CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP035221	Enterococcus faecium strain SRCM103470 plasmid unnamed1	0 crisprs	cas14j,RT	0	3
CP035220	Enterococcus faecium strain SRCM103470 chromosome, complete genome	1 crisprs	cas1,cas2,csn2,DEDDh,cas3,csa3,DinG	4	6
CP035222	Enterococcus faecium strain SRCM103470 plasmid unnamed2	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5290 : 62710

Streptococcus_phage(27.78%)

integrase,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT24283.1\|5290_6250_+\|transposase	IS30-like element IS6770 family transposase	W5R8L2	Staphylococcus_phage	1.8e-36	35.9
QAT24284.1\|6523_6880_-	topoisomerase	NA	NA	NA	NA
QAT24489.1\|7779_7965_+	hypothetical protein	NA	NA	NA	NA
QAT24285.1\|8081_9507_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.9e-48	40.2
QAT24286.1\|9812_10775_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	3.0e-20	25.8
QAT24287.1\|10776_12216_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	1.8e-16	24.8
QAT24288.1\|12400_14347_+	PTS beta-glucoside transporter subunit IIBCA	NA	NA	NA	NA
QAT24289.1\|14610_15483_+	ROK family protein	NA	NA	NA	NA
QAT24290.1\|17803_18973_-\|transposase	IS256 family transposase	NA	NA	NA	NA
QAT24291.1\|19071_20355_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	4.6e-08	27.5
QAT24292.1\|20355_21045_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.9e-126	99.1
QAT24293.1\|21168_22290_-	class C sortase	NA	NA	NA	NA
QAT24294.1\|22286_23483_-	class C sortase	NA	NA	NA	NA
QAT24295.1\|23569_25057_-	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
QAT24296.1\|25121_25853_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
QAT24297.1\|25854_29514_-	VWA domain-containing protein	NA	NA	NA	NA
QAT24298.1\|30296_30977_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	9.4e-109	83.6
QAT24299.1\|31037_31589_+	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
QAT24300.1\|32288_33587_-	hypothetical protein	NA	NA	NA	NA
QAT24301.1\|33952_34861_+\|transposase	IS982 family transposase	NA	NA	NA	NA
QAT24302.1\|35323_36616_-	guanosine 5'-monophosphate oxidoreductase	NA	NA	NA	NA
QAT24490.1\|36590_37823_-	endonuclease	K4I1H4	Acidithiobacillus_phage	7.3e-19	36.1
QAT24303.1\|37993_38353_-	hypothetical protein	NA	NA	NA	NA
QAT24304.1\|38446_39133_+\|transposase	IS6-like element ISEnfa1 family transposase	A0A1X9I6C6	Streptococcus_phage	4.8e-113	88.5
QAT24305.1\|39828_40893_-	2,3-butanediol dehydrogenase	E3SJ82	Synechococcus_phage	7.2e-15	27.7
QAT24306.1\|41179_42385_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
QAT24307.1\|42402_43434_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
QAT24308.1\|43458_44427_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
QAT24309.1\|44443_45796_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	8.0e-43	30.2
QAT24310.1\|46148_47939_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
QAT24311.1\|48062_49364_-	DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	1.9e-105	99.0
QAT24312.1\|49363_49756_-	recombinase family protein	NA	NA	NA	NA
QAT24313.1\|50207_51347_-	MFS transporter	NA	NA	NA	NA
QAT24314.1\|51927_52518_-\|integrase	site-specific integrase	D2XR58	Bacillus_phage	8.3e-21	33.1
QAT24315.1\|52523_53357_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
QAT24316.1\|53537_54515_-	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
QAT24317.1\|54543_54810_-	hypothetical protein	A0A2H4PQP5	Staphylococcus_phage	6.2e-08	36.0
QAT24318.1\|55227_55587_-	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	4.4e-17	40.4
QAT24319.1\|55752_55950_+	DNA-binding protein	NA	NA	NA	NA
QAT24320.1\|55939_56554_+	XRE family transcriptional regulator	A0A139ZPI6	Marinitoga_camini_virus	5.5e-07	46.8
QAT24321.1\|56736_57654_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	4.6e-42	43.2
QAT24322.1\|57646_58396_+	ABC transporter permease	NA	NA	NA	NA
QAT24323.1\|58395_59226_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
QAT24324.1\|59651_60074_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
QAT24325.1\|61553_62710_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.8e-75	51.3

DBSCAN-SWA_2

79289 : 134505

Streptococcus_phage(27.27%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT24341.1\|79289_80198_-\|transposase	IS982-like element ISEfm1 family transposase	NA	NA	NA	NA
QAT24342.1\|80572_81532_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.6e-37	36.1
QAT24343.1\|82853_83171_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
QAT24344.1\|83171_83426_-	AbrB family transcriptional regulator	NA	NA	NA	NA
QAT24345.1\|83685_83826_-	addiction module toxin RelE	NA	NA	NA	NA
QAT24346.1\|85714_86755_+	replication protein RepA	NA	NA	NA	NA
QAT24347.1\|87578_87911_+	conjugal transfer protein TraE	NA	NA	NA	NA
QAT24348.1\|88529_88871_+	hypothetical protein	F0PIH7	Enterococcus_phage	3.1e-36	63.4
QAT24349.1\|88889_89180_+	hypothetical protein	NA	NA	NA	NA
QAT24350.1\|89371_89605_+	hypothetical protein	NA	NA	NA	NA
QAT24351.1\|89671_89911_+	hypothetical protein	NA	NA	NA	NA
QAT24352.1\|89996_90668_+	class A sortase	NA	NA	NA	NA
QAT24353.1\|90720_92349_+	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
QAT24354.1\|92857_93259_+\|transposase	IS200/IS605 family transposase	Q332K6	Clostridium_botulinum_C_phage	6.9e-43	62.4
QAT24355.1\|93282_94401_+\|transposase	transposase	A0A286QMQ9	Streptococcus_phage	1.1e-95	50.8
QAT24356.1\|94844_95600_+	class C sortase	NA	NA	NA	NA
QAT24357.1\|95596_96424_+	hypothetical protein	NA	NA	NA	NA
QAT24491.1\|96433_96682_+	hypothetical protein	NA	NA	NA	NA
QAT24358.1\|96712_98824_+	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
QAT24359.1\|98859_100911_-\|protease	serine protease	NA	NA	NA	NA
QAT24360.1\|101030_101240_-	hypothetical protein	NA	NA	NA	NA
QAT24361.1\|101427_101886_+	hypothetical protein	NA	NA	NA	NA
QAT24362.1\|101882_102125_+	hypothetical protein	NA	NA	NA	NA
QAT24363.1\|102142_102445_+	hypothetical protein	NA	NA	NA	NA
QAT24364.1\|102514_104569_+	hypothetical protein	NA	NA	NA	NA
QAT24365.1\|104568_107178_+	type IV secretory protein	NA	NA	NA	NA
QAT24366.1\|107174_109565_+	hypothetical protein	NA	NA	NA	NA
QAT24367.1\|109616_109949_+	hypothetical protein	NA	NA	NA	NA
QAT24368.1\|109949_110543_+	hypothetical protein	NA	NA	NA	NA
QAT24369.1\|110705_112400_+	ATPase	NA	NA	NA	NA
QAT24370.1\|112667_112901_+	hypothetical protein	NA	NA	NA	NA
QAT24371.1\|113087_114965_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.8e-29	26.4
QAT24372.1\|115472_116678_+	peptidase M23	Q6SEC2	Lactobacillus_prophage	2.5e-32	41.8
QAT24373.1\|116693_117338_+	hypothetical protein	NA	NA	NA	NA
QAT24374.1\|117348_118155_+	hypothetical protein	NA	NA	NA	NA
QAT24375.1\|118177_118408_+	hypothetical protein	NA	NA	NA	NA
QAT24376.1\|118922_119219_+	hypothetical protein	NA	NA	NA	NA
QAT24377.1\|119220_119643_+	hypothetical protein	NA	NA	NA	NA
QAT24378.1\|119661_121254_+	hypothetical protein	NA	NA	NA	NA
QAT24379.1\|121265_121601_+	hypothetical protein	NA	NA	NA	NA
QAT24380.1\|121746_121941_+	hypothetical protein	NA	NA	NA	NA
QAT24381.1\|121953_124326_+	hypothetical protein	B5SP25	Lactococcus_phage	9.8e-12	29.4
QAT24382.1\|124386_125847_+	hypothetical protein	NA	NA	NA	NA
QAT24492.1\|125857_128062_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	8.0e-117	51.0
QAT24383.1\|128307_128904_+	transcriptional regulator	NA	NA	NA	NA
QAT24384.1\|128916_129816_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
QAT24385.1\|129818_130304_+	single-stranded DNA-binding protein	Q938M7	Temperate_phage	5.4e-42	59.3
QAT24493.1\|130669_130930_+	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	4.5e-11	50.0
QAT24386.1\|131374_131581_+	DNA helicase UvrA	NA	NA	NA	NA
QAT24387.1\|131580_131832_+	hypothetical protein	NA	NA	NA	NA
QAT24388.1\|131847_132285_+	hypothetical protein	NA	NA	NA	NA
QAT24389.1\|132504_132705_+	hypothetical protein	NA	NA	NA	NA
QAT24390.1\|132965_133361_+	hypothetical protein	NA	NA	NA	NA
QAT24391.1\|133410_133617_+	hypothetical protein	NA	NA	NA	NA
QAT24392.1\|133818_134505_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	3.6e-124	97.3

DBSCAN-SWA_3

141806 : 193449

Bacillus_phage(30.0%)

integrase,holin,protease,transposase,bacteriocin

attL 157275:157300|attR 192208:192233

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT24400.1\|141806_142493_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	8.5e-126	98.2
QAT24401.1\|142698_142830_-\|bacteriocin	enterocin L50 family leaderless bacteriocin	NA	NA	NA	NA
QAT24402.1\|142849_142984_-\|bacteriocin	enterocin L50 family leaderless bacteriocin	NA	NA	NA	NA
QAT24403.1\|143491_143761_+	hypothetical protein	NA	NA	NA	NA
QAT24404.1\|143761_144034_+	hypothetical protein	NA	NA	NA	NA
QAT24405.1\|144023_144455_+	hypothetical protein	NA	NA	NA	NA
QAT24406.1\|144451_145834_+	hypothetical protein	NA	NA	NA	NA
QAT24407.1\|145835_146333_+	hypothetical protein	NA	NA	NA	NA
QAT24408.1\|146325_147543_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
QAT24409.1\|147539_148223_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.7e-38	38.7
QAT24410.1\|148219_149419_+	FtsX-like permease family protein	NA	NA	NA	NA
QAT24411.1\|149822_150167_-	hypothetical protein	NA	NA	NA	NA
QAT24412.1\|150247_150751_-	peptidase	A0A1B2APZ3	Phage_Wrath	3.4e-39	55.0
QAT24413.1\|150713_150950_+	XRE family transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	2.5e-13	52.1
QAT24414.1\|151186_153301_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	6.9e-118	38.7
QAT24415.1\|153682_153913_-	hypothetical protein	NA	NA	NA	NA
QAT24416.1\|153998_155124_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.9e-74	53.7
QAT24417.1\|155141_155738_+	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	3.3e-09	32.1
QAT24418.1\|155734_157165_-	hypothetical protein	NA	NA	NA	NA
157275:157300	attL	NA	NA	NA	NA
QAT24419.1\|157326_158511_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.9e-28	24.5
QAT24420.1\|158595_158814_-	hypothetical protein	NA	NA	NA	NA
QAT24421.1\|159980_160286_-	hypothetical protein	NA	NA	NA	NA
QAT24422.1\|160403_160664_-	hypothetical protein	NA	NA	NA	NA
QAT24423.1\|160800_161214_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
QAT24494.1\|162792_163335_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.2e-23	42.0
QAT24424.1\|163394_163691_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
QAT24425.1\|163749_164919_-\|transposase	IS256 family transposase	NA	NA	NA	NA
QAT24426.1\|165509_165932_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	2.4e-38	58.5
QAT24427.1\|166015_166669_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	5.8e-23	36.0
QAT24428.1\|166665_167430_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
QAT24429.1\|167504_167618_+	resolvase	NA	NA	NA	NA
QAT24430.1\|167831_168074_+	DUF302 domain-containing protein	NA	NA	NA	NA
QAT24431.1\|169402_170818_+	hypothetical protein	NA	NA	NA	NA
QAT24432.1\|171158_171293_+	DNA topoisomerase	NA	NA	NA	NA
QAT24433.1\|171532_172126_+	abortive infection protein	NA	NA	NA	NA
QAT24434.1\|172138_173038_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
QAT24435.1\|173040_173526_+	single-stranded DNA-binding protein	Q938M7	Temperate_phage	1.4e-42	60.5
QAT24436.1\|173602_173830_-\|holin	putative holin-like toxin	NA	NA	NA	NA
QAT24437.1\|173986_175177_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	6.2e-23	27.1
QAT24495.1\|175245_175509_+	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	6.5e-10	47.4
QAT24438.1\|176160_176412_+	hypothetical protein	NA	NA	NA	NA
QAT24439.1\|176427_176865_+	hypothetical protein	NA	NA	NA	NA
QAT24440.1\|177728_177929_+	hypothetical protein	NA	NA	NA	NA
QAT24441.1\|178144_178825_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	3.2e-109	83.6
QAT24442.1\|179200_184441_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
QAT24443.1\|184713_185307_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	7.1e-20	33.0
QAT24444.1\|185709_185967_-	hypothetical protein	A0A1P8CWQ3	Bacillus_phage	6.6e-07	52.9
QAT24445.1\|186032_187124_+	glycerol dehydrogenase	NA	NA	NA	NA
QAT24446.1\|187232_187493_+\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	1.4e-09	40.5
QAT24447.1\|187489_187981_+\|transposase	transposase	NA	NA	NA	NA
QAT24448.1\|188225_189461_+	mobilization protein	NA	NA	NA	NA
QAT24449.1\|190610_191297_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.2e-126	97.8
QAT24496.1\|191810_192176_+	hypothetical protein	NA	NA	NA	NA
QAT24450.1\|192258_193449_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	2.8e-23	27.1
192208:192233	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP035220

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP035220_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035220_1

299515-300012

TypeII-A

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRT

7 spacers

csn2,cas2,cas1

The CRISPR arrays of CP035220_1

>merge|CP035220|1|299515-300012|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTTTTCATGCCATCAGTATGTCGTTGATGCGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACCGTCATGTTCTACTACTACAGCACGTCCTTGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACACATGGTTAAGTTGTATAGCGGAGTAACTGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACATGGAAGCATTAGTGTTGATCGATTTCGCCGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACAAAAAATCGCTGGTAAGCTAGAAACTAGAGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTGCTTTTATGTCTTTGCCTTCTTTAAACTGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAGCATCTTTTTCCTACGATTTCTTTACCTGAAGGTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

>CP035220|1|1|299515-299946|PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTTTCATGCCATCAGTATGTCGTTGATGC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CGTCATGTTCTACTACTACAGCACGTCCTT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACATGGTTAAGTTGTATAGCGGAGTAACTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGGAAGCATTAGTGTTGATCGATTTCGCC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AAAAAATCGCTGGTAAGCTAGAAACTAGAG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TGCTTTTATGTCTTTGCCTTCTTTAAACTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAGC

>CP035220|1|1|299515-300012|CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTTTCATGCCATCAGTATGTCGTTGATGC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CGTCATGTTCTACTACTACAGCACGTCCTT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACATGGTTAAGTTGTATAGCGGAGTAACTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGGAAGCATTAGTGTTGATCGATTTCGCC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AAAAAATCGCTGGTAAGCTAGAAACTAGAG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TGCTTTTATGTCTTTGCCTTCTTTAAACTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAGC	ATCTTTTTCCTACGATTTCTTTACCTGAAG
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

>CP035220|1|1|299515-300012|CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTTTCATGCCATCAGTATGTCGTTGATGC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CGTCATGTTCTACTACTACAGCACGTCCTT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACATGGTTAAGTTGTATAGCGGAGTAACTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGGAAGCATTAGTGTTGATCGATTTCGCC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AAAAAATCGCTGGTAAGCTAGAAACTAGAG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TGCTTTTATGTCTTTGCCTTCTTTAAACTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAGC	ATCTTTTTCCTACGATTTCTTTACCTGAAG
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP035220.1\|QAT22019.1\|300544_300910_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
CP035220.1\|QAT22015.1\|293336_293534_+\|hypothetical-protein	unknown	unknown	unknown
CP035220.1\|QAT22016.1\|297564_298431_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP035220.1\|QAT24199.1\|298761_299424_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP035220.1\|QAT22013.1\|291140_292835_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
CP035220.1\|QAT22023.1\|307345_307708_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197
CP035220.1\|QAT22014.1\|292891_293020_-\|methanol-dehydrogenase	unknown	unknown	unknown
CP035220.1\|QAT22017.1\|298427_298772_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP035220.1\|QAT22018.1\|300182_300548_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
CP035220.1\|QAT22012.1\|289868_290729_+\|hypothetical-protein	unknown	unknown	unknown
CP035220.1\|QAT22009.1\|287912_288116_-\|hypothetical-protein	unknown	unknown	unknown
CP035220.1\|QAT22027.1\|311538_311838_+\|malonate-decarboxylase-subunit-delta	unknown	unknown	gnl\|CDD\|188283
CP035220.1\|QAT22025.1\|308872_309784_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|132175
CP035220.1\|QAT22026.1\|309790_311437_+\|malonate-decarboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|379906
CP035220.1\|QAT22010.1\|288099_288414_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372928
CP035220.1\|QAT22011.1\|288444_289578_-\|glutathione-dependent-formaldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|176243
CP035220.1\|QAT22020.1\|301070_302498_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|311953
CP035220.1\|QAT22024.1\|307895_308753_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP035220.1\|QAT22022.1\|305762_307202_-\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|375760
CP035220.1\|QAT22021.1\|303203_305756_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319775

Protein	Function_ID	Function_description	E-value
CP035220.1\|QAT22019.1\|300544_300910_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	8.2154e-25
CP035220.1\|QAT22023.1\|307345_307708_+\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.50194e-20
CP035220.1\|QAT24199.1\|298761_299424_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.01282e-107
CP035220.1\|QAT22013.1\|291140_292835_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
CP035220.1\|QAT22017.1\|298427_298772_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.51394e-45
CP035220.1\|QAT22018.1\|300182_300548_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	1.12042e-21
CP035220.1\|QAT22016.1\|297564_298431_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.91124e-120
CP035220.1\|QAT22027.1\|311538_311838_+\|malonate-decarboxylase-subunit-delta	gnl\|CDD\|188283	TIGR03130, malonate_delta, malonate decarboxylase acyl carrier protein. Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.	5.72696e-47
CP035220.1\|QAT22025.1\|308872_309784_+\|ACP-S-malonyltransferase	gnl\|CDD\|132175	TIGR03131, malonate_mdcH, malonate decarboxylase, epsilon subunit. Members of this protein family are the epsilon subunit of malonate decarboxylase. This subunit has malonyl-CoA/dephospho-CoA acyltransferase activity. Malonate decarboxylase may be a soluble enzyme, or linked to membrane subunits and active as a sodium pump. The epsilon subunit is closely related to the malonyl CoA-acyl carrier protein (ACP) transacylase family described by TIGR00128, but acts on an ACP subunit of malonate decarboxylase that has an unusual coenzyme A derivative as its prothetic group.	4.19278e-66
CP035220.1\|QAT22026.1\|309790_311437_+\|malonate-decarboxylase-subunit-alpha	gnl\|CDD\|379906	pfam16957, Mal_decarbox_Al, Malonate decarboxylase, alpha subunit, transporter. Mal_decarbox_Al is a family of Na+-transporting carboxylic acid decarboxylases.	0
CP035220.1\|QAT22010.1\|288099_288414_-\|hypothetical-protein	gnl\|CDD\|372928	pfam14145, YrhK, YrhK-like protein. The YrhK-like protein family includes the B. subtilis YrhK protein, which is functionally uncharacterized. Its expression is under the control of the motility sigma factor sigma-D. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 60 amino acids in length.	1.95591e-14
CP035220.1\|QAT22011.1\|288444_289578_-\|glutathione-dependent-formaldehyde-dehydrogenase	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	1.57106e-174
CP035220.1\|QAT22020.1\|301070_302498_-\|DNA-binding-protein	gnl\|CDD\|311953	pfam08280, HTH_Mga, M protein trans-acting positive regulator (MGA) HTH domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions.	0.00286938
CP035220.1\|QAT22024.1\|307895_308753_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.03447e-40
CP035220.1\|QAT22022.1\|305762_307202_-\|HTH-domain-containing-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	5.49729e-38
CP035220.1\|QAT22021.1\|303203_305756_+\|HAD-family-hydrolase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>CP035220.1|QAT24199.1|298761_299424_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLEQPLPLEKATFLIVEDVTVFAKVVKWFYQYSESHELKLFNDKYKELKESDLLIITDVLGFDINSASTLKLIYADLERQLNEKVEVKSMIDKLTATISELIGYELLDHELDLEGDEITVLELFKALGIKIETRSDTIFEKLLELLQVYKYLSKKKLLVLINVCSYLTEEEISEVQDYISLYHMEVLFVEPRSIKGIKQFVLDKDYFLNLENMV
>CP035220.1|QAT22017.1|298427_298772_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETADERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNPTASQAMLKRLKSNNPKKGFVTLLTVTEKQFARMVYLSGERDTSVANSDKRVIYLGEDEDAES
>CP035220.1|QAT22016.1|297564_298431_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNTHSKLAYVNNHLIFKNAEKTERLHLSEIDVLLLETTDITITTMLLKRLVDEKILVLFCDDKRLPVAKLLPFYSRHDSSLQLTRQLAWSPEKKGQVWTAIISQKIQNQSNFLQKQLFTEKAESIQELHEGLLEFDPTNREGHAARIYFQTLFGTKFTREENNEINAGLDYGYTLLLSMFAREIVKNGCMTQFGLKHANQFNDFNLASDFMEPFRPVIDEIVYRYRNCEFPVIKRRLFDLFTNKYSYGKKEMFLTNIVSDYTSKVIKVLNNETEGVPQFRI
>CP035220.1|QAT22015.1|293336_293534_+|hypothetical-protein
MILKSKAQKKRREQRCFKKADDGQSLILTCYIDLNATNIFIIAKITAFTIGVFVFSIMMSCWMKG
>CP035220.1|QAT22014.1|292891_293020_-|methanol-dehydrogenase
MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI
>CP035220.1|QAT22013.1|291140_292835_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAEEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLNNITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQEEEHVTVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSKVDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE
>CP035220.1|QAT22012.1|289868_290729_+|hypothetical-protein
MKQIQNKWNKRIIVMISSVCLFCLTVMLCLISTLANQHFMLEQNMQSDYAKKVAAEINQEIQSYHYEIGAPAEALEKIVSEELVQKNIELFIRNRYEKEPVELIGEKEVEEKLQEIINTYKQEEAEDDPFASEENNLLIYMTSGIFRRGIQSIYLMSFIDRILTIRERMVSFLPVISSILLVLLSGVFYLYRMSWKKVLWSFAVMIGGAGFQLLSLLVSLYLYDMTSQLDIRTQALQHLLDTYILSFIQFFSVVAIVEVVIAAGLWWIGKRVNTEKKVFSKRNEYK
>CP035220.1|QAT22011.1|288444_289578_-|glutathione-dependent-formaldehyde-dehydrogenase
MKAVTWQGKQKMEIRNVDDPRILEPTDAIIRITATAICGSDLHLYHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMESQCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNNLPDEKVLFLSDILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKAANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGTISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYEMIAEGLFDPTQIITHSLPLEEAAQAYEIFDKKEDKNIKVVLKP
>CP035220.1|QAT22010.1|288099_288414_-|hypothetical-protein
MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLLTGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKRTRKKHGKAV
>CP035220.1|QAT22009.1|287912_288116_-|hypothetical-protein
MGRPFSLLHAFLLFLCCAYFAYCDSKKFLSIEQFFGFLLYMLFHVPTLTAAFGTLAQEFLHYPEPSR
>CP035220.1|QAT22018.1|300182_300548_+|DUF1622-domain-containing-protein
MFNTQLIGYLEWIIAILNICSIGILIAGIVLVLFKLFDWSHVKKNYAERNARNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVISYFLNQEIEDKEKQRRGEVG
>CP035220.1|QAT22019.1|300544_300910_+|DUF1622-domain-containing-protein
MTTELMQFLLPYFEKLVLGLDIFAICLLIWGVCLSIKDFLKYLFVHTEAKNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIRTIISYFLNKEIGPVDVPNK
>CP035220.1|QAT22020.1|301070_302498_-|DNA-binding-protein
MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSYLLHVCKTTLLNDINNIKKEFEEQIVYTHREKDCYTLYFSEHIPRCKIMQQLTQNSLFLKTCLLYLEENEPDYLQLTECEFISVSKAYSLKKQVLAYFHDCGIEIDRYSPRFTEMERRLLLLNVAYRLGSFKSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQLCTVTIDPTFIEEIKKRPIYNYVESAWETTDFQTYYKKEEFAFILTLFNLCNYGCHSYQLIAEDFQQLHQVFIDNTPEIKELVATFETHFHQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTLFSSWAKRLPYDLRFNPNCMRAFVIELSGILRLTKERLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYASISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIERAIVSAVQNK
>CP035220.1|QAT22021.1|303203_305756_+|HAD-family-hydrolase
MNWYKLTVEDTLKNHQTSTEGLSQEERQKRLTDQGYNEIEARQQTKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEESLNGLKQLMGQEAIVLSNGMQVKIPAKELVKGDVIVLRAGYVVPADVRLIEVHDLLVEESILTGESEASEKNHSVLAAEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKINQALQSVEQQTTPLIKKINRLNKQIFQGILCLILFLVVFTTFRYGMDWHILLSAMIALVVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNEMTVVDVAAKEETRVLSIMKNCQELKTKEEQKIENLSGNPTELALIRHTETANLPLKKIEAKIPFSSEYKYMATMHTEEKGTVIYVKGAPEVLLAKSTLSYSEQEAWGQTATAFAKKGQRVLGFAYKKVDSKQELTHESLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKMITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSEEELTRQVPKVDVFARTTPEHKLRIVKALQKNGEIVGMTGDGVNDAPALKRADIGIAMGIKGSEVSKQAADMVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALILNRPLPLSPVQILWVNMVTTITLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVALLIMVPAYLLAMQFEGQSLQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKSLFLSLGILALLQGMVIFLPIGQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREFSR
>CP035220.1|QAT22022.1|305762_307202_-|HTH-domain-containing-protein
MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTERTIFSDLQSIRSHLPEGWDIFSDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLFTKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFYHRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKANCRLDSSIHISSTLSSLYDSALKKLYLKEGIYLKDTELSFASFCFLESWNYNNNYGQEIARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLVLKYHESPILIEPLERQYHRFLETYDQQYAHLYQQKENLLNDLKKEMEINEPNYFLQLLSLLIQQTIFSIKPNLFNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDSLDIPIVYISSIPTKNELNRLTELTFKTFL
>CP035220.1|QAT22023.1|307345_307708_+|hypothetical-protein
MLTEKELIDHIDETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVLMSVPEEKIYDDASDHRIIDILDLKVDPELGGILRGKEGYFPAYHMNKEHWISVDLRKIEKLDELAGLIDESFKSTQ
>CP035220.1|QAT22024.1|307895_308753_-|LysR-family-transcriptional-regulator
MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELGVPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK
>CP035220.1|QAT22025.1|308872_309784_+|ACP-S-malonyltransferase
MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENYQDTVFIQLALLTKAVFYLDEMERNGIQPDIVAGHSIGAFCAAVACRSLTFENAAELVYHRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSIEGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLFDARCLYIKNTDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKFGVDKGIRTINLDQHGIDDATFLYQKWR
>CP035220.1|QAT22026.1|309790_311437_+|malonate-decarboxylase-subunit-alpha
MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLIAPGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKIDFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNLYTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDKLPRVDIPGDWVDVVVKADQPYQLEALFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLKGKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSNRTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPAWQSLRNNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSEDTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDRLRDAGIVKLPEDLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS
>CP035220.1|QAT22027.1|311538_311838_+|malonate-decarboxylase-subunit-delta
MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKKESTVKICTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP035220_1	1.2\|299617\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299617-299646	30	KJ010489	Enterococcus phage IME-EFm1, complete genome	27249-27278	2	0.933
CP035220_1	1.2\|299617\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299617-299646	30	LC513943	Enterococcus phage vB_EfaS-DELF1 DNA, complete genome	21235-21264	3	0.9
CP035220_1	1.2\|299617\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299617-299646	30	MT119359	Enterococcus phage heks, complete genome	27870-27899	5	0.833
CP035220_1	1.2\|299617\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299617-299646	30	MK125140	Enterococcus phage Nonaheksakonda, complete genome	24429-24458	5	0.833
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NC_007713	Sodalis glossinidius str. 'morsitans' plasmid pSG1, complete sequence	3795-3824	5	0.833
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_LN854558	Sodalis glossinidius str. 'morsitans' isolate B4 plasmid pSG1, complete sequence	3794-3823	5	0.833
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NC_007182	Sodalis glossinidius pSG1 plasmid from Glossina austeni	57719-57748	5	0.833
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NC_007183	Sodalis glossinidius pSG1 plasmid from Glossina palpalis palpalis	57719-57748	5	0.833
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	MN642089	Klebsiella phage N1M2, complete genome	183123-183152	7	0.767
CP035220_1	1.7\|299947\|30\|CP035220\|CRISPRCasFinder,CRT	299947-299976	30	MT773555	Myoviridae sp. isolate BML_3 genomic sequence	53738-53767	7	0.767
CP035220_1	1.1\|299551\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299551-299580	30	MG945191	UNVERIFIED: Microviridae sp. isolate 696-1711, complete genome	855-884	8	0.733
CP035220_1	1.7\|299947\|30\|CP035220\|CRISPRCasFinder,CRT	299947-299976	30	NZ_CP013276	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-1-360K, complete sequence	185329-185358	8	0.733
CP035220_1	1.7\|299947\|30\|CP035220\|CRISPRCasFinder,CRT	299947-299976	30	NZ_CP039722	Bacillus thuringiensis strain BT-59 plasmid p1, complete sequence	322667-322696	8	0.733
CP035220_1	1.7\|299947\|30\|CP035220\|CRISPRCasFinder,CRT	299947-299976	30	NZ_CP009349	Bacillus thuringiensis HD1002 plasmid 1, complete sequence	261401-261430	8	0.733
CP035220_1	1.7\|299947\|30\|CP035220\|CRISPRCasFinder,CRT	299947-299976	30	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	164265-164294	8	0.733
CP035220_1	1.7\|299947\|30\|CP035220\|CRISPRCasFinder,CRT	299947-299976	30	NZ_CP045023	Bacillus thuringiensis strain JW-1 plasmid p1, complete sequence	185330-185359	8	0.733
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_CP048308	Escherichia coli strain 9 plasmid p009_D, complete sequence	24892-24921	9	0.7
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	674755-674784	9	0.7
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	441623-441652	9	0.7
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	441670-441699	9	0.7
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	713086-713115	9	0.7
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	16345-16374	9	0.7
CP035220_1	1.6\|299881\|30\|CP035220\|PILER-CR,CRISPRCasFinder,CRT	299881-299910	30	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	140046-140075	9	0.7

1. spacer 1.2|299617|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to KJ010489 (Enterococcus phage IME-EFm1, complete genome) position: , mismatch: 2, identity: 0.933

cgtcatgttctactactacagcacgtcctt	CRISPR spacer
cctcatgttctaccactacagcacgtcctt	Protospacer
* ***********.****************

2. spacer 1.2|299617|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to LC513943 (Enterococcus phage vB_EfaS-DELF1 DNA, complete genome) position: , mismatch: 3, identity: 0.9

cgtcatgttctactactacagcacgtcctt	CRISPR spacer
cctcatgttctacaactaccgcacgtcctt	Protospacer
* *********** ***** **********

3. spacer 1.2|299617|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to MT119359 (Enterococcus phage heks, complete genome) position: , mismatch: 5, identity: 0.833

cgtcatgttctactactacagcacgtcctt	CRISPR spacer
ctttgtgttctaccactactgcacgtcctt	Protospacer
* *..********.***** **********

4. spacer 1.2|299617|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to MK125140 (Enterococcus phage Nonaheksakonda, complete genome) position: , mismatch: 5, identity: 0.833

cgtcatgttctactactacagcacgtcctt	CRISPR spacer
ctttgtgttctaccactactgcacgtcctt	Protospacer
* *..********.***** **********

5. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NC_007713 (Sodalis glossinidius str. 'morsitans' plasmid pSG1, complete sequence) position: , mismatch: 5, identity: 0.833

tgcttttatgtctttgccttcttta--aactg	CRISPR spacer
ttcttttatggctttgtcttctttagtaac--	Protospacer
* ******** *****.********  ***

6. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN854558 (Sodalis glossinidius str. 'morsitans' isolate B4 plasmid pSG1, complete sequence) position: , mismatch: 5, identity: 0.833

tgcttttatgtctttgccttcttta--aactg	CRISPR spacer
ttcttttatggctttgtcttctttagtaac--	Protospacer
* ******** *****.********  ***

7. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NC_007182 (Sodalis glossinidius pSG1 plasmid from Glossina austeni) position: , mismatch: 5, identity: 0.833

tgcttttatgtctttgccttcttta--aactg	CRISPR spacer
ttcttttatggctttgtcttctttagtaac--	Protospacer
* ******** *****.********  ***

8. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NC_007183 (Sodalis glossinidius pSG1 plasmid from Glossina palpalis palpalis) position: , mismatch: 5, identity: 0.833

tgcttttatgtctttgccttcttta--aactg	CRISPR spacer
ttcttttatggctttgtcttctttagtaac--	Protospacer
* ******** *****.********  ***

9. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to MN642089 (Klebsiella phage N1M2, complete genome) position: , mismatch: 7, identity: 0.767

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
gactattatgtctttgcctactttactatg	Protospacer
 .** ************** *****   **

10. spacer 1.7|299947|30|CP035220|CRISPRCasFinder,CRT matches to MT773555 (Myoviridae sp. isolate BML_3 genomic sequence) position: , mismatch: 7, identity: 0.767

atctttttcctacgatttctttacctgaag	CRISPR spacer
ttctttttcctacgaattctctaccgtcaa	Protospacer
 ************** ****.****   *.

11. spacer 1.1|299551|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to MG945191 (UNVERIFIED: Microviridae sp. isolate 696-1711, complete genome) position: , mismatch: 8, identity: 0.733

tttttcatgccatcagtatgtcgttgatgc	CRISPR spacer
agttccatgccctcagtatgtcgttaacaa	Protospacer
  **.****** *************.*..

12. spacer 1.7|299947|30|CP035220|CRISPRCasFinder,CRT matches to NZ_CP013276 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-1-360K, complete sequence) position: , mismatch: 8, identity: 0.733

atctttttcctacgatttctttacctgaag	CRISPR spacer
atctttttcctactatttttttataaatat	Protospacer
************* ****.****.  . *

13. spacer 1.7|299947|30|CP035220|CRISPRCasFinder,CRT matches to NZ_CP039722 (Bacillus thuringiensis strain BT-59 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

atctttttcctacgatttctttacctgaag	CRISPR spacer
atctttttcctactatttttttataaatat	Protospacer
************* ****.****.  . *

14. spacer 1.7|299947|30|CP035220|CRISPRCasFinder,CRT matches to NZ_CP009349 (Bacillus thuringiensis HD1002 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

atctttttcctacgatttctttacctgaag	CRISPR spacer
atctttttcctactatttttttataaatat	Protospacer
************* ****.****.  . *

15. spacer 1.7|299947|30|CP035220|CRISPRCasFinder,CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

atctttttcctacgatttctttacctgaag	CRISPR spacer
atctttttcctactatttttttataaatat	Protospacer
************* ****.****.  . *

16. spacer 1.7|299947|30|CP035220|CRISPRCasFinder,CRT matches to NZ_CP045023 (Bacillus thuringiensis strain JW-1 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

atctttttcctacgatttctttacctgaag	CRISPR spacer
atctttttcctactatttttttataaatat	Protospacer
************* ****.****.  . *

17. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048308 (Escherichia coli strain 9 plasmid p009_D, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
cagttttttggctttgccttctttaatgat	Protospacer
.. **** ** ***************

18. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
atattttatttcttttccttctttaacagt	Protospacer
   ****** ***** **********

19. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
atattttatttcttttccttctttaacagt	Protospacer
   ****** ***** **********

20. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
atattttatttcttttccttctttaacagt	Protospacer
   ****** ***** **********

21. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
atattttatttcttttccttctttaacagt	Protospacer
   ****** ***** **********

22. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
atattttatttcttttccttctttaacagt	Protospacer
   ****** ***** **********

23. spacer 1.6|299881|30|CP035220|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttttatgtctttgccttctttaaactg	CRISPR spacer
atattttatttcttttccttctttaacagt	Protospacer
   ****** ***** **********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

946746 : 1026094

Enterococcus_phage(20.0%)

tail,holin,protease,portal,head,integrase,terminase,tRNA,transposase,capsid

attL 947659:947675|attR 1008855:1008871

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT22594.1\|946746_947508_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
QAT22595.1\|947643_947991_+	50S ribosomal protein L19	NA	NA	NA	NA
947659:947675	attL	NA	NA	NA	NA
QAT22596.1\|948122_949259_-\|integrase	site-specific integrase	A0A1P8BMN3	Lactococcus_phage	1.7e-54	36.8
QAT22597.1\|949382_949973_-	DUF4352 domain-containing protein	NA	NA	NA	NA
QAT22598.1\|950110_950764_-	hypothetical protein	NA	NA	NA	NA
QAT22599.1\|950813_951242_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
QAT22600.1\|951246_951621_-	XRE family transcriptional regulator	O03970	Lactobacillus_phage	3.2e-18	38.7
QAT22601.1\|951924_952110_+	XRE family transcriptional regulator	Q5YAA3	Bacillus_phage	1.1e-11	55.0
QAT22602.1\|952120_952369_+	hypothetical protein	NA	NA	NA	NA
QAT22603.1\|952727_953333_-	hypothetical protein	NA	NA	NA	NA
QAT22604.1\|953386_954085_+	phage regulatory protein	D2IYT0	Enterococcus_phage	2.1e-26	34.6
QAT22605.1\|954263_954605_+	hypothetical protein	NA	NA	NA	NA
QAT22606.1\|954597_955269_+	DUF1071 domain-containing protein	A0A1B1P7F0	Bacillus_phage	4.2e-29	47.4
QAT22607.1\|955274_955961_+	hypothetical protein	C9E2N1	Enterococcus_phage	1.7e-89	70.0
QAT22608.1\|955963_956713_+	helix-turn-helix domain-containing protein	A0A1L2BY83	Clostridium_phage	1.7e-31	54.0
QAT22609.1\|956724_956994_+	hypothetical protein	NA	NA	NA	NA
QAT22610.1\|957155_957461_+	hypothetical protein	NA	NA	NA	NA
QAT22611.1\|957744_957960_+	hypothetical protein	NA	NA	NA	NA
QAT22612.1\|957956_958256_+	hypothetical protein	NA	NA	NA	NA
QAT22613.1\|958245_958434_+	hypothetical protein	NA	NA	NA	NA
QAT22614.1\|958599_959067_+	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	3.8e-08	29.8
QAT22615.1\|959374_959893_-	hypothetical protein	A0A182BQC2	Lactococcus_phage	6.6e-22	35.7
QAT22616.1\|960443_960668_+	hypothetical protein	NA	NA	NA	NA
QAT22617.1\|960801_961656_+	hypothetical protein	C9E2Q0	Enterococcus_phage	3.9e-27	35.4
QAT22618.1\|961939_962134_+	hypothetical protein	NA	NA	NA	NA
QAT22619.1\|962130_962358_+	hypothetical protein	NA	NA	NA	NA
QAT22620.1\|962354_962642_+	hypothetical protein	NA	NA	NA	NA
QAT22621.1\|963171_963486_+	HNH endonuclease	A0A0K2CYS9	Paenibacillus_phage	2.6e-13	41.7
QAT22622.1\|963469_963709_+	hypothetical protein	NA	NA	NA	NA
QAT22623.1\|963983_964382_-	hypothetical protein	NA	NA	NA	NA
QAT22624.1\|964433_964952_+\|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	3.1e-11	27.7
QAT22625.1\|964942_966733_+\|terminase	terminase large subunit	A0A1B1P7R3	Bacillus_phage	2.7e-195	56.3
QAT22626.1\|966732_967968_+\|portal	phage portal protein	A0A0K2CZB0	Paenibacillus_phage	5.6e-120	57.1
QAT22627.1\|968002_968728_+\|protease	Clp protease ClpP	A0A0B5A796	Paenibacillus_phage	3.7e-71	57.8
QAT22628.1\|968728_969865_+\|capsid	phage major capsid protein	A0A0C5AEH1	Paenibacillus_phage	4.8e-134	65.9
QAT22629.1\|969938_970301_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
QAT22630.1\|970278_970641_+\|head,tail	phage head-tail adapter protein	A0A059T6F2	Listeria_phage	3.1e-26	54.3
QAT22631.1\|970633_971038_+	hypothetical protein	A0A2H4J7V9	uncultured_Caudovirales_phage	1.0e-17	37.7
QAT22632.1\|971034_971445_+	hypothetical protein	A0A059T681	Listeria_phage	1.1e-22	47.2
QAT22633.1\|971505_972093_+\|tail	phage tail protein	A0A2P0ZLF5	Lactobacillus_phage	2.7e-35	41.0
QAT22634.1\|972165_972633_+	Ig domain-containing protein	C9E2K1	Enterococcus_phage	8.1e-19	43.9
QAT22635.1\|972678_972987_+	hypothetical protein	NA	NA	NA	NA
QAT22636.1\|973181_979946_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	2.0e-17	38.4
QAT22637.1\|979949_980771_+\|tail	phage tail family protein	Q9T1A6	Listeria_phage	1.5e-55	43.0
QAT22638.1\|980779_981823_+	hypothetical protein	Q9T1A5	Listeria_phage	1.9e-105	55.3
QAT24223.1\|981822_982869_+	hypothetical protein	A0A0B5D0C2	Listeria_phage	2.8e-19	27.5
QAT24224.1\|982865_985163_+	DUF2479 domain-containing protein	A0A060AI60	Enterococcus_phage	2.6e-62	37.8
QAT22639.1\|985628_985757_+	XkdX family protein	NA	NA	NA	NA
QAT22640.1\|985817_986231_+\|holin	holin	A0A097BY69	Enterococcus_phage	2.3e-41	65.4
QAT22641.1\|986230_987205_+	N-acetylmuramoyl-L-alanine amidase	A0A060AHF9	Enterococcus_phage	6.6e-124	64.2
QAT22642.1\|987396_988878_-	hypothetical protein	NA	NA	NA	NA
QAT22643.1\|989213_989411_+	cold-shock protein	Q9AZD3	Lactococcus_phage	6.6e-23	76.9
QAT22644.1\|990424_990724_-	hypothetical protein	NA	NA	NA	NA
QAT22645.1\|990729_990960_-	hypothetical protein	NA	NA	NA	NA
QAT22646.1\|991460_991754_+	DUF2087 domain-containing protein	NA	NA	NA	NA
QAT22647.1\|991841_992498_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAT22648.1\|992746_993706_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.2e-10	26.8
QAT22649.1\|993911_995546_+	LPXTG-protein cell wall anchor protein	NA	NA	NA	NA
QAT24225.1\|995972_996233_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
QAT22650.1\|996229_996430_+	cell wall anchor protein	NA	NA	NA	NA
QAT24226.1\|996718_997732_+	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
QAT22651.1\|997728_999159_+	adhesin	NA	NA	NA	NA
QAT22652.1\|999647_1000784_+	class C sortase	NA	NA	NA	NA
QAT24227.1\|1000944_1001439_-	hypothetical protein	NA	NA	NA	NA
QAT22653.1\|1002027_1002450_+	HTH domain-containing protein	NA	NA	NA	NA
QAT22654.1\|1002615_1003809_-	MFS transporter	NA	NA	NA	NA
QAT24228.1\|1004005_1004377_+	hypothetical protein	NA	NA	NA	NA
QAT22655.1\|1004366_1005518_+	glucuronyl hydrolase	NA	NA	NA	NA
QAT22656.1\|1005546_1006806_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
QAT22657.1\|1006858_1007755_+	sugar ABC transporter permease	NA	NA	NA	NA
QAT22658.1\|1007765_1008635_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
QAT22659.1\|1008644_1009307_+	DUF624 domain-containing protein	NA	NA	NA	NA
1008855:1008871	attR	NA	NA	NA	NA
QAT22660.1\|1009512_1011177_+	acetolactate synthase AlsS	NA	NA	NA	NA
QAT22661.1\|1011189_1011900_+	acetolactate decarboxylase	NA	NA	NA	NA
QAT22662.1\|1012028_1012526_+	GAF domain-containing protein	NA	NA	NA	NA
QAT22663.1\|1012711_1012972_+	hypothetical protein	NA	NA	NA	NA
QAT22664.1\|1013383_1013920_-	VanZ family protein	NA	NA	NA	NA
QAT22665.1\|1015337_1016111_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
QAT22666.1\|1016254_1016605_+	SdpI family protein	NA	NA	NA	NA
QAT22667.1\|1016585_1017302_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.1e-34	36.2
QAT22668.1\|1017301_1018750_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	1.0e-19	29.3
QAT22669.1\|1018818_1019778_-\|transposase	IS30 family transposase	NA	NA	NA	NA
QAT22670.1\|1019888_1020398_-	hypothetical protein	NA	NA	NA	NA
QAT22671.1\|1020387_1021113_-	FtsX-like permease family protein	NA	NA	NA	NA
QAT22672.1\|1021284_1023405_-	LTA synthase family protein	W6LM83	Streptococcus_phage	5.7e-221	58.4
QAT22673.1\|1023633_1024812_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	2.1e-103	49.7
QAT22674.1\|1024827_1025586_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	2.5e-25	35.6
QAT22675.1\|1025608_1026094_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA

DBSCAN-SWA_2

1568889 : 1577950

Synechococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT23164.1\|1568889_1569468_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-26	37.4
QAT24246.1\|1569464_1570508_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.3e-61	43.9
QAT23165.1\|1570539_1571979_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.1e-53	33.3
QAT23166.1\|1571963_1574186_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.8e-151	41.4
QAT23167.1\|1574186_1574858_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
QAT23168.1\|1574859_1575114_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
QAT23169.1\|1575113_1575842_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	5.1e-44	42.2
QAT23170.1\|1576097_1576475_+	hypothetical protein	NA	NA	NA	NA
QAT23171.1\|1576654_1577950_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	33.1

DBSCAN-SWA_3

1846138 : 1940182

104

Enterococcus_phage(23.91%)

tail,holin,head,protease,portal,integrase,terminase,transposase,tRNA,capsid

attL 1863226:1863242|attR 1925793:1925809

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT23413.1\|1846138_1847086_-	NAD-dependent epimerase/dehydratase family protein	A0A1V0SKV4	Klosneuvirus	4.3e-51	37.2
QAT23414.1\|1847124_1847670_-	hypothetical protein	NA	NA	NA	NA
QAT23415.1\|1847741_1848629_-	hypothetical protein	U3PJ04	Lactobacillus_phage	1.5e-18	38.0
QAT23416.1\|1848822_1849623_+\|transposase	IS30 family transposase	NA	NA	NA	NA
QAT23417.1\|1849684_1850422_-	AAA family ATPase	A0A059NT77	Lactococcus_phage	1.4e-62	51.2
QAT23418.1\|1850390_1851650_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	5.2e-105	49.5
QAT23419.1\|1852267_1852666_-	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	4.4e-18	39.3
QAT23420.1\|1852680_1853502_-	LicD family protein	A0A1V0SAS8	Catovirus	6.6e-08	36.5
QAT23421.1\|1853515_1854931_-	O-antigen ligase domain-containing protein	NA	NA	NA	NA
QAT23422.1\|1854930_1856061_-	glycosyltransferase	NA	NA	NA	NA
QAT23423.1\|1856060_1857593_-	transporter	NA	NA	NA	NA
QAT23424.1\|1857630_1858596_-	glycosyltransferase	A0A0F7L2F7	uncultured_marine_virus	5.6e-06	33.0
QAT23425.1\|1858588_1859656_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
QAT23426.1\|1859663_1860365_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
QAT23427.1\|1860361_1861234_-	LicD family protein	NA	NA	NA	NA
QAT23428.1\|1861413_1862454_-	glycosyltransferase family 2 protein	A8CG95	Salmonella_phage	3.9e-05	31.5
QAT23429.1\|1862473_1863865_-	sugar transferase	NA	NA	NA	NA
1863226:1863242	attL	NA	NA	NA	NA
QAT23430.1\|1864157_1866296_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
QAT23431.1\|1866334_1867921_-	methyltransferase domain-containing protein	NA	NA	NA	NA
QAT23432.1\|1867910_1869131_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-11	26.9
QAT23433.1\|1869142_1869949_-	ABC transporter permease	NA	NA	NA	NA
QAT23434.1\|1870157_1871438_-	hypothetical protein	NA	NA	NA	NA
QAT23435.1\|1871481_1873515_-	hypothetical protein	NA	NA	NA	NA
QAT23436.1\|1873549_1874401_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.9e-38	38.6
QAT23437.1\|1874498_1875527_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	6.4e-69	42.9
QAT23438.1\|1875548_1876121_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	4.1e-41	48.6
QAT23439.1\|1876134_1877001_-	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	2.2e-102	62.5
QAT23440.1\|1877100_1877835_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
QAT23441.1\|1877812_1878640_-	glycosyltransferase	NA	NA	NA	NA
QAT23442.1\|1878639_1879440_-	glycosyltransferase	NA	NA	NA	NA
QAT23443.1\|1879432_1880572_-	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
QAT23444.1\|1880647_1881571_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
QAT23445.1\|1881602_1882367_-	type I methionyl aminopeptidase	NA	NA	NA	NA
QAT23446.1\|1882524_1882965_+	flavodoxin	NA	NA	NA	NA
QAT23447.1\|1883140_1883710_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
QAT23448.1\|1883965_1885198_+	aminopeptidase	NA	NA	NA	NA
QAT24254.1\|1885209_1885404_-	hypothetical protein	NA	NA	NA	NA
QAT23449.1\|1885345_1885894_-	hypothetical protein	NA	NA	NA	NA
QAT23450.1\|1886729_1887032_+	hypothetical protein	NA	NA	NA	NA
QAT23451.1\|1888041_1888239_-	cold-shock protein	Q9AZD3	Lactococcus_phage	3.9e-23	78.5
QAT23452.1\|1888659_1889352_-	hypothetical protein	NA	NA	NA	NA
QAT23453.1\|1889479_1890490_-	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	3.1e-60	65.2
QAT23454.1\|1890500_1890698_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	7.8e-24	85.9
QAT23455.1\|1890713_1890956_-\|holin	holin	D2J075	Enterococcus_phage	2.1e-23	68.4
QAT23456.1\|1891019_1893896_-	hypothetical protein	A0A0S2MYI4	Enterococcus_phage	1.2e-96	52.9
QAT23457.1\|1893919_1896211_-	hypothetical protein	A0A1D3SNL1	Enterococcus_phage	1.6e-88	29.8
QAT23458.1\|1896220_1896958_-\|tail	phage tail protein	NA	NA	NA	NA
QAT23459.1\|1897008_1900440_-\|tail	phage tail tape measure protein	A0A1D3SNL5	Enterococcus_phage	3.3e-77	41.3
QAT23460.1\|1900456_1900639_-	hypothetical protein	NA	NA	NA	NA
QAT23461.1\|1900641_1901004_-	hypothetical protein	NA	NA	NA	NA
QAT23462.1\|1901025_1901631_-\|tail	phage tail protein	Q8W5Z9	Listeria_phage	6.7e-34	41.2
QAT23463.1\|1901642_1902047_-	hypothetical protein	R4IBU7	Listeria_phage	6.1e-07	29.5
QAT23464.1\|1902039_1902441_-	hypothetical protein	A0A1B1P759	Bacillus_phage	3.0e-14	34.1
QAT23465.1\|1902430_1902784_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
QAT23466.1\|1902773_1903085_-	hypothetical protein	A0A1B1P751	Bacillus_phage	1.1e-11	43.5
QAT23467.1\|1903081_1903957_-	hypothetical protein	D2IYX3	Enterococcus_phage	1.9e-130	74.2
QAT23468.1\|1903966_1905127_-\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	9.4e-101	50.4
QAT23469.1\|1905126_1905813_-\|protease	Clp protease ClpP	A0A2I6PDD0	Staphylococcus_phage	1.8e-30	39.7
QAT23470.1\|1905775_1906954_-\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	3.2e-80	40.4
QAT23471.1\|1906973_1908668_-\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	1.8e-148	49.8
QAT23472.1\|1908645_1908960_-\|terminase	terminase	A0A1S7FYW6	Listeria_phage	3.3e-08	37.9
QAT23473.1\|1909062_1909344_-	hypothetical protein	NA	NA	NA	NA
QAT23474.1\|1909348_1909693_-	HNH endonuclease	A0A1B1P757	Bacillus_phage	1.0e-26	58.1
QAT23475.1\|1909942_1910497_-	hypothetical protein	A0A1Q1PW40	Staphylococcus_phage	5.8e-16	34.2
QAT23476.1\|1910516_1911461_-	hypothetical protein	NA	NA	NA	NA
QAT24255.1\|1911855_1912272_-	autolysin	C9E2P5	Enterococcus_phage	1.4e-46	67.4
QAT23477.1\|1912400_1912595_-	hypothetical protein	NA	NA	NA	NA
QAT23478.1\|1912591_1912948_-	hypothetical protein	A8E2C9	Enterococcus_phage	2.1e-11	35.6
QAT23479.1\|1913098_1913407_-	hypothetical protein	NA	NA	NA	NA
QAT23480.1\|1913403_1913601_-	hypothetical protein	NA	NA	NA	NA
QAT23481.1\|1913626_1913845_-	phosphocarrier protein HPr domain protein	NA	NA	NA	NA
QAT23482.1\|1913841_1914153_-	hypothetical protein	A0A0D3MVS9	Staphylococcus_phage	3.5e-26	57.0
QAT23483.1\|1914152_1914458_-	hypothetical protein	NA	NA	NA	NA
QAT23484.1\|1914454_1914616_-	antitoxin	NA	NA	NA	NA
QAT23485.1\|1914612_1914915_-	hypothetical protein	NA	NA	NA	NA
QAT23486.1\|1915077_1915347_-	hypothetical protein	NA	NA	NA	NA
QAT23487.1\|1915358_1916108_-	helix-turn-helix domain-containing protein	A0A1L2BY83	Clostridium_phage	1.7e-31	54.0
QAT23488.1\|1916110_1916797_-	hypothetical protein	C9E2N1	Enterococcus_phage	3.2e-88	69.1
QAT23489.1\|1916802_1917474_-	DUF1071 domain-containing protein	A0A1B1P7F0	Bacillus_phage	5.5e-29	47.4
QAT23490.1\|1917466_1917808_-	hypothetical protein	NA	NA	NA	NA
QAT23491.1\|1917986_1918712_-	phage regulatory protein	D2IYT0	Enterococcus_phage	3.3e-27	35.5
QAT23492.1\|1918764_1919241_+	hypothetical protein	NA	NA	NA	NA
QAT23493.1\|1919432_1919753_-	DUF771 domain-containing protein	NA	NA	NA	NA
QAT23494.1\|1919765_1919951_-	XRE family transcriptional regulator	Q5YAA3	Bacillus_phage	1.1e-11	55.0
QAT23495.1\|1920253_1920628_+	XRE family transcriptional regulator	O03970	Lactobacillus_phage	3.2e-18	38.7
QAT23496.1\|1920632_1921061_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
QAT23497.1\|1921145_1921607_+	DUF4429 domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	7.7e-06	33.3
QAT23498.1\|1921640_1922276_+	DUF3221 domain-containing protein	NA	NA	NA	NA
QAT23499.1\|1922385_1923525_+\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	2.0e-95	47.1
QAT23500.1\|1924055_1925237_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
QAT23501.1\|1925360_1925774_-	DUF3284 domain-containing protein	NA	NA	NA	NA
QAT23502.1\|1925773_1925956_-	DUF3188 domain-containing protein	NA	NA	NA	NA
1925793:1925809	attR	NA	NA	NA	NA
QAT23503.1\|1925987_1926209_-	hypothetical protein	NA	NA	NA	NA
QAT23504.1\|1926278_1927739_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
QAT23505.1\|1927846_1928167_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
QAT23506.1\|1928195_1928513_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
QAT23507.1\|1928665_1931368_-	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
QAT23508.1\|1931430_1932708_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.2e-34	28.5
QAT23509.1\|1932707_1933721_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
QAT23510.1\|1933736_1934465_-	DNA/RNA nuclease SfsA	NA	NA	NA	NA
QAT24256.1\|1934641_1934971_+	DUF4828 domain-containing protein	NA	NA	NA	NA
QAT23511.1\|1935146_1935794_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
QAT23512.1\|1935808_1937335_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	8.9e-75	35.3
QAT23513.1\|1937383_1940182_-\|tRNA	isoleucine--tRNA ligase	A0A2H4UVG0	Bodo_saltans_virus	7.4e-75	26.4

DBSCAN-SWA_4

1975335 : 2014286

Enterococcus_phage(53.85%)

tail,holin,head,portal,integrase,terminase,capsid

attL 1975123:1975158|attR 2014378:2014413

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1975123:1975158	attL	NA	NA	NA	NA
QAT23548.1\|1975335_1976130_+	DUF4428 domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	3.3e-12	32.9
QAT23549.1\|1976223_1976526_+	hypothetical protein	NA	NA	NA	NA
QAT23550.1\|1977365_1977545_+	hypothetical protein	NA	NA	NA	NA
QAT23551.1\|1977557_1978115_+	GNAT family N-acetyltransferase	A0A0B5CYP1	Listeria_phage	9.3e-30	41.5
QAT23552.1\|1978158_1979184_-	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	4.5e-62	55.2
QAT23553.1\|1979194_1979392_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	3.0e-23	85.9
QAT23554.1\|1979407_1979650_-\|holin	holin	D2J075	Enterococcus_phage	2.0e-21	62.0
QAT23555.1\|1979684_1979822_-	XkdX family protein	NA	NA	NA	NA
QAT23556.1\|1979823_1980270_-	hypothetical protein	NA	NA	NA	NA
QAT23557.1\|1980270_1982358_-	DUF2479 domain-containing protein	A0A0M4RT83	Enterococcus_phage	1.4e-62	41.3
QAT23558.1\|1982357_1983140_-	hypothetical protein	NA	NA	NA	NA
QAT23559.1\|1983156_1984914_-	DUF2479 domain-containing protein	Q9AZX4	Lactococcus_phage	2.5e-36	42.3
QAT23560.1\|1984888_1987720_-	peptidase M23	A0A1P8BMB8	Lactococcus_phage	0.0e+00	60.3
QAT24258.1\|1987716_1988484_-\|tail	phage tail protein	D7RWD9	Brochothrix_phage	1.5e-59	45.1
QAT23561.1\|1988516_1991231_-	tape measure protein	A0A1P8BMG6	Lactococcus_phage	4.1e-06	27.0
QAT23562.1\|1991247_1991547_-	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	2.9e-22	58.3
QAT23563.1\|1991600_1991951_-	hypothetical protein	Q77RZ7	Lactococcus_phage	1.5e-30	57.8
QAT23564.1\|1991994_1992507_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	2.0e-55	65.5
QAT23565.1\|1992507_1992903_-\|capsid	phage capsid protein	Q77K20	Lactococcus_phage	1.3e-38	59.8
QAT23566.1\|1992903_1993287_-	hypothetical protein	A0A097BY98	Enterococcus_phage	3.1e-45	73.4
QAT23567.1\|1993279_1993597_-	hypothetical protein	C9E2J7	Enterococcus_phage	2.7e-34	66.3
QAT23568.1\|1993593_1993923_-	hypothetical protein	A0A0S2MYD5	Enterococcus_phage	6.4e-39	75.5
QAT23569.1\|1993934_1994198_-	hypothetical protein	D2J062	Enterococcus_phage	6.5e-10	75.0
QAT23570.1\|1994215_1995139_-\|capsid	phage major capsid protein	A0A1B1V000	Enterococcus_phage	1.1e-139	77.5
QAT23571.1\|1995151_1995754_-	DUF4355 domain-containing protein	A0A097BY91	Enterococcus_phage	3.2e-36	51.5
QAT23572.1\|1995880_1996807_-\|head	phage head morphogenesis protein	A0A1L2JXH2	Streptococcus_phage	3.4e-93	58.6
QAT23573.1\|1996811_1998311_-\|portal	phage portal protein	A0A097BY86	Enterococcus_phage	6.2e-222	78.7
QAT23574.1\|1998323_1999568_-\|terminase	PBSX family phage terminase large subunit	D2IYW1	Enterococcus_phage	1.5e-200	81.2
QAT23575.1\|1999554_2000088_-\|terminase	terminase small subunit	A0A059NT97	Lactococcus_phage	9.2e-19	40.7
QAT23576.1\|2000114_2000339_-	hypothetical protein	NA	NA	NA	NA
QAT24259.1\|2001172_2001589_-	autolysin	C9E2P5	Enterococcus_phage	6.2e-47	68.1
QAT23577.1\|2001664_2001961_-	hypothetical protein	NA	NA	NA	NA
QAT23578.1\|2001960_2002167_-	hypothetical protein	NA	NA	NA	NA
QAT23579.1\|2002163_2002361_-	hypothetical protein	NA	NA	NA	NA
QAT23580.1\|2002851_2003049_-	DUF1642 domain-containing protein	NA	NA	NA	NA
QAT23581.1\|2003050_2003518_-	DUF1642 domain-containing protein	A0A0C5JZC6	Enterococcus_phage	6.2e-27	68.4
QAT24260.1\|2003514_2003583_-	hypothetical protein	NA	NA	NA	NA
QAT24261.1\|2003667_2004420_-	site-specific DNA-methyltransferase	A0A097QQ03	Enterococcus_phage	4.1e-121	82.2
QAT23582.1\|2004461_2004644_-	hypothetical protein	NA	NA	NA	NA
QAT23583.1\|2004640_2004958_-	DUF1140 family protein	A0A2H4JAZ4	uncultured_Caudovirales_phage	3.5e-10	36.4
QAT23584.1\|2004957_2005248_-	hypothetical protein	D2IZR3	Enterococcus_phage	4.8e-14	44.4
QAT23585.1\|2005241_2005547_-	hypothetical protein	NA	NA	NA	NA
QAT23586.1\|2005549_2005711_-	antitoxin	NA	NA	NA	NA
QAT23587.1\|2005725_2006085_-	DUF1064 domain-containing protein	A0A1P8BKR1	Lactococcus_phage	1.1e-18	48.3
QAT23588.1\|2006081_2006933_-	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.2e-25	28.7
QAT23589.1\|2006949_2007780_-	replication protein	C9E2N2	Enterococcus_phage	2.6e-52	45.2
QAT23590.1\|2007782_2008469_-	hypothetical protein	C9E2N1	Enterococcus_phage	1.3e-89	70.5
QAT23591.1\|2008474_2009221_-	DUF1071 domain-containing protein	A0A1X9IGE5	Lactococcus_phage	1.7e-42	47.5
QAT23592.1\|2009213_2009555_-	hypothetical protein	NA	NA	NA	NA
QAT23593.1\|2009877_2010066_-	hypothetical protein	D2IZW5	Enterococcus_phage	3.1e-06	56.9
QAT23594.1\|2010086_2010371_-	hypothetical protein	NA	NA	NA	NA
QAT23595.1\|2010361_2010568_-	XRE family transcriptional regulator	D2IZW2	Enterococcus_phage	4.3e-09	54.5
QAT23596.1\|2010564_2011338_-	phage antirepressor	B2ZYU5	Staphylococcus_phage	3.8e-66	52.4
QAT23597.1\|2011982_2012330_+	XRE family transcriptional regulator	A0A097QQ00	Enterococcus_phage	9.2e-28	62.5
QAT24262.1\|2012365_2012761_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
QAT23598.1\|2012814_2013126_+	hypothetical protein	NA	NA	NA	NA
QAT23599.1\|2013137_2014286_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	3.0e-67	40.1
2014378:2014413	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2034238 : 2042832

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT23620.1\|2034238_2036428_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.2e-284	66.4
QAT23621.1\|2036864_2037467_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	4.9e-53	58.0
QAT23622.1\|2037520_2038642_-	DNA polymerase IV	NA	NA	NA	NA
QAT23623.1\|2038750_2039623_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.6e-89	60.1
QAT23624.1\|2039691_2040039_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	5.1e-18	41.1
QAT23625.1\|2040031_2040856_-	signal peptidase	NA	NA	NA	NA
QAT23626.1\|2040891_2041830_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.8e-34	33.8
QAT23627.1\|2041843_2042173_-	hypothetical protein	NA	NA	NA	NA
QAT23628.1\|2042187_2042832_-	dTMP kinase	M1PSC7	Streptococcus_phage	4.2e-58	52.6

DBSCAN-SWA_6

2230156 : 2313563

Enterococcus_phage(33.33%)

tail,holin,protease,head,portal,integrase,terminase,transposase,capsid

attL 2273120:2273179|attR 2310435:2310495

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT23793.1\|2230156_2231116_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.2e-10	26.8
QAT23794.1\|2231310_2231745_-	hypothetical protein	NA	NA	NA	NA
QAT23795.1\|2231854_2233714_-	LTA synthase family protein	NA	NA	NA	NA
QAT23796.1\|2233714_2233837_+	3-phosphoglycerate dehydrogenase	NA	NA	NA	NA
QAT23797.1\|2233831_2234992_-	hydroxyacid dehydrogenase	M1NSB9	Streptococcus_phage	7.3e-61	35.8
QAT23798.1\|2235299_2236724_-	L-arabinose isomerase	NA	NA	NA	NA
QAT23799.1\|2236739_2237438_-	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
QAT23800.1\|2237394_2239056_-	ATPase	NA	NA	NA	NA
QAT23801.1\|2239274_2240675_+	sugar porter family MFS transporter	NA	NA	NA	NA
QAT23802.1\|2240606_2240786_-	hypothetical protein	NA	NA	NA	NA
QAT23803.1\|2240832_2241912_-	GntR family transcriptional regulator	NA	NA	NA	NA
QAT23804.1\|2242029_2243268_-	MFS transporter	NA	NA	NA	NA
QAT23805.1\|2243285_2244287_-	alpha-N-arabinofuranosidase	NA	NA	NA	NA
QAT23806.1\|2244488_2245379_+	ArsR family transcriptional regulator	NA	NA	NA	NA
QAT23807.1\|2245453_2246278_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.4e-77	56.0
QAT23808.1\|2246289_2247762_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	7.0e-109	45.4
QAT23809.1\|2248190_2249219_-	DUF916 and DUF3324 domain-containing protein	NA	NA	NA	NA
QAT23810.1\|2249325_2249949_-	hypothetical protein	NA	NA	NA	NA
QAT23811.1\|2249972_2250545_-	hypothetical protein	NA	NA	NA	NA
QAT23812.1\|2250534_2250831_-	hypothetical protein	NA	NA	NA	NA
QAT23813.1\|2250904_2253700_-	hypothetical protein	NA	NA	NA	NA
QAT23814.1\|2254142_2255684_+	hypothetical protein	NA	NA	NA	NA
QAT24268.1\|2255657_2255903_-	hypothetical protein	NA	NA	NA	NA
QAT23815.1\|2255910_2256267_-	DUF1827 family protein	NA	NA	NA	NA
QAT23816.1\|2256489_2257242_+	MerR family transcriptional regulator	NA	NA	NA	NA
QAT23817.1\|2257357_2258281_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
QAT23818.1\|2258295_2258568_-	hypothetical protein	NA	NA	NA	NA
QAT23819.1\|2258650_2260057_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
QAT23820.1\|2260388_2262014_-	chaperonin GroEL	A0A219YK78	uncultured_virus	4.9e-156	56.8
QAT23821.1\|2262065_2262350_-	co-chaperone GroES	A0A221S4M3	uncultured_virus	2.0e-12	40.2
QAT23822.1\|2262574_2263237_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAT23823.1\|2263313_2264612_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
QAT23824.1\|2264780_2265410_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
QAT23825.1\|2265510_2266320_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	3.1e-34	33.6
QAT23826.1\|2266374_2267244_-	hypothetical protein	NA	NA	NA	NA
QAT23827.1\|2267244_2268561_-	hypothetical protein	NA	NA	NA	NA
QAT23828.1\|2268557_2270393_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	5.2e-37	37.7
QAT23829.1\|2270397_2271102_-	response regulator transcription factor	W8CYM9	Bacillus_phage	5.8e-45	41.6
QAT23830.1\|2271291_2272152_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	6.0e-12	24.5
QAT23831.1\|2272138_2272708_-	DUF1836 domain-containing protein	NA	NA	NA	NA
2273120:2273179	attL	NA	NA	NA	NA
QAT23832.1\|2273363_2274383_-	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	4.1e-60	68.6
QAT23833.1\|2274393_2274591_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	5.9e-24	87.5
QAT23834.1\|2274613_2274907_-	hypothetical protein	NA	NA	NA	NA
QAT23835.1\|2274943_2275081_-	XkdX family protein	NA	NA	NA	NA
QAT23836.1\|2275082_2275529_-	hypothetical protein	NA	NA	NA	NA
QAT23837.1\|2275547_2277827_-	DUF2479 domain-containing protein	A0A060AI60	Enterococcus_phage	3.5e-67	40.7
QAT23838.1\|2277826_2278873_-	hypothetical protein	A0A059T661	Listeria_phage	2.2e-16	31.0
QAT23839.1\|2278872_2279892_-	hypothetical protein	Q9T1A5	Listeria_phage	6.5e-106	55.3
QAT23840.1\|2279900_2280731_-\|tail	phage tail family protein	A8ASK7	Listeria_phage	7.5e-52	40.8
QAT23841.1\|2280741_2285298_-	tape measure protein	A0A060ANI0	Enterococcus_phage	1.9e-237	50.3
QAT23842.1\|2285297_2285489_-	hypothetical protein	NA	NA	NA	NA
QAT23843.1\|2285512_2285824_-	hypothetical protein	A0A0M4R2F4	Enterococcus_phage	2.3e-14	46.7
QAT23844.1\|2285950_2286511_-\|tail	phage tail protein	A0A0S2MY53	Enterococcus_phage	4.0e-41	46.4
QAT23845.1\|2286526_2286898_-	hypothetical protein	A0A060ANH4	Enterococcus_phage	2.1e-22	44.4
QAT23846.1\|2286894_2287290_-	hypothetical protein	A0A0M5M1E5	Enterococcus_phage	5.8e-18	41.7
QAT23847.1\|2287286_2287622_-\|head,tail	head-tail adaptor protein	C0LZZ3	Enterococcus_phage	1.1e-17	42.3
QAT23848.1\|2287599_2287884_-\|head,tail	phage gp6-like head-tail connector protein	A0A0M4S687	Enterococcus_phage	2.3e-16	47.9
QAT23849.1\|2287895_2288105_-	hypothetical protein	A5GYM0	Lactococcus_phage	8.6e-13	61.2
QAT23850.1\|2288149_2289337_-\|capsid	phage major capsid protein	A0A0S2SXJ6	Bacillus_phage	1.2e-79	55.0
QAT24269.1\|2289376_2289922_-\|head,protease	HK97 family phage prohead protease	A0A0M4R4P2	Enterococcus_phage	3.7e-55	59.8
QAT23851.1\|2289869_2291054_-\|portal	phage portal protein	V5US36	Enterococcus_phage	2.5e-77	43.2
QAT23852.1\|2291227_2292952_-\|terminase	terminase large subunit	D7PQ39	Enterococcus_phage	2.7e-168	53.0
QAT23853.1\|2292944_2293424_-\|terminase	phage terminase small subunit P27 family	A0A0M3UL59	Enterococcus_phage	7.7e-41	58.4
QAT23854.1\|2293589_2293964_-	HNH endonuclease	A0A249XUN4	Enterococcus_phage	1.7e-32	55.2
QAT23855.1\|2293965_2294535_-	hypothetical protein	NA	NA	NA	NA
QAT23856.1\|2294599_2294827_-	hypothetical protein	NA	NA	NA	NA
QAT24270.1\|2295381_2295795_-	autolysin	C9E2P5	Enterococcus_phage	1.1e-56	81.0
QAT23857.1\|2295870_2296167_-	hypothetical protein	NA	NA	NA	NA
QAT23858.1\|2296166_2296361_-	hypothetical protein	NA	NA	NA	NA
QAT23859.1\|2296357_2296681_-	hypothetical protein	NA	NA	NA	NA
QAT23860.1\|2296677_2296956_-	hypothetical protein	R4JMM4	Bacillus_phage	1.8e-18	54.4
QAT24271.1\|2296952_2297528_-	DUF1642 domain-containing protein	A0A059T7S4	Listeria_phage	4.9e-18	43.4
QAT23861.1\|2297584_2298025_-	hypothetical protein	A0A1S5SFT9	Streptococcus_phage	4.6e-08	34.9
QAT23862.1\|2297987_2298455_-	HNH endonuclease	A0A1S5SA27	Streptococcus_phage	2.4e-55	67.8
QAT23863.1\|2298451_2298769_-	DUF1140 family protein	A0A2H4JAZ4	uncultured_Caudovirales_phage	7.9e-10	36.4
QAT23864.1\|2298768_2299074_-	hypothetical protein	NA	NA	NA	NA
QAT23865.1\|2299070_2299232_-	antitoxin	NA	NA	NA	NA
QAT23866.1\|2299228_2299546_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	7.6e-29	61.0
QAT23867.1\|2299861_2302198_-	DNA primase	Q9T0Y1	Lactobacillus_phage	8.5e-226	51.0
QAT23868.1\|2302197_2302704_-	DUF669 domain-containing protein	A8ATF2	Listeria_phage	1.1e-34	45.2
QAT23869.1\|2302721_2304245_-	DEAD/DEAH box helicase	Q9T0Y3	Lactobacillus_phage	2.3e-107	49.3
QAT23870.1\|2304216_2304957_-	DNA-binding protein	A0A1X9I651	Streptococcus_phage	9.0e-65	54.4
QAT23871.1\|2304977_2305457_-	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	1.8e-34	49.7
QAT23872.1\|2305389_2305707_-	hypothetical protein	NA	NA	NA	NA
QAT23873.1\|2305918_2306170_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
QAT23874.1\|2306340_2307081_-	phage antirepressor protein	A0A1P8BLA9	Lactococcus_phage	1.4e-60	50.2
QAT23875.1\|2307077_2307341_-	XRE family transcriptional regulator	E8ZDN3	Streptococcus_phage	9.8e-14	53.5
QAT23876.1\|2307497_2308151_+	helix-turn-helix domain-containing protein	E9LUS8	Lactobacillus_phage	1.4e-40	43.7
QAT23877.1\|2308249_2308981_+	SHOCT domain-containing protein	X5JB37	Clostridium_phage	5.3e-17	38.1
QAT23878.1\|2309091_2310303_+\|integrase	site-specific integrase	A0A0B5CTW8	Listeria_phage	7.2e-35	30.3
QAT23879.1\|2310649_2312377_-	ABC transporter permease subunit	NA	NA	NA	NA
2310435:2310495	attR	NA	NA	NA	NA
QAT23880.1\|2312369_2313563_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-29	37.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP035221

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP035220

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection