CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP025691	Lactobacillus plantarum strain IRG1 plasmid pIRG101, complete sequence	0 crisprs	csa3	0	0	0
CP025692	Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence	0 crisprs	NA	0	0	0
CP025694	Lactobacillus plantarum strain IRG1 plasmid pIRG104, complete sequence	0 crisprs	NA	0	0	0
CP025690	Lactobacillus plantarum strain IRG1 chromosome, complete genome	1 crisprs	WYL,csa3,cas9,cas2,csn2,DinG,cas3,DEDDh	1	7	6
CP025695	Lactobacillus plantarum strain IRG1 plasmid pIRG105, complete sequence	0 crisprs	NA	0	0	0
CP025693	Lactobacillus plantarum strain IRG1 plasmid pIRG103, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP025690_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025690_1

138924-139817

TypeII

Consensus_repeat	Method
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	PILER-CR

13 spacers

csn2,cas2,cas9

The CRISPR arrays of CP025690_1

>merge|CP025690|1|138924-139817|CRISPRCasFinder,CRT,PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTAAAGTTCTATGCAACGCTGACCTAATATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAGGATCATTCAGATGGGTACGCTTAACATGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTAAACGTGTATTCTTTGACCGTGACATTGGTCTTGAATAGTAGTCATATCAAACAGGTTTGGAACCACGTTTATACTTTACTAACGGCCGTGGCGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTATCTAGCAACCGGCCCGGCAAGCAATACGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATGTCACTGGACGCCCTCCCAAGCCCGTAGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTAAGTAAGATGCGTGCGTGTGACGCAGCGAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCTGAGTCTAAAGCTAAAGAGGCCCGGAGTGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGGACTTGGCGGATGCATTCTGGCGTGACCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAGATTGAAGCTAACAAGCGGTTGGCATTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTCAGGGACATGTTGACCGGACTCGTGGCCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTTCGAACTTTGAGGATAACACAGAGTATGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGATGCTGAGGAAACGAAGCATAGAACGTTTGTCTTGAATAGTGGCCACATCAAAAACAGTTTCACG

>CP025690|1|1|138924-139817|CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAAAGTTCTATGCAACGCTGACCTAATAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATCATTCAGATGGGTACGCTTAACATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAAACGTGTATTCTTTGACCGTGACATTG
GTCTTGAATAGTAGTCATATCAAACAGGTTTGGAAC	CACGTTTATACTTTACTAACGGCCGTGGCG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TATCTAGCAACCGGCCCGGCAAGCAATACG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATGTCACTGGACGCCCTCCCAAGCCCGTAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAAGTAAGATGCGTGCGTGTGACGCAGCGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTGAGTCTAAAGCTAAAGAGGCCCGGAGTG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGGACTTGGCGGATGCATTCTGGCGTGACC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAGATTGAAGCTAACAAGCGGTTGGCATTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTCAGGGACATGTTGACCGGACTCGTGGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTTCGAACTTTGAGGATAACACAGAGTATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GATGCTGAGGAAACGAAGCATAGAACGTTT
GTCTTGAATAGTGGCCACATCAAAAACAGTTTCACG

>CP025690|1|1|138924-139817|CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAAAGTTCTATGCAACGCTGACCTAATAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATCATTCAGATGGGTACGCTTAACATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAAACGTGTATTCTTTGACCGTGACATTG
GTCTTGAATAGTAGTCATATCAAACAGGTTTGGAAC	CACGTTTATACTTTACTAACGGCCGTGGCG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TATCTAGCAACCGGCCCGGCAAGCAATACG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATGTCACTGGACGCCCTCCCAAGCCCGTAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAAGTAAGATGCGTGCGTGTGACGCAGCGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTGAGTCTAAAGCTAAAGAGGCCCGGAGTG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGGACTTGGCGGATGCATTCTGGCGTGACC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAGATTGAAGCTAACAAGCGGTTGGCATTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTCAGGGACATGTTGACCGGACTCGTGGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTTCGAACTTTGAGGATAACACAGAGTATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GATGCTGAGGAAACGAAGCATAGAACGTTT
GTCTTGAATAGTGGCCACATCAAAAACAGTTTCACG

>CP025690|1|1|139056-139751|PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAAACGTGTATTCTTTGACCGTGACATTG
GTCTTGAATAGTAGTCATATCAAACAGGTTTGGAAC	CACGTTTATACTTTACTAACGGCCGTGGCG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TATCTAGCAACCGGCCCGGCAAGCAATACG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATGTCACTGGACGCCCTCCCAAGCCCGTAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAAGTAAGATGCGTGCGTGTGACGCAGCGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTGAGTCTAAAGCTAAAGAGGCCCGGAGTG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGGACTTGGCGGATGCATTCTGGCGTGACC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAGATTGAAGCTAACAAGCGGTTGGCATTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTCAGGGACATGTTGACCGGACTCGTGGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTTCGAACTTTGAGGATAACACAGAGTATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP025690.1\|QAA27225.1\|128785_129256_-\|ADP-ribose-pyrophosphatase	unknown	unknown	gnl\|CDD\|240033
CP025690.1\|QAA27240.1\|150365_150632_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	unknown
CP025690.1\|QAA27233.1\|141645_144384_-\|magnesium-transporting-ATPase	unknown	unknown	gnl\|CDD\|319775
CP025690.1\|QAA27234.1\|144782_144977_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
CP025690.1\|QAA27235.1\|145042_145645_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
CP025690.1\|QAA27224.1\|127077_128670_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|214906
CP025690.1\|QAA27231.1\|138221_138899_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
CP025690.1\|QAA27226.1\|129488_130853_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
CP025690.1\|QAA27239.1\|147904_150100_+\|peptide-cleavage/export-ABC-transporter	unknown	unknown	gnl\|CDD\|130261
CP025690.1\|QAA27228.1\|131684_132467_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP025690.1\|QAA27238.1\|146887_147313_-\|DUF3021-domain-containing-protein	unknown	unknown	gnl\|CDD\|378668
CP025690.1\|QAA27230.1\|137919_138225_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
CP025690.1\|QAA27229.1\|132755_136832_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
CP025690.1\|QAA27236.1\|145758_146232_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP025690.1\|QAA27222.1\|124813_126013_+\|putative-hydroxymethylpyrimidine-transporter-CytX	unknown	unknown	gnl\|CDD\|274096
CP025690.1\|QAA27227.1\|130952_131660_+\|hypothetical-protein	unknown	unknown	unknown
CP025690.1\|QAA27223.1\|126094_126835_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase	unknown	unknown	gnl\|CDD\|224982
CP025690.1\|QAA27232.1\|139978_141649_+\|DDE-transposase	unknown	unknown	gnl\|CDD\|226192
CP025690.1\|QAA27237.1\|146377_146800_+\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
CP025690.1\|QAA27241.1\|150635_150848_+\|transposase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP025690.1\|QAA27225.1\|128785_129256_-\|ADP-ribose-pyrophosphatase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.32043e-57
CP025690.1\|QAA27233.1\|141645_144384_-\|magnesium-transporting-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP025690.1\|QAA27234.1\|144782_144977_-\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	2.12668e-17
CP025690.1\|QAA27235.1\|145042_145645_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	3.18179e-31
CP025690.1\|QAA27224.1\|127077_128670_+\|DNA-binding-protein	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	1.88552e-17
CP025690.1\|QAA27231.1\|138221_138899_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.97852e-80
CP025690.1\|QAA27239.1\|147904_150100_+\|peptide-cleavage/export-ABC-transporter	gnl\|CDD\|130261	TIGR01193, transport/processing_ATP-binding_protein, ABC-type bacteriocin transporter. This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other].	0
CP025690.1\|QAA27228.1\|131684_132467_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.86408e-25
CP025690.1\|QAA27238.1\|146887_147313_-\|DUF3021-domain-containing-protein	gnl\|CDD\|378668	pfam11457, DUF3021, Protein of unknown function (DUF3021). This is a bacterial family of uncharacterized proteins.	9.90209e-24
CP025690.1\|QAA27230.1\|137919_138225_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	5.63184e-25
CP025690.1\|QAA27229.1\|132755_136832_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	7.18651e-129
CP025690.1\|QAA27236.1\|145758_146232_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	0.000122978
CP025690.1\|QAA27222.1\|124813_126013_+\|putative-hydroxymethylpyrimidine-transporter-CytX	gnl\|CDD\|274096	TIGR02358, purine-cytosine_transport_protein, putative hydroxymethylpyrimidine transporter CytX. On the basis of a phylogenomic study of thiamine biosythetic, salvage, and transporter genes and a highly conserved RNA element THI, this protein family has been identified as a probable transporter of hydroxymethylpyrimidine (HMP), the phosphorylated (by ThiD) form of which gets joined (by ThiE) to hydroxyethylthiazole phosphate to make thiamine phosphate. [Transport and binding proteins, Nucleosides, purines and pyrimidines, Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	2.26192e-147
CP025690.1\|QAA27226.1\|129488_130853_+\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
CP025690.1\|QAA27223.1\|126094_126835_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase	gnl\|CDD\|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	7.45143e-88
CP025690.1\|QAA27232.1\|139978_141649_+\|DDE-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.21465e-14
CP025690.1\|QAA27237.1\|146377_146800_+\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	2.47416e-43

>CP025690.1|QAA27231.1|138221_138899_+|type-II-A-CRISPR-associated-protein-Csn2
MNITYYPFPPFKIDAGKVNVLDLGNSNMYAEVCQGFRNRIDSVRISNDDLELQTMSSQCNWYGDLMLSVDLNRLFLKKVQTQIIKLMADDRQVAVLDENRKVVSQVMEASFLLDLPLDVDESPSLEQILKFTGIHFPTELMNDPRAILEALVQTHVELGLKQKLVLTNISHYLDQKQWASFEQLVHDLGATVIVIEYSEINRMEKFKNSCYYYVDEDSVDWRDMN
>CP025690.1|QAA27230.1|137919_138225_+|CRISPR-associated-endonuclease-Cas2
MRLIVMFDVPMDTSEERRAYQHFHKALVREGFLMMQYSTYVRVCVNKKAAEFVEKRIAPLAPKGGKVQTMTVTEKQYQAMHYIQGTPSNDVLNSAERTIVI
>CP025690.1|QAA27229.1|132755_136832_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKEPYGVGLDIGTNSVGWTVVDASGHVRKIKGQTGIGVRLFKEGAAAADRRGFRTTRRRLKRVKWRLRLLREFFDQPISKVDINFFARRKYSDISPRDPNYNGLEKTLFNDRSDQDFYHDYPTIYHLREALMTQHRKFDVREIYLAIHHIVKYRGNFLRNDAATAYRSGTLDLQQHFETLNHLFSQADLELNLNLTTDVALLDSIKQTLVRTDISRSDRQKLIMPLLAVLTGATTAEKKRQKAVVTEFAKALVGNKTKIDVLTLTDIDATEAKDWAFSLEENQDKLPGIEDRFSEVGQQIIDEVIRLYASVNLAQLIPEGKRFSQSMVEKYKRHGEDLKLLKAYIRSQSDAKRGRAIRATYDQYIDGVKSKQVTQEAFQKALGKFVDADVDLNSWAAQIKQAIDSEQFMPKLRTKQNGAIPYQVQQNELDQIISNQKEYYPWLGEENPVIKRRGKFPYKLDELVGFRVPYYVGPLITKEMQAATANAGFAWMVRKADGPITPWNFDDKVDRVASATAFIQRMQTTDTYLIGEEVLPARSLIYQRFMVLNELNNIRVDDGQLTPRQKQRLYNQVFKKHKRVTAKNIQDNLVAAGEFPTAPRITGLADPKVFNSSLSTYHDLKQVLPEAMSDVRKQADIEKIILWSTIFEDSTIFKQKLTEISWLTAAQLKQLGQLRYRGWGQLSRKLLTGLKDDNNRSIMDGLWETNANFMQLRSQPAIENQIKSANQANLTTADLQDTINELYTSPQNKKAIREVMVVLADIKDAMHGQTPNWIFVEAARGGGVAGRRTQSRSKQIVAAYQGTAQAIVRDQVQRELKEKIKNKANFNTRLVLYFLQNGRDLYTGDAINIDRLSEYDIDHILPQSLVKDDSLDNRVLTNARINREKNDTFASEKFGKKMGAKWKEMHRMGLMTKRKLDHLLMRPDEISKYATGFINRQLVETRQVIKLVEELINAEYPSTAIVSVKANLTHQFRQTFDFPKIREVNDYHHAFDAALTAFIGTYLLKRYPKLERFFVYGKFAKQPVNLTRFNVIRKLAKTDTPITDIDTGEVLWDKLTDIKYFETLYDYKRLLVTREVSENYGAMFDQTLLKASDNGKRLIRKKQSFDTAIYGGYTGKTLAYMAIVKVSTKKDVQYQVVGVPTTMVTQIEQLEQQGMTNKQAVTKVIEPLIAANNKKMLTYEVLLPKVRFEQVVRDRIKGQTHRFTLGTDTYYHNIQELYLPLTLQRAFLGKQNESEVQLNQNLLTVFDATLAQVNRYFPLYEMNKFKKILNSARDQIELLEAKNQFVKNKLVLGKQGILTNMFIGLHANASYGDLKVLGVKTDFGKLQVPGGIKLTGDAEIIYQSPTGLFERKISLKDL
>CP025690.1|QAA27228.1|131684_132467_+|alpha/beta-hydrolase
MHFITSDHVQLDYTDEGQGQPIVILTGFGGAKDIWRAQIPVLIQAGYQVINLDGRCQGLSEHTAKGLRMSRRAVDAHELIEKLQLEQPILLGNSMGAATWFAYVSLYGDTGIKALIDVDQTPRMINTPHWQYGFKQVQWQDIPDYFRMPLGHSTFKHIDDATYARVKAVEAQAPFDAKLMFPLLVNHAVQDWRDVIRQLTVPFLIIAGAKSPFFNPDFAAVTAQMALRGQSVVIPEAGHIVMAEQSAAFNKALLEFLATC
>CP025690.1|QAA27227.1|130952_131660_+|hypothetical-protein
MVKQGHYAKVSKQKRLRQLKQRRQAQEKRAIMPEMVSEFLQVRYHLTQAAKQRPAMRQMMQRFMAQWLAAGQAELSDNGQTTWSVVALTKQTLQTFNRQLPWQGYALVDQEMARWTAFLNKEVPAVPLSERITLTEALSPATWQACLSEQLAINALLALTGDSRQLGQITTEQVRQLQNSIQTATGIDWEKVAQLLDSTVIAQNTLSEAGLDDKTRQWLEKLQKLTPQDFNNHIE
>CP025690.1|QAA27226.1|129488_130853_+|amino-acid-permease
MQRKLSTGQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLIAYIVSGAFLYLIMRALGEMLYVDPNTGSFAKFASEYIHPVFGYLTAWSNIFQFVVVGMSEMIALGGYCRYWWPNLPDWIPGLIAIVFLCAANLISVKMFGTLETWFSLIKVVTIILMIIAGLGLIIFGIGNGGHPIGISNLWTHGGFFTGGVKGFVFALAIVLASYQGIELIGVTAGEAENPQSTIVKAIRSTVARILIFYVGAIFVIVSIYPWDKLSQIGSPFVQTFAKIGITAAASIINFVVITASLSGTNSGIYSASRMTYTLAESHQLPRKMTLLNRHGVPFYSVIAIATGILIGVVLNVVLPMFFKDASEIFVMVYSSSVLPGMVPWFVILVSQIAFRKQNAAKMANHPFKMPLSPYSNYLTLAFLALTLVFMFINPETRYSILVGVVFLVIMTLIYFRKYAGNKEETL
>CP025690.1|QAA27225.1|128785_129256_-|ADP-ribose-pyrophosphatase
MANYIKEIRALVGHKPIILNTAAGILVNDQQQVLLNLRTDTHNWSLPGGYLEYGETYATACLREYKEDSGIDVEVVDRIGIFDKGETAYPNGDVAQTISALFLVKPIGGHVLTQATDETLKLDYFDFDNLPPLLNQQNADMIHAAQEYLQTHSATK
>CP025690.1|QAA27224.1|127077_128670_+|DNA-binding-protein
MERIEAGMSVMTLKKQTYRVIAVINQGQELLVRAHEPETADIEIIPVTTVVQVTEQNSTDDAAVALDTVTVVGERYVDDIVATLTTLRVGMAVLLQRESGNQYDDNAISVWTLQHAKLGYIARYQNQPYATLMDQGQRLYGIVTVLDQQKQHLELMLWRTTAVPSPIEALQIRQRLAKPRTNLGAVPTHSLQTPLGTIVMMCNGHPIKYQQVPLSPWLTPADELHVTKRYLLTPDWSQVPPDSLITCQVTAKADVVQRWQNEHISAAVLTNASSFYVVGISAQTKTGLNDNLVDDAAQPAVIYRVGQVSAHMQAGFMVSWAPFGDPRVQPALKLALHFSSQPLVPYHPVTPSRTNATFTQQELAALLVSALPNYQGGQRLEPSVTTITVEKLRQTLGDQTYHALANYQRHVQLVAGSTEGVNETLLQALIHAVTYHELTTMHYYQPTVGMVDQVIYPIQLFSTTTKDEDDAQLVGCLALYNYETFEIQQVPLTAIARIAIIADPEHPQTTPETESPDWLRIFLHGWNDGF
>CP025690.1|QAA27223.1|126094_126835_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase
MVKPIIGIAPGVVTVNSQMFPGRVRDYVNRDYLKSVTDNGGVPLVLPVTTDATTIERYVGMIDGLLLCGGADVAPLTYGEEPQPKLGGVDPERDQYEIALIRATHAVGKPVLGICRGLQILNVCYGGNLYQDMSELPAGQGTLKHMQGQLAAYGMHHVKVVPGTTLAEYLGTTSDAIAINSFHHQAVKQVATGFQVVAQSADQVVEAIEATAGGLQLGVQWHPEMMQQVNSMQARLFAAFVRACVA
>CP025690.1|QAA27222.1|124813_126013_+|putative-hydroxymethylpyrimidine-transporter-CytX
MKHDGIFRSQFLLWLGAAISIAEILTGTLMAPLGLTRGLAAIVLGHLIGCGLFLVPAGYLGAKLHQSALASAQLAFGRGGVLLASGLNALQLVGWTAVMIVNAQLAMNSISGKLFGFRSPLLMATIVAILIIAWLLMGSQLLFKINNAVVGLLVLGTVLMLVMVFMAPTTSQSVSPTSMTFGQAVELNVTMALSWLPLIGDYTQRVDRPLPVALVSAGGYMLGSLVMFVTGLLVVLRTGQTDITALLTRSGLGLVALLIIVFSTVTTTFLDTYSAATSLANLTGSRYVNRLAVGVTVVGLLIALTVAMTYYQNFLYLIGSVFTPLYAIIFVTYFVRHATLPYWLNFCWWVVGIVAYYQLQAIDFIGGTTLLVLVGLSIAVWLTGIIVKPTELEYRELSH
>CP025690.1|QAA27232.1|139978_141649_+|DDE-transposase
MQDYYNMNQTTLSIALDYQPEEHHPARYINQLVESLKLKYDYQFGRPREYNLGAMLKLVLLAYCYGIFSSRKIEQFARENKPAGWLIADQIPSYRTICRFRISDELATLTTDSLSQLTQYLRQNGMIDDVSFIDGTKILADANKYSFVWKKNTIRFDKMNREKLVDLLGELHEAKIVGEIPAGSELTPELLDIMISKVEDHLVVLNETVEATKQVSPNPAKQQRRTVKSQKRKLDKRRDKMREHQAQQAIYDQRNSYSKTDHDATFMRVKEDPMQNGQLKPAYNVQIATSNQFITGYRLFQNPTDTRTLQPFIEHLKANNVLGHTIVADAGYGSESNYRYLEDEFGQHTVLIPYGTMLKENSRKWQSDDRKVMNWDYHEKDDYFINPQNVRFNFNAYRQRTDKYGFTRDFKEYIAEKYDENHQLISAALTPKGYLKRISVNENWEYFKSKQRELLSAPETGQIYAQRKIDVEPVFGKMKASLHFNRFSVRGFDKVTKEAGIVILALNIMKLVTVGTSFKNQRRKQMGRETKIRFLVPFTYTEASYVTASFYLLTNY
>CP025690.1|QAA27233.1|141645_144384_-|magnesium-transporting-ATPase
MIKDDNQSLTSNEEQNDTQNPPDADNLWQLDESALAAKYATDPENGLSTAEAAERLQHNGRNELETKRTSRFVQFIKQFNNSIIYILAAAAVLTFFMHHYSDSIVIGLVIIANAIIGYVQERQAGNALERIREMLISKNFVIRDGKKLEIDARELVVGDLVNLEAGDAVPADMRLISADNFNVQESVLTGETNPVEKQEEPITETTPALADRKNMVYASTAVTSGSAVGIVTATAEDTEIGHIQQSVSDVKQTTTPLMRNLNSLGVGLSIAIVVAAVLLFLLGMVMDTYSLPTLLIAVITMVVGSMPEGLPASTSVVLAMGTRQMTKKNVIVKSLPAVETLGAVDIVNTDKTGTLTKNEMTVTKVVTPEHTFDVTGVGYDDNGGVNFDGHLKLNGNKVDWHQDNAMEWLVKIAGQTTDAELHFENNRWELTGEPTDGALTTLYRKMTGHDPEVEEVDSLPFDSAFRFSARLADLDGQRLLMVKGSPATVLRLTDQANQTAYWDDAMDDLTADGLRVVALAYQEVDDDVTTIDAQAIGGLHLAGLVGIIDPPREEAATAIAELRQAGVQVKMITGDHPDTAMAIANKLNLAANVKAITGPEIDAMDDQQLQARIDDYNVFARATPNNKLRIVRAQQANNHVVSMTGDGVNDAPALKQADIGVAMGIKGTEVAKESADMVLADDDFADIVAAVREGRHVFDNIRKTIRFLLPTSFAEGLVVIISILMGHELPLYPTQLLWINMVSALTIQFAFIFEPPEAGIMARGPRNVKSGLLSKLDYFEIGYVSFLISGLGIFAYNYLTALGLPNVVGSTMSLNIIIFGKIFYLFNLRNDHPVISKYFFQNKMAFYIIGILILLQLGIIYLPFMQSVFHTTSINFWYGWGIPIICGIVVLIVTEVGKFIRFRWMGKDGVID
>CP025690.1|QAA27234.1|144782_144977_-|PspC-domain-containing-protein
MKIDIHRSATDRVIAGVIGGIAEHFNWNTNVTRLLFVVLAITPMFPGIIAYLILWLLMKDPIKD
>CP025690.1|QAA27235.1|145042_145645_-|NADPH-dependent-oxidoreductase
MFKIAIILGSTRSQANGRALFNHLKLIIDQLPTHSTIHYQFLDLANYQLPLFDEPEPPMANPHRELPANQQQWLTDMASADGYIILTPEYNHAMPAGLKNAFDFLAFEGARKPAKIISYSDNMRGGQFGAAALVPVLQRLGMVVLPKPTPIGNVPQTLQSNGHFIDNAPLSKRYDHALHQALTEITYYTTVLTTTPFPTD
>CP025690.1|QAA27236.1|145758_146232_+|MarR-family-transcriptional-regulator
MTTPLVSQLMTELNQFLTQDSVDDQEKRWAMQQTIDPQLQAALKQLSTTDIKIIAYLGRRGASRAKSLPAPTELSQATISRGLTKLSRLKLATKYRDLTNNKEILVRLTTLGEAVADLHTQLDAAIAAKAQAIADDYSDAELRRFVSLMRRIREIKI
>CP025690.1|QAA27237.1|146377_146800_+|Hsp20/alpha-crystallin-family-protein
MANTLMNRNDFGMLDPFERMARSFWAPLENMDQVLKTDINETDDQYQVKVDVPGIDKQDVKLDYRDNVLSIKVQKDSFVDHEDQDQNIVMNERHTGTLQRQYMLPNVAADKITASQADGVLTITLPKTQPSANDGQIEIQ
>CP025690.1|QAA27238.1|146887_147313_-|DUF3021-domain-containing-protein
MSIKKTGLRYLMALGFSTFFNTTYLFPSNPTFVSHWSSPLAATQLSTLLWILIGEVWAFSSWLFEIETWSITKQTIAHCLCSYLGMTPLAILCGWFPLNVRWFGFYTLVYTGAYIGLWLIEMALARIKVIQLNQQLTNQRS
>CP025690.1|QAA27239.1|147904_150100_+|peptide-cleavage/export-ABC-transporter
MEFKNNYVEQLDETDCGAATLAMILKYYKSDVSLALLRKYAQTDKDGTTGLGMIKAAEHFGLATEAIKYDTEAIKYDTEQLEQLESKLKYPFIAHVNKGEGLLHYVVVISCDNNTVHIADPDSKIKIAKLTLTEFSTMWSGIAFFMWPSSHYKKQSLGTSSLLNTAKILLTQKKLIVGIIVFMTLSTFITIGGTFYLEKIVDEYIPKHEVNQLSVLGLVLIAAYVFHGLFSYIEGLWSAILGKNLSNTVLSDYLNHLLKLPIAFFDTRQSGELTSRFSDASSIISALSATAITTLLNVGTIAIISFVLLFISVRLFLIALVIVPIYAAIIAFFAPRFNRWNNDRMEKNATVSSQIIEDLHGIETIKTLSIEEKMYRSFTKNFSNLLNADFTYNKLDVIQEALKDLAGLIINLSVLYLGALLVLSDQISLGELVAFTALFSYFLNPIQEIINLQNEIQTASVANKRLSEIMSEPTEIIGQSQPELTATDDNSDAIQFKNVEFEYKYGQPVLHDINLTVKQNQSTAIIGLSGSGKTTLAKLLIDFYKPTAGQILINGHDIDHYNKHTLRTYIGYLSQTPHIFTGSIFENIALGHKGASLADVRWAAQIAQIDDDIMAMPERYETKLTEESGLSGGQLQRLAIARTILKRTPIMILDESTSNLDLETEKKILINIRKLDGVTVIFIAHRLQVTTQADNIIVMKNGFIIENGSRQTLEQQRGTYYQLLADFQSFD
>CP025690.1|QAA27240.1|150365_150632_+|helix-turn-helix-domain-containing-protein
MFSAKIKQQVLSKYLQENSPLLPMKKYDIKGSATIYQWPTQFEILGIQGLENCHRKTFYEYSFKIKVIKWRQEHHASYPVTATHFRLK
>CP025690.1|QAA27241.1|150635_150848_+|transposase
MMFWDWERRLIEGRLKPAKGRSLKLTDKSKQSKTLKQLQEENELLRIRVAYLEKLEVLAQKKSQTKKRPS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP025690_2	2.1\|2514984\|26\|CP025690\|PILER-CR	2514984-2515009	26	CP025690.1	2514900-2514925	0	1.0

1. spacer 2.1|2514984|26|CP025690|PILER-CR matches to position: 2514900-2514925, mismatch: 0, identity: 1.0

cattcaatgttccaagcccattagta	CRISPR spacer
cattcaatgttccaagcccattagta	Protospacer
**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025690_1	1.3\|139092\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139092-139121	30	MG788324	Lactobacillus phage PM411, complete genome	31503-31532	0	1.0
CP025690_1	1.10\|139554\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139554-139583	30	MG788324	Lactobacillus phage PM411, complete genome	18394-18423	0	1.0
CP025690_1	1.10\|139554\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139554-139583	30	NZ_CP024415	Lactobacillus plantarum strain ATCC 8014 plasmid pLP39, complete sequence	29329-29358	0	1.0
CP025690_1	1.10\|139554\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139554-139583	30	NZ_CP018210	Lactobacillus plantarum strain BLS41 plasmid pLPBLS41_1, complete sequence	9497-9526	1	0.967
CP025690_1	1.3\|139092\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139092-139121	30	NZ_CP024415	Lactobacillus plantarum strain ATCC 8014 plasmid pLP39, complete sequence	18018-18047	2	0.933
CP025690_1	1.3\|139092\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139092-139121	30	NZ_CP018210	Lactobacillus plantarum strain BLS41 plasmid pLPBLS41_1, complete sequence	36587-36616	2	0.933
CP025690_1	1.5\|139224\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139224-139253	30	X90511	Lactobacillus bacteriophage phig1e DNA for Rorf162, Holin, Lysin, and Rorf175 genes	2482-2511	2	0.933
CP025690_1	1.5\|139224\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139224-139253	30	NC_004305	Lactobacillus phage phig1e, complete genome	7338-7367	2	0.933
CP025690_1	1.5\|139224\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139224-139253	30	X98106	Lactobacillus bacteriophage phig1e complete genomic DNA	7338-7367	2	0.933
CP025690_1	1.1\|138960\|30\|CP025690\|CRISPRCasFinder,CRT	138960-138989	30	JX486087	Lactobacillus phage ATCC 8014-B1, complete genome	28509-28538	4	0.867
CP025690_1	1.1\|138960\|30\|CP025690\|CRISPRCasFinder,CRT	138960-138989	30	JN051154	Pediococcus phage clP1, complete genome	16773-16802	4	0.867
CP025690_1	1.7\|139356\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139356-139385	30	NZ_CP046030	Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence	20170-20199	4	0.867
CP025690_2	2.1\|2514984\|26\|CP025690\|PILER-CR	2514984-2515009	26	AP014283	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C59, * SEQUENCING IN PROGRESS *	15532-15557	4	0.846
CP025690_1	1.5\|139224\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139224-139253	30	NZ_CP011920	Burkholderia cenocepacia strain ST32 plasmid pBCEN1232, complete sequence	79143-79172	6	0.8
CP025690_1	1.5\|139224\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139224-139253	30	NZ_CP044333	Methylocystis parvus strain BRCS2 plasmid unnamed2, complete sequence	131307-131336	7	0.767
CP025690_1	1.7\|139356\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139356-139385	30	KC292026	Halovirus HGTV-1, complete genome	52332-52361	7	0.767
CP025690_1	1.10\|139554\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139554-139583	30	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	232868-232897	7	0.767
CP025690_1	1.8\|139422\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139422-139451	30	MN694430	Marine virus AFVG_250M44, complete genome	21949-21978	9	0.7
CP025690_1	1.8\|139422\|30\|CP025690\|CRISPRCasFinder,CRT,PILER-CR	139422-139451	30	MN692992	Marine virus AFVG_117M93, complete genome	21941-21970	9	0.7

1. spacer 1.3|139092|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to MG788324 (Lactobacillus phage PM411, complete genome) position: , mismatch: 0, identity: 1.0

ttaaacgtgtattctttgaccgtgacattg	CRISPR spacer
ttaaacgtgtattctttgaccgtgacattg	Protospacer
******************************

2. spacer 1.10|139554|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to MG788324 (Lactobacillus phage PM411, complete genome) position: , mismatch: 0, identity: 1.0

aagattgaagctaacaagcggttggcatta	CRISPR spacer
aagattgaagctaacaagcggttggcatta	Protospacer
******************************

3. spacer 1.10|139554|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024415 (Lactobacillus plantarum strain ATCC 8014 plasmid pLP39, complete sequence) position: , mismatch: 0, identity: 1.0

aagattgaagctaacaagcggttggcatta	CRISPR spacer
aagattgaagctaacaagcggttggcatta	Protospacer
******************************

4. spacer 1.10|139554|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018210 (Lactobacillus plantarum strain BLS41 plasmid pLPBLS41_1, complete sequence) position: , mismatch: 1, identity: 0.967

aagattgaagctaacaagcggttggcatta	CRISPR spacer
aagattgaggctaacaagcggttggcatta	Protospacer
********.*********************

5. spacer 1.3|139092|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024415 (Lactobacillus plantarum strain ATCC 8014 plasmid pLP39, complete sequence) position: , mismatch: 2, identity: 0.933

ttaaacgtgtattctttgaccgtgacattg	CRISPR spacer
ttaaacgtgtattctttgactgtgacgttg	Protospacer
********************.*****.***

6. spacer 1.3|139092|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018210 (Lactobacillus plantarum strain BLS41 plasmid pLPBLS41_1, complete sequence) position: , mismatch: 2, identity: 0.933

ttaaacgtgtattctttgaccgtgacattg	CRISPR spacer
ttaaacgtgtattctttgactgtgacgttg	Protospacer
********************.*****.***

7. spacer 1.5|139224|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to X90511 (Lactobacillus bacteriophage phig1e DNA for Rorf162, Holin, Lysin, and Rorf175 genes) position: , mismatch: 2, identity: 0.933

tatctagcaaccggcccggcaagcaatacg	CRISPR spacer
tatctagcaaccggcccatcaagcaatacg	Protospacer
*****************. ***********

8. spacer 1.5|139224|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NC_004305 (Lactobacillus phage phig1e, complete genome) position: , mismatch: 2, identity: 0.933

tatctagcaaccggcccggcaagcaatacg	CRISPR spacer
tatctagcaaccggcccatcaagcaatacg	Protospacer
*****************. ***********

9. spacer 1.5|139224|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to X98106 (Lactobacillus bacteriophage phig1e complete genomic DNA) position: , mismatch: 2, identity: 0.933

tatctagcaaccggcccggcaagcaatacg	CRISPR spacer
tatctagcaaccggcccatcaagcaatacg	Protospacer
*****************. ***********

10. spacer 1.1|138960|30|CP025690|CRISPRCasFinder,CRT matches to JX486087 (Lactobacillus phage ATCC 8014-B1, complete genome) position: , mismatch: 4, identity: 0.867

ttaaagttctatgcaacgctgacctaatat	CRISPR spacer
ttaaggtgctatgcaacgctgacctaatca	Protospacer
****.** ********************

11. spacer 1.1|138960|30|CP025690|CRISPRCasFinder,CRT matches to JN051154 (Pediococcus phage clP1, complete genome) position: , mismatch: 4, identity: 0.867

ttaaagttctatgcaacgctgacctaatat	CRISPR spacer
ttaaggtgctatgcaacgctgacctaatca	Protospacer
****.** ********************

12. spacer 1.7|139356|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046030 (Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.867

taagtaagatgcgtgcgtgtgacgcagcga	CRISPR spacer
taaataagatgtgtgcgtgtgacgcagggc	Protospacer
***.*******.*************** *

13. spacer 2.1|2514984|26|CP025690|PILER-CR matches to AP014283 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C59, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 4, identity: 0.846

cattcaatgttccaagcccattagta	CRISPR spacer
cattaaatgttccatgcccattaaaa	Protospacer
**** ********* ********. *

14. spacer 1.5|139224|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011920 (Burkholderia cenocepacia strain ST32 plasmid pBCEN1232, complete sequence) position: , mismatch: 6, identity: 0.8

tatctagcaaccggcccggcaagcaatacg	CRISPR spacer
tcgctgtcaaccggcctggcaagcaacacg	Protospacer
*  **. *********.*********.***

15. spacer 1.5|139224|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044333 (Methylocystis parvus strain BRCS2 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

tatctagcaaccggcccggcaagcaatacg	CRISPR spacer
ttcgaaccaagcggcccggcgagcaatacg	Protospacer
* .  * *** *********.*********

16. spacer 1.7|139356|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to KC292026 (Halovirus HGTV-1, complete genome) position: , mismatch: 7, identity: 0.767

taagtaagatgcgtgcgtgtgacgcagcga	CRISPR spacer
aaagtaagatgcgtgcctgtcacgcacgag	Protospacer
 *************** *** *****  ..

17. spacer 1.10|139554|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 7, identity: 0.767

aagattgaagctaacaagcggttggcatta	CRISPR spacer
agtgaagaagcgaacaagcggctggcatta	Protospacer
*. .  ***** *********.********

18. spacer 1.8|139422|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to MN694430 (Marine virus AFVG_250M44, complete genome) position: , mismatch: 9, identity: 0.7

ctgagtctaaagctaaagaggcccggagtg	CRISPR spacer
ggatgtctaaagataaagagacccggacaa	Protospacer
  . ******** *******.******  .

19. spacer 1.8|139422|30|CP025690|CRISPRCasFinder,CRT,PILER-CR matches to MN692992 (Marine virus AFVG_117M93, complete genome) position: , mismatch: 9, identity: 0.7

ctgagtctaaagctaaagaggcccggagtg	CRISPR spacer
ggatgtctaaagataaagagacccggacaa	Protospacer
  . ******** *******.******  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

37655 : 64165

Lactococcus_phage(16.67%)

tail,terminase,portal,head,capsid,protease,integrase

attL 60520:60558|attR 69205:69243

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAA27134.1\|37655_38810_-\|integrase	site-specific integrase	A0A172LN96	Lactococcus_phage	6.1e-60	36.7
QAA27135.1\|38888_39533_-	transcriptional regulator	NA	NA	NA	NA
QAA27136.1\|39680_39860_+	helix-turn-helix domain-containing protein	E9LUT5	Lactobacillus_phage	4.3e-21	87.9
QAA27137.1\|39902_40010_+	hypothetical protein	NA	NA	NA	NA
QAA27138.1\|40130_40385_+	hypothetical protein	NA	NA	NA	NA
QAA27139.1\|40381_41182_+	DNA replication protein	NA	NA	NA	NA
QAA27140.1\|41181_42576_+	virulence protein	Q4ZD27	Staphylococcus_phage	1.2e-70	35.7
QAA27141.1\|42719_43139_+	hypothetical protein	NA	NA	NA	NA
QAA27142.1\|43162_43345_+	DUF2758 domain-containing protein	NA	NA	NA	NA
QAA27143.1\|43354_43696_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
QAA27144.1\|43688_44078_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	1.0e-19	45.2
QAA27145.1\|44770_45244_+\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
QAA27146.1\|45240_46944_+\|terminase	terminase	A0A2H4JBN3	uncultured_Caudovirales_phage	2.2e-122	41.1
QAA27147.1\|46897_47098_+	hypothetical protein	NA	NA	NA	NA
QAA27148.1\|47098_48205_+\|portal	phage portal protein	A0A2H4J9Q5	uncultured_Caudovirales_phage	7.2e-50	33.3
QAA27149.1\|48194_49775_+\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	7.4e-40	26.5
QAA27150.1\|50184_50451_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
QAA27151.1\|50586_50955_+	hypothetical protein	NA	NA	NA	NA
QAA27152.1\|51087_51288_+	cold-shock protein	Q9AZD3	Lactococcus_phage	4.8e-21	73.0
QAA27153.1\|51374_51596_+	hypothetical protein	NA	NA	NA	NA
QAA27154.1\|52209_52917_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.9e-44	40.1
QAA27155.1\|52930_54805_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	5.5e-34	31.8
QAA27156.1\|54785_56111_+	hypothetical protein	NA	NA	NA	NA
QAA27157.1\|56122_56977_+	regulator	NA	NA	NA	NA
QAA27158.1\|57335_58151_+	MBL fold metallo-hydrolase	A0A0D3MKU5	Leuconostoc_phage	2.8e-11	28.0
QAA27159.1\|58261_59524_+\|protease	serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	2.3e-15	28.8
QAA27160.1\|60078_60558_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
60520:60558	attL	NA	NA	NA	NA
QAA27161.1\|60631_61957_+	hypothetical protein	NA	NA	NA	NA
QAA27162.1\|61961_62447_+	hypothetical protein	NA	NA	NA	NA
QAA27163.1\|63268_64165_-\|integrase	integrase	NA	NA	NA	NA
69205:69243	attR	NA	NA	NA	NA

DBSCAN-SWA_2

345359 : 460464

108

Tupanvirus(13.33%)

bacteriocin,transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAA27414.1\|345359_347015_+\|transposase	DDE transposase	A0ZS58	Staphylococcus_virus	6.0e-93	41.5
QAA27415.1\|347032_348199_-	hypothetical protein	NA	NA	NA	NA
QAA27416.1\|348793_349609_+	ABC transporter permease	NA	NA	NA	NA
QAA27417.1\|349621_350713_+	teichoic acids export ATP-binding protein TagH	A0A2H4PQG7	Staphylococcus_phage	7.2e-18	29.7
QAA27418.1\|351091_351364_+	hypothetical protein	NA	NA	NA	NA
QAA27419.1\|351590_352133_+	PadR family transcriptional regulator	NA	NA	NA	NA
QAA27420.1\|352129_353575_+	MFS transporter	NA	NA	NA	NA
QAA27421.1\|353904_355221_-	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	3.3e-33	29.6
QAA27422.1\|355715_356675_+	L-lactate dehydrogenase	NA	NA	NA	NA
QAA27423.1\|356777_357047_+	hypothetical protein	NA	NA	NA	NA
QAA27424.1\|357276_357840_-	peptidase M10	NA	NA	NA	NA
QAA27425.1\|358033_358702_+	ribose 5-phosphate isomerase A	NA	NA	NA	NA
QAA27426.1\|358859_360365_+	copper oxidase	NA	NA	NA	NA
QAA27427.1\|360629_360998_+	DUF1304 domain-containing protein	NA	NA	NA	NA
QAA27428.1\|361110_361620_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
QAA27429.1\|361650_362847_-	DUF2075 domain-containing protein	NA	NA	NA	NA
QAA27430.1\|362956_363427_+	transcriptional regulator	NA	NA	NA	NA
QAA27431.1\|363445_363901_+	hypothetical protein	NA	NA	NA	NA
QAA27432.1\|364004_364577_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
QAA27433.1\|364742_365663_-	ribonucleoside hydrolase RihC	NA	NA	NA	NA
QAA27434.1\|365799_366711_+	oxidoreductase	NA	NA	NA	NA
QAA27435.1\|367600_368047_-	ribonuclease H	NA	NA	NA	NA
QAA27436.1\|368284_369811_+	glycine/betaine ABC transporter permease	NA	NA	NA	NA
QAA27437.1\|369811_370783_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.7
QAA27438.1\|370860_372192_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
QAA27439.1\|372657_374175_+	glycerol kinase	NA	NA	NA	NA
QAA27440.1\|374189_376019_+	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
QAA27441.1\|376033_376756_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	4.1e-30	31.9
QAA27442.1\|376950_379311_+	cell surface protein precursor	NA	NA	NA	NA
QAA27443.1\|381147_381456_+	hypothetical protein	NA	NA	NA	NA
QAA27444.1\|381872_382151_+	hypothetical protein	NA	NA	NA	NA
QAA27445.1\|382454_383372_+	hypothetical protein	NA	NA	NA	NA
QAA27446.1\|383415_383679_+	hypothetical protein	NA	NA	NA	NA
QAA27447.1\|383790_384069_+	hypothetical protein	NA	NA	NA	NA
QAA27448.1\|384450_385068_-	sugar O-acetyltransferase	NA	NA	NA	NA
QAA27449.1\|385071_386226_-	MFS transporter	NA	NA	NA	NA
QAA27450.1\|386229_387021_-	HAD family hydrolase	NA	NA	NA	NA
QAA27451.1\|387091_387964_-	AraC family transcriptional regulator	NA	NA	NA	NA
QAA27452.1\|388123_388939_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
QAA27453.1\|389464_390841_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
QAA27454.1\|390885_392070_+	cation:proton antiporter	NA	NA	NA	NA
QAA27455.1\|392454_392658_+	hypothetical protein	NA	NA	NA	NA
QAA27456.1\|392892_393045_-	hypothetical protein	NA	NA	NA	NA
QAA27457.1\|393069_393738_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
QAA27458.1\|393734_393908_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnK	NA	NA	NA	NA
QAA27459.1\|393938_394106_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnJ	NA	NA	NA	NA
QAA27460.1\|394967_395168_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
QAA27461.1\|395295_395463_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
QAA27462.1\|395580_396780_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
QAA27463.1\|396810_397557_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA27464.1\|397910_398099_+	pirin	NA	NA	NA	NA
QAA27465.1\|398434_398581_+\|bacteriocin	bacteriocin plantaricin-A	NA	NA	NA	NA
QAA27466.1\|398771_400100_+	two-component system sensor histidine kinase DcuS	NA	NA	NA	NA
QAA27467.1\|400100_400844_+	DNA-binding response regulator	NA	NA	NA	NA
QAA27468.1\|400962_401706_+	DNA-binding response regulator	NA	NA	NA	NA
QAA27469.1\|402011_402785_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA27470.1\|402883_403042_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA
QAA27471.1\|403066_403237_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnE	NA	NA	NA	NA
QAA27472.1\|403503_405654_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	6.1e-45	27.9
QAA27473.1\|405669_407046_+	HlyD family secretion protein	NA	NA	NA	NA
QAA27474.1\|407135_407825_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA27475.1\|407892_408561_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA27476.1\|408647_409328_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA27477.1\|409421_410108_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA27478.1\|410223_410511_+	hypothetical protein	NA	NA	NA	NA
QAA27479.1\|410522_410816_+	addiction module antidote protein, HigA family	M9MUN2	Rhodococcus_phage	9.9e-07	48.3
QAA27480.1\|411105_413415_-	ATP-dependent DNA helicase	NA	NA	NA	NA
QAA27481.1\|413673_414450_+	amidohydrolase	NA	NA	NA	NA
QAA27482.1\|414889_415906_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
QAA27483.1\|416311_417022_+	GntR family transcriptional regulator	NA	NA	NA	NA
QAA27484.1\|417094_418456_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
QAA27485.1\|418462_418651_+	hypothetical protein	NA	NA	NA	NA
QAA27486.1\|418640_419063_+	DUF3284 domain-containing protein	NA	NA	NA	NA
QAA30006.1\|419285_420641_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
QAA27487.1\|420658_422095_+	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	9.7e-31	25.5
QAA27488.1\|422215_423112_+	ROK family protein	NA	NA	NA	NA
QAA27489.1\|423261_424008_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
QAA27490.1\|424120_425134_+\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
QAA27491.1\|425576_426494_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
QAA27492.1\|426539_427814_+	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
QAA27493.1\|427806_428766_+	IpaB/EvcA family protein	NA	NA	NA	NA
QAA27494.1\|428787_429492_+	NAD-dependent protein deacylase	NA	NA	NA	NA
QAA27495.1\|429491_430334_+	DUF72 domain-containing protein	NA	NA	NA	NA
QAA27496.1\|430930_431320_+	phosphohydrolase	NA	NA	NA	NA
QAA27497.1\|431641_433693_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	2.7e-90	35.8
QAA27498.1\|434179_434554_+	hypothetical protein	NA	NA	NA	NA
QAA27499.1\|434834_436019_+	MFS transporter	NA	NA	NA	NA
QAA27500.1\|436141_436918_+	TatD family deoxyribonuclease	NA	NA	NA	NA
QAA27501.1\|436904_437468_+	ribonuclease M5	NA	NA	NA	NA
QAA27502.1\|437464_438355_+	ribosomal RNA small subunit methyltransferase A	NA	NA	NA	NA
QAA27503.1\|438459_438711_+	hypothetical protein	NA	NA	NA	NA
QAA27504.1\|438843_439710_+	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	NA	NA	NA	NA
QAA27505.1\|440019_440964_+	acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit	NA	NA	NA	NA
QAA27506.1\|441230_441929_+	ABC transporter ATP-binding protein	A0A1V0SGN0	Hokovirus	1.2e-15	27.8
QAA27507.1\|441915_442719_+	metal ABC transporter permease	NA	NA	NA	NA
QAA27508.1\|444356_444620_+	hypothetical protein	NA	NA	NA	NA
QAA27509.1\|445112_445949_+	pur operon repressor	NA	NA	NA	NA
QAA27510.1\|446017_447400_+	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L140	Tupanvirus	5.7e-28	33.2
QAA27511.1\|448824_449805_+	ribose-phosphate pyrophosphokinase 1	A0A2K9L8D8	Tupanvirus	4.9e-42	36.3
QAA27512.1\|450094_451117_+	YdcF family protein	NA	NA	NA	NA
QAA27513.1\|451199_452186_+	lipoprotein	NA	NA	NA	NA
QAA27514.1\|452355_453165_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
QAA27515.1\|453184_454537_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	5.2e-26	32.9
QAA27516.1\|454551_455484_-	lipoate--protein ligase family protein	NA	NA	NA	NA
QAA27517.1\|455846_456287_+	DUF1934 domain-containing protein	NA	NA	NA	NA
QAA27518.1\|456331_456940_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
QAA27519.1\|457112_458726_+	CTP synthetase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.2e-143	49.9
QAA27520.1\|459192_460464_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.5e-96	43.7

DBSCAN-SWA_3

1204836 : 1273766

Lactobacillus_phage(82.05%)

tail,holin,tRNA,terminase,portal,head,capsid,protease,integrase

attL 1210548:1210564|attR 1252164:1252180

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAA30024.1\|1204836_1205502_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
QAA28160.1\|1206194_1206674_-	MarR family transcriptional regulator	NA	NA	NA	NA
QAA28161.1\|1206787_1207300_-	hypothetical protein	NA	NA	NA	NA
QAA28162.1\|1207414_1207702_+	hypothetical protein	NA	NA	NA	NA
QAA28163.1\|1207763_1210034_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	5.2e-119	31.5
1210548:1210564	attL	NA	NA	NA	NA
QAA28164.1\|1210680_1211817_-\|integrase	site-specific integrase	E9LUS1	Lactobacillus_phage	1.2e-212	98.9
QAA28165.1\|1211930_1212272_+	hypothetical protein	NA	NA	NA	NA
QAA28166.1\|1212347_1212806_+	DUF4065 domain-containing protein	NA	NA	NA	NA
QAA28167.1\|1212795_1213200_+	hypothetical protein	NA	NA	NA	NA
QAA28168.1\|1213406_1213865_-	hypothetical protein	NA	NA	NA	NA
QAA28169.1\|1214531_1214732_-	hypothetical protein	E9LUS6	Lactobacillus_phage	4.9e-26	100.0
QAA30025.1\|1214796_1215186_-	ImmA/IrrE family metallo-endopeptidase	D6PSS8	Lactobacillus_phage	4.6e-36	54.3
QAA28170.1\|1215216_1215543_-	XRE family transcriptional regulator	A0A1B0Y2R0	Lactobacillus_phage	6.9e-17	44.1
QAA28171.1\|1215798_1216014_+	hypothetical protein	NA	NA	NA	NA
QAA28172.1\|1216099_1216327_+	zinc-ribbon domain-containing protein	NA	NA	NA	NA
QAA28173.1\|1216800_1217544_+	hypothetical protein	A0A1P8BM06	Lactococcus_phage	9.7e-51	44.9
QAA28174.1\|1217557_1217740_+	hypothetical protein	NA	NA	NA	NA
QAA28175.1\|1217707_1218427_-	hypothetical protein	NA	NA	NA	NA
QAA28176.1\|1218519_1218849_+	DUF771 domain-containing protein	E9LUT3	Lactobacillus_phage	4.4e-48	81.7
QAA28177.1\|1218938_1219193_+	hypothetical protein	NA	NA	NA	NA
QAA28178.1\|1219195_1219426_+	hypothetical protein	E9LUT8	Lactobacillus_phage	1.3e-22	78.1
QAA28179.1\|1219639_1219945_+	hypothetical protein	NA	NA	NA	NA
QAA28180.1\|1219964_1220657_+	hypothetical protein	E9LUU3	Lactobacillus_phage	1.5e-117	88.7
QAA28181.1\|1220706_1221504_+	replication protein	Q9AZA0	Lactobacillus_prophage	1.3e-53	68.9
QAA28182.1\|1221503_1222289_+	DNA replication protein	E9LUN6	Lactobacillus_phage	3.5e-131	90.8
QAA28183.1\|1222816_1223308_+	methyltransferase domain-containing protein	O03918	Lactobacillus_phage	1.2e-84	89.9
QAA30026.1\|1223539_1223935_+	hypothetical protein	A0A2P0ZKS9	Lactobacillus_phage	8.3e-33	57.1
QAA28184.1\|1224279_1224705_+	transcriptional regulator	E9LUP5	Lactobacillus_phage	7.7e-61	79.4
QAA28185.1\|1225127_1225745_+	hypothetical protein	Q20DE2	Lactobacillus_phage	7.8e-54	49.0
QAA28186.1\|1225816_1226020_+	hypothetical protein	NA	NA	NA	NA
QAA28187.1\|1226066_1226246_+	hypothetical protein	E9LUP6	Lactobacillus_phage	8.6e-14	71.2
QAA28188.1\|1226214_1226727_+	HNH endonuclease	E9LUP7	Lactobacillus_phage	6.6e-83	93.6
QAA28189.1\|1226947_1227409_+\|terminase	phage terminase small subunit P27 family	A0A286QRF4	Streptococcus_phage	6.5e-45	58.2
QAA30027.1\|1227395_1229303_+	hypothetical protein	E9LUP9	Lactobacillus_phage	9.8e-180	49.7
QAA28190.1\|1229292_1229487_+	DUF1056 domain-containing protein	E9LUQ0	Lactobacillus_phage	2.0e-24	92.2
QAA28191.1\|1229489_1230686_+\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	1.5e-205	89.7
QAA28192.1\|1230663_1231452_+	peptidase	E9LUQ2	Lactobacillus_phage	1.2e-123	89.7
QAA28193.1\|1231451_1232684_+\|capsid	phage major capsid protein	E9LUQ3	Lactobacillus_phage	1.9e-200	87.7
QAA28194.1\|1232756_1233095_+\|head,tail	phage gp6-like head-tail connector protein	E9LUQ4	Lactobacillus_phage	7.0e-57	100.0
QAA28195.1\|1233078_1233441_+\|head,tail	head-tail adaptor protein	E9LUQ5	Lactobacillus_phage	1.5e-65	99.2
QAA28196.1\|1233430_1233871_+\|tail	phage tail protein	E9LUQ6	Lactobacillus_phage	3.2e-78	97.9
QAA28197.1\|1233867_1234251_+	hypothetical protein	E9LUQ7	Lactobacillus_phage	1.0e-64	96.9
QAA28198.1\|1234251_1234890_+\|tail	phage tail protein	E9LUQ8	Lactobacillus_phage	3.7e-107	92.9
QAA28199.1\|1235091_1235475_+	hypothetical protein	E9LUQ9	Lactobacillus_phage	3.9e-64	100.0
QAA28200.1\|1235471_1235663_+	hypothetical protein	E9LUR0	Lactobacillus_phage	1.5e-27	100.0
QAA28201.1\|1235675_1240610_+\|tail	phage tail protein	E9LUR1	Lactobacillus_phage	0.0e+00	83.0
QAA28202.1\|1240681_1242457_+\|tail	phage tail protein	A0A2P0ZLH2	Lactobacillus_phage	1.5e-299	89.3
QAA28203.1\|1242523_1244938_+	hypothetical protein	A0A2P0ZLF8	Lactobacillus_phage	0.0e+00	91.8
QAA28204.1\|1248042_1248273_+	hypothetical protein	A0A2P0ZLG3	Lactobacillus_phage	1.8e-24	88.2
QAA28205.1\|1250650_1250914_+\|holin	holin	E9LUR9	Lactobacillus_phage	2.0e-38	100.0
QAA28206.1\|1250925_1251456_+\|holin	holin	E9LUS0	Lactobacillus_phage	1.1e-40	97.9
QAA28207.1\|1252500_1252926_-	Rcs stress response system protein RcsF	NA	NA	NA	NA
1252164:1252180	attR	NA	NA	NA	NA
QAA28208.1\|1252938_1253058_-	hypothetical protein	NA	NA	NA	NA
QAA28209.1\|1253090_1254161_-	hypothetical protein	NA	NA	NA	NA
QAA30028.1\|1254215_1254731_+	GtrA family protein	NA	NA	NA	NA
QAA28210.1\|1254831_1255191_-	hypothetical protein	NA	NA	NA	NA
QAA28211.1\|1255263_1257120_-	bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase	NA	NA	NA	NA
QAA28212.1\|1257133_1259440_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
QAA28213.1\|1260328_1261966_+	hypothetical protein	NA	NA	NA	NA
QAA28214.1\|1261943_1263119_+	sulfate adenylyltransferase	A0A2P1ELS9	Moumouvirus	3.8e-49	31.7
QAA28215.1\|1263121_1263745_+	adenylyl-sulfate kinase	A0A2K9L4R9	Tupanvirus	4.8e-27	40.6
QAA28216.1\|1263734_1264691_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
QAA28217.1\|1264911_1266651_+	aryl-sulfate sulfotransferase	NA	NA	NA	NA
QAA28218.1\|1267156_1268932_+	SLC13 family permease	NA	NA	NA	NA
QAA28219.1\|1269207_1270599_+	MATE family efflux transporter	NA	NA	NA	NA
QAA28220.1\|1270725_1270971_+	DUF2187 domain-containing protein	NA	NA	NA	NA
QAA28221.1\|1271359_1271806_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
QAA28222.1\|1272077_1273766_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	1.5e-75	32.9

DBSCAN-SWA_4

1299871 : 1309695

Lactobacillus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAA28245.1\|1299871_1301101_+	hypothetical protein	A0A2P0ZL72	Lactobacillus_phage	7.1e-216	97.7
QAA28246.1\|1301177_1302149_-	peptidase S41	A0A2P0ZL68	Lactobacillus_phage	1.0e-180	98.5
QAA28247.1\|1302334_1303282_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.7e-178	100.0
QAA28248.1\|1303242_1303572_-	hypothetical protein	NA	NA	NA	NA
QAA28249.1\|1303624_1304239_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	6.3e-112	100.0
QAA28250.1\|1304241_1306680_+	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	0.0e+00	99.8
QAA28251.1\|1306767_1307328_+	hypothetical protein	A0A2P0ZL75	Lactobacillus_phage	2.7e-101	100.0
QAA28252.1\|1307398_1307839_-	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	4.0e-76	98.6
QAA28253.1\|1307934_1308072_+	hypothetical protein	NA	NA	NA	NA
QAA28254.1\|1308699_1309695_+	glycosyltransferase	S5FKN0	Shigella_phage	3.1e-52	38.8

DBSCAN-SWA_5

2156100 : 2164840

Lactobacillus_phage(33.33%)

tail,terminase,capsid,head,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAA29052.1\|2156100_2156370_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
QAA29053.1\|2156488_2158012_-\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	3.7e-44	25.4
QAA29054.1\|2158008_2159109_-\|portal	phage portal protein	A0A2H4J9Q5	uncultured_Caudovirales_phage	1.6e-49	34.9
QAA29055.1\|2159109_2159310_-	hypothetical protein	NA	NA	NA	NA
QAA29056.1\|2159263_2160967_-\|terminase	terminase large subunit	A0A2H4JBN3	uncultured_Caudovirales_phage	1.1e-121	40.7
QAA29057.1\|2160963_2161437_-\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
QAA29058.1\|2161557_2161800_-	hypothetical protein	NA	NA	NA	NA
QAA29059.1\|2162270_2162660_-	endonuclease	A0A1J0MFT4	Staphylococcus_phage	1.0e-19	45.2
QAA29060.1\|2162652_2162991_-\|tail	phage tail protein	A0A2P0ZLF0	Lactobacillus_phage	1.6e-08	33.7
QAA29061.1\|2163000_2163183_-	DUF2758 domain-containing protein	NA	NA	NA	NA
QAA29062.1\|2163445_2164840_-	virulence protein	A0A1W6JQD6	Staphylococcus_phage	3.3e-68	41.6

DBSCAN-SWA_6

2355368 : 2363882

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
QAA29234.1\|2355368_2355947_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-21	33.9
QAA29235.1\|2355939_2356965_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.7e-59	41.0
QAA29236.1\|2356961_2358416_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-50	34.0
QAA29237.1\|2358400_2360620_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.5e-144	39.3
QAA29238.1\|2360612_2361293_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
QAA29239.1\|2361292_2361547_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
QAA29240.1\|2361548_2362280_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	1.6e-37	37.3
QAA29241.1\|2362282_2363413_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
QAA29242.1\|2363396_2363882_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-16	41.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage