CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	0 crisprs	NA	0	4	6
CP035458	Photobacterium damselae subsp. damselae strain KC-Na-NB1 chromosome 2, complete sequence	2 crisprs	cas3,DEDDh,cas14j,csa3,cas2,cas6f,cas7f,cas5f,cas8f,cas3f,cas1	5	7	3
CP035462	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-4, complete sequence	0 crisprs	NA	0	0	0
CP035457	Photobacterium damselae subsp. damselae strain KC-Na-NB1 chromosome 1, complete sequence	0 crisprs	DinG,RT,cas14j,csa3,cas3,DEDDh,csx1	0	0	3
CP035461	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence	0 crisprs	NA	0	0	0
CP035459	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence	0 crisprs	NA	0	0	0
CP035463	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-5, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1949267 : 2020051

Escherichia_phage(25.0%)

tRNA,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY35516.1\|1949267_1949858_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
QAY35517.1\|1950175_1951123_-	ribose-phosphate pyrophosphokinase	A0A2K9L8D8	Tupanvirus	7.1e-46	38.1
QAY35518.1\|1951155_1952025_-	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
QAY35519.1\|1952039_1952693_-	outer membrane lipoprotein LolB	NA	NA	NA	NA
QAY35520.1\|1952953_1954207_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
QAY35521.1\|1954376_1955465_+	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	2.3e-08	40.3
QAY35522.1\|1955466_1956315_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
QAY35523.1\|1956327_1956708_+	invasion protein	NA	NA	NA	NA
QAY35524.1\|1956749_1957559_+	tetratricopeptide repeat protein	NA	NA	NA	NA
QAY35525.1\|1957573_1958428_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	2.4e-45	40.1
QAY35526.1\|1958719_1959979_+	HAAAP family serine/threonine permease	NA	NA	NA	NA
QAY35527.1\|1960075_1961959_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.0e-21	52.5
QAY35528.1\|1962261_1963620_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
QAY35529.1\|1963904_1965572_+	bifunctional UDP-sugar hydrolase/5'-nucleotidase	NA	NA	NA	NA
QAY35530.1\|1965714_1966194_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
QAY35531.1\|1966393_1966744_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.8e-16	46.3
QAY35532.1\|1966777_1967920_+\|transposase	transposase	A0A077SLN2	Escherichia_phage	8.3e-134	70.4
QAY35533.1\|1969981_1970563_+	DNA endonuclease SmrA	NA	NA	NA	NA
QAY35534.1\|1970750_1971584_-	TraB/GumN family protein	NA	NA	NA	NA
QAY35535.1\|1971792_1974702_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	8.7e-103	35.7
QAY35536.1\|1974882_1975278_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
QAY35537.1\|1975274_1975712_-	hypothetical protein	NA	NA	NA	NA
QAY35538.1\|1975698_1976364_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
QAY35539.1\|1977036_1978068_+	OmpA family protein	NA	NA	NA	NA
QAY35540.1\|1978255_1978669_+	META domain-containing protein	NA	NA	NA	NA
QAY35541.1\|1978736_1979591_-	co-chaperone YbbN	NA	NA	NA	NA
QAY35542.1\|1979864_1980689_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
QAY36525.1\|1980705_1981614_-	TIGR01777 family protein	NA	NA	NA	NA
QAY35543.1\|1981743_1982292_+	phosphodiesterase	NA	NA	NA	NA
QAY35544.1\|1982391_1984539_-	phosphate acetyltransferase	NA	NA	NA	NA
QAY35545.1\|1984699_1985896_-	acetate kinase	NA	NA	NA	NA
QAY35546.1\|1986235_1986685_+	DUF412 domain-containing protein	NA	NA	NA	NA
QAY35547.1\|1986900_1987839_-	hypothetical protein	NA	NA	NA	NA
QAY35548.1\|1987954_1988785_-	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
QAY36526.1\|1988962_1989076_+	DUF2057 domain-containing protein	NA	NA	NA	NA
QAY35549.1\|1989124_1990402_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
QAY35550.1\|1990388_1992758_-	HAMP domain-containing protein	NA	NA	NA	NA
QAY35551.1\|1992761_1994003_-	extracellular solute-binding protein	NA	NA	NA	NA
QAY35552.1\|1994216_1994717_-	YfbU family protein	NA	NA	NA	NA
QAY35553.1\|1995009_1996764_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
QAY35554.1\|1997377_1998124_-	pyruvate formate lyase 1-activating protein	A0A2P0VNQ0	Tetraselmis_virus	3.4e-27	31.0
QAY36527.1\|1998238_1998373_-	hypothetical protein	NA	NA	NA	NA
QAY35555.1\|1998433_2000329_+	U32 family peptidase	Q6DW11	Phage_TP	3.1e-24	26.5
QAY35556.1\|2000604_2002878_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	2.3e-159	41.5
QAY35557.1\|2002934_2003807_-	formate transporter FocA	NA	NA	NA	NA
QAY35558.1\|2004631_2006380_-	30S ribosomal protein S12 methylthiotransferase accessory protein YcaO	NA	NA	NA	NA
QAY35559.1\|2006462_2007278_-	exodeoxyribonuclease III	A0A0N9QXX6	Chrysochromulina_ericina_virus	1.3e-16	26.7
QAY35560.1\|2007740_2007989_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
QAY36528.1\|2008117_2008561_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	5.5e-25	49.6
QAY35561.1\|2008603_2009746_+\|transposase	transposase	A0A077SLN2	Escherichia_phage	3.2e-133	70.4
QAY35562.1\|2009912_2010572_-	hypothetical protein	NA	NA	NA	NA
QAY35563.1\|2010667_2011711_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.5e-73	42.6
QAY35564.1\|2011697_2012456_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-75	62.0
QAY35565.1\|2012501_2012768_-	hypothetical protein	NA	NA	NA	NA
QAY35566.1\|2014082_2015192_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
QAY35567.1\|2015191_2018299_+	efflux RND transporter permease subunit	NA	NA	NA	NA
QAY35568.1\|2018842_2020051_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	7.9e-50	47.6

DBSCAN-SWA_2

2064140 : 2074011

Enterobacteria_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY35606.1\|2064140_2065925_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.5e-28	42.5
QAY35607.1\|2065966_2067028_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-99	52.2
QAY35608.1\|2067107_2067980_+	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	3.2e-109	67.2
QAY35609.1\|2067992_2068883_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.8e-36	35.4
QAY35610.1\|2068900_2069446_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	5.8e-53	56.7
QAY35611.1\|2069447_2070230_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
QAY35612.1\|2070226_2071117_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.8e-59	46.4
QAY35613.1\|2071237_2072446_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	7.9e-50	47.6
QAY35614.1\|2072518_2073388_-	hypothetical protein	NA	NA	NA	NA
QAY35615.1\|2073384_2074011_-	N-acetylmuramoyl-L-alanine amidase	A0A0S2MWH1	Cellulophaga_phage	8.3e-27	36.0

DBSCAN-SWA_3

2699407 : 2758208

Escherichia_phage(50.0%)

lysis,transposase,integrase

attL 2734041:2734100|attR 2758588:2760534

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY36089.1\|2699407_2700700_+\|integrase	site-specific integrase	NA	NA	NA	NA
QAY36090.1\|2700692_2702630_+	hypothetical protein	NA	NA	NA	NA
QAY36091.1\|2702640_2704629_+	hypothetical protein	NA	NA	NA	NA
QAY36092.1\|2704634_2705021_+	hypothetical protein	NA	NA	NA	NA
QAY36093.1\|2705034_2705877_+	hypothetical protein	NA	NA	NA	NA
QAY36094.1\|2706673_2707717_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.5e-73	42.6
QAY36095.1\|2707703_2708462_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-75	62.0
QAY36096.1\|2708940_2710692_+	restriction endonuclease subunit S	NA	NA	NA	NA
QAY36097.1\|2710694_2711930_+	DUF262 domain-containing protein	NA	NA	NA	NA
QAY36098.1\|2711974_2713891_+	DUF262 domain-containing protein	NA	NA	NA	NA
QAY36099.1\|2713946_2714540_+	hypothetical protein	NA	NA	NA	NA
QAY36100.1\|2714664_2715876_-	protein kinase	NA	NA	NA	NA
QAY36101.1\|2716033_2716489_-	TerB family tellurite resistance protein	NA	NA	NA	NA
QAY36102.1\|2716570_2717536_-	zinc transporter ZntB	NA	NA	NA	NA
QAY36103.1\|2717875_2721790_+	ATP-dependent RNA helicase HrpA	A0A1V0SIV3	Klosneuvirus	1.2e-54	29.8
QAY36104.1\|2721901_2722567_-	peptidase M23	NA	NA	NA	NA
QAY36105.1\|2722556_2723798_-	MFS transporter	NA	NA	NA	NA
QAY36106.1\|2724806_2726360_+	BCCT family transporter	NA	NA	NA	NA
QAY36107.1\|2726475_2727708_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
QAY36108.1\|2727826_2728297_-	hypothetical protein	NA	NA	NA	NA
QAY36109.1\|2728501_2728858_-	glutaredoxin	NA	NA	NA	NA
QAY36110.1\|2729031_2729376_+	DUF3802 family protein	NA	NA	NA	NA
QAY36111.1\|2729488_2730211_+	DTW domain-containing protein	NA	NA	NA	NA
QAY36112.1\|2730339_2731251_+	N-acetylglucosamine kinase	NA	NA	NA	NA
QAY36113.1\|2731478_2732765_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.5e-46	32.6
2734041:2734100	attL	NA	NA	NA	NA
QAY36114.1\|2734109_2734868_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-75	62.0
QAY36115.1\|2734854_2735898_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.5e-73	42.6
QAY36116.1\|2735956_2737339_-	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
QAY36117.1\|2737820_2738495_-	SanA protein	NA	NA	NA	NA
QAY36118.1\|2738737_2740426_-	NAD-dependent malic enzyme	NA	NA	NA	NA
QAY36119.1\|2740866_2741763_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
QAY36120.1\|2741966_2744423_+	ATP-dependent RNA helicase	A0A2H4UU36	Bodo_saltans_virus	1.8e-29	28.6
QAY36121.1\|2744451_2744820_+	spore gernimation protein	NA	NA	NA	NA
QAY36122.1\|2744992_2745421_-	nitrous oxide-stimulated promoter family protein	NA	NA	NA	NA
QAY36123.1\|2745659_2745953_+	hypothetical protein	NA	NA	NA	NA
QAY36124.1\|2746265_2746904_+	thiopurine S-methyltransferase	NA	NA	NA	NA
QAY36125.1\|2747003_2748179_-	formate-dependent phosphoribosylglycinamide formyltransferase	NA	NA	NA	NA
QAY36126.1\|2748352_2749225_-	DMT family transporter	NA	NA	NA	NA
QAY36127.1\|2749412_2750300_-	cytidine deaminase	NA	NA	NA	NA
QAY36128.1\|2750494_2751175_-\|lysis	CidB/LrgB family autolysis modulator	NA	NA	NA	NA
QAY36129.1\|2751171_2751516_-	hypothetical protein	NA	NA	NA	NA
QAY36130.1\|2751689_2752205_-	hypothetical protein	NA	NA	NA	NA
QAY36131.1\|2752346_2753768_-	exodeoxyribonuclease I	NA	NA	NA	NA
QAY36132.1\|2755302_2755569_-	hypothetical protein	NA	NA	NA	NA
QAY36133.1\|2755579_2756593_-\|transposase	IS630 family transposase	NA	NA	NA	NA
QAY36134.1\|2756981_2758208_+\|integrase	site-specific integrase	A0A067ZJC5	Vibrio_phage	6.1e-58	36.3
2758588:2760534	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP035461

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP035458

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP035458_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035458_1

863876-864025

TypeI-F

I-F

Consensus_repeat	Method
ATTTCTAAGCTGCCTACTCGGCAGTGAAG	CRISPRCasFinder
TGTAGATTTCTAAGCTGCCTACTCGGCAGTGAAGG	PILER-CR

2 spacers

cas6f,cas7f,cas5f,cas8f,cas3f,cas1

The CRISPR arrays of CP035458_1

>merge|CP035458|1|863876-864025|CRISPRCasFinder,PILER-CR
TTAGTATGGCTGCCTACTCGGCAGTGAAGGCACTTGGCGGCTGTGTTTTAAATGCTTTATATTTCTAAGCTGCCTACTCGGCAGTGAAGGAGAAAGGAACATCAGAGTGCGCAGATGTAGATTTCTAAGCTGCCTACTCGGCAGTGAAGT

>CP035458|1|1|863876-864024|CRISPRCasFinder
TTAGTATGGCTGCCTACTCGGCAGTGAAG	GCACTTGGCGGCTGTGTTTTAAATGCTTTAT
ATTTCTAAGCTGCCTACTCGGCAGTGAAG	GAGAAAGGAACATCAGAGTGCGCAGATGTAG
ATTTCTAAGCTGCCTACTCGGCAGTGAAG

>CP035458|1|1|863884-864025|PILER-CR
GCTGCCTACTCGGCAGTGAAGGCACTTGGCGGCTG	TGTTTTAAATGCTTTATATTTCTAA
GCTGCCTACTCGGCAGTGAAGGAGAAAGGAACATC	AGAGTGCGCAGATGTAGATTTCTAA
GCTGCCTACTCGGCAGTGAAGT

Protein	Signature genes	Signature genes Name	Protein_function
CP035458.1\|QAY37230.1\|865714_866713_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	pfam09614_cas5f_CAS-I-F	gnl\|CDD\|378221
CP035458.1\|QAY37234.1\|872593_873637_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
CP035458.1\|QAY37232.1\|867987_871320_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|274201
CP035458.1\|QAY37233.1\|871316_872291_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
CP035458.1\|QAY37227.1\|863376_863790_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
CP035458.1\|QAY37222.1\|854640_857340_+\|bifunctional-acyl-CoA-synthetase/GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223972
CP035458.1\|QAY37219.1\|852511_853066_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP035458.1\|QAY37224.1\|858301_861580_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378703
CP035458.1\|QAY37235.1\|873623_874382_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
CP035458.1\|QAY37221.1\|854009_854519_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227700
CP035458.1\|QAY37229.1\|864717_865707_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
CP035458.1\|QAY37228.1\|864161_864716_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl\|CDD\|378224
CP035458.1\|QAY37220.1\|853242_853830_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225805
CP035458.1\|QAY37461.1\|861661_861871_+\|YnbE-family-lipoprotein	unknown	unknown	gnl\|CDD\|379294
CP035458.1\|QAY37223.1\|857704_858034_+\|hypothetical-protein	unknown	unknown	unknown
CP035458.1\|QAY37226.1\|862373_863324_+\|putative-sulfate-exporter-family-transporter	unknown	unknown	gnl\|CDD\|225411
CP035458.1\|QAY37225.1\|861888_862212_+\|DUF1318-domain-containing-protein	unknown	unknown	gnl\|CDD\|377762
CP035458.1\|QAY37231.1\|866670_867972_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	pfam09611_cas8f_CAS-I-F	gnl\|CDD\|187866
CP035458.1\|QAY37236.1\|875140_875311_-\|ClbS/DfsB-family-four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|377957
CP035458.1\|QAY37237.1\|875494_875974_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|182339

Protein	Function_ID	Function_description	E-value
CP035458.1\|QAY37230.1\|865714_866713_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	9.8005e-114
CP035458.1\|QAY37234.1\|872593_873637_+\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.26107e-45
CP035458.1\|QAY37232.1\|867987_871320_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|274201	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST. The helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.	0
CP035458.1\|QAY37233.1\|871316_872291_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	0
CP035458.1\|QAY37227.1\|863376_863790_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	9.93149e-72
CP035458.1\|QAY37222.1\|854640_857340_+\|bifunctional-acyl-CoA-synthetase/GNAT-family-N-acetyltransferase	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	0
CP035458.1\|QAY37219.1\|852511_853066_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	9.21569e-78
CP035458.1\|QAY37224.1\|858301_861580_+\|hypothetical-protein	gnl\|CDD\|378703	pfam11739, DctA-YdbH, Dicarboxylate transport. In certain bacterial families this protein is expressed from the ydbH gene, and there is a suggestion that this is a form of DctA or dicarboxylate transport protein. Dicarboxylate transport proteins are found in aerobic bacteria which grow on succinate or other C4-dicarboxylates.	1.26615e-40
CP035458.1\|QAY37235.1\|873623_874382_+\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	1.25041e-146
CP035458.1\|QAY37221.1\|854009_854519_+\|hypothetical-protein	gnl\|CDD\|227700	COG5413, COG5413, Uncharacterized integral membrane protein [Function unknown].	5.26985e-31
CP035458.1\|QAY37229.1\|864717_865707_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
CP035458.1\|QAY37228.1\|864161_864716_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	6.13415e-74
CP035458.1\|QAY37220.1\|853242_853830_-\|hypothetical-protein	gnl\|CDD\|225805	COG3266, DamX, Uncharacterized protein conserved in bacteria [Function unknown].	3.25159e-13
CP035458.1\|QAY37461.1\|861661_861871_+\|YnbE-family-lipoprotein	gnl\|CDD\|379294	pfam13617, Lipoprotein_19, YnbE-like lipoprotein. This family includes lipoproteins similar to E. coli YnbE. Protein in this family are typically 60 amino acids in length and contain an N-terminal lipid attachment site, which has been included in the alignment to increase sensitivity. The specific function of these proteins is unknown.	1.14306e-10
CP035458.1\|QAY37226.1\|862373_863324_+\|putative-sulfate-exporter-family-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	7.35928e-52
CP035458.1\|QAY37225.1\|861888_862212_+\|DUF1318-domain-containing-protein	gnl\|CDD\|377762	pfam07027, DUF1318, Protein of unknown function (DUF1318). This family consists of several bacterial proteins of around 100 residues in length and is often known as YdbL. The function of this family is unknown.	2.05577e-32
CP035458.1\|QAY37231.1\|866670_867972_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|187866	cd09735, Csy1_I-F, CRISPR/Cas system-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins; Predicted subunit of the Cascade complex; signature gene for I-F subtype; also known as Csy1 family.	1.43888e-113
CP035458.1\|QAY37236.1\|875140_875311_-\|ClbS/DfsB-family-four-helix-bundle-protein	gnl\|CDD\|377957	pfam08020, DUF1706, Protein of unknown function (DUF1706). This family contains many hypothetical proteins from bacteria and yeast.	4.3899e-06
CP035458.1\|QAY37237.1\|875494_875974_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	6.61408e-64

>CP035458.1|QAY37227.1|863376_863790_-|aminoacyl-tRNA-hydrolase
MLTISNNVTISDWEIELNAIRSAGNGGQNVNKVATAIHLRFDIKKSSLPAIYKEKLLKLSDSRISSDGVIIIKSQQYRTQLQNKEAALERLKELILSAMVVQKARRPTKPTKSSQRRRLESKTKRGSTKTMRKKVDY
>CP035458.1|QAY37226.1|862373_863324_+|putative-sulfate-exporter-family-transporter
MLFKKIFARLQPSDALFFIAAFFCLLPFVSSPIALILGFSLASLGLVPTQFNIAAATKKLLSYSIIGLGFGIHLNEAIEASKQGLGLIVCSIFFTLILGWVVTRLMGLDKKTGHLIASGTAICGGSAIAAVAPAINAKDDEISLALATVFVLNAIALFIFPVIGHLLDMSQHAFGTWAAIAIHDTSSVVGAAGSYGDEALKTATTLKLARALWIIPVAFISALLFKGNSKKISVPFFIVFYCLAIVFAHFVPSLQPAYNMIFAFSKRLLVMCLFLIGSGITINKLRNAGAKPLLLGVILWLAIGGASLAYIEATMA
>CP035458.1|QAY37225.1|861888_862212_+|DUF1318-domain-containing-protein
MKRITLFLCALLFSVNAFAISLQQAKSQGLVGEANNGYIAIVTGSPSAEVKRLVQQVNQQRKSKYQSIGSSHGLSVNEVARLAYKKAVSKTPRGQYYQSTTGQWVKK
>CP035458.1|QAY37461.1|861661_861871_+|YnbE-family-lipoprotein
MQQSVVIHKLTVLGAAVLITFALIGCTPTVQVATSNKPIEVNLNVKIEHEIRIKVDKEIDNLFKDEAVF
>CP035458.1|QAY37224.1|858301_861580_+|hypothetical-protein
MPLDSYPKKIPTSSNSSPDQATNHTLNHKKKWLRRLGFLLAALLGLSLVSVYTLLKLLAQHEVQIHRISGIQLFSAPHIEKLAVVYQGVPIEMNHISINTSPLTIKIQQVQSQIPKKDQEPLQPYQFRSLHLAQLEMHSPSWRLDQMFTVTINKATVSLTINQEPTHIYQQQIHQLHIEIDPNNDSYSDNNYLNNSYAIATKIHDIDVTVPVQTKVEDQPDVEIIQYRANLKQLSAKLQIAKKNPMQQPIPLSVAIDAIKPSWQSLEEIEQTIQNIHIDTDLTHWKSNTTIKINQAHLIQPQYLPLDIKKSDSEYQGFHIGQAIANLAQLPVNFSINQLTYLPLIYNAEVFLQQPSLDNLVTDQEQPQRPHFYFSGHVLSQQPYKMDLSLFYQDLKNMTVTAGLVGKKGNSVFCDSVISADLPLPKRLDCQLNLKQTKDITDNWQIIDAPNAILNKPITLQARQINHLIPNEVKNDDIKSAHYHVDLKLPQKINIQLPKAWSWDLLNIPRQVQVTNDGKLSIELRYAEKFLQLSLRGKQESLGVSIQNKKQHIVKTNIDINKLKCFPSKLQCHGNGVISNHLSSLLFSSLPQQIDTSSPLILQTKSHWQLTYKDQQFIGQLTDNQLSLSSFRLQQPSYSLKLSNNQLVVPQWVILANTHQWQLYAPKVKDITFTSNAEATVAIETNSQASHPVQKITSPLKMTMGSFWVDKQSKQSIKIKSHIHSQLSPILNGQTLPKLDLNTQLQLAKGEISLENRIHSLLPNQQSVPLADIKIRHNLNQQSGLLDVRLSPWQFDSKRRLSQYYLPEIPTGIELVSGKLEGHLVTRYRQFQPISSQVSLYTKELSGMFFNIPFHNANIQLELQQDQQGIQTRSPTIVDIEKIKLGIPLTNIRLSGHYQDYAYKLNHGYIELLDGFITTTPTQSRQPWQQLSLPISIHGINLATLMSQIDQQDIELTGILDGKLTLALHKGLFDIHNGKLIARYPGGLFRYKQGSTIDNRVEAMDDSNPIVVSKLLKNYHYRTLVVDIDYSNKGILKAKSQFKGYNPDFQNGRPIHLNLNIEDNVPALIKTLSLLNSSDVERYLQEQFGKQE
>CP035458.1|QAY37223.1|857704_858034_+|hypothetical-protein
MKSAPHSLNQTIQALKSVTTQMMAAESLTGEVMSAHMIQQITAIERTELEIASQQIMVIEKALTQALVALEREDLVATREAIFNALYELNHQSPAISKLMYENDPVLAG
>CP035458.1|QAY37222.1|854640_857340_+|bifunctional-acyl-CoA-synthetase/GNAT-family-N-acetyltransferase
MATTPLSALLNPKSIAVIGASNQTHRTGFVIINNLLQSHFNGPIFPVTPKYDSVAGILAYPTISDLPRTPDIAIVCTHASKTVKIIKELGEKGVKSAVILAAGTSTLKDETGTTVADYLQQLAKRYQIRLLGPNSMGIILPWLNLNASFAPTPANKGNIAFISQSAAVCTTILDWARNKNIGFSTFISLGDGLDINFAELLDALSRDGKTEAILLYLDSVNNAREFLSAARAAARNRRILVVKGGRILAGSEAVKQHTGSNLGADIVYEAAIRRAGLLRVKNTYELFAAVETLAHSVPLRGERLAIITNGGGPAIMAVDSLSERGGKLAQLSSTTLHQLKKQLPNYWPASNPIDLLGDATIERYEHAINTLLDSDEADALLIMHTPSAIAPSQQTAERLVQILKQHPNIKKFNVLSNWTGEYEGQVARDIFAQAGFPAYRTPESAVSAFMYLVEYRRNQKLLRETPKTLEPIATSNKNFSPQQAQAIIQELLNHNITQLETHEVQPILKGYGFKTLPTWLANNAVEAIHIAEQIGYPVAVKLRSPDIEHKSEVHGVMLHLRDAQEVESAAQAMLERVNIDYPTAQIDGLLVQRMANRAGAQELRVAVRNDPIFGPVIFLGEELMNWNCYQDSAVGLPPLNMALARYMIIDALKSHKIKQRSTLVPIDIDALCSLLVTVSQLVIDCPNIESLDIHPLLANGPELTIIDASMTLNTDSNQIPRLAIRPYPKELEQWVELKSGKTILLRPILPEDEPEHKSFISHVTQEDLYKRFFSDVGEFNHEAMSNFTQIDYDREMAFIAVFENKGHTEILGVVRALSDPDNVDAEFAILIRSDLKGLGLGRIMMEKIIHYCQHKGLQRITGMTMPNNRSMIMLAQKMGFHVDIQMEDGVVEMELNLTK
>CP035458.1|QAY37221.1|854009_854519_+|hypothetical-protein
MADPHIQCELDGLDKLTVLLYRSSLTFAAGVMSIIAWEFNFGTVAIIIAALLASTTVHIYDKRFRWLIQGAGLFASVWYMTGLWSPLAQGAALFVFSALAVKEYFCFQLKVLLVTPLALAGFWFCQVFGQAQISILFSMASAILLAVAAFSKWRMPLHFDIGDKSRYQI
>CP035458.1|QAY37220.1|853242_853830_-|hypothetical-protein
MKKIALAILASLLAGCVTSPQHSAPVQAVNIPPTPEVKPQPQTVVVEPAQFSADGLGFNEESLTGKSVEVPNHVKEVIKLSPSVAEPEVKPASKPTYQYSDLNKSAYAIQLVASGSKDQLSSYAKQLPKGEALWISKTDRNGQPWYALLYGQYDSRDAAHEAILALPLTVQQNGAFIKNLRSLKESENTQVSSFN
>CP035458.1|QAY37219.1|852511_853066_-|sugar-O-acetyltransferase
MKTEFEKMISGEIYNGMDPEIDTLRTEVEKQLIPLNQTTIREQRPLLESLLGKFGSDSVIRMPFSCEYGKNIFIGDQTFVNAGAVWLDNAPITIGSHVLIGPNSQFFTPTHSLDYRSRRNWETWCLPITIEDDVWIGGNVCICQGVTIGARSVVAAGSVVTSDVPPDTLVGGTPAKVIKALNND
>CP035458.1|QAY37228.1|864161_864716_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDYYLDIQVEPDLEITAPALLNNLFAKFHRAMSQCCIGRIAVSFPSYNKSLGETLRLHGTQADLDELMALPWLKGLRDYTKVSAILPIPRDIAGHRTVHRVQKKSPHNLRKRAVAKGRMTEQEALTKIPDALQERLALPFIQMQSLSNKQVMRIYVALGEIQSEPVLGEFSSYGMSRTSTIPWF
>CP035458.1|QAY37229.1|864717_865707_-|type-I-F-CRISPR-associated-protein-Csy3
MTMSKLETPSVLAFEAKLACSDAIMFAGNWEERDTVASWAPILVTEKSVRGTISNRLKGAKASKIDAEVEKANLQTVDNAALNFDTDTLKVTFSLRVLGNLGVPSTCNNPDYQQALASKITTYVQEEGFTELATRYALNLANGRFLWRNRVGAEQVEVRISHQEQTWCFDALNYSLRDFDERDQDIKAIATVIEQGLMGEKPTLLTVEAFVQLGEGQTVFPSQELVMNTGDKKSKYLYQLSGQAAMHSQKIGNALRTIDTWYPAAGECGPIAIEPYGSVTNRGIAYRKPKEKTDFYTLLDGWMLKDKQPTTCELHYMMAMLIRGGVFGE
>CP035458.1|QAY37230.1|865714_866713_-|type-I-F-CRISPR-associated-protein-Csy2
MAKTVLKCITGDRIMEQYLVLKQIDVTNANAISGFTYGFPAITHFLGYVHALSRKLTHRGITLSDVAVVCHQHQTHAYRESSYEPYSFALTRNPLTKEGKTAPINEEGRMSMTVSLIIKASGIPNHVDSEKQATCELIKQLAEQQKLAGGRIVSIRSCQLAKDNATAKTLLRGLLPGFVLVDRSDLMAINEQNQETVSHWLSFSALKYQSVELKKYDESQDRNESYIEWQRIAKPAGYLVPIQIGYKAISPLYEAGTVANVRDIETSVSFVEAVHSIGEWVGAPSRISSMDQILWRYHYHAPFYVAHSQQQSMNGDLMPISPDNKIEYNEDY
>CP035458.1|QAY37231.1|866670_867972_-|type-I-F-CRISPR-associated-protein-Csy1
MPETLAQNIKTFIAERYQTKLEEKQKAYDKNKAAAVTAEDFDRIESQFLADKEKLLQQFELNAWIDNAARRANQISMATHALKFTNSSAKGSNVLAYDLSHDARYLDTEIIQEKAIDAVGNAAALDVARFLQLTDENGLSLLSYLAKADHRPLALIAKSDEELIHWLDGLKQALRDTSPSSHVLGKQIYFPVSDNEYHLLAPLYSSSLAQVLFDAVQYSRFSQEMKAIREAKRHNDFHPQPLIAYPNLAVTVSGGSKPQNVSQLNNKRSGKTYLFSAAPPNWQAQNKPPLGLDSILRHRDIYYHTQEPITRLTQFLIKLNAASTESNMRIRHYIVNTVDEVIDQILLVAAKWQQLPAGWSDKSDLPLAQRRWLDPNNSQWDRFDDHWQQAIAENVGLWLKDKVNKGSQNHFTLGQIEAMEWQKQCLNALQEIA
>CP035458.1|QAY37232.1|867987_871320_-|type-I-F-CRISPR-associated-helicase-Cas3
MNILLISECNKQALPETRRILDQFAERKGSRTWQTPITFEGLKTLRMLLKKTARRNTAVACYWIHGKNQTELLWIVGNRRKFNEQGTVPTNITERDILRTQDENGMNSIQSVALLAALAGLFHDFGKANQLFQNKLKPKSKVRFEPYRHEWISLWLFVAFVNQRCDSEWLDDLAQSRLPNDTELLAQLDPERTFIIEDLLPIAQCVAWLIVSHHRLPKYLLGNVNIDVWRQGMDAAWNALNHKSETLGEKEFKQNIQFPFGTPFASATWRHKAKEIAKRANQLPNFTEYAQLEKAFPLHLARMALMLADHTYSADVAHENWQDLNYQANANTDRKTGKIKQKLDEHCIGVAHNAYILARTLPRLRSVMPAITQHKGFKRRCKNAKFRWQDKAYDCAYAIAELSEQNGFFGVNMASTGKGKTFANARIMYGLSNPKLGCRFSVALGLRTLTLQTGDALQQRLCLDSDDVAVHIGSQAVHDLFYRDKKAQQAALDNHEAAVRTGSESELLFSEHNYVRYDGEVDNHYLQRWLKEKGAIHKLVSAPISVSTIDHLMPVSEGITGGQQIAPMMRLLTSDLVLDEPDDFSLDDDPALGRLVYFAGLLGSRVLLSSATLPPALVNHLFACYQAGRAQYNQVTGQQHQKPVCCAWFDEFGVQSNQADGIAQFNQYHQMFTQSRKQALDKYQQPLHVGNWLNIDEKASPDQSVIELFTRTLYQGIYQLAAEHHTQSTQPNSNGKTVSAGIIRMANIEPLVAVANSLFSLPAKENTRIHYCVYHSQHPLAVRSAIENQLDQLLQRDRVDLQDIVTKPTVERVLIQYSEQHHIFVVLATPVAEVGRDHDYDWAIVEPSSMRSIIQLAGRVQRHRQLVPNGANILVLNKNIKALKQSSVAYTSPGFESDKLYYRIDGHRFPYLQLTDHDLRNQLHLRTLKNISSEPRFICPKPLVDEVQQRVIGFIELEHQATLFYMQQYLKPWWQSHCAHLIGELQKQTPFRQSRPSVNYIMMLDDDSDYITLQVWDNASQSWIDSGLLTPFSERELASGISLWGSGCLTDEIEQLAEEYQLEISTTCERFAAINLPENSASDCGKPWLYDPILGVFRGRDITPLNHDSV
>CP035458.1|QAY37233.1|871316_872291_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MKKDFSPSELKTILHSKRANLYYLQHCRVLVNSGRVEYVTDEGKESLYWNIPIANTTAIMLGTGTSVTQAAMRELAKAGVLVGFCGGGGTPLFSGNEVQVDVSWLLPQSEYRPTEYLQQWVSFWFDDNARLTAAKAFQHQRIKQIHKQWQRLENKHDFAYNAELLDGALQRFSDNIETCQTSQDLLLLEATTTKTLYKIACHAVQYGEFTRSERGNSTDIANRFLDHGNYLAYGLAATACWVLGLPHGLAVLHGKTRRGGLVFDVADVMKDAVVLPQAFISAMDGDDEQEFRQHCLEQFRKTQALDVMIETLQATAEQLARNKA
>CP035458.1|QAY37234.1|872593_873637_+|IS21-family-transposase
MLTKEIYVDIHIRFKQGQSIRKIARELGVSRNTVKKYLHHNALPMYTGRKSTPSKLDSYKPYLIERINQAKPDWLPATVLFDEVKQRGYNGGIAQLRRFIRQFRQQIPAEPLIRFETQPGQQLQIDFTTIRRGKRPLKAFVATLGFSRACFVKFFDNERSSAWQQGLQEAFEYFGGVTKEVLCDNAKALIIKRDAYAEGEHKLHDEMLQMSKDYGFKLMACKPYRAKTKGKVERFNHYLKNSFILPLVTQLRVQNLELDSDIANAKVGPWLERIAHQRIHGTTQEKPADRLVQEVEYLQPLPVMIQQPLAQGATLSMAVVPPSNVINLQHPMSVYESLQFGEHNVTV
>CP035458.1|QAY37235.1|873623_874382_+|AAA-family-ATPase
MLLYKQISELCESFNLQAFEHWSAVADECVREEKSYGDFLLALLKNEQLHRDERTRSMFSRMAGFPSHKELESFDFKFATGVPKQQIKELSTLSFIERRENLVLLGPSGVGKTHLAIGLGIKAVQAKKKTRFITAADLMLQLSTAKRQNKLKQYLSRSIMAPKLLIIDEIGYLPFGREEANLFFNVIAKRYEHGSIILTSNLSFGQWPTAFADDATLTAAMLDRLLHHSHVLQLSGDSYRLKDKRRSGTLPE
>CP035458.1|QAY37236.1|875140_875311_-|ClbS/DfsB-family-four-helix-bundle-protein
MSSIPTTKEELEKAINDSFSKLLIYLKAIPESESRTHSRHYLIINSIKNHGTKNGR
>CP035458.1|QAY37237.1|875494_875974_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MSNFTLTSNDIFEGQLKDKQFAFNGFGHDGDNISPQLAWENAPEGTKSFAVTCFDPDAPTGCGFWHWQVINIPAETTELEQGASGKLAAGLEMRNDYGFNGFGGACPPEGHGMHRYQFTVWALPVEKLDVPDDASCALVSFMLHGMSLAKSTITTTYVR

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Crispr_ID: CP035458_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035458_2

874484-874931

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTACTCGGCAGTGAAG	PILER-CR
TTTCTAAGCTGCCTACTCGGCAGTGAAG	CRISPRCasFinder
TTTCTAAGCTGCCTACTCGGCAGTGAAG	CRT

7 spacers

cas1,cas3f,cas8f,cas5f,cas7f,cas6f

The CRISPR arrays of CP035458_2

>merge|CP035458|2|874484-874931|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCCTACTCGGCAGTGAAGATGTCACTTTTTATCAACTTAGAGATGTCACATTTCTAAGCTGCCTACTCGGCAGTGAAGACCGAGGCACAAACCGCCCAGCAATGCTGAGTTTTCTAAGCTGCCTACTCGGCAGTGAAGTTCCATCCTACGAGTTTGAATGGAGCTGGAGCTTTCTAAGCTGCCTACTCGGCAGTGAAGCAAAAGTATTTTGCCCCGTATTTTGTGGATTATTTCTAAGCTGCCTACTCGGCAGTGAAGGGACGCTTATGAAAAAACGCAGCAGCAAACAATTTCTAAGCTGCCTACTCGGCAGTGAAGTCGGTTTGCGTGAGGGGATGCAGTTAGCACTATTTCTAAGCTGCCTACTCGGCAGTGAAGTTAGATTTTTCTCTTAACAATGAATCTATTATTTTCTAAGCTGCCTACTCGGCAGTGAAG

>CP035458|2|2|874484-874931|PILER-CR
TTTCTAAGCTGCCTACTCGGCAGTGAAG	ATGTCACTTTTTATCAACTTAGAGATGTCACA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	ACCGAGGCACAAACCGCCCAGCAATGCTGAGT
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TTCCATCCTACGAGTTTGAATGGAGCTGGAGC
TTTCTAAGCTGCCTACTCGGCAGTGAAG	CAAAAGTATTTTGCCCCGTATTTTGTGGATTA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	GGACGCTTATGAAAAAACGCAGCAGCAAACAA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TCGGTTTGCGTGAGGGGATGCAGTTAGCACTA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TTAGATTTTTCTCTTAACAATGAATCTATTAT
TTTCTAAGCTGCCTACTCGGCAGTGAAG

>CP035458|2|2|874484-874931|CRISPRCasFinder
TTTCTAAGCTGCCTACTCGGCAGTGAAG	ATGTCACTTTTTATCAACTTAGAGATGTCACA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	ACCGAGGCACAAACCGCCCAGCAATGCTGAGT
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TTCCATCCTACGAGTTTGAATGGAGCTGGAGC
TTTCTAAGCTGCCTACTCGGCAGTGAAG	CAAAAGTATTTTGCCCCGTATTTTGTGGATTA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	GGACGCTTATGAAAAAACGCAGCAGCAAACAA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TCGGTTTGCGTGAGGGGATGCAGTTAGCACTA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TTAGATTTTTCTCTTAACAATGAATCTATTAT
TTTCTAAGCTGCCTACTCGGCAGTGAAG

>CP035458|2|1|874484-874931|CRT
TTTCTAAGCTGCCTACTCGGCAGTGAAG	ATGTCACTTTTTATCAACTTAGAGATGTCACA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	ACCGAGGCACAAACCGCCCAGCAATGCTGAGT
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TTCCATCCTACGAGTTTGAATGGAGCTGGAGC
TTTCTAAGCTGCCTACTCGGCAGTGAAG	CAAAAGTATTTTGCCCCGTATTTTGTGGATTA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	GGACGCTTATGAAAAAACGCAGCAGCAAACAA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TCGGTTTGCGTGAGGGGATGCAGTTAGCACTA
TTTCTAAGCTGCCTACTCGGCAGTGAAG	TTAGATTTTTCTCTTAACAATGAATCTATTAT
TTTCTAAGCTGCCTACTCGGCAGTGAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP035458.1\|QAY37241.1\|881493_882510_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|177883
CP035458.1\|QAY37230.1\|865714_866713_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	pfam09614_cas5f_CAS-I-F	gnl\|CDD\|378221
CP035458.1\|QAY37462.1\|878480_878864_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|224885
CP035458.1\|QAY37234.1\|872593_873637_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
CP035458.1\|QAY37232.1\|867987_871320_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|274201
CP035458.1\|QAY37240.1\|879924_881271_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587
CP035458.1\|QAY37227.1\|863376_863790_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
CP035458.1\|QAY37233.1\|871316_872291_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
CP035458.1\|QAY37238.1\|876072_876867_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP035458.1\|QAY37228.1\|864161_864716_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl\|CDD\|378224
CP035458.1\|QAY37235.1\|873623_874382_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
CP035458.1\|QAY37242.1\|884701_885220_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
CP035458.1\|QAY37229.1\|864717_865707_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
CP035458.1\|QAY37243.1\|885214_885712_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368215
CP035458.1\|QAY37231.1\|866670_867972_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	pfam09611_cas8f_CAS-I-F	gnl\|CDD\|187866
CP035458.1\|QAY37236.1\|875140_875311_-\|ClbS/DfsB-family-four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|377957
CP035458.1\|QAY37226.1\|862373_863324_+\|putative-sulfate-exporter-family-transporter	unknown	unknown	gnl\|CDD\|225411
CP035458.1\|QAY37463.1\|883482_884535_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
CP035458.1\|QAY37239.1\|879169_879712_+\|SPOR-domain-containing-protein	unknown	unknown	gnl\|CDD\|225805
CP035458.1\|QAY37237.1\|875494_875974_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|182339

Protein	Function_ID	Function_description	E-value
CP035458.1\|QAY37241.1\|881493_882510_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|177883	PLN02240, PLN02240, UDP-glucose 4-epimerase.	0
CP035458.1\|QAY37230.1\|865714_866713_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	9.8005e-114
CP035458.1\|QAY37462.1\|878480_878864_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	3.8568e-32
CP035458.1\|QAY37234.1\|872593_873637_+\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.26107e-45
CP035458.1\|QAY37232.1\|867987_871320_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|274201	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST. The helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.	0
CP035458.1\|QAY37240.1\|879924_881271_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	3.10777e-132
CP035458.1\|QAY37227.1\|863376_863790_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	9.93149e-72
CP035458.1\|QAY37233.1\|871316_872291_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	0
CP035458.1\|QAY37238.1\|876072_876867_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	9.15866e-20
CP035458.1\|QAY37228.1\|864161_864716_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	6.13415e-74
CP035458.1\|QAY37235.1\|873623_874382_+\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	1.25041e-146
CP035458.1\|QAY37242.1\|884701_885220_+\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	1.08112e-51
CP035458.1\|QAY37229.1\|864717_865707_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
CP035458.1\|QAY37243.1\|885214_885712_-\|hypothetical-protein	gnl\|CDD\|368215	pfam04970, LRAT, Lecithin retinol acyltransferase. The full-length members of this family, are representatives of a novel class II tumor-suppressor family, designated as H-REV107-like. This domain is the catalytic N-terminal proline-rich region of the protein. The downstream region is a putative C-terminal transmembrane domain which is found to be crucial for cellular localization, but not necessary for the enzyme activity. H-REV107-like proteins are homologous to lecithin retinol acyltransferase (LRAT), an enzyme that catalyzes the transfer of the sn-1 acyl group of phosphatidylcholine to all-trans-retinol and forming a retinyl ester.	0.00157363
CP035458.1\|QAY37231.1\|866670_867972_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|187866	cd09735, Csy1_I-F, CRISPR/Cas system-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins; Predicted subunit of the Cascade complex; signature gene for I-F subtype; also known as Csy1 family.	1.43888e-113
CP035458.1\|QAY37236.1\|875140_875311_-\|ClbS/DfsB-family-four-helix-bundle-protein	gnl\|CDD\|377957	pfam08020, DUF1706, Protein of unknown function (DUF1706). This family contains many hypothetical proteins from bacteria and yeast.	4.3899e-06
CP035458.1\|QAY37226.1\|862373_863324_+\|putative-sulfate-exporter-family-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	7.35928e-52
CP035458.1\|QAY37463.1\|883482_884535_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	4.07785e-48
CP035458.1\|QAY37239.1\|879169_879712_+\|SPOR-domain-containing-protein	gnl\|CDD\|225805	COG3266, DamX, Uncharacterized protein conserved in bacteria [Function unknown].	3.62803e-21
CP035458.1\|QAY37237.1\|875494_875974_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	6.61408e-64

>CP035458.1|QAY37235.1|873623_874382_+|AAA-family-ATPase
MLLYKQISELCESFNLQAFEHWSAVADECVREEKSYGDFLLALLKNEQLHRDERTRSMFSRMAGFPSHKELESFDFKFATGVPKQQIKELSTLSFIERRENLVLLGPSGVGKTHLAIGLGIKAVQAKKKTRFITAADLMLQLSTAKRQNKLKQYLSRSIMAPKLLIIDEIGYLPFGREEANLFFNVIAKRYEHGSIILTSNLSFGQWPTAFADDATLTAAMLDRLLHHSHVLQLSGDSYRLKDKRRSGTLPE
>CP035458.1|QAY37234.1|872593_873637_+|IS21-family-transposase
MLTKEIYVDIHIRFKQGQSIRKIARELGVSRNTVKKYLHHNALPMYTGRKSTPSKLDSYKPYLIERINQAKPDWLPATVLFDEVKQRGYNGGIAQLRRFIRQFRQQIPAEPLIRFETQPGQQLQIDFTTIRRGKRPLKAFVATLGFSRACFVKFFDNERSSAWQQGLQEAFEYFGGVTKEVLCDNAKALIIKRDAYAEGEHKLHDEMLQMSKDYGFKLMACKPYRAKTKGKVERFNHYLKNSFILPLVTQLRVQNLELDSDIANAKVGPWLERIAHQRIHGTTQEKPADRLVQEVEYLQPLPVMIQQPLAQGATLSMAVVPPSNVINLQHPMSVYESLQFGEHNVTV
>CP035458.1|QAY37233.1|871316_872291_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MKKDFSPSELKTILHSKRANLYYLQHCRVLVNSGRVEYVTDEGKESLYWNIPIANTTAIMLGTGTSVTQAAMRELAKAGVLVGFCGGGGTPLFSGNEVQVDVSWLLPQSEYRPTEYLQQWVSFWFDDNARLTAAKAFQHQRIKQIHKQWQRLENKHDFAYNAELLDGALQRFSDNIETCQTSQDLLLLEATTTKTLYKIACHAVQYGEFTRSERGNSTDIANRFLDHGNYLAYGLAATACWVLGLPHGLAVLHGKTRRGGLVFDVADVMKDAVVLPQAFISAMDGDDEQEFRQHCLEQFRKTQALDVMIETLQATAEQLARNKA
>CP035458.1|QAY37232.1|867987_871320_-|type-I-F-CRISPR-associated-helicase-Cas3
MNILLISECNKQALPETRRILDQFAERKGSRTWQTPITFEGLKTLRMLLKKTARRNTAVACYWIHGKNQTELLWIVGNRRKFNEQGTVPTNITERDILRTQDENGMNSIQSVALLAALAGLFHDFGKANQLFQNKLKPKSKVRFEPYRHEWISLWLFVAFVNQRCDSEWLDDLAQSRLPNDTELLAQLDPERTFIIEDLLPIAQCVAWLIVSHHRLPKYLLGNVNIDVWRQGMDAAWNALNHKSETLGEKEFKQNIQFPFGTPFASATWRHKAKEIAKRANQLPNFTEYAQLEKAFPLHLARMALMLADHTYSADVAHENWQDLNYQANANTDRKTGKIKQKLDEHCIGVAHNAYILARTLPRLRSVMPAITQHKGFKRRCKNAKFRWQDKAYDCAYAIAELSEQNGFFGVNMASTGKGKTFANARIMYGLSNPKLGCRFSVALGLRTLTLQTGDALQQRLCLDSDDVAVHIGSQAVHDLFYRDKKAQQAALDNHEAAVRTGSESELLFSEHNYVRYDGEVDNHYLQRWLKEKGAIHKLVSAPISVSTIDHLMPVSEGITGGQQIAPMMRLLTSDLVLDEPDDFSLDDDPALGRLVYFAGLLGSRVLLSSATLPPALVNHLFACYQAGRAQYNQVTGQQHQKPVCCAWFDEFGVQSNQADGIAQFNQYHQMFTQSRKQALDKYQQPLHVGNWLNIDEKASPDQSVIELFTRTLYQGIYQLAAEHHTQSTQPNSNGKTVSAGIIRMANIEPLVAVANSLFSLPAKENTRIHYCVYHSQHPLAVRSAIENQLDQLLQRDRVDLQDIVTKPTVERVLIQYSEQHHIFVVLATPVAEVGRDHDYDWAIVEPSSMRSIIQLAGRVQRHRQLVPNGANILVLNKNIKALKQSSVAYTSPGFESDKLYYRIDGHRFPYLQLTDHDLRNQLHLRTLKNISSEPRFICPKPLVDEVQQRVIGFIELEHQATLFYMQQYLKPWWQSHCAHLIGELQKQTPFRQSRPSVNYIMMLDDDSDYITLQVWDNASQSWIDSGLLTPFSERELASGISLWGSGCLTDEIEQLAEEYQLEISTTCERFAAINLPENSASDCGKPWLYDPILGVFRGRDITPLNHDSV
>CP035458.1|QAY37231.1|866670_867972_-|type-I-F-CRISPR-associated-protein-Csy1
MPETLAQNIKTFIAERYQTKLEEKQKAYDKNKAAAVTAEDFDRIESQFLADKEKLLQQFELNAWIDNAARRANQISMATHALKFTNSSAKGSNVLAYDLSHDARYLDTEIIQEKAIDAVGNAAALDVARFLQLTDENGLSLLSYLAKADHRPLALIAKSDEELIHWLDGLKQALRDTSPSSHVLGKQIYFPVSDNEYHLLAPLYSSSLAQVLFDAVQYSRFSQEMKAIREAKRHNDFHPQPLIAYPNLAVTVSGGSKPQNVSQLNNKRSGKTYLFSAAPPNWQAQNKPPLGLDSILRHRDIYYHTQEPITRLTQFLIKLNAASTESNMRIRHYIVNTVDEVIDQILLVAAKWQQLPAGWSDKSDLPLAQRRWLDPNNSQWDRFDDHWQQAIAENVGLWLKDKVNKGSQNHFTLGQIEAMEWQKQCLNALQEIA
>CP035458.1|QAY37230.1|865714_866713_-|type-I-F-CRISPR-associated-protein-Csy2
MAKTVLKCITGDRIMEQYLVLKQIDVTNANAISGFTYGFPAITHFLGYVHALSRKLTHRGITLSDVAVVCHQHQTHAYRESSYEPYSFALTRNPLTKEGKTAPINEEGRMSMTVSLIIKASGIPNHVDSEKQATCELIKQLAEQQKLAGGRIVSIRSCQLAKDNATAKTLLRGLLPGFVLVDRSDLMAINEQNQETVSHWLSFSALKYQSVELKKYDESQDRNESYIEWQRIAKPAGYLVPIQIGYKAISPLYEAGTVANVRDIETSVSFVEAVHSIGEWVGAPSRISSMDQILWRYHYHAPFYVAHSQQQSMNGDLMPISPDNKIEYNEDY
>CP035458.1|QAY37229.1|864717_865707_-|type-I-F-CRISPR-associated-protein-Csy3
MTMSKLETPSVLAFEAKLACSDAIMFAGNWEERDTVASWAPILVTEKSVRGTISNRLKGAKASKIDAEVEKANLQTVDNAALNFDTDTLKVTFSLRVLGNLGVPSTCNNPDYQQALASKITTYVQEEGFTELATRYALNLANGRFLWRNRVGAEQVEVRISHQEQTWCFDALNYSLRDFDERDQDIKAIATVIEQGLMGEKPTLLTVEAFVQLGEGQTVFPSQELVMNTGDKKSKYLYQLSGQAAMHSQKIGNALRTIDTWYPAAGECGPIAIEPYGSVTNRGIAYRKPKEKTDFYTLLDGWMLKDKQPTTCELHYMMAMLIRGGVFGE
>CP035458.1|QAY37228.1|864161_864716_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDYYLDIQVEPDLEITAPALLNNLFAKFHRAMSQCCIGRIAVSFPSYNKSLGETLRLHGTQADLDELMALPWLKGLRDYTKVSAILPIPRDIAGHRTVHRVQKKSPHNLRKRAVAKGRMTEQEALTKIPDALQERLALPFIQMQSLSNKQVMRIYVALGEIQSEPVLGEFSSYGMSRTSTIPWF
>CP035458.1|QAY37227.1|863376_863790_-|aminoacyl-tRNA-hydrolase
MLTISNNVTISDWEIELNAIRSAGNGGQNVNKVATAIHLRFDIKKSSLPAIYKEKLLKLSDSRISSDGVIIIKSQQYRTQLQNKEAALERLKELILSAMVVQKARRPTKPTKSSQRRRLESKTKRGSTKTMRKKVDY
>CP035458.1|QAY37226.1|862373_863324_+|putative-sulfate-exporter-family-transporter
MLFKKIFARLQPSDALFFIAAFFCLLPFVSSPIALILGFSLASLGLVPTQFNIAAATKKLLSYSIIGLGFGIHLNEAIEASKQGLGLIVCSIFFTLILGWVVTRLMGLDKKTGHLIASGTAICGGSAIAAVAPAINAKDDEISLALATVFVLNAIALFIFPVIGHLLDMSQHAFGTWAAIAIHDTSSVVGAAGSYGDEALKTATTLKLARALWIIPVAFISALLFKGNSKKISVPFFIVFYCLAIVFAHFVPSLQPAYNMIFAFSKRLLVMCLFLIGSGITINKLRNAGAKPLLLGVILWLAIGGASLAYIEATMA
>CP035458.1|QAY37236.1|875140_875311_-|ClbS/DfsB-family-four-helix-bundle-protein
MSSIPTTKEELEKAINDSFSKLLIYLKAIPESESRTHSRHYLIINSIKNHGTKNGR
>CP035458.1|QAY37237.1|875494_875974_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MSNFTLTSNDIFEGQLKDKQFAFNGFGHDGDNISPQLAWENAPEGTKSFAVTCFDPDAPTGCGFWHWQVINIPAETTELEQGASGKLAAGLEMRNDYGFNGFGGACPPEGHGMHRYQFTVWALPVEKLDVPDDASCALVSFMLHGMSLAKSTITTTYVR
>CP035458.1|QAY37238.1|876072_876867_+|AraC-family-transcriptional-regulator
MATSAIVITQYQGQQAQNLRNVPILLPSIVAVEQGEKQFQWHGRWIRFHKKNWLLIPAHSRITFVNNPHQTQFRSTQISFLIPPTAEMIQLSHQNADTVSNHLDSPEFIINDEGRYLWQLLLSMPKELSQAIQQQLVNGLYQYLAENGQLHLLYAPQEISWTEKLTQFFSQDPSQNYTIEQVCQQFGLSKATLMRRLNDESTQFREVLAQVRMGHALSLLQEKSHTVLELAQQCGYQSEVRFTQRFQKQFGLSPKQYQKTLHPM
>CP035458.1|QAY37462.1|878480_878864_-|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MLKVILYTESVSCGFPSPAEGHQETLELEDYLIRHPNATFFLRACGESMVGAGIYDGDLLVVDRAEEVKPGRIVIARIYDEFTCKRLVRYDESWWLQPENPTLQAFPMPEDSEIFGVVTRNIHNLLN
>CP035458.1|QAY37239.1|879169_879712_+|SPOR-domain-containing-protein
MKLLSRKTVPALLASILLAGCSSADNPCDTGYLMPSKINGENFQCQQPETTAPETDYNDQTTDNTVTEEPAITEDNSVSSDEAYGSFDPSHYTVQVLALKRESDLHNYISLLPTNEPVWVNWNRVDGQSWFVVIMGDYPSREAARQAIGYLPSQVQAQGPFIRSFANVQADKETNVVRMR
>CP035458.1|QAY37240.1|879924_881271_-|DEAD/DEAH-box-helicase
MHFKDLGLDPRLLKKLSHLAFDQATEIQRTAIPVAILGKDILASSKTGSGKTLAFLLPAMQRMYRSKPFTRRDPRVLILTPTRELAKQVFAQLKPLNAGTPYDAALIVGGENFNDQVKALRKDPMFVVATPGRLADHLEHRSTYLDGLEMLILDEADRMLDLGFEKELRRIHEAASHRRRQTLMFSATLDHPEVVEMAHEMLNAPKRISIGHSAEEHKDITQRFILCDNLTHKEALLNKILETEDYNQMIIFTATRADTDRLTKELNDRKLKAVALSGNLNQTQRNSIMSQFERFCHKILVTTDIASRGLDISNVSHVINFDLPKHAEEYVHRVGRTGRAGNKGDAISFVGPKDWKSFKNIEAFLQQSIEFTAIDGLKAKFKGFKIEQKKKFNKKPTEQNNQKKKTQAAKPKRHIDKRFYDNQAVGHEVFMPKKKPRNVAAEIDKDQE
>CP035458.1|QAY37241.1|881493_882510_-|UDP-glucose-4-epimerase-GalE
MRVLVTGGMGYIGSHTCVQMIEAGMTPIILDNLYNSKETVLERVENLTGVRPAFYKGDIRDRAFLDSVFAENEIDAVIHFAGLKAVGESVEKPLEYYDNNVHGTLVLVEAMRAAGVNSLIFSSSATVYGDPASVPITEDFPTSATNPYGRSKLMVEECLTDIQHAYPEMSITLLRYFNPVGSHKSGTMGEDPQGIPNNLMPFISQVAVGRREFLSVFGDDYPTVDGTGVRDYIHVVDLADGHIAALKYKGSEAGLHIYNLGTGNGNSVLQMVSAFEKASGAKVAYKIAPRRPGDIAECWADPAKAKRELHWEATHTIEDMTADTWRWQSTNPNGYPDA
>CP035458.1|QAY37463.1|883482_884535_+|GGDEF-domain-containing-protein
MATLVKSTQLESVNFAYIELSKNTLQRQLSLLFTSSGIICTLVAFAYFVAKTSLVSLYSALLGLSISYTLAIFNRINVNPKVLMWIFILSTTLACITGYSFSETHHISNTIGLTIPLLCFFALKQKTATWYSGLFGCCYVILSISEIGEKQLQLNDALQNMSAYSLVFVMAYLLAKHRNEAINCVKQTATNDFLTGLYNREGLLPIYQAEAARSERYLKDFSMLLLSVDDFKNINDRYGLETGDKVLMMLTKCLQQLSRKEDTIARLGGTEFCLLLPDTSLEQAEKFALRLQEQVNSWVLELESGHRISVTLSMGLTPIQFREFNYDYIKADNAVMRAKHWGGNQLAISE
>CP035458.1|QAY37242.1|884701_885220_+|NUDIX-hydrolase
MTTVQTHYQWKCFSIDEEQHQLPDGRIIPFTTIKHPGAVVIIPIDRNGDLILVHQYRPAIKQWIYEFPAGTLEDKENILACAQRELAEEAKLQAKNWQSLGELLPVPGFCDEIQYLFLAQELSEANGELDDDEIMDVVTLSITEFEQKIAANQIQDNKTLAAYCKAKAMQLL
>CP035458.1|QAY37243.1|885214_885712_-|hypothetical-protein
MTISGYQVQPGDIVAVDFGRYDHWALVSDKVCHQGKRMLISATKRNGTVMEETWDEVTQGQKVVLSKLHCHNDVSGSLEKARSQIGVWQYSVYKRNCEHFIYWVLSDKLRSKQVIGGVSGAVLGAIGVVTLSKKPSVLKVLGGAWAGLSSGVILAKASNKTRKKS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP035458_1	1.2\|863965\|31\|CP035458\|CRISPRCasFinder	863965-863995	31	CP035459.1	35919-35949	0	1.0
CP035458_1	1.2\|863965\|31\|CP035458\|CRISPRCasFinder	863965-863995	31	CP035461.1	35553-35583	0	1.0
CP035458_1	1.4\|863979\|25\|CP035458\|PILER-CR	863979-864003	25	CP035459.1	35920-35944	0	1.0
CP035458_1	1.4\|863979\|25\|CP035458\|PILER-CR	863979-864003	25	CP035461.1	35558-35582	0	1.0
CP035458_2	2.6\|874812\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874812-874843	32	CP035461.1	34289-34320	0	1.0
CP035458_2	2.7\|874872\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874872-874903	32	CP035461.1	27563-27594	0	1.0
CP035458_2	2.5\|874752\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874752-874783	32	CP035459.1	26909-26940	1	0.969
CP035458_2	2.6\|874812\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874812-874843	32	CP035460.1	20406-20437	1	0.969

1. spacer 1.2|863965|31|CP035458|CRISPRCasFinder matches to position: 35919-35949, mismatch: 0, identity: 1.0

gagaaaggaacatcagagtgcgcagatgtag	CRISPR spacer
gagaaaggaacatcagagtgcgcagatgtag	Protospacer
*******************************

2. spacer 1.2|863965|31|CP035458|CRISPRCasFinder matches to position: 35553-35583, mismatch: 0, identity: 1.0

gagaaaggaacatcagagtgcgcagatgtag	CRISPR spacer
gagaaaggaacatcagagtgcgcagatgtag	Protospacer
*******************************

3. spacer 1.4|863979|25|CP035458|PILER-CR matches to position: 35920-35944, mismatch: 0, identity: 1.0

agaaaggaacatcagagtgcgcaga	CRISPR spacer
agaaaggaacatcagagtgcgcaga	Protospacer
*************************

4. spacer 1.4|863979|25|CP035458|PILER-CR matches to position: 35558-35582, mismatch: 0, identity: 1.0

agaaaggaacatcagagtgcgcaga	CRISPR spacer
agaaaggaacatcagagtgcgcaga	Protospacer
*************************

5. spacer 2.6|874812|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to position: 34289-34320, mismatch: 0, identity: 1.0

tcggtttgcgtgaggggatgcagttagcacta	CRISPR spacer
tcggtttgcgtgaggggatgcagttagcacta	Protospacer
********************************

6. spacer 2.7|874872|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to position: 27563-27594, mismatch: 0, identity: 1.0

ttagatttttctcttaacaatgaatctattat	CRISPR spacer
ttagatttttctcttaacaatgaatctattat	Protospacer
********************************

7. spacer 2.5|874752|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to position: 26909-26940, mismatch: 1, identity: 0.969

ggacgcttatgaaaaaacgcagcagcaaacaa	CRISPR spacer
ggacgcttatgaaaaaacgcagcaacaaacaa	Protospacer
************************.*******

8. spacer 2.6|874812|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to position: 20406-20437, mismatch: 1, identity: 0.969

tcggtttgcgtgaggggatgcagttagcacta	CRISPR spacer
tcggtttgcgtgaggggatgcagttagcatta	Protospacer
*****************************.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP035458_1	1.2\|863965\|31\|CP035458\|CRISPRCasFinder	863965-863995	31	NZ_CP035461	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence	35553-35583	0	1.0
CP035458_1	1.2\|863965\|31\|CP035458\|CRISPRCasFinder	863965-863995	31	NZ_CP021155	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence	50678-50708	0	1.0
CP035458_1	1.2\|863965\|31\|CP035458\|CRISPRCasFinder	863965-863995	31	NZ_CP035459	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence	35919-35949	0	1.0
CP035458_1	1.4\|863979\|25\|CP035458\|PILER-CR	863979-864003	25	NZ_CP021155	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence	50679-50703	0	1.0
CP035458_1	1.4\|863979\|25\|CP035458\|PILER-CR	863979-864003	25	NZ_CP035459	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence	35920-35944	0	1.0
CP035458_1	1.4\|863979\|25\|CP035458\|PILER-CR	863979-864003	25	NZ_CP035461	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence	35558-35582	0	1.0
CP035458_2	2.2\|874572\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874572-874603	32	NZ_CP021156	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-4, complete sequence	30244-30275	0	1.0
CP035458_2	2.6\|874812\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874812-874843	32	NZ_CP021155	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence	51948-51979	0	1.0
CP035458_2	2.6\|874812\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874812-874843	32	NZ_CP035461	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence	34289-34320	0	1.0
CP035458_2	2.7\|874872\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874872-874903	32	NZ_CP021155	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence	58692-58723	0	1.0
CP035458_2	2.7\|874872\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874872-874903	32	NZ_CP035461	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence	27563-27594	0	1.0
CP035458_2	2.5\|874752\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874752-874783	32	NZ_CP021154	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-2, complete sequence	47380-47411	1	0.969
CP035458_2	2.5\|874752\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874752-874783	32	NZ_CP035459	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence	26909-26940	1	0.969
CP035458_2	2.6\|874812\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874812-874843	32	NZ_CP021153	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence	16762-16793	1	0.969
CP035458_2	2.6\|874812\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874812-874843	32	NZ_CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	20406-20437	1	0.969
CP035458_2	2.7\|874872\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874872-874903	32	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	377598-377629	7	0.781
CP035458_2	2.4\|874692\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874692-874723	32	MT178275	Klebsiella virus KpS8, complete genome	994-1025	8	0.75
CP035458_2	2.4\|874692\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874692-874723	32	MT939253	Klebsiella phage vB_KpnM_Seu621, complete genome	993-1024	8	0.75
CP035458_2	2.4\|874692\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874692-874723	32	MK024806	Proteus phage Mydo, complete genome	8437-8468	8	0.75
CP035458_2	2.4\|874692\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874692-874723	32	NC_048656	Klebsiella phage vB_KpnM_BIS47, complete genome	131832-131863	8	0.75
CP035458_2	2.4\|874692\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874692-874723	32	NC_028659	Klebsiella phage vB_KpnM_KB57, complete genome	994-1025	8	0.75
CP035458_2	2.7\|874872\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874872-874903	32	NZ_CP013708	Clostridium botulinum strain F634 plasmid pRSJ2_1, complete sequence	6367-6398	8	0.75
CP035458_2	2.4\|874692\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874692-874723	32	NC_021856	Bacillus phage phiNIT1 DNA, complete genome	62246-62277	9	0.719
CP035458_2	2.2\|874572\|32\|CP035458\|PILER-CR,CRISPRCasFinder,CRT	874572-874603	32	MN694560	Marine virus AFVG_250M172, complete genome	16893-16924	19	0.406

1. spacer 1.2|863965|31|CP035458|CRISPRCasFinder matches to NZ_CP035461 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence) position: , mismatch: 0, identity: 1.0

gagaaaggaacatcagagtgcgcagatgtag	CRISPR spacer
gagaaaggaacatcagagtgcgcagatgtag	Protospacer
*******************************

2. spacer 1.2|863965|31|CP035458|CRISPRCasFinder matches to NZ_CP021155 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence) position: , mismatch: 0, identity: 1.0

gagaaaggaacatcagagtgcgcagatgtag	CRISPR spacer
gagaaaggaacatcagagtgcgcagatgtag	Protospacer
*******************************

3. spacer 1.2|863965|31|CP035458|CRISPRCasFinder matches to NZ_CP035459 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence) position: , mismatch: 0, identity: 1.0

gagaaaggaacatcagagtgcgcagatgtag	CRISPR spacer
gagaaaggaacatcagagtgcgcagatgtag	Protospacer
*******************************

4. spacer 1.4|863979|25|CP035458|PILER-CR matches to NZ_CP021155 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence) position: , mismatch: 0, identity: 1.0

agaaaggaacatcagagtgcgcaga	CRISPR spacer
agaaaggaacatcagagtgcgcaga	Protospacer
*************************

5. spacer 1.4|863979|25|CP035458|PILER-CR matches to NZ_CP035459 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence) position: , mismatch: 0, identity: 1.0

agaaaggaacatcagagtgcgcaga	CRISPR spacer
agaaaggaacatcagagtgcgcaga	Protospacer
*************************

6. spacer 1.4|863979|25|CP035458|PILER-CR matches to NZ_CP035461 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence) position: , mismatch: 0, identity: 1.0

agaaaggaacatcagagtgcgcaga	CRISPR spacer
agaaaggaacatcagagtgcgcaga	Protospacer
*************************

7. spacer 2.2|874572|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021156 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-4, complete sequence) position: , mismatch: 0, identity: 1.0

accgaggcacaaaccgcccagcaatgctgagt	CRISPR spacer
accgaggcacaaaccgcccagcaatgctgagt	Protospacer
********************************

8. spacer 2.6|874812|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021155 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence) position: , mismatch: 0, identity: 1.0

tcggtttgcgtgaggggatgcagttagcacta	CRISPR spacer
tcggtttgcgtgaggggatgcagttagcacta	Protospacer
********************************

9. spacer 2.6|874812|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035461 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence) position: , mismatch: 0, identity: 1.0

tcggtttgcgtgaggggatgcagttagcacta	CRISPR spacer
tcggtttgcgtgaggggatgcagttagcacta	Protospacer
********************************

10. spacer 2.7|874872|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021155 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-3, complete sequence) position: , mismatch: 0, identity: 1.0

ttagatttttctcttaacaatgaatctattat	CRISPR spacer
ttagatttttctcttaacaatgaatctattat	Protospacer
********************************

11. spacer 2.7|874872|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035461 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-3, complete sequence) position: , mismatch: 0, identity: 1.0

ttagatttttctcttaacaatgaatctattat	CRISPR spacer
ttagatttttctcttaacaatgaatctattat	Protospacer
********************************

12. spacer 2.5|874752|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021154 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-2, complete sequence) position: , mismatch: 1, identity: 0.969

ggacgcttatgaaaaaacgcagcagcaaacaa	CRISPR spacer
ggacgcttatgaaaaaacgcagcaacaaacaa	Protospacer
************************.*******

13. spacer 2.5|874752|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035459 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-1, complete sequence) position: , mismatch: 1, identity: 0.969

ggacgcttatgaaaaaacgcagcagcaaacaa	CRISPR spacer
ggacgcttatgaaaaaacgcagcaacaaacaa	Protospacer
************************.*******

14. spacer 2.6|874812|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021153 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence) position: , mismatch: 1, identity: 0.969

tcggtttgcgtgaggggatgcagttagcacta	CRISPR spacer
tcggtttgcgtgaggggatgcagttagcatta	Protospacer
*****************************.**

15. spacer 2.6|874812|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035460 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence) position: , mismatch: 1, identity: 0.969

tcggtttgcgtgaggggatgcagttagcacta	CRISPR spacer
tcggtttgcgtgaggggatgcagttagcatta	Protospacer
*****************************.**

16. spacer 2.7|874872|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 7, identity: 0.781

ttagatttttctcttaacaatgaatctattat	CRISPR spacer
gatgctttttctcctaaaaatgaatctattgt	Protospacer
   * ********.*** ************.*

17. spacer 2.4|874692|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to MT178275 (Klebsiella virus KpS8, complete genome) position: , mismatch: 8, identity: 0.75

caaaagtattttgccccgtattttgtggatta	CRISPR spacer
gcaatgtattttgcgccgtattttgtagcaaa	Protospacer
  ** ********* ***********.*   *

18. spacer 2.4|874692|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to MT939253 (Klebsiella phage vB_KpnM_Seu621, complete genome) position: , mismatch: 8, identity: 0.75

caaaagtattttgccccgtattttgtggatta	CRISPR spacer
gcaatgtattttgcgccgtattttgtagcaaa	Protospacer
  ** ********* ***********.*   *

19. spacer 2.4|874692|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to MK024806 (Proteus phage Mydo, complete genome) position: , mismatch: 8, identity: 0.75

caaaagtattttgccccgtattttgtggatta	CRISPR spacer
gcaatgtattttgcgccgtattttgtagcaaa	Protospacer
  ** ********* ***********.*   *

20. spacer 2.4|874692|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NC_048656 (Klebsiella phage vB_KpnM_BIS47, complete genome) position: , mismatch: 8, identity: 0.75

caaaagtattttgccccgtattttgtggatta	CRISPR spacer
gcaatgtattttgcgccgtattttgtagcaaa	Protospacer
  ** ********* ***********.*   *

21. spacer 2.4|874692|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NC_028659 (Klebsiella phage vB_KpnM_KB57, complete genome) position: , mismatch: 8, identity: 0.75

caaaagtattttgccccgtattttgtggatta	CRISPR spacer
gcaatgtattttgcgccgtattttgtagcaaa	Protospacer
  ** ********* ***********.*   *

22. spacer 2.7|874872|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013708 (Clostridium botulinum strain F634 plasmid pRSJ2_1, complete sequence) position: , mismatch: 8, identity: 0.75

ttagatttttctcttaacaatgaatctattat	CRISPR spacer
tcaatatcttctcttaacattgaatttattag	Protospacer
*.*.  *.*********** *****.*****

23. spacer 2.4|874692|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to NC_021856 (Bacillus phage phiNIT1 DNA, complete genome) position: , mismatch: 9, identity: 0.719

caaaagtattttgccccgtattttgtggatta	CRISPR spacer
tctatgtatattgccccgtcttttgtggcatc	Protospacer
.  * **** ********* ********  *

24. spacer 2.2|874572|32|CP035458|PILER-CR,CRISPRCasFinder,CRT matches to MN694560 (Marine virus AFVG_250M172, complete genome) position: , mismatch: 19, identity: 0.406

accgaggcacaaaccgcccagcaatgctgagt---------------	CRISPR spacer
---------------tctcagcaatgctgggcagtttgtaagaatat	Protospacer
                *.***********.*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

91876 : 100474

Vibrio_phage(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37421.1\|91876_92230_-	DUF1364 domain-containing protein	A0A2I7RNU4	Vibrio_phage	2.5e-20	45.2
QAY36643.1\|92271_92631_-	hypothetical protein	NA	NA	NA	NA
QAY36644.1\|92996_93584_-	DUF1367 family protein	H9C173	Pectobacterium_phage	8.8e-47	46.7
QAY36645.1\|93583_94138_-	hypothetical protein	NA	NA	NA	NA
QAY36646.1\|94130_94790_-	hypothetical protein	W6MVG8	Pseudomonas_phage	1.9e-10	35.3
QAY36647.1\|94812_95718_-	hypothetical protein	A0A1W6JP67	Staphylococcus_phage	3.3e-24	31.6
QAY36648.1\|95856_96168_-	hypothetical protein	NA	NA	NA	NA
QAY36649.1\|96477_97194_+	helix-turn-helix domain-containing protein	U5P0T5	Shigella_phage	1.3e-28	42.9
QAY36650.1\|97625_97985_+	hypothetical protein	NA	NA	NA	NA
QAY36651.1\|98054_98912_+	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	6.6e-67	56.4
QAY36652.1\|98911_100474_+	homogentisate 1,2-dioxygenase	A0A2H4J6P1	uncultured_Caudovirales_phage	2.5e-80	38.7

DBSCAN-SWA_2

184612 : 253987

Mycobacterium_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY36730.1\|184612_185409_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	6.3e-32	37.7
QAY36731.1\|185480_186617_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	2.8e-17	32.2
QAY36732.1\|186678_187104_-	copper resistance protein NlpE	NA	NA	NA	NA
QAY36733.1\|187280_187586_-	hypothetical protein	NA	NA	NA	NA
QAY36734.1\|187861_188740_-	LysR family transcriptional regulator	NA	NA	NA	NA
QAY36735.1\|188843_190181_+	MATE family efflux transporter	NA	NA	NA	NA
QAY36736.1\|190243_191182_-	LysR family transcriptional regulator	NA	NA	NA	NA
QAY36737.1\|191408_193199_+	sodium:proton antiporter	NA	NA	NA	NA
QAY36738.1\|193389_193719_+	multidrug efflux SMR transporter	NA	NA	NA	NA
QAY36739.1\|193758_193995_+	hypothetical protein	NA	NA	NA	NA
QAY36740.1\|194061_194472_+	copper chaperone PCu(A)C	NA	NA	NA	NA
QAY36741.1\|194464_195355_-	phytanoyl-CoA dioxygenase	NA	NA	NA	NA
QAY36742.1\|195320_196589_-	hypothetical protein	NA	NA	NA	NA
QAY36743.1\|196606_197290_-	acyltransferase	NA	NA	NA	NA
QAY36744.1\|197319_198366_-	glycosyltransferase	NA	NA	NA	NA
QAY36745.1\|198481_199561_-	DUF4056 domain-containing protein	NA	NA	NA	NA
QAY37426.1\|199572_200667_-	hypothetical protein	NA	NA	NA	NA
QAY36746.1\|200712_201561_-	TonB-dependent receptor	NA	NA	NA	NA
QAY36747.1\|201776_201983_-	DUF3283 family protein	NA	NA	NA	NA
QAY36748.1\|202044_202803_-	hypothetical protein	NA	NA	NA	NA
QAY36749.1\|203371_204082_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
QAY37427.1\|204324_205818_+\|transposase	IS1 family transposase	NA	NA	NA	NA
QAY36750.1\|206313_207264_+	transaldolase	M4SIN4	Cyanophage	6.7e-12	29.7
QAY36751.1\|207362_209357_+	transketolase	NA	NA	NA	NA
QAY36752.1\|209866_211840_+	amidohydrolase	NA	NA	NA	NA
QAY36753.1\|211904_212801_-	DUF808 domain-containing protein	NA	NA	NA	NA
QAY37428.1\|213527_213722_+	hypothetical protein	NA	NA	NA	NA
QAY36754.1\|213730_214930_+\|transposase	IS91 family transposase	NA	NA	NA	NA
QAY36755.1\|215806_216781_-	nucleoside hydrolase	NA	NA	NA	NA
QAY36756.1\|216964_218221_-	adenylosuccinate synthetase	L7Y4J5	Megavirus	1.3e-47	31.0
QAY36757.1\|218377_219292_+	LysR family transcriptional regulator	NA	NA	NA	NA
QAY36758.1\|220059_220856_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	1.4e-31	37.3
QAY36759.1\|221688_221901_+	hypothetical protein	NA	NA	NA	NA
QAY36760.1\|221837_222634_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	1.1e-31	37.3
QAY36761.1\|223365_224259_-	proline/glycine betaine ABC transporter permease	NA	NA	NA	NA
QAY36762.1\|224417_225419_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
QAY36763.1\|225775_226588_+	sugar-phosphatase	NA	NA	NA	NA
QAY36764.1\|226686_226920_-	hypothetical protein	NA	NA	NA	NA
QAY36765.1\|226924_227296_-	NirD/YgiW/YdeI family stress tolerance protein	A0A1I9LJU6	Stx_converting_phage	3.3e-15	45.0
QAY36766.1\|227538_228150_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
QAY36767.1\|228349_229456_+	efflux RND transporter periplasmic adaptor subunit	S5VL44	Leptospira_phage	6.4e-06	23.8
QAY36768.1\|229459_232510_+	efflux RND transporter permease subunit	NA	NA	NA	NA
QAY36769.1\|232575_233466_-	DUF535 domain-containing protein	NA	NA	NA	NA
QAY36770.1\|234244_235216_-	arginase	NA	NA	NA	NA
QAY37429.1\|235261_235996_-	IclR family transcriptional regulator	NA	NA	NA	NA
QAY36771.1\|236380_237103_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
QAY36772.1\|237254_238790_-	porin	NA	NA	NA	NA
QAY36773.1\|239023_239602_-	DJ-1 family protein	NA	NA	NA	NA
QAY37430.1\|239611_240244_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
QAY36774.1\|240236_241211_-	sugar kinase	NA	NA	NA	NA
QAY36775.1\|241356_242211_-	tagatose bisphosphate family class II aldolase	NA	NA	NA	NA
QAY36776.1\|242491_244030_-	DUF2264 domain-containing protein	NA	NA	NA	NA
QAY36777.1\|244218_245850_-	arylsulfatase	NA	NA	NA	NA
QAY36778.1\|245921_247175_-	anaerobic sulfatase maturase	NA	NA	NA	NA
QAY36779.1\|247434_250515_+	chondroitinase	NA	NA	NA	NA
QAY36780.1\|250649_251204_+	hypothetical protein	NA	NA	NA	NA
QAY36781.1\|251243_251546_-	hypothetical protein	NA	NA	NA	NA
QAY36782.1\|252994_253987_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

295430 : 383267

Mycobacterium_phage(18.75%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY36824.1\|295430_295832_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	1.7e-25	49.2
QAY36825.1\|295927_296758_+	methyltransferase domain-containing protein	NA	NA	NA	NA
QAY36826.1\|296778_298452_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
QAY36827.1\|298519_299986_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
QAY36828.1\|300276_300582_+	hypothetical protein	NA	NA	NA	NA
QAY36829.1\|300587_301538_-	HTH-type transcriptional regulator TreR	C6ZCU4	Enterobacteria_phage	4.9e-15	26.7
QAY36830.1\|301661_302096_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
QAY36831.1\|302162_303047_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
QAY36832.1\|303036_303819_-	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
QAY36833.1\|303838_304312_-	PTS N-acetylgalactosamine transporter subunit IIB	NA	NA	NA	NA
QAY36834.1\|304385_305162_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
QAY36835.1\|305565_306501_+	DUF535 domain-containing protein	NA	NA	NA	NA
QAY36836.1\|306671_307468_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	1.1e-31	37.3
QAY36837.1\|307565_307748_-	hypothetical protein	NA	NA	NA	NA
QAY36838.1\|308070_308866_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	6.3e-32	37.7
QAY36839.1\|309100_310192_-	choloylglycine hydrolase family protein	A0A1J0F9I3	Only_Syngen_Nebraska_virus	6.9e-29	28.4
QAY36840.1\|310354_311716_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.9e-156	71.5
QAY36841.1\|312181_313486_+	serine dehydratase subunit alpha family protein	NA	NA	NA	NA
QAY36842.1\|313599_314685_-\|transposase	transposase	Q9G0F2	Phage_Gifsy-1	5.1e-133	65.7
QAY37432.1\|315376_316636_+	hypothetical protein	NA	NA	NA	NA
QAY36843.1\|316715_317624_-	LysR family transcriptional regulator	NA	NA	NA	NA
QAY36844.1\|317799_318690_-	DMT family transporter	NA	NA	NA	NA
QAY36845.1\|318881_319427_-	exonuclease domain-containing protein	NA	NA	NA	NA
QAY36846.1\|319548_319944_-	short-chain dehydrogenase	NA	NA	NA	NA
QAY36847.1\|320099_320894_+	AraC family transcriptional regulator	NA	NA	NA	NA
QAY36848.1\|321104_323375_-	phospholipase	A0A2H4UUE4	Bodo_saltans_virus	5.7e-09	28.9
QAY36849.1\|323477_325478_-	DUF3346 domain-containing protein	NA	NA	NA	NA
QAY36850.1\|326653_327868_+	ParA family protein	Q1MVJ3	Enterobacteria_phage	3.3e-32	29.4
QAY36851.1\|327871_328846_+	ParB/RepB/Spo0J family partition protein	Q7Y3Y7	Yersinia_phage	6.2e-21	30.1
QAY36852.1\|328966_331084_+\|tRNA	tRNA(Met) cytidine acetyltransferase	NA	NA	NA	NA
QAY36853.1\|331067_331814_+	phosphatase	NA	NA	NA	NA
QAY36854.1\|332728_334654_-	GGDEF domain-containing protein	NA	NA	NA	NA
QAY36855.1\|334894_335533_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
QAY37433.1\|335554_336238_-	helix-turn-helix transcriptional regulator	A2I306	Vibrio_virus	2.0e-34	37.3
QAY36856.1\|336757_337969_-	hypothetical protein	NA	NA	NA	NA
QAY36857.1\|338355_339123_+	AraC family transcriptional regulator	NA	NA	NA	NA
QAY36858.1\|339412_342556_+	bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA	NA	NA	NA	NA
QAY36859.1\|342558_343221_+	hypothetical protein	NA	NA	NA	NA
QAY37434.1\|343389_344886_+	sodium/proline symporter PutP	NA	NA	NA	NA
QAY36860.1\|344947_346273_-	HlyC/CorC family transporter	NA	NA	NA	NA
QAY36861.1\|346403_347462_-	succinylglutamate desuccinylase/aspartoacylase family protein	NA	NA	NA	NA
QAY36862.1\|347805_349146_-	peptidase M23	G9BW84	Planktothrix_phage	1.4e-18	41.3
QAY36863.1\|349412_349850_+	riboflavin-specific deaminase	A0A1V0SE20	Indivirus	7.8e-24	43.8
QAY36864.1\|349971_353910_-	AsmA family protein	NA	NA	NA	NA
QAY36865.1\|355362_356127_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	1.4e-36	40.2
QAY36866.1\|356498_357896_+	c-type cytochrome	NA	NA	NA	NA
QAY36867.1\|357955_358285_-	sulfur reduction protein DsrE	NA	NA	NA	NA
QAY36868.1\|359661_360576_+	hypothetical protein	NA	NA	NA	NA
QAY36869.1\|360952_361279_+	hypothetical protein	NA	NA	NA	NA
QAY36870.1\|361564_363364_-	ATP-binding protein	NA	NA	NA	NA
QAY36871.1\|363364_364558_-	hypothetical protein	NA	NA	NA	NA
QAY36872.1\|364766_365336_-	SLATT domain-containing protein	NA	NA	NA	NA
QAY36873.1\|367230_369732_-	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	3.9e-19	33.7
QAY36874.1\|369755_370073_-	PTS fructose transporter subunit IIB	NA	NA	NA	NA
QAY36875.1\|370463_371051_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
QAY36876.1\|371434_373948_+	glycoside hydrolase family 92 protein	NA	NA	NA	NA
QAY37435.1\|374097_376815_+	glycoside hydrolase family 92 protein	NA	NA	NA	NA
QAY36877.1\|377343_377853_+	N-acetyltransferase	NA	NA	NA	NA
QAY36878.1\|378232_379264_-\|transposase	IS630 family transposase	NA	NA	NA	NA
QAY36879.1\|382470_383267_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	1.4e-31	37.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. CP035459

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. CP035460

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP035460_1	1.1\|13979\|31\|CP035460\|PILER-CR	13979-14009	31	NZ_CP021153	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence	10335-10365	0	1.0
CP035460_1	1.1\|13979\|31\|CP035460\|PILER-CR	13979-14009	31	NZ_CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	13979-14009	0	1.0
CP035460_1	1.2\|14030\|45\|CP035460\|PILER-CR	14030-14074	45	NZ_CP021153	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence	10386-10430	0	1.0
CP035460_1	1.2\|14030\|45\|CP035460\|PILER-CR	14030-14074	45	NZ_CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	14030-14074	0	1.0
CP035460_1	1.3\|14095\|33\|CP035460\|PILER-CR	14095-14127	33	NZ_CP021153	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence	10451-10483	0	1.0
CP035460_1	1.3\|14095\|33\|CP035460\|PILER-CR	14095-14127	33	NZ_CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	14095-14127	0	1.0
CP035460_1	1.4\|14148\|44\|CP035460\|PILER-CR	14148-14191	44	NZ_CP021153	Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence	10504-10547	0	1.0
CP035460_1	1.4\|14148\|44\|CP035460\|PILER-CR	14148-14191	44	NZ_CP035460	Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence	14148-14191	0	1.0
CP035460_1	1.3\|14095\|33\|CP035460\|PILER-CR	14095-14127	33	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	4393-4425	9	0.727

1. spacer 1.1|13979|31|CP035460|PILER-CR matches to NZ_CP021153 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence) position: , mismatch: 0, identity: 1.0

cataagacagaattagcgcagaataggccag	CRISPR spacer
cataagacagaattagcgcagaataggccag	Protospacer
*******************************

2. spacer 1.1|13979|31|CP035460|PILER-CR matches to NZ_CP035460 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence) position: , mismatch: 0, identity: 1.0

cataagacagaattagcgcagaataggccag	CRISPR spacer
cataagacagaattagcgcagaataggccag	Protospacer
*******************************

3. spacer 1.2|14030|45|CP035460|PILER-CR matches to NZ_CP021153 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence) position: , mismatch: 0, identity: 1.0

cgataccagccttaaaagcagcaaagtgtattctaattgggttat	CRISPR spacer
cgataccagccttaaaagcagcaaagtgtattctaattgggttat	Protospacer
*********************************************

4. spacer 1.2|14030|45|CP035460|PILER-CR matches to NZ_CP035460 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence) position: , mismatch: 0, identity: 1.0

cgataccagccttaaaagcagcaaagtgtattctaattgggttat	CRISPR spacer
cgataccagccttaaaagcagcaaagtgtattctaattgggttat	Protospacer
*********************************************

5. spacer 1.3|14095|33|CP035460|PILER-CR matches to NZ_CP021153 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence) position: , mismatch: 0, identity: 1.0

gttaataggaaaaacaagggaagatagacgaca	CRISPR spacer
gttaataggaaaaacaagggaagatagacgaca	Protospacer
*********************************

6. spacer 1.3|14095|33|CP035460|PILER-CR matches to NZ_CP035460 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence) position: , mismatch: 0, identity: 1.0

gttaataggaaaaacaagggaagatagacgaca	CRISPR spacer
gttaataggaaaaacaagggaagatagacgaca	Protospacer
*********************************

7. spacer 1.4|14148|44|CP035460|PILER-CR matches to NZ_CP021153 (Photobacterium damselae subsp. damselae strain KC-Na-1 plasmid pPDD-Na-1-1, complete sequence) position: , mismatch: 0, identity: 1.0

ataaaaccgtgatatacgtcacaatggtgtcctaattgggttgt	CRISPR spacer
ataaaaccgtgatatacgtcacaatggtgtcctaattgggttgt	Protospacer
********************************************

8. spacer 1.4|14148|44|CP035460|PILER-CR matches to NZ_CP035460 (Photobacterium damselae subsp. damselae strain KC-Na-NB1 plasmid pFPPDNB1-2, complete sequence) position: , mismatch: 0, identity: 1.0

ataaaaccgtgatatacgtcacaatggtgtcctaattgggttgt	CRISPR spacer
ataaaaccgtgatatacgtcacaatggtgtcctaattgggttgt	Protospacer
********************************************

9. spacer 1.3|14095|33|CP035460|PILER-CR matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 9, identity: 0.727

gttaataggaaaaacaagggaagatagacgaca	CRISPR spacer
actattaggaaaaactagggaagatatagaaat	Protospacer
..** ********** ********** * .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 15113

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37550.1\|304_946_+	resolvase	NA	NA	NA	NA
QAY37551.1\|2365_2794_-	hypothetical protein	NA	NA	NA	NA
QAY37552.1\|3464_4400_-	DUF535 domain-containing protein	NA	NA	NA	NA
QAY37598.1\|5374_5590_-	DNA-binding protein	NA	NA	NA	NA
QAY37553.1\|5865_7455_+	amino acid permease	NA	NA	NA	NA
QAY37554.1\|7552_8911_+	phosphatidylserine decarboxylase family protein	NA	NA	NA	NA
QAY37555.1\|8989_9415_+	diguanylate cyclase	NA	NA	NA	NA
QAY37556.1\|9485_9764_+	hypothetical protein	NA	NA	NA	NA
QAY37557.1\|10344_11448_+	Fic family protein	NA	NA	NA	NA
QAY37558.1\|12376_12697_-	hypothetical protein	NA	NA	NA	NA
QAY37559.1\|12715_13492_-	ParA family protein	A0A2H4JGZ2	uncultured_Caudovirales_phage	2.2e-13	28.5
QAY37560.1\|14240_15113_-	replication protein RepA	A0A1B0VDL5	Salmonella_phage	4.1e-40	37.5

DBSCAN-SWA_2

19047 : 19494

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37563.1\|19047_19494_+	hypothetical protein	A0A0S1WF56	Vibrio_phage	3.0e-15	36.4

DBSCAN-SWA_3

23518 : 24295

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37568.1\|23518_24295_-	ParA family protein	A0A2H4JGZ2	uncultured_Caudovirales_phage	2.2e-13	28.5

DBSCAN-SWA_4

35469 : 37700

Escherichia_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37572.1\|35469_35853_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	4.2e-05	35.1
QAY37573.1\|35911_36955_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.5e-73	42.6
QAY37574.1\|36941_37700_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-75	62.0

DBSCAN-SWA_5

41881 : 43081

Morganella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37577.1\|41881_42094_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	4.4e-17	61.4
QAY37578.1\|42319_42529_-	hypothetical protein	NA	NA	NA	NA
QAY37579.1\|42868_43081_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	4.3e-20	68.6

DBSCAN-SWA_6

49816 : 51605

Escherichia_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAY37585.1\|49816_50575_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-75	62.0
QAY37586.1\|50561_51605_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.5e-73	42.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage