CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP035945	Blautia producta strain PMF1 chromosome, complete genome	8 crisprs	RT,c2c10_CAS-V-U3,PD-DExK,WYL,csa3,cas3,DEDDh,cas10,csm3gr7,csx10gr5,csx19,csx1,DinG,cas6	0	12	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP035945_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_2

1095258-1096477

Orphan

Consensus_repeat	Method
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CRISPRCasFinder
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CRT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	PILER-CR

18 spacers

The CRISPR arrays of CP035945_2

>merge|CP035945|2|1095258-1096477|CRISPRCasFinder,CRT,PILER-CR
ATTTCTATCCACATTACTGCGAAGATGATAACTTTCTGAATCACTGTAAGTAAAAATCACATCACCATTTCAATCCACGTCACCGCAAAGGTGACGACAATCGTGATAGGAGAAGGTATGGATACAGGGGATATTTTAATCCACGTCACCGCGAAGGTGACGACCGGAATCCGTGTGGATGGTGATATCGAAAAAGTATTTCAATCCACGTCACCGCGAAGGTGACGACAAACTACTGATGATTAGTTATACTGACTGTTATATTTCAATCCACGTCACCGCGAAGGTGACGACTTATGGAACACCAGATACATACAGGCCCTCATGGATTTCAATCCACGTCACCGCGAAGGTGACGACCATAATCCGAATTATGAGGATATATTCTCTGTTATTTCAATCCACGTCACCGCGAAGGTGACGACTCATGGGAACTGCCGTGGCGACGGCGGAACAGATATTTCAATCCACGTCACCGCGAAGGTGACGACCTTTGCGTCTGGACGCTGGCAAGCCAAGATAAGATTTCAATCCACGTCACCGCGAAGGTGACGACATGGTTGGGAAAAAATGTGGGTAGGCGATTTTGTAATTTCAATCCACGTCACCGCGAAGGTGACGACAATCTTTTTCCGTAAAATATAAAGGAGTAAGTATATTTCAATCCACGTCACCGCGAAGGTGACGACTTTCGTTCTTTATTTCCTGTAACACAGCATAAGGCATTTCAATCCACGTCACCGCGAAGGTGACGACAAGGTAATCTCAGATATAAAAAAGGATAGCCAGCAATTTCAATCCACGTCACCGCGAAGGTGACGACGTACACATTTTTGTTTTCGCCGCTGTGATGATATATTTCAATCCACGTCACCGCGAAGGTGACGACATGATCGCCACAGCAAAGCACAAAAAACTGATTGATATTTCAATCCACGTCACCGCGAAGGTGACGACGCAATAACGTATTGCTCCGGACGCTGGACGTGCGATTTCAATCCACGTCACCGCGAAGGTGACGACGCCATATCTGCAGGGCTGTACCATCCCAGATGTATTTCAATCCACGTCACCGCGAAGGTGACGACGGGGATATCTCCAGTGATGGTCTCGGACAGATAAATTTCAATCCACGTCACCGCGAAGGTGACGACAATAAAGGGCGTGTCAATATCAGCGGAAGCAGCAATTTCAATCCACGTCACCGCGAAGGTGACGAC

>CP035945|2|2|1095258-1096477|CRISPRCasFinder
ATTTCTATCCACATTACTGCGAAGATGATAAC	TTTCTGAATCACTGTAAGTAAAAATCACATCACC
ATTTCAATCCACGTCACCGCAAAGGTGACGAC	AATCGTGATAGGAGAAGGTATGGATACAGGGGAT
ATTTTAATCCACGTCACCGCGAAGGTGACGAC	CGGAATCCGTGTGGATGGTGATATCGAAAAAGT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AAACTACTGATGATTAGTTATACTGACTGTTAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TTATGGAACACCAGATACATACAGGCCCTCATGG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CATAATCCGAATTATGAGGATATATTCTCTGTT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TCATGGGAACTGCCGTGGCGACGGCGGAACAGAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CTTTGCGTCTGGACGCTGGCAAGCCAAGATAAG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	ATGGTTGGGAAAAAATGTGGGTAGGCGATTTTGTA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AATCTTTTTCCGTAAAATATAAAGGAGTAAGTAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TTTCGTTCTTTATTTCCTGTAACACAGCATAAGGC
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AAGGTAATCTCAGATATAAAAAAGGATAGCCAGCA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GTACACATTTTTGTTTTCGCCGCTGTGATGATAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	ATGATCGCCACAGCAAAGCACAAAAAACTGATTGAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GCAATAACGTATTGCTCCGGACGCTGGACGTGCG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GCCATATCTGCAGGGCTGTACCATCCCAGATGT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GGGGATATCTCCAGTGATGGTCTCGGACAGATAA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AATAAAGGGCGTGTCAATATCAGCGGAAGCAGCA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC

>CP035945|2|1|1095258-1096477|CRT
ATTTCTATCCACATTACTGCGAAGATGATAAC	TTTCTGAATCACTGTAAGTAAAAATCACATCACC
ATTTCAATCCACGTCACCGCAAAGGTGACGAC	AATCGTGATAGGAGAAGGTATGGATACAGGGGAT
ATTTTAATCCACGTCACCGCGAAGGTGACGAC	CGGAATCCGTGTGGATGGTGATATCGAAAAAGT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AAACTACTGATGATTAGTTATACTGACTGTTAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TTATGGAACACCAGATACATACAGGCCCTCATGG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CATAATCCGAATTATGAGGATATATTCTCTGTT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TCATGGGAACTGCCGTGGCGACGGCGGAACAGAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CTTTGCGTCTGGACGCTGGCAAGCCAAGATAAG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	ATGGTTGGGAAAAAATGTGGGTAGGCGATTTTGTA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AATCTTTTTCCGTAAAATATAAAGGAGTAAGTAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TTTCGTTCTTTATTTCCTGTAACACAGCATAAGGC
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AAGGTAATCTCAGATATAAAAAAGGATAGCCAGCA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GTACACATTTTTGTTTTCGCCGCTGTGATGATAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	ATGATCGCCACAGCAAAGCACAAAAAACTGATTGAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GCAATAACGTATTGCTCCGGACGCTGGACGTGCG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GCCATATCTGCAGGGCTGTACCATCCCAGATGT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GGGGATATCTCCAGTGATGGTCTCGGACAGATAA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AATAAAGGGCGTGTCAATATCAGCGGAAGCAGCA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC

>CP035945|2|1|1095324-1096477|PILER-CR
ATTTCAATCCACGTCACCGCAAAGGTGACGAC	AATCGTGATAGGAGAAGGTATGGATACAGGGGAT
ATTTTAATCCACGTCACCGCGAAGGTGACGAC	CGGAATCCGTGTGGATGGTGATATCGAAAAAGT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AAACTACTGATGATTAGTTATACTGACTGTTAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TTATGGAACACCAGATACATACAGGCCCTCATGG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CATAATCCGAATTATGAGGATATATTCTCTGTT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TCATGGGAACTGCCGTGGCGACGGCGGAACAGAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	CTTTGCGTCTGGACGCTGGCAAGCCAAGATAAG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	ATGGTTGGGAAAAAATGTGGGTAGGCGATTTTGTA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AATCTTTTTCCGTAAAATATAAAGGAGTAAGTAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	TTTCGTTCTTTATTTCCTGTAACACAGCATAAGGC
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AAGGTAATCTCAGATATAAAAAAGGATAGCCAGCA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GTACACATTTTTGTTTTCGCCGCTGTGATGATAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	ATGATCGCCACAGCAAAGCACAAAAAACTGATTGAT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GCAATAACGTATTGCTCCGGACGCTGGACGTGCG
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GCCATATCTGCAGGGCTGTACCATCCCAGATGT
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	GGGGATATCTCCAGTGATGGTCTCGGACAGATAA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC	AATAAAGGGCGTGTCAATATCAGCGGAAGCAGCA
ATTTCAATCCACGTCACCGCGAAGGTGACGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE95506.1\|1104573_1105557_-\|1,5-anhydro-D-fructose-reductase	unknown	unknown	gnl\|CDD\|223745
CP035945.1\|QBE95497.1\|1092002_1093304_-\|GMP-synthase-[glutamine-hydrolyzing]	unknown	unknown	gnl\|CDD\|234614
CP035945.1\|QBE95498.1\|1093377_1094712_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240542
CP035945.1\|QBE95507.1\|1105866_1106697_-\|Epoxyqueuosine-reductase	unknown	unknown	gnl\|CDD\|224516
CP035945.1\|QBE95508.1\|1106706_1108032_-\|Inner-membrane-protein-YihN	unknown	unknown	gnl\|CDD\|349949
CP035945.1\|QBE95503.1\|1101521_1102046_-\|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl\|CDD\|394878
CP035945.1\|QBE95493.1\|1086560_1087919_-\|Xylosidase/arabinosidase	unknown	unknown	gnl\|CDD\|350132
CP035945.1\|QBE95500.1\|1096725_1098081_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377672
CP035945.1\|QBE95502.1\|1100179_1101448_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225212
CP035945.1\|QBE95490.1\|1080402_1081470_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350147
CP035945.1\|QBE95509.1\|1108135_1108990_-\|Multidrug-efflux-transporter-1-regulator	unknown	unknown	gnl\|CDD\|133382
CP035945.1\|QBE95494.1\|1088277_1089822_-\|GMP-synthase-[glutamine-hydrolyzing]	unknown	unknown	gnl\|CDD\|234614
CP035945.1\|QBE95499.1\|1094796_1095054_-\|Stage-III-sporulation-protein-D	unknown	unknown	gnl\|CDD\|378813
CP035945.1\|QBE95504.1\|1102063_1103419_-\|Multidrug-export-protein-MepA	unknown	unknown	gnl\|CDD\|240543
CP035945.1\|QBE95496.1\|1091172_1091850_-\|Pentapeptide-repeat-protein-MfpA	unknown	unknown	gnl\|CDD\|224276
CP035945.1\|QBE95501.1\|1098184_1100071_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377943
CP035945.1\|QBE95495.1\|1089987_1090890_-\|Ferrous-iron-efflux-pump-FieF	unknown	unknown	gnl\|CDD\|223131
CP035945.1\|QBE95492.1\|1084233_1086510_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379971
CP035945.1\|QBE95491.1\|1083121_1084177_+\|HTH-type-transcriptional-activator-RhaR	unknown	unknown	gnl\|CDD\|197666
CP035945.1\|QBE95505.1\|1103415_1104546_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|378416

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE95506.1\|1104573_1105557_-\|1,5-anhydro-D-fructose-reductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	9.10033e-51
CP035945.1\|QBE95497.1\|1092002_1093304_-\|GMP-synthase-[glutamine-hydrolyzing]	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP035945.1\|QBE95498.1\|1093377_1094712_-\|hypothetical-protein	gnl\|CDD\|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	8.2291e-88
CP035945.1\|QBE95507.1\|1105866_1106697_-\|Epoxyqueuosine-reductase	gnl\|CDD\|224516	COG1600, COG1600, Uncharacterized Fe-S protein [Energy production and conversion].	1.66503e-16
CP035945.1\|QBE95508.1\|1106706_1108032_-\|Inner-membrane-protein-YihN	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.02443e-25
CP035945.1\|QBE95503.1\|1101521_1102046_-\|O-acetyl-ADP-ribose-deacetylase	gnl\|CDD\|394878	cd02908, Macro_OAADPr_deacetylase, macrodomain, O-acetyl-ADP-ribose (OAADPr) family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. This family includes eukaryotic macrodomain proteins such as human MacroD1 and MacroD2, and bacterial proteins such as Escherichia coli YmdB; these have been shown to be O-acetyl-ADP-ribose (OAADPr) deacetylases that efficiently catalyze the hydrolysis of OAADPr to produce ADP-ribose and free acetate. OAADPr is a sirtuin reaction product generated from the NAD+-dependent protein deacetylation reactions and has been implicated as a signaling molecule. By acting on mono-ADP-ribosylated substrates, OAADPr deacteylases may reverse cellular ADP-ribosylation.	5.66161e-90
CP035945.1\|QBE95493.1\|1086560_1087919_-\|Xylosidase/arabinosidase	gnl\|CDD\|350132	cd18620, GH43_XylA-like, Glycosyl hydrolase family 43-like protein such as Clostridium stercorarium alpha-L-arabinofuranosidase XylA. This glycosyl hydrolase family 43 (GH43) subgroup belongs to the GH43_AXH-like subgroup which includes enzymes that have been characterized with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), alpha-1,2-L-arabinofuranosidase 43A (arabinan-specific; EC 3.2.1.-), endo-alpha-L-arabinanase as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. The GH43_XylA-like subgroup includes Clostridium stercorarium alpha-L-arabinofuranosidase XylA, and enzymes that have been annotated as having beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), endo-alpha-L-arabinanase (EC 3.2.1.-) as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. AXHs specifically hydrolyze the glycosidic bond between arabinofuranosyl substituents and xylopyranosyl backbone residues of arabinoxylan.	7.53887e-129
CP035945.1\|QBE95500.1\|1096725_1098081_+\|hypothetical-protein	gnl\|CDD\|377672	pfam06541, ABC_trans_CmpB, Putative ABC-transporter type IV. CmpB is a family of membrane proteins that are likely to be part of a two-component type IV ABC-transporter system. Families can transport multiple drugs including ethidium and fluoroquinolones. UniProtKB:Q83XH0 is a member of TCDB family 3.A.1.121.4.	1.97272e-48
CP035945.1\|QBE95502.1\|1100179_1101448_-\|hypothetical-protein	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	9.63297e-70
CP035945.1\|QBE95490.1\|1080402_1081470_-\|hypothetical-protein	gnl\|CDD\|350147	cd18826, GH43_CtGH43-like, Glycosyl hydrolase family 43 protein similar to Clostridium thermocellum exo-beta-1,3-galactanase CtGH43 and Ruminococcus champanellensis arabinanase Ara43A. This uncharacterized glycosyl hydrolase family 43 (GH43) subgroup belongs to a subgroup which includes characterized enzymes with exo-beta-1,3-galactanase (EC 3.2.1.145, also known as galactan 1,3-beta-galactosidase) activity such as Clostridium thermocellum (Ct1,3Gal43A or CtGH43) and Phanerochaete chrysosporium 1,3Gal43A (Pc1, 3Gal43A), and arabinanase (EC 3.2.1.99) activity such as Ruminococcus champanellensis Ara43A. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	5.8935e-153
CP035945.1\|QBE95509.1\|1108135_1108990_-\|Multidrug-efflux-transporter-1-regulator	gnl\|CDD\|133382	cd01107, HTH_BmrR, Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BmrR and YdfL of Bacillus subtilis, and related proteins; N-terminal domain. Bmr is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. BmrR is comprised of two distinct domains that harbor a regulatory (effector-binding) site and an active (DNA-binding) site. The conserved N-terminal domain contains a winged HTH motif that mediates DNA binding, while the C-terminal domain binds coactivating, toxic compounds. BmrR shares the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.27765e-29
CP035945.1\|QBE95494.1\|1088277_1089822_-\|GMP-synthase-[glutamine-hydrolyzing]	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP035945.1\|QBE95499.1\|1094796_1095054_-\|Stage-III-sporulation-protein-D	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	3.04704e-39
CP035945.1\|QBE95504.1\|1102063_1103419_-\|Multidrug-export-protein-MepA	gnl\|CDD\|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	8.55182e-140
CP035945.1\|QBE95496.1\|1091172_1091850_-\|Pentapeptide-repeat-protein-MfpA	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.52835e-15
CP035945.1\|QBE95501.1\|1098184_1100071_-\|hypothetical-protein	gnl\|CDD\|377943	pfam07929, PRiA4_ORF3, Plasmid pRiA4b ORF-3-like protein. Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.	2.56208e-58
CP035945.1\|QBE95495.1\|1089987_1090890_-\|Ferrous-iron-efflux-pump-FieF	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	3.56133e-83
CP035945.1\|QBE95492.1\|1084233_1086510_-\|hypothetical-protein	gnl\|CDD\|379971	pfam17389, Bac_rhamnosid6H, Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.	7.17117e-59
CP035945.1\|QBE95491.1\|1083121_1084177_+\|HTH-type-transcriptional-activator-RhaR	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.23808e-24
CP035945.1\|QBE95505.1\|1103415_1104546_-\|6-phosphogluconolactonase	gnl\|CDD\|378416	pfam10282, Lactonase, Lactonase, 7-bladed beta-propeller. This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyze 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.	2.9981e-84

>CP035945.1|QBE95499.1|1094796_1095054_-|Stage-III-sporulation-protein-D
MKSYIEERAISIANYIIENNATVRQTAREFKVSKSTVHKDVTERLLQLNPSLAKCARRVLDVNKQERHIRGGMATREKYLHKVQK
>CP035945.1|QBE95498.1|1093377_1094712_-|hypothetical-protein
MNRFFSNADLRKLIIPLIIDQFLQAFVGLADSIMVASVGEAAVSGVSLIDTVMVLIINIFTALATGGAVIAGQFIGKKKTENACLATNQLLSFTLKASCIIMVLGYLGKNLIINGIFGKIEADVMYNCNVYLLIVFASVPMIALYNAGASIFRAMGNSTIAMKTSLLMNAINLGGNALLIYGFHRGVEGVAIPTLVSRGVACVVMLCLINNQSRVLHIHHPFSFKTDWMLLKKILYIGIPNGLENSMFQLGKILVLSIVTGFGTASIAANAVSNNVATFAVLPGMSIGFALLTVGAQCVGANDFEQVHYYTKKLMKVAYISLIGINILLMLVMPFIIKAYGLSAEASGYAYKILIYHSICVVTIWPLSFSLPNTLRAAADVRFTMLLAIISMWIFRIGFSVLLGVKLHWGVFGVWVAMTIDWLFRAVCFTVRYARGKWQHQSLV
>CP035945.1|QBE95497.1|1092002_1093304_-|GMP-synthase-[glutamine-hydrolyzing]
MKQDMIVILDLGSTENTVLAREIRAMGVYSEIYPHDITKEELEKLPNVKGIIINGGPNHMVDGVRIDVRQEVYEAGSPVMAIDHEPAACSEKYQDLSEEQRAEILKKFVFDTCKAETNWNMKNFVADQIEIVREQVGDKKVLLALSGGVDSSVVAALLIKAIGKQLTCVHVNHGLMRKGESESVVEVFKDQMDANLVYVDASERFLTKLAGVDDPEQKRKIIGAEFIRVFEEEARKLEGIEFLGQGTIYPDIVESGTKTAKMVKSHHNVGGLPEDLQFKLVEPLKQLFKDEVRACGIELGLPEEMVYRQPFPGPGLGVRCLGAITRERLEAVRESDAILREEFKNAGLDKKVWQYFTVVPDFKSVGVRDNARCFEYPVIIRAVNTVDAMTATIEEVDWKILLKITDRIMKEVKNVNRVCYDMSPKPNATIEWE
>CP035945.1|QBE95496.1|1091172_1091850_-|Pentapeptide-repeat-protein-MfpA
MNSKMFQEPKAPVKLPVTENVSSVLEAAKVSEEEITGCCFKGVFITKFDGKLLRFKKMAFENCKFISCFFDEASFTDVRFKNCDFSNTSLTDVYFKRCSFQSCKAVGADFYGSIMRHVTFLECNLSDMNLDASRMSYVRIKDTNLEESSLSKCGLDNLDLHQVKFAGASFFKTALKGVDMSDCDMDRIIISDGKEELRGAVLNMSQAIVCAKRMGIVIKELETEN
>CP035945.1|QBE95495.1|1089987_1090890_-|Ferrous-iron-efflux-pump-FieF
MEQVKKEFVSDEKAKKIALHVSGVSVAGNVLLSLFKLLAGIIGHSGAMISDAVHSASDVFGTIIAVLGVSISKRKSDADHQYGHDRLECVAAIVLAVILLATGLGIGISGLEKIIKGNSGDAAIPGVIALVAAVVSIVFKEWMYWYTRAAAKKINSGALMAEAWHHRSDALSSIGAFAGILGARLGYPILDPIASVIICLFIGKAAYDIFKDAVDKMVDKSCDDETLEQMRGIISKQTGVLSIDMLHTRLFGAKMYVDIEISADRTLSLEEGHEIAQKVHDAIEKEFPLVKHCMVHVNPV
>CP035945.1|QBE95494.1|1088277_1089822_-|GMP-synthase-[glutamine-hydrolyzing]
MKRETVIVLDFGGQYNQLIARRVRECNVYCEIYSYKTDIEKIKEIQPKGIIFTGGPNSVYLEDSPTYTKEIFELGIPVLGICYGAQLMMHLLGGQVGTAPVREYGKIEVTVEQSCKMFENVSEKTICWMSHNDYIAKEAPGFDIIAHTSDCPVAAVQNTEKNLYAVQFHPEVLHTQEGKKMLSNFVYNVCECSGDWKMDSFVEESIKAIREKVGDGKVLCALSGGVDSSVAAVMLSKAVGNQLTCVFVDHGLLRKNEGDEVEAVFGPEGPYNLNFIRVNAQERFYERLKGAEEPEDKRKIIGEEFIRVFEEEAKKIGTVDFLVQGTIYPDVVESGVGGESTVIKSHHNVGGLPDYVDFKEIIEPLRDLFKDEVRRAGLELGIPDYLVFRQPFPGPGLGIRIIGEVTAEKVEMVQEADAIWREEIANAGLDKEIGQYFAALTNMRSVGVMGDERTYDYAVALRAVTTTDFMTAESAEIPWDVIGKATSRIVNEVKHINRVMYDCTGKPPATIEFE
>CP035945.1|QBE95493.1|1086560_1087919_-|Xylosidase/arabinosidase
MKMRNSFNNTHNPVLPLEYHVPDSEAHVMSDGILYIYGSYDTKEDVYCSEEYHVVSTADMENWEIHETALRGEEIPWFGNPDAPKYPGIDWTHPTPFIQKMIQRDIERGVDMKAMFEAEKNKPKPPLLFAPDCIEKDGKYYLYFCMSDDSEGVAVSDSPIGPFENPTQLPCGGIDPAVFIDEDGQAYYYWGQLFSHGVKLNEDMISFCPEDIVDNLVTEEEHFFHEGSSMRKIGDTYYYVYADMERGKPTALGYSTSTSPMGPFVYRGIIIDNDGCDPESWNNHGSIECVNGQWYVFYHRCSRGVQQHRRLCVEPITILEDGSIPEVKMTSQGPGKPFGIGEHIMGYQACGVTGKCFMGLDGQGSEWLTNIESGDTAVFRYIESDEGFRGIVIEGAGEGTIHIFLNDQIAVTVVMKDGTAKADWNDPMCGNYEVKLKFEKTSNLSVRTLTFV
>CP035945.1|QBE95492.1|1084233_1086510_-|hypothetical-protein
MNKLWKQWITNHTKKPFYARKEFDVKNKVEKAVVKICGLGQFELHLNGKKVGDHELDPAWTEYRKMVQYVTFDVTDVLRQGRNVIGAEVGNGWFHLDDSEGYSFKFPEFMPPNPNPYHAYGEHLVLGLVLEIMYSNGTRELIETDTTWKTISHEVISSNVYGSELIDQNLCQKNWDSCEFDDSSWNQAKAASNEDIPEGKLLEQTMPPVKVIHSYEAKHCGKPSGSTETEIYDLSQNCSFMLSFEVKGRKGDIVKFYPAEKLNSQGDVDQFAKGWTMVNNCITFIVGTDQEWEKYRQKFSYSAGRYIRIECSNPGIEIRNVYGHAISSAWEEAGSFYSDDRRYKQIYDLVEKAVEANMVGVHTDCPTIERFAWQEPNHLMAPAIFYMKNGKELWRKFLMDMRISQHTTEDIFYDFDGNVIYPGEGLMPSQCPCYIPNVIPVPGMGSFYDIIAWGSTCILGTRWHYIFYGDQSIIEENYEAGKRYFSHLMTMVNEDGFINHGLGDWGNPENELGRENIETAFLYADAKTLSWFASILGNKEDELKYREEADLIEENYNKHLLVRNENGKWCYRNYEHQDRIVMTQACEALPLYWGMVPEECKEDVVEVFRQTLCEKKAFVTGEVGLPYVIQTAAEYGMNDLIAQFITREQHPSYYAFVLDGLTTLGEYWEENPRSQCHDMMGHITEWFYNGIAGIQPLEPGFKKVLIKPYLPSSMNEVKATYHSACGKIEVELHRTSSEVAVQVCTDDGILVTIDKSNL
>CP035945.1|QBE95491.1|1083121_1084177_+|HTH-type-transcriptional-activator-RhaR
MDSNNFFAIQMSTELREFEQILKKLYQRNPDKYLDLPHDMQYTHDLLKHAITKLNDNDAYLSKLLLSDLQEQNFFQKDLDVEIYQHLRYLPAQTHSHSFFEIVYVLQGECINYANNHALAMEEGDICILAPETSHALSVFTDNCIVFNIEIRTSTFETAFWDTLSDNDILANFFARTLYHSPSHPYLYFKTGTDYELQSYLGFVYDEYHDKRQFKKRMMNAIITAFFIVLLRNHGSDVILPNDGTEVTDPNTLFILKYMQEHFTTITLKELSDFFSYSERQMQRIIKSSTGKSFSENIQQLKMKKAARLLENSDLSISKIAEELGYVDPGNFRNIFKKYYGMTLSEYRSKL
>CP035945.1|QBE95490.1|1080402_1081470_-|hypothetical-protein
MKNTIKPGKTWLDTEGKRIQAHGGSVICVDQKFYWYGENKEKTMGADELWHWGVRCYSSDDLCEWKDEGVIIPPDLDDPTFPLHPNSMMDRPHIIYNEKTKKYVAWLKIMNDPSGFAVLTADHILGPYEMVDPHVNPFGQLVGDFDLYVDEKTGKGYVISEKPHTAVYCADLNEEYTAAQGTYSEHFPHEAPPISREAPAHFVRNGKHYLITSGTTGYFSNPSEAAVADELHGPYKVLGNPHPSDTSKTSFNSQISSVFKHPYKDDLYIAIADRWRPEIPETAGEDYWNGKYSDRIQEKFKRIFDPEIEFVFTEEDAKDMRINSSMSDYVWLPLQFEGDKVIIEWLDEWSVEDYK
>CP035945.1|QBE95500.1|1096725_1098081_+|hypothetical-protein
MNYTLYQLLWFFLLYSFIGWAIGTSVAAVREHRFIDVGFLFGPYCPAYGFGAVAFAVFLPELKNHLFFLFLGGVILSSAITFSTGFVLEKIFHRKWWDYSRKRFQFGGYVNLPYTVVWGLSAVACISLVNPALKELLTLIPSNLGTILLIILYTILCLDLAGTVTAIKAVHSRLRKLSIIEDVSENLQKAADVMGEGLTGWMQKHIAKAYPSLEAKELLAARQEKERLLEAAKERAGVFAVGCSFYKLVCLFFLGAFLGDITETIFCLATTGKLMSRSSVVYGPFSIVWGLGCVLLTAILYQYRNRSDSYIFIFGTILGGAYEYICSVFTELVFGTVFWDYSGIPFNLGGRINLLYCFFWGIAAVIWLKYLYPRLSSLIEKIPQKAGIPITWLMILFMVFNIIMSGLALNRYTERHSHTSAPENAVTRFLDKHFTDERMEHIYPNAILVDD
>CP035945.1|QBE95501.1|1098184_1100071_-|hypothetical-protein
MKAYQMKIAIKNSHPPIWRRFIVPAGLSFSQLSIVLNGVMGWCGYHLFKFEFYHLRLNIKEKYEDFIGLGEEEQLEASETIIDPFMEQEDWFSYIYDFGDYWEHKVTIEKVIEDYGFSYPVVLKYKGETPFEDCGGIYRYYDLQEILKDPSHPEHENMKAWTEGHFTRDYDLNEVNESLKRMALEKKKSKPMLQNEIYEEIMEKGGGFKTIQGAKESEVDRKNGTLMSERLSEMEDMLKDYTAKYMELKEALDSNIMGATLRDILEEYRKDDLIEICKLHGLSGFRKLLKKDLIDFVYQNLLSKEVMCRCLMYMNDMEMELMDKENTGVDECEEVLGLIECGYAGATYLGEVYVPEDVKAAYNKNCDEEWKKERRRVQGILCHINACVELYGICPLERVISVYKENTGNIISETELREFCYQIPGFLKIFEIVGSELVQETLLEEDRMQQLKKRQGIKPYYNPTKEEIQTLGNYFYVPFDRYMDALADFFVEFMEEEEEDARELCRNIQRIIRCGGQMQDVIDYLQREIVIMDGEDFYQFAEIFMRLWNHTRMHINRGYMPAEMDSPISKKRVQEAAAKLGFRAVDDMPGDKADIIDFQEERRKKVYPNDPCPCGSGKKYKHCCGKKK
>CP035945.1|QBE95502.1|1100179_1101448_-|hypothetical-protein
MKKWKNLIAGLIVLALLMTGCSSVGQTAGNGPEAGSEAAAGNEQGTGQQSAGNGPEAVSETAAGNEQGTGQQSAEDRQTADGEQAVKNGEKTDGRLNVHYLDVGQGNAVLLESQGHYMLIDGGNRKASSFVVSYLKRQNVEALDYILISHFDEDHLAGTIGALYQFPAGKVITADYETDSSIYKSYQQAMDKQGYEETHPSQGDVFSLGSASVRVISPVSYGHQDENEDSVGVIVENGENRFFFGGDMGKTGEKEAMESGVDIAADVFLLNHHGSYLSSGFLERVSPSYAVISCGDGNSYGHPRQDTMGLLEEAGIPVFRTDKQGTVILHSDGKTISWEQEPCNDYTPGTRTASGDKEEPYVEENNSDAENCDYVLNTHTKKIHLPSCSSLKGMKEENKAYYKGSKDELTDNGYEACGNCKP
>CP035945.1|QBE95503.1|1101521_1102046_-|O-acetyl-ADP-ribose-deacetylase
MGRFKIEMGDITTYHVDAIANAANCSLLGGGGVDGAIHRAAGPGLLEECRGLGGCETGQAKITKGYQLPAKYVIHTPGPIWSGGAFGEPELLKNCYENCIRLAHEYGCRTLAFPSISTGIYGYPLEQASEIAVNAIREGLEKYPDIEKILMICFSEKVQKAYQKAYQKMYEKVQ
>CP035945.1|QBE95504.1|1102063_1103419_-|Multidrug-export-protein-MepA
MKKSYEIDMCNGPLWGKLLLFSVPLILSGILQLLFNAADIVVVGRFSGNHALAAVGSTSSLIQLFVNVFIGCSIGTNVLVGRFCGAKDAKNVSETVHTSILFSIVCGCILIFLGVAFAGPMLEWMATPPEVLGQAVLYMRIFFVGMPAMMLYNFGAAVLRATGDTQRPLYYLLLAGIINVVLNLFFVIVCGLGVAGVALATIISQAVSALLILRCLMRTEGMCRLELRKLKIHKDKLKHIVRIGLPAGMQSAIFSISNVLIQSSVNSFGAIAMAGNTAASNLEGFVYTSMNAVYQATLSFTSQNVGAGNQKRISQILWRCLVLVTVIGGTFGCLMVFFSPHLLGIYSSDAEVIAYGIQRLKIICLPYFLCGIMEVLVGSLRGMGYSVLPMLVSLTGACGLRIIWIFTIFMWQHSLFVLYLSYPITWAITAAAHLICWCKLRQMMKKRQLAG
>CP035945.1|QBE95505.1|1103415_1104546_-|6-phosphogluconolactonase
MSEKKQEFLIGTYTESVLFGDGSRFIGNGEGIYLAEIDMVSGKMSLKQTIEGIKNPSYVCADKAGKRIYAVSELEDYEGLESGAVSVYETGEDGSVMLLDRKPSMGTDPCHLYLDEAEEILYISNYGSGSVCAYRIGKDGCFLEPAMVIRHHGRSIDETRQEGPHVHSVHPCRFAEGVLVCDLGLDKISRCAVREKDGRWTFTEEESWMTEPGYGPRMLVHHPVLPMFYVVQEMGNRVLVYDCQNGVPQAVQDVSTLTEEDGGISNTAAEIRIDHAGNKLYVSNRGADNISVYDLDREGRLVFADSISSGGKTPRCFAAAEDRESKSTYLVIANQDSNELISVKYTGAGTAEIKDRMHLGSPVCVWALSVLEGRER
>CP035945.1|QBE95506.1|1104573_1105557_-|1,5-anhydro-D-fructose-reductase
MFRWGIMGGGFISSQFARGLEEVADMQVEVLASKSGRNDYGIQAKKYCRSYEELVSDENVDAVYVGTIHPQHLACVKACLEAKKPVLCEKPVTMNARELEELLCLARENHTFFMEAMWTRFIPVMRELRKEIQEGVYGKVHNMHFTFGGPAKPETRRLFEAELGGGALLDVGVYGVSVAQYLLGETPEVIHAWSEKNEETVDLNTCIQMTYPCGCLADMVFSINRKVDNRAVIITDKAELEIPYFWRPNTVYLFEPNEDFRTDMLKEKRVVEVAGNGYHYEALEVQKMLKEGQTESPVMPWEESLQIMRELDDIRRMCGIRYPQDIE
>CP035945.1|QBE95507.1|1105866_1106697_-|Epoxyqueuosine-reductase
MPEERRMDMNSRAMTELIVKKAIAFGAASAGIANIRDLKTAPAFVMMPQRPHIDRVGAVENTTGLPEGVVDWKDEMHSMLVIAYEHPEEKPYLDCWLDGKNPPGNLELIKINKKLKTFIESEMPGVTAMPLNYYVEKGGVWLKDSAAVAGLGILGKNNLLITKEFGPRVRLRAMFLSADLPSTGPIDWDPCAGCDMPCRKSCPQNAFGTIAYDPEQYGGLAKLPGRDGSYSLLTCDRQMAEDEDNEIKTPTEVPDYGTAGSIIKYCRECELNCRIR
>CP035945.1|QBE95508.1|1106706_1108032_-|Inner-membrane-protein-YihN
MDAQVLYGPEKGGLFMDAANLTPRQRRLKQIWGMLALCICGAAVYELPYLSWSYYDAAVEFYGVSNAQMGYLMTMYGLACVISYLPAGWVADKFQARHLIATALVSTGFFGLILTFRPPYAVLMICYVSYGFTTTIPLWSAMMKATRELGDSSEMGRLYGFLEGGRGFVPVLYGAVIIPIFSYLGEGAGGFRAILIYFVVLDFICAFFALGAIRKLRPDEEDTQEIQTKHKHSFGEYLDMMKNKNLWLLTLLMFCCFMIYESYSYITPYLTNFFGVSESLGAMISLIKSYGLAVFGGIAAGFAADRIHSNPKVIGIGFSLMVIGIATFFVVPAEPKLLGLAAVTILVISLGLFMVRALYFAVIDEIKIPLKYTGMAVGFASVIGCLPQIFIYSITGNLLDAFPGIRGYRYMFAYEFAAALAGAVLAFILYRNIKKENSKNT
>CP035945.1|QBE95509.1|1108135_1108990_-|Multidrug-efflux-transporter-1-regulator
MLENISNNDREVNYLEKRYTIGEVSHITGVSKDTLRYYDRIGVFKPEYVNPDNQYRYYTYSQFWYLDIITCCRRLQIPLERVKAVLDLHDNKKIVEMLQEQRQEALRQREYYARVVDDIDWYTEQNKRLSRMGKDKEIRVKRLQERRVIYGSNKEDEAAYHIKLQEACRDEISHMESIKRNYGYVLNGSKIRENVFHQMGEYIDIRVDEYRFASRENILTIPEGEYACFTTEVRGNFADFGILADWLDERGYSPDFVIADEAGLQLFAYNQYFYPCEIKVLLSS

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Crispr_ID: CP035945_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_3

1323316-1323420

Unclear

Consensus_repeat	Method
TCCCACTTGGCTCGTTGCACCCATTATAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035945_3

>merge|CP035945|3|1323316-1323420|CRISPRCasFinder
TCCCACTTGGCTCGTTGCACCCATTATATTGTGAACTACGTTCCCAATCTTTTGCAGTCGCCAAATGTGAGCTAGCTCCCACTTGGCTCGTTGCGCCCATTATAT

>CP035945|3|3|1323316-1323420|CRISPRCasFinder
TCCCACTTGGCTCGTTGCACCCATTATAT	TGTGAACTACGTTCCCAATCTTTTGCAGTCGCCAAATGTGAGCTAGC
TCCCACTTGGCTCGTTGCGCCCATTATAT

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE95709.1\|1319845_1320745_+\|Formamidase	unknown	unknown	gnl\|CDD\|225279
CP035945.1\|QBE95705.1\|1315605_1316289_-\|Bacitracin-export-ATP-binding-protein-BceA	unknown	unknown	gnl\|CDD\|224059
CP035945.1\|QBE95707.1\|1317269_1317941_-\|Transcriptional-regulatory-protein-YycF	unknown	unknown	gnl\|CDD\|223816
CP035945.1\|QBE95718.1\|1330242_1331010_+\|Thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
CP035945.1\|QBE95712.1\|1323565_1324606_+\|Low-specificity-L-threonine-aldolase	unknown	unknown	gnl\|CDD\|224919
CP035945.1\|QBE95714.1\|1325721_1327719_+\|Alpha-xylosidase-BoGH31A	unknown	unknown	gnl\|CDD\|224418
CP035945.1\|QBE95703.1\|1311114_1312842_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227708
CP035945.1\|QBE95716.1\|1329362_1329560_+\|Sulfur-carrier-protein-ThiS	unknown	unknown	gnl\|CDD\|340451
CP035945.1\|QBE95721.1\|1332802_1333798_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366534
CP035945.1\|QBE95720.1\|1332207_1332792_+\|Thiazole-tautomerase	unknown	unknown	gnl\|CDD\|238317
CP035945.1\|QBE95711.1\|1322124_1323276_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133404
CP035945.1\|QBE95708.1\|1318370_1319819_+\|Malate-2H(+)/Na(+)-lactate-antiporter	unknown	unknown	gnl\|CDD\|188097
CP035945.1\|QBE95719.1\|1331024_1332185_+\|2-iminoacetate-synthase	unknown	unknown	gnl\|CDD\|236425
CP035945.1\|QBE95702.1\|1309279_1310581_-\|Zinc-binding-GTPase-YeiR	unknown	unknown	gnl\|CDD\|349766
CP035945.1\|QBE95706.1\|1316362_1317268_-\|Alkaline-phosphatase-synthesis-sensor-protein-PhoR	unknown	unknown	gnl\|CDD\|223715
CP035945.1\|QBE95715.1\|1328037_1329345_+\|Phosphomethylpyrimidine-synthase	unknown	unknown	gnl\|CDD\|376689
CP035945.1\|QBE95710.1\|1320814_1322080_+\|Sulfopropanediol-3-dehydrogenase	unknown	unknown	gnl\|CDD\|376389
CP035945.1\|QBE95713.1\|1324704_1325592_+\|HTH-type-transcriptional-activator-RhaR	unknown	unknown	gnl\|CDD\|225117
CP035945.1\|QBE95704.1\|1312981_1315609_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223650
CP035945.1\|QBE95717.1\|1329561_1330212_+\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|236320

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE95709.1\|1319845_1320745_+\|Formamidase	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	8.37694e-83
CP035945.1\|QBE95705.1\|1315605_1316289_-\|Bacitracin-export-ATP-binding-protein-BceA	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.68024e-107
CP035945.1\|QBE95707.1\|1317269_1317941_-\|Transcriptional-regulatory-protein-YycF	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.43072e-76
CP035945.1\|QBE95718.1\|1330242_1331010_+\|Thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.28186e-144
CP035945.1\|QBE95712.1\|1323565_1324606_+\|Low-specificity-L-threonine-aldolase	gnl\|CDD\|224919	COG2008, GLY1, Threonine aldolase [Amino acid transport and metabolism].	4.41654e-93
CP035945.1\|QBE95714.1\|1325721_1327719_+\|Alpha-xylosidase-BoGH31A	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	3.4846e-178
CP035945.1\|QBE95703.1\|1311114_1312842_+\|hypothetical-protein	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	6.18643e-15
CP035945.1\|QBE95716.1\|1329362_1329560_+\|Sulfur-carrier-protein-ThiS	gnl\|CDD\|340451	cd00565, Ubl_ThiS, ubiquitin-like (Ubl) domain found in sulfur carrier protein ThiS. ThiS, also termed Thiamine biosynthesis protein (ThiaminS), is a sulfur carrier protein involved in thiamin biosynthesis in prokaryotes. It has the beta-grasp ubiquitin-like (Ubl) fold with low sequence similarity to ubiquitin (Ub), and is activated in an ATP-dependent manner by sulfurtransferases, similar to the activation mechanism of Ub-activating enzyme E1. ThiS has common evolutionary origin with Ub-related protein modifiers in eukaryotes, a beta-grasp fold as Ub, and is closely related to proteins MoaD and Urm1.	8.70964e-21
CP035945.1\|QBE95721.1\|1332802_1333798_-\|hypothetical-protein	gnl\|CDD\|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	1.83719e-87
CP035945.1\|QBE95720.1\|1332207_1332792_+\|Thiazole-tautomerase	gnl\|CDD\|238317	cd00564, TMP_TenI, Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.	1.44954e-54
CP035945.1\|QBE95711.1\|1322124_1323276_-\|hypothetical-protein	gnl\|CDD\|133404	cd04777, HTH_MerR-like_sg1, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 1), N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.96815e-17
CP035945.1\|QBE95708.1\|1318370_1319819_+\|Malate-2H(+)/Na(+)-lactate-antiporter	gnl\|CDD\|188097	TIGR00931, Uncharacterized_Na+/H+_antiporter_HI_1107, Na+/H+ antiporter NhaC. A single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of the NhaC family are found in both Gram-negative bacteria and Gram-positive bacteria. Intriguingly, archaeal homolog ArcD (just outside boundaries of family) has been identified as an arginine/ornithine antiporter. [Transport and binding proteins, Cations and iron carrying compounds].	6.12995e-136
CP035945.1\|QBE95719.1\|1331024_1332185_+\|2-iminoacetate-synthase	gnl\|CDD\|236425	PRK09240, thiH, 2-iminoacetate synthase ThiH.	0
CP035945.1\|QBE95702.1\|1309279_1310581_-\|Zinc-binding-GTPase-YeiR	gnl\|CDD\|349766	cd03112, CobW-like, cobalamin synthesis protein CobW. The function of this protein family is unknown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterize it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage caused by mitomycin. YijA gene is a homologue of the CobW gene which encodes the cobalamin synthesis protein/P47K.	2.88592e-53
CP035945.1\|QBE95706.1\|1316362_1317268_-\|Alkaline-phosphatase-synthesis-sensor-protein-PhoR	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.64085e-46
CP035945.1\|QBE95715.1\|1328037_1329345_+\|Phosphomethylpyrimidine-synthase	gnl\|CDD\|376689	pfam01964, ThiC_Rad_SAM, Radical SAM ThiC family. ThiC is found within the thiamine biosynthesis operon. ThiC is involved in pyrimidine biosynthesis. ThiC participates in the formation of 4-Amino-5-hydroxymethyl-2-methylpyrimidine from AIR, an intermediate in the de novo pyrimidine biosynthesis. Thic is a member of the radical SAM superfamily.	0
CP035945.1\|QBE95710.1\|1320814_1322080_+\|Sulfopropanediol-3-dehydrogenase	gnl\|CDD\|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0
CP035945.1\|QBE95713.1\|1324704_1325592_+\|HTH-type-transcriptional-activator-RhaR	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.55839e-28
CP035945.1\|QBE95704.1\|1312981_1315609_-\|hypothetical-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.40434e-08
CP035945.1\|QBE95717.1\|1329561_1330212_+\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|236320	PRK08644, PRK08644, sulfur carrier protein ThiS adenylyltransferase ThiF.	4.47642e-103

>CP035945.1|QBE95711.1|1322124_1323276_-|hypothetical-protein
MLHISQDTIRYYMELGLIVPGRHGNLYDFSGDSIEDIRWIHKLKEMGFLLKEIQKVLSLRRTSNWVEPQEIAEYLILLDKKKKSLRGEIENIKEEIIRIEEEEKSFTIETAGDKVLVGVPLKALEYLRCPFCQEAFAVEQVQMNSRYIYNGKLTCSCGYALEISDGIVLSPGAADESDGGADLEREKYKDLPASVVTMLQRSYNFLLHRVSGLQLYDRVVMETDINEFFYLYTHFRKIENRVLFIITDRYPQVLRMYKERIEYLKLDLDILYLADGSGNYPLKKESVDLFIDYFSSNYCKVRRGESLPGRMAEYLKENGEMIGCYFSGKDRERFFDKKQFLGDIREKGYALVKERTIDCPVEVGKENQLLLYESKRQANNREG
>CP035945.1|QBE95710.1|1320814_1322080_+|Sulfopropanediol-3-dehydrogenase
MEYLKKAKPADRQRQQDLEAEVHAIIRDVSARGDRALIEYNTQFDGNTRTSLRISPEEIRRAYNLTSPELIRDLKVTAQRLEDFALKQKASLHGFSDYEISPGIFLGQKIIPVDSCCCYVPGGGYPLYSTALMMGITARTADVRRIAMCTPAVNGTDSVHPSTLVAMDIAGIHEIYALSGAHAVAAFACGTEQIQPVDMIVGPGNQYVTEAKRQCYGRIGIDFLAGPSEILVIADREADPCCIAADLLSESEHDPQSIARLITTDRELGLEVIRQVEMQLPELETEDIASAAWNLCGEVILADSLDEACSLANAFAPEHLVLHFADAETHTDGFKNYGSLFIGKYSAVVYSDYVNGINHTLPTGKAARYSGGVWIGTFSRVCTTQRLTKEAAQQISALASHLAEGEGFPGHANAASMRMKS
>CP035945.1|QBE95709.1|1319845_1320745_+|Formamidase
MKNLNRDQVIYTMSREHRPVLTVKSGETVTVHTYDCFKDRLVPEDSSFDSLLFDELNPATGPIFVEDAKPGDTLRADILDISLAPLGVTEIDPEFGCLAKLVKNPVVKRLPIENGKIIFSPRLSLDLKPMIGVIGVAPADRDIPTDTPDSHGGNMDCTQIKTGASVYFPVSAKGALLSLGDLHACMGDGEIGGCGVEIAGEVTLKLTVIPTYQKPYPVVVTDNEVMAVASCKTVDEAWQKAVEYLHDYMVSETELTSDEAVMLQSVAADLSICQTVNPNKTVRMSIPLKYLEAYGYRQK
>CP035945.1|QBE95708.1|1318370_1319819_+|Malate-2H(+)/Na(+)-lactate-antiporter
MNAKEKVKKEPTLLLALTPVVLTVIILIFSVSVLKVDVQVPLILGTCITAFIAIVFLGYTWQDLEDGAVESLKSIMQAVLLLIIIGATIGTWIVGGVVPALVYYGLQILTPAFFLVACMILCSIVSLAAGGSWATVGTIGIALVGIAKGLDIPVGLAGGAIISGAYFGDKMSPLSDTTNLSAAIAGAKLTDHIKHMMYTTAIAYGISIVGFGIIGFRFAGQELDHGQINGILDALASNYNITPWLLLVPVIVIVLIALKVPAIPGLFAGTVLGMLCGVIFQHQDLSIVFNAVQNGVVVETGHAMVDELLTRGGLMSMMWTVSLIICALSFGGILECTGMMSVIANKLLEFAKSTGSLVLVTIISALFCNVLLGDHCIAIAIPGRMFKDEYRKRGLAPRNLSRVLEDAGTVTSPLIPWNTCGATMSGFLGVPTLTYLPYCFFNILCPVISAIFGFTGLTIMKLEDDPSSDQYVEKKGKHLAKE
>CP035945.1|QBE95707.1|1317269_1317941_-|Transcriptional-regulatory-protein-YycF
MNKLLIVEDDRDLLEGLAFSMESEGYQVICASTMEEGLKKFRESCPDFIILDCNLPDGTGYGFCREVRKTSQVPVLMLTARDTEMDEIQALETGADDYMSKPFSLAVLKTRIKKQLKRKDAEFIRFSNGFYIDRSTCRVLRGDREISLSTVEYRLLTYLIDNKGRIVSKEQILAHVWDSEGRFVDENAVSVNIRRLRQKIEDDPDEPVFIRNIRGMGYIWKEI
>CP035945.1|QBE95706.1|1316362_1317268_-|Alkaline-phosphatase-synthesis-sensor-protein-PhoR
MEAVLLGIAVLCIGFALWERYRSRKMYREIDRMMDEILSAKPVTISDLKEGPLSALSYKARRLQERQDLEMSGASKEKEQVKMLVSNMSHQLKTPLANVRMYGEILENQKLSEEQRKHFLEKLRRQTEKIQWVLNSLLKMVRLEQDVITFEGKDADIKQTLLQAVNSIYEKAEKKQIQIQVEEFPSLYLWHNPSWTAEALENILENAVKYSPPQSRIMICIKSYEMYSELQISDQGPGIDKTEETEIFKRFYRSPKVSGEEGSGIGLYLVKLILEKEKGYVTVNSKPGCGSTFSVFLQNCK
>CP035945.1|QBE95705.1|1315605_1316289_-|Bacitracin-export-ATP-binding-protein-BceA
MILQVKDVTKIYGQDENAVKALNGISLEIEQGEFAALVGTSGSGKSTLLNLIGGLDVPTEGKITIRDREIQSLKRGELTIFRRRNIGFVFQNYSLMPVLNVYDNITLPVTFDKGKHVDHQYIKELLKDLGLWEKRKKYPDELSGGQQQRVAIARALANKPAVILADEPTGNLDSKTTMEVMGVLKASSDKYHQTILMVTHNEAIAQTCDRIIRIEDGRVYERGGAWV
>CP035945.1|QBE95704.1|1312981_1315609_-|hypothetical-protein
MRTAAKLAWQYSRFYLRQTLSIFFSILLSMALLGGISSLLYSGRSSSREKARETGGDWHYYVNADQKMREEIDKHPKGKGYELKRIGHIETKAVMGEPYVISLNYGDRSYMDIMGRTLEEGEYPKQQDEIALDAYTISNLQVEKKLGTQVTLGEKTYTLCGIVKSRPANSGEEMMAFVSEDTPDETGETRLYLRFDEGKKVYKQLEALADHFEIPLEKLKRNNDLTAYVEGTIPAAFVHIIKTGLRLPEGKFTYILSSILRDNPGTNGNVISVVLILFSVFIISSIYRISLQKRISQYGVLNVLGIGGIRLFQMMFLELWGIFLIGYPVGSLLGNLGARALYSRFSRVFTGEDTVPGSFMTDVDSLVKNFAVMSVLLVLVSMALCRKLIKMNLMQILRKNPAKQRSRKIYSLKTENMPEVLTKKFMFERKSVFVGILFSLSLGGIIFLGTTYMTANTKANNMLTMKADDGLGSDMLLYEESNDLSQVIPEDTAEELKKIRGISRVLPTSYLLGEIPVKRQDFKWLTYYPEIGVKYEPECGENISQRNMELYGGRAVEDADGDFRLKTNVYGYEPEMIRKLSDYLLEGTIDPETLEKENAVILQTIMDGQGNYDGLKIQPGDTITLKVPKDQKVPEEVYKFQSGEEWYQEKEFTVAALVNRTMAKTDFYIGSSPDNLSLIFTNKQMKDNFGVEGYQIISMEKASASDAYGAEKQVREVTSSVPHCVLKDYTADIARENTFLKQKMLFFYGVGVILLIISVLHIMNSISSMVLSRRHEFGILRAMGISDRGYMLMMLKEALRYGIYASLVMGAGYVLARRFLLYMMQKVYLFVLPKEEVSVWLILGLTAVNILLSMAAVAMPVRAVLKDSVVEEIRR
>CP035945.1|QBE95703.1|1311114_1312842_+|hypothetical-protein
MNLHITKSKNAESFYIAKSFAKANGGTSSTIVRKLGTLDQLLVEHGPTRDDVLAWAKNEVKIETEKYKKEKEAKTVLIPFHADRQLDYEKQVFYRGGYLFLQYIYYQMQMNKICRKLKSKYKFKYDMNAILADLIYARILEPSSKRSSYKTASEFLEKPSYELHDVYRALDVLGNECDFIQSEVYKNSHFLGTRNDKILYYDCSNYYFEIEQEDGIKKYGKSKEHRPNPIIQMGLFMDGDGIPLAFSLFPGSANEQTSLKPLEKKVLGEFGCQKFIYCSDAGLGSEDIRAYNHMGERSYIVTQSIKKLKKEEKEWALNPQGFKRISDDTPVDITQLSEDDKGLYYKDGPYTTKKLHQRLIITYSPKYAFYQKTLRSKQVERAQKMLDAGKTKKNRKNPNDPARFIGTLAATKEGEAADIHHYLDENKIAEESKYDGLYAVCTDLLDDKVGDILKVSEGRWQIEECFRIMKTDFSARPVYLQDENRIKAHFLICFLSLMLYRFLEKKLDSKYTCEELLDTLKSMNFVNVQEQGFIPTYKRERITDALHDACGFRTDYQFITKSTMKTIQKKSKGRE
>CP035945.1|QBE95702.1|1309279_1310581_-|Zinc-binding-GTPase-YeiR
MTKIDIFSGFLGAGKTTLIKKLLKEAYSGEQVVLIENEFGEIGIDGGFLKEAGIEIREMNSGCICCSLVGDFGEALKEVIQKYQPDRIIIEPSGVGKLSDVIKAVKKVEGEVDIKLNSFTTLVDVMKCKMYMKNFGEFFSNQIEYAGTIILSRTDKSTEEKVIAALQLIRGLNKSAAVITTPIEKLSGAKILDTMENNRSLEKELLEEEVCPVCGGHHDHEHHHQEECDHEHHQEECDHEHHHDEECGCEHHHGEECGHEHHHGEECGCEHHHGEEGSHEHHHGEECGHEHHHGEECGHEHHHENECSCEHHHGEEGGHEHHHDGECGCGHDHHDHHHHHADEVFTSWGRETAKTYTEEEIRTILEALSDDEEYGMILRAKGMVEGKNGGWVYFDMVPGEADVREGSPEYTGRICVIGSKLREDSLEKLFKLV
>CP035945.1|QBE95712.1|1323565_1324606_+|Low-specificity-L-threonine-aldolase
MYSFQNDYSEGAHPNILRALETINYHQNNSYGLDEHSDNARELIQESLEDYSVDIHFIAGGTLTNLTFISHILRPYEAVLSADTGHINTHETGAIESTGHKVFSIPTEDGKLTPDFIRPVLKLHENEHWVEPRLVYISNPTEVGTVYTKEELETLYAFCKRHDLYLYMDGARLSMAMAAEETHLTFPDLPNLCDAFYIGGTKVGAMFGEALVIVKEEFKDHFRFNMKQHGAILAKGWMMGVQFEELFRDGLYLELGRKGVAMAQILKEVFEKTGIPLLAPAPTNQVFPILPDALAEAVNERFLTTFQCKPDKDHTCLRFCTSWATNEEAVRDFASEFEDLAAKFNR
>CP035945.1|QBE95713.1|1324704_1325592_+|HTH-type-transcriptional-activator-RhaR
MKINPSVNDSLKERAAHGSQEFPLQVYQDMEYCENGLILYNHWHEEAEILFVTEGMMELAVDGISILAGKDTIVLIPPNLLHVAYQYQNQKCRFSSIVFHPDFVSSKNRDIIQAQQLDPFFENSFVSSYVIYGTDLKSETVRGLLRELTASYLASNPYRELLIKGYLYQILSHLLIKEEKHNIKSMSDYINEERKKKILKYIDENYQNPLSLDALAGSVSLSREQFCRFFKKSFRSTPISYLNRFRINRSMALLKETSLPVIDIAIAVGFDSSNYFAISFRKATGMTPSQYRNMT
>CP035945.1|QBE95714.1|1325721_1327719_+|Alpha-xylosidase-BoGH31A
MSFFTKSENYIEYHNAGETLRIAAWGENSLRVVSVPSGPLDMSSSALKDQAPVNVQIQTDEETAVIKNGKISALIDTRGWNSAAVVTFFNDKNEILLKEMDGGGALIRRARKFSPYIGGDFRLKVTFEANKDEKIYGMGQYQQDILDLKGCNIELAHRNSQASIPFYVSSKGYGFFWHNPAIGSVSFGKNVTEWRADSTKKMDYWITAGDTPAQIESQYSQVTGRAPMMPECGLGFWQCKLRYHNQEQVLSVAREYHRRGIPVDVFVVDYYHWPRCGDYRFDENFFPDPKAMAEELRSYGMELMVSVWPQIDWRSENFQEMRQKGLLVQTEHGLNVQMDFQGNNVFYDATNPEAREYVWDKCKKNYAENGIKLFWLDEAEPEYTTYDYENYRYYAGSVMQQGNIYPREYARGFYEGQKKNGQEDVLNLVRCAWAGSQQYGALIWSGDIHSTYQDFRNQIVAGLQMGLSGIPWWTTDIGGFHGGNIYDKDFQELLIRWFQFGAFCPVMRLHGNRLPRTPLYKANGEETEGTGADNEIWSYGEENYQIMKKFIEIREMMRDYTRSLMAKAHETGAPVMRTMFYEFPEDTRTWELDTQYMYGSDILAAPIVEPHAMSRKVYLPSGCTWTNAHTGEILQGGQWIEAEASIDTIPVFLRDGRQEYLIKNI
>CP035945.1|QBE95715.1|1328037_1329345_+|Phosphomethylpyrimidine-synthase
MQYTTQMDAARKGIITKEMQAAAKKEQMDVRQLMALMAKGQVIIPCNKRHTSLEPNAIGSMLRTKINVNLGISRDCKDMDMEIEKVNNAVKMGAESIMDLSSYGDTRTFRRRLTKECPAIIGTVPIYDAVVYYHKPLKEITSRQWLDIVRMHAEDGVDFMTIHCGINKETAGKFKRNKRLTNIVSRGGSIIFAWMEMTGQENPFYEHYDEILDICREYDITMSLGDACRPGCIQDASDISQIEELITLGELTKRAWEKDVQVMVEGPGHMPLDQIEANMKIQQTLCQGAPFYVLGPLVTDVAPGYDHITAAIGGAIAATYGASFLCYVTPAEHLRLPNLDDVKEGIIASRIAAHAADIAKGVKGAADWDRKMSTARKNLDWEEMFRLCLDPKKAGRYRAEAKPEKEDTCSMCGNFCAVKNMNRILDGEIVNIYDE
>CP035945.1|QBE95716.1|1329362_1329560_+|Sulfur-carrier-protein-ThiS
MIKINGTPVQLSAPCTVETFLLEQGYTLQRIAVERNGEILPKKHYADTLVLENDTYEVVSFVGGG
>CP035945.1|QBE95717.1|1329561_1330212_+|tRNA-threonylcarbamoyladenosine-dehydratase
MEEGHHILSKSEMEEVLAERHTLPIYRKLKRSGAAIAGLGGLGSHVAVMLARTGIGSLHLIDFDRVEPSNLHRQAYKMKHLGRYKTDALREEISEINPYISVRTDTVKLTPDNIGSLLADDRIICEAFDRAENKAMLVNHLLEHRPDAVIVSGSGMAGFGSSNTIHTKKRMKNLYLCGDGTSDTASGISLTAPRVTLCAAHQANMILRIILGETDV
>CP035945.1|QBE95718.1|1330242_1331010_+|Thiazole-synthase
MRDDKLILGGHEFHSRFILGSGKYNPELIRAAIENAGAEIITLAVRRANSGTASILEHIPDNVTLLPNTSGARTADEAVRIARLARELGCGDFIKVEVIRDSKYLLPDNQETIRAAELLANEGFIVMPYMYPDLNTARDLANAGAACIMPLGSPIGTNKGLCTKEFIKILIEEIDLPIIVDAGIGRPSQACEAMEMGADAVMANTAIATAGNIPAMAEAFKKAVEAGRTAYLSGLGRIINGSASASSPLTGFLEQ
>CP035945.1|QBE95719.1|1331024_1332185_+|2-iminoacetate-synthase
MTARRTDHMEYMDGMEALDSDILDKVIHAMDHYDPNTFTETHVRTALSHDIRTPGDFAALLSPAAEPFLEEMAQAAQAETRKHFGNCINLFTPLYISNYCENHCIYCGFNCHNHIRRARLTPEEIDQEMAAIAKTGLEEILILVGESRAKSDVAYLGEACRIARKYFKMVGLEVYPMNSDEYAYLHKCGADYVTVFQETYNSDKYETLHLAGHKRVFPYRFHAQERALKGGMRGVAFGALLGLDDFRKDAFATGMHAWLLQRKYPQAEISFSCPRLRPIINNDKINPKDVHEPQLLQVITAYRLFMPFAGITISTRERAGFRDQVITIAATKISAGVSTGVGGHVEDLEDKGDDQFEISDDRGVEEVYQAVLKKGMQPVMNDYVFV
>CP035945.1|QBE95720.1|1332207_1332792_+|Thiazole-tautomerase
MFPYGNMLAVTNRHLCDGPFLAQVERVAAKKPRGIILREKDLEASEYLELAEKVQKICRKYGVACILHSRIETAQRLACSAVHLPFSGFCSLSDKGNVLEGFDTVGVSVHSVKEAVAAERLGAGYVTAGHIFLTDCKKGLPAKGIPFLKNVCTAVRIPVYAIGGINPDNVKDVLDAGAAGFCVMSGIMRGPLWR
>CP035945.1|QBE95721.1|1332802_1333798_-|hypothetical-protein
MQILDMHCDTISKIRQMKKEGEHISLHQNPLSVDLEKMREGGCTLQTFAIYVNWKEEPDAAEAAKDILNIFRQEMDQNADMISQITTYSQLEENIKAGRMSALLSLEEGAIYQESADTLRWFWEQGARMATLTWNYENDLGYPNCMGDPFTQRIWSWGEERGLKEKGLQFLEELEHLHMLVDVSHLSDGGFWDVARHATRPFLASHSNARGLVKGAARNLTDEMIRALAGRGGVMGLNYAVSFMRPDWKPGEDGTTVKEIIRMAEYILNIGGSECLGLGSDYDGILELPEISHCGRLQFLAEKMEKYGFTYSQVEKIMGGNVKRFLKENLD

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Crispr_ID: CP035945_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_4

2118513-2118600

Orphan

Consensus_repeat	Method
TAGTGAGAGGCAATAATCGAGTATTATTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035945_4

>merge|CP035945|4|2118513-2118600|CRISPRCasFinder
TAGTGAGAGGCAATAATCGAGTATTATTGCCTCAATTACCATACCGAAGTAGGGGGAATAGTGAGAGGCAATAATCGTGTATTATTGC

>CP035945|4|4|2118513-2118600|CRISPRCasFinder
TAGTGAGAGGCAATAATCGAGTATTATTGC	CTCAATTACCATACCGAAGTAGGGGGAA
TAGTGAGAGGCAATAATCGTGTATTATTGC

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE96331.1\|2126174_2127476_+\|Folylpolyglutamate-synthase	unknown	unknown	gnl\|CDD\|223362
CP035945.1\|QBE96320.1\|2111489_2113226_+\|putative-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
CP035945.1\|QBE96322.1\|2115119_2115719_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379417
CP035945.1\|QBE96335.1\|2129750_2130194_+\|Anti-sigma-F-factor	unknown	unknown	gnl\|CDD\|179626
CP035945.1\|QBE96334.1\|2129436_2129736_+\|Anti-sigma-F-factor-antagonist	unknown	unknown	gnl\|CDD\|131932
CP035945.1\|QBE96333.1\|2127629_2129267_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
CP035945.1\|QBE96319.1\|2109703_2111395_+\|Sensor-histidine-kinase-YehU	unknown	unknown	gnl\|CDD\|225519
CP035945.1\|QBE96328.1\|2119908_2120115_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|365990
CP035945.1\|QBE96325.1\|2117240_2118110_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE96324.1\|2116356_2117244_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227053
CP035945.1\|QBE96326.1\|2118317_2118506_+\|Phage-shock-protein-C	unknown	unknown	gnl\|CDD\|377200
CP035945.1\|QBE96329.1\|2121105_2123754_+\|Valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
CP035945.1\|QBE96321.1\|2113228_2115007_+\|putative-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
CP035945.1\|QBE96332.1\|2127468_2127618_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE96317.1\|2107834_2108899_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378582
CP035945.1\|QBE96323.1\|2116036_2116360_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224609
CP035945.1\|QBE96336.1\|2130205_2130919_+\|RNA-polymerase-sigma-F-factor	unknown	unknown	gnl\|CDD\|180137
CP035945.1\|QBE96327.1\|2118713_2119709_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131955
CP035945.1\|QBE96318.1\|2108931_2109711_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223767
CP035945.1\|QBE96330.1\|2123782_2125951_+\|Lipoteichoic-acid-synthase-2	unknown	unknown	gnl\|CDD\|293739

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE96331.1\|2126174_2127476_+\|Folylpolyglutamate-synthase	gnl\|CDD\|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	3.79958e-126
CP035945.1\|QBE96320.1\|2111489_2113226_+\|putative-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.68433e-160
CP035945.1\|QBE96322.1\|2115119_2115719_-\|hypothetical-protein	gnl\|CDD\|379417	pfam14014, DUF4230, Protein of unknown function (DUF4230). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 203 and 228 amino acids in length.	3.49687e-26
CP035945.1\|QBE96335.1\|2129750_2130194_+\|Anti-sigma-F-factor	gnl\|CDD\|179626	PRK03660, PRK03660, anti-sigma F factor; Provisional.	1.52644e-70
CP035945.1\|QBE96334.1\|2129436_2129736_+\|Anti-sigma-F-factor-antagonist	gnl\|CDD\|131932	TIGR02886, Anti-sigma_F_factor_antagonist, anti-sigma F factor antagonist. The anti-sigma F factor antagonist, also called stage II sporulation protein AA, is a protein universal among endospore-forming bacteria, all of which belong to the Firmcutes [Regulatory functions, Protein interactions, Cellular processes, Sporulation and germination].	5.12626e-27
CP035945.1\|QBE96333.1\|2127629_2129267_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.54878e-05
CP035945.1\|QBE96319.1\|2109703_2111395_+\|Sensor-histidine-kinase-YehU	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.27662e-44
CP035945.1\|QBE96328.1\|2119908_2120115_+\|hypothetical-protein	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	2.1474e-06
CP035945.1\|QBE96324.1\|2116356_2117244_+\|hypothetical-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	8.38224e-11
CP035945.1\|QBE96326.1\|2118317_2118506_+\|Phage-shock-protein-C	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	1.96203e-24
CP035945.1\|QBE96329.1\|2121105_2123754_+\|Valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
CP035945.1\|QBE96321.1\|2113228_2115007_+\|putative-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.02061e-176
CP035945.1\|QBE96317.1\|2107834_2108899_+\|hypothetical-protein	gnl\|CDD\|378582	pfam11175, DUF2961, Protein of unknown function (DUF2961). This family of proteins has no known function.	2.27641e-113
CP035945.1\|QBE96323.1\|2116036_2116360_+\|hypothetical-protein	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	2.72852e-14
CP035945.1\|QBE96336.1\|2130205_2130919_+\|RNA-polymerase-sigma-F-factor	gnl\|CDD\|180137	PRK05572, PRK05572, RNA polymerase sporulation sigma factor, SigF/SigG family.	8.45861e-108
CP035945.1\|QBE96327.1\|2118713_2119709_-\|hypothetical-protein	gnl\|CDD\|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	7.26624e-47
CP035945.1\|QBE96318.1\|2108931_2109711_+\|hypothetical-protein	gnl\|CDD\|223767	COG0695, GrxC, Glutaredoxin and related proteins [Posttranslational modification, protein turnover, chaperones].	0.00591482
CP035945.1\|QBE96330.1\|2123782_2125951_+\|Lipoteichoic-acid-synthase-2	gnl\|CDD\|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	1.71786e-67

>CP035945.1|QBE96326.1|2118317_2118506_+|Phage-shock-protein-C
MSDKRLYRSSTNYMLAGVCGGIAEYFNIDPTLVRLAWVILSCFGMVWTGIVAYIIASIIIPK
>CP035945.1|QBE96325.1|2117240_2118110_+|hypothetical-protein
MKKFTKFCMIAALVLVIVGGALFLSGLVMGATWDGVTTAAENGFNWAPFRNWIRSDNDFNFTESIDDIKETMNGKAVKEYEFDADQVIDLDVDTKYAYVSVIRSSAKDKIRVRVYSNKDKVEFDQDDGQLSIERSYRRRSIEKYPIQIEIPENKRFEDAEFQIGAGMLEVQDLQAESLIMYVGAGTVDTSGIIRADDAELGTGMGTMDIAFIDFNTGSVDCGMGTMTAKLAGKRKDYRTDLDCGLGSVTIGSESHSGISSLETGDSNAQKYMEIECGMGTVDILFENGD
>CP035945.1|QBE96324.1|2116356_2117244_+|hypothetical-protein
MNRKEFLAQLERLLWDIPVQEREEALEFYNSYFDDAGEENESSVIQELGSPGKVAAIIKADLGESRKEYGEYTETGYSDGIFDDRNMPERAGAESKKDDTDKEGETQKDSQYGGPRGYGSQNGSGQESSGQGSFRKDGTDSQYGNGGRGYDGPYSRSGYRSEKSRTNRSGLMWGIIIIFIILAIPVVGGIGIGILGLPIGLVAGAAGIIAAIFGCGVGLLGGGIAMVVYAMIHMLGNPAAALAFSGVGMIMSAVGILLVMVFVLVVAKVLPAVFRWVIDLIQRIIHRGKRGGDHS
>CP035945.1|QBE96323.1|2116036_2116360_+|hypothetical-protein
MVFNTGAALLDAIVLAVVSKETEGTYGYKITQDVRQVLEVSESTLYPVLRRLQKDECLETYDQEYGGRNRRYYKLTERGMAQLNLYKTEWKNYSTKISRLFEGGIPK
>CP035945.1|QBE96322.1|2115119_2115719_-|hypothetical-protein
MKNKIARVIGVVCVLILVVFGIFLGRYWEGRKYQKADISVSAITARLTQASDLATARLEYRGLIRYEAGEIRFITQKGFTMIYDAHIKAGIDLSKAQVDVSGETITVTLPKAVIQDVVIDPDSLEFYDEKIALFNPQNKEDTVTALQAAKEDAEKNAADSDLLTTADEQARRLIQELLTPVTQDSDKEYNIVFSQQTEN
>CP035945.1|QBE96321.1|2113228_2115007_+|putative-ABC-transporter-ATP-binding-protein
MDKKKSAQKETLLKVLKYVRHYWPFLILSVAAAAVTVALTLYVPILTGEAIDYIIDKEKVDFAHVLLTLEKIGIVILFTALAQWIMNVSNNKMAYHTVQDVRNQAFQKIQILPLKYMDDHSYGEVVSRVIADVDQFSDGLLMGFTQLFTGVITILGTLLFMLTRDVGITLVVVLITPLSLFVANFIAKRTFIMFKQQSEARGDQTALVEEMIGGQKVVQAFNYEEEALEHFDKINQRLADCSLKAIFFSSLTNPCTRFVNSLVYAGVGLVGALSVINGGITVGQLSCFLSYANQYTKPFNEISGVVTELQNALACASRIFALIEEEPQIPEPENVEDLKHTDGKVDLEHVYFSYSPETKLVQDFNLHVQPGQRVAIVGPTGCGKTTVINLLMRFYDVDSGSIRVSGRDIRSITRESLRGSYGMVLQDTWLRTGTIRDNIIMGKPDASEEEIKAAARASHAHSFIKRLPKGYDTVITEDGGGLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTRTEMHIQEAFASMMQGRTSFIVAHRLSTIREADVILVMNNGNIVEQGDHKSLLEKNGFYAALYNSQFLTGQDTPVAAE
>CP035945.1|QBE96320.1|2111489_2113226_+|putative-ABC-transporter-ATP-binding-protein
MRKLLIYMKDYKKESVLAPLFKLLEASFELLVPLVMARIIDRGIGNGDRHYVTVMCLLMVSLGVIGLVCSATAQYFAAKAAVGFSTKLRHVLFSHIQGLSFTEMDTMGTSTLITRMTSDINQVQNGVNMVLRLFLRSPCIVFGAMIMAFTIDVKAALIFVVTIPLLSVVVFGIMLITIPLYKKTQAALDRVLGITRENLTGMRVIRAFNKEEEEKERFQESNDTLTAMQKHVGKISGLMNPMTYIIINGALVVLLWTGAIRVNTGYITQGQLIALVNYMSQILVELIKLANLIITITKALACANRVESVLEIQSSMQDAGKKTPEKAEENSPSVEFCHVGLAYKNAGEESLTDIDFRAEKGQTIGIIGGTGSGKSSLVHLIPRFYDVTAGEVRVNGVDVRKYPIHELRQKVGMVLQKATLFKGTIRENLLWGNRGASDEELWRALEISQAKEFVDKKEDGLDTEVVQGGKNLSGGQKQRLTIARALVKNPEILILDDSASALDFATDARLRRAIGNLKDKMTVFIVSQRASSVMYADRILVMEDGRLAGMGTHRELMETCSVYREIYESQFESRQEEA
>CP035945.1|QBE96319.1|2109703_2111395_+|Sensor-histidine-kinase-YehU
MSKLKLNRPRTLWIKTILIFLTGGIFICVLFSILYYRTVKIMTEKTNLLFENTVYQVSERCSQETGQMEDLILGISENQWVKNYLSGLLSGTDNFSMTEVRIVREALRERNLSMAENVYVYTKDYEPINCFYRNAVFDTAEPYKTFLEEYRELPNGNILWRYPEGEPRMMEAVSYIHDGDIVYGLLAVQFTQDSFETLFRAKNKSRQEKMLLTDADGRILFTEDRDLIGRYLKTQGEEEEHHVVYPLGSFGWNLCGILESTAVTQELNKIIPILIIVFLCIVLLVGIIALTIFKSFLRPVKQLLYGMERIQNGELDFTMERKKQDEFGMIIDNFNYMLVRIKELLHTVQRQRNNYYKLEMLALKSKLNPHFLYNAFDMIYWKMVLKNEYEIADVVATLADILRYCVNHKKEFVTVQEDMRYLSSYLSFQRLLLNEKLQYEIDIPEELSECVMPKLLIQPLVENAIKYGIDEQGGEIWVSLRREGDHLIFDVRDNGKGMTQETCRDLLRDDAGDKGGFGVRLVKAMVKSTYGEECGVSIYSREGWGTKVTVKILKDVPVPEYIR
>CP035945.1|QBE96318.1|2108931_2109711_+|hypothetical-protein
MLGAVLLLLLAGGAYAVWEINRIPVPVSCYIYDQCGGCSVTDHPCNACTGERQYRIRMENMLEEAGVRDQVDLKIYNVLYSFYRNNLTKAMEAASEPAEMTYPAVFAGSTMLLGQDEVEAKLLSAIREEGAWQKKLGYLLGINKETHMGSREISRIVFFTMEGCPDCQEAKEWLDARNGELGGKLYEKFDFYPVGSEEPGSWEMLKKFYILHGREQESLWVPTIAVNDRCLIGMDEIRNYFEHYDTDEKIRTEVPKDYE
>CP035945.1|QBE96317.1|2107834_2108899_+|hypothetical-protein
MIGDMSSLSKMQDIRTRSVSPENFTGEKGAGGQATEGTGASCARDLGKGWKVSPSVQIEPGQTFTLADIKGQGMVKHIWVTTSSMQNRTLVLRMYWDNREFPSVEAPLGDFFASADEQQYEQLTSLAVCVNPRRGLNCYWDMPFYEGCRMTLENLAEEPVIVYYQIDYQLRELEEGHGYFHAQYRRTNPLPYKEDYTVLDGVKGKGQYVGTYMFWGVNNNGWWGEGEIKFFMDGDREYPTICGTGTEDYFCGAYDFEVDGVYRPYCTPYAGLSKITNTDGAYKTQQRFSMYRWHITDPVYFDEDLKVTIQALGWRSGGRYLPLQDDISSVAYWYQDRPAPSGSVLGSRDDMEII
>CP035945.1|QBE96327.1|2118713_2119709_-|hypothetical-protein
MKHKILPGFLAVAVVSAMGIAPVRVQAASSIEDVKQNLKSKGIVVAGNVSNLDELKQKLESMGIDCSIPGWLVSLCPELPGNGQPEMPDSPDDNQPENPDIPDNEQPENPDIPDNEQPENPDTPDSEQPETPDSPDNEQPEMPDTPDSEQPETPDSPDNEQPEMPDTPDSEQPETPDSPDNNKPETPDSPDNNQPENPSLPDTDTENADFVRQVVDLVNRERAKAGLSPVTADTSIQAAAQVRAKEIEKSFSHTRPDGSSFSTALTQQGVTYRGSGENIAWGQKTPEQVMNGWMNSEGHRANILNKNFTKIGVGYHQNASGTNYWTQLFTY
>CP035945.1|QBE96328.1|2119908_2120115_+|hypothetical-protein
MSKKNDEKIDLNKIPRDEMLKYEIAEELGLLDQVLESGWKSLSAKETGRIGGIMTRRKRESKKAESTS
>CP035945.1|QBE96329.1|2121105_2123754_+|Valine--tRNA-ligase
MSKELAKTYDPKGLEDRIYQKWLDNKYFHAEVNRDKKPFTIVMPPPNVTGQLHMGHALDETMQDILIRFKRMQGYEALWQPGTDHAAIATEVKVIEKLKAQGIDKNEIGREEFLKHAWEWKEEYGGKIINQLKKLGASADWDRERFTMDEGCSQAVQEVFIKLYEKGYIYKGSRIINWCPVCQTSISDAEVEHEDQDGFFWHINYPIVGEEGRYVEIATTRPETLLGDTAVAVNPEDDRYKDLVGKMLKLPLTDREIPVVADEYVDKEFGTGCVKITPAHDPNDFEVGKRHSLPEITIMNDDATINELGGKYAGMDRYEARKAMVKDLEEQGLLVKVVPHAHSVGTHDRCHATVEPMIKPQWFVRMKEMGEAAIKTLEDGSLQFVPDRFDKIYMHWLENIRDWCISRQLWWGHRIPAYYCDKCGEVTVAGEMPKVCPKCGCDHLTQDEDTLDTWFSSALWPFSTLGWPNKTEEMEYFYPTDVLVTGYDIIFFWVIRMVFSGLEQTGKTPFHHVLIHGLIRDSQGRKMSKSLGNGIDPLEVIDKYGADALRLTLMTGNAPGNDMRFYWERVEASRNFANKVWNASRFIMMNLEKAEVPAEIDLNTLTSADKWILSKVNTLATEVTENLDKYELGIAVQKVYDFIWEEFCDWYIEMVKPRLYNDEDNTKAAALWTLKTVLGNALKLLHPYMPFITEEIFCTLHPEEESIMIASWPVEKQEWSFKEDEHAVEIIKEAVRSIRNVRTDMNVPPSKKAKVFVVSEEEEIRQVFENGRVFFATLGYASEVTIQSDKAGIAEDAVSAVTSKAVIYMPFAELVDIEKEIERLNKEAERLNKELARVNGMLKNERFLSKAPESKVAEEKAKLEKYTNMMEQVKERLAQLGR
>CP035945.1|QBE96330.1|2123782_2125951_+|Lipoteichoic-acid-synthase-2
MNKKWLKYLNLLSLPIQMVVVMLGYFVIEAISRHSVGEAYAYMTERPLVFLYNSFLIFTTTLLVYLVRRRVFMRTLLAIFWLVLGIVNGVLLANRVTPFTGPDLHLLTDAFKIANKYLSPVFFVIVIVLAVAAIIGLVFLFLKGPKYQGKMTYKLNVPLVLAGVLAFAGTTKLALEKRVLSNYFGNIAFAYEDYGYPYCLATTIFNTGISCPRDYSEAAIDKIEKSESGLPETGEKRPNIIFLQLESFFDPTLVNFLNISEDPIPTFRKLMKEYSSGYYKVPSVGAGTANTEFESITGMSLRYFGPGEYPYKSILKETTCESAPYVLKNLGYSTHAIHNNEANFYGRKNVFANLGFDSFTSEEYMSEQDDTNPNDWMRDRNLTKYIMEALESSDDPDYIYTISVQGHGDYPEEPMIDDPKITVTGGESEAVNNKWEYYCNQIYEMDQFVKELTETLSKYDEDVVLVMYGDHLPTMGLKVKDVKNRYLFQTEYVIWDNMGLEKKDANVAAYQMAAEVMDRVGIHEGNIFRFHQARRQTKNYQVDLETLQYDILYGKQYVYDGENPFARTEMHLGVKDAVLEKIEKISDGRYYITGENFTQSAYVEVNGELLDATYISPTTLLLTDVELKDGDEVDVAIRSNSSTRKVLTRTDSMIYKVPVEPLAPEVPPLEGENTEGTGEIDPNAAGIEDGAAANPIGEENSKGTESGESPIEVPNTENPVQN
>CP035945.1|QBE96331.1|2126174_2127476_+|Folylpolyglutamate-synthase
MFTYEKAAAYIEEIPKFTKKNKLEHTRKCLDMLGSPDKNRKMIHVAGTNGKGSVCAFLSTMLEEGGYRCGLFTSPHLMKINERFQINEQMVSDEKFLEAFLKVKELSDRLVEQGDYHPTYFEFLFLMGMLIFEDEDVDIVVLETGLGGRLDATNSILNPMACVITSISLDHVEYLGDTIDKIAGEKAGIIKKGVPVIFDANNETAAAVIRRRAEELGCPCHQVKAESQKLLSYTPKGIGFTFDSAVYGTTELFVPFIAKYQMMNASMAVETMGVLKGIHKIEKETLKKGLEHTRWQGRMETILPGVIVDGAHNEDGIAQFVETVRYFQEEYSITLLFATVSDKDYEDMIHRVCSGLKFANVVTTEIWGSRKQSAEELAELFRANGCGNVLAVSDSGEAFEKAYALKGDGLMFVVGSLYLAGEIKDYVRRRMND
>CP035945.1|QBE96332.1|2127468_2127618_+|hypothetical-protein
MINYEEELKKFQPCLDVDDAEGNIYKQDLTDVIDILKEMLKETNGTAKN
>CP035945.1|QBE96333.1|2127629_2129267_+|hypothetical-protein
MNCMICQAQLNTSPYCPKCGCNVTAQKKAVALSNLYYNQGLEKAQIRDLSGAITCLKRSLKMNKCNIQARNLLGLVYFETGEVVAALSEWVISKNIMPDGNVASDYINKLQSNANRLDTINTSIKKYNQCLEYCRTGNLDMAKMQLKKVLTSNPKLIKGYHLLSLIYIKEDAYEKARKQLKIAAKIDKTNTTTLRFLREVDDQTGRMTSLEPRFKAKEKNREEKDGRVIYNSGNDTIIQPPEYRERTVTNTLINLIIGLLVGASALWFLIVPAKTQKINNEANKKIVEYSDKVATQAAEIDRMQQEIDASSQSVNTANEQIAQANTKSESYDNLIKAWQAYNSGSYQNAANALESVDASLLSVDAKSMYDTIMNDIGETVKAGYKSAGITAYENQDYASAIDNLLKAQDIGEPDYDSMFYLAQSYQKSGDNANAIIWYQKIIDAFPGTSYASDAKDYMTAIGGTPTQTSAGQESGEDASTPADEGQPQEDAAGQADEGQEDGGEGSTDPGNTDDGQDDNSGEDNNGNGYSDGGDNQDGWEDTGEE
>CP035945.1|QBE96334.1|2129436_2129736_+|Anti-sigma-F-factor-antagonist
MVYVPQELDHHFATQITDEVDKELKKGNVRQLVFDFSGTTFMDSSGIGMLMGRYRLLHYSGGRVSAIHVNDRVNRIMRLSGIYKYIEISQEAVWHQKRR
>CP035945.1|QBE96335.1|2129750_2130194_+|Anti-sigma-F-factor
MENTNEMTLEMDSRSCNEGLARITVAAFATQLNPTLEEVADIKTAVSEAITNCIVHAYEKETEKIRIDCIIRGRELTVAVTDHGRGIENVERAMEPMFTTKPEQDRSGMGFAFMEAFMDMLEVESEPGKGTVVRMKKKIGTGSQVFE
>CP035945.1|QBE96336.1|2130205_2130919_+|RNA-polymerase-sigma-F-factor
MEDILALIGRAHQGDKEARDTLVEKNIGLVHSIVRRFLNRGVEAEDLFQIGSIGLLKAIDKFDTSYDVKFSTYAVPMITGEIKRFLRDDGMMKVSRSLKEICCRAYTAREELMMENGKEPEMEEIAERIAVTREELVMAMESGAQIESLQKTIYQGDGTDISLEDKIEEQRNDQEHLLNRMMLEQMLGTLDPEERKLIYMRFFQEKTQTQIAGELGISQVQVSRLEKKILSRLREKI

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Crispr_ID: CP035945_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_6

2224448-2224528

Orphan

Consensus_repeat	Method
GGCGACAGACGGGGTTAGTGAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035945_6

>merge|CP035945|6|2224448-2224528|CRISPRCasFinder
GGCGACAGACGGGGTTAGTGAGAAAGCCCACCCGAACACTTAGCGAGTCCGAGCCAATGGCGACAGACGAGGTTAGTGAGA

>CP035945|6|6|2224448-2224528|CRISPRCasFinder
GGCGACAGACGGGGTTAGTGAGA	AAGCCCACCCGAACACTTAGCGAGTCCGAGCCAAT
GGCGACAGACGAGGTTAGTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE96418.1\|2222684_2222939_+\|30S-ribosomal-protein-S17	unknown	unknown	gnl\|CDD\|235532
CP035945.1\|QBE96420.1\|2223339_2223651_+\|50S-ribosomal-protein-L24	unknown	unknown	gnl\|CDD\|234566
CP035945.1\|QBE96428.1\|2226804_2227245_+\|50S-ribosomal-protein-L15	unknown	unknown	gnl\|CDD\|235523
CP035945.1\|QBE96432.1\|2230131_2230407_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240512
CP035945.1\|QBE96419.1\|2222959_2223328_+\|50S-ribosomal-protein-L14	unknown	unknown	gnl\|CDD\|180117
CP035945.1\|QBE96427.1\|2226598_2226781_+\|50S-ribosomal-protein-L30	unknown	unknown	gnl\|CDD\|180163
CP035945.1\|QBE96425.1\|2225688_2226057_+\|50S-ribosomal-protein-L18	unknown	unknown	gnl\|CDD\|235524
CP035945.1\|QBE96422.1\|2224231_2224417_+\|30S-ribosomal-protein-S14	unknown	unknown	gnl\|CDD\|181216
CP035945.1\|QBE96424.1\|2225131_2225671_+\|50S-ribosomal-protein-L6	unknown	unknown	gnl\|CDD\|235495
CP035945.1\|QBE96417.1\|2222455_2222668_+\|50S-ribosomal-protein-L29	unknown	unknown	gnl\|CDD\|376397
CP035945.1\|QBE96421.1\|2223673_2224213_+\|50S-ribosomal-protein-L5	unknown	unknown	gnl\|CDD\|178791
CP035945.1\|QBE96415.1\|2221369_2222026_+\|30S-ribosomal-protein-S3	unknown	unknown	gnl\|CDD\|234722
CP035945.1\|QBE96426.1\|2226076_2226586_+\|30S-ribosomal-protein-S5	unknown	unknown	gnl\|CDD\|234790
CP035945.1\|QBE96413.1\|2220666_2220948_+\|30S-ribosomal-protein-S19	unknown	unknown	gnl\|CDD\|178985
CP035945.1\|QBE96430.1\|2228719_2229364_+\|Adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
CP035945.1\|QBE96416.1\|2222028_2222466_+\|50S-ribosomal-protein-L16	unknown	unknown	gnl\|CDD\|236411
CP035945.1\|QBE96429.1\|2227244_2228561_+\|Protein-translocase-subunit-SecY	unknown	unknown	gnl\|CDD\|236412
CP035945.1\|QBE96423.1\|2224618_2225020_+\|30S-ribosomal-protein-S8	unknown	unknown	gnl\|CDD\|234658
CP035945.1\|QBE96431.1\|2229367_2230123_+\|Methionine-aminopeptidase-1	unknown	unknown	gnl\|CDD\|235576
CP035945.1\|QBE96414.1\|2220971_2221358_+\|50S-ribosomal-protein-L22	unknown	unknown	gnl\|CDD\|234793

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE96418.1\|2222684_2222939_+\|30S-ribosomal-protein-S17	gnl\|CDD\|235532	PRK05610, rpsQ, 30S ribosomal protein S17; Reviewed.	6.93328e-42
CP035945.1\|QBE96420.1\|2223339_2223651_+\|50S-ribosomal-protein-L24	gnl\|CDD\|234566	PRK00004, rplX, 50S ribosomal protein L24; Reviewed.	2.89836e-42
CP035945.1\|QBE96428.1\|2226804_2227245_+\|50S-ribosomal-protein-L15	gnl\|CDD\|235523	PRK05592, rplO, 50S ribosomal protein L15; Reviewed.	1.35376e-74
CP035945.1\|QBE96432.1\|2230131_2230407_+\|hypothetical-protein	gnl\|CDD\|240512	cd06088, KOW_RPL14, KOW motif of Ribosomal Protein L14. RPL14 is a component of the large ribosomal subunit in both archaea and eukaryotes with KOW motif at its N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. Auto-antibodies to RPL14 in humans have been associated with systemic lupus erythematosus . Although RPL14 is well conserved, it is not found in all archaea, and therefore it is presumably not essential.	6.78446e-19
CP035945.1\|QBE96419.1\|2222959_2223328_+\|50S-ribosomal-protein-L14	gnl\|CDD\|180117	PRK05483, rplN, 50S ribosomal protein L14; Validated.	2.39089e-86
CP035945.1\|QBE96427.1\|2226598_2226781_+\|50S-ribosomal-protein-L30	gnl\|CDD\|180163	PRK05611, rpmD, 50S ribosomal protein L30; Reviewed.	1.22602e-24
CP035945.1\|QBE96425.1\|2225688_2226057_+\|50S-ribosomal-protein-L18	gnl\|CDD\|235524	PRK05593, rplR, 50S ribosomal protein L18; Reviewed.	2.57248e-60
CP035945.1\|QBE96422.1\|2224231_2224417_+\|30S-ribosomal-protein-S14	gnl\|CDD\|181216	PRK08061, rpsN, type Z 30S ribosomal protein S14.	4.14979e-34
CP035945.1\|QBE96424.1\|2225131_2225671_+\|50S-ribosomal-protein-L6	gnl\|CDD\|235495	PRK05498, rplF, 50S ribosomal protein L6; Validated.	2.52423e-101
CP035945.1\|QBE96417.1\|2222455_2222668_+\|50S-ribosomal-protein-L29	gnl\|CDD\|376397	pfam00831, Ribosomal_L29, Ribosomal L29 protein.	1.93316e-19
CP035945.1\|QBE96421.1\|2223673_2224213_+\|50S-ribosomal-protein-L5	gnl\|CDD\|178791	PRK00010, rplE, 50S ribosomal protein L5; Validated.	1.28205e-131
CP035945.1\|QBE96415.1\|2221369_2222026_+\|30S-ribosomal-protein-S3	gnl\|CDD\|234722	PRK00310, rpsC, 30S ribosomal protein S3; Reviewed.	6.28691e-145
CP035945.1\|QBE96426.1\|2226076_2226586_+\|30S-ribosomal-protein-S5	gnl\|CDD\|234790	PRK00550, rpsE, 30S ribosomal protein S5; Validated.	1.67023e-89
CP035945.1\|QBE96413.1\|2220666_2220948_+\|30S-ribosomal-protein-S19	gnl\|CDD\|178985	PRK00357, rpsS, 30S ribosomal protein S19; Reviewed.	2.63878e-62
CP035945.1\|QBE96430.1\|2228719_2229364_+\|Adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	4.37502e-136
CP035945.1\|QBE96416.1\|2222028_2222466_+\|50S-ribosomal-protein-L16	gnl\|CDD\|236411	PRK09203, rplP, 50S ribosomal protein L16; Reviewed.	8.79019e-97
CP035945.1\|QBE96429.1\|2227244_2228561_+\|Protein-translocase-subunit-SecY	gnl\|CDD\|236412	PRK09204, secY, preprotein translocase subunit SecY; Reviewed.	0
CP035945.1\|QBE96423.1\|2224618_2225020_+\|30S-ribosomal-protein-S8	gnl\|CDD\|234658	PRK00136, rpsH, 30S ribosomal protein S8; Validated.	9.32239e-83
CP035945.1\|QBE96431.1\|2229367_2230123_+\|Methionine-aminopeptidase-1	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	6.05786e-134
CP035945.1\|QBE96414.1\|2220971_2221358_+\|50S-ribosomal-protein-L22	gnl\|CDD\|234793	PRK00565, rplV, 50S ribosomal protein L22; Reviewed.	4.53696e-54

>CP035945.1|QBE96422.1|2224231_2224417_+|30S-ribosomal-protein-S14
MAKTAMKLKQQRKQKFSSREYNRCRICGRPHAYLRKYGICRICFRELAYKGQIPGVKKASW
>CP035945.1|QBE96421.1|2223673_2224213_+|50S-ribosomal-protein-L5
MSRLREVYKNEIVDGMVKKFGYKNIMEVPKLNKIVVNMGVGEAKENAKLLDAAVADMELITGQKAVTTKAKNSIANFKLREGMPIGCKVTLRGEKMYEFADRLINLALPRVRDFRGVNPNAFDGRGNYALGIKEQLIFPEVEYDKVDKVRGMDIIFVTTAKTDEEARELLTLFNMPFAK
>CP035945.1|QBE96420.1|2223339_2223651_+|50S-ribosomal-protein-L24
MSTFKIKKGDTVKVIAGKDKDKEGKVISVNPKKGAVLVEGANMVTKHTKPSMANQQGGIVEKEAWLDVSNVMLVHEGKATRVGFKMEGDKKVRFAKATGKVID
>CP035945.1|QBE96419.1|2222959_2223328_+|50S-ribosomal-protein-L14
MIQQESRLRVADNTGAKEILCIRVMGGSTRRYANIGDIIVATVKDATPGGVVKKGDVVKAVVVRTRKGARRKDGSYIKFDENAAVIIKDDKTPRGTRIFGPVARELREKQFMKIVSLAPEVL
>CP035945.1|QBE96418.1|2222684_2222939_+|30S-ribosomal-protein-S17
MERNLRKTRVGKVTSNKMDKTIVVAIEDHVKHPLYKKIVKRTYKLKAHDEENTCNIGDTVKVMETRPISKDKRWRLVEVVERAK
>CP035945.1|QBE96417.1|2222455_2222668_+|50S-ribosomal-protein-L29
MKIKNYVEDLKTKSAAELQEELVAAKKELFNLRFQNATNQLDNTSRIKEVRKNIARIQTLIAQNKANAAE
>CP035945.1|QBE96416.1|2222028_2222466_+|50S-ribosomal-protein-L16
MLMPKRVKRRKQFRGSMKGKALRGNKINYGEYGLVSTEPCWIKSNQIEAARVAMTRYIKRGGKVWIKIFPDKPVTAKPAETRMGSGKGALEYWVAVVKPGRVMFEIAGVPEETAREALRLAMHKLPCKCKIVSRADLEGGDNSEN
>CP035945.1|QBE96415.1|2221369_2222026_+|30S-ribosomal-protein-S3
MGQKVNPHGLRVGVIKDWDSKWYAESDFADNLVEDYNIRTFLKKKLYSAGVSKIEIERASDRVKVIIYTAKPGVVIGKGGSEIEKVKAELQNYTSKKLIVDIKEVKRPDKDAQLVAENIALQLENRISFRRAMKSTMQRTMRAGAKGIKTAVSGRLGGADMARTEFYSEGNIPLQTLRADIDYGFAEADTTYGKVGVKAWIYNGEVLPTKGTKEGSDK
>CP035945.1|QBE96414.1|2220971_2221358_+|50S-ribosomal-protein-L22
MAKGHRSQIKRARNANKDTRPSAKISYARMSVQKACYVLDVIRGKDVQTALGILTYNPRYASSVIKKLLESAIANAENNNGMNPENLYIAECYANKAPTMKRIKPRAQGRAYRIEKRNCHVTVVLDER
>CP035945.1|QBE96413.1|2220666_2220948_+|30S-ribosomal-protein-S19
MARSLKKGPFADESLLKKVDALNAAGNKTVIKTWSRRSTIFPSFVGHTFAVHDGRKHVPVYVTEDMVGHKLGEFVATRTYRGHGKDEKKSGVR
>CP035945.1|QBE96423.1|2224618_2225020_+|30S-ribosomal-protein-S8
MTMSDPIADMLTRIRNANTAKHDTVDVPASKMKLAIADILVKEGYIAKYDVLEDGAFKTIRITLKYGADKSEKIITGLKRISKPGLRVYAGSQEIPRVLGGLGIAILSTNQGVITDKEARKLHVGGEVLAFVW
>CP035945.1|QBE96424.1|2225131_2225671_+|50S-ribosomal-protein-L6
MSRIGRQPVAVLAGVEVKIAENNFVTVKGAKGTLEKALPTEMSIKLEDGQVVVTRPNDLKKMKSLHGLTRTLIQNMVIGVSQGYEKTLEVNGVGYKAAKQGKKLVLSLGYSHPVEMEDPEGLESSVDGNKIVVKGIDKEKVGQYAAEIRDKRRPEPYKGKGIKYADEVIRRKVGKTGKK
>CP035945.1|QBE96425.1|2225688_2226057_+|50S-ribosomal-protein-L18
MVSKVSRAKVRAKKHRRLRNHLSGTATTPRLAVFRSNNHMYAQIIDDTVGKTLVSASTTQKEVKAELEKTNNVDAAAYLGTVIGKKAIEAGIKEVVFDRGGFIYHGKVQALADAAREAGLEF
>CP035945.1|QBE96426.1|2226076_2226586_+|30S-ribosomal-protein-S5
MRRSIIDASQLELEEKVVSIKRVTKVVKGGRNFRFTALVVVGDGNGHVGAGLGKAAEIPEAIRKGKEDAMKKLVTVARDDNGSITHDFIGKFGSAEMLLKKAPEGTGVIAGGPARAVIELAGIKNIRTKCMGSRNKQNVVLATIAGLSQLKTPEEVAKLRGKSVDEIFA
>CP035945.1|QBE96427.1|2226598_2226781_+|50S-ribosomal-protein-L30
MADKLRITLVKSTIGAVPKNRKTVEALGLRKLNKTVEMPDNAAVRGMVRQVRHLVKVEEI
>CP035945.1|QBE96428.1|2226804_2227245_+|50S-ribosomal-protein-L15
MDLSNLKPAEGSRQSDNFRRGRGHGSGNGKTAGKGHKGQKARSGAKRPGFEGGQMPLYRRLPKRGFKCRNSKDIVAINVSELNRFEDGAEVTPAALLASGAISRLGDGVKILGNGEITKKINLKVNAVSETAKTKIEAAGGTVEVI
>CP035945.1|QBE96429.1|2227244_2228561_+|Protein-translocase-subunit-SecY
MLETLRNAFKIKDVRRRIYYVLLMLVVVRIGSQLPIPGVDRDFFKNLFASQSNDAFNFFNAFTGGSFEQMSIFALSITPYITSSIIIQLLTIAIPKLEEMQRDGEEGRKKMTAITRYLTVGLALFQSVAMVIGFGNRGWLTEMNFTSIVVAVVTLTGGSAMLMWIGEQITEKGVGNGISIVLMINIVSRIPSDLASLFEKFVKGKTIARGGLAAIIIMAIIIVVVVLVLILNGGERKIPVQYSKKMVGRKMMGGQSSAIPLKVNTAGVIPIIFASSLMSFPVVIASFLGKGGGTGIGSKILKGLTSSNWFNPNEPVYSIGLVVYIVLVIFFAYFYTSITFNPMEVADNMKKQGGFIPGIRPGKPTQEYLEKILSYIIFIGATGLVIVAVIPFFFNGVFGANVSFGGTSIIIVVGVVLETIKQVESRMLVRNYKGFLSE
>CP035945.1|QBE96430.1|2228719_2229364_+|Adenylate-kinase
MKIIMLGAPGAGKGTQAKKIADKYQVPHISTGDIFRANIKNGTELGKKAKTFMDQGLLVPDELVVDLVVDRVAQDDCENGYVLDGFPRTIPQAESLDAALAKMGQKVDYAIDVDVPDENIVNRMSGRRACVGCGATYHIKYNPPKKEDVCDICGEKLILRDDDKPETVLKRLTVYHDQTQPLIDYYTKSGVLKQVDGTVDMEDVFQAIVKILGA
>CP035945.1|QBE96431.1|2229367_2230123_+|Methionine-aminopeptidase-1
MSVSIKTANEIELMREAGKLLEKVHDELKDFIRPGISTLDIDQYGEKLIRQMGCIPNFLNYNGYPASICVSVNDEVVHGIPRKDHILQDGDIVSLDAGLIYKGYHSDAARTHAVGEIAPEAQKLIDVTRQSFFEGIKYARAGQHLYEISAAIGAYAEKFGYGVVRDLVGHGIGTSLHEDPQIPNFRQKRRGLRLQAGMTLAIEPMINEGRADVVWLDDDWTVVTEDGFLSAHYENTILITDGEPEILTLSE
>CP035945.1|QBE96432.1|2230131_2230407_+|hypothetical-protein
MSEVRAGMAALSMAGHDTGRYYIIVRAVDGYVYLADGTLRTCEHPKKKKLRHVQINRRISPVIEGILSEGGELKNETIKRVIKEYRSKQEV

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Crispr_ID: CP035945_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_7

2639107-2639213

Orphan

Consensus_repeat	Method
GAGAATCTAATACCAGAATGGAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP035945_7

>merge|CP035945|7|2639107-2639213|CRISPRCasFinder
GAGAATCTAATACCAGAATGGAATACTCCGGCAGAGTATTATAATACTGGAAATAGGATGTCCAAGCAAAGAATGCAAAGGCAGAGAATCTGATACCAGAATGGAAT

>CP035945|7|7|2639107-2639213|CRISPRCasFinder
GAGAATCTAATACCAGAATGGAAT	ACTCCGGCAGAGTATTATAATACTGGAAATAGGATGTCCAAGCAAAGAATGCAAAGGCA
GAGAATCTGATACCAGAATGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE96780.1\|2646102_2647452_+\|Multidrug-resistance-protein-MdtK	unknown	unknown	gnl\|CDD\|240539
CP035945.1\|QBE96783.1\|2649396_2650077_+\|ABC-transporter-ATP-binding-protein-YxdL	unknown	unknown	gnl\|CDD\|224059
CP035945.1\|QBE96772.1\|2633083_2633578_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379082
CP035945.1\|QBE96766.1\|2626941_2627799_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379425
CP035945.1\|QBE96785.1\|2652620_2653913_+\|Cyclodextrin-binding-protein	unknown	unknown	gnl\|CDD\|270303
CP035945.1\|QBE96784.1\|2650073_2652461_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226957
CP035945.1\|QBE96777.1\|2641124_2644451_+\|Sensory/regulatory-protein-RpfC	unknown	unknown	gnl\|CDD\|274362
CP035945.1\|QBE96778.1\|2644462_2645359_-\|Melibiose-operon-regulatory-protein	unknown	unknown	gnl\|CDD\|197666
CP035945.1\|QBE96775.1\|2636777_2638154_-\|putative-symporter-YjmB	unknown	unknown	gnl\|CDD\|379134
CP035945.1\|QBE96779.1\|2645474_2646110_+\|Galactoside-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP035945.1\|QBE96776.1\|2639456_2640950_+\|ATP-dependent-RNA-helicase-DbpA	unknown	unknown	gnl\|CDD\|236977
CP035945.1\|QBE96770.1\|2631568_2632378_+\|Multidrug-efflux-transporter-1-regulator	unknown	unknown	gnl\|CDD\|133409
CP035945.1\|QBE96773.1\|2634029_2635445_-\|Multidrug-export-protein-MepA	unknown	unknown	gnl\|CDD\|240548
CP035945.1\|QBE96767.1\|2628345_2628996_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379326
CP035945.1\|QBE96781.1\|2647584_2648268_+\|Transcriptional-regulatory-protein-AfsQ1	unknown	unknown	gnl\|CDD\|223816
CP035945.1\|QBE96774.1\|2635621_2636698_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239425
CP035945.1\|QBE96769.1\|2630343_2631441_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274334
CP035945.1\|QBE96771.1\|2632407_2633028_+\|Intracellular-iron-chaperone-frataxin	unknown	unknown	gnl\|CDD\|227933
CP035945.1\|QBE96768.1\|2629012_2630347_-\|Multidrug-export-protein-MepA	unknown	unknown	gnl\|CDD\|240548
CP035945.1\|QBE96782.1\|2648269_2649286_+\|Alkaline-phosphatase-synthesis-sensor-protein-PhoR	unknown	unknown	gnl\|CDD\|223715

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE96780.1\|2646102_2647452_+\|Multidrug-resistance-protein-MdtK	gnl\|CDD\|240539	cd13134, MATE_like_8, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.565e-113
CP035945.1\|QBE96783.1\|2649396_2650077_+\|ABC-transporter-ATP-binding-protein-YxdL	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.16157e-107
CP035945.1\|QBE96772.1\|2633083_2633578_+\|hypothetical-protein	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	1.36309e-14
CP035945.1\|QBE96766.1\|2626941_2627799_+\|hypothetical-protein	gnl\|CDD\|379425	pfam14022, DUF4238, Protein of unknown function (DUF4238). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 274 and 374 amino acids in length.	1.05392e-23
CP035945.1\|QBE96785.1\|2652620_2653913_+\|Cyclodextrin-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.36972e-90
CP035945.1\|QBE96784.1\|2650073_2652461_+\|hypothetical-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	7.29571e-15
CP035945.1\|QBE96777.1\|2641124_2644451_+\|Sensory/regulatory-protein-RpfC	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	2.69481e-65
CP035945.1\|QBE96778.1\|2644462_2645359_-\|Melibiose-operon-regulatory-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	3.85629e-25
CP035945.1\|QBE96775.1\|2636777_2638154_-\|putative-symporter-YjmB	gnl\|CDD\|379134	pfam13347, MFS_2, MFS/sugar transport protein. This family is part of the major facilitator superfamily of membrane transport proteins.	7.89121e-26
CP035945.1\|QBE96779.1\|2645474_2646110_+\|Galactoside-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	6.3508e-96
CP035945.1\|QBE96776.1\|2639456_2640950_+\|ATP-dependent-RNA-helicase-DbpA	gnl\|CDD\|236977	PRK11776, PRK11776, ATP-dependent RNA helicase DbpA; Provisional.	2.09015e-130
CP035945.1\|QBE96770.1\|2631568_2632378_+\|Multidrug-efflux-transporter-1-regulator	gnl\|CDD\|133409	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BltR (BmrR-like transporter) of Bacillus subtilis, and related proteins; N-terminal domain. Blt, like Bmr, is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. These regulators are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	8.83864e-25
CP035945.1\|QBE96773.1\|2634029_2635445_-\|Multidrug-export-protein-MepA	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	2.30549e-133
CP035945.1\|QBE96767.1\|2628345_2628996_-\|hypothetical-protein	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.20402e-08
CP035945.1\|QBE96781.1\|2647584_2648268_+\|Transcriptional-regulatory-protein-AfsQ1	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.02718e-68
CP035945.1\|QBE96774.1\|2635621_2636698_-\|hypothetical-protein	gnl\|CDD\|239425	cd03309, CmuC_like, CmuC_like. Proteins similar to the putative corrinoid methyltransferase CmuC. Its function has been inferred from sequence similarity to the methyltransferases CmuA and MtaA. Mutants of Methylobacterium sp. disrupted in cmuC and purU appear deficient in some step of chloromethane metabolism.	2.15037e-40
CP035945.1\|QBE96769.1\|2630343_2631441_-\|hypothetical-protein	gnl\|CDD\|274334	TIGR02872, UPF0118_membrane_protein_YtvI, sporulation integral membrane protein YtvI. Three lines of evidence show this protein to be involved in sporulation. First, it is under control of a sporulation-specific sigma factor, sigma-E. Second, mutation leads to a sporulation defect. Third, it if found in exactly those genomes whose bacteria are capable of sporulation, except for being absent in Clostridium acetobutylicum ATCC824. This protein has extensive hydrophobic regions and is likely an integral membrane protein. [Cellular processes, Sporulation and germination].	4.25662e-50
CP035945.1\|QBE96771.1\|2632407_2633028_+\|Intracellular-iron-chaperone-frataxin	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	8.97842e-28
CP035945.1\|QBE96768.1\|2629012_2630347_-\|Multidrug-export-protein-MepA	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	2.40043e-93
CP035945.1\|QBE96782.1\|2648269_2649286_+\|Alkaline-phosphatase-synthesis-sensor-protein-PhoR	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.81203e-54

>CP035945.1|QBE96775.1|2636777_2638154_-|putative-symporter-YjmB
MEITSSKKEIWTMGSYSLLTLAIMVGFMYLNTFATEVLVIPAGTLALALGVAKLLDFCFSLFAGAIIEKVKIGKTGKNQSWLYLGRWILAVSIMAEVCNTSAAPLIVRVAVLSVSYTVLNCLMNILQTAYYGVLAAVAGPNMANRNAMTINMTRQSTVITIICSFIPTFVTVLPFGNWNYFIVAFVFMLPMPFALGAIAKCADGKDVPVGATGSVNQVGIGDMFGTLLKNPQMLILFLVFTILYIAQFTYQANYTYYFIYVVGDFTKMTLATLINAFVGFLAAMVMPKLGAKLGKKMSCVFGFAMMSVALILVSFFGAPNGVPNLTAYIIIMSLLMAGTYTWMPYMVVLFLDAGEYFLYKTGKDTRAIAAGLASPPMKIGMTVGNTLGLALLSAIGFVSGGAFEISVTWITNFMRVTFMLPGLIYLAAAIIMLLFYKISDKDAAMYAQANAEKMQQSK
>CP035945.1|QBE96774.1|2635621_2636698_-|hypothetical-protein
MSKIPFNENEMNIAYTVPNLFDPTVPESPAWTYPQSEKDAIQELYAGTPTWCPSGLETGLFAPSVIPDNIARGFVIEGIPYDMAKYGGPDMFGVEWEYVPVAGGSMVRPGAPLLEDVNDWRKILKFPNIDEWDWDASGRENYKFLQNGKANMLWFLNGCWYERLVSFMDFEGAVVALIDDEQKDALKELFAETTELYCRLVDRCAETYGDGISGFTVHDDWGSQRAPFFSPAVGEEMIVPYMRQLTDHIKSKGLIADLHSCGSLEMQLPNFIKAGWQSWCPMPMNPTQKMYEEYGDKILLHVEPDLPEGASEEEQEKAGEEFVRNYFKPGKYCFPNTTYFPKKVTPAFRKGMYRASRQ
>CP035945.1|QBE96773.1|2634029_2635445_-|Multidrug-export-protein-MepA
MSDKNPTPAIPPVENNIMGTAPIPKLLAKFAIPSVISMLVNSIYNLVDQIFIGQGVGYLGNAATNVVFPFVTIAMAISLMVSVGTAANVGLHLGGKEQDSADLTLGNGLTLALSSGIILCIFGEIFMVPLLRLFGATDTVLPYAVDYGRIYLLGTMFTSVGIMINDEIRADGNPGYAMRSMLIGAVLNCVLDPLFIFVFHWGVKGAALATIIGQFGTLVFSLLYLKKFRTLTMKKENMRLRFSIVKDILTLGLSSFLTQCAALVMQIIMNQQTIKYGALSQYGADIPLTVFGIVNKVNGLMMSIIMGISVGAQPLFSYNFGAKLFTRVKKLAKTCLIVCVTIGFLGMLCLQLFPQQIISIFGQENDLYNEFAVMCLKNMTIFIFVMGVQMVASVYFQAVGKAMGATVLSLSRQVLFMIPCMLILPYFFGIIGLMWSFPVSDVFSVAMAAVMLTVEMRKLNQLIRVPVVQEA
>CP035945.1|QBE96772.1|2633083_2633578_+|hypothetical-protein
MKKLYMIGGTMGVGKTSACQILKQKLDNSVFLDGDWCWDMHPFQVTQETKKMVLENIAFLLNNFIQCSAYENIIFCWVMHEQDIIDDILSRLDTAGCQIRSISFVCSQEALRARLQKDVNMGIRTADVIPRSLERVSMYEKLDSVKIDISGLSPEQAAEMVIGL
>CP035945.1|QBE96771.1|2632407_2633028_+|Intracellular-iron-chaperone-frataxin
MKKILEFDAVLIKNPGMDAAYVEVPFDIKTIFGKSRLPVHATFDGEPYDGQVVKMGTPCHIIGVRKDIRTKIGKRPGDIVHVTLEEREKPKLAFSSVDEYIASYSGDVRQRMETLRQIILECSPDITEKISWGMATFVLNGNLVHFSGEKRHLGFHPSPSAIEAFKDSFAEYKYSKGTLQLPYDKPMPYELLRQMIMFGVQEQMKK
>CP035945.1|QBE96770.1|2631568_2632378_+|Multidrug-efflux-transporter-1-regulator
MGKLLRIGQVCKLYGISLDTLRYYDKMGLLKPLVTEPSGYRYYSFEQLDILEMILAGRSLDIPLENLQKRLVSGKIEDYMILVEEQQAAIVERKKALEQLENHSRQMADLLMEITLHQNDHNLRNIQYETLDKEICQISVAAFPPTGFDGNDAGSFLQMEQWSFYLSDSKGIVAEPPQEAGISVQNEECARKMVTNSSCTKIVKVTGTYGKIKFWGKNKELHTYLNKICRSFNLWNAQMLVKYIFALAHEDLDNEYFVEIYFPIQGSGR
>CP035945.1|QBE96769.1|2630343_2631441_-|hypothetical-protein
MCVEKMKEFIIRILFWALVGGLAFLIVGYILPVLKPFIAAFVIAVILNPVIRRFIKNGRFRRKWVSVMVLVLFYMIMLLFIAGAGVDFADFIKTSVAKFPELYDHTVLPALESTAGGVEAAAKHLSPDFQRMTGYIGESVSDAMSGFVRKASSAMVELVTGTAAKTPQMLMNFIITIIASFFCVIDYEKIIAFMKNHLPSKITQVSIQIKKRGFSVFLQFGKAYLFLMSLTFAELVVGLSLLKIEDSILLAGIIAFVDILPVFGVGTVLLPWIAVSFLIGSVPLGVGLLILYIIITIVRQVLEPRVVGQQIGLHPLITMICMFVGTYFFGIIGLFGFPVLATILAQSKRNDGFFFNGKNSKGAQI
>CP035945.1|QBE96768.1|2629012_2630347_-|Multidrug-export-protein-MepA
MSEHLTIYQKPVTFWNMLKFTFPTMVMALIQVLYTTVDGIFVARFVGTDAMAALTLLSPYFSLLFAISTMLSSGGSAIVMRKMGERKENEAKQDFTALILLNFFLGILFTVIGILFSEPLTNVFGASPQVTLYCKEYLFYYVLFAIPTLLMSNLQVYVVAANSPVLAFGVSLSAGLVNVGLDYLFVAVAGWGVKGTAVATGFSSLIPTIICIVYFMKKSRLLHFVKPLFRIRTLIDSATNGMSEMATTLVSGITALFMNGALLRYSGENGVAAYTIIYYVFSAMTALYIGYIYGAAPVISYNYGQRDTIKLKKLTKVNLIFIALVSGISALSTWAFGGNLIGIFAGMGTAVYEIAAHGNFIFTFALLFNGFNTYASGMFTALSNGIVSGVIAFCRTFLFSLGAILLLPEILQINGVWLATPAAEFLGIIVSLICFFRYKKRYGY
>CP035945.1|QBE96767.1|2628345_2628996_-|hypothetical-protein
MGKITYREICREDHNSIKKLIDEVWNLNQFCGTTQGLEDSLNIYLQSSLLDISYGKVAILDGEVVGILLGKNECQKILFKRRTILWRLVKSCVSLLLHSSRLMRLQLRNALKISKAEQEMIDAQKKIFTGHIELLIVGKEAQGLGIGKALVDDFISYAIHGNENAVYVQTDTLCNYGFYEHQGFEQLDSTKIALNDDDQITLFLYQYKQGENLQKL
>CP035945.1|QBE96766.1|2626941_2627799_+|hypothetical-protein
MNNIPRRHHIVPQCYLKYFVNDSGKIKVFDKLKICEYYASPKDLAVRRDFYRDYLRSNELIWEEFYSMNVENSLPETFEKIINKSTKLKSTEKILVDEVKNKMSKIIITQLFRSEKWRRHSYNSFSPKIPLILKNTKEKLDLLKERTGETYISKTGLEAFAKNQYLELANHEIILNISCQILIDRNWILIRSKLYDKKIFTSDNPVVLYNEKLKSYKIEDNYITDSNNFIFFPISTQLFLMILPSNNTKLVDFGEYADCIIDGTKEIIDFQNFGQMIQASRQVFI
>CP035945.1|QBE96776.1|2639456_2640950_+|ATP-dependent-RNA-helicase-DbpA
MDKYRPASEIKKGKIVMINKFNEYALSEEILEALNGLGYREPTGIQREVLLPMLAGKNVVVKAPTGSGKTAAFGIPICESVRWEENAPQALVLEPTRELAVQVSEELFHIGRKKRLKVPAVFGGFPIDKQIQTLRQKSHIVTGTPGRVADHLGRESLKLDRLKWLVIDEADLMLDMGFIEQVRTILSLVPENCRISLFSATLKPEIRELADEFIPHITYVLQEPTDEQTAAITEKVYFTDQENKYDAFLHVLMDENPQSCMIFCGTREMTNVLFQKMRRRRIFCGMLHGEMEQRERLKTVDAFRRGCFRFLIATDVAARGVDFEQITHVVNYDFPTGKETYVHRIGRTGRNGKCGTAVSLVTEEDKKMLKQVEEFVGQNLPCMELPVPDEEKEKAFWKSQRIKTEAKPKKGAALNEGITRLSIGGGRKSKMRAGDIVGAVCSLDGVEASDIGIVDIRDSLSYVEVLNFKGEQVIKCLQAKPIKGKIRKVRKTKRLRD
>CP035945.1|QBE96777.1|2641124_2644451_+|Sensory/regulatory-protein-RpfC
MKLRSKMVYEQRIEEVKKLAGRIMHKHYCEHDTEWITSYFAPQFSWLGAGEEECMSGREACTEQFIKYKEFIPDCTIREEEYDVICPEEDMYVVMGRMWIATDQSVEMYLKVHQRVTFVFQDTEEGLKCCHIHCSNPYQEMMDGEHFPDKIGRQSYDYVQERLAELEEEIKQRNRQLEVIMSSIAGGLKISNDDDTYSFAFVSKEAAALFGYTVEEFMKVTGGTAVGTVYPPDLPKALADCDEAFRDGNLTYSTRYRVRCRDGSLKWVIDSGKKAQDADGNWMVNSLYLDITRSEEAAQKLREQTQLLTSIYDTVPCGIIRFMQCRDEQYRLISLNKAALSLMGYDSLEEGMNDWHEGTMGAVLPEDKSIIQETYHQMTGVGDCQEIEYRVRWKDGSIHWMNATNMVVDTTPDGEKILQRTVVDITQRKALQERLDREQEMYRLAMEAGSSVMFEYLIDEDVFISFEPRKGKGVLRHELRDYSKRLLKDQIVHPDDVATVIDNICKGRTEVFEVRCSVPDGVKGQYFWYRANSRLMMDNGKPSRVVGALHDIHSMKSKLSESSERLYMSQSALQAINDVYVSIFYVDLQNDSYYAVRLPEADKGGSLSRTGRYSTKLCSYILEDIDGGDLNKMADICSRERLLRELAGKNEHLEVEFRHKHSVLWLRMEIHLVSAENDRPKTVIIAFRNISEEKQKELEYYEEEKKAKHALEEAYDSVNRANQAKSDFLSRMSHDIRTPMNAILGMTAIAEKTLGDEKKTADCLKKIQLSGAHLLELINEVLDMSKIESGNVSLSEDAFCLRDVLSEVSQIIRPDIDGKRHHLSVNIKDVEHPSVYGDPVRIKQILLNLLSNAVKYTHESGHITVTLEEKLSSESGVGCFEFVVADDGIGMSEEFKKKLFLPFERAEDSRVSRIQGTGLGLAITRNLVQMMNGTIEVESRLNQGTRFIVTIYLKLAQETEVGEEQESRDMPVAETVLPPGACVLLAEDNLLNQEIVKELLALSGINSVCTSNGQEVVERFLADPPGTYALILMDIQMPVLDGYGASRAIRRLGETGERPDAAHIPIIALTANAFADDAYQAKQAGMNEHVAKPLEMGRLLEIMKKWTS
>CP035945.1|QBE96778.1|2644462_2645359_-|Melibiose-operon-regulatory-protein
MNGVSILKDASEIVHYNNPNIPLYLKDRWLSSYTNMEALCHWHEDIEYMKALKGHMIYYVNGEKLTIHENDALIVNTRQMHYGFSDDKTDCYFACIVFRLHLLCTNPELTEKYIHPIAEHPDLPYIRLHAANPAEAAIIQLFDAACEDCRKGSAGYELMVISRLTAAWVELYRLLSPGLLSYSSVIEDDLSIQRNMISYIYQNYAQKLSLNDIAAAGSICRSKCCRIFKKYLNKTPIDFLNAYRLEVSMRLLTDTAMSITEIALSCGFQSPSYYAELFQHHKGCTPSHYRTRQAKGYL
>CP035945.1|QBE96779.1|2645474_2646110_+|Galactoside-O-acetyltransferase
MDNITRRDAGLPYISDDAVFEQQKITRRLLREFNATDPSDFETLGRLAGRIVDGAEENVSVMPPFYCDYGFHIQVGKGFFANYNCTILDVAKVTIGENVLFAPNVSIYTAGHPVHPVSRQSGYEYGIPVSIGNNVWIGGNVVITPGVTIGDNVVIGAGSVVTKDIPANVVAAGNPCRVIREITDADKKYYYKDREFDPESWAEIEAMENGE
>CP035945.1|QBE96780.1|2646102_2647452_+|Multidrug-resistance-protein-MdtK
MSDRGIFYKKLFTLVLPIAFQNFMTAAVSASDAIMLGVISQEALSAVSLAGQIQFVLSLFLAALTIGTTILAAQYWGKGDKVSVEKILAIALRFSSAISLIFFLGTLFIPETLMGIFTPDAELTAQGAEYLRIVGVSYLLMGISQIYLCIMKNSGNTLKSTVIGSVSMVTNIVLNAVFIFGVWKIPAMGIAGAALATVLSRVLELAWAFAESLRHGRVKLHVRYLFHSDGDLKRDFFHYTLPVLGNELIWGCGFTMYSVIMGHLGSDAVAANSIANIVKNLIACLCLGLASGGGIIVGNELGKGNLSGAKDYGDRLCRLSILMGALSGLLLLGLSPLILGFSNLSPTAHGYLKGMLFMCTYYLIGKSVNSTVIAGIFCAGGDSRFGLFCDAVTMWAVTVPLGLLTAFYFKIPILAVYFIINLDEIIKLPAVYRHYKKYNWVRDITRSSL
>CP035945.1|QBE96781.1|2647584_2648268_+|Transcriptional-regulatory-protein-AfsQ1
MSRVLIIEDDEILNAGLCFHLQRKEIEVEPAYSLAEAEEYLKGHEPDLILLDVNLPDGNGFDFARKVLIKQSAAFVFLTAHNLDDDVIQGLQLGADDYITKPFSIRVVVEKIQTILRRCARADKDSKIYVCKNLMVDFERRTVSKDGQMLTLTPTEFNLLELFCRNPNRILSKELLLEKVWDDRGNYVNDHALTLNISRLRGKLEDGENNCIKTVYGMGYEWVGGSR
>CP035945.1|QBE96782.1|2648269_2649286_+|Alkaline-phosphatase-synthesis-sensor-protein-PhoR
MKKIIRFFLTAFHFLAVCGGSIFLFVQPVSFSAKVILCAVLWGLWAAGMGSFLYFRNQYVKYSGDVCRYAQQIMEGNPCSEVQNQETLTSKMVMELKKTGEILEYKASAAEKEKAETQQLVSDITHQLKTPVTNIKMYGDTLCEEELSGEEVRQFVQIIVQQIGKLEFLIDALSKMSRLESRMMHMHPDHCKVNRTVSQAIDTVASRAKEKGIELQVNVRETLEVCHDSKWTAEALGNILDNAVKYTESGGKIIVSARNLEMYVVISVSDTGIGIDSGHYNQIFQRFYREAKAAKTEGLGIGLYLARQIITLQGGYIKVRSKAGYGTEFEVFLPRRAA
>CP035945.1|QBE96783.1|2649396_2650077_+|ABC-transporter-ATP-binding-protein-YxdL
MNILQTRNLTKYYGKEPLLVKALDGINMEIEQGSFTAIVGRSGSGKSTLLHMLGGLDCPTGGSVMVDGQELSGLDSNELTIFRRRKIGFVFQNFNLMPNLNIYDNIVLPVELDGRSADDKYLKEIVTVLGLEDKLKRKPGKLSGGQQQRAAIARALVTKPAIILADEPTGNLDSQTSQEVLGLFQAASRRFHQTLVMITHNEEIAQVADRTIRIEDGKIVESGWSS
>CP035945.1|QBE96784.1|2650073_2652461_+|hypothetical-protein
MNIDKNNNRRVVWRTAKSNLLGNRLYSFFTVLTIILAVSLISGLAMVQKSAETKKQKILDTMQHVMYMNITEQQMQGLSEDEQTEMMVPYKEGSEVKEDGVKLYPFYIESHSSGIVTYTPAEGKVPELENEIAVDRQLLKALGKEEKTGTELELSFADGERESFVVCGILERDQELSRYPVYVSKAYADNSRALRDIPYTALVKIVDAGDMQISEFSGVVNNLAVKYEIDRNQVNINGNFEYSLQKTSAVLLIGVVGLIILFAAVVVIYSIFYLSVTGRIHQIGQLRTIGMTKKQINRMIFSEGLMLSGIGIPAGILIGIVSAYFIRPGGFTGAGLFLTVCMSAAFGVLTVLFSVSKPAKMAGNISPVEAVRYTGDEKSREEKDRPHRKLTARTMAKSVWNNNGKRGVLTTVSLAIGGILFMTGAAYMAAWDAEEYSRAGDFEDWEYIVDYAYDAHGNTQRYGITEWQMEGTLSEELKQKLENIPNVKRVKKEINTSAIIRDGSRELMENIYPVTEENREELDALLDAGSTDRLDQNSVIIVNTRLIESIFQISLDMEKEVELEWYNGTDRERTVKIVGVKERADDDRNLEDGIYISGKVMEEMWPEMNKTSAFYVTAEEYGNNAEAVEEDILNILDDYKNLRLQTLREKKIDDAAQTKALNTQVYGLTIFIIIFSIFNMINTSISSITARRREFAMLESIGMERRQIVKMLCIENIYLAVPNLIITLTAGGLAGFGIVWALRKYAGAAYMHFQFPLAEYGIYALCMLFVPMLITYICLRLQNRDSLVTRINYTE
>CP035945.1|QBE96785.1|2652620_2653913_+|Cyclodextrin-binding-protein
MRLKRMSAILLASAAAAVLAACGQNADGQEKESSRSEKKSDGVLSVMTWDDNQAKGLQKILDDFTKETGIEAETGVVKWDEYWTMLDAGARGGTLPDVFWMHSNEAERYMTNGLLLDLTDKIESSDRIDLANYPEDIVKLYNNNNKQYAVPKDVDTIALWYNKKMFDEAGVEYPTAEWTWNDVFEAAKKLTKEDGSQYGLAMRNDNNQAGYYNMIYDNGGYIISEDKKKSGWDDPKTIQAMEMLESWIQAGVMPTLETMSENGEDVLFQSGKIAMTFQGSWMLAYFKENEYTAENCDCVELPMNAETGKRMSVYNGLGWAAAANGEHTEDAWKLIEYLGSKEAQIKQAELGITMSAYKDTSDAWANSADFNLKAYLNMMDDMVIRPYSKTTVTWENKANEILKEVYAGDKPMADACREIAEFMNQSLAEE

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Crispr_ID: CP035945_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_9

3566115-3566741

Orphan

Consensus_repeat	Method
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	PILER-CR
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	CRISPRCasFinder
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	CRT

9 spacers

The CRISPR arrays of CP035945_9

>merge|CP035945|9|3566115-3566741|PILER-CR,CRISPRCasFinder,CRT
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAATTTTTTCAAAGTTTGGCTGTTCCATGGTTTAATAAGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATCAGAGCTATCACGGTATCCTGGAAGCTGAAAGAGGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATAGCATATAACTCCCCTGTTCGCAGGTCCTTGCCGGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATAATCGGTAGTGGGAGTGATAAAAACAGCAAAGTCGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATACGGATGAATTAAACCTACGAAGCCTGGGATTTACGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATAGTTCCACGTCTACCTGGACGCTGTGCCCCTGATGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATTCGTTGTATAGTAATATCCAGCCGCTATCAATGGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATGCCTTAAAATTGCAGTACCATTTAAAGTGTTTGAAGTCTCCAGCTTTGCGCTGGAGTGGATTGAAATTTTCGTCATTTCATGCATCATAAACCTTAGTCTCGTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT

>CP035945|9|2|3566115-3566741|PILER-CR
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TTTTTCAAAGTTTGGCTGTTCCATGGTTTAATAA
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	CAGAGCTATCACGGTATCCTGGAAGCTGAAAGAG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AGCATATAACTCCCCTGTTCGCAGGTCCTTGCCG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AATCGGTAGTGGGAGTGATAAAAACAGCAAAGTC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	ACGGATGAATTAAACCTACGAAGCCTGGGATTTAC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AGTTCCACGTCTACCTGGACGCTGTGCCCCTGAT
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TCGTTGTATAGTAATATCCAGCCGCTATCAATG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	GCCTTAAAATTGCAGTACCATTTAAAGTGTTTGAA
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TTTCGTCATTTCATGCATCATAAACCTTAGTCTC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT

>CP035945|9|9|3566115-3566741|CRISPRCasFinder
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TTTTTCAAAGTTTGGCTGTTCCATGGTTTAATAA
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	CAGAGCTATCACGGTATCCTGGAAGCTGAAAGAG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AGCATATAACTCCCCTGTTCGCAGGTCCTTGCCG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AATCGGTAGTGGGAGTGATAAAAACAGCAAAGTC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	ACGGATGAATTAAACCTACGAAGCCTGGGATTTAC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AGTTCCACGTCTACCTGGACGCTGTGCCCCTGAT
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TCGTTGTATAGTAATATCCAGCCGCTATCAATG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	GCCTTAAAATTGCAGTACCATTTAAAGTGTTTGAA
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TTTCGTCATTTCATGCATCATAAACCTTAGTCTC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT

>CP035945|9|2|3566115-3566741|CRT
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TTTTTCAAAGTTTGGCTGTTCCATGGTTTAATAA
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	CAGAGCTATCACGGTATCCTGGAAGCTGAAAGAG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AGCATATAACTCCCCTGTTCGCAGGTCCTTGCCG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AATCGGTAGTGGGAGTGATAAAAACAGCAAAGTC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	ACGGATGAATTAAACCTACGAAGCCTGGGATTTAC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	AGTTCCACGTCTACCTGGACGCTGTGCCCCTGAT
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TCGTTGTATAGTAATATCCAGCCGCTATCAATG
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	GCCTTAAAATTGCAGTACCATTTAAAGTGTTTGAA
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT	TTTCGTCATTTCATGCATCATAAACCTTAGTCTC
GTCTCCAGCTTTGCGCTGGAGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE97587.1\|3563088_3563841_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366181
CP035945.1\|QBE97597.1\|3574835_3575672_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE97590.1\|3566844_3567441_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224584
CP035945.1\|QBE97586.1\|3562521_3563073_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379228
CP035945.1\|QBE97581.1\|3558321_3558984_-\|Transcriptional-regulator-DauR	unknown	unknown	gnl\|CDD\|225512
CP035945.1\|QBE97599.1\|3576959_3577526_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366181
CP035945.1\|QBE97588.1\|3563854_3564280_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE97589.1\|3564465_3565737_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379252
CP035945.1\|QBE97594.1\|3571075_3571777_+\|putative-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
CP035945.1\|QBE97598.1\|3575680_3576979_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225121
CP035945.1\|QBE97595.1\|3571770_3574029_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226957
CP035945.1\|QBE97584.1\|3560554_3561985_+\|Malate-2H(+)/Na(+)-lactate-antiporter	unknown	unknown	gnl\|CDD\|224671
CP035945.1\|QBE97593.1\|3570485_3571079_+\|HTH-type-transcriptional-repressor-AcnR	unknown	unknown	gnl\|CDD\|224228
CP035945.1\|QBE97591.1\|3567395_3568955_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379258
CP035945.1\|QBE97592.1\|3569181_3570171_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239425
CP035945.1\|QBE97596.1\|3574253_3574796_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE97582.1\|3559158_3559530_+\|RutC-family-protein	unknown	unknown	gnl\|CDD\|129116
CP035945.1\|QBE97580.1\|3557498_3558209_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE97583.1\|3559546_3560533_+\|D-cysteine-desulfhydrase	unknown	unknown	gnl\|CDD\|179673
CP035945.1\|QBE97585.1\|3562121_3562520_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176866

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE97581.1\|3558321_3558984_-\|Transcriptional-regulator-DauR	gnl\|CDD\|225512	COG2964, COG2964, Uncharacterized protein conserved in bacteria [Function unknown].	5.19588e-60
CP035945.1\|QBE97587.1\|3563088_3563841_+\|hypothetical-protein	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.20135e-08
CP035945.1\|QBE97590.1\|3566844_3567441_+\|hypothetical-protein	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.27568e-38
CP035945.1\|QBE97586.1\|3562521_3563073_+\|hypothetical-protein	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.97459e-08
CP035945.1\|QBE97591.1\|3567395_3568955_-\|hypothetical-protein	gnl\|CDD\|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	1.10755e-16
CP035945.1\|QBE97589.1\|3564465_3565737_-\|hypothetical-protein	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.37078e-50
CP035945.1\|QBE97594.1\|3571075_3571777_+\|putative-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.3492e-110
CP035945.1\|QBE97595.1\|3571770_3574029_+\|hypothetical-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	9.30534e-10
CP035945.1\|QBE97584.1\|3560554_3561985_+\|Malate-2H(+)/Na(+)-lactate-antiporter	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	1.49176e-52
CP035945.1\|QBE97593.1\|3570485_3571079_+\|HTH-type-transcriptional-repressor-AcnR	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.00491e-14
CP035945.1\|QBE97599.1\|3576959_3577526_+\|hypothetical-protein	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.01991e-12
CP035945.1\|QBE97592.1\|3569181_3570171_+\|hypothetical-protein	gnl\|CDD\|239425	cd03309, CmuC_like, CmuC_like. Proteins similar to the putative corrinoid methyltransferase CmuC. Its function has been inferred from sequence similarity to the methyltransferases CmuA and MtaA. Mutants of Methylobacterium sp. disrupted in cmuC and purU appear deficient in some step of chloromethane metabolism.	2.39152e-50
CP035945.1\|QBE97598.1\|3575680_3576979_+\|hypothetical-protein	gnl\|CDD\|225121	COG2211, MelB, Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism].	0.000166787
CP035945.1\|QBE97582.1\|3559158_3559530_+\|RutC-family-protein	gnl\|CDD\|129116	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase. This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other].	1.41841e-62
CP035945.1\|QBE97583.1\|3559546_3560533_+\|D-cysteine-desulfhydrase	gnl\|CDD\|179673	PRK03910, PRK03910, D-cysteine desulfhydrase; Validated.	1.03993e-82
CP035945.1\|QBE97585.1\|3562121_3562520_+\|hypothetical-protein	gnl\|CDD\|176866	cd07824, SRPBCC_6, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.92912e-10

>CP035945.1|QBE97589.1|3564465_3565737_-|hypothetical-protein
MMTNTTYDPRLLEQWAIDPSSTQDIGRLLETYLHQYDCAFFSKKQRSHFATFVKGLLSPLDRKSIEPIALHFLDEKSVRPMQQFFTRAPLDEPAILDIYQQLLSAQLNHEGAMLSVDDTSFIKKGIHSIGVKRQYCGRLGKRENCQVGVFLSYAGDSGYGLVDYDLYIPQEWFQDSHQPLRAKCRFPSGRTFLTKNQIAQDLLNRAFQTGRFRARWVGCDAAYGCDHAFLDGLQLPDGVWYFAATNAKEQVFLEPPRIISSEPDRGRGRPKKHPVWSGHPVSVRSLAEAADAPWEPVTLTEGSKGPIQAQRFIMRVVSCRKDGNRNYVKPGEAVWLYVRRYEDGTIKYFVSNAPDHISYTELDRAATLRWPIEQCFEECKSYLGMAHYEGCSYPGWTRHMLFVMIAHLFTIQMRRMAKKKEFR
>CP035945.1|QBE97588.1|3563854_3564280_+|hypothetical-protein
MEYGKYSEVIREQTNRALWEVGNVMACIPDAIWEKEYCGMPLWKHVYHMLHSLDLWFINPDDTEYKEPEIHVKDLNNLDVVTKKTLSRKEVRVYFGDVEKKIKDYTGRLEDEELLLRTKGVSIRDLLLYWHNTGICTPIWG
>CP035945.1|QBE97587.1|3563088_3563841_+|hypothetical-protein
MDKIEMMAVVKGHLADFLECETEIFEQRGLVFHNAGKRAEGYQNPFFQVISLGETIVAAVSPSVRPIAKKLLTGKSREEIFECPLLYGQSIYYIPDAKGNRRTELLPGYTYRELEGDALGQLLGIKGFDNSLMFDERGRTGTHIVFYAERNGEIAGLAGASIESDRVWEIGVDVMEKYRKGGLASVLVNHLMHDILERDILPIYCAASSNAASQAAAFRAGFQPCWISTYKNILDGSSGYDELVRRLYAE
>CP035945.1|QBE97586.1|3562521_3563073_+|hypothetical-protein
MTEEQISIRDRIEIPGEKYVCLTVMGNVVLRMADREETQALTEIRMEYLKDEHGELEHGTAEAIRRQLPGYFARHLGRDLHVFVAVDAQGEMAASAFLLVTERPAKPDCISGKNGTVLNVYTEPAYRRQGIAGQLMEMLLKKAEEMDLSYVNLKATKEGYGLYKKLGFEDGEAIYTDMRYRIG
>CP035945.1|QBE97585.1|3562121_3562520_+|hypothetical-protein
MAKANMKIHLSASAEQVWKVITDNKNYNWRSDLSRIEEMGDGKTFVEYTKSGYPTTFTITRKVPFSRYEFDMENENMRGHWTGLLRESGNGTEIDFTEEVEMKKPFMKFAANMYLKKQQKKYAEDLKKELGV
>CP035945.1|QBE97584.1|3560554_3561985_+|Malate-2H(+)/Na(+)-lactate-antiporter
MDYGFLTLIPPIIAIAFAIAFRKVALALLIGIFSGELILCGWNPITAVNEMVNQILSVCADTGNLKTFLFTTLMGAFVILVRVSGGVNGFVTYLTEQGNKVKSKKMAMMIAYIIGIIIFIDGLLSIMFTGVVTRPLIDKYKVSREKLAYICDSTSAPINAIIPLNSWGAMLMGLIGAEITAGVITGDPMNLLIRSLPFQFYSIVSLVMVLFYILSGKDWGPMKKAEERVRTTGKLYDDGVVPLLNDSEGFDELVEQGKENKWNMMLPLIVLIGGTFTGLLITGKGNITQGDGTTSILYAVTITLLVMGVLYTRQKIMTGKQFGDYVLRGVSNMLTLVILLVLAFAIGGVIKTLGTGTFLASLIGGRISGAFGPAIIFLLGAVMAFSTGTSWGTFSIMMPIAIPMAVAMDSNILLAIGAVVSGGIFGDHCSPISDTTILSSMSVGTDLFSHVKTQLPYALVTASIATVLYIVCGLVM
>CP035945.1|QBE97583.1|3559546_3560533_+|D-cysteine-desulfhydrase
MRPLETFLEKTERVPLMPAPTPLHRLHRLEEQWGCRDIYIKRDDMTGIGPGGNKIRSLEYILGEAVKEGNRVILAAGPAQSNLCTLTAAACAKLGLDCELVHNGAEPEKKEGNLLLNQILGVKSHFLGEVDSDVRNAFVEELFEKYRKEGRNPYVARNGATTGRGALGYTAAVPELMKQCREQGISGMTIFAPGGNGGVAAGLVYGNAVMGNPFRIVIVSVEDDRENLRKHIADTVGEVEAITGIPAGKPVEELCSIEDGFRGQGWGVNTSESAREIFEFARAEGIFIENIYNSKVLVGMRDWLEKGKTKGPVCYLHTGGFGSLFAQY
>CP035945.1|QBE97582.1|3559158_3559530_+|RutC-family-protein
MEIISTEKAPAAIGPYSQGMRISGLLFTSGQIPIDPATGEVVEAEITAQAKQSIENVGQVLAAGGSSFEKVIKTTCFLADMKDFAAFNEVYAKYFTTNPARSCVAVKTLPKGVLCEVEVIAER
>CP035945.1|QBE97581.1|3558321_3558984_-|Transcriptional-regulator-DauR
MNYLILTETDKAILESYKTVLDGLAEYLGDGYELILHSLENLEHSVIKIINGHYTGRVEGAPITDLALKMLDNIRQKKEPAALCYFNKKNGNTLKSATIPILGEKKRIIGLLCINFHTEVSFASILASFTPASSIVPGVTETFSDNVDDLITSALDEAKNKVYANPMISTTNKNKEIIHLLYEKGIFNMKDAVIKVSESLGISKNTVYLHLRNLEKENNT
>CP035945.1|QBE97580.1|3557498_3558209_+|hypothetical-protein
MKKMKSSPQEGNSFNNRIHNLGITTTLIVWAFFLLVPISVCAVFKLNINVKEMLVVAAPIALIFMITGICEKLSMAPIIGPGAVYLASSTGNIQNMKLPAALNAMRIMDCEEGSEKGRVVSILAVATSSFVTTVIVFCGMLFLAPIMTPLLTNPVVSPAFDNIFPALVGPLVIPVLMKNLKVAVVPFALAMCLAVVCGAFYSTIQSILMAAVILVSLGIFGTVYKRNEKKKTEVLE
>CP035945.1|QBE97590.1|3566844_3567441_+|hypothetical-protein
MIYLETERLILRDYTENDAEEYSRLMADDQVMYYLRDIQHHSREESEEDFRNILLDMREKDRQRYFLHIQKKDTGEQIGSIGYTVTDTTPAGKLVHLGYFTYPKYWGCGYVTEALEKVMEFAFSQDGVYRITTGCLRENRGSERVMQKCGMIREAEHVDYEWHDGKMKTRMEYRMLKSDWEKMRQDSTGLNPSKSTKV
>CP035945.1|QBE97591.1|3567395_3568955_-|hypothetical-protein
MKINLDIIAEELSALSPRRAGRQKSDTVKHNLQGAGLYEPQTTLSPEICYAVSADTITETFFCPSGITLAVIGNADEDMLNAFDADILVLNAENAHCTFSDMFNALNSVFLKYQAIHARLTSAVMKNAPLQEILKIGEELFGNPLILFDKNYCILGEADSRLKKLELVCDKWSDSKMLSIDMVNAIKTSPEYRRSSTSSDICFVSDEYFAYNTLFVPVEGNTSPLTAAVMETDRPLTLVHRQLALYFAGILRLALGRNHLSSGHSLRFEDFLKELLYDTQIEQAVIDRYLLAMNWKNGDNYLLVTFQTNRFDKINSIYNNICVNIEKQIAESFAFYFEDNLLTVINLDHARLSKADAVHKLSIFLREGLFHAGISYVFFDFSTFSSYYKQTLGALEMGEKYSPHEWCYDFEDYVLHYFMHYGTSRTDGRHLCHPGVVQLYIHDLKNKTNLLETLRTYLELGGNAVLTAQKLYIHRNTLYQRLKKINGIIHTNLDDANTRLFIMMSYTFVDLLGLSPVES
>CP035945.1|QBE97592.1|3569181_3570171_+|hypothetical-protein
MNLRENAMAIYNREQPDFYGDLMDAIVLVPDPVLMGDMCPQDGLEHKDSWGTVYIFKPGAPGPHPRVNKENAVIKDIEKWEEQLTVPDLEHLDWTLVKEEAAKVDRKEKFVGFMCAGGLFERSHHLMGMEEALVNYLEYPDEMAGLLRVIADYKMKYIKMVAEQIHPDIIFYHDDWGSKQNVFLPPRVWREIIKPLQKEIADTIHACGMIYMHHADCICQPIVTDMVEIGVDIWQGAIAQNDIVEIQRVTEGKLAMVGGIDGPKVDIENITEEEIRAEVRRAIDTYCPGGRFYPSIPNGICFREWNNSIVMDELHSYGRKYAQEHPVVK
>CP035945.1|QBE97593.1|3570485_3571079_+|HTH-type-transcriptional-repressor-AcnR
MQTKKDEIRKTILEAAQKEFLIHGYEGASMRTIAKKANTTLGNIYHYYENKEAILEELMREPVEKVKKMIDDHMKLQDELFTMSEMQGFLNDLDNLMDYHEMQCLMDERLVILFDLRTTRFVKIRDDAIHKFKQHLAWHLGMDDDDSAYVDIIMNTFIACVRHVLSEHKGTEESKKEFVKVFKVLCAGVLSNGKEEK
>CP035945.1|QBE97594.1|3571075_3571777_+|putative-ABC-transporter-ATP-binding-protein
MKIVELKHVSRYYKAGQQKNYALKKVSFDIEEGEFVVILGASGAGKSTMLNLLGGIDRADEGEILVAGEDIAKLSEKELSKYRAKRVGFVFQFYNLIPTLTVKENVELMRELKKDALEAGEALRKVGLSGHEKKFPEQLSGGEQQRVSIARAIAKNPDILLCDEPTGALDSETGCMVLSELQKLCRSEGKTVLVVTHNANIARAADRVIHIRSGEIKSIECCDDPCSVEEVEW
>CP035945.1|QBE97595.1|3571770_3574029_+|hypothetical-protein
MVILVRKMLRDIRKNKVQFAAVFLMMFFGCFLYSGITGEWGGLKKHFEDYIRSQNLADVWAYDTAFTKEELEKLEQDSRVTEAEGRMAVPMGIQGQEDASLDCIFAKDNRISKLYIREGIPFDSSKKGIWLDASFAEENNLKVGDRLTLTYQGLEITGEIAGLADSPEYIYGVRDGSMMPEHRLYGFAWISPRLLPSEELYSVNQAAVKTKEKQSTKLLREILENPDLTVLEAEKHPTVSMVQDEIKQHKTIGSAFSSAFLMIAVMIVMTTMHRMLRNQRTQIGILKAFGFGRLKLLIHYLSHSGTICFCGALAGCVLGCRVMPGIIYPFMKEIYVLPEWGGYLPPVYLLLPVICVLFCITVSLVICRKYLKGNASECLYREESGRRTVSLPEICRHLPFSSRWNLRDVERNRLRSFMTLCGILGCTALLFCAFALFDTFQNLSEWTFTKQQGYECKITNLPDTEGQRLLLSRTEGEYLMETSAVIKDGKKEKEVSLTVPESTKYIKLAGSLDDFVGIGDGIALSKKTADSMGLKTGDTVTWKQSGEKEWRDSKVEAVIRTPLSQGITIMKSSFEKEQGVFVPTGIIGKEPVRGFAGYEKECSITHQSDLTKGIDAMMEGMIMMIALLVLGAVILGGVMLYNLGVLSYLERGREFATMKVLGFADMKIRSVMVEQNVWLSAAGILLGLPAGYGLLIYMLSTIPESMDVPIFIKGMSWIFSAAGTLALSWLISLAVSRKIPHINMVEALKAKE
>CP035945.1|QBE97596.1|3574253_3574796_+|hypothetical-protein
MEKQIFELLTKNRQKDELAMLDAYNQKTEMFGLALTKEEAKALIVSRDESLKKYGRVEFGKGILDKLVYSFCDSQYISRENYLAVLTRLQDIFYHFKNESQDKLTDDELLTFMRQQYESVCYGDLDYLENTCLERFSKAVRGGYRGFTKSGGADEYEELSEETRWDAELYQSVLKELFWE
>CP035945.1|QBE97597.1|3574835_3575672_+|hypothetical-protein
MEYQLEELLPITAWLADKYTSKESSSVTYDTAQMLMESVIYCVKECGDISSNALMGKQAMKAEDAYKIGYDRVVEKVHKAKAIYDKLSRDFCDYGCSNYRATVLEGMPSFFIFYDARFRPQDHLLTLDYPTVNFSGEMCGIDIIYQYLCDIVLEKGFLECFPQQAVRQLLGRIQSRVGTAYMGNISEMVLVTAFGCMIADRRLSELSLCSQDMDAVKQYFSGDDLQRTEGKLKMLLRVLAEKSGRQEWIPYFDRLCHEYAVRIQNGMGYGTLETVFFG
>CP035945.1|QBE97598.1|3575680_3576979_+|hypothetical-protein
MERKTKYVLPWIIYLGSLMGFGLAKFILQGIGVEFRIWVQALFWVLAFLFPALLIGYYLTRIKYKVLAVVVTIIYAVLAVIVFLAGFFYFLFTSPTEYDIGLGMICVAEQSGGYTSDYTYWDKISFFGRKKFEWDEERDIRLLEDKYGMDFEKSSGAYRNEKYPDIAVHILRYPIGSGSELSDDFIDNIQAYYFKKTYEEKGFCTKWSEEEENGITGYRLIVNSEAEMRQASKEAAEMIAGAIEDPIFEKFTGALQVEIEVKGSVRLCSLTFGGAEESDQVERDRAYYTNADNTEKTLEQTYNELLDSLEESEMMEQIREDTDKENQDYFSRMESSYDFLYENELSKQYTTSEKMYNAKGNFYAVLGGDTAEYENEADRPYEVTVVYDRVSDDGDSLLFVMYKKYHEKADTAAGYSVNLDAGEVEEYDVPWF
>CP035945.1|QBE97599.1|3576959_3577526_+|hypothetical-protein
MMSHGFKKGIALRKAEASDIETAAYIHATAWQQSYRGIFDEVYLLSQSVEVRKKEFLERMHEDDSFDYLVFKGETPIGILILSTVSESCMEIESLYIIESFRNSGAGTAAVDFAVNKARELEKREISLWTLACNKKARQFYMRNAFDETDEKRTIYRGDSFSQIKYSRTIYPQADEEKNGKGKWKVYE

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Crispr_ID: CP035945_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_10

3862452-3862883

Unclear

Consensus_repeat	Method
TGTCACTTCCCTTGCGGA-AGTGTGGATTGAAAT	PILER-CR
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CRISPRCasFinder
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CRT

6 spacers

cas6

The CRISPR arrays of CP035945_10

>merge|CP035945|10|3862452-3862883|PILER-CR,CRISPRCasFinder,CRT
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAATTGCAATAAGCCGGTAAAACCGGTTCAGGTGACAGTGTCACTTCCCTTGCGGAAGTGTGGATTGAAATCATATTCTGTTAGCTTTTGCTGGCTGTCCTTTTTGTCACTTCCCTTGCGGAAGTGTGGATTGAAATTATCAGACTGGCGGCGTGTACAAAACTCCGCTTTATGTCACTTCCCTTGCGGAAGTGTGGATTGAAATCATCAAGAACGGAGTTGTTACGGCAAGTGGGACTGTCACTTCCCTTGCGGAAGTGTGGATTGAAATAAAATAGTATCTATCAATCCATCGCGAAATTTGGGTCACTTTCCTTGCGGAAGTGTGGATCGAAATCAGCAACAGCAGTTTACGTTCCCCATTGACACCTGTCACTTCTCTTGCGAAAGTATCGGCTGAAAG

>CP035945|10|3|3862452-3862817|PILER-CR
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	TGCAATAAGCCGGTAAAACCGGTTCAGGTGACAG
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CATATTCTGTTAGCTTTTGCTGGCTGTCCTTTT
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	TATCAGACTGGCGGCGTGTACAAAACTCCGCTTTA
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CATCAAGAACGGAGTTGTTACGGCAAGTGGGAC
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	AAAATAGTATCTATCAATCCATCGCGAAATTTG
GGTCACTTTCCTTGCGGAAGTGTGGATCGAAAT

>CP035945|10|10|3862452-3862883|CRISPRCasFinder
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	TGCAATAAGCCGGTAAAACCGGTTCAGGTGACAG
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CATATTCTGTTAGCTTTTGCTGGCTGTCCTTTT
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	TATCAGACTGGCGGCGTGTACAAAACTCCGCTTTA
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CATCAAGAACGGAGTTGTTACGGCAAGTGGGAC
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	AAAATAGTATCTATCAATCCATCGCGAAATTTG
GGTCACTTTCCTTGCGGAAGTGTGGATCGAAAT	CAGCAACAGCAGTTTACGTTCCCCATTGACACC
TGTCACTTCTCTTGCGAAAGTATCGGCTGAAAG

>CP035945|10|3|3862452-3862883|CRT
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	TGCAATAAGCCGGTAAAACCGGTTCAGGTGACAG
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CATATTCTGTTAGCTTTTGCTGGCTGTCCTTTT
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	TATCAGACTGGCGGCGTGTACAAAACTCCGCTTTA
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	CATCAAGAACGGAGTTGTTACGGCAAGTGGGAC
TGTCACTTCCCTTGCGGAAGTGTGGATTGAAAT	AAAATAGTATCTATCAATCCATCGCGAAATTTG
GGTCACTTTCCTTGCGGAAGTGTGGATCGAAAT	CAGCAACAGCAGTTTACGTTCCCCATTGACACC
TGTCACTTCTCTTGCGAAAGTATCGGCTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE97831.1\|3861135_3862044_+\|hypothetical-protein	cas6	mkCas0091_cas6_CAS-I:CAS-III	gnl\|CDD\|337605
CP035945.1\|QBE97828.1\|3857760_3858693_+\|Elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
CP035945.1\|QBE97838.1\|3870160_3870892_+\|Polyprenol-monophosphomannose-synthase	unknown	unknown	gnl\|CDD\|133022
CP035945.1\|QBE97836.1\|3866996_3867905_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE97833.1\|3863447_3864173_-\|Sensory-transduction-protein-LytR	unknown	unknown	gnl\|CDD\|225818
CP035945.1\|QBE97842.1\|3875445_3876945_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225153
CP035945.1\|QBE97832.1\|3862179_3862329_+\|hypothetical-protein	unknown	unknown	unknown
CP035945.1\|QBE97826.1\|3855916_3856744_+\|Acetylxylan-esterase	unknown	unknown	gnl\|CDD\|223730
CP035945.1\|QBE97837.1\|3867915_3870171_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224206
CP035945.1\|QBE97827.1\|3856946_3857687_+\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
CP035945.1\|QBE97825.1\|3853948_3855901_+\|Fructose-1,6-bisphosphatase-class-3	unknown	unknown	gnl\|CDD\|377726
CP035945.1\|QBE97829.1\|3858934_3859864_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	unknown	unknown	gnl\|CDD\|378820
CP035945.1\|QBE97835.1\|3864863_3866996_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223528
CP035945.1\|QBE97823.1\|3850880_3852518_+\|Serine/threonine-protein-kinase-PknD	unknown	unknown	gnl\|CDD\|270916
CP035945.1\|QBE97834.1\|3864476_3864833_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378376
CP035945.1\|QBE97841.1\|3873968_3875411_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379904
CP035945.1\|QBE97840.1\|3872545_3873967_+\|Putative-glycosyltransferase-EpsD	unknown	unknown	gnl\|CDD\|340841
CP035945.1\|QBE97830.1\|3860043_3860736_-\|Iron-sulfur-flavoprotein	unknown	unknown	gnl\|CDD\|377026
CP035945.1\|QBE97839.1\|3870863_3872549_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378327
CP035945.1\|QBE97824.1\|3852514_3853924_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE97831.1\|3861135_3862044_+\|hypothetical-protein	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	8.55654e-07
CP035945.1\|QBE97835.1\|3864863_3866996_+\|hypothetical-protein	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	3.59169e-09
CP035945.1\|QBE97839.1\|3870863_3872549_+\|hypothetical-protein	gnl\|CDD\|378327	pfam09960, DUF2194, Uncharacterized protein conserved in bacteria (DUF2194). This domain, found in various hypothetical bacterial proteins, has no known function.	5.71321e-15
CP035945.1\|QBE97833.1\|3863447_3864173_-\|Sensory-transduction-protein-LytR	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	2.66844e-20
CP035945.1\|QBE97842.1\|3875445_3876945_+\|hypothetical-protein	gnl\|CDD\|225153	COG2244, RfbX, Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only].	1.80304e-09
CP035945.1\|QBE97838.1\|3870160_3870892_+\|Polyprenol-monophosphomannose-synthase	gnl\|CDD\|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	6.12567e-43
CP035945.1\|QBE97828.1\|3857760_3858693_+\|Elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.57773e-128
CP035945.1\|QBE97837.1\|3867915_3870171_+\|hypothetical-protein	gnl\|CDD\|224206	COG1287, COG1287, Uncharacterized membrane protein, required for N-linked glycosylation [General function prediction only].	0.00387346
CP035945.1\|QBE97827.1\|3856946_3857687_+\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	7.91275e-173
CP035945.1\|QBE97825.1\|3853948_3855901_+\|Fructose-1,6-bisphosphatase-class-3	gnl\|CDD\|377726	pfam06874, FBPase_2, Firmicute fructose-1,6-bisphosphatase. This family consists of several bacterial fructose-1,6-bisphosphatase proteins (EC:3.1.3.11) which seem to be specific to phylum Firmicutes. Fructose-1,6-bisphosphatase (FBPase) is a well known enzyme involved in gluconeogenesis. This family does not seem to be structurally related to pfam00316.	0
CP035945.1\|QBE97829.1\|3858934_3859864_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	6.60625e-36
CP035945.1\|QBE97840.1\|3872545_3873967_+\|Putative-glycosyltransferase-EpsD	gnl\|CDD\|340841	cd03813, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.	5.25638e-164
CP035945.1\|QBE97823.1\|3850880_3852518_+\|Serine/threonine-protein-kinase-PknD	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.45786e-53
CP035945.1\|QBE97834.1\|3864476_3864833_+\|hypothetical-protein	gnl\|CDD\|378376	pfam10066, DUF2304, Uncharacterized conserved protein (DUF2304). Members of this family of hypothetical archaeal proteins have no known function.	3.54569e-18
CP035945.1\|QBE97826.1\|3855916_3856744_+\|Acetylxylan-esterase	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	5.27329e-22
CP035945.1\|QBE97830.1\|3860043_3860736_-\|Iron-sulfur-flavoprotein	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	4.02939e-18
CP035945.1\|QBE97841.1\|3873968_3875411_+\|hypothetical-protein	gnl\|CDD\|379904	pfam16933, PelG, Putative exopolysaccharide Exporter (EPS-E). PelG is a family of putative exopolysaccharide transporters like PelG. Most members carry twelve transmembrane regions. The family also contains fusion proteins with glycosyl transferase group 1, which are putative flippase transporters.	9.88723e-112

>CP035945.1|QBE97832.1|3862179_3862329_+|hypothetical-protein
MDFNKDFIIAAVHIEGNRIGTRSYESFINVRCEYGVNIVFQGDSHLKKV
>CP035945.1|QBE97831.1|3861135_3862044_+|hypothetical-protein
MFEFINILTLRATYECQEEGRLPSYLGSTIRGILGHCIRDFCCEYPAKRCFQCEKKKGCLYVQCFSNTGGEAGAVNPYVLYVHGEGRERWKKGDLCVFDLTLLGRGGERAGVYLDALLAAEQKGWGAARLSFRLMQVIDSGSGKVIYAGGKSWIRNLSPRPLQTAGRNASYASLFFDTPLRIVSGDKLFDKLPFETFMQFLIRRISLLTKAYTDYQLEWNEEELLNQARKIKTLDEYWREIPFTRYSMNQEEGKLKLPSRTGWVLYEGDLSSFVPILEAGKFLRVGKGATIGFGHYEISYDK
>CP035945.1|QBE97830.1|3860043_3860736_-|Iron-sulfur-flavoprotein
MKITVIHGQNHKGSTYHIAKMLYEKLDGEVTEFFLPRDFHSFCIGCTNCFEKSEILCPHYEDLKYITESLDSADVIILASPVYVYHVTGAMKVFLDHYGYRWMVHRPEEKMFQKQAVCISTAAGGGMKSTTKDMADSTFFWGIAKTYKYGVGVAAVSWNTVDSKLKNRIDKKTTVLAKKIKINLGHVSPGIKTKAFFHLMRFIQKKGWNDADVNYWNKKGWNGKNRPWKL
>CP035945.1|QBE97829.1|3858934_3859864_-|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase
MLHEVSFPSYNKRDQVQGWIYAPAAKPKGIVQIIHGFGEHSRRYLHMIVKFMDAGYIVAADDHVGHGKTAMVSGVWGDWGDAGFRTMMEDEHTLKKVVCEKYPNLPYFIFGHSMGSFIARDYAAKYGDDLAGVTICGTTGIFRGADNAAELLKKSLDDGRGMDSDPEFTGILMGWMCERCDDVTIGNEWICADPYVQRDHAEDPFDAFTKPTSNRSLFDFTQMMMAVEGIQWAEKVPKSLPFYNIGGDQDPVGEYGKGIYEVSNWLCDTGHNVITKVYSGYRHEIHNYSDIKNDVEAGIIAFMNGILDI
>CP035945.1|QBE97828.1|3857760_3858693_+|Elongation-factor-Ts
MAITAGMVKELREMTGAGMMDCKKALAATEGDMDKAVEFLREKGLATAQKKASRVAAEGLCKTLVSADEKKAVVVEVNAETDFVAKNEKFQGYVAQVAEQAMDTEAADIEAFLAEAWKFDTTKTVQEALAGQIAVIGENMNIRRFTKVSEENGFVASYTHMGGKIGVLVDVETDVVNDAVKEMAKNIAMQAAALKPLYTNRNEVSQEYIEHEKEILTAAAKNEKPDANDKIISGMVMGRINKELKEICLLDQVYVKAEDGKQTVAKYVEEVAKANNAKIAVKGFVRFETGEGIEKKEENFAEEVAKQMGN
>CP035945.1|QBE97827.1|3856946_3857687_+|30S-ribosomal-protein-S2
MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIYTERNGIYIIDLQKSVGMVDDAYKAVADIAADGGTILFVGTKKQAQDAIKVESERCGMFYVNERWLGGMLTNFKTIQSRIGRLKEIEAMEADGTFDVLPKKEVIELKKEQTKLEKNLGGIKEMKKLPDAIFIVDPKKERICVQEAHTLGIPLIGICDTNCDPEELDYVIPGNDDAIRAVKLIVSKMADAVIEANQGAAEDSEIFEEAVEEEATEE
>CP035945.1|QBE97826.1|3855916_3856744_+|Acetylxylan-esterase
MIHEKIPIQMSGSSKDTHLTTYILDAYEEQPEDLVRPLILICPGGAYRFTADREAEMIALQFNSMGYHAAVLRYSCAPCVFPTALTEVARSVQMIHEQAKAWRVDTDNIFVMGFSAGGHLAASFGVFWNRDFLREAVGCSKEILKVKGLILCYPVITSREDYGHLESIHNLLGSEYEEKKAMMALENQVDIHVPPAFIWHTFEDQSVPFQNSLLFVEAMGKAGVPAEFHLYPKGSHGLSLANEALMRTDGTGVQEECQSWMPLLRTWLWNACGRK
>CP035945.1|QBE97825.1|3853948_3855901_+|Fructose-1,6-bisphosphatase-class-3
MEKLEHKYLERLSELYPTIAKASTEIINLQSILNLPKGTEHFLTDIHGEYEAFSHVLKNGSGSVRRKINEVFGHTLNEQDKRSLATLIYYPKEKMELIKKTEENMEDWYKITLYRLIEVCKRVASKYTRSKVRKALPPDFAYVIEELITEKPELNDKEAYYEQIIETIIAIGRAEVFIIALSELIQRLVVDHLHILGDIYDRGPGPHHIMDKLEEYHSLDIQWGNHDIVWMGAAAGQRSCIANVIRICARYANLDLLEDGYGINLLPLATFALTYYQEDPCECFKIKGGNTLNPAETVLNMKMHKAISIIQFKLEGQLLIRRKEFHMADRALLDDINYEDGTIRLYGKEYNLLDHAFPTVDPENPYELSKEEEEVMERLVSAFANCEKLQRHMQLLLKKGSLYKVYNNNLLYHGCVPLNDDGSFKEVEIYGRTYKGRELYDVLESYVRKAFFALDKEEKQRGRDILWFIWSSPASPLFGKDKMATFERYFLAEKETHVEKKNSYYRLLEDENVVDNIFREFGIEGDCCHIINGHVPVHHTSGESPIKCGGKVLVIDGGFSKAYQKETGIAGYTLIYNSWGMILAAHEPFTSAEDAITRESDILSDSILVKRTSLRKTVGDTDNGHHLQESIDELKQLLKAYRNGQIIEKE
>CP035945.1|QBE97824.1|3852514_3853924_+|hypothetical-protein
MKRNLMLMAAAVILLYSCTAVSVLASETDRDAHRDMDKELPEITQIVELRKGEELFLPDNGFVQIKDERIACTGSNGNIEALEEGETEVVVRYRIRVKNTVPKEETDSTHSDKNGKENDALDKVGEEEKDAEKGVQGIEGGKSDTEGDESDTEGDKSNAKGDKSDTEESNPDTEEGMSDTKGGKPDTEGGRSDTEVGKGKDMFNIENGKNGSGKEQKTNGQPSLHSMTEIEIPDCRCPVVTLANLKNLSSNNSRVAPCIIVQDENLDKSSVKIRLTGKRTGERNISFQKEENRDGLSLTLDPVTEDDEYILICRASDIYGNQTEQRFLFSVNQSGTSFLFDREESTYSTGFSPEITLDNTDAIQIISCAVNGEPVLYEWEEGKLRIPTEYLKSGKNRITLSVRDTAGNINDMEPWDFIMPLKEDAEADTMPGPEAVKMQKENPAGIIFLLIGSVLVFWEKKMCYNGSMD
>CP035945.1|QBE97823.1|3850880_3852518_+|Serine/threonine-protein-kinase-PknD
MYEEKCLLGGRYRLEKVLGKGGQGKVYLAFDMKLGKYWAVKKIPDGSSREAEIMRHLEHPALPRITDILEENGYRYLVMDYLEGFTLEEIKKSGKRIPWKKRIKWAIQICSLLEYLHGPAKGIIYQDMKPSNLLVHISGDMRLLDFGIAFLSERGSSAENSHSAESGHSAENRRSMVGYGTPGFAAPEQFLGNAEERTDIYGFGAILLYMGQKDEGKSKLHKKWRQIAEKCMETSMGKRYRNISAVKRELQNLEDWTQNRKRVRAGSIFLAVGLLLLLGAQVRRQELLLDAGRLLGIREGTGLLDTADYGEARRYFLREQEGTEKGEMYRIILDTIEEMPVKANWEEAKKAVKALENSEGTSWEKAGEKIFLANVVQAYDTELGYAKKEGTKKARDLLRQAEINVKENIRKTYAPIYLMEVWYQLAKVCEKLDDPVQSIDYYKLILNEKIPVDLEQEVRLSAAAMYRQMKNYSEAEKWYENYLRDYPRDAEAYCAYALMEAMERGNWKKAEHLLSLMDQRGAEKSGFNSEKIKSRINELTKEETE
>CP035945.1|QBE97833.1|3863447_3864173_-|Sensory-transduction-protein-LytR
MRFAIVDDLAFCREEIKKNLFRYIGENFAGEHPQIDEFDSGELFLENFSPETYDMIFIDQYMNGISGIDTAKKIRESDNLVALVFITTSRDHALDSYEVRASGYLVKPYKFKDFSRTMELVNMIKLRNARFISIGGRKILLREILWCDRDEHYVQIHTDRQGILRLRLSFAELEQLLLPYIQFLSCYRGCMVNMDRAVKIHNLNFIMDTGEAVPFRKRDRGNIEKQFNSYLFQREREEWLF
>CP035945.1|QBE97834.1|3864476_3864833_+|hypothetical-protein
MGWILKIFAVLVGVFMMCMVTRTAKQKKMNEVQSVFWFIGAIGIIFMGLFPGVLAWMANILGVWWAPAILIFFLIVLLLFIGFNHAKEISILKAEVTELSMQVSLLKYEKEQREAKES
>CP035945.1|QBE97835.1|3864863_3866996_+|hypothetical-protein
MKILICSNYGDICNRLIERLKKEKQEIYLITGSQETQKNSAFQTYAFPYGSESIPRIFNNVRPDIMIVMGCFDPLYSWRDEQKQSVEYISGLSNLILAAKHVGVRQIVYASTLDVYEQNGREEIVKETLPLAGSLRLKTFLQAERLLSEFAEESFEMSVLRFPEIYGKLDYDRFDVCQRMVRECVENQKGTYYPGIYHRILYMDDAVECMMQCVFREKTESMYWIRGEEYKEEQIVDTLKKISEKSGSPVEWESCSLEAEEVPHRLELDHKLCGYDLVRIKYPMETGLEHLYHQCRQKNIKENKKKQLKESAWEKVMIPALETVGLFILIVLLSRWLSHTWVKDSLNLYLIYVVIIAATYGIAHGLFASALSSVFQIAVLVSSSGIQVFSNDYSVFVGILEIVVVGVLTGFMRDKYKRKNNDLSDENTYLSSELKDIEKINDSNAYVKQIYEERLVNYKNSMAKLYEITAQLDFMESRKVMFGAIKVIMNMMDTKDVSIYVSSKKSGYYRLNASGSEKAAGLGRSLCIDHSSSLYRTISKKEVFVNREMNPDYPVYAGATYSGEEIEAVIMIWVEDLNKINLYYTNMVALLCRLIEKAVARAILYEQSIFRDACLEGTEVLNETAMAKAIQTCQEGRNQGLLEYVILETGIKDASVFEQVRRYIRDTDVLGLHEGTLWILLTNTKTEDAQYVIARIEQAGLSSQIVEWKE
>CP035945.1|QBE97836.1|3866996_3867905_+|hypothetical-protein
MWIMKWLIILLIVNAVTALIYVLIQMGRKKWQRGLTAGLFMLAVPVVGAVFLAVSEGINVLLFRKRDFLLDSSELSFNKQRTKTVNAPDIGKSSDQVPVEEALLVSDKKDKRQVFIDLLKKEDYEKSLEVIRQAVEDEDMEISHFASSFISDTVSRYKEQEERLRKNCEDRKEESLVRYAEYLLNMLQYDIFSVPERRTYLERLEGAFNCLEEKESSLITGTMLARAMTLWSKLGEPGKEELLVQTAEKYALKDLEALKICLKYYMKKGEREKFFALLEEVKKSSLTLDGEVLEWLRFYEHK
>CP035945.1|QBE97837.1|3867915_3870171_+|hypothetical-protein
MIAANITNIIEFAAGYALVVIFLPSLCFHAFVREKGWLYRICFYQTIGNVYLISIGYLLAYMKCFYRWSVLIFMVLIPLLLNLLVRRKSVAAFLRERRKNIKDIAAGVYGRRKLRRDLFMIGKDHVQNYYRENIKGNLLELALVFLVMAFVLYFFGMYKFTSAAYGHTDEETHLYWIQSLLDNNIFPVGMYPFGLHFLTGVISTVLGISAVRTYLNIAVFSTFMIFLSVYILLRSLIRSRFAALGAWAVFAVSDIFTTVTYFRFQFSFPMEFGLVALMLMLLGLISYVKEKENTSLWMFILSVFWCFQAHFYVAIIAGILCVCFGIVFCVRMLRDKMLFKVIAGGILALILSMLPYGCGYLLGYPFERSINWALSIMQGDYGMETLEQQYEEETEKASQNASGEEKDDEDEPEFDLSKVHSPEDAVRTVLEMLASKTVSSMFYAKIILALNAFALLYGLFGIIFAKEKWQYLIYVFLALAWAALFALHSCYLVGAPVLVEMYRAATFLAVFTVPLLAMPGQFCYDCLIRCGVQKKIADYLVLAAGCAVMGAICSHGAVKKGRYFEMTVTEADMRVCMDLIDNYKKETWTVMSTTNDLSAVWRDGYHYEILDLLDKLEKNKRKIFIPTKYIFVVTEKNVTQYYESKRKIDRSNVIDFTVPVSPELARQDLHIPEEGSKGRDRLYYFQRQIVMSKLYYWMEQMKVVFPNEISVYYEDDCVTVYKIQQDEYFLLNLAVDYTKSIPAEEEDGNGS
>CP035945.1|QBE97838.1|3870160_3870892_+|Polyprenol-monophosphomannose-synthase
MDHKVVLVIPAYNEQANIGNVLRKIQEINTDHWLDVVVIDDGSSDNTYGEALACKVTVIRQVYNMGYGAALQTGYKYAVEHGYEYLLQMDADGQHDVRNLERIYRELTAIQERQPDIVIGSRFLSASQTYPVSKIRLVAIRMFRFVIRRLTGYTLTDPTSGLQGLNRRAFSCYASYSNFDIKYPDLNMILQMLLRGYHITEIPAIMHIRTEGIAMHSGAAHAVKYMILMCLSTFNAFIRYKRK
>CP035945.1|QBE97839.1|3870863_3872549_+|hypothetical-protein
MRLFVIKESKGDFVDRKKFQTKNQLKRYTYVYIVLILFLLLSAFLLLANLSKIMMWAENKKEKPQSTAAKAEDAVQDSELERAHACVIGSENPDLQELIELQMTVMKESLGSVQSIDDLRGRELPELKLLIITTEKITEQDTEWLEEQVKKGKHVFFAVFPDDTSLKSRRLRNLLGIYRLGKETVYEAMRTSQNLLLGTISESEDSHIPAREIELKKQTQIYISALLEDEDVENEDLPPLFWSYVGEKGDGFVYVSNGQLAETPLGYAMLSMIFCDLSETYIYPVVNAYCVAVKGMPYVSNIRSDILEKRYSRDARGVQRDLFYPELKRCSDIYGIRFSYFTPDHGSDALEKEGELVYFCQEIEAAKGEISRILLDGTMEIADSSSRAVEWTEDFQFRDGKDQRLNVPLLLDNMSDYLQERQFVDGGLRGLGMITGLIDIPEILEDEDEDEKLEWMEYCKIMETAMGTHKKYYPWIDRVTLSEAAGRIENLLAIEPKYTYSSDGVRIDIGNFEKEAYFYMQTPNKITGTEGGEITKIGEELYMIRANNSQVKIDWKQEVME
>CP035945.1|QBE97840.1|3872545_3873967_+|Putative-glycosyltransferase-EpsD
MKVCLIVEGAYPYVNGGMSNWIQQLMLYMKDTEFIVQSIAAKREETRSFKYQIPDNCLEIQEVYLLDDDYMSNRRQKRLKMTSEEYEAFEGLLFGKEVDWKTIIRFFAEKEVSLNALLSGEDFLSMVLAYYKEHFARIPFTDFLWTMRSMYLPLFTMLKSRTTEADLYHSASSGYAGIWGAMQRYLYDKPFIMSEHGIYTREREEEIIKADWVKGIYKDLWIMQFRKVGMCCYDFADQVVALFEEARQFQIELGCIENKTMVIPNGVDSHKFENIPQKQEEDPFIHVGAVLRVTPIKDVKTMIGAFGLAKSKEPRLKLWIMGSLEESEEYAQECRKMVADLNIQDVEFTGIVNIKDYIGKMDILLLTSLSEGQPLAILEGFAAKKPFIATNVGNCRGLIQGEFDDWGDAGYIAPVMNTSKIANAILDLAGSPEKRKRMGETGYRRVCTFYDEKNIFEQYYQLYQRMAEKEKVK
>CP035945.1|QBE97841.1|3873968_3875411_+|hypothetical-protein
MAGIGFELKKIYRKEGIARAVAGGIYSSVVTIGPTVVVIVTLLFLYLALNMMKVSFMTRELLSSTILYVFIFSIILTAPFNAVFSRYLADKFYMDEYANILPSFYTGILILGILGTGISIPVMLSLYFRGGIDLPFILAAYVFWMSSVLLFFSVTYLHATKDYKIIAIFFLVGMLVVVLTALVFRFVLRADRIHSILYGMAAGFLTIAVLEFSYIKRYFRTVSQNYTECLWYLVHHGKIWLTQLLYMLGLYVHNFIFWTTQQRLTVAQTYHSHQSYDMASCLAMFTNISTMILFTVVAETRFHEAYQDYMESIIGGTYKAIQKNKKIMFRTLSQQIGQVFGMQLAITSVIFLVLLIFGPYIGFSGMIMEIYPVLAVSYLGIFLLYGNLVYLYYFDDTKGTLLSALAYFAGTVLGTLVSKNLPVAFYGMGAFFGMLCGFTASYFRIRYLEKNFEAHIFCHYKIIDTMKSSQKGRIVYQKQA
>CP035945.1|QBE97842.1|3875445_3876945_+|hypothetical-protein
MSGGDSRLQSNVIIGVFHQVLSLLINMVSKYAVRTYLGVEYLGLQTVFGNFCDIFTFAFMGIGTAMMYSLYRPLALGKRKEQAEIYQYYRRIYRILTVAVMSIGSAAVFLVLVVVHADIRVMEITGTYFLYLGSVLIYNRLFLEYYYIMADQKRYICCLVMSTVDGAALVFQVFVLKTAYNYSLFLLCVLVKNIITYFILHSYIKRRYSHLLQEEEMPGTAEQKEIRKNVKDLIIYRAGNVLVNSTDSIVISDLLSTATAGCYSNYMFVSMGIQSMISSFFDSILAKIGHSVSLDGRDKQYSDFLKLSAVNIMVNGITVIGFYWLVQDFISLWMGAEVLLDMKVPAIVALNLYLTGIRQTTAAYRQSAGLFQKVGYIVLGKGLLNLVLSYILGAVYGLMGILTATAVSSVITLYFYEPYMVYRYFGKSWKPEAVYQIVSGGLTYVILRIVGIPLQAMPAHSWFWLCIKGMLCLLLSLACFFLFGAVLSKIIKKLGEKQL

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Crispr_ID: CP035945_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP035945_12

5392187-5394093

Orphan

Consensus_repeat	Method
GTCACTCTCTGCGAGGAGAGTGTGGATTGAAAT	PILER-CR
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CRISPRCasFinder
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CRT

28 spacers

WYL

The CRISPR arrays of CP035945_12

>merge|CP035945|12|5392187-5394093|PILER-CR,CRISPRCasFinder,CRT
ATTTCGATCCACACTCTCCTCGCAGAGAGTGACGTACCGTTGTAATGCCTGATTTTGTGATCCAGAATTTCAATCCACACTCTCCTCTCAGAGAGTGACTTTCTTCTCTATCAGTCCCACATCAGCCAATTCTATTTCAATCCACACTCTCATCGCAGAGAGTGACCATCCGTCTACTATAGCATTTAGCGGAGATTTAAAATTTCAATCCACACTTTCCTCACAGAGAGTGACGATAGTGCAAGAGTAAACAAGAAAAGCGTATCCTGATTTCAATCCACACTCTCCTCGCAGAGAGTGACGGCAAGGATTATCTGTATATCCCCGAGGCCGTGATTTCAATCCACACTCTCCTCGCAGAGAGTGACAACGATTGAGAGGTGGTGAGGCTTGGCAAGACCGAATTTCAATCCACACTCTCCTCGCAGAGAGTGACAGAGCATACAGAGAGAGGATGGCAACCATAATGATTTCAATCCACACTCTCCTCGCAGAGAGTGACGAGACGAAACGGTCAGACCGAAACGGATAATAAGGATTTCAATCCACACTCTCCTCGCAGAGAGTGACGCCTCCGGTCCAGATCTTGCCACCGTCTTTAGACCAATTTCAATCCACACTCTCCTCGCAGAGAGTGACTTATGCGCTGGTGCTCGGCTTCTGCACCTAACAAATTTCAATCCACACTCTCCTCGCAGAGAGTGACTATATGGATTCATCCCCAGGATTGCTGATGCGTCGATTTCAATCCACACTCTCCTCGCAGAGAGTGACAGCAAAAGAACGCGTCATCCGAAACTCACAGGGATTTCAATCCACACTCTCCTCGCAGAGAGTGACTTACACCTTCCTGGTTTATATATGATCCGATCTATTTCAATCCACACTCTCCTCGCAGAGAGTGACGCATAGAATCTATGCTTTTATTAAAATGGGAAGGATTTCAATCCACACTCTCCTCGCAGAGAGTGACCGGACTGTCTCGACGAAATGCAAAATTTGATAGCGATTTCAATCCACACTCTCCTCGCAGAGAGTGACTGGAAAATTTAAAATACCAGACGATACACTCTTATTTCAATCCACACTCTCCTCGCAGAGAGTGACGAAGCTATTGAGATGACACCAGTTGAACTGAAAATTTCAATCCACACTCTCCTCGCAGAGAGTGACTATCATAGGCAAGTGTCAGGCCACAATTTATAATATTTCAATCCACACTCTCCTCGCAGAGAGTGACTCAAAAGCCTCCATCAAATATGCATCGTCAGAAATTTCAATCCACACTCTCCTCGCAGAGAGTGACTCAAAAGCCTCCATCAAATATGCATCGTCAGAAATTTCAATCCACACTCTCCTCGCAGAGAGTGACCTGTGGAGAAAGATGGAGTGATTTTTACTGCGAAAATTTCAATCCACACTCTCCTCGCAGAGAGTGACAAATGCAAAGGACAGCTTTTATGCTGTTACTCCAATTTCAATCCACACTCTCCTCGCAGAGAGTGACGCTTGATGGCAAAATTGATGGGGCGTATATAGAAATTTCAATCCACACTCTCCTCGCAGAGAGTGACCGCAATGTCTGTAGTCCGGGCAATTACATCTATAATTTCAATCCACACTCTCCTCGCAGAGAGTGACCAATAGACCTTCTCCTACGGCGTAGGACAGCATAATTTCAATCCACACTCTCCTCGCAGAGAGTGACTGTTGTACCTTTAATTCAACATACCTGTCATCAATTTCAATCCACACTCTCCTCGCAGAGAGTGACTCTCCTCATGACAGATTGTAAGCCCGGCATTCTGATTTCAATCCACACTCTCCTCGCAGAGAGTGACTATTGCATTTGCTAGAAAAATCAGAAAATAAGGATTTCAATCCACACTCTCCTCGCAGAGAGTGAC

>CP035945|12|4|5392187-5394093|PILER-CR
ATTTCGATCCACACTCTCCTCGCAGAGAGTGAC	GTACCGTTGTAATGCCTGATTTTGTGATCCAGA
ATTTCAATCCACACTCTCCTCTCAGAGAGTGAC	TTTCTTCTCTATCAGTCCCACATCAGCCAATTCT
ATTTCAATCCACACTCTCATCGCAGAGAGTGAC	CATCCGTCTACTATAGCATTTAGCGGAGATTTAAA
ATTTCAATCCACACTTTCCTCACAGAGAGTGAC	GATAGTGCAAGAGTAAACAAGAAAAGCGTATCCTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GGCAAGGATTATCTGTATATCCCCGAGGCCGTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AACGATTGAGAGGTGGTGAGGCTTGGCAAGACCGA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AGAGCATACAGAGAGAGGATGGCAACCATAATG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GAGACGAAACGGTCAGACCGAAACGGATAATAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCCTCCGGTCCAGATCTTGCCACCGTCTTTAGACCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TTATGCGCTGGTGCTCGGCTTCTGCACCTAACAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATATGGATTCATCCCCAGGATTGCTGATGCGTCG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AGCAAAAGAACGCGTCATCCGAAACTCACAGGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TTACACCTTCCTGGTTTATATATGATCCGATCT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCATAGAATCTATGCTTTTATTAAAATGGGAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CGGACTGTCTCGACGAAATGCAAAATTTGATAGCG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TGGAAAATTTAAAATACCAGACGATACACTCTT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GAAGCTATTGAGATGACACCAGTTGAACTGAAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATCATAGGCAAGTGTCAGGCCACAATTTATAAT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCAAAAGCCTCCATCAAATATGCATCGTCAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCAAAAGCCTCCATCAAATATGCATCGTCAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CTGTGGAGAAAGATGGAGTGATTTTTACTGCGAAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AAATGCAAAGGACAGCTTTTATGCTGTTACTCCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCTTGATGGCAAAATTGATGGGGCGTATATAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CGCAATGTCTGTAGTCCGGGCAATTACATCTATA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CAATAGACCTTCTCCTACGGCGTAGGACAGCATA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TGTTGTACCTTTAATTCAACATACCTGTCATCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCTCCTCATGACAGATTGTAAGCCCGGCATTCTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATTGCATTTGCTAGAAAAATCAGAAAATAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC

>CP035945|12|11|5392187-5394093|CRISPRCasFinder
ATTTCGATCCACACTCTCCTCGCAGAGAGTGAC	GTACCGTTGTAATGCCTGATTTTGTGATCCAGA
ATTTCAATCCACACTCTCCTCTCAGAGAGTGAC	TTTCTTCTCTATCAGTCCCACATCAGCCAATTCT
ATTTCAATCCACACTCTCATCGCAGAGAGTGAC	CATCCGTCTACTATAGCATTTAGCGGAGATTTAAA
ATTTCAATCCACACTTTCCTCACAGAGAGTGAC	GATAGTGCAAGAGTAAACAAGAAAAGCGTATCCTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GGCAAGGATTATCTGTATATCCCCGAGGCCGTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AACGATTGAGAGGTGGTGAGGCTTGGCAAGACCGA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AGAGCATACAGAGAGAGGATGGCAACCATAATG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GAGACGAAACGGTCAGACCGAAACGGATAATAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCCTCCGGTCCAGATCTTGCCACCGTCTTTAGACCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TTATGCGCTGGTGCTCGGCTTCTGCACCTAACAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATATGGATTCATCCCCAGGATTGCTGATGCGTCG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AGCAAAAGAACGCGTCATCCGAAACTCACAGGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TTACACCTTCCTGGTTTATATATGATCCGATCT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCATAGAATCTATGCTTTTATTAAAATGGGAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CGGACTGTCTCGACGAAATGCAAAATTTGATAGCG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TGGAAAATTTAAAATACCAGACGATACACTCTT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GAAGCTATTGAGATGACACCAGTTGAACTGAAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATCATAGGCAAGTGTCAGGCCACAATTTATAAT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCAAAAGCCTCCATCAAATATGCATCGTCAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCAAAAGCCTCCATCAAATATGCATCGTCAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CTGTGGAGAAAGATGGAGTGATTTTTACTGCGAAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AAATGCAAAGGACAGCTTTTATGCTGTTACTCCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCTTGATGGCAAAATTGATGGGGCGTATATAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CGCAATGTCTGTAGTCCGGGCAATTACATCTATA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CAATAGACCTTCTCCTACGGCGTAGGACAGCATA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TGTTGTACCTTTAATTCAACATACCTGTCATCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCTCCTCATGACAGATTGTAAGCCCGGCATTCTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATTGCATTTGCTAGAAAAATCAGAAAATAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC

>CP035945|12|5|5392187-5394093|CRT
ATTTCGATCCACACTCTCCTCGCAGAGAGTGAC	GTACCGTTGTAATGCCTGATTTTGTGATCCAGA
ATTTCAATCCACACTCTCCTCTCAGAGAGTGAC	TTTCTTCTCTATCAGTCCCACATCAGCCAATTCT
ATTTCAATCCACACTCTCATCGCAGAGAGTGAC	CATCCGTCTACTATAGCATTTAGCGGAGATTTAAA
ATTTCAATCCACACTTTCCTCACAGAGAGTGAC	GATAGTGCAAGAGTAAACAAGAAAAGCGTATCCTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GGCAAGGATTATCTGTATATCCCCGAGGCCGTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AACGATTGAGAGGTGGTGAGGCTTGGCAAGACCGA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AGAGCATACAGAGAGAGGATGGCAACCATAATG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GAGACGAAACGGTCAGACCGAAACGGATAATAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCCTCCGGTCCAGATCTTGCCACCGTCTTTAGACCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TTATGCGCTGGTGCTCGGCTTCTGCACCTAACAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATATGGATTCATCCCCAGGATTGCTGATGCGTCG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AGCAAAAGAACGCGTCATCCGAAACTCACAGGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TTACACCTTCCTGGTTTATATATGATCCGATCT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCATAGAATCTATGCTTTTATTAAAATGGGAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CGGACTGTCTCGACGAAATGCAAAATTTGATAGCG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TGGAAAATTTAAAATACCAGACGATACACTCTT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GAAGCTATTGAGATGACACCAGTTGAACTGAAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATCATAGGCAAGTGTCAGGCCACAATTTATAAT
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCAAAAGCCTCCATCAAATATGCATCGTCAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCAAAAGCCTCCATCAAATATGCATCGTCAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CTGTGGAGAAAGATGGAGTGATTTTTACTGCGAAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	AAATGCAAAGGACAGCTTTTATGCTGTTACTCCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	GCTTGATGGCAAAATTGATGGGGCGTATATAGAA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CGCAATGTCTGTAGTCCGGGCAATTACATCTATA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	CAATAGACCTTCTCCTACGGCGTAGGACAGCATA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TGTTGTACCTTTAATTCAACATACCTGTCATCA
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TCTCCTCATGACAGATTGTAAGCCCGGCATTCTG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC	TATTGCATTTGCTAGAAAAATCAGAAAATAAGG
ATTTCAATCCACACTCTCCTCGCAGAGAGTGAC

Protein	Signature genes	Signature genes Name	Protein_function
CP035945.1\|QBE99238.1\|5408723_5410019_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226206
CP035945.1\|QBE99237.1\|5407349_5408711_-\|Putative-dipeptidase	unknown	unknown	gnl\|CDD\|349884
CP035945.1\|QBE99226.1\|5377815_5378628_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211589
CP035945.1\|QBE99225.1\|5377116_5377785_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224204
CP035945.1\|QBE99224.1\|5376177_5376969_-\|Ferredoxin	unknown	unknown	gnl\|CDD\|380319
CP035945.1\|QBE99239.1\|5410032_5411532_-\|putative-response-regulatory-protein	unknown	unknown	gnl\|CDD\|381091
CP035945.1\|QBE99228.1\|5379516_5380194_-\|Phosphatidylcholine-synthase	unknown	unknown	gnl\|CDD\|224104
CP035945.1\|QBE99233.1\|5394446_5402018_-\|Beta-L-arabinobiosidase	unknown	unknown	gnl\|CDD\|350146
CP035945.1\|QBE99227.1\|5378624_5379497_-\|Phosphatidylserine-decarboxylase-proenzyme	unknown	unknown	gnl\|CDD\|179097
CP035945.1\|QBE99234.1\|5402164_5403391_-\|Melibiose-operon-regulatory-protein	unknown	unknown	gnl\|CDD\|274977
CP035945.1\|QBE99230.1\|5381289_5382003_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239481
CP035945.1\|QBE99240.1\|5411648_5412488_-\|L-arabinose-transport-system-permease-protein-AraQ	unknown	unknown	gnl\|CDD\|223472
CP035945.1\|QBE99236.1\|5406368_5407286_-\|Oxidoreductase-YdhF	unknown	unknown	gnl\|CDD\|381318
CP035945.1\|QBE99229.1\|5380255_5381293_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377103
CP035945.1\|QBE99232.1\|5390641_5391679_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|380511
CP035945.1\|QBE99241.1\|5412484_5413372_-\|Inner-membrane-ABC-transporter-permease-protein-YcjO	unknown	unknown	gnl\|CDD\|224096
CP035945.1\|QBE99235.1\|5403527_5406152_-\|Pyruvate,-phosphate-dikinase	unknown	unknown	gnl\|CDD\|236446
CP035945.1\|QBE99242.1\|5413447_5414767_-\|Multiple-sugar-binding-protein	unknown	unknown	gnl\|CDD\|270303
CP035945.1\|QBE99231.1\|5382244_5390137_-\|Beta-L-arabinobiosidase	unknown	unknown	gnl\|CDD\|379155
CP035945.1\|QBE99223.1\|5375207_5376155_-\|hypothetical-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253

Protein	Function_ID	Function_description	E-value
CP035945.1\|QBE99238.1\|5408723_5410019_-\|hypothetical-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	2.9303e-108
CP035945.1\|QBE99237.1\|5407349_5408711_-\|Putative-dipeptidase	gnl\|CDD\|349884	cd03888, M20_PepV, M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides. Peptidase M20 family, Peptidase V (Xaa-His dipeptidase; PepV g.p. (Lactobacillus lactis); X-His dipeptidase; beta-Ala-His dipeptidase; carnosinase) subfamily. The PepV group of proteins is widely distributed in lactic acid bacteria. PepV, along with PepT, functions at the end of the proteolytic processing system. PepV is a monomeric metalloenzyme that preferentially degrades hydrophobic dipeptides. The Streptococcus gordonii PepV gene is homologous to the PepV gene family from Lactobacillus and Lactococcus spp. PepV recognizes and fixes the dipeptide backbone, while the side chains are not specifically probed and can vary, rendering it a nonspecific dipeptidase. It has been shown that Lactococcus lactis subspecies lactis (L9) PepV does not hydrolyze dipeptides containing Pro or D-amino acids at the C-terminus, while PepV from Lactobaccilus has been shown to have L-carnosine hydrolyzing activity. The mammalian PepV also acts on anserine and homocarnosine (but not on homoanserine), and to a lesser extent on some other aminoacyl-L-histidine dipeptides. Also included is the Staphylococcus aureus metallopeptidase, Sapep, a Mn(2+)-dependent dipeptidase where large interdomain movements could potentially regulate the activity of this enzyme.	4.4938e-127
CP035945.1\|QBE99226.1\|5377815_5378628_-\|hypothetical-protein	gnl\|CDD\|211589	TIGR00588, Includes:_DNA-apurinic_or_apyrimidinic_site_lyase, 8-oxoguanine DNA-glycosylase (ogg). All proteins in this family for which functions are known are 8-oxo-guanaine DNA glycosylases that function in base excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). This family is distantly realted to the Nth-MutY superfamily. [DNA metabolism, DNA replication, recombination, and repair].	1.95622e-47
CP035945.1\|QBE99225.1\|5377116_5377785_+\|hypothetical-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	6.40098e-58
CP035945.1\|QBE99224.1\|5376177_5376969_-\|Ferredoxin	gnl\|CDD\|380319	cd02143, nitroreductase_FeS-like, nitroreductases with an N-terminal iron-sulfur cluster-binding domain. Members of this family utilize FMN as a cofactor. This family may be involved in the reduction of flavin or nitroaromatic compounds via an obligatory two-electron transfer. Nitroreductase is homodimer. Each subunit contains one FMN molecule.	1.88992e-42
CP035945.1\|QBE99239.1\|5410032_5411532_-\|putative-response-regulatory-protein	gnl\|CDD\|381091	cd17536, REC_YesN-like, phosphoacceptor receiver (REC) domain of YesN and related helix-turn-helix containing response regulators. This family is composed of uncharacterized response regulators that contain a REC domain and a AraC family helix-turn-helix (HTH) DNA-binding output domain, including Bacillus subtilis uncharacterized transcriptional regulatory protein YesN and Staphylococcus aureus uncharacterized response regulatory protein SAR0214. YesN is a member of the two-component regulatory system YesM/YesN and SAR0214 is a member of the probable two-component regulatory system SAR0215/SAR0214. Also included in this family is the AlgR-like group of LytTR/AlgR family response, which includes Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR and Bacillus subtilis sensory transduction protein LytT, among others. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.55816e-49
CP035945.1\|QBE99228.1\|5379516_5380194_-\|Phosphatidylcholine-synthase	gnl\|CDD\|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	2.3514e-33
CP035945.1\|QBE99233.1\|5394446_5402018_-\|Beta-L-arabinobiosidase	gnl\|CDD\|350146	cd18825, GH43_CtGH43-like, Glycosyl hydrolase family 43 protein similar to Clostridium thermocellum exo-beta-1,3-galactanase CtGH43 and Ruminococcus champanellensis arabinanase Ara43A. This uncharacterized glycosyl hydrolase family 43 (GH43) subgroup belongs to a subgroup which includes characterized enzymes with exo-beta-1,3-galactanase (EC 3.2.1.145, also known as galactan 1,3-beta-galactosidase) activity such as Clostridium thermocellum (Ct1,3Gal43A or CtGH43) and Phanerochaete chrysosporium 1,3Gal43A (Pc1, 3Gal43A), and arabinanase (EC 3.2.1.99) activity such as Ruminococcus champanellensis Ara43A. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	1.22026e-134
CP035945.1\|QBE99227.1\|5378624_5379497_-\|Phosphatidylserine-decarboxylase-proenzyme	gnl\|CDD\|179097	PRK00723, PRK00723, phosphatidylserine decarboxylase; Provisional.	1.63592e-92
CP035945.1\|QBE99234.1\|5402164_5403391_-\|Melibiose-operon-regulatory-protein	gnl\|CDD\|274977	TIGR04094, AraC_family_transcriptional_regulator, YSIRK-targeted surface antigen transcriptional regulator. Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.	7.94857e-30
CP035945.1\|QBE99230.1\|5381289_5382003_-\|hypothetical-protein	gnl\|CDD\|239481	cd03386, PAP2_Aur1_like, PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.	2.88335e-13
CP035945.1\|QBE99240.1\|5411648_5412488_-\|L-arabinose-transport-system-permease-protein-AraQ	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.52366e-64
CP035945.1\|QBE99236.1\|5406368_5407286_-\|Oxidoreductase-YdhF	gnl\|CDD\|381318	cd19092, AKR_BsYcsN_EcYdhF-like, Bacillus subtilis YcsN, Escherichia coli YdhF and similar proteins. Bacillus subtilis YcsN and Escherichia coli YdhF are prototypes of this family. They are uncharacterized aldo/keto reductase family oxidoreductases.	6.59063e-147
CP035945.1\|QBE99229.1\|5380255_5381293_-\|hypothetical-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	1.06569e-27
CP035945.1\|QBE99232.1\|5390641_5391679_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|380511	cd06288, PBP1_sucrose_transcription_regulator, ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	9.90935e-103
CP035945.1\|QBE99241.1\|5412484_5413372_-\|Inner-membrane-ABC-transporter-permease-protein-YcjO	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.00572e-69
CP035945.1\|QBE99235.1\|5403527_5406152_-\|Pyruvate,-phosphate-dikinase	gnl\|CDD\|236446	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional.	0
CP035945.1\|QBE99242.1\|5413447_5414767_-\|Multiple-sugar-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.81519e-35
CP035945.1\|QBE99231.1\|5382244_5390137_-\|Beta-L-arabinobiosidase	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	1.00718e-09
CP035945.1\|QBE99223.1\|5375207_5376155_-\|hypothetical-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.98364e-53

>CP035945.1|QBE99232.1|5390641_5391679_-|HTH-type-transcriptional-repressor-PurR
MATIKEIAKACNVSISTVSNILNGKEKARQETKELVLQKAKEMNYVPNYMAKNLKQKNTKTIGIIAEDLTIFHTPTIVDGISACLEKKGYTLLMGNMRMYQKYGNAFYTFKEYSGLVQEEIQEMLAKRVEGIIYVEGHYHVMDHIPELFAVPTVAVYGKVDSREVPSVIYDDEQGGYEAAKALISMGHRKIGVITGSRQSFHTIERMRGFMKALFDHEIPFNPCWEINGEWNREDGYAGAEQLVRQGVTAIFSMNDIMAGGIYDYINEKGMRIGKDLSVIGFDDREISEAFYPTLSTVALPLNHMGSIAAELLTERLEGKKGSGEKKEYKIPCQVINRNSICKIK
>CP035945.1|QBE99231.1|5382244_5390137_-|Beta-L-arabinobiosidase
MKKKQNALSGLSFVLTAAMALGTCLPYLGPIEIKAAAKEFIAEKTDKGYHLRNEYFDVETGEYGEITSLKIVGDEYDTNYVMNVSDNPKQDTSAHEWMGDLMFKTKKSGEENWTEALTNSSDAGRSVELKDNKIVVTYDNTKTEGERAIRDFKLVETYSLTDDQLRWEITVENTTDTDLIFGDFGVPLAFHEIWVNQGEAYEACTVDHSFVGKDSSYVYATRPSGDGHFLLMTPDTETGAGFEYQDHWQIGQRRAEEKEWCMDQADWANGLNVFYIHSDAISADEKSGNKGYMESSSMTLESGKSKTYAFEFTGVADEAEMKDTLYEEGIMDAVAVPGMTFSRDMPAKMYLHTKAAAEDISFEFRCPHTNNLHQGANTVSNNLSCERTEDNTYAEFAETKIIDGEQYHIYNIAFGDLGQNDIIVNYRQNGEDKTTMLQFYMMDDLQSALDLHSDFLLKTQWDAPGAIQDKVFDDWMMDSKSKRGSFDGYWGWGDDWGYVHGEYLAEMNSYNPVEEQVQALDEYLDTAIWQNLMQEHQEDFLIHDFLMPEPNSTPTYRGFAYPHIYNTYFSMYKIAEQYPDLIAYKEDADTYLLRCYHIMDALYNEGSVGYNWNTGLMGESTTPSIIQALKERGYEEEAENLESVMEEKFNNFANDKYPYISEYPYDNTSEEAVYTMAKMFGNEEVMAKVNEKTRACRGVQPIWYHYGNPTTICGENWFNFQYTASLAGYCMDDWLRKQDNGMSSEEAGLAQRINYAGKLANFTVINSGQIDADPENVGTAAWTYQSEMGNDEALGTGGGKLHNGWRQMSGEADLALFGAIRIASADVATDPVFGLLGYGCEVSEKGSSYEVTPLDGVYHRLNLINEQISLELYRDQYSSAVVSKDGSSISMDVVNVTGQEHESNLDITGIPSGNYQVLVDGRTAGSFEAQGKTTTVALPLPKCESAHIEIRPGALLDNTTPVVDAGEDAEVSMDDETVLHGTARDAAWLHRIPDVKWTAEESPAGAKVNFANEEAVSTKVEFDKAGEYILKLTAKGRSSTVSDTVKITVEGTPQLPEILALYDFEEENVDIENKTVKDVSGSGIDAELKSNAEFSEGKEGRGISMDGEVGGYVKLKNGLTKYTKEATISMDVKLNGKQTNGTRLFEFGDMDENLFYVACESANELSLNITNQKTKETVTAKSGVLLNPDTWQNAEVTLKDNKAVLYINGEAYAEIENAEFDFSRLGTAQRSFLGRSHSESTPWLNGSYDNFKMLSKAMTAEEIREAYGSDEETVVTGVVVSPVITSVGVAPEMPKTAKVEYSSGLCQYETVTWDEIDKSSYAKKGEFEAAGKIEALELEVSTKVQVVEGKEQNIALIATPTAIFNNPEDLGGVAGLNDGFDPANSNDKSHGVWHNWQGDQKGEAWVQYTWNSEVTITGTDAYYFTDGNFAPASVNFQYLDREGNWRDVENGDGYGTKLNQYNKTSFSPVMTTAFRMIMNPKTLGCGVIEWKVYGYSDESAADKKLLQAALDKAKVLNMDLFEEGAEEILNAAITEAQAVYDNTEAAQDEVDAAAARLERVMITLPSKDGNLAYSAAPSTSYVSDWEKLSAVNDAVIPDNSQNPDKTLFPRYGTWGNTSEYETVTYTWNTDVTLKGSDIYFWYDGSETTNGGINIPKSYQYEYLDSEGNWCEVTNPSAYETEIDGFNTTEFDAVTTTAFRVTMAKQANDNNGIGLMEWKVYGTMAKADKNALTEAVEEASGIDTEIYTQETRTAFEKALADAKALLADPDVSGEEVKIALSRLVKAQNNLEEKGEEGVRNLALGAKADGLCNYDGLDGRINDLGGLAALNDGVLPENSADQSGPVWHNWHDRYGSENEILNGWVSYVWDEPVVLDSTSVYYFQNGNGDFLPKAAEFEYLDEDGNWKSVTGAEGLGCEADRFNTTNFDRITTTAIRMTMEPACREDNQEDPSRGTGVLEWQVMGIYASELPSKDVLEAAVKAAEGKQEADYTEDSWKAFAQALERAKKVLDEAYADQEQINAALDSLMEAMENLTEAGSEAGVRNMAAYAAADGLCNYDGQDGRPYDLGGLAALNDGVVPANSGDTSNGVWHNWLNRYDDNGSILDGWVSYTWDKPVVLDEISAYFFQNESGDFLPSSAEMEYLQEDGTWVPVSENGIGCSADTFNTITFEKITTTSIRMTMKAALREGSEEDPSRGTGVIEWQAMGQYAEEIKDTAEKTLLGEALAEAAEKQEEEYTKTSWEDFQKAYKKAKEIYTDTHADQLQVDEALAELKEAMSNLTKRADLTQLNSLIAQAEKKEESAYTEESWKPFAEALTAAREAAEKDDITQESADSAKNALESALKNLVRKDAAQVKKEALKAAIEEAEKREESKYTKESWEGFARALKAAREIFENESAAAEQVEEQTALLNAAMAALVPREKDPESPDSEADKAALSKLVEKANTLTRADYTQDTWAVFDQALVNAQKVLADGSADQETVDTAQKDLQAAMEQLVKVSSENGLDLDKIKTLIEKGEKLEKGDYTAASWKTFSQALKEAKAILDAEGASQSDVDKKAQALEKAMENLKKKSGSGSQGKTSGNGSSGKGGGSGSGSSAKSVKTGDETPILLFAGLAVLSFAGIVILRKKRRTE
>CP035945.1|QBE99230.1|5381289_5382003_-|hypothetical-protein
MQNKQKKNAWIPSYAVFPLLSCVTVNCIVYFGISKIANEWKHYDLTLPFDRAVPLVPGFVSIYLGCYLFWIINYILIARQGEEHCIRFAAADIMSRLVCCAFFLLLPTTNVRPVLSGEGIWVTLLQAVYKADAPVNLFPSIHCLVSWFCFIGIRGRKSVPKAYRIFSCLFALLVCVSTQVTKQHYIVDVFGGIAIAELTYYIAFHTSIYKLFKRLFDRLYEIFFSRRKSTCGKESEV
>CP035945.1|QBE99229.1|5380255_5381293_-|hypothetical-protein
MTSKKKKIGNGIFLAAVFILTIYSVFHGEDLGAVLKAIVRVNPWYLLPAVLGVIIFIWGESIIIHYMLGTLNIRTKKRTCFQYSCIGFFFSCITPSASGGQPMQIYYMRKNKISVPVATLVLMIVTITYKSVLVFIGLFVAFFQRGFVHKYLEGILPVFYLGVALNVFCCIAMSVLVLCPSLAKFIMMKGLSVLEHVRIFRKKEERTRKLEESMNHYTATSDYLKGHGKVIVNVLLITFLQRFALFFVTWFVYRAFGLHGASVYDVVMLQAVVSVSVDMLPLPGGMGISENLFLIIFKTIFAGSLLLPAMVLSRGIAFYVQLLFSAGMTAVAHFTIGRKAQDSTA
>CP035945.1|QBE99228.1|5379516_5380194_-|Phosphatidylcholine-synthase
MIGFYNYSVILTYISLLSSVFGMTQAIHGRFKAAVFCLALSGLCDMFDGKIARSMKNRTEDEKSFGIQIDSLCDVVCFGVFPAMICYLLGVRGPIGLAVIALYCVNSVIRLAYFNVMEMKGALVSEEGEKYYKGLPITSMAVVLPLVFMIQFFVSDFAFIVCLHLALLVVGILFVVNFRFRKPKNSTLAVLVAVVAVALCIMLLRTRYRIEFRHGWPWLPWLRKL
>CP035945.1|QBE99227.1|5378624_5379497_-|Phosphatidylserine-decarboxylase-proenzyme
MKYIDREGNITTEDSGQDRFLRWMYNHRTGRMALKILVQPVVSKAGGWLLDSRCSRVLIKPFVKRQGISLDLYERKEYASYNDFFTRQIKKEYRPAEGDADTLISPCDGKLSVYPIDGKRRFSIKGTEYTVDSLLRSGHMARRYQGGYACIFRLTVDDYHRYCYVDNGRKSMNIRIPGVFHTVNPAANEVCPIYKENTREFSLLQSEHFKVVLMMEVGALLVGRITNYHEEETVKKGEEKGRFEFGGSTVILLFQKDAVKFDQRFLYNTENGYETIVKMGERLGEAADKE
>CP035945.1|QBE99226.1|5377815_5378628_-|hypothetical-protein
MTKRKIADLDLGQIAASGQCFRMVQKRENVYALTAFGKYLEIEQKGDVFSFSCTEKEFGKIWEDYLDLHTDYGAIKRSVDEEDAYLTEAVQKGWGIRILRQDLWEMIVTFLVSQNNNISRIRKSIELLCSTIGEEKHTGEGVRYHTFPEPEAIVNAGMEVLSGLGLGYRDKYIFSTAQSVLDGSLDLNMLQAADYETAHRELVRQYGIGKKVADCICLFGLYHIDAFPVDTHVKKILEAHYPEGFPYDRYKGCAGILQQYMFYHDLNAAA
>CP035945.1|QBE99225.1|5377116_5377785_+|hypothetical-protein
MDLVFLYLEYPLRMLGAIFCGALIGYERENQMKMAGIRTHSIVSLASALMMIVSKYGFFDVLSSHVNLDPSRIAAGVVTAIGFLGAGVIFTHKMNISGLTTSAGLWATVGVGMALGAGMYVPGISATVLILLLQFFFHRNFRWLKSSSIEQVTLIMEQEDNLRSILENTFHLDEIKITSMKVKRLKDNQVEVKLFVKFPDSYDIFHTLDLLRKNPKITSIDL
>CP035945.1|QBE99224.1|5376177_5376969_-|Ferredoxin
MAVINQEICVGCGACVKDCPGSAIRQKEGKAEVTRSCIQCGHCVAVCPVNAASIPEFDMEDVEEYREEDFSISPEHFLRAVKYRRSIRDFKEEIPGREVIERILEAGRYTATAKNMQDCTFVVVRERLSEFKNLVWQEMPDIIRSLKETGPDYAGAFSYFYKLWQGDKERDTFFFNTPVFLVIASKNQLDGGLAAANIENMAVAEGLGALYSGYMMRVIRESPVLQEWLGIGEKAVSCCMLLGYPNVVYRRTAPRKKADVLWK
>CP035945.1|QBE99223.1|5375207_5376155_-|hypothetical-protein
MKIDRLIGILSILLQQDKVTAPYLAEKFEVSRRTINRDVEDICKAGIPIVTTQGQNGGISIMEGYRLDKTLLTSRDMHSILAGLRSLDSVAGTNRYQLLMEKLSVGSQEVLTSNDHIRIDLSSWYKSALAPKIELIQNAIEDCRLIAFRYYSPKGEGEREIEPYLLVFQWASWYVWGYCRERQDYRMFKLNRMDSLKDTGVLFEKRQLPDCDCSPRRIYPASIHVKVRCAPQMKWRLIEEYGVECFEEQEDGYLLFVSDFADRNSLFGWLLSFGEQMELLEPVKLREELWELLGRMQRCYMKETDFPGNDDRQLS
>CP035945.1|QBE99233.1|5394446_5402018_-|Beta-L-arabinobiosidase
MKGFKRGIAAATTAALCLTSIPMNGLCLVSAAEPDRTVKLQPGLASTFHDTNEDGLGEFEGWGTSLCWWANRIGYSDAMTEKAAEVFFSDKGLDMNIGRYNVGGGDHVGVPTEVPVNEKALFYDLETEGYKPQYSGSKMAVSENSAMKDLQYTVSDADFGITKGNKVGTFKSIGWINKLGDTPGDGDNLRYTVNAKEEGKYTVKLLLTLTGSNKRDVAVRVNDSEDHIVDADTINKNLIASGNNNLLFLVTIPDVNLNAGENTLNIAGKNDWTLDFVKMAVIKSGEEGTLPEGEEYLHSPHITRSDSAVPGYAVDVTKIDTSKHELSWYKDNFDRADEECGYAWKYNWDADVNQLNILKAAAEASGEDFIAEAFSNSPPYFMTNSGCSSGAVDANKDNLRSDSYHAFAAYMADVIEHWNDEGVITFQSTTPMNEPYTSYWGAYSNKQEGCHFDQGESQSKIIEALNEELEKKEIDIIISGTDETSIDTAITSYNALSDEAKNIIQRIDTHTYGGSKRSELKALAEDQEKNLWMSEVDGAYTAGTNAGEMSAALGMAKAMMQDVNGLNANAWILWNAIDMHVDKEIKTSSDADYASLDELYSRVDMNSGYWGIAIGDHDNEDILLTKKYYAYGQLSRYIRPGYTIIGSSADTLAAYDPEGGKVVVAAVNTSGEDKTWKFDLSSFSTMGDNVTAIRTSGSLKDGENWADVSSDGDIIADTAKKSITATLKANSITTYIVDGVTYDSTAEEIIKIEDVNVYTIEDIPAVLPETVQTVTNKNNTMEKKVTWNLEGVDLTQSGDVTGTVEGTTLTATAKVQVVAPNMIYFIDCNSPESPKYAAMDQYADLLNEKADQAYTEGSWGYLDAYGKYNGDVKDEYDTGWYANSGQTIKYTVPLDAGNYNVTFGFKEWWRDSNKSRKMTISATQESGTKELGSSNTWNGGNWWNSNTFELVCEETGDVTFSIEKQSGQPDPVLSFIQIQKVLDLDELKAALKAASEVERGLYPAAKLAVLDAAVEAGKALALKASTTQEELTDGAKAITDAIEALGTGYTEEEIAANDHVLYLVNCGTPDASVVPENYILGLYQSNVEQEYAADADTGLSWGYEPNDENSKIVNGGKNATDITESYIYMADTGITFVKDVSGFKYKFELPDRANSDYAVTLGFKNPWDTRNVDIKLEGETVESDLTLTKSQLIEKTYKTEVTDGELNVMVHSPKRTNQYGDPVLSYIIVKAVAAYTTDRITEVITSYQSAMEGHSYSESTKGAFDEAVQEAQELVDNGSTDQKAIKNALIKLEETYNALKEIYTYSSITGTNGAQMFDNNGNKIQAHGGQIQQFTIDGETKYYWYGEDKTNGYRPVVGVHLYTSSDLYNWTDEGVVLRSIPVSEEDYGKDQTDGYKADLSIFETDEYFKNLYGEYAGQDPDDTDNYSSKLEEVYWNLAEDRTVIERPKVLYNDATGKYVMWFHADGRTPTSSADYGKARAGIAISDSPTGPFKLLGTYKLHDSKDANHSWDNVGGAVRDMNLFKDEDGQGYVIYSSDGNLTTYIAKLNDSYTGLIADPKEAVEGTGKDAEELRASDYTRNFIDASREAPAMFKYKGKYYIVNSGCTGWAPNKAQYAVADHPLGPWTVMGDPCVGDTKGTTFDTQSTCVFPVDAEKGKFIYMGDRWYNPDTGGDLSDSRYVWLPVEFLPGDQIQLKDYADWTLEELENKASFEIVSGLPTVVSSVSEIQDVLPSTVVVDFGSTTAEMDVTWDVGTLAEDKLGIAAVTGILTDGNRKFTHNISIVNPKLIYFFDSGADTSEYYDTVNANLLGRLRNGAPDGAYTEENGAGYTGVTQSQDKDNYDLGHRSGDNYLSNGWWAASGKNIEYAFDLEPGTYTVSAGFQEWWNTSRPSKMTIKSGDKTLKEKAFTVYNTSTDLQVNETFEVTEENAGRITVTVSKTGNPDPVLSWIAVTHDDASVNKDKLETLITAAGALKKENYSEATWAVLSSALDEAIKAAENEEDQKAVDEVVRALLAAMEGLESTADKDELQKLVDEVNEFDHSIYTAASWSEYEAVVGQAKTDAQRVLDDHAAIKEDVDAAIKALHTAFEDGKEKLVTIQSVLESGIAENRISESSKDSYTEESWADYQTALEAAEKLMGSNDEAAVNAAIEILAEARKALVEKPEHVVDKTELIEAIAEAPAEEDAGLYTAASWTPYAAALTEALTVCHNEQAGQLDVDSALAVLIQAQEKLVTLEDKLAGIIKKYSAGISSEETYTAESWSAYAKALAAAAELQGKDGLTEEEIDTAEAILAEAYRGLVPAEIITVHKEALKAVIEQTEQLKKEDYTEEAWTVFTEALSKAQGVYDNEESSQEEVNTAVSALTDAIAELKKHPAVTEEKTDKSALRALLEQASQLKKDDYTGTTWEKFQKAFDDASNINESDKATQEQIDTATAALKAAMDQLEKVAAGPNEKPKAPSDNKNNGTGGKKTNTPTSGGSQKGTSSAKTGDETPIGMFAGFGAVALIAIFACTLSILRKRKKYN
>CP035945.1|QBE99234.1|5402164_5403391_-|Melibiose-operon-regulatory-protein
MRQPFFLEHMVNLIHAPFYVFDDRKQMIQKFGGREIETILFEKNPELLQKAYSKKNEEHPVIFTDKVLVFAVFDRGMAEKSIMIAGPVTIGRLSQETLIQLRREYKLGRKSGYTPPVCPLDKFVSGVLLLHWHLTGQELTSAELWQKNQQYYTATLNIQNRISQDIFMRQENAGLHNPYEQELRELDSIEKGDTEALTRSISETYEGEIGILAKDPLRSHKNVAVGNITLASRAAIRGGISVEKSFSMADSFIQQVEEIDNVPEVEAFKRESQYFYARLVNEENTRGGEKQNVRANPLIGQVKDYIFNHLHDTIQVSDIAAYMQVNPDYLSHLFSSREKMTITNYIRQEKVRRGENLLKYSDYRVQEIAFYLGFCSQSHFARVFQQIVGMNPNEYRKKFGNRKKWKMK
>CP035945.1|QBE99235.1|5403527_5406152_-|Pyruvate,-phosphate-dikinase
MAKWVYLFSEGNANMRNLLGGKGANLAEMTNLGMPIPQGFTVTTEACTNYYDNGKKISEEIQGQIFEALTELEKIQGKKFGDNEDPLLVSVRSGARASMPGMMDTILNLGLNDIAVEGFAKKTGNARFAYDSYRRFIQMYSDVVMEVPKSFFEKIIDEVKEAKGVQYDTELTVDDLKDLVQRFKAIYSEEMNGEEFPQDPKEQLLGAVKAVFRSWDNPRAIVYRRMNDIPGDWGTAVNVQAMVFGNMGETSGTGVAFTRNPSTGEKGIYGEYLINAQGEDVVAGVRTPQPISKLAEDLPKCYRQFMELAMKLENHYRDMQDMEFTIQEGKLYFLQTRNGKRTAPAAIQIACDLVDEGMITPEEAVCRIEAKSLDQLLHPTFNAEALKAGEVIGSALPASPGAAAGKVYFTADDAKAAHEAGERVILVRLETSPEDIEGMHAAQGILTVRGGMTSHAAVVARGMGTCCVSGCGEIKINEEEKWFTLGGYTFKEGDYISLDGTSGKIYKGDILTEEASVGGNFGRIMRWADQFRKLQVRTNADTPVDTENAVKLGAEGIGLCRTEHMFFEPERIPKIRKMILSDNVEAREAALNELIPYQKADFKAMYKALRGRPMTVRYLDPPLHEFVPTDPEDIKALAEDMGLTVEEVQAKCDDLHEFNPMMGHRGCRLAVTYPEIAKMQTRAVIEAAIEVKEEMGYDIVPEIMIPLVGEKKELKFVKDVVVATAEEVMKEKGEYINYHVGTMIEIPRAALTADEIAEEAEFFSFGTNDLTQMTFGFSRDDAGKFLGSYYSNKIYESDPFAKLDQTGVGQLVQMAAEKGRKTNPTLKMGICGEHGGDPSSVEFCHKVGLNYVSCSPFRVPIARLAAAQAALNNK
>CP035945.1|QBE99236.1|5406368_5407286_-|Oxidoreductase-YdhF
MKKIEIGKGKISGSEIGLGCMRITGLPSVKEVRNLVDTAMDCGIDFFDHADIYAGGEAEQVFGQAIDPGIREKMIIQTKCAIRPGICYDFSKKHILESVDKSLARLQTDYIDILLLHRPDTLMEPEEVAAAFEELERSGKVRCFGVSNQNAMQIELLNQYCGGKILIDQLQFSIAHCDIIDSGINVNVHNDAGANRDGSVLEYCRLKGITIQAWSPFQYGMFEGVFLNCDKFPELNRLIDELAEKYQVTNNAVAVAWILRHPARIQTIVGSTSQERIRGICQASDVKLTREEWYALYMAAGKQLP
>CP035945.1|QBE99237.1|5407349_5408711_-|Putative-dipeptidase
METSAVDRELDAWLSEKENDMVEDIASLVEIPSISGGRKGSAPYGKACREVLLKILEIGQRYGFSCRSFQDKCAVIQYGTGRKTVGIWGHLDVVPEGNGWLYPPFACTRKGDILIGRGVQDNKGPVIAFLYAMRYLKEKGFVPVVTFQQILGCREELDMEDVTSYLKENPAPDLSFVTDCAFPVCYGEKGICRVELISERLDRNMILAGGSASNSIPAYASAEIRLADGGQKTIQTKGISGHAAFPMGAKNALGILAEKIADECTEACILSEREKAVLEFLKKACGEGFGRELNIDCEDHISGVLTASGTVVKAEGERIVLGMDIRYPVTAKAGEILEKLGNEAGKYGFSIRRYEDDPPSYVDKDTPLVTCLTEAYEEVMKDGKKPYVMGGGTYARKIPNAVGFGPGLDFNRKEAELPKGHGDCHSADEVQSVSSLKMAVRIYVKALQKLDKL
>CP035945.1|QBE99238.1|5408723_5410019_-|hypothetical-protein
MEENRRRFYQSLLHREIAPALGCTEPAAAALTAACAAKCLGCIPEEILVRTSQYILKNAMNVGIPGIGMTGLDIAVALGALSASPEKELMILSGISPEKKRQAKAMTEQGKVRIELASTEEKIYIEVQVRAGAETAKAITAEAHKNITYVEKNDRVCYRKERKIRKAEETAEEIYTVTLEEILDFSEHTALENLEFLREVIQINREIALEGISHKYGLQVGKNLMDGTENGLVGQDAANYAAAMTAAAADARMAGCEKPVMSAAGSGNQGLTATIPIAAVGEKLELGEEKILRALALSILLTVHTKHYLGRLSVLCGCSISSAMGVACGIVFMLGGTYAQMTWAINSMVADISGVVCDGAKPGCALKIATAVQSAVRAANMALNGSGADSHDGIVHVNAEKTLENLGILGNWGMKDTNSIILDLMLEKQKI
>CP035945.1|QBE99239.1|5410032_5411532_-|putative-response-regulatory-protein
MMKILIAEDEIYARKSMKKQIMELDFGREFHILEAQNGEQGLALFRQEEPDLVFTDIRMPKMDGLELLREIKREDPEAKVIMVSAYADFEYAKSAIKFGAEGYLLKPIEDVELEEFLMKFRQQSTRKKEHAMFSGKDIVTRFIAQSVQEEDAGKDLLAERMFGKVFWKYQVLVLWFAGRKYPDREEFMLWLHNIYGQEVWTAFRLIELEKDIWMMVMGADGQSRFRQKRIVQKLPKEGYECYLGISAECQEPGELKSALAQATAAAENRIYSDEHLLEYRELAKIKAVKYEMTEEQKNFLQIALERKSRDRIQSAFSEIFRDMGEKGRIHVDSLEIFLAQAALMIHQAAGRPIPRLRLIDFANMEEMKSRLLETALEYCACGPEVRSSKGEDIIRGMKEYAQKNYHMDISVRMLAEKVFFMNAAYLSHLFTEKTGISYSAYIRRLRVEKARELLERDAYSITDIASMVGYNDTSQFIRIFKQETGMTPRKFRCQSLKEN
>CP035945.1|QBE99240.1|5411648_5412488_-|L-arabinose-transport-system-permease-protein-AraQ
MKAKKEGMGWIILRNLLILMGLFLILFPLYLVVINSFKTLEEAGKDFFALPSGLNLHNFKELFQNNNYWIFAKNSLIISAVSVGLILILVPSVSYAIARNFNKKYYKGVYYYLLMGLFIPSQVIMLPVTKLMTNLNMLNRQGLILLYAAYSLTQGVFLFVNYIRGLPFEIEESAYMDGCNVFQTYLRIVLPLVKPMLATLLIMDLLWIWNDFMLPLLILNRSKDIWTLPLFQYNFKTEYSFNYTMAFTAYLMSMLPMLIVYCMGQKHIIKGLTAGSVKG
>CP035945.1|QBE99241.1|5412484_5413372_-|Inner-membrane-ABC-transporter-permease-protein-YcjO
MNTEWKKKGSGKWIYFSFTLIPVVLYSFFYVYSVVNGIRYSFTDWDGMSTTFNLVGFKNYISLFKNPNFWGSLKTTVCYSILLVAGVVTLSLALSLSLNSLKRFKTFTKSVFFVPAMIGGITIALIWDQLFYRVVPLVGQALGIGWLSQSLLMTGKTALPAVVFVHIWQAVALPTVIFVAGLQQIPDEQYESAKMDGATPFQRFRFVTFPYLVPTLTVNLVLMIKQGFTSFDFPFALTGGGPVRSTEVIGILIYNDAFKNMRFSMANAEACVLFLVVAVFSLTQLKLTSKGGVHE
>CP035945.1|QBE99242.1|5413447_5414767_-|Multiple-sugar-binding-protein
MKKKLAVLLCAAMAVSSLAGCSSGVKEPKDTQEENKKEDSQDKTEGKKDSGKDVLTLEFFQQKSEEAAQVGYQNIIDKFNEQNPDIKIEMNTVPDAPTVLTSRVASGDIPVIFTDFPTQLQFHQKVANGYVQDLSEQEFLGNVEQSALDMTKQEDGKYYALPFSRNYMGVWYNMKIFEENNLEVPKTWEEFTGVCDALKEKGVTPLGLHGKDPGRVGHTFQCCTVAFDPKGVETIEKTVAGESSIEGDEGFKLVAEKMLTLLDYSNEDALALSDMQCYENFANGQYAMCITGSYARGTIMIANPDLKLGVFPLPNDTRETTNTLSGIDAAVCISAKASEEEKAGAYRFLEFLAQPENAQLFCDAEGAPSCITGVVHKDEGVQPMLELISDGQVHDWMASTIDNNVVTDLYNVTQGFWSEKNVDNYLKQMDESIAITSAE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP035945_2	2.3\|1095422\|33\|CP035945\|CRISPRCasFinder,CRT,PILER-CR	1095422-1095454	33	NZ_CP042975	Klebsiella pneumoniae strain KPN55602 plasmid pK55602_1, complete sequence	199476-199508	6	0.818
CP035945_8	8.1\|2947894\|30\|CP035945\|CRISPRCasFinder	2947894-2947923	30	MG592548	Vibrio phage 1.182.O._10N.286.46.E1, partial genome	34650-34679	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MK088486	Klebsiella pneumoniae plasmid pHNHZ604-1, complete sequence	19567-19596	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP052170	Klebsiella pneumoniae strain F16KP0075 plasmid pF16KP0075-3, complete sequence	4838-4867	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX470734	Escherichia coli strain Ecoli14-55 plasmid pEC55-NDM4, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX674681	Escherichia coli strain AS-01 plasmid pNDM5_AS, complete sequence	5866-5895	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX470735	Escherichia coli strain Ecoli15-50 plasmid pEC50-NDM7, complete sequence	24350-24379	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX683284	Escherichia coli strain EcU443 plasmid pECSEV_02, complete sequence	42871-42900	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX833071	Escherichia coli strain AD-19R plasmid pAD-19R clone ST48, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY296103	Enterobacter cloacae strain 13E169 plasmid pHN84NDM, complete sequence	14482-14511	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY499797	Klebsiella pneumoniae strain TH02-34 plasmid pTH02-34, complete sequence	20978-21007	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY659388	Citrobacter freundii strain 145 plasmid pCr-145, complete sequence	25010-25039	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY659387	Citrobacter freundii strain 30 plasmid pCfr-30, complete sequence	25010-25039	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY978629	Cronobacter sakazakii strain 505108 plasmid p505108-NDM, complete sequence	25551-25580	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF072961	Citrobacter freundii strain P10159 plasmid pP10159-1, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY435936	Escherichia coli strain WCHEC005215 plasmid pNDM5_WCHEC0215, complete sequence	17528-17557	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MG228426	Escherichia coli strain BO15V plasmid pKP_BO_OXA-181, complete sequence	39237-39266	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KU934011	Serratia marcescens strain 427862 plasmid IncX-3, complete sequence	23443-23472	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX523903	Klebsiella pneumoniae strain Kpn-29144/15 plasmid pOXA-181_29144, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KU647721	Escherichia coli strain CQ02-121 plasmid pCQ02-121, complete sequence	20106-20135	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX960110	Escherichia coli strain CREC-TJ2 plasmid pCREC-TJ2-NDM, complete sequence	88414-88443	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KU167609	Escherichia coli strain QD29 plasmid pNDM-QD29, complete sequence	16330-16359	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX960109	Escherichia coli strain CREC-A6 plasmid pCREC-A6-NDM, complete sequence	16353-16382	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY041843	Escherichia coli strain ZHDC40 plasmid pZHDC40, complete sequence	10403-10432	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KU963389	Escherichia coli strain ECO37 plasmid ECO37P1, complete sequence	15949-15978	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KU314941	Klebsiella pneumoniae isolate KP04 plasmid pKP04NDM, complete sequence	25752-25781	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX094555	Escherichia coli strain ZHDC33 plasmid pZHDC33, complete sequence	5901-5930	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX214669	Escherichia coli strain KW53T plasmid pKW53T-NDM, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KM400601	Klebsiella pneumoniae strain Kp0003 plasmid pJEG027, complete sequence	16276-16305	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KT362706	Klebsiella pneumoniae strain ST512 plasmid p45-IncX3, complete sequence	25010-25039	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KP987216	Citrobacter freundii strain 112298 plasmid p112298-NDM, complete sequence	25207-25236	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KT824791	Escherichia coli strain 1929 plasmid pEc1929, complete sequence	16331-16360	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KP776609	Escherichia coli strain OM26 plasmid pOM26-1, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KU167608	Escherichia coli strain QD28 plasmid pNDM-QD28, complete sequence	16330-16359	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP043333	Proteus mirabilis strain CRPM10 plasmid pNDM-5, complete sequence	12440-12469	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP018435	Klebsiella pneumoniae strain MNCRE53 plasmid pMNCRE53_2, complete sequence	7255-7284	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP023194	Escherichia coli strain TUM18530 plasmid pMTY18530-4_lncX3, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP040399	Escherichia coli strain BA22372 plasmid pOXA181_22372, complete sequence	831-860	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034284	Klebsiella pneumoniae strain I72 plasmid p72_OXA181_X3, complete sequence	23056-23085	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MK088485	Escherichia coli plasmid pHN4109c, complete sequence	21546-21575	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP049352	Escherichia coli strain 3R plasmid p3R-4, complete sequence	12603-12632	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP012995	Klebsiella pneumoniae strain KpN06 plasmid pKpN06-NDM7, complete sequence	33151-33180	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041931	Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374D, complete sequence	32734-32763	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP029735	Citrobacter sp. CRE-46 strain AR_0157 plasmid unnamed7, complete sequence	37977-38006	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034965	Escherichia coli strain WCHEC020032 plasmid pNDM5_020032, complete sequence	22274-22303	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	KX023261	Escherichia coli plasmid pSCE516-2, complete sequence	16277-16306	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP011987	Klebsiella pneumoniae UHKPC07 plasmid pUHKPC07-74.026kb, complete sequence	45744-45773	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN175389	Klebsiella pneumoniae strain KP-13-8 plasmid pKP-13-8-NDM-5, complete sequence	19717-19746	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN092230	Escherichia coli plasmid pJN11NDM5, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN017707	Escherichia coli plasmid pCNUH-11, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041956	Escherichia coli strain EC2 plasmid pEC2_1, complete sequence	46663-46692	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041947	Klebsiella pneumoniae strain KP2 plasmid pKP2_1, complete sequence	19701-19730	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP011992	Klebsiella pneumoniae UHKPC33 plasmid pUHKPC33-43.380kb, complete sequence	15098-15127	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN200942	Escherichia coli strain E648 plasmid pE648NDM-5, complete sequence	17326-17355	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_019162	Klebsiella pneumoniae strain CRE380 plasmid pNDM-HN380, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP018423	Klebsiella pneumoniae strain MNCRE69 plasmid pMNCRE69_2, complete sequence	7255-7284	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP012990	Klebsiella pneumoniae strain KpN01 plasmid pKpN01-NDM7, complete sequence	24350-24379	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021836	Klebsiella pneumoniae strain AR_0120 plasmid tig00000583_pilon, complete sequence	15046-15075	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP010881	Escherichia coli strain MNCRE44 plasmid pMNCRE44_5, complete sequence	38018-38047	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034323	Klebsiella pneumoniae isolate KSH203 plasmid pKSH203-NDM, complete sequence	24862-24891	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021692	Escherichia coli strain AR_0151 plasmid tig00001251, complete sequence	30905-30934	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024833	Escherichia coli strain CREC-532 plasmid pCREC-532_3, complete sequence	14976-15005	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021534	Escherichia coli strain AR_0149 plasmid tig00000221, complete sequence	45221-45250	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021682	Escherichia coli strain AR_0162 plasmid tig00003144, complete sequence	42009-42038	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP019679	Escherichia coli strain GSH8M-2 plasmid pGSH8M-2-4, complete sequence	16330-16359	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	KY930325	Klebsiella pneumoniae plasmid pUCLAKPC2, complete sequence	34944-34973	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_020811	Klebsiella pneumoniae strain KPN5047 plasmid pKPN5047, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	KR822247	Escherichia coli strain E0083033-2 plasmid pEc2A, complete sequence	46868-46897	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024825	Escherichia coli strain CREC-591 plasmid pCREC-591_4, complete sequence	4860-4889	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP036179	Escherichia coli strain WCHEC025970 plasmid pNDM5_025970, complete sequence	35796-35825	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MG570092	Escherichia coli plasmid pSTIB_IncX3_OXA_181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_023914	Enterobacter cloacae strain CRE727 plasmid pNDM-HF727, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP009776	Klebsiella pneumoniae subsp. pneumoniae strain KPNIH32 plasmid pKPC-def, complete sequence	76183-76212	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP008799	Klebsiella pneumoniae subsp. pneumoniae KPNIH24 plasmid pKPN-819, complete sequence	47123-47152	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP048346	Escherichia coli strain 124 plasmid p124_B-OXA181, complete sequence	2111-2140	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP028705	Escherichia coli strain VH1 plasmid pVH1, complete sequence	5899-5928	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041053	Enterobacter hormaechei strain C126 plasmid pEnC126OXA181, complete sequence	43673-43702	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP020074	Klebsiella pneumoniae strain AR_0115 plasmid tig00000004, complete sequence	25931-25960	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP020111	Klebsiella pneumoniae strain AR_0098 plasmid tig00000003, complete sequence	40823-40852	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN178638	Kluyvera cryocrescens strain SCW13 plasmid pNDM1_SCW13, complete sequence	24518-24547	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP038280	Raoultella ornithinolytica strain WLK218 plasmid pWLK-NDM, complete sequence	45651-45680	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP012563	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-2, complete sequence	7223-7252	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP050158	Enterobacter cloacae plasmid Carbapenemase(NDM-1)_IncX3, complete sequence	34450-34479	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP035910	Klebsiella pneumoniae strain BA4656 plasmid pIncX3	33285-33314	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP023897	Escherichia coli strain FDAARGOS_433 plasmid unnamed4, complete sequence	29874-29903	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034133	Klebsiella quasipneumoniae strain G4584 plasmid pG4584_52.4Kb, complete sequence	24090-24119	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP050157	Escherichia coli plasmid Carbapenemase(NDM-5)_IncX3, complete sequence	9277-9306	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP050161	Escherichia coli plasmid Carbapenemase(NDM-1)_IncX3, complete sequence	10102-10131	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	KX507346	Escherichia coli plasmid pECNDM101, complete sequence	16333-16362	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_LR130550	Klebsiella pneumoniae strain KPC2 isolate KPC2 plasmid 3	1397-1426	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024806	Escherichia coli strain AMA1167 plasmid pAMA1167-OXA-181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN335922	Escherichia coli strain GD1-16 plasmid pNDM-T16, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP029386	Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074 plasmid pNDM6_040074, complete sequence	35655-35684	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	LC545851	Escherichia coli Ec-MW07 plasmid pEc-MW07_NDM DNA, complete sequence	831-860	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MT028409	Klebsiella pneumoniae strain BS407 plasmid pBS407-3, complete sequence	22352-22381	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN865121	Escherichia coli strain SCNJ06 plasmid pNDM5_SCNJ06, complete sequence	12867-12896	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP052507	Klebsiella pneumoniae strain B16KP0226 plasmid pB16KP0226-2, complete sequence	4838-4867	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_020552	Citrobacter freundii plasmid pYE315203, complete sequence	25757-25786	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	AP023227	Escherichia coli YJ3 plasmid pYJ3-NDM1 DNA, complete genome	6792-6821	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN227183	Klebsiella pneumoniae strain 709 plasmid pKP709-OXA181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_022740	Klebsiella pneumoniae strain MGR-K194 plasmid pNDM_MGR194, complete sequence	16330-16359	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP019073	Escherichia coli strain CRE1493 plasmid p1493-2, complete sequence	17869-17898	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP031884	Klebsiella pneumoniae strain WCHKP095845 plasmid pNDM1_095845, complete sequence	66201-66230	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP035125	Escherichia coli strain EC25 plasmid pEC25_NDM-7, complete sequence	5817-5846	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MK715437	Klebsiella pneumoniae subsp. pneumoniae strain SCNJ1 plasmid pNDM5-SCNJ1, complete sequence	15320-15349	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP054267	Klebsiella pneumoniae strain 39427 plasmid pKPN39427.3, complete sequence	3802-3831	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP028718	Klebsiella pneumoniae strain SCM96 plasmid pSCM96-2, complete sequence	3192-3221	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP032889	Escherichia coli strain SCEC020022 plasmid pNDM5_020022, complete sequence	22273-22302	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018837	Escherichia coli strain M517 plasmid pM517-OXA181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018838	Escherichia coli strain M518 plasmid pM518-OXA181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018831	Enterobacter hormaechei subsp. xiangfangensis strain M206 plasmid pM206-OXA181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018836	Escherichia coli strain M513 plasmid pM513-OXA181, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP025007	Klebsiella pneumoniae strain AUSMDU00003562 plasmid pAUSMDU3562-2, complete sequence	23051-23080	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP042935	Escherichia coli 042 plasmid p1-Ec-BERN-042, complete sequence	7420-7449	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021759	Klebsiella pneumoniae strain AR_0138 plasmid tig00000002, complete sequence	39031-39060	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021901	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0136 plasmid tig00001456_pilon, complete sequence	41109-41138	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MG773377	Escherichia coli strain LSB54 plasmid pLSB54-NDM-5, complete sequence	14230-14259	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MG833404	Kluyvera intermedia plasmid pEnin-51781cz, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MG833405	Escherichia coli plasmid pEsco-4382cz, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021738	Escherichia coli strain AR_0150 plasmid tig00000260, complete sequence	14157-14186	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP036205	Escherichia coli strain L725 plasmid pNDM5-L725, complete sequence	6803-6832	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_LR595693	Escherichia coli isolate EcMAD1 plasmid pEcMAD2	19241-19270	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412917	Escherichia coli strain ABC264 plasmid pABC264-OXA-181, complete sequence	23197-23226	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372393	Klebsiella pneumoniae strain ABC369 plasmid pABC369-NDM-5, complete sequence	16973-17002	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK628734	Klebsiella pneumoniae strain GDQ8D112M plasmid pGDQ8D112M-NDM, complete sequence	10115-10144	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK308632	Klebsiella pneumoniae strain LDR plasmid pNDM5-LDR, complete sequence	20598-20627	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372385	Morganella morganii strain ABC140 plasmid pABC140-NDM-1, complete sequence	24309-24338	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372381	Klebsiella pneumoniae strain ABC52 plasmid pABC52-NDM-1, complete sequence	23455-23484	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK773535	Klebsiella pneumoniae strain QDE2 plasmid pQDE2-A, complete sequence	17880-17909	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN276078	Enterobacter cloacae strain GZ6DS3 plasmid pHN6DS3,complete sequence	18645-18674	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN276079	Escherichia coli strain GZ7CS2 plasmid pHN7CS2,complete sequence	18645-18674	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN276082	Citrobacter freundii strain GZ7DS4 plasmid pHN7DS4,complete sequence	18391-18420	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP032424	Escherichia coli strain SCEC020001 plasmid pNDM5_020001, complete sequence	8078-8107	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK033580	Escherichia coli strain HZ11 plasmid pHNHZ11-1, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK033579	Escherichia coli strain YX6P67 plasmid pHNYX667-1, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK033583	Escherichia coli strain HZ18 plasmid pHNHZ18-1, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH909333	Klebsiella pneumoniae strain 7-SP plasmid p7SP-NDM, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH909346	Klebsiella pneumoniae strain 20130907-4 plasmid p309074-NDM, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH909335	Klebsiella pneumoniae strain 11-SP plasmid p11SP-NDM, complete sequence	25754-25783	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK033581	Escherichia coli strain YX6P58 plasmid pHNYX658-1, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK033578	Escherichia coli strain YX6P44 plasmid pHNYX644-1, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH286949	Escherichia coli strain AHM6C87 plasmid pHNAH687, complete sequence	16765-16794	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234505	Escherichia coli strain CRE3694 plasmid pNDM-HK3694, complete sequence	24815-24844	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH917282	Klebsiella pneumoniae strain A457 plasmid pA457-NDA, complete sequence	25750-25779	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH286946	Escherichia coli strain AHM5C66 plasmid pHNAH566, complete sequence	16680-16709	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234499	Escherichia coli strain CRE3836 plasmid pNDM-HK3836, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH917280	Klebsiella pneumoniae strain QDE2 plasmid pQDE2-NDM, complete sequence	9576-9605	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234509	Escherichia coli strain CRE2967 plasmid pNDM-HK2967, complete sequence	19051-19080	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH286947	Escherichia coli strain AHM6C11 plasmid pHNAH611, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH349095	Escherichia coli strain 948 plasmid pMTC948, complete sequence	14482-14511	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372386	Klebsiella pneumoniae strain BC700 plasmid pBC700-NDM-1, complete sequence	23455-23484	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412914	Klebsiella pneumoniae strain ABC220 plasmid pABC220-KPC-2, complete sequence	17234-17263	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412915	Klebsiella pneumoniae strain ABC260 plasmid pABC260-OXA-181, complete sequence	23198-23227	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412920	Klebsiella pneumoniae strain BC-13-947 plasmid pBC947-OXA-181, complete sequence	23197-23226	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234501	Klebsiella pneumoniae strain CRE3816 plasmid pNDM-HK3816, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH286950	Escherichia coli strain AHM6C88 plasmid pHNAH688, complete sequence	16765-16794	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH161191	Klebsiella pneumoniae strain SCKLB138 plasmid pSCKLB138-2, complete sequence	4644-4673	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234504	Klebsiella pneumoniae strain CRE3706 plasmid pNDM-HK3706, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH781720	Klebsiella pneumoniae strain SCKLB684 plasmid pSCKLB684-ndm, complete sequence	5899-5928	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412916	Escherichia coli strain ABC239 plasmid pABC239-OXA-181, complete sequence	23197-23226	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372391	Escherichia coli strain ABC268 plasmid pABC268-NDM-5, complete sequence	16950-16979	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412918	Escherichia coli strain ABC356 plasmid pABC356, complete sequence	23197-23226	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK412919	Escherichia coli strain ABC381 plasmid pABC381-OXA-181, complete sequence	23197-23226	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372388	Enterobacter cloacae strain ABC302 plasmid pABC302-NDM-4, complete sequence	21120-21149	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372380	Enterobacter cloacae strain ABC40 plasmid pABC40-NDM-1, complete sequence	25753-25782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK372382	Escherichia coli strain ABC54 plasmid pABC54-NDM-1, complete sequence	24741-24770	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234503	Escherichia coli strain CRE3712 plasmid pNDM-HK3712, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG252891	Escherichia coli strain Esco-5256cz plasmid pEsco-5256cz, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF547509	Escherichia coli strain P785MEM plasmid pP785-NDM5, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF458176	Escherichia coli strain CCD1 plasmid pNDM-20 clone ST1114, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF547507	Escherichia coli strain P788A-032 plasmid pP788A-NDM5, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF547511	Escherichia coli strain P744 plasmid pP744T-NDM5, complete sequence	17123-17152	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF547508	Escherichia coli strain P855MEM plasmid pP855-NDM5, complete sequence	17738-17767	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG252892	Enterobacter cloacae strain Encl-922cz plasmid pEncl-922cz, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG545911	Escherichia coli strain EC463 plasmid pEC463-NDM5, complete sequence	16315-16344	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG591703	Escherichia coli strain EC36 plasmid pNDM-EC36, complete sequence	15787-15816	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG702491	Escherichia coli strain CC1706-01 plasmid pD6-OXA_1_1, complete sequence	830-859	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH061381	Enterobacter cloacae strain En_MCR4 plasmid pEn_NDM, complete sequence	17457-17486	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH143074	Escherichia coli strain CZEC1507017 plasmid pTBCZNDM03, complete sequence	8720-8749	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH286948	Escherichia coli strain AHM6C71 plasmid pHNAH671, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH286945	Escherichia coli strain AHM5C07 plasmid pHNAH507-1, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH594478	Citrobacter freundii strain AA593 plasmid pIBAC_Incx3_A/C, complete sequence	158080-158109	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH105052	Escherichia coli strain EC600 plasmid pSL131T_IncX3, complete sequence	23509-23538	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH523639	Escherichia coli strain JN05 plasmid pJN05NDM7, complete sequence	17879-17908	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KY499796	Klebsiella pneumoniae strain IN03-01 plasmid pIN03-01, complete sequence	20978-21007	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF415608	Enterobacter cloacae strain hhy03 plasmid pNDM-BJ03, complete sequence	24938-24967	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH234502	Escherichia coli strain CRE3774 plasmid pNDM-HK3774, complete sequence	17124-17153	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG252893	Raoultella ornithinolytica strain pRor-30818cz plasmid Ror-30818cz, complete sequence	4570-4599	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041048	Citrobacter sp. CF971 plasmid pBM527-2, complete sequence	11186-11215	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP025948	Escherichia coli strain SCEC020023 plasmid pNDM21_020023, complete sequence	8551-8580	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX618696	Escherichia coli strain NRS18 plasmid pEC-NRS18, complete sequence	29268-29297	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX618698	Escherichia coli strain 243 plasmid pEC-243, complete sequence	31901-31930	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX618697	Escherichia coli strain 393 plasmid pEC-393, complete sequence	29395-29424	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX618702	Escherichia coli strain 147 plasmid pEC-147, complete sequence	31901-31930	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX618701	Escherichia coli strain 170 plasmid pEC-170, complete sequence	31901-31930	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF150120	Klebsiella pneumoniae strain A64477 plasmid pKP64477d, complete sequence	39271-39300	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MF679147	Escherichia coli plasmid pBJ114T-190, complete sequence	70595-70624	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX756453	Klebsiella pneumoniae strain 1194/11 plasmid pKP1194a, complete sequence	41640-41669	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KX348144	Klebsiella pneumoniae strain Kp01 plasmid pKPC_Kp01, complete sequence	24915-24944	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KT005457	Klebsiella variicola strain KS22 plasmid pKS22, complete sequence	23157-23186	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_KP765744	Enterobacter cloacae strain ECN49 plasmid pNDM-ECN49, complete sequence	38626-38655	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP042339	Escherichia coli strain GZ04-0086 plasmid pNDM5-GZ04_A, complete sequence	35251-35280	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP043050	Klebsiella pneumoniae strain KLP268 plasmid pKLP268-1, complete sequence	22140-22169	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP014006	Klebsiella pneumoniae subsp. pneumoniae strain NUHL24835 plasmid unnamed2, complete sequence	3573-3602	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041033	Escherichia coli strain PT109 plasmid pLB_OXA-181_PT109, complete sequence	16463-16492	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP048332	Escherichia coli strain 10 plasmid p010_B-OXA181, complete sequence	33268-33297	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034957	Escherichia coli strain SCEC020026 plasmid pNDM5_020026, complete sequence	4883-4912	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP049602	Klebsiella aerogenes strain 18-2341 plasmid pSECR18-2341_NDM, complete sequence	3465-3494	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP010395	Klebsiella pneumoniae strain 34618 plasmid p34618-43.380kb, complete sequence	40832-40861	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP020512	Escherichia coli strain 165 plasmid unnamed3, complete sequence	39939-39968	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP053726	Escherichia coli strain CP66-6_Sichuan plasmid pCP66-6-IncX3, complete sequence	43861-43890	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034744	Escherichia coli strain L65 plasmid pL65-9, complete sequence	34642-34671	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP051221	Escherichia coli strain SFE8 plasmid pSCZP2, complete sequence	10481-10510	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP026727	Escherichia coli strain 266917_2 plasmid p266917_2_04, complete sequence	23709-23738	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP014069	Citrobacter amalonaticus strain FDAARGOS_165 plasmid unnamed	44429-44458	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP029245	Escherichia coli strain ECCRA-119 plasmid pTB203, complete sequence	778-807	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP025041	Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_4, complete sequence	1050-1079	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP052768	Salmonella enterica subsp. enterica strain LHST_2018 plasmid pLHST2018_IncX3, complete sequence	33875-33904	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN061454	Enterobacter cloacae strain EC-14-60 plasmid pECL-14-60-NDM-1, complete sequence	4419-4448	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_025130	Raoultella planticola strain RJA274 plasmid NDM-1, complete sequence	36010-36039	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP011982	Klebsiella pneumoniae 500_1420 plasmid p500_1420-51.662kb, complete sequence	1944-1973	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP020839	Klebsiella pneumoniae strain BK13043 plasmid pBK13043-2, complete sequence	10690-10719	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP020839	Klebsiella pneumoniae strain BK13043 plasmid pBK13043-2, complete sequence	54069-54098	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_019157	Klebsiella pneumoniae plasmid pIncX-SHV, complete sequence	34694-34723	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP033057	Morganella morganii strain L241 plasmid pNDM5-L241, complete sequence	42472-42501	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP037965	Klebsiella pneumoniae strain SCKP020135 plasmid pNDM1_020135, complete sequence	20158-20187	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP022694	Klebsiella pneumoniae subsp. pneumoniae strain AUSMDU00008079 plasmid pAUSMDU00008079_03, complete sequence	29267-29296	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP025215	Klebsiella pneumoniae strain HZW25 plasmid unnamed4, complete sequence	32318-32347	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP022351	Klebsiella michiganensis strain K516 plasmid pK516_NDM5, complete sequence	26989-27018	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024820	Citrobacter freundii strain CRCB-101 plasmid pCRCB-101_1, complete sequence	37060-37089	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP046274	Enterobacter hormaechei strain E70 plasmid pE70-NDM1, complete sequence	22816-22845	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP039811	Klebsiella pneumoniae strain C2660 plasmid pC2660-4-NDM, complete sequence	13943-13972	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP029100	Klebsiella pneumoniae strain AR438 plasmid unnamed2	6689-6718	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP036195	Klebsiella pneumoniae strain BA34918 plasmid pIncX3	25318-25347	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024814	Enterobacter sp. CRENT-193 plasmid pCRENT-193_2, complete sequence	6620-6649	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP048327	Escherichia coli strain 61 plasmid p61_A-OXA181, complete sequence	33266-33295	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021542	Klebsiella pneumoniae strain AR_0047 plasmid tig00000003, complete sequence	27679-27708	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024828	Escherichia coli strain CREC-544 plasmid pCREC-544_2, complete sequence	19925-19954	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP024818	Escherichia coli strain CREC-629 plasmid pCREC-629_3, complete sequence	12062-12091	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP036312	Enterobacter hormaechei strain WCHEH090011 plasmid pNDM5_090011, complete sequence	27668-27697	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP003997	Klebsiella pneumoniae subsp. pneumoniae Kp13 plasmid pKP13d, complete sequence	41806-41835	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP048325	Escherichia coli strain 64 plasmid p64_C-OXA181, complete sequence	34598-34627	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP018951	Escherichia coli strain Ecol_276 plasmid pEC276_2, complete sequence	1981-2010	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP048321	Escherichia coli strain 32-4 plasmid p32-4_K-OXA181, complete sequence	34587-34616	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP022575	Klebsiella pneumoniae strain BIC-1 plasmid pBIC-1b, complete sequence	23809-23838	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN792919	Enterobacter hormaechei subsp. steigerwaltii strain ST190 plasmid pLAU_ENM17_OXA181, complete sequence	43363-43392	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP050375	Klebsiella pneumoniae strain 50595 plasmid p50595_OXA_181, complete sequence	50398-50427	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP021715	Klebsiella pneumoniae strain AR_0129 plasmid tig00000002, complete sequence	20409-20438	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP045195	Klebsiella pneumoniae strain YML0508 plasmid pOXA181_YML0508, complete sequence	32379-32408	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP028182	Klebsiella pneumoniae strain CFSAN054110 plasmid pGMI16-005_02, complete sequence	12119-12148	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	LC536680	Klebsiella pneumoniae MyNCGM036 plasmid pMyNCGM036, complete sequence	33268-33297	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_019384	Klebsiella pneumoniae plasmid pKpS90, complete sequence	46431-46460	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP027051	Klebsiella pneumoniae strain 20_GR_12 plasmid IncX3, complete sequence	33937-33966	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP031138	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_4, complete sequence	20372-20401	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP026577	Escherichia coli strain WCHEC005237 plasmid pNDM5_005237, complete sequence	22072-22101	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP028577	Escherichia coli strain WCHEC005784 plasmid pNDM5_005784, complete sequence	8551-8580	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP032190	Klebsiella pneumoniae strain AR_0075 plasmid unnamed5, complete sequence	15600-15629	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP015825	Klebsiella pneumoniae isolate blood sample 2 plasmid 3, complete sequence	17460-17489	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP023188	Klebsiella michiganensis strain K518 plasmid pK518_NDM5, complete sequence	22186-22215	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP027157	Klebsiella pneumoniae strain AR_0361 plasmid unnamed6	24338-24367	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP028786	Klebsiella pneumoniae strain SCKP020049 plasmid pNDM1_020049, complete sequence	4331-4360	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP028536	Enterobacter hormaechei strain SCEH020042 plasmid pNDM5_020042, complete sequence	29736-29765	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP043513	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed2, complete sequence	14920-14949	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP031373	Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvST101_6, complete sequence	20404-20433	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP041938	Klebsiella pneumoniae strain KP14003 plasmid pNDM-KP14003, complete sequence	18295-18324	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP048028	Escherichia coli strain GZEC065 plasmid pNDM5-GZEC065, complete sequence	35199-35228	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP023202	Escherichia coli strain TUM18780 plasmid pMTY18780-5_IncX3, complete sequence	33266-33295	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP023210	Escherichia coli strain TUM18781 plasmid pMTY18781-5, complete sequence	3228-3257	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP034591	Escherichia coli strain L37 plasmid pL37-3, complete sequence	45-74	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	CP028781	Klebsiella pneumoniae subsp. pneumoniae strain SCKP020046 plasmid pNDM5_020046, complete sequence	112955-112984	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP026015	Klebsiella variicola strain 13450 plasmid p13450-3, complete sequence	39834-39863	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018142	Escherichia coli strain M213 isolate M213 plasmid pM213_X3, complete sequence	28395-28424	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018146	Escherichia coli strain M216 isolate M216 plasmid pM216_X3, complete sequence	28395-28424	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_AP018141	Escherichia coli strain M110 isolate M110 plasmid pM110_X3, complete sequence	28395-28424	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP026476	Escherichia coli strain KBN10P04869 plasmid pKBN10P04869C, complete sequence	27767-27796	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	MN937240	Enterobacter cloacae strain BSI034 plasmid pBSI034-NDM1, complete sequence	19860-19889	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP027700	Klebsiella pneumoniae strain KP30835 plasmid unnamed5, complete sequence	6658-6687	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK450346	Escherichia coli strain Z244 plasmid pNDM-Z244, complete sequence	29013-29042	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK450347	Escherichia coli strain Z214 plasmid pNDM-Z214, complete sequence	27237-27266	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK450348	Klebsiella pneumoniae strain K725 plasmid pNDM-K725, complete sequence	1541-1570	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MN064714	Klebsiella pneumoniae strain RJY9645 plasmid pY9645-NDM5, complete sequence	23705-23734	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH917283	Klebsiella pneumoniae strain A575 plasmid pA575-NDM, complete sequence	36011-36040	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH105050	Salmonella enterica subsp. enterica serovar Lomita strain SL131 plasmid pSL131_IncA/C-IncX3, complete sequence	202447-202476	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH909343	Klebsiella pneumoniae strain 1012018 plasmid p12018-NDM, complete sequence	35167-35196	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH909347	Klebsiella pneumoniae strain 362713 plasmid p362713-NDM, complete sequence	33029-33058	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH347484	Escherichia coli strain 135 plasmid pEC135, complete sequence	35431-35460	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK317995	Klebsiella pneumoniae strain CRE plasmid pAN65-3, complete sequence	15735-15764	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK264770	Klebsiella pneumoniae strain KP89 plasmid pKP89, complete sequence	41807-41836	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH107030	Klebsiella pneumoniae strain CZPF140026 plasmid pTBCZNDM01, complete sequence	33852-33881	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH341575	Klebsiella pneumoniae strain MYKLB95 plasmid pMYKLB95-2, complete sequence	44890-44919	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK256964	Escherichia coli strain R15 plasmid pR15_NDM-5, complete sequence	18404-18433	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK416154	Escherichia coli strain AR24.2b plasmid pAN-OXA-181, complete sequence	44031-44060	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MK450349	Klebsiella aerogenes strain CR33 plasmid pNDM-CR33, complete sequence	29012-29041	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP020090	Enterobacter cloacae strain PIMB10EC27 plasmid pEC27-1, complete sequence	25815-25844	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG825382	Escherichia coli strain 977 plasmid p977-NDM, complete sequence	35261-35290	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG825368	Escherichia coli strain 787 plasmid p787-NDM, complete sequence	35261-35290	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MG825384	Escherichia coli strain 1079 plasmid p1079-NDM, complete sequence	35261-35290	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MF344560	Enterobacter hormaechei strain 128379 plasmid p128379-NDM, complete sequence	38753-38782	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH328008	Enterobacter cloacae strain 150 plasmid pEC150, complete sequence	23836-23865	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_MH094148	Escherichia coli strain A0917122A14A plasmid pNDM-5_A0917122, complete sequence	29224-29253	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP031725	Enterobacter hormaechei strain WCHEH020038 plasmid pNDM5_020038, complete sequence	10480-10509	7	0.767
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NZ_CP027204	Escherichia coli strain WCHEC025943 plasmid pNDM5_025943, complete sequence	22575-22604	7	0.767
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_010180	Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence	125148-125180	7	0.788
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_018689	Bacillus thuringiensis MC28 plasmid pMC429, complete sequence	316165-316197	7	0.788
CP035945_2	2.10\|1095881\|34\|CP035945\|CRISPRCasFinder,CRT,PILER-CR	1095881-1095914	34	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	196542-196575	8	0.765
CP035945_2	2.10\|1095881\|34\|CP035945\|CRISPRCasFinder,CRT,PILER-CR	1095881-1095914	34	MH617217	Microviridae sp. isolate ctda15, complete genome	1732-1765	8	0.765
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	JQ680370	Unidentified phage clone 2204_scaffold812 genomic sequence	42760-42789	8	0.733
CP035945_8	8.2\|2947957\|30\|CP035945\|CRISPRCasFinder	2947957-2947986	30	NC_047911	Faecalibacterium phage FP_Lagaffe, complete genome	6035-6064	8	0.733
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP034684	Bacillus sp. BD59S plasmid pBTBD59S1, complete sequence	39469-39501	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP009332	Bacillus thuringiensis strain HD1011 plasmid 3, complete sequence	12430-12462	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	95775-95807	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	769-801	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	71398-71430	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP053977	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed1, complete sequence	17990-18022	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	127807-127839	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP031073	Bacillus mycoides strain BPN401 plasmid pl50, complete sequence	7751-7783	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_011777	Bacillus cereus AH820 plasmid pAH820_272, complete sequence	85422-85454	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	117122-117154	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	284492-284524	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	126676-126708	8	0.758
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	93471-93503	8	0.758
CP035945_2	2.1\|1095290\|34\|CP035945\|CRISPRCasFinder,CRT	1095290-1095323	34	MG710528	Escherichia phage GER2, complete genome	26194-26227	9	0.735
CP035945_2	2.7\|1095683\|34\|CP035945\|CRISPRCasFinder,CRT,PILER-CR	1095683-1095716	34	AP018478	Mycobacterium phage A6 DNA, complete sequence	1628-1661	9	0.735
CP035945_2	2.7\|1095683\|34\|CP035945\|CRISPRCasFinder,CRT,PILER-CR	1095683-1095716	34	AP018477	Mycobacterium phage BK1 DNA, complete sequence	1628-1661	9	0.735
CP035945_8	8.3\|2948020\|30\|CP035945\|CRISPRCasFinder	2948020-2948049	30	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1744629-1744658	9	0.7
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	CP037991	Bacillus mycoides strain TH26 plasmid unnamed1, complete sequence	53103-53135	9	0.727
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	MG584725	Bacillus phage BVE2, complete genome	250-282	9	0.727
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP031644	Bacillus anthracis strain MCCC 1A01412 plasmid p1, complete sequence	64050-64082	9	0.727
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_010180	Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence	68483-68515	9	0.727
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	47341-47373	9	0.727
CP035945_10	10.4\|3862686\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862686-3862718	33	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	149966-149998	9	0.727
CP035945_9	9.8\|3566609\|35\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3566609-3566643	35	LC494302	Escherichia phage SP27 DNA, complete genome	178449-178483	10	0.714
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NC_011775	Bacillus cereus G9842 plasmid pG9842_209, complete sequence	143941-143973	10	0.697
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	CP013001	Bacillus thuringiensis strain XL6 plasmid, complete sequence	261611-261643	10	0.697
CP035945_10	10.2\|3862552\|33\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	3862552-3862584	33	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	223895-223927	10	0.697
CP035945_12	12.22\|5393627\|34\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	5393627-5393660	34	MF459647	Erwinia phage vB_EamM_Joad, complete genome	115116-115149	10	0.706
CP035945_12	12.22\|5393627\|34\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	5393627-5393660	34	MF459646	Erwinia phage vB_EamM_RisingSun, complete genome	115193-115226	10	0.706
CP035945_12	12.10\|5392826\|34\|CP035945\|PILER-CR,CRISPRCasFinder,CRT	5392826-5392859	34	MH632120	Mycobacterium phage Thonko, complete genome	54914-54947	12	0.647

1. spacer 2.3|1095422|33|CP035945|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042975 (Klebsiella pneumoniae strain KPN55602 plasmid pK55602_1, complete sequence) position: , mismatch: 6, identity: 0.818

cggaatccg----tgtggatggtgatatcgaaaaagt	CRISPR spacer
----atccggagctgtggatgcttatatcgaaaaagt	Protospacer
    *****    ******** * *************

2. spacer 8.1|2947894|30|CP035945|CRISPRCasFinder matches to MG592548 (Vibrio phage 1.182.O._10N.286.46.E1, partial genome) position: , mismatch: 7, identity: 0.767

cggtgcagaaaaatgccggaaacacatcaa	CRISPR spacer
tgacccagaaaactgccggaaagacatcat	Protospacer
.*.. ******* ********* ******

3. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MK088486 (Klebsiella pneumoniae plasmid pHNHZ604-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

4. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP052170 (Klebsiella pneumoniae strain F16KP0075 plasmid pF16KP0075-3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

5. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX470734 (Escherichia coli strain Ecoli14-55 plasmid pEC55-NDM4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

6. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX674681 (Escherichia coli strain AS-01 plasmid pNDM5_AS, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

7. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX470735 (Escherichia coli strain Ecoli15-50 plasmid pEC50-NDM7, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

8. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX683284 (Escherichia coli strain EcU443 plasmid pECSEV_02, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

9. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX833071 (Escherichia coli strain AD-19R plasmid pAD-19R clone ST48, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

10. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY296103 (Enterobacter cloacae strain 13E169 plasmid pHN84NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

11. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY499797 (Klebsiella pneumoniae strain TH02-34 plasmid pTH02-34, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

12. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY659388 (Citrobacter freundii strain 145 plasmid pCr-145, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

13. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY659387 (Citrobacter freundii strain 30 plasmid pCfr-30, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

14. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY978629 (Cronobacter sakazakii strain 505108 plasmid p505108-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

15. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF072961 (Citrobacter freundii strain P10159 plasmid pP10159-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

16. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY435936 (Escherichia coli strain WCHEC005215 plasmid pNDM5_WCHEC0215, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

17. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MG228426 (Escherichia coli strain BO15V plasmid pKP_BO_OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

18. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KU934011 (Serratia marcescens strain 427862 plasmid IncX-3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

19. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX523903 (Klebsiella pneumoniae strain Kpn-29144/15 plasmid pOXA-181_29144, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

20. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KU647721 (Escherichia coli strain CQ02-121 plasmid pCQ02-121, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

21. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX960110 (Escherichia coli strain CREC-TJ2 plasmid pCREC-TJ2-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

22. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KU167609 (Escherichia coli strain QD29 plasmid pNDM-QD29, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

23. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX960109 (Escherichia coli strain CREC-A6 plasmid pCREC-A6-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

24. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY041843 (Escherichia coli strain ZHDC40 plasmid pZHDC40, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

25. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KU963389 (Escherichia coli strain ECO37 plasmid ECO37P1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
attgacgagagagcgccggaacaatgccgg	Protospacer
*.  *. ******.*********.******

26. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KU314941 (Klebsiella pneumoniae isolate KP04 plasmid pKP04NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

27. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX094555 (Escherichia coli strain ZHDC33 plasmid pZHDC33, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

28. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX214669 (Escherichia coli strain KW53T plasmid pKW53T-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

29. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KM400601 (Klebsiella pneumoniae strain Kp0003 plasmid pJEG027, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

30. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KT362706 (Klebsiella pneumoniae strain ST512 plasmid p45-IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

31. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KP987216 (Citrobacter freundii strain 112298 plasmid p112298-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

32. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KT824791 (Escherichia coli strain 1929 plasmid pEc1929, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

33. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KP776609 (Escherichia coli strain OM26 plasmid pOM26-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

34. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KU167608 (Escherichia coli strain QD28 plasmid pNDM-QD28, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

35. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP043333 (Proteus mirabilis strain CRPM10 plasmid pNDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

36. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP018435 (Klebsiella pneumoniae strain MNCRE53 plasmid pMNCRE53_2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

37. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP023194 (Escherichia coli strain TUM18530 plasmid pMTY18530-4_lncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

38. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP040399 (Escherichia coli strain BA22372 plasmid pOXA181_22372, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

39. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034284 (Klebsiella pneumoniae strain I72 plasmid p72_OXA181_X3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

40. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MK088485 (Escherichia coli plasmid pHN4109c, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

41. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP049352 (Escherichia coli strain 3R plasmid p3R-4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

42. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP012995 (Klebsiella pneumoniae strain KpN06 plasmid pKpN06-NDM7, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

43. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041931 (Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374D, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

44. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP029735 (Citrobacter sp. CRE-46 strain AR_0157 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

45. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034965 (Escherichia coli strain WCHEC020032 plasmid pNDM5_020032, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

46. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to KX023261 (Escherichia coli plasmid pSCE516-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

47. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP011987 (Klebsiella pneumoniae UHKPC07 plasmid pUHKPC07-74.026kb, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

48. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN175389 (Klebsiella pneumoniae strain KP-13-8 plasmid pKP-13-8-NDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

49. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN092230 (Escherichia coli plasmid pJN11NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

50. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN017707 (Escherichia coli plasmid pCNUH-11, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

51. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041956 (Escherichia coli strain EC2 plasmid pEC2_1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

52. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041947 (Klebsiella pneumoniae strain KP2 plasmid pKP2_1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

53. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP011992 (Klebsiella pneumoniae UHKPC33 plasmid pUHKPC33-43.380kb, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

54. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN200942 (Escherichia coli strain E648 plasmid pE648NDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

55. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_019162 (Klebsiella pneumoniae strain CRE380 plasmid pNDM-HN380, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

56. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP018423 (Klebsiella pneumoniae strain MNCRE69 plasmid pMNCRE69_2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

57. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP012990 (Klebsiella pneumoniae strain KpN01 plasmid pKpN01-NDM7, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

58. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021836 (Klebsiella pneumoniae strain AR_0120 plasmid tig00000583_pilon, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

59. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP010881 (Escherichia coli strain MNCRE44 plasmid pMNCRE44_5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

60. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034323 (Klebsiella pneumoniae isolate KSH203 plasmid pKSH203-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

61. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021692 (Escherichia coli strain AR_0151 plasmid tig00001251, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

62. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024833 (Escherichia coli strain CREC-532 plasmid pCREC-532_3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

63. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021534 (Escherichia coli strain AR_0149 plasmid tig00000221, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

64. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021682 (Escherichia coli strain AR_0162 plasmid tig00003144, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

65. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP019679 (Escherichia coli strain GSH8M-2 plasmid pGSH8M-2-4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

66. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to KY930325 (Klebsiella pneumoniae plasmid pUCLAKPC2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

67. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_020811 (Klebsiella pneumoniae strain KPN5047 plasmid pKPN5047, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

68. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to KR822247 (Escherichia coli strain E0083033-2 plasmid pEc2A, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

69. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024825 (Escherichia coli strain CREC-591 plasmid pCREC-591_4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

70. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP036179 (Escherichia coli strain WCHEC025970 plasmid pNDM5_025970, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

71. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MG570092 (Escherichia coli plasmid pSTIB_IncX3_OXA_181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

72. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_023914 (Enterobacter cloacae strain CRE727 plasmid pNDM-HF727, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

73. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP009776 (Klebsiella pneumoniae subsp. pneumoniae strain KPNIH32 plasmid pKPC-def, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

74. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP008799 (Klebsiella pneumoniae subsp. pneumoniae KPNIH24 plasmid pKPN-819, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

75. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP048346 (Escherichia coli strain 124 plasmid p124_B-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

76. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP028705 (Escherichia coli strain VH1 plasmid pVH1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

77. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041053 (Enterobacter hormaechei strain C126 plasmid pEnC126OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

78. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP020074 (Klebsiella pneumoniae strain AR_0115 plasmid tig00000004, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

79. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP020111 (Klebsiella pneumoniae strain AR_0098 plasmid tig00000003, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

80. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN178638 (Kluyvera cryocrescens strain SCW13 plasmid pNDM1_SCW13, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

81. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP038280 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

82. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP012563 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

83. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP050158 (Enterobacter cloacae plasmid Carbapenemase(NDM-1)_IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

84. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP035910 (Klebsiella pneumoniae strain BA4656 plasmid pIncX3) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

85. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP023897 (Escherichia coli strain FDAARGOS_433 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

86. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034133 (Klebsiella quasipneumoniae strain G4584 plasmid pG4584_52.4Kb, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

87. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP050157 (Escherichia coli plasmid Carbapenemase(NDM-5)_IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

88. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP050161 (Escherichia coli plasmid Carbapenemase(NDM-1)_IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

89. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to KX507346 (Escherichia coli plasmid pECNDM101, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

90. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_LR130550 (Klebsiella pneumoniae strain KPC2 isolate KPC2 plasmid 3) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

91. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024806 (Escherichia coli strain AMA1167 plasmid pAMA1167-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

92. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN335922 (Escherichia coli strain GD1-16 plasmid pNDM-T16, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

93. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP029386 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074 plasmid pNDM6_040074, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

94. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to LC545851 (Escherichia coli Ec-MW07 plasmid pEc-MW07_NDM DNA, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

95. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MT028409 (Klebsiella pneumoniae strain BS407 plasmid pBS407-3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

96. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN865121 (Escherichia coli strain SCNJ06 plasmid pNDM5_SCNJ06, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

97. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP052507 (Klebsiella pneumoniae strain B16KP0226 plasmid pB16KP0226-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

98. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_020552 (Citrobacter freundii plasmid pYE315203, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

99. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to AP023227 (Escherichia coli YJ3 plasmid pYJ3-NDM1 DNA, complete genome) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

100. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN227183 (Klebsiella pneumoniae strain 709 plasmid pKP709-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

101. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_022740 (Klebsiella pneumoniae strain MGR-K194 plasmid pNDM_MGR194, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

102. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP019073 (Escherichia coli strain CRE1493 plasmid p1493-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

103. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP031884 (Klebsiella pneumoniae strain WCHKP095845 plasmid pNDM1_095845, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

104. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP035125 (Escherichia coli strain EC25 plasmid pEC25_NDM-7, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

105. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MK715437 (Klebsiella pneumoniae subsp. pneumoniae strain SCNJ1 plasmid pNDM5-SCNJ1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

106. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP054267 (Klebsiella pneumoniae strain 39427 plasmid pKPN39427.3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

107. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP028718 (Klebsiella pneumoniae strain SCM96 plasmid pSCM96-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

108. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP032889 (Escherichia coli strain SCEC020022 plasmid pNDM5_020022, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

109. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018837 (Escherichia coli strain M517 plasmid pM517-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

110. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018838 (Escherichia coli strain M518 plasmid pM518-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

111. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018831 (Enterobacter hormaechei subsp. xiangfangensis strain M206 plasmid pM206-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

112. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018836 (Escherichia coli strain M513 plasmid pM513-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

113. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP025007 (Klebsiella pneumoniae strain AUSMDU00003562 plasmid pAUSMDU3562-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

114. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP042935 (Escherichia coli 042 plasmid p1-Ec-BERN-042, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

115. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021759 (Klebsiella pneumoniae strain AR_0138 plasmid tig00000002, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

116. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021901 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0136 plasmid tig00001456_pilon, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

117. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MG773377 (Escherichia coli strain LSB54 plasmid pLSB54-NDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

118. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MG833404 (Kluyvera intermedia plasmid pEnin-51781cz, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

119. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MG833405 (Escherichia coli plasmid pEsco-4382cz, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

120. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021738 (Escherichia coli strain AR_0150 plasmid tig00000260, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

121. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP036205 (Escherichia coli strain L725 plasmid pNDM5-L725, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

122. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_LR595693 (Escherichia coli isolate EcMAD1 plasmid pEcMAD2) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

123. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412917 (Escherichia coli strain ABC264 plasmid pABC264-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

124. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372393 (Klebsiella pneumoniae strain ABC369 plasmid pABC369-NDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

125. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK628734 (Klebsiella pneumoniae strain GDQ8D112M plasmid pGDQ8D112M-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

126. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK308632 (Klebsiella pneumoniae strain LDR plasmid pNDM5-LDR, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

127. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372385 (Morganella morganii strain ABC140 plasmid pABC140-NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

128. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372381 (Klebsiella pneumoniae strain ABC52 plasmid pABC52-NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

129. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK773535 (Klebsiella pneumoniae strain QDE2 plasmid pQDE2-A, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

130. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN276078 (Enterobacter cloacae strain GZ6DS3 plasmid pHN6DS3,complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

131. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN276079 (Escherichia coli strain GZ7CS2 plasmid pHN7CS2,complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

132. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN276082 (Citrobacter freundii strain GZ7DS4 plasmid pHN7DS4,complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

133. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP032424 (Escherichia coli strain SCEC020001 plasmid pNDM5_020001, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

134. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK033580 (Escherichia coli strain HZ11 plasmid pHNHZ11-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

135. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK033579 (Escherichia coli strain YX6P67 plasmid pHNYX667-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

136. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK033583 (Escherichia coli strain HZ18 plasmid pHNHZ18-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

137. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH909333 (Klebsiella pneumoniae strain 7-SP plasmid p7SP-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

138. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH909346 (Klebsiella pneumoniae strain 20130907-4 plasmid p309074-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

139. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH909335 (Klebsiella pneumoniae strain 11-SP plasmid p11SP-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

140. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK033581 (Escherichia coli strain YX6P58 plasmid pHNYX658-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

141. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK033578 (Escherichia coli strain YX6P44 plasmid pHNYX644-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

142. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH286949 (Escherichia coli strain AHM6C87 plasmid pHNAH687, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

143. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234505 (Escherichia coli strain CRE3694 plasmid pNDM-HK3694, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

144. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH917282 (Klebsiella pneumoniae strain A457 plasmid pA457-NDA, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

145. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH286946 (Escherichia coli strain AHM5C66 plasmid pHNAH566, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

146. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234499 (Escherichia coli strain CRE3836 plasmid pNDM-HK3836, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

147. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH917280 (Klebsiella pneumoniae strain QDE2 plasmid pQDE2-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

148. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234509 (Escherichia coli strain CRE2967 plasmid pNDM-HK2967, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

149. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH286947 (Escherichia coli strain AHM6C11 plasmid pHNAH611, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

150. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH349095 (Escherichia coli strain 948 plasmid pMTC948, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

151. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372386 (Klebsiella pneumoniae strain BC700 plasmid pBC700-NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

152. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412914 (Klebsiella pneumoniae strain ABC220 plasmid pABC220-KPC-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

153. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412915 (Klebsiella pneumoniae strain ABC260 plasmid pABC260-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

154. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412920 (Klebsiella pneumoniae strain BC-13-947 plasmid pBC947-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

155. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234501 (Klebsiella pneumoniae strain CRE3816 plasmid pNDM-HK3816, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

156. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH286950 (Escherichia coli strain AHM6C88 plasmid pHNAH688, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

157. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH161191 (Klebsiella pneumoniae strain SCKLB138 plasmid pSCKLB138-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

158. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234504 (Klebsiella pneumoniae strain CRE3706 plasmid pNDM-HK3706, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

159. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH781720 (Klebsiella pneumoniae strain SCKLB684 plasmid pSCKLB684-ndm, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

160. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412916 (Escherichia coli strain ABC239 plasmid pABC239-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

161. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372391 (Escherichia coli strain ABC268 plasmid pABC268-NDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

162. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412918 (Escherichia coli strain ABC356 plasmid pABC356, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

163. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK412919 (Escherichia coli strain ABC381 plasmid pABC381-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

164. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372388 (Enterobacter cloacae strain ABC302 plasmid pABC302-NDM-4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

165. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372380 (Enterobacter cloacae strain ABC40 plasmid pABC40-NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

166. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK372382 (Escherichia coli strain ABC54 plasmid pABC54-NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

167. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234503 (Escherichia coli strain CRE3712 plasmid pNDM-HK3712, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

168. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG252891 (Escherichia coli strain Esco-5256cz plasmid pEsco-5256cz, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

169. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF547509 (Escherichia coli strain P785MEM plasmid pP785-NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

170. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF458176 (Escherichia coli strain CCD1 plasmid pNDM-20 clone ST1114, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

171. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF547507 (Escherichia coli strain P788A-032 plasmid pP788A-NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

172. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF547511 (Escherichia coli strain P744 plasmid pP744T-NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

173. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF547508 (Escherichia coli strain P855MEM plasmid pP855-NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

174. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG252892 (Enterobacter cloacae strain Encl-922cz plasmid pEncl-922cz, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

175. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG545911 (Escherichia coli strain EC463 plasmid pEC463-NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

176. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG591703 (Escherichia coli strain EC36 plasmid pNDM-EC36, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

177. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG702491 (Escherichia coli strain CC1706-01 plasmid pD6-OXA_1_1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

178. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH061381 (Enterobacter cloacae strain En_MCR4 plasmid pEn_NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

179. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH143074 (Escherichia coli strain CZEC1507017 plasmid pTBCZNDM03, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

180. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH286948 (Escherichia coli strain AHM6C71 plasmid pHNAH671, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

181. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH286945 (Escherichia coli strain AHM5C07 plasmid pHNAH507-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

182. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH594478 (Citrobacter freundii strain AA593 plasmid pIBAC_Incx3_A/C, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

183. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH105052 (Escherichia coli strain EC600 plasmid pSL131T_IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

184. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH523639 (Escherichia coli strain JN05 plasmid pJN05NDM7, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

185. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KY499796 (Klebsiella pneumoniae strain IN03-01 plasmid pIN03-01, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

186. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF415608 (Enterobacter cloacae strain hhy03 plasmid pNDM-BJ03, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

187. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH234502 (Escherichia coli strain CRE3774 plasmid pNDM-HK3774, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

188. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG252893 (Raoultella ornithinolytica strain pRor-30818cz plasmid Ror-30818cz, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

189. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041048 (Citrobacter sp. CF971 plasmid pBM527-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

190. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP025948 (Escherichia coli strain SCEC020023 plasmid pNDM21_020023, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

191. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX618696 (Escherichia coli strain NRS18 plasmid pEC-NRS18, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

192. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX618698 (Escherichia coli strain 243 plasmid pEC-243, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

193. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX618697 (Escherichia coli strain 393 plasmid pEC-393, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

194. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX618702 (Escherichia coli strain 147 plasmid pEC-147, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

195. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX618701 (Escherichia coli strain 170 plasmid pEC-170, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

196. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF150120 (Klebsiella pneumoniae strain A64477 plasmid pKP64477d, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
attgacgagagagcgccggaacaatgccgg	Protospacer
*.  *. ******.*********.******

197. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MF679147 (Escherichia coli plasmid pBJ114T-190, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

198. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX756453 (Klebsiella pneumoniae strain 1194/11 plasmid pKP1194a, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
attgacgagagagcgccggaacaatgccgg	Protospacer
*.  *. ******.*********.******

199. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KX348144 (Klebsiella pneumoniae strain Kp01 plasmid pKPC_Kp01, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

200. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KT005457 (Klebsiella variicola strain KS22 plasmid pKS22, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

201. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_KP765744 (Enterobacter cloacae strain ECN49 plasmid pNDM-ECN49, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

202. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP042339 (Escherichia coli strain GZ04-0086 plasmid pNDM5-GZ04_A, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

203. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP043050 (Klebsiella pneumoniae strain KLP268 plasmid pKLP268-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

204. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP014006 (Klebsiella pneumoniae subsp. pneumoniae strain NUHL24835 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

205. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041033 (Escherichia coli strain PT109 plasmid pLB_OXA-181_PT109, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

206. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP048332 (Escherichia coli strain 10 plasmid p010_B-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

207. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034957 (Escherichia coli strain SCEC020026 plasmid pNDM5_020026, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

208. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP049602 (Klebsiella aerogenes strain 18-2341 plasmid pSECR18-2341_NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

209. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP010395 (Klebsiella pneumoniae strain 34618 plasmid p34618-43.380kb, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

210. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP020512 (Escherichia coli strain 165 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

211. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP053726 (Escherichia coli strain CP66-6_Sichuan plasmid pCP66-6-IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

212. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034744 (Escherichia coli strain L65 plasmid pL65-9, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

213. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP051221 (Escherichia coli strain SFE8 plasmid pSCZP2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

214. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP026727 (Escherichia coli strain 266917_2 plasmid p266917_2_04, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

215. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP014069 (Citrobacter amalonaticus strain FDAARGOS_165 plasmid unnamed) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

216. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP029245 (Escherichia coli strain ECCRA-119 plasmid pTB203, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

217. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP025041 (Klebsiella pneumoniae strain NU-CRE047 plasmid pNU-CRE047_4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

218. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP052768 (Salmonella enterica subsp. enterica strain LHST_2018 plasmid pLHST2018_IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

219. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN061454 (Enterobacter cloacae strain EC-14-60 plasmid pECL-14-60-NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

220. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_025130 (Raoultella planticola strain RJA274 plasmid NDM-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

221. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP011982 (Klebsiella pneumoniae 500_1420 plasmid p500_1420-51.662kb, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

222. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP020839 (Klebsiella pneumoniae strain BK13043 plasmid pBK13043-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

223. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP020839 (Klebsiella pneumoniae strain BK13043 plasmid pBK13043-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

224. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_019157 (Klebsiella pneumoniae plasmid pIncX-SHV, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

225. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP033057 (Morganella morganii strain L241 plasmid pNDM5-L241, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

226. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP037965 (Klebsiella pneumoniae strain SCKP020135 plasmid pNDM1_020135, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

227. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP022694 (Klebsiella pneumoniae subsp. pneumoniae strain AUSMDU00008079 plasmid pAUSMDU00008079_03, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

228. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP025215 (Klebsiella pneumoniae strain HZW25 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

229. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP022351 (Klebsiella michiganensis strain K516 plasmid pK516_NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

230. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024820 (Citrobacter freundii strain CRCB-101 plasmid pCRCB-101_1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

231. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP046274 (Enterobacter hormaechei strain E70 plasmid pE70-NDM1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

232. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP039811 (Klebsiella pneumoniae strain C2660 plasmid pC2660-4-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

233. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP029100 (Klebsiella pneumoniae strain AR438 plasmid unnamed2) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

234. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP036195 (Klebsiella pneumoniae strain BA34918 plasmid pIncX3) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

235. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024814 (Enterobacter sp. CRENT-193 plasmid pCRENT-193_2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

236. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP048327 (Escherichia coli strain 61 plasmid p61_A-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

237. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021542 (Klebsiella pneumoniae strain AR_0047 plasmid tig00000003, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

238. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024828 (Escherichia coli strain CREC-544 plasmid pCREC-544_2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

239. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP024818 (Escherichia coli strain CREC-629 plasmid pCREC-629_3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

240. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP036312 (Enterobacter hormaechei strain WCHEH090011 plasmid pNDM5_090011, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

241. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP003997 (Klebsiella pneumoniae subsp. pneumoniae Kp13 plasmid pKP13d, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
attgacgagagagcgccggaacaatgccgg	Protospacer
*.  *. ******.*********.******

242. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP048325 (Escherichia coli strain 64 plasmid p64_C-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

243. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP018951 (Escherichia coli strain Ecol_276 plasmid pEC276_2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

244. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP048321 (Escherichia coli strain 32-4 plasmid p32-4_K-OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

245. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP022575 (Klebsiella pneumoniae strain BIC-1 plasmid pBIC-1b, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

246. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN792919 (Enterobacter hormaechei subsp. steigerwaltii strain ST190 plasmid pLAU_ENM17_OXA181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

247. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP050375 (Klebsiella pneumoniae strain 50595 plasmid p50595_OXA_181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

248. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP021715 (Klebsiella pneumoniae strain AR_0129 plasmid tig00000002, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

249. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP045195 (Klebsiella pneumoniae strain YML0508 plasmid pOXA181_YML0508, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

250. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP028182 (Klebsiella pneumoniae strain CFSAN054110 plasmid pGMI16-005_02, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

251. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to LC536680 (Klebsiella pneumoniae MyNCGM036 plasmid pMyNCGM036, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

252. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_019384 (Klebsiella pneumoniae plasmid pKpS90, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

253. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP027051 (Klebsiella pneumoniae strain 20_GR_12 plasmid IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

254. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP031138 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_4, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

255. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP026577 (Escherichia coli strain WCHEC005237 plasmid pNDM5_005237, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

256. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP028577 (Escherichia coli strain WCHEC005784 plasmid pNDM5_005784, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

257. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP032190 (Klebsiella pneumoniae strain AR_0075 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

258. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP015825 (Klebsiella pneumoniae isolate blood sample 2 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

259. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP023188 (Klebsiella michiganensis strain K518 plasmid pK518_NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

260. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP027157 (Klebsiella pneumoniae strain AR_0361 plasmid unnamed6) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

261. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP028786 (Klebsiella pneumoniae strain SCKP020049 plasmid pNDM1_020049, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

262. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP028536 (Enterobacter hormaechei strain SCEH020042 plasmid pNDM5_020042, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

263. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP043513 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

264. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP031373 (Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvST101_6, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

265. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP041938 (Klebsiella pneumoniae strain KP14003 plasmid pNDM-KP14003, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

266. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP048028 (Escherichia coli strain GZEC065 plasmid pNDM5-GZEC065, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

267. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP023202 (Escherichia coli strain TUM18780 plasmid pMTY18780-5_IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

268. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP023210 (Escherichia coli strain TUM18781 plasmid pMTY18781-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

269. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP034591 (Escherichia coli strain L37 plasmid pL37-3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

270. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to CP028781 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP020046 plasmid pNDM5_020046, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

271. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP026015 (Klebsiella variicola strain 13450 plasmid p13450-3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

272. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018142 (Escherichia coli strain M213 isolate M213 plasmid pM213_X3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

273. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018146 (Escherichia coli strain M216 isolate M216 plasmid pM216_X3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

274. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_AP018141 (Escherichia coli strain M110 isolate M110 plasmid pM110_X3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

275. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP026476 (Escherichia coli strain KBN10P04869 plasmid pKBN10P04869C, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

276. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to MN937240 (Enterobacter cloacae strain BSI034 plasmid pBSI034-NDM1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

277. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP027700 (Klebsiella pneumoniae strain KP30835 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
attgacgagagagcgccggaacaatgccgg	Protospacer
*.  *. ******.*********.******

278. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK450346 (Escherichia coli strain Z244 plasmid pNDM-Z244, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

279. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK450347 (Escherichia coli strain Z214 plasmid pNDM-Z214, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

280. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK450348 (Klebsiella pneumoniae strain K725 plasmid pNDM-K725, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

281. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MN064714 (Klebsiella pneumoniae strain RJY9645 plasmid pY9645-NDM5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

282. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH917283 (Klebsiella pneumoniae strain A575 plasmid pA575-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

283. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH105050 (Salmonella enterica subsp. enterica serovar Lomita strain SL131 plasmid pSL131_IncA/C-IncX3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

284. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH909343 (Klebsiella pneumoniae strain 1012018 plasmid p12018-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

285. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH909347 (Klebsiella pneumoniae strain 362713 plasmid p362713-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

286. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH347484 (Escherichia coli strain 135 plasmid pEC135, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

287. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK317995 (Klebsiella pneumoniae strain CRE plasmid pAN65-3, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

288. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK264770 (Klebsiella pneumoniae strain KP89 plasmid pKP89, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
attgacgagagagcgccggaacaatgccgg	Protospacer
*.  *. ******.*********.******

289. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH107030 (Klebsiella pneumoniae strain CZPF140026 plasmid pTBCZNDM01, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

290. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH341575 (Klebsiella pneumoniae strain MYKLB95 plasmid pMYKLB95-2, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

291. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK256964 (Escherichia coli strain R15 plasmid pR15_NDM-5, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

292. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK416154 (Escherichia coli strain AR24.2b plasmid pAN-OXA-181, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

293. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MK450349 (Klebsiella aerogenes strain CR33 plasmid pNDM-CR33, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

294. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP020090 (Enterobacter cloacae strain PIMB10EC27 plasmid pEC27-1, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

295. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG825382 (Escherichia coli strain 977 plasmid p977-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

296. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG825368 (Escherichia coli strain 787 plasmid p787-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

297. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MG825384 (Escherichia coli strain 1079 plasmid p1079-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

298. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MF344560 (Enterobacter hormaechei strain 128379 plasmid p128379-NDM, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

299. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH328008 (Enterobacter cloacae strain 150 plasmid pEC150, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

300. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_MH094148 (Escherichia coli strain A0917122A14A plasmid pNDM-5_A0917122, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

301. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP031725 (Enterobacter hormaechei strain WCHEH020038 plasmid pNDM5_020038, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

302. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NZ_CP027204 (Escherichia coli strain WCHEC025943 plasmid pNDM5_025943, complete sequence) position: , mismatch: 7, identity: 0.767

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
atttacgagagagcgccggaacaatgccgg	Protospacer
*. .*. ******.*********.******

303. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_010180 (Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence) position: , mismatch: 7, identity: 0.788

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
gatgggcagttagcttttgctggctgctctttt	Protospacer
 **.  * ******************..*****

304. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_018689 (Bacillus thuringiensis MC28 plasmid pMC429, complete sequence) position: , mismatch: 7, identity: 0.788

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
gatgagcagttagcttttgctggctgctctttt	Protospacer
 **.  * ******************..*****

305. spacer 2.10|1095881|34|CP035945|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 8, identity: 0.765

aatctttttccgtaaaatataaaggagtaagtat----	CRISPR spacer
aatctttttcagtaaaatctaaag----aatcatcacg	Protospacer
********** ******* *****    ** .**

306. spacer 2.10|1095881|34|CP035945|CRISPRCasFinder,CRT,PILER-CR matches to MH617217 (Microviridae sp. isolate ctda15, complete genome) position: , mismatch: 8, identity: 0.765

aatctttttccgtaaaatataaaggagtaagtat	CRISPR spacer
ataatttttgcataaaatataaaggagttgttat	Protospacer
*   ***** *.**************** . ***

307. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to JQ680370 (Unidentified phage clone 2204_scaffold812 genomic sequence) position: , mismatch: 8, identity: 0.733

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
taccggcggagagtgccagaacagtgccgc	Protospacer
   *. *.*********.***********

308. spacer 8.2|2947957|30|CP035945|CRISPRCasFinder matches to NC_047911 (Faecalibacterium phage FP_Lagaffe, complete genome) position: , mismatch: 8, identity: 0.733

acgcatcagagagtgccggaacagtgccgg	CRISPR spacer
taccggcggagagtgccagaacagtgccgc	Protospacer
   *. *.*********.***********

309. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034684 (Bacillus sp. BD59S plasmid pBTBD59S1, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

310. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009332 (Bacillus thuringiensis strain HD1011 plasmid 3, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

311. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

312. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

313. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

314. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053977 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

315. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

316. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031073 (Bacillus mycoides strain BPN401 plasmid pl50, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
ggtgagcagttagcttttgctggctgctctttt	Protospacer
 .*.  * ******************..*****

317. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_011777 (Bacillus cereus AH820 plasmid pAH820_272, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

318. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

319. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

320. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

321. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
attgagcagttagcttttgctagctgttctttt	Protospacer
  *.  * *************.*****.*****

322. spacer 2.1|1095290|34|CP035945|CRISPRCasFinder,CRT matches to MG710528 (Escherichia phage GER2, complete genome) position: , mismatch: 9, identity: 0.735

tttctgaatcactgtaagtaaaaatcacatcacc	CRISPR spacer
ctgattcttcattgtaagtaaaaattacatcatc	Protospacer
.*  *   ***.*************.******.*

323. spacer 2.7|1095683|34|CP035945|CRISPRCasFinder,CRT,PILER-CR matches to AP018478 (Mycobacterium phage A6 DNA, complete sequence) position: , mismatch: 9, identity: 0.735

tcatgggaactgccgtggcgacggcggaacagat	CRISPR spacer
tggggcgacctgccgtgacgacggcggaacccgt	Protospacer
* . * ** ********.************  .*

324. spacer 2.7|1095683|34|CP035945|CRISPRCasFinder,CRT,PILER-CR matches to AP018477 (Mycobacterium phage BK1 DNA, complete sequence) position: , mismatch: 9, identity: 0.735

tcatgggaactgccgtggcgacggcggaacagat	CRISPR spacer
tggggcgacctgccgtgacgacggcggaacccgt	Protospacer
* . * ** ********.************  .*

325. spacer 8.3|2948020|30|CP035945|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.7

cagtgccggaaagtgccggaagcgtatcag	CRISPR spacer
acacgccggaacgtgccggaatcgtattcc	Protospacer
  ..******* ********* *****.

326. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to CP037991 (Bacillus mycoides strain TH26 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
ttggagcagttagcttttgctagctgttctttt	Protospacer
.  .  * *************.*****.*****

327. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to MG584725 (Bacillus phage BVE2, complete genome) position: , mismatch: 9, identity: 0.727

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
agagagcagttagcttttgctagctgttctttt	Protospacer
 . .  * *************.*****.*****

328. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031644 (Bacillus anthracis strain MCCC 1A01412 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
accgagcagttagcttttgctagctgttctttt	Protospacer
  ..  * *************.*****.*****

329. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_010180 (Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence) position: , mismatch: 9, identity: 0.727

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
ttggagcagttagcttttgctagctgttctttt	Protospacer
.  .  * *************.*****.*****

330. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 9, identity: 0.727

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
actgagcagttagcttttgctggctgctctttg	Protospacer
  *.  * ******************..****

331. spacer 10.4|3862686|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 9, identity: 0.727

catcaagaacggagttgttacggcaagtgggac	CRISPR spacer
tatcaacaacggagttgttacagcaacgacccc	Protospacer
.***** **************.****  .   *

332. spacer 9.8|3566609|35|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 10, identity: 0.714

gccttaaaattgcagtaccatttaaagtgtttgaa	CRISPR spacer
gatttaaaattgcagtactttttaaagtacgacat	Protospacer
* .***************. ********..   *

333. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NC_011775 (Bacillus cereus G9842 plasmid pG9842_209, complete sequence) position: , mismatch: 10, identity: 0.697

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
gaggagaagttagcttttgctggctgctctttg	Protospacer
 * .    ******************..****

334. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to CP013001 (Bacillus thuringiensis strain XL6 plasmid, complete sequence) position: , mismatch: 10, identity: 0.697

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
gaggagaagttagcttttgctggctgctctttg	Protospacer
 * .    ******************..****

335. spacer 10.2|3862552|33|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

catattctgttagcttttgctggctgtcctttt	CRISPR spacer
accgagcagttagcttttgctagctgttctttg	Protospacer
  ..  * *************.*****.****

336. spacer 12.22|5393627|34|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to MF459647 (Erwinia phage vB_EamM_Joad, complete genome) position: , mismatch: 10, identity: 0.706

aaatgcaaaggacagcttttatgctgttactcca	CRISPR spacer
ttttttgaaggattgcttttatgctgttacttaa	Protospacer
   * ..*****. *****************. *

337. spacer 12.22|5393627|34|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to MF459646 (Erwinia phage vB_EamM_RisingSun, complete genome) position: , mismatch: 10, identity: 0.706

aaatgcaaaggacagcttttatgctgttactcca	CRISPR spacer
ttttttgaaggattgcttttatgctgttacttaa	Protospacer
   * ..*****. *****************. *

338. spacer 12.10|5392826|34|CP035945|PILER-CR,CRISPRCasFinder,CRT matches to MH632120 (Mycobacterium phage Thonko, complete genome) position: , mismatch: 12, identity: 0.647

ttatgcgctggtgctcggcttctgcacctaacaa	CRISPR spacer
gatcgcactggtgctcggcttctgcgccgcggtg	Protospacer
   .**.******************.**  .  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

28 : 18705

uncultured_Caudovirales_phage(37.5%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE94512.1\|28_1438_-	hypothetical protein	A0A2H4J4X1	uncultured_Caudovirales_phage	3.2e-204	71.8
QBE94513.1\|1430_2219_-	hypothetical protein	A0A2H4J6P5	uncultured_Caudovirales_phage	2.0e-70	56.3
QBE94514.1\|2281_2515_-	LexA repressor	A0A1B1P7Q3	Bacillus_phage	6.4e-09	46.3
QBE94515.1\|2966_3383_-	hypothetical protein	NA	NA	NA	NA
QBE94516.1\|3379_3649_-	hypothetical protein	NA	NA	NA	NA
QBE94517.1\|3651_3939_-	hypothetical protein	NA	NA	NA	NA
QBE94518.1\|3935_4127_-	Transcriptional repressor NrdR	NA	NA	NA	NA
QBE94519.1\|4123_4405_-	hypothetical protein	A0A2H4JD58	uncultured_Caudovirales_phage	4.7e-14	47.6
QBE94520.1\|4447_4672_-	hypothetical protein	NA	NA	NA	NA
QBE94521.1\|4806_4932_-	hypothetical protein	NA	NA	NA	NA
QBE94522.1\|4918_5509_-	hypothetical protein	A0A2H4JCJ0	uncultured_Caudovirales_phage	1.6e-43	52.1
QBE94523.1\|5569_5692_-	hypothetical protein	NA	NA	NA	NA
QBE94524.1\|5688_6036_-	hypothetical protein	NA	NA	NA	NA
QBE94525.1\|6039_6306_-	hypothetical protein	NA	NA	NA	NA
QBE94526.1\|6308_6929_-	hypothetical protein	A0A2H4J8I2	uncultured_Caudovirales_phage	1.5e-41	41.8
QBE94527.1\|6994_7276_-	hypothetical protein	NA	NA	NA	NA
QBE94528.1\|7285_7444_-	hypothetical protein	NA	NA	NA	NA
QBE94529.1\|7430_7760_-	hypothetical protein	NA	NA	NA	NA
QBE94530.1\|7761_8550_-	hypothetical protein	A0A2H4JF78	uncultured_Caudovirales_phage	2.8e-40	66.2
QBE94531.1\|8542_8938_-	hypothetical protein	U3PDU0	Lactobacillus_phage	3.1e-19	42.7
QBE94532.1\|9344_9653_-	hypothetical protein	NA	NA	NA	NA
QBE94533.1\|9653_10451_-	hypothetical protein	H7BV60	unidentified_phage	6.1e-75	53.5
QBE94534.1\|10447_11089_-	hypothetical protein	H2BD49	Pseudomonas_phage	6.9e-37	44.8
QBE94535.1\|11099_12530_-	Chromosome partition protein Smc	H7BUU2	unidentified_phage	7.0e-138	63.2
QBE94536.1\|12567_12873_-	hypothetical protein	NA	NA	NA	NA
QBE94537.1\|12869_13073_-	hypothetical protein	NA	NA	NA	NA
QBE94538.1\|13069_13210_-	hypothetical protein	NA	NA	NA	NA
QBE94539.1\|13222_13462_-	hypothetical protein	NA	NA	NA	NA
QBE94540.1\|13475_14249_-	hypothetical protein	A0A075KK42	Lactobacillus_phage	8.0e-80	59.2
QBE94541.1\|14245_14503_-	hypothetical protein	K4JXN9	Streptococcus_phage	2.1e-13	52.7
QBE94542.1\|14667_15168_+	hypothetical protein	A0A1X9H038	Staphylococcus_phage	7.3e-10	43.7
QBE94543.1\|15188_15662_+	hypothetical protein	B6SBW7	Clostridium_virus	1.3e-24	43.7
QBE94544.1\|15721_16456_+	hypothetical protein	NA	NA	NA	NA
QBE94545.1\|16723_17743_+	hypothetical protein	NA	NA	NA	NA
QBE94546.1\|18009_18705_+	7-carboxy-7-deazaguanine synthase	J9PV61	Bacillus_phage	4.7e-07	23.9

DBSCAN-SWA_2

790922 : 803728

Streptococcus_phage(54.55%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE95223.1\|790922_793712_-	hypothetical protein	A0A1X9I6B4	Streptococcus_phage	1.3e-60	50.5
QBE95224.1\|793712_794003_-	hypothetical protein	NA	NA	NA	NA
QBE95225.1\|794017_794464_-	hypothetical protein	NA	NA	NA	NA
QBE95226.1\|794463_795096_-	hypothetical protein	A0A1S5S9Y8	Streptococcus_phage	2.9e-27	37.2
QBE95227.1\|795098_795476_-	hypothetical protein	NA	NA	NA	NA
QBE95228.1\|795468_795945_-	hypothetical protein	R9QMA5	Lactococcus_phage	2.0e-09	34.5
QBE95229.1\|795934_796276_-	hypothetical protein	NA	NA	NA	NA
QBE95230.1\|796277_796805_-	hypothetical protein	A0A1S5SAD0	Streptococcus_phage	4.7e-23	40.5
QBE95231.1\|796824_797700_-	hypothetical protein	A0A141E1A1	Streptococcus_phage	1.0e-38	37.6
QBE95232.1\|797719_798340_-	hypothetical protein	A0A1S5SA01	Streptococcus_phage	1.5e-09	38.9
QBE95233.1\|798569_799529_-	NAD(+)--arginine ADP-ribosyltransferase EFV	NA	NA	NA	NA
QBE95234.1\|799482_800973_-	hypothetical protein	A0A1S5SAF3	Streptococcus_phage	2.5e-106	41.8
QBE95235.1\|800986_802369_-	hypothetical protein	C9E2I7	Enterococcus_phage	7.8e-187	68.9
QBE95236.1\|802361_803027_-	hypothetical protein	A0A2H4J6P5	uncultured_Caudovirales_phage	1.4e-16	68.0
QBE95237.1\|803084_803318_-	LexA repressor	A0A1B1P7Q3	Bacillus_phage	1.0e-06	41.8
QBE95238.1\|803404_803728_-	hypothetical protein	A0A0A8WIH8	Clostridium_phage	1.9e-19	44.4

DBSCAN-SWA_3

811072 : 816378

uncultured_marine_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE95252.1\|811072_811642_-	hypothetical protein	A0A0F7L7L4	uncultured_marine_virus	2.5e-14	50.6
QBE95253.1\|811760_812057_-	hypothetical protein	A0A075KJZ6	Lactobacillus_phage	1.7e-14	55.8
QBE95254.1\|812088_812508_-	hypothetical protein	NA	NA	NA	NA
QBE95255.1\|812552_813233_-	hypothetical protein	D7RWH3	Brochothrix_phage	1.7e-38	39.7
QBE95256.1\|813238_813940_-	hypothetical protein	A0A0E3Y6D2	Fusobacterium_phage	1.5e-24	38.5
QBE95257.1\|813936_814113_-	hypothetical protein	NA	NA	NA	NA
QBE95258.1\|814112_814298_-	hypothetical protein	NA	NA	NA	NA
QBE95259.1\|814343_814517_-	hypothetical protein	NA	NA	NA	NA
QBE95260.1\|814680_814917_-	hypothetical protein	NA	NA	NA	NA
QBE95261.1\|814919_815120_-	hypothetical protein	NA	NA	NA	NA
QBE95262.1\|815265_815574_-	hypothetical protein	NA	NA	NA	NA
QBE95263.1\|815578_815782_-	hypothetical protein	A0A0C5AC96	Paenibacillus_phage	3.6e-08	43.1
QBE95264.1\|816000_816378_+	HTH-type transcriptional regulator Xre	A0A1X9IGD3	Lactococcus_phage	2.1e-09	43.2

DBSCAN-SWA_4

2574232 : 2621162

Erysipelothrix_phage(91.11%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE96714.1\|2574232_2575819_+	hypothetical protein	A0A1B0RXB2	Streptococcus_phage	1.9e-19	26.7
QBE96715.1\|2576186_2576714_+	hypothetical protein	A0A2K5B267	Erysipelothrix_phage	2.0e-21	44.3
QBE96716.1\|2576778_2577561_+	hypothetical protein	A0A1Q1PVU2	Staphylococcus_phage	1.0e-66	51.0
QBE96717.1\|2577562_2577997_+	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	1.1e-65	82.6
QBE96718.1\|2577993_2580351_+	hypothetical protein	A0A1W6JQ82	Corynebacterium_phage	4.4e-246	52.5
QBE96719.1\|2580575_2580848_+	hypothetical protein	A0A2K5B272	Erysipelothrix_phage	1.1e-31	74.4
QBE96720.1\|2580837_2582190_+	hypothetical protein	A0A2K5B273	Erysipelothrix_phage	5.8e-195	83.4
QBE96721.1\|2582186_2582411_+	hypothetical protein	A0A2K5B274	Erysipelothrix_phage	2.0e-23	72.6
QBE96722.1\|2582407_2582860_+	hypothetical protein	A0A2K5B275	Erysipelothrix_phage	2.9e-50	68.8
QBE96723.1\|2583456_2583996_+	hypothetical protein	A0A2K5B277	Erysipelothrix_phage	2.8e-55	58.5
QBE96724.1\|2583997_2585161_+	S-adenosylmethionine synthase	A0A2K5B278	Erysipelothrix_phage	2.7e-148	68.0
QBE96725.1\|2585150_2586386_+	DNA adenine methyltransferase YhdJ	A0A2I4R670	Erysipelothrix_phage	1.1e-176	70.2
QBE96726.1\|2586488_2587178_+	hypothetical protein	A0A2K5B280	Erysipelothrix_phage	4.8e-60	54.2
QBE96727.1\|2587164_2587395_+	hypothetical protein	A0A2K5B281	Erysipelothrix_phage	1.6e-20	64.0
QBE96728.1\|2587384_2587564_+	hypothetical protein	NA	NA	NA	NA
QBE96729.1\|2587568_2587793_+	hypothetical protein	A0A2K5B284	Erysipelothrix_phage	3.5e-20	56.8
QBE96730.1\|2587941_2589507_+	hypothetical protein	A0A2K5B285	Erysipelothrix_phage	3.4e-263	83.0
QBE96731.1\|2589522_2590845_+	hypothetical protein	A0A2K5B287	Erysipelothrix_phage	3.0e-180	73.6
QBE96732.1\|2590900_2591512_+\|protease	ATP-dependent Clp protease proteolytic subunit 1	A0A1X9I749	Streptococcus_phage	1.2e-54	57.5
QBE96733.1\|2591528_2592725_+	hypothetical protein	A0A2I4R671	Erysipelothrix_phage	2.5e-109	52.5
QBE96734.1\|2592737_2592962_+	hypothetical protein	A0A2K5B289	Erysipelothrix_phage	1.6e-33	100.0
QBE96735.1\|2592984_2593293_+	hypothetical protein	A0A2K5B290	Erysipelothrix_phage	2.6e-50	96.1
QBE96736.1\|2593311_2593638_+	hypothetical protein	A0A2K5B291	Erysipelothrix_phage	5.6e-51	92.6
QBE96737.1\|2593624_2594056_+	hypothetical protein	A0A2K5B292	Erysipelothrix_phage	2.6e-72	98.6
QBE96738.1\|2594052_2594397_+	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	4.6e-56	96.5
QBE96739.1\|2594399_2594984_+	hypothetical protein	A0A2K5B294	Erysipelothrix_phage	2.0e-104	99.0
QBE96740.1\|2594997_2595381_+	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	1.4e-61	97.6
QBE96741.1\|2595586_2598193_+	Chromosome partition protein Smc	A0A2K5B297	Erysipelothrix_phage	5.1e-147	96.9
QBE96742.1\|2598205_2598982_+	hypothetical protein	A0A2I4R672	Erysipelothrix_phage	3.6e-141	95.3
QBE96743.1\|2598986_2601512_+	hypothetical protein	A0A2K5B298	Erysipelothrix_phage	0.0e+00	98.5
QBE96744.1\|2601714_2602299_+	hypothetical protein	A0A2K5B2A0	Erysipelothrix_phage	3.2e-105	96.9
QBE96745.1\|2602298_2604767_+	hypothetical protein	A0A2K5B2A1	Erysipelothrix_phage	0.0e+00	97.6
QBE96746.1\|2604827_2605238_+	hypothetical protein	A0A2K5B2A2	Erysipelothrix_phage	4.8e-68	98.5
QBE96747.1\|2605240_2606179_+	hypothetical protein	A0A2K5B2A3	Erysipelothrix_phage	5.5e-152	95.1
QBE96748.1\|2606996_2608916_+	Tetracycline resistance protein TetM from transposon TnFO1	A0A2K5B2A5	Erysipelothrix_phage	0.0e+00	99.7
QBE96749.1\|2609258_2609612_-	hypothetical protein	A0A2K5B2A6	Erysipelothrix_phage	7.6e-54	89.7
QBE96750.1\|2609892_2610111_+	hypothetical protein	A0A2I4R673	Erysipelothrix_phage	1.5e-31	97.2
QBE96751.1\|2610085_2610403_+	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	8.6e-49	98.1
QBE96752.1\|2610395_2611532_+	hypothetical protein	A0A2K5B2A8	Erysipelothrix_phage	1.2e-214	95.8
QBE96753.1\|2611537_2612089_+	hypothetical protein	A0A2K5B2A9	Erysipelothrix_phage	9.0e-102	100.0
QBE96754.1\|2612161_2614102_+	DNA polymerase I, thermostable	A0A2K5B2B0	Erysipelothrix_phage	0.0e+00	94.0
QBE96755.1\|2614157_2614373_+	hypothetical protein	A0A2K5B2B1	Erysipelothrix_phage	1.2e-30	93.0
QBE96756.1\|2614434_2615997_+	Transposon gamma-delta resolvase	A0A2K5B2B2	Erysipelothrix_phage	7.0e-293	97.7
QBE96757.1\|2615997_2616414_+	hypothetical protein	A0A2K5B2B3	Erysipelothrix_phage	1.1e-72	100.0
QBE96758.1\|2616415_2617978_+	Transposon gamma-delta resolvase	A0A2K5B2B4	Erysipelothrix_phage	8.1e-265	93.5
QBE96759.1\|2618155_2619409_-	hypothetical protein	NA	NA	NA	NA
QBE96760.1\|2619944_2621162_+	putative MFS-type transporter	A0A2K5B2B5	Erysipelothrix_phage	1.6e-215	99.8

DBSCAN-SWA_5

3478161 : 3486159

Agrobacterium_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE97505.1\|3478161_3478743_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	8.7e-55	57.2
QBE97506.1\|3478823_3480119_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.8e-130	54.9
QBE97507.1\|3480148_3482464_+\|protease	Lon protease 1	A0A0R6PGP8	Moraxella_phage	6.1e-168	43.2
QBE97508.1\|3482486_3483080_+	putative GTP-binding protein EngB	NA	NA	NA	NA
QBE97509.1\|3483182_3484367_+	Fructose-1-phosphate phosphatase YqaB	M1I080	Acanthocystis_turfacea_Chlorella_virus	7.3e-16	28.2
QBE97510.1\|3484465_3485311_+	Energy-coupling factor transporter ATP-binding protein EcfA1	G9BWD6	Planktothrix_phage	2.2e-22	32.8
QBE97511.1\|3485301_3486159_+	Energy-coupling factor transporter ATP-binding protein EcfA2	A0A2H4PQG7	Staphylococcus_phage	3.2e-13	29.4

DBSCAN-SWA_6

3818004 : 3829009

uncultured_Mediterranean_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE97798.1\|3818004_3820239_+	hypothetical protein	A0A1B1IVP7	uncultured_Mediterranean_phage	2.9e-21	32.7
QBE97799.1\|3820340_3822056_+	Single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.9e-79	30.3
QBE97800.1\|3822157_3822682_+	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.7e-23	41.1
QBE97801.1\|3822699_3825009_+	GTP pyrophosphokinase	A0A1B1IUF0	uncultured_Mediterranean_phage	6.2e-11	36.7
QBE97802.1\|3825023_3825656_+	putative metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	4.3e-31	36.4
QBE97803.1\|3825680_3827195_+	Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ	NA	NA	NA	NA
QBE97804.1\|3827166_3827715_+	Cyclic di-GMP phosphodiesterase response regulator RpfG	NA	NA	NA	NA
QBE97805.1\|3827761_3829009_+\|tRNA	Histidine--tRNA ligase	A0A2K9L0H9	Tupanvirus	3.0e-36	29.8

DBSCAN-SWA_7

5024334 : 5054175

Clostridium_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE98894.1\|5024334_5025360_-	Peptidoglycan endopeptidase RipA	A0A222YYN6	Bacillus_phage	6.3e-40	49.4
QBE98895.1\|5025372_5027406_-	hypothetical protein	NA	NA	NA	NA
QBE98896.1\|5027410_5027767_-	hypothetical protein	NA	NA	NA	NA
QBE98897.1\|5027767_5030488_-	hypothetical protein	A0A2H4J4V9	uncultured_Caudovirales_phage	1.4e-83	39.8
QBE98898.1\|5030494_5030734_-	hypothetical protein	M9Q2I4	Clostridium_phage	1.5e-13	47.2
QBE98899.1\|5030828_5031125_-	hypothetical protein	NA	NA	NA	NA
QBE98900.1\|5031124_5031571_-	hypothetical protein	M9Q1I1	Clostridium_phage	2.6e-27	43.7
QBE98901.1\|5031579_5031972_-	hypothetical protein	M9Q2F6	Clostridium_phage	3.4e-18	42.7
QBE98902.1\|5031974_5032358_-	hypothetical protein	M9Q249	Clostridium_phage	1.4e-13	37.8
QBE98903.1\|5032354_5032690_-	hypothetical protein	NA	NA	NA	NA
QBE98904.1\|5032694_5033087_-	hypothetical protein	NA	NA	NA	NA
QBE98905.1\|5033079_5033358_-	hypothetical protein	NA	NA	NA	NA
QBE98906.1\|5033369_5034254_-	hypothetical protein	M9Q2F4	Clostridium_phage	1.2e-103	64.8
QBE98907.1\|5034273_5034903_-	hypothetical protein	NA	NA	NA	NA
QBE98908.1\|5034940_5035291_-	hypothetical protein	NA	NA	NA	NA
QBE98909.1\|5035324_5035456_-	hypothetical protein	NA	NA	NA	NA
QBE98910.1\|5035502_5037203_-	hypothetical protein	M9Q2F2	Clostridium_phage	8.2e-61	37.1
QBE98911.1\|5037298_5038909_-	hypothetical protein	M9Q246	Clostridium_phage	1.9e-120	45.8
QBE98912.1\|5038913_5040353_-	hypothetical protein	A0A090EUA8	Clostridium_phage	1.2e-145	57.1
QBE98913.1\|5040318_5040723_-	hypothetical protein	Q9AYX3	Lactococcus_phage	6.9e-35	51.7
QBE98914.1\|5040801_5041545_-	hypothetical protein	NA	NA	NA	NA
QBE98915.1\|5041972_5042389_-	hypothetical protein	NA	NA	NA	NA
QBE98916.1\|5042395_5042683_-	hypothetical protein	NA	NA	NA	NA
QBE98917.1\|5042679_5042874_-	Transcriptional repressor NrdR	NA	NA	NA	NA
QBE98918.1\|5042870_5043152_-	hypothetical protein	A0A2H4JD58	uncultured_Caudovirales_phage	2.2e-16	51.2
QBE98919.1\|5043220_5043343_-	hypothetical protein	NA	NA	NA	NA
QBE98920.1\|5043339_5044536_-	hypothetical protein	A0A2H4JC51	uncultured_Caudovirales_phage	2.1e-159	66.3
QBE98921.1\|5044662_5044893_-	hypothetical protein	NA	NA	NA	NA
QBE98922.1\|5044885_5045224_-	hypothetical protein	NA	NA	NA	NA
QBE98923.1\|5045220_5045664_-	LexA repressor	NA	NA	NA	NA
QBE98924.1\|5045679_5046111_-	hypothetical protein	NA	NA	NA	NA
QBE98925.1\|5046112_5046832_-	hypothetical protein	A0A0F7L6H0	uncultured_marine_virus	3.9e-28	38.5
QBE98926.1\|5046788_5047055_-	hypothetical protein	A0A2H4J4U3	uncultured_Caudovirales_phage	3.6e-16	44.7
QBE98927.1\|5047017_5047389_-	hypothetical protein	NA	NA	NA	NA
QBE98928.1\|5047433_5048117_-	hypothetical protein	D7RWH3	Brochothrix_phage	6.4e-33	40.8
QBE98929.1\|5048117_5048741_-	hypothetical protein	NA	NA	NA	NA
QBE98930.1\|5048724_5048913_-	hypothetical protein	NA	NA	NA	NA
QBE98931.1\|5048909_5049095_-	hypothetical protein	NA	NA	NA	NA
QBE98932.1\|5049107_5049365_-	hypothetical protein	NA	NA	NA	NA
QBE98933.1\|5049345_5049534_-	hypothetical protein	NA	NA	NA	NA
QBE98934.1\|5049560_5049707_-	hypothetical protein	NA	NA	NA	NA
QBE98935.1\|5049738_5049945_-	hypothetical protein	A0A059T6G1	Listeria_phage	2.1e-08	46.6
QBE98936.1\|5050196_5050598_+	HTH-type transcriptional regulator ImmR	Q5YAA4	Bacillus_phage	4.3e-21	40.7
QBE98937.1\|5050604_5051027_+	Metallopeptidase ImmA	Q0H245	Geobacillus_phage	9.5e-19	37.0
QBE98938.1\|5051045_5052500_+	hypothetical protein	X5JAC1	Clostridium_phage	1.0e-35	52.6
QBE98939.1\|5052441_5054175_+	hypothetical protein	I3VYZ3	Thermoanaerobacterium_phage	9.9e-30	26.7

DBSCAN-SWA_8

6301351 : 6324385

Clostridium_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBE99991.1\|6301351_6304462_-	hypothetical protein	M9Q251	Clostridium_phage	1.5e-52	33.6
QBE99992.1\|6304495_6304714_-	hypothetical protein	M9Q2I4	Clostridium_phage	9.9e-12	50.0
QBE99993.1\|6304821_6305166_-	hypothetical protein	M9Q2L0	Clostridium_phage	9.8e-14	44.4
QBE99994.1\|6305176_6305626_-	hypothetical protein	M9Q1I1	Clostridium_phage	2.7e-56	70.5
QBE99995.1\|6305629_6306019_-	hypothetical protein	M9Q2F6	Clostridium_phage	2.4e-32	49.2
QBE99996.1\|6306015_6306396_-	hypothetical protein	M9Q249	Clostridium_phage	6.1e-33	57.9
QBE99997.1\|6306395_6306734_-	hypothetical protein	NA	NA	NA	NA
QBE99998.1\|6306738_6307122_-	hypothetical protein	M9Q2K9	Clostridium_phage	5.8e-15	37.5
QBE99999.1\|6307123_6307402_-	hypothetical protein	M9Q1H8	Clostridium_phage	4.6e-06	52.0
QBF00001.1\|6307403_6308315_-	hypothetical protein	M9Q2F4	Clostridium_phage	1.3e-124	71.8
QBF00002.1\|6308329_6308977_-	hypothetical protein	NA	NA	NA	NA
QBF00003.1\|6309246_6309492_-	hypothetical protein	NA	NA	NA	NA
QBF00004.1\|6309448_6311335_-	hypothetical protein	M9Q2F2	Clostridium_phage	2.3e-96	41.2
QBF00005.1\|6311337_6312888_-	hypothetical protein	M9Q246	Clostridium_phage	6.0e-127	47.2
QBF00006.1\|6312884_6314249_-	hypothetical protein	M9Q2I1	Clostridium_phage	5.2e-159	58.3
QBF00007.1\|6314248_6314692_-	hypothetical protein	NA	NA	NA	NA
QBF00008.1\|6314780_6315200_-	hypothetical protein	NA	NA	NA	NA
QBF00009.1\|6315196_6315475_-	hypothetical protein	NA	NA	NA	NA
QBF00010.1\|6315471_6315660_-	hypothetical protein	NA	NA	NA	NA
QBF00011.1\|6315659_6315821_-	hypothetical protein	NA	NA	NA	NA
QBF00012.1\|6315838_6316048_-	hypothetical protein	NA	NA	NA	NA
QBF00013.1\|6316158_6316719_-	hypothetical protein	NA	NA	NA	NA
QBF00014.1\|6316715_6316940_-	hypothetical protein	NA	NA	NA	NA
QBF00015.1\|6316936_6317332_-	hypothetical protein	A0A2I7SC39	Paenibacillus_phage	2.7e-44	64.9
QBF00016.1\|6317655_6319893_-	hypothetical protein	A0A0K2CZ75	Paenibacillus_phage	4.2e-291	65.8
QBF00017.1\|6319895_6321479_-	Putative DNA repair helicase RadD	A0A0K2CZF8	Paenibacillus_phage	1.0e-243	77.8
QBF00018.1\|6321490_6321931_-	hypothetical protein	A0A2I7SC41	Paenibacillus_phage	1.7e-26	45.1
QBF00019.1\|6321942_6323094_-	hypothetical protein	A0A0K2CZH1	Paenibacillus_phage	1.4e-125	59.5
QBF00020.1\|6323095_6324385_-	DNA replication and repair protein RecF	A0A097BY67	Enterococcus_phage	2.8e-154	64.8

DBSCAN-SWA_9

6337465 : 6354836

uncultured_Caudovirales_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QBF00041.1\|6337465_6342172_-	hypothetical protein	A0A0N9BA91	Vibrio_phage	1.3e-39	41.3
QBF00042.1\|6342176_6342536_-	hypothetical protein	V9QIZ3	Oenococcus_phage	2.4e-10	34.8
QBF00043.1\|6342545_6346076_-	hypothetical protein	A0A1B3B0K6	Gordonia_phage	4.7e-18	45.0
QBF00044.1\|6346111_6346312_-	hypothetical protein	NA	NA	NA	NA
QBF00045.1\|6346308_6346449_-	hypothetical protein	NA	NA	NA	NA
QBF00046.1\|6346479_6346941_-	hypothetical protein	A0A1X9I685	Streptococcus_phage	3.8e-13	38.1
QBF00047.1\|6346955_6347381_-	hypothetical protein	A0A1X9I6R2	Streptococcus_phage	5.6e-35	52.6
QBF00048.1\|6347397_6347757_-	hypothetical protein	A0A2H4JDU4	uncultured_Caudovirales_phage	2.2e-32	59.5
QBF00049.1\|6347753_6348293_-	hypothetical protein	A0A1S5S809	Streptococcus_phage	4.0e-22	38.3
QBF00050.1\|6348289_6348664_-	hypothetical protein	A0A2H4J6Q5	uncultured_Caudovirales_phage	7.6e-28	52.8
QBF00051.1\|6348635_6348959_-	hypothetical protein	A0A2H4JD74	uncultured_Caudovirales_phage	1.6e-34	70.2
QBF00052.1\|6348972_6350010_-	hypothetical protein	A0A1J1J8Y4	Escherichia_phage	4.2e-52	36.2
QBF00053.1\|6350027_6350717_-	hypothetical protein	A0A2H4J4U9	uncultured_Caudovirales_phage	5.0e-41	65.2
QBF00054.1\|6350945_6351338_-	hypothetical protein	A0A1S5SA89	Streptococcus_phage	5.3e-32	53.8
QBF00055.1\|6351354_6351636_-	hypothetical protein	A0A0A8WEQ1	Clostridium_phage	4.0e-13	47.8
QBF00056.1\|6351712_6351889_-	hypothetical protein	NA	NA	NA	NA
QBF00057.1\|6351889_6353464_-	NAD(+)--arginine ADP-ribosyltransferase EFV	A0A2H4J4W7	uncultured_Caudovirales_phage	2.4e-107	55.8
QBF00058.1\|6353453_6354836_-	hypothetical protein	A0A2H4JDT5	uncultured_Caudovirales_phage	9.6e-185	71.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP035945

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection