CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP031625	Streptococcus pyogenes strain MGAS28533 chromosome, complete genome	3 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csn2,cas9,csm6,DinG,csa3	0	7	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP031625_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031625_1

604144-604306

TypeI

I-C

Consensus_repeat	Method
TAGTCTCACCCTTCATGGGTGAGTGGATTGAAA	PILER-CR

2 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of CP031625_1

>merge|CP031625|1|604144-604306|PILER-CR
AGTCTCACCCTTCATGGGTGAGTGGATTGAAATAAATAATTACATGACTAGCCAATACACCCACATAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTTCATGAGCTTCTTTACTCTCAAAGTAAGAGTGGTCTCACCCTTCATGGGTGAGTGGATTGAAA

>CP031625|1|1|604144-604306|PILER-CR
AGTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACAT
AGTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGT
GGTCTCACCCTTCATGGGTGAGTGGATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP031625.1\|QBB48401.1\|608877_609258_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753
CP031625.1\|QBB48395.1\|603702_603996_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
CP031625.1\|QBB48388.1\|593174_595823_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP031625.1\|QBB48398.1\|605855_606962_+\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|184456
CP031625.1\|QBB48394.1\|602666_603692_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
CP031625.1\|QBB48402.1\|609271_609631_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031625.1\|QBB48393.1\|601995_602670_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
CP031625.1\|QBB48403.1\|610426_610618_+\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB48389.1\|595976_598385_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP031625.1\|QBB48390.1\|598517_599246_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
CP031625.1\|QBB48397.1\|605189_605813_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
CP031625.1\|QBB48400.1\|608345_608867_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB48405.1\|611535_611736_-\|KTSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|379296
CP031625.1\|QBB48387.1\|592609_593173_+\|shikimate-kinase	unknown	unknown	unknown
CP031625.1\|QBB48404.1\|610628_611357_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|226091
CP031625.1\|QBB48396.1\|604466_605177_+\|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl\|CDD\|223856
CP031625.1\|QBB48392.1\|601145_601994_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
CP031625.1\|QBB48391.1\|599245_601141_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|273839
CP031625.1\|QBB48399.1\|607072_608227_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP031625.1\|QBB48386.1\|592433_592613_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584

Protein	Function_ID	Function_description	E-value
CP031625.1\|QBB48401.1\|608877_609258_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00284034
CP031625.1\|QBB48397.1\|605189_605813_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.08316e-34
CP031625.1\|QBB48388.1\|593174_595823_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
CP031625.1\|QBB48398.1\|605855_606962_+\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	3.04644e-163
CP031625.1\|QBB48395.1\|603702_603996_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
CP031625.1\|QBB48393.1\|601995_602670_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	3.0744e-43
CP031625.1\|QBB48389.1\|595976_598385_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.76387e-159
CP031625.1\|QBB48390.1\|598517_599246_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.32713e-117
CP031625.1\|QBB48399.1\|607072_608227_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.16705e-43
CP031625.1\|QBB48405.1\|611535_611736_-\|KTSC-domain-containing-protein	gnl\|CDD\|379296	pfam13619, KTSC, KTSC domain. This short domain is named after Lysine tRNA synthetase C-terminal domain. It is found at the C-terminus of some Lysyl tRNA synthetases as well as a single domain in bacterial proteins. The domain is about 60 amino acids in length and contains a reasonably conserved YXY motif in the centre of the sequence. The function of this domain is unknown but it could be an RNA binding domain.	5.60317e-09
CP031625.1\|QBB48394.1\|602666_603692_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
CP031625.1\|QBB48404.1\|610628_611357_+\|oxidoreductase	gnl\|CDD\|226091	COG3561, COG3561, Phage anti-repressor protein [Transcription].	2.15147e-42
CP031625.1\|QBB48396.1\|604466_605177_+\|cytochrome-c-biogenesis-protein-CcdA	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	2.85986e-42
CP031625.1\|QBB48392.1\|601145_601994_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	2.68212e-160
CP031625.1\|QBB48391.1\|599245_601141_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
CP031625.1\|QBB48402.1\|609271_609631_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.27575e-08
CP031625.1\|QBB48386.1\|592433_592613_+\|N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	3.61304e-12

>CP031625.1|QBB48395.1|603702_603996_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>CP031625.1|QBB48394.1|602666_603692_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>CP031625.1|QBB48393.1|601995_602670_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>CP031625.1|QBB48392.1|601145_601994_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>CP031625.1|QBB48391.1|599245_601141_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMLKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSEFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>CP031625.1|QBB48390.1|598517_599246_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>CP031625.1|QBB48389.1|595976_598385_+|CRISPR-associated-helicase/endonuclease-Cas3
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>CP031625.1|QBB48388.1|593174_595823_+|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIVRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQAKYDATQERIAEMKKIKS
>CP031625.1|QBB48387.1|592609_593173_+|shikimate-kinase
MNLIIIGAQASGKMTIEQEVARQTGMNLFHNHDSIDFVLRFMPWSQESTALIERMRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>CP031625.1|QBB48386.1|592433_592613_+|N-acetyltransferase
MHKIELGCYDYNKQSQAVARKLGFTLEANVRERKDVQGRRCGGMRFGLLRSEWEEQKQK
>CP031625.1|QBB48396.1|604466_605177_+|cytochrome-c-biogenesis-protein-CcdA
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHIFLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>CP031625.1|QBB48397.1|605189_605813_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMVKKEITQDKMSMAVKKKDKMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>CP031625.1|QBB48398.1|605855_606962_+|peptide-methionine-(R)-S-oxide-reductase
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>CP031625.1|QBB48399.1|607072_608227_-|site-specific-integrase
MPISYLKISTPQRKERGKTMIEKYTKKDGTTAYRLRAYLGVDPVTGKQVRTTRQGFKTEREAKRAEVKLIDDFQRQGAWKSNDKTTFDDVAKLWFEQYQNTVKPSTFLVNQNYYKTILKPHLGQLQMTKITVMICQKFVNCLSRYSGYTLYLSLANRIFKFAVNLGIIDNNPMNKTLRSKCTYKNVDTLTKKYYTKEELNTFLRLVEAEETLEMRLIYRLLSYGGFRIGELIALKDTDFDFRNNTISITKTIAYTKEGWAVQSPKTKKSNRTISMDAETMSLAKLYIKQSIKPLHGSFKLFNFASDTVRKRLDRFILKHGLKRITPHGFRHTHASLLFEAGIPAKIAQERLGHAKIAITMDLYTHLSKKSKDNVADKLAELVAI
>CP031625.1|QBB48400.1|608345_608867_-|hypothetical-protein
MKKIVYLFTLSVLIVCLGACTGGSKKDTTSKTPSSDTSKVSGDMSEKEYFDTLISKIDKVTTDNYKSDEYLFYDYKTILRDPKKYFSLKVRINNLKIIQISDKDKYTKMLANTPNGDLYMLFIETKRLETKLLETDNITINGRYLLSYEYTTTSGSENSVPLIYIDGYLLLDK
>CP031625.1|QBB48401.1|608877_609258_-|ImmA/IrrE-family-metallo-endopeptidase
MMTPETVCQEKGIDLVYFDGRGTNIPGMFNKKHNVIAIDTYLDGIYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQFMEKYELTSIADEVMVKEEFKNLI
>CP031625.1|QBB48402.1|609271_609631_-|XRE-family-transcriptional-regulator
MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTANTDPIEKIANYFNVSTDYLLGRTDNPKMAQDGHTSVAIDLKKDAEETFFFDGHELNDEDIDLITSILETRIKNRK
>CP031625.1|QBB48403.1|610426_610618_+|hypothetical-protein
MPDNAIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRKKDPASNRFVLKVISDLKIR
>CP031625.1|QBB48404.1|610628_611357_+|oxidoreductase
MNNLITVTLNENQEPIVSGRDLHQALEIKTQYTKWLERMSDYGFEENEDYVAISQKRLTAQGNQTEYTDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSPEKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGVNIGQNKLFQWLRANGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKVTGKGQQYFINKFFNQEYLPV
>CP031625.1|QBB48405.1|611535_611736_-|KTSC-domain-containing-protein
MQRQYVSSSNARSVDWENNTLEVEFNNGSIYHYHNVSQTEYRSVLVGSVGSNIHRLAKIHTYTRIV

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Crispr_ID: CP031625_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031625_2

1098093-1098392

TypeII

II-A

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	PILER-CR

4 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP031625_2

>merge|CP031625|2|1098093-1098392|CRISPRCasFinder,CRT,PILER-CR
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAACGGAAAGCAGGAGAAAGGACGTTAATATGTCGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACGTCAAACTCAATTTTTTGTCTAGCTCTATTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAGACAAAAGAAAAAGCATTGTCAATTTCTAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAATAATCAGTTTAAAAATCCATCTGGAGCAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031625|2|1|1098093-1098392|CRISPRCasFinder
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAAC	GGAAAGCAGGAGAAAGGACGTTAATATGTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031625|2|1|1098093-1098392|CRT
GAATGGAGACCATTCAAAACAGCATAGCTCTAAAAC	GGAAAGCAGGAGAAAGGACGTTAATATGTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>CP031625|2|2|1098159-1098392|PILER-CR
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	GTCAAACTCAATTTTTTGTCTAGCTCTATT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGACAAAAGAAAAAGCATTGTCAATTTCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AATAATCAGTTTAAAAATCCATCTGGAGCA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP031625.1\|QBB48898.1\|1104904_1105537_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
CP031625.1\|QBB48895.1\|1099146_1099488_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP031625.1\|QBB48892.1\|1096701_1096806_-\|exfoliative-toxin	unknown	unknown	unknown
CP031625.1\|QBB48887.1\|1090335_1090827_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
CP031625.1\|QBB48903.1\|1109020_1110376_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
CP031625.1\|QBB48888.1\|1090845_1091271_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
CP031625.1\|QBB49662.1\|1093249_1094518_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
CP031625.1\|QBB48886.1\|1089509_1090319_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
CP031625.1\|QBB48885.1\|1088685_1089513_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
CP031625.1\|QBB48890.1\|1092626_1093064_-\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692
CP031625.1\|QBB48896.1\|1099484_1100354_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP031625.1\|QBB48899.1\|1105536_1106301_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
CP031625.1\|QBB48902.1\|1108255_1108897_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB48893.1\|1096810_1097944_-\|ISAs1-like-element-IS1548-family-transposase	unknown	unknown	gnl\|CDD\|227720
CP031625.1\|QBB48901.1\|1107062_1108193_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP031625.1\|QBB48889.1\|1091477_1092497_-\|putative-sulfate-exporter-family-transporter	unknown	unknown	gnl\|CDD\|225411
CP031625.1\|QBB48891.1\|1094809_1096642_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP031625.1\|QBB48894.1\|1098494_1099157_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP031625.1\|QBB48900.1\|1106300_1107053_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
CP031625.1\|QBB48897.1\|1100353_1104460_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044

Protein	Function_ID	Function_description	E-value
CP031625.1\|QBB48898.1\|1104904_1105537_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.04206e-87
CP031625.1\|QBB48895.1\|1099146_1099488_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.79e-58
CP031625.1\|QBB48887.1\|1090335_1090827_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
CP031625.1\|QBB48903.1\|1109020_1110376_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
CP031625.1\|QBB48888.1\|1090845_1091271_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	1.16501e-30
CP031625.1\|QBB49662.1\|1093249_1094518_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	5.56579e-11
CP031625.1\|QBB48886.1\|1089509_1090319_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
CP031625.1\|QBB48885.1\|1088685_1089513_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
CP031625.1\|QBB48890.1\|1092626_1093064_-\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	5.00558e-84
CP031625.1\|QBB48896.1\|1099484_1100354_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.48912e-131
CP031625.1\|QBB48899.1\|1105536_1106301_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.84127e-128
CP031625.1\|QBB48893.1\|1096810_1097944_-\|ISAs1-like-element-IS1548-family-transposase	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	1.29021e-30
CP031625.1\|QBB48901.1\|1107062_1108193_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP031625.1\|QBB48889.1\|1091477_1092497_-\|putative-sulfate-exporter-family-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	3.12379e-103
CP031625.1\|QBB48891.1\|1094809_1096642_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP031625.1\|QBB48894.1\|1098494_1099157_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.6851e-120
CP031625.1\|QBB48900.1\|1106300_1107053_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.21279e-109
CP031625.1\|QBB48897.1\|1100353_1104460_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0

>CP031625.1|QBB48893.1|1096810_1097944_-|ISAs1-like-element-IS1548-family-transposase
MIDFIISIDDCAVELDSRQSWKIGYPLSTILFLVFVCQLAGIETWKEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNTDRLKELKVQFEQSLTSLDAVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNFIRKMCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG
>CP031625.1|QBB48892.1|1096701_1096806_-|exfoliative-toxin
MIDLKRNLFKIDVRAQKDEEKVFMRTAWIIRKKR
>CP031625.1|QBB48891.1|1094809_1096642_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
>CP031625.1|QBB49662.1|1093249_1094518_-|LPXTG-cell-wall-anchor-domain-containing-protein
MLTFGGASAVKADEQEEKAKVRTELIQELAQGLGGIEKKNFPTLGDEDLDHTYMTKLLTYLQEREQAENSWRKRLLKGIQDHALDGQDGRNGERGEQGPTGPTGPAGPRGLQGLQGERGEQGPTGPTGPAGPRGLQGERGEQGPTGLAGKAGEAGAKGETGPAGPQGPRGEQGPQGLPGKDGEAGAQGPAGPMGPAGERGEKGEPGTQGAKGDRGETGPVGPRGERGEAGPAGKDGERGPVGPAGKDGQNGQDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGLPGKDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>CP031625.1|QBB48890.1|1092626_1093064_-|peptide-methionine-(R)-S-oxide-reductase
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET
>CP031625.1|QBB48889.1|1091477_1092497_-|putative-sulfate-exporter-family-transporter
MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNDGFATFAGTAVNDTSSVTATATAWDALHHSNTLDDATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVSADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>CP031625.1|QBB48888.1|1090845_1091271_-|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDNFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD
>CP031625.1|QBB48887.1|1090335_1090827_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>CP031625.1|QBB48886.1|1089509_1090319_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>CP031625.1|QBB48885.1|1088685_1089513_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>CP031625.1|QBB48894.1|1098494_1099157_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSELKFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>CP031625.1|QBB48895.1|1099146_1099488_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>CP031625.1|QBB48896.1|1099484_1100354_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVKSQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTLFGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKALNNEGKGVPEFRI
>CP031625.1|QBB48897.1|1100353_1104460_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRLNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKVLTRSDKNRGKSNNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIVKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATFIHQSITGLYETRIDLSQLGGD
>CP031625.1|QBB48898.1|1104904_1105537_-|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>CP031625.1|QBB48899.1|1105536_1106301_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>CP031625.1|QBB48900.1|1106300_1107053_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGGLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKPHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>CP031625.1|QBB48901.1|1107062_1108193_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>CP031625.1|QBB48902.1|1108255_1108897_-|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQENLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSRP
>CP031625.1|QBB48903.1|1109020_1110376_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

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Crispr_ID: CP031625_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031625_3

1851247-1851343

Orphan

Consensus_repeat	Method
AAAAACCCAATTTTTTTTCGTCTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP031625_3

>merge|CP031625|3|1851247-1851343|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTATTTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGTCAAGATAAAAATCCAATTTTTTTTCGTCTTAT

>CP031625|3|2|1851247-1851343|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTAT	TTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGTCAAGAT
AAAAATCCAATTTTTTTTCGTCTTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP031625.1\|QBB49580.1\|1850460_1851027_-\|phage-repressor-protein	unknown	unknown	gnl\|CDD\|226144
CP031625.1\|QBB49581.1\|1851042_1851231_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031625.1\|QBB49582.1\|1851399_1851843_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031625.1\|QBB49586.1\|1854972_1856340_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|180232
CP031625.1\|QBB49577.1\|1849414_1849747_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB49575.1\|1848415_1848937_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB49588.1\|1856818_1858795_-\|DHH-family-phosphoesterase	unknown	unknown	gnl\|CDD\|226404
CP031625.1\|QBB49589.1\|1858884_1860783_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
CP031625.1\|QBB49590.1\|1860906_1861224_-\|phosphohydrolase	unknown	unknown	gnl\|CDD\|240044
CP031625.1\|QBB49591.1\|1861999_1863121_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
CP031625.1\|QBB49585.1\|1854683_1854956_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226872
CP031625.1\|QBB49587.1\|1856369_1856822_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
CP031625.1\|QBB49583.1\|1852022_1853186_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
CP031625.1\|QBB49578.1\|1849758_1849941_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB49579.1\|1850161_1850431_-\|phage-antirepressor-protein	unknown	unknown	unknown
CP031625.1\|QBB49576.1\|1848946_1849315_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB49573.1\|1846352_1846526_-\|DUF2758-domain-containing-protein	unknown	unknown	unknown
CP031625.1\|QBB49689.1\|1849223_1849415_-\|hypothetical-protein	unknown	unknown	unknown
CP031625.1\|QBB49584.1\|1853342_1853954_-\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
CP031625.1\|QBB49574.1\|1846812_1848426_-\|phage-resistance-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP031625.1\|QBB49580.1\|1850460_1851027_-\|phage-repressor-protein	gnl\|CDD\|226144	COG3617, COG3617, Prophage antirepressor [Transcription].	1.58213e-27
CP031625.1\|QBB49581.1\|1851042_1851231_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00222954
CP031625.1\|QBB49582.1\|1851399_1851843_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.81587e-06
CP031625.1\|QBB49586.1\|1854972_1856340_-\|replicative-DNA-helicase	gnl\|CDD\|180232	PRK05748, PRK05748, replicative DNA helicase; Provisional.	0
CP031625.1\|QBB49591.1\|1861999_1863121_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
CP031625.1\|QBB49588.1\|1856818_1858795_-\|DHH-family-phosphoesterase	gnl\|CDD\|226404	COG3887, COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms].	0
CP031625.1\|QBB49589.1\|1858884_1860783_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
CP031625.1\|QBB49590.1\|1860906_1861224_-\|phosphohydrolase	gnl\|CDD\|240044	cd04688, Nudix_Hydrolase_29, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	7.82374e-17
CP031625.1\|QBB49585.1\|1854683_1854956_-\|hypothetical-protein	gnl\|CDD\|226872	COG4466, Veg, Uncharacterized protein conserved in bacteria [Function unknown].	7.52485e-33
CP031625.1\|QBB49587.1\|1856369_1856822_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	1.02239e-55
CP031625.1\|QBB49583.1\|1852022_1853186_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.50808e-45
CP031625.1\|QBB49584.1\|1853342_1853954_-\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	8.00838e-118

>CP031625.1|QBB49581.1|1851042_1851231_-|XRE-family-transcriptional-regulator
MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNYKAPKRIYASVMEWLAEDY
>CP031625.1|QBB49580.1|1850460_1851027_-|phage-repressor-protein
MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRARDVAEMIDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEHGLYEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDIDDLSYIKQKLTDLQDVDSLQDLRWKMAKLYHVIETLDEY
>CP031625.1|QBB49579.1|1850161_1850431_-|phage-antirepressor-protein
MRTDKGEMIMKATTYKELKKWIDEGVDLAELAQGYADKVPSVDREQFEAVTQGIFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY
>CP031625.1|QBB49578.1|1849758_1849941_-|hypothetical-protein
MTSVRTAQLLNNGLGLVGQDLKDVLSALANSVNPSIEKQISHIMIDRANTGEWLANVGKK
>CP031625.1|QBB49577.1|1849414_1849747_-|hypothetical-protein
MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQHIAWVIIANVMTEYVNKFRKSATSFEKAWDALGYQQTTEIVFRAVNGLPCSEKDTGELETYLSEVSA
>CP031625.1|QBB49689.1|1849223_1849415_-|hypothetical-protein
MQELNLTPTQTLILFIVLGLVGLLLSLSKPLIEIDLPEDTQVPKPPQNANYGAYIQSQNHYYN
>CP031625.1|QBB49576.1|1848946_1849315_-|hypothetical-protein
MTYQKIPKYLNHLRTQTMGLIFNHRTIITIRREQMQLLSREAELELLEKVGCYLEKRWQLELENKDDWDLIPRQDLLEKLDITGTTLKNWEKEGLKSYQSPFENSKKVYYRKSDIYNFLSVD
>CP031625.1|QBB49575.1|1848415_1848937_-|hypothetical-protein
MDYLEVTMTKDCVKIFNFLYKYPTKAYQKDEYFKLLYMHPLDSFLTSFSLSGIRVKVTDKPVLAGWKLVRDIEVRIATGELLEMIEELEICYLRKHQTVSYVEIKFYVVHLLTYGIRSRYDMQFFTKLLFCCGYDQETVIGIYSNITKNTRLSRDFITLQAKLYQTKKGTHEH
>CP031625.1|QBB49574.1|1846812_1848426_-|phage-resistance-protein
MSIKENIDKLVSMEWTESIFGQSKMKADYKRQLSKVIELDTLSNIHHNGETYAVSNQEVMYLSESKGRTHKFISGNVKTKSKGKGRDSQKYLVVSFDHQFPPFAKLVVDYLLGRFTFFNNKLYDVNNRQAQVLDDFTIQSLYGFKKDNPFILEILEGIHQTLNIRPAKQLEAYKISGRDFIIDLKEHRLYRTNPSSDSSFFKFYDVDYHTAIGSKKKVGKFLDYVIADHDSLHNATLQAYYIAQVACGLKSKQNFFISKSGVRTGKGLRHIGLSGIFNKIDVELDLLIKGGFEASNAWGAFAGGEMALATEQGDIVGDKMERVLKIIATEKTHMARSIGGNLGTVNLTSVLCIDTNRTVALSDEMNGRAVLIQYQNRPEGETDLEREKAFEEYWQTFTEMDKSPKIEGVIGFLLVSLDYFRKNDMKFDWRAVEVVNDDDLDDFQVYLINHLSEKDFVERDSYVRELYNSTYGKNNNQAGQRMRTIGVKSYRKQTTGGRKIPGYKVDNIKRFNKFSGGEKENTNIFDMFEKLNQPLPP
>CP031625.1|QBB49573.1|1846352_1846526_-|DUF2758-domain-containing-protein
MKIKLFYQKHNESLDDFEYRVNQFTLSVSVIDIKLSEATYGNYEDMSTTTSLLVLYR
>CP031625.1|QBB49582.1|1851399_1851843_+|XRE-family-transcriptional-regulator
MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENPKNTIKPDKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFSFDMTATESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP
>CP031625.1|QBB49583.1|1852022_1853186_+|site-specific-integrase
MNIKEYKKKNGTIIYRTSVYLGVDQVTGKKARTTITASTKKGVKIKARDALNNFAMNGYTVKEKPTVTTYKELTALWWESYKNTIKPNSRQSMEGIVRLHILPAFGDCKLSKLTTPVIQQQVNKWANNANKGIKGAYANYSFLNNINRRILQYGVTMQVIEHNPARDVIIPRKQNNKEHKVKFFSNQELKQFLNYLDDLDLSSYENFFDYVLYKTLLATGCRIGEVLALEWSDIDLKKGTIKVSKTLNRYQETNTPKSKAGLRDIEIDRATVLLLKQYKNRQQVLSWDLGRSETIVFTPFTTKYAYACLLRKRLQKHFKAAGVPDISFHGFRHTHATIMLYAGIEAKDLQYRLGHSNISMTLNTYVHATKEGAKKAVSIFETAISNL
>CP031625.1|QBB49584.1|1853342_1853954_-|30S-ribosomal-protein-S4
MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
>CP031625.1|QBB49585.1|1854683_1854956_-|hypothetical-protein
MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRLIEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD
>CP031625.1|QBB49586.1|1854972_1856340_-|replicative-DNA-helicase
MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER
>CP031625.1|QBB49587.1|1856369_1856822_-|50S-ribosomal-protein-L9
MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLTITEA
>CP031625.1|QBB49588.1|1856818_1858795_-|DHH-family-phosphoesterase
MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLLFVVALLWYQKEAYHLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNPYAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSFVGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFYRRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQIGQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDRIKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDFPDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTSRTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLYSNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFNLAACQLTDISLPQAKHLLLKTINMTMKETGEVES
>CP031625.1|QBB49589.1|1858884_1860783_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
>CP031625.1|QBB49590.1|1860906_1861224_-|phosphohydrolase
MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVGIRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSINWIK
>CP031625.1|QBB49591.1|1861999_1863121_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448767	Streptococcus phage Javan467, complete genome	17890-17919	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448685	Streptococcus phage Javan155, complete genome	18198-18227	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448771	Streptococcus phage Javan481, complete genome	17415-17444	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448829	Streptococcus phage Javan7, complete genome	19776-19805	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448736	Streptococcus phage Javan35, complete genome	20259-20288	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448781	Streptococcus phage Javan5, complete genome	22281-22310	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK449012	Streptococcus phage Javan94, complete genome	19127-19156	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	17995-18024	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448969	Streptococcus phage Javan514, complete genome	19138-19167	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MH853355	Streptococcus phage LF1, complete genome	10633-10662	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448964	Streptococcus phage Javan502, complete genome	17719-17748	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448943	Streptococcus phage Javan450, complete genome	17890-17919	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448972	Streptococcus phage Javan520, complete genome	17264-17293	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448938	Streptococcus phage Javan44, complete genome	20260-20289	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448855	Streptococcus phage Javan150, complete genome	18394-18423	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448786	Streptococcus phage Javan509, complete genome	17890-17919	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448774	Streptococcus phage Javan487, complete genome	16251-16280	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448963	Streptococcus phage Javan498, complete genome	13512-13541	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448773	Streptococcus phage Javan485, complete genome	19137-19166	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448911	Streptococcus phage Javan34, complete genome	20259-20288	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448837	Streptococcus phage Javan10, complete genome	18305-18334	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448742	Streptococcus phage Javan37, complete genome	20096-20125	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MH853358	Streptococcus phage LF4, complete genome	10633-10662	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448845	Streptococcus phage Javan118, complete genome	18668-18697	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448916	Streptococcus phage Javan36, complete genome	20259-20288	0	1.0
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448853	Streptococcus phage Javan144, complete genome	18198-18227	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448871	Streptococcus phage Javan196, complete genome	33084-33113	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448697	Streptococcus phage Javan185, complete genome	33084-33113	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448693	Streptococcus phage Javan177, complete genome	33084-33113	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448772	Streptococcus phage Javan483, complete genome	32792-32821	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448696	Streptococcus phage Javan183, complete genome	33084-33113	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	NC_009819	Streptococcus phage P9, complete genome	32033-32062	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448793	Streptococcus phage Javan523, complete genome	33428-33457	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448868	Streptococcus phage Javan188, complete genome	33085-33114	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448866	Streptococcus phage Javan184, complete genome	33084-33113	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448954	Streptococcus phage Javan476, complete genome	31815-31844	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448699	Streptococcus phage Javan189, complete genome	33084-33113	0	1.0
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448867	Streptococcus phage Javan186, complete genome	33084-33113	0	1.0
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448775	Streptococcus phage Javan489, complete genome	25298-25327	0	1.0
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448794	Streptococcus phage Javan525, complete genome	22421-22450	0	1.0
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448953	Streptococcus phage Javan474, complete genome	27019-27048	0	1.0
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448765	Streptococcus phage Javan459, complete genome	22420-22449	0	1.0
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448957	Streptococcus phage Javan484, complete genome	27899-27928	0	1.0
CP031625_2	2.4\|1098327\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098327-1098356	30	MK448662	Streptococcus satellite phage Javan97, complete genome	6081-6110	0	1.0
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448522	Streptococcus satellite phage Javan519, complete genome	1870-1914	0	1.0
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448330	Streptococcus satellite phage Javan136, complete genome	2770-2814	0	1.0
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448328	Streptococcus satellite phage Javan130, complete genome	2770-2814	0	1.0
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448513	Streptococcus satellite phage Javan479, complete genome	1870-1914	0	1.0
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448332	Streptococcus satellite phage Javan142, complete genome	2777-2821	0	1.0
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448331	Streptococcus satellite phage Javan138, complete genome	2777-2821	0	1.0
CP031625_1	1.1\|604177\|33\|CP031625\|PILER-CR	604177-604209	33	MK448762	Streptococcus phage Javan447, complete genome	57-89	1	0.97
CP031625_1	1.1\|604177\|33\|CP031625\|PILER-CR	604177-604209	33	MK448798	Streptococcus phage Javan533, complete genome	57-89	1	0.97
CP031625_1	1.1\|604177\|33\|CP031625\|PILER-CR	604177-604209	33	MK448793	Streptococcus phage Javan523, complete genome	57-89	1	0.97
CP031625_1	1.1\|604177\|33\|CP031625\|PILER-CR	604177-604209	33	MK448967	Streptococcus phage Javan510, complete genome	57-89	1	0.97
CP031625_1	1.1\|604177\|33\|CP031625\|PILER-CR	604177-604209	33	MK448954	Streptococcus phage Javan476, complete genome	57-89	1	0.97
CP031625_1	1.1\|604177\|33\|CP031625\|PILER-CR	604177-604209	33	NC_004588	Streptococcus prophage 315.5, complete genome	206-238	1	0.97
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448771	Streptococcus phage Javan481, complete genome	6936-6967	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448681	Streptococcus phage Javan141, complete genome	6534-6565	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448944	Streptococcus phage Javan452, complete genome	11200-11231	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448672	Streptococcus phage Javan117, complete genome	6782-6813	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448849	Streptococcus phage Javan128, complete genome	6685-6716	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448774	Streptococcus phage Javan487, complete genome	6921-6952	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448958	Streptococcus phage Javan486, complete genome	9165-9196	1	0.969
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448742	Streptococcus phage Javan37, complete genome	9157-9188	1	0.969
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448946	Streptococcus phage Javan456, complete genome	36512-36541	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448779	Streptococcus phage Javan497, complete genome	31741-31770	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448795	Streptococcus phage Javan527, complete genome	38519-38548	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448944	Streptococcus phage Javan452, complete genome	35553-35582	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448968	Streptococcus phage Javan512, complete genome	31741-31770	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	NC_004584	Streptococcus prophage 315.1, complete genome	31585-31614	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448797	Streptococcus phage Javan531, complete genome	31741-31770	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448978	Streptococcus phage Javan532, complete genome	31479-31508	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448785	Streptococcus phage Javan507, complete genome	31480-31509	1	0.967
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	NC_004589	Streptococcus prophage 315.6, complete genome	31838-31867	1	0.967
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448946	Streptococcus phage Javan456, complete genome	26948-26977	1	0.967
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448333	Streptococcus satellite phage Javan145, complete genome	2769-2813	1	0.978
CP031625_3	3.1\|1851273\|45\|CP031625\|CRISPRCasFinder	1851273-1851317	45	MK448340	Streptococcus satellite phage Javan156, complete genome	2769-2813	1	0.978
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448767	Streptococcus phage Javan467, complete genome	6874-6905	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448973	Streptococcus phage Javan522, complete genome	8841-8872	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448862	Streptococcus phage Javan178, complete genome	6910-6941	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448942	Streptococcus phage Javan448, complete genome	6873-6904	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK449010	Streptococcus phage Javan90, complete genome	9369-9400	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK449012	Streptococcus phage Javan94, complete genome	8203-8234	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	6979-7010	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448969	Streptococcus phage Javan514, complete genome	9629-9660	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448943	Streptococcus phage Javan450, complete genome	6874-6905	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448972	Streptococcus phage Javan520, complete genome	6683-6714	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448786	Streptococcus phage Javan509, complete genome	6874-6905	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448778	Streptococcus phage Javan493, complete genome	8856-8887	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448963	Streptococcus phage Javan498, complete genome	3463-3494	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448773	Streptococcus phage Javan485, complete genome	9629-9660	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448851	Streptococcus phage Javan14, complete genome	12142-12173	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448833	Streptococcus phage Javan87, complete genome	9369-9400	2	0.938
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448673	Streptococcus phage Javan119, complete genome	9948-9979	2	0.938
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448755	Streptococcus phage Javan423, complete genome	19783-19812	2	0.933
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	MK448756	Streptococcus phage Javan425, complete genome	19783-19812	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448771	Streptococcus phage Javan481, complete genome	26991-27020	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448942	Streptococcus phage Javan448, complete genome	18422-18451	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448794	Streptococcus phage Javan525, complete genome	32018-32047	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448964	Streptococcus phage Javan502, complete genome	27279-27308	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	M19348	Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds	511-540	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448951	Streptococcus phage Javan470, complete genome	32170-32199	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448765	Streptococcus phage Javan459, complete genome	32016-32045	2	0.933
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448764	Streptococcus phage Javan457, complete genome	25122-25151	2	0.933
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MK448933	Streptococcus phage Javan420, complete genome	26823-26852	2	0.933
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448964	Streptococcus phage Javan502, complete genome	6853-6884	3	0.906
CP031625_2	2.1\|1098129\|30\|CP031625\|CRISPRCasFinder,CRT	1098129-1098158	30	NC_028666	Streptococcus phage Str-PAP-1, complete genome	24240-24269	3	0.9
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	NZ_CP020429	Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence	100887-100918	4	0.875
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	NZ_CP020439	Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence	133702-133733	4	0.875
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	NZ_CP018188	Streptococcus salivarius strain ICDC2 plasmid, complete sequence	108973-109004	4	0.875
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	18924-18955	4	0.875
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MN480763	Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence	119912-119943	4	0.875
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448698	Streptococcus phage Javan187, complete genome	27333-27362	4	0.867
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448845	Streptococcus phage Javan118, complete genome	8663-8694	5	0.844
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448767	Streptococcus phage Javan467, complete genome	27472-27501	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	27577-27606	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448976	Streptococcus phage Javan528, complete genome	32036-32065	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448943	Streptococcus phage Javan450, complete genome	27472-27501	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448972	Streptococcus phage Javan520, complete genome	27647-27676	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448786	Streptococcus phage Javan509, complete genome	27472-27501	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448963	Streptococcus phage Javan498, complete genome	23094-23123	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448773	Streptococcus phage Javan485, complete genome	28601-28630	5	0.833
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MK448950	Streptococcus phage Javan464, complete genome	32684-32713	6	0.8
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	MN693570	Marine virus AFVG_25M8, complete genome	48011-48040	6	0.8
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	NZ_CP014852	Bacillus thuringiensis strain HD12 plasmid pHD120161, complete sequence	135700-135729	7	0.767
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	NC_010895	Bacillus thuringiensis serovar tenebrionis plasmid pBMB175, complete sequence	869-898	7	0.767
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	CP020760	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-21, complete sequence	3892-3921	7	0.767
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	NC_005567	Bacillus thuringiensis H1.1 plasmid pGI3, complete sequence	1823-1852	7	0.767
CP031625_1	1.2\|604243\|32\|CP031625\|PILER-CR	604243-604274	32	MK448704	Streptococcus phage Javan213, complete genome	8201-8232	8	0.75
CP031625_2	2.2\|1098195\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098195-1098224	30	NC_013792	Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence	63431-63460	8	0.733
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	NZ_CP031836	Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence	84673-84702	8	0.733
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	NZ_CP020458	Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence	86560-86589	8	0.733
CP031625_2	2.4\|1098327\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098327-1098356	30	NC_021559	Prochlorococcus phage P-SSM3 genomic sequence	77011-77040	8	0.733
CP031625_2	2.3\|1098261\|30\|CP031625\|CRISPRCasFinder,CRT,PILER-CR	1098261-1098290	30	MN694808	Marine virus AFVG_250M14, complete genome	476-505	9	0.7

1. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

2. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

3. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

4. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448829 (Streptococcus phage Javan7, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

5. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

6. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

7. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

8. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

9. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

10. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MH853355 (Streptococcus phage LF1, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

11. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

12. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

13. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

14. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

15. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

16. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

17. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

18. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

19. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

20. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

21. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

22. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

23. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MH853358 (Streptococcus phage LF4, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

24. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

25. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

26. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 0, identity: 1.0

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttaatatgtc	Protospacer
******************************

27. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

28. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

29. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

30. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

31. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

32. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

33. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

34. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

35. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

36. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

37. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

38. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 0, identity: 1.0

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctctatt	Protospacer
******************************

39. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

40. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

41. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

42. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

43. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 0, identity: 1.0

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttcta	Protospacer
******************************

44. spacer 2.4|1098327|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448662 (Streptococcus satellite phage Javan97, complete genome) position: , mismatch: 0, identity: 1.0

aataatcagtttaaaaatccatctggagca	CRISPR spacer
aataatcagtttaaaaatccatctggagca	Protospacer
******************************

45. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448522 (Streptococcus satellite phage Javan519, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

46. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448330 (Streptococcus satellite phage Javan136, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

47. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448328 (Streptococcus satellite phage Javan130, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

48. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448513 (Streptococcus satellite phage Javan479, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

49. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448332 (Streptococcus satellite phage Javan142, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

50. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448331 (Streptococcus satellite phage Javan138, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
*********************************************

51. spacer 1.1|604177|33|CP031625|PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

52. spacer 1.1|604177|33|CP031625|PILER-CR matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

53. spacer 1.1|604177|33|CP031625|PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

54. spacer 1.1|604177|33|CP031625|PILER-CR matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

55. spacer 1.1|604177|33|CP031625|PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

56. spacer 1.1|604177|33|CP031625|PILER-CR matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 1, identity: 0.97

taaataattacatgactagccaatacacccaca	CRISPR spacer
caaataattacatgactagccaatacacccaca	Protospacer
.********************************

57. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

58. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

59. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

60. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

61. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

62. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

63. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

64. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 1, identity: 0.969

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttactctcaaagtaagag	Protospacer
.*******************************

65. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtttagctctatt	Protospacer
*******************.**********

66. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

67. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

68. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

69. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

70. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

71. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

72. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

73. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

74. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 1, identity: 0.967

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gccaaactcaattttttgtctagctctatt	Protospacer
*.****************************

75. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.967

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatttctg	Protospacer
*****************************.

76. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448333 (Streptococcus satellite phage Javan145, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
**************************************.******

77. spacer 3.1|1851273|45|CP031625|CRISPRCasFinder matches to MK448340 (Streptococcus satellite phage Javan156, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
**************************************.******

78. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

79. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

80. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

81. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

82. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

83. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

84. spacer 1.2|604243|32|CP031625|PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

85. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

86. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

87. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

88. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

89. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

90. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

91. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

92. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

93. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttactctcaaagtaagag	Protospacer
.***********.*******************

94. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.938

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagctgctttactctcaaagtaagag	Protospacer
.********** ********************

95. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448755 (Streptococcus phage Javan423, complete genome) position: , mismatch: 2, identity: 0.933

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttatcatgtc	Protospacer
*********************** .*****

96. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to MK448756 (Streptococcus phage Javan425, complete genome) position: , mismatch: 2, identity: 0.933

ggaaagcaggagaaaggacgttaatatgtc	CRISPR spacer
ggaaagcaggagaaaggacgttatcatgtc	Protospacer
*********************** .*****

97. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

98. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

99. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

100. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

101. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to M19348 (Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

102. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaattcaattttttgtttagctctatt	Protospacer
******.************.**********

103. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

104. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 2, identity: 0.933

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gttaagctcaattttttgtctagctctatt	Protospacer
**.**.************************

105. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 2, identity: 0.933

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
agacaaaagaaaaagcattgtcaatctctg	Protospacer
*************************.***.

106. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 3, identity: 0.906

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttttttaccctcaaagtaagag	Protospacer
.***********.*****.*************

107. spacer 2.1|1098129|30|CP031625|CRISPRCasFinder,CRT matches to NC_028666 (Streptococcus phage Str-PAP-1, complete genome) position: , mismatch: 3, identity: 0.9

ggaaagcaggagaaaggacgttaatatgtc-	CRISPR spacer
gcaaagcaggagaaaggacgtt-acatgtca	Protospacer
* ******************** *.*****

108. spacer 1.2|604243|32|CP031625|PILER-CR matches to NZ_CP020429 (Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttagtctcaaaataagaa	Protospacer
.**************** *******.*****.

109. spacer 1.2|604243|32|CP031625|PILER-CR matches to NZ_CP020439 (Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttagtctcaaaataagaa	Protospacer
.**************** *******.*****.

110. spacer 1.2|604243|32|CP031625|PILER-CR matches to NZ_CP018188 (Streptococcus salivarius strain ICDC2 plasmid, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttattctcaaaataagaa	Protospacer
.****************.*******.*****.

111. spacer 1.2|604243|32|CP031625|PILER-CR matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttattctcaaaataagaa	Protospacer
.****************.*******.*****.

112. spacer 1.2|604243|32|CP031625|PILER-CR matches to MN480763 (Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence) position: , mismatch: 4, identity: 0.875

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
cttcatgagcttctttagtctcaaaataagaa	Protospacer
.**************** *******.*****.

113. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 4, identity: 0.867

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttttgtctagctttgca	Protospacer
*************************.*..

114. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 5, identity: 0.844

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
tggaataagctgctttactctcaaagtaagag	Protospacer
*   **.**** ********************

115. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

116. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

117. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448976 (Streptococcus phage Javan528, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

118. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

119. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

120. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

121. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

122. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 5, identity: 0.833

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaatttttcgtctagctttgca	Protospacer
****************.********.*..

123. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 6, identity: 0.8

gtcaaactcaattttttgtctagctctatt	CRISPR spacer
gtcaaactcaattttccgtctagctttgca	Protospacer
***************..********.*..

124. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MN693570 (Marine virus AFVG_25M8, complete genome) position: , mismatch: 6, identity: 0.8

gtcaaactcaattttttgtctagc-tctatt	CRISPR spacer
attaaactcaattttttgactagcatgtaa-	Protospacer
.*.*************** ***** * **

125. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014852 (Bacillus thuringiensis strain HD12 plasmid pHD120161, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
caccagaagcaaaagcattgtcaatttccg	Protospacer
 . **.*** ******************..

126. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_010895 (Bacillus thuringiensis serovar tenebrionis plasmid pBMB175, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttact	Protospacer
*.* *********** ***.******* .

127. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to CP020760 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-21, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttacc	Protospacer
*.* *********** ***.******* .

128. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_005567 (Bacillus thuringiensis H1.1 plasmid pGI3, complete sequence) position: , mismatch: 7, identity: 0.767

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
aaagaaaagaaaaagaattatcaatttacc	Protospacer
*.* *********** ***.******* .

129. spacer 1.2|604243|32|CP031625|PILER-CR matches to MK448704 (Streptococcus phage Javan213, complete genome) position: , mismatch: 8, identity: 0.75

tttcatgagcttctttactctcaaagtaagag	CRISPR spacer
ttgcatgagcttctttgctctcaaatgcgctg	Protospacer
** *************.********   .  *

130. spacer 2.2|1098195|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_013792 (Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence) position: , mismatch: 8, identity: 0.733

---gtcaaactcaattttttgtctagctctatt	CRISPR spacer
ccttttga---taatttcttgtctagctctatt	Protospacer
    *..*   .*****.***************

131. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031836 (Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
taaaaaaagaaaaagcatcgtcaattagac	Protospacer
 .* **************.*******

132. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020458 (Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence) position: , mismatch: 8, identity: 0.733

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
taaaaaaagaaaaagcatcgtcaattagac	Protospacer
 .* **************.*******

133. spacer 2.4|1098327|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to NC_021559 (Prochlorococcus phage P-SSM3 genomic sequence) position: , mismatch: 8, identity: 0.733

aataatcagtttaaaaatccatctggagca	CRISPR spacer
tataagaagtttaaaaatccatctcaaatg	Protospacer
 ****  ***************** .*...

134. spacer 2.3|1098261|30|CP031625|CRISPRCasFinder,CRT,PILER-CR matches to MN694808 (Marine virus AFVG_250M14, complete genome) position: , mismatch: 9, identity: 0.7

agacaaaagaaaaagcattgtcaatttcta	CRISPR spacer
caggaaaagaaaaaggattgtcaataccct	Protospacer
 .. *********** ********* .*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36552 : 48865

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB47913.1\|36552_40278_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.1e-38	26.3
QBB47914.1\|40438_41893_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	32.7
QBB47915.1\|41920_42943_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	2.4e-63	42.1
QBB47916.1\|43110_43665_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.8e-25	35.6
QBB47917.1\|43848_45396_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.4e-45	52.4
QBB47918.1\|45453_46578_-	CHAP domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
QBB47919.1\|46830_48096_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
QBB47920.1\|48373_48865_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

588562 : 651299

Temperate_phage(81.25%)

integrase,transposase,tRNA,capsid,tail,portal,terminase

attL 580553:580571|attR 636366:636384

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
580553:580571	attL	NA	NA	NA	NA
QBB48381.1\|588562_589699_+\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	2.3e-43	31.0
QBB48382.1\|590035_591169_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
QBB48383.1\|591337_591592_+	DUF1912 family protein	NA	NA	NA	NA
QBB48384.1\|591612_592008_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
QBB48385.1\|592030_592264_-	hypothetical protein	NA	NA	NA	NA
QBB48386.1\|592433_592613_+	N-acetyltransferase	NA	NA	NA	NA
QBB48387.1\|592609_593173_+	shikimate kinase	NA	NA	NA	NA
QBB48388.1\|593174_595823_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	2.3e-150	40.4
QBB48389.1\|595976_598385_+	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
QBB48390.1\|598517_599246_+	type I-C CRISPR-associated protein Cas5	NA	NA	NA	NA
QBB48391.1\|599245_601141_+	type I-C CRISPR-associated protein Cas8c/Csd1	NA	NA	NA	NA
QBB48392.1\|601145_601994_+	type I-C CRISPR-associated protein Cas7/Csd2	NA	NA	NA	NA
QBB48393.1\|601995_602670_+	CRISPR-associated protein Cas4	NA	NA	NA	NA
QBB48394.1\|602666_603692_+	type I-C CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
QBB48395.1\|603702_603996_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
QBB48396.1\|604466_605177_+	cytochrome c biogenesis protein CcdA	NA	NA	NA	NA
QBB48397.1\|605189_605813_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
QBB48398.1\|605855_606962_+	peptide-methionine (R)-S-oxide reductase	NA	NA	NA	NA
QBB48399.1\|607072_608227_-\|integrase	site-specific integrase	Q938N9	Temperate_phage	2.8e-206	100.0
QBB48400.1\|608345_608867_-	hypothetical protein	Q938N8	Temperate_phage	2.3e-67	100.0
QBB48401.1\|608877_609258_-	ImmA/IrrE family metallo-endopeptidase	Q938N7	Temperate_phage	5.3e-69	100.0
QBB48402.1\|609271_609631_-	XRE family transcriptional regulator	Q938N6	Temperate_phage	1.1e-60	100.0
QBB48403.1\|610426_610618_+	hypothetical protein	A7J270	Streptococcus_phage	1.2e-24	90.5
QBB48404.1\|610628_611357_+	oxidoreductase	Q938N5	Temperate_phage	6.9e-134	100.0
QBB48405.1\|611535_611736_-	KTSC domain-containing protein	A0A1S5S8T9	Streptococcus_phage	6.3e-21	72.3
QBB48406.1\|611724_611979_+	hypothetical protein	NA	NA	NA	NA
QBB48407.1\|611905_612118_-	hypothetical protein	NA	NA	NA	NA
QBB48408.1\|612224_612482_+	hypothetical protein	NA	NA	NA	NA
QBB48409.1\|612510_612696_+	hypothetical protein	Q938N3	Temperate_phage	1.1e-24	100.0
QBB48410.1\|612789_613047_+	transcriptional regulator	A0A1S5SFN6	Streptococcus_phage	1.2e-11	46.4
QBB48411.1\|613192_613582_+	DnaD domain protein	Q938N2	Temperate_phage	1.1e-58	99.2
QBB48412.1\|613562_613796_+	hypothetical protein	Q938N1	Temperate_phage	5.0e-38	100.0
QBB48413.1\|613792_613933_+	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	7.5e-05	52.3
QBB48414.1\|613943_614198_+	hypothetical protein	Q938N0	Temperate_phage	7.4e-43	100.0
QBB48415.1\|614219_614702_+	hypothetical protein	Q938M9	Temperate_phage	8.2e-51	100.0
QBB48416.1\|614702_615377_+	single-stranded DNA-binding protein	Q938M8	Temperate_phage	2.5e-106	100.0
QBB48417.1\|615369_615789_+	single-stranded DNA-binding protein	Q938M7	Temperate_phage	1.6e-71	100.0
QBB48418.1\|615794_615998_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
QBB48419.1\|615997_616438_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	8.5e-79	97.3
QBB48420.1\|616434_616791_+	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	1.6e-51	85.6
QBB48421.1\|616787_617039_+	hypothetical protein	Q938M4	Temperate_phage	2.6e-40	98.8
QBB48422.1\|617032_617317_+	DUF3310 domain-containing protein	Q938M3	Temperate_phage	5.4e-50	100.0
QBB48423.1\|617313_617583_+	hypothetical protein	Q938M2	Temperate_phage	4.0e-47	100.0
QBB48424.1\|617592_617997_+	hypothetical protein	Q938M1	Temperate_phage	6.0e-71	100.0
QBB48425.1\|618160_618667_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	9.8e-95	100.0
QBB48426.1\|619107_619548_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
QBB48427.1\|619693_619915_+	hypothetical protein	NA	NA	NA	NA
QBB48428.1\|620024_620288_+	hypothetical protein	NA	NA	NA	NA
QBB48429.1\|620262_620448_-	hypothetical protein	NA	NA	NA	NA
QBB48430.1\|620524_621043_+	chromosome partitioning protein ParB	Q938L7	Temperate_phage	1.5e-90	100.0
QBB48431.1\|621021_621699_+	hypothetical protein	Q938L6	Temperate_phage	8.7e-131	100.0
QBB49649.1\|621821_622091_+	hypothetical protein	B5SP24	Lactococcus_phage	2.8e-16	51.1
QBB48432.1\|622151_622529_+	ASCH domain-containing protein	Q938L5	Temperate_phage	1.7e-67	100.0
QBB49650.1\|622579_623053_+	hypothetical protein	Q938L4	Temperate_phage	4.3e-76	99.4
QBB48433.1\|623135_624347_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
QBB48434.1\|624360_625863_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.4e-282	100.0
QBB48435.1\|625867_627346_+\|capsid	capsid protein	Q938L1	Temperate_phage	8.2e-275	100.0
QBB48436.1\|627317_627557_+	hypothetical protein	Q938L0	Temperate_phage	2.8e-36	100.0
QBB48437.1\|627618_627885_+	hypothetical protein	Q938K9	Temperate_phage	1.5e-38	100.0
QBB48438.1\|628010_628625_+	hypothetical protein	Q938K8	Temperate_phage	1.3e-96	100.0
QBB48439.1\|628628_629447_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
QBB48440.1\|629500_629917_+	hypothetical protein	Q938K7	Temperate_phage	1.1e-56	100.0
QBB48441.1\|629906_630239_+\|capsid	minor capsid protein	Q79S86	Temperate_phage	9.6e-59	100.0
QBB48442.1\|630238_630595_+\|capsid	capsid protein	Q79S88	Temperate_phage	4.5e-62	100.0
QBB48443.1\|630591_630990_+\|capsid	capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
QBB48444.1\|630989_631475_+\|tail	phage tail protein	Q938K6	Temperate_phage	1.6e-86	100.0
QBB48445.1\|631513_631948_+	hypothetical protein	Q938K5	Temperate_phage	2.6e-72	100.0
QBB48446.1\|631951_632533_+	hypothetical protein	Q938K4	Temperate_phage	1.3e-106	100.0
QBB48447.1\|632522_635783_+	tape measure domain-containing protein	Q938K3	Temperate_phage	0.0e+00	99.9
QBB48448.1\|635779_636496_+\|tail	phage tail protein	Q938K2	Temperate_phage	2.9e-137	100.0
636366:636384	attR	NA	NA	NA	NA
QBB48449.1\|636492_638637_+	peptidase	Q938K1	Temperate_phage	0.0e+00	100.0
QBB48450.1\|638633_639647_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.2e-184	100.0
QBB48451.1\|639661_641545_+	hyaluronidase	Q938J9	Temperate_phage	2.8e-256	100.0
QBB48452.1\|641556_641988_+	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
QBB48453.1\|641990_642602_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	2.7e-91	100.0
QBB48454.1\|642612_642909_+	hypothetical protein	Q938J6	Temperate_phage	7.5e-47	100.0
QBB48455.1\|642905_643091_+	hypothetical protein	Q938J5	Temperate_phage	1.7e-25	100.0
QBB48456.1\|643201_644404_+	CHAP domain-containing protein	Q938J4	Temperate_phage	3.3e-242	100.0
QBB48457.1\|644543_645068_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
QBB48458.1\|645055_645922_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	3.7e-134	100.0
QBB48459.1\|646225_647005_+	pyrogenic exotoxin SpeK	Q938J1	Temperate_phage	5.4e-145	100.0
QBB48460.1\|647480_648056_+	phospholipase	Q938J0	Temperate_phage	1.7e-111	100.0
QBB48461.1\|648049_648337_+	hypothetical protein	Q938I9	Temperate_phage	2.4e-29	100.0
QBB48462.1\|648401_648584_+	Paratox	A3F673	Streptococcus_phage	2.6e-18	76.7
QBB48463.1\|648828_649569_+	DNA-binding response regulator	Q6XM27	Feldmannia_irregularis_virus	8.0e-05	32.4
QBB48464.1\|649565_651299_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	3.9e-26	33.2

DBSCAN-SWA_3

823236 : 922826

114

Streptococcus_phage(40.3%)

integrase,transposase,tRNA,capsid,tail,portal,terminase,head

attL 843207:843266|attR 889379:889474

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB48621.1\|823236_823461_-\|transposase	transposase	NA	NA	NA	NA
QBB48622.1\|823780_825040_+	extracellular solute-binding protein	NA	NA	NA	NA
QBB48623.1\|825205_826909_+	alpha-glycosidase	NA	NA	NA	NA
QBB48624.1\|826934_829070_+	cyclomaltodextrin glucanotransferase	NA	NA	NA	NA
QBB48625.1\|829144_830452_+	sugar ABC transporter permease	NA	NA	NA	NA
QBB48626.1\|830448_831309_+	sugar ABC transporter permease	NA	NA	NA	NA
QBB48627.1\|831330_832146_+	maltodextrose utilization protein malA	NA	NA	NA	NA
QBB48628.1\|832261_833062_-	LacI family transcriptional regulator	NA	NA	NA	NA
QBB48629.1\|833216_834053_-	sugar ABC transporter permease	NA	NA	NA	NA
QBB48630.1\|834052_835414_-	sugar ABC transporter permease	NA	NA	NA	NA
QBB48631.1\|835687_836935_-	extracellular solute-binding protein	NA	NA	NA	NA
QBB48632.1\|837177_838197_+	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
QBB48633.1\|838312_839806_+	4-alpha-glucanotransferase	NA	NA	NA	NA
QBB48634.1\|839840_842105_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
QBB48635.1\|842361_842982_-	DUF3862 domain-containing protein	NA	NA	NA	NA
843207:843266	attL	NA	NA	NA	NA
QBB48636.1\|843344_844433_-\|integrase	site-specific integrase	Q38159	Streptococcus_phage	3.0e-202	98.6
QBB48637.1\|844682_845492_-	MazF family toxin-antitoxin system	J7KDP1	Streptococcus_phage	3.8e-24	35.8
QBB48638.1\|845504_846248_-	helix-turn-helix domain-containing protein	A0A1S5S8T5	Streptococcus_phage	2.5e-75	62.9
QBB48639.1\|846740_846956_-	hypothetical protein	J7KBX0	Streptococcus_phage	2.5e-28	95.7
QBB48640.1\|847014_847173_+	hypothetical protein	J7KH24	Streptococcus_phage	8.4e-21	90.4
QBB48641.1\|847202_847802_-	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	3.1e-108	100.0
QBB48642.1\|847855_848065_+	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	1.7e-32	100.0
QBB48643.1\|848053_848440_-	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	1.2e-65	100.0
QBB48644.1\|848513_848741_+	XRE family transcriptional regulator	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
QBB48645.1\|848848_849358_-	hypothetical protein	NA	NA	NA	NA
QBB48646.1\|849412_849658_+	hypothetical protein	A0A097PAP6	Streptococcus_pyogenes_phage	1.2e-34	95.1
QBB48647.1\|849616_849826_-	hypothetical protein	NA	NA	NA	NA
QBB48648.1\|849975_850215_-	hypothetical protein	NA	NA	NA	NA
QBB48649.1\|850381_850567_+	XRE family transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
QBB48650.1\|850645_850942_+	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
QBB48651.1\|850938_851076_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
QBB48652.1\|851156_851486_+	hypothetical protein	J7KBZ0	Streptococcus_phage	7.9e-13	41.8
QBB48653.1\|851485_851680_+	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
QBB48654.1\|851676_851961_+	hypothetical protein	NA	NA	NA	NA
QBB48655.1\|851957_852641_+	DNA-binding protein	J7KC09	Streptococcus_phage	9.4e-125	99.1
QBB48656.1\|852676_854080_+	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.3
QBB48657.1\|854084_854567_+	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
QBB48658.1\|854584_856138_+	phage resistance protein	A0A1P8BM51	Lactococcus_phage	5.7e-210	70.6
QBB48659.1\|856406_857276_+	hypothetical protein	A0A1P8BME8	Lactococcus_phage	5.8e-103	65.6
QBB48660.1\|857229_857580_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	9.9e-46	88.5
QBB48661.1\|857563_857920_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
QBB48662.1\|857916_858162_+	hypothetical protein	A0A097PBE9	Streptococcus_pyogenes_phage	2.1e-39	95.1
QBB48663.1\|858161_858398_+	DUF3310 domain-containing protein	A0A097PAQ7	Streptococcus_pyogenes_phage	2.4e-40	100.0
QBB48664.1\|858561_858846_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
QBB48665.1\|858847_859480_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.1e-85	68.6
QBB49654.1\|859484_859964_+	DUF1642 domain-containing protein	A0A141E0J6	Streptococcus_phage	6.5e-24	41.9
QBB48666.1\|860412_860847_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	6.2e-74	97.9
QBB48667.1\|861424_862339_+	hypothetical protein	NA	NA	NA	NA
QBB48668.1\|862357_862819_+	hypothetical protein	NA	NA	NA	NA
QBB48669.1\|862956_863334_-	HicB family protein	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
QBB48670.1\|863385_863571_-	addiction module toxin, HicA family	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
QBB49655.1\|863633_864101_+\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.1e-52	70.8
QBB48671.1\|864078_865386_+\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.0e-184	75.7
QBB48672.1\|865397_866900_+\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
QBB48673.1\|866880_868443_+\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	2.5e-48	44.2
QBB48674.1\|868446_868632_+	hypothetical protein	NA	NA	NA	NA
QBB48675.1\|868701_869016_+	hypothetical protein	M1PLI3	Streptococcus_phage	6.8e-38	72.8
QBB48676.1\|869018_869285_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.9e-25	70.5
QBB48677.1\|869428_869962_+	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	6.8e-14	80.7
QBB48678.1\|869971_870352_+\|head	head decoration protein	A0A0K2CNR0	Brevibacillus_phage	1.8e-05	32.5
QBB48679.1\|870354_871437_+\|capsid	minor capsid protein E	A0A2H4J022	uncultured_Caudovirales_phage	3.4e-105	57.1
QBB48680.1\|871446_871689_+	hypothetical protein	NA	NA	NA	NA
QBB48681.1\|871702_872056_+	hypothetical protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
QBB48682.1\|872052_872361_+	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	7.4e-13	40.2
QBB48683.1\|872341_872707_+	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	5.9e-17	46.3
QBB48684.1\|872703_873093_+\|capsid	phage capsid protein	B5SP36	Lactococcus_phage	4.2e-45	68.2
QBB49656.1\|873147_873771_+\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	3.2e-39	50.5
QBB48685.1\|873824_874178_+	hypothetical protein	Q77RZ7	Lactococcus_phage	5.5e-20	48.6
QBB49657.1\|874252_874549_+	hypothetical protein	A0A0S2MYH1	Enterococcus_phage	1.3e-09	42.2
QBB48686.1\|874563_878199_+\|tail	phage tail protein	C5IUK3	Streptococcus_phage	1.2e-85	41.4
QBB48687.1\|878230_879010_+\|tail	phage tail protein	A3F655	Streptococcus_phage	1.9e-65	54.0
QBB48688.1\|879006_881061_+	hypothetical protein	A3F656	Streptococcus_phage	0.0e+00	84.1
QBB48689.1\|881057_882272_+	hypothetical protein	A3F657	Streptococcus_phage	5.0e-44	49.5
QBB48690.1\|882273_882588_+	hypothetical protein	NA	NA	NA	NA
QBB48691.1\|882598_884494_+	hyaluronidase	Q938J9	Temperate_phage	5.9e-76	52.5
QBB48692.1\|884507_884669_+	hypothetical protein	NA	NA	NA	NA
QBB48693.1\|884671_885289_+	hypothetical protein	A3F662	Streptococcus_phage	9.8e-89	94.6
QBB48694.1\|885299_885596_+	hypothetical protein	Q938J6	Temperate_phage	3.7e-46	98.0
QBB48695.1\|885592_885778_+	hypothetical protein	Q938J5	Temperate_phage	6.6e-25	96.7
QBB48696.1\|885889_887224_+	lysin	Q5MY96	Streptococcus_phage	1.3e-247	93.0
QBB48697.1\|887299_888007_-	exotoxin type C	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
QBB48698.1\|888117_888876_-	DNAse	NA	NA	NA	NA
QBB48699.1\|889115_889304_+	Paratox	A3F673	Streptococcus_phage	2.1e-18	76.3
QBB48700.1\|889894_890509_+	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
889379:889474	attR	NA	NA	NA	NA
QBB48701.1\|890635_891421_-	ABC transporter permease	NA	NA	NA	NA
QBB48702.1\|891430_892129_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
QBB48703.1\|892128_892500_-	GntR family transcriptional regulator	NA	NA	NA	NA
QBB48704.1\|892684_895795_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	5.4e-119	29.7
QBB48705.1\|895874_896888_+	ATP-dependent 6-phosphofructokinase	NA	NA	NA	NA
QBB48706.1\|896950_898453_+	pyruvate kinase	NA	NA	NA	NA
QBB48707.1\|898670_899228_+	signal peptidase I	NA	NA	NA	NA
QBB48708.1\|899403_901218_+	glutamine--fructose-6-phosphate aminotransferase	A7IW18	Paramecium_bursaria_Chlorella_virus	1.2e-97	38.7
QBB48709.1\|901413_901749_+	alkylphosphonate utilization protein	NA	NA	NA	NA
QBB48710.1\|901855_902497_+	amino acid ABC transporter permease	NA	NA	NA	NA
QBB48711.1\|902506_903136_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.8e-28	35.5
QBB48712.1\|903151_903988_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
QBB48713.1\|904357_905131_+	hypothetical protein	NA	NA	NA	NA
QBB48714.1\|905500_906736_-	cation diffusion facilitator family transporter	NA	NA	NA	NA
QBB48715.1\|906855_908178_-	sodium:alanine symporter family protein	NA	NA	NA	NA
QBB48716.1\|908706_911025_+	DNA helicase PcrA	A7KV33	Bacillus_phage	2.7e-131	41.2
QBB48717.1\|911387_911636_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
QBB48718.1\|911672_912284_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
QBB48719.1\|912294_912483_+	DUF2273 domain-containing protein	NA	NA	NA	NA
QBB48720.1\|912495_913035_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
QBB48721.1\|913075_913276_+	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
QBB48722.1\|913283_913775_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
QBB48723.1\|913937_914579_+	GntR family transcriptional regulator	NA	NA	NA	NA
QBB48724.1\|914721_915264_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
QBB48725.1\|915381_916083_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	37.0
QBB48726.1\|916097_918734_+	peptide ABC transporter permease	NA	NA	NA	NA
QBB48727.1\|918825_919422_+	restriction endonuclease subunit S	NA	NA	NA	NA
QBB48728.1\|919432_920389_+	aromatic acid exporter family protein	NA	NA	NA	NA
QBB48729.1\|920485_921826_+	DUF2130 domain-containing protein	NA	NA	NA	NA
QBB48730.1\|921941_922826_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA

DBSCAN-SWA_4

1242886 : 1253490

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB49026.1\|1242886_1244029_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3
QBB49027.1\|1244263_1244704_+	hypothetical protein	NA	NA	NA	NA
QBB49028.1\|1244733_1246002_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
QBB49029.1\|1246089_1247442_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.7
QBB49030.1\|1247663_1248005_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
QBB49031.1\|1248065_1249232_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
QBB49032.1\|1249325_1250012_-	3-dehydroquinase	W6LP76	Streptococcus_phage	7.0e-88	68.9
QBB49033.1\|1250008_1251172_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.5e-143	64.9
QBB49034.1\|1251279_1253490_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.5e-267	68.8

DBSCAN-SWA_5

1530939 : 1536813

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB49279.1\|1530939_1531767_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
QBB49280.1\|1531840_1532197_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
QBB49281.1\|1532495_1533125_+	copper homeostasis protein CutC	NA	NA	NA	NA
QBB49282.1\|1533171_1533564_-	hypothetical protein	NA	NA	NA	NA
QBB49283.1\|1533590_1534454_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
QBB49284.1\|1534458_1534782_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
QBB49285.1\|1535284_1536160_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
QBB49286.1\|1536177_1536813_-	thymidylate kinase	M1PSC7	Streptococcus_phage	2.7e-65	63.4

DBSCAN-SWA_6

1799717 : 1819942

Streptococcus_phage(56.25%)

integrase,holin

attL 1802916:1802936|attR 1817243:1817263

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBB49515.1\|1799717_1800938_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.6e-05	23.8
QBB49686.1\|1800948_1802931_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.3e-62	30.1
1802916:1802936	attL	NA	NA	NA	NA
QBB49687.1\|1803025_1804171_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	3.5e-84	44.9
QBB49516.1\|1804425_1804569_+\|holin	putative holin-like toxin	NA	NA	NA	NA
QBB49517.1\|1805430_1806198_-	helix-turn-helix domain-containing protein	Q76TK4	Streptococcus_pyogenes_phage	3.6e-72	83.1
QBB49518.1\|1806351_1806558_+	XRE family transcriptional regulator	X2KUC2	Streptococcus_phage	2.4e-07	47.0
QBB49519.1\|1806591_1806792_+	XRE family transcriptional regulator	A0A1S5SE31	Streptococcus_phage	3.4e-11	56.7
QBB49520.1\|1806812_1807220_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	1.3e-49	69.4
QBB49521.1\|1807631_1808159_+	hypothetical protein	R9QNB1	Lactococcus_phage	9.7e-21	40.2
QBB49522.1\|1808385_1808580_+	CopG family transcriptional regulator	NA	NA	NA	NA
QBB49523.1\|1808779_1808971_+	CopG family transcriptional regulator	NA	NA	NA	NA
QBB49524.1\|1809111_1809564_+	hypothetical protein	NA	NA	NA	NA
QBB49525.1\|1809665_1809998_+	hypothetical protein	NA	NA	NA	NA
QBB49688.1\|1809997_1810189_+	hypothetical protein	NA	NA	NA	NA
QBB49526.1\|1810200_1810530_+	hypothetical protein	NA	NA	NA	NA
QBB49527.1\|1810532_1810805_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.6e-19	60.0
QBB49528.1\|1810805_1811672_+	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	6.1e-121	73.8
QBB49529.1\|1811683_1813078_+	virulence-associated protein E	A0A1W6JQD6	Staphylococcus_phage	1.3e-48	38.1
QBB49530.1\|1813371_1813626_+	hypothetical protein	NA	NA	NA	NA
QBB49531.1\|1813622_1813796_+	DUF2758 domain-containing protein	A0A1X9I5U0	Streptococcus_phage	8.6e-11	59.6
QBB49532.1\|1813976_1814486_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.9e-29	63.5
QBB49533.1\|1814559_1815048_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
QBB49534.1\|1815272_1815455_+	hypothetical protein	NA	NA	NA	NA
QBB49535.1\|1815451_1815814_+	DUF1492 domain-containing protein	NA	NA	NA	NA
QBB49536.1\|1815788_1816172_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	3.7e-14	41.7
QBB49537.1\|1816336_1816990_+	hypothetical protein	NA	NA	NA	NA
QBB49538.1\|1817386_1819942_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	6.8e-43	22.8
1817243:1817263	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1846352 : 1856340

Streptococcus_phage(75.0%)

integrase

attL 1845926:1845940|attR 1853488:1853502

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1845926:1845940	attL	NA	NA	NA	NA
QBB49573.1\|1846352_1846526_-	DUF2758 domain-containing protein	A0A1X9I5U0	Streptococcus_phage	1.9e-10	59.6
QBB49574.1\|1846812_1848426_-	phage resistance protein	A0A1P8BMF9	Lactococcus_phage	2.4e-147	53.1
QBB49575.1\|1848415_1848937_-	hypothetical protein	NA	NA	NA	NA
QBB49576.1\|1848946_1849315_-	hypothetical protein	A0A1X9I6M4	Streptococcus_phage	2.6e-12	47.1
QBB49689.1\|1849223_1849415_-	hypothetical protein	NA	NA	NA	NA
QBB49577.1\|1849414_1849747_-	hypothetical protein	NA	NA	NA	NA
QBB49578.1\|1849758_1849941_-	hypothetical protein	NA	NA	NA	NA
QBB49579.1\|1850161_1850431_-	phage antirepressor protein	NA	NA	NA	NA
QBB49580.1\|1850460_1851027_-	phage repressor protein	A0A0A7S0G2	Clostridium_phage	5.0e-23	42.9
QBB49581.1\|1851042_1851231_-	XRE family transcriptional regulator	A0A1X9I5U7	Streptococcus_phage	1.7e-12	59.7
QBB49582.1\|1851399_1851843_+	XRE family transcriptional regulator	A0A1X9I723	Streptococcus_phage	1.8e-07	48.6
QBB49583.1\|1852022_1853186_+\|integrase	site-specific integrase	A0A1X9I6A9	Streptococcus_phage	2.8e-161	70.5
QBB49584.1\|1853342_1853954_-	30S ribosomal protein S4	NA	NA	NA	NA
1853488:1853502	attR	NA	NA	NA	NA
QBB49585.1\|1854683_1854956_-	hypothetical protein	NA	NA	NA	NA
QBB49586.1\|1854972_1856340_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.0e-154	63.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP031625

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection