CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP034786	Escherichia coli strain ECZP248 plasmid pTB402, complete sequence	0 crisprs	RT	0	2
CP034784	Escherichia coli strain ECZP248 chromosome, complete genome	8 crisprs	csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas1,cas2,cas3,cas14j,DEDDh,c2c9_V-U4,DinG	12	5
CP034785	Escherichia coli strain ECZP248 plasmid pTBMCR401, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1987 : 15851

Escherichia_phage(76.92%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZW02406.1\|1987_5104_-	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	5.8e-28	24.2
AZW02493.1\|6459_8016_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.2e-105	43.1
AZW02407.1\|8198_8420_+	type II toxin-antitoxin system Phd/YefM family antitoxin	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
AZW02408.1\|8419_8800_+	type II toxin-antitoxin system death-on-curing family toxin	Q71T66	Escherichia_phage	4.1e-61	96.8
AZW02409.1\|8804_8984_+	PdcA protein	Q71TH5	Escherichia_phage	1.5e-21	93.2
AZW02410.1\|9011_10055_+	DUF968 domain-containing protein	A0A077SLM1	Escherichia_phage	2.0e-203	98.0
AZW02411.1\|11084_11306_+	host cell division inhibitor Icd-like protein	Q38557	Escherichia_phage	6.0e-25	81.2
AZW02412.1\|12453_13305_-	hypothetical protein	A0A077SLM8	Escherichia_phage	6.1e-158	99.6
AZW02413.1\|13415_13625_-	c1 repressor inactivator	A0A077SK26	Escherichia_phage	9.1e-31	98.6
AZW02414.1\|13590_13686_-	peptidase	Q38402	Escherichia_phage	2.8e-11	100.0
AZW02415.1\|13704_13818_-	peptidase	Q5XLQ7	Enterobacteria_phage	3.2e-14	100.0
AZW02416.1\|14229_14451_+	creatininase	Q38403	Escherichia_phage	2.6e-36	100.0
AZW02417.1\|15539_15851_+	lysogeny establishment protein	Q71TG4	Escherichia_phage	8.8e-46	96.1

DBSCAN-SWA_2

24637 : 83762

Escherichia_phage(42.11%)

integrase,transposase

attL 19287:19346|attR 33062:35252

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
19287:19346	attL	NA	NA	NA	NA
AZW02426.1\|24637_24814_+	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
AZW02427.1\|25803_26508_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AZW02428.1\|26709_27498_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
AZW02494.1\|27628_28102_-	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
AZW02429.1\|28259_29273_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AZW02495.1\|29475_29826_+	DUF3330 domain-containing protein	NA	NA	NA	NA
AZW02430.1\|30001_30562_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
AZW02431.1\|30565_31162_+	DUF4158 domain-containing protein	A0A1B0V7H9	Salmonella_phage	4.7e-64	85.1
AZW02432.1\|31193_31871_-	TetR family transcriptional regulator	NA	NA	NA	NA
AZW02433.1\|31949_33149_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
AZW02434.1\|33415_33721_-	LysR family transcriptional regulator	NA	NA	NA	NA
AZW02435.1\|33748_34963_-	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	5.5e-19	28.7
AZW02436.1\|35179_36064_-	DUF3363 domain-containing protein	NA	NA	NA	NA
33062:35252	attR	NA	NA	NA	NA
AZW02437.1\|36094_37588_-\|transposase	IS91 family transposase	NA	NA	NA	NA
AZW02438.1\|37798_38068_-	hypothetical protein	NA	NA	NA	NA
AZW02439.1\|38018_38756_-	resolvase	NA	NA	NA	NA
AZW02440.1\|38862_39354_+	hypothetical protein	NA	NA	NA	NA
AZW02441.1\|39387_40092_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AZW02496.1\|40062_40407_+	hypothetical protein	A0A1B0VAH3	Salmonella_phage	2.4e-36	100.0
AZW02442.1\|40974_41964_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZW02443.1\|41979_42756_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
AZW02444.1\|42974_43361_+	recombination enhancement function domain protein	Q71TG3	Escherichia_phage	9.5e-58	95.5
AZW02497.1\|43550_44195_+	maturation control protein	A0A1B0VAG4	Salmonella_phage	1.7e-96	86.3
AZW02445.1\|44248_44938_-	EAL domain-containing protein	NA	NA	NA	NA
AZW02446.1\|45932_46181_-	modulator protein	Q71TG0	Escherichia_phage	6.8e-41	98.8
AZW02447.1\|46650_50535_-	helicase	A0A077SK04	Escherichia_phage	0.0e+00	96.3
AZW02448.1\|50763_50895_-	replication protein RepA4	NA	NA	NA	NA
AZW02449.1\|51147_51399_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
AZW02450.1\|51395_51683_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	4.5e-20	50.5
AZW02451.1\|51972_52173_-	DUF839 domain-containing protein	NA	NA	NA	NA
AZW02452.1\|52542_56040_-	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	3.5e-98	34.8
AZW02453.1\|57547_57997_-	hypothetical protein	NA	NA	NA	NA
AZW02454.1\|57986_59033_-	thioredoxin family protein	NA	NA	NA	NA
AZW02455.1\|64599_64794_+	hypothetical protein	NA	NA	NA	NA
AZW02456.1\|65198_66071_+	hypothetical protein	NA	NA	NA	NA
AZW02457.1\|67034_67769_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AZW02458.1\|67912_69185_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.0e-169	95.3
AZW02459.1\|70503_73977_-	cellulose biosynthesis protein BcsC	NA	NA	NA	NA
AZW02460.1\|75015_76362_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.6e-25	29.3
AZW02461.1\|77105_79256_-	cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB	NA	NA	NA	NA
AZW02462.1\|79319_81425_-	UDP-forming cellulose synthase catalytic subunit	NA	NA	NA	NA
AZW02463.1\|82819_83167_+	hypothetical protein	A0A2L1IVA1	Escherichia_phage	4.3e-09	88.6
AZW02464.1\|83057_83762_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	4.0e-139	99.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP034784

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CRISPR-Cas detection and classification

Crispr_ID: CP034784_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_1

958264-958841

Orphan

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

9 spacers

The CRISPR arrays of CP034784_1

>merge|CP034784|1|958264-958841|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGTGTCGGACACCATAATGATACTAAGTGTCGGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTGTCGGACACCATAATGATACTAAGTGTCGGAGTGTTCCCCGCGCCAGCGGGGATAAACCGATCGGTAACTACGGCACAAAACAGGAGCACAGGTGTTCCCCGCGCCAGCGGGGATAAACCGTTTTGTGATTCAGTAATCGTTTGAGTATGTACGTGTTCCCCGCGCCAGCGGGGATAAACCGCGAATCCCAGCCTTGAAATTTTGGCTCATGGAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGCTGACGCGGTAAAAAGCGGGGCGTGATTCGGTGTTCCCCGCGCCAGCGGGGATAAACCGAGCAGATACACGGCTTTGTATTCCGTGCGCCCGTGTTCCCCGCGCCAGCGGGGATAAACCGAATAGCAATAGTCCATAGATTTGCGAAAACAGGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACCA

>CP034784|1|1|958264-958780|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTCGGACACCATAATGATACTAAGTGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTCGGACACCATAATGATACTAAGTGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCGGTAACTACGGCACAAAACAGGAGCACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGTGATTCAGTAATCGTTTGAGTATGTAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCCCAGCCTTGAAATTTTGGCTCATGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCTGACGCGGTAAAAAGCGGGGCGTGATTCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP034784|1|1|958264-958841|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTCGGACACCATAATGATACTAAGTGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTCGGACACCATAATGATACTAAGTGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCGGTAACTACGGCACAAAACAGGAGCACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGTGATTCAGTAATCGTTTGAGTATGTAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCCCAGCCTTGAAATTTTGGCTCATGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCTGACGCGGTAAAAAGCGGGGCGTGATTCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>CP034784|1|1|958264-958841|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTCGGACACCATAATGATACTAAGTGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGTCGGACACCATAATGATACTAAGTGTCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCGGTAACTACGGCACAAAACAGGAGCACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGTGATTCAGTAATCGTTTGAGTATGTAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCCCAGCCTTGAAATTTTGGCTCATGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCTGACGCGGTAAAAAGCGGGGCGTGATTCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZV99069.1\|970950_972750_+\|assimilatory-sulfite-reductase-(NADPH)-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
CP034784.1\|AZV99061.1\|957252_957924_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
CP034784.1\|AZV99054.1\|949019_951254_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
CP034784.1\|AZV99052.1\|944857_947614_-\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
CP034784.1\|AZV99053.1\|947670_948972_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
CP034784.1\|AZV99064.1\|966294_967074_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
CP034784.1\|AZV99062.1\|959478_960957_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
CP034784.1\|AZV99070.1\|972749_974462_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
CP034784.1\|AZV99068.1\|970269_970635_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP034784.1\|AZV99066.1\|968669_968930_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
CP034784.1\|AZV99067.1\|968920_970192_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
CP034784.1\|AZV99060.1\|956973_957114_-\|hypothetical-protein	unknown	unknown	unknown
CP034784.1\|AZV99059.1\|954729_956028_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
CP034784.1\|AZV99058.1\|953004_954642_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
CP034784.1\|AZV99055.1\|951331_951580_+\|MazF-MazE-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
CP034784.1\|AZW02061.1\|962578_963364_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
CP034784.1\|AZV99065.1\|967070_967931_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
CP034784.1\|AZV99057.1\|951985_952777_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
CP034784.1\|AZV99056.1\|951579_951915_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
CP034784.1\|AZV99063.1\|960983_962261_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZV99069.1\|970950_972750_+\|assimilatory-sulfite-reductase-(NADPH)-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP034784.1\|AZV99061.1\|957252_957924_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
CP034784.1\|AZV99054.1\|949019_951254_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
CP034784.1\|AZV99066.1\|968669_968930_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	7.43419e-42
CP034784.1\|AZV99053.1\|947670_948972_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
CP034784.1\|AZV99064.1\|966294_967074_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
CP034784.1\|AZV99062.1\|959478_960957_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	3.68061e-108
CP034784.1\|AZV99070.1\|972749_974462_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP034784.1\|AZV99068.1\|970269_970635_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
CP034784.1\|AZV99067.1\|968920_970192_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	9.16926e-127
CP034784.1\|AZV99052.1\|944857_947614_-\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
CP034784.1\|AZV99059.1\|954729_956028_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP034784.1\|AZV99058.1\|953004_954642_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP034784.1\|AZV99055.1\|951331_951580_+\|MazF-MazE-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	2.43005e-47
CP034784.1\|AZW02061.1\|962578_963364_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.78752e-139
CP034784.1\|AZV99065.1\|967070_967931_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.74927e-89
CP034784.1\|AZV99057.1\|951985_952777_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
CP034784.1\|AZV99056.1\|951579_951915_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
CP034784.1\|AZV99063.1\|960983_962261_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.37725e-29

>CP034784.1|AZV99061.1|957252_957924_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>CP034784.1|AZV99060.1|956973_957114_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNEYKITDAAVNLFIQI
>CP034784.1|AZV99059.1|954729_956028_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP034784.1|AZV99058.1|953004_954642_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>CP034784.1|AZV99057.1|951985_952777_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>CP034784.1|AZV99056.1|951579_951915_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>CP034784.1|AZV99055.1|951331_951580_+|MazF-MazE-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPTTLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>CP034784.1|AZV99054.1|949019_951254_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>CP034784.1|AZV99053.1|947670_948972_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDLNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>CP034784.1|AZV99052.1|944857_947614_-|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG
>CP034784.1|AZV99062.1|959478_960957_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWSVDYKSWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEINHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDNMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>CP034784.1|AZV99063.1|960983_962261_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVTASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLTLTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAVEAYRNMWLMGMAALVMVIVFTFLLFQKIRTADSAPAMASSK
>CP034784.1|AZW02061.1|962578_963364_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVFDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>CP034784.1|AZV99064.1|966294_967074_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>CP034784.1|AZV99065.1|967070_967931_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAENLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>CP034784.1|AZV99066.1|968669_968930_-|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTAERLINACPAGLFSLTPEGNLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>CP034784.1|AZV99067.1|968920_970192_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEEEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL
>CP034784.1|AZV99068.1|970269_970635_-|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>CP034784.1|AZV99069.1|970950_972750_+|assimilatory-sulfite-reductase-(NADPH)-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQVASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>CP034784.1|AZV99070.1|972749_974462_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWIKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD

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Crispr_ID: CP034784_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_2

985885-986340

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

7 spacers

cas2,cas1,cas5,cas7,cse2gr11,cas8e

The CRISPR arrays of CP034784_2

>merge|CP034784|2|985885-986340|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGAGCGTAGAGATTCTCGAAACCGATCCGGACGGTGTTCCCCGCGCCAGCGGGGATAAACCGAATAAATAATAATCCAGTAGCCCCATGTATTAGTGTTCCCCGCGCCAGCGGGGATAAACCGGTAATAAAAAATATTCTATTTCTGCTGAATCAGTGTTCCCCGCGCCAGCGGGGATAAACCGCTTGCGAGCAAAAGATCCAGGCCGAGAAAGACGTGTTCCCCGCGCCAGCGGGGATAAACCGCGATAACCGCGTCAGTATTGGACAGGATATCAGTGTTCCCCGCGCCAGCGGGGATAAACCGGGTAAAAACACGGTCTGAACCGACATTCATGTGTGTTCCCCGCGTCAGCGGGGATAAACCGGGCGCACTGGATGCGATGATGGATATCACTTGGAGTTCCCCGCCCCTGCGGTAGAACTCCC

>CP034784|2|2|985885-986279|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCGTAGAGATTCTCGAAACCGATCCGGACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAAATAATAATCCAGTAGCCCCATGTATTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAATAAAAAATATTCTATTTCTGCTGAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTTGCGAGCAAAAGATCCAGGCCGAGAAAGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGATAACCGCGTCAGTATTGGACAGGATATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGTAAAAACACGGTCTGAACCGACATTCATGT
GTGTTCCCCGCGTCAGCGGGGATAAACCG

>CP034784|2|2|985885-986279|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCGTAGAGATTCTCGAAACCGATCCGGACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAAATAATAATCCAGTAGCCCCATGTATTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAATAAAAAATATTCTATTTCTGCTGAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTTGCGAGCAAAAGATCCAGGCCGAGAAAGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGATAACCGCGTCAGTATTGGACAGGATATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGTAAAAACACGGTCTGAACCGACATTCATGT
GTGTTCCCCGCGTCAGCGGGGATAAACCG

>CP034784|2|2|985885-986340|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCGTAGAGATTCTCGAAACCGATCCGGACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATAAATAATAATCCAGTAGCCCCATGTATTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAATAAAAAATATTCTATTTCTGCTGAATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTTGCGAGCAAAAGATCCAGGCCGAGAAAGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGATAACCGCGTCAGTATTGGACAGGATATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGTAAAAACACGGTCTGAACCGACATTCATGT
GTGTTCCCCGCGTCAGCGGGGATAAACCG	GGCGCACTGGATGCGATGATGGATATCACTTG
GAGTTCCCCGCCCCTGCGGTAGAACTCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZV99084.1\|990641_990965_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
CP034784.1\|AZV99089.1\|993704_994466_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP034784.1\|AZV99074.1\|980027_981590_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
CP034784.1\|AZV99082.1\|988559_989987_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
CP034784.1\|AZV99071.1\|974536_975271_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP034784.1\|AZV99080.1\|986360_987398_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
CP034784.1\|AZV99070.1\|972749_974462_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
CP034784.1\|AZV99079.1\|985494_985788_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP034784.1\|AZV99078.1\|984574_985498_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP034784.1\|AZV99075.1\|981586_982123_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
CP034784.1\|AZV99086.1\|991488_992199_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP034784.1\|AZV99083.1\|989986_990592_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP034784.1\|AZV99077.1\|983200_983947_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
CP034784.1\|AZV99085.1\|991158_991470_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP034784.1\|AZV99081.1\|987649_988558_+\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP034784.1\|AZV99076.1\|982134_983190_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
CP034784.1\|AZV99087.1\|992198_992678_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP034784.1\|AZV99073.1\|975880_976993_-\|IS4-like-element-IS421-family-transposase	unknown	unknown	gnl\|CDD\|376573
CP034784.1\|AZV99072.1\|975535_975688_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
CP034784.1\|AZV99088.1\|992674_993724_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZV99084.1\|990641_990965_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
CP034784.1\|AZV99089.1\|993704_994466_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
CP034784.1\|AZV99074.1\|980027_981590_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
CP034784.1\|AZV99082.1\|988559_989987_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP034784.1\|AZV99071.1\|974536_975271_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	4.32685e-138
CP034784.1\|AZV99080.1\|986360_987398_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP034784.1\|AZV99070.1\|972749_974462_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP034784.1\|AZV99079.1\|985494_985788_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.21674e-65
CP034784.1\|AZV99078.1\|984574_985498_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	8.96044e-158
CP034784.1\|AZV99075.1\|981586_982123_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	1.12087e-29
CP034784.1\|AZV99086.1\|991488_992199_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
CP034784.1\|AZV99083.1\|989986_990592_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	1.20197e-146
CP034784.1\|AZV99077.1\|983200_983947_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.94879e-48
CP034784.1\|AZV99085.1\|991158_991470_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
CP034784.1\|AZV99081.1\|987649_988558_+\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP034784.1\|AZV99076.1\|982134_983190_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.80924e-154
CP034784.1\|AZV99087.1\|992198_992678_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
CP034784.1\|AZV99073.1\|975880_976993_-\|IS4-like-element-IS421-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.16058e-15
CP034784.1\|AZV99072.1\|975535_975688_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	4.96653e-13
CP034784.1\|AZV99088.1\|992674_993724_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0

>CP034784.1|AZV99079.1|985494_985788_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMIVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>CP034784.1|AZV99078.1|984574_985498_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDLVVPKAFEIAARQPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>CP034784.1|AZV99077.1|983200_983947_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDRFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>CP034784.1|AZV99076.1|982134_983190_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKVLAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLEVAVQRITTLRENMNTVYEQKTDYASFDVMNKQGSMKDVLDFICA
>CP034784.1|AZV99075.1|981586_982123_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>CP034784.1|AZV99074.1|980027_981590_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDISAPRADLQGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFMQDFEALTGDKVPVASLLPEIPGAQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWINVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDEQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLDKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLSKWNKEIWLFARQDFDERVFTNPYEPVDLERVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>CP034784.1|AZV99073.1|975880_976993_-|IS4-like-element-IS421-family-transposase
MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLLRLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAVTGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFAQTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGLDCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQAETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPELAKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN
>CP034784.1|AZV99072.1|975535_975688_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>CP034784.1|AZV99071.1|974536_975271_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>CP034784.1|AZV99070.1|972749_974462_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWIKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>CP034784.1|AZV99080.1|986360_987398_-|aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>CP034784.1|AZV99081.1|987649_988558_+|sulfate-adenylyltransferase-subunit-2
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>CP034784.1|AZV99082.1|988559_989987_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEKTFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMAWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>CP034784.1|AZV99083.1|989986_990592_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRYFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>CP034784.1|AZV99084.1|990641_990965_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>CP034784.1|AZV99085.1|991158_991470_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>CP034784.1|AZV99086.1|991488_992199_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>CP034784.1|AZV99087.1|992198_992678_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>CP034784.1|AZV99088.1|992674_993724_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>CP034784.1|AZV99089.1|993704_994466_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: CP034784_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_3

1480645-1480762

TypeV

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034784_3

>merge|CP034784|3|1480645-1480762|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>CP034784|3|3|1480645-1480762|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZV99515.1\|1475021_1476101_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
CP034784.1\|AZV99519.1\|1479163_1479418_-\|2Fe-2S-ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182668
CP034784.1\|AZV99511.1\|1469321_1470512_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
CP034784.1\|AZV99513.1\|1471757_1473386_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
CP034784.1\|AZV99524.1\|1498146_1499796_+\|DUF2300-domain-containing-protein	unknown	unknown	gnl\|CDD\|227732
CP034784.1\|AZV99518.1\|1478459_1479110_+\|lipopolysaccharide-kinase-InaA	unknown	unknown	gnl\|CDD\|182136
CP034784.1\|AZV99525.1\|1499800_1500577_+\|DUF2135-domain-containing-protein	unknown	unknown	gnl\|CDD\|227021
CP034784.1\|AZV99516.1\|1476145_1477024_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP034784.1\|AZV99512.1\|1470508_1471768_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B	unknown	unknown	gnl\|CDD\|225617
CP034784.1\|AZV99523.1\|1488529_1491157_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502
CP034784.1\|AZV99521.1\|1480781_1483067_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
CP034784.1\|AZV99522.1\|1483762_1487521_+\|AIDA-I-family-autotransporter-YfaL	unknown	unknown	gnl\|CDD\|182059
CP034784.1\|AZV99520.1\|1479417_1480548_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	unknown	unknown	gnl\|CDD\|181647
CP034784.1\|AZV99517.1\|1477188_1478379_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
CP034784.1\|AZV99526.1\|1500851_1503701_+\|two-component-system-sensor-histidine-kinase-RcsC	unknown	unknown	gnl\|CDD\|182772
CP034784.1\|AZV99514.1\|1473658_1475017_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
CP034784.1\|AZV99529.1\|1507977_1509075_+\|porin-OmpC	unknown	unknown	gnl\|CDD\|182543
CP034784.1\|AZW02072.1\|1487660_1488383_-\|bifunctional-2-polyprenyl-6-hydroxyphenol-methylase/3-demethylubiquinol-3-O-methyltransferase-UbiG	unknown	unknown	gnl\|CDD\|235350
CP034784.1\|AZV99527.1\|1503899_1504550_-\|transcriptional-regulator-RcsB	unknown	unknown	gnl\|CDD\|182771
CP034784.1\|AZV99528.1\|1504566_1507239_-\|phosphotransferase-RcsD	unknown	unknown	gnl\|CDD\|236726

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZV99515.1\|1475021_1476101_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
CP034784.1\|AZV99519.1\|1479163_1479418_-\|2Fe-2S-ferredoxin-like-protein	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
CP034784.1\|AZV99511.1\|1469321_1470512_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
CP034784.1\|AZV99513.1\|1471757_1473386_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
CP034784.1\|AZV99524.1\|1498146_1499796_+\|DUF2300-domain-containing-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	6.0953e-127
CP034784.1\|AZV99518.1\|1478459_1479110_+\|lipopolysaccharide-kinase-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	1.58207e-157
CP034784.1\|AZV99525.1\|1499800_1500577_+\|DUF2135-domain-containing-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	8.48204e-152
CP034784.1\|AZV99516.1\|1476145_1477024_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.9243e-45
CP034784.1\|AZV99512.1\|1470508_1471768_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
CP034784.1\|AZV99523.1\|1488529_1491157_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
CP034784.1\|AZV99521.1\|1480781_1483067_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
CP034784.1\|AZV99522.1\|1483762_1487521_+\|AIDA-I-family-autotransporter-YfaL	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
CP034784.1\|AZV99520.1\|1479417_1480548_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
CP034784.1\|AZV99517.1\|1477188_1478379_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.45631e-99
CP034784.1\|AZV99526.1\|1500851_1503701_+\|two-component-system-sensor-histidine-kinase-RcsC	gnl\|CDD\|182772	PRK10841, PRK10841, two-component system sensor histidine kinase RcsC.	0
CP034784.1\|AZV99514.1\|1473658_1475017_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
CP034784.1\|AZV99529.1\|1507977_1509075_+\|porin-OmpC	gnl\|CDD\|182543	PRK10554, PRK10554, outer membrane porin protein C; Provisional.	0
CP034784.1\|AZW02072.1\|1487660_1488383_-\|bifunctional-2-polyprenyl-6-hydroxyphenol-methylase/3-demethylubiquinol-3-O-methyltransferase-UbiG	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	2.23684e-170
CP034784.1\|AZV99527.1\|1503899_1504550_-\|transcriptional-regulator-RcsB	gnl\|CDD\|182771	PRK10840, PRK10840, transcriptional regulator RcsB; Provisional.	2.27775e-154
CP034784.1\|AZV99528.1\|1504566_1507239_-\|phosphotransferase-RcsD	gnl\|CDD\|236726	PRK10618, PRK10618, phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional.	0

>CP034784.1|AZV99520.1|1479417_1480548_-|ribonucleoside-diphosphate-reductase-1-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>CP034784.1|AZV99519.1|1479163_1479418_-|2Fe-2S-ferredoxin-like-protein
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>CP034784.1|AZV99518.1|1478459_1479110_+|lipopolysaccharide-kinase-InaA
MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVTPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRHKAINHDFRQLEKYLEPIPKADWEQVKAYYYAR
>CP034784.1|AZV99517.1|1477188_1478379_+|MFS-transporter
MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLHASPDKAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILVLSSLAFLVVTALYPFCHSIESLLFIRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWEAFNMAFWLCTGVAAVGIILSLIMTVPPVISHADGSKPKMGFAAMFDRAALPFAMVTFFMTFSYAGVSAFLALYARELNLMSAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYPCLLFFTVGLVVLGYTQGSVMMVVSGALIGIGYGSVTPVFQMQIISSVEPHKIGVANSLFFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVALVVAKEIH
>CP034784.1|AZV99516.1|1476145_1477024_-|LysR-family-transcriptional-regulator
MTLTQIHTLLAVLDYGGFTEASKRLFMTQSAVSQAIATLEQELGVEILIRERRKALQLTDAGSRIASHLRAITREVNAVKEIAEQEKHNPTRTLRIGCFPSACACILPGIIRYFETYHPQIKIIPYEENSSEIIDSVQNETIDAGFVHFPVTEMYSVPVYQDKFTVVLPDAHPLAKNNAISVEELVGEPLIISKGRYELSIMALFKEKNITPVIKYEFNHPDTAISFIRQGLGIALLPELTLKAVAGELCSVPLEPTFYRQISLLVKEAPVEGSPLFLLQMCMETLVVKGIL
>CP034784.1|AZV99515.1|1475021_1476101_+|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLHKDN
>CP034784.1|AZV99514.1|1473658_1475017_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRNGG
>CP034784.1|AZV99513.1|1471757_1473386_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAQTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>CP034784.1|AZV99512.1|1470508_1471768_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSAPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDDEENWPLLLDALIPVANTCEMILMPACFGLADDKLWHWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>CP034784.1|AZV99511.1|1469321_1470512_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>CP034784.1|AZV99521.1|1480781_1483067_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>CP034784.1|AZV99522.1|1483762_1487521_+|AIDA-I-family-autotransporter-YfaL
MRIIFLRKEYLSLLPSMIASLFSVNSIAEVLDSCQGYDIKASCQASRQSLSGITQDWSIADGQWVIFSGMANNASGGAVFLQQSAEFTISPHNETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGVADLRITNAMFSNNIANDGKGGAIYTINNDVYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDITHPSGFTIINNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLIDENNSAAGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDNHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLTLEGDAADLAALQDEPQSIVLNGGVLGLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGSDGKDGVYVVVDAGDGQVSLANDNQYLGTTQIASGTLVVSDNSQLGDTHYNRQVIFTDNQQESVMEITANVDTRSTTVEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIFPYASSLWIGDGATFETGADQDIQSIDATSSGTIDISDGTVLRLTSQDTSAALDASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGDLTNMSGTVSLQNGVAGDTLTVNGDYTGGGTLFLDSELNGDDSVSDQLVLNGNTSGNTTVVVNPITGTGEPTSTGIKVVDFTADPTQFQNNALFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPTPPPDPDPTPDPDPTPDPDPTPDPAPAPTPAYQPVLNAKVGGYLNNLRAANQAFVMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGNLLSGYWGDDGQWMLGAVGGYSDNQGDSRSNMTGTRADSQNHGYAVGLTSSWFQRGSQKQGAWLDSWLQYAWFSNDVSEQGDGADHYHSSGIIASLEAGYQWLPGHGVVIEPQAQVIYQGVQQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAVHVTPTLDLNYYHDPHPTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVVWQKGDNDFAQTAGFLSMTVKW
>CP034784.1|AZW02072.1|1487660_1488383_-|bifunctional-2-polyprenyl-6-hydroxyphenol-methylase/3-demethylubiquinol-3-O-methyltransferase-UbiG
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGHYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMIGLHYNPITNTFKLGPGVDVNYMLHTQNK
>CP034784.1|AZV99523.1|1488529_1491157_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>CP034784.1|AZV99524.1|1498146_1499796_+|DUF2300-domain-containing-protein
MNWRRIVWLLALVTLPTLAEETPLQLALRGAQHDQLYQLSSSGVTKVSALPDTLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLPTLKPETSVTVKSLLDSLATLPAQNKAQEILLDVVLDEAKIGVASMLGSRVRVKTWSWFADDEQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAVKPGVLNGRYRVTFANGNHITFVSHGETTLLTEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSAMQRVSASPATTGARMMTAWTQDLIYAGDPVHYHGSRATEGTLSWRQATVQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKMPQWRGMLQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>CP034784.1|AZV99525.1|1499800_1500577_+|DUF2135-domain-containing-protein
MRKIFFPLLLVALSPVAHSEGVQEVEIDAPLSGWHPADGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGAGVIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>CP034784.1|AZV99526.1|1500851_1503701_+|two-component-system-sensor-histidine-kinase-RcsC
MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQRESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPVFEPLFADSDCSAMSNTWRVSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGLRDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANRLQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKSDPRWMQERSWFGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLARMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLNMLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRVKMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGSQFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQEPTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARIYLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVIIQTLTVYAERVRKSRES
>CP034784.1|AZV99527.1|1503899_1504550_-|transcriptional-regulator-RcsB
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
>CP034784.1|AZV99528.1|1504566_1507239_-|phosphotransferase-RcsD
MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNAWLKDKSYQIVDITHAIQKRVDTWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYLEKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENIPWSMYYLNGQDNSLVLISTLPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNLRRLAWQNGHYFTLRTTFNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNENEKEGTDSVSIHFNSTKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFSSRSTESVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHLNLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQAQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDEIQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGDRDALQRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLHFPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPEVEEEEERLLDDVCIMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNPSNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLGGDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPGKQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL
>CP034784.1|AZV99529.1|1507977_1509075_+|porin-OmpC
MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYFSDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGLVDGLDFAVQYQGKNGSARGEGMTTNGRNDVFEQNGDGVGGSITYNYEGFGIGAAVSSSKRTDAQNNTADYIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

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Crispr_ID: CP034784_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_4

2090333-2090456

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034784_4

>merge|CP034784|4|2090333-2090456|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>CP034784|4|4|2090333-2090456|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZW00044.1\|2085884_2086553_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
CP034784.1\|AZW00052.1\|2095774_2096986_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
CP034784.1\|AZW00053.1\|2097098_2098031_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
CP034784.1\|AZW00054.1\|2098027_2099053_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
CP034784.1\|AZW00048.1\|2089892_2090198_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
CP034784.1\|AZW00041.1\|2082420_2083047_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
CP034784.1\|AZW00051.1\|2093655_2094297_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
CP034784.1\|AZW00056.1\|2099605_2100775_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
CP034784.1\|AZW00045.1\|2086549_2087335_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
CP034784.1\|AZW00055.1\|2099350_2099440_+\|YnhF-family-membrane-protein	unknown	unknown	unknown
CP034784.1\|AZW00050.1\|2092067_2093441_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
CP034784.1\|AZW00043.1\|2085173_2085821_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
CP034784.1\|AZW00042.1\|2083067_2085170_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
CP034784.1\|AZW00058.1\|2101718_2102534_-\|peptidoglycan-endopeptidase	unknown	unknown	gnl\|CDD\|366353
CP034784.1\|AZW00040.1\|2081756_2081966_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
CP034784.1\|AZW00039.1\|2079787_2081200_-\|pyruvate-kinase-I	unknown	unknown	gnl\|CDD\|181699
CP034784.1\|AZW00047.1\|2088162_2089767_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
CP034784.1\|AZW00057.1\|2101009_2101591_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
CP034784.1\|AZW00049.1\|2090770_2092027_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
CP034784.1\|AZW00046.1\|2087338_2088151_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZW00044.1\|2085884_2086553_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
CP034784.1\|AZW00052.1\|2095774_2096986_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
CP034784.1\|AZW00053.1\|2097098_2098031_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
CP034784.1\|AZW00054.1\|2098027_2099053_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
CP034784.1\|AZW00048.1\|2089892_2090198_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
CP034784.1\|AZW00041.1\|2082420_2083047_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
CP034784.1\|AZW00051.1\|2093655_2094297_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
CP034784.1\|AZW00056.1\|2099605_2100775_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
CP034784.1\|AZW00045.1\|2086549_2087335_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.40835e-163
CP034784.1\|AZW00050.1\|2092067_2093441_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
CP034784.1\|AZW00043.1\|2085173_2085821_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	3.717e-122
CP034784.1\|AZW00042.1\|2083067_2085170_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
CP034784.1\|AZW00058.1\|2101718_2102534_-\|peptidoglycan-endopeptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	7.77757e-47
CP034784.1\|AZW00040.1\|2081756_2081966_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
CP034784.1\|AZW00039.1\|2079787_2081200_-\|pyruvate-kinase-I	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
CP034784.1\|AZW00047.1\|2088162_2089767_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
CP034784.1\|AZW00057.1\|2101009_2101591_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
CP034784.1\|AZW00049.1\|2090770_2092027_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
CP034784.1\|AZW00046.1\|2087338_2088151_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	2.57656e-174

>CP034784.1|AZW00048.1|2089892_2090198_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>CP034784.1|AZW00047.1|2088162_2089767_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEDSHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>CP034784.1|AZW00046.1|2087338_2088151_+|hypothetical-protein
MIITQADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>CP034784.1|AZW00045.1|2086549_2087335_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQTHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>CP034784.1|AZW00044.1|2085884_2086553_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>CP034784.1|AZW00043.1|2085173_2085821_+|YdhW-family-putative-oxidoreductase-system-protein
MGKMNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYLVAEEELSVLLESIKQNGDYADIACLTGSKDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>CP034784.1|AZW00042.1|2083067_2085170_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>CP034784.1|AZW00041.1|2082420_2083047_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>CP034784.1|AZW00040.1|2081756_2081966_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>CP034784.1|AZW00039.1|2079787_2081200_-|pyruvate-kinase-I
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>CP034784.1|AZW00049.1|2090770_2092027_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINLNGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>CP034784.1|AZW00050.1|2092067_2093441_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
>CP034784.1|AZW00051.1|2093655_2094297_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>CP034784.1|AZW00052.1|2095774_2096986_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>CP034784.1|AZW00053.1|2097098_2098031_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>CP034784.1|AZW00054.1|2098027_2099053_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>CP034784.1|AZW00055.1|2099350_2099440_+|YnhF-family-membrane-protein
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>CP034784.1|AZW00056.1|2099605_2100775_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>CP034784.1|AZW00057.1|2101009_2101591_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
>CP034784.1|AZW00058.1|2101718_2102534_-|peptidoglycan-endopeptidase
MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKADKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASASFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR

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Crispr_ID: CP034784_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_6

2880032-2880237

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTACGGCAGTGAAC	CRT
TTTCTAAGCTGCCTGTACGGCAGTGAACG	PILER-CR

3 spacers

The CRISPR arrays of CP034784_6

>merge|CP034784|6|2880032-2880237|CRISPRCasFinder,CRT,PILER-CR
CATTTTATCTGTCTGTACGGCAGTGAACATGGTGGGTGGAGTATGTTACCTGTGAATTTCTAAGCTGCCTGTACGGCAGTGAACGCCAACTTTCACAGCCTTTGCAAGATTGTTCCTTTCTAAGCTGCCTGTACGGCAGTGAACGTTCGCTGCAACCGCTAGCCAAGACGGTAGGTTTTTCTAAGCTGCCTGTACGGCAGTGAACT

>CP034784|6|6|2880032-2880236|CRISPRCasFinder
CATTTTATCTGTCTGTACGGCAGTGAAC	ATGGTGGGTGGAGTATGTTACCTGTGAA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GCCAACTTTCACAGCCTTTGCAAGATTGTTCC
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GTTCGCTGCAACCGCTAGCCAAGACGGTAGGTT
TTTCTAAGCTGCCTGTACGGCAGTGAAC

>CP034784|6|3|2880032-2880236|CRT
CATTTTATCTGTCTGTACGGCAGTGAAC	ATGGTGGGTGGAGTATGTTACCTGTGAA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GCCAACTTTCACAGCCTTTGCAAGATTGTTCC
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GTTCGCTGCAACCGCTAGCCAAGACGGTAGGTT
TTTCTAAGCTGCCTGTACGGCAGTGAAC

>CP034784|6|3|2880088-2880237|PILER-CR
TTTCTAAGCTGCCTGTACGGCAGTGAACG	CCAACTTTCACAGCCTTTGCAAGATTGTTCC
TTTCTAAGCTGCCTGTACGGCAGTGAACG	TTCGCTGCAACCGCTAGCCAAGACGGTAGGTT
TTTCTAAGCTGCCTGTACGGCAGTGAACT

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZW00700.1\|2874909_2876676_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
CP034784.1\|AZW00706.1\|2883396_2883621_+\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
CP034784.1\|AZW00709.1\|2886866_2887859_+\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
CP034784.1\|AZW00711.1\|2889938_2890634_+\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
CP034784.1\|AZW00705.1\|2882753_2883074_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
CP034784.1\|AZW00704.1\|2880446_2882723_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
CP034784.1\|AZW00702.1\|2878439_2879144_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
CP034784.1\|AZW00712.1\|2891128_2892028_+\|lysine-exporter-LysO-family-protein	unknown	unknown	gnl\|CDD\|225287
CP034784.1\|AZW00707.1\|2883693_2885640_-\|macrolide-ABC-transporter-permease/ATP-binding-protein-MacB	unknown	unknown	gnl\|CDD\|182528
CP034784.1\|AZW00708.1\|2885636_2886752_-\|MacA-family-efflux-pump-subunit	unknown	unknown	gnl\|CDD\|183211
CP034784.1\|AZW00713.1\|2892171_2893824_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
CP034784.1\|AZW00703.1\|2879428_2879647_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
CP034784.1\|AZW00701.1\|2876676_2878398_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
CP034784.1\|AZW00696.1\|2867892_2868504_-\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
CP034784.1\|AZW00695.1\|2866538_2867882_-\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
CP034784.1\|AZW00697.1\|2868658_2872648_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
CP034784.1\|AZW00699.1\|2873821_2874787_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
CP034784.1\|AZW00698.1\|2872782_2873277_-\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
CP034784.1\|AZW00710.1\|2887855_2889514_-\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
CP034784.1\|AZW00694.1\|2865155_2866448_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZW00700.1\|2874909_2876676_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
CP034784.1\|AZW00706.1\|2883396_2883621_+\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
CP034784.1\|AZW00709.1\|2886866_2887859_+\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	8.48293e-133
CP034784.1\|AZW00711.1\|2889938_2890634_+\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.04944e-144
CP034784.1\|AZW00705.1\|2882753_2883074_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
CP034784.1\|AZW00704.1\|2880446_2882723_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
CP034784.1\|AZW00702.1\|2878439_2879144_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	3.45002e-139
CP034784.1\|AZW00712.1\|2891128_2892028_+\|lysine-exporter-LysO-family-protein	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	4.37433e-118
CP034784.1\|AZW00707.1\|2883693_2885640_-\|macrolide-ABC-transporter-permease/ATP-binding-protein-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
CP034784.1\|AZW00708.1\|2885636_2886752_-\|MacA-family-efflux-pump-subunit	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
CP034784.1\|AZW00713.1\|2892171_2893824_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
CP034784.1\|AZW00703.1\|2879428_2879647_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
CP034784.1\|AZW00701.1\|2876676_2878398_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
CP034784.1\|AZW00696.1\|2867892_2868504_-\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
CP034784.1\|AZW00695.1\|2866538_2867882_-\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
CP034784.1\|AZW00697.1\|2868658_2872648_-\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
CP034784.1\|AZW00699.1\|2873821_2874787_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
CP034784.1\|AZW00698.1\|2872782_2873277_-\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
CP034784.1\|AZW00710.1\|2887855_2889514_-\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
CP034784.1\|AZW00694.1\|2865155_2866448_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0

>CP034784.1|AZW00703.1|2879428_2879647_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>CP034784.1|AZW00702.1|2878439_2879144_+|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
>CP034784.1|AZW00701.1|2876676_2878398_+|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFIFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTHVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>CP034784.1|AZW00700.1|2874909_2876676_+|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELALTDPLTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLTDWDVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
>CP034784.1|AZW00699.1|2873821_2874787_+|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>CP034784.1|AZW00698.1|2872782_2873277_-|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>CP034784.1|AZW00697.1|2868658_2872648_-|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVPPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAPQQQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>CP034784.1|AZW00696.1|2867892_2868504_-|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>CP034784.1|AZW00695.1|2866538_2867882_-|replication-associated-recombination-protein-A
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>CP034784.1|AZW00694.1|2865155_2866448_-|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
>CP034784.1|AZW00704.1|2880446_2882723_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKAKNELTYGFQSAQKHKAEAAH
>CP034784.1|AZW00705.1|2882753_2883074_-|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>CP034784.1|AZW00706.1|2883396_2883621_+|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>CP034784.1|AZW00707.1|2883693_2885640_-|macrolide-ABC-transporter-permease/ATP-binding-protein-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>CP034784.1|AZW00708.1|2885636_2886752_-|MacA-family-efflux-pump-subunit
MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>CP034784.1|AZW00709.1|2886866_2887859_+|DUF535-domain-containing-protein
MVKSTSCITIDFMNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRECMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
>CP034784.1|AZW00710.1|2887855_2889514_-|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRMAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>CP034784.1|AZW00711.1|2889938_2890634_+|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD
>CP034784.1|AZW00712.1|2891128_2892028_+|lysine-exporter-LysO-family-protein
MFSGLLIILVPLIVGYLIPLRQKAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>CP034784.1|AZW00713.1|2892171_2893824_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

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Crispr_ID: CP034784_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_7

3000153-3000297

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034784_7

>merge|CP034784|7|3000153-3000297|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>CP034784|7|7|3000153-3000297|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZW00818.1\|3009533_3010223_-\|molybdenum-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181841
CP034784.1\|AZW00816.1\|3007653_3008472_+\|pyridoxal-phosphatase	unknown	unknown	gnl\|CDD\|182523
CP034784.1\|AZW00802.1\|2989437_2990346_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
CP034784.1\|AZW00811.1\|3000320_3002582_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
CP034784.1\|AZW00809.1\|2998175_2998652_+\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
CP034784.1\|AZW00819.1\|3010222_3010996_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
CP034784.1\|AZW00808.1\|2996827_2998117_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
CP034784.1\|AZW00803.1\|2990537_2992559_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP034784.1\|AZW00815.1\|3006503_3007499_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
CP034784.1\|AZW00814.1\|3005509_3006463_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
CP034784.1\|AZW00801.1\|2988051_2989041_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
CP034784.1\|AZW00806.1\|2994549_2995704_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
CP034784.1\|AZW00812.1\|3002764_3004198_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
CP034784.1\|AZW00820.1\|3011162_3011312_-\|multidrug-efflux-pump-associated-protein,-AcrZ-family	unknown	unknown	gnl\|CDD\|371231
CP034784.1\|AZW00804.1\|2993137_2993815_-\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
CP034784.1\|AZW00813.1\|3004273_3005326_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
CP034784.1\|AZW00810.1\|2998803_3000087_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
CP034784.1\|AZW00807.1\|2995700_2996741_-\|biotin-synthase	unknown	unknown	gnl\|CDD\|185063
CP034784.1\|AZW00805.1\|2993807_2994563_-\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
CP034784.1\|AZW00817.1\|3008472_3009531_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZW00818.1\|3009533_3010223_-\|molybdenum-ABC-transporter-permease	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
CP034784.1\|AZW00816.1\|3007653_3008472_+\|pyridoxal-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
CP034784.1\|AZW00802.1\|2989437_2990346_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.22556e-139
CP034784.1\|AZW00811.1\|3000320_3002582_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
CP034784.1\|AZW00809.1\|2998175_2998652_+\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.08182e-118
CP034784.1\|AZW00819.1\|3010222_3010996_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
CP034784.1\|AZW00808.1\|2996827_2998117_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
CP034784.1\|AZW00803.1\|2990537_2992559_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP034784.1\|AZW00815.1\|3006503_3007499_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
CP034784.1\|AZW00814.1\|3005509_3006463_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
CP034784.1\|AZW00801.1\|2988051_2989041_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
CP034784.1\|AZW00806.1\|2994549_2995704_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
CP034784.1\|AZW00812.1\|3002764_3004198_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
CP034784.1\|AZW00820.1\|3011162_3011312_-\|multidrug-efflux-pump-associated-protein,-AcrZ-family	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
CP034784.1\|AZW00804.1\|2993137_2993815_-\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	3.39733e-110
CP034784.1\|AZW00813.1\|3004273_3005326_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
CP034784.1\|AZW00810.1\|2998803_3000087_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
CP034784.1\|AZW00807.1\|2995700_2996741_-\|biotin-synthase	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
CP034784.1\|AZW00805.1\|2993807_2994563_-\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	7.9121e-172
CP034784.1\|AZW00817.1\|3008472_3009531_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0

>CP034784.1|AZW00810.1|2998803_3000087_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>CP034784.1|AZW00809.1|2998175_2998652_+|kinase-inhibitor
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>CP034784.1|AZW00808.1|2996827_2998117_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANTSLAILESGDWQQQVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>CP034784.1|AZW00807.1|2995700_2996741_-|biotin-synthase
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>CP034784.1|AZW00806.1|2994549_2995704_-|8-amino-7-oxononanoate-synthase
MSWQDKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWKQSAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFVHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>CP034784.1|AZW00805.1|2993807_2994563_-|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
>CP034784.1|AZW00804.1|2993137_2993815_-|ATP-dependent-dethiobiotin-synthetase-BioD
MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL
>CP034784.1|AZW00803.1|2990537_2992559_-|excinuclease-ABC-subunit-B
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>CP034784.1|AZW00802.1|2989437_2990346_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHNALEKALQALG
>CP034784.1|AZW00801.1|2988051_2989041_-|GTP-3',8-cyclase-MoaA
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
>CP034784.1|AZW00811.1|3000320_3002582_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>CP034784.1|AZW00812.1|3002764_3004198_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>CP034784.1|AZW00813.1|3004273_3005326_-|4-oxalomesaconate-tautomerase
MKKIPCVMMQGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>CP034784.1|AZW00814.1|3005509_3006463_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>CP034784.1|AZW00815.1|3006503_3007499_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>CP034784.1|AZW00816.1|3007653_3008472_+|pyridoxal-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>CP034784.1|AZW00817.1|3008472_3009531_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>CP034784.1|AZW00818.1|3009533_3010223_-|molybdenum-ABC-transporter-permease
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>CP034784.1|AZW00819.1|3010222_3010996_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQFKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASVQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK
>CP034784.1|AZW00820.1|3011162_3011312_-|multidrug-efflux-pump-associated-protein,-AcrZ-family
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: CP034784_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_8

3237115-3237211

Orphan

Consensus_repeat	Method
TTGTAGGCCTGATAAGATGCGTCAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034784_8

>merge|CP034784|8|3237115-3237211|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGCATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGGTTGTAGGCCTGATAAGACGCGTCAAGC

>CP034784|8|8|3237115-3237211|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGC	ATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGG
TTGTAGGCCTGATAAGACGCGTCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZW00995.1\|3235476_3235986_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
CP034784.1\|AZW00992.1\|3232580_3233966_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
CP034784.1\|AZW00994.1\|3234636_3235359_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
CP034784.1\|AZW00993.1\|3234139_3234634_+\|peptidylprolyl-isomerase-B	unknown	unknown	gnl\|CDD\|182734
CP034784.1\|AZW00991.1\|3232023_3232545_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
CP034784.1\|AZW01002.1\|3243284_3244520_+\|allantoate-amidohydrolase	unknown	unknown	gnl\|CDD\|274471
CP034784.1\|AZW00999.1\|3238960_3240220_-\|DUF1116-domain-containing-protein	unknown	unknown	gnl\|CDD\|377673
CP034784.1\|AZW01001.1\|3242213_3243263_+\|ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|184985
CP034784.1\|AZW01000.1\|3240229_3241897_-\|acyl-CoA-synthetase-FdrA	unknown	unknown	gnl\|CDD\|180395
CP034784.1\|AZW01004.1\|3245543_3246689_-\|glycerate-3-kinase	unknown	unknown	gnl\|CDD\|182152
CP034784.1\|AZW00990.1\|3231703_3231916_+\|ribosome-associated-protein-YbcJ	unknown	unknown	gnl\|CDD\|183166
CP034784.1\|AZW01006.1\|3248068_3249430_-\|allantoinase-AllB	unknown	unknown	gnl\|CDD\|169193
CP034784.1\|AZW01003.1\|3244530_3245316_+\|(S)-ureidoglycine-aminohydrolase	unknown	unknown	gnl\|CDD\|225796
CP034784.1\|AZW00988.1\|3228246_3228831_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|237921
CP034784.1\|AZW01005.1\|3246710_3248012_-\|uracil/xanthine-transporter	unknown	unknown	gnl\|CDD\|183124
CP034784.1\|AZW00997.1\|3237244_3238138_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|181831
CP034784.1\|AZW00987.1\|3226308_3226941_+\|fimbriae-biosynthesis-transcriptional-regulator-FimZ	unknown	unknown	gnl\|CDD\|182154
CP034784.1\|AZW00989.1\|3230835_3231702_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|236760
CP034784.1\|AZW00998.1\|3238134_3238950_-\|DUF2877-domain-containing-protein	unknown	unknown	gnl\|CDD\|378658
CP034784.1\|AZW00996.1\|3235982_3237050_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZW00995.1\|3235476_3235986_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	2.09217e-91
CP034784.1\|AZW00992.1\|3232580_3233966_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
CP034784.1\|AZW00994.1\|3234636_3235359_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	1.25513e-165
CP034784.1\|AZW00993.1\|3234139_3234634_+\|peptidylprolyl-isomerase-B	gnl\|CDD\|182734	PRK10791, PRK10791, peptidylprolyl isomerase B.	9.12357e-121
CP034784.1\|AZW00991.1\|3232023_3232545_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.17059e-30
CP034784.1\|AZW01002.1\|3243284_3244520_+\|allantoate-amidohydrolase	gnl\|CDD\|274471	TIGR03176, AllC, allantoate amidohydrolase. This enzyme catalyzes the breakdown of allantoate, first to ureidoglycine by hydrolysis and then decarboxylation of one of the two equivalent ureido groups. Ureidoglycine then spontaneously exchanges ammonia for water resulting in ureidoglycolate. This enzyme is an alternative to allantoicase (3.5.3.4) which releases urea. [Central intermediary metabolism, Nitrogen metabolism].	0
CP034784.1\|AZW00999.1\|3238960_3240220_-\|DUF1116-domain-containing-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.8369e-131
CP034784.1\|AZW01001.1\|3242213_3243263_+\|ureidoglycolate-dehydrogenase	gnl\|CDD\|184985	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional.	0
CP034784.1\|AZW01000.1\|3240229_3241897_-\|acyl-CoA-synthetase-FdrA	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	0
CP034784.1\|AZW01004.1\|3245543_3246689_-\|glycerate-3-kinase	gnl\|CDD\|182152	PRK09932, PRK09932, glycerate 3-kinase.	0
CP034784.1\|AZW00990.1\|3231703_3231916_+\|ribosome-associated-protein-YbcJ	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	1.38756e-42
CP034784.1\|AZW01006.1\|3248068_3249430_-\|allantoinase-AllB	gnl\|CDD\|169193	PRK08044, PRK08044, allantoinase AllB.	0
CP034784.1\|AZW01003.1\|3244530_3245316_+\|(S)-ureidoglycine-aminohydrolase	gnl\|CDD\|225796	COG3257, GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only].	4.36926e-152
CP034784.1\|AZW00988.1\|3228246_3228831_-\|fimbrial-protein	gnl\|CDD\|237921	PRK15199, fimH, type 1 fimbrin D-mannose specific adhesin FimH.	4.13241e-136
CP034784.1\|AZW01005.1\|3246710_3248012_-\|uracil/xanthine-transporter	gnl\|CDD\|183124	PRK11412, PRK11412, uracil/xanthine transporter.	0
CP034784.1\|AZW00997.1\|3237244_3238138_-\|carbamate-kinase	gnl\|CDD\|181831	PRK09411, PRK09411, carbamate kinase; Reviewed.	0
CP034784.1\|AZW00987.1\|3226308_3226941_+\|fimbriae-biosynthesis-transcriptional-regulator-FimZ	gnl\|CDD\|182154	PRK09935, PRK09935, fimbriae biosynthesis transcriptional regulator FimZ.	1.87301e-140
CP034784.1\|AZW00989.1\|3230835_3231702_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
CP034784.1\|AZW00998.1\|3238134_3238950_-\|DUF2877-domain-containing-protein	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	2.19061e-37
CP034784.1\|AZW00996.1\|3235982_3237050_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	5.70382e-179

>CP034784.1|AZW00996.1|3235982_3237050_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAERSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRADETEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNNPSVMINLIGSDANYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEALIPLLPPEYASGVIWAQSKFG
>CP034784.1|AZW00995.1|3235476_3235986_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRNAQTDEVLENPDPRGAA
>CP034784.1|AZW00994.1|3234636_3235359_+|UDP-2,3-diacylglucosamine-diphosphatase
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>CP034784.1|AZW00993.1|3234139_3234634_+|peptidylprolyl-isomerase-B
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTVSE
>CP034784.1|AZW00992.1|3232580_3233966_-|cysteine--tRNA-ligase
MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
>CP034784.1|AZW00991.1|3232023_3232545_+|metal-dependent-hydrolase
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFNFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTAYGHQVIISELMWVWLPGMLLMGMLWWRRR
>CP034784.1|AZW00990.1|3231703_3231916_+|ribosome-associated-protein-YbcJ
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>CP034784.1|AZW00989.1|3230835_3231702_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>CP034784.1|AZW00988.1|3228246_3228831_-|fimbrial-protein
MDSRLIFRLKVIRPFINMVEIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVKVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGPFSALGYLRVDYQ
>CP034784.1|AZW00987.1|3226308_3226941_+|fimbriae-biosynthesis-transcriptional-regulator-FimZ
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPRETLNYIKSNKCSTNSSTITVLSNREVTILRYLVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI
>CP034784.1|AZW00997.1|3237244_3238138_-|carbamate-kinase
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSGGKPAWIGALSRIEETLAGEAGTCISL
>CP034784.1|AZW00998.1|3238134_3238950_-|DUF2877-domain-containing-protein
MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWMLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQCAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRQFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>CP034784.1|AZW00999.1|3238960_3240220_-|DUF1116-domain-containing-protein
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
>CP034784.1|AZW01000.1|3240229_3241897_-|acyl-CoA-synthetase-FdrA
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATSNDICVTIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDASLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKSRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPTLRNQLITDLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIRPLSPATQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>CP034784.1|AZW01001.1|3242213_3243263_+|ureidoglycolate-dehydrogenase
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQKGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEVLTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHVVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
>CP034784.1|AZW01002.1|3243284_3244520_+|allantoate-amidohydrolase
MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLSGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTLEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSIEKAKKMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAILRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKDLVATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLAIMLYQLAWQK
>CP034784.1|AZW01003.1|3244530_3245316_+|(S)-ureidoglycine-aminohydrolase
MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGHAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
>CP034784.1|AZW01004.1|3245543_3246689_-|glycerate-3-kinase
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQALAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>CP034784.1|AZW01005.1|3246710_3248012_-|uracil/xanthine-transporter
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
>CP034784.1|AZW01006.1|3248068_3249430_-|allantoinase-AllB
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

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Crispr_ID: CP034784_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP034784_9

3376177-3376321

Orphan

Consensus_repeat	Method
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP034784_9

>merge|CP034784|9|3376177-3376321|CRISPRCasFinder
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCATCGGAGCACTTATTGCCGGATGCGGCGTGAACGTCTTATCCGGCCTACGGTTCTGGCACCTTTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT

>CP034784|9|9|3376177-3376321|CRISPRCasFinder
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT	CGGAGCACTTATTGCCGGATGCGGCGTGAACGTCTTATCCGGCCTACGGTTCTGGCACC
TTTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT

Protein	Signature genes	Signature genes Name	Protein_function
CP034784.1\|AZW01124.1\|3381168_3381633_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
CP034784.1\|AZW01125.1\|3381752_3382562_+\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
CP034784.1\|AZW01120.1\|3378935_3379220_-\|pyrimidine/purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|182565
CP034784.1\|AZW01111.1\|3365037_3366411_-\|proline-specific-permease-ProY	unknown	unknown	gnl\|CDD\|182566
CP034784.1\|AZW01121.1\|3379291_3379969_-\|AroM-family-protein	unknown	unknown	gnl\|CDD\|182491
CP034784.1\|AZW01122.1\|3380226_3380418_-\|protein-YaiA	unknown	unknown	gnl\|CDD\|182421
CP034784.1\|AZW02138.1\|3374915_3376100_+\|MFS-transporter-AraJ	unknown	unknown	gnl\|CDD\|182234
CP034784.1\|AZW01123.1\|3380467_3380992_-\|shikimate-kinase-AroL	unknown	unknown	gnl\|CDD\|235153
CP034784.1\|AZW01113.1\|3368052_3368232_-\|hypothetical-protein	unknown	unknown	unknown
CP034784.1\|AZW01118.1\|3376344_3377253_-\|fructokinase	unknown	unknown	gnl\|CDD\|236565
CP034784.1\|AZW01112.1\|3366486_3367806_-\|branched-chain-amino-acid-transporter-carrier-protein-BrnQ	unknown	unknown	gnl\|CDD\|185331
CP034784.1\|AZW01119.1\|3377377_3378289_+\|recombination-associated-protein-RdgC	unknown	unknown	gnl\|CDD\|234726
CP034784.1\|AZW01115.1\|3369565_3370255_-\|phosphate-response-regulator-transcription-factor-PhoB	unknown	unknown	gnl\|CDD\|182277
CP034784.1\|AZW01110.1\|3363064_3364882_-\|maltodextrin-glucosidase	unknown	unknown	gnl\|CDD\|236759
CP034784.1\|AZW01109.1\|3362478_3363060_+\|ACP-phosphodiesterase	unknown	unknown	gnl\|CDD\|182207
CP034784.1\|AZW01114.1\|3368212_3369508_-\|phosphate-regulon-sensor-histidine-kinase-PhoR	unknown	unknown	gnl\|CDD\|182895
CP034784.1\|AZW02139.1\|3378366_3378450_-\|hypothetical-protein	unknown	unknown	unknown
CP034784.1\|AZW01117.1\|3371643_3374790_+\|exonuclease-subunit-SbcC	unknown	unknown	gnl\|CDD\|182330
CP034784.1\|AZW01126.1\|3382578_3383694_-\|diguanylate-cyclase-AdrA	unknown	unknown	gnl\|CDD\|182329
CP034784.1\|AZW01116.1\|3370444_3371647_+\|exonuclease-subunit-SbcD	unknown	unknown	gnl\|CDD\|182871

Protein	Function_ID	Function_description	E-value
CP034784.1\|AZW01124.1\|3381168_3381633_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	3.53224e-80
CP034784.1\|AZW01125.1\|3381752_3382562_+\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.87564e-128
CP034784.1\|AZW01120.1\|3378935_3379220_-\|pyrimidine/purine-nucleoside-phosphorylase	gnl\|CDD\|182565	PRK10579, PRK10579, pyrimidine/purine nucleoside phosphorylase.	5.85948e-64
CP034784.1\|AZW01111.1\|3365037_3366411_-\|proline-specific-permease-ProY	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
CP034784.1\|AZW01121.1\|3379291_3379969_-\|AroM-family-protein	gnl\|CDD\|182491	PRK10481, PRK10481, hypothetical protein; Provisional.	2.25423e-119
CP034784.1\|AZW01122.1\|3380226_3380418_-\|protein-YaiA	gnl\|CDD\|182421	PRK10380, PRK10380, hypothetical protein; Provisional.	5.14477e-31
CP034784.1\|AZW02138.1\|3374915_3376100_+\|MFS-transporter-AraJ	gnl\|CDD\|182234	PRK10091, PRK10091, MFS transport protein AraJ; Provisional.	0
CP034784.1\|AZW01123.1\|3380467_3380992_-\|shikimate-kinase-AroL	gnl\|CDD\|235153	PRK03731, aroL, shikimate kinase AroL.	2.43812e-108
CP034784.1\|AZW01118.1\|3376344_3377253_-\|fructokinase	gnl\|CDD\|236565	PRK09557, PRK09557, fructokinase; Reviewed.	0
CP034784.1\|AZW01112.1\|3366486_3367806_-\|branched-chain-amino-acid-transporter-carrier-protein-BrnQ	gnl\|CDD\|185331	PRK15433, PRK15433, branched-chain amino acid transporter carrier protein BrnQ.	0
CP034784.1\|AZW01114.1\|3368212_3369508_-\|phosphate-regulon-sensor-histidine-kinase-PhoR	gnl\|CDD\|182895	PRK11006, phoR, phosphate regulon sensor histidine kinase PhoR.	0
CP034784.1\|AZW01115.1\|3369565_3370255_-\|phosphate-response-regulator-transcription-factor-PhoB	gnl\|CDD\|182277	PRK10161, PRK10161, phosphate response regulator transcription factor PhoB.	5.1688e-159
CP034784.1\|AZW01110.1\|3363064_3364882_-\|maltodextrin-glucosidase	gnl\|CDD\|236759	PRK10785, PRK10785, maltodextrin glucosidase; Provisional.	0
CP034784.1\|AZW01109.1\|3362478_3363060_+\|ACP-phosphodiesterase	gnl\|CDD\|182207	PRK10045, PRK10045, ACP phosphodiesterase.	1.2444e-135
CP034784.1\|AZW01119.1\|3377377_3378289_+\|recombination-associated-protein-RdgC	gnl\|CDD\|234726	PRK00321, rdgC, recombination associated protein; Reviewed.	0
CP034784.1\|AZW01117.1\|3371643_3374790_+\|exonuclease-subunit-SbcC	gnl\|CDD\|182330	PRK10246, PRK10246, exonuclease subunit SbcC; Provisional.	0
CP034784.1\|AZW01126.1\|3382578_3383694_-\|diguanylate-cyclase-AdrA	gnl\|CDD\|182329	PRK10245, adrA, diguanylate cyclase AdrA; Provisional.	0
CP034784.1\|AZW01116.1\|3370444_3371647_+\|exonuclease-subunit-SbcD	gnl\|CDD\|182871	PRK10966, PRK10966, exonuclease subunit SbcD; Provisional.	0

>CP034784.1|AZW02138.1|3374915_3376100_+|MFS-transporter-AraJ
MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGNLREQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADTPVLAKPLG
>CP034784.1|AZW01117.1|3371643_3374790_+|exonuclease-subunit-SbcC
MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVMQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAVK
>CP034784.1|AZW01116.1|3370444_3371647_+|exonuclease-subunit-SbcD
MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLTAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYIALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLHTLAGEHEA
>CP034784.1|AZW01115.1|3369565_3370255_-|phosphate-response-regulator-transcription-factor-PhoB
MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF
>CP034784.1|AZW01114.1|3368212_3369508_-|phosphate-regulon-sensor-histidine-kinase-PhoR
MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRDFSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNEKVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPHGAEFSIEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHAVNHHESRLNIESTVGKGTRFSFVIPKRLIAKNSD
>CP034784.1|AZW01113.1|3368052_3368232_-|hypothetical-protein
MPKTAINPPLSSFIAISQPMLAYFLCSQNMGVRFYNGWWFFVRMISHVFFTEIVFYTGW
>CP034784.1|AZW01112.1|3366486_3367806_-|branched-chain-amino-acid-transporter-carrier-protein-BrnQ
MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTAAFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRTATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALVILSVAAIIWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGVTEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFGGGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLSQLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAFSDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH
>CP034784.1|AZW01111.1|3365037_3366411_-|proline-specific-permease-ProY
MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHDRQLAENQ
>CP034784.1|AZW01110.1|3363064_3364882_-|maltodextrin-glucosidase
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFIFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEVVLPASPFLNAVQWQCKEGHGQLTDGILALPAISATVWMN
>CP034784.1|AZW01109.1|3362478_3363060_+|ACP-phosphodiesterase
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPNSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASRKAL
>CP034784.1|AZW01118.1|3376344_3377253_-|fructokinase
MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIATLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRLANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPLPWMDEDELRYREEVPCYCGKQGCIETFISGTGFAMDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGECETPVRKAKHGDSSGVRGAAWLWPQE
>CP034784.1|AZW01119.1|3377377_3378289_+|recombination-associated-protein-RdgC
MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELVALIQNLIEGLGGEAQR
>CP034784.1|AZW02139.1|3378366_3378450_-|hypothetical-protein
MTQRPWSKLQRKTHNIAALKIIARRSE
>CP034784.1|AZW01120.1|3378935_3379220_-|pyrimidine/purine-nucleoside-phosphorylase
MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
>CP034784.1|AZW01121.1|3379291_3379969_-|AroM-family-protein
MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREEVMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANISSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSLGNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIARLAAELLV
>CP034784.1|AZW01122.1|3380226_3380418_-|protein-YaiA
MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEHPTAQEAMDAKKRYEDPDKE
>CP034784.1|AZW01123.1|3380467_3380992_-|shikimate-kinase-AroL
MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
>CP034784.1|AZW01124.1|3381168_3381633_-|YaiI/YqxD-family-protein
MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAAINPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRGQM
>CP034784.1|AZW01125.1|3381752_3382562_+|pyrroline-5-carboxylate-reductase
MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS
>CP034784.1|AZW01126.1|3382578_3383694_-|diguanylate-cyclase-AdrA
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP038506	Escherichia coli strain 28Eco12 plasmid p28Eco12, complete sequence	11835-11866	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP019283	Escherichia coli strain 13P484A plasmid p13P484A-3, complete sequence	42147-42178	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	CP042641	Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-3, complete sequence	36520-36551	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP034821	Salmonella sp. SSDFZ54 plasmid pTB502, complete sequence	1557-1588	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP027443	Escherichia coli strain 2013C-3252 plasmid unnamed1, complete sequence	9506-9537	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP027575	Escherichia coli strain 2013C-4081 plasmid unnamed2	94756-94787	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP027223	Escherichia coli strain 2015C-3101 plasmid unnamed2	65534-65565	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP030188	Salmonella enterica strain SA20094620 plasmid pSA20094620.3, complete sequence	61916-61947	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP027590	Escherichia coli strain 2014C-3011 plasmid unnamed2	64165-64196	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP039862	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014880 plasmid p16-6773.2, complete sequence	20286-20317	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP033632	Escherichia coli isolate ECCNB12-2 plasmid pTB-nb1, complete sequence	119284-119315	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_AP018798	Escherichia coli strain E2855 plasmid pE2855-2, complete sequence	85099-85130	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	CP012494	Escherichia coli strain CFSAN004177 plasmid pCFSAN004177G_03, complete sequence	46688-46719	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	CP027320	Escherichia coli strain 2014C-3084 plasmid unnamed1	42116-42147	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NC_013370	Escherichia coli O111:H- str. 11128 plasmid pO111_2, complete sequence	87237-87268	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP026475	Escherichia coli strain KBN10P04869 plasmid pKBN10P04869B, complete sequence	81853-81884	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	MN510445	Escherichia coli strain JIE250 plasmid pJIE250_3, complete sequence	70500-70531	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	MN510447	Escherichia coli strain TZ20_1P plasmid pTZ20_1P, complete sequence	47861-47892	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP012491	Escherichia coli strain CFSAN004176 plasmid pCFSAN004176P_03, complete sequence	62997-63028	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	MH422554	Escherichia phage P1, complete genome	87194-87225	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NC_050152	Enterobacteria phage P7, complete genome	93995-94026	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	MH445380	Escherichia virus P1 isolate transconjugant 2(L-II), complete genome	58645-58676	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NC_031129	Salmonella phage SJ46, complete genome	77363-77394	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	MH445381	Escherichia virus P1, complete genome	56870-56901	0	1.0
CP034784_5	5.1\|2740942\|40\|CP034784\|CRISPRCasFinder	2740942-2740981	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	17440-17471	2	0.938
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP017632	Escherichia coli strain SLK172 plasmid pSLK172-1, complete sequence	122310-122341	2	0.938
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP030285	Escherichia coli strain E308 plasmid pLKSZ04, complete sequence	6029-6060	2	0.938
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	NZ_CP036204	Escherichia coli strain L725 plasmid punnamed2, complete sequence	15121-15152	2	0.938
CP034784_2	2.6\|986219\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986219-986250	32	MN510446	Escherichia coli strain SvETEC plasmid pSvP1_F, complete sequence	131402-131433	2	0.938
CP034784_2	2.7\|986280\|32\|CP034784\|CRT	986280-986311	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	2	0.938
CP034784_4	4.1\|2090376\|38\|CP034784\|CRISPRCasFinder	2090376-2090413	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
CP034784_1	1.4\|958476\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	958476-958507	32	KU686197	Synechococcus phage S-CAM3 isolate 0808SB25, complete genome	118383-118414	5	0.844
CP034784_1	1.4\|958476\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	958476-958507	32	KU686199	Synechococcus phage S-CAM3 isolate 1010CC42, complete genome	118389-118420	5	0.844
CP034784_1	1.4\|958476\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	958476-958507	32	KU686198	Synechococcus phage S-CAM3 isolate 0910TB04, complete genome	118373-118404	5	0.844
CP034784_2	2.7\|986280\|32\|CP034784\|CRT	986280-986311	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
CP034784_1	1.6\|958598\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	958598-958629	32	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	965187-965218	8	0.75
CP034784_1	1.9\|958781\|32\|CP034784\|CRISPRCasFinder,CRT	958781-958812	32	MK814759	Gordonia phage Reyja, complete genome	4467-4498	8	0.75
CP034784_2	2.1\|985914\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	985914-985945	32	MF773750	Mycobacterium phage OKCentral2016, complete genome	32038-32069	8	0.75
CP034784_2	2.1\|985914\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	985914-985945	32	JX307704	Mycobacterium virus Goose, complete genome	32135-32166	8	0.75
CP034784_2	2.3\|986036\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986036-986067	32	NZ_CP042402	Weissella hellenica strain CBA3632 plasmid unnamed3, complete sequence	12282-12313	8	0.75
CP034784_2	2.4\|986097\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986097-986128	32	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	458381-458412	8	0.75
CP034784_2	2.4\|986097\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986097-986128	32	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	130817-130848	8	0.75
CP034784_2	2.7\|986280\|32\|CP034784\|CRT	986280-986311	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	8	0.75
CP034784_2	2.7\|986280\|32\|CP034784\|CRT	986280-986311	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
CP034784_2	2.3\|986036\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986036-986067	32	CP003185	Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome	44776-44807	9	0.719
CP034784_2	2.3\|986036\|32\|CP034784\|PILER-CR,CRISPRCasFinder,CRT	986036-986067	32	NC_019956	Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence	105005-105036	9	0.719
CP034784_6	6.3\|2880176\|33\|CP034784\|CRISPRCasFinder,CRT	2880176-2880208	33	MN855903	Myoviridae sp. isolate 490, partial genome	4171-4203	9	0.727
CP034784_6	6.5\|2880177\|32\|CP034784\|PILER-CR	2880177-2880208	32	MN855903	Myoviridae sp. isolate 490, partial genome	4171-4202	9	0.719

1. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038506 (Escherichia coli strain 28Eco12 plasmid p28Eco12, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

2. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019283 (Escherichia coli strain 13P484A plasmid p13P484A-3, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

3. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to CP042641 (Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-3, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

4. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034821 (Salmonella sp. SSDFZ54 plasmid pTB502, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

5. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027443 (Escherichia coli strain 2013C-3252 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

6. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027575 (Escherichia coli strain 2013C-4081 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

7. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027223 (Escherichia coli strain 2015C-3101 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

8. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030188 (Salmonella enterica strain SA20094620 plasmid pSA20094620.3, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

9. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027590 (Escherichia coli strain 2014C-3011 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

10. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039862 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014880 plasmid p16-6773.2, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

11. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033632 (Escherichia coli isolate ECCNB12-2 plasmid pTB-nb1, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

12. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018798 (Escherichia coli strain E2855 plasmid pE2855-2, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

13. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to CP012494 (Escherichia coli strain CFSAN004177 plasmid pCFSAN004177G_03, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

14. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to CP027320 (Escherichia coli strain 2014C-3084 plasmid unnamed1) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

15. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NC_013370 (Escherichia coli O111:H- str. 11128 plasmid pO111_2, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

16. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026475 (Escherichia coli strain KBN10P04869 plasmid pKBN10P04869B, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

17. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MN510445 (Escherichia coli strain JIE250 plasmid pJIE250_3, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

18. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MN510447 (Escherichia coli strain TZ20_1P plasmid pTZ20_1P, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

19. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012491 (Escherichia coli strain CFSAN004176 plasmid pCFSAN004176P_03, complete sequence) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

20. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MH422554 (Escherichia phage P1, complete genome) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

21. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NC_050152 (Enterobacteria phage P7, complete genome) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

22. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MH445380 (Escherichia virus P1 isolate transconjugant 2(L-II), complete genome) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

23. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NC_031129 (Salmonella phage SJ46, complete genome) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

24. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MH445381 (Escherichia virus P1, complete genome) position: , mismatch: 0, identity: 1.0

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctgaaccgacattcatgt	Protospacer
********************************

25. spacer 5.1|2740942|40|CP034784|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

26. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 2, identity: 0.938

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtgaaaacacgttctgaaccgacattcatgt	Protospacer
***.******** *******************

27. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017632 (Escherichia coli strain SLK172 plasmid pSLK172-1, complete sequence) position: , mismatch: 2, identity: 0.938

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtgaaaacacgttctgaaccgacattcatgt	Protospacer
***.******** *******************

28. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030285 (Escherichia coli strain E308 plasmid pLKSZ04, complete sequence) position: , mismatch: 2, identity: 0.938

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctaaaccgtcattcatgt	Protospacer
****************.***** *********

29. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036204 (Escherichia coli strain L725 plasmid punnamed2, complete sequence) position: , mismatch: 2, identity: 0.938

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacggtctaaaccgtcattcatgt	Protospacer
****************.***** *********

30. spacer 2.6|986219|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MN510446 (Escherichia coli strain SvETEC plasmid pSvP1_F, complete sequence) position: , mismatch: 2, identity: 0.938

ggtaaaaacacggtctgaaccgacattcatgt	CRISPR spacer
ggtaaaaacacgttatgaaccgacattcatgt	Protospacer
************ * *****************

31. spacer 2.7|986280|32|CP034784|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 2, identity: 0.938

ggcgcactggatgcgatgatggatatcacttg	CRISPR spacer
gacgcactggatgcgatgatggacatcacttg	Protospacer
*.*********************.********

32. spacer 4.1|2090376|38|CP034784|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

33. spacer 1.4|958476|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to KU686197 (Synechococcus phage S-CAM3 isolate 0808SB25, complete genome) position: , mismatch: 5, identity: 0.844

ttttgtgattcagtaatcgtttgagtatgtac	CRISPR spacer
atttgtgatacagtaaacgtttgagtatctgc	Protospacer
 ******** ****** *********** *.*

34. spacer 1.4|958476|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to KU686199 (Synechococcus phage S-CAM3 isolate 1010CC42, complete genome) position: , mismatch: 5, identity: 0.844

ttttgtgattcagtaatcgtttgagtatgtac	CRISPR spacer
atttgtgatacagtaaacgtttgagtatctgc	Protospacer
 ******** ****** *********** *.*

35. spacer 1.4|958476|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to KU686198 (Synechococcus phage S-CAM3 isolate 0910TB04, complete genome) position: , mismatch: 5, identity: 0.844

ttttgtgattcagtaatcgtttgagtatgtac	CRISPR spacer
atttgtgatacagtaaacgtttgagtatctgc	Protospacer
 ******** ****** *********** *.*

36. spacer 2.7|986280|32|CP034784|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

ggcgcactggatgcgatgatggat-atcacttg	CRISPR spacer
ggcgcactggctgcgatgaaggacgatcaacc-	Protospacer
********** ******** ***. **** ..

37. spacer 1.6|958598|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cgctgacgcggtaaaaagcggggcgtgattcg	CRISPR spacer
gactgacgcggtaaaaggcggagcgggcattg	Protospacer
 .**************.****.*** *  *.*

38. spacer 1.9|958781|32|CP034784|CRISPRCasFinder,CRT matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.75

gagcctgacgagactactgaggccgttctgtc-	CRISPR spacer
aagcctgacgaggctactggggcca-gcggtgg	Protospacer
.***********.******.****.  * **

39. spacer 2.1|985914|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to MF773750 (Mycobacterium phage OKCentral2016, complete genome) position: , mismatch: 8, identity: 0.75

gagcgtagagattctcgaaaccgatccggacg	CRISPR spacer
cctcgtagagatcctcgaagccgatctcggcg	Protospacer
   *********.******.******. *.**

40. spacer 2.1|985914|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to JX307704 (Mycobacterium virus Goose, complete genome) position: , mismatch: 8, identity: 0.75

gagcgtagagattctcgaaaccgatccggacg	CRISPR spacer
cctcgtagagatcctcgaagccgatctcggcg	Protospacer
   *********.******.******. *.**

41. spacer 2.3|986036|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042402 (Weissella hellenica strain CBA3632 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

gtaataaaaaatattctatttctgctgaatca	CRISPR spacer
gtaataaaaaatctactatttctgattttaga	Protospacer
************ * ********* *     *

42. spacer 2.4|986097|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cttgcgagcaaaagatccaggccgagaaagac	CRISPR spacer
aagccgagcaaaagatccaggcggtgaagggc	Protospacer
    ****************** * ***.*.*

43. spacer 2.4|986097|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

cttgcgagcaaaagatccaggccgagaaagac	CRISPR spacer
aagccgagcaaaagatccaggcggtgaagggc	Protospacer
    ****************** * ***.*.*

44. spacer 2.7|986280|32|CP034784|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.75

ggcgcactggatgcgatgatggatatcacttg	CRISPR spacer
ggcgcactggaaccgatgatggatgcgatgag	Protospacer
***********  ***********.. *.  *

45. spacer 2.7|986280|32|CP034784|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

ggcgcactggatgcgatgatggata---tcacttg	CRISPR spacer
ggcgcactggaagcggtgatggaggggcgcac---	Protospacer
*********** ***.******* .    ***

46. spacer 2.3|986036|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to CP003185 (Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome) position: , mismatch: 9, identity: 0.719

gtaataaaaaatattctatttctgctgaatca	CRISPR spacer
ataataaataatattctgtttctgtgtgttta	Protospacer
.******* ********.******.  . *.*

47. spacer 2.3|986036|32|CP034784|PILER-CR,CRISPRCasFinder,CRT matches to NC_019956 (Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence) position: , mismatch: 9, identity: 0.719

gtaataaaaaatattctatttctgctgaatca	CRISPR spacer
ataataaataatattctgtttctgtgtgttta	Protospacer
.******* ********.******.  . *.*

48. spacer 6.3|2880176|33|CP034784|CRISPRCasFinder,CRT matches to MN855903 (Myoviridae sp. isolate 490, partial genome) position: , mismatch: 9, identity: 0.727

gttcgctgcaaccgctagccaagacggtaggtt	CRISPR spacer
gttcgctgcaaccgttcgccaagaccacaaagg	Protospacer
**************.* ******** ..*..

49. spacer 6.5|2880177|32|CP034784|PILER-CR matches to MN855903 (Myoviridae sp. isolate 490, partial genome) position: , mismatch: 9, identity: 0.719

ttcgctgcaaccgctagccaagacggtaggtt	CRISPR spacer
ttcgctgcaaccgttcgccaagaccacaaagg	Protospacer
*************.* ******** ..*..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

993704 : 1006886

Escherichia_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZV99089.1\|993704_994466_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.4e-59	48.0
AZV99090.1\|994459_995086_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.7e-36	49.7
AZV99091.1\|995225_996365_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-07	35.6
AZV99092.1\|996427_997420_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.1e-32	37.6
AZV99093.1\|997513_998878_-	GntP family transporter	NA	NA	NA	NA
AZV99094.1\|998966_999743_-	HPr family phosphocarrier protein	NA	NA	NA	NA
AZV99095.1\|999747_1000386_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
AZV99096.1\|1000382_1001645_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	8.3e-135	61.0
AZV99097.1\|1001641_1002550_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
AZV99098.1\|1002745_1003513_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.5e-70	56.7
AZV99099.1\|1003563_1004214_-	protein-serine/threonine phosphatase	K7P7V3	Enterobacteria_phage	2.7e-49	45.8
AZV99100.1\|1004324_1006886_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	3.0e-30	20.6

DBSCAN-SWA_2

1602351 : 1611792

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZV99607.1\|1602351_1603278_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.0e-08	26.8
AZV99608.1\|1603282_1604014_+	ABC transporter permease	NA	NA	NA	NA
AZV99609.1\|1603994_1604102_-	protein YohO	NA	NA	NA	NA
AZV99610.1\|1604112_1604892_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	9.8e-86	86.0
AZV99611.1\|1605113_1606799_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
AZV99612.1\|1606795_1607515_+	two-component system response regulator YehT	NA	NA	NA	NA
AZV99613.1\|1607561_1608032_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
AZV99614.1\|1608072_1608534_-	DUF1307 domain-containing protein	Q9EYF5	Enterobacteria_phage	1.6e-75	98.7
AZV99615.1\|1608658_1610659_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.6
AZV99616.1\|1610655_1611792_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.9e-162	97.7

DBSCAN-SWA_3

2387207 : 2401467

Escherichia_phage(38.46%)

lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZW00276.1\|2387207_2388341_+	porin OmpN	Q1MVN1	Enterobacteria_phage	8.3e-118	58.8
AZW00277.1\|2388481_2388916_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
AZW00278.1\|2389691_2389805_+	hypothetical protein	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
AZW00279.1\|2389873_2390107_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
AZW00280.1\|2391537_2392470_-	hypothetical protein	A0A1B1INP7	uncultured_Mediterranean_phage	1.4e-83	54.9
AZW00281.1\|2392462_2393254_-	transcriptional regulator	R4TG31	Halovirus	2.8e-48	40.2
AZW02108.1\|2394985_2395045_-	hypothetical protein	NA	NA	NA	NA
AZW00282.1\|2395445_2395943_-	lysozyme	M1FJA0	Enterobacteria_phage	3.2e-90	97.0
AZW00283.1\|2395942_2396158_-\|lysis	lysis protein S	A5LH82	Enterobacteria_phage	1.3e-32	94.4
AZW02109.1\|2396409_2396784_-	tolA family protein	NA	NA	NA	NA
AZW00284.1\|2396955_2397384_-	cell envelope integrity protein TolA	NA	NA	NA	NA
AZW00285.1\|2398428_2398971_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	2.9e-76	75.7
AZW00286.1\|2398967_2399258_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.7e-46	87.5
AZW00287.1\|2399257_2399857_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.1e-105	92.0
AZW00288.1\|2399759_2399993_-	hypothetical protein	NA	NA	NA	NA
AZW00289.1\|2401102_2401315_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.0e-21	75.7
AZW00290.1\|2401359_2401467_+	hypothetical protein	Q7Y2Q9	Escherichia_phage	1.1e-08	96.6

DBSCAN-SWA_4

2406231 : 2425307

Escherichia_phage(55.56%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZW00295.1\|2406231_2408229_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	3.3e-21	26.2
AZW00296.1\|2408569_2408992_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	4.8e-63	88.5
AZW00297.1\|2409032_2410103_-	phage replisome organizer	A0A088CD36	Shigella_phage	4.7e-62	64.6
AZW00298.1\|2410174_2410600_-	Rha family transcriptional regulator	NA	NA	NA	NA
AZW00299.1\|2410583_2410865_-	Cro/Cl family transcriptional regulator	K7PHA1	Enterobacteria_phage	8.5e-24	72.6
AZW00300.1\|2410965_2411385_+	hypothetical protein	K7PK07	Enterobacteria_phage	8.8e-25	65.1
AZW00301.1\|2411639_2411774_+	hypothetical protein	NA	NA	NA	NA
AZW00302.1\|2411784_2411940_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	6.1e-08	55.3
AZW02110.1\|2411936_2412242_-	superinfection exclusion B family protein	NA	NA	NA	NA
AZW00303.1\|2413642_2413864_+	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
AZW00304.1\|2413863_2414034_+	hypothetical protein	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
AZW00305.1\|2414108_2414384_+	protein RacC	A0A0U2QW85	Escherichia_phage	1.4e-42	96.7
AZW00306.1\|2414485_2417086_+	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	3.9e-248	63.5
AZW00307.1\|2417078_2417888_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	8.8e-106	71.5
AZW00308.1\|2417944_2418139_+	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	5.8e-32	96.9
AZW00309.1\|2418131_2418341_+	double-strand break reduction protein RcbA	A0A0U2QL97	Escherichia_phage	6.1e-27	98.4
AZW00310.1\|2418419_2418635_+	hypothetical protein	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
AZW00311.1\|2418636_2419872_+	DUF3596 domain-containing protein	A0A0U2JGI6	Escherichia_phage	5.5e-240	98.8
AZW00312.1\|2419923_2420859_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
AZW00313.1\|2420987_2422361_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.5e-52	32.9
AZW00314.1\|2424074_2425307_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	3.1e-17	39.5

DBSCAN-SWA_5

3442798 : 3515853

Shigella_phage(52.73%)

capsid,head,terminase,plate,integrase,portal,tail,holin,protease

attL 3456865:3456881|attR 3513299:3513315

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZW01174.1\|3442798_3444832_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	3.4e-21	27.4
AZW02143.1\|3444960_3445548_+	transcriptional regulator BetI	NA	NA	NA	NA
AZW01175.1\|3445561_3447034_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
AZW01176.1\|3447047_3448718_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	4.7e-61	31.2
AZW01177.1\|3448930_3449599_+	hypothetical protein	NA	NA	NA	NA
AZW01178.1\|3449841_3450537_-	lactate utilization protein C	NA	NA	NA	NA
AZW01179.1\|3450529_3451957_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
AZW01180.1\|3453282_3457539_-	intimin-like adhesin FdeC	NA	NA	NA	NA
3456865:3456881	attL	NA	NA	NA	NA
AZW01181.1\|3458653_3458755_+	hypothetical protein	NA	NA	NA	NA
AZW01182.1\|3459118_3459382_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
AZW01183.1\|3459381_3459522_+	50S ribosomal protein L36	NA	NA	NA	NA
AZW02144.1\|3459556_3459784_-	hypothetical protein	NA	NA	NA	NA
AZW02145.1\|3460606_3461149_+	LuxR family transcriptional regulator	NA	NA	NA	NA
AZW01184.1\|3461223_3461811_+	fimbrial protein	NA	NA	NA	NA
AZW01185.1\|3461868_3462537_+	fimbrial chaperone EcpB	NA	NA	NA	NA
AZW01186.1\|3465076_3466720_+	fimbria adhesin EcpD	NA	NA	NA	NA
AZW01187.1\|3466688_3467399_+	hypothetical protein	NA	NA	NA	NA
AZW01188.1\|3467711_3468041_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
AZW01189.1\|3468052_3468283_-	hypothetical protein	NA	NA	NA	NA
AZW01190.1\|3468287_3468902_-	DUF1440 domain-containing protein	NA	NA	NA	NA
AZW01191.1\|3469318_3470008_+	aldehyde dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
AZW01192.1\|3470004_3470961_+	xanthine dehydrogenase family protein subunit M	NA	NA	NA	NA
AZW01193.1\|3470957_3473156_+	xanthine dehydrogenase family protein molybdopterin-binding subunit	A0A0P0I429	Acinetobacter_phage	4.3e-38	25.8
AZW01194.1\|3473165_3474122_+	XdhC family protein	NA	NA	NA	NA
AZW01195.1\|3474100_3474511_+	hypothetical protein	NA	NA	NA	NA
AZW01196.1\|3475189_3475357_-	protein FlxA	NA	NA	NA	NA
AZW01197.1\|3477661_3478189_+\|tail	phage tail protein	Q9MCR6	Enterobacteria_phage	1.2e-82	89.6
AZW01198.1\|3478188_3478803_+\|tail	tail fiber assembly protein	Q9MCR5	Enterobacteria_phage	1.1e-92	85.6
AZW01199.1\|3478768_3478972_-	hypothetical protein	NA	NA	NA	NA
AZW01200.1\|3478946_3479870_-	hypothetical protein	U5P0I1	Shigella_phage	7.8e-50	96.1
AZW01201.1\|3479873_3480458_-	DUF2313 domain-containing protein	O22003	Shigella_phage	4.6e-112	99.0
AZW01202.1\|3480448_3481507_-\|plate	baseplate J/gp47 family protein	U5P424	Shigella_phage	5.6e-201	99.1
AZW01203.1\|3481493_3481919_-\|tail	phage tail protein	U5P0R9	Shigella_phage	2.3e-81	100.0
AZW01204.1\|3481918_3482467_-\|plate	phage baseplate assembly protein V	Q8SBG6	Shigella_phage	1.1e-96	99.5
AZW01205.1\|3482466_3483546_-\|plate	baseplate protein	U5P0H6	Shigella_phage	3.4e-206	99.7
AZW01206.1\|3483542_3484871_-	DNA circularization protein	Q8SBG8	Shigella_phage	1.0e-244	98.0
AZW01207.1\|3484932_3485463_-	hypothetical protein	NA	NA	NA	NA
AZW01208.1\|3485554_3487387_-\|tail	phage tail tape measure protein	S5FM63	Shigella_phage	1.1e-302	98.4
AZW01209.1\|3487373_3487562_-	hypothetical protein	NA	NA	NA	NA
AZW01210.1\|3487528_3487798_-\|tail	phage tail assembly protein	M1FPE4	Enterobacteria_phage	3.5e-43	100.0
AZW01211.1\|3487797_3488154_-\|tail	phage tail protein	U5P076	Shigella_phage	5.3e-63	100.0
AZW01212.1\|3488153_3489650_-\|tail	phage tail protein	S5FKL0	Shigella_phage	1.8e-274	98.2
AZW01213.1\|3489633_3489804_-	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	9.3e-26	100.0
AZW01214.1\|3489812_3490373_-	hypothetical protein	M1FQV7	Enterobacteria_phage	6.8e-105	98.9
AZW01215.1\|3490369_3490876_-	hypothetical protein	M1FPE2	Enterobacteria_phage	6.6e-83	92.3
AZW01216.1\|3490850_3491261_-\|head,tail	head-tail adaptor protein	M1FJ87	Enterobacteria_phage	7.0e-67	91.2
AZW01217.1\|3491257_3491581_-\|head,tail	phage gp6-like head-tail connector protein	U5P072	Shigella_phage	1.1e-56	99.1
AZW01218.1\|3491583_3491784_-	hypothetical protein	S5FNU1	Shigella_phage	1.7e-26	98.5
AZW01219.1\|3491833_3493039_-\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	1.6e-223	99.3
AZW01220.1\|3493053_3493704_-\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	2.5e-119	100.0
AZW01221.1\|3493681_3494923_-\|portal	phage portal protein	U5P411	Shigella_phage	2.0e-242	99.8
AZW01222.1\|3494922_3495105_-	hypothetical protein	S5FXQ9	Shigella_phage	1.7e-25	100.0
AZW02146.1\|3495116_3496613_-\|terminase	terminase large subunit	A0A1C9IIA1	Salmonella_phage	9.7e-300	99.6
AZW01223.1\|3496846_3497341_-\|terminase	phage terminase small subunit P27 family	U5P067	Shigella_phage	4.3e-87	98.8
AZW01224.1\|3497467_3497818_-	HNH endonuclease	M1FQV2	Enterobacteria_phage	3.5e-51	80.2
AZW01225.1\|3497881_3498079_-	hypothetical protein	K7PHC3	Enterobacterial_phage	6.8e-28	95.4
AZW01226.1\|3498143_3498419_-	hypothetical protein	NA	NA	NA	NA
AZW01227.1\|3498485_3499022_-	DUF2514 domain-containing protein	A0A0A0P0G7	Enterobacteria_phage	2.5e-08	48.8
AZW01228.1\|3499018_3499636_-	glycoside hydrolase family 19 protein	Q8HA86	Salmonella_phage	5.2e-90	77.5
AZW01229.1\|3499635_3499917_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	9.7e-20	45.2
AZW01230.1\|3499903_3500290_-	hypothetical protein	A0A192Y8P2	Salmonella_phage	2.7e-60	99.2
AZW02147.1\|3500369_3500627_-	hypothetical protein	A0A1C9IHX4	Salmonella_phage	1.6e-37	94.1
AZW01231.1\|3500777_3501530_-	antitermination protein	Q8SBE4	Shigella_phage	2.4e-137	99.2
AZW01232.1\|3502540_3503350_-	KilA-N domain-containing protein	Q8SBE6	Shigella_phage	6.9e-151	98.1
AZW01233.1\|3503369_3503759_-	RusA family crossover junction endodeoxyribonuclease	A0A291AX14	Escherichia_phage	2.1e-68	99.2
AZW01234.1\|3503755_3504082_-	LexA family transcriptional regulator	A0A0N7KZF7	Stx2-converting_phage	2.7e-53	99.1
AZW01235.1\|3504078_3504732_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	5.6e-127	99.1
AZW01236.1\|3504731_3505226_-	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	6.2e-86	98.1
AZW01237.1\|3505222_3506164_-	helix-turn-helix domain-containing protein	S5FM81	Shigella_phage	1.5e-144	100.0
AZW01238.1\|3506153_3506333_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
AZW01239.1\|3507051_3507312_-	XRE family transcriptional regulator	S5FKP1	Shigella_phage	7.1e-41	100.0
AZW01240.1\|3507409_3508102_+	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	1.0e-126	100.0
AZW01241.1\|3508379_3508676_+	hypothetical protein	Q8SBF7	Shigella_phage	1.2e-52	100.0
AZW01242.1\|3508593_3508839_-	hypothetical protein	NA	NA	NA	NA
AZW01243.1\|3509075_3509297_+	hypothetical protein	S5FNS4	Shigella_phage	2.4e-37	95.9
AZW01244.1\|3509352_3509889_+	HD family hydrolase	S5MW55	Escherichia_phage	1.4e-99	98.3
AZW01245.1\|3509879_3510242_+	hypothetical protein	U5P092	Shigella_phage	1.0e-66	98.3
AZW01246.1\|3510241_3510547_+	hypothetical protein	U5P0J0	Shigella_phage	3.4e-50	99.0
AZW01247.1\|3510462_3510897_+	DNA-binding protein	U5P4J3	Shigella_phage	6.4e-79	100.0
AZW01248.1\|3510773_3511937_+\|integrase	integrase	U5P434	Shigella_phage	9.1e-229	99.7
AZW01249.1\|3512141_3513395_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	9.8e-96	47.2
3513299:3513315	attR	NA	NA	NA	NA
AZW01250.1\|3513406_3514510_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
AZW01251.1\|3514797_3515853_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	5.0e-117	60.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP034785

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

27367 : 90836

Escherichia_phage(36.36%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZW02218.1\|27367_28480_-\|transposase	IS4-like element IS421 family transposase	NA	NA	NA	NA
AZW02219.1\|28941_29145_-	hypothetical protein	NA	NA	NA	NA
AZW02390.1\|29190_29541_-	hypothetical protein	NA	NA	NA	NA
AZW02220.1\|29600_30200_-	hypothetical protein	A0A1V0E5L6	Salmonella_phage	1.7e-08	42.6
AZW02221.1\|30299_31244_-	hypothetical protein	NA	NA	NA	NA
AZW02222.1\|32345_33530_+	DNA-binding protein	NA	NA	NA	NA
AZW02223.1\|33595_33877_+	hypothetical protein	NA	NA	NA	NA
AZW02224.1\|34133_34340_+	hypothetical protein	NA	NA	NA	NA
AZW02225.1\|34460_34757_+	hypothetical protein	NA	NA	NA	NA
AZW02226.1\|34801_35239_+	hypothetical protein	NA	NA	NA	NA
AZW02227.1\|35306_35843_+	hypothetical protein	NA	NA	NA	NA
AZW02228.1\|36007_36376_+	hypothetical protein	NA	NA	NA	NA
AZW02229.1\|36808_37108_+	hypothetical protein	NA	NA	NA	NA
AZW02230.1\|37464_37749_+	hypothetical protein	NA	NA	NA	NA
AZW02231.1\|37814_38168_+	hypothetical protein	NA	NA	NA	NA
AZW02232.1\|38454_39186_-	NERD domain-containing protein	NA	NA	NA	NA
AZW02233.1\|39187_40369_-	S49 family peptidase	B8QTU8	Erwinia_phage	3.4e-13	29.2
AZW02234.1\|40379_41042_-	DUF4400 domain-containing protein	NA	NA	NA	NA
AZW02235.1\|41028_42138_-	hypothetical protein	NA	NA	NA	NA
AZW02236.1\|42137_44222_-	hypothetical protein	NA	NA	NA	NA
AZW02237.1\|44221_47368_-	helicase	NA	NA	NA	NA
AZW02238.1\|47377_48115_-	hypothetical protein	NA	NA	NA	NA
AZW02239.1\|48111_48597_-	plasmid transfer protein	NA	NA	NA	NA
AZW02240.1\|49354_50155_+	trhR	NA	NA	NA	NA
AZW02241.1\|50156_50669_+	hypothetical protein	NA	NA	NA	NA
AZW02242.1\|51261_52308_+	thioredoxin family protein	NA	NA	NA	NA
AZW02391.1\|52297_53713_+	conjugal transfer protein	NA	NA	NA	NA
AZW02243.1\|53721_57675_+	conjugal transfer protein TraG	NA	NA	NA	NA
AZW02244.1\|59251_59818_-	hypothetical protein	NA	NA	NA	NA
AZW02245.1\|59900_60440_-	lytic transglycosylase	NA	NA	NA	NA
AZW02246.1\|60587_61337_+	thiol:disulfide interchange protein	NA	NA	NA	NA
AZW02247.1\|61361_61754_+	hypothetical protein	NA	NA	NA	NA
AZW02248.1\|61787_62210_+	hypothetical protein	NA	NA	NA	NA
AZW02249.1\|62269_62881_-	hypothetical protein	NA	NA	NA	NA
AZW02250.1\|62987_63797_+	DsbA family protein	NA	NA	NA	NA
AZW02251.1\|64122_64827_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
AZW02252.1\|64913_65618_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AZW02253.1\|66505_67324_+	DUF4942 domain-containing protein	NA	NA	NA	NA
AZW02254.1\|67320_68526_+	ATP/GTP-binding protein	NA	NA	NA	NA
AZW02255.1\|68589_68793_-	hypothetical protein	NA	NA	NA	NA
AZW02256.1\|68805_70125_-	DUF1173 family protein	NA	NA	NA	NA
AZW02392.1\|70375_71803_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	3.4e-100	52.3
AZW02257.1\|72017_72533_+	thermonuclease family protein	A0A1X6WF84	Pacmanvirus	2.1e-07	38.6
AZW02393.1\|72535_73432_+	hypothetical protein	NA	NA	NA	NA
AZW02394.1\|73652_73886_+	hypothetical protein	NA	NA	NA	NA
AZW02258.1\|73931_74186_+	hypothetical protein	NA	NA	NA	NA
AZW02259.1\|74223_74511_+	hypothetical protein	NA	NA	NA	NA
AZW02260.1\|74547_74778_+	hypothetical protein	NA	NA	NA	NA
AZW02261.1\|75114_75576_+	hypothetical protein	NA	NA	NA	NA
AZW02262.1\|75605_76013_+	hypothetical protein	NA	NA	NA	NA
AZW02263.1\|76063_76357_-	hypothetical protein	NA	NA	NA	NA
AZW02264.1\|76756_77107_-	hypothetical protein	NA	NA	NA	NA
AZW02265.1\|78796_79501_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	3.4e-138	99.6
AZW02266.1\|79677_82686_+\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	62.8
AZW02395.1\|83318_83405_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
AZW02267.1\|88211_89072_-	class A broad-spectrum beta-lactamase TEM-135	Q1MVP3	Enterobacteria_phage	3.0e-160	99.7
AZW02268.1\|89254_89812_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
AZW02269.1\|90131_90836_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP034786

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP034784

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP034785

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection