CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026520	Paenibacillus chitinolyticus strain KCCM 41400 chromosome, complete genome	2 crisprs	csa3,WYL,cas3,cas14j,DEDDh,DinG	0	1	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP026520_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026520_1

1240388-1240476

Orphan

Consensus_repeat	Method
TTGCGGGCATGCGCAGCGGGTATACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026520_1

>merge|CP026520|1|1240388-1240476|CRISPRCasFinder
TTGCGGGCATGCGCAGCGGGTATACGCGCCCGCAGGTGTATGCAAACGCGGCAGCACGCGGTTGCGGGCATGTGCAGCGGGTATACGCG

>CP026520|1|1|1240388-1240476|CRISPRCasFinder
TTGCGGGCATGCGCAGCGGGTATACGCG	CCCGCAGGTGTATGCAAACGCGGCAGCACGCGG
TTGCGGGCATGTGCAGCGGGTATACGCG

Protein	Signature genes	Signature genes Name	Protein_function
CP026520.1\|QAV17161.1\|1230829_1231723_+\|UTP--glucose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|224131
CP026520.1\|QAV17165.1\|1234483_1234915_-\|DUF2621-domain-containing-protein	unknown	unknown	gnl\|CDD\|378554
CP026520.1\|QAV17163.1\|1233304_1233859_+\|VanZ-family-protein	unknown	unknown	gnl\|CDD\|377417
CP026520.1\|QAV17173.1\|1243715_1244354_+\|YigZ-family-protein	unknown	unknown	gnl\|CDD\|224653
CP026520.1\|QAV17175.1\|1245010_1245412_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376651
CP026520.1\|QAV17178.1\|1246530_1247217_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV17167.1\|1236275_1237163_+\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
CP026520.1\|QAV17164.1\|1233948_1234167_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV17179.1\|1247303_1247594_-\|small-acid-soluble-spore-protein	unknown	unknown	gnl\|CDD\|365990
CP026520.1\|QAV17170.1\|1240002_1240320_+\|DUF1255-domain-containing-protein	unknown	unknown	gnl\|CDD\|377724
CP026520.1\|QAV17168.1\|1237285_1237747_-\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV17172.1\|1242163_1243519_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP026520.1\|QAV17176.1\|1245616_1245841_+\|DUF1128-domain-containing-protein	unknown	unknown	gnl\|CDD\|377674
CP026520.1\|QAV17166.1\|1235065_1236193_+\|deoxyribonuclease-IV	unknown	unknown	gnl\|CDD\|179214
CP026520.1\|QAV17174.1\|1244388_1245030_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP026520.1\|QAV17180.1\|1247881_1248898_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133030
CP026520.1\|QAV17177.1\|1246077_1246368_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|215598
CP026520.1\|QAV17162.1\|1231727_1233062_+\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
CP026520.1\|QAV17169.1\|1237901_1239923_+\|transketolase	unknown	unknown	gnl\|CDD\|223100
CP026520.1\|QAV17171.1\|1240903_1241803_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995

Protein	Function_ID	Function_description	E-value
CP026520.1\|QAV17161.1\|1230829_1231723_+\|UTP--glucose-1-phosphate-uridylyltransferase	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	3.52024e-179
CP026520.1\|QAV17165.1\|1234483_1234915_-\|DUF2621-domain-containing-protein	gnl\|CDD\|378554	pfam11084, DUF2621, Protein of unknown function (DUF2621). This family is conserved in the Bacillaceae family. Several members are named as YneK. The function is not known.	1.20908e-91
CP026520.1\|QAV17163.1\|1233304_1233859_+\|VanZ-family-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	5.96737e-14
CP026520.1\|QAV17175.1\|1245010_1245412_-\|hypothetical-protein	gnl\|CDD\|376651	pfam01894, UPF0047, Uncharacterized protein family UPF0047. This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.	9.55694e-55
CP026520.1\|QAV17167.1\|1236275_1237163_+\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	0
CP026520.1\|QAV17173.1\|1243715_1244354_+\|YigZ-family-protein	gnl\|CDD\|224653	COG1739, COG1739, Uncharacterized conserved protein [Function unknown].	1.61042e-59
CP026520.1\|QAV17179.1\|1247303_1247594_-\|small-acid-soluble-spore-protein	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	5.59014e-15
CP026520.1\|QAV17170.1\|1240002_1240320_+\|DUF1255-domain-containing-protein	gnl\|CDD\|377724	pfam06865, DUF1255, Protein of unknown function (DUF1255). This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown.	1.82613e-53
CP026520.1\|QAV17174.1\|1244388_1245030_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.86798e-15
CP026520.1\|QAV17172.1\|1242163_1243519_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP026520.1\|QAV17176.1\|1245616_1245841_+\|DUF1128-domain-containing-protein	gnl\|CDD\|377674	pfam06569, DUF1128, Protein of unknown function (DUF1128). This family consists of several short, hypothetical bacterial proteins of unknown function.	3.22789e-29
CP026520.1\|QAV17166.1\|1235065_1236193_+\|deoxyribonuclease-IV	gnl\|CDD\|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	2.42966e-141
CP026520.1\|QAV17180.1\|1247881_1248898_-\|glycosyltransferase	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.82753e-66
CP026520.1\|QAV17177.1\|1246077_1246368_+\|hypothetical-protein	gnl\|CDD\|215598	PLN03138, PLN03138, Protein TOC75; Provisional.	0.00154092
CP026520.1\|QAV17162.1\|1231727_1233062_+\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
CP026520.1\|QAV17169.1\|1237901_1239923_+\|transketolase	gnl\|CDD\|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
CP026520.1\|QAV17171.1\|1240903_1241803_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	6.03246e-99

>CP026520.1|QAV17170.1|1240002_1240320_+|DUF1255-domain-containing-protein
MSNFEGVTVVKKANVYFEGKVTSRAVLFADGTKKTLGIMLPGEYEFGTDSKEIMEILAGDLSVLLPGESDWTDIQGEGEFTVPANAKFKLKVRTVTDYCCSYIAE
>CP026520.1|QAV17169.1|1237901_1239923_+|transketolase
MSASNTPIQELAVHTIRTLGIDAIEKAKSGHPGIVMGAAPMAYTLFANQMKHNPANPTWINRDRFVLSAGHGSMLLYAILHLTGYDLPMEEIKNFRQWGSLTPGHPEFGHTAGVDATTGPLGQGIGMAVGMAMAEAHLAGLYNREGYPVIDHYTYAICGDGDMMEGVSSEAVSLAATLKLGKLIMMYDSNDISLDGDLHVSFTENVQKRFEAYGWQVLRVEEQNDLEALNRAVEEAKADTTRPTLIEVKTTIGYGSPNKGGKGGHAGPHGSPLGLEEAKLTKEFYKWNYEEDFYVPEEVREHYAAVKEKGIQAEQAWKKQFDDYRKAFPELAEQFELGESGKLPEGWDRDLPVYTPEDKALATRAASGNALNAIAKNVPFFFGGSADLASSNNTEIKNAPIFNAENYAGRNIWFGVREFGMGAALNGISLHGGLRVYGGTFFVFSDYLRPSIRLAALMKQPVIYVFTHDSIGVGEDGPTHEPVEQLAALRVIPGMTVLRPADGNETSEAWRYVMEHNDGPYALILTRQNLPQLEGSAKYARENLSKGAYVVSDAPNGKPDALILATGSEVQHGVAAQKLLAEEGIQVRVVSMPSWELFEKQSQEYKDSVLLPDVKKRLGVEMAYPLGWERYVGDEGSILGISTFGASAPGDLLIKEFGFTAENVAKRVKELLK
>CP026520.1|QAV17168.1|1237285_1237747_-|hypothetical-protein
MSRPFFENGNTLVARGFAFGLVPGAALALFFKAVEFFAGSRVYTLLLNVDFIPGLGGDQPEWFELTLHLAVSVLIGFLYAILLRCTEKPWLPGILLGISPIPLFVPLTQLAVSAKTPVLSDVTAMIWWIAGHLLYGVILAVLGTKALRASKKE
>CP026520.1|QAV17167.1|1236275_1237163_+|formyltetrahydrofolate-deformylase
MAAANTSGAAGKQNRGRMLISCPDRPGIVAAVSKFLSDYGANIVQSDQYTMDPEGGMFFIRIEFDLTDLEQRKPRLEADFAGVAAEFSMDWSLSLASQRKRLAIFVSKEDHCLLELLWHWRAGDLDADIAMVVSNHPDMAPLVEPFGIPYHHIPVTPDTKAEVEKRHLELLEGQVDLIILARYMQIIPPSFIKHYQNRIINIHHSFLPAFVGGKPYAQAHGRGVKLIGATAHYVTEELDGGPIIEQDVQRVSHRDNVDDLKRIGRHIERIVLARAVSWHTEDRILVHQNKTVVFS
>CP026520.1|QAV17166.1|1235065_1236193_+|deoxyribonuclease-IV
MIKIGSHVSFSDKGLLNAAREAVSYGSGTFMIYTGAPQNTRRKPIETQYIEEGREVMQEHGIGEIVVHAPYIINLGSYKDNTYELAVQFLQDEIRRTDYLGVKNIVLHPGAFTDKDAEYGLARISEGLNEVLAGVKDTGVHIALETMAGKGTEMGRSFEELAQIIDKVEDNGRLTVCLDTCHIHDAGYDVVGDLDGVLDQFDRVVGLDRIGVVHLNDSKNPRGASKDRHAPVGAGWIGFEAMNRVVHHEKLLGLPMILETPWIGKDPKTQRPMYEAEIALLSGTVLERFGASFVEDVERLASFFEKKEVDSRGFVLQTWELLKTDAKAKKADGREPMERLYDMIAEERLFPELSEEQINQRLTAWFAGKDLLKSL
>CP026520.1|QAV17165.1|1234483_1234915_-|DUF2621-domain-containing-protein
MNNSLFMWFITFWPLVLIGLMAIGGYFMFRKFLKVLPKADGKSKLDWQNYYVEKSRHMWTDDSKAFLNKLVAPVPGPFRDIAKHSIAAKIGQIALEEEAAEVTREHCIKGYIIATPKRDYRSLMNFLEREKIDYTPYKHLINS
>CP026520.1|QAV17164.1|1233948_1234167_+|hypothetical-protein
MKALDLVYCIHCGSIVSRIQADHIFKTGFYRVSIPLASCKGCAAPNSNTTSCHDLPHHGRLNEYETRLPLMA
>CP026520.1|QAV17163.1|1233304_1233859_+|VanZ-family-protein
MEVILMTHRSRLRFFVLFGLPLLVWMAVIYHFSSEPYSKQNLRPWLKQEFSDKRINQLFSESKIQYNGKEVSIRKSGTWGFVEFFIRKAAHLFVYGVLAVLIARLLHRGLGQSKLAVYVTVILASALFAGLDEFHQSFVSQRTAATEDVILDTCGALLGTAMYYFFLKILQKSRKNAPNYPKTS
>CP026520.1|QAV17162.1|1231727_1233062_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MSTIGVIGTGYVGLVSGTCFSEVGHQVICCDIDEAKIAKLQRAEIPIYEPGLEELVKRNTNLNRLSFSSDIASVIHRSDVIFIAVGTPMSPSGEADLSYVRAAAAAIGQSIRDYKVIVTKSTVPVGTGRLVQEIIRSNQSDPSIPFDVASNPEFLREGSAVHDCMNMERAVIGATSDRAAEIIARLHDPFRTTIFKTSLESAEMIKYAANTFLAAKISFINAIANICERVGADVTEVAKGMGLDSRIGNKFLQAGIGYGGSCFPKDTHALKHIADVSGYDFKLLEAVIETNDKQRMLVIEKLEKAIGNLTDKKIAVLGLAFKPNTNDVREAPSLTLIPKLLEKGARVQAYDPIAVEEARCYLPDSVVYTQDLYDAVRDCDACVILTEWKEVVTMELDHIRELLRKPVIIDGRNCFALERMRQEGFEYYSIGRPEVLAPNAVLSV
>CP026520.1|QAV17161.1|1230829_1231723_+|UTP--glucose-1-phosphate-uridylyltransferase
MTIKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIVEEAIASGIEDILIISGRGKRAIEDHFDKSFELEETLEQKGKLEDLKQIQAISNLANIHYVRQKEPKGLGHAILCAKSFIGQEPFAVLLGDDIVQAETPCTAQLIEVYEKYKSTVVGVQWVADKDVNKYGIVDAGKEIVDRHVIPVRSLVEKPQPSEAPSNYAIMGRYILTPEIFNILETQQPGAGGEIQLTDAIRRLNENRPTFAYEFEGIRYDVGDKLGFIKATIDFALQRPDLSSDLYRYIREIYEKDLILQGG
>CP026520.1|QAV17171.1|1240903_1241803_-|NAD(P)-dependent-oxidoreductase
MKQIGFIGLGTMGAPMALNLLRKGYAVTVYNRSADKAAELVQAGASLAATPAEAVSGAEVLFTMLSNDSAIESVFYGENGVLEKAGEGLTVIDSSTVSPALSQRLHADLGKRGAYFLDAPVTGSKPAAEAATLVFMVGGDRPVFDAQHALLSDLGSKVLYMGPSGSGSYTKLAHNTIVGINAIGLMEGLSIATKAGLAPEQFLQIVQAGSGNSKQAELKGPKILERDFSNQFSLKLMLKDLLLASDLTGKFQLPAPMLHAATTVFQMGLSKGLGEEDLAAAIQCYEEWMNERVEKKGGQ
>CP026520.1|QAV17172.1|1242163_1243519_+|glucose-6-phosphate-isomerase
MTQKLQFDYSKALDFVAQHEIDYLAGPIRTAHDQLHNGTGAGSDYLGWIDLPVAYDKEEFGRIQKAAKQIQSDSEALVVIGIGGSYLGARAAIEMLSHSFYNLLDKDKRKTPAVYFVGQNISSTYVTHLLQLLEGKDFSVNVISKSGTTTEPAIAFRIFRELLEKKYGKEAARKRIYATTDREKGALKQLANGEGYESFVIPDDVGGRYSVLTAVGLLPIAVAGIDIEEMMKGAADAREAFSNPELSENASYQYAAVRNALYRKGKTTEILVNYEPSLHYVSEWWKQLYGESEGKDNKGIFPAAVDFTTDLHSMGQFIQEGTRNLFETVLFVDQSAEEIVIGTDEENLDGLNFLSGKTMDFVNKKAFQGTMLAHSDGGVPNLIVTLPDTSAHTFGYMVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEEDKAKLEARLND
>CP026520.1|QAV17173.1|1243715_1244354_+|YigZ-family-protein
MIASYRTVQKHGADEIIIKRSRFIGQALPVSSEEEALAFIAGVKKEHSMATHNCSAYMIGERNEIQKQSDDGEPSGTAGKPILEVIRNMDLKNVAVVVTRYFGGIMLGAGGLIRAYTDGAVAGIQAALPVYKVSHQELLAEIDYTWLGKVENELRNRNMRMGDTEFTDKVILRCYPLSAEADSFADWFTDLTQGQGNIIRGEHTYIEHSELP
>CP026520.1|QAV17174.1|1244388_1245030_+|TetR/AcrR-family-transcriptional-regulator
MARKAVAQELSRERILEEARELFVTRGYRALTMRSIAKAMGYSHGALYYHFREKAELFNALILEDFSILLQRQRQIIVESAVLGVPLLQKLMMEFIRFGLENPNHYEIMFMIRDEELRQYSRTEQAKCFDLFATVVRQVISGMPDKEDQEYRLPWNLFMSMHGFISHSIHYGQTYELVEQLAEEHVQLLCSNMVSTAARSESSKVSLVNHESA
>CP026520.1|QAV17175.1|1245010_1245412_-|hypothetical-protein
MLHTYDLVTRKRDEMVEITDIVARLVQDMSLEDGTAIVYCPHTTAGITINENADPDVKRDVLMRLDEVFPWEHPRDRHAEGNTAAHLKAMTVGASQTVFIRGGRLQLGRWQGIYFCEFDGPRSRTFTVKLIRD
>CP026520.1|QAV17176.1|1245616_1245841_+|DUF1128-domain-containing-protein
MDLAVWSEQNVEYMFDEIKTKLRMATGGSIKASNFSQEQYEDLKDLYDLVMSKPNFSISEIDAITTELGKLRKA
>CP026520.1|QAV17177.1|1246077_1246368_+|hypothetical-protein
MSSKLRNDASKLVGQNIVAVRKDGSMVRGKLVRIQGNELILEPQEGTAQTKAFVPLVLFDLLAIGTSPFVNGFGYGGGFGGGFGYGGGFGGPGFFW
>CP026520.1|QAV17178.1|1246530_1247217_+|hypothetical-protein
MSRGKNEFDYEKEWERKFGFRSGEIPSFSSIFGGGETLFTELSKRISEDPENTAWLDQWLDKLLRQAMPGYRIPEWMGTDWENEPAGGPAGQNAQGSTMPRGGEKRRASEDHSAAAKPPAAIPIPGLKPVKGLAAGSKKRQTAKVKAAESFAYSITEDGSRLVVIVQQPSGIRPGEIELAADRRSIRLSGSRVGGKQTIRLFRPIRPGSCRMTSEDDSLVIRADLARR
>CP026520.1|QAV17179.1|1247303_1247594_-|small-acid-soluble-spore-protein
MARRRSRRAAVPGSERSLDKLKGQVMRDAGYNVSADQPNLVKYEVARTLGVPLEPGYNGQLRTEDAGKIGGEIGGRMVRELVRMAQKQLAERGGPK
>CP026520.1|QAV17180.1|1247881_1248898_-|glycosyltransferase
MSSPILTIVVPCYNEEEVLPETVSRLSAVLDRLIQEKLVARESVMMLVDDGSKDRTWDLIDQYSRSHDYVTGVKLARNAGHQNALLAGLMTARHTSDIVISIDADLQDDTDAIREFVRKYMEGAEIVYGIRSDRTTDTWFKKTTAESFYKLMLRLGVQIKNNHADYRLMSKRALDYLSRYKEVNVFLRGIVPLLGLRTAEVMYERKERFAGESKYPLRKMLSFALDGITSFSVKPIRMVTVTGFLFSIISLLAGAYAIISKLWGTTASGWTSLILSVWFIGGVQLLALGLIGEYIGKIYREVKHRPLYLIEKSIPTQQDYEGPADFDRIPVGAERAGR

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Crispr_ID: CP026520_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026520_3

3234168-3234402

Orphan

I-C

Consensus_repeat	Method
GTCGCACCCCTTACGGGTGCGTGGATTGAAATAC	PILER-CR
GTCGCACCCCTTACGGGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACCCCTTACGGGTGCGTGGATTGAAATA	CRT

3 spacers

The CRISPR arrays of CP026520_3

>merge|CP026520|3|3234168-3234402|PILER-CR,CRISPRCasFinder,CRT
GTCGCACCCCTTACGGGTGCGTGGATTGAAATACTCTGTATTGGTTTTTTAAACAATGTGTTGGTTACGTCGCACCCCTTACGGGTGCGTGGATTGAAATACGTTCATACATTTTAGGCTCATATGCATCATATAATGTCGCACCCCTTACGGGTGCGTGGATTGAAATCTCCATTTAGATTCAGAAAAGTCTTCATTTGATGCCGCACTCTACAAGAGTGCGTGGATTGAAGCA

>CP026520|3|1|3234168-3234338|PILER-CR
GTCGCACCCCTTACGGGTGCGTGGATTGAAATAC	TCTGTATTGGTTTTTTAAACAATGTGTTGGTTAC
GTCGCACCCCTTACGGGTGCGTGGATTGAAATAC	GTTCATACATTTTAGGCTCATATGCATCATATAAT
GTCGCACCCCTTACGGGTGCGTGGATTGAAATCT

>CP026520|3|3|3234168-3234401|CRISPRCasFinder
GTCGCACCCCTTACGGGTGCGTGGATTGAAAT	ACTCTGTATTGGTTTTTTAAACAATGTGTTGGTTAC
GTCGCACCCCTTACGGGTGCGTGGATTGAAAT	ACGTTCATACATTTTAGGCTCATATGCATCATATAAT
GTCGCACCCCTTACGGGTGCGTGGATTGAAAT	CTCCATTTAGATTCAGAAAAGTCTTCATTTGAT
GCCGCACTCTACAAGAGTGCGTGGATTGAAGC

>CP026520|3|1|3234168-3234402|CRT
GTCGCACCCCTTACGGGTGCGTGGATTGAAATA	CTCTGTATTGGTTTTTTAAACAATGTGTTGGTTAC
GTCGCACCCCTTACGGGTGCGTGGATTGAAATA	CGTTCATACATTTTAGGCTCATATGCATCATATAAT
GTCGCACCCCTTACGGGTGCGTGGATTGAAATC	TCCATTTAGATTCAGAAAAGTCTTCATTTGAT
GCCGCACTCTACAAGAGTGCGTGGATTGAAGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP026520.1\|QAV18875.1\|3238834_3239437_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377395
CP026520.1\|QAV18871.1\|3234819_3235275_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18872.1\|3235518_3236223_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18868.1\|3233201_3233621_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18867.1\|3232915_3233167_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18865.1\|3231892_3232087_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18860.1\|3228656_3228860_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18870.1\|3234456_3234774_+\|resolvase	unknown	unknown	gnl\|CDD\|214861
CP026520.1\|QAV18861.1\|3228883_3229108_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235422
CP026520.1\|QAV18876.1\|3239411_3240134_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18879.1\|3241768_3242548_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18869.1\|3233675_3233969_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18874.1\|3237750_3238752_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18873.1\|3236395_3237730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319271
CP026520.1\|QAV18877.1\|3240313_3240829_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18862.1\|3229137_3229431_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18863.1\|3230482_3231241_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18866.1\|3232374_3232866_+\|hypothetical-protein	unknown	unknown	unknown
CP026520.1\|QAV18864.1\|3231311_3231794_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368215
CP026520.1\|QAV18878.1\|3241232_3241442_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026520.1\|QAV18875.1\|3238834_3239437_+\|hypothetical-protein	gnl\|CDD\|377395	pfam04647, AgrB, Accessory gene regulator B. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein.	1.99036e-05
CP026520.1\|QAV18873.1\|3236395_3237730_+\|hypothetical-protein	gnl\|CDD\|319271	cd16414, dndB_like, DNA-sulfur modification-associated domain. Family of proteins related to dndB. dndB acts in the regulation of DNA modifications, including DNA phosphorothioation. Both have a conserved DGQHR sequence motif. These proteins show similarity to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, and other members of the ParB/Srx superfamily.	6.82387e-07
CP026520.1\|QAV18870.1\|3234456_3234774_+\|resolvase	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	1.87309e-11
CP026520.1\|QAV18864.1\|3231311_3231794_+\|hypothetical-protein	gnl\|CDD\|368215	pfam04970, LRAT, Lecithin retinol acyltransferase. The full-length members of this family, are representatives of a novel class II tumor-suppressor family, designated as H-REV107-like. This domain is the catalytic N-terminal proline-rich region of the protein. The downstream region is a putative C-terminal transmembrane domain which is found to be crucial for cellular localization, but not necessary for the enzyme activity. H-REV107-like proteins are homologous to lecithin retinol acyltransferase (LRAT), an enzyme that catalyzes the transfer of the sn-1 acyl group of phosphatidylcholine to all-trans-retinol and forming a retinyl ester.	5.69169e-22
CP026520.1\|QAV18861.1\|3228883_3229108_+\|hypothetical-protein	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	1.48056e-13

>CP026520.1|QAV18869.1|3233675_3233969_+|hypothetical-protein
MIYSVHCYFHKINSRKAGSKFEGIVFAKNKEHAEEIVRALFSKYPIEIESMSAVGREDRTLDEVYTERPELIGISPERGYLYNEYTHKVRISKYAGK
>CP026520.1|QAV18868.1|3233201_3233621_+|hypothetical-protein
MLKDLSFEEIPKFFEELAMKDTGRFQLSRIYGMAKSFLEQREKEESIEKLIVKDYRSVVNTTIISEDLAIVEAEVRLNKGKETAFYPVVDNKFFNESRSTFDEALLLGFCRKYSGERCDSAIFNMLRMDLYMNRTVDEN
>CP026520.1|QAV18867.1|3232915_3233167_+|hypothetical-protein
MDDNIIRFPVGFYQRKKNELGAKALICEVSPRWMEIVNTSHEKDFIANVMTLGADKKEKKLCELVLLKEDIYKLAELLKTDKT
>CP026520.1|QAV18866.1|3232374_3232866_+|hypothetical-protein
MNVDLSHFTVANIWSIFGLIMDLVGVIFLGFAFFSKSFDDLRKESGTFFNYNPSLFLNLLDQKASGVAGTVALSLGFLQQFIVNIPISTSIPSLVLVAVLLFFNILIVVGLLVCKKYYVLYQLAKIALFWDKGKFQDDVQVKGRAFQEMIIIGKVKMQEIQRR
>CP026520.1|QAV18865.1|3231892_3232087_+|hypothetical-protein
MSRVRYDFDSVLSNAKTFSDGVMADEKIREMTRESIIQMVVSSCFEYRDNEEFRKRVDEYVENK
>CP026520.1|QAV18864.1|3231311_3231794_+|hypothetical-protein
MFCLKYTLTLLSEAIERVTRTTINAVESSQAAPYKAIHAFFGKDPEIVKGDHISVFCGYIHHGIYIGDGMVIHFTKVDGLGIIQMDTIETFKNGKAIEIRNSPLNCSREEAIQKAYSKLYTTGYNLVFNNCEHFVVWCRDGDNKKIYTPSSAAWQVMGNR
>CP026520.1|QAV18863.1|3230482_3231241_+|hypothetical-protein
MFLEDIIKFANENEIIYFINELDPDEIERVNISISSSKENFLKLFLLAKRGNYPVFITESKLTMDEVQSSLISYEDLIKNHLYKTSGNEVKLKITNIVDEYNKVIEDIPVDVTYKVSVVVILSTYYMSIDHFLNDEGAIWDSQLFYSLDELIEEKFGIEEINKLEQNRVIYTEEITQKVQGKWIEHLRNDDEFRGCTNRDLRLAYLSKQWLRFKQTLSDEEKEINSVHPQIVMEQVWKEIKESISISRIKNK
>CP026520.1|QAV18862.1|3229137_3229431_+|hypothetical-protein
MIKRRFLEYEYFKNLLVKQNDGLTEEEAVKVLNEKDLIWGDLTFTFKQQGNGWRTDIYCNNSDTYITPRELNPVEEKWFLDQVTELSMQKYLALQTA
>CP026520.1|QAV18861.1|3228883_3229108_+|hypothetical-protein
MSESNIGVKAMHEIMRKAKKYDELLVFPSIENELQCDFCGKFQSELNKMIAARRVVICNECVEVCNQVLEEDNS
>CP026520.1|QAV18860.1|3228656_3228860_+|hypothetical-protein
MIKYHESIIKRELYKYDDVEERERHHRQMFENGWHCKSQFDFLENYDWSNGTPAAEYLKQEQMDDKK
>CP026520.1|QAV18870.1|3234456_3234774_+|resolvase
MSNSVMIYVRVGTQEQAEEKLGKQIVGCKQFAEDNDKRVIAVFKDVISANQRSDRFENILDEMKNQGINELLVQNWSRVSRNTKIVYEIDQMFRDQGSFIIPIEQ
>CP026520.1|QAV18871.1|3234819_3235275_+|hypothetical-protein
MSTPITLDYLIKNIDQPLMNLLDIKDDFRNETPVEDLFVNPGANRETRVINALRRGGICNLENVMNVKFSYIYRLRNMGKVSITVLLNAIVNHYHINSLIPCLKSRSDYQEEYKNIVCTIEPILLQKISTCMFQNLSLEQQRKLLKLITGQ
>CP026520.1|QAV18872.1|3235518_3236223_+|hypothetical-protein
MSIDDNFKNTKGDIVHATIKSTISAIPAVGGFLSEYFGLVVTSPAEKRKENILVMLDQRLNELNNKIETFDIYSLSNNEAFLSVVLQAINISIRTHQIEKRAALLNAVSNSALTNSIDENRQQMFLSFIDSFNEWHLKILFFLNDPKQNLQKAGHSIDLDKGSIGLVIFQYYPQLSGELEFTKLIMSDLYNRGLISKDSSDLHTIMGGSGMVASRTSALGKQFIQFINTPDELS
>CP026520.1|QAV18873.1|3236395_3237730_+|hypothetical-protein
MTIVCGMKEGVFIMLRDRSELESNLTNAIERIKYKRKNIEEVNKNLSEYDIPSGFFNEIIKNENLLGEIDTAVLCLISMAVFKIDGSDEVRAENYFTEGEISEARKYTGKEVKDVNLPISINSVLQIDHENFVTTIKISEPVKWYHNKIIVYDFETQRSAKYKKGRDGVVPVPDVNLQSVKDIAEHMLNETYLPDMITLNVYSEDFDPITYNPKSKVLTIKEGATISILDGFHRLQGAVRALSVNPDLQQDIILSIRVYDTDTAKKYFGQINTINVVKTERLEQLKQEKVSYVAVKQLQINSDLKGKIASGSKISELAGHYTTTDILANAIDQVFEPKTAFEAKEVGVYLTDFFNNLLGVFDDEFNTKTSLLRQPRMFIGYIVIAKIFKENDVSFSKIKNVIETIIEEVKELDKVVTYNKGASSRLQKLVKDHFEKIDIKSWIS
>CP026520.1|QAV18874.1|3237750_3238752_+|hypothetical-protein
MSNKIYEGGYFNEYQKMRYVNSLPETTSLQARRILSRAKSIEETYGQDLYNFTLDQIENLLHYLNPSTLNASRSNFYMVQNYIRWGIEQDLRDTNINPLDVLAENNYFKKFIDISKKSLYTKDEIDSMISVCVNAQDAFPIIAIFEGVFGKSGYDELLNLKRQSIVSENLISLTDGEHERVINVSSDFMNLMYKALDQKTYIKKNGILKPTMRSSAEANLEQSDYVLRNVITRSQTNGKADKFLIQRRIAAVKSYNDDWVRVLSPYIIRNSGMLYMAKSFYDKHGEIKKDHYEEISEKFGISKVMNNGYEVYNYHRLKEDFLNVETIIKVYEQ
>CP026520.1|QAV18875.1|3238834_3239437_+|hypothetical-protein
MCDLLRTTILKVDNGRSGGRLVYYLAETLTDWILNKDTLNKLKKDELERGLKKIINFGLIILLVLILSVVTNRVIETLLGMVLLGVMRAILGGHHLPSSDLCVLYTVTLIIVIPYIGHAVDDYKLLMDSLSFFLIILFGPFRKGMSFNKNFLLYKIIGLIIVTGNIYIYRSAIISAAIFIQAIHLIYFTKGVHDNHVDCG
>CP026520.1|QAV18876.1|3239411_3240134_+|hypothetical-protein
MTIMLIAARYIFLSFLEFSALIVLSLTIFGFKLQYYKREILFTSLLMSVLSFLLYEYDLLAVMTIVQIGALILLIRNVFKEKNWLYSTWVVIAGNVFYVLIQTVYVHLSVRSGFFSTFEEATLPMNYKSDISQVICSLIAYTISVYIMIMKQGFAFGFRSIDKKTTIYFHVSLFIILILSAGYTLVDTPVKYGSYYMYSIAIFTLFCLFLYFSYRRNSDETSYHISKFESKNLKGGPINE
>CP026520.1|QAV18877.1|3240313_3240829_+|hypothetical-protein
MSIIKFVREALFNKVGSLLCESDVLEIAEKVNSEYKPRTIMTVEDNALIWIDINDILFVDKPGKETMVHTITKTYKYHDKHLDLIGMISEEEGFLFVDKRLAINIPKIKKFDSKLRNIYFTEADYTKHPFVAGIQDRVIRDFLKTHLSKDMDVCNDRFEYSPIGIKKTTFH
>CP026520.1|QAV18878.1|3241232_3241442_+|hypothetical-protein
MNDYTIGLVYSDKGCDIYFGLKTKVMNVLTAANLAGSRPYAKFYRTEDKMLLQLEYYRSEKPESSIFHV
>CP026520.1|QAV18879.1|3241768_3242548_+|hypothetical-protein
MDLKKINSITKYPSILTYHKLGERGKLTEEAVEERGYLTDSDKIFVYEKVDGENSRIIFFRNQFDEIDYLIGSREELLYAKGDRIGNPYGNIANFLKPMAERFVEDNFPSGDWALTVVYQESYGGKTKAAKNYTDSKTQSYKVFDVFSLTVNELENLLSLSSEKIAEWREHGNQPFYNEEERGKFVQANGLEWAPLLDEVYGSEFPVTLEETYRYLRNFEQTKVGIDAIGESEGIIARSADRKQIRKIRFEDYERTFRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NZ_CP042373	Lactobacillus malefermentans strain CBA3618 plasmid unnamed2, complete sequence	2046-2077	7	0.781
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NZ_CP050649	Enterococcus faecium strain BIOPOP-3 ALE plasmid pBIOPOP-3_ALE	26156-26187	7	0.781
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NZ_CP050651	Enterococcus faecium strain BIOPOP-3 WT plasmid pBIOPOP-3_WT	37180-37211	7	0.781
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NC_008499	Lactobacillus brevis ATCC 367 plasmid 2, complete sequence	34840-34871	7	0.781
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NZ_AP014681	Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-1, complete sequence	65521-65552	7	0.781
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NZ_CP013929	Alteromonas mediterranea strain UM8 plasmid pAMEDUM8_300, complete sequence	246563-246594	8	0.75
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	CP013931	Alteromonas mediterranea strain U10 plasmid pAMED10_300, complete sequence	251423-251454	8	0.75
CP026520_3	3.8\|3234338\|32\|CP026520\|CRT	3234338-3234369	32	NC_019394	Alteromonas mediterranea DE1 plasmid pAMDE1, complete sequence	246537-246568	8	0.75

1. spacer 3.8|3234338|32|CP026520|CRT matches to NZ_CP042373 (Lactobacillus malefermentans strain CBA3618 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

tccatttag--attcagaaaagtcttcatttgat	CRISPR spacer
--tatcaagtaattcaaaaaagtcttcttttgat	Protospacer
  .**. **  *****.********** ******

2. spacer 3.8|3234338|32|CP026520|CRT matches to NZ_CP050649 (Enterococcus faecium strain BIOPOP-3 ALE plasmid pBIOPOP-3_ALE) position: , mismatch: 7, identity: 0.781

tccatttag--attcagaaaagtcttcatttgat	CRISPR spacer
--tatcaagtaattcaaaaaagtcttcttttgat	Protospacer
  .**. **  *****.********** ******

3. spacer 3.8|3234338|32|CP026520|CRT matches to NZ_CP050651 (Enterococcus faecium strain BIOPOP-3 WT plasmid pBIOPOP-3_WT) position: , mismatch: 7, identity: 0.781

tccatttag--attcagaaaagtcttcatttgat	CRISPR spacer
--tatcaagtaattcaaaaaagtcttcttttgat	Protospacer
  .**. **  *****.********** ******

4. spacer 3.8|3234338|32|CP026520|CRT matches to NC_008499 (Lactobacillus brevis ATCC 367 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

tccatttag--attcagaaaagtcttcatttgat	CRISPR spacer
--tatcgagtaattcaaaaaagtcttcttttgat	Protospacer
  .**. **  *****.********** ******

5. spacer 3.8|3234338|32|CP026520|CRT matches to NZ_AP014681 (Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-1, complete sequence) position: , mismatch: 7, identity: 0.781

tccatttag--attcagaaaagtcttcatttgat	CRISPR spacer
--tatcaagtaattcaaaaaagtcttcttttgat	Protospacer
  .**. **  *****.********** ******

6. spacer 3.8|3234338|32|CP026520|CRT matches to NZ_CP013929 (Alteromonas mediterranea strain UM8 plasmid pAMEDUM8_300, complete sequence) position: , mismatch: 8, identity: 0.75

tccatttagattcagaaaagtcttcatttgat	CRISPR spacer
tttttttagattcagagaagccttcatctatt	Protospacer
*.. ************.***.******.*. *

7. spacer 3.8|3234338|32|CP026520|CRT matches to CP013931 (Alteromonas mediterranea strain U10 plasmid pAMED10_300, complete sequence) position: , mismatch: 8, identity: 0.75

tccatttagattcagaaaagtcttcatttgat	CRISPR spacer
tttttttagattcagagaagccttcatctatt	Protospacer
*.. ************.***.******.*. *

8. spacer 3.8|3234338|32|CP026520|CRT matches to NC_019394 (Alteromonas mediterranea DE1 plasmid pAMDE1, complete sequence) position: , mismatch: 8, identity: 0.75

tccatttagattcagaaaagtcttcatttgat	CRISPR spacer
tttttttagattcagagaagccttcatctatt	Protospacer
*.. ************.***.******.*. *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1247881 : 1255543

Salmonella_phage(14.29%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV17180.1\|1247881_1248898_-	glycosyltransferase	A8CG95	Salmonella_phage	2.9e-53	40.2
QAV17181.1\|1249154_1250654_+	catalase	A0A2K9L572	Tupanvirus	9.9e-119	53.4
QAV17182.1\|1251076_1252600_-	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	7.9e-31	36.7
QAV17183.1\|1252820_1253315_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	4.2e-50	65.8
QAV17184.1\|1253568_1254396_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	1.2e-49	43.6
QAV17185.1\|1254392_1254881_-	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	7.8e-57	68.6
QAV17186.1\|1254877_1255543_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	5.6e-66	56.1

DBSCAN-SWA_2

1747659 : 1754867

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV17607.1\|1747659_1748436_+	HTH domain-containing protein	U5J9C2	Bacillus_phage	5.1e-18	28.4
QAV17608.1\|1749726_1750479_+	hypothetical protein	A0A1P8CWY0	Bacillus_phage	4.7e-37	39.9
QAV17609.1\|1750488_1750713_+	hypothetical protein	NA	NA	NA	NA
QAV17610.1\|1750705_1750984_+	HU family DNA-binding protein	A0A0H3UZA0	Geobacillus_virus	7.1e-15	47.8
QAV17611.1\|1750995_1752204_+	hypothetical protein	A0A1P8CWS1	Bacillus_phage	9.5e-104	47.9
QAV17612.1\|1752355_1753243_+	hypothetical protein	Q331V7	Clostridium_botulinum_C_phage	6.7e-06	22.0
QAV21662.1\|1754105_1754867_+	hypothetical protein	A0A0H3V0N0	Geobacillus_virus	3.7e-21	31.1

DBSCAN-SWA_3

1763702 : 1842343

Geobacillus_virus(26.32%)

coat,integrase,tail,holin

attL 1758608:1758622|attR 1837729:1837743

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1758608:1758622	attL	NA	NA	NA	NA
QAV17625.1\|1763702_1769285_+\|tail	phage tail tape measure protein	A0A1P8CWQ1	Bacillus_phage	1.9e-66	37.6
QAV17626.1\|1769331_1770186_+	hypothetical protein	A0A0H3UZ48	Geobacillus_virus	2.0e-79	50.9
QAV17627.1\|1770197_1771376_+	hypothetical protein	A0A0H3UZC7	Geobacillus_virus	2.7e-127	54.2
QAV17628.1\|1771388_1772732_+	hypothetical protein	A0A0H3UZE0	Geobacillus_virus	3.1e-15	49.4
QAV17629.1\|1772750_1773758_+	hypothetical protein	A0A0H3UYV3	Geobacillus_virus	1.5e-83	44.6
QAV17630.1\|1773762_1774380_+	hypothetical protein	A0A0H3V0Q5	Geobacillus_virus	2.5e-20	44.7
QAV17631.1\|1774381_1774711_+	hypothetical protein	A0A0K1Y8A9	Streptomyces_phage	2.9e-07	38.0
QAV17632.1\|1776309_1776594_+	hypothetical protein	NA	NA	NA	NA
QAV17633.1\|1776607_1776745_+	XkdX family protein	NA	NA	NA	NA
QAV17634.1\|1776818_1777217_+\|holin	holin	D0R7H7	Paenibacillus_phage	3.2e-24	45.0
QAV17635.1\|1777228_1777945_+	peptidoglycan L-alanyl-D-glutamate endopeptidase	A0A127AWA8	Bacillus_phage	3.2e-43	60.0
QAV17636.1\|1777949_1778570_+	hypothetical protein	NA	NA	NA	NA
QAV17637.1\|1779555_1779768_+	hypothetical protein	NA	NA	NA	NA
QAV17638.1\|1779861_1780044_+	hypothetical protein	NA	NA	NA	NA
QAV17639.1\|1780130_1781243_+\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	3.6e-57	32.8
QAV17640.1\|1781284_1781509_+	DUF1805 domain-containing protein	NA	NA	NA	NA
QAV17641.1\|1781807_1783109_+	transcriptional regulator	NA	NA	NA	NA
QAV17642.1\|1783438_1783663_+	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
QAV17643.1\|1783675_1783876_+	hypothetical protein	NA	NA	NA	NA
QAV17644.1\|1784050_1785733_-	hypothetical protein	G1FGA4	Mycobacterium_phage	2.2e-10	49.5
QAV17645.1\|1786541_1787519_-	aldo/keto reductase	NA	NA	NA	NA
QAV17646.1\|1787766_1788255_+	hypothetical protein	NA	NA	NA	NA
QAV17647.1\|1789089_1789626_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
QAV17648.1\|1789701_1790499_+	inositol monophosphatase	NA	NA	NA	NA
QAV17649.1\|1790574_1791432_+	KR domain-containing protein	NA	NA	NA	NA
QAV17650.1\|1791777_1793874_+	PRD domain-containing protein	NA	NA	NA	NA
QAV17651.1\|1793900_1794344_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
QAV17652.1\|1794340_1794604_+	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
QAV17653.1\|1794624_1795920_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
QAV17654.1\|1796019_1797012_+	phosphotriesterase	NA	NA	NA	NA
QAV17655.1\|1797025_1797784_+	creatininase	NA	NA	NA	NA
QAV21663.1\|1797803_1798538_+	SIS domain-containing protein	NA	NA	NA	NA
QAV17656.1\|1798797_1799067_+	HPr family phosphocarrier protein	NA	NA	NA	NA
QAV17657.1\|1799066_1800824_+	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	7.8e-14	31.0
QAV17658.1\|1801305_1801926_-	flavin-nucleotide-binding protein	NA	NA	NA	NA
QAV17659.1\|1802218_1803214_+	gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
QAV17660.1\|1803487_1803769_-	hypothetical protein	NA	NA	NA	NA
QAV17661.1\|1803801_1804272_-	ester cyclase	NA	NA	NA	NA
QAV17662.1\|1804921_1805881_+	aldo/keto reductase	NA	NA	NA	NA
QAV17663.1\|1807889_1808573_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
QAV17664.1\|1809006_1810116_-	S-methyl-5-thioribose-1-phosphate isomerase	NA	NA	NA	NA
QAV17665.1\|1810115_1811342_-	S-methyl-5-thioribose kinase	NA	NA	NA	NA
QAV17666.1\|1811543_1811993_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	6.1e-48	67.2
QAV17667.1\|1812238_1812832_+	DUF1802 domain-containing protein	NA	NA	NA	NA
QAV17668.1\|1813172_1814009_+	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-07	25.9
QAV17669.1\|1814041_1815337_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
QAV17670.1\|1815333_1816560_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.9e-115	48.2
QAV17671.1\|1816546_1816975_+	SUF system NifU family Fe-S cluster assembly protein	A0A2H4N7M4	Lake_Baikal_phage	4.8e-10	32.1
QAV17672.1\|1817003_1818401_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
QAV17673.1\|1818640_1818955_+	hypothetical protein	NA	NA	NA	NA
QAV17674.1\|1819863_1820922_-	HD-GYP domain-containing protein	NA	NA	NA	NA
QAV17675.1\|1821186_1822401_-	thiamine biosynthesis protein ThiF	NA	NA	NA	NA
QAV17676.1\|1822621_1823386_-	molybdopterin converting factor	NA	NA	NA	NA
QAV17677.1\|1823542_1824994_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
QAV17678.1\|1825108_1825939_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
QAV21664.1\|1826165_1827218_+	HD-GYP domain-containing protein	NA	NA	NA	NA
QAV21665.1\|1827449_1829696_+	MMPL family transporter	NA	NA	NA	NA
QAV17679.1\|1829747_1830950_+	radical SAM/CxCxxxxC motif protein YfkAB	NA	NA	NA	NA
QAV17680.1\|1830977_1832327_+	HlyC/CorC family transporter	NA	NA	NA	NA
QAV17681.1\|1832344_1833391_+	sporulation integral membrane protein YtvI	NA	NA	NA	NA
QAV17682.1\|1833604_1836190_-	hypothetical protein	NA	NA	NA	NA
QAV17683.1\|1836396_1836600_+\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
QAV17684.1\|1836638_1836905_+\|coat	spore coat protein CotJB	NA	NA	NA	NA
QAV17685.1\|1836982_1837552_+\|coat	spore coat protein CotJC	NA	NA	NA	NA
QAV17686.1\|1837927_1838149_+	hypothetical protein	NA	NA	NA	NA
1837729:1837743	attR	NA	NA	NA	NA
QAV17687.1\|1838615_1839581_+	hypothetical protein	A0A024B138	Bacillus_phage	6.6e-15	49.6
QAV17688.1\|1839629_1840673_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
QAV17689.1\|1840961_1841816_+	cell wall lytic activity	A0A2I6UI13	Bacillus_phage	3.1e-08	35.0
QAV17690.1\|1841947_1842343_+\|holin	holin	D0R7H7	Paenibacillus_phage	4.0e-19	43.4

DBSCAN-SWA_4

2485806 : 2492932

Staphylococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV18255.1\|2485806_2486238_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	5.5e-22	45.5
QAV18256.1\|2486286_2486550_-	hypothetical protein	NA	NA	NA	NA
QAV18257.1\|2487660_2488800_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.2e-53	38.6
QAV18258.1\|2488784_2489453_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.5e-38	42.3
QAV18259.1\|2489492_2490716_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	4.9e-116	52.5
QAV18260.1\|2490782_2491253_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.6e-43	58.6
QAV18261.1\|2491350_2492133_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.7e-08	33.3
QAV18262.1\|2492101_2492932_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.5e-17	35.0

DBSCAN-SWA_5

2704553 : 2719706

Bacteriophage(84.62%)

tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV18456.1\|2704553_2705027_+	hypothetical protein	A0A0C5AN06	Bacteriophage	3.8e-32	43.4
QAV18457.1\|2705133_2706582_+\|tail	phage tail sheath family protein	A0A0C5AEE8	Bacteriophage	4.1e-194	68.5
QAV18458.1\|2706596_2707118_+\|tail	phage tail protein	A0A0C5AJ56	Bacteriophage	2.8e-76	83.0
QAV18459.1\|2707156_2707504_+\|tail	phage tail assembly protein	A0A0C5AEP1	Bacteriophage	9.5e-33	63.2
QAV18460.1\|2707665_2710074_+	hypothetical protein	M4ZR40	Bacillus_phage	2.4e-34	27.3
QAV18461.1\|2710081_2710291_+\|tail	phage tail protein	NA	NA	NA	NA
QAV18462.1\|2710287_2711319_+	late control protein	A0A0C5AJ59	Bacteriophage	1.0e-119	59.8
QAV18463.1\|2711320_2711737_+\|plate	phage baseplate assembly protein V	A0A0C5AEP6	Bacteriophage	2.6e-21	44.9
QAV18464.1\|2711733_2712123_+	hypothetical protein	A0A0C5AN08	Bacteriophage	4.0e-40	59.4
QAV21692.1\|2712143_2712452_+	lysozyme	A0A0C5ABJ8	Bacteriophage	3.8e-17	47.8
QAV21693.1\|2712583_2713576_+\|plate	baseplate J protein	A0A0C5AEG2	Bacteriophage	1.5e-115	62.3
QAV18465.1\|2713568_2714132_+\|tail	phage tail protein I	A0A0C5AJ63	Bacteriophage	1.9e-70	69.9
QAV18466.1\|2714131_2717599_+	hypothetical protein	A0A0C5AEQ0	Bacteriophage	7.7e-66	74.4
QAV18467.1\|2717595_2718120_+	hypothetical protein	NA	NA	NA	NA
QAV18468.1\|2718464_2718866_+	hypothetical protein	NA	NA	NA	NA
QAV18469.1\|2718935_2719706_+	N-acetylmuramoyl-L-alanine amidase	J9PV86	Bacillus_phage	5.4e-36	49.2

DBSCAN-SWA_6

3171963 : 3188181

Geobacillus_virus(50.0%)

tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV18801.1\|3171963_3172365_-\|holin	holin	D0R7H7	Paenibacillus_phage	1.1e-24	44.8
QAV18802.1\|3172445_3172586_-	XkdX family protein	NA	NA	NA	NA
QAV18803.1\|3172607_3172892_-	hypothetical protein	NA	NA	NA	NA
QAV18804.1\|3172908_3174489_-	hypothetical protein	NA	NA	NA	NA
QAV18805.1\|3174485_3174815_-	hypothetical protein	A0A0K1Y8A9	Streptomyces_phage	2.6e-08	40.7
QAV18806.1\|3174816_3175434_-	hypothetical protein	A0A0H3V0Q5	Geobacillus_virus	5.6e-20	46.3
QAV18807.1\|3175438_3176446_-	hypothetical protein	A0A0H3UYV3	Geobacillus_virus	1.5e-83	43.7
QAV18808.1\|3176464_3177808_-	hypothetical protein	A0A0H3UZE0	Geobacillus_virus	9.1e-15	48.2
QAV18809.1\|3177820_3178999_-	hypothetical protein	A0A0H3UZC7	Geobacillus_virus	6.3e-129	56.2
QAV18810.1\|3179010_3179865_-	hypothetical protein	A0A0H3UZ48	Geobacillus_virus	1.8e-77	49.5
QAV18811.1\|3179910_3186237_-\|tail	phage tail tape measure protein	A0A0K2FL55	Brevibacillus_phage	5.0e-87	34.1
QAV18812.1\|3186364_3186916_+	hypothetical protein	A0A0K2CP90	Brevibacillus_phage	6.4e-07	31.1
QAV18813.1\|3187197_3188181_-	hypothetical protein	U5JA40	Bacillus_phage	5.5e-102	57.7

DBSCAN-SWA_7

3273644 : 3288530

Bacillus_phage(45.45%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV18925.1\|3273644_3273917_+	hypothetical protein	A0A2R4ALD8	Vibrio_phage	7.0e-07	40.2
QAV21711.1\|3274447_3274630_+	hypothetical protein	NA	NA	NA	NA
QAV18926.1\|3274626_3275154_+	hypothetical protein	U5J9C6	Bacillus_phage	8.8e-30	37.6
QAV18927.1\|3275234_3276032_+	hypothetical protein	NA	NA	NA	NA
QAV18928.1\|3276054_3276294_+	hypothetical protein	NA	NA	NA	NA
QAV18929.1\|3276387_3276741_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	G3MBF1	Bacillus_virus	2.6e-30	58.4
QAV18930.1\|3276733_3278833_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	U5PY35	Bacillus_phage	2.4e-251	60.8
QAV18931.1\|3278858_3279836_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A0K2FLD5	Brevibacillus_phage	1.7e-98	57.5
QAV18932.1\|3279910_3280573_+	HNH endonuclease	A0A1P8CX39	Bacillus_phage	1.2e-36	55.6
QAV18933.1\|3280590_3281094_+	HAD family hydrolase	A0A0H3UZF4	Geobacillus_virus	1.0e-27	47.1
QAV18934.1\|3281160_3281973_+	thymidylate synthase	A6M9A2	Geobacillus_virus	8.3e-96	63.4
QAV18935.1\|3281974_3282193_+	hypothetical protein	NA	NA	NA	NA
QAV18936.1\|3282620_3283865_+	DNA polymerase IV	O64031	Bacillus_phage	8.6e-68	39.5
QAV18937.1\|3283861_3284206_+	YolD-like family protein	NA	NA	NA	NA
QAV18938.1\|3284207_3284654_+	Appr-1-p processing protein	A0A0H3V0V8	Geobacillus_virus	1.5e-38	53.0
QAV18939.1\|3285362_3288530_+	DNA polymerase III subunit alpha	A0A218KC91	Bacillus_phage	0.0e+00	54.2

DBSCAN-SWA_8

4752157 : 4799397

Paenibacillus_phage(18.18%)

tRNA,terminase,protease,integrase,portal,tail

attL 4784513:4784526|attR 4806303:4806316

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV20096.1\|4752157_4753558_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	1.7e-40	27.5
QAV20097.1\|4753634_4754186_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
QAV20098.1\|4754345_4755680_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
QAV20099.1\|4755716_4757813_-	type I DNA topoisomerase	A0A2K9L5F8	Tupanvirus	3.4e-109	39.7
QAV20100.1\|4758251_4758584_-	YolD-like family protein	NA	NA	NA	NA
QAV20101.1\|4758597_4758927_-	hypothetical protein	A0A2I7SCW2	Paenibacillus_phage	3.0e-12	51.4
QAV20102.1\|4758953_4759172_-	XRE family transcriptional regulator	A0A2K9V490	Faecalibacterium_phage	5.6e-07	43.8
QAV20103.1\|4759619_4759805_+	hypothetical protein	NA	NA	NA	NA
QAV21769.1\|4759933_4760107_+	XRE family transcriptional regulator	NA	NA	NA	NA
QAV20104.1\|4760353_4761043_-	peptidoglycan L-alanyl-D-glutamate endopeptidase	A0A127AWA8	Bacillus_phage	1.9e-45	59.7
QAV20105.1\|4761029_4761308_-	hypothetical protein	A0A0A7RW97	Clostridium_phage	6.1e-06	34.2
QAV21770.1\|4761324_4761600_-	hypothetical protein	NA	NA	NA	NA
QAV20106.1\|4761630_4761834_-	hypothetical protein	NA	NA	NA	NA
QAV20107.1\|4761893_4762580_-	hypothetical protein	NA	NA	NA	NA
QAV20108.1\|4762648_4763116_-	hypothetical protein	NA	NA	NA	NA
QAV20109.1\|4765801_4766263_-	hypothetical protein	A0A0C5AE97	Paenibacillus_phage	3.8e-05	44.4
QAV20110.1\|4766274_4769925_-	hypothetical protein	R4JDZ8	Bacillus_phage	2.0e-19	31.1
QAV20111.1\|4769939_4770737_-\|tail	phage tail family protein	A0A0U4B037	Exiguobacterium_phage	2.0e-09	27.5
QAV20112.1\|4770733_4775338_-\|tail	phage tail tape measure protein	NA	NA	NA	NA
QAV20113.1\|4775637_4775967_-	hypothetical protein	NA	NA	NA	NA
QAV20114.1\|4776023_4776809_-	hypothetical protein	NA	NA	NA	NA
QAV20115.1\|4777005_4777440_-	hypothetical protein	NA	NA	NA	NA
QAV20116.1\|4777444_4778026_-	hypothetical protein	NA	NA	NA	NA
QAV20117.1\|4778022_4778595_-	hypothetical protein	NA	NA	NA	NA
QAV20118.1\|4778603_4779194_-	hypothetical protein	NA	NA	NA	NA
QAV20119.1\|4779190_4779502_-	hypothetical protein	NA	NA	NA	NA
QAV20120.1\|4779572_4780571_-	hypothetical protein	NA	NA	NA	NA
QAV20121.1\|4780572_4781580_-	3-oxoacyl-ACP reductase	NA	NA	NA	NA
QAV20122.1\|4781687_4781882_-	hypothetical protein	NA	NA	NA	NA
QAV20123.1\|4781920_4783225_-\|portal	phage portal protein	NA	NA	NA	NA
QAV20124.1\|4783239_4784637_-\|terminase	terminase B	C9E2I7	Enterococcus_phage	2.9e-157	60.7
4784513:4784526	attL	NA	NA	NA	NA
QAV20125.1\|4784629_4785418_-\|terminase	terminase	A0A2H4J4R0	uncultured_Caudovirales_phage	7.9e-35	42.3
QAV20126.1\|4785664_4786252_-	hypothetical protein	H0USV4	Bacillus_phage	7.2e-41	49.5
QAV20127.1\|4786712_4787090_-	hypothetical protein	NA	NA	NA	NA
QAV20128.1\|4787829_4788132_-	hypothetical protein	NA	NA	NA	NA
QAV20129.1\|4788368_4788605_-	hypothetical protein	NA	NA	NA	NA
QAV20130.1\|4788638_4788821_-	hypothetical protein	NA	NA	NA	NA
QAV20131.1\|4788854_4789157_-	hypothetical protein	A0A0A8IL13	Aurantimonas_phage	8.9e-11	43.2
QAV20132.1\|4789182_4789803_-	hypothetical protein	A0A0K2CNK1	Brevibacillus_phage	3.5e-30	37.6
QAV20133.1\|4789836_4790091_-	hypothetical protein	NA	NA	NA	NA
QAV20134.1\|4790124_4790340_-	hypothetical protein	NA	NA	NA	NA
QAV20135.1\|4790368_4790587_-	hypothetical protein	A0A0K2CNV8	Brevibacillus_phage	7.3e-15	51.5
QAV20136.1\|4790645_4791269_-	hypothetical protein	A0A249XTI3	Mycobacterium_phage	6.1e-38	46.9
QAV20137.1\|4791278_4791524_-	DNA-entry nuclease	NA	NA	NA	NA
QAV20138.1\|4791564_4791855_-	hypothetical protein	NA	NA	NA	NA
QAV20139.1\|4792349_4792577_-	hypothetical protein	NA	NA	NA	NA
QAV20140.1\|4792569_4793166_-	HNH endonuclease	D0R7I8	Paenibacillus_phage	2.2e-37	48.0
QAV20141.1\|4793146_4793461_-	hypothetical protein	NA	NA	NA	NA
QAV20142.1\|4793565_4794384_-	hypothetical protein	A0A0K2CYY7	Paenibacillus_phage	3.8e-56	50.9
QAV20143.1\|4794274_4795294_-	hypothetical protein	S5M5Q5	Brevibacillus_phage	1.6e-35	48.5
QAV20144.1\|4795250_4795514_-	hypothetical protein	NA	NA	NA	NA
QAV20145.1\|4795790_4796057_-	hypothetical protein	NA	NA	NA	NA
QAV20146.1\|4796071_4796578_-	XRE family transcriptional regulator	NA	NA	NA	NA
QAV20147.1\|4796757_4796961_-	DNA-binding protein	NA	NA	NA	NA
QAV20148.1\|4796957_4797206_-	XRE family transcriptional regulator	NA	NA	NA	NA
QAV20149.1\|4797335_4797713_+	XRE family transcriptional regulator	A0A0A8WJ60	Clostridium_phage	1.5e-10	40.4
QAV21771.1\|4797790_4798306_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	7.8e-23	35.8
QAV20150.1\|4798272_4799397_+\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	1.1e-48	33.3
4806303:4806316	attR	NA	NA	NA	NA

DBSCAN-SWA_9

6007833 : 6018478

Prochlorococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAV21181.1\|6007833_6009378_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	Q58MG4	Prochlorococcus_phage	1.8e-70	49.2
QAV21182.1\|6009468_6010104_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.1e-26	38.5
QAV21183.1\|6010105_6011146_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.6e-73	46.8
QAV21817.1\|6011269_6012751_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-49	31.9
QAV21184.1\|6012735_6014979_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.9e-168	43.4
QAV21185.1\|6014956_6015652_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
QAV21186.1\|6015672_6015912_-	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	9.5e-08	37.7
QAV21187.1\|6016258_6017152_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	3.7e-36	32.9
QAV21188.1\|6017182_6018478_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	31.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026520

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection