CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP031638	Streptococcus pyogenes strain MGAS8347 chromosome, complete genome	3 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csn2,cas9,csm6,DinG,csa3	0	6	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP031638_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031638_1

646379-646474

TypeI

I-C

Consensus_repeat	Method
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	CRISPRCasFinder

1 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of CP031638_1

>merge|CP031638|1|646379-646474|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAATTTCATGAGCTTCTTTACTCTCAAAGTAAGAGTGGTCTCACCCTTCATGGGTGAGTGGATTGAAA

>CP031638|1|1|646379-646474|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TTTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP031638.1\|QBB25620.1\|651760_652840_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
CP031638.1\|QBB25621.1\|652853_653570_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225917
CP031638.1\|QBB25610.1\|641479_643375_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|273839
CP031638.1\|QBB25619.1\|649954_651688_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
CP031638.1\|QBB25615.1\|646634_647345_+\|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl\|CDD\|223856
CP031638.1\|QBB25617.1\|648023_649130_+\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|184456
CP031638.1\|QBB25609.1\|640751_641480_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
CP031638.1\|QBB25623.1\|654350_655031_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
CP031638.1\|QBB25612.1\|644229_644904_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
CP031638.1\|QBB25622.1\|653735_654209_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
CP031638.1\|QBB25616.1\|647357_647981_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
CP031638.1\|QBB25607.1\|635408_638057_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP031638.1\|QBB25614.1\|645936_646230_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
CP031638.1\|QBB25608.1\|638210_640619_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP031638.1\|QBB25624.1\|655304_656540_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
CP031638.1\|QBB25618.1\|649217_649958_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|227095
CP031638.1\|QBB25613.1\|644900_645926_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
CP031638.1\|QBB25605.1\|634667_634847_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
CP031638.1\|QBB25606.1\|634843_635407_+\|shikimate-kinase	unknown	unknown	unknown
CP031638.1\|QBB25611.1\|643379_644228_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175

Protein	Function_ID	Function_description	E-value
CP031638.1\|QBB25620.1\|651760_652840_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.18444e-35
CP031638.1\|QBB25621.1\|652853_653570_+\|hypothetical-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	8.83652e-106
CP031638.1\|QBB25610.1\|641479_643375_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
CP031638.1\|QBB25619.1\|649954_651688_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.03945e-65
CP031638.1\|QBB25615.1\|646634_647345_+\|cytochrome-c-biogenesis-protein-CcdA	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	2.85986e-42
CP031638.1\|QBB25617.1\|648023_649130_+\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	3.04644e-163
CP031638.1\|QBB25609.1\|640751_641480_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.32713e-117
CP031638.1\|QBB25623.1\|654350_655031_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
CP031638.1\|QBB25612.1\|644229_644904_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	3.0744e-43
CP031638.1\|QBB25622.1\|653735_654209_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.23847e-66
CP031638.1\|QBB25607.1\|635408_638057_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
CP031638.1\|QBB25614.1\|645936_646230_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
CP031638.1\|QBB25608.1\|638210_640619_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.76387e-159
CP031638.1\|QBB25624.1\|655304_656540_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
CP031638.1\|QBB25618.1\|649217_649958_+\|DNA-binding-response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	6.22184e-83
CP031638.1\|QBB25613.1\|644900_645926_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
CP031638.1\|QBB25605.1\|634667_634847_+\|N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	3.61304e-12
CP031638.1\|QBB25616.1\|647357_647981_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.08316e-34
CP031638.1\|QBB25611.1\|643379_644228_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	2.68212e-160

>CP031638.1|QBB25614.1|645936_646230_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>CP031638.1|QBB25613.1|644900_645926_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>CP031638.1|QBB25612.1|644229_644904_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>CP031638.1|QBB25611.1|643379_644228_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>CP031638.1|QBB25610.1|641479_643375_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMLKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>CP031638.1|QBB25609.1|640751_641480_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>CP031638.1|QBB25608.1|638210_640619_+|CRISPR-associated-helicase/endonuclease-Cas3
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>CP031638.1|QBB25607.1|635408_638057_+|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIVRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQAKYDATQERIAEMKKIKS
>CP031638.1|QBB25606.1|634843_635407_+|shikimate-kinase
MNLIIIGAQASGKMTIEQEVARQTGMNLFHNHDSIDFVLRFMPWSQESTALIERMRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>CP031638.1|QBB25605.1|634667_634847_+|N-acetyltransferase
MHKIELGCYDYNKQSQAVARKLGFTLEANVRERKDVQGRRCGGMRFGLLRSEWEEQKQK
>CP031638.1|QBB25615.1|646634_647345_+|cytochrome-c-biogenesis-protein-CcdA
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHIFLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>CP031638.1|QBB25616.1|647357_647981_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMVKKEITQDKMSMAVKKKDKMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>CP031638.1|QBB25617.1|648023_649130_+|peptide-methionine-(R)-S-oxide-reductase
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>CP031638.1|QBB25618.1|649217_649958_+|DNA-binding-response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>CP031638.1|QBB25619.1|649954_651688_+|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTNLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMHELMADDTQENE
>CP031638.1|QBB25620.1|651760_652840_+|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVEGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETNIPNEGYRKNPNIDKLMRLRKRQQYKDGLLSFDLMKKHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>CP031638.1|QBB25621.1|652853_653570_+|hypothetical-protein
MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHAITSVHVLDKDNPHVPLFTEN
>CP031638.1|QBB25622.1|653735_654209_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>CP031638.1|QBB25623.1|654350_655031_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>CP031638.1|QBB25624.1|655304_656540_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Crispr_ID: CP031638_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031638_2

1052322-1052621

TypeII

II-A

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	PILER-CR

4 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP031638_2

>merge|CP031638|2|1052322-1052621|CRISPRCasFinder,CRT,PILER-CR
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAACGGAAAGCAGGAGAAAGGACGTTAATATGTCGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACGTCAAACTCAATTTTTTGTCTAGCTCTATTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAGACAAAAGAAAAAGCATTGTCAATTTCTAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAATAATCAGTTTAAAAATCCATCTGGAGCAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031638|2|2|1052322-1052621|CRISPRCasFinder
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAAC	GGAAAGCAGGAGAAAGGACGTTAATATGTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031638|2|1|1052322-1052621|CRT
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAAC	GGAAAGCAGGAGAAAGGACGTTAATATGTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031638|2|1|1052388-1052621|PILER-CR
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP031638.1\|QBB25980.1\|1045694_1046714_-\|putative-sulfate-exporter-family-transporter	unknown	unknown	gnl\|CDD\|225411
CP031638.1\|QBB25987.1\|1053375_1053717_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP031638.1\|QBB25993.1\|1061291_1062422_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP031638.1\|QBB25986.1\|1052723_1053386_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP031638.1\|QBB25992.1\|1060529_1061282_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
CP031638.1\|QBB25988.1\|1053713_1054583_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP031638.1\|QBB25982.1\|1047466_1048852_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
CP031638.1\|QBB25990.1\|1059133_1059766_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
CP031638.1\|QBB25977.1\|1043726_1044536_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
CP031638.1\|QBB25995.1\|1063249_1064605_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
CP031638.1\|QBB25994.1\|1062484_1063126_-\|hypothetical-protein	unknown	unknown	unknown
CP031638.1\|QBB25979.1\|1045062_1045488_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
CP031638.1\|QBB25991.1\|1059765_1060530_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
CP031638.1\|QBB25984.1\|1050930_1051035_-\|exfoliative-toxin	unknown	unknown	unknown
CP031638.1\|QBB25989.1\|1054582_1058689_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP031638.1\|QBB25981.1\|1046843_1047281_-\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692
CP031638.1\|QBB25985.1\|1051039_1052173_-\|ISAs1-like-element-IS1548-family-transposase	unknown	unknown	gnl\|CDD\|227720
CP031638.1\|QBB25983.1\|1049038_1050871_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP031638.1\|QBB25978.1\|1044552_1045044_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
CP031638.1\|QBB25976.1\|1042902_1043730_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239

Protein	Function_ID	Function_description	E-value
CP031638.1\|QBB25980.1\|1045694_1046714_-\|putative-sulfate-exporter-family-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	3.12379e-103
CP031638.1\|QBB25987.1\|1053375_1053717_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.79e-58
CP031638.1\|QBB25993.1\|1061291_1062422_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP031638.1\|QBB25986.1\|1052723_1053386_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.6851e-120
CP031638.1\|QBB25992.1\|1060529_1061282_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.21279e-109
CP031638.1\|QBB25988.1\|1053713_1054583_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.48912e-131
CP031638.1\|QBB25982.1\|1047466_1048852_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	3.32595e-11
CP031638.1\|QBB25990.1\|1059133_1059766_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.04206e-87
CP031638.1\|QBB25977.1\|1043726_1044536_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
CP031638.1\|QBB25995.1\|1063249_1064605_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP031638.1\|QBB25979.1\|1045062_1045488_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	1.16501e-30
CP031638.1\|QBB25991.1\|1059765_1060530_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.84127e-128
CP031638.1\|QBB25989.1\|1054582_1058689_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP031638.1\|QBB25981.1\|1046843_1047281_-\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	5.00558e-84
CP031638.1\|QBB25985.1\|1051039_1052173_-\|ISAs1-like-element-IS1548-family-transposase	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	1.42629e-30
CP031638.1\|QBB25983.1\|1049038_1050871_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP031638.1\|QBB25978.1\|1044552_1045044_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
CP031638.1\|QBB25976.1\|1042902_1043730_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109

>CP031638.1|QBB25985.1|1051039_1052173_-|ISAs1-like-element-IS1548-family-transposase
MIDFIISIDDCAVELDSRQSWKIGYPLSTILFLVFVCQLAGIETWKEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQSLTSLDAVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNFIRKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG
>CP031638.1|QBB25984.1|1050930_1051035_-|exfoliative-toxin
MIDLKRNLFKIDVRAQKDEEKVFMRTAWIIRKKR
>CP031638.1|QBB25983.1|1049038_1050871_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
>CP031638.1|QBB25982.1|1047466_1048852_-|LPXTG-cell-wall-anchor-domain-containing-protein
MNKTKQNKTKQNKTKQNKTKQNKTKTKHSLLCRYGLTSAAALLLTFGGASAVKADEQEEKAKVRTELIQELAQGLGGIEKKNFPTLGDEDLDHTYMTKLLTYLQEREQAENSWRKRLLKGIQDHALDGQDGRNGERGEQGPTGPTGPAGPRGLQGLQGERGEQGPTGPAGPRGLQGERGEQGPTGLAGKAGEAGAKGETGPAGPQGPRGEQGPQGLPGKDGEAGAQGPAGPMGPAGERGEKGEPGTQGAKGDRGETGPVGPRGERGEAGPAGKDGERGPVGPAGKDGQNGQDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>CP031638.1|QBB25981.1|1046843_1047281_-|peptide-methionine-(R)-S-oxide-reductase
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET
>CP031638.1|QBB25980.1|1045694_1046714_-|putative-sulfate-exporter-family-transporter
MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNDGFATFAGTAVNDTSSVTATATAWDALHHSNTLDDATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVSADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>CP031638.1|QBB25979.1|1045062_1045488_-|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDNFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD
>CP031638.1|QBB25978.1|1044552_1045044_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>CP031638.1|QBB25977.1|1043726_1044536_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>CP031638.1|QBB25976.1|1042902_1043730_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>CP031638.1|QBB25986.1|1052723_1053386_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSELKFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>CP031638.1|QBB25987.1|1053375_1053717_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>CP031638.1|QBB25988.1|1053713_1054583_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVKSQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTLFGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKALNNEGKGVPEFRI
>CP031638.1|QBB25989.1|1054582_1058689_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRLNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKVLTRSDKNRGKSNNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIVKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATFIHQSITGLYETRIDLSQLGGD
>CP031638.1|QBB25990.1|1059133_1059766_-|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>CP031638.1|QBB25991.1|1059765_1060530_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>CP031638.1|QBB25992.1|1060529_1061282_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGGLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKPHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>CP031638.1|QBB25993.1|1061291_1062422_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>CP031638.1|QBB25994.1|1062484_1063126_-|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQENLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSRP
>CP031638.1|QBB25995.1|1063249_1064605_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

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Crispr_ID: CP031638_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031638_3

1791787-1791883

Orphan

Consensus_repeat	Method
AAAAACCCAATTTTTTTTCGTCTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP031638_3

>merge|CP031638|3|1791787-1791883|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTATTTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGTCAAGATAAAAATCCAATTTTTTTTCGTCTTAT

>CP031638|3|3|1791787-1791883|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTAT	TTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGTCAAGAT
AAAAATCCAATTTTTTTTCGTCTTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP031638.1\|QBB26648.1\|1790298_1790481_-\|hypothetical-protein	unknown	unknown	unknown
CP031638.1\|QBB26646.1\|1789486_1789855_-\|hypothetical-protein	unknown	unknown	unknown
CP031638.1\|QBB26652.1\|1791939_1792383_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031638.1\|QBB26647.1\|1789954_1790287_-\|hypothetical-protein	unknown	unknown	unknown
CP031638.1\|QBB26656.1\|1795512_1796880_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|180232
CP031638.1\|QBB26643.1\|1786892_1787066_-\|DUF2758-domain-containing-protein	unknown	unknown	unknown
CP031638.1\|QBB26651.1\|1791582_1791771_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031638.1\|QBB26645.1\|1788955_1789477_-\|hypothetical-protein	unknown	unknown	unknown
CP031638.1\|QBB26650.1\|1791000_1791567_-\|phage-repressor-protein	unknown	unknown	gnl\|CDD\|226144
CP031638.1\|QBB26653.1\|1792562_1793726_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP031638.1\|QBB26644.1\|1787352_1788966_-\|phage-resistance-protein	unknown	unknown	unknown
CP031638.1\|QBB26660.1\|1801446_1801764_-\|phosphohydrolase	unknown	unknown	gnl\|CDD\|240044
CP031638.1\|QBB26657.1\|1796909_1797362_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
CP031638.1\|QBB26655.1\|1795223_1795496_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226872
CP031638.1\|QBB26654.1\|1793882_1794494_-\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
CP031638.1\|QBB26649.1\|1790701_1790971_-\|phage-antirepressor-protein	unknown	unknown	unknown
CP031638.1\|QBB26751.1\|1789763_1789955_-\|hypothetical-protein	unknown	unknown	unknown
CP031638.1\|QBB26659.1\|1799424_1801323_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
CP031638.1\|QBB26658.1\|1797358_1799335_-\|DHH-family-phosphoesterase	unknown	unknown	gnl\|CDD\|226404
CP031638.1\|QBB26661.1\|1802539_1803661_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664

Protein	Function_ID	Function_description	E-value
CP031638.1\|QBB26653.1\|1792562_1793726_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.50808e-45
CP031638.1\|QBB26652.1\|1791939_1792383_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.81587e-06
CP031638.1\|QBB26651.1\|1791582_1791771_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00222954
CP031638.1\|QBB26650.1\|1791000_1791567_-\|phage-repressor-protein	gnl\|CDD\|226144	COG3617, COG3617, Prophage antirepressor [Transcription].	1.58213e-27
CP031638.1\|QBB26660.1\|1801446_1801764_-\|phosphohydrolase	gnl\|CDD\|240044	cd04688, Nudix_Hydrolase_29, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	7.82374e-17
CP031638.1\|QBB26657.1\|1796909_1797362_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	1.02239e-55
CP031638.1\|QBB26655.1\|1795223_1795496_-\|hypothetical-protein	gnl\|CDD\|226872	COG4466, Veg, Uncharacterized protein conserved in bacteria [Function unknown].	7.52485e-33
CP031638.1\|QBB26654.1\|1793882_1794494_-\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	8.00838e-118
CP031638.1\|QBB26656.1\|1795512_1796880_-\|replicative-DNA-helicase	gnl\|CDD\|180232	PRK05748, PRK05748, replicative DNA helicase; Provisional.	0
CP031638.1\|QBB26659.1\|1799424_1801323_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
CP031638.1\|QBB26658.1\|1797358_1799335_-\|DHH-family-phosphoesterase	gnl\|CDD\|226404	COG3887, COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms].	0
CP031638.1\|QBB26661.1\|1802539_1803661_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0

>CP031638.1|QBB26651.1|1791582_1791771_-|XRE-family-transcriptional-regulator
MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNYKAPKRIYASVMEWLAEDY
>CP031638.1|QBB26650.1|1791000_1791567_-|phage-repressor-protein
MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRARDVAEMIDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEHGLYEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDIDDLSYIKQKLTDLQDVDSLQDLRWKMAKLYHVIETLDEY
>CP031638.1|QBB26649.1|1790701_1790971_-|phage-antirepressor-protein
MRTDKGEMIMKATTYKELKKWIDEGVDLAELAQGYADKVPSVDREQFEAVTQGIFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY
>CP031638.1|QBB26648.1|1790298_1790481_-|hypothetical-protein
MTSVRTAQLLNNGLGLVGQDLKDVLSALANSVNPSIEKQISHIMIDRANTGEWLANVGKK
>CP031638.1|QBB26647.1|1789954_1790287_-|hypothetical-protein
MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQHIAWVIIANVMTEYVNKFRKSATSFEKAWDALGYQQTTEIVFRAVNGLPCSEKDTGELETYLSEVSA
>CP031638.1|QBB26751.1|1789763_1789955_-|hypothetical-protein
MQELNLTPTQTLILFIVLGLVGLLLSLSKPLIEIDLPEDTQVPKPPQNANYGAYIQSQNHYYN
>CP031638.1|QBB26646.1|1789486_1789855_-|hypothetical-protein
MTYQKIPKYLNHLRTQTMGLIFNHRTIITIRREQMQLLSREAELELLEKVGCYLEKRWQLELENKDDWDLIPRQDLLEKLDITGTTLKNWEKEGLKSYQSPFENSKKVYYRKSDIYNFLSVD
>CP031638.1|QBB26645.1|1788955_1789477_-|hypothetical-protein
MDYLEVTMTKDCVKIFNFLYKYPTKAYQKDEYFKLLYMHPLDSFLTSFSLSGIRVKVTDKPVLAGWKLVRDIEVRIATGELLEMIEELEICYLRKHQTVSYVEIKFYVVHLLTYGIRSRYDMQFFTKLLFCCGYDQETVIGIYSNITKNTRLSRDFITLQAKLYQTKKGTHEH
>CP031638.1|QBB26644.1|1787352_1788966_-|phage-resistance-protein
MSIKENIDKLVSMEWTESIFGQSKMKADYKRQLSKVIELDTLSNIHHNGETYAVSNQEVMYLSESKGRTHKFISGNVKTKSKGKGRDSQKYLVVSFDHQFPPFAKLVVDYLLGRFTFFNNKLYDVNNRQAQVLDDFTIQSLYGFKKDNPFILEILEGIHQTLNIRPAKQLEAYKISGRDFIIDLKEHRLYRTNPSSDSSFFKFYDVDYHTAIGSKKKVGKFLDYVIADHDSLHNATLQAYYIAQVACGLKSKQNFFISKSGVRTGKGLRHIGLSGIFNKIDVELDLLIKGGFEASNAWGAFAGGEMALATEQGDIVGDKMERVLKIIATEKTHMARSIGGNLGTVNLTSVLCIDTNRTVALSDEMNGRAVLIQYQNRPEGETDLEREKAFEEYWQTFTEMDKSPKIEGVIGFLLVSLDYFRKNDMKFDWRAVEVVNDDDLDDFQVYLINHLSEKDFVERDSYVRELYNSTYGKNNNQAGQRMRTIGVKSYRKQTTGGRKIPGYKVDNIKRFNKFSGGEKENTNIFDMFEKLNQPLPP
>CP031638.1|QBB26643.1|1786892_1787066_-|DUF2758-domain-containing-protein
MKIKLFYQKHNESLDDFEYRVNQFTLSVSVIDIKLSEATYGNYEDMSTTTSLLVLYR
>CP031638.1|QBB26652.1|1791939_1792383_+|XRE-family-transcriptional-regulator
MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENPKNTIKPDKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFSFDMTATESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP
>CP031638.1|QBB26653.1|1792562_1793726_+|site-specific-integrase
MNIKEYKKKNGTIIYRTSVYLGVDQVTGKKARTTITASTKKGVKIKARDALNNFAMNGYTVKEKPTVTTYKELTALWWESYKNTIKPNSRQSMEGIVRLHILPAFGDCKLSKLTTPVIQQQVNKWANNANKGIKGAYANYSFLNNINRRILQYGVTMQVIEHNPARDVIIPRKQNNKEHKVKFFSNQELKQFLNYLDDLDLSSYENFFDYVLYKTLLATGCRIGEVLALEWSDIDLKKGTIKVSKTLNRYQETNTPKSKAGLRDIEIDRATVLLLKQYKNRQQVLSWDLGRSETIVFTPFTTKYAYACLLRKRLQKHFKAAGVPDISFHGFRHTHATIMLYAGIEAKDLQYRLGHSNISMTLNTYVHATKEGAKKAVSIFETAISNL
>CP031638.1|QBB26654.1|1793882_1794494_-|30S-ribosomal-protein-S4
MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
>CP031638.1|QBB26655.1|1795223_1795496_-|hypothetical-protein
MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRLIEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD
>CP031638.1|QBB26656.1|1795512_1796880_-|replicative-DNA-helicase
MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER
>CP031638.1|QBB26657.1|1796909_1797362_-|50S-ribosomal-protein-L9
MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLTITEA
>CP031638.1|QBB26658.1|1797358_1799335_-|DHH-family-phosphoesterase
MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLLFVVALLWYQKEAYHLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNPYAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSFVGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFYRRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQIGQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDRIKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDFPDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTSRTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLYSNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFNLAACQLTDISLPQAKHLLLKTINMTMKETGEVES
>CP031638.1|QBB26659.1|1799424_1801323_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
>CP031638.1|QBB26660.1|1801446_1801764_-|phosphohydrolase
MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVGIRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSINWIK
>CP031638.1|QBB26661.1|1802539_1803661_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448767	Streptococcus phage Javan467, complete genome	17890-17919	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448685	Streptococcus phage Javan155, complete genome	18198-18227	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448771	Streptococcus phage Javan481, complete genome	17415-17444	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448829	Streptococcus phage Javan7, complete genome	19776-19805	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448736	Streptococcus phage Javan35, complete genome	20259-20288	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448781	Streptococcus phage Javan5, complete genome	22281-22310	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK449012	Streptococcus phage Javan94, complete genome	19127-19156	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	17995-18024	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448969	Streptococcus phage Javan514, complete genome	19138-19167	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MH853355	Streptococcus phage LF1, complete genome	10633-10662	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448964	Streptococcus phage Javan502, complete genome	17719-17748	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448943	Streptococcus phage Javan450, complete genome	17890-17919	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448972	Streptococcus phage Javan520, complete genome	17264-17293	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448938	Streptococcus phage Javan44, complete genome	20260-20289	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448855	Streptococcus phage Javan150, complete genome	18394-18423	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448786	Streptococcus phage Javan509, complete genome	17890-17919	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448774	Streptococcus phage Javan487, complete genome	16251-16280	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448963	Streptococcus phage Javan498, complete genome	13512-13541	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448773	Streptococcus phage Javan485, complete genome	19137-19166	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448911	Streptococcus phage Javan34, complete genome	20259-20288	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448837	Streptococcus phage Javan10, complete genome	18305-18334	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448742	Streptococcus phage Javan37, complete genome	20096-20125	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MH853358	Streptococcus phage LF4, complete genome	10633-10662	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448845	Streptococcus phage Javan118, complete genome	18668-18697	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448916	Streptococcus phage Javan36, complete genome	20259-20288	0	1.0
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448853	Streptococcus phage Javan144, complete genome	18198-18227	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448871	Streptococcus phage Javan196, complete genome	33084-33113	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448697	Streptococcus phage Javan185, complete genome	33084-33113	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448693	Streptococcus phage Javan177, complete genome	33084-33113	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448772	Streptococcus phage Javan483, complete genome	32792-32821	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448696	Streptococcus phage Javan183, complete genome	33084-33113	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	NC_009819	Streptococcus phage P9, complete genome	32033-32062	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448793	Streptococcus phage Javan523, complete genome	33428-33457	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448868	Streptococcus phage Javan188, complete genome	33085-33114	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448866	Streptococcus phage Javan184, complete genome	33084-33113	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448954	Streptococcus phage Javan476, complete genome	31815-31844	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448699	Streptococcus phage Javan189, complete genome	33084-33113	0	1.0
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448867	Streptococcus phage Javan186, complete genome	33084-33113	0	1.0
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448775	Streptococcus phage Javan489, complete genome	25298-25327	0	1.0
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448794	Streptococcus phage Javan525, complete genome	22421-22450	0	1.0
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448953	Streptococcus phage Javan474, complete genome	27019-27048	0	1.0
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448765	Streptococcus phage Javan459, complete genome	22420-22449	0	1.0
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448957	Streptococcus phage Javan484, complete genome	27899-27928	0	1.0
CP031638_2	2.4\|1052556\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052556-1052585	30	MK448662	Streptococcus satellite phage Javan97, complete genome	6081-6110	0	1.0
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448522	Streptococcus satellite phage Javan519, complete genome	1870-1914	0	1.0
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448330	Streptococcus satellite phage Javan136, complete genome	2770-2814	0	1.0
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448328	Streptococcus satellite phage Javan130, complete genome	2770-2814	0	1.0
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448513	Streptococcus satellite phage Javan479, complete genome	1870-1914	0	1.0
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448332	Streptococcus satellite phage Javan142, complete genome	2777-2821	0	1.0
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448331	Streptococcus satellite phage Javan138, complete genome	2777-2821	0	1.0
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448771	Streptococcus phage Javan481, complete genome	6934-6967	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448681	Streptococcus phage Javan141, complete genome	6532-6565	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448944	Streptococcus phage Javan452, complete genome	11198-11231	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448672	Streptococcus phage Javan117, complete genome	6780-6813	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448849	Streptococcus phage Javan128, complete genome	6683-6716	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448774	Streptococcus phage Javan487, complete genome	6919-6952	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448958	Streptococcus phage Javan486, complete genome	9163-9196	1	0.971
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448742	Streptococcus phage Javan37, complete genome	9155-9188	1	0.971
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448946	Streptococcus phage Javan456, complete genome	36512-36541	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448779	Streptococcus phage Javan497, complete genome	31741-31770	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448795	Streptococcus phage Javan527, complete genome	38519-38548	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448944	Streptococcus phage Javan452, complete genome	35553-35582	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448968	Streptococcus phage Javan512, complete genome	31741-31770	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	NC_004584	Streptococcus prophage 315.1, complete genome	31585-31614	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448797	Streptococcus phage Javan531, complete genome	31741-31770	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448978	Streptococcus phage Javan532, complete genome	31479-31508	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448785	Streptococcus phage Javan507, complete genome	31480-31509	1	0.967
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	NC_004589	Streptococcus prophage 315.6, complete genome	31838-31867	1	0.967
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448946	Streptococcus phage Javan456, complete genome	26948-26977	1	0.967
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448333	Streptococcus satellite phage Javan145, complete genome	2769-2813	1	0.978
CP031638_3	3.1\|1791813\|45\|CP031638\|CRISPRCasFinder	1791813-1791857	45	MK448340	Streptococcus satellite phage Javan156, complete genome	2769-2813	1	0.978
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448767	Streptococcus phage Javan467, complete genome	6872-6905	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448973	Streptococcus phage Javan522, complete genome	8839-8872	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448862	Streptococcus phage Javan178, complete genome	6908-6941	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448942	Streptococcus phage Javan448, complete genome	6871-6904	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK449010	Streptococcus phage Javan90, complete genome	9367-9400	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK449012	Streptococcus phage Javan94, complete genome	8201-8234	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	6977-7010	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448969	Streptococcus phage Javan514, complete genome	9627-9660	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448943	Streptococcus phage Javan450, complete genome	6872-6905	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448972	Streptococcus phage Javan520, complete genome	6681-6714	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448786	Streptococcus phage Javan509, complete genome	6872-6905	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448778	Streptococcus phage Javan493, complete genome	8854-8887	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448963	Streptococcus phage Javan498, complete genome	3461-3494	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448773	Streptococcus phage Javan485, complete genome	9627-9660	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448851	Streptococcus phage Javan14, complete genome	12140-12173	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448833	Streptococcus phage Javan87, complete genome	9367-9400	2	0.941
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448673	Streptococcus phage Javan119, complete genome	9946-9979	2	0.941
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448755	Streptococcus phage Javan423, complete genome	19783-19812	2	0.933
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	MK448756	Streptococcus phage Javan425, complete genome	19783-19812	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448771	Streptococcus phage Javan481, complete genome	26991-27020	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448942	Streptococcus phage Javan448, complete genome	18422-18451	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448794	Streptococcus phage Javan525, complete genome	32018-32047	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448964	Streptococcus phage Javan502, complete genome	27279-27308	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	M19348	Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds	511-540	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448951	Streptococcus phage Javan470, complete genome	32170-32199	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448765	Streptococcus phage Javan459, complete genome	32016-32045	2	0.933
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448764	Streptococcus phage Javan457, complete genome	25122-25151	2	0.933
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MK448933	Streptococcus phage Javan420, complete genome	26823-26852	2	0.933
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448964	Streptococcus phage Javan502, complete genome	6851-6884	3	0.912
CP031638_2	2.1\|1052358\|30\|CP031638\|CRISPRCasFinder,CRT	1052358-1052387	30	NC_028666	Streptococcus phage Str-PAP-1, complete genome	24240-24269	3	0.9
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448698	Streptococcus phage Javan187, complete genome	27333-27362	4	0.867
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448845	Streptococcus phage Javan118, complete genome	8661-8694	5	0.853
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448767	Streptococcus phage Javan467, complete genome	27472-27501	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	27577-27606	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448976	Streptococcus phage Javan528, complete genome	32036-32065	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448943	Streptococcus phage Javan450, complete genome	27472-27501	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448972	Streptococcus phage Javan520, complete genome	27647-27676	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448786	Streptococcus phage Javan509, complete genome	27472-27501	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448963	Streptococcus phage Javan498, complete genome	23094-23123	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448773	Streptococcus phage Javan485, complete genome	28601-28630	5	0.833
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MK448950	Streptococcus phage Javan464, complete genome	32684-32713	6	0.8
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	MN693570	Marine virus AFVG_25M8, complete genome	48011-48040	6	0.8
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	NZ_CP014852	Bacillus thuringiensis strain HD12 plasmid pHD120161, complete sequence	135700-135729	7	0.767
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	NC_010895	Bacillus thuringiensis serovar tenebrionis plasmid pBMB175, complete sequence	869-898	7	0.767
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	CP020760	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-21, complete sequence	3892-3921	7	0.767
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	NC_005567	Bacillus thuringiensis H1.1 plasmid pGI3, complete sequence	1823-1852	7	0.767
CP031638_1	1.1\|646410\|34\|CP031638\|CRISPRCasFinder	646410-646443	34	MK448704	Streptococcus phage Javan213, complete genome	8199-8232	8	0.765
CP031638_2	2.2\|1052424\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052424-1052453	30	NC_013792	Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence	63431-63460	8	0.733
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	NZ_CP031836	Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence	84673-84702	8	0.733
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	NZ_CP020458	Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence	86560-86589	8	0.733
CP031638_2	2.4\|1052556\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052556-1052585	30	NC_021559	Prochlorococcus phage P-SSM3 genomic sequence	77011-77040	8	0.733
CP031638_2	2.3\|1052490\|30\|CP031638\|CRISPRCasFinder,CRT,PILER-CR	1052490-1052519	30	MN694808	Marine virus AFVG_250M14, complete genome	476-505	9	0.7

1. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

2. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

3. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

4. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448829 (Streptococcus phage Javan7, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

5. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

6. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

7. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

8. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

9. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

10. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MH853355 (Streptococcus phage LF1, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

11. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

12. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

13. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

14. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

15. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

16. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

17. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

18. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

19. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

20. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

21. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

22. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

23. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MH853358 (Streptococcus phage LF4, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

24. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

25. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

26. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

27. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

28. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

29. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

30. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

31. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

32. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

33. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

34. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

35. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

36. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

37. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

38. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

39. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

40. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

41. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

42. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

43. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

44. spacer 2.4|1052556|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448662 (Streptococcus satellite phage Javan97, complete genome) position: , mismatch: 0, identity: 1.0

aataatcagtttaaaaatccatctggagca	CRISPR spacer
aataatcagtttaaaaatccatctggagca	Protospacer
******************************

45. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448522 (Streptococcus satellite phage Javan519, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

46. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448330 (Streptococcus satellite phage Javan136, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

47. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448328 (Streptococcus satellite phage Javan130, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

48. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448513 (Streptococcus satellite phage Javan479, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

49. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448332 (Streptococcus satellite phage Javan142, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

50. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448331 (Streptococcus satellite phage Javan138, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

51. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

52. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

53. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

54. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

55. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

56. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

57. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

58. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 1, identity: 0.971

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttctttactctcaaagtaagagtg	Protospacer
.*********************************

59. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtttagctctatt	Protospacer
*******************.**********

60. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

61. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

62. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

63. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

64. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

65. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

66. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

67. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

68. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

69. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.967

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttctg	Protospacer
*****************************.

70. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448333 (Streptococcus satellite phage Javan145, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
**************************************.******

71. spacer 3.1|1791813|45|CP031638|CRISPRCasFinder matches to MK448340 (Streptococcus satellite phage Javan156, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
**************************************.******

72. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

73. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

74. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagctgctttactctcaaagtaagagtg	Protospacer
.********** **********************

75. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

76. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

77. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

78. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

79. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagctgctttactctcaaagtaagagtg	Protospacer
.********** **********************

80. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

81. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagctgctttactctcaaagtaagagtg	Protospacer
.********** **********************

82. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

83. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

84. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

85. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagctgctttactctcaaagtaagagtg	Protospacer
.********** **********************

86. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagctgctttactctcaaagtaagagtg	Protospacer
.********** **********************

87. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttactctcaaagtaagagtg	Protospacer
.***********.*********************

88. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.941

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagctgctttactctcaaagtaagagtg	Protospacer
.********** **********************

89. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448755 (Streptococcus phage Javan423, complete genome) position: , mismatch: 2, identity: 0.933

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttatcatgtc	Protospacer
*********************** .*****

90. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to MK448756 (Streptococcus phage Javan425, complete genome) position: , mismatch: 2, identity: 0.933

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttatcatgtc	Protospacer
*********************** .*****

91. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

92. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

93. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

94. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

95. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to M19348 (Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

96. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaattcaattttttgtttagctctatt	Protospacer
******.************.**********

97. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

98. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

99. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 2, identity: 0.933

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatctctg	Protospacer
*************************.***.

100. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 3, identity: 0.912

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
cttcatgagcttttttaccctcaaagtaagagtg	Protospacer
.***********.*****.***************

101. spacer 2.1|1052358|30|CP031638|CRISPRCasFinder,CRT matches to NC_028666 (Streptococcus phage Str-PAP-1, complete genome) position: , mismatch: 3, identity: 0.9

ggaaagcaggagaaaggacgttaatatgtc-	CRISPR spacer
gcaaagcaggagaaaggacgtt-acatgtca	Protospacer
* ******************** *.*****

102. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 4, identity: 0.867

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctttgca	Protospacer
*************************.*..

103. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 5, identity: 0.853

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
tggaataagctgctttactctcaaagtaagagtg	Protospacer
*   **.**** **********************

104. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

105. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

106. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448976 (Streptococcus phage Javan528, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

107. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

108. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

109. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

110. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

111. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

112. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 6, identity: 0.8

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttccgtctagctttgca	Protospacer
***************..********.*..

113. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MN693570 (Marine virus AFVG_25M8, complete genome) position: , mismatch: 6, identity: 0.8

gtcaaactcaattttttgtctagc-tctatt	CRISPR spacer
attaaactcaattttttgactagcatgtaa-	Protospacer
.*.*************** ***** * **

114. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014852 (Bacillus thuringiensis strain HD12 plasmid pHD120161, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
caccagaagcaaaagcattgtcaatttccg	Protospacer
 . **.*** ******************..

115. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_010895 (Bacillus thuringiensis serovar tenebrionis plasmid pBMB175, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttact	Protospacer
*.* *********** ***.******* .

116. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to CP020760 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-21, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttacc	Protospacer
*.* *********** ***.******* .

117. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_005567 (Bacillus thuringiensis H1.1 plasmid pGI3, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttacc	Protospacer
*.* *********** ***.******* .

118. spacer 1.1|646410|34|CP031638|CRISPRCasFinder matches to MK448704 (Streptococcus phage Javan213, complete genome) position: , mismatch: 8, identity: 0.765

tttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttgcatgagcttctttgctctcaaatgcgctgtg	Protospacer
** *************.********   .  ***

119. spacer 2.2|1052424|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_013792 (Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence) position: , mismatch: 8, identity: 0.733

---gtcaaactcaattttttgtctagctctatt	CRISPR spacer
ccttttga---taatttcttgtctagctctatt	Protospacer
    *..*   .*****.***************

120. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031836 (Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
taaaaaaagaaaaagcatcgtcaattagac	Protospacer
 .* **************.*******

121. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020458 (Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence) position: , mismatch: 8, identity: 0.733

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
taaaaaaagaaaaagcatcgtcaattagac	Protospacer
 .* **************.*******

122. spacer 2.4|1052556|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to NC_021559 (Prochlorococcus phage P-SSM3 genomic sequence) position: , mismatch: 8, identity: 0.733

aataatcagtttaaaaatccatctggagca	CRISPR spacer
tataagaagtttaaaaatccatctcaaatg	Protospacer
 ****  ***************** .*...

123. spacer 2.3|1052490|30|CP031638|CRISPRCasFinder,CRT,PILER-CR matches to MN694808 (Marine virus AFVG_250M14, complete genome) position: , mismatch: 9, identity: 0.7

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
caggaaaagaaaaaggattgtcaataccct	Protospacer
 .. *********** ********* .*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36552 : 48853

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB25081.1\|36552_40278_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.1e-38	26.3
QBB25082.1\|40438_41893_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	32.7
QBB25083.1\|41920_42931_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	8.3e-61	41.5
QBB25084.1\|43098_43653_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.8e-25	35.6
QBB25085.1\|43836_45384_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.4e-45	52.4
QBB25086.1\|45441_46566_-	CHAP domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
QBB25087.1\|46818_48084_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
QBB25088.1\|48361_48853_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.1e-17	41.6

DBSCAN-SWA_2

409027 : 464137

Streptococcus_phage(79.17%)

capsid,terminase,portal,tail,head,integrase,tRNA

attL 421668:421684|attR 452385:452401

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB25404.1\|409027_410305_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.6e-93	52.2
QBB25405.1\|410696_411056_-	DUF956 family protein	NA	NA	NA	NA
QBB25406.1\|411169_412081_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
QBB25407.1\|412097_412907_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
QBB25408.1\|412995_413988_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
QBB25409.1\|414339_415152_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
QBB25410.1\|415415_416876_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	9.2e-37	28.6
QBB25411.1\|417029_417491_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
QBB25412.1\|417465_417990_+	N-acetyltransferase	NA	NA	NA	NA
QBB25413.1\|417998_419282_+	LytR family transcriptional regulator	NA	NA	NA	NA
QBB25414.1\|419392_419749_-	chemotaxis protein	NA	NA	NA	NA
QBB25415.1\|419745_420165_-	HIT family protein	NA	NA	NA	NA
QBB25416.1\|420236_420962_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.9e-20	28.0
QBB25417.1\|420964_421999_+	multidrug ABC transporter permease	NA	NA	NA	NA
421668:421684	attL	NA	NA	NA	NA
QBB25418.1\|422062_422854_+	aminoglycoside phosphotransferase	NA	NA	NA	NA
QBB25419.1\|422853_423489_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
QBB25420.1\|423686_424766_-\|integrase	site-specific integrase	A7J266	Streptococcus_phage	1.3e-176	86.9
QBB25421.1\|424882_425434_-	hypothetical protein	A7J267	Streptococcus_phage	3.4e-85	92.3
QBB25422.1\|425444_425828_-	ImmA/IrrE family metallo-endopeptidase	A7J268	Streptococcus_phage	5.3e-69	99.2
QBB25423.1\|425841_426243_-	XRE family transcriptional regulator	A7J269	Streptococcus_phage	1.1e-40	72.9
QBB25424.1\|426653_427067_-	hypothetical protein	NA	NA	NA	NA
QBB25425.1\|427114_427330_+	transcriptional regulator	M1Q1B4	Streptococcus_phage	4.2e-23	76.8
QBB25426.1\|427391_427667_+	DNA-binding protein	A7J272	Streptococcus_phage	5.9e-46	95.6
QBB25427.1\|427663_427834_+	hypothetical protein	A7J273	Streptococcus_phage	6.9e-21	89.3
QBB25428.1\|427826_428030_+	hypothetical protein	NA	NA	NA	NA
QBB25429.1\|428026_428413_+	hypothetical protein	A7J274	Streptococcus_phage	3.1e-56	88.2
QBB25430.1\|428559_428763_+	hypothetical protein	A7J276	Streptococcus_phage	2.3e-31	95.5
QBB25431.1\|428850_429150_+	hypothetical protein	A7J277	Streptococcus_phage	1.8e-43	100.0
QBB25432.1\|429149_430304_+	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	4.5e-204	91.9
QBB25433.1\|430307_430706_+	hypothetical protein	NA	NA	NA	NA
QBB25434.1\|430716_431274_+	DUF2815 family protein	D2J040	Enterococcus_phage	2.5e-51	57.9
QBB25435.1\|431316_433239_+	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	96.7
QBB25436.1\|433243_435628_+	DNA primase	A7J282	Streptococcus_phage	4.1e-276	94.4
QBB25437.1\|436014_436290_+	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	5.9e-46	98.9
QBB25438.1\|436286_437609_+	DEAD/DEAH box helicase	A7J284	Streptococcus_phage	1.9e-254	98.4
QBB25439.1\|437773_438040_+	hypothetical protein	A7J287	Streptococcus_phage	5.4e-20	65.2
QBB25440.1\|438048_438900_+	site-specific DNA-methyltransferase	A0A1W6JMZ7	Lactococcus_phage	1.5e-100	71.9
QBB25441.1\|438889_439081_+	hypothetical protein	NA	NA	NA	NA
QBB25442.1\|439077_439494_+	DUF722 domain-containing protein	A7J289	Streptococcus_phage	6.6e-73	100.0
QBB26706.1\|439583_440036_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	6.9e-76	100.0
QBB25443.1\|440025_441303_+\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	1.3e-241	97.6
QBB25444.1\|441318_442851_+\|portal	phage portal protein	A7J292	Streptococcus_phage	1.3e-286	98.2
QBB25445.1\|442810_444256_+\|head	phage head morphogenesis protein	A7J293	Streptococcus_phage	3.4e-257	92.9
QBB25446.1\|444286_444475_+	hypothetical protein	A7J294	Streptococcus_phage	1.4e-22	98.4
QBB25447.1\|444477_444744_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.7e-34	88.6
QBB25448.1\|444899_445469_+	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	2.6e-80	97.9
QBB25449.1\|445481_446369_+\|capsid	phage capsid protein	A7J297	Streptococcus_phage	3.6e-161	99.7
QBB25450.1\|446380_446737_+	hypothetical protein	A7J298	Streptococcus_phage	2.8e-56	97.5
QBB25451.1\|446747_447026_+	hypothetical protein	A7J299	Streptococcus_phage	4.2e-47	98.9
QBB25452.1\|447022_447367_+	HK97 gp10 family phage protein	A7J2A0	Streptococcus_phage	6.1e-56	99.1
QBB25453.1\|447370_447730_+	hypothetical protein	A7J2A1	Streptococcus_phage	6.8e-58	97.5
QBB25454.1\|447741_448341_+\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	4.1e-92	98.9
QBB25455.1\|448394_448850_+	hypothetical protein	A7J2A3	Streptococcus_phage	8.3e-77	100.0
QBB25456.1\|448924_449158_+	hypothetical protein	A7J2A4	Streptococcus_phage	4.4e-34	100.0
QBB25457.1\|449172_453555_+\|tail	phage tail protein	A7J2A5	Streptococcus_phage	3.2e-226	76.4
452385:452401	attR	NA	NA	NA	NA
QBB25458.1\|453566_454409_+\|tail	phage tail protein	A7J2A6	Streptococcus_phage	8.5e-160	99.6
QBB25459.1\|454418_456401_+	peptidase	A7J2A7	Streptococcus_phage	0.0e+00	92.5
QBB25460.1\|456397_457612_+	hypothetical protein	A3F657	Streptococcus_phage	2.3e-49	40.6
QBB25461.1\|457598_457928_+	hypothetical protein	NA	NA	NA	NA
QBB25462.1\|457938_459834_+	hyaluronidase	Q938J9	Temperate_phage	2.2e-75	52.3
QBB25463.1\|459847_460009_+	hypothetical protein	NA	NA	NA	NA
QBB25464.1\|460011_460632_+	hypothetical protein	A3F662	Streptococcus_phage	8.3e-80	88.8
QBB25465.1\|460642_460942_+	hypothetical protein	Q938J6	Temperate_phage	3.5e-36	82.3
QBB25466.1\|460938_461124_+	hypothetical protein	Q938J5	Temperate_phage	9.5e-24	93.4
QBB25467.1\|461234_462431_+	CHAP domain-containing protein	Q938J4	Temperate_phage	6.1e-196	82.2
QBB25468.1\|462546_463719_-	streptodornase	A7J2B8	Streptococcus_phage	4.7e-76	49.8
QBB25469.1\|463957_464137_+	Paratox	A3F673	Streptococcus_phage	5.6e-21	83.1

DBSCAN-SWA_3

1197115 : 1207719

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB26117.1\|1197115_1198258_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3
QBB26118.1\|1198492_1198933_+	hypothetical protein	NA	NA	NA	NA
QBB26119.1\|1198962_1200231_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
QBB26120.1\|1200318_1201671_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.7
QBB26121.1\|1201892_1202234_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
QBB26122.1\|1202294_1203461_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
QBB26123.1\|1203554_1204241_-	3-dehydroquinase	W6LP76	Streptococcus_phage	7.0e-88	68.9
QBB26124.1\|1204237_1205401_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.5e-143	64.9
QBB26125.1\|1205508_1207719_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.5e-267	68.8

DBSCAN-SWA_4

1485899 : 1491773

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB26371.1\|1485899_1486727_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
QBB26372.1\|1486800_1487157_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
QBB26373.1\|1487455_1488085_+	copper homeostasis protein CutC	NA	NA	NA	NA
QBB26374.1\|1488131_1488524_-	hypothetical protein	NA	NA	NA	NA
QBB26375.1\|1488550_1489414_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
QBB26376.1\|1489418_1489742_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
QBB26377.1\|1490244_1491120_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
QBB26378.1\|1491137_1491773_-	thymidylate kinase	M1PSC7	Streptococcus_phage	2.7e-65	63.4

DBSCAN-SWA_5

1786892 : 1796880

Streptococcus_phage(75.0%)

integrase

attL 1786466:1786480|attR 1794028:1794042

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1786466:1786480	attL	NA	NA	NA	NA
QBB26643.1\|1786892_1787066_-	DUF2758 domain-containing protein	A0A1X9I5U0	Streptococcus_phage	1.9e-10	59.6
QBB26644.1\|1787352_1788966_-	phage resistance protein	A0A1P8BMF9	Lactococcus_phage	2.4e-147	53.1
QBB26645.1\|1788955_1789477_-	hypothetical protein	NA	NA	NA	NA
QBB26646.1\|1789486_1789855_-	hypothetical protein	A0A1X9I6M4	Streptococcus_phage	2.6e-12	47.1
QBB26751.1\|1789763_1789955_-	hypothetical protein	NA	NA	NA	NA
QBB26647.1\|1789954_1790287_-	hypothetical protein	NA	NA	NA	NA
QBB26648.1\|1790298_1790481_-	hypothetical protein	NA	NA	NA	NA
QBB26649.1\|1790701_1790971_-	phage antirepressor protein	NA	NA	NA	NA
QBB26650.1\|1791000_1791567_-	phage repressor protein	A0A0A7S0G2	Clostridium_phage	5.0e-23	42.9
QBB26651.1\|1791582_1791771_-	XRE family transcriptional regulator	A0A1X9I5U7	Streptococcus_phage	1.7e-12	59.7
QBB26652.1\|1791939_1792383_+	XRE family transcriptional regulator	A0A1X9I723	Streptococcus_phage	1.8e-07	48.6
QBB26653.1\|1792562_1793726_+\|integrase	site-specific integrase	A0A1X9I6A9	Streptococcus_phage	2.8e-161	70.5
QBB26654.1\|1793882_1794494_-	30S ribosomal protein S4	NA	NA	NA	NA
1794028:1794042	attR	NA	NA	NA	NA
QBB26655.1\|1795223_1795496_-	hypothetical protein	NA	NA	NA	NA
QBB26656.1\|1795512_1796880_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.0e-154	63.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP031638

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection