CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
LT960613	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 genome assembly, plasmid: P	0 crisprs	NA	1
LT960611	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 genome assembly, chromosome: A	2 crisprs	RT,cas3,DEDDh,WYL,DinG,cas14j,csx1,cas6f,cas7f,cas5f,csa3	9
LT960612	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 genome assembly, chromosome: B	0 crisprs	RT,WYL,cas14j,csa3,csx1	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

35051 : 72068

Acidithiobacillus_phage(20.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON53482.1\|35051_36374_+\|transposase	transposase	NA	NA	NA	NA
SON53483.1\|36397_36757_-	conserved protein of unknown function	NA	NA	NA	NA
SON53484.1\|37348_37792_-	Lytic transglycosylase PilT	A0A0A8J856	Ralstonia_phage	8.8e-07	37.0
SON53485.1\|37853_38189_-	conserved protein of unknown function	NA	NA	NA	NA
SON53486.1\|38273_38660_-	conserved protein of unknown function	NA	NA	NA	NA
SON53487.1\|38683_39028_-	conserved protein of unknown function	NA	NA	NA	NA
SON53488.1\|39711_41535_-	ParB-like partition protein	A0A0F7L836	uncultured_marine_virus	7.8e-17	33.7
SON53489.1\|42415_42748_+	Toxin HigB-2	NA	NA	NA	NA
SON53490.1\|42734_43049_+	Antitoxin igA-2	NA	NA	NA	NA
SON53491.1\|43464_43956_+	Conserved membrane protein	NA	NA	NA	NA
SON53492.1\|44551_46084_+\|transposase	transposase	K4I413	Acidithiobacillus_phage	2.9e-113	42.8
SON53493.1\|46093_46834_+	conserved protein of unknown function	K4HZD4	Acidithiobacillus_phage	1.2e-48	44.8
SON53494.1\|46978_47446_+	conserved protein of unknown function	NA	NA	NA	NA
SON53495.1\|47532_48066_+	conserved protein of unknown function	NA	NA	NA	NA
SON53496.1\|48205_48274_-	protein of unknown function	NA	NA	NA	NA
SON53497.1\|48329_48923_+\|transposase	transposase	A3F636	Streptococcus_phage	1.3e-10	29.0
SON53498.1\|49110_49515_+	S-adenosylhomocysteine hydrolase	NA	NA	NA	NA
SON53499.1\|49517_50459_+	conserved protein of unknown function	NA	NA	NA	NA
SON53500.1\|50466_53061_+	Type I restriction-modification system N6-methylase	A0A2H4PQP4	Staphylococcus_phage	1.6e-92	41.0
SON53501.1\|53053_54313_+	Type I restriction modification system DNA specificity subunit Hsds	NA	NA	NA	NA
SON53502.1\|54474_57591_+	Type I restriction modification system deoxyribonuclease subunit HsdR	A0A220A398	Liberibacter_phage	1.1e-26	23.8
SON53503.1\|58201_59176_-	putative bacteriophage abortive infection protein	NA	NA	NA	NA
SON53504.1\|59401_59533_+	protein of unknown function	NA	NA	NA	NA
SON53505.1\|59543_59657_-	protein of unknown function	NA	NA	NA	NA
SON53506.1\|59856_60072_+	conserved protein of unknown function	NA	NA	NA	NA
SON53507.1\|60040_62161_+	conserved protein of unknown function	NA	NA	NA	NA
SON53508.1\|62573_62870_-	conserved protein of unknown function	NA	NA	NA	NA
SON53509.1\|62919_63099_-	conserved protein of unknown function	NA	NA	NA	NA
SON53510.1\|63133_63598_-	conserved protein of unknown function	NA	NA	NA	NA
SON53511.1\|63613_64084_-	conserved protein of unknown function	NA	NA	NA	NA
SON53512.1\|64523_64613_+	conserved protein of unknown function	NA	NA	NA	NA
SON53513.1\|64609_64897_-	DinI-like protein MsgA	NA	NA	NA	NA
SON53514.1\|64985_65195_-	conserved protein of unknown function	NA	NA	NA	NA
SON53515.1\|65534_66137_+	conserved protein of unknown function	NA	NA	NA	NA
SON53516.1\|66184_66451_+	protein of unknown function	Q2A0A7	Sodalis_phage	1.7e-05	54.5
SON53517.1\|66268_66850_-\|transposase	transposase	A0A077SL39	Escherichia_phage	2.4e-28	47.3
SON53518.1\|66982_67102_-	protein of unknown function	NA	NA	NA	NA
SON53519.1\|67197_67614_-	putative transcriptional regulator	NA	NA	NA	NA
SON53520.1\|67622_67937_-	conserved hypothetical protein	NA	NA	NA	NA
SON53521.1\|68037_68748_+	putative resolvase of Tn3 transposon family	NA	NA	NA	NA
SON53522.1\|69524_70388_+	putative exported nuclease	NA	NA	NA	NA
SON53523.1\|70574_71312_+\|transposase	transposase	A0A077SL39	Escherichia_phage	3.2e-54	50.0
SON53524.1\|71588_72068_+\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. LT960611

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CRISPR-Cas detection and classification

Crispr_ID: LT960611_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LT960611_1

2023611-2023694

Unclear

Consensus_repeat	Method
CTGCCTATTCGGCAGGTCACTGTTA	CRISPRCasFinder

1 spacers

cas6f,cas7f,cas5f

The CRISPR arrays of LT960611_1

>merge|LT960611|1|2023611-2023694|CRISPRCasFinder
CTGCCTATTCGGCAGGTCACTGTTAGGGTCTAATTTGAACGGTTTGTATCGTTTCCTAGCTGCCTATTCGGCAGGTCACTGTTA

>LT960611|1|1|2023611-2023694|CRISPRCasFinder
CTGCCTATTCGGCAGGTCACTGTTA	GGGTCTAATTTGAACGGTTTGTATCGTTTCCTAG
CTGCCTATTCGGCAGGTCACTGTTA

Protein	Signature genes	Signature genes Name	Protein_function
LT960611.1\|SON49921.1\|2030746_2032501_-\|conserved-protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49920.1\|2029738_2030734_-\|Membrane-protein	unknown	unknown	gnl\|CDD\|235264
LT960611.1\|SON49910.1\|2014367_2021363_-\|conserved-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|274730
LT960611.1\|SON49915.1\|2024435_2025479_-\|conserved-protein-of-unknown-function	cas7f	cd09737_cas7f_CAS-I-F	gnl\|CDD\|187868
LT960611.1\|SON49905.1\|2010834_2011488_-\|conserved-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|380437
LT960611.1\|SON49912.1\|2022623_2022998_+\|conserved-exported-protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49904.1\|2009536_2010631_+\|periplasmic-glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
LT960611.1\|SON49911.1\|2021349_2021730_-\|protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49917.1\|2027575_2028790_-\|conserved-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|377670
LT960611.1\|SON49919.1\|2029110_2029728_-\|protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49909.1\|2013903_2014353_-\|conserved-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|379650
LT960611.1\|SON49916.1\|2025485_2027573_-\|conserved-protein-of-unknown-function	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|187867
LT960611.1\|SON49923.1\|2034282_2035800_-\|Type-I-restriction-enzyme-EcoEI-M-protein	unknown	unknown	gnl\|CDD\|280533
LT960611.1\|SON49918.1\|2028843_2029035_-\|conserved-protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49908.1\|2013031_2013370_+\|conserved-protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49914.1\|2023807_2024419_-\|CRISPR-associated-protein,-Csy4-family	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl\|CDD\|187870
LT960611.1\|SON49922.1\|2032504_2034283_-\|Restriction-modification-system-DNA-specificity-domain-protein	unknown	unknown	gnl\|CDD\|341138
LT960611.1\|SON49913.1\|2022920_2023064_-\|protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON49907.1\|2012523_2012862_+\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
LT960611.1\|SON49906.1\|2011650_2012418_-\|Oxidoreductase,-short-chain-dehydrogenase/reductase-family	unknown	unknown	gnl\|CDD\|212491

Protein	Function_ID	Function_description	E-value
LT960611.1\|SON49920.1\|2029738_2030734_-\|Membrane-protein	gnl\|CDD\|235264	PRK04247, PRK04247, endonuclease NucS.	0.00354762
LT960611.1\|SON49910.1\|2014367_2021363_-\|conserved-protein-of-unknown-function	gnl\|CDD\|274730	TIGR03696, tRNA_nuclease_WapA, RHS repeat-associated core domain. This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.	7.39566e-19
LT960611.1\|SON49915.1\|2024435_2025479_-\|conserved-protein-of-unknown-function	gnl\|CDD\|187868	cd09737, Csy3_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas7 ortholog.	6.10791e-142
LT960611.1\|SON49907.1\|2012523_2012862_+\|putative-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	2.05908e-16
LT960611.1\|SON49904.1\|2009536_2010631_+\|periplasmic-glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
LT960611.1\|SON49917.1\|2027575_2028790_-\|conserved-protein-of-unknown-function	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.07857e-10
LT960611.1\|SON49922.1\|2032504_2034283_-\|Restriction-modification-system-DNA-specificity-domain-protein	gnl\|CDD\|341138	cd17249, RMtype1_S_EcoR124I-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to S.EcoR124I TRD2-CR2, S.Eco540I TRD2-CR2, S.Eco540AI TRD2-CR2, and S.Eco540ANI TRD2-CR2. Escherichia coli (R124) S subunit (S.EcoR124I), E. coli ST540 S subunit (S.Eco540I), E. coli ST540A S subunit (S.Eco540AI), and Escherichia coli ST540AN S subunit (S.Eco540ANI) recognize the sequence 5'... GAANNNNNNRTCG ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoR124I -TRD1 recognizes GAA/TTC, and -TRD2 recognizes CGAY/RTCG. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	2.67459e-77
LT960611.1\|SON49909.1\|2013903_2014353_-\|conserved-protein-of-unknown-function	gnl\|CDD\|379650	pfam14568, SUKH_6, SMI1-KNR4 cell-wall. Members of this family are related to the SMI1/KNR4-like or SUKH superfamily of proteins.	2.55943e-14
LT960611.1\|SON49916.1\|2025485_2027573_-\|conserved-protein-of-unknown-function	gnl\|CDD\|187867	cd09736, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	2.39571e-17
LT960611.1\|SON49923.1\|2034282_2035800_-\|Type-I-restriction-enzyme-EcoEI-M-protein	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	3.03742e-110
LT960611.1\|SON49914.1\|2023807_2024419_-\|CRISPR-associated-protein,-Csy4-family	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	1.02853e-40
LT960611.1\|SON49905.1\|2010834_2011488_-\|conserved-protein-of-unknown-function	gnl\|CDD\|380437	cd20303, cupin_ChrR_1, Marinobacter hydrocarbonoclasticus anti-ECFsigma factor ChrR, and similar proteins; 2 heterologous tandem repeats of cupin domain. This family contains bacterial anti-sigma factor such as ChrR from Marinobacter hydrocarbonoclasticus. Anti-sigma factor ChrR is a member of the ZAS (Zn2+ anti-sigma) subfamily of group IV anti-sigmas. It inhibits transcriptional activity by binding to the ECF sigma factor E (sigmaE), an essential factor to mount a transcriptional response to a singlet oxygen and for viability when carotenoids are limiting. This protein family likely contains two distinct homologous functional domains belonging to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	6.43868e-52
LT960611.1\|SON49906.1\|2011650_2012418_-\|Oxidoreductase,-short-chain-dehydrogenase/reductase-family	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.03892e-62

>LT960611.1|SON49913.1|2022920_2023064_-|protein-of-unknown-function
MTHIVLPNSIWRTFCFCHYEEILASDCDVITVVTMKNRSVSDSTSAV
>LT960611.1|SON49912.1|2022623_2022998_+|conserved-exported-protein-of-unknown-function
MKKIILAIMLIVVAPFSLAQESTGPIQELKICATGDKGIGQWIRLLQFKVDNKWYSTLADAYADPSADADNPLTTSIIMMAFSQNLTIKIRATNKSWAPLHSRCGITNGTVFHGNNGDHITITR
>LT960611.1|SON49911.1|2021349_2021730_-|protein-of-unknown-function
MLRVKTLKSRLISFIRVCMWKCVFFVTAAISIFICSKLFYLELMTLEYRSEYSNLVLAESDGNVSINEYPSPVISLQQLIAVNAEEETNQLNIGLGVMKPENESPEVNLTELRTRLNTLVAINENK
>LT960611.1|SON49910.1|2014367_2021363_-|conserved-protein-of-unknown-function
MRTNNAMEVLRPILNILLKLTAVFIFVVNGPHAIASSPSGDARIVLSGQYQTSGGQANYTLPITVSPGRAAHQPQLGLAYRSNGNSDVLGMGWSLRGVSAITRCGQDLITDHQRGGIRFDAEDRYCLDGQRLIAITGSDGGNLTEYRTKKNGYAKVVSYGRNAGGPEFFKVWTQDGRVREYGHKAEARATLPKSKHAYQWLLNSDTDASGENTIQYQYSDFGTKNGVPLIKSVVYAGGKVTFEYKTRSDVRRFYLGGDQIVKDRLMSTINTFDAAHVKVGTYQLTHKVSSATSRTLLERIQYCTLEGCSSSILFDWQSRPIVEWSGFQSTGLKAPRFYDEDRDGQATAYGVLSENTQTGKYQVKDLQGNTHSNVASFTLKGKLGEPKLALNQCKYNLASSYVNGKGEFTPYCQFSQCTGNSCQYSSNGLNAGDIDGDGITETISGFSIADFNGDGIDDKHRFDVVNGGYAYEISGGLSGALPSAGSLELKSMADVNRDGYLDVIMGPSSGSDHLYVYLFTGNTFTEPTKTKFKVESTDRINFADINGDGYPELVAKNTFYQNLFGEISETVLYEASQEVYSLQDINGDGWVDILSRGSNTANVDRQLSVAHQQDKLTKVTEHGVSYTIRYLPATDSNVYTQGSAIKSFPYQSVTPAVELVYTVEKQPQGYAKTHYQYHYAGALSHLQGGGFLGFATVTETEIAAVTTRTETEFEQEDLTLAGSVKSVRVIKNGKKTSEATYQYHSKTFPGYDADYYQTYANQVQRKSFTLGTQIAQRIETITRNVDRFGNVTKEVRQFTGEQAHAGSYTQTTVNQYLSPGQHQNRTVYQLDRNSTHLLPELAQFKAGFTRYCSENGEVYFKANDLIVLIGMPVTTPILAKRNPNYYRLSTPKVQTLDDRSVVTGHLSTASKAEFDSANLHICGQMSFTNQGGKRELQQLASSVPKLVTESGGQFWTLFAPEIKTVVLKDNSTGLSRTTKTQFDYHNTGFMKQQTVLGSDYESGALASKSTSIAWQYDKWGNTKSETLSGTGFTPRITKYEYDPNGLDLTYQVNAKGHRTGVKYNARGLLFETTSALKNRISTFGYDSFERVTQETLPGKGNTSTTDYKLGDACSYALPQTVSCTIYSPAEGGKKIAHYDYAGREIRQLHQGFNGQWVSTDTHWDISGRKTQVTRPYFIRTQKTPPFVTFSYDVLNREISKSEPDTNGNRSRFTTRYDGLKTETTDAKMQKRDVTINVMGYILRKNEPLGAFQTYRYYPDGKLRSSSDSKSNTTHVRYDSLGFRSDLNDPDMGVWHYQYNALGELTYKRDVNGAETRLTYDSLGRKLTQQEGGQTSRWVYDENGAQGTLSRFTGHGNTTEYAYDANGLTQQVTVSSGQERLATGYSYDGFERLQREIRPNGGANNTGRLEVEYVYNPYGYQSAVRSPRSAADDDYSNDKFIHEIRQLLRLALEKANGYLTRAERYQTQAVDFKQKAQQLRNSTINEHQLDAASVGLLGNEHKFAQWCNTEGDCYLKPMGWVIIGVPTSFPIEAVVKGPIYRLDSRYSHNSGTQRVFSTSLISVTKAEFSAHATTQEHDFVVKTASNGQRSLYSEHDVFVAQPDDKTKQALVYTADDLDQAAKLASQKQKHFAGLADKLISLSEQVAQLSGIYCQDAKNVGGKHVSLTHRWAACDNAPTQFGQADELQLMLTQAELEASVGGQQYIYYWQRRDTDAYNHTLSEVLGNGLVNTYEHNANTGRAARIQTTNSGKQIRSLHYRYDQHNNVKSRFDEELGITDNWQYDALDRVKRNTLALADKTRHGVNNTDLTRAFDYRYDSVGNIEFKTGIGGYTYSKKNAGPHAVTQANGLNYAYDAAGNMQRAWKLGAQTDERTLTWTAFNKPESITRNGKKVEFFYDANHNRYRKKTSDGKETFYFGKSYEKVTDTQTGEVQHQHFIYADGKLIALNTQTRNANNTPKQKQVRYLHYDALNSVDLITDGYANVVERRSYDTWGKQRKVSWRNSNNPAEVLQQAITNRGYTGHEAITEVGLIHMNGRVYDPELGRFTSADPYIQAPFETNSFNRYSYVWNNPLKYTDPTGYKTFSEWASDAWDSVTDFFSGGGSGSYTNNGNSDGSHANYGYTTYKNGNGFAPSRSVDISWGNDLGFIQGWNSDKCVGSTCTDAFVEAFSFTGLGSVVVGSYDAMHDISDTLDLYSNDKISAGAFGTSVATSIGIAIVERKLKLGGEVAESVYDRVTKRARRNGHLAGGKHPKTGIPFDKKGHPDFSSVSKKDVEIEFTGSRRKDVKAANEAGGYKKTPEGHVWHHHQDGTTMQLVPRDIHTKTGHDGGFSGG
>LT960611.1|SON49909.1|2013903_2014353_-|conserved-protein-of-unknown-function
MLDTIDNPGRSISESELKEIALYTELEFPTSYKEFLLKFNGGSPSPDAFPIKGHSEEIGGIQVFFGIDREVESSCLNWNYNEYKSRLPDSYIPIACSDTNDLICLVLSEVKHGKIVFWDAEDERSRNYLGNIYEVADSFDLLLEILFED
>LT960611.1|SON49908.1|2013031_2013370_+|conserved-protein-of-unknown-function
MFIHHVNGIDWLVITAFEELKTMFIEDAGAIPSCFSTTSELSLIDQAKRTYGYLPKLSGVITDTGTFQSQNNEEDLNPQLACLVEGRGRVFIYHGGFVAFVDDEQTFITRMD
>LT960611.1|SON49907.1|2012523_2012862_+|putative-transcriptional-regulator
MKNQENFFSRKSAPERSARMVETIYGCKWSLTVYQLLANGVNRPGEMVRLVEGLSTKVLNECLKRNVEFGILNKQIFNELPPRVEYQVTPFGEKFLLILDQLESLQNEIDEM
>LT960611.1|SON49906.1|2011650_2012418_-|Oxidoreductase,-short-chain-dehydrogenase/reductase-family
MNFTKNGIAVVIGGTSGMGFETAKQLVAQNIHVLVVGNNSTKLDKAVLELQSVGHASGWQANLYDDSSVSRLIDHLESLDEGIGYLVNAAGYFNPKAFIEHQESDYDQYMQLNKATFFITQAVSNLMIKNGGGNVVNVGSMWAKQAIKATPSSAYSMAKAGLHSLTQHMAMELADHNIRVNAVSPAVVKTPIYESFIKPEEVDQALEGFNAFHPIGRVGLPKDIANSISFLLSDSADWVTGAIWDVDGGVIAGRN
>LT960611.1|SON49905.1|2010834_2011488_-|conserved-protein-of-unknown-function
MLNMDFSKRLVIETEPLDWIASPAKGVWRKPLEREDKESGHTTSVVRYDPQSSFSEHPHPQGEEILVLDGIFSDETGDFPAGTYIRNPPGSAHSPSSKGGCTILVKLNQFDARDLTQVRINTLETDWLPGIGGLQVMPLHQFEHEHVALVKWPVGERFQPHRHFGGEEIFVLYGTFKDEHAEYPKHTWIRSPHMSEHFPYVEEETVILVKTGHLPID
>LT960611.1|SON49904.1|2009536_2010631_+|periplasmic-glycerophosphodiester-phosphodiesterase
MKKQLITTAILISVSGQVFANADKLVIAHRGASGYLPEHTLEAYSAAYFMGADYIEQDVVMTKDNQLVVLHDHTLDRTTDVMNRYPNRFRMIDGVKRWFAIDFTLAEIKTLRVTEGFKIPDNSEPNQVQDLSKAGFPDRFPLWKSNFQVATFEEAIELIQGLNHSTKRNVGIYPEIKAPWLHQNEGKDISLAVLNTLKAYGYDSKEDMVYVQCFDPTETKRISEVLMPKMNIDLKVVQLLAETSWNETMVVDKEGNITPYNYDWMFKTGAMTEVAKYADGIGPWKPMLVDDQSTPDNIIIKPLMTEAKAAGLEVHPYTFRADKGRIPVYAENFDDMLDVFYFKVGVDGVFTDFTDKAVHFLNSK
>LT960611.1|SON49914.1|2023807_2024419_-|CRISPR-associated-protein,-Csy4-family
MPKRYFFTIRYIPERADCGLLAGRCIEQMHGFAANNPQAKSSIGVSFPSWCSESVGHSIAFVAANKDLLVGLSFQPYFSLMVNEGLFEVSTVDEVPNELPELRFVRNQAIGKSFVGSKKRRIKRSLVRSETIDEKHLPKANEIREFEHFHKVPISSGSSGQDFILHLQREQTVESVATGFNCYGFATNKDWRGTVPDFRFNPN
>LT960611.1|SON49915.1|2024435_2025479_-|conserved-protein-of-unknown-function
MELCSQLNYVRSLSSGKACFYHLGNSDEICPLSIDRTRLRAPKGGYAEGYKGSKFQPKNVAPQDLAYANPQFIEECYVTPGVDEIYCAFSLRIRANSLGPDVCCDDNVREQLTHLAHIYKELNGYRELAQRYAKNILLGTWLWRNRECRGITVEVTTSDSHTITVENAERLSWYGHWGKEATESLESLTVYLAKALSDKSEYFYMDVKAKIGVGWGDEVYPSQEFLDSRQEGLPTKQLATVELSSGQETAAFHAQKIGAALQSIDDWWHQEADKPLRVNEYGADREYVIARRHTKSGNDFYQLLRNTEKWIETMEQSQTIPNDVHFIMSVLIKGGLFNCSKFKSESK
>LT960611.1|SON49916.1|2025485_2027573_-|conserved-protein-of-unknown-function
MKKLSDLLAIEDSIVKQATLKKVFMPYSENVDIDGCEKEALTILVNLSSHHKGDKCADWLDEERAKRHLKNTENIEDSLAEIKWLHTHNLKFPDCRVKDQRVIAKPLPTSESFISSAVSEYSLGWAHNAADYRHTQWILNSFNWQSKPANVLFLAQQGNPVWLELLQDLGLNVKDLVLFQKTIQSQLPVSTLPEYVNSYSKQLRFPWGNDYLSVTPVVSHAIQRELECRRRDPNSSLNFVTMSLPNSASIGNLCGSVGGYMKVLNYPIGARLNSEKTLSVSRQKSGRYFDDYQVTNSKICKVLSHLIGAEPLKTHKQRTKARKDQAKILRRQIALWILPLIELRDLAESEPKKPLIEHSEQLVQNFLTLPESELQSLATLFNQRLHFAFQENEFARKFAYHPKLMQVAKAQVKWVLDKLSQPHNTTTPVHEEQYIYLSSLRIQDAVAMSSPYLCGAPSLTAIWGVMHHYQREFNQLIDGSANFEFSSFALYVRSEAIRNTAKLTEPNSLAKARTISNAMRPTIRREMLTDLEIDLVIKVKSNDRISDYATALKASLPFTFAGGTLFQPLISSNKKWLRTFNGCTDLFYSLKGLPAYGSWLYACDKQPKDLDELEASLERNHDVLPISLGFHFLEQPKTRKNALTGSHAYVENALGIAERVNPIEVRFAGRDHFFNHAFWSLECSGETILIKKDRN
>LT960611.1|SON49917.1|2027575_2028790_-|conserved-protein-of-unknown-function
MNTDIQLYADESLESFLLRLSQEQGYERFSHFAEDIWHDTMEQHEAIPGAFPLELNLVNIYHAQTTSQMRARVFIYLEKQLKLNNFGVLKLSLAHSKSKFSPEFKALNRFGTDYPYALIRKRFTPICPQCLEDAPYIRQQWQFISYQACHLHGCKLLHRCPECSSLLEYQMTESATQCECGFDLIGCKSGKAPEPEYMVALWLSGGKTEASSGVMAQEMTVSERYGFMLWYVNRYGDLDDINLESFVQSCVSWPNILKEDLDERVKKAEQVRVKDWKQMFFSEVFGSLLKGCRQLPSRQLSKNIVLTEVLAYLTRLVADSPATAKGNIGDVLLSPLEASSLLSCVTDEVYRLYEFGEIKAAIRPRMHIKIASHESAFTLRSVIETKLTRMCSESDGLSVYLPEW
>LT960611.1|SON49918.1|2028843_2029035_-|conserved-protein-of-unknown-function
MVLGVWMAMIIAKPPTNSNALNLDVGLFMERMGPMYFKESALNAKVASEASVSSHNLLLIDLI
>LT960611.1|SON49919.1|2029110_2029728_-|protein-of-unknown-function
MNELKGLLADLDDKKITLSVRGLFYDQINLKVNGCYVFTHSKTSDKFEAQIGFLSKLHEDGRLYNPKVSKTAKIHVKQTITDNRKLPAKKVQNFGKSLESYAKLSLTKSRPESDEVREMEELIAEMRPLNFRTSKQLSKYIVDNNLGGKYPTISGVARMKNASDEWDFKGGFPPDIYKMICIRLGLRNQGTSTRLIGFSSYKSLI
>LT960611.1|SON49920.1|2029738_2030734_-|Membrane-protein
MSLYNIANKNLTALRPTTFAAEGLQERQDLQEALKGCIDAIAPDCLVISEEFSDWEDSRRRIDLLAIDRNANLVVIELKRDDVGAHMELQALRYAAMISTMTFEKACDYFEQYIEKEGLDIVARQEILDFVDLDEGSLDDFGNDVRIVLASADFGKELTTSVLWLRDKGIDISCVRLAPYRYKDDVLINAEQIIPVPEVEEYQVKFREKRQEQRVSSNYVDKDYSEYQYKGAVYNKRHLSYALLSDWIEKHNPQDLDKLQAAFNGVLRKSVFTLVSEIHEKRRKRFHMKEGQTIELESGEIIAISNQWGVGNIYNLIERVELDGFEVIQSN
>LT960611.1|SON49921.1|2030746_2032501_-|conserved-protein-of-unknown-function
MILATFLKNMLWDDEASGDARRFARLKPIKNEETFYSVSIDDDLFSRLIWPMNTFHVLAKIFDTYDVYQKIVSLENETDYLSQFHSGHGRNWGESLIKAETSQEIFISSRFYSLLYSLFSRSRVSMKIEDLLEDSGYLRALFQLYIASDACAYRIQSYLYRNSPPLINEYSEKLVARKGRSIISSLSQCDKTNGVIQFKSHTPQAGISLNSLSHDLAYIKPGVEVAALVGNSTQSRESHQYNVLILPWPLEVKDEFFEQDDKPTLQMDEGFGFFAYVNHHAITCQMVIYAIESCEEQSPDLVVIPECAVNSNDKRNLLEGLRAHFLAKGTTPPVIIFGIFGEGDCRGTYGENSLDLLYENRFVDRYVGENQKKHHRWALDETQLNTYGLGHVLSTDKVKWWENCSTGERKLISYQDDYIHICPLICEDLARQDPIAPVLRSLGPDLVVALLLDGPQIPQRWPGTYAKMLTEEPGCSVLSISPYGMTQRSTGDINPATGLNYEPSSNIALWSEVGGAQQTLELEKGRVGILLTLKFSEQKQWSADGRGENKRRLFYFNHHSVGDTVELSNLELPKVQGKKLTESA
>LT960611.1|SON49922.1|2032504_2034283_-|Restriction-modification-system-DNA-specificity-domain-protein
MSAEQTSMNQLITDNIDVWTSTVKTKSASGRGSSKKRELYGVKKLRELILELAVRGKLVPQEPTDEPASVLLERIAEEKEQLVKDKTISRTKALPALLDEDIPNDLPKGWSMVRLGNLTSKLGSGSTPRGGKNVYTTEGIPFLRSQNVRNEGIKLDDIAYIPVEVHQKMDKTKVIPSDVLLNITGASLGRSTVFPESLVEANVSQHVTIIRLIERQMSQFVHLGILSPMVQKLVWGRQVGMAIEGLSKKVLEMFEFPVPPLEEQHRIIAKVDELMTLCDQLEQQTEASIEAHQVLVTTLLDTLTNSADAEELMQNWARISEHFDTLFTTEASIDQLKQTILQLAVMGKLVPQDPNDEPAAKLLERIAEEKAQLIKEKKIKKQKALPQIADDEKPFELPKGWEWCRFGELGYDLGGGTPSKGNSEYWGGSIPWVSPKDMKRDYIESAIDSVTEKAVLETTIKLIPENSLLMVVRGMILAHSFPVALTKKPVVINQDMKALIYNYIEPEFLLVVMKGIKNEMVDLVDRSSHGTCKLVSDKLWSVVLAVPPLSQQRQIVKKANELLGICEQLKGSLKESQTTQLHLTDAIVEQAV
>LT960611.1|SON49923.1|2034282_2035800_-|Type-I-restriction-enzyme-EcoEI-M-protein
MSISSAIKSIQDIMRKDAGVDGDAQRLGQMSWLLFLKVFDAQEEELELELDDYKSPIPEQYLWRNWAQDAEGITGEALLEFVNDDLFYKLKNLTAPVDLNPRGFVVKEAFSDAFNYMKNGTLLRQVINKLNEIDFTDSSERHLFGDIYEQILKDLQSAGNAGEFYTPRAVTRFIVNRLDPKLGEAIMDPATGTGGFLACSFDHVKDNYVKTAADHQTLQKQIHGVEKKQLPHLLCITNMMLHGIEVPVQIKHGNTLNKPLSSWDSNINVIATNPPFGGTEEDGIEKNFPAEMQTRETADLFLQLIIEVLDEGSETQSGGRAGVVLPDGTLFGEGVKTKIKKMLTEECNLHTIVRLPNGVFNPYTGIKTNILFFTKGKPTKDVWFYEHPYPEGVKNYSKTKPMKFEEFQQEIDWWGNEEDGFASRVENNHAWKVPIADIIERNFNLDIKNPYQGEVISHDPNELLENYQQQQQEISQLRNQLKDILGDALKSSVDSTSVTATGESK

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Crispr_ID: LT960611_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LT960611_2

3352537-3352683

Orphan

Consensus_repeat	Method
AAAAAAGCCTCATCTAATGATGAGGCCTTTTTAATAGTGGTCGGTGAAGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LT960611_2

>merge|LT960611|2|3352537-3352683|CRISPRCasFinder
AAAAAAGCCTCATCTAATGATGAGGCCTTTTTAATAGTGGTCGGTGAAGAGCCGACTTTGAATAAGCCGAACCCCCGACTCTCGGGTTTTAAACGTAAAAAAGCCTCATCTAATGATGAGGCTTTTTTAATAGTGGTCGGTGAAGAG

>LT960611|2|2|3352537-3352683|CRISPRCasFinder
AAAAAAGCCTCATCTAATGATGAGGCCTTTTTAATAGTGGTCGGTGAAGAG	CCGACTTTGAATAAGCCGAACCCCCGACTCTCGGGTTTTAAACGT
AAAAAAGCCTCATCTAATGATGAGGCTTTTTTAATAGTGGTCGGTGAAGAG

Protein	Signature genes	Signature genes Name	Protein_function
LT960611.1\|SON51156.1\|3346353_3347298_-\|dipeptide-transporter;-membrane-component-of-ABC-superfamily	unknown	unknown	gnl\|CDD\|224094
LT960611.1\|SON51154.1\|3344646_3345231_+\|putative-Phosphatidic-acid-phosphatase-type-2/haloperoxidase	unknown	unknown	gnl\|CDD\|239488
LT960611.1\|SON51169.1\|3363341_3364106_+\|Binding-protein-dependent-transporters-inner-membrane-component	unknown	unknown	gnl\|CDD\|223673
LT960611.1\|SON51170.1\|3364083_3364773_+\|Taurine-transporting-AtPase	unknown	unknown	gnl\|CDD\|224041
LT960611.1\|SON51163.1\|3353602_3354007_+\|Cytochrome-c5	unknown	unknown	gnl\|CDD\|225784
LT960611.1\|SON51158.1\|3348427_3348889_-\|Peptide-ABC-transporter,-periplasmic-peptide-binding-protein-(fragment)	unknown	unknown	gnl\|CDD\|173863
LT960611.1\|SON51168.1\|3361912_3363196_+\|conserved-protein-of-unknown-function	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
LT960611.1\|SON51152.1\|3342393_3343371_+\|conserved-membrane-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|307170
LT960611.1\|SON51164.1\|3354096_3356193_-\|DNA-helicase-and-single-stranded-DNA-dependent-ATPase	unknown	unknown	gnl\|CDD\|130146
LT960611.1\|SON51157.1\|3347300_3348278_-\|Peptide-ABC-transporter,-permease-protein	unknown	unknown	gnl\|CDD\|223674
LT960611.1\|SON51155.1\|3345270_3346245_-\|conserved-exported-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|335993
LT960611.1\|SON51160.1\|3350088_3351804_-\|Glutathione-import-ATP-binding-protein-GsiA	unknown	unknown	gnl\|CDD\|224048
LT960611.1\|SON51159.1\|3348885_3349980_-\|Peptide-ABC-transporter,-periplasmic-peptide-binding-protein-(fragment)	unknown	unknown	gnl\|CDD\|173863
LT960611.1\|SON51166.1\|3356908_3357994_+\|conserved-protein-of-unknown-function	unknown	unknown	gnl\|CDD\|273776
LT960611.1\|SON51153.1\|3343432_3344584_+\|Amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|349916
LT960611.1\|SON51151.1\|3341162_3342329_+\|Peptidase-M24	unknown	unknown	gnl\|CDD\|223085
LT960611.1\|SON51167.1\|3358005_3361122_+\|Uncharacterized-transporter-HI_0895	unknown	unknown	gnl\|CDD\|169983
LT960611.1\|SON51171.1\|3364822_3365779_+\|Aliphatic-sulfonates-family-ABC-transporter-periplasmic-ligand-binding-protein	unknown	unknown	gnl\|CDD\|130789
LT960611.1\|SON51162.1\|3352718_3352871_+\|protein-of-unknown-function	unknown	unknown	unknown
LT960611.1\|SON51165.1\|3356287_3356869_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
LT960611.1\|SON51156.1\|3346353_3347298_-\|dipeptide-transporter;-membrane-component-of-ABC-superfamily	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.45149e-100
LT960611.1\|SON51154.1\|3344646_3345231_+\|putative-Phosphatidic-acid-phosphatase-type-2/haloperoxidase	gnl\|CDD\|239488	cd03394, PAP2_like_5, PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	3.57972e-32
LT960611.1\|SON51169.1\|3363341_3364106_+\|Binding-protein-dependent-transporters-inner-membrane-component	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	5.62036e-68
LT960611.1\|SON51163.1\|3353602_3354007_+\|Cytochrome-c5	gnl\|CDD\|225784	COG3245, CycB, Cytochrome c5 [Energy production and conversion].	4.36339e-41
LT960611.1\|SON51158.1\|3348427_3348889_-\|Peptide-ABC-transporter,-periplasmic-peptide-binding-protein-(fragment)	gnl\|CDD\|173863	cd08498, PBP2_NikA_DppA_OppA_like_2, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	6.27583e-57
LT960611.1\|SON51168.1\|3361912_3363196_+\|conserved-protein-of-unknown-function	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.53445e-166
LT960611.1\|SON51152.1\|3342393_3343371_+\|conserved-membrane-protein-of-unknown-function	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	8.5626e-12
LT960611.1\|SON51164.1\|3354096_3356193_-\|DNA-helicase-and-single-stranded-DNA-dependent-ATPase	gnl\|CDD\|130146	TIGR01074, ATP-dependent_DNA_helicase_Rep, ATP-dependent DNA helicase Rep. Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
LT960611.1\|SON51157.1\|3347300_3348278_-\|Peptide-ABC-transporter,-permease-protein	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.38942e-107
LT960611.1\|SON51155.1\|3345270_3346245_-\|conserved-exported-protein-of-unknown-function	gnl\|CDD\|335993	pfam05036, SPOR, Sporulation related domain. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.	0.000289568
LT960611.1\|SON51160.1\|3350088_3351804_-\|Glutathione-import-ATP-binding-protein-GsiA	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
LT960611.1\|SON51159.1\|3348885_3349980_-\|Peptide-ABC-transporter,-periplasmic-peptide-binding-protein-(fragment)	gnl\|CDD\|173863	cd08498, PBP2_NikA_DppA_OppA_like_2, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	6.30704e-156
LT960611.1\|SON51170.1\|3364083_3364773_+\|Taurine-transporting-AtPase	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.13441e-82
LT960611.1\|SON51153.1\|3343432_3344584_+\|Amidohydrolase-family-protein	gnl\|CDD\|349916	cd05666, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0
LT960611.1\|SON51151.1\|3341162_3342329_+\|Peptidase-M24	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	3.30565e-78
LT960611.1\|SON51167.1\|3358005_3361122_+\|Uncharacterized-transporter-HI_0895	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
LT960611.1\|SON51171.1\|3364822_3365779_+\|Aliphatic-sulfonates-family-ABC-transporter-periplasmic-ligand-binding-protein	gnl\|CDD\|130789	TIGR01728, Putative_aliphatic_sulfonates-binding_protein, ABC transporter, substrate-binding protein, aliphatic sulfonates family. Members of this family are substrate-binding periplasmic proteins of ABC transporters. This subfamily includes SsuA, a member of a transporter operon needed to obtain sulfur from aliphatic sulfonates. Related proteins outside the scope of this model include taurine (NH2-CH2-CH2-S03H) binding proteins, the probable sulfate ester binding protein AtsR, and the probable aromatic sulfonate binding protein AsfC. All these families make sulfur available when Cys and sulfate levels are low. Please note that phylogenetic analysis by neighbor-joining suggests that a number of sequences belonging to this family have been excluded because of scoring lower than taurine-binding proteins. [Transport and binding proteins, Other].	3.13277e-32
LT960611.1\|SON51166.1\|3356908_3357994_+\|conserved-protein-of-unknown-function	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.74446e-74
LT960611.1\|SON51165.1\|3356287_3356869_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.94188e-18

>LT960611.1|SON51160.1|3350088_3351804_-|Glutathione-import-ATP-binding-protein-GsiA
MSLLEVRDLRIEYPSRHGVHAAVKSLSFNIERGEIVGVVGESGAGKSTVGNAVIDLLSPPGLVANGDVFLDGEKISGLTPEQMRSVRGSKIGFIFQDPMTSLNPLFTVEHQLKETIHANMKVSDKEAYERSLSLMNQVGIPQPENRLKQYPHQFSGGMRQRVVIAIALAGEPDLIIADEPTTALDVSIQDQILTLIRDLCIEKNVGCMLVTHDMGVVSNVTDRVAVMYRGDLVEIGPTKKVLGDPDHSYTRSLISAVPRSDVKLGRFPLVSYIEEAEELQQLDVKNHWLGQSQDQREYEGPLLDVQNVNLRFITKDSLFESRREYVQASHNVSFEVHEGETFGLVGESGSGKSTIARIIAGLYTPDSGTVSFESVDLTSLKSEKERRPMRRQMQMVFQNPYTSMNPRMKIFDIIAEPIRFHKLTANEAETRTIVNDLLDHVGLGVMAGLKYPHEFSGGQRQRISIARALATRPRLLICDEPTSALDVSVQAQILNLLKDLQDELNLTMLFISHDLPVIRQMCDRIGVMQMGTLLEVAPTEQLFTDPQHEYSKQLISLMPEFTGLREDVQTA
>LT960611.1|SON51159.1|3348885_3349980_-|Peptide-ABC-transporter,-periplasmic-peptide-binding-protein-(fragment)
MKTMKSKLAVALMAAGLSFGAAAADITVGYAADPVSLDPHEQLSGGTLQMSHMVFDPLVRFTQTMDFEPRLAESWERVDNETMRFTLRKGVKFHSGNAFTADDVVWTFSRLKSSPDFKGIFGPLVSLTKVDDYTVEVKTDGTYPLIENVATYIFPMDSKFYSGKTAAGEDKAALVKHGNSYASTNVSGTGPFTIKSREQGVKVEFERFGNYWDTASKGNVDNLTLVPIKEDATRVAALLSGDVDMIAPVAPNDYKRIKKAKSVDLYTMPGTRIITFQMNQNSNEALKDVRVRQAIVYAVNNEGITKKIMKGAATAAAQQSPVGYAGYNEDLKPRYDLKKAKALMKEAGYADGFTLSMMAPNNRL
>LT960611.1|SON51158.1|3348427_3348889_-|Peptide-ABC-transporter,-periplasmic-peptide-binding-protein-(fragment)
MNDAKIAQATSAMLSKIGIKVDLKTMPKAQYWPEFDKCAADMMMIGWHPDTEDSANFSEFLTMTRDEATGKGQYNCGGYSNPELDKLVIGTNAETDLKKRSATLKQVEATLYNEAAFVPLHWQDPSWAAKSNVEIGPIINGMNFPYFGDLVVK
>LT960611.1|SON51157.1|3347300_3348278_-|Peptide-ABC-transporter,-permease-protein
MFTFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSESERQALRDDLGLNDPFITKYSRFIGKAVQGDLGTSYFFKRPAVDVILDKLVATLELVFGAAVIIVVCSIPLGVYSAIHPKSIFTKIVMAGSSIGISVPVFLTAILLMYVFSIELGWLPSYGRGDTANWFGWESGYLTADGLAHLVLPCIALASIMLPLFIRLVRSEMLEVLSSEYIKFGKAKGLALNKIYYQHALKNTMLPVLTVGGVQIGTMVAYTILTETVFQWPGTGFLFLEAINRVDTPLITAYVIFVGLLFVVTNTIVDLLYGIINPTVNLTGKGA
>LT960611.1|SON51156.1|3346353_3347298_-|dipeptide-transporter;-membrane-component-of-ABC-superfamily
MTTSTTSSVPSRFERFKQSDFLYYFLKDKVAMFSFAVFMVFLVMALAAPIIAPTDPYDLMSIDLMDSELPPSWMEGGDERFLLGTDEQGRDILSTMLYGSRLSLTIGFLAVGLQLFLGIIIGLSAGYFGGRIDSFLMRFADVQLSFSTMMVAIIVSAIFKASFGSDFYAQYAVVMLVVIIGVAEWPQYARTIRASVLAEKKKEYVEAARVMGFKSPRIMFRHILPNCLSPILVISTVQVANAIMSEAALSFLGLGLPVDQPSLGALISIGFNYIFSGAWWITAFPGVLLVTLVLVINLLGDWLRDVFNPKIYKG
>LT960611.1|SON51155.1|3345270_3346245_-|conserved-exported-protein-of-unknown-function
MDGKLTAKVALPVLALLCALALPTGKAMADEEYLCDAVQVSKNELPMLKGNCPIGNGVWGKKKPQNAQGLFWIQCGILTKPMSLTGAKRIYQKISTDVWMKQEGREYRCLIGPYEDFATANQEKIKVRQLTAYKDAFVREVVEKGKTEPAKPQTSASSKPMPKAALVAAPVTPQKVTAKKPDAVAANKPVKNKPIASKQAEPEKLAKPAKMVSGDIEIRRQSKLGIHTYVVPYVLEDNNSFYMEYDRAWNRMNYQSAQALCHKLDMRLAKNEEWQAILDSGELVKNKWPIHLPYWGDSNQGFFTNGKVTQLKGSSLLNVLCIEP
>LT960611.1|SON51154.1|3344646_3345231_+|putative-Phosphatidic-acid-phosphatase-type-2/haloperoxidase
MLSATMPRLLNINQGMIVPMNKSLPLLCLSAAMLASNAHAQSALTTYGDIAQIGIPLTAGAISLYKGDKEGFVQLAEGALYTVIATQGLKYAVNAERPNGGEHSFPSGHTSAATQGAAYLQFRYGAAYGVPAYAAAALVGYSRVEGEYHHWRDVIAGMALATGIQYAVTEAGYSITVHPYFADKETGIFAQMNF
>LT960611.1|SON51153.1|3343432_3344584_+|Amidohydrolase-family-protein
MTLEQTVIEWRRHLHQFPEFGTEEFKTAEFVANKLNEFGLEVHTGIGGTGVVGILKNGTSERTIGLRADMDALRIQEANTFCHASKHEGAMHACGHDGHTAMLLGAARELAQNKNFDGTVYFIFQPDEERGTGAKAMIADGLFTRWNMDAIYAMHNLPGIPEGQFVTRPASLMASESSFEIVINATGGHAAMPHMGTDPIVVGAQIVTALQTIVSRNLSAIDETAVLSVTNFVTNGTVNVIPSQVTITGDTRSFTDQALHKIEAAIERVVAGQCMSAGVDYQYNFNNSFLSIINSPNETTHAVRAAQATVGADRVNGNCERFTISEDFSFMLREVKGCYVLVGNGVGECGGTALHNPYYDFNDNIIKDGVAFWNTLVQQQLPA
>LT960611.1|SON51152.1|3342393_3343371_+|conserved-membrane-protein-of-unknown-function
MNTTNRDTILGWTAAIAVAFIWGVTGVVSKPLSMAVDPMTLVFFRYVTAVIGLSIIYFFTSRNKSLSEDLGSSLKIDTKDIGRIALCGIVGQGVFSLFNFLSLSHIGATENGVIQGMQPFATVFFGMMFMNFRMNKIQWGAFIASAVCIYAMSVGPTNTIEGGTPLLGYVYVTCSMLALAWTAHLRASLADKYGSVVSMLYQYISVAVMGIIVVTTMGLDLSQIYIIFSSPLLIGLLIFLGTGISGGSYLVQLYAFKRIGVEKATMALNLMPLVGYIVAVLTLGEQMALGKTVIVSLIVVALYVFTKYETRTAPKDEQKLETQKA
>LT960611.1|SON51151.1|3341162_3342329_+|Peptidase-M24
MTDYLNRGFAQAEFENRTSRAQKIMHEQKLDAMIFTTEPNVRYFTGFHTQFWHSPTRPWFVIVPAEGKPIAIIPEIGASGMASTWVDNTITWPSPRPEDDGISLVASALNSLPCRHGRVGATLGIESHLRMPVNNYLKLTTMVKKDFVDVSLAMHELRQIKSQAEIEKTREICRITNIGFNKIPDYAKAGMTEREICKQFRIDMLLEGADECPYIIAGSGPDGYDSIIMGPTDRIIESGDVLIIDTGAVRDGYFSDFDRNWAFGHASEQTKAAYRATYEATTKGFEAAKPGATTTDIYNAMWGVLEANGALGNDVGRLGHGLGMELTERPSNTATDNTVLKPGMVMTLEPGMVYAPGKSMVHEENIVITEDGAEWLSERAEPELIVIK
>LT960611.1|SON51162.1|3352718_3352871_+|protein-of-unknown-function
MRYQAALFTDIGFILINQKRKLMGLVTELMGWLTRFELATTGITIQGSTN
>LT960611.1|SON51163.1|3353602_3354007_+|Cytochrome-c5
MDMSRPILSLLAATLVFSSSAFAASVDRDAIEKRIQPVGQVYLAGSEPVAAEPAGPRDGATVYNTFCTACHTSGVSGAPIKGDAGQWGSRIAQGRDVLNNHALNGFNAMPAKGSCMDCSDDEIIAAIDYMIEGL
>LT960611.1|SON51164.1|3354096_3356193_-|DNA-helicase-and-single-stranded-DNA-dependent-ATPase
MQWIGHSFQTLARLLYSPNNENLLECKMKLNPRQDEAVKFVSGPCLVLAGAGSGKTRVITNKIAYLVQQCGYKARNIAAVTFTNKASREMKERVGQTLGKQESKGLMVSTFHTLGLNIIRKEYKALGLKAGFSLFDDQDQLALLKELTETQLDGDKDLLKALMSSISNWKNDMLTAEQVKGQAKGEQDQLFAFCYEMYLKQMKAYNALDFDDLISLPVLLLRTNEEVRKRWQSRIRYLLVDEYQDTNTSQYELVKLIVGERGRLTVVGDDDQSIYSWRGAKPQNLVLLGKDYPNLRLIKLEQNYRSTSRILRSANILIANNPHVYEKRLFSEIPDGEQLKVLHVKNEEHEAEKVTGEIIAHKFLNRTDYKDYSILYRGNHQSRLIEKALMQNRIPYKISGGTSFFSRAEIKDIMAYLRVLVNPDDDNAFLRIVNTPRREIGPVTLEKLGSYANMRGKSLFEASFEMGLEQTLTGRGLENLQRFTRWIVAISDNAERGNTVEAVRSLVRDIHYEDWLYETSASPKAAEMRMKNVSDLYSWIVADLEGDNYDKEIKTLKEVVLRLTLRDMMERGEDDDDADQVQLMTLHASKGLEFPYVYLIGAEEGILPHQTSIDEENVEEERRLMYVGITRAQKELTFTICKERRQYGELIKPQQSRFLDELPQDDVEWESTKKPQSAEERMEKGQAHIANIRAMFKK
>LT960611.1|SON51165.1|3356287_3356869_+|TetR-family-transcriptional-regulator
MSISTEQDKREKILNATEAVLAEEGFQGISMQKIAKNAGVAAGTIYRYFEDKDHLLKEIRFRVTKRIADHLQANVSETMPIKERYQVMWLNLWNLARDNCFLLSNRVQYDSLPKPSSSEEWQQEREMFHKVELTFNEGKESGLFKPLDNRILFGLSLEVGVTLARKHSLGIIHIDDETLDAAIAASWDAIIQH
>LT960611.1|SON51166.1|3356908_3357994_+|conserved-protein-of-unknown-function
MLLIAILLFGSVIGFNLFKQQKIAEYLANRPEPEFPVTAQEVVSIDWVPNIEAIGFIEPNQGVTLTTETSGVINRIDFESGSAVKKGQVLVALDSTVERANLKSTQARLPAAEAKFKRYEGLYKKGSVSKESFDEAKAAYFSLEAEIESSKASIARRTLKAPFDGVVGIRNVYLGQYLQPSTEIVRLEDTNVMRLRFTVPQTDIPRIHIDQKIKISVDAYPEDSFEGTISAIEPAVSVQSGLVQVQADIPNNDGQLRSGMFARANIILPAITEQVTLPQTAITFTLYGDSVYIISEEDGQQRVKQHVIKVGERKADIAHVLEGVEPGDLVVTSGQVRLSNDAKVRIVENDATTPPAETPML
>LT960611.1|SON51167.1|3358005_3361122_+|Uncharacterized-transporter-HI_0895
MRFTDVFIKRPVLAVSISFLIALLGFQAIFKMQVRQYPEMTNTVVTVSTSYYGASADLIQGFITQPLEQAVAQADNIDFMTSQSVLGKSTITVTMKLNTDPNAALADILAKTNSVRSQLPKESEDPTVTMSTGDSTAVLYIGFTSDELSSSQITDYLERVINPQLFSVNGVSKIDMYGGMKYALRVWLDPAKMAALKMTATDVMQVLNANNFQSATGQATGEFVLYNGSADTQISNVAELEKLVIKSDVGEVIRLGNIAKVTLEKSHDVYRASANGQEAVVAAINGAPSANPITIAKDVLELLPQLRKNLPSNISMEVMYDSTEAINESINEVIKTIVEAALIVLVVITLFLGSFRAVMIPLVTIPLSLIGVAMVMQAMGFSWNLMTLLAMVLAIGLVVDDAIVVLENVDRHIKLGESPFRAAVIGTREIAVPVIAMTLTLGAVYAPIALMGGITGSLFKEFALTLAGAVFVSGIVALTLSPMMCSKMLKANETPNRFETTVHGFLDRMSNGYEKMLGNVMQRRPVIIAFAIIVFASLPMLFKFIPSELAPAEDKGVVMLMGTGPSNANLDYLQNTMNQVNEILTEQPEVKFAQVFTGVPASNQAFGLASMVPWSQREASQAEVSKRIGELVQDVPGMAVTAFQMPELPGAGSGLPLQFVITTPNSFESLFQIATDILADVSVNPLFVYSTLDLNYDSATMKIHIDKDKAGIYGVTMQDIGMTLSTMMADGYVNRIDLNGRSYEVIPQVERKYRLNPESMNNYYVRAADGNAIPLGSLIDIEVVAEPRALPHFNQLNSASIGAVPSPGVAMGDAVNWFENVAQSKLPSGYNHDYMGEARQYVTEGSALFATFGLALAIIFLVLAIQFESVRDPLVIMVSVPLAICGALISLAWGAASMNIYSQVGLITLVGLITKHGILICEVAKEEQLHNKKDRIAAVTEAAKVRLRPILMTTAAMIAGLIPLMYATGAGAAQRFSIGIVIVSGLAIGTIFTLFVLPVIYSYLAEKHKPLPVFLEDKDLEKLARVDEAKAAQREIRE
>LT960611.1|SON51168.1|3361912_3363196_+|conserved-protein-of-unknown-function
MRVYYSLYGHLLHKERLYKGFKKVWKAKGAAGIDRQSLSDYAQNLSDNLDQLLLELKTKRYTPQPVRRVEIPKDDGGVRLLGIPTVRDRVVQQALNDLLTPIFEEQFHPSSFGYRPNRSCHDAINKATMFIRRYGMQHVVDMDLSKCFDKLDHELILKSIKKRVTDSSVLELIKQFLKSGVMVDGEWQHTEIGSPQGGVISPLIANIYLDAFDQEMRKRGHRIVRYADDILIFCRSRKGAENAQVQATKVLEKQLKLTVNETKSHIAHSGEGVKFLGIEIGSHYSRIQPKKMSTFKGKLKRVTRRNGGKPLLEVIKQLNPLLRGFSQYFRIANANREFKKLAAWLRRRLRSVQLRLWKKPTRLHRRLRQLGYEGSFRYICMDSWRNAASPLASYSMPNQWFNDLGLVNLEHVRTGYVFSHYAEWKCA
>LT960611.1|SON51169.1|3363341_3364106_+|Binding-protein-dependent-transporters-inner-membrane-component
MQAPTNRINTAIKALLLPVILFVGWHLCCQHLSLSNYLLPTPSMVFGALFDMIISGELFSHVVASLTRVMIGFVLTSSVALSFACIFIRFPQCYAYFHVTFEAIRVIPPLAFSPLLIVWMGIGEGPKITIIFLAAFFPIFLNAYSGLRNIDTRYLELAKSLDLSRFETIKHIHFPFAVPSIVTGLRLGFGYSWRALMGAELIAAASGLGFLIVDAEELARTDKAMAGIIVIAILGLILDTLIKRLTKNAHYCSA
>LT960611.1|SON51170.1|3364083_3364773_+|Taurine-transporting-AtPase
MLTIARLNKFFLNQQGQAESILHDINFELSQGEFVAIVGHSGSGKTTLLKCLAGLESCQSESFEYHHPITTAVVFQEPRLLPHYSVEKNLRLAFAANRRNDQATDQCIHQQLSLVGLSDYADNFPSELSGGMAQRAAIARALCRKPDVLFMDEPFSALDIITRQTMQKELKTIHKTAQCSVIFITHDIQEAITLADRIVVMNKGRITEEFSGDTLSNAEQRIVEATRTN
>LT960611.1|SON51171.1|3364822_3365779_+|Aliphatic-sulfonates-family-ABC-transporter-periplasmic-ligand-binding-protein
MKTWLSLACTMIATLTFSNLSLATQQTVNVTYVPTPFNLQLMVMRDQGMLDDALAKHDAKVEWHKISSGVHQAKAMASGSVDIASVMNTNSLLMAATEGNNLKVIANVARPANVFALVARPGFTGDITSLQNKAIAGAKGTVVQQMLIAQLQNNGMQQKDVKFINMGTPKAFNALMAGSVDPALLTSSFILKAQQAGATILATAEGHISPILVSTTTETFAKQHPELVEAFILAQRQAMAFIQQKPEAALAIGAKEHGISTEQAKLLCQWSALTTDIEPQDLKALYADADFLIENNLMRTGLNVSELITPTSATQLVL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

86033 : 97934

uncultured_Mediterranean_phage(25.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON48063.1\|86033_87335_+	enolase	A0A1X9I5Z8	Streptococcus_phage	5.5e-134	60.6
SON48064.1\|87496_87784_+	cell division protein	NA	NA	NA	NA
SON48065.1\|87807_88530_+	4-diphosphocytidyl-2C-methyl-D-erythritol synthase	NA	NA	NA	NA
SON48066.1\|88526_89009_+	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
SON48067.1\|89013_90063_+	pseudoruidine synthase	NA	NA	NA	NA
SON48068.1\|90069_90822_+	broad specificity 5'(3')-nucleotidase and polyphosphatase	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.4e-66	51.2
SON48069.1\|90818_91448_+	L-isoaspartate protein carboxylmethyltransferase type II	A0A1B1IU40	uncultured_Mediterranean_phage	1.5e-36	50.6
SON48070.1\|91452_92469_+	outer membrane lipoprotein	I3PV79	Clostridium_phage	5.5e-12	31.9
SON48071.1\|92542_93523_+	RNA polymerase, sigma S (sigma 38) factor	F4YCU2	Synechococcus_phage	7.6e-35	34.5
SON48072.1\|93599_96158_-	methyl-directed mismatch repair protein	A0A1V0SJ67	Klosneuvirus	2.5e-37	22.2
SON48073.1\|96251_96761_+	conserved hypothetical protein	B5TK85	Pseudomonas_phage	1.5e-26	49.4
SON48074.1\|96893_97934_+\|protease	DNA strand exchange and recombination protein with protease and nuclease activity	A0A2D1GPX2	Mycobacterium_phage	6.2e-112	61.3

DBSCAN-SWA_2

646883 : 655091

Vibrio_phage(88.89%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON48613.1\|646883_647066_-	RstR (fragment)	A0A0N9HH59	Vibrio_phage	2.5e-16	73.7
SON48614.1\|647100_647229_+	protein of unknown function	NA	NA	NA	NA
SON48615.1\|647200_648280_+	RstA	R9TRC1	Vibrio_phage	1.2e-174	80.1
SON48616.1\|648281_648617_+	putative RstB2 protein	A0A0N9HE73	Vibrio_phage	3.9e-15	35.3
SON48617.1\|648616_648856_+	conserved protein of unknown function	R9TMT7	Vibrio_phage	1.9e-08	43.0
SON48618.1\|648860_649070_+	conserved exported protein of unknown function	R9TRU5	Vibrio_phage	2.9e-05	48.3
SON48619.1\|649203_650610_+	exported protein of unknown function	R9TMT0	Vibrio_phage	1.5e-07	36.0
SON48620.1\|650613_650958_+	Accessory cholera enterotoxin	Q64EV1	Vibrio_phage	1.8e-23	44.7
SON48621.1\|650965_652372_+	Zonular occludens toxin family protein	R9TQ09	Vibrio_phage	1.9e-124	53.6
SON48622.1\|652457_652640_-	Prophage Lp2 protein 14	NA	NA	NA	NA
SON48623.1\|653012_655091_-	putative TWO-COMPONENT SENSOR PROTEIN HISTIDINE PROTEIN KINASE (DHKK, DHKJ)	A0A1V0SGX0	Hokovirus	8.8e-49	34.2

DBSCAN-SWA_3

2179148 : 2240777

Paenibacillus_phage(18.18%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON50046.1\|2179148_2179592_-\|transposase	transposase (fragment)	NA	NA	NA	NA
SON50047.1\|2179723_2180359_-\|transposase	transposase (fragment)	A0A0K2CZ57	Paenibacillus_phage	5.1e-16	26.8
SON50048.1\|2180574_2181858_-	conserved protein of unknown function	A0A0U4J920	Pseudomonas_phage	1.1e-36	32.0
SON50049.1\|2182677_2185380_-	fused acetaldehyde-CoA dehydrogenase; iron-dependent alcohol dehydrogenase; pyruvate-formate lyase deactivase	NA	NA	NA	NA
SON50050.1\|2185491_2185611_+	protein of unknown function	NA	NA	NA	NA
SON50051.1\|2186052_2186691_+	conserved hypothetical protein; putative inner membrane protein	NA	NA	NA	NA
SON50052.1\|2186815_2187667_+	putative Potassium voltage-gated channel subfamily KQT	A0A1B0Y2S3	Lactobacillus_phage	9.9e-07	34.4
SON50053.1\|2187785_2188901_-	aspartate-semialdehyde dehydrogenase, NAD(P)-binding	NA	NA	NA	NA
SON50054.1\|2189017_2190175_-	conserved protein of unknown function	NA	NA	NA	NA
SON50055.1\|2190266_2191592_-	putative Signal transduction histidine kinase	NA	NA	NA	NA
SON50056.1\|2191683_2192688_-	nucleotide associated protein	A0A1V0E8C0	Vibrio_phage	2.8e-109	60.2
SON50057.1\|2192770_2192998_+	conserved hypothetical protein	NA	NA	NA	NA
SON50058.1\|2193024_2194827_+	conserved membrane protein of unknown function	NA	NA	NA	NA
SON50059.1\|2195380_2195545_-	protein of unknown function	NA	NA	NA	NA
SON50060.1\|2195693_2196470_+	exported protein of unknown function	NA	NA	NA	NA
SON50061.1\|2196529_2198386_+	protein of unknown function	NA	NA	NA	NA
SON50062.1\|2198468_2199377_-	Histone deacetylase/AcuC/AphA family protein	A0A2K9L2T7	Tupanvirus	4.4e-13	24.5
SON50063.1\|2199593_2200280_+	Short-chain dehydrogenase/reductase SDR	NA	NA	NA	NA
SON50064.1\|2200365_2202330_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	1.7e-33	29.6
SON50065.1\|2202431_2202980_-	putative oxidoreductase	NA	NA	NA	NA
SON50066.1\|2203124_2205137_-	2,4-dienoyl-CoA reductase, NADH and FMN-linked	NA	NA	NA	NA
SON50067.1\|2205301_2207152_+\|protease	protease IV (signal peptide peptidase)	NA	NA	NA	NA
SON50068.1\|2207185_2208271_+	cytoplasmic L-asparaginase I	NA	NA	NA	NA
SON50069.1\|2208352_2208634_-	conserved hypothetical protein	NA	NA	NA	NA
SON50070.1\|2208745_2209561_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON50071.1\|2209635_2210031_-	methionine sulfoxide reductase B	NA	NA	NA	NA
SON50072.1\|2210367_2211363_+	glyceraldehyde-3-phosphate dehydrogenase A	NA	NA	NA	NA
SON50073.1\|2211451_2212336_+	conserved protein of unknown function	NA	NA	NA	NA
SON50074.1\|2212844_2214881_+	putative Methyl-accepting chemotaxis protein 1	A0A2H4J162	uncultured_Caudovirales_phage	9.3e-19	59.6
SON50075.1\|2215024_2215843_+	23S rRNA m1G745 methyltransferase	NA	NA	NA	NA
SON50076.1\|2215920_2216823_+	Transcriptional activator	D0R0F8	Streptococcus_phage	1.3e-09	21.7
SON50077.1\|2216963_2219087_+	Ferrichrome-iron receptor	NA	NA	NA	NA
SON50078.1\|2219271_2219907_+	conserved protein of unknown function	NA	NA	NA	NA
SON50079.1\|2219884_2220652_+	iron-hydroxamate transporter subunit; ATP-binding component of ABC superfamily	W6JKT0	Anomala_cuprea_entomopoxvirus	1.1e-09	23.8
SON50080.1\|2220645_2221566_+	putative ABC-type Fe3+-hydroxamate transport system, periplasmic component	NA	NA	NA	NA
SON50081.1\|2221565_2223542_+	putative ABC-type Fe3+-siderophore transport system, permease component	NA	NA	NA	NA
SON50082.1\|2223698_2224061_+	conserved protein of unknown function	NA	NA	NA	NA
SON50083.1\|2224139_2224442_+	conserved protein of unknown function	NA	NA	NA	NA
SON50084.1\|2224531_2224927_+	Lactoylglutathione lyase	NA	NA	NA	NA
SON50085.1\|2224972_2225263_+	Antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
SON50086.1\|2225370_2227269_+	conserved membrane protein of unknown function	A0A2I7QNT1	Vibrio_phage	6.0e-12	24.5
SON50087.1\|2227684_2228362_+	conserved membrane protein of unknown function	NA	NA	NA	NA
SON50088.1\|2228410_2229349_-	HTH-type transcriptional regulator, LysR-family	NA	NA	NA	NA
SON50089.1\|2229449_2230793_+	putative multidrug resistance protein	NA	NA	NA	NA
SON50090.1\|2230858_2231359_-	Acetyltransferase	NA	NA	NA	NA
SON50091.1\|2231966_2236247_-	conserved protein of unknown function	NA	NA	NA	NA
SON50092.1\|2236288_2236474_-	protein of unknown function	NA	NA	NA	NA
SON50093.1\|2236591_2237551_+\|transposase	transposase	NA	NA	NA	NA
SON50094.1\|2237414_2237585_-	protein of unknown function	NA	NA	NA	NA
SON50095.1\|2238380_2239520_+	conserved protein of unknown function	NA	NA	NA	NA
SON50096.1\|2239565_2239748_-\|transposase	transposase	NA	NA	NA	NA
SON50097.1\|2239883_2240777_-\|transposase	transposase (fragment)	A0A0K2CZ57	Paenibacillus_phage	8.7e-22	26.4

DBSCAN-SWA_4

2502462 : 2509168

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON50362.1\|2502462_2502933_-	6,7-dimethyl-8-ribityllumazine synthase (Lumazine synthase)(riboflavin synthase beta chain)	A0A2H4PQS3	Staphylococcus_phage	1.7e-32	49.3
SON50363.1\|2503174_2504287_-	3,4-dihydroxy-2-butanone 4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	3.3e-63	38.6
SON50364.1\|2504376_2505027_-	Riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.3e-35	38.1
SON50365.1\|2505033_2506146_-	fused diaminohydroxyphosphoribosylaminopyrimidine deaminase;5-amino-6-(5-phosphoribosylamino) uracil reductase	A0A1V0SE20	Indivirus	3.8e-43	32.8
SON50366.1\|2506145_2506595_-	transcriptional repressor of nrd genes	NA	NA	NA	NA
SON50367.1\|2506739_2507990_-	gamma-glutamylphosphate reductase	A0A1X9I5D4	Streptococcus_phage	1.8e-102	49.2
SON50368.1\|2508034_2509168_-	gamma-glutamate kinase	A0A1X9I5D0	Streptococcus_phage	4.2e-61	39.0

DBSCAN-SWA_5

2605412 : 2612645

Anguillid_herpesvirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON50463.1\|2605412_2605844_-	multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase	D2E8E1	Anguillid_herpesvirus	1.1e-19	37.1
SON50464.1\|2605922_2607212_-	aminopeptidase B	Q6GYZ8	Mycoplasma_phage	3.5e-32	38.3
SON50465.1\|2607403_2607604_-	conserved hypothetical protein	NA	NA	NA	NA
SON50466.1\|2607737_2608076_-	[2FE-2S] ferredoxin, electron carrer protein, believed to be involved in assembly of Fe-S clusters	NA	NA	NA	NA
SON50467.1\|2608100_2609954_-	DnaK-like molecular chaperone specific for IscU	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.5e-111	40.9
SON50468.1\|2609967_2610483_-	DnaJ-like molecular chaperone specific for IscU	NA	NA	NA	NA
SON50469.1\|2610625_2610949_-	iron-binding protein, believed to be involved in Fe-S protein formation or repair	A0A2H4N7N5	Lake_Baikal_phage	1.2e-24	49.5
SON50470.1\|2611014_2611398_-	iron-binding protein believed to be involved in Fe-S protein formation or repair; function as a scaffold for the assembly of the transiently bound Fe/S cluster	A0A218MKD1	uncultured_virus	1.4e-53	78.2
SON50471.1\|2611430_2612645_-\|tRNA	cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase)	A0A1X7C038	Faustovirus	6.3e-31	31.2

DBSCAN-SWA_6

2648252 : 2710998

Enterobacteria_phage(13.33%)

transposase,tRNA,integrase

attL 2656981:2656995|attR 2712070:2712084

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON50502.1\|2648252_2649461_+\|transposase	transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
SON50503.1\|2649521_2649653_-	protein of unknown function	NA	NA	NA	NA
SON50504.1\|2649757_2652331_-	protein disaggregation chaperone	H6X3M6	Enterobacteria_phage	4.2e-125	33.8
SON50505.1\|2652463_2653180_-	conserved hypothetical protein	NA	NA	NA	NA
SON50506.1\|2653179_2654154_-	23S rRNA pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	4.8e-05	27.0
SON50507.1\|2654290_2655016_+	putative lipoprotein	NA	NA	NA	NA
SON50508.1\|2655136_2656585_+	Amino-acid ABC transporter binding protein	NA	NA	NA	NA
SON50509.1\|2656908_2657244_+	cold shock protein associated with 30S ribosomal subunit	NA	NA	NA	NA
2656981:2656995	attL	NA	NA	NA	NA
SON50510.1\|2657320_2657464_-	protein of unknown function	NA	NA	NA	NA
SON50511.1\|2657493_2658669_+	fused chorismate mutase P; prephenate dehydratase	NA	NA	NA	NA
SON50512.1\|2658684_2659215_+	thiamin metabolism associated protein	NA	NA	NA	NA
SON50513.1\|2659239_2659536_-	DNA-binding transcriptional repressor, tryptophan-binding	NA	NA	NA	NA
SON50514.1\|2659610_2661533_-	putative Soluble lytic murein transglycosylase	K4NWI2	Pseudomonas_phage	3.1e-16	39.3
SON50515.1\|2661959_2663627_+	fused putative transporter subunits of ABC superfamily: ATP-binding components	A0A1V0SKJ1	Klosneuvirus	3.0e-39	27.1
SON50516.1\|2663742_2665065_+\|transposase	transposase	NA	NA	NA	NA
SON50517.1\|2665237_2665606_+	conserved protein of unknown function	NA	NA	NA	NA
SON50518.1\|2665617_2666673_+	putative Peptidase M23	A0A292GJG6	Xanthomonas_phage	4.1e-18	37.9
SON50519.1\|2666750_2667878_-	fused chorismate mutase T; prephenate dehydrogenase	NA	NA	NA	NA
SON50520.1\|2667892_2669119_-	3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible	A0A193H326	Shigella_phage	2.4e-86	50.6
SON50521.1\|2669183_2670854_+	sensory kinase in two-component system with YehT	Q9EYF3	Enterobacteria_phage	1.8e-169	56.6
SON50522.1\|2670861_2671584_+	response regulator in two-component system with YehU	NA	NA	NA	NA
SON50523.1\|2671665_2672649_-	beta N-acetyl-glucosaminidase	NA	NA	NA	NA
SON50524.1\|2672750_2673872_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
SON50525.1\|2673952_2674882_+	putative PTS component; possibly regulatory	NA	NA	NA	NA
SON50526.1\|2675161_2676988_+	Diguanylate cyclase/phosphodiesterase	NA	NA	NA	NA
SON50527.1\|2677090_2677441_-	conserved exported protein of unknown function	NA	NA	NA	NA
SON50528.1\|2677678_2679172_+	Carbon starvation protein, predicted membrane protein	NA	NA	NA	NA
SON50529.1\|2679298_2680621_+\|transposase	transposase	NA	NA	NA	NA
SON50530.1\|2680728_2681673_-	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein	NA	NA	NA	NA
SON50531.1\|2681734_2682166_-	FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)	NA	NA	NA	NA
SON50532.1\|2682282_2682795_-	prolipoprotein signal peptidase (signal peptidase II)	NA	NA	NA	NA
SON50533.1\|2682794_2685635_-\|tRNA	isoleucyl-tRNA synthetase	K7YVP8	Megavirus	1.1e-81	25.6
SON50534.1\|2685698_2686634_-	bifunctional riboflavin kinase and FAD synthetase	NA	NA	NA	NA
SON50535.1\|2686725_2688288_-	Protein MurJ homolog	NA	NA	NA	NA
SON50536.1\|2688545_2688806_+	30S ribosomal subunit protein S20	NA	NA	NA	NA
SON50537.1\|2688932_2689235_-	Transcriptional activator HlyU	NA	NA	NA	NA
SON50538.1\|2689362_2690253_-	DNA-binding transcriptional activator	NA	NA	NA	NA
SON50539.1\|2690654_2691803_+	NptA protein	NA	NA	NA	NA
SON50540.1\|2691973_2692252_-	Thymidylate synthase (fragment)	H9EB68	Vibrio_phage	1.5e-33	77.2
SON50541.1\|2692363_2693305_-	conserved protein of unknown function	NA	NA	NA	NA
SON50542.1\|2693305_2695345_-	conserved protein of unknown function	NA	NA	NA	NA
SON50543.1\|2695355_2696108_-	conserved protein of unknown function	NA	NA	NA	NA
SON50544.1\|2696156_2697548_-\|transposase	transposase	NA	NA	NA	NA
SON50545.1\|2697616_2698081_+\|transposase	transposase	A0A1S5RHE3	Helicobacter_phage	8.0e-35	48.9
SON50546.1\|2698081_2698348_-	protein of unknown function	NA	NA	NA	NA
SON50547.1\|2698344_2699763_-	conserved protein of unknown function	NA	NA	NA	NA
SON50548.1\|2700132_2701515_-	FOG: GGDEF domain protein	G8I7H9	Mycobacterium_phage	6.1e-06	23.2
SON50549.1\|2701508_2702033_-	Transcriptional regulator VspR	NA	NA	NA	NA
SON50550.1\|2702225_2702447_+	Transcriptional regulator, putative (fragment)	NA	NA	NA	NA
SON50551.1\|2702735_2704208_+	N-6 DNA methylase	J7I0U9	Acinetobacter_phage	4.1e-24	28.4
SON50552.1\|2704200_2705406_+	protein of unknown function	NA	NA	NA	NA
SON50553.1\|2705440_2708017_+	Type III restriction enzyme, res subunit	A0A2I7SC38	Paenibacillus_phage	1.9e-16	26.1
SON50554.1\|2708176_2709037_+	Thymidylate synthase	H9EB68	Vibrio_phage	3.0e-128	75.1
SON50555.1\|2709073_2709553_-	putative Exonuclease SbcC	NA	NA	NA	NA
SON50556.1\|2709552_2710998_-\|integrase	Putative DNA breaking-rejoining enzyme, integrase/recombinase (fragment)	NA	NA	NA	NA
2712070:2712084	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3171539 : 3179767

Leptospira_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON50995.1\|3171539_3173069_-	conserved protein of unknown function	S5VTP8	Leptospira_phage	7.9e-23	38.2
SON50996.1\|3173128_3173482_-\|transposase	transposase	S5VXZ8	Leptospira_phage	1.6e-14	43.5
SON50997.1\|3173478_3173796_-\|transposase	transposase	NA	NA	NA	NA
SON50998.1\|3174108_3174990_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.6e-38	38.2
SON50999.1\|3174986_3175535_-	dTDP-4-deoxyrhamnose-3,5-epimerase	A0A218MN57	uncultured_virus	3.3e-48	49.7
SON51000.1\|3175534_3176431_-	dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase)	K7QKA7	Escherichia_phage	1.1e-104	64.6
SON51001.1\|3176433_3177510_-	dTDP-D-glucose-4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.4e-96	50.7
SON51002.1\|3177632_3178637_-	putative lipopolysaccharide biosynthesis protein	NA	NA	NA	NA
SON51003.1\|3178636_3179767_-	NAD-dependent epimerase/dehydratase	A0A2K9L4U8	Tupanvirus	2.2e-30	28.4

DBSCAN-SWA_8

3619147 : 3673090

Escherichia_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON51413.1\|3619147_3619855_+\|transposase	transposase	A0A077SL39	Escherichia_phage	3.1e-54	50.0
SON51414.1\|3619986_3620598_-	Dimethylmenaquinone methyltransferase	NA	NA	NA	NA
SON51415.1\|3620581_3622474_-	Siderophore synthetase component	NA	NA	NA	NA
SON51416.1\|3622485_3623250_-	Achromobactin biosynthetic protein AcsB	NA	NA	NA	NA
SON51417.1\|3623242_3625096_-	IucA/IucC family protein	NA	NA	NA	NA
SON51418.1\|3625112_3626546_-	EmrB/QacA family drug resistance transporter	NA	NA	NA	NA
SON51419.1\|3626542_3627763_-	Diaminopimelate decarboxylase	A0A2K9L0W9	Tupanvirus	1.2e-13	23.9
SON51420.1\|3627755_3629525_-	AcsD protein	NA	NA	NA	NA
SON51421.1\|3629524_3630928_-	Diaminobutyrate--2-oxoglutarate aminotransferase	NA	NA	NA	NA
SON51422.1\|3631263_3632226_+	Achromobactin-binding periplasmic protein	NA	NA	NA	NA
SON51423.1\|3632229_3633243_+	Achromobactin transport system permease protein CbrB	A0A2H4IY97	uncultured_Caudovirales_phage	4.6e-11	24.4
SON51424.1\|3633235_3634267_+	Achromobactin transport system permease protein CbrC	NA	NA	NA	NA
SON51425.1\|3634269_3635082_+	iron-enterobactin transporter subunit; ATP-binding component of ABC superfamily	W6JKT0	Anomala_cuprea_entomopoxvirus	5.7e-12	28.8
SON51426.1\|3635047_3635875_+	conserved protein of unknown function	NA	NA	NA	NA
SON51427.1\|3635902_3637993_-	TonB-dependent receptor	NA	NA	NA	NA
SON51428.1\|3638240_3639221_-\|transposase	transposase	NA	NA	NA	NA
SON51429.1\|3640217_3643712_+	Relaxase TraI (fragment)	NA	NA	NA	NA
SON51430.1\|3644518_3645382_-	ParB-like partition protein (fragment)	A0A0F7L836	uncultured_marine_virus	3.7e-17	33.7
SON51431.1\|3646262_3646595_+	Toxin HigB-2	NA	NA	NA	NA
SON51432.1\|3646581_3646896_+	Antitoxin igA-2	NA	NA	NA	NA
SON51433.1\|3647311_3647803_+	Conserved membrane protein	NA	NA	NA	NA
SON51434.1\|3648398_3649931_+\|transposase	transposase	K4I413	Acidithiobacillus_phage	2.9e-113	42.8
SON51435.1\|3649940_3650681_+	conserved protein of unknown function	K4HZD4	Acidithiobacillus_phage	1.2e-48	44.8
SON51436.1\|3650825_3651293_+	conserved protein of unknown function	NA	NA	NA	NA
SON51437.1\|3651424_3651913_+	conserved protein of unknown function	NA	NA	NA	NA
SON51438.1\|3652052_3652121_-	protein of unknown function	NA	NA	NA	NA
SON51439.1\|3652176_3652770_+\|transposase	transposase	NA	NA	NA	NA
SON51440.1\|3652957_3653362_+	S-adenosylhomocysteine hydrolase	NA	NA	NA	NA
SON51441.1\|3653364_3654306_+	conserved protein of unknown function	NA	NA	NA	NA
SON51442.1\|3654313_3656908_+	Type I restriction-modification system N6-methylase	A0A2H4PQP4	Staphylococcus_phage	1.6e-92	41.0
SON51443.1\|3656900_3658160_+	Type I restriction modification system DNA specificity subunit Hsds	NA	NA	NA	NA
SON51444.1\|3658321_3661438_+	Type I restriction modification system deoxyribonuclease subunit HsdR	NA	NA	NA	NA
SON51445.1\|3662048_3663023_-	putative bacteriophage abortive infection protein	NA	NA	NA	NA
SON51446.1\|3663248_3663380_+	protein of unknown function	NA	NA	NA	NA
SON51447.1\|3663390_3663507_-	protein of unknown function	NA	NA	NA	NA
SON51448.1\|3663703_3663919_+	conserved protein of unknown function	NA	NA	NA	NA
SON51449.1\|3663878_3664190_+	protein of unknown function	NA	NA	NA	NA
SON51450.1\|3664186_3664867_+	conserved protein of unknown function	NA	NA	NA	NA
SON51451.1\|3666229_3666391_+	conserved protein of unknown function	NA	NA	NA	NA
SON51452.1\|3666387_3666624_-	DinI-like protein MsgA	NA	NA	NA	NA
SON51453.1\|3666763_3666973_-	conserved protein of unknown function	NA	NA	NA	NA
SON51454.1\|3667312_3667915_+	conserved protein of unknown function	NA	NA	NA	NA
SON51455.1\|3667962_3668229_+	protein of unknown function	Q2A0A7	Sodalis_phage	1.7e-05	54.5
SON51456.1\|3668046_3668628_-\|transposase	transposase	A0A1X9I6E7	Streptococcus_phage	1.1e-20	44.1
SON51457.1\|3668760_3668880_-	protein of unknown function	NA	NA	NA	NA
SON51458.1\|3668975_3669392_-	putative transcriptional regulator	NA	NA	NA	NA
SON51459.1\|3669400_3669715_-	conserved hypothetical protein	NA	NA	NA	NA
SON51460.1\|3669914_3670526_+	putative resolvase of Tn3 transposon family	A0A0A8WJD4	Clostridium_phage	1.0e-05	27.4
SON51461.1\|3671302_3672166_+	putative exported nuclease	NA	NA	NA	NA
SON51462.1\|3672352_3673090_+\|transposase	transposase	A0A077SL39	Escherichia_phage	6.1e-53	50.0

DBSCAN-SWA_9

3686770 : 3742789

Escherichia_phage(26.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SON51484.1\|3686770_3687079_+\|transposase	transposase (fragment)	A4KWT9	Enterobacteria_phage	1.0e-14	53.2
SON51485.1\|3687075_3687813_+\|transposase	transposase	A0A077SL39	Escherichia_phage	6.5e-55	50.5
SON51486.1\|3688005_3689211_+	protein of unknown function	NA	NA	NA	NA
SON51487.1\|3689251_3689992_-	conserved protein of unknown function	K4HZD4	Acidithiobacillus_phage	1.2e-48	44.8
SON51488.1\|3690001_3691534_-\|transposase	transposase	K4I413	Acidithiobacillus_phage	2.9e-113	42.8
SON51489.1\|3691922_3692471_+	TIR protein (fragment)	NA	NA	NA	NA
SON51490.1\|3692521_3693103_-	conserved protein of unknown function	NA	NA	NA	NA
SON51491.1\|3693102_3693306_-	conserved protein of unknown function	NA	NA	NA	NA
SON51492.1\|3693912_3694413_-	protein of unknown function	NA	NA	NA	NA
SON51493.1\|3694950_3695166_+	protein of unknown function	NA	NA	NA	NA
SON51494.1\|3695317_3695782_-\|transposase	transposase	A0A1S5RHE3	Helicobacter_phage	8.0e-35	48.9
SON51495.1\|3695850_3697242_+\|transposase	transposase	A0A2I7RKG5	Vibrio_phage	1.6e-09	23.8
SON51496.1\|3697391_3697658_+	protein of unknown function	NA	NA	NA	NA
SON51497.1\|3697778_3697970_+	protein of unknown function	NA	NA	NA	NA
SON51498.1\|3698088_3698331_+	protein of unknown function	NA	NA	NA	NA
SON51499.1\|3698378_3698750_+	conserved protein of unknown function	NA	NA	NA	NA
SON51500.1\|3698742_3699063_+	conserved membrane protein of unknown function	NA	NA	NA	NA
SON51501.1\|3699065_3701591_+	putative Type IV secretion system protein B4	NA	NA	NA	NA
SON51502.1\|3701587_3702379_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON51503.1\|3702359_3702584_+	protein of unknown function	NA	NA	NA	NA
SON51504.1\|3702594_3703542_+	conserved membrane protein of unknown function	NA	NA	NA	NA
SON51505.1\|3703546_3704263_+	conserved protein of unknown function	NA	NA	NA	NA
SON51506.1\|3704262_3705117_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON51507.1\|3705128_3706382_+	putative conjugal transfer protein TrbI	NA	NA	NA	NA
SON51508.1\|3706378_3706732_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON51509.1\|3706728_3707472_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON51510.1\|3707472_3708915_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON51511.1\|3708924_3710046_+	conserved protein of unknown function	NA	NA	NA	NA
SON51512.1\|3710032_3710779_+	conserved exported protein of unknown function	NA	NA	NA	NA
SON51513.1\|3710741_3711974_+	protein of unknown function	NA	NA	NA	NA
SON51514.1\|3712059_3712323_-	protein of unknown function	NA	NA	NA	NA
SON51515.1\|3712452_3712665_-	protein of unknown function	NA	NA	NA	NA
SON51516.1\|3712740_3713136_-	protein of unknown function	NA	NA	NA	NA
SON51517.1\|3713149_3713494_-	conserved protein of unknown function	NA	NA	NA	NA
SON51518.1\|3713510_3713774_-	protein of unknown function	NA	NA	NA	NA
SON51519.1\|3713882_3714095_+	conserved protein of unknown function	NA	NA	NA	NA
SON51520.1\|3714075_3714573_+	conserved protein of unknown function	NA	NA	NA	NA
SON51521.1\|3714829_3715750_-	Antirestriction protein	A0A1V0EBY3	Caulobacter_phage	4.0e-46	40.9
SON51522.1\|3715727_3716465_-\|transposase	transposase	A0A077SL39	Escherichia_phage	1.4e-54	50.5
SON51523.1\|3716843_3717602_+	Transcriptional regulatory protein RstA	NA	NA	NA	NA
SON51524.1\|3717779_3718022_+	protein of unknown function	NA	NA	NA	NA
SON51525.1\|3717964_3718285_+\|transposase	transposase (fragment)	NA	NA	NA	NA
SON51526.1\|3718483_3718648_+	protein of unknown function	NA	NA	NA	NA
SON51527.1\|3718620_3718779_+	protein of unknown function	NA	NA	NA	NA
SON51528.1\|3718655_3718991_+	protein of unknown function	NA	NA	NA	NA
SON51529.1\|3718990_3719170_+	protein of unknown function	NA	NA	NA	NA
SON51530.1\|3719460_3720051_+	conserved protein of unknown function	A0A1X9I6E7	Streptococcus_phage	1.7e-26	43.1
SON51531.1\|3720047_3720185_+	protein of unknown function	NA	NA	NA	NA
SON51532.1\|3720290_3720443_-	protein of unknown function	NA	NA	NA	NA
SON51533.1\|3720459_3722409_-	Colicin V secretion atp-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.4e-08	28.6
SON51534.1\|3722405_3723677_-	Secretion protein	NA	NA	NA	NA
SON51535.1\|3723667_3725047_-	Microcin secretion/processing ATP-binding protein	NA	NA	NA	NA
SON51536.1\|3725112_3725316_-	conserved protein of unknown function	NA	NA	NA	NA
SON51537.1\|3725361_3725511_+	protein of unknown function	NA	NA	NA	NA
SON51538.1\|3725592_3725778_-	protein of unknown function	NA	NA	NA	NA
SON51539.1\|3725783_3726086_+\|transposase	transposase (fragment)	NA	NA	NA	NA
SON51540.1\|3726283_3726442_+	protein of unknown function	NA	NA	NA	NA
SON51541.1\|3726686_3726854_-	conserved protein of unknown function	NA	NA	NA	NA
SON51542.1\|3726948_3728541_-	conserved exported protein of unknown function	Q91BI7	Spodoptera_litura_multicapsid_nucleopolyhedrovirus	1.3e-20	29.6
SON51543.1\|3728680_3728815_+	protein of unknown function	NA	NA	NA	NA
SON51544.1\|3728764_3729142_-\|transposase	transposase	NA	NA	NA	NA
SON51545.1\|3729249_3729366_-	protein of unknown function	NA	NA	NA	NA
SON51546.1\|3729543_3730020_-	Insertion sequence IS21 putative ATP-binding protein (fragment)	A0A2L1IVB6	Escherichia_phage	7.6e-49	63.8
SON51547.1\|3730050_3730326_-\|transposase	transposase (fragment)	NA	NA	NA	NA
SON51548.1\|3730402_3730720_-	protein of unknown function	NA	NA	NA	NA
SON51549.1\|3730774_3731512_+\|transposase	transposase	A0A077SL39	Escherichia_phage	6.5e-55	50.5
SON51550.1\|3731636_3731924_-	Lytic transglycosylase PilT (fragment)	NA	NA	NA	NA
SON51551.1\|3731985_3732321_-	conserved protein of unknown function	NA	NA	NA	NA
SON51552.1\|3732405_3732792_-	conserved protein of unknown function	NA	NA	NA	NA
SON51553.1\|3732815_3733160_-	conserved exported protein of unknown function	NA	NA	NA	NA
SON51554.1\|3733648_3733840_-	protein of unknown function	NA	NA	NA	NA
SON51555.1\|3733818_3735642_-	ParB-like partition protein	A0A0F7L836	uncultured_marine_virus	3.0e-16	33.1
SON51556.1\|3736363_3737548_+	Abortive infection protein, internal deletion	NA	NA	NA	NA
SON51557.1\|3737550_3738069_+	conserved protein of unknown function	NA	NA	NA	NA
SON51558.1\|3738276_3738603_-	conserved protein of unknown function	NA	NA	NA	NA
SON51559.1\|3738614_3738779_-	protein of unknown function	NA	NA	NA	NA
SON51560.1\|3738814_3739279_-	conserved protein of unknown function	NA	NA	NA	NA
SON51561.1\|3739294_3739765_-	conserved protein of unknown function	NA	NA	NA	NA
SON51562.1\|3740290_3740527_-	DinI-like protein MsgA	NA	NA	NA	NA
SON51563.1\|3741173_3741776_+	conserved protein of unknown function	NA	NA	NA	NA
SON51564.1\|3741823_3742789_+\|transposase	putative transposase	Q2A0A7	Sodalis_phage	1.5e-64	51.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LT960613

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. LT960611

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection