTCGTGACTTTCATGCTTTTACTCGTGAA
TTTGGAGCAAATACTCGTGAATTTCAT

Protein	Signature genes	Signature genes Name	Protein_function
CP030063.1\|AZV61378.1\|2647852_2648587_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
CP030063.1\|AZV61366.1\|2632009_2633398_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
CP030063.1\|AZV61361.1\|2627816_2628056_-\|phosphatidylserine-synthase	unknown	unknown	gnl\|CDD\|379161
CP030063.1\|AZV61365.1\|2630835_2631621_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181585
CP030063.1\|AZV61363.1\|2629194_2629755_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|379658
CP030063.1\|AZV61368.1\|2635789_2635990_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371707
CP030063.1\|AZV61376.1\|2643619_2644846_-\|ROK-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224851
CP030063.1\|AZV61375.1\|2642540_2643620_-\|iron-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270270
CP030063.1\|AZV61381.1\|2650597_2651935_-\|YjiH-family-protein	unknown	unknown	gnl\|CDD\|225851
CP030063.1\|AZV61379.1\|2648583_2649228_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
CP030063.1\|AZV61380.1\|2649301_2650078_-\|glutamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270337
CP030063.1\|AZV61370.1\|2637594_2637810_-\|hypothetical-protein	unknown	unknown	unknown
CP030063.1\|AZV61367.1\|2634171_2635515_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
CP030063.1\|AZV61377.1\|2645100_2647608_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376836
CP030063.1\|AZV61373.1\|2639727_2641416_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
CP030063.1\|AZV61364.1\|2629965_2630817_+\|glucose-transporter-GlcU	unknown	unknown	gnl\|CDD\|227309
CP030063.1\|AZV61362.1\|2628463_2629009_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|235811
CP030063.1\|AZV61372.1\|2638227_2639712_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|180664
CP030063.1\|AZV61374.1\|2641412_2642525_-\|spermidine/putrescine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
CP030063.1\|AZV61369.1\|2635986_2637465_+\|sodium:solute-symporter-family-protein	unknown	unknown	gnl\|CDD\|223664

Protein	Function_ID	Function_description	E-value
CP030063.1\|AZV61378.1\|2647852_2648587_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	6.59164e-162
CP030063.1\|AZV61366.1\|2632009_2633398_-\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
CP030063.1\|AZV61361.1\|2627816_2628056_-\|phosphatidylserine-synthase	gnl\|CDD\|379161	pfam13396, PLDc_N, Phospholipase_D-nuclease N-terminal. This family is often found at the very N-terminus of proteins from the phospholipase_D-nuclease family, PLDc, pfam00614. However, a large number of members are full-length within this family.	3.14637e-05
CP030063.1\|AZV61365.1\|2630835_2631621_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|181585	PRK08936, PRK08936, glucose-1-dehydrogenase; Provisional.	3.40617e-162
CP030063.1\|AZV61363.1\|2629194_2629755_-\|thioredoxin-family-protein	gnl\|CDD\|379658	pfam14595, Thioredoxin_9, Thioredoxin.	6.38468e-43
CP030063.1\|AZV61368.1\|2635789_2635990_+\|hypothetical-protein	gnl\|CDD\|371707	pfam11755, DUF3311, Protein of unknown function (DUF3311). This is a family of short bacterial proteins of unknown function.	5.51704e-14
CP030063.1\|AZV61376.1\|2643619_2644846_-\|ROK-family-transcriptional-regulator	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.31194e-69
CP030063.1\|AZV61375.1\|2642540_2643620_-\|iron-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270270	cd13552, PBP2_Fbp_like_6, Substrate binding domain of an uncharacterized ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. This periplasmic domain (Fbp) has high affinity for ferric iron and serves as the primary receptor for transport. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	7.37599e-149
CP030063.1\|AZV61381.1\|2650597_2651935_-\|YjiH-family-protein	gnl\|CDD\|225851	COG3314, COG3314, Uncharacterized protein conserved in bacteria [Function unknown].	5.31223e-122
CP030063.1\|AZV61379.1\|2648583_2649228_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	7.53084e-81
CP030063.1\|AZV61380.1\|2649301_2650078_-\|glutamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270337	cd13619, PBP2_GlnP, Glutamine-binding domain of ABC transporter, a member of the type 2 periplasmic binding fold protein superfamily. Periplasmic glutamine binding domain GlnP serves as an initial receptor in the ABC transport of glutamine in eubacteria. GlnP belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.78413e-108
CP030063.1\|AZV61369.1\|2635986_2637465_+\|sodium:solute-symporter-family-protein	gnl\|CDD\|223664	COG0591, PutP, Na+/proline symporter [Amino acid transport and metabolism / General function prediction only].	3.28343e-63
CP030063.1\|AZV61367.1\|2634171_2635515_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
CP030063.1\|AZV61377.1\|2645100_2647608_+\|hypothetical-protein	gnl\|CDD\|376836	pfam02585, PIG-L, GlcNAc-PI de-N-acetylase. Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.	2.23839e-16
CP030063.1\|AZV61373.1\|2639727_2641416_-\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	6.07904e-99
CP030063.1\|AZV61364.1\|2629965_2630817_+\|glucose-transporter-GlcU	gnl\|CDD\|227309	COG4975, GlcU, Putative glucose uptake permease [Carbohydrate transport and metabolism].	2.79979e-99
CP030063.1\|AZV61362.1\|2628463_2629009_+\|transcriptional-regulator	gnl\|CDD\|235811	PRK06474, PRK06474, hypothetical protein; Provisional.	1.71623e-76
CP030063.1\|AZV61372.1\|2638227_2639712_-\|argininosuccinate-lyase	gnl\|CDD\|180664	PRK06705, PRK06705, argininosuccinate lyase; Provisional.	0
CP030063.1\|AZV61374.1\|2641412_2642525_-\|spermidine/putrescine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	3.41249e-158

>CP030063.1|AZV61370.1|2637594_2637810_-|hypothetical-protein
MLMSNRSQFGVILILIAFVISITFCLNPEVLLRGGYDLAIDGLVVSRTLMIIFSLYLLVKIGDLFINRKDK
>CP030063.1|AZV61369.1|2635986_2637465_+|sodium:solute-symporter-family-protein
MNIALLIILAFLLLSIFLGIRSSKGKDMDLEQWTVGGRGFGAIFVFLLMAGEIYTTFSFLGGSGWAYGKGAPALYVLIYITLSYVLSYWLLPEIWRYAKENKLMSQSDFFVSKYKSPSLGILAALVGVVSMIPVIVVQLKGLGIIVSEASYGAISMSEAVWMGAISLTIYVMISGIHGSVWTAVIKDIMMVAIIGFLGIYLPIHYFGGFQPMFEAIDAAKPGFLKFPDQGLSVSWFISTVILLVFGFYMWPQVFSAVYSARSGKVFRKNAIISPLYTLMLLFVFFVGFTAILKVPGLVGANADLSLLRLSIETFDPWFIGIIGGAGLLTALVPGSMLLMSVATLLAKNVYKEFAPAVSDRHIVRLAKFLVPIIALIAVYFTLNGGETMSALILMGYSLITQLFPSLLFSLKRNNPINKFGAIAGIITGLAIVICITLSQSTIGTLFPSLPQAAKDLNVGIIALAVNFIVMITVSIAFRKHAVQLEPKAVNDI
>CP030063.1|AZV61368.1|2635789_2635990_+|hypothetical-protein
MKIIYTLTLVPFIGILGFLPFVNKIEPYVLGMPFNMFWMAMWVVLTSAILGIMYKLDPRNREGDQE
>CP030063.1|AZV61367.1|2634171_2635515_+|amino-acid-permease
MAKQELKRDLKNRHVQLIAIGGTIGTGLFLGSGKAIQLAGPSILFSYLIIGIALFFVMRTLGELLLSNAGYVSFTEFATEYVGPWAGFVTGWTYWFCWIMTAMADIIAVGVYMQYWFDIPQWIPALICLVILLGLNLLTVKLFGELEFWFAIIKVITIIALIVVGIILLIIGFNTNTGTVSLTNLWNHGGMFPNGISGFLLSLQLVVFSFVGVELVGVSAAETANPRKNIPSAINKIPVRILLFYVGAIFVILCVNPWTQLDATSSPFVEVFALIGIPVAAGIINFVVLTSAASACNSGLFSTSRILYTLSRNGEAPAKLEKLNKQAVPSNALFTSTIVVSIGALLSKLIPEQAFTVVTTISAICFIWVWSIILISHIKYSKTRPDLRAESTFKAPFTPFVNYVILGLFLFILIVMLFAEATRLSLLLTPIWFILLVILYNYRKKDS
>CP030063.1|AZV61366.1|2632009_2633398_-|amino-acid-permease
MSNKELKRGLESRHIQMIALGGTIGVGLFMGSASTIKWTGPSVMLAYAIAGIFIFFIMRSMGEMLYLEPTTGSFATFASSYIHPLAGYMTAWSNWFQWVIVGMSEIIAVGLYMQYWFPELPAWIPGVVAMIILGAANLISVKSFGEFEFWFALIKIITIILMIVAGLGLIFFGIGNGGDALGLSNLWENGGFFTGGWTGFFFALSLVVASYQGVELIGITAGEAKDPTKTVTKAIQSIIWRILIFYIGAIFVIVTVFPWDQLDDLGSPFVSTFAKIGITAAAGIINFVVITAAMSGCNSGIFSAGRMLYTLALNGQAPKVFAKVSKNGVPAYCTIAVLLGLGIGVILNYLAPPQVFLYVYSASVLPGMIPWFVLLISELKFRKVNAAEMEKHPFKMPLAPYSNYATIAFLLMVLVGMWINPSTRISLVVGIVFLALVIASYYMLKMDKRTPLDVKSDDEISG
>CP030063.1|AZV61365.1|2630835_2631621_+|SDR-family-NAD(P)-dependent-oxidoreductase
MYEDLEKKVVVITGAAKGLGKAMAERFGKEKAHVVLNYHTENGDHKEIIKTIEAAGGKAAAIQGDVSKEADVKKLLSFAVDTFGTIDIMINNAGIENEVPSEKLTLEDWQKVIDVNLTGMFLASREAISYMLDHGIKGNIINMSSVHDRIPWPHFVHYAASKGGVKMMTETLALEYAPKGIRINNISPGAIDTPINAEKFNDPKAKQEVINLIPMGYIGKPEQIAACAAWLASAESSYVTGLTLYADGGMTKYPGFQAGKG
>CP030063.1|AZV61364.1|2629965_2630817_+|glucose-transporter-GlcU
MEGFLFALLPALTWGSLVLVSEKLGGNSYNQTLGITIGSLLFAIMMSFINPPEWSSLVWIVGIISGIGWAFGQLFQFNSVKEIGVSKTVPISTGLQILGNTFFAVIIFREWNDKVTIIIGIVAIICLITGVLLTSYGDGDNKKEGSMKKGVFYLAISTVGYVTYVIVVRWNEVDGWSAILPQAIGMFLAALLLSIKHKPFNKYAGRNILTGMMWAVGNIGLLLANPKVGVAIAFSFSQMGIVISTLGGIFLLGEKKSKKQMAFVIIGCVLVIAGGIMIGFTKE
>CP030063.1|AZV61363.1|2629194_2629755_-|thioredoxin-family-protein
MTTLNEWFEKGIPAQEFVSSMKVHKENLQSIQQGFSTSAEDQDFFGALKKKELRVIVITEDWCGDAMMNIPILLNISEAANIETRMVLRDQNLELMDQYLTNGTARSIPIFIFIDKEGEEKAVWGPRAPKVQEFVMGLRSDLPAKDDERFEAEQKAVIKKITAAFAEEKHLWDEVYSSIKETLGSC
>CP030063.1|AZV61362.1|2628463_2629009_+|transcriptional-regulator
MINKAEILMHPVRIKITQALMRNRENGLTPLEMLKVIKDVPQATLYRHIQVLLDSGVIRIVKEKKVRSVSEKYYVLNEEEARLSGEEWKKSSNEKKVNYFSYYQLSLMTQYQNYLTKLEERDCAEDGSTFSLLELKLDDESFLNFQNELNDLMLKYYKATNQSAKQDSPIRTIGVTIIPES
>CP030063.1|AZV61361.1|2627816_2628056_-|phosphatidylserine-synthase
MELHYGWNELKDIDFMSILPIILPVIAIGMILVLIALIDLYRNRKTRKNVLLWTLIIIFANTIGPILYFVIGRKDSERI
>CP030063.1|AZV61372.1|2638227_2639712_-|argininosuccinate-lyase
MSRLEEFIKNEGSVFPGKTYARELLMPVFNDQRDYLFDAMFDIHRAHVIMLSEQKIIKDEEAKTMLDGIRKVAQTDLAQLTYQPQFEDLFFMMEAKVGEEIGHELAGKIHIGRSRNDMGVAMYRLVLRGHLLQLIGYANQLSEAFLVQAEKHTETYITGYTHTQPAQPTTMGHYFLAIYDVLQRDIGRLWAAYETVNQSPLGAAALTTTGFPISRNRTAELLGFDSVIENSYDSIGGADYLLETATAIMTCMVNAGRWIQDFLQHVTREFGTFHVADPYVQVSSIMPQKRNPVSIEHSRSIASSAYGDALAAMNMIHNTPFGDIVDTEDDLQPHLYRAFSNAGRVMKLMYAVISTLKVNEEHTKKMAAKSSITITELADTLSRDYDISFRKAHSIASHIAKKSIIEGKELYDWDTKEINKTINEFVSVNIAEDEWKKIISPEYFVEIRSIQGGPSPKEVTRMIVNRKQKLEQELQEYKKVVKELNDGRKALVDY
>CP030063.1|AZV61373.1|2639727_2641416_-|iron-ABC-transporter-permease
MIKNRDTRLTVWLLIPVVLVLIAYVLYPSLRTFIESLQKDGTISLGNYQDFFVQESKTNLEALWNSVYISLLSVLVSALVGIPLAFIFNRYDFPGRSFFSSAAILPIVLPSLVGVMAFMFLYGESGLIPNAIKDLFGLDKVPFKIGGVSGILIVHAYTMYVYFYMTVSAAINKIDPSLEEAAYNLGANKLKVFWKVTFPLLTPAIVAASLLVFMISMASFSAPFLLAGGYRVLSLQIYFSKINGDMEIAATQSVILSIVSISFLLFMRWYQNRKDYRMASKGIGAHRSEVKNPVMKWVMVVTGVIGVIILLLPHFTILLLSLVPDGTWTFQTYPTVFNVENYRLLFEDPNIFKPLRNSLLMAVIATLANLVFGVIASYVLVKRKFVGKSFVDILVMIPWALPATVIGMNLIFAFNEPSVFSFGQILVGTFWILPLAYFIRHIPLVVRSTNAVLEQLDDSIEEAARNLGAKWFYTFRRVIFPIIMPGVLSGTLLAFIESVGEFPTSVLLYTISNRPISIEIMNQLRMFNMGQAAAYGMIQITLIVIVLFISNKFFGIKAEKAL
>CP030063.1|AZV61374.1|2641412_2642525_-|spermidine/putrescine-ABC-transporter-ATP-binding-protein
MASIKIENVQKAFGKTIAVDQLNLDIKEGEFFTFLGPSGCGKTTTLRMIAGFYYPTKGVVRFGDKDMTRVPPEKRNTGMVFQNYALFPHMTVFENVAFGLRVRKVSSADLKKRVLDALQKVRLESYSNRQVSQLSGGQQQRVALARALVIEPEILLLDEPLSNLDAKLRDEMRVEILRLQRDYKITTIYVTHDQAEALSMSDRIAVFNYGVCHQVGTPTEIYNRPANDFVASFIGEINLLPVQVEKVQQDNIEIALKNSEKPIKLKVENQARDGISIIQSDADLAVSIRPEAIRILDVTEEGMNIFKGKINSVQFFGSVVNVMVDVQDVLLRVDVFNTHDFGYFYQGKEVYVQLPEKQLRLIPIISGDAP
>CP030063.1|AZV61375.1|2642540_2643620_-|iron-ABC-transporter-substrate-binding-protein
MKNRKKSLVSVLTLSAALLISGCNGTDTKTNSDAGEKGELEDKIVVYSPHGKDILSKFEKQFEDKYGIDVEWLDMGSQEILDRVRSEKSNPQADVWWGAPSTNFNQAKEDGLLAAYKPSYSDSLDEGFRDSEWFWTGTSQTPEVIMYNSKELSKDEVPKDWDELLDPKWKDEIIIRYPLASGTMRTIFSAMIYRTYKDTNDPKEGYDWLKKLDQNTKEYSANPEMMYNKVAKGEGSLSVWAMPDVVMLKENKNYPFEFVIPESGTPVLTEGIAIVEGAKHPKAAEAFYEFVNTPEAAKTLAEEFYRIPTRSDVKGLPEWITETEIKAMDIDWNAFQEKGDEWMKYWDENIKSGDKEIKE
>CP030063.1|AZV61376.1|2643619_2644846_-|ROK-family-transcriptional-regulator
MSFKRTPSHQKYVNKKRIIQCIQECSPISRAEIAVKLQLSKPTVSQAVDELIQEKWVFEKGIGESSSQGGRRPIQLFFNEKAAYIIGVDIGGTKVKIVLSDLSGNIIADTSFSTNTYLNSGLLKQMAIETERLIAKNQIAKERILGMGVGIPGITQTASGLVIEAPSLGWVQYPFIAEAKRYFDFPIFLDNDVNAAALGEQWLGNAQNKRNLLFIAVGTGIGSGIILNNQLYRGASSAAGEMGYMVTDKEDIKREFKPIFHRYGYLESVAGGKSIGGHFTREVLKDPHHFLFERAKSSELSGEDAFLAAKKGDTAAMAVINEAIEHLACGIVNAASLLNPEVIILGGGVLNSAEYILPRIREVVDRYLPSLVEMKTSQLGENAGVLGAVSLFLREHDGILNFRDEGEY
>CP030063.1|AZV61377.1|2645100_2647608_+|hypothetical-protein
MKKALLSLLSLLLVLALLPLGGSAANPDETNVELWNAVKPLETTVTFLNSGAHPDDERSDFLAYLSRGLGVKTSSLIANRGEGGQNEIGDELDNALGIIRSREMIEAAKITGVKAYHLSETTSDPIYDFGFSKTPEETLQKWGEELTYERLIRFIRTYQPDILMPSFQNDDTQHGHHRTMTILSERAFKDAADPTVFPQQLKQGLSVWQVKKLYLPVSSANQATTSIEIGKYDPIYKMTYPQLGEQSRYLHKSQGMGSDIPAAPRQIHLDLKQSAVDTKSESDLFAGVPYNFTDWAEKLPRSASKLKGEFNYLQRNLDAVIEAYPHAKRVFSTSQKALSNVRSITAQVKKAKLSPAIKNDLLHKLSLKEEQLQNVSYVSSGLEVQAEAASKILTKGQNTYVTITMKNNGKQTLKKVAAALNVPKGWTTKSKAKDVNLAPNKSATMTYLVEVPEDAAYYHAYDESTITTSISYKYGSTKTSIKEELDGTIAVLPDVGLTLSPEDIVVNTADVKEEIPVTVTLKNYTEGKASAKVALKVPENWGVHPQNATVSFNEKSEEKQVKFTLRPPKAIQKGEYQVKAAATVNGKSFDSTVQEISYDHIGTFYYQYPAAINTVAFELLKPASLKVGYIESGFDKVADYLSNAGLNITKLTAADLAEGDLSQYDTIVTGIRAYLSREDLKANNARLLEYVENGGHLVVQYHKPGDGWDALKTAPYPLTLGNPSIRWRVTDERATVNVSKPESALFTYPNKITSDDWSNWVQERGLYFPMEWDERYETFISMADPNEEPFDGGILMAKYGNGTYLYTNLVLYRQIQGQVPGGYRIMANLISYGAK
>CP030063.1|AZV61378.1|2647852_2648587_-|amino-acid-ABC-transporter-ATP-binding-protein
MSIITVKNLRKSFGTVEVLKDINAEVQEKEVICVIGPSGSGKSTFLRCLNLLEEVTGGEVVINGHDITDPKRKININKVRQEVGMVFQHFNLFPHKTVLENITLGPIKIRATDKAEAGRLALELLDKVGLKEKANSYPGELSGGQKQRVAIARALAMNPKIMLFDEPTSALDPEMVGDVLEVMKQLAKEGMTMVVVTHEMGFAREVGDRVIFMDGGYIVEENEPNELFGNPQHERTKAFLSKVL
>CP030063.1|AZV61379.1|2648583_2649228_-|amino-acid-ABC-transporter-permease
MDIIVAALPLLLKGLQVTLYIFVIAIILGFLIGLLVALLRLAPIKILNWIAKVYVDAIRGTPFIVQLFFIYFGVNSLNLISLDSTTAGIITVAINAGAYFAEIIRAGIQSIDKGQTEAARSIGFTGAQTMRYVVLPQAFRRMLPTITNQSIISLKDTSLLSVIGIADLTQQGQIQASATFEAFKIWLAVGVIYFIIIYLLTLIANFIERRVQVR
>CP030063.1|AZV61380.1|2649301_2650078_-|glutamine-ABC-transporter-substrate-binding-protein
MKKLGLLSMFLILTIFISACGTNEGKNAGEEKKPEKVYKVGVDTTYPPFEFKEGNDYKGIDIELINAIAKDQDFKIKLSPMDFGGIIPAMQANQLDVAIAGMSITEERKKVVDFSTPYFDAGLTIVVKKDNTSTKTVKDLKGKTIAVKKGTTGAKYAQDNATKLGIKVVQFNDSPAMFQEVANGNADALIEDYPVISYAIAQKDLGLKIVGDRLNGDQYGIAVLKGQNEDLLKKINDGLANLKKDGTYDEIIKTYLGE
>CP030063.1|AZV61381.1|2650597_2651935_-|YjiH-family-protein
MESPSVATNTKQEKPQIQSTTNVLKFIIYSLIGSFMFFIPITINGVSSIPIDHIVTWIKVTLPSAVPIYALIVILLGAVYPFISKSWSKDKVSIVFSLLKVLGAVVAILIYFKIGPEWLMAPSMGPFLFEKLVIPVGLVVPFGALFLALLIGYGLLEFLGVLMQPIMRPIFKTPGRSAVDMVADLAGSYSIGMLITNRLYKEGKYTLKEAAIIATGFSTVSATFMIVVAKTLGLMDLWSLFFWVSLGITYLVTAITVRIWPLNKMSDEYYSDNADPEEVIKEGLFRNAWNSAMVGANNSVSLGRNLWENLKDGFLMTMSILPSILSVGLISLVLAEYTPVFNLLGYLFYPFTWALQIPEPFLAAKASAIGIAEMFLPALLVVDAPLVTKFIIAVVSVSSILFFSATIPCILSTEIPISITKLIVIWFERTLITLIITAPIAILLL

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Crispr_ID: CP030063_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030063_2

3793500-3793611

Orphan

Consensus_repeat	Method
TACTCGTAAGTTTGTGCAGAATACTCGTGA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP030063_2

>merge|CP030063|2|3793500-3793611|CRISPRCasFinder
TAACTGATGGCTTGCGCAGAATACTCGTAAGTTTGTGCAGAATACTCGTGAATTTCGCCCATTTACTGGTGAATTGTGCTTTTACTCGTAAGTTTGTGCAGTATACTCGTGA

>CP030063|2|2|3793500-3793611|CRISPRCasFinder
TAACTGATGGCTTGCGCAGAATACTCGTAA	GTTTGTGCAGAATACTCGTGAATTTCGCCCATTTACTGGTGAATTGTGCTTT
TACTCGTAAGTTTGTGCAGTATACTCGTGA

Protein	Signature genes	Signature genes Name	Protein_function
CP030063.1\|AZV62311.1\|3795257_3796427_+\|aminotransferase	unknown	unknown	gnl\|CDD\|181082
CP030063.1\|AZV62317.1\|3801056_3802403_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP030063.1\|AZV62310.1\|3794760_3795261_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
CP030063.1\|AZV62300.1\|3787238_3787625_-\|kinase	unknown	unknown	gnl\|CDD\|378054
CP030063.1\|AZV62309.1\|3793613_3794456_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP030063.1\|AZV62304.1\|3789436_3790051_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377953
CP030063.1\|AZV62318.1\|3802607_3803012_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370164
CP030063.1\|AZV62299.1\|3786577_3787201_+\|putative-3'-5'-exonuclease-KapD	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236087
CP030063.1\|AZV62307.1\|3791881_3793057_-\|cystathionine-beta-lyase	unknown	unknown	gnl\|CDD\|275146
CP030063.1\|AZV62315.1\|3799308_3799542_-\|DUF378-domain-containing-protein	unknown	unknown	gnl\|CDD\|377214
CP030063.1\|AZV62313.1\|3797079_3798423_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271367
CP030063.1\|AZV62308.1\|3793159_3793420_+\|DUF1871-domain-containing-protein	unknown	unknown	gnl\|CDD\|370210
CP030063.1\|AZV62312.1\|3796585_3796939_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP030063.1\|AZV62306.1\|3791089_3791845_+\|yteA-family-sporulation-protein	unknown	unknown	gnl\|CDD\|274340
CP030063.1\|AZV62305.1\|3790091_3790949_-\|manganese-catalase-family-protein	unknown	unknown	gnl\|CDD\|226076
CP030063.1\|AZV62316.1\|3799745_3800909_+\|NADH-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341466
CP030063.1\|AZV62314.1\|3798767_3799172_+\|general-stress-protein-13	unknown	unknown	gnl\|CDD\|181215
CP030063.1\|AZV62302.1\|3788527_3788752_+\|hypothetical-protein	unknown	unknown	unknown
CP030063.1\|AZV62301.1\|3787743_3788394_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908
CP030063.1\|AZV62303.1\|3788919_3789396_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
CP030063.1\|AZV62311.1\|3795257_3796427_+\|aminotransferase	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
CP030063.1\|AZV62317.1\|3801056_3802403_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP030063.1\|AZV62310.1\|3794760_3795261_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.33042e-25
CP030063.1\|AZV62300.1\|3787238_3787625_-\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	2.87543e-63
CP030063.1\|AZV62309.1\|3793613_3794456_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	9.69634e-38
CP030063.1\|AZV62304.1\|3789436_3790051_+\|hypothetical-protein	gnl\|CDD\|377953	pfam08000, bPH_1, Bacterial PH domain. This family contains many bacterial hypothetical proteins. The structures of Structure 3hsa and Structure 3dcx show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response.	5.08546e-36
CP030063.1\|AZV62318.1\|3802607_3803012_+\|hypothetical-protein	gnl\|CDD\|370164	pfam08868, YugN, YugN-like family. This family of proteins related to B. subtilis YugN are functionally uncharacterized.	3.06089e-66
CP030063.1\|AZV62299.1\|3786577_3787201_+\|putative-3'-5'-exonuclease-KapD	gnl\|CDD\|236087	PRK07748, PRK07748, 3'-5' exonuclease KapD.	1.3457e-124
CP030063.1\|AZV62313.1\|3797079_3798423_-\|hypothetical-protein	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	0
CP030063.1\|AZV62315.1\|3799308_3799542_-\|DUF378-domain-containing-protein	gnl\|CDD\|377214	pfam04070, DUF378, Domain of unknown function (DUF378). Predicted transmembrane domain of unknown function. The majority of the family have two predicted transmembrane regions.	2.3514e-25
CP030063.1\|AZV62307.1\|3791881_3793057_-\|cystathionine-beta-lyase	gnl\|CDD\|275146	TIGR04350, aminotransferase_class_I_and_II, putative C-S lyase. Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).	8.39507e-180
CP030063.1\|AZV62312.1\|3796585_3796939_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.24423e-10
CP030063.1\|AZV62306.1\|3791089_3791845_+\|yteA-family-sporulation-protein	gnl\|CDD\|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	8.15096e-66
CP030063.1\|AZV62305.1\|3790091_3790949_-\|manganese-catalase-family-protein	gnl\|CDD\|226076	COG3546, COG3546, Mn-containing catalase [Inorganic ion transport and metabolism].	2.27819e-91
CP030063.1\|AZV62316.1\|3799745_3800909_+\|NADH-dependent-alcohol-dehydrogenase	gnl\|CDD\|341466	cd08187, BDH, Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. The butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway in anaerobic micro-organism. Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. Activity in the reverse direction is 50-fold lower than that in the forward direction. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Since members of this superfamily use different divalent ions, preferentially iron or zinc, it has been suggested to be renamed to family III metal-dependent polyol dehydrogenases. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3. The active site of YqhD contains a Zn metal, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.	0
CP030063.1\|AZV62314.1\|3798767_3799172_+\|general-stress-protein-13	gnl\|CDD\|181215	PRK08059, PRK08059, general stress protein 13; Validated.	4.50656e-66
CP030063.1\|AZV62308.1\|3793159_3793420_+\|DUF1871-domain-containing-protein	gnl\|CDD\|370210	pfam08958, DUF1871, Domain of unknown function (DUF1871). This set of hypothetical proteins is produced by prokaryotes pertaining to the Bacillus genus.	5.76982e-27
CP030063.1\|AZV62301.1\|3787743_3788394_+\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	1.07221e-72
CP030063.1\|AZV62303.1\|3788919_3789396_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.88013e-12

>CP030063.1|AZV62308.1|3793159_3793420_+|DUF1871-domain-containing-protein
MDTQQMNFALVAVLQEWDPFKIGWDLYEPEIADTVVAIRDIDDPKELAEKIKSIYEFAFDESIQMEKCLDVARKLLIIKNDASCSI
>CP030063.1|AZV62307.1|3791881_3793057_-|cystathionine-beta-lyase
MNKSIFEEQINRENSGSAKWDKNSLTSLYGREDVLPMWVADMDFPSPEGIQKALMERLNHPIFGYTVPSETVFTEIQSWLKDRHSWQIDKKWISFSSGVVSAIGTTIQAFTNPGDKILLQSPVYTPFFDMIKNNDREVVNSRLIIEKDRFEIDFNDFEDKLKSGVKLFLFCSPHNPGGRVWTKDELLRIGELCEKYDVVIVSDEIHADLFHTTSKHYPIGSLSEKLADRTVTLMAPSKTFNIAGLQASFLITSNERLQKKLQMAQTKLAFHGLNIFALTAMEAAYREGLEWLEDMIGYIEENIKVAEEFIAAEIPSLHVMHPEASYLLWIDCRDLGLTDKEIKDRLIHQGKLALEPGSKYGPGGEGFVRMNLGCSRSVLLDGLNRLKLAFS
>CP030063.1|AZV62306.1|3791089_3791845_+|yteA-family-sporulation-protein
MLSNQQLKEFQQQLQQTKQELEERLNDSGNHDLRRSLEDSTGELSSYDNHPGDEGTELYEREKDLALSEHDRDEIRDIERALSAIEAGEYGKCEVCSKEIPLERLKAIPTTTYCVEHTPSQETSGNRPVEEEVLGPPFGRFDYDDRHESVAYDAEDSWQDVASYGTSESPSDFVNPPNDYEDMYVESEENVGYVENYENFVGVDIYGKEVTVYKNSQYEELKEELFEENIQTPFGDLPRYEHDPYVDEEKD
>CP030063.1|AZV62305.1|3790091_3790949_-|manganese-catalase-family-protein
MYFYKEDLINMIVPDKPDPNAAKVLQETLGGQFGEMRTMMQYSFQSANFRGKAKQYRDLIRGVFLEELSHVELVQSTINQLLNGAGGDMPGDSGIDGAPLDEVIKGGANPHHFIVGAKASLPVDAGGNPWNGSWVYDHGNLVANLLNNVMLESTGVLQKSRIYEMSSNKTMRETLAFLMVRDNSHQNAFAKALETLGVDWGKIFPVPNYDLNKYPECRKYVDLGYHNAQFNFRMDQTRISQIFQGETPSRNGGNLAVTEPPKGFPVPEMPDMPNEHSPGLSDLNN
>CP030063.1|AZV62304.1|3789436_3790051_+|hypothetical-protein
MFKKMAADALGLSDIGSVISPADYDKVDADDYIMHEDGEKIYFLIKSKTDEYCFTNQAFIHLDGTSAISKKRTLTRYSYSQYTISNATLETAGTVDLDAEIKFSIGAKTFSIDVHKKFIEELKDLFKSLVKISEICHENEFALQYAQQSVNLASSTLNQVRTDGSQMAASFKEINSAAFEWLMDSRKKYHVKDFGFVFEKYINN
>CP030063.1|AZV62303.1|3788919_3789396_+|GNAT-family-N-acetyltransferase
MQIVAKRMIAADTVKDFFIQHWETTQVVFSRGSFHYAELEGVGVMDENGKITGLGTYKLSDHVCQIISLNSEHENQGVGSSLLYVMENIAKEKNCHTIKAITTNDNLQALKFFQKRGYVISEIVKNAVEESRKIKPEIPFYSFDGIPIRDEIILEKCL
>CP030063.1|AZV62302.1|3788527_3788752_+|hypothetical-protein
MDFLNHALLGLFLYFPEDKTEYISAGITCFIFLVAAVFTMRAIIRYSKKEELKTKQFEDEVTRRNQRIKDDTIS
>CP030063.1|AZV62301.1|3787743_3788394_+|peptidylprolyl-isomerase
MKMKNGVSSHFILKRKRLCTMTNFPQLTSEVLENEKAVIMQTTMGDIKIKLFPELAPKTVENFLTHAENGYYEGIIFHRVIKDFMLQGGDPTGTGMGGESIWGAPFEDEFSMQLFNLRGALSMANAGPGTNGSQFFVVQAQHVDSRMGEQMKQAGYPEEIISAYMEQGGTPWLDHKHSVFGQVVEGMDVVDTIANVETVTGDKPAVDVVIKGITIL
>CP030063.1|AZV62300.1|3787238_3787625_-|kinase
MSEQDFKIGDKVTAIYKTGKYIGEVTDIRPAAYLVKVLAVLKHPMQGDLHNPKQTEVSMFHQRRALAFREQTNVPKNMVRTFDEEIPEYKESLREAVEKMKGTLSGAQTEWNDKSLQLLEDLAADYFK
>CP030063.1|AZV62299.1|3786577_3787201_+|putative-3'-5'-exonuclease-KapD
MEEQQQYVFIDFEFTMPEGKANPTGFYPEIIEVGLVTVINETIEEQFSSFVNPLKFPVLTGRCKKFLNITQDQVDRGISFEELVALLKKIDEQHPTTIVTWGNMDMKVLRQNCQKAGLDFPFSGKENDLCLEYKRFFGDQNQTGLWKAVQAYGKEGTGKHHRALDDAITTYNIFKLVEKDKSYMKNHEPTTIGDRIDLSKVLNHLAL
>CP030063.1|AZV62309.1|3793613_3794456_-|alpha/beta-hydrolase
MESHTIKGLERVGNIEIYFEYDRIDDSLPTLVLLHGFLSSSFSFRKLVPHLIKEYNVISIDLPPFGQSGKYYRYTYSFRNIAKSVVMFLEGKGIRKFSIIGHSMGGQISLQLIKSYPDLVDHAILLAGSGYQPGYSEKMKMVSYLPFFSYGIKRYLQKSGIEKNLKNVVHDPAMIDDEMRQGYLGPFIKKHDIFRALGRMLRDKEIDLLKEDLSDIHTPCLLIWGRHDRVVPLNIGERLHDDLPNSELVVIEDSGHLLPEEKPEEVYQLIKGFIGVATPT
>CP030063.1|AZV62310.1|3794760_3795261_+|Lrp/AsnC-family-transcriptional-regulator
MHLNEEELEVLRIIENNSRIDLKDLAKMTDQSDSDIEITLKKLEDMRVIVRYLTVINWAKVDEYHGVTAMIDVKVTPKRGVGFDDVAKRIYKFKEVESVYLMSGAYDLSVIVEGRSMNEVASFVSEKLSTLDSVISTTTHFIMKKYKHDGTIFDQTEEDKRIVVSP
>CP030063.1|AZV62311.1|3795257_3796427_+|aminotransferase
MIKTSYVSKTIAELKPSGIRRFFDLAANLEGVVSLGVGEPDFVTSWAVREAAINSLEEGYTSYTANAGLFELRSEISRYMEKQFHVSYRPDDQIIVTVGASQALDIALRTILNPGEEVIVVEPCFVAYAPLVTMAGGIPVTVQTSKEEDFKLTPQQLEAAITPKTKAVLICSPNNPTGTQLGQEELVMLADIVKKHDLLVISDEIYAELAYDEEFTSFAAVDGMLERTIVINGFSKGFAMTGWRLGFVCAPKEISEAMLKLHQYAMMCAPTVAQHAALEALKNGMQDVEEMRRSYRRRRNYIVKSFNDMGLDCHNPGGAFYAFPSIERTGMTSMEFAEKLLTEELVAVVPGDVFGESGEGHIRCSYASSMEQLQEALRRMERFMKNHCQ
>CP030063.1|AZV62312.1|3796585_3796939_-|XRE-family-transcriptional-regulator
MSNIAKNIRQYREDHNLTQQELALKLRIGTKKIEKYESGESVPDTQTILRLSTVLDIPASEFLKDAQTGNAAGIDEDIKKLIEEIGTKKAELILRTAKDFSEEQILKVMHTLYNTQA
>CP030063.1|AZV62313.1|3797079_3798423_-|hypothetical-protein
MSKQDQWTSKLGFILAAAGSAIGLGAIWKLPYMTGENGGGVFFLLFIIFTLLIGAPILIAEFTIGRNAQKDAISAYKHIAPGKPWALIGYGGVVASIILLSFFSVVGGWIISYLARSFTGSLSNLTQEEYGNFFNTIISNPYETVIAQLLFMVFTIWVVQGGVSKGIEKANKYMMPSLFILFIILLIRSLTLDGAMEGVKFFLKPDFSALTGETILLALGQSFFALSVGVSVMVTYASYLSKKEDITKSAFSVVGLNIFISLLAGLVIFPAVFALGFSPSSGPGLVFVVLPAVFNEMALGGIFMFIFFVLLLFATLTTAFSILEIVVAAMIKGDSAKRKKASWIAGITVFLIGIPSALSFGVLSDVKIFNLSIFDFADYLTSNIALPVGALFISLFIGYQMKRIEVQKEFETGADPGRSLFKLWYFLIRYIVPIMIILVFLKSTNLI
>CP030063.1|AZV62314.1|3798767_3799172_+|general-stress-protein-13
MSEKFEIGAVVAGKVTGIQPYGAFVALDESTQGLVHISEITHGFVKDINEHLKVGDEVKVKVLSIDSAAGKIGLSIRATEEAPERTEAPKKAPKKRQASVKATSHIESTEGFNTLKDKLQEWIEQSQREDLIKK
>CP030063.1|AZV62315.1|3799308_3799542_-|DUF378-domain-containing-protein
MSGIQRIALVLTIIGAINWGLIGFFQFDLVASIFGGQDAGMARIVYGLVGIAGLINLGLLFKPSPEISREPETKPTR
>CP030063.1|AZV62316.1|3799745_3800909_+|NADH-dependent-alcohol-dehydrogenase
MENFTYKNPTKVIFGKGQLESLKTEIPAYGDRVLLVYGGGSIKKNGLYEKVINALKEIDAEVHELSGVEPNPRISTVRKGVDLCKEHGIDFVLAVGGGSVIDATKAIVAGAKYVGDPWDLVIKKAPVEEALPFGTVLTLAATGSEANSGSVITNWETKEKYGWGSPLVFPQFSILDPENTFSVPKDQTVYGMVDMMSHVFETYFHPETHAPLQDRFCESLLSTVIETAPKLLEDLEDYEHRATILYAGNLALNGSLGVGYSGDWATHNIEHAVSAVYDIPHAGGLAILFPNWMKHVLHENVARFKQVAVRVFHVDPEGKSDEEAALEGIERLRSFWSSLGAPTNLSDYGIDDSQLEVMADKAMSRGEFGRFKVLNREDVLAILRASL
>CP030063.1|AZV62317.1|3801056_3802403_+|glucose-6-phosphate-isomerase
MAHIRFDYSKALPFFGEHEITYLQDAVKVAHHSLHEQTGAGNEYLGWLDLPANYDKEEFSRIKKAAAKIKEDSEVLLVIGIGGSYLGARAAVEMLQHSFYNILPSDKRKAPQILFVGNNISSTYMQDVMDLLENRDFSINVISKSGTTTEPALAFRIFRKLLEQKYGVEEAKSRIYATTDKEKGALKTVATEEGFQTFVIPDDVGGRYSVLTAVGLLPIAVSGADIDQIMEGAERARVDFSSSELGENQAYQYAAVRNILYNKGKTIEMLINYEPGLQYFSEWWKQLFGESEGKDQKGIFPSSANFSTDLHSLGQYVQEGRRDLFETVIKVDKARHEILIEEAANDLDGLNYLAGETVQFVNNKAFEGTLLAHTDGGVPNLIVTVPQLDAYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKVNMFALLGKPGYEKKKAELEQRL
>CP030063.1|AZV62318.1|3802607_3803012_+|hypothetical-protein
MIKISSELEGKTFGLFDLETKLKPEGYAIGGGWDYDHGSFDYKIDDSDGYQFLRVPFKAVDGSLDQDGVMVELLQPFLLSHKYEDGIDGEGNIGNLSASFNQFAEPENPDAEFPENYISLGKTLVRDLEKLLLH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

293833 : 298091

Streptomyces_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZV63820.1\|293833_294796_+	alcohol dehydrogenase	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	1.7e-26	30.5
AZV59404.1\|295103_295424_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	4.4e-16	40.4
AZV59405.1\|295704_296145_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	6.2e-37	54.9
AZV59406.1\|296371_296692_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	5.7e-16	40.4
AZV59407.1\|296779_297100_+	thioredoxin	A0A2I2L415	Orpheovirus	8.8e-09	34.5
AZV59408.1\|297158_298091_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.3e-89	55.4

DBSCAN-SWA_2

1410280 : 1456868

Paenibacillus_phage(100.0%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZV60349.1\|1410280_1411439_+\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	2.0e-34	40.6
AZV60350.1\|1411692_1412262_+	hypothetical protein	NA	NA	NA	NA
AZV60351.1\|1413274_1414696_-	D-xylose transporter XylE	NA	NA	NA	NA
AZV60352.1\|1415982_1417485_-	xylulokinase	NA	NA	NA	NA
AZV60353.1\|1417543_1418881_-	xylose isomerase	NA	NA	NA	NA
AZV60354.1\|1419143_1420265_+	ROK family transcriptional regulator	NA	NA	NA	NA
AZV60355.1\|1420792_1421200_+	DoxX family protein	NA	NA	NA	NA
AZV60356.1\|1421358_1422009_-	class D sortase	NA	NA	NA	NA
AZV60357.1\|1422010_1423429_-	processed acidic surface protein	NA	NA	NA	NA
AZV60358.1\|1425152_1427528_-	hypothetical protein	NA	NA	NA	NA
AZV60359.1\|1428927_1429356_+	MarR family transcriptional regulator	NA	NA	NA	NA
AZV60360.1\|1429405_1430047_+	nitroreductase family protein	NA	NA	NA	NA
AZV60361.1\|1430135_1430429_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
AZV63887.1\|1430748_1430973_-	hypothetical protein	NA	NA	NA	NA
AZV60362.1\|1431058_1431346_+	hypothetical protein	NA	NA	NA	NA
AZV60363.1\|1431498_1431696_-	hypothetical protein	NA	NA	NA	NA
AZV60364.1\|1431994_1432411_+	hypothetical protein	NA	NA	NA	NA
AZV60365.1\|1432575_1433091_-	hypothetical protein	NA	NA	NA	NA
AZV60366.1\|1433275_1434370_+	hypothetical protein	NA	NA	NA	NA
AZV60367.1\|1434619_1434979_-	hypothetical protein	NA	NA	NA	NA
AZV60368.1\|1435421_1436657_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AZV60369.1\|1436791_1437463_-	nucleosidase	NA	NA	NA	NA
AZV60370.1\|1437630_1438365_-	3-ketoacyl-ACP reductase	NA	NA	NA	NA
AZV60371.1\|1438707_1439943_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AZV60372.1\|1440274_1440784_-	DinB family protein	NA	NA	NA	NA
AZV60373.1\|1442720_1443587_+	phenazine biosynthesis protein	NA	NA	NA	NA
AZV60374.1\|1443843_1444665_+	anti-anti-sigma factor	NA	NA	NA	NA
AZV60375.1\|1445151_1446387_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AZV60376.1\|1446571_1446811_-	hypothetical protein	NA	NA	NA	NA
AZV60377.1\|1447194_1447374_-	hypothetical protein	NA	NA	NA	NA
AZV60378.1\|1447564_1448434_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZV60379.1\|1448562_1449102_+\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
AZV60380.1\|1449262_1450156_+	EamA/RhaT family transporter	NA	NA	NA	NA
AZV60381.1\|1450434_1450842_-	hypothetical protein	NA	NA	NA	NA
AZV60382.1\|1451033_1451390_-	hypothetical protein	NA	NA	NA	NA
AZV60383.1\|1451873_1452962_-	polysaccharide deacetylase	NA	NA	NA	NA
AZV60384.1\|1453412_1454117_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AZV60385.1\|1454206_1454932_+	MerR family transcriptional regulator	NA	NA	NA	NA
AZV60386.1\|1455632_1456868_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2855786 : 2864077

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZV61563.1\|2855786_2856362_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.8e-28	37.7
AZV61564.1\|2856361_2857387_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	3.9e-66	44.6
AZV61565.1\|2857429_2858845_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.2e-54	34.0
AZV61566.1\|2858829_2861049_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.2e-165	42.7
AZV61567.1\|2861032_2861719_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AZV61568.1\|2861715_2861970_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AZV61569.1\|2861962_2862682_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	1.5e-48	44.3
AZV61570.1\|2862784_2864077_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	5.0e-18	24.4

DBSCAN-SWA_4

4954072 : 5004324

Enterococcus_phage(20.0%)

coat,transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZV63330.1\|4954072_4955341_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.3e-148	65.2
AZV63331.1\|4955423_4956771_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.7e-90	59.9
AZV63332.1\|4956790_4957027_+	hypothetical protein	NA	NA	NA	NA
AZV63333.1\|4957353_4959024_+\|protease	ATP-dependent protease LonB	A0A1V0DYC6	Dinoroseobacter_phage	5.1e-07	22.4
AZV63334.1\|4959268_4961590_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	6.3e-181	44.3
AZV63335.1\|4961586_4962168_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
AZV63336.1\|4962223_4962706_-	hypothetical protein	NA	NA	NA	NA
AZV63337.1\|4962959_4964306_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
AZV63338.1\|4964316_4965147_+	cytochrome C assembly protein	NA	NA	NA	NA
AZV63339.1\|4965156_4966089_+	hydroxymethylbilane synthase	NA	NA	NA	NA
AZV63340.1\|4966088_4966886_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
AZV63341.1\|4966882_4967875_+	porphobilinogen synthase	NA	NA	NA	NA
AZV63342.1\|4967913_4969203_+	glutamate-1-semialdehyde-2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	3.8e-10	26.5
AZV63343.1\|4969592_4971017_+	hypothetical protein	NA	NA	NA	NA
AZV64156.1\|4971184_4972183_+\|coat	spore coat protein YsxE	NA	NA	NA	NA
AZV63344.1\|4972240_4972432_-	hypothetical protein	NA	NA	NA	NA
AZV63345.1\|4972685_4972928_+	hypothetical protein	NA	NA	NA	NA
AZV63346.1\|4972929_4975581_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.8e-160	42.6
AZV63347.1\|4975637_4976483_-	hypothetical protein	NA	NA	NA	NA
AZV63348.1\|4976451_4977393_-	RimK family alpha-L-glutamate ligase	A0A1D7SA11	Synechococcus_phage	1.9e-30	35.9
AZV63349.1\|4977491_4978781_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
AZV63350.1\|4979624_4980377_+	prepilin peptidase	NA	NA	NA	NA
AZV63351.1\|4980660_4981659_+	hypothetical protein	NA	NA	NA	NA
AZV63352.1\|4981850_4982420_+	septum formation inhibitor Maf	NA	NA	NA	NA
AZV64157.1\|4982479_4983154_+	JAB domain-containing protein	NA	NA	NA	NA
AZV63353.1\|4983302_4984322_+	rod shape-determining protein	NA	NA	NA	NA
AZV63354.1\|4984459_4985332_+	rod shape-determining protein MreC	NA	NA	NA	NA
AZV63355.1\|4985328_4985847_+	rod shape-determining protein MreD	NA	NA	NA	NA
AZV63356.1\|4985964_4986648_+	septum site-determining protein MinC	NA	NA	NA	NA
AZV63357.1\|4986650_4987454_+	septum site-determining protein MinD	F0PIG8	Enterococcus_phage	2.3e-05	26.1
AZV63358.1\|4987586_4988030_-	RNA-binding protein S1	NA	NA	NA	NA
AZV63359.1\|4988286_4989036_+	M23 family peptidase	NA	NA	NA	NA
AZV63360.1\|4989028_4989895_+	stage IV sporulation protein FB	NA	NA	NA	NA
AZV63361.1\|4989934_4991410_+	ribonuclease E/G	NA	NA	NA	NA
AZV63362.1\|4991582_4991891_+	50S ribosomal protein L21	NA	NA	NA	NA
AZV63363.1\|4991904_4992237_+\|protease	ribosomal-processing cysteine protease Prp	D2J003	Enterococcus_phage	9.5e-06	35.8
AZV63364.1\|4992249_4992540_+	50S ribosomal protein L27	NA	NA	NA	NA
AZV63365.1\|4993077_4993617_+	sporulation protein	NA	NA	NA	NA
AZV63366.1\|4993665_4994955_+	GTPase ObgE	NA	NA	NA	NA
AZV63367.1\|4994995_4995445_+	ACT domain-containing protein	NA	NA	NA	NA
AZV63368.1\|4995790_4996666_+	prephenate dehydratase	NA	NA	NA	NA
AZV63369.1\|4997734_4998265_-	transcription repressor NadR	NA	NA	NA	NA
AZV63370.1\|4998314_4999442_-	cysteine desulfurase	H7BUW1	unidentified_phage	4.6e-28	35.2
AZV63371.1\|4999545_5001129_+	L-aspartate oxidase	NA	NA	NA	NA
AZV63372.1\|5001109_5001961_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
AZV63373.1\|5001957_5003064_+	quinolinate synthase	NA	NA	NA	NA
AZV63374.1\|5003478_5004324_-\|protease	metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP030063

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection