CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP031618	Streptococcus pyogenes strain MGAS29326 chromosome, complete genome	3 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csn2,cas9,csm6,DinG,csa3	0	7	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP031618_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031618_1

605065-605227

TypeI

I-C

Consensus_repeat	Method
TAGTCTCACCCTTCATGGGTGAGTGGATTGAAA	PILER-CR

2 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of CP031618_1

>merge|CP031618|1|605065-605227|PILER-CR
AGTCTCACCCTTCATGGGTGAGTGGATTGAAATAAATAATTACATGACTAGCCAATACACCCACATAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTTCATGAGCTTCTTTACTCTCAAAGTAAGAGTGGTCTCACCCTTCATGGGTGAGTGGATTGAAA

>CP031618|1|1|605065-605227|PILER-CR
AGTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACAT
AGTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGT
GGTCTCACCCTTCATGGGTGAGTGGATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP031618.1\|QBB60802.1\|602916_603591_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
CP031618.1\|QBB60814.1\|614057_615293_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
CP031618.1\|QBB60796.1\|593530_594094_+\|shikimate-kinase	unknown	unknown	unknown
CP031618.1\|QBB60797.1\|594095_596744_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP031618.1\|QBB60799.1\|599438_600167_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
CP031618.1\|QBB60803.1\|603587_604613_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
CP031618.1\|QBB60807.1\|606776_607883_+\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|184456
CP031618.1\|QBB60812.1\|612488_612962_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
CP031618.1\|QBB60801.1\|602066_602915_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
CP031618.1\|QBB60811.1\|611606_612323_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225917
CP031618.1\|QBB60800.1\|600166_602062_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|273839
CP031618.1\|QBB60808.1\|607970_608711_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|227095
CP031618.1\|QBB60795.1\|593354_593534_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
CP031618.1\|QBB60805.1\|605387_606098_+\|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl\|CDD\|223856
CP031618.1\|QBB60804.1\|604623_604917_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
CP031618.1\|QBB60798.1\|596897_599306_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP031618.1\|QBB60810.1\|610513_611593_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
CP031618.1\|QBB60806.1\|606110_606734_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
CP031618.1\|QBB60813.1\|613103_613784_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
CP031618.1\|QBB60809.1\|608707_610441_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519

Protein	Function_ID	Function_description	E-value
CP031618.1\|QBB60802.1\|602916_603591_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	3.0744e-43
CP031618.1\|QBB60814.1\|614057_615293_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
CP031618.1\|QBB60797.1\|594095_596744_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
CP031618.1\|QBB60799.1\|599438_600167_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.32713e-117
CP031618.1\|QBB60803.1\|603587_604613_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
CP031618.1\|QBB60807.1\|606776_607883_+\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	3.04644e-163
CP031618.1\|QBB60812.1\|612488_612962_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.23847e-66
CP031618.1\|QBB60801.1\|602066_602915_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	2.68212e-160
CP031618.1\|QBB60811.1\|611606_612323_+\|hypothetical-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	8.83652e-106
CP031618.1\|QBB60800.1\|600166_602062_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
CP031618.1\|QBB60808.1\|607970_608711_+\|DNA-binding-response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	6.22184e-83
CP031618.1\|QBB60795.1\|593354_593534_+\|N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	3.61304e-12
CP031618.1\|QBB60805.1\|605387_606098_+\|cytochrome-c-biogenesis-protein-CcdA	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	2.85986e-42
CP031618.1\|QBB60804.1\|604623_604917_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
CP031618.1\|QBB60798.1\|596897_599306_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.76387e-159
CP031618.1\|QBB60810.1\|610513_611593_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.18444e-35
CP031618.1\|QBB60806.1\|606110_606734_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.08316e-34
CP031618.1\|QBB60813.1\|613103_613784_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
CP031618.1\|QBB60809.1\|608707_610441_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.03945e-65

>CP031618.1|QBB60804.1|604623_604917_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>CP031618.1|QBB60803.1|603587_604613_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>CP031618.1|QBB60802.1|602916_603591_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>CP031618.1|QBB60801.1|602066_602915_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>CP031618.1|QBB60800.1|600166_602062_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMLKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>CP031618.1|QBB60799.1|599438_600167_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>CP031618.1|QBB60798.1|596897_599306_+|CRISPR-associated-helicase/endonuclease-Cas3
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>CP031618.1|QBB60797.1|594095_596744_+|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIVRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQAKYDATQERIAEMKKIKS
>CP031618.1|QBB60796.1|593530_594094_+|shikimate-kinase
MNLIIIGAQASGKMTIEQEVARQTGMNLFHNHDSIDFVLRFMPWSQESTALIERMRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>CP031618.1|QBB60795.1|593354_593534_+|N-acetyltransferase
MHKIELGCYDYNKQSQAVARKLGFTLEANVRERKDVQGRRCGGMRFGLLRSEWEEQKQK
>CP031618.1|QBB60805.1|605387_606098_+|cytochrome-c-biogenesis-protein-CcdA
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHIFLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>CP031618.1|QBB60806.1|606110_606734_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMVKKEITQDKMSMAVKKKDKMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>CP031618.1|QBB60807.1|606776_607883_+|peptide-methionine-(R)-S-oxide-reductase
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>CP031618.1|QBB60808.1|607970_608711_+|DNA-binding-response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>CP031618.1|QBB60809.1|608707_610441_+|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTNLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMHELMADDTQENE
>CP031618.1|QBB60810.1|610513_611593_+|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVEGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETNIPNEGYRKNPNIDKLMRLRKRQQYKDGLLSFDLMKKHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>CP031618.1|QBB60811.1|611606_612323_+|hypothetical-protein
MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHAITSVHVLDKDNPHVPLFTEN
>CP031618.1|QBB60812.1|612488_612962_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>CP031618.1|QBB60813.1|613103_613784_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>CP031618.1|QBB60814.1|614057_615293_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Crispr_ID: CP031618_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031618_2

1111313-1111612

TypeII

II-A

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	PILER-CR

4 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP031618_2

>merge|CP031618|2|1111313-1111612|CRISPRCasFinder,CRT,PILER-CR
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAACGGAAAGCAGGAGAAAGGACGTTAATATGTCGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACGTCAAACTCAATTTTTTGTCTAGCTCTATTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAGACAAAAGAAAAAGCATTGTCAATTTCTAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAATAATCAGTTTAAAAATCCATCTGGAGCAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031618|2|1|1111313-1111612|CRISPRCasFinder
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAAC	GGAAAGCAGGAGAAAGGACGTTAATATGTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031618|2|1|1111313-1111612|CRT
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAAC	GGAAAGCAGGAGAAAGGACGTTAATATGTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031618|2|2|1111379-1111612|PILER-CR
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP031618.1\|QBB61276.1\|1104229_1104655_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
CP031618.1\|QBB61288.1\|1119520_1120273_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
CP031618.1\|QBB61274.1\|1102893_1103703_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
CP031618.1\|QBB61286.1\|1118124_1118757_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
CP031618.1\|QBB61289.1\|1120282_1121413_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP031618.1\|QBB62095.1\|1106633_1107608_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
CP031618.1\|QBB61281.1\|1110030_1111164_-\|ISAs1-like-element-IS1548-family-transposase	unknown	unknown	gnl\|CDD\|227720
CP031618.1\|QBB61273.1\|1102069_1102897_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
CP031618.1\|QBB61280.1\|1109921_1110026_-\|exfoliative-toxin	unknown	unknown	unknown
CP031618.1\|QBB61284.1\|1112704_1113574_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP031618.1\|QBB61290.1\|1121475_1122117_-\|hypothetical-protein	unknown	unknown	unknown
CP031618.1\|QBB61275.1\|1103719_1104211_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
CP031618.1\|QBB61287.1\|1118756_1119521_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
CP031618.1\|QBB61278.1\|1106010_1106448_-\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692
CP031618.1\|QBB61291.1\|1122240_1123596_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
CP031618.1\|QBB61279.1\|1108029_1109862_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP031618.1\|QBB61283.1\|1112366_1112708_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP031618.1\|QBB61282.1\|1111714_1112377_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP031618.1\|QBB61277.1\|1104861_1105881_-\|putative-sulfate-exporter-family-transporter	unknown	unknown	gnl\|CDD\|225411
CP031618.1\|QBB61285.1\|1113573_1117680_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044

Protein	Function_ID	Function_description	E-value
CP031618.1\|QBB61276.1\|1104229_1104655_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	1.16501e-30
CP031618.1\|QBB61288.1\|1119520_1120273_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.21279e-109
CP031618.1\|QBB61274.1\|1102893_1103703_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
CP031618.1\|QBB61286.1\|1118124_1118757_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.04206e-87
CP031618.1\|QBB61289.1\|1120282_1121413_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP031618.1\|QBB62095.1\|1106633_1107608_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	9.99312e-10
CP031618.1\|QBB61281.1\|1110030_1111164_-\|ISAs1-like-element-IS1548-family-transposase	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	1.42629e-30
CP031618.1\|QBB61273.1\|1102069_1102897_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
CP031618.1\|QBB61284.1\|1112704_1113574_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.48912e-131
CP031618.1\|QBB61275.1\|1103719_1104211_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
CP031618.1\|QBB61287.1\|1118756_1119521_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.84127e-128
CP031618.1\|QBB61278.1\|1106010_1106448_-\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	5.00558e-84
CP031618.1\|QBB61291.1\|1122240_1123596_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP031618.1\|QBB61279.1\|1108029_1109862_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP031618.1\|QBB61283.1\|1112366_1112708_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.79e-58
CP031618.1\|QBB61282.1\|1111714_1112377_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.6851e-120
CP031618.1\|QBB61277.1\|1104861_1105881_-\|putative-sulfate-exporter-family-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	3.12379e-103
CP031618.1\|QBB61285.1\|1113573_1117680_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0

>CP031618.1|QBB61281.1|1110030_1111164_-|ISAs1-like-element-IS1548-family-transposase
MIDFIISIDDCAVELDSRQSWKIGYPLSTILFLVFVCQLAGIETWKEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQSLTSLDAVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNFIRKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG
>CP031618.1|QBB61280.1|1109921_1110026_-|exfoliative-toxin
MIDLKRNLFKIDVRAQKDEEKVFMRTAWIIRKKR
>CP031618.1|QBB61279.1|1108029_1109862_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
>CP031618.1|QBB62095.1|1106633_1107608_-|LPXTG-cell-wall-anchor-domain-containing-protein
MTKLLTYLQEREQAENSWRKRLLKGIQDHALDGQDGRNGERGEQGPTGLAGKAGEAGAKGETGPAGPQGPRGEQGPQGLPGKDGEAGAQGPAGPMGPAGERGEKGEPGTQGAKGDRGETGPVGPRGERGEAGPAGKDGERGPVGPAGKDGQNGQDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>CP031618.1|QBB61278.1|1106010_1106448_-|peptide-methionine-(R)-S-oxide-reductase
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET
>CP031618.1|QBB61277.1|1104861_1105881_-|putative-sulfate-exporter-family-transporter
MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNDGFATFAGTAVNDTSSVTATATAWDALHHSNTLDDATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVSADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>CP031618.1|QBB61276.1|1104229_1104655_-|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDNFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD
>CP031618.1|QBB61275.1|1103719_1104211_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>CP031618.1|QBB61274.1|1102893_1103703_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>CP031618.1|QBB61273.1|1102069_1102897_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>CP031618.1|QBB61282.1|1111714_1112377_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSELKFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>CP031618.1|QBB61283.1|1112366_1112708_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>CP031618.1|QBB61284.1|1112704_1113574_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVKSQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTLFGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKALNNEGKGVPEFRI
>CP031618.1|QBB61285.1|1113573_1117680_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRLNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKVLTRSDKNRGKSNNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIVKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATFIHQSITGLYETRIDLSQLGGD
>CP031618.1|QBB61286.1|1118124_1118757_-|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>CP031618.1|QBB61287.1|1118756_1119521_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>CP031618.1|QBB61288.1|1119520_1120273_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGGLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKPHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>CP031618.1|QBB61289.1|1120282_1121413_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>CP031618.1|QBB61290.1|1121475_1122117_-|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQENLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSRP
>CP031618.1|QBB61291.1|1122240_1123596_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

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Crispr_ID: CP031618_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031618_3

1898646-1898742

Orphan

Consensus_repeat	Method
AAAAACCCAATTTTTTTTCGTCTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP031618_3

>merge|CP031618|3|1898646-1898742|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTATTTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGTCAAGATAAAAATCCAATTTTTTTTCGTCTTAT

>CP031618|3|2|1898646-1898742|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTAT	TTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGTCAAGAT
AAAAATCCAATTTTTTTTCGTCTTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP031618.1\|QBB62005.1\|1893751_1893925_-\|DUF2758-domain-containing-protein	unknown	unknown	unknown
CP031618.1\|QBB62016.1\|1900741_1901353_-\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
CP031618.1\|QBB62022.1\|1908305_1908623_-\|phosphohydrolase	unknown	unknown	gnl\|CDD\|240044
CP031618.1\|QBB62012.1\|1897859_1898426_-\|phage-repressor-protein	unknown	unknown	gnl\|CDD\|226144
CP031618.1\|QBB62123.1\|1896622_1896814_-\|hypothetical-protein	unknown	unknown	unknown
CP031618.1\|QBB62020.1\|1904217_1906194_-\|DHH-family-phosphoesterase	unknown	unknown	gnl\|CDD\|226404
CP031618.1\|QBB62006.1\|1894211_1895825_-\|phage-resistance-protein	unknown	unknown	unknown
CP031618.1\|QBB62008.1\|1896345_1896714_-\|hypothetical-protein	unknown	unknown	unknown
CP031618.1\|QBB62017.1\|1902082_1902355_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226872
CP031618.1\|QBB62018.1\|1902371_1903739_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|180232
CP031618.1\|QBB62009.1\|1896813_1897146_-\|hypothetical-protein	unknown	unknown	unknown
CP031618.1\|QBB62007.1\|1895814_1896336_-\|hypothetical-protein	unknown	unknown	unknown
CP031618.1\|QBB62011.1\|1897560_1897830_-\|phage-antirepressor-protein	unknown	unknown	unknown
CP031618.1\|QBB62015.1\|1899421_1900585_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP031618.1\|QBB62021.1\|1906283_1908182_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
CP031618.1\|QBB62014.1\|1898798_1899242_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031618.1\|QBB62010.1\|1897157_1897340_-\|hypothetical-protein	unknown	unknown	unknown
CP031618.1\|QBB62013.1\|1898441_1898630_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031618.1\|QBB62019.1\|1903768_1904221_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
CP031618.1\|QBB62023.1\|1909398_1910520_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664

Protein	Function_ID	Function_description	E-value
CP031618.1\|QBB62022.1\|1908305_1908623_-\|phosphohydrolase	gnl\|CDD\|240044	cd04688, Nudix_Hydrolase_29, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	7.82374e-17
CP031618.1\|QBB62012.1\|1897859_1898426_-\|phage-repressor-protein	gnl\|CDD\|226144	COG3617, COG3617, Prophage antirepressor [Transcription].	1.58213e-27
CP031618.1\|QBB62020.1\|1904217_1906194_-\|DHH-family-phosphoesterase	gnl\|CDD\|226404	COG3887, COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms].	0
CP031618.1\|QBB62013.1\|1898441_1898630_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00222954
CP031618.1\|QBB62023.1\|1909398_1910520_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
CP031618.1\|QBB62017.1\|1902082_1902355_-\|hypothetical-protein	gnl\|CDD\|226872	COG4466, Veg, Uncharacterized protein conserved in bacteria [Function unknown].	7.52485e-33
CP031618.1\|QBB62018.1\|1902371_1903739_-\|replicative-DNA-helicase	gnl\|CDD\|180232	PRK05748, PRK05748, replicative DNA helicase; Provisional.	0
CP031618.1\|QBB62015.1\|1899421_1900585_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.50808e-45
CP031618.1\|QBB62021.1\|1906283_1908182_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
CP031618.1\|QBB62014.1\|1898798_1899242_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.81587e-06
CP031618.1\|QBB62016.1\|1900741_1901353_-\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	8.00838e-118
CP031618.1\|QBB62019.1\|1903768_1904221_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	1.02239e-55

>CP031618.1|QBB62013.1|1898441_1898630_-|XRE-family-transcriptional-regulator
MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNYKAPKRIYASVMEWLAEDY
>CP031618.1|QBB62012.1|1897859_1898426_-|phage-repressor-protein
MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRARDVAEMIDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEHGLYEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDIDDLSYIKQKLTDLQDVDSLQDLRWKMAKLYHVIETLDEY
>CP031618.1|QBB62011.1|1897560_1897830_-|phage-antirepressor-protein
MRTDKGEMIMKATTYKELKKWIDEGVDLAELAQGYADKVPSVDREQFEAVTQGIFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY
>CP031618.1|QBB62010.1|1897157_1897340_-|hypothetical-protein
MTSVRTAQLLNNGLGLVGQDLKDVLSALANSVNPSIEKQISHIMIDRANTGEWLANVGKK
>CP031618.1|QBB62009.1|1896813_1897146_-|hypothetical-protein
MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQHIAWVIIANVMTEYVNKFRKSATSFEKAWDALGYQQTTEIVFRAVNGLPCSEKDTGELETYLSEVSA
>CP031618.1|QBB62123.1|1896622_1896814_-|hypothetical-protein
MQELNLTPTQTLILFIVLGLVGLLLSLSKPLIEIDLPEDTQVPKPPQNANYGAYIQSQNHYYN
>CP031618.1|QBB62008.1|1896345_1896714_-|hypothetical-protein
MTYQKIPKYLNHLRTQTMGLIFNHRTIITIRREQMQLLSREAELELLEKVGCYLEKRWQLELENKDDWDLIPRQDLLEKLDITGTTLKNWEKEGLKSYQSPFENSKKVYYRKSDIYNFLSVD
>CP031618.1|QBB62007.1|1895814_1896336_-|hypothetical-protein
MDYLEVTMTKDCVKIFNFLYKYPTKAYQKDEYFKLLYMHPLDSFLTSFSLSGIRVKVTDKPVLAGWKLVRDIEVRIATGELLEMIEELEICYLRKHQTVSYVEIKFYVVHLLTYGIRSRYDMQFFTKLLFCCGYDQETVIGIYSNITKNTRLSRDFITLQAKLYQTKKGTHEH
>CP031618.1|QBB62006.1|1894211_1895825_-|phage-resistance-protein
MSIKENIDKLVSMEWTESIFGQSKMKADYKRQLSKVIELDTLSNIHHNGETYAVSNQEVMYLSESKGRTHKFISGNVKTKSKGKGRDSQKYLVVSFDHQFPPFAKLVVDYLLGRFTFFNNKLYDVNNRQAQVLDDFTIQSLYGFKKDNPFILEILEGIHQTLNIRPAKQLEAYKISGRDFIIDLKEHRLYRTNPSSDSSFFKFYDVDYHTAIGSKKKVGKFLDYVIADHDSLHNATLQAYYIAQVACGLKSKQNFFISKSGVRTGKGLRHIGLSGIFNKIDVELDLLIKGGFEASNAWGAFAGGEMALATEQGDIVGDKMERVLKIIATEKTHMARSIGGNLGTVNLTSVLCIDTNRTVALSDEMNGRAVLIQYQNRPEGETDLEREKAFEEYWQTFTEMDKSPKIEGVIGFLLVSLDYFRKNDMKFDWRAVEVVNDDDLDDFQVYLINHLSEKDFVERDSYVRELYNSTYGKNNNQAGQRMRTIGVKSYRKQTTGGRKIPGYKVDNIKRFNKFSGGEKENTNIFDMFEKLNQPLPP
>CP031618.1|QBB62005.1|1893751_1893925_-|DUF2758-domain-containing-protein
MKIKLFYQKHNESLDDFEYRVNQFTLSVSVIDIKLSEATYGNYEDMSTTTSLLVLYR
>CP031618.1|QBB62014.1|1898798_1899242_+|XRE-family-transcriptional-regulator
MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENPKNTIKPDKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFSFDMTATESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP
>CP031618.1|QBB62015.1|1899421_1900585_+|site-specific-integrase
MNIKEYKKKNGTIIYRTSVYLGVDQVTGKKARTTITASTKKGVKIKARDALNNFAMNGYTVKEKPTVTTYKELTALWWESYKNTIKPNSRQSMEGIVRLHILPAFGDCKLSKLTTPVIQQQVNKWANNANKGIKGAYANYSFLNNINRRILQYGVTMQVIEHNPARDVIIPRKQNNKEHKVKFFSNQELKQFLNYLDDLDLSSYENFFDYVLYKTLLATGCRIGEVLALEWSDIDLKKGTIKVSKTLNRYQETNTPKSKAGLRDIEIDRATVLLLKQYKNRQQVLSWDLGRSETIVFTPFTTKYAYACLLRKRLQKHFKAAGVPDISFHGFRHTHATIMLYAGIEAKDLQYRLGHSNISMTLNTYVHATKEGAKKAVSIFETAISNL
>CP031618.1|QBB62016.1|1900741_1901353_-|30S-ribosomal-protein-S4
MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
>CP031618.1|QBB62017.1|1902082_1902355_-|hypothetical-protein
MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRLIEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD
>CP031618.1|QBB62018.1|1902371_1903739_-|replicative-DNA-helicase
MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER
>CP031618.1|QBB62019.1|1903768_1904221_-|50S-ribosomal-protein-L9
MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLTITEA
>CP031618.1|QBB62020.1|1904217_1906194_-|DHH-family-phosphoesterase
MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLLFVVALLWYQKEAYHLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNPYAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSFVGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFYRRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQIGQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDRIKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDFPDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTSRTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLYSNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFNLAACQLTDISLPQAKHLLLKTINMTMKETGEVES
>CP031618.1|QBB62021.1|1906283_1908182_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
>CP031618.1|QBB62022.1|1908305_1908623_-|phosphohydrolase
MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVGIRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSINWIK
>CP031618.1|QBB62023.1|1909398_1910520_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448767	Streptococcus phage Javan467, complete genome	17890-17919	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448685	Streptococcus phage Javan155, complete genome	18198-18227	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448771	Streptococcus phage Javan481, complete genome	17415-17444	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448829	Streptococcus phage Javan7, complete genome	19776-19805	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448736	Streptococcus phage Javan35, complete genome	20259-20288	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448781	Streptococcus phage Javan5, complete genome	22281-22310	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK449012	Streptococcus phage Javan94, complete genome	19127-19156	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	17995-18024	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448969	Streptococcus phage Javan514, complete genome	19138-19167	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MH853355	Streptococcus phage LF1, complete genome	10633-10662	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448964	Streptococcus phage Javan502, complete genome	17719-17748	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448943	Streptococcus phage Javan450, complete genome	17890-17919	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448972	Streptococcus phage Javan520, complete genome	17264-17293	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448938	Streptococcus phage Javan44, complete genome	20260-20289	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448855	Streptococcus phage Javan150, complete genome	18394-18423	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448786	Streptococcus phage Javan509, complete genome	17890-17919	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448774	Streptococcus phage Javan487, complete genome	16251-16280	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448963	Streptococcus phage Javan498, complete genome	13512-13541	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448773	Streptococcus phage Javan485, complete genome	19137-19166	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448911	Streptococcus phage Javan34, complete genome	20259-20288	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448837	Streptococcus phage Javan10, complete genome	18305-18334	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448742	Streptococcus phage Javan37, complete genome	20096-20125	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MH853358	Streptococcus phage LF4, complete genome	10633-10662	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448845	Streptococcus phage Javan118, complete genome	18668-18697	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448916	Streptococcus phage Javan36, complete genome	20259-20288	0	1.0
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448853	Streptococcus phage Javan144, complete genome	18198-18227	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448871	Streptococcus phage Javan196, complete genome	33084-33113	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448697	Streptococcus phage Javan185, complete genome	33084-33113	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448693	Streptococcus phage Javan177, complete genome	33084-33113	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448772	Streptococcus phage Javan483, complete genome	32792-32821	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448696	Streptococcus phage Javan183, complete genome	33084-33113	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	NC_009819	Streptococcus phage P9, complete genome	32033-32062	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448793	Streptococcus phage Javan523, complete genome	33428-33457	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448868	Streptococcus phage Javan188, complete genome	33085-33114	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448866	Streptococcus phage Javan184, complete genome	33084-33113	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448954	Streptococcus phage Javan476, complete genome	31815-31844	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448699	Streptococcus phage Javan189, complete genome	33084-33113	0	1.0
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448867	Streptococcus phage Javan186, complete genome	33084-33113	0	1.0
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448775	Streptococcus phage Javan489, complete genome	25298-25327	0	1.0
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448794	Streptococcus phage Javan525, complete genome	22421-22450	0	1.0
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448953	Streptococcus phage Javan474, complete genome	27019-27048	0	1.0
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448765	Streptococcus phage Javan459, complete genome	22420-22449	0	1.0
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448957	Streptococcus phage Javan484, complete genome	27899-27928	0	1.0
CP031618_2	2.4\|1111547\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111547-1111576	30	MK448662	Streptococcus satellite phage Javan97, complete genome	6081-6110	0	1.0
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448522	Streptococcus satellite phage Javan519, complete genome	1870-1914	0	1.0
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448330	Streptococcus satellite phage Javan136, complete genome	2770-2814	0	1.0
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448328	Streptococcus satellite phage Javan130, complete genome	2770-2814	0	1.0
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448513	Streptococcus satellite phage Javan479, complete genome	1870-1914	0	1.0
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448332	Streptococcus satellite phage Javan142, complete genome	2777-2821	0	1.0
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448331	Streptococcus satellite phage Javan138, complete genome	2777-2821	0	1.0
CP031618_1	1.1\|605098\|33\|CP031618\|PILER-CR	605098-605130	33	MK448762	Streptococcus phage Javan447, complete genome	57-89	1	0.97
CP031618_1	1.1\|605098\|33\|CP031618\|PILER-CR	605098-605130	33	MK448798	Streptococcus phage Javan533, complete genome	57-89	1	0.97
CP031618_1	1.1\|605098\|33\|CP031618\|PILER-CR	605098-605130	33	MK448793	Streptococcus phage Javan523, complete genome	57-89	1	0.97
CP031618_1	1.1\|605098\|33\|CP031618\|PILER-CR	605098-605130	33	MK448967	Streptococcus phage Javan510, complete genome	57-89	1	0.97
CP031618_1	1.1\|605098\|33\|CP031618\|PILER-CR	605098-605130	33	MK448954	Streptococcus phage Javan476, complete genome	57-89	1	0.97
CP031618_1	1.1\|605098\|33\|CP031618\|PILER-CR	605098-605130	33	NC_004588	Streptococcus prophage 315.5, complete genome	206-238	1	0.97
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448771	Streptococcus phage Javan481, complete genome	6936-6967	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448681	Streptococcus phage Javan141, complete genome	6534-6565	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448944	Streptococcus phage Javan452, complete genome	11200-11231	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448672	Streptococcus phage Javan117, complete genome	6782-6813	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448849	Streptococcus phage Javan128, complete genome	6685-6716	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448774	Streptococcus phage Javan487, complete genome	6921-6952	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448958	Streptococcus phage Javan486, complete genome	9165-9196	1	0.969
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448742	Streptococcus phage Javan37, complete genome	9157-9188	1	0.969
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448946	Streptococcus phage Javan456, complete genome	36512-36541	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448779	Streptococcus phage Javan497, complete genome	31741-31770	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448795	Streptococcus phage Javan527, complete genome	38519-38548	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448944	Streptococcus phage Javan452, complete genome	35553-35582	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448968	Streptococcus phage Javan512, complete genome	31741-31770	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	NC_004584	Streptococcus prophage 315.1, complete genome	31585-31614	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448797	Streptococcus phage Javan531, complete genome	31741-31770	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448978	Streptococcus phage Javan532, complete genome	31479-31508	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448785	Streptococcus phage Javan507, complete genome	31480-31509	1	0.967
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	NC_004589	Streptococcus prophage 315.6, complete genome	31838-31867	1	0.967
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448946	Streptococcus phage Javan456, complete genome	26948-26977	1	0.967
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448333	Streptococcus satellite phage Javan145, complete genome	2769-2813	1	0.978
CP031618_3	3.1\|1898672\|45\|CP031618\|CRISPRCasFinder	1898672-1898716	45	MK448340	Streptococcus satellite phage Javan156, complete genome	2769-2813	1	0.978
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448767	Streptococcus phage Javan467, complete genome	6874-6905	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448973	Streptococcus phage Javan522, complete genome	8841-8872	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448862	Streptococcus phage Javan178, complete genome	6910-6941	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448942	Streptococcus phage Javan448, complete genome	6873-6904	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK449010	Streptococcus phage Javan90, complete genome	9369-9400	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK449012	Streptococcus phage Javan94, complete genome	8203-8234	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	6979-7010	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448969	Streptococcus phage Javan514, complete genome	9629-9660	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448943	Streptococcus phage Javan450, complete genome	6874-6905	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448972	Streptococcus phage Javan520, complete genome	6683-6714	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448786	Streptococcus phage Javan509, complete genome	6874-6905	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448778	Streptococcus phage Javan493, complete genome	8856-8887	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448963	Streptococcus phage Javan498, complete genome	3463-3494	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448773	Streptococcus phage Javan485, complete genome	9629-9660	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448851	Streptococcus phage Javan14, complete genome	12142-12173	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448833	Streptococcus phage Javan87, complete genome	9369-9400	2	0.938
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448673	Streptococcus phage Javan119, complete genome	9948-9979	2	0.938
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448755	Streptococcus phage Javan423, complete genome	19783-19812	2	0.933
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	MK448756	Streptococcus phage Javan425, complete genome	19783-19812	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448771	Streptococcus phage Javan481, complete genome	26991-27020	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448942	Streptococcus phage Javan448, complete genome	18422-18451	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448794	Streptococcus phage Javan525, complete genome	32018-32047	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448964	Streptococcus phage Javan502, complete genome	27279-27308	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	M19348	Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds	511-540	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448951	Streptococcus phage Javan470, complete genome	32170-32199	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448765	Streptococcus phage Javan459, complete genome	32016-32045	2	0.933
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448764	Streptococcus phage Javan457, complete genome	25122-25151	2	0.933
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MK448933	Streptococcus phage Javan420, complete genome	26823-26852	2	0.933
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448964	Streptococcus phage Javan502, complete genome	6853-6884	3	0.906
CP031618_2	2.1\|1111349\|30\|CP031618\|CRISPRCasFinder,CRT	1111349-1111378	30	NC_028666	Streptococcus phage Str-PAP-1, complete genome	24240-24269	3	0.9
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	NZ_CP020429	Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence	100887-100918	4	0.875
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	NZ_CP020439	Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence	133702-133733	4	0.875
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	NZ_CP018188	Streptococcus salivarius strain ICDC2 plasmid, complete sequence	108973-109004	4	0.875
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	18924-18955	4	0.875
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MN480763	Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence	119912-119943	4	0.875
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448698	Streptococcus phage Javan187, complete genome	27333-27362	4	0.867
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448845	Streptococcus phage Javan118, complete genome	8663-8694	5	0.844
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448767	Streptococcus phage Javan467, complete genome	27472-27501	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	27577-27606	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448976	Streptococcus phage Javan528, complete genome	32036-32065	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448943	Streptococcus phage Javan450, complete genome	27472-27501	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448972	Streptococcus phage Javan520, complete genome	27647-27676	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448786	Streptococcus phage Javan509, complete genome	27472-27501	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448963	Streptococcus phage Javan498, complete genome	23094-23123	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448773	Streptococcus phage Javan485, complete genome	28601-28630	5	0.833
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MK448950	Streptococcus phage Javan464, complete genome	32684-32713	6	0.8
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	MN693570	Marine virus AFVG_25M8, complete genome	48011-48040	6	0.8
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	NZ_CP014852	Bacillus thuringiensis strain HD12 plasmid pHD120161, complete sequence	135700-135729	7	0.767
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	NC_010895	Bacillus thuringiensis serovar tenebrionis plasmid pBMB175, complete sequence	869-898	7	0.767
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	CP020760	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-21, complete sequence	3892-3921	7	0.767
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	NC_005567	Bacillus thuringiensis H1.1 plasmid pGI3, complete sequence	1823-1852	7	0.767
CP031618_1	1.2\|605164\|32\|CP031618\|PILER-CR	605164-605195	32	MK448704	Streptococcus phage Javan213, complete genome	8201-8232	8	0.75
CP031618_2	2.2\|1111415\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111415-1111444	30	NC_013792	Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence	63431-63460	8	0.733
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	NZ_CP031836	Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence	84673-84702	8	0.733
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	NZ_CP020458	Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence	86560-86589	8	0.733
CP031618_2	2.4\|1111547\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111547-1111576	30	NC_021559	Prochlorococcus phage P-SSM3 genomic sequence	77011-77040	8	0.733
CP031618_2	2.3\|1111481\|30\|CP031618\|CRISPRCasFinder,CRT,PILER-CR	1111481-1111510	30	MN694808	Marine virus AFVG_250M14, complete genome	476-505	9	0.7

1. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

2. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

3. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

4. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448829 (Streptococcus phage Javan7, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

5. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

6. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

7. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

8. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

9. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

10. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MH853355 (Streptococcus phage LF1, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

11. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

12. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

13. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

14. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

15. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

16. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

17. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

18. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

19. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

20. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

21. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

22. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

23. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MH853358 (Streptococcus phage LF4, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

24. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

25. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

26. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

27. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

28. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

29. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

30. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

31. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

32. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

33. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

34. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

35. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

36. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

37. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

38. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

39. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

40. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

41. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

42. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

43. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

44. spacer 2.4|1111547|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448662 (Streptococcus satellite phage Javan97, complete genome) position: , mismatch: 0, identity: 1.0

aataatcagtttaaaaatccatctggagca	CRISPR spacer
aataatcagtttaaaaatccatctggagca	Protospacer
******************************

45. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448522 (Streptococcus satellite phage Javan519, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

46. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448330 (Streptococcus satellite phage Javan136, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

47. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448328 (Streptococcus satellite phage Javan130, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

48. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448513 (Streptococcus satellite phage Javan479, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

49. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448332 (Streptococcus satellite phage Javan142, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

50. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448331 (Streptococcus satellite phage Javan138, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

51. spacer 1.1|605098|33|CP031618|PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

52. spacer 1.1|605098|33|CP031618|PILER-CR matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

53. spacer 1.1|605098|33|CP031618|PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

54. spacer 1.1|605098|33|CP031618|PILER-CR matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

55. spacer 1.1|605098|33|CP031618|PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

56. spacer 1.1|605098|33|CP031618|PILER-CR matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

57. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

58. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

59. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

60. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

61. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

62. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

63. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

64. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

65. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtttagctctatt	Protospacer
*******************.**********

66. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

67. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

68. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

69. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

70. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

71. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

72. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

73. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

74. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

75. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.967

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttctg	Protospacer
*****************************.

76. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448333 (Streptococcus satellite phage Javan145, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
**************************************.******

77. spacer 3.1|1898672|45|CP031618|CRISPRCasFinder matches to MK448340 (Streptococcus satellite phage Javan156, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
**************************************.******

78. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

79. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

80. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

81. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

82. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

83. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

84. spacer 1.2|605164|32|CP031618|PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

85. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

86. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

87. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

88. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

89. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

90. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

91. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

92. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

93. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

94. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

95. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448755 (Streptococcus phage Javan423, complete genome) position: , mismatch: 2, identity: 0.933

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttatcatgtc	Protospacer
*********************** .*****

96. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to MK448756 (Streptococcus phage Javan425, complete genome) position: , mismatch: 2, identity: 0.933

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttatcatgtc	Protospacer
*********************** .*****

97. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

98. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

99. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

100. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

101. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to M19348 (Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

102. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaattcaattttttgtttagctctatt	Protospacer
******.************.**********

103. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

104. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

105. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 2, identity: 0.933

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatctctg	Protospacer
*************************.***.

106. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 3, identity: 0.906

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttaccctcaaagtaagag	Protospacer
.***********.*****.*************

107. spacer 2.1|1111349|30|CP031618|CRISPRCasFinder,CRT matches to NC_028666 (Streptococcus phage Str-PAP-1, complete genome) position: , mismatch: 3, identity: 0.9

ggaaagcaggagaaaggacgttaatatgtc-	CRISPR spacer
gcaaagcaggagaaaggacgtt-acatgtca	Protospacer
* ******************** *.*****

108. spacer 1.2|605164|32|CP031618|PILER-CR matches to NZ_CP020429 (Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttagtctcaaaataagaa	Protospacer
.**************** *******.*****.

109. spacer 1.2|605164|32|CP031618|PILER-CR matches to NZ_CP020439 (Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttagtctcaaaataagaa	Protospacer
.**************** *******.*****.

110. spacer 1.2|605164|32|CP031618|PILER-CR matches to NZ_CP018188 (Streptococcus salivarius strain ICDC2 plasmid, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttattctcaaaataagaa	Protospacer
.****************.*******.*****.

111. spacer 1.2|605164|32|CP031618|PILER-CR matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttattctcaaaataagaa	Protospacer
.****************.*******.*****.

112. spacer 1.2|605164|32|CP031618|PILER-CR matches to MN480763 (Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttagtctcaaaataagaa	Protospacer
.**************** *******.*****.

113. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 4, identity: 0.867

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctttgca	Protospacer
*************************.*..

114. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 5, identity: 0.844

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
tggaataagctgctttactctcaaagtaagag	Protospacer
*   **.**** ********************

115. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

116. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

117. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448976 (Streptococcus phage Javan528, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

118. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

119. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

120. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

121. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

122. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

123. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 6, identity: 0.8

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttccgtctagctttgca	Protospacer
***************..********.*..

124. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MN693570 (Marine virus AFVG_25M8, complete genome) position: , mismatch: 6, identity: 0.8

gtcaaactcaattttttgtctagc-tctatt	CRISPR spacer
attaaactcaattttttgactagcatgtaa-	Protospacer
.*.*************** ***** * **

125. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014852 (Bacillus thuringiensis strain HD12 plasmid pHD120161, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
caccagaagcaaaagcattgtcaatttccg	Protospacer
 . **.*** ******************..

126. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_010895 (Bacillus thuringiensis serovar tenebrionis plasmid pBMB175, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttact	Protospacer
*.* *********** ***.******* .

127. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to CP020760 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-21, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttacc	Protospacer
*.* *********** ***.******* .

128. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_005567 (Bacillus thuringiensis H1.1 plasmid pGI3, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttacc	Protospacer
*.* *********** ***.******* .

129. spacer 1.2|605164|32|CP031618|PILER-CR matches to MK448704 (Streptococcus phage Javan213, complete genome) position: , mismatch: 8, identity: 0.75

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
ttgcatgagcttctttgctctcaaatgcgctg	Protospacer
** *************.********   .  *

130. spacer 2.2|1111415|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_013792 (Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence) position: , mismatch: 8, identity: 0.733

---gtcaaactcaattttttgtctagctctatt	CRISPR spacer
ccttttga---taatttcttgtctagctctatt	Protospacer
    *..*   .*****.***************

131. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031836 (Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
taaaaaaagaaaaagcatcgtcaattagac	Protospacer
 .* **************.*******

132. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020458 (Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence) position: , mismatch: 8, identity: 0.733

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
taaaaaaagaaaaagcatcgtcaattagac	Protospacer
 .* **************.*******

133. spacer 2.4|1111547|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to NC_021559 (Prochlorococcus phage P-SSM3 genomic sequence) position: , mismatch: 8, identity: 0.733

aataatcagtttaaaaatccatctggagca	CRISPR spacer
tataagaagtttaaaaatccatctcaaatg	Protospacer
 ****  ***************** .*...

134. spacer 2.3|1111481|30|CP031618|CRISPRCasFinder,CRT,PILER-CR matches to MN694808 (Marine virus AFVG_250M14, complete genome) position: , mismatch: 9, identity: 0.7

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
caggaaaagaaaaaggattgtcaataccct	Protospacer
 .. *********** ********* .*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36552 : 48865

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB60320.1\|36552_40278_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.1e-38	26.3
QBB60321.1\|40438_41893_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	32.7
QBB60322.1\|41920_42943_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	2.4e-63	42.1
QBB60323.1\|43110_43665_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.8e-25	35.6
QBB60324.1\|43848_45396_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.4e-45	52.4
QBB60325.1\|45453_46578_-	CHAP domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
QBB60326.1\|46830_48096_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
QBB60327.1\|48373_48865_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

836617 : 936209

114

Streptococcus_phage(40.3%)

transposase,head,tRNA,capsid,portal,tail,integrase,terminase

attL 851428:851443|attR 873050:873065

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB61009.1\|836617_836842_-\|transposase	transposase	NA	NA	NA	NA
QBB61010.1\|837161_838421_+	extracellular solute-binding protein	NA	NA	NA	NA
QBB61011.1\|838586_840290_+	alpha-glycosidase	NA	NA	NA	NA
QBB61012.1\|840315_842451_+	cyclomaltodextrin glucanotransferase	NA	NA	NA	NA
QBB61013.1\|842525_843833_+	sugar ABC transporter permease	NA	NA	NA	NA
QBB61014.1\|843829_844690_+	sugar ABC transporter permease	NA	NA	NA	NA
QBB61015.1\|844711_845527_+	maltodextrose utilization protein malA	NA	NA	NA	NA
QBB61016.1\|845642_846443_-	LacI family transcriptional regulator	NA	NA	NA	NA
QBB61017.1\|846597_847434_-	sugar ABC transporter permease	NA	NA	NA	NA
QBB61018.1\|847433_848795_-	sugar ABC transporter permease	NA	NA	NA	NA
QBB61019.1\|849068_850316_-	extracellular solute-binding protein	NA	NA	NA	NA
QBB61020.1\|850558_851578_+	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
851428:851443	attL	NA	NA	NA	NA
QBB61021.1\|851693_853187_+	4-alpha-glucanotransferase	NA	NA	NA	NA
QBB61022.1\|853221_855486_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
QBB61023.1\|855742_856363_-	DUF3862 domain-containing protein	NA	NA	NA	NA
QBB61024.1\|856725_857814_-\|integrase	site-specific integrase	Q38159	Streptococcus_phage	3.0e-202	98.6
QBB61025.1\|858063_858873_-	MazF family toxin-antitoxin system	J7KDP1	Streptococcus_phage	2.9e-24	35.8
QBB61026.1\|858885_859629_-	helix-turn-helix domain-containing protein	A0A1S5S8T5	Streptococcus_phage	2.5e-75	62.9
QBB61027.1\|860121_860337_-	hypothetical protein	J7KBX0	Streptococcus_phage	2.5e-28	95.7
QBB61028.1\|860395_860554_+	hypothetical protein	J7KH24	Streptococcus_phage	8.4e-21	90.4
QBB61029.1\|860583_861183_-	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	3.1e-108	100.0
QBB61030.1\|861236_861446_+	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	1.7e-32	100.0
QBB61031.1\|861434_861821_-	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	1.2e-65	100.0
QBB61032.1\|861894_862122_+	XRE family transcriptional regulator	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
QBB61033.1\|862229_862739_-	hypothetical protein	NA	NA	NA	NA
QBB61034.1\|862793_863039_+	hypothetical protein	A0A097PAP6	Streptococcus_pyogenes_phage	1.2e-34	95.1
QBB61035.1\|862997_863207_-	hypothetical protein	NA	NA	NA	NA
QBB61036.1\|863356_863596_-	hypothetical protein	NA	NA	NA	NA
QBB61037.1\|863762_863948_+	XRE family transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
QBB61038.1\|864026_864323_+	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
QBB61039.1\|864319_864457_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
QBB61040.1\|864537_864867_+	hypothetical protein	J7KBZ0	Streptococcus_phage	7.9e-13	41.8
QBB61041.1\|864866_865061_+	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
QBB61042.1\|865057_865342_+	hypothetical protein	NA	NA	NA	NA
QBB61043.1\|865338_866022_+	DNA-binding protein	J7KC09	Streptococcus_phage	9.4e-125	99.1
QBB61044.1\|866057_867461_+	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.3
QBB61045.1\|867465_867948_+	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
QBB61046.1\|867965_869519_+	phage resistance protein	A0A1P8BM51	Lactococcus_phage	5.7e-210	70.6
QBB61047.1\|869787_870657_+	hypothetical protein	A0A1P8BME8	Lactococcus_phage	5.8e-103	65.6
QBB61048.1\|870610_870961_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	9.9e-46	88.5
QBB61049.1\|870944_871301_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
QBB61050.1\|871297_871543_+	hypothetical protein	A0A097PBE9	Streptococcus_pyogenes_phage	2.1e-39	95.1
QBB61051.1\|871542_871779_+	DUF3310 domain-containing protein	A0A097PAQ7	Streptococcus_pyogenes_phage	2.4e-40	100.0
QBB61052.1\|871942_872227_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
QBB61053.1\|872228_872861_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.1e-85	68.6
QBB62087.1\|872865_873345_+	DUF1642 domain-containing protein	A0A141E0J6	Streptococcus_phage	6.5e-24	41.9
873050:873065	attR	NA	NA	NA	NA
QBB61054.1\|873793_874228_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	6.2e-74	97.9
QBB61055.1\|874805_875720_+	hypothetical protein	NA	NA	NA	NA
QBB61056.1\|875738_876200_+	hypothetical protein	NA	NA	NA	NA
QBB61057.1\|876337_876715_-	HicB family protein	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
QBB61058.1\|876766_876952_-	addiction module toxin, HicA family	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
QBB62088.1\|877014_877482_+\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.1e-52	70.8
QBB61059.1\|877459_878767_+\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.0e-184	75.7
QBB61060.1\|878778_880281_+\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
QBB61061.1\|880261_881824_+\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	2.5e-48	44.2
QBB61062.1\|881827_882013_+	hypothetical protein	NA	NA	NA	NA
QBB61063.1\|882082_882397_+	hypothetical protein	M1PLI3	Streptococcus_phage	6.8e-38	72.8
QBB61064.1\|882399_882666_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.9e-25	70.5
QBB61065.1\|882809_883343_+	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	6.8e-14	80.7
QBB61066.1\|883352_883733_+\|head	head decoration protein	A0A0K2CNR0	Brevibacillus_phage	1.8e-05	32.5
QBB61067.1\|883735_884818_+\|capsid	minor capsid protein E	A0A2H4J022	uncultured_Caudovirales_phage	3.4e-105	57.1
QBB61068.1\|884827_885070_+	hypothetical protein	NA	NA	NA	NA
QBB61069.1\|885083_885437_+	hypothetical protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
QBB61070.1\|885433_885742_+	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	7.4e-13	40.2
QBB61071.1\|885722_886088_+	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	5.9e-17	46.3
QBB61072.1\|886084_886474_+\|capsid	phage capsid protein	B5SP36	Lactococcus_phage	4.2e-45	68.2
QBB62089.1\|886528_887152_+\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	3.2e-39	50.5
QBB61073.1\|887205_887559_+	hypothetical protein	Q77RZ7	Lactococcus_phage	5.5e-20	48.6
QBB62090.1\|887633_887930_+	hypothetical protein	A0A0S2MYH1	Enterococcus_phage	1.3e-09	42.2
QBB61074.1\|887944_891580_+\|tail	phage tail protein	C5IUK3	Streptococcus_phage	1.2e-85	41.4
QBB61075.1\|891611_892391_+\|tail	phage tail protein	A3F655	Streptococcus_phage	1.9e-65	54.0
QBB61076.1\|892387_894442_+	hypothetical protein	A3F656	Streptococcus_phage	0.0e+00	84.1
QBB61077.1\|894438_895653_+	hypothetical protein	A3F657	Streptococcus_phage	5.0e-44	49.5
QBB61078.1\|895639_895969_+	hypothetical protein	NA	NA	NA	NA
QBB61079.1\|895979_897875_+	hyaluronidase	Q938J9	Temperate_phage	5.9e-76	52.5
QBB61080.1\|897888_898050_+	hypothetical protein	NA	NA	NA	NA
QBB61081.1\|898052_898670_+	hypothetical protein	A3F662	Streptococcus_phage	9.8e-89	94.6
QBB61082.1\|898680_898977_+	hypothetical protein	Q938J6	Temperate_phage	3.7e-46	98.0
QBB61083.1\|898973_899159_+	hypothetical protein	Q938J5	Temperate_phage	6.6e-25	96.7
QBB61084.1\|899270_900605_+	lysin	Q5MY96	Streptococcus_phage	1.3e-247	93.0
QBB61085.1\|900680_901388_-	exotoxin type C	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
QBB61086.1\|901498_902257_-	DNAse	NA	NA	NA	NA
QBB61087.1\|902498_902687_+	Paratox	A3F673	Streptococcus_phage	2.1e-18	76.3
QBB61088.1\|903277_903892_+	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
QBB61089.1\|904018_904804_-	ABC transporter permease	NA	NA	NA	NA
QBB61090.1\|904813_905512_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
QBB61091.1\|905511_905883_-	GntR family transcriptional regulator	NA	NA	NA	NA
QBB61092.1\|906067_909178_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	5.4e-119	29.7
QBB61093.1\|909257_910271_+	6-phosphofructokinase	NA	NA	NA	NA
QBB61094.1\|910333_911836_+	pyruvate kinase	NA	NA	NA	NA
QBB61095.1\|912053_912611_+	signal peptidase I	NA	NA	NA	NA
QBB61096.1\|912786_914601_+	glutamine--fructose-6-phosphate aminotransferase	A7IW18	Paramecium_bursaria_Chlorella_virus	1.2e-97	38.7
QBB61097.1\|914796_915132_+	alkylphosphonate utilization protein	NA	NA	NA	NA
QBB61098.1\|915238_915880_+	amino acid ABC transporter permease	NA	NA	NA	NA
QBB61099.1\|915889_916519_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.8e-28	35.5
QBB61100.1\|916534_917371_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
QBB61101.1\|917740_918514_+	hypothetical protein	NA	NA	NA	NA
QBB61102.1\|918883_920119_-	cation diffusion facilitator family transporter	NA	NA	NA	NA
QBB61103.1\|920238_921561_-	sodium:alanine symporter family protein	NA	NA	NA	NA
QBB61104.1\|922089_924408_+	DNA helicase PcrA	A7KV33	Bacillus_phage	2.7e-131	41.2
QBB61105.1\|924770_925019_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
QBB61106.1\|925055_925667_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
QBB61107.1\|925677_925866_+	DUF2273 domain-containing protein	NA	NA	NA	NA
QBB61108.1\|925878_926418_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
QBB61109.1\|926458_926659_+	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
QBB61110.1\|926666_927158_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
QBB61111.1\|927320_927962_+	GntR family transcriptional regulator	NA	NA	NA	NA
QBB61112.1\|928104_928647_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
QBB61113.1\|928764_929466_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	37.0
QBB61114.1\|929480_932117_+	peptide ABC transporter permease	NA	NA	NA	NA
QBB61115.1\|932208_932805_+	restriction endonuclease subunit S	NA	NA	NA	NA
QBB61116.1\|932815_933772_+	aromatic acid exporter family protein	NA	NA	NA	NA
QBB61117.1\|933868_935209_+	DUF2130 domain-containing protein	NA	NA	NA	NA
QBB61118.1\|935324_936209_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA

DBSCAN-SWA_3

1256105 : 1266709

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB61412.1\|1256105_1257248_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3
QBB61413.1\|1257482_1257923_+	hypothetical protein	NA	NA	NA	NA
QBB61414.1\|1257952_1259221_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
QBB61415.1\|1259308_1260661_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.7
QBB61416.1\|1260882_1261224_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
QBB61417.1\|1261284_1262451_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
QBB61418.1\|1262544_1263231_-	3-dehydroquinase	W6LP76	Streptococcus_phage	7.0e-88	68.9
QBB61419.1\|1263227_1264391_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.5e-143	64.9
QBB61420.1\|1264498_1266709_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.5e-267	68.8

DBSCAN-SWA_4

1544814 : 1550688

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB61665.1\|1544814_1545642_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
QBB61666.1\|1545715_1546072_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
QBB61667.1\|1546370_1547000_+	copper homeostasis protein CutC	NA	NA	NA	NA
QBB61668.1\|1547046_1547439_-	hypothetical protein	NA	NA	NA	NA
QBB61669.1\|1547465_1548329_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
QBB61670.1\|1548333_1548657_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
QBB61671.1\|1549159_1550035_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
QBB61672.1\|1550052_1550688_-	thymidylate kinase	M1PSC7	Streptococcus_phage	2.7e-65	63.4

DBSCAN-SWA_5

1768073 : 1867341

113

Streptococcus_phage(80.0%)

head,capsid,protease,portal,tail,integrase,terminase,holin

attL 1850706:1850726|attR 1864642:1864662

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB61863.1\|1768073_1770518_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	7.0e-122	39.0
QBB61864.1\|1770517_1770979_-	CtsR family transcriptional regulator	NA	NA	NA	NA
QBB62118.1\|1771174_1771378_-	cold-shock protein	Q9AZD3	Lactococcus_phage	6.1e-24	80.0
QBB61865.1\|1771968_1773036_-\|integrase	site-specific integrase	A0A1P8VVR7	Streptococcus_phage	2.3e-170	83.7
QBB61866.1\|1773159_1773564_-	DUF4429 domain-containing protein	A0A1P8VVY3	Streptococcus_phage	2.4e-59	89.6
QBB61867.1\|1773585_1774332_-	ImmA/IrrE family metallo-endopeptidase	A0A0A0YSF3	Streptococcus_phage	1.6e-117	85.8
QBB61868.1\|1774340_1774721_-	XRE family transcriptional regulator	A0A0A0YV45	Streptococcus_phage	4.8e-46	71.4
QBB61869.1\|1775008_1775173_+	hypothetical protein	A0A1P8VVU2	Streptococcus_phage	1.8e-21	100.0
QBB61870.1\|1775155_1775626_-	hypothetical protein	A0A1P8VVS1	Streptococcus_phage	6.1e-83	100.0
QBB61871.1\|1775587_1775899_+	XRE family transcriptional regulator	A0A1P8VVQ4	Streptococcus_phage	2.1e-31	100.0
QBB61872.1\|1775898_1776240_+	hypothetical protein	A0A1P8VVU1	Streptococcus_phage	6.0e-56	100.0
QBB61873.1\|1776286_1776817_+	endonuclease	A0A1P8VVT6	Streptococcus_phage	1.3e-94	100.0
QBB61874.1\|1776816_1777101_+	DNA-binding protein	A0A1P8VVZ3	Streptococcus_phage	1.4e-50	100.0
QBB62119.1\|1777079_1777343_+	hypothetical protein	A0A1P8VVV1	Streptococcus_phage	3.9e-31	98.6
QBB61875.1\|1777351_1778683_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.7e-242	99.5
QBB61876.1\|1778684_1779287_+	hypothetical protein	A0A1P8VVT8	Streptococcus_phage	3.8e-114	100.0
QBB61877.1\|1779264_1780011_+	DNA replication protein	A0A1P8VVR3	Streptococcus_phage	1.1e-139	100.0
QBB61878.1\|1780011_1780833_+	ATP-binding protein	A0A1P8VVV9	Streptococcus_phage	1.2e-150	96.7
QBB61879.1\|1780832_1782146_+	DNA (cytosine-5-)-methyltransferase	A0A1S5SDI9	Streptococcus_phage	1.0e-167	74.8
QBB61880.1\|1782142_1782547_+	hypothetical protein	A0A1P8VVT9	Streptococcus_phage	2.3e-30	82.5
QBB61881.1\|1782539_1783031_+	hypothetical protein	A0A1P8VVP1	Streptococcus_phage	4.9e-83	95.7
QBB61882.1\|1783030_1783360_+	DUF1372 family protein	A0A1P8VVQ5	Streptococcus_phage	1.1e-54	94.5
QBB61883.1\|1783359_1783716_+	DUF3310 domain-containing protein	M1NRN1	Streptococcus_phage	6.5e-37	69.0
QBB61884.1\|1783712_1783919_+	hypothetical protein	A0A1P8VVV0	Streptococcus_phage	6.2e-32	100.0
QBB61885.1\|1783908_1784325_+	Single-stranded DNA-binding protein 4	A0A1P8VVS8	Streptococcus_phage	8.6e-73	100.0
QBB61886.1\|1784334_1784595_+	hypothetical protein	A0A1P8VVV2	Streptococcus_phage	9.9e-43	100.0
QBB61887.1\|1784579_1784939_+	XRE family transcriptional regulator	A0A1P8VVV5	Streptococcus_phage	4.1e-63	100.0
QBB61888.1\|1784935_1785400_+	hypothetical protein	A0A1P8VVT5	Streptococcus_phage	1.8e-82	100.0
QBB61889.1\|1785509_1786052_+\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	9.8e-101	100.0
QBB61890.1\|1786341_1786629_+	hypothetical protein	A0A1P8VVZ1	Streptococcus_phage	8.1e-46	98.9
QBB61891.1\|1786628_1786988_+	HNH endonuclease	A0A1P8VVU5	Streptococcus_phage	6.3e-64	100.0
QBB61892.1\|1787075_1787561_+	hypothetical protein	A0A1S5SCZ6	Streptococcus_phage	1.6e-78	97.5
QBB61893.1\|1787553_1789266_+\|terminase	terminase large subunit	A0A1P8VVW5	Streptococcus_phage	0.0e+00	100.0
QBB61894.1\|1789274_1790417_+\|portal	phage portal protein	A0A1P8VVT4	Streptococcus_phage	6.6e-216	100.0
QBB61895.1\|1790466_1791009_+\|head,protease	HK97 family phage prohead protease	A0A1P8VVX2	Streptococcus_phage	2.7e-98	100.0
QBB61896.1\|1791019_1792282_+\|capsid	phage major capsid protein	A0A1P8VVT0	Streptococcus_phage	9.9e-229	99.8
QBB61897.1\|1792302_1792638_+	hypothetical protein	A0A1P8VVS7	Streptococcus_phage	7.0e-57	100.0
QBB61898.1\|1792634_1792940_+\|head,tail	phage head-tail adapter protein	A0A1P8VVX4	Streptococcus_phage	1.4e-40	86.1
QBB61899.1\|1792939_1793287_+	hypothetical protein	A0A1P8VVS6	Streptococcus_phage	2.4e-60	99.1
QBB61900.1\|1793273_1793618_+	HK97 gp10 family phage protein	A0A1P8VVU6	Streptococcus_phage	1.3e-58	98.2
QBB61901.1\|1793632_1794316_+\|tail	phage tail protein	A0A1P8VVR1	Streptococcus_phage	9.1e-128	100.0
QBB61902.1\|1794315_1794792_+	hypothetical protein	A0A1P8VVU0	Streptococcus_phage	6.6e-85	98.7
QBB61903.1\|1794830_1794959_+	hypothetical protein	A0A0A0YRS9	Streptococcus_phage	1.6e-14	90.5
QBB61904.1\|1794977_1797713_+\|tail	phage tail tape measure protein	A0A1P8VVW8	Streptococcus_phage	2.8e-268	99.2
QBB61905.1\|1797709_1798432_+\|tail	phage tail protein	A0A1P8VVR4	Streptococcus_phage	1.1e-134	99.2
QBB61906.1\|1798432_1802107_+	hypothetical protein	A0A1P8VVT1	Streptococcus_phage	0.0e+00	98.9
QBB61907.1\|1802123_1802354_+	hypothetical protein	A0A1P8VVV7	Streptococcus_phage	4.2e-29	98.7
QBB61908.1\|1802356_1802695_+	hypothetical protein	A0A1P8VVU3	Streptococcus_phage	1.4e-60	97.3
QBB61909.1\|1802729_1803140_+	hypothetical protein	A0A1P8VVS2	Streptococcus_phage	2.0e-69	100.0
QBB61910.1\|1803142_1803472_+\|holin	phage holin	A0A1P8VVR0	Streptococcus_phage	4.8e-50	100.0
QBB61911.1\|1803475_1804882_+\|holin	holin	A0A1P8VVS3	Streptococcus_phage	5.8e-230	99.6
QBB61912.1\|1805088_1805274_+	type II toxin-antitoxin system HicA family toxin	A0A1P8VVU8	Streptococcus_phage	2.6e-29	100.0
QBB61913.1\|1805334_1805739_+	HicB family protein	A0A1P8VVW2	Streptococcus_phage	2.0e-66	99.3
QBB61914.1\|1806429_1806990_+	peroxiredoxin	NA	NA	NA	NA
QBB61915.1\|1807010_1808543_+	alkyl hydroperoxide reductase subunit F	A0A2I2L5E1	Orpheovirus	1.1e-43	37.5
QBB61916.1\|1808600_1809887_-	imidazolonepropionase	NA	NA	NA	NA
QBB61917.1\|1810157_1812188_+	urocanate hydratase	NA	NA	NA	NA
QBB61918.1\|1812275_1813175_+	glutamate formimidoyltransferase	NA	NA	NA	NA
QBB61919.1\|1813185_1813812_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
QBB61920.1\|1813829_1815503_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
QBB61921.1\|1815524_1816121_+	HutD family protein	NA	NA	NA	NA
QBB61922.1\|1816340_1817684_+	APC family permease	NA	NA	NA	NA
QBB61923.1\|1817694_1819236_+	histidine ammonia-lyase	A0A1V0S940	Catovirus	1.2e-98	43.4
QBB61924.1\|1819421_1820408_+	formimidoylglutamase	NA	NA	NA	NA
QBB61925.1\|1820438_1823513_-	LuxR family transcriptional regulator	NA	NA	NA	NA
QBB61926.1\|1823816_1824584_+	30S ribosomal protein S2	NA	NA	NA	NA
QBB61927.1\|1824717_1825758_+	elongation factor Ts	NA	NA	NA	NA
QBB61928.1\|1825923_1827819_-	endopeptidase	A0A1V0SHG2	Klosneuvirus	3.0e-72	28.7
QBB61929.1\|1828026_1829655_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
QBB61930.1\|1829722_1831747_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
QBB61931.1\|1831957_1832671_+	trehalose operon repressor	NA	NA	NA	NA
QBB61932.1\|1832765_1832894_-	GntR family transcriptional regulator	NA	NA	NA	NA
QBB61933.1\|1833473_1834331_+	VOC family protein	NA	NA	NA	NA
QBB61934.1\|1834372_1835104_+	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	9.6e-35	37.4
QBB61935.1\|1835277_1835892_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	1.5e-52	56.7
QBB61936.1\|1835891_1836401_-	GNAT family acetyltransferase	NA	NA	NA	NA
QBB61937.1\|1836409_1837345_-	gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
QBB61938.1\|1837701_1839900_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.0e-277	64.9
QBB61939.1\|1839996_1841556_-	DUF2079 domain-containing protein	NA	NA	NA	NA
QBB61940.1\|1841969_1842275_-	DUF1292 domain-containing protein	NA	NA	NA	NA
QBB61941.1\|1842286_1842706_-	Holliday junction resolvase RuvX	NA	NA	NA	NA
QBB61942.1\|1842702_1842972_-	IreB family regulatory phosphoprotein	NA	NA	NA	NA
QBB61943.1\|1843085_1843484_-	transcriptional regulator Spx	NA	NA	NA	NA
QBB61944.1\|1843774_1844911_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.4e-120	63.5
QBB61945.1\|1844999_1846271_-	competence/damage-inducible protein A	NA	NA	NA	NA
QBB61946.1\|1846339_1846900_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
QBB61947.1\|1846909_1847506_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
QBB61948.1\|1847507_1848728_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.6e-05	23.8
QBB62120.1\|1848738_1850721_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.3e-62	30.1
1850706:1850726	attL	NA	NA	NA	NA
QBB62121.1\|1850815_1851961_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	3.5e-84	44.9
QBB61949.1\|1852215_1852359_+\|holin	putative holin-like toxin	NA	NA	NA	NA
QBB61950.1\|1853220_1853988_-	helix-turn-helix domain-containing protein	Q76TK4	Streptococcus_pyogenes_phage	3.6e-72	83.1
QBB61951.1\|1854141_1854348_+	XRE family transcriptional regulator	X2KUC2	Streptococcus_phage	2.4e-07	47.0
QBB61952.1\|1854381_1854582_+	XRE family transcriptional regulator	A0A1S5SE31	Streptococcus_phage	3.4e-11	56.7
QBB61953.1\|1854602_1855010_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	1.3e-49	69.4
QBB61954.1\|1855421_1855949_+	hypothetical protein	R9QNB1	Lactococcus_phage	9.7e-21	40.2
QBB61955.1\|1856175_1856370_+	CopG family transcriptional regulator	NA	NA	NA	NA
QBB61956.1\|1856510_1856963_+	hypothetical protein	NA	NA	NA	NA
QBB61957.1\|1857064_1857397_+	hypothetical protein	NA	NA	NA	NA
QBB62122.1\|1857396_1857588_+	hypothetical protein	NA	NA	NA	NA
QBB61958.1\|1857599_1857929_+	hypothetical protein	NA	NA	NA	NA
QBB61959.1\|1857931_1858204_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.6e-19	60.0
QBB61960.1\|1858204_1859071_+	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	6.1e-121	73.8
QBB61961.1\|1859082_1860477_+	virulence-associated protein E	A0A1W6JQD6	Staphylococcus_phage	1.3e-48	38.1
QBB61962.1\|1860770_1861025_+	hypothetical protein	NA	NA	NA	NA
QBB61963.1\|1861021_1861195_+	DUF2758 domain-containing protein	A0A1X9I5U0	Streptococcus_phage	8.6e-11	59.6
QBB61964.1\|1861375_1861885_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.9e-29	63.5
QBB61965.1\|1861958_1862447_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
QBB61966.1\|1862671_1862854_+	hypothetical protein	NA	NA	NA	NA
QBB61967.1\|1862850_1863213_+	DUF1492 domain-containing protein	NA	NA	NA	NA
QBB61968.1\|1863187_1863571_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	3.7e-14	41.7
QBB61969.1\|1863735_1864389_+	hypothetical protein	NA	NA	NA	NA
QBB61970.1\|1864785_1867341_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	6.8e-43	22.8
1864642:1864662	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1893751 : 1903739

Streptococcus_phage(75.0%)

integrase

attL 1893325:1893339|attR 1900887:1900901

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1893325:1893339	attL	NA	NA	NA	NA
QBB62005.1\|1893751_1893925_-	DUF2758 domain-containing protein	A0A1X9I5U0	Streptococcus_phage	1.9e-10	59.6
QBB62006.1\|1894211_1895825_-	phage resistance protein	A0A1P8BMF9	Lactococcus_phage	2.4e-147	53.1
QBB62007.1\|1895814_1896336_-	hypothetical protein	NA	NA	NA	NA
QBB62008.1\|1896345_1896714_-	hypothetical protein	A0A1X9I6M4	Streptococcus_phage	2.6e-12	47.1
QBB62123.1\|1896622_1896814_-	hypothetical protein	NA	NA	NA	NA
QBB62009.1\|1896813_1897146_-	hypothetical protein	NA	NA	NA	NA
QBB62010.1\|1897157_1897340_-	hypothetical protein	NA	NA	NA	NA
QBB62011.1\|1897560_1897830_-	phage antirepressor protein	NA	NA	NA	NA
QBB62012.1\|1897859_1898426_-	phage repressor protein	A0A0A7S0G2	Clostridium_phage	5.0e-23	42.9
QBB62013.1\|1898441_1898630_-	XRE family transcriptional regulator	A0A1X9I5U7	Streptococcus_phage	1.7e-12	59.7
QBB62014.1\|1898798_1899242_+	XRE family transcriptional regulator	A0A1X9I723	Streptococcus_phage	1.8e-07	48.6
QBB62015.1\|1899421_1900585_+\|integrase	site-specific integrase	A0A1X9I6A9	Streptococcus_phage	2.8e-161	70.5
QBB62016.1\|1900741_1901353_-	30S ribosomal protein S4	NA	NA	NA	NA
1900887:1900901	attR	NA	NA	NA	NA
QBB62017.1\|1902082_1902355_-	hypothetical protein	NA	NA	NA	NA
QBB62018.1\|1902371_1903739_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.0e-154	63.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP031618

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection