CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP025580	Klebsiella pneumoniae strain 08EU827 plasmid p08EU827_4, complete sequence	0 crisprs	NA	0
CP025578	Klebsiella pneumoniae strain 08EU827 plasmid p08EU827_2, complete sequence	0 crisprs	NA	1
CP025577	Klebsiella pneumoniae strain 08EU827 plasmid p08EU827_1, complete sequence	0 crisprs	cas3,csa3,RT	2
CP025579	Klebsiella pneumoniae strain 08EU827 plasmid p08EU827_3, complete sequence	0 crisprs	NA	0
CP025576	Klebsiella pneumoniae strain 08EU827 chromosome, complete genome	2 crisprs	csa3,cas3,DEDDh,DinG,WYL	6

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 64665

Salmonella_phage(24.14%)

transposase,integrase

attL 1329:1343|attR 49328:49342

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ35154.1\|455_1292_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
AZZ35155.1\|1291_2095_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
1329:1343	attL	NA	NA	NA	NA
AZZ35156.1\|2155_2971_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
AZZ35157.1\|3300_3477_+\|integrase	integrase	T1S9J3	Salmonella_phage	1.0e-06	68.6
AZZ35158.1\|3658_4663_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AZZ35159.1\|4741_7708_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
AZZ35160.1\|7710_8271_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.1e-50	88.6
AZZ35161.1\|8401_8614_-	DUF3330 domain-containing protein	NA	NA	NA	NA
AZZ35162.1\|8668_9373_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6
AZZ35237.1\|9397_9910_+	restriction endonuclease	NA	NA	NA	NA
AZZ35163.1\|9914_10121_+	hypothetical protein	NA	NA	NA	NA
AZZ35164.1\|10502_11936_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
AZZ35165.1\|11969_13178_-	restriction endonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
AZZ35166.1\|13190_13403_-	resolvase	NA	NA	NA	NA
AZZ35167.1\|13444_14209_-\|transposase	IS6 family transposase IS6100	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AZZ35168.1\|14351_14618_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AZZ35169.1\|14838_15321_-	trimethoprim-resistant dihydrofolate reductase DfrA14	G3MBI7	Bacillus_virus	6.6e-16	28.9
AZZ35170.1\|15467_16481_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
AZZ35171.1\|16419_16734_+\|transposase	transposase	NA	NA	NA	NA
AZZ35172.1\|16873_17443_+	recombinase family protein	E5FFF9	Burkholderia_phage	5.2e-36	43.2
AZZ35173.1\|18199_19669_+	HNH endonuclease	G0X580	Salmonella_phage	5.5e-21	51.3
AZZ35174.1\|20188_20926_-	hypothetical protein	NA	NA	NA	NA
AZZ35175.1\|21063_21750_-	NYN domain-containing protein	NA	NA	NA	NA
AZZ35176.1\|22330_23272_-	hypothetical protein	NA	NA	NA	NA
AZZ35177.1\|23656_24361_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6
AZZ35178.1\|24306_24567_-	hypothetical protein	NA	NA	NA	NA
AZZ35179.1\|25112_25499_+	hypothetical protein	NA	NA	NA	NA
AZZ35180.1\|25507_25699_+	plasmid stabilization protein	NA	NA	NA	NA
AZZ35181.1\|26710_27466_+	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	4.5e-136	96.0
AZZ35182.1\|27466_27661_+	hypothetical protein	NA	NA	NA	NA
AZZ35183.1\|28144_28333_-	hypothetical protein	NA	NA	NA	NA
AZZ35184.1\|28883_29219_-	C2H2-type zinc finger protein	NA	NA	NA	NA
AZZ35185.1\|29391_29673_+	cytoplasmic protein	NA	NA	NA	NA
AZZ35186.1\|29726_30338_+	DUF2913 domain-containing protein	NA	NA	NA	NA
AZZ35187.1\|30486_31191_-\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AZZ35188.1\|32288_32540_-	hypothetical protein	NA	NA	NA	NA
AZZ35189.1\|32697_33129_+	peptidase	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
AZZ35190.1\|33128_34400_+	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	4.9e-151	63.3
AZZ35191.1\|34481_35459_-	chromosome partitioning protein ParB	Q38420	Escherichia_phage	2.6e-88	54.4
AZZ35192.1\|35455_36661_-	ParA family protein	A0A077SL49	Escherichia_phage	2.4e-163	69.6
AZZ35193.1\|37075_37345_+	hypothetical protein	NA	NA	NA	NA
AZZ35194.1\|37377_37575_-	hypothetical protein	NA	NA	NA	NA
AZZ35195.1\|37701_38568_-	RepB family plasmid replication initiator protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
AZZ35196.1\|39335_39593_+	hypothetical protein	NA	NA	NA	NA
AZZ35197.1\|39650_40427_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	6.4e-53	92.9
AZZ35198.1\|40423_41167_-	hypothetical protein	NA	NA	NA	NA
AZZ35199.1\|41217_41568_-	hypothetical protein	NA	NA	NA	NA
AZZ35200.1\|42192_44001_-	ATP-binding protein	NA	NA	NA	NA
AZZ35201.1\|43997_45044_-	hypothetical protein	NA	NA	NA	NA
AZZ35202.1\|46360_47542_+	DUF4268 domain-containing protein	NA	NA	NA	NA
AZZ35203.1\|48089_49094_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AZZ35204.1\|49172_52145_-\|transposase	Tn3-like element ISPa38 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
49328:49342	attR	NA	NA	NA	NA
AZZ35205.1\|52219_52510_+	nucleotidyltransferase	NA	NA	NA	NA
AZZ35206.1\|52506_52908_+	DUF86 domain-containing protein	NA	NA	NA	NA
AZZ35207.1\|52897_53254_+	cupin domain-containing protein	NA	NA	NA	NA
AZZ35208.1\|53508_53823_+	hypothetical protein	NA	NA	NA	NA
AZZ35209.1\|54249_55431_-	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	1.9e-120	64.2
AZZ35210.1\|56090_56696_-	DNA resolvase	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
AZZ35211.1\|56919_57780_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AZZ35212.1\|57962_58520_-	recombinase	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
AZZ35213.1\|59083_60346_+\|transposase	IS1380 family transposase ISEc9	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
AZZ35214.1\|60601_61477_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
AZZ35215.1\|61523_61856_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
AZZ35216.1\|61872_64665_+\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	99.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP025577

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8976 : 59298

Salmonella_phage(15.38%)

integrase,transposase

attL 46165:46184|attR 59334:59353

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ34955.1\|8976_9945_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	8.7e-185	98.4
AZZ34956.1\|9982_10234_-	DUF1471 domain-containing protein	A0A1B2IE60	Erwinia_phage	6.9e-09	59.6
AZZ34957.1\|10359_11151_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AZZ34958.1\|11299_12193_+	LysR family transcriptional regulator	NA	NA	NA	NA
AZZ34959.1\|12227_13217_-	aldo/keto reductase	NA	NA	NA	NA
AZZ34960.1\|13243_14095_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.4e-47	39.6
AZZ34961.1\|14564_15632_-	hypothetical protein	NA	NA	NA	NA
AZZ34962.1\|15862_16927_-	alpha/beta hydrolase	NA	NA	NA	NA
AZZ34963.1\|17034_17619_-	flavodoxin	NA	NA	NA	NA
AZZ34964.1\|17628_18390_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
AZZ34965.1\|18367_18847_-	cupin domain-containing protein	NA	NA	NA	NA
AZZ34966.1\|18911_20369_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.4e-21	27.6
AZZ34967.1\|20384_21065_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.0e-30	36.4
AZZ34968.1\|21079_22222_-	aldo/keto reductase	NA	NA	NA	NA
AZZ34969.1\|22496_23546_+	alpha/beta hydrolase	NA	NA	NA	NA
AZZ34970.1\|23805_24486_+	nitroreductase	M1I6Q5	Acanthocystis_turfacea_Chlorella_virus	1.9e-24	34.2
AZZ34971.1\|24493_25696_-	MFS transporter	NA	NA	NA	NA
AZZ34972.1\|26278_26509_-	hypothetical protein	NA	NA	NA	NA
AZZ35140.1\|26522_26696_-	transcriptional regulator	NA	NA	NA	NA
AZZ34973.1\|26723_27077_+	hypothetical protein	NA	NA	NA	NA
AZZ34974.1\|27258_28263_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AZZ34975.1\|28849_29932_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	6.8e-186	96.4
AZZ34976.1\|30053_33128_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.6
AZZ34977.1\|33179_34433_+	MFS transporter	NA	NA	NA	NA
AZZ34978.1\|34489_34660_+	galactoside O-acetyltransferase	NA	NA	NA	NA
AZZ34979.1\|35886_36891_+\|transposase	IS110 family transposase	NA	NA	NA	NA
AZZ35141.1\|37188_37431_+	hypothetical protein	NA	NA	NA	NA
AZZ34980.1\|37761_38055_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZDM8	Stx2-converting_phage	2.7e-49	96.9
AZZ34981.1\|38153_38921_-	ferric citrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2
AZZ34982.1\|38921_39878_-	iron-dicitrate transporter subunit FecD	NA	NA	NA	NA
AZZ34983.1\|39874_40873_-	iron-dicitrate transporter permease subunit	NA	NA	NA	NA
AZZ34984.1\|40869_41772_-	Fe(3+)-dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
AZZ34985.1\|41816_44141_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
AZZ34986.1\|44233_45187_-	FecR family protein	NA	NA	NA	NA
AZZ34987.1\|45183_45705_-	RNA polymerase subunit sigma	NA	NA	NA	NA
46165:46184	attL	NA	NA	NA	NA
AZZ34988.1\|46807_46975_+\|integrase	integrase	NA	NA	NA	NA
AZZ34989.1\|47259_48387_+	regulator	NA	NA	NA	NA
AZZ34990.1\|48383_48977_+	response regulator	NA	NA	NA	NA
AZZ34991.1\|48973_49822_+	ABC transporter permease	NA	NA	NA	NA
AZZ34992.1\|49821_50742_+	ABC transporter permease	NA	NA	NA	NA
AZZ34993.1\|50754_52359_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AZZ34994.1\|52403_53351_+	acetamidase	A0A1V0S8X7	Catovirus	9.6e-11	22.7
AZZ34995.1\|53358_55092_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.9e-15	29.6
AZZ34996.1\|55943_56204_-	hypothetical protein	NA	NA	NA	NA
AZZ34997.1\|57051_58056_-\|transposase	IS110 family transposase	NA	NA	NA	NA
AZZ34998.1\|58329_59298_+\|transposase	IS5/IS1182 family transposase	A0A1B0VFY5	Salmonella_phage	2.0e-173	91.6
59334:59353	attR	NA	NA	NA	NA

DBSCAN-SWA_2

96152 : 103992

Escherichia_phage(71.43%)

plate,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ35027.1\|96152_97442_-	arsenical efflux pump membrane protein ArsB	A0A2H4J144	uncultured_Caudovirales_phage	2.5e-171	73.5
AZZ35028.1\|97490_99242_-	arsenical pump-driving ATPase	NA	NA	NA	NA
AZZ35029.1\|99259_99622_-	arsenical resistance operon transcriptional repressor ArsD	NA	NA	NA	NA
AZZ35030.1\|99669_100023_-	transcriptional regulator	A0A2H4J145	uncultured_Caudovirales_phage	4.1e-23	50.0
AZZ35031.1\|100575_100932_+	recombination enhancement function domain protein	Q71TG3	Escherichia_phage	4.2e-36	65.2
AZZ35032.1\|100931_101162_+	hypothetical protein	NA	NA	NA	NA
AZZ35144.1\|101493_102015_+	maturation control protein	A0A222YZ79	Escherichia_phage	6.4e-49	53.8
AZZ35033.1\|102011_102341_+\|plate	baseplate protein	A0A222YYR0	Escherichia_phage	6.7e-36	65.1
AZZ35034.1\|102333_103536_+\|tail	phage tail protein	A0A222YXT1	Escherichia_phage	3.9e-126	63.6
AZZ35035.1\|103572_103992_-	transcriptional regulator	A0A222YXG1	Escherichia_phage	1.8e-06	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP025576

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CRISPR-Cas detection and classification

Crispr_ID: CP025576_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025576_1

1164731-1164839

Orphan

Consensus_repeat	Method
TGTCCCACCCTGTACCACTTTTTTTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025576_1

>merge|CP025576|1|1164731-1164839|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTTTAAACCAAATTCTGTAATGTGGGACGCTGAAACCCGCGCCAGCTCTGCGTGTACCACTTGTCCCACCCTGTACCACCTTTTTTTA

>CP025576|1|1|1164731-1164839|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTTTAA	ACCAAATTCTGTAATGTGGGACGCTGAAACCCGCGCCAGCTCTGCGTGTACCACT
TGTCCCACCCTGTACCACCTTTTTTTA

Protein	Signature genes	Signature genes Name	Protein_function
CP025576.1\|AZZ31068.1\|1158684_1159134_-\|phage-virion-morphogenesis-protein	unknown	unknown	gnl\|CDD\|368274
CP025576.1\|AZZ31070.1\|1160150_1160357_-\|hypothetical-protein	unknown	unknown	unknown
CP025576.1\|AZZ31072.1\|1161821_1162802_-\|PTS-sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
CP025576.1\|AZZ31073.1\|1162798_1163173_-\|PTS-sorbitol-transporter	unknown	unknown	gnl\|CDD\|226254
CP025576.1\|AZZ31081.1\|1172299_1173547_-\|DUF4102-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
CP025576.1\|AZZ31076.1\|1164182_1164539_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP025576.1\|AZZ31082.1\|1174219_1174702_-\|SsrA-binding-protein	unknown	unknown	gnl\|CDD\|235455
CP025576.1\|AZZ31080.1\|1171650_1172298_-\|hypothetical-protein	unknown	unknown	unknown
CP025576.1\|AZZ31079.1\|1167658_1171462_-\|DNA-binding-protein	unknown	unknown	unknown
CP025576.1\|AZZ31083.1\|1174812_1175289_+\|ubiquinone-binding-protein	unknown	unknown	gnl\|CDD\|182678
CP025576.1\|AZZ31075.1\|1163803_1164088_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|372675
CP025576.1\|AZZ31071.1\|1160797_1161811_-\|gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
CP025576.1\|AZZ31084.1\|1175278_1175569_+\|RnfH-family-protein	unknown	unknown	gnl\|CDD\|234982
CP025576.1\|AZZ31078.1\|1166962_1167178_-\|AlpA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225848
CP025576.1\|AZZ31069.1\|1159507_1159753_-\|holin	unknown	unknown	unknown
CP025576.1\|AZZ31085.1\|1175635_1175977_-\|outer-membrane-protein-assembly-factor-BamE	unknown	unknown	gnl\|CDD\|183190
CP025576.1\|AZZ31067.1\|1156749_1158108_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
CP025576.1\|AZZ31074.1\|1163169_1163691_-\|PTS-sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226253
CP025576.1\|AZZ31077.1\|1164857_1166927_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
CP025576.1\|AZZ31086.1\|1176124_1177786_-\|DNA-repair-protein-RecN	unknown	unknown	gnl\|CDD\|236781

Protein	Function_ID	Function_description	E-value
CP025576.1\|AZZ31068.1\|1158684_1159134_-\|phage-virion-morphogenesis-protein	gnl\|CDD\|368274	pfam05069, Phage_tail_S, Phage virion morphogenesis family. Protein S of phage P2 is thought to be involved in tail completion and stable head joining.	6.12186e-39
CP025576.1\|AZZ31072.1\|1161821_1162802_-\|PTS-sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	1.71362e-173
CP025576.1\|AZZ31073.1\|1162798_1163173_-\|PTS-sorbitol-transporter	gnl\|CDD\|226254	COG3731, SrlB, Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism].	3.73192e-58
CP025576.1\|AZZ31076.1\|1164182_1164539_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.98259e-09
CP025576.1\|AZZ31078.1\|1166962_1167178_-\|AlpA-family-transcriptional-regulator	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	5.83127e-21
CP025576.1\|AZZ31086.1\|1176124_1177786_-\|DNA-repair-protein-RecN	gnl\|CDD\|236781	PRK10869, PRK10869, recombination and repair protein; Provisional.	0
CP025576.1\|AZZ31083.1\|1174812_1175289_+\|ubiquinone-binding-protein	gnl\|CDD\|182678	PRK10724, PRK10724, type II toxin-antitoxin system RatA family toxin.	3.17506e-105
CP025576.1\|AZZ31075.1\|1163803_1164088_-\|transcriptional-regulator	gnl\|CDD\|372675	pfam13693, HTH_35, Winged helix-turn-helix DNA-binding.	1.06433e-37
CP025576.1\|AZZ31077.1\|1164857_1166927_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
CP025576.1\|AZZ31084.1\|1175278_1175569_+\|RnfH-family-protein	gnl\|CDD\|234982	PRK01777, PRK01777, RnfH family protein.	7.65271e-47
CP025576.1\|AZZ31082.1\|1174219_1174702_-\|SsrA-binding-protein	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	5.43734e-87
CP025576.1\|AZZ31085.1\|1175635_1175977_-\|outer-membrane-protein-assembly-factor-BamE	gnl\|CDD\|183190	PRK11548, PRK11548, outer membrane protein assembly factor BamE.	5.2573e-82
CP025576.1\|AZZ31067.1\|1156749_1158108_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	3.02794e-22
CP025576.1\|AZZ31074.1\|1163169_1163691_-\|PTS-sorbitol-transporter-subunit-IIC	gnl\|CDD\|226253	COG3730, SrlA, Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism].	8.84738e-79
CP025576.1\|AZZ31081.1\|1172299_1173547_-\|DUF4102-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	7.36952e-145
CP025576.1\|AZZ31071.1\|1160797_1161811_-\|gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.76512e-65

>CP025576.1|AZZ31076.1|1164182_1164539_+|XRE-family-transcriptional-regulator
MPEDGCCPERDNSCIFRCRVAIVIGKRLKISRVRADLTQAELGVLAGLDEESASARISSYEKEVHAPDFKLVCKLAAALDVPEAYFYAVDDELAELILQYHRFKKNNPGRTLLFSPNP
>CP025576.1|AZZ31075.1|1163803_1164088_-|transcriptional-regulator
MKKSTTKDWHPADIIAALHKRGTSLAKLSREAGLASSTLSNTLTRAWPKGEWLIAIALDVHPSEIWPGRYLNSSNKREPRKPLHPMTTTDNSGT
>CP025576.1|AZZ31074.1|1163169_1163691_-|PTS-sorbitol-transporter-subunit-IIC
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTIRMEKVAALLGRSRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYDDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSKRGNVP
>CP025576.1|AZZ31073.1|1162798_1163173_-|PTS-sorbitol-transporter
MMIYCARITAIGLFVADGLTDKMLITFDSNGPKDCLDYSLSLEPSFREESLMILPGDRLMLAGHDYLVTAVGKGAQQALFELGHLTLVFNGDLNPCHTGTVHLSGPVPNLRDLHGNLVIEEGRP
>CP025576.1|AZZ31072.1|1161821_1162802_-|PTS-sorbitol-transporter-subunit-IIB
MNTVLIPPGPGGYGKGLWLPVASGKKVLSLTGREIHPVAIEIGALTESEIVNGFSDIPPDNDILCVVINCAGSLRCGLYPQKGIPTINVLPTWRAGPLAHFITEENYVSDVTMEQLVLVDTAEAPDSEPEITPEPALRVITTPPPPRGAEKLVRMVEQTGTAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHAMTPLANSLWGLVLLSLICGIPFLSPVLGPGAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVIIGWLFSLGLF
>CP025576.1|AZZ31071.1|1160797_1161811_-|gfo/Idh/MocA-family-oxidoreductase
MNKIRAAVVGAGIYGKHHMNAYRHNPDTVLVAICDTDTERCDDLAMAYGVIGYTRLDVLLQEEAIDVVSVATPDPYHTESILTALRHGKHVLAEKPLATSVRECELIVEMAQQRDLLVGVDFHKRWDLAVMRIKAELEKPEAGRILRGHISMDDVISVPTEWLNWAGASSPVWFLGSHCFDLVRHLSGQEVVSVYAVGQKRLMVECGLDTFDSVQSLLTMADGSSWVVENSWVLPEGFPKDNDGRIDILCEATYIRSTSQHRGLEITTPGMTLTPNSYFINYRNGIASGFGIDPINDFVRAVRNRSPYPVTAVDGLAVSRICEAVHRSLKSGKPEKI
>CP025576.1|AZZ31070.1|1160150_1160357_-|hypothetical-protein
MESEHEAINIALTIENGVVTNVRQIRKDEHIASLETFLWIVKRAGYEVVPPQESTQDPENIKVLAEVE
>CP025576.1|AZZ31069.1|1159507_1159753_-|holin
MLCAGCTSAPPVPTPVIVYNACPRVSLCPMPGSDPTTNGDLSADIRQLVSALEGCALQVRTVKNCQDKIDVQAKESAKSLN
>CP025576.1|AZZ31068.1|1158684_1159134_-|phage-virion-morphogenesis-protein
MNDFKPFDDKLAGLIAALSPTARRKMAADIAKPLRARQQRRIKTQKAPDGTPYAARKRQPVKAKKDRVKREMFAKLRISRFMKATAGNDVAVVEFTGKVQRMVNVHQYGLKDKPSPNSGSVEYPARILLGFSPSDIDFASTKIVNYLSE
>CP025576.1|AZZ31067.1|1156749_1158108_-|adenylate/guanylate-cyclase-domain-containing-protein
MSTKNIYSNLEKSLEKTISESRSIRLRDSGYISEAASSSLAGMENLDSRYDFVKSSVALESVRADSNEQHYGITELVRHNFGKHGRLMPSFGCHPDFDNMDEGELRNGYSVTMFMDIIGSTKLGVIFSPETVFKIKNDIIRCAIETVNSFDGHVHRIMGDAVMAFFRSDKCEREGRIADSAIDALNCATYLIDMFKSTVIPKLNELGVDENLGIRIGIDYGAHDQVIWGKYGYMESQEVTATSFFVDVAAKLQQKAPKNSIMIGDSLAKLLGFDTNQLAVRTKIKNNEEVSLHYITPNYKDASGKSINYRQHLLKNESYYKLLPTGMLDSDFYIRASLKRDKNDPSDDNYISCSRVVRKGMGISFKGYYHSTITYDNPKFKFRVKNTGAEAADAENNGDHYFFEPAKYSDGRYFAPHWEDTKYKGLHHMYVSFWDGEQLIEPEKCFSVFIND
>CP025576.1|AZZ31077.1|1164857_1166927_-|DUF927-domain-containing-protein
MKRAPFLCKQSPDRTLEVVILAGSLAWETSRIWRKDPEREDDVPPVVLGPDELADLDNLTIIRPDTLYVRVLRTGDIREEELLKIAVKLAHAGVQMARLMSPDGELLEDWSGQLARLRQERPSDILPDHFRLDEEALWFDKLTERRDGESDVQPQRICSPLRVTAITCDSHDDSYGRLLEWHTTTGQLRRWAMPMAMLSGNGEELRRILLENGLTYISTRPALRSLLCEYISRSLPGRRVTCVEKTGWHNGVYVLPDEVIGPGGDNIILQGSHYLTGGFAQAGTLAEWQGQVAALCAGNSRLVFAVCCALAAPLLRLTGTGGGGFHLRGESTDGKTTVMKVAASVCGGTDYWHSWRATGNALEGIASRHNDALLPLDELREVDPREAGMIAYMLANGQGKGRARTDGEVRNRRHWTLLLFSTGELSLAEHTERAGERLYAGMDVRMVQIPSDTGNHGAFEQLHGFASGQQFADTLCDRVARFHGTAFRAWLAFLTHDQDASTTLARELLRRYQTALMPENAGNQVQRIVARFALLAVAGEMATLQGITGWQEGTAYGAVQICLHAWLNERGHIANQEDEGVLAQIKRFITAHQYSRFASWDGPDRPLNMVGFRRVEKDPLTGEEYTLFHILPEGWREMCRGFSPARAARLCLEAECLLPGSDGKYQSQVRLPEIGKARVYRLTSRILSI
>CP025576.1|AZZ31078.1|1166962_1167178_-|AlpA-family-transcriptional-regulator
MKTRADNNDAFPESGNVRMRQVVQFLAMSESSVYRLIKDTDFPRPVHLSSRLVVFDAAEIRQWQQRRAAIR
>CP025576.1|AZZ31079.1|1167658_1171462_-|DNA-binding-protein
MALLDKIKSLISANETATQNIEEESVYDTLTPKIITDSSVKHYFDALDFAFSKQDVKNIAITGPYGAGKSTVIQSYLKTHLNREFINVSLADFSLSGKSDEAPLENSEIELSILQQILYKENKDNLPDSRIDRIQNRNKKHISSLFLTVLSVVAPLLLLAITIFPKYFFSLFGATEPTINVIVNMFPERFFVSIIMGLLCLFFIVRVASKAGIFDKKIKLSKIAFLQGSADMASQESSSLLNNCLDEIVYFFSRSQYKIVVFEDLDRLGNAEVFVKLREINQIVNNNLQSEPVRFIYACRDDIFLGADIRTKFFDFILPVIPVMDARNAYTHLKNKLYDFPENEQPLLKQMSLYISDMRSLQNIVNEFNLFKKVVDDNTNQAKIFALIFYKNIYAQDYNLTDKKSGVLYSFIHNYRLRKLHENHFKLLDQRLEELNNKLVKIRKESVSTDAELRKQIISRFISPELWPIVYFIKDTGNYHQRYIKFSAESFYNSEHEFINYFEQNSSLYIGYPFNGNQHQLAKIDSTSIIEEYKQRNILISSNRDDAYKKTTKEIEELKENIRTRNAISLANLLKIIGWENFRTIAEEYIATCDDRTIIDPEQLETIRNGFRFGGFEALYYLLTNGYIMQDFMMFRSIFNQGTISANDNDYIKAVGRYIGCEEANQTFLLDNSKDVLAELVGQHYQYREGALHHQIIAFLLDSQDNQDHKTLSAMIAMIFRQPASVIIAIFKILEDRFINVDYFTRLVVSSLSENKYLDKMISVLKEQEHNAISKSIASKMIALVSPDISTDQKNYQKFIEDLGFSLVSEVEPNNLQYFLHNIEQLQVIYHDIYLPVTPNEMKALNFIGDHQMYPLDRATYRVVVAGLLQSDNVTCEMVDDLPWSLLDKHQLSKIKVYVNDNINIFVKDIFIDSKESSNAIVSVITHSDLSDELKILILEKMQFTVTGLNEFPEYIDVDGNELSYHDLFYRYDHVTPGWEALLAYICEECNLEILTQYIENYADVLSQEAINLMEGDRYDLLYMKVICNDNLSDSAYAAILEPVYINTHHWDERMSLKNLYRLIKNRKIELDPETFKQAIQYFISNNDLKRIEPFVLWFSQFKDNFFPNIEYYLCVNQDDVFFKESLIGINNSHVFTLQEKSSILFKCREHYELSLFEELTISNEGLIALVNTSTDDNFTIYVIIKLLKNGYRSRTEIAHFVSRLEEKEYTKIFYQKSATLNLDKPQEAELFLSALQQANLIKKWTLRDVGKYYVQCRYEEDESYLD
>CP025576.1|AZZ31080.1|1171650_1172298_-|hypothetical-protein
MTSPIRQNLFERECDMPLLEARHLALLLLGLDASQPANALPEEHQENYRILHDAISRTIKATGMVSAPANKRMFYADEMFALAWRLIDDELTPPEIKARSLKAVMKLSRNSRGRKWLKTLGDDALPDLTTSAQPSQRGMHKRDKARENTARLCWLLVQLLVEETDGRYGTSDKPASDRILRKLRALAQERELPSDGLGRGTFYEVLKMGRERKYR
>CP025576.1|AZZ31081.1|1172299_1173547_-|DUF4102-domain-containing-protein
MPKQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKVWHFEYYHPITKKRTKTSLGPYPVVTLAMARETRTQYRRLLYQGIDPRQHLAGIAEEKRIQTECTLEKVAGQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGSTPVTEIRPKMLKEHLTPLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLTLQNASIRKETRCLIEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLESALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQALLGEEEPLRIVEGE
>CP025576.1|AZZ31082.1|1174219_1174702_-|SsrA-binding-protein
MTKKKAHKPGSATIALNKRARHEYFIEDEYEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAFLFGANFTPMAVASTHYVCDPTRTRKLLLNQRELDTLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRTDLKDREWALDKARIMKHAGR
>CP025576.1|AZZ31083.1|1174812_1175289_+|ubiquinone-binding-protein
MILFALCLNVEPAMPQISRTALVPFSAEQMYQLVNDVKSYPDFLPGCTGSRVLEFGPTQMTAAVDVSKAGISKTFTTRNTLTSNQSILMSLVDGPFKKLIGGWKFIPLSPEACKIEFHLDFEFTNKLIEMAFGRVFKELAANMVQAFTSRAKEVYSAS
>CP025576.1|AZZ31084.1|1175278_1175569_+|RnfH-family-protein
MPANIRVEVAYALPEKQYLQRVTLDEGATVEQAIIASGLLALRDDIDLAKNKLGIYSRPVKLHDEVHDGDRVEIYRPLIADPKELRRQRAEKSAAK
>CP025576.1|AZZ31085.1|1175635_1175977_-|outer-membrane-protein-assembly-factor-BamE
MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLAPNDVAKIRVGMTQQQVAYALGTPMMTDPFGTNTWFYVFRQEPGHQKVTQQTLTLTFNSGGVLTNIDNKPALTSQ
>CP025576.1|AZZ31086.1|1176124_1177786_-|DNA-repair-protein-RecN
MLAQLTISNFAIVRELEIDFHSGMTAITGETGAGKSIAIDALGLCLGGRAEADMVRRGATRADLCARFALKDTPAAQRWLEENQLESGRECLLRRVISADGRSRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKTLLDGYTGEYALTQRMAEHYRQWHQSCRELAQHQQQSQERAARADLLQYQLKELNEFNPLPGEFEQIDEEYKRLANSGQLLSTCQHALTVLADGEEANLQSQLYTAKQLVSELVGMDSKLSGVLDMLEEAAIQLSEASDELRHYHDRLDLDPNRLFELEQRISRQIALARKHQVMPEELPAVYQAMLEEQRLLDDSAGSLESLSQQVVEHHQLALETARQLHALRQASADELTQLITESMHSLSMPHGVFAIEVAFDERHLTADGADHIEFRVTTNPGQPLQPIAKVASGGELSRIALAIQVITARKMETPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHHHFFVCKETDGEMTETHMQPLDKRARLQELARLLGGSEVTRNTLANAKELLAA

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Crispr_ID: CP025576_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025576_2

2077508-2077609

Orphan

Consensus_repeat	Method
TGTAGCCTCGCTAAGCGAAGCGCGAGCGATGAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025576_2

>merge|CP025576|2|2077508-2077609|CRISPRCasFinder
TGTAGCCTCGCTAAGCGAAGCGCGAGCGATGAGACAGCAGAACAGGTGGCTGAGAGAGTGCAGGAATGTGTAGCCTCGCTAAGCGAAGCGCGAGCGAGGAGA

>CP025576|2|2|2077508-2077609|CRISPRCasFinder
TGTAGCCTCGCTAAGCGAAGCGCGAGCGATGAGA	CAGCAGAACAGGTGGCTGAGAGAGTGCAGGAATG
TGTAGCCTCGCTAAGCGAAGCGCGAGCGAGGAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP025576.1\|AZZ31858.1\|2084950_2087626_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
CP025576.1\|AZZ31850.1\|2077010_2077454_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
CP025576.1\|AZZ31856.1\|2083216_2083624_-\|DNA-binding-transcriptional-regulator-H-NS	unknown	unknown	gnl\|CDD\|182858
CP025576.1\|AZZ31859.1\|2087703_2087889_+\|hypothetical-protein	unknown	unknown	unknown
CP025576.1\|AZZ31857.1\|2084185_2084803_+\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
CP025576.1\|AZZ31854.1\|2080981_2081995_+\|two-component-system-response-regulator-RssB	unknown	unknown	gnl\|CDD\|182652
CP025576.1\|AZZ31842.1\|2064805_2065456_-\|two-component-system-response-regulator-NarL	unknown	unknown	gnl\|CDD\|182619
CP025576.1\|AZZ31853.1\|2079989_2080892_+\|patatin-family-protein	unknown	unknown	gnl\|CDD\|182352
CP025576.1\|AZZ31847.1\|2074622_2075333_+\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl\|CDD\|185014
CP025576.1\|AZZ31845.1\|2069350_2073094_+\|nitrate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|227346
CP025576.1\|AZZ31851.1\|2078533_2079376_-\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
CP025576.1\|AZZ31849.1\|2076006_2076903_-\|EamA/RhaT-family-transporter	unknown	unknown	gnl\|CDD\|273359
CP025576.1\|AZZ31841.1\|2063426_2064809_+\|YchO-family-inverse-autotransporter-domain-containing-protein	unknown	unknown	gnl\|CDD\|236661
CP025576.1\|AZZ31855.1\|2082192_2083095_+\|UTP--glucose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|184021
CP025576.1\|AZZ31846.1\|2073090_2074626_+\|nitrate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|224063
CP025576.1\|AZZ31860.1\|2088102_2088750_+\|MarC-family-protein	unknown	unknown	gnl\|CDD\|236850
CP025576.1\|AZZ31848.1\|2075332_2076010_+\|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl\|CDD\|273030
CP025576.1\|AZZ31852.1\|2079418_2079889_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234966
CP025576.1\|AZZ31844.1\|2067556_2068945_+\|NarK-family-nitrate/nitrite-MFS-transporter	unknown	unknown	gnl\|CDD\|184994
CP025576.1\|AZZ31843.1\|2065466_2067245_-\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX	unknown	unknown	gnl\|CDD\|182581

Protein	Function_ID	Function_description	E-value
CP025576.1\|AZZ31858.1\|2084950_2087626_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
CP025576.1\|AZZ31850.1\|2077010_2077454_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.05574e-32
CP025576.1\|AZZ31856.1\|2083216_2083624_-\|DNA-binding-transcriptional-regulator-H-NS	gnl\|CDD\|182858	PRK10947, PRK10947, DNA-binding transcriptional regulator H-NS.	2.61324e-79
CP025576.1\|AZZ31857.1\|2084185_2084803_+\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	1.66434e-117
CP025576.1\|AZZ31854.1\|2080981_2081995_+\|two-component-system-response-regulator-RssB	gnl\|CDD\|182652	PRK10693, PRK10693, two-component system response regulator RssB.	0
CP025576.1\|AZZ31842.1\|2064805_2065456_-\|two-component-system-response-regulator-NarL	gnl\|CDD\|182619	PRK10651, PRK10651, transcriptional regulator NarL; Provisional.	1.26442e-140
CP025576.1\|AZZ31853.1\|2079989_2080892_+\|patatin-family-protein	gnl\|CDD\|182352	PRK10279, PRK10279, patatin-like phospholipase RssA.	0
CP025576.1\|AZZ31847.1\|2074622_2075333_+\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl\|CDD\|185014	PRK15054, PRK15054, nitrate reductase molybdenum cofactor assembly chaperone.	1.14838e-83
CP025576.1\|AZZ31845.1\|2069350_2073094_+\|nitrate-reductase-subunit-alpha	gnl\|CDD\|227346	COG5013, NarG, Nitrate reductase alpha subunit [Energy production and conversion].	0
CP025576.1\|AZZ31851.1\|2078533_2079376_-\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	4.09997e-176
CP025576.1\|AZZ31849.1\|2076006_2076903_-\|EamA/RhaT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	3.2204e-15
CP025576.1\|AZZ31841.1\|2063426_2064809_+\|YchO-family-inverse-autotransporter-domain-containing-protein	gnl\|CDD\|236661	PRK10177, PRK10177, YchO/YchP family invasin.	0
CP025576.1\|AZZ31855.1\|2082192_2083095_+\|UTP--glucose-1-phosphate-uridylyltransferase	gnl\|CDD\|184021	PRK13389, PRK13389, UTP--glucose-1-phosphate uridylyltransferase GalU.	0
CP025576.1\|AZZ31846.1\|2073090_2074626_+\|nitrate-reductase-subunit-beta	gnl\|CDD\|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
CP025576.1\|AZZ31860.1\|2088102_2088750_+\|MarC-family-protein	gnl\|CDD\|236850	PRK11111, PRK11111, YchE family NAAT transporter.	5.03226e-138
CP025576.1\|AZZ31848.1\|2075332_2076010_+\|respiratory-nitrate-reductase-subunit-gamma	gnl\|CDD\|273030	TIGR00351, Respiratory_nitrate_reductase_2_gamma_chain., respiratory nitrate reductase, gamma subunit. Involved in anerobic respiration the gene product catalyzes the reaction (reduced acceptor + NO3- = Acceptor + nitrite). Another possible role_id for this gene product is in nitrogen fixation (Role_id:160). [Energy metabolism, Anaerobic].	2.8765e-130
CP025576.1\|AZZ31852.1\|2079418_2079889_-\|hypothetical-protein	gnl\|CDD\|234966	PRK01617, PRK01617, hypothetical protein; Provisional.	3.29241e-106
CP025576.1\|AZZ31844.1\|2067556_2068945_+\|NarK-family-nitrate/nitrite-MFS-transporter	gnl\|CDD\|184994	PRK15034, PRK15034, nitrate/nitrite transport protein NarU; Provisional.	0
CP025576.1\|AZZ31843.1\|2065466_2067245_-\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX	gnl\|CDD\|182581	PRK10600, PRK10600, nitrate/nitrite two-component system sensor histidine kinase NarX.	0

>CP025576.1|AZZ31850.1|2077010_2077454_+|Lrp/AsnC-family-transcriptional-regulator
MNDVLDEIDRAILTCLTQDARVSLKVLSARVGLTSPSTAERVKRLEERGVIQGYGARVNLAALGYSLQALVRVRPLPGLLQKVDKYIQAMPECIESDKVTGEDCFVMRLVVRDIAQLDTLLDGLAEYAQCNTSVVKSSPVKRRLPPL
>CP025576.1|AZZ31849.1|2076006_2076903_-|EamA/RhaT-family-transporter
MQLTRGVWQMSLAMIISGSIGAFVLLSGLPVTDVVFWRCLIGALTLLVFIVLSRQPFSRLTRFTLALAVIGGAALVVNWLLLFAAYSRISIGMATVVYNTQPFMLVLMGMVLGERVSAVKWGWLLLAFGGVVILLSSELMPAHEEGLTTGVLLALGAAFFYALTAIIARKLHPLPAQHIAFIQVLVGVVMLLPLVHAPELTASFPWRYLLILGIVHTGIMYQLLYSAIQKLPTPVTGSLSFIYPLVAMVVDYLVFHHALSAVQLLGGMLILFAAAGNNLGWGEKKPRRGGVSEQSRAS
>CP025576.1|AZZ31848.1|2075332_2076010_+|respiratory-nitrate-reductase-subunit-gamma
MHFLNMFFFDIYPYIAGSVFLIGSWLRYDYGQYTWRAASSQMLDRKGMNLASNLFHIGILGIFAGHFLGMLTPHWMYESFLPIDVKQKMAMIAGGACGVMTLVGGLLLLKRRLLSPRVRATTTGADILILSLLMVQCALGLLTIPFSAQHMDGSEMMKLVGWAQSVVTFHGGASQHLDGVAFIFRVHLVLGMTLFLLFPFSRLVHIWSAPVEYLTRKYQIVRARR
>CP025576.1|AZZ31847.1|2074622_2075333_+|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MIELVIVSRLLEYPDAALWQHQQEMFEALASSEKLSKEDAHALGVFLRDLVAQDPLDAQAAYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLMAQYERHGLLLDSHELPDHLPLYLEYLAQLPEEEALGGLRDVAPILGLLSARLQQRESRYAVLFELLLKLANTQVDSQKVAEKIADEARDDTPQALDAVWEEEQVKFFADQGCGESEISAHQRRFAGAVAPQYLNISNGGQQ
>CP025576.1|AZZ31846.1|2073090_2074626_+|nitrate-reductase-subunit-beta
MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGMEYAWFNNVESKPGVGFPNDWENQEKWKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYEPFDYDYQNLHNAPESKHQPIARPRSLITGQRMDKITSGPNWEEILGGEFEKRAKDQNFDNMQKAMYGQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIESGMPTVCSETCVGRIRYLGVLLYDADAIENAASTENEKDLYQRQLDVFLDPNDPKVIEQALKDGVPQGVIEAAQQSPVYKMAMDWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLANLLTAGDTQPVLLALKRMLAMRHYKRAETVDGVVDTRALEEVGLSEAQAQEMYRYLAIANYEDRFVVPSSHREQAREAFPEKNGCGFSFGDGCHGSDSQFNLFNSRRIDAIDVTSKTEPHA
>CP025576.1|AZZ31845.1|2069350_2073094_+|nitrate-reductase-subunit-alpha
MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPLMRKRLMKMWREAKVQHSDPVEAWASIIEDADKAKSFKQARGRGGFVRSSWQEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAITPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDKPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRTLRASDLVDSLGQENNPEWKTVAFDEKGDMTVPNGSLGFRWGDKGKWNLEQRDGKTGEEIELRLSLLGSHDEVANVGFPYFGGEGSEHFNKVDLENILLHKLPAKRLQLADGSTALVTTVYDLTMANYGLERGLNDDNCAAGYDEVKAYTPAWAEKITGVSRAHIIRTAREFADNADKTHGRSMIIVGAGLNHWFHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAQELLSPMADKSRYSGHLIDFNVRAERMGWLPSAPQLGVNPLRIADEAKKAGMTPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEYMLKYLLGTENGIQGKDLGKQGGVKPEEVEWRDNGLDGKLDLVVTLDFRLSSTCLYSDIVLPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWESKSDWEIYKGIAKKFSEVCMGHLGKETDVVTLPIQHDSAAEMAQPLDVKDWKKGECDLIPGKTAPHIIPVERDYPATYERFTSIGPLLETIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPKLETAIDAAEMILTLAPETNGQVAVKAWQALSEITGREHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLTGRQSLYQDHQWMRDFGESLLVYRPPIDTRSVKAVMGEKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLSRGGPIVWMSEADAKDLGIEDNDWIEVFNANGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITGQRGGIHNSVTRITPKPTHMIGGYGHLAYGFNYYGTVGSNRDEFVVVRKMKNINWLDGEGNDQVQESVK
>CP025576.1|AZZ31844.1|2067556_2068945_+|NarK-family-nitrate/nitrite-MFS-transporter
MSQSSLPEKANRSVITDWRPEDPEFWQQRGHRVASRNLWISVPCLLLAFCVWMLFSAVAVNLNKVGFQFTTDQLFMLTALPALSGALLRVPYAFMVPLFGGRRWTAFSTGIMIVPCVWLGFAVQDTSTPFSIFVIISLLCGFAGANFASSMANISFFFPKAKQGGALGVNGGLGNMGVSVMQLVAPLVVSISIFAVFGGNGSEQPDGSMLYLENAAWIWVPFLIIFTLAAWFFMNDLSASKASLSEQLPVLKRLHLWIMALLYLATFGSFIGFSAGFAMLSKTQFPDVQILHYAFFGPFIGALARSMGGAISDRLGGTRVTLVNFVVMAVFCALLFLTLPTNGQGGNFIAFFAVFMVLFLTAGLGSASTFQMISVIFRKLTMDRVKAQGGSEAQAMREAATDTAAALGFISAIGAIGGFFIPKAFGISLDLTGSPAGAMKVFLVFYIACVVITWAVYGRKRQ
>CP025576.1|AZZ31843.1|2065466_2067245_-|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarX
MLKRLFTPLTLVNQLALIVLLATIIGVAGMAISARLVNGVQGSAHAINKAGSLRMQSYRLLAAIPLNENDQKLVADMTATVFSPELQNSARRDGQEIQLKALQQYWQLALAPGMQRAVNQAEVAQDVADFVDRIDQLVTAFDHTTEQRIERVVWIHRILAIGMALLLIFTIIWLRARLLRPWKQLLSMARAVSQRDFTQRAHISGRNEMATLGMALNNMSEELAESYAVLERRVQEKTAGLEQKNEILAFLWQANRRLHSSAPLCERISPVLNGLQGLTLLRDIEVRVYDLEDEDNHQEFTCHSDDDCDDKGCYLCPRNLPPLPDGGTTLKWRLSDAHSQYGILLATLPVGRHLSHDQQQLVDTLVEQLTSTLALDRHQEKQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPTESRQLLGQIRNELNTSWAQLRELLTTFRLQLTEPGLRPALEASCQEYSAHFGFTVQLDYQLPPRFVPSHQAIHLLQIAREALSNALKHASATEVTVTVSQRDNQVRLVVADNGRGVPDHAERSNHYGLIIMRDRAQSLRGDCQVRRRETGGTEVIVTFIPEKTFSIQ
>CP025576.1|AZZ31842.1|2064805_2065456_-|two-component-system-response-regulator-NarL
MSQQERATILLIDDHPMLRTGVKQLISMAPDIQVIGEASNGAQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRVVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATSDRDISQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
>CP025576.1|AZZ31841.1|2063426_2064809_+|YchO-family-inverse-autotransporter-domain-containing-protein
MAVSFRLLPTLTFLLLLPGVPVWALTASDTTRPAQAQDPLPDMGIAPQVDDDARHFAEVAKKFGEASMSDNGLTAGEQAQLFAISKIGNEVSHQLESWLSPWGNANVDLLVDKEGKFTGSKGSWFVPLQDNDRYLTWNQYSVTRREHDLVGNIGLGQRWRVGGWLLGYNSFYDKVLSESLARGSVGAEAWGEYLRLSANYYHPLGDWQLRDNQTQEQRMAAGYDVTAQARLPFYQHINTSVSVEQYFGDSVDLFHSGTGYHNPVAVSVGLNYTPVPLVTVTAKHKQGENGVSQNNVGLKLNYRFGVPLKQQLAADEVAISNSLRGSRFDSPERDNLPVVEYRQRKNLTVYLATPPWDLQSGETVQLKLQIHSLHGIKALHWQGDTQALSLTPPVDASSPDGWSIIMPVWNSEPGAANRWRLSVVVEDKQGQRVSSNEIALALTEPLVKFTTPGVSWTDSP
>CP025576.1|AZZ31851.1|2078533_2079376_-|formyltetrahydrofolate-deformylase
MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDATLLADLDSALPEGSIRELNPAGRRRVVILVTKEAHCLGDLLMKANYGGLDVDIAAVIGNHDTLRSLVERFGIPFELVSHEGLSREEHDQRMGDAIAAHEPDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYQVLAQRVFVYGNRTIIL
>CP025576.1|AZZ31852.1|2079418_2079889_-|hypothetical-protein
MEAVLSQLCPCGSALEYSSCCQRYLSGAELAPGPSQLMRSRYSAFVMKDADYLIKTWHPSCQAQQFRAELEKGFSQTEWLGLTLFASDEGRAPNEGFVSFVARFNDNNRPGAIIERSRFLKENGQWYYIDGTRPLIGRNDPCPCGSGKKFKKCCGQ
>CP025576.1|AZZ31853.1|2079989_2080892_+|patatin-family-protein
MRKLKIGLALGAGAARGWSHIGVINALQRAGIEIDIVAGCSIGSLVGAAYACNRLPALESWVCSFSNWDVLKLMDLSWRRGGLLRGEKVFNHYRRIMPVTEIERCERRFAAVATNLSTGRELWFTEGDLHLAIRASCSMPGLMSPVRHNGYWLVDGAVVNPVPVSLTRAMGADIVIAVDLQHDAHLMQQDLFSLETPRQEAEEKEGPWHTRLRARLTRMSSRRTAVTPTAMEIMTTSIQVLENRLKRNRMAGDPPDILLQPYCPQVSTLDFHRAGEAIAAGQLAVEKKMDELLPLVRTAV
>CP025576.1|AZZ31854.1|2080981_2081995_+|two-component-system-response-regulator-RssB
MTQPLAGKQILIVEDEPVFRSLLHGWLTSLGATTFQAEDGKDALHKMTEVHPDLMICDISMPRMNGLELVETLRNRGEQLPILMISATENMADIAKALRLGVQDVLLKPVKDFDRLRETVYACLYPAMFSSRVEEEERLFEDWDALVSNPIAASRLLQELQPPVQQEMSHCRIHYRQLVSADKPGLVLDIAPLSENDLAFYCLDVTRAGDNGVLAALLLRALFNGLLQEQLAHQGQRLPEMGSLLKQVNQLLRQANLPGQFPLLVGYYHSGLKNLILVSAGLNGTLNTGEHQIQISNGVPLGTLGDAYLNQISQRCTSWQCQIWGAGGRLRLMLSAE
>CP025576.1|AZZ31855.1|2082192_2083095_+|UTP--glucose-1-phosphate-uridylyltransferase
MAALNSKVRKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLEEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSRDNLAEMISRFDETGASQIMVEPVEDVTAYGVVDCKGESLKPGESVPMVGVVEKPKADVAPSNLAVVGRYVLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHKTLGDDFKAWLETAVAK
>CP025576.1|AZZ31856.1|2083216_2083624_-|DNA-binding-transcriptional-regulator-H-NS
MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEENAAAAEIEERTRKLQQYREMLIADGIDPNELLSTMAAVKAGTKTKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLI
>CP025576.1|AZZ31857.1|2084185_2084803_+|thymidine-kinase
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPARLYNPQTSLFDDIAAEHQLKPIHCVLVDESQFLTREQVHELSEVVDTLDIPVLCYGLRTDFRGELFTGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQEGRPYNEGEQVVIGGNERYVSVCRKHYKEALSVGSLTKVQNQHRPC
>CP025576.1|AZZ31858.1|2084950_2087626_-|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAVTNIAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKEATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFASHGGYLLQGKELKAVQDIILKNGALNAAIVGQPAAKIAELAGFTVPATTKILIGEVTNVDESEPFAHEKLSPTLAMYRAKDFEDAVAKAEKLVAMGGIGHTSCLYTDQDNQPARVAYFGQMMKTARILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLTIVRKGADLANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKRIYKFPKMGVKAKMVAITTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHALEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLESIKAELGIPKSIREAGVQEADFLAHVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGREFVEGEAGAKAEVAPVKAEKKAKKSA
>CP025576.1|AZZ31859.1|2087703_2087889_+|hypothetical-protein
MHVNVYVEKSGRCFTDLLKKLYLFRFQVLLPSTLLVSSRLLTSEYKLRDLDQVLSLLIPFS
>CP025576.1|AZZ31860.1|2088102_2088750_+|MarC-family-protein
MTQSLFDFSAYFKFFIGLFALVNPVGIIPVFISMTSYQPAAVRNKTNLTANLSVAIILLTSLFLGDGILQIFGISIDSFRIAGGILVVTIAMSMISGKLGEDKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSWVHLVGFSLAIAVFALCCWGIFRMAPWLVRLLGQTGINVITRIMGLLLMALGIEFIVTGIKALFPGLLS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1659363 : 1666268

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ34780.1\|1659363_1660227_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5
AZZ31499.1\|1660237_1661011_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	36.7
AZZ34781.1\|1661251_1662145_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
AZZ31500.1\|1662390_1663752_-	U32 family peptidase	Q6DW11	Phage_TP	1.8e-207	94.8
AZZ31501.1\|1664070_1664793_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
AZZ31502.1\|1664789_1666268_-	two-component system sensor histidine kinase BaeA	W8CYF6	Bacillus_phage	8.5e-30	28.3

DBSCAN-SWA_2

2701498 : 2712385

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ32440.1\|2701498_2704606_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
AZZ32441.1\|2704660_2705926_+	MFS transporter	NA	NA	NA	NA
AZZ32442.1\|2705956_2707045_-	chromosome segregation protein SMC	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
AZZ32443.1\|2707131_2707392_-	hypothetical protein	A0A077SK33	Escherichia_phage	5.4e-41	98.8
AZZ32444.1\|2707689_2708550_+	class A broad-spectrum beta-lactamase SHV-1	A0A077SL40	Escherichia_phage	4.4e-156	99.7
AZZ32445.1\|2708570_2709332_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
AZZ32446.1\|2709592_2710495_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
AZZ32447.1\|2710506_2711772_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	7.8e-234	99.8
AZZ32448.1\|2711764_2712385_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_3

3113335 : 3158219

Enterobacteria_phage(52.94%)

transposase,plate,integrase,tRNA,terminase,tail,capsid,portal

attL 3118563:3118580|attR 3154485:3154502

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ32802.1\|3113335_3113836_+\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
AZZ32803.1\|3113952_3114399_+	DUF441 domain-containing protein	NA	NA	NA	NA
AZZ34849.1\|3114382_3115174_-	AraC family transcriptional regulator	NA	NA	NA	NA
AZZ32804.1\|3115275_3116460_+	cyanate MFS transporter	NA	NA	NA	NA
AZZ32805.1\|3116491_3117184_-	hypothetical protein	NA	NA	NA	NA
AZZ32806.1\|3117329_3117839_+	DUF523 domain-containing protein	NA	NA	NA	NA
AZZ32807.1\|3117825_3118182_+	DUF488 domain-containing protein	NA	NA	NA	NA
AZZ32808.1\|3118171_3118411_-	DUF333 domain-containing protein	NA	NA	NA	NA
3118563:3118580	attL	NA	NA	NA	NA
AZZ32809.1\|3118675_3118927_-	hypothetical protein	A0A2I8TV89	Erwinia_phage	3.4e-08	49.2
AZZ32810.1\|3118970_3120110_-	hypothetical protein	B9A7A9	Serratia_phage	9.4e-146	71.0
AZZ32811.1\|3120264_3121437_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	2.9e-158	70.7
AZZ32812.1\|3121436_3121952_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	3.7e-57	61.2
AZZ32813.1\|3121997_3122315_+\|tail	phage tail protein	B9A7B2	Serratia_phage	1.0e-17	54.8
AZZ32814.1\|3122314_3122473_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	2.7e-11	65.3
AZZ32815.1\|3122459_3125435_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	1.1e-217	46.1
AZZ32816.1\|3125449_3125941_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	3.6e-54	61.5
AZZ32817.1\|3126231_3126612_-	hypothetical protein	NA	NA	NA	NA
AZZ32818.1\|3127013_3127982_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	3.7e-183	98.1
AZZ32819.1\|3127999_3128722_-	hypothetical protein	NA	NA	NA	NA
AZZ32820.1\|3129514_3130612_-\|tail	phage tail protein	G4KKN6	Yersinia_phage	5.2e-08	48.9
AZZ32821.1\|3130611_3130824_-	hypothetical protein	NA	NA	NA	NA
AZZ32822.1\|3130820_3133847_-\|tail	phage tail protein I	D5LGZ2	Escherichia_phage	4.1e-23	40.0
AZZ32823.1\|3133836_3134760_-\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	1.2e-53	44.6
AZZ32824.1\|3134761_3135112_-\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	1.6e-27	54.8
AZZ32825.1\|3135108_3135696_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	6.9e-60	60.5
AZZ32826.1\|3135692_3136328_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	4.6e-57	51.9
AZZ32827.1\|3136324_3136792_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	1.6e-46	59.5
AZZ34850.1\|3136973_3137303_-	DUF2570 domain-containing protein	NA	NA	NA	NA
AZZ32828.1\|3137314_3137860_-	lysozyme	Q1I0Z1	Pasteurella_virus	8.2e-31	42.5
AZZ32829.1\|3137856_3138141_-\|tail	phage tail protein	NA	NA	NA	NA
AZZ32830.1\|3138131_3138332_-\|tail	phage tail protein	A0A0A7NV57	Enterobacteria_phage	1.6e-16	63.1
AZZ32831.1\|3138331_3138847_-\|capsid	capsid assembly protein	A0A0A7NPU2	Enterobacteria_phage	4.1e-40	49.4
AZZ32832.1\|3138959_3139817_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	2.8e-70	61.3
AZZ32833.1\|3139866_3140901_-\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	1.4e-95	49.7
AZZ32834.1\|3140911_3141751_-\|capsid	phage capsid protein	A0A0A7NRY7	Enterobacteria_phage	1.2e-94	65.9
AZZ32835.1\|3141907_3143635_+	oxidoreductase	A0A0A7NV54	Enterobacteria_phage	3.1e-233	68.3
AZZ32836.1\|3143628_3144690_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	7.0e-143	68.4
AZZ32837.1\|3145209_3145824_-	hypothetical protein	NA	NA	NA	NA
AZZ32838.1\|3146979_3149589_-	replication endonuclease	A0A0M4RTM8	Salmonella_phage	2.2e-190	50.3
AZZ32839.1\|3149606_3150563_-	adenine methylase	A0A0M4QWR0	Salmonella_phage	6.6e-84	53.7
AZZ34851.1\|3150559_3150787_-	hypothetical protein	A0A286S1P6	Klebsiella_phage	1.9e-05	41.0
AZZ32840.1\|3150795_3151362_-	3'-5' exoribonuclease	D4HTX2	Vibrio_phage	1.0e-12	31.5
AZZ32841.1\|3151358_3151583_-	hypothetical protein	NA	NA	NA	NA
AZZ32842.1\|3151651_3151924_-	hypothetical protein	NA	NA	NA	NA
AZZ32843.1\|3151939_3152317_-	hypothetical protein	NA	NA	NA	NA
AZZ32844.1\|3152332_3152551_-	DUF4761 domain-containing protein	A0A0M5M1I3	Salmonella_phage	3.6e-06	49.1
AZZ32845.1\|3152571_3152850_-	hypothetical protein	Q1JS60	Enterobacteria_phage	6.2e-43	88.9
AZZ32846.1\|3152970_3153270_+	XRE family transcriptional regulator	Q1JS61	Enterobacteria_phage	6.5e-38	77.8
AZZ32847.1\|3153385_3154369_+\|integrase	integrase	Q83VS6	Escherichia_phage	6.4e-151	80.1
AZZ32848.1\|3154633_3155647_+	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.9e-12	29.0
3154485:3154502	attR	NA	NA	NA	NA
AZZ32849.1\|3155704_3155806_+	hypothetical protein	NA	NA	NA	NA
AZZ34852.1\|3155805_3155880_+	hypothetical protein	NA	NA	NA	NA
AZZ32850.1\|3155997_3156123_+	hypothetical protein	NA	NA	NA	NA
AZZ32851.1\|3156182_3156446_-	DUF2534 domain-containing protein	NA	NA	NA	NA
AZZ32852.1\|3156576_3157215_-	leucine efflux protein	NA	NA	NA	NA
AZZ32853.1\|3157304_3158219_-	lipid A biosynthesis palmitoleoyl acyltransferase	A0A1W6JP29	Morganella_phage	1.1e-72	50.4

DBSCAN-SWA_4

3177913 : 3228372

Enterobacteria_phage(23.68%)

integrase,tRNA,holin,terminase,protease,tail,portal

attL 3176069:3176083|attR 3226183:3226197

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3176069:3176083	attL	NA	NA	NA	NA
AZZ32876.1\|3177913_3178066_-	isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-18	92.0
AZZ32877.1\|3178220_3179717_-\|tail	phage tail protein	A0A0P0IDN1	Klebsiella_phage	1.4e-128	65.1
AZZ32878.1\|3179778_3188595_-	DUF1983 domain-containing protein	Q6UAW1	Klebsiella_phage	0.0e+00	43.2
AZZ32879.1\|3188657_3189248_-\|tail	tail assembly protein	K7PHE5	Enterobacteria_phage	2.5e-81	77.0
AZZ32880.1\|3189279_3189990_-	peptidase P60	Q6UAW4	Klebsiella_phage	1.1e-136	90.7
AZZ32881.1\|3189991_3190747_-\|tail	phage minor tail protein L	Q6UAW5	Klebsiella_phage	1.3e-130	84.1
AZZ32882.1\|3190743_3191091_-\|tail	phage tail protein	K7PJT2	Enterobacteria_phage	4.7e-40	67.8
AZZ32883.1\|3191095_3194239_-\|tail	phage tail tape measure protein	E4WL33	Enterobacteria_phage	0.0e+00	73.1
AZZ32884.1\|3194222_3194537_-\|tail	phage tail assembly protein T	E4WL32	Enterobacteria_phage	5.0e-41	75.0
AZZ32885.1\|3194557_3194986_-\|tail	phage minor tail protein G	M9NZD7	Enterobacteria_phage	2.7e-37	60.0
AZZ32886.1\|3194996_3195740_-\|tail	phage tail protein	K7PKX6	Enterobacterial_phage	1.7e-111	83.0
AZZ32887.1\|3195748_3196150_-\|tail	phage tail protein	K7PHM6	Enterobacterial_phage	2.7e-55	75.6
AZZ32888.1\|3196146_3196725_-\|tail	phage tail protein	K7PMB7	Enterobacterial_phage	1.7e-79	81.2
AZZ32889.1\|3196728_3197004_-	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	1.1e-23	57.1
AZZ32890.1\|3196996_3197323_-	DUF2190 domain-containing protein	K7PJY3	Enterobacterial_phage	8.1e-34	66.7
AZZ32891.1\|3197406_3199434_-\|protease	Clp protease ClpP	K7PKX4	Enterobacterial_phage	0.0e+00	82.1
AZZ32892.1\|3199378_3200881_-\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	2.8e-246	83.0
AZZ32893.1\|3200880_3201093_-	hypothetical protein	A5LH28	Enterobacteria_phage	2.9e-24	80.0
AZZ32894.1\|3201089_3203192_-\|terminase	phage terminase large subunit family protein	K7PH52	Enterobacterial_phage	0.0e+00	84.0
AZZ32895.1\|3203191_3203680_-	DUF1441 domain-containing protein	K7PJY2	Enterobacterial_phage	1.3e-72	87.7
AZZ32896.1\|3203911_3204334_-	hypothetical protein	Q6UAS0	Klebsiella_phage	1.2e-40	61.3
AZZ32897.1\|3204330_3204648_-	hypothetical protein	NA	NA	NA	NA
AZZ32898.1\|3205100_3205322_-	DNA gyrase subunit B	NA	NA	NA	NA
AZZ32899.1\|3205428_3205617_-	hypothetical protein	NA	NA	NA	NA
AZZ32900.1\|3206696_3207047_-	hypothetical protein	R9TPM9	Aeromonas_phage	1.8e-10	39.8
AZZ32901.1\|3207043_3207541_-	lysozyme	A0A1V0E5Q7	Salmonella_phage	1.9e-79	85.8
AZZ32902.1\|3207540_3207756_-\|holin	holin	A5LH82	Enterobacteria_phage	7.9e-30	87.3
AZZ32903.1\|3208973_3210005_+	nucleoid-associated protein	NA	NA	NA	NA
AZZ32904.1\|3209994_3211173_+	hypothetical protein	A0A291AUQ1	Sinorhizobium_phage	1.5e-45	29.9
AZZ32905.1\|3211196_3211544_-	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	5.5e-57	89.4
AZZ32906.1\|3211556_3212588_-	DUF968 domain-containing protein	S5MW46	Escherichia_phage	2.4e-95	49.3
AZZ32907.1\|3212587_3212791_-	hypothetical protein	NA	NA	NA	NA
AZZ32908.1\|3212787_3213180_-	DNA-binding protein	K7PHB4	Enterobacterial_phage	4.7e-12	36.6
AZZ32909.1\|3213220_3213511_-	hypothetical protein	H6WRY6	Salmonella_phage	1.4e-16	56.9
AZZ32910.1\|3213522_3213756_-	DinI family protein	K7PM44	Enterobacteria_phage	1.7e-25	71.1
AZZ32911.1\|3214218_3215586_-	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	9.0e-10	29.7
AZZ32912.1\|3215897_3216338_-	PerC family transcriptional regulator	NA	NA	NA	NA
AZZ32913.1\|3216351_3216816_-	replication protein	A0A0U2JGJ0	Escherichia_phage	7.6e-62	70.2
AZZ34853.1\|3216808_3217813_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	8.6e-34	41.9
AZZ32914.1\|3217873_3218428_-	hypothetical protein	NA	NA	NA	NA
AZZ32915.1\|3218430_3218655_-	Cro/Cl family transcriptional regulator	H6WRX5	Salmonella_phage	1.3e-19	62.5
AZZ32916.1\|3218743_3219181_+	helix-turn-helix domain-containing protein	H6WRX4	Salmonella_phage	1.3e-39	62.2
AZZ32917.1\|3219502_3219817_-	hypothetical protein	NA	NA	NA	NA
AZZ32918.1\|3219979_3220198_+	hypothetical protein	NA	NA	NA	NA
AZZ32919.1\|3220207_3220402_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AZZ32920.1\|3220444_3220789_+	transcriptional regulator	NA	NA	NA	NA
AZZ32921.1\|3220930_3223069_+	exonuclease	S4TNL0	Salmonella_phage	5.0e-100	43.0
AZZ32922.1\|3223121_3223367_+	excisionase	NA	NA	NA	NA
AZZ32923.1\|3223347_3224475_+\|integrase	integrase	O21925	Phage_21	3.3e-119	58.4
AZZ32924.1\|3224592_3225843_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.1e-19	92.6
AZZ32925.1\|3226083_3226734_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
3226183:3226197	attR	NA	NA	NA	NA
AZZ32926.1\|3226750_3227209_+	NUDIX hydrolase	NA	NA	NA	NA
AZZ34854.1\|3227265_3228372_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA

DBSCAN-SWA_5

3475469 : 3484943

Brazilian_cedratvirus(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ33143.1\|3475469_3477191_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
AZZ33144.1\|3477235_3477937_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AZZ33145.1\|3478290_3478509_+	translation initiation factor IF-1	NA	NA	NA	NA
AZZ33146.1\|3478639_3480919_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
AZZ33147.1\|3480949_3481267_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
AZZ33148.1\|3481592_3481814_+	cold shock domain protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
AZZ33149.1\|3481768_3481951_-	hypothetical protein	NA	NA	NA	NA
AZZ33150.1\|3481890_3483831_-	MacB family efflux pump subunit	G9BWD6	Planktothrix_phage	1.9e-37	40.5
AZZ33151.1\|3483827_3484943_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7

DBSCAN-SWA_6

4642107 : 4652082

Enterobacteria_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AZZ34168.1\|4642107_4644441_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	84.3
AZZ34169.1\|4644454_4644775_-	hypothetical protein	NA	NA	NA	NA
AZZ34170.1\|4644771_4644999_-	hypothetical protein	NA	NA	NA	NA
AZZ34171.1\|4644995_4645547_-	Ash-like/host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	3.4e-32	68.4
AZZ34172.1\|4646370_4647108_+	glycoprotein 3	Q7M2A2	Enterobacteria_phage	2.9e-71	60.1
AZZ34173.1\|4647104_4647350_+	hypothetical protein	Q7M294	Enterobacteria_phage	5.0e-20	59.3
AZZ34174.1\|4647367_4647934_+	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.1e-59	64.9
AZZ34175.1\|4648278_4650753_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
AZZ34176.1\|4650828_4652082_-	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	9.6e-75	41.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025578

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP025577

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP025576

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection