CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP035283	Caproiciproducens sp. NJN-50 chromosome, complete genome	3 crisprs	csa3,RT,WYL,DEDDh,cas1,cas3	0	0	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP035283_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035283_1

25987-26097

Orphan

Consensus_repeat	Method
TACACATTGAAGCGGAACAAAACCACGTCGCTGTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035283_1

>merge|CP035283|1|25987-26097|CRISPRCasFinder
TACACATTGAAGCGGAACAAAACCACGTCGCTGTCCCGGGCCGTTCGGCCTTTCGCGGCTCCGCCGGTCACGGCTTACACATTGAAGCGGAACAAAACCACGTCGCCGTCC

>CP035283|1|1|25987-26097|CRISPRCasFinder
TACACATTGAAGCGGAACAAAACCACGTCGCTGTCC	CGGGCCGTTCGGCCTTTCGCGGCTCCGCCGGTCACGGCT
TACACATTGAAGCGGAACAAAACCACGTCGCCGTCC

Protein	Signature genes	Signature genes Name	Protein_function
CP035283.1\|QAT48317.1\|37760_38726_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
CP035283.1\|QAT48310.1\|31761_32166_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319905
CP035283.1\|QAT51178.1\|23406_24135_-\|hypothetical-protein	unknown	unknown	unknown
CP035283.1\|QAT48306.1\|25160_25700_-\|rubrerythrin-family-protein	unknown	unknown	gnl\|CDD\|153100
CP035283.1\|QAT48301.1\|21731_22094_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319925
CP035283.1\|QAT48298.1\|17742_19470_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378253
CP035283.1\|QAT48305.1\|24822_25032_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|226181
CP035283.1\|QAT48314.1\|34336_34909_+\|proton-coupled-thiamine-transporter-YuaJ	unknown	unknown	gnl\|CDD\|370542
CP035283.1\|QAT48299.1\|19472_20918_+\|DUF4340-domain-containing-protein	unknown	unknown	gnl\|CDD\|379518
CP035283.1\|QAT48312.1\|33082_33475_+\|thioesterase	unknown	unknown	gnl\|CDD\|227783
CP035283.1\|QAT48309.1\|29425_31621_-\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
CP035283.1\|QAT48315.1\|35309_35837_+\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|378961
CP035283.1\|QAT48313.1\|33471_34131_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798
CP035283.1\|QAT48300.1\|21025_21706_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372652
CP035283.1\|QAT48311.1\|32153_32936_-\|DUF1624-domain-containing-protein	unknown	unknown	gnl\|CDD\|377915
CP035283.1\|QAT48303.1\|22721_23417_+\|hypothetical-protein	unknown	unknown	unknown
CP035283.1\|QAT48308.1\|27174_27807_-\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
CP035283.1\|QAT48316.1\|35842_36442_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
CP035283.1\|QAT48304.1\|24353_24812_+\|DUF2975-domain-containing-protein	unknown	unknown	unknown
CP035283.1\|QAT48302.1\|22246_22729_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP035283.1\|QAT48317.1\|37760_38726_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.04305e-81
CP035283.1\|QAT48310.1\|31761_32166_+\|glyoxalase	gnl\|CDD\|319905	cd07241, VOC_BsYyaH, vicinal oxygen chelate (VOC) family protein similar to Bacillus subtilis YyaH. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.61955e-50
CP035283.1\|QAT48308.1\|27174_27807_-\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	2.51863e-48
CP035283.1\|QAT48301.1\|21731_22094_+\|VOC-family-protein	gnl\|CDD\|319925	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.22957e-08
CP035283.1\|QAT48298.1\|17742_19470_+\|hypothetical-protein	gnl\|CDD\|378253	pfam09822, ABC_transp_aux, ABC-type uncharacterized transport system. This domain is found in various eukaryotic and prokaryotic intra-flagellar transport proteins involved in gliding motility, as well as in several hypothetical proteins.	3.76351e-22
CP035283.1\|QAT48305.1\|24822_25032_+\|transcriptional-regulator	gnl\|CDD\|226181	COG3655, COG3655, Predicted transcriptional regulator [Transcription].	2.33421e-27
CP035283.1\|QAT48314.1\|34336_34909_+\|proton-coupled-thiamine-transporter-YuaJ	gnl\|CDD\|370542	pfam09515, Thia_YuaJ, Thiamine transporter protein (Thia_YuaJ). Members of this protein family have been assigned as thiamine transporters by a phylogenetic analysis of families of genes regulated by the THI element, a broadly conserved RNA secondary structure element through which thiamine pyrophosphate (TPP) levels can regulate transcription of many genes related to thiamine transport, salvage, and de novo biosynthesis. Species with this protein always lack the ThiBPQ ABC transporter. In some species (e.g. Streptococcus mutans and Streptococcus pyogenes), yuaJ is the only THI-regulated gene. Evidence from Bacillus cereus indicates thiamine uptake is coupled to proton translocation.	4.09763e-39
CP035283.1\|QAT48300.1\|21025_21706_+\|hypothetical-protein	gnl\|CDD\|372652	pfam13624, SurA_N_3, SurA N-terminal domain. This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.	1.69799e-06
CP035283.1\|QAT48312.1\|33082_33475_+\|thioesterase	gnl\|CDD\|227783	COG5496, COG5496, Predicted thioesterase [General function prediction only].	5.4781e-30
CP035283.1\|QAT48309.1\|29425_31621_-\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
CP035283.1\|QAT48315.1\|35309_35837_+\|ECF-transporter-S-component	gnl\|CDD\|378961	pfam12822, ECF_trnsprt, ECF transporter, substrate-specific component. Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.	2.9131e-05
CP035283.1\|QAT48313.1\|33471_34131_+\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.69413e-75
CP035283.1\|QAT48299.1\|19472_20918_+\|DUF4340-domain-containing-protein	gnl\|CDD\|379518	pfam14238, DUF4340, Domain of unknown function (DUF4340). This domain is found in bacteria, and is typically between 183 and 196 amino acids in length.	4.34382e-16
CP035283.1\|QAT48311.1\|32153_32936_-\|DUF1624-domain-containing-protein	gnl\|CDD\|377915	pfam07786, DUF1624, Protein of unknown function (DUF1624). These sequences are found in hypothetical proteins of unknown function expressed by bacterial and archaeal species. The region in question is approximately 230 residues long.	2.29927e-36
CP035283.1\|QAT48316.1\|35842_36442_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.80822e-16
CP035283.1\|QAT48306.1\|25160_25700_-\|rubrerythrin-family-protein	gnl\|CDD\|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	2.3415e-57

>CP035283.1|QAT48306.1|25160_25700_-|rubrerythrin-family-protein
MELKGSKTEKNLLAAFAGESQARNKYTFYASQAKKEGYEQIAGIFEETANNEKEHAKLWFKCLNGGGIKPTADNLLDAAAGEHYEWTDMYKNFADTAEEEGFKEIAATMRLVAGIEKTHEERYAKLTANLKDNLVFQCAEETVWVCRNCGYVYVGKTAPKVCPACKHPQAYFERRAVNY
>CP035283.1|QAT48305.1|24822_25032_+|transcriptional-regulator
MAIILRLDRVMADRKISLKELSEKVGIANVNLSKMKTGKISAIRFSTLNAICRALDCQPGEILEYRRDD
>CP035283.1|QAT48304.1|24353_24812_+|DUF2975-domain-containing-protein
MAAVRIVQAIIALSVALSLLTAVLPGTFFAPRMDRTGGFWIITFSNVFTNVVFLAVLFLMGRFLQTLKDKSPFVRENVKKLKLASGLLIAVEPVQFIFQSVSNAVRPAANGQKEVLITSFGGIIFVLGLVVFCLSLVFEYGIELQKQSDETL
>CP035283.1|QAT51178.1|23406_24135_-|hypothetical-protein
MDIGNCKYVASCVFTREKPELSEKIQEYLERRFHMEIIRCCVPNYKLEEFTAQMPEWLRPRWRATPDFQNFSEGDTMVYVCHNCAAIFQETMPQVKRLSLWELILQDEEFPFPDYSHEKMTVQDCWRSRDNLAEQKAVRALLRKMNVEIVEQEENYEKTQFCGVSLYAPSPARNLKLAPKRFVMDAKGKFIPLPEEEQNRLMQEHCQKITTDRIVAYCHYCVKGLRLGGKRTDHLAGLLFNP
>CP035283.1|QAT48303.1|22721_23417_+|hypothetical-protein
MNESFLARAGLSAEESERFRAGLLWALADQLSRYTAGQSSSVPEEAAENVLESMLYCVSVELSFRPDPAAALRAVLPDELFRCGCERVKGMVSDLKVLYREVLKTRIPTELIVYNATLDGAVPGFFKSYDPEYAAHENGALTGFPDYPLLCGDKSRGGVLYMSHYLEELLRENRFCARYKKNYIRAVLTLHGQKHRLDYREMIVNIPELLLEREHAPKPYRLPEEQESVTD
>CP035283.1|QAT48302.1|22246_22729_+|hypothetical-protein
MEFQLSSFLRPSALDDARTAENLLTLNEETQEFGLELSREDALALAETRRIALQASGRVEFGTPVLEKIIRAFSRSRYLYQYDYAPALHELLEAFFLLKNETEDRFSDDNLVDFLFDCFESRYRGSLEMFQGPELEQLRRLLLFGAEEEKDDWDGEDKDE
>CP035283.1|QAT48301.1|21731_22094_+|VOC-family-protein
MSLSFHLTSLYVCVKDMERAIRFYEILLGQKVTKKDPVYSVFDINGFRYGLFANEKRNEQHSWGNSCLPSLEVTDMDLALKRLEELHCPIVFAPTVIGKNQVLEFLDSEGNQVELTCPFN
>CP035283.1|QAT48300.1|21025_21706_+|hypothetical-protein
MGKEMRFSLKKSRLLPIVFGSAVMIAACCAVAAANGSFPWNAMKWQTDSGEAVEAYVNGEPILKKTLDKAIGDTRKMEEITARLFPSKQKSSKSESEVLDDLIKAKVLEQEAEKEGITVTDRDALDSLRATDRQIQDLMENGSEEEKKNAKESWDTLTSVASALHESMDQYEKNAVPTERNILIQNRLYQKYVAGHSSMTETKQEMWDGHVAELMKKADVKHRDSP
>CP035283.1|QAT48299.1|19472_20918_+|DUF4340-domain-containing-protein
MRSNIRNLIIVAVCIVVLGGALLTLKLTGNDKAASSSASSTASIELVSKKSEDVVSMNVVNEKGSYTLIPVKTPAASGASSASSGDSGPAYTVKELGGCPINTSATESVVKNGFSLVASKNLGTVSNLEEFGLKDPQATVKVQFRDGSSYDYKIGKTSATDSSAYYMCGLNSENVYIVSVDQGLLEDAGYFVSKDILAITNSSGENNFTKIALSGANYPQPVAFSVYKTDLRISSPSAYTADSTKLSSLKSALASLTADSVEAVNPDAAALKKYGFDSPTAVAQFSVNGANYTITAGAKDGDGYYVMLGGINVVYKAASSGIEAWALQSLYDLRSKTILAPDVETVKSLTVTVGSSKNVLNLTRAKDEKQSTEDTTYYTYKVTGNAGKSLDYDTNYKNFFTKLTGVSILQEASEKPAGSPVLTVQYQYFDGSSADTVEFYQSGNRRYTAVLNGQVFGIVAQDDIDAVTEDIAALENGKAVG
>CP035283.1|QAT48298.1|17742_19470_+|hypothetical-protein
MNQEKDPRTGALLPEEETPEGNTKAEGEQAGTENREETAAPQGEEQAAGQKPEAEEKADGPAEESKKEKKKAGKPRKGHSEFMKSSKFRHGSISTAFTAGFLVVVVLVNILVGILGQRFPSVNLDLTKTGSNSLSAEGLKVVDKVDLPTNITICATQQQVEGDQIYSDQGIQYSQVGSLLSKIAERNSKITVQYVDLDKNPTFAAEYQSDSIAAGDVIVKTDKRYRILAYTDLFNIQYSSDYTSSQVYSNVEGALVSALNAVISDKLPTVAFDTGHSEKQDMSAFKKLLDNNSFETKDFSLLTDKIPDNTQMIVLGEPAKDYTDDEIKKLSDFLGSKTLAGDRSLMVTFAPSQAEMPKLATFLEEWGIQVPASVIVESDQSKFISSNPIYILSDIQSSLQLKPSSDGSSPDYGYFITPQSSPVKLLFETKGGKTTYPLAKSSDSCYLVDNSTKSTDNLPKQSSNTAALSQETVKNGDKDYNASVIAIGSSALFTDGIINSSAFGNGTYMVDLAKYATGTSDSSSEVQITAKPLNATDITATAQVSTFLGLGVFMFLIPLIIVVLGIWVYHKRRHL
>CP035283.1|QAT48308.1|27174_27807_-|O-methyltransferase
MDEKAGEFIESLYRRKETLTKDEFVRLTEWKDFIPVVDDDVARFLRLVLAMKKPKRILEIGTSIGYSATNMALAAREYGGRIITLENDPKAAAQARENFRRAGVDSVAAVREGDALYLLPALGSGSFDLVFQDADKRLYSRLLPECIRVLAPGGIFLADDALFPAMDLDEKWQDLVAPMEKFDRQVAASPELVSTLLPIGDGLICAVKKD
>CP035283.1|QAT48309.1|29425_31621_-|RNA-binding-transcriptional-accessory-protein
MDPITELTRRFNLQEWQVKNVVELIDAGNTIPFIARYRKEAHGSLDDQVLREIAERLDYLRSLEKRREEVKTLIEETGLLTPEVTAELQKAETLAEIEDIYRPFRPKRKTRASVAKEKGLEPLAEQIGKQGPGEPVLLAQSYVNPEKGVETPEDALAGALDILAERVSDNAEIRRRLRVVASAHGILVSKAAKPEEDSVYAPYYDFHEPVNKIAGHRVLAADRGEKEGFLKLSVELERARGLSIVFSECVRGDTPCARAVRAACEDAYDRLIFPSIEREIRNSLTEAADESAVRVFAVNLRQLFLQPPVRGKVAMGLDPGYRTGCKVAVVDATGRVLDTGVIYPTHSQAKVEEAKETVRRMILKHHVEVIAIGNGTASHETEEFAAGVIRELDAGVSYMVVSEAGASVYSASKLAAQEFPEFDVTLRSAVSIARRLQDPLAELVKIDPKAVGVGQYQHDMPKKMLDSALSGVVEDCVNSVGADLNTASPSLLEHIAGITPAVSKNIVGYREENGAFRSRKELLKVPKLGPKAFEQCAGFLRVPESEDLLDHTAVHPESYAAAKALLKLCDYSAAEIRRGSFPGLTEKVERIGREKAAAETGVGVPTLLDIVAELQRPGRDPRDELPKPLLRTDVMKLEDLKPGMELTGTVRNVIDFGAFIDIGVHQDGLVHVSQICDRFIKHPSEVLKVGDIVKVWVLSVDVKKQRISLTMRGGESPRTTARRSANGESVG
>CP035283.1|QAT48310.1|31761_32166_+|glyoxalase
MTITHAAIYTLNLERLKDFYCRWFGGEAGPAYENPEKGFSSRFVRFGQGAALELMHRTHLKESVRGEFTAGYAHLAFSAESEEAVENLTKKMRAGGVPVVSGPRHTGDGCFESCVLDPDGNRVEITAEPKVQEK
>CP035283.1|QAT48311.1|32153_32936_-|DUF1624-domain-containing-protein
MPEKSAAPNGRGRIYLMDELRGFAVFCMVFYHGFYTFGYLFGNDVGIYFFRFFMPAEPFFAGMFLFISGIASNLTHSNLARGTKLLAVALGVTLVTWIFLPEDVITFGVLHFLAVCMILFGLLKPYADRFRFSWVPVLVCFALYFLTRGVPYGTLGCGRGLGIPLPEGLYASAWLAPLGFPGPGFESSDYFPMLPWIFVFAAGTFVGKLAGAGRFPEIAYRSQVPVLSWFGRHALVLYLFHQPVIYGLCLLLKQAASYFS
>CP035283.1|QAT48312.1|33082_33475_+|thioesterase
MPDTRLTKEFTVSQEMLASRMGSGLLPVLATPIVAAFFENTAMEIAAGYLSDGETTVGSKITVEHLAPTAPGCKVTVTAELEEHEKRTFRFRLEARDNAGVVATGTHVRVSVAGERFMKKAEERKNTVAQ
>CP035283.1|QAT48313.1|33471_34131_+|HAD-family-hydrolase
MSLRCDLILFDLDGTLTDSGPGITNGLREAFRHVGWPVPGPQVLRRFIGPPLLNMLKELFPRMTEKTTAELIGDYRRYYAERGAFENEVYPGIFDLLDELRLGGAKLAVVTSKPATPTKRILDYFGLSPHFDYVSAESDSDRGSGKEFLIRPALEHFGVPASRAVMIGDTKYDAAGARRAGTNFVGVLYGFGTREEMEREGGEHFSRTVEDLRGFLIDK
>CP035283.1|QAT48314.1|34336_34909_+|proton-coupled-thiamine-transporter-YuaJ
MTNEKSNSGMNAANLRLVESAIMLALATVLSLIKVYQMPLGGSVTLCSMLPVLLIGYKYGFKWGVLTGFTYGVIQLLLDVAAVMSWGLTPVAVAASFAFDYLLAFTCLGLAGIYGKSFPKFVAGMFTAVFLRFLSHVISGVTAYASWLPDEWHGHLWLYSIAYNGSYVLPDFAVCLVVGALLYKPLRRFL
>CP035283.1|QAT48315.1|35309_35837_+|ECF-transporter-S-component
MKKSMTVNLTGAALCIALGLILPVLFHMVGAGSVFLPMHIPVLLCGLLFGWQYGAVCGLIVPLLSSLLTGMPPIFPTAAAMMLELCAYGLLTGLFYRKMRWNVYPALICAMLGGRVVSGAANAVFLGMADKPYGFAAFLSASFVQAVPGIIIQIVFIPVIVLALEKASVFRRERA
>CP035283.1|QAT48316.1|35842_36442_+|class-I-SAM-dependent-methyltransferase
MMETASQTGEIREFFDRCAETWDCLDRGRPEKIAAIVTLSGVKEGSRVADIACGTGVLFPEILSRNPAFLLGTDLSEKMIGRARAKFSDGRLRTVASDCFELRESGFDTILIYNAYPHFPDKKRLAEKMASMLRKGGRLMIAHGTGRAAINGRHNGKMTGRISWELRSAEEEAAEFSGLFQIDMTADTEEIYFFSGFRK
>CP035283.1|QAT48317.1|37760_38726_-|IS30-family-transposase
MDYHHLTPKERALIAQLWNNGISMRQLARRLQRDPGTISREIKRNRSGQKYLSVPARARYLERRMECRRKRLYQNPRLTAYISEKLELSWSPEQIAGRIRLDYPDDRDMKISHSSIYRSLRADLLPRSVQLTMKLRHYGRQHGETRGYKAGAREIRERSKEVLRRKRLGDWEADTIVFGQAKRVYLLNVTDRKSRYCCLAVLRNIRREEVMRGFEFFFEGGKVPLRTVTSDRGIEFNCHREFESRFEALYYYTRPASPWQKPTVENTNGLIRQFFPRGTRFTELTPEAVAFVMERLNDRPRKCLNWKTPAEVISSYLLHFT

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Crispr_ID: CP035283_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035283_2

104092-104202

Orphan

Consensus_repeat	Method
TTAAGAGCCACCGGGCCTTAGGCCCGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035283_2

>merge|CP035283|2|104092-104202|CRISPRCasFinder
TTAAGAGCCACCGGGCCTTAGGCCCGCAGAGACCCGGCCCGCGCGGCCTGAGCGCAGAAGAGAAAATCAGAAGAAATAAAGGCTTAAGAGCCACCGGGCCTCAGGCCCGCA

>CP035283|2|2|104092-104202|CRISPRCasFinder
TTAAGAGCCACCGGGCCTTAGGCCCGCA	GAGACCCGGCCCGCGCGGCCTGAGCGCAGAAGAGAAAATCAGAAGAAATAAAGGC
TTAAGAGCCACCGGGCCTCAGGCCCGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP035283.1\|QAT48383.1\|113398_114064_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
CP035283.1\|QAT48382.1\|111958_113332_-\|Trk-system-potassium-transporter-TrkA	unknown	unknown	gnl\|CDD\|236541
CP035283.1\|QAT48367.1\|90857_92009_+\|2-oxoacid:acceptor-oxidoreductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181526
CP035283.1\|QAT48377.1\|106213_106633_-\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
CP035283.1\|QAT48368.1\|91987_92797_+\|2-oxoacid:ferredoxin-oxidoreductase-subunit-beta	unknown	unknown	gnl\|CDD\|235604
CP035283.1\|QAT48376.1\|104792_106169_-\|glycine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235240
CP035283.1\|QAT48380.1\|109907_110468_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|238032
CP035283.1\|QAT51179.1\|93424_94381_+\|CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
CP035283.1\|QAT48384.1\|114083_114707_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
CP035283.1\|QAT48373.1\|97856_98651_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
CP035283.1\|QAT48381.1\|110501_111962_-\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223246
CP035283.1\|QAT48370.1\|94398_95163_+\|CoA-transferase-subunit-beta	unknown	unknown	gnl\|CDD\|224968
CP035283.1\|QAT48369.1\|92796_93348_+\|2-oxoacid:acceptor-oxidoreductase	unknown	unknown	gnl\|CDD\|181462
CP035283.1\|QAT48371.1\|95185_96586_+\|sodium:solute-symporter-family-protein	unknown	unknown	gnl\|CDD\|271357
CP035283.1\|QAT48378.1\|106874_107417_+\|hypothetical-protein	unknown	unknown	unknown
CP035283.1\|QAT48385.1\|115252_116302_+\|membrane-dipeptidase	unknown	unknown	gnl\|CDD\|238626
CP035283.1\|QAT48375.1\|100026_103083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319848
CP035283.1\|QAT48374.1\|99237_100008_+\|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	unknown	unknown	gnl\|CDD\|129290
CP035283.1\|QAT48379.1\|107466_108183_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|377026
CP035283.1\|QAT48372.1\|96808_97747_-\|class-II-fructose-1,6-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|180829

Protein	Function_ID	Function_description	E-value
CP035283.1\|QAT48383.1\|113398_114064_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	6.67503e-48
CP035283.1\|QAT48382.1\|111958_113332_-\|Trk-system-potassium-transporter-TrkA	gnl\|CDD\|236541	PRK09496, trkA, Trk system potassium transporter TrkA.	2.08435e-178
CP035283.1\|QAT48367.1\|90857_92009_+\|2-oxoacid:acceptor-oxidoreductase-subunit-alpha	gnl\|CDD\|181526	PRK08659, PRK08659, 2-oxoacid:acceptor oxidoreductase subunit alpha.	0
CP035283.1\|QAT48377.1\|106213_106633_-\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	2.32045e-19
CP035283.1\|QAT48368.1\|91987_92797_+\|2-oxoacid:ferredoxin-oxidoreductase-subunit-beta	gnl\|CDD\|235604	PRK05778, PRK05778, 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Validated.	3.3704e-117
CP035283.1\|QAT48376.1\|104792_106169_-\|glycine--tRNA-ligase	gnl\|CDD\|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
CP035283.1\|QAT48380.1\|109907_110468_-\|HD-domain-containing-protein	gnl\|CDD\|238032	cd00077, HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.	5.6763e-08
CP035283.1\|QAT51179.1\|93424_94381_+\|CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	3.39094e-46
CP035283.1\|QAT48384.1\|114083_114707_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	2.5401e-31
CP035283.1\|QAT48373.1\|97856_98651_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	3.38328e-50
CP035283.1\|QAT48381.1\|110501_111962_-\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	4.77383e-113
CP035283.1\|QAT48370.1\|94398_95163_+\|CoA-transferase-subunit-beta	gnl\|CDD\|224968	COG2057, AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid metabolism].	1.85891e-40
CP035283.1\|QAT48369.1\|92796_93348_+\|2-oxoacid:acceptor-oxidoreductase	gnl\|CDD\|181462	PRK08537, PRK08537, 2-oxoacid:ferredoxin oxidoreductase subunit gamma.	2.20802e-39
CP035283.1\|QAT48371.1\|95185_96586_+\|sodium:solute-symporter-family-protein	gnl\|CDD\|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	3.67264e-63
CP035283.1\|QAT48385.1\|115252_116302_+\|membrane-dipeptidase	gnl\|CDD\|238626	cd01301, rDP_like, renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. Although the biological function of the enzyme is still unknown, it has been suggested to play a role in the renal glutathione metabolism.	9.28696e-85
CP035283.1\|QAT48375.1\|100026_103083_+\|hypothetical-protein	gnl\|CDD\|319848	cd07550, P-type_ATPase_HM, P-type heavy metal-transporting ATPase; uncharacterized subfamily. Uncharacterized subfamily of the heavy metal-transporting ATPases (Type IB ATPases) which transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	8.69774e-18
CP035283.1\|QAT48374.1\|99237_100008_+\|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	gnl\|CDD\|129290	TIGR00186, Uncharacterized_tRNA/rRNA_methyltransferase_MG252, rRNA methylase, putative, group 3. this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification].	3.11068e-81
CP035283.1\|QAT48379.1\|107466_108183_-\|flavodoxin-family-protein	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	1.92654e-22
CP035283.1\|QAT48372.1\|96808_97747_-\|class-II-fructose-1,6-bisphosphate-aldolase	gnl\|CDD\|180829	PRK07084, PRK07084, class II fructose-1,6-bisphosphate aldolase.	1.06826e-177

>CP035283.1|QAT48375.1|100026_103083_+|hypothetical-protein
MNDNGKTPRNDYSVEEILAEARIIKDRETVPPESETAPEKSPAPTAPHGSEEILRGARRALNMEAGSEEDPGETGPQEPEPEKERKKHWFSLFGRRKKSEEFREEDDLYYGLQLRPLEEYRKEYEKTIRPEGSENPESGEEAKEDGPKFSYLFDGSEGDGEPGIGETFDRIHRERHERLEKIMRQAGLDPEEILPQEEPANPPEVPPPAPSGPEIPQPEAPERPAVTPGPRREPEVRPPVTRPVPEPPVPPEVTTEEDQEEGEESQADSAPEKSGPAKAEETPPVPVKEPVKTPPEAKQERRVPPPRTEPSDTPRPQYRAGGAPVHVILPRGLKEILETEAAEYPMPEPPGPIPFPKRESGPIPEPEEESGQTPKKPEPEPELAAGDPERQENRTEPEPPAGENPPEPEEPPAPPRGARHRFRLFGAEEPEESFAEEPPEQEELDDYTDPSDAPSVRHDLLKNVTRLSLRLAVTGITSLILLLVGIVAEHPAVLPPDLHTILDGPSYPFIQLVFLIVAAGFSFPTFWNGIKGLTSFQANGDSAAAVAVLAALVQNVVLLVLGVPGGIHLYSPLAAFALFLNAAGKFSMARRMFENFRYLCTKDRKYAVRLYGDYNTSLRLAKDCVLGEPHIAYQSEAAFLRSFLRISYTPDPADHISQVLAPAGFLLSLALCAAAAFLTSGGAVSAITVLAASCCVCVPFTNMLCVNLPVSRLCGIARRSGSMVAGWSAIDRFSAANAVMLDAQDLFPRGTVILNGIRTFAGQRIDEAIMDAAALMGTVGGPLSDLFDQIIKSRREILPKIGEPVYEDGKGVSGTVSGRQILIGTNELMRAHGIEPPSRDYEKKYIQSGKRLVYLASGGCLVAMFIIDYTSDLRRSQALRRMERNGISLIVRTSDPNITPRFLAECFGLYEQEISVLPEQLGKVYTGLISAEPDRADAMIATKGRAFAMLRLLTGCIRQRANISVAVALQAAAVALGFALVAFLSLTSGLQHLSLTALAIYEAFWTAAILLVPRIRRP
>CP035283.1|QAT48374.1|99237_100008_+|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB
MKNGGEGQGDSGVIAGRNAVAEALRSGRAIDRLCLARGERSGSVVALIAKAKQRGIPVKEIDPKKLDFMCGGAVHQGVAAVAAAKEYSTVDEMFRLAQERGEPPFLIVADGLEDPHNLGAVLRVAECAGAHGVILPARRSVGLTWAVGKSSAGAVEYVPVARVANLASALEDLKRRGVWIYAADLDGEPWCGVDYSGPVAVVIGSEGTGVGRLVKEKSDFVISLPIRGKINSLNASVACGVICYEIARQRLGIKTK
>CP035283.1|QAT48373.1|97856_98651_-|DNA-3-methyladenine-glycosylase-2-family-protein
MKRKGGEKLMNLDTLGQTLDCGQCFRWERLPDGSWQGAAGDRCAHLTAESWESVLADPFWTSYFDMGRDYEAIRERLGALDPILAEAARYAPDLRILNQDPWEALCSFLLSQCNNIKRIKGLVARLCRAYGEPSGPFPAFPRPEALARLSERDLRALGCGYRAEYLLHAARRAAEGKLDFGRLRRLPLSDARRELTELPGIGPKVADCALLYGLHRLEAFPMDVWMKRAMKTLFPGRKAEDFGEYAGIAQQYIFHYSRNHPELF
>CP035283.1|QAT48372.1|96808_97747_-|class-II-fructose-1,6-bisphosphate-aldolase
MSLVNTKEMFQKAYGGGYAIGAFNVNNMEIVQGITEACAELKAPVILQASAGARKYATHTYLVKLVEAAVVEHPELPVALHLDHGPSYEVCKDCIDGGFTSVMFDGSSKHYEENVEETRKVVAYAHKYNVTVEAELGRLAGIEDAVSVADDKAQYTDPDQVQDFVKSTGVDSLAIAIGTSHGAYKFKPGQKPQLRFDILEEVSRRLPGFPIVLHGASSVIPEFVQMINQYGGKMPDAIGIPEDMLRKAATMAVCKINIDSDLRLAMTATVRKYFAEHPDHFDPRQYLGPARDAIKGMVEHKITAVLGCANKI
>CP035283.1|QAT48371.1|95185_96586_+|sodium:solute-symporter-family-protein
MNLLHFAGAAAVLLLITAVGVYSGRKVKSAADFATGGCSAGTGIVAGSLVGTLVGGASTIGTAQLAFTYGFSAWWFTLGGGIGLLLLALFFAKPLYNSKITTLPQIFTREYGRRTATVSTVLISVGTFLSIVSQLLSGVALVTSVSSVNALAAAAVIVLLMLAYVVFGGVWGAGLVGIVKTILLYVTTIVCGAVALKLAGGLDSLRSSLRPEQYFNLFARGVWKDGGAGLSMVFGILTTQSYVQSLVSAKSARVAKSGALLAGVLTPVIGVAGIFVGMYMRIAAPDIVPASAMPAFVLRCLPPLLGGVVLATLLVALVGTGAGLALGLSSMICNDIYKVYMNRNAADNVLLRISRTVIFAILGGAFLFTFGNMGSLILNWSFLSMGLRGAVAFAPLLFALFFPGRVKGTAALAAVIAGPICILAGEFVLPEQIDPLFLGIGVSLCIMLFQMRPRAEQEKVKTEDKG
>CP035283.1|QAT48370.1|94398_95163_+|CoA-transferase-subunit-beta
MNWTPKQMMAVALARQIEDGKTYIIGTGLPLIGGALAKNTSAPNAHLIFETALFEGSPQEVPTSVSDLRINYQASVLWPQYRYFGFQILAARRGKIAAGFLGGAQIDPYGNLNSTCIGDYPHPQTRFTGSGGANGIATYCDTVIVMKHQKRRFVEHVDYITSPGWGDGPGGRAEAGLDSGRGPRAVITDLGVLRFDAVSRRMYLSECFPGVVPEKVQENTGFELDVSRAVEAVPPSEKILEILIHQVDPLRIMI
>CP035283.1|QAT51179.1|93424_94381_+|CoA-transferase-subunit-A
MSKVMSAEEAVASFLRDGDCLAVGGFVTNRRPYALVREVIRQKKRNLYVEGGPSGGDIDMLIGAGCVEIIMVSYIANSGYTQVCRRFRDAVEHGKILFEDYSMDVQTIIYHGAALGLSYIPVKNMLGSDLAEKWGISREERKKHPKLPGEKFVVQEDPFHPGSKLCCVPTPEIDVALIHAQLASPDGTVRIVGAPFQDADIAMAAKHTIVSCEQLVSNEEIRRHPERNTLTGLCVDAVVEAPAGAHPSQCFGCYDYDSQFYLDYDRASRSQEDFDSFIREYVEDCPAHQDYLDKLGAGRLINLRVKPGLGYVPGLKRR
>CP035283.1|QAT48369.1|92796_93348_+|2-oxoacid:acceptor-oxidoreductase
MGKQTEITISGVGGQGMILCGTLIAETAVLQEQKMATLTSDYGVETRGTFSKSDVIISDREIFFPDVTEPDLVVCLAQVAYERYSGKIGEKAILLYDSDSIVPHPEQAARERGIAVSSLARETGNPATANILTMGLIAGFTGAVSSEGAKQSLKEFFGRKGEKVLLLNYKAFDTGYALGRNLK
>CP035283.1|QAT48368.1|91987_92797_+|2-oxoacid:ferredoxin-oxidoreductase-subunit-beta
MLQDYLLKEKMPHFWCSGCGNGIVLQSLLRNVDKQKWSRENTVVVTGIGCWGKADDYVRTNTFHGTHGRALAFATGIKLANPGLNVIALMGDGDGITIGGNHLIHAARRNADVTAIMVNNLNYGMTGGQYSGTTPKHAITKTSPYGHVEKGFDVCGVVRAAGAPFVARGTVFDVVQLNRLVELALLHRGFSFVEVISPCPTHFGRSNRMPSAPAMMQWIKDRTVPAAKAQAMSREDLCGKFVTGVFEDREQEDYSTAYQRVIDGLKGEK
>CP035283.1|QAT48367.1|90857_92009_+|2-oxoacid:acceptor-oxidoreductase-subunit-alpha
MGKLRFMQGNEAMTEGAIAAGARFYAGYPITPSTEVAETSAARLPRAGGLYIQMEDELGSMAALIGAVCAGKKAYTATSGPGLSLMSENLGVAVMGEIPCVVIDVQRSGPSTGMATKPAQGDVMQARWGTHGDHSVIALAPSSVQDCFDLMITAFNYAETYRTPVIFLADEIIGHLKERVMLRDPDEIRVVERTGPACAPEKYLPYDHSNGLAPLASYGGKYVFKVNGSMHDEAGRPCTSPRNADRVIRHLSEKIESHAEELTITREFRMDDAEYVVVAYGGTVRAALSAMEKARARGIRAGVLQLVTVWPAAEKEIGSAMLRAKAVIVPELNLGQYIDVIRLRNSRGIPVVGVNRVDGRPIEPADITAKIEEVSESCCRTIC
>CP035283.1|QAT48376.1|104792_106169_-|glycine--tRNA-ligase
MQATEKTMDQIVALCKNRGFVYSGSEIYGGLSNTWDYGPLGVEFKNNVKAAWRKKFVQESPYNVGLDSAILMNPEVWVASGHVGGFSDPLMDCRDCKARHRADKLIEDFTGESADGWSNQKMMDFIREHHIKCPVCGSENFTDIRQFNLMFKTFQGVTEDAKNEIYLRPETAQGIFVNFANVQRTTRRKIPFGIAQIGKSFRNEITPGNFTFRTREFEQMELEFFCKPDTDLDWFHFWKDFCEKWLMDLGMTEQNIRLRDHEKEELSFYSKATTDIEYLFPFGWGELWGIADRTNYDLSRHQEHSGKSLEFFDPESKEHYIPYVIEPSLGADRVALAFLCDAYDEETLEGGDTRVVMHLHPALAPYKAAVLPLSKKLNGRAQEVYTELAKRFMIDYDDTGSIGKRYRRQDEIGTPFCITFDFDSEKDGCVTVRDRDTMKQERIAIDGLTAYLENKINF
>CP035283.1|QAT48377.1|106213_106633_-|GtrA-family-protein
MKRLLKLWRFLTSPEMILYLVFGVLTTVLNIAVFEFCYSALRWPWQAANALAWVLAVAFAFITNKLWVFRSSSFQADVFWRELLGFVAARLLSLGVDYACMWLFIDILAWNSLAAKAVDNVIVIAINYVLSKLVIFRKK
>CP035283.1|QAT48378.1|106874_107417_+|hypothetical-protein
MEKKNLRKTEGLPFTLGMAAGVVLLLETILSFSLSPIITKVTVDYMSAKMNISAAASSGSSIGGTVGAVVSFLVMPGIFLLLLFLGRNKEKRGSTFAVVWIVIAVLSIVSSVASLMIFQNGELQKQIVEAVNTVMPGGYWIENGLALIGHLLIIASCVVFWKRLHEPPVSEVPGPFGQDA
>CP035283.1|QAT48379.1|107466_108183_-|flavodoxin-family-protein
MKLTVIHGSPRRGNTYRAAQLFLEALKKRGPIEAREFFLPQDLPEFCHGCAACVTRGEEGCPHVSYTKPILDSMLASDALVLTTPVYVMSASGGMKNFLDHYPFLFINHRPKPGFFHKKAFLISTAAGAGTKSAMKPIATSLKYWGINRVYQKGFRIFALSWDEMPPKKQEKYARQLDRSAEKFWRAVRKGDSAPYLFTRFFFFISRMMHKNGADIPLDREYWEARGWLGGKSPFAKQ
>CP035283.1|QAT48380.1|109907_110468_-|HD-domain-containing-protein
MEVPISKIITALLRCDAGDPKRIQHALKVYAFSKAIAEEEGIPRAERDILETAAVLHDIGIHESERKYGSSAGRYQELEGPPVARRILEPLGLPGGFIDRVCFLIGHHHTYNGISGMDYQILVEADFLVNLYEDGSSPETARAAMERIFRTETGKRYLRDQFLSDHPAGDHPVGTVRQSERKKPFA
>CP035283.1|QAT48381.1|110501_111962_-|TrkH-family-potassium-uptake-protein
MNCPLICRYLGYLLWVEAGCMVPPLLIATYYKQGDAPSFLFSIILLTLAGGVMSLCPVRQKRMYGRDGFAIVAIGWLLISIFGALPFVISGAIPSPVDAFFEAVSGFTTTGASILQKVEGLPNGILFWRSFTHWMGGMGVLVLMLALNPNGRIGSNGAISILKAESPGPTPEKLVPRMDHAARILYAIYCVMTVVEILFLRIGRMPLFDSLIHTFGTAGTGGFSNKNLSVAAYHSPYLELVIAVFMLLFGVNFTLYYFLIHKNFRAVLHDEELRFYFGTVAVSTALIALNLCRSMPVPVPEALRQSFFQVSSVITTTGFSSTDFATWPFFSQAILVLLMFLGPCSGSTGGAIKSVRIVVLFKIARREVAKIIHPHSIYRVRLNGRAMEEETISSILSFFFLYIAVFTCALFLILPDGKDLVTSFTAVAATLGNIGPGLGLVGPLGNFSGFSPFSKLVFSFSMILGRLEILPVLVVLAPGCWVKSRG
>CP035283.1|QAT48382.1|111958_113332_-|Trk-system-potassium-transporter-TrkA
MKIIIVGCGKVGYTLAETLSQESHDVTVVDKCAGPLQKAGDDLDVLCIRGNGASVRTLLEAGVRESDLLIAATSSDELNMLCCLTAKKLGVQQTVARIRDPEYAGEISMLRADLDLDMVINPEQAAAEEIARILQFPPAVNVEPFARGKVELVELKVTGQMPLAGLTLKETAAHFPTPILVGAVMREGGVFIPDGSFRILAGDTVYLVGKPSNVFEFCRQIGMPAQKIKNVMILGGGRLSYYLARSLEEARIRVKIIEIRKERCMELSELLSQSLIICGDGSDDALLLSENLEDMGALIAATGRDEDNLIAALLAKQHGVGKVIAKITRLSHPELVQKMGIDSVVNPRQITTDLILRYVRGLTNAQGNPVNTLYRICGGNAEAAEFIADGSTSFLNVPLRDLHMQPGTLIAAIVHGNEIVIPHGDDVLCSGDNVIVLAKDRKFADLNELILTEEVPN
>CP035283.1|QAT48383.1|113398_114064_-|TrkA-family-potassium-uptake-protein
MKVIIVGGGKLGHQIARNLMERKYDVKLIEKDKAKCTRLANSLDAEVIFGDGTELEALEEAGADGADCFIAVTGSDQDNLVASQLAKKEFKIKKVIARNNDPRNLDALRKLGPDIAVSSTEIITNLIEQEVDSAQAHLLATLNRGRASIIALTLPDDTALDGVMLKDLTLPSGSLIISIVRKESLMIPNGLTAFRANDEIVAVCDRNGEIELQRTLGAHAQ
>CP035283.1|QAT48384.1|114083_114707_-|TrkA-family-potassium-uptake-protein
MNVLVIGCGRLGSRLAGILDEQGHDVTVVDSDPDSFHNLKKEFGGITVVGMPMDSKVLRSAGVEGCDAMAVVTPDDNLNITVSQMAREFFGIENVVARISDPLRENIFKRFGLKTVCPTNLAGDAMATALTLPWEPRTVTLGTSTVTFHSKEVDRAHAGMKLSDVPRNSGEQVFGVISADGRMALCRKTEDITLSEGDRVVLTSVID
>CP035283.1|QAT48385.1|115252_116302_+|membrane-dipeptidase
MRQKSNAKKRKETASSIFPVSPPQICIIIEKIKAKTGKGHHMKYFDLHCDTASECCKKGLGLSYNGLHISLEKTERFERWAQVFAVWISDDLRGEAAFRYFQEVTADFKRKLSAEKGKAPVFCVDGPELEKADSAGKNMALLSIEGGAALGGELSHLNEAWETGVRLMTLTWNGPNELGDGCMTPGADGLARFGKEVVKQMGELGMVVDVSHLSEKGFWDVARLAKGPFVATHSDSKAVEDHPRNLTDDQFREIAQRGGLVGLNLYAPFVGGEGSIDGLLRHAEHFLELGGEGTVAVGADFDGCKLRAEIQGVGDMGLLYDAMRARFGEEIADGIFFRNAYRFFTAAYR

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Crispr_ID: CP035283_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035283_3

383408-383513

Orphan

Consensus_repeat	Method
ACATGTATACTTATCGACATGTATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035283_3

>merge|CP035283|3|383408-383513|CRISPRCasFinder
ACATGTATACTTATCGACATGTATGGCTAACGAAGGTAACACCTTCAAATCGAAATGGGATAATTAGCAGATAATATGTATACAAGTATACTTATCGACATGTATG

>CP035283|3|3|383408-383513|CRISPRCasFinder
ACATGTATACTTATCGACATGTATG	GCTAACGAAGGTAACACCTTCAAATCGAAATGGGATAATTAGCAGATAATATGTAT
ACAAGTATACTTATCGACATGTATG

Protein	Signature genes	Signature genes Name	Protein_function
CP035283.1\|QAT48637.1\|372747_373302_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|180928
CP035283.1\|QAT48640.1\|375857_376637_+\|creatininase-family-protein	unknown	unknown	gnl\|CDD\|376872
CP035283.1\|QAT48646.1\|383581_384367_+\|2-hydroxyglutaryl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|224835
CP035283.1\|QAT48643.1\|377892_379158_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238536
CP035283.1\|QAT48647.1\|384382_385633_+\|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|377594
CP035283.1\|QAT48654.1\|392985_394176_+\|electron-transfer-flavoprotein-subunit-alpha	unknown	unknown	gnl\|CDD\|224936
CP035283.1\|QAT48651.1\|389351_390971_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236236
CP035283.1\|QAT48641.1\|376648_377215_+\|aminotriazole-resistance-protein	unknown	unknown	unknown
CP035283.1\|QAT48652.1\|391013_392162_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173847
CP035283.1\|QAT48642.1\|377418_377868_-\|hypothetical-protein	unknown	unknown	unknown
CP035283.1\|QAT48639.1\|375022_375838_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP035283.1\|QAT48649.1\|386807_387974_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226458
CP035283.1\|QAT48645.1\|382400_383099_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
CP035283.1\|QAT48650.1\|388012_389254_+\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110
CP035283.1\|QAT48636.1\|371358_372387_+\|class-B-sortase	unknown	unknown	gnl\|CDD\|320675
CP035283.1\|QAT48653.1\|392179_392965_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
CP035283.1\|QAT48655.1\|394271_395414_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173847
CP035283.1\|QAT48648.1\|385619_386732_+\|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|377594
CP035283.1\|QAT48638.1\|373337_375026_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
CP035283.1\|QAT48644.1\|379989_381096_+\|DUF362-domain-containing-protein	unknown	unknown	gnl\|CDD\|225358

Protein	Function_ID	Function_description	E-value
CP035283.1\|QAT48637.1\|372747_373302_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|180928	PRK07322, PRK07322, adenine phosphoribosyltransferase; Provisional.	8.96129e-80
CP035283.1\|QAT48647.1\|384382_385633_+\|2-hydroxyacyl-CoA-dehydratase	gnl\|CDD\|377594	pfam06050, HGD-D, 2-hydroxyglutaryl-CoA dehydratase, D-component. Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is catalyzed by 2-hydroxyglutaryl-CoA dehydratase, an enzyme with two components (A and D) that reversibly associate during reaction cycles. This component contains one non-reducible [4Fe-4S]2+ cluster and a reduced riboflavin 5'-monophosphate.	5.32318e-72
CP035283.1\|QAT48646.1\|383581_384367_+\|2-hydroxyglutaryl-CoA-dehydratase	gnl\|CDD\|224835	COG1924, COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism].	5.47353e-90
CP035283.1\|QAT48643.1\|377892_379158_-\|hypothetical-protein	gnl\|CDD\|238536	cd01116, P_permease, Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.	3.14737e-137
CP035283.1\|QAT48640.1\|375857_376637_+\|creatininase-family-protein	gnl\|CDD\|376872	pfam02633, Creatininase, Creatinine amidohydrolase. Creatinine amidohydrolase (EC:3.5.2.10), or creatininase, catalyzes the hydrolysis of creatinine to creatine.	1.00468e-83
CP035283.1\|QAT48654.1\|392985_394176_+\|electron-transfer-flavoprotein-subunit-alpha	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	2.89136e-127
CP035283.1\|QAT48651.1\|389351_390971_+\|AMP-binding-protein	gnl\|CDD\|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	6.85317e-133
CP035283.1\|QAT48655.1\|394271_395414_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	2.55334e-178
CP035283.1\|QAT48652.1\|391013_392162_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	4.21898e-167
CP035283.1\|QAT48639.1\|375022_375838_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.23083e-21
CP035283.1\|QAT48649.1\|386807_387974_+\|hypothetical-protein	gnl\|CDD\|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	1.55011e-18
CP035283.1\|QAT48645.1\|382400_383099_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	7.38204e-37
CP035283.1\|QAT48650.1\|388012_389254_+\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.82791e-89
CP035283.1\|QAT48636.1\|371358_372387_+\|class-B-sortase	gnl\|CDD\|320675	cd05826, Sortase_B, Sortase domain found in class B sortases. Class B sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They can have radically distinct functions. Some members of this group attach haemoproteins to the peptidoglycan of the cell wall, while others assemble pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. In transpeptidation reaction, the surface protein substrate is cleaved at a conserved cell wall-sorting signal (Class B sortases normally recognize the consensus NP[Q/K][T/S][N/G/S][D/A] motif), and covalently linked to peptidoglycan for display on the bacterial surface. The prototypical sortase B protein from Staphylococcus aureus (named Sa-SrtB) cleaves surface protein precursors between threonine and asparagine at a conserved NPQTN motif with subsequent covalent linkage to pentaglycine cross-bridges. It is required for anchoring the heme-iron binding surface protein IsdC to the cell wall envelope. SrtB contains an N-terminal hydrophobic region that functions as a signal peptide/transmembrane domain. At the C terminus, it contains an essential cysteine residue within the catalytic TLXTC signature sequence, where X is usually a serine. Genes encoding SrtB and its targets are generally clustered in the same locus. The prototypical class B sortase involved in pilus biogenesis is pilus-specific sortase C2 from Streptococcus pyogenes (named Sp-SrtC2) that anchors a surface protein containing a QVPTGV motif to the cell wall, as well as polymerizes the major pilin subunit Tee3/FctA and attaches the minor tip pilin Cpa. The linkage of Cpa to Tee3 by SrtC2 requires the VPPTG motif in the cell wall-sorting signal of Cpa. The family also includes SrtB enzymes from Bacillus anthracis (named Ba-SrtB) and Clostridium difficile (named Cd-SrtB). Ba-SrtB is thought to recognize the NPKTG motif, and attaches surface proteins to meso-diaminopimelic acid (mDAP) cross-bridges. Cd-SrtB does not play an essential role in pathogenesis. It cleaves short [SP]PXTG motif-containing peptides between the threonine and glycine residues and then covalently anchors the threonine residue to a nucleophile such as glycine or mDAP, but not to the peptidoglycan of C. difficile, suggesting a novel association of sortase activity with cyclic diGMP (c-diGMP)-mediated regulation to control levels of cell wall anchoring and secretion of putative adhesion molecules.	5.00018e-63
CP035283.1\|QAT48653.1\|392179_392965_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	2.14018e-97
CP035283.1\|QAT48648.1\|385619_386732_+\|2-hydroxyacyl-CoA-dehydratase	gnl\|CDD\|377594	pfam06050, HGD-D, 2-hydroxyglutaryl-CoA dehydratase, D-component. Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is catalyzed by 2-hydroxyglutaryl-CoA dehydratase, an enzyme with two components (A and D) that reversibly associate during reaction cycles. This component contains one non-reducible [4Fe-4S]2+ cluster and a reduced riboflavin 5'-monophosphate.	4.78809e-88
CP035283.1\|QAT48638.1\|373337_375026_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	2.5535e-69
CP035283.1\|QAT48644.1\|379989_381096_+\|DUF362-domain-containing-protein	gnl\|CDD\|225358	COG2768, COG2768, Uncharacterized Fe-S center protein [General function prediction only].	5.92776e-117

>CP035283.1|QAT48645.1|382400_383099_-|GntR-family-transcriptional-regulator
MNENIKPRNVQPYTADEVYKKIRRSIIKLQLEPGQMISENQMSQKYNVSRSVIRSAFVRLQQIRFIEIYPQRGTYVSLIDLNHISDLLMLRTAVEKEVIYEMFTSLKKKDRAALVNALESNLAEQEKCRNEPDYNGKFPWIDSDFHKTMIDSVGRYSLVEMLADDMLHIARWRNFDVAFDHRIPALIDQHRAIVEAIKAENMLLAQKKMADHLETISNIADRAKAKFPSYFK
>CP035283.1|QAT48644.1|379989_381096_+|DUF362-domain-containing-protein
MGTSKVYFADMHATLNENLLQKLKRLMITAGVGQIDFNRKYAAIKIHFGEPGNLSFLRPNYAKVVADVVRDLGGSPFLTDCNTLYVGGRKNALDHLDSAYGNGFSHDSTGCHILIADGLKGTDEVLVPVEGGEYVKEAKIGHAIMDADIIISLTHFKGHESTGIGGTLKNIGMGCGSRAGKMEMHSSGKPHVDQEACVGCGSCRKNCAHGAISIENRKASVNHDLCVGCGRCIGVCPMDAVLPASDESNDILDKKIAEYSYAVLHDRPQFHVSLVVDVSPYCDCHAENDIPIVPDVGMFASFDPVALDLACARAVNRQPALPGSLLEKSEKVHQDHFADVHPTTDWNVLIDHAVKLGLGNRDYELVKI
>CP035283.1|QAT48643.1|377892_379158_-|hypothetical-protein
MELIASLTIFVIVMALVMSEKVNRTIAALAGASLLLLLRILTFDEALSYIDFNTLGVLVGMMIIVGIVKDTGVFEYLAIFAAKRVKGDPWKIILSLSVITAVISSFLDNVTTVLLIVPMTFVITDTLELDPIPFLIPEVIASNLGGTATLIGDPPNIMIGSASGLGFMDFLANLGPIVVIIFAVTFFLFYFLFRKQLQVSEEKKLEILSFDEKKSIKDVSLLKKSLAVLVLVILGFFFHEQLNYPSALVALSGAALLLLLSRESVDEVFLNIEWPTLFFFGGLFILVGSLEKVGLINSLATVIVQLTKNNLLLTGIIIIWFSALASSVLDNIPLVATLIPLIKAMGAQGMNISPLWWAISLGACLGGNGTLIGASANVVVAGLAEKHGYKLTFARFTKYGMPLMIVSIILSTLYLILFYLL
>CP035283.1|QAT48642.1|377418_377868_-|hypothetical-protein
MNNLSADQEEIDIKLTQMGANVTSLHGIISFIRFSFDQTELLYVYNINAKNKYFLQMVKPYPAASGVFSKPQEIVQYIKNDIKQFKNASNSNVFGEFVAVNQSLYDSAQKIKDVFMTHNIPKDRMLEVKEKIKEISDLLNEIQSTSSPL
>CP035283.1|QAT48641.1|376648_377215_+|aminotriazole-resistance-protein
MATKRKFSFVNIIFFAIFGVFTGVLWAYGSPIPLIPGAVHFRTFAFVIVTIGFLFGPVTGFFSGYIGTLVWSLLGGYFIAPHTLLADGITVGLSAALPALIMLKNKTLDEYMENKKGFIGKSMFWSLLFGCLMILTTSFSLSFFSGLGYWYCVVWIGIADVVPIALTPFVVVLLAPRLQKIQTIIPRI
>CP035283.1|QAT48640.1|375857_376637_+|creatininase-family-protein
MIAKWENLTRDEIAQLDKSRTIVLLPTGATEQHGPHLPVGTDSIILSALIDLIVEKQDFDEGNLIFAPQLCVGKSNEHMGFPGTITFGTQTYYSLLHDIAAAVSKSGFQKLVLFNSHGGNTDMLNLISRDMRIDFGLDVFVFDWWFTPFWNKGLKGLKQSGTYGVFHACELETSLMLAIRPETVHMELAVDEDPVESLRDNDYVTILGPYTAGWKTSDVTKSGVIGAPTYATAEKGKKLLDYAVGELHNIFAAFLKTIY
>CP035283.1|QAT48639.1|375022_375838_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MNDFLQYVEMDSFLHRLDPRTKFFFFIVISVLTSFVKSGVSLLFLFLVFLVIWGTSHIGKYIAVLAAKVKVLLLFIFLLWLVLGAFTVNIGPVLSRRAFSLFGRDCIFSLEWFDLYKGAVFDMRVFLMISVFYTVILSTNFSQIISGLRLWKVPYSVAFGVGLVFQIIPMIIKEFDTIMEAQSSRGLEVEKCGAFAKMKNYVIVSLPLLFRVLGKGHSISLAMHYYKLDFKVRRSSYKVIRPTWRDTAFVAVTVVSTAAAVVLQIMFYIKL
>CP035283.1|QAT48638.1|373337_375026_+|ABC-transporter-ATP-binding-protein
MGFSIKNISYQYKPNAEAVLKDVSFEIREAQVTAIVGPSGCGKTTLVNILSGVIPELMPMGVYEGSFDVGKDISISVVSQSPENQLFGYGVEDAISFGIENMGLESGKIAERVEYVLDLLNIQHLRRRSVATLSGGQRQAVCIASVLAMRPDILIMDEPVSSLDPEGKRMIQSILNQLRETGQTTVIVDNNLDWFSGIVDHVIGLSEGRVVFNGTKDEFFRDFAIQETLGVTVPQEVEIYRRLSEKIEGLELFDTVDGAKRVLGRYLPSGKPRPIPAASSDDGDEILRAEGISKTFQDGFHALIDVSAGFGPGKVISIIGQNGSGKTTFVKHLNGLYRPTEGTVRYKGVGTAGKSVAQISRDIILVFQNPEHMLFEESVMKELTFCARAQGVEFSEAEALDVLERYGLLEVKDELPLNLSMGKKHLLTILSVLFSSAEVVILDEPTLGMDLHIKSQLENIIRNLAQRGKTVIIISHEIPLVFQVSDRILVLNNGVKLAYASRASMAERDELFEKINISLPPVVLLSKYFGFSEVCCDVGSFVGEAAGRISACRSDAAWRDQE
>CP035283.1|QAT48637.1|372747_373302_+|adenine-phosphoribosyltransferase
MNETYELHVAGLTRKLPVIRITDSLSIASFVILGDAELVIRAAQELSGKIPEVDYLITAEAKGIPLVQELARLLGMSRYFVARKSIKPYMTDPVVTEVYSITTQAKQILCLEKEESELIRGKRILIVDDVISTGDSVKAMEALVKKAGGKIAGKAAILAEGDSANRSDIIFLEKLPVFPVRPSR
>CP035283.1|QAT48636.1|371358_372387_+|class-B-sortase
MKIRSPKFSRRFRRIGSAVRRGADRLKREAFRRTALLKEAAFRKTVLLKEASFRQNAWHAVFFLSLCAFAVCCGILFHRLYTLPKQSDEGLAKARSLYRGASSSVPQSSSSASFSSAPEEKKLSFSELQAANRDVKGWITIPGTAIDDPVLCPPKDRPDYYLTHDWEGNETKYGSIFLYSGSTSQKNIILYGHSMKDGRMFAPLLDYQEPRFYDLHPVIQFRLGNDTAAWKIFAVIKVNTDPSQGEPFDYQKTKFASPKDFSDFLGRVRIRSVLNIPVDLKTSDTLLTLSTCSYEFDGFRTVIFARRLRRGENASVDTPKVSENAGALYPDCWYAKFGGKRP
>CP035283.1|QAT48646.1|383581_384367_+|2-hydroxyglutaryl-CoA-dehydratase
MFTLGVDIGSTTAKAVILKDGKDIVSSSIVVATVGTDGVSRAMENALRESGVRREEIRFTVATGYGRKTFAGADLQLSELTCHAVGVHREFGDVRTVIDIGGQDAKVLSLNEEGRMANFVMNDKCAAGTGRFLDVMANILHLDISQLEVEAARAVHPANISSTCTVFAESEVISQLASGVRIPDLVAGICQSVAARVASLVKRVGVREQVCMSGGVARNAGVRNAMEKELGVRIVYSEHAQLMGALGAALYAYDKVQNDNL
>CP035283.1|QAT48647.1|384382_385633_+|2-hydroxyacyl-CoA-dehydratase
MGEEVKKKRPAPDPNSAKYKLGQIAAKAYSDCMEAKARGEMVGWCASNFPVEIPETLGLSVCYPENQAAAIAARGGGERMCSESEGDGYSNDLCAYARVSLAYMKLKDAPEQNMPMPDFVLCCNNICNCMIKWYENIARELDIPMIMIDIPFNPDYEVSDAETEYIRAQFWGAIHQLEKITGKKWSDERYKEVMEISGRSSRAWLAATSCAKYLPSPFNGFDLLNHMAVMVTARGKKEAAEAMETLLKEYEDNHEKGDSTYHGEEKYRIMFEGIACWPWLRVTSTGLKSRGINMVTTIYADAFGFIYDDFDGMCRAYARVPNAMNLELSRDKRIKLCKDNHVEGLLVHTNRSCKLWSGFMAEMSRQIGRACDIPVVSFDGDQADPRNFSEAQYDTRVQGLMEIMEANKGGRSDGNR
>CP035283.1|QAT48648.1|385619_386732_+|2-hydroxyacyl-CoA-dehydratase
MAIDELLAQFHEIAASPRKQLGKYLAQGRKVVACAPVYTPEEIIHSMGLVPMGVWGAEMEVHEAKKYYPAFICSIMQTVLELGITGKFEGISAIVIPSLCDSLKSLGQNWKYAVPGIPFIPMTYPQNRKPDYGVKFTKASYEKVISDLEIATGAKFSEILLAESNRIYNEHNAAMREFAETAADHAITAVQRSDVFKSAWFMLKEEHTALVRQLTAELKKAPADEGKVRVVTSGILADSPGLLEIFDKNGIKIVADDVAQESRQYRTDVPEKPNPLDALAQKFADMDNCSVLYDRDKKRVGFIVDLAQKHNAAGVIVLMTKFCDPEEFDYVPIKRACDAAGLRNVNIEVDCQMVNYEQAGTMLQAFKEMG
>CP035283.1|QAT48649.1|386807_387974_+|hypothetical-protein
MINKNKMPVAIGVAFVWFTTQFGGGFASGAQLYSYFVKFGIWALITPVLAQAFGAFFQWYGLRYAKRHETYDYRTFTDKFYGDFGEKARPIFSNLYELVYLFTICLAPSVAFATGGATLHALTGIPYIVCTVIIGLIIFVLTIYGTDLVRAAASTVSVVIIAGLLLVYVPNIFAQWGTISANIGQMAAAPAPAGPAFWRCFVYAAFQLASIGLLMQHAEPFKDEKEAKKSMVYGFIVNAFIIFMCTVGLIAIVNNPDLKTAQVPTLLMVQTGVGASFLTPVISILIILGAVSTAVNMIAGVIARYVNAWNRKDASPEVSKQNLMKRTIIIAVIFTLLTFAIAQFGLIPLVNTGYGYLGYLTIIVVVVPFVVHMIMTKNGKIDAEYKKN
>CP035283.1|QAT48650.1|388012_389254_+|CoA-transferase
MSKPLEGVRVVELANFIAAAAAGRFMADLGADVVKIEAAKGDPLRYTAPSEGRPLDMVENTTWDLENGNKRCISLNMKDPAGKEAFFKLLDTADVLITNWRVQALQKLGLDYDSLKGRYPKLVYAICTGYGEYGPDRNLPGFDFTAFFARGGYLDSLRQKGTVPMNVVPGLGDHNVGMNLAAGILAALYQAKIKGVGEKVETSLFESSIYNMGMMVEASNYEGIAQQYPIDVRKSANPFNAAWRTKDDRFIQTCMPDYNTYYKAFITAVGREDLVGSENYFPILTCQEKGLTSEVYDIVMDAFSKKTVEEWKEILVAADVPFSVAQNWVEIRNDKQAEANNCFYDMKYPNGHIRRLVRLPVKFQEMGVPDYRPGPMIGEQGPEILKELGYDDGQVRDMLEKGSLYVWKDEHKK
>CP035283.1|QAT48651.1|389351_390971_+|AMP-binding-protein
MELISKTIGECLKERVHLSGRCTAIEMGGFHCTFEQLDRFSDFAAARMEEDGVGKGTHAGIWCANGPDWVLAFLALAKIGAVPVLINTCFRDAEVTRVLNYADVEVLYYGAGNESLIERIRRKTARVKKFIPIGEKGAGTWAGSLVGTAPPPPADLKRVEGKKKAVRPEDPACMIFTSGTTSFSKGVLLSHYSLVNNSRAMVEAMHWKEDDKMCLTVPLFHCFGITAGILACLLSGAEMDLLPCFKTAYVWDALERGRCTILNGVPSMFLALIRKSEHCGRRADTLRSGIIAGSPVTPEEYAEICRRFPQMHLQPSYGQTETSPCVTIAGWDDPGEKKGASAGRLIDHVSARIADLKTGGVLGRDLDGEIQVKGYNVMLGYYRLPEVTAGAFTEDGWLRTGDIGNFDGSGELHVTGRLKEMIIRGGENISPREIERVIKRLKWVDQVKVVGVPADVLQEEIAACIIPRQGCGINKDELVDFLKPRLARYKMPAYILEFDGFPVNASGKIDLKGLKSKAAAMAGEEKRVRKDGGCAKMKF
>CP035283.1|QAT48652.1|391013_392162_+|acyl-CoA-dehydrogenase
MADAYFTEQHELIRKLASEFSEKEFTKDVLDQVEATGVFPEELLDKMAAAGFFGIKIPKELGGQGADARAYVLVMEEVARVSGIASIYVSTPNSLSGGPLLLAGNDEQKAKYLTPVVTGKKKLAFALTEPGAGSDASGMVTSAVKEGDHYILNGRKCFITMAPLSDYAVVFAKTDMKKGNKGISAFVIDMKAPGVSCGKPEDKMGIVGCATSDIILENVAVPEADRLGEEGEGFKIAMKTLNTGRLGVAAQSIGVAQGCLDAAVEYAKERKQFGRRIGDFQAIGFMIAEMATKLEAAKQLTYKAAYLMDTKQDATLNASMAKYYASEVCNEIAAKAVQIHGGYGFIKDYKVERMYRDCRVFTIYEGSSQVQEIVISRQLLKK
>CP035283.1|QAT48653.1|392179_392965_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MKILVCVKQVPDTNEVKIDPVKGTLIREGVPSILNPDDANALEAALRIKDRDPGTRVAALTMGPPQAAYMLRECLAMGADEAYLLSDRAFGGADTCATSTTIAAGIRKVPGVDIIFAGRQAIDGDTAQVGPQVAQRLGIPVVTYVQDIRLGDGKATVQRQMEDGYERIEVRTPCLLTCVKELNEPRYMSVGRIVDAYQKEIAVWDHAAVGLDGKDCGLNASPTQVFRSFTPPQKGKGEMLAGSVGEMAKSLIGKLDEKHLI
>CP035283.1|QAT48654.1|392985_394176_+|electron-transfer-flavoprotein-subunit-alpha
MAVEVLKDQCRGCTKCVKSCPFEAITMENRIAVIGPACTGCGQCVEACPFHAIEKTEDGRAAADLGAYRNVWVFAEQREGKLMQVAVELLGEGRKLAGALGCELCAVLCGSGVEPLAGELFEYGADKVYYADAPELKQYTTDAYTKVIQEAIERYKPEIVLLGATHIGRDLGPCLAVRCQTGLTADCTKLEINPDTKKIMQTRPAFGGNLMATILCPSHMPQMSTVRPGVMEKAVRVPGRKGGLIRLDVHFAEGDIRTKVLEAVKTVREAVSLTDADIIVSGGMGLGNAEGFQLLKQLTQRLGGTVASSRAAVDAGWIDHAYQVGQTGTTVKPKIYFACGISGAIQHVAGMQNSGMIVAVNTNENAPIFDIADIGIVGDLYQVIPAIMEELDKRPV
>CP035283.1|QAT48655.1|394271_395414_+|acyl-CoA-dehydrogenase
MKTPFFTEDHEDIREMARDFAEKALAPIAADVDKNDAFPREVVETMAGMGFLGLKIPEEYGGSGMDMRSYVSVMEEVARKCATATIYISSANSLSTAPIILSGTEEQKRKYLPGVASGESIIAFGLTEPGAGSDAASLATKAVKDGDDYILNGRKCFITFAPVADYTTVYAKTSPEKGAKGITAFLVDMKLPGVSTGKPEEKMGQRGVPVSDVVLDDVRVPADCILGEVDMGFINAMKTLSVGRVGVASMSLGIAQEALDLAVEYTKARVQFGKPLAKNQALRFMMADMETKLNAARMLTYNAAWMMDSKQDATKAASMAKYYAAESAFDIVNKSLQLHGGYGYSKEYEIERLYRDIRITSIYEGSSQVQQMVIAGQLLK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

300889 : 307711

Faecalibacterium_phage(22.22%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT48555.1\|300889_301402_+	siphovirus Gp157 family protein	A6M981	Geobacillus_virus	2.3e-19	39.6
QAT48556.1\|301410_302061_+	hypothetical protein	S5MBS0	Brevibacillus_phage	5.7e-39	49.1
QAT48557.1\|302057_302594_+	hypothetical protein	A0A075KQ97	Lactobacillus_phage	1.5e-13	29.5
QAT48558.1\|302584_303430_+	adenylyl-sulfate reductase	NA	NA	NA	NA
QAT48559.1\|303426_303723_+	hypothetical protein	A0A2K9V430	Faecalibacterium_phage	5.3e-16	52.1
QAT48560.1\|303751_304402_+	hypothetical protein	A0A2K9V4F4	Staphylococcus_phage	3.0e-48	45.3
QAT48561.1\|304401_304839_+	single-stranded DNA-binding protein	A0A2K9V463	Faecalibacterium_phage	4.7e-21	42.7
QAT48562.1\|304848_305214_+	hypothetical protein	NA	NA	NA	NA
QAT48563.1\|305225_306014_+	hypothetical protein	H7BWC5	unidentified_phage	4.2e-36	35.9
QAT48564.1\|306010_307228_+	hypothetical protein	D2XR44	Bacillus_phage	1.2e-26	27.3
QAT48565.1\|307366_307711_+	DUF1064 domain-containing protein	A0A2H4J891	uncultured_Caudovirales_phage	2.0e-11	45.5

DBSCAN-SWA_2

310748 : 319359

Streptococcus_phage(37.5%)

portal,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT48574.1\|310748_311303_+	hypothetical protein	A0A0A0RNF3	Bacillus_phage	6.8e-33	44.7
QAT48575.1\|311299_311515_+	XRE family transcriptional regulator	A0A139ZPJ2	Marinitoga_camini_virus	4.2e-07	43.5
QAT48576.1\|311511_311877_+	hypothetical protein	NA	NA	NA	NA
QAT48577.1\|312527_313019_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.9e-18	42.7
QAT51192.1\|312987_314259_+\|terminase	PBSX family phage terminase large subunit	S6AVV7	Thermus_phage	9.3e-102	47.6
QAT48578.1\|314263_315808_+\|portal	phage portal protein	Q708N3	Streptococcus_phage	1.6e-63	32.9
QAT48579.1\|315804_316002_+	hypothetical protein	NA	NA	NA	NA
QAT48580.1\|316001_317054_+	hypothetical protein	Q20DD6	Lactobacillus_phage	1.3e-27	26.7
QAT48581.1\|317294_317714_+	hypothetical protein	NA	NA	NA	NA
QAT48582.1\|317838_318402_+	phage scaffold protein	A0A1Z1LZK8	Bacillus_phage	6.3e-18	41.0
QAT48583.1\|318417_319359_+	hypothetical protein	A0A1S5SA65	Streptococcus_phage	8.9e-33	33.3

DBSCAN-SWA_3

349092 : 357081

Erysipelothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT48619.1\|349092_349296_+	hypothetical protein	A0A0C5AEJ6	Paenibacillus_phage	9.5e-17	62.7
QAT48620.1\|350097_350283_+	hypothetical protein	NA	NA	NA	NA
QAT48621.1\|350676_351081_+	hypothetical protein	NA	NA	NA	NA
QAT48622.1\|351153_351387_+	hypothetical protein	A0A2I4R673	Erysipelothrix_phage	2.7e-15	60.3
QAT48623.1\|351349_351667_+	rRNA biogenesis protein rrp5	A0A2K5B2A7	Erysipelothrix_phage	2.0e-13	49.5
QAT48624.1\|351760_353356_+	recombinase family protein	Q6DMS5	Streptococcus_phage	2.3e-150	53.5
QAT51194.1\|353741_354752_+	recombinase family protein	A0A1B0RXA2	Streptococcus_phage	5.3e-100	53.1
QAT48625.1\|354766_355189_+	hypothetical protein	NA	NA	NA	NA
QAT51195.1\|355401_357081_-	DUF4368 domain-containing protein	K4ICM1	Acidithiobacillus_phage	1.5e-11	24.9

DBSCAN-SWA_4

821977 : 832586

Erysipelothrix_phage(71.43%)

terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT48998.1\|821977_824500_-	cation-translocating P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	4.7e-73	30.4
QAT48999.1\|825165_825480_+	ArsR family transcriptional regulator	NA	NA	NA	NA
QAT49000.1\|826053_827286_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.3e-185	76.2
QAT49001.1\|827260_828442_-	methionine adenosyltransferase	A0A2K5B278	Erysipelothrix_phage	1.8e-171	77.3
QAT49002.1\|828445_828997_-\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	2.9e-92	88.5
QAT49003.1\|829206_829887_+	DUF421 domain-containing protein	NA	NA	NA	NA
QAT49004.1\|829891_830245_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	1.0e-58	85.5
QAT49005.1\|830351_830786_-	hypothetical protein	NA	NA	NA	NA
QAT49006.1\|830775_830970_-	hypothetical protein	A0A2K5B274	Erysipelothrix_phage	9.1e-09	47.9
QAT49007.1\|831044_832586_-	DEAD/DEAH box helicase	Q6DMV7	Streptococcus_phage	1.6e-156	59.6

DBSCAN-SWA_5

1406904 : 1457232

Erysipelothrix_phage(50.0%)

capsid,portal,tRNA,terminase,tail,head,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT49501.1\|1406904_1408374_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
QAT51257.1\|1408373_1410062_+\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	4.7e-186	58.7
QAT49502.1\|1410138_1410414_+	hypothetical protein	NA	NA	NA	NA
QAT49503.1\|1410621_1411146_+	hypothetical protein	NA	NA	NA	NA
QAT49504.1\|1411225_1411915_+	hypothetical protein	NA	NA	NA	NA
QAT49505.1\|1412049_1412880_+	hypothetical protein	NA	NA	NA	NA
QAT51258.1\|1412940_1413948_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
QAT49506.1\|1414083_1414281_+	DUF951 domain-containing protein	NA	NA	NA	NA
QAT49507.1\|1414321_1415413_+	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	2.8e-06	39.7
QAT49508.1\|1415414_1416437_+	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	3.8e-45	38.0
QAT49509.1\|1416402_1417035_+	dephospho-CoA kinase	NA	NA	NA	NA
QAT49510.1\|1417031_1417598_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	3.8e-15	38.4
QAT49511.1\|1417612_1419025_+	aminopeptidase	NA	NA	NA	NA
QAT49512.1\|1419300_1419675_+	response regulator	NA	NA	NA	NA
QAT49513.1\|1419677_1420304_+	chemotaxis protein CheC	NA	NA	NA	NA
QAT49514.1\|1420303_1421251_+	diguanylate cyclase	NA	NA	NA	NA
QAT49515.1\|1421367_1421574_+	DUF1858 domain-containing protein	NA	NA	NA	NA
QAT49516.1\|1421548_1422328_+	SAM-dependent methyltransferase	NA	NA	NA	NA
QAT49517.1\|1422340_1423117_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
QAT49518.1\|1423135_1424896_+	fibronectin/fibrinogen-binding protein	NA	NA	NA	NA
QAT49519.1\|1424926_1426519_+	O-antigen polysaccharide polymerase Wzy	NA	NA	NA	NA
QAT49520.1\|1426515_1427766_+	glycosyltransferase	NA	NA	NA	NA
QAT49521.1\|1427728_1428895_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
QAT49522.1\|1428923_1430183_+	hypothetical protein	NA	NA	NA	NA
QAT49523.1\|1430248_1430926_+	DUF421 domain-containing protein	NA	NA	NA	NA
QAT49524.1\|1430922_1431303_+	DUF4363 family protein	NA	NA	NA	NA
QAT49525.1\|1431346_1432603_-	glycosyltransferase	NA	NA	NA	NA
QAT49526.1\|1432873_1433938_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-10	28.2
QAT49527.1\|1433382_1435164_+	glycosyltransferase	NA	NA	NA	NA
QAT49528.1\|1435211_1436669_-	radical SAM protein	NA	NA	NA	NA
QAT49529.1\|1437020_1438478_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
QAT49530.1\|1438492_1439860_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
QAT49531.1\|1440020_1440689_+	hypothetical protein	NA	NA	NA	NA
QAT49532.1\|1440815_1441238_-	asparagine synthase	NA	NA	NA	NA
QAT49533.1\|1441464_1443174_-	hypothetical protein	A0A217ER40	Bacillus_phage	1.7e-05	31.3
QAT49534.1\|1443187_1445701_-	hypothetical protein	A0A0A7RUI9	Clostridium_phage	4.4e-71	42.5
QAT49535.1\|1445700_1446408_-\|tail	phage tail protein	NA	NA	NA	NA
QAT49536.1\|1446407_1448699_-\|tail	phage tail protein	A0A2K5B297	Erysipelothrix_phage	4.1e-23	65.6
QAT49537.1\|1448778_1449186_+	transcriptional regulator	NA	NA	NA	NA
QAT49538.1\|1449239_1449842_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
QAT49539.1\|1450038_1450431_-	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	1.6e-44	74.6
QAT49540.1\|1450446_1451046_-\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	4.1e-76	73.1
QAT49541.1\|1451048_1451390_-	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	1.7e-26	52.3
QAT49542.1\|1451386_1451818_-	HK97 gp10 family phage protein	A0A2K5B292	Erysipelothrix_phage	1.8e-41	58.6
QAT49543.1\|1451829_1452165_-\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	1.2e-29	56.9
QAT49544.1\|1452168_1452480_-\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	2.6e-37	74.0
QAT49545.1\|1452481_1453669_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	1.6e-156	68.2
QAT49546.1\|1453682_1454363_-\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	3.0e-67	60.5
QAT51259.1\|1454359_1455601_-\|portal	phage portal protein	Q6DMU2	Streptococcus_phage	5.2e-158	66.0
QAT49547.1\|1455600_1457232_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.0e-214	67.0

DBSCAN-SWA_6

1793129 : 1802037

Synechococcus_phage(14.29%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT49834.1\|1793129_1793774_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.2e-24	37.8
QAT49835.1\|1793767_1794802_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	4.6e-67	44.8
QAT51284.1\|1794829_1795327_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.1e-21	45.2
QAT49836.1\|1795692_1796607_-	SPFH/Band 7/PHB domain protein	A0A0G2YDT0	Acanthamoeba_polyphaga_mimivirus	1.4e-19	32.9
QAT49837.1\|1796626_1797055_-	NfeD family protein	NA	NA	NA	NA
QAT49838.1\|1797196_1797658_-	helix-hairpin-helix domain-containing protein	A0A1V0SDW0	Indivirus	7.0e-07	53.2
QAT49839.1\|1797694_1798612_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	6.9e-06	24.5
QAT49840.1\|1798613_1799093_-	signal peptidase II	NA	NA	NA	NA
QAT49841.1\|1799250_1802037_-\|tRNA	isoleucine--tRNA ligase	H2EEZ0	Moumouvirus	5.6e-83	26.7

DBSCAN-SWA_7

1835629 : 1844754

Streptococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT49865.1\|1835629_1837753_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.0e-117	35.7
QAT49866.1\|1837909_1839085_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	5.2e-14	29.6
QAT49867.1\|1839844_1840225_+	ArsR family transcriptional regulator	E4ZFI8	Streptococcus_phage	5.9e-12	32.1
QAT49868.1\|1840457_1840787_+	FMN-binding protein	A0A2P0ZL82	Lactobacillus_phage	7.9e-05	31.6
QAT49869.1\|1841011_1841431_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	1.0e-44	60.6
QAT49870.1\|1841633_1842146_+	ferritin-like domain-containing protein	NA	NA	NA	NA
QAT49871.1\|1842225_1844754_-	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	2.1e-68	29.6

DBSCAN-SWA_8

2357031 : 2364112

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT50313.1\|2357031_2357781_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-32	36.1
QAT50314.1\|2357996_2358716_+	response regulator transcription factor	NA	NA	NA	NA
QAT50315.1\|2358712_2359945_+	GHKL domain-containing protein	X5JAC0	Clostridium_phage	2.7e-21	26.1
QAT50316.1\|2360696_2361800_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	6.1e-49	35.6
QAT50317.1\|2361781_2362420_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.8e-38	40.1
QAT50318.1\|2362431_2363631_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.0e-89	45.4
QAT50319.1\|2363644_2364112_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.5e-44	57.6

DBSCAN-SWA_9

2873057 : 2881959

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT50774.1\|2873057_2874473_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.8e-38	32.8
QAT50775.1\|2874462_2875155_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.2e-36	38.4
QAT50776.1\|2875233_2875929_-	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	2.0e-29	47.9
QAT50777.1\|2876083_2876947_+	phospholipase	NA	NA	NA	NA
QAT51353.1\|2876992_2877910_-	FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.2e-53	40.1
QAT50778.1\|2877955_2878501_-	glutathione peroxidase	A0A1S7DLQ4	Molluscum_contagiosum_virus	3.1e-14	33.3
QAT50779.1\|2880049_2880262_+	hypothetical protein	NA	NA	NA	NA
QAT50780.1\|2880348_2881959_-	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	9.3e-14	33.7

DBSCAN-SWA_10

2964091 : 3044616

Erysipelothrix_phage(59.09%)

holin,capsid,portal,tRNA,terminase,tail,head,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAT50874.1\|2964091_2965498_-\|tRNA	cysteine--tRNA ligase	A0A2L2DK39	Acanthamoeba_polyphaga_mimivirus	1.0e-45	29.8
QAT50875.1\|2965512_2966187_-	serine O-acetyltransferase	NA	NA	NA	NA
QAT50876.1\|2966523_2967126_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
QAT50877.1\|2967122_2968469_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
QAT51357.1\|2968487_2968904_-	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
QAT50878.1\|2968866_2969514_-	regulatory protein RecX	NA	NA	NA	NA
QAT50879.1\|2969510_2970665_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.3e-121	63.2
QAT50880.1\|2970755_2971559_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
QAT50881.1\|2971573_2972428_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
QAT50882.1\|2972427_2973393_-	DUF1385 domain-containing protein	A0A0K2CP67	Brevibacillus_phage	4.1e-09	36.4
QAT51358.1\|2973593_2975024_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.3e-38	35.5
QAT50883.1\|2975125_2975836_-	response regulator transcription factor	NA	NA	NA	NA
QAT50884.1\|2975857_2977207_-	VCBS repeat-containing protein	NA	NA	NA	NA
QAT50885.1\|2977553_2978144_+	PadR family transcriptional regulator	NA	NA	NA	NA
QAT50886.1\|2978140_2979763_+	NAD(P)H dehydrogenase	NA	NA	NA	NA
QAT50887.1\|2979888_2981160_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
QAT50888.1\|2981258_2982191_-	1-phosphofructokinase	NA	NA	NA	NA
QAT50889.1\|2982315_2983794_-	4-alpha-glucanotransferase	NA	NA	NA	NA
QAT50890.1\|2983836_2984943_-	hypothetical protein	NA	NA	NA	NA
QAT50891.1\|2985079_2986267_-	hypothetical protein	NA	NA	NA	NA
QAT50892.1\|2986377_2986722_-	transcriptional regulator	NA	NA	NA	NA
QAT50893.1\|2986877_2987273_+	hypothetical protein	NA	NA	NA	NA
QAT50894.1\|2987347_2987800_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
QAT50895.1\|2987844_2989356_-	AAA family ATPase	H6W7S5	Escherichia_phage	1.2e-07	24.3
QAT50896.1\|2989345_2990707_-	metallopeptidase	NA	NA	NA	NA
QAT50897.1\|2990730_2991708_-	hypothetical protein	NA	NA	NA	NA
QAT50898.1\|2991730_2992750_-	M42 family peptidase	NA	NA	NA	NA
QAT50899.1\|2992837_2993458_-	hypothetical protein	NA	NA	NA	NA
QAT50900.1\|2993756_2994614_+	patatin family protein	NA	NA	NA	NA
QAT50901.1\|2994786_2995251_+	LytTR family transcriptional regulator	NA	NA	NA	NA
QAT50902.1\|2995240_2995957_+	hypothetical protein	NA	NA	NA	NA
QAT50903.1\|2995985_2996405_+	NUDIX domain-containing protein	NA	NA	NA	NA
QAT50904.1\|2996786_2997656_+	hypothetical protein	NA	NA	NA	NA
QAT50905.1\|2997668_2997947_+	hypothetical protein	NA	NA	NA	NA
QAT50906.1\|2998548_2999097_+	hypothetical protein	NA	NA	NA	NA
QAT50907.1\|2999491_2999860_+	DUF488 family protein	NA	NA	NA	NA
QAT50908.1\|3000068_3001967_+	cation-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.9e-101	35.9
QAT50909.1\|3002033_3002249_+	copper chaperone	NA	NA	NA	NA
QAT50910.1\|3002269_3002590_+	iron-sulfur cluster repair di-iron protein, ric	NA	NA	NA	NA
QAT51359.1\|3002661_3003324_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
QAT50911.1\|3003400_3004591_+	anaerobic nitric oxide reductase flavorubredoxin	NA	NA	NA	NA
QAT50912.1\|3004663_3006232_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	3.5e-159	56.1
QAT50913.1\|3006218_3006650_-	recombinase	A0A2K5B2B3	Erysipelothrix_phage	3.6e-21	41.5
QAT50914.1\|3006650_3008222_-	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	5.5e-144	50.1
QAT50915.1\|3008282_3008489_-	hypothetical protein	A0A2K5B2B1	Erysipelothrix_phage	3.4e-06	49.1
QAT50916.1\|3008606_3009530_-	LysM peptidoglycan-binding domain-containing protein	H7BVK7	unidentified_phage	2.1e-50	48.2
QAT51360.1\|3009526_3009943_-\|holin	holin	A0A2K5B2A2	Erysipelothrix_phage	1.7e-52	74.3
QAT50917.1\|3010023_3011727_-	hypothetical protein	NA	NA	NA	NA
QAT50918.1\|3011743_3012247_-	hypothetical protein	E2ELJ8	Clostridium_phage	4.3e-34	46.1
QAT50919.1\|3012247_3013288_-	hypothetical protein	H7BUP3	unidentified_phage	7.5e-41	32.8
QAT50920.1\|3013338_3014190_-\|tail	phage tail family protein	A0A1P8BL47	Lactococcus_phage	4.6e-28	29.6
QAT50921.1\|3014200_3016627_-\|tail	phage tail protein	A0A2K5B297	Erysipelothrix_phage	4.4e-76	66.3
QAT50922.1\|3016719_3017088_-	hypothetical protein	NA	NA	NA	NA
QAT50923.1\|3017159_3017351_-	hypothetical protein	A0A2K5B296	Erysipelothrix_phage	7.3e-11	68.3
QAT50924.1\|3017347_3017737_-	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	9.6e-42	69.0
QAT50925.1\|3017750_3018350_-\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	1.9e-73	70.5
QAT50926.1\|3018353_3018692_-	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	5.8e-27	50.9
QAT50927.1\|3018688_3019123_-	HK97 gp10 family phage protein	A0A2K5B292	Erysipelothrix_phage	3.7e-42	61.8
QAT50928.1\|3019124_3019460_-\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	4.3e-30	58.7
QAT50929.1\|3019462_3019780_-\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	6.0e-34	71.0
QAT50930.1\|3019849_3021037_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	2.9e-121	56.7
QAT50931.1\|3021057_3021783_-\|protease	Clp protease ClpP	A0A2K5B288	Erysipelothrix_phage	6.5e-84	69.0
QAT50932.1\|3021779_3023039_-\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	3.9e-161	65.8
QAT50933.1\|3023035_3024646_-\|terminase	terminase large subunit	A0A1B0RXJ8	Streptococcus_phage	1.9e-176	57.0
QAT50934.1\|3024736_3025492_-	MerR family transcriptional regulator	NA	NA	NA	NA
QAT50935.1\|3025612_3025846_-	hypothetical protein	NA	NA	NA	NA
QAT50936.1\|3026151_3026328_-	DUF5049 domain-containing protein	NA	NA	NA	NA
QAT50937.1\|3026320_3026551_-	DUF4314 domain-containing protein	A0A2K5B281	Erysipelothrix_phage	5.7e-18	63.2
QAT50938.1\|3026564_3027233_-	virulence protein	A0A2K5B280	Erysipelothrix_phage	1.6e-44	44.2
QAT50939.1\|3027370_3028666_-	site-specific DNA-methyltransferase	A0A2I4R670	Erysipelothrix_phage	9.5e-110	49.6
QAT50940.1\|3028669_3029218_-	hypothetical protein	A0A2K5B277	Erysipelothrix_phage	4.0e-17	34.9
QAT50941.1\|3029369_3029720_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	3.5e-35	59.1
QAT51361.1\|3029831_3030251_-	DUF1492 domain-containing protein	A0A2K5B275	Erysipelothrix_phage	1.2e-13	35.5
QAT50942.1\|3030337_3031702_-	DEAD/DEAH box helicase	A0A1X9I6B0	Streptococcus_phage	8.3e-149	58.1
QAT50943.1\|3031682_3031964_-	VRR-NUC domain-containing protein	A0A1W6JQA8	Corynebacterium_phage	1.2e-22	56.0
QAT50944.1\|3032089_3034363_-	DNA primase	A0A1X9I6B6	Streptococcus_phage	1.9e-198	48.4
QAT50945.1\|3034362_3034686_-	hypothetical protein	NA	NA	NA	NA
QAT50946.1\|3034669_3035107_-	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	2.9e-39	52.1
QAT50947.1\|3035189_3037130_-	hypothetical protein	A0A2K5B2B0	Erysipelothrix_phage	1.3e-275	70.3
QAT50948.1\|3037362_3037929_-	DUF2815 family protein	Q6DMW3	Streptococcus_phage	3.2e-70	68.9
QAT51362.1\|3037921_3039070_-	DUF2800 domain-containing protein	M1Q218	Streptococcus_phage	8.6e-123	58.1
QAT50949.1\|3039123_3039474_-	DNA ligase	A0A2K5B2A7	Erysipelothrix_phage	1.2e-14	45.6
QAT51363.1\|3039409_3039628_-	hypothetical protein	NA	NA	NA	NA
QAT50950.1\|3039760_3040285_-	bacterio-opsin activator	NA	NA	NA	NA
QAT50951.1\|3040713_3042606_-	XRE family transcriptional regulator	E4ZFJ9	Streptococcus_phage	4.0e-93	31.1
QAT50952.1\|3042834_3043056_+	XRE family transcriptional regulator	A0A2K5B261	Erysipelothrix_phage	3.8e-19	65.7
QAT50953.1\|3043113_3044616_+	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	9.8e-50	31.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP035283

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection