CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483308	Staphylococcus aureus strain NCTC13137 genome assembly, chromosome: 1	4 crisprs	cas3,DEDDh,DinG,csa3,WYL	0	2	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483308_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483308_1

391104-391205

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483308_1

>merge|LS483308|1|391104-391205|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>LS483308|1|1|391104-391205|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
LS483308.1\|SQE63089.1\|401081_401354_-\|transposase	unknown	unknown	gnl\|CDD\|225511
LS483308.1\|SQE63074.1\|382988_383615_-\|lipoprotein	unknown	unknown	gnl\|CDD\|380196
LS483308.1\|SQE63078.1\|388021_388777_+\|Chromate-reductase	unknown	unknown	gnl\|CDD\|380322
LS483308.1\|SQE63084.1\|394598_395867_+\|Xanthine-permease	unknown	unknown	gnl\|CDD\|274468
LS483308.1\|SQE63079.1\|388856_390245_-\|Sodium:dicarboxylate-symporter-family-protein	unknown	unknown	gnl\|CDD\|224736
LS483308.1\|SQE63077.1\|386960_387530_-\|Alkyl-hydroperoxide-reductase-protein-C	unknown	unknown	gnl\|CDD\|211789
LS483308.1\|SQE63071.1\|381702_382284_+\|truncated-phosphoglycerate-mutase-family-protein	unknown	unknown	gnl\|CDD\|223483
LS483308.1\|SQE63075.1\|383687_385307_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483308.1\|SQE63087.1\|399049_399586_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483308.1\|SQE63080.1\|391221_392178_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|235334
LS483308.1\|SQE63088.1\|399978_400683_-\|Phage-protein	unknown	unknown	gnl\|CDD\|367091
LS483308.1\|SQE63072.1\|382349_382736_-\|membrane-spanning-protein	unknown	unknown	unknown
LS483308.1\|SQE63085.1\|395904_397371_+\|Inosine-5-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
LS483308.1\|SQE63086.1\|397395_398937_+\|GMP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|234614
LS483308.1\|SQE63073.1\|382794_382920_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483308.1\|SQE63083.1\|394020_394599_+\|Xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
LS483308.1\|SQE63082.1\|393100_393508_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|378584
LS483308.1\|SQE63070.1\|381022_381274_+\|transglycosylase-associated-family-protein	unknown	unknown	gnl\|CDD\|225170
LS483308.1\|SQE63076.1\|385421_386945_-\|Alkyl-hydroperoxide-reductase-protein-F	unknown	unknown	gnl\|CDD\|237942
LS483308.1\|SQE63081.1\|392295_392958_-\|Uncharacterised-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
LS483308.1\|SQE63089.1\|401081_401354_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
LS483308.1\|SQE63074.1\|382988_383615_-\|lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
LS483308.1\|SQE63078.1\|388021_388777_+\|Chromate-reductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.05628e-88
LS483308.1\|SQE63084.1\|394598_395867_+\|Xanthine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	5.74823e-170
LS483308.1\|SQE63079.1\|388856_390245_-\|Sodium:dicarboxylate-symporter-family-protein	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
LS483308.1\|SQE63077.1\|386960_387530_-\|Alkyl-hydroperoxide-reductase-protein-C	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
LS483308.1\|SQE63071.1\|381702_382284_+\|truncated-phosphoglycerate-mutase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
LS483308.1\|SQE63082.1\|393100_393508_-\|transcriptional-regulator	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
LS483308.1\|SQE63088.1\|399978_400683_-\|Phage-protein	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
LS483308.1\|SQE63085.1\|395904_397371_+\|Inosine-5-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
LS483308.1\|SQE63086.1\|397395_398937_+\|GMP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
LS483308.1\|SQE63080.1\|391221_392178_-\|DNA-binding-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
LS483308.1\|SQE63083.1\|394020_394599_+\|Xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
LS483308.1\|SQE63070.1\|381022_381274_+\|transglycosylase-associated-family-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.89532e-08
LS483308.1\|SQE63076.1\|385421_386945_-\|Alkyl-hydroperoxide-reductase-protein-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0

>LS483308.1|SQE63079.1|388856_390245_-|Sodium:dicarboxylate-symporter-family-protein
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>LS483308.1|SQE63078.1|388021_388777_+|Chromate-reductase
MSDHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYNQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>LS483308.1|SQE63077.1|386960_387530_-|Alkyl-hydroperoxide-reductase-protein-C
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>LS483308.1|SQE63076.1|385421_386945_-|Alkyl-hydroperoxide-reductase-protein-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRSTDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>LS483308.1|SQE63075.1|383687_385307_-|Uncharacterised-protein
MLDVHFIYPRKLQNACEYFNLPTQKEGFEVTMHALRPENIHKIYHDMDKTEQKFIETLISNGNPVTIINKRDVNILKLTNHLGFVYQINEDEFFVNNLFLSYINSEVLDSTYGEFEALDTIDHMHLNDEVFRVRQHTRLNDVTLEHALLLKTNDELKTICRQYGIKGFSNKNKQNLVELIMTVFFNNNHIIEQVFSNATLFEFDILSSILESDDNYRLNNELTKFEKLQLINFDNFLTSHFYYYYDFEYDCLILPNDVRKHIENFVNQVGNGDFEKAVNQFVDEQTIEKSLAEFENALELSFMDDEVDLDMLLKDDDFEDFGTTDSLRSDAITQLISEIKKGLIDKKDILPLRIILGSVNLYGILSTNHLLYLLQRFYDATFSKEELQYSLDTLAGTELYYVEDDFVFHPVLFDVVESEASGIDISDDGYYVPASVEELIYYDRHHYLKSDQAIKAFTSYLRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLIQPIMQLFIDNAILNNVQNDALLIEKVTHARNHLRLWSLQGHREIPN
>LS483308.1|SQE63074.1|382988_383615_-|lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>LS483308.1|SQE63073.1|382794_382920_+|Uncharacterised-protein
MRQLMGDFGIDREFKAIKKASNSNMLLDAQMMTLAKLISHF
>LS483308.1|SQE63072.1|382349_382736_-|membrane-spanning-protein
MMKVRITFIILAILSTIVCLFLTAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFVSAIITLAIGGKSVDKNDFH
>LS483308.1|SQE63071.1|381702_382284_+|truncated-phosphoglycerate-mutase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>LS483308.1|SQE63070.1|381022_381274_+|transglycosylase-associated-family-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWLGGTLLGQWGPEIGRIYILPALIGSIILIAIVTLILRAMRK
>LS483308.1|SQE63080.1|391221_392178_-|DNA-binding-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>LS483308.1|SQE63081.1|392295_392958_-|Uncharacterised-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>LS483308.1|SQE63082.1|393100_393508_-|transcriptional-regulator
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>LS483308.1|SQE63083.1|394020_394599_+|Xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>LS483308.1|SQE63084.1|394598_395867_+|Xanthine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>LS483308.1|SQE63085.1|395904_397371_+|Inosine-5-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>LS483308.1|SQE63086.1|397395_398937_+|GMP-synthase-(glutamine-hydrolyzing)
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCECKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>LS483308.1|SQE63087.1|399049_399586_-|Uncharacterised-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>LS483308.1|SQE63088.1|399978_400683_-|Phage-protein
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>LS483308.1|SQE63089.1|401081_401354_-|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Crispr_ID: LS483308_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483308_2

2164351-2164436

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of LS483308_2

>merge|LS483308|2|2164351-2164436|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTCTTATGCA

>LS483308|2|2|2164351-2164436|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTCTTATGCA

Protein	Signature genes	Signature genes Name	Protein_function
LS483308.1\|SQE64717.1\|2168377_2170183_-\|glucosamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
LS483308.1\|SQE64715.1\|2166438_2167296_-\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|223635
LS483308.1\|SQE64714.1\|2166225_2166318_+\|erm-leader-peptide	unknown	unknown	unknown
LS483308.1\|SQE64705.1\|2155667_2156111_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	unknown	unknown	gnl\|CDD\|223854
LS483308.1\|SQE64723.1\|2184162_2185518_-\|Phosphoglucosamine-mutase-/-FemD,-factor-involved-in-methicillin-resistance	unknown	unknown	gnl\|CDD\|237670
LS483308.1\|SQE64710.1\|2160860_2161526_-\|oxidoreductase-ylbE	unknown	unknown	gnl\|CDD\|187554
LS483308.1\|SQE64709.1\|2159486_2160425_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
LS483308.1\|SQE64718.1\|2170863_2172402_+\|PTS-system,-mannitol-specific-IIBC-component	unknown	unknown	gnl\|CDD\|225123
LS483308.1\|SQE64716.1\|2167363_2168146_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
LS483308.1\|SQE64708.1\|2159225_2159456_-\|membrane-protein	unknown	unknown	unknown
LS483308.1\|SQE64721.1\|2175014_2176121_+\|Mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
LS483308.1\|SQE64707.1\|2157180_2158554_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
LS483308.1\|SQE64712.1\|2161999_2162977_+\|Cobalt-zinc-cadmium-resistance-protein	unknown	unknown	gnl\|CDD\|224151
LS483308.1\|SQE64711.1\|2161677_2161998_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
LS483308.1\|SQE64719.1\|2172436_2174569_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234
LS483308.1\|SQE64706.1\|2156310_2156724_-\|thiol-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|225556
LS483308.1\|SQE64713.1\|2163242_2164334_+\|Lytic-regulatory-protein	unknown	unknown	unknown
LS483308.1\|SQE64722.1\|2176439_2183885_-\|FmtB-protein	unknown	unknown	gnl\|CDD\|275089
LS483308.1\|SQE64704.1\|2154836_2155547_+\|Purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
LS483308.1\|SQE64720.1\|2174580_2175015_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014

Protein	Function_ID	Function_description	E-value
LS483308.1\|SQE64717.1\|2168377_2170183_-\|glucosamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
LS483308.1\|SQE64715.1\|2166438_2167296_-\|Putative-cytosolic-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.00207e-59
LS483308.1\|SQE64719.1\|2172436_2174569_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.61815e-67
LS483308.1\|SQE64705.1\|2155667_2156111_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
LS483308.1\|SQE64710.1\|2160860_2161526_-\|oxidoreductase-ylbE	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
LS483308.1\|SQE64709.1\|2159486_2160425_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
LS483308.1\|SQE64718.1\|2170863_2172402_+\|PTS-system,-mannitol-specific-IIBC-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
LS483308.1\|SQE64716.1\|2167363_2168146_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
LS483308.1\|SQE64721.1\|2175014_2176121_+\|Mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
LS483308.1\|SQE64707.1\|2157180_2158554_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
LS483308.1\|SQE64712.1\|2161999_2162977_+\|Cobalt-zinc-cadmium-resistance-protein	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.26159e-107
LS483308.1\|SQE64711.1\|2161677_2161998_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.83702e-17
LS483308.1\|SQE64723.1\|2184162_2185518_-\|Phosphoglucosamine-mutase-/-FemD,-factor-involved-in-methicillin-resistance	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
LS483308.1\|SQE64706.1\|2156310_2156724_-\|thiol-disulfide-oxidoreductase	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
LS483308.1\|SQE64722.1\|2176439_2183885_-\|FmtB-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.31178e-108
LS483308.1\|SQE64704.1\|2154836_2155547_+\|Purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
LS483308.1\|SQE64720.1\|2174580_2175015_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62

>LS483308.1|SQE64713.1|2163242_2164334_+|Lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>LS483308.1|SQE64712.1|2161999_2162977_+|Cobalt-zinc-cadmium-resistance-protein
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>LS483308.1|SQE64711.1|2161677_2161998_+|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein
MSEQYSEIHTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>LS483308.1|SQE64710.1|2160860_2161526_-|oxidoreductase-ylbE
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>LS483308.1|SQE64709.1|2159486_2160425_-|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>LS483308.1|SQE64708.1|2159225_2159456_-|membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>LS483308.1|SQE64707.1|2157180_2158554_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>LS483308.1|SQE64706.1|2156310_2156724_-|thiol-disulfide-oxidoreductase
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>LS483308.1|SQE64705.1|2155667_2156111_-|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>LS483308.1|SQE64704.1|2154836_2155547_+|Purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>LS483308.1|SQE64714.1|2166225_2166318_+|erm-leader-peptide
MTFGSIVAILCALFVIFFIPYMEKKDKKKK
>LS483308.1|SQE64715.1|2166438_2167296_-|Putative-cytosolic-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITTFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>LS483308.1|SQE64716.1|2167363_2168146_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>LS483308.1|SQE64717.1|2168377_2170183_-|glucosamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLSELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>LS483308.1|SQE64718.1|2170863_2172402_+|PTS-system,-mannitol-specific-IIBC-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>LS483308.1|SQE64719.1|2172436_2174569_+|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFNYPRLFENVRLALNDCWPDLIFPESEIAFVVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>LS483308.1|SQE64720.1|2174580_2175015_+|PTS-system-mannitol-specific-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>LS483308.1|SQE64721.1|2175014_2176121_+|Mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>LS483308.1|SQE64722.1|2176439_2183885_-|FmtB-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDVNHVETANRASQADIDGLVTKLQAALIDNQAAIAELDAKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTAPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEISKIENITDSTQTKMDAYNDVKQAATARKTQNATVSNATNEEVAEADAAVDAAQKQGLHDIQVVKSKQEVADTKSKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKQAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQVVVTANADIDNAAANADVDNAKTTNEATIAAITPDANVKPTAKQAIADKVQAQETAIDANNGSTTEEKTAAKQQVQTEKTTADAAIDAAHTNAEVEAAKNAEIAKIEAIQPATTTKDNAKEAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANNNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITTILNNKLQAIQATPDATNEEKQAADAEANTENGKAIQAIAAATTNADVDEAKANAEAAINAVTPKVVKKQSAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDQAKDAGKNSIQSTQPATAVKSNAKNDVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILSDNTTTNEEKGKDIEPVRATYEEGLNNINTANTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDHSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTTTAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTSNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQTSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE
>LS483308.1|SQE64723.1|2184162_2185518_-|Phosphoglucosamine-mutase-/-FemD,-factor-involved-in-methicillin-resistance
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK

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Crispr_ID: LS483308_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483308_4

2400090-2400183

Orphan

Consensus_repeat	Method
GCGCATGCATAAAAGCCCCTAACAACCAGAGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483308_4

>merge|LS483308|4|2400090-2400183|CRISPRCasFinder
GCGCATGCATAAAAGCCCCTAACAACCAGAGGTCACTTCGCTTCGGTTCGCCTGCGCTTTTGCGCATGCATAAAAGCCCCTAACAACCAAAGGT

>LS483308|4|4|2400090-2400183|CRISPRCasFinder
GCGCATGCATAAAAGCCCCTAACAACCAGAGGT	CACTTCGCTTCGGTTCGCCTGCGCTTTT
GCGCATGCATAAAAGCCCCTAACAACCAAAGGT

Protein	Signature genes	Signature genes Name	Protein_function
LS483308.1\|SQE64927.1\|2388177_2389212_-\|Thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|223566
LS483308.1\|SQE64941.1\|2403635_2404805_-\|nitrite-extrusion-protein	unknown	unknown	gnl\|CDD\|225133
LS483308.1\|SQE64944.1\|2406966_2407419_-\|nreA-protein	unknown	unknown	gnl\|CDD\|376570
LS483308.1\|SQE64942.1\|2405232_2405886_-\|Two-component-response-regulator	unknown	unknown	gnl\|CDD\|225107
LS483308.1\|SQE64938.1\|2401674_2402040_-\|exported-protein	unknown	unknown	gnl\|CDD\|371476
LS483308.1\|SQE64928.1\|2389443_2389875_-\|membrane-protein	unknown	unknown	gnl\|CDD\|378551
LS483308.1\|SQE64931.1\|2392188_2393133_+\|Magnesium-and-cobalt-transport-protein-corA	unknown	unknown	gnl\|CDD\|213361
LS483308.1\|SQE64936.1\|2399576_2399933_+\|exported-protein	unknown	unknown	gnl\|CDD\|374445
LS483308.1\|SQE64935.1\|2398889_2399312_+\|General-stress-protein-26	unknown	unknown	gnl\|CDD\|226389
LS483308.1\|SQE64934.1\|2396713_2398819_+\|AraC-family-regulatory-protein	unknown	unknown	gnl\|CDD\|225117
LS483308.1\|SQE64932.1\|2393217_2394660_-\|PTS-system,-sucrose-specific-IIB-component-/-PTS-system,-sucrose-specific-IIC-component	unknown	unknown	gnl\|CDD\|131051
LS483308.1\|SQE64945.1\|2407438_2408116_-\|Respiratory-nitrate-reductase-gamma-chain	unknown	unknown	gnl\|CDD\|376889
LS483308.1\|SQE64940.1\|2403106_2403529_+\|small-heat-shock-protein	unknown	unknown	gnl\|CDD\|107228
LS483308.1\|SQE64929.1\|2390081_2391359_-\|Phage-infection-protein	unknown	unknown	gnl\|CDD\|224428
LS483308.1\|SQE64933.1\|2394842_2395226_+\|type-II-DNA-modification-enzyme	unknown	unknown	gnl\|CDD\|377982
LS483308.1\|SQE64930.1\|2391519_2392143_+\|Transcriptional-regulator,-TetR-family	unknown	unknown	gnl\|CDD\|224228
LS483308.1\|SQE64939.1\|2402437_2402956_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
LS483308.1\|SQE64946.1\|2408108_2408684_-\|respiratory-nitrate-reductase-subunit-delta	unknown	unknown	gnl\|CDD\|225091
LS483308.1\|SQE64943.1\|2405908_2406943_-\|Two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
LS483308.1\|SQE64937.1\|2400215_2401493_-\|Proton/glutamate-symport-protein;-Sodium/glutamate-symport-protein	unknown	unknown	gnl\|CDD\|183075

Protein	Function_ID	Function_description	E-value
LS483308.1\|SQE64927.1\|2388177_2389212_-\|Thioredoxin-disulfide-reductase	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	8.72251e-71
LS483308.1\|SQE64941.1\|2403635_2404805_-\|nitrite-extrusion-protein	gnl\|CDD\|225133	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism].	8.79727e-124
LS483308.1\|SQE64944.1\|2406966_2407419_-\|nreA-protein	gnl\|CDD\|376570	pfam01590, GAF, GAF domain. This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.	9.51589e-08
LS483308.1\|SQE64942.1\|2405232_2405886_-\|Two-component-response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.78552e-77
LS483308.1\|SQE64938.1\|2401674_2402040_-\|exported-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	2.28129e-12
LS483308.1\|SQE64928.1\|2389443_2389875_-\|membrane-protein	gnl\|CDD\|378551	pfam11070, DUF2871, Protein of unknown function (DUF2871). This family of proteins has no known function.	4.67525e-52
LS483308.1\|SQE64931.1\|2392188_2393133_+\|Magnesium-and-cobalt-transport-protein-corA	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.84965e-109
LS483308.1\|SQE64936.1\|2399576_2399933_+\|exported-protein	gnl\|CDD\|374445	pfam16230, DUF4889, Domain of unknown function (DUF4889). This family consists of uncharacterized proteins around 110 residues in length and is mainly found in various Staphylococcus aureus species. The function of this family is unknown.	5.76146e-27
LS483308.1\|SQE64935.1\|2398889_2399312_+\|General-stress-protein-26	gnl\|CDD\|226389	COG3871, COG3871, Uncharacterized stress protein (general stress protein 26) [General function prediction only].	1.42489e-53
LS483308.1\|SQE64934.1\|2396713_2398819_+\|AraC-family-regulatory-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.42588e-18
LS483308.1\|SQE64932.1\|2393217_2394660_-\|PTS-system,-sucrose-specific-IIB-component-/-PTS-system,-sucrose-specific-IIC-component	gnl\|CDD\|131051	TIGR01996, Includes:_Phosphotransferase_enzyme_IIB_component, PTS system, sucrose-specific IIBC component. This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).	0
LS483308.1\|SQE64945.1\|2407438_2408116_-\|Respiratory-nitrate-reductase-gamma-chain	gnl\|CDD\|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	1.46787e-109
LS483308.1\|SQE64940.1\|2403106_2403529_+\|small-heat-shock-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	6.4521e-27
LS483308.1\|SQE64929.1\|2390081_2391359_-\|Phage-infection-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	1.08197e-61
LS483308.1\|SQE64933.1\|2394842_2395226_+\|type-II-DNA-modification-enzyme	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	1.86952e-23
LS483308.1\|SQE64930.1\|2391519_2392143_+\|Transcriptional-regulator,-TetR-family	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.57915e-11
LS483308.1\|SQE64939.1\|2402437_2402956_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.12709e-19
LS483308.1\|SQE64946.1\|2408108_2408684_-\|respiratory-nitrate-reductase-subunit-delta	gnl\|CDD\|225091	COG2180, NarJ, Nitrate reductase delta subunit [Energy production and conversion].	2.05624e-64
LS483308.1\|SQE64943.1\|2405908_2406943_-\|Two-component-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.62845e-74
LS483308.1\|SQE64937.1\|2400215_2401493_-\|Proton/glutamate-symport-protein;-Sodium/glutamate-symport-protein	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	2.81111e-168

>LS483308.1|SQE64936.1|2399576_2399933_+|exported-protein
MKKKKGFGLGISLIAIMLIVCIVLVIMMMTGGKKDTYYGIMKDNATIEKMISEKDESIEKNVKLPSDADVKVKKGDFVIVYKLADSDKIVKVKKVDHDDVPHGLMMKIHDMGKMHMKH
>LS483308.1|SQE64935.1|2398889_2399312_+|General-stress-protein-26
MSNSQAIQAIENVLATSKVGVLSTAYNNKPNSRYMVFYNDGLTLYTKTNIHSAKVKEIKDNPAAYVLLGYNDTTTRSFVEMEATIEVVTDQKVIDWLWETQDKSFFSSKEDPELCVLKVTPQSVKLMNDKSLDTPIKIDL
>LS483308.1|SQE64934.1|2396713_2398819_+|AraC-family-regulatory-protein
MTCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINHGENIIELMIPVFYFYQQDDDFFNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIGQSIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNIDAHLSLKDIAMHCNISESYCSNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFKNYLHFSPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDFNPKDRSQRAKVFVRFSNFNELFQFIFNEYYDINFEHLPKPVVFIDDIHDIEISQTNYNLLNRCFEKLFEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKLVKFMLVFCSNSMTAEEIHLCHLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIENSKTATHLITKNQHYHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNPIQLSDIVYHLIALLRYGGGISYQLLDDHSNYISLYNKYGSPLPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYHFLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEHGSIQHLLPISDQLVYIEKEILDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFKPS
>LS483308.1|SQE64933.1|2394842_2395226_+|type-II-DNA-modification-enzyme
MKERGYIEQLWREEKYHVLLHSQQSYQMIRNALKTDLSLHQVQQMIDDALLIEPSIGSVCNAFDHMWGYFKKCANEEERKQSKLLKADFINSKIDTQTLLDFLAELANKYDVQYLLQSRVLNTKRKR
>LS483308.1|SQE64932.1|2393217_2394660_-|PTS-system,-sucrose-specific-IIB-component-/-PTS-system,-sucrose-specific-IIC-component
MNYKQSAEEILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEALNNMDVVKGTFSTGGQYQIIIGSGTVNKVFSELEKLTGKEASTTSEVKAQSAKNMNPVQRFVKMLSDIFVPIIPAIVAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMINVFANAPFTLLPILIGFSAAKRFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIPYWDVFGLHINQVGYQGQVLPMLVAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAFLTFSFVGPITRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIVITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNVAQGGAAIAAFFIIKQNKKLKGVASAAGISALLGITEPAMFGVNLKLRYPFIGAIVGSGIGSAYIAFFKVKAIALGTAGLPGFISINPVHAGWLHYFVGMTISFIIAITVTLILSKRKANKEVVE
>LS483308.1|SQE64931.1|2392188_2393133_+|Magnesium-and-cobalt-transport-protein-corA
MITSFRHSEDIDKHIIKTPLDHTASWINVVEPDREEIENLMEQYNIPEDFIRDPLDSEESSRIEYDEDTGYSLIIIDLPIVNSTNRSVLSFVTIPLGIIIGNGIIVTVCDAENEFLENLPKRDINLKFHSRFALEILTTIADHYNRNLRLLNKSRIRIEKELKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLIIENNQAIETTELHQRILESITTSYASLLSNDMNTIMKTLTLFTVLLTLPTLVFSFFGMNVPLPIDDHSYISWIIVVGISLILVVIVSIFLWRKQKL
>LS483308.1|SQE64930.1|2391519_2392143_+|Transcriptional-regulator,-TetR-family
MKEDRRIRKTKSSIKQAFTKLLQEKDLEKITIRDITTRADINRGTFYLHYEDKYMLLADMEDEYISELTTYTQFDLLRGSSIEDIANTFVNNILKNIFQHIHDNLEFYHTILQLERTSQLELKINEHIKNNMQRYISINHSIGGIPEMYFYSYVSGATISIIKYWVMDKQPISVDELAKHVHNIIFNGPLRIMAENRLHKSNLDSLT
>LS483308.1|SQE64929.1|2390081_2391359_-|Phage-infection-protein
MNIFKNKLLWIAPIATMIILVIFSLAFYPAYNPKPKDLPIGILNEDKGTTIQDKNINIGKKLEDKLLDSDSNKIKWVKVDSEKDLEKDLKDQKIFGVAIIDKDFSKDAMSKTQKVVMDSKKEEMQQKVASGEIPPQVVQQMKQKMGNQQVEVKQAKFKTIVSEGSSLQGSQIASAVLTGMGDNINAQITKQSLETLTSQNVKVNAADINGLTNPVKVDNEKLNKVKDHQAGGNAPFLMFMPIWIGSIVTSILLFFAFRTSNNIVVQHRIIASIGQMIFAVVAAFAGSFVYIYFMQGVQRFDFDHPNRIAIFVAFAILGFVGLILGVMVWLGMKSVPIFFILMFFSMQLVTLPKQMLPESYQKYVYDWNPFTHYATSVRELLYLNHHIELNSTMWMFIGFMIFGAVSSLVSAIVRKHSTKRTEVPS
>LS483308.1|SQE64928.1|2389443_2389875_-|membrane-protein
MRRLLYSFLFYMIIGLFSGFFYRELTKAYDFTGTTQLSLVHTHTLILGMFMFLILLPLEKLFKLSSYYLFNWFFYVYNIGVIVTIGMMVTKGFFQVTGKSYSPEAFAGFAGIGHTGMLAGLLLLFFLLRQAILKEPRDESFKK
>LS483308.1|SQE64927.1|2388177_2389212_-|Thioredoxin-disulfide-reductase
MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYPEKIIWDIGGIAPKPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVIIAIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKDVLISGGGNTALDWAHDIAKIAKRVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDTHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTTTSIPGIYACGDIVYHDAKSHLIASAFSDGANAANLAKTYIQPDANAEGYVSSHHEVFKEANKTIVNKHLY
>LS483308.1|SQE64937.1|2400215_2401493_-|Proton/glutamate-symport-protein;-Sodium/glutamate-symport-protein
MALFKRKISLPMQVVIALVLGVVVGLLLYGQENVANYIKPFGDVFLNLIKMIVIPVVFCSLALSISNVGESKTVGRYGWKTILYFEIITTIAIGLGIIFGNLFKPGAGLDPTKLPKGDISKYQSTAHAAEQSTYGNHFIDTIVHIIPTNFFEALNKGELLPIIFFAVFFGLGLAAVGKKAEPVKEFLSGSLEAVFWMINKILKLAPLGVFAFICTTIITFGASALLPLLKLVLVVVFAMVFFVFAILGLVAWMCGINIMNIIRILKSELLLAFSTSSSEAVLPVMMKKMENFGSPKEITSFVIPIGYTFNLDGSALYQSIAALFVAQMYGMHLTLSEQIVLMLTLMITSKGMAAVPGTSIVVLLTTLGAMGLPAQGLALIIGVDRILDMVRTCVNVIGNALSTIVIAKWENVYDKAKGQEYLKSI
>LS483308.1|SQE64938.1|2401674_2402040_-|exported-protein
MKKKKNAIKVIIILFISLIVAVAFFFGLKTYQGHKNIQLIDSYLEEKNLKDKIKSEKTEYSAKKGLFYKEVTFKDEPGVTYVVQPISTNKGLFVEGFDTETKKSLKTAKHKYFNQNYKPSK
>LS483308.1|SQE64939.1|2402437_2402956_+|MarR-family-transcriptional-regulator
MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDKKITPYHKVMGRSMHRYVYSLSLLLV
>LS483308.1|SQE64940.1|2403106_2403529_+|small-heat-shock-protein
MNFNQFENQNFFNGNPSDTFKDLGKQVFNYFSTPSFVTNIYETDELYYLEAELAGVNKEDISIDFNNNTLTIQATRSAKHKSEQLILDERNFESLMRQFDFEAVDKQHITASFENGLLTITLPKIKPSNESTSSTSIPIS
>LS483308.1|SQE64941.1|2403635_2404805_-|nitrite-extrusion-protein
MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMASGFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQTTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGAFVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDFVVMIIGAIILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFLNEAGSANGIVSMMGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKNG
>LS483308.1|SQE64942.1|2405232_2405886_-|Two-component-response-regulator
MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
>LS483308.1|SQE64943.1|2405908_2406943_-|Two-component-sensor-histidine-kinase
MINEDSIQLDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAKDILSEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDSVIQEMLNVDVQLRLLKYQEDTTKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIYTSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAELVSGSVNIETKIGEGTNVTLNIPI
>LS483308.1|SQE64944.1|2406966_2407419_-|nreA-protein
MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIILRKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVLLFGQRDGRPLPKIFDNDDIQRKFGIFNDDK
>LS483308.1|SQE64945.1|2407438_2408116_-|Respiratory-nitrate-reductase-gamma-chain
MLNQFLWVIFPYLCLVVFVAGHIARYRYDKFSWTAKSSELIERKRLMWGSLLFHLGIIPVFFGHVVGLLIPKSWMDAAGVSEHLYHIGAVYIGSIFGIITLVGMFLLTARRVTTKSIRRLSSASDIFVNFLLLLIVFMGCYATLVTNVQHPDFNYRTSLSIWFRQLFMLKPDASLMSGVPIAFKIHILLGFTIMACWPFTRLVHVWSVPLTYINRRYIIYRKNKV
>LS483308.1|SQE64946.1|2408108_2408684_-|respiratory-nitrate-reductase-subunit-delta
MINFDNFKKYQESFGYMAQQLCFPEKLTFHPKTFEETISTDHPAYEDLVAFRNVMMTFSLSEIKAIYTDTFDFTKKAPLYMTYNKFDTQKERGQMLAKLKVLYEMFGLEMVDNELSDYLPLMLQFLQVAEWRNDPRAEENIQLIIMIIEDGTYVMANVLGEDNNPYAYVIQALRKTLKLCLTSPKGVKHHA

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Crispr_ID: LS483308_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483308_5

2433106-2433203

Orphan

Consensus_repeat	Method
TTTCTACGAATTTTATGAGCTAGAAAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483308_5

>merge|LS483308|5|2433106-2433203|CRISPRCasFinder
TTTCTACGAATTTTATGAGCTAGAAAGGCTTATGCATTAGTAGCGAAGCTAACTAATGCGTTCCTTTATTTTCTGCGAATTTTATGAGCTAGAAAGGC

>LS483308|5|5|2433106-2433203|CRISPRCasFinder
TTTCTACGAATTTTATGAGCTAGAAAGGC	TTATGCATTAGTAGCGAAGCTAACTAATGCGTTCCTTTAT
TTTCTGCGAATTTTATGAGCTAGAAAGGC

Protein	Signature genes	Signature genes Name	Protein_function
LS483308.1\|SQE64975.1\|2439587_2440280_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
LS483308.1\|SQE64965.1\|2428315_2429095_-\|Cysteine-ABC-transporter,-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270429
LS483308.1\|SQE64973.1\|2438080_2439058_+\|Gamma-hemolysin-component-B	unknown	unknown	gnl\|CDD\|273388
LS483308.1\|SQE64966.1\|2429215_2430655_-\|transport-system-protein	unknown	unknown	gnl\|CDD\|129794
LS483308.1\|SQE64971.1\|2435599_2436565_+\|gamma-hemolysin-component-A-protein	unknown	unknown	gnl\|CDD\|369625
LS483308.1\|SQE64961.1\|2424923_2425286_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|291399
LS483308.1\|SQE64979.1\|2443728_2444415_-\|dethiobiotin-synthetase	unknown	unknown	gnl\|CDD\|223210
LS483308.1\|SQE64967.1\|2430828_2430933_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483308.1\|SQE64960.1\|2424305_2424905_-\|Protein-disulfide-isomerase,-DsbA-like-protein	unknown	unknown	gnl\|CDD\|224565
LS483308.1\|SQE64969.1\|2432099_2432966_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
LS483308.1\|SQE64974.1\|2439109_2439577_-\|BioX-protein	unknown	unknown	gnl\|CDD\|377623
LS483308.1\|SQE64964.1\|2427615_2428344_-\|cystine-transport-system-permease-protein	unknown	unknown	gnl\|CDD\|223836
LS483308.1\|SQE64978.1\|2442392_2443751_-\|Adenosylmethionine-8-amino-7-oxononanoate-aminotransferase	unknown	unknown	gnl\|CDD\|273109
LS483308.1\|SQE64977.1\|2441383_2442391_-\|Biotin-synthase	unknown	unknown	gnl\|CDD\|235755
LS483308.1\|SQE64968.1\|2431086_2431773_-\|Phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518
LS483308.1\|SQE64970.1\|2433786_2435100_+\|IgG-binding-protein-SBI	unknown	unknown	gnl\|CDD\|288473
LS483308.1\|SQE64976.1\|2440290_2441406_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|223234
LS483308.1\|SQE64972.1\|2437131_2438079_+\|Leukocidin-S-subunit	unknown	unknown	gnl\|CDD\|369625
LS483308.1\|SQE64963.1\|2426887_2427619_-\|amino-acid-ABC-transporter,-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
LS483308.1\|SQE64962.1\|2425540_2426791_+\|FmhA-protein-of-FemAB-family	unknown	unknown	gnl\|CDD\|367067

Protein	Function_ID	Function_description	E-value
LS483308.1\|SQE64975.1\|2439587_2440280_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	2.9803e-130
LS483308.1\|SQE64965.1\|2428315_2429095_-\|Cysteine-ABC-transporter,-substrate-binding-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.20682e-100
LS483308.1\|SQE64973.1\|2438080_2439058_+\|Gamma-hemolysin-component-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
LS483308.1\|SQE64966.1\|2429215_2430655_-\|transport-system-protein	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.41176e-92
LS483308.1\|SQE64971.1\|2435599_2436565_+\|gamma-hemolysin-component-A-protein	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	6.13066e-97
LS483308.1\|SQE64961.1\|2424923_2425286_-\|Uncharacterised-protein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	3.11961e-31
LS483308.1\|SQE64979.1\|2443728_2444415_-\|dethiobiotin-synthetase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.45777e-70
LS483308.1\|SQE64960.1\|2424305_2424905_-\|Protein-disulfide-isomerase,-DsbA-like-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	1.74649e-30
LS483308.1\|SQE64969.1\|2432099_2432966_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.54055e-90
LS483308.1\|SQE64974.1\|2439109_2439577_-\|BioX-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.000705213
LS483308.1\|SQE64964.1\|2427615_2428344_-\|cystine-transport-system-permease-protein	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.24685e-78
LS483308.1\|SQE64978.1\|2442392_2443751_-\|Adenosylmethionine-8-amino-7-oxononanoate-aminotransferase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
LS483308.1\|SQE64977.1\|2441383_2442391_-\|Biotin-synthase	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
LS483308.1\|SQE64968.1\|2431086_2431773_-\|Phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167
LS483308.1\|SQE64970.1\|2433786_2435100_+\|IgG-binding-protein-SBI	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	3.25122e-27
LS483308.1\|SQE64976.1\|2440290_2441406_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	2.68826e-138
LS483308.1\|SQE64972.1\|2437131_2438079_+\|Leukocidin-S-subunit	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	7.97441e-93
LS483308.1\|SQE64963.1\|2426887_2427619_-\|amino-acid-ABC-transporter,-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.20826e-144
LS483308.1\|SQE64962.1\|2425540_2426791_+\|FmhA-protein-of-FemAB-family	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0

>LS483308.1|SQE64969.1|2432099_2432966_-|cation-diffusion-facilitator-family-transporter
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNAITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>LS483308.1|SQE64968.1|2431086_2431773_-|Phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>LS483308.1|SQE64967.1|2430828_2430933_+|Uncharacterised-protein
MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK
>LS483308.1|SQE64966.1|2429215_2430655_-|transport-system-protein
MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGVVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIDMMNQIKVDTMLHGYHAGFLFALLITVVSFFCSFMLQGKKKEVDSRQ
>LS483308.1|SQE64965.1|2428315_2429095_-|Cysteine-ABC-transporter,-substrate-binding-protein
MKRLLFVMIAFVFILAACGNNSSKDKEASKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSRSAFAFSKKADDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>LS483308.1|SQE64964.1|2427615_2428344_-|cystine-transport-system-permease-protein
MVKMFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>LS483308.1|SQE64963.1|2426887_2427619_-|amino-acid-ABC-transporter,-ATP-binding-protein
MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEARGKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEMFNRPKTEELRRFLNVINEE
>LS483308.1|SQE64962.1|2425540_2426791_+|FmhA-protein-of-FemAB-family
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
>LS483308.1|SQE64961.1|2424923_2425286_-|Uncharacterised-protein
MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDSRRYYQQHDADYHEENMTN
>LS483308.1|SQE64960.1|2424305_2424905_-|Protein-disulfide-isomerase,-DsbA-like-protein
MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKCPYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>LS483308.1|SQE64970.1|2433786_2435100_+|IgG-binding-protein-SBI
MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKETPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNVKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNTYYKYKGAIDKAVLTLLGDGSKSYIQPLKVDDKNGYLAKSYAQVRNYVTESINTGKVLYTFYQNPTLVKTAIKAQETASSIKNTITGLFNSFWK
>LS483308.1|SQE64971.1|2435599_2436565_+|gamma-hemolysin-component-A-protein
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>LS483308.1|SQE64972.1|2437131_2438079_+|Leukocidin-S-subunit
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN
>LS483308.1|SQE64973.1|2438080_2439058_+|Gamma-hemolysin-component-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>LS483308.1|SQE64974.1|2439109_2439577_-|BioX-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>LS483308.1|SQE64975.1|2439587_2440280_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDNRIDLNHYISFLESTPKQVVYETV
>LS483308.1|SQE64976.1|2440290_2441406_-|8-amino-7-oxononanoate-synthase
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEVIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>LS483308.1|SQE64977.1|2441383_2442391_-|Biotin-synthase
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>LS483308.1|SQE64978.1|2442392_2443751_-|Adenosylmethionine-8-amino-7-oxononanoate-aminotransferase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>LS483308.1|SQE64979.1|2443728_2444415_-|dethiobiotin-synthetase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483308_4	4.1\|2400123\|28\|LS483308\|CRISPRCasFinder	2400123-2400150	28	NZ_CP017941	Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence	286024-286051	7	0.75
LS483308_3	3.1\|2176770\|34\|LS483308\|CRISPRCasFinder	2176770-2176803	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
LS483308_3	3.1\|2176770\|34\|LS483308\|CRISPRCasFinder	2176770-2176803	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 4.1|2400123|28|LS483308|CRISPRCasFinder matches to NZ_CP017941 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.75

cacttcgcttcggttcgcctgcgctttt	CRISPR spacer
tgtttcgcttcggatcgcctgagcttcc	Protospacer
...********** ******* ****..

2. spacer 3.1|2176770|34|LS483308|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

3. spacer 3.1|2176770|34|LS483308|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

723961 : 731781

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE63372.1\|723961_725017_-	Sensor histidine protein kinase SaeS (exoprotein expression protein S)	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
SQE63373.1\|725016_725703_-	Response regulator SaeR	NA	NA	NA	NA
SQE63374.1\|725677_726151_-	DoxX family protein	NA	NA	NA	NA
SQE63375.1\|726492_726933_-	lipoprotein	NA	NA	NA	NA
SQE63376.1\|727212_727797_-	Uncharacterised protein	NA	NA	NA	NA
SQE63377.1\|727895_728609_-	Queuosine Biosynthesis QueE Radical SAM	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
SQE63378.1\|728612_729032_-	6-pyruvoyl-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
SQE63379.1\|729033_729702_-	Queuosine Biosynthesis QueC ATPase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
SQE63380.1\|730052_730646_+	Para-aminobenzoate synthase, amidotransferase component PabAb	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
SQE63381.1\|730629_731781_+	Para-aminobenzoate synthetase component I	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_2

743751 : 758149

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE63390.1\|743751_744810_+	histidinol-phosphate aminotransferase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
SQE63391.1\|744683_744965_-	Protein of uncharacterised function (DUF3125)	NA	NA	NA	NA
SQE63392.1\|745104_745647_+	5'-3'-deoxyribonucleotidase, putative	NA	NA	NA	NA
SQE63393.1\|746326_747244_-	Transcription regulator (contains diacylglycerol kinase catalytic domain)	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
SQE63394.1\|747513_749019_-	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
SQE63395.1\|749359_749860_-	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
SQE63396.1\|749879_750746_-	Integral membrane domain protein	NA	NA	NA	NA
SQE63397.1\|751546_751945_+	Nrdi	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
SQE63398.1\|751907_754013_+	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
SQE63399.1\|754130_755102_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
SQE63400.1\|755434_756451_+	FatD	A0A2H4IY97	uncultured_Caudovirales_phage	2.2e-138	77.8
SQE63401.1\|756434_757391_+	Iron compound ABC uptake transporter permease protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
SQE63402.1\|757387_758149_+	Iron compound ABC uptake transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

999981 : 1008454

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE63628.1\|999981_1000464_+	AIR carboxylase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
SQE63629.1\|1000450_1001575_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
SQE63630.1\|1001578_1002283_+	Phosphoribosylaminoimidazole-succinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
SQE63631.1\|1002282_1002546_+	Phosphoribosylformylglycinamidine synthase, PurS subunit	NA	NA	NA	NA
SQE63632.1\|1002547_1003219_+	Phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
SQE63633.1\|1003211_1005401_+	Phosphoribosylformylglycinamidine synthase, synthetase subunit	A6N228	Microbacterium_phage	7.9e-141	39.7
SQE63634.1\|1005379_1006864_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
SQE63635.1\|1006856_1007885_+	Phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
SQE63636.1\|1007887_1008454_+	Phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1

DBSCAN-SWA_4

1242526 : 1298767

Staphylococcus_phage(53.19%)

portal,integrase,terminase,tRNA,capsid,holin,tail

attL 1262684:1262721|attR 1297361:1297398

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE63850.1\|1242526_1244071_+\|tRNA	tRNA-i(6)A37 methylthiotransferase	NA	NA	NA	NA
SQE63851.1\|1244071_1244437_+	membrane protein	NA	NA	NA	NA
SQE63852.1\|1244463_1244955_+	Substrate-specific component ThiWthiazole ECF transporter	NA	NA	NA	NA
SQE63853.1\|1245257_1247876_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	8.5e-41	23.7
SQE63854.1\|1247888_1249898_+	DNA mismatch repair protein MutL	A0A1B2LRQ5	Wolbachia_phage	2.8e-60	30.8
SQE63855.1\|1249912_1250446_+	glycerol uptake operon antiterminator regulatory protein	NA	NA	NA	NA
SQE63856.1\|1250920_1251739_+	Glycerol uptake facilitator protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	2.4e-26	35.1
SQE63857.1\|1251867_1253364_+	glycerol kinase	NA	NA	NA	NA
SQE63858.1\|1253521_1255195_+	Glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
SQE63859.1\|1255341_1256259_+	hydrolase	NA	NA	NA	NA
SQE63860.1\|1256276_1257212_+\|tRNA	tRNA delta(2)-isopentenylpyrophosphate transferase	NA	NA	NA	NA
SQE63861.1\|1257226_1257460_+	RNA-binding protein Hfq	NA	NA	NA	NA
SQE63862.1\|1257681_1258158_-	Glutathione peroxidase family protein	Q70H87	Fowlpox_virus	1.2e-22	38.0
SQE63863.1\|1258269_1259508_+	GTP-binding protein	NA	NA	NA	NA
SQE63864.1\|1259526_1260765_+	aluminum resistance protein, putative	NA	NA	NA	NA
SQE63865.1\|1261008_1261377_+	FemC, factor involved in methicillin resistance / Glutamine synthetase repressor	NA	NA	NA	NA
SQE63866.1\|1261395_1262736_+	glutamine synthetase	NA	NA	NA	NA
1262684:1262721	attL	NA	NA	NA	NA
SQE63867.1\|1262875_1264003_-\|integrase	integrase family protein	A0A0C5AN64	Paenibacillus_phage	1.1e-32	31.2
SQE63868.1\|1264055_1264751_-	host cell surface-exposed lipofamily protein	A0A2H4J5B8	uncultured_Caudovirales_phage	3.6e-07	43.9
SQE63869.1\|1264762_1265146_-	Uncharacterised protein	NA	NA	NA	NA
SQE63870.1\|1265292_1265661_-	helix-turn-helix family protein	S4SVC5	Staphylococcus_phage	2.4e-18	43.4
SQE63871.1\|1265812_1266022_+	helix-turn-helix family protein	A7TWF1	Staphylococcus_phage	4.1e-15	58.7
SQE63872.1\|1266065_1266341_+	Uncharacterised protein	NA	NA	NA	NA
SQE63873.1\|1266345_1266480_+	Uncharacterised protein	NA	NA	NA	NA
SQE63874.1\|1266510_1266609_+	Uncharacterised protein	NA	NA	NA	NA
SQE63875.1\|1266605_1266776_+	Uncharacterised protein	Q4ZDZ8	Staphylococcus_virus	4.1e-21	87.5
SQE63876.1\|1266764_1266971_-	Uncharacterised protein	A1BTY8	Staphylococcus_virus	3.6e-24	73.5
SQE63877.1\|1267031_1267715_+	prophage, antirepressor, putative	A9CR56	Staphylococcus_phage	7.2e-109	86.5
SQE63878.1\|1267813_1267975_+	phage protein	R4IH12	Staphylococcus_phage	8.6e-13	69.8
SQE63879.1\|1268061_1268379_+	phage protein	W5RAK4	Staphylococcus_phage	1.6e-39	80.6
SQE63880.1\|1268344_1268635_+	phage protein	A0A1P8L6F4	Staphylococcus_phage	9.4e-18	52.4
SQE63881.1\|1268639_1269176_+	glycosyl hydrolases 17 family protein	A0A0H3U480	Staphylococcus_phage	1.7e-76	82.5
SQE63882.1\|1269176_1269956_+	bacterial dnaA family protein	A0A1W6JPW0	Staphylococcus_phage	2.3e-127	88.0
SQE63883.1\|1269982_1270531_+	Single stranded DNA-binding protein,phage-associated	A7TWM8	Staphylococcus_phage	2.9e-92	93.5
SQE63884.1\|1270544_1271462_+	dnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	8.6e-49	51.1
SQE63885.1\|1271462_1271753_+	PVL orf 51-like protein	A0A223LIA9	Staphylococcus_phage	2.7e-17	56.8
SQE63886.1\|1271767_1271926_+	phage protein	A0A0E3T9L7	Staphylococcus_phage	4.6e-19	94.2
SQE63887.1\|1271931_1272243_+	Uncharacterised protein	NA	NA	NA	NA
SQE63888.1\|1272235_1272766_+	mazG nucleotide pyrophosphohydrolase domain protein	A0A1P8VVP1	Streptococcus_phage	1.4e-22	38.5
SQE63889.1\|1272799_1273264_+	Uncharacterised protein	C9E2P0	Enterococcus_phage	1.9e-20	43.0
SQE63890.1\|1273264_1273498_+	Uncharacterised protein	NA	NA	NA	NA
SQE63891.1\|1273540_1274029_+	sigma-70, region 4 family protein	R9TMH4	Paenibacillus_phage	5.1e-08	27.7
SQE63892.1\|1274181_1274610_+	homeo-like domain protein	A1EAE0	Streptococcus_phage	1.1e-25	45.1
SQE63893.1\|1274596_1275871_+\|terminase	phage terminase, large subunit, PBSX family	Q4ZE37	Staphylococcus_virus	1.9e-195	76.4
SQE63894.1\|1275883_1277332_+\|portal	phage portal protein, SPP1 family	Q4ZE36	Staphylococcus_virus	1.4e-194	69.2
SQE63895.1\|1277321_1278671_+	phage Mu protein F like protein (pseudogene)	A0A1J0MF61	Staphylococcus_phage	1.7e-141	57.6
SQE63896.1\|1278672_1278870_+	Uncharacterised protein	NA	NA	NA	NA
SQE63897.1\|1279028_1279607_+	Phage protein	Q4ZE34	Staphylococcus_virus	1.9e-09	50.8
SQE63898.1\|1279625_1280525_+\|capsid	phage major capsid protein Fam0118	Q4ZE33	Staphylococcus_virus	2.0e-98	61.1
SQE63899.1\|1280602_1281076_+\|tail	phage phiSLT minor tail protein	A0A1X9I9L0	Staphylococcus_phage	1.7e-08	26.5
SQE63900.1\|1281091_1281418_+	phi 11 orf36	Q4ZE31	Staphylococcus_virus	1.1e-25	55.5
SQE63901.1\|1281417_1281723_+	phage protein	Q4ZE30	Staphylococcus_virus	6.4e-17	40.6
SQE63902.1\|1281723_1282074_+	phage protein	H9A0N6	Staphylococcus_phage	9.3e-36	60.0
SQE63903.1\|1282083_1282479_+	phi 11 orf38	H9A0N7	Staphylococcus_phage	1.9e-21	42.3
SQE63904.1\|1282490_1283090_+\|tail	phage tail protein	H9A0N8	Staphylococcus_phage	7.4e-17	47.5
SQE63905.1\|1283151_1283496_+	phage protein	A0A1J0MFH0	Staphylococcus_phage	1.0e-34	58.9
SQE63906.1\|1283492_1283900_+	phi 11 orf41	Q4ZE25	Staphylococcus_virus	2.6e-37	72.3
SQE63907.1\|1283911_1287082_+\|tail	phage tail length tape-measure protein	Q4ZE24	Staphylococcus_virus	1.4e-93	57.5
SQE63908.1\|1287096_1288032_+	phi 11 orf43	A0A1J0MF79	Staphylococcus_phage	1.0e-97	55.9
SQE63909.1\|1288040_1289726_+	phage minor structural protein	Q4ZE19	Staphylococcus_virus	3.0e-108	46.5
SQE63910.1\|1289743_1290757_+	phage minor structural protein	A0A1J0MFI8	Staphylococcus_phage	4.2e-97	52.3
SQE63911.1\|1290775_1292173_+	Uncharacterised protein	A0A1J0MFK8	Staphylococcus_phage	2.6e-105	44.7
SQE63912.1\|1292185_1292575_+\|holin	holin	A0A1S6L1J2	Staphylococcus_phage	5.3e-16	38.2
SQE63913.1\|1292639_1293560_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JQL2	Staphylococcus_phage	1.0e-65	50.8
SQE63914.1\|1294447_1295383_+	Abortive infection bacteriophage resistance protein	A0A059NT88	Lactococcus_phage	1.4e-70	44.3
SQE63915.1\|1295833_1296250_+	Uncharacterised protein	NA	NA	NA	NA
SQE63916.1\|1296703_1296907_+	Uncharacterised protein	A0A2H4PQT0	Staphylococcus_phage	4.4e-14	61.8
SQE63917.1\|1296980_1297076_+	Uncharacterised protein	NA	NA	NA	NA
SQE63918.1\|1297426_1298767_+	phage Mu protein F like protein (pseudogene)	A0A1J0MF61	Staphylococcus_phage	1.1e-140	58.9
1297361:1297398	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1572602 : 1580914

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE64151.1\|1572602_1573388_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.3e-18	27.9
SQE64152.1\|1573513_1574404_-	endonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
SQE64153.1\|1574413_1575760_-	ATP-dependent RNA helicase YqfR	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
SQE64154.1\|1575873_1576974_-	NIF3 protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
SQE64155.1\|1576976_1577654_-\|tRNA	Putative tRNA-m1A22 methylase	NA	NA	NA	NA
SQE64156.1\|1577784_1578891_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
SQE64157.1\|1579114_1580914_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.0e-53	36.3

DBSCAN-SWA_6

1648747 : 1657790

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE64226.1\|1648747_1649266_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
SQE64227.1\|1649287_1651561_-	Single-stranded-DNA-specific exonuclease recJ	A7KV88	Bacillus_phage	2.4e-63	29.1
SQE64228.1\|1651763_1654043_-	Protein-export membrane protein secD / Protein-export membrane protein secF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
SQE64229.1\|1654317_1654578_-	Preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
SQE64230.1\|1654596_1655736_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
SQE64231.1\|1655758_1656784_-\|tRNA	S-adenosylmethionine--tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
SQE64232.1\|1656785_1657790_-	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_7

1788838 : 1853311

Staphylococcus_phage(95.83%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE64340.1\|1788838_1795399_-	LPXTG-motif cell wall anchor domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	3.5e-309	98.5
SQE64341.1\|1795724_1796036_-	Rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
SQE64342.1\|1796057_1798475_-\|tRNA	Leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
SQE64343.1\|1798762_1799944_-	Multidrug resistance protein	A0A2H4PQR6	Staphylococcus_phage	5.1e-211	96.4
SQE64344.1\|1800053_1801007_+	Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
SQE64345.1\|1801003_1801567_+	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	4.1e-102	98.9
SQE64346.1\|1801686_1802088_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
SQE64347.1\|1802659_1803487_-	Lysophospholipase; Monoglyceride lipase; putative	NA	NA	NA	NA
SQE64348.1\|1803720_1804722_+	Proline dehydrogenase (Proline oxidase)	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
SQE64349.1\|1804843_1805308_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
SQE64350.1\|1805320_1806502_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.5e-226	99.5
SQE64351.1\|1806512_1807145_-	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	3.4e-113	100.0
SQE64352.1\|1807151_1808195_-	5-amino-6-(5-phosphoribosylamino)uracil reductase	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.4
SQE64353.1\|1808675_1810178_-	pyridine nucleotide-disulfide oxidoreductase family protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
SQE64354.1\|1810700_1811015_+	arsenical resistance operon repressor 2	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
SQE64355.1\|1811014_1812307_+	arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
SQE64356.1\|1812393_1813248_-	peptidoglycan endo-beta-N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
SQE64357.1\|1813523_1813748_-	putative staphylococcal protein	NA	NA	NA	NA
SQE64358.1\|1813946_1814417_+	RNA polymerase sigma factor sigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
SQE64359.1\|1814529_1814973_+	comK family protein	NA	NA	NA	NA
SQE64360.1\|1814959_1815403_-	putative staphylococcal protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
SQE64361.1\|1815698_1816334_+\|protease	CAAX amino terminal protease	NA	NA	NA	NA
SQE64362.1\|1816773_1817487_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
SQE64363.1\|1817746_1818049_+	membrane protein	NA	NA	NA	NA
SQE64364.1\|1818304_1818670_+	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
SQE64365.1\|1818666_1819020_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
SQE64366.1\|1819402_1820236_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
SQE64367.1\|1820447_1821356_-	Uncharacterised protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
SQE64368.1\|1821480_1822674_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
SQE64369.1\|1823045_1824638_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
SQE64370.1\|1824890_1825661_-	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	2.3e-143	99.6
SQE64371.1\|1825641_1826121_-	phosphohydrolase	A0A2H4PQM4	Staphylococcus_phage	1.7e-85	100.0
SQE64372.1\|1826180_1826438_+	Putative cytosolic protein	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
SQE64373.1\|1826434_1827436_-	O-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.1e-188	98.8
SQE64374.1\|1827440_1828919_-	O-succinylbenzoic acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.6e-283	98.0
SQE64375.1\|1829077_1829560_-	putative lipoprotein	A0A2H4PQN7	Staphylococcus_phage	7.2e-79	98.6
SQE64376.1\|1829871_1830486_+	endonuclease	A0A2H4PQM8	Staphylococcus_phage	1.9e-47	98.0
SQE64377.1\|1830566_1831562_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	8.1e-69	93.5
SQE64378.1\|1831637_1832264_+	lipoprotein	A0A2H4PQM7	Staphylococcus_phage	2.9e-96	96.6
SQE64379.1\|1832304_1832646_+	Uncharacterised protein	A0A2H4PQN6	Staphylococcus_phage	1.0e-55	96.5
SQE64380.1\|1832746_1833319_+	Uncharacterised protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
SQE64381.1\|1833516_1834074_-	Domain of uncharacterised function (DUF955)	A0A2H4PQN8	Staphylococcus_phage	3.5e-77	96.2
SQE64382.1\|1834444_1834621_-	Uncharacterised protein	NA	NA	NA	NA
SQE64383.1\|1834631_1835153_-	Uncharacterised protein	NA	NA	NA	NA
SQE64384.1\|1835699_1836146_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
SQE64385.1\|1837263_1837638_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
SQE64386.1\|1837659_1838007_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
SQE64387.1\|1838216_1838660_-	putative protein with DUF1433	NA	NA	NA	NA
SQE64388.1\|1839307_1840426_-	type I restriction-modification system, S subunit	A0A2H4PQP5	Staphylococcus_phage	7.6e-39	35.1
SQE64389.1\|1840418_1841975_-	Type I restriction enzyme EcoprrI M protein	A0A2H4PQP4	Staphylococcus_phage	2.6e-287	99.0
SQE64390.1\|1842337_1843057_-\|protease	Serine protease splD	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
SQE64391.1\|1843208_1843925_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	2.4e-131	99.2
SQE64392.1\|1844082_1844802_-\|protease	Serine protease splD	A0A2H4PQP9	Staphylococcus_phage	1.3e-129	98.7
SQE64393.1\|1844922_1845642_-\|protease	Serine protease splC	A0A2H4PQP7	Staphylococcus_phage	5.1e-129	98.3
SQE64394.1\|1845699_1846422_-\|protease	Serine protease splB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
SQE64395.1\|1846578_1847238_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.0e-111	94.5
SQE64396.1\|1848216_1848798_+	beta-lactamase	A0A2H4PQH6	Staphylococcus_phage	2.6e-51	62.7
SQE64397.1\|1849278_1849551_-	truncated BsaG protein	A0A2H4PQH0	Staphylococcus_phage	4.8e-32	82.4
SQE64398.1\|1849752_1850226_+	Uncharacterised protein	NA	NA	NA	NA
SQE64399.1\|1850230_1851022_+	Domain of uncharacterised function DUF1828	NA	NA	NA	NA
SQE64400.1\|1851390_1852374_-	Leukotoxin LukD	A0A2H4PQH7	Staphylococcus_phage	1.5e-184	98.8
SQE64401.1\|1852375_1853311_-	Leukocidin S subunit lukE	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0

DBSCAN-SWA_8

1942343 : 2029381

110

Staphylococcus_phage(83.75%)

protease,terminase,tRNA,capsid,holin,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE64479.1\|1942343_1942646_-\|tRNA	Aspartyl-tRNA(Asn) amidotransferase subunit C; Glutamyl-tRNA(Gln) amidotransferase subunit C	NA	NA	NA	NA
SQE64480.1\|1943012_1944551_+	Sodium/proline symporter	NA	NA	NA	NA
SQE64481.1\|1944639_1945839_-	Lipoprotein (pheromone precursor)	NA	NA	NA	NA
SQE64482.1\|1945851_1947855_-	DNA ligase	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
SQE64483.1\|1947858_1950051_-	ATP-dependent DNA helicase UvrD/PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
SQE64484.1\|1950047_1950740_-	geranylgeranylglyceryl diphosphate synthase	NA	NA	NA	NA
SQE64485.1\|1950911_1951214_-	His repressor	NA	NA	NA	NA
SQE64486.1\|1951322_1952618_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
SQE64487.1\|1953478_1954645_+	Staphopain A precursor	NA	NA	NA	NA
SQE64488.1\|1954675_1955002_+\|protease	putative cysteine protease inhibitor (Staphostatin A)	NA	NA	NA	NA
SQE64489.1\|1955293_1955467_-	Uncharacterised protein	NA	NA	NA	NA
SQE64490.1\|1955447_1956050_-	Uncharacterized protein conserved in bacteria (DUF2179)	NA	NA	NA	NA
SQE64491.1\|1956320_1957142_-	NH(3)-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
SQE64492.1\|1957134_1958604_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.5e-108	45.1
SQE64493.1\|1958787_1959864_+	nitric-oxide synthase	NA	NA	NA	NA
SQE64494.1\|1959883_1960678_+	ACT domain protein	NA	NA	NA	NA
SQE64495.1\|1960867_1962430_-	sodium-dependent dicarboxylate transporter sdcS	NA	NA	NA	NA
SQE64496.1\|1962634_1963732_-	cell wall surface anchor family protein	U5PWM6	Bacillus_phage	3.3e-47	34.6
SQE64497.1\|1964103_1964664_+	Nicotinamidase	G3MA16	Bacillus_virus	2.0e-32	41.2
SQE64498.1\|1964716_1965646_+	inorganic pyrophosphatase	NA	NA	NA	NA
SQE64499.1\|1966063_1967443_+	Aldehyde dehydrogenase	NA	NA	NA	NA
SQE64500.1\|1967562_1968591_-	6-phosphogluconolactonase	NA	NA	NA	NA
SQE64501.1\|1968860_1969262_+	yolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
SQE64502.1\|1969834_1970008_-	exported protein	NA	NA	NA	NA
SQE64503.1\|1970386_1971499_+	choloylglycine hydrolase	NA	NA	NA	NA
SQE64504.1\|1971555_1972398_-	exported protein	NA	NA	NA	NA
SQE64505.1\|1972394_1972952_-	Predicted membrane protein	NA	NA	NA	NA
SQE64506.1\|1973012_1973537_-	membrane protein	NA	NA	NA	NA
SQE64507.1\|1973657_1974221_+	Thioredoxin	NA	NA	NA	NA
SQE64508.1\|1974286_1975027_-	ABC-2 transporter family protein	NA	NA	NA	NA
SQE64509.1\|1975026_1975899_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
SQE64510.1\|1975895_1976576_-	membrane protein	NA	NA	NA	NA
SQE64511.1\|1976576_1977473_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
SQE64512.1\|1977469_1977850_-	GntR family transcriptional regulator	NA	NA	NA	NA
SQE64513.1\|1978108_1978285_-	membrane protein	NA	NA	NA	NA
SQE64514.1\|1978825_1980112_+	Aspartate aminotransferase	NA	NA	NA	NA
SQE64515.1\|1980435_1980726_-	truncated map-w protein; extracellular adherence protein of broad specificity Eap/Map	NA	NA	NA	NA
SQE64516.1\|1980736_1982485_-	Outer membrane protein	NA	NA	NA	NA
SQE64517.1\|1982870_1983071_+	beta-hemolysin	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0
SQE64518.1\|1984245_1984596_-	Involved in expression of fibrinogen binding protein, phage associated	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
SQE64519.1\|1985107_1985404_-	amidase	A0A1P8L6B4	Staphylococcus_phage	1.6e-49	95.9
SQE64520.1\|1986093_1986585_-	Staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
SQE64521.1\|1986775_1987531_-	Autolysin	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
SQE64522.1\|1987542_1987797_-\|holin	Phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
SQE64523.1\|1988387_1989170_-	Enterotoxin P, phage associated	A0A075M4C7	Staphylococcus_phage	1.6e-149	99.6
SQE64524.1\|1989278_1989455_-	Uncharacterised protein	NA	NA	NA	NA
SQE64525.1\|1989581_1989956_-	phage protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
SQE64526.1\|1990011_1990299_-	phi PVL ORF 22-like protein	A0A075LZJ6	Staphylococcus_phage	5.8e-44	100.0
SQE64527.1\|1990345_1990498_-	phage protein	D2JLG0	Staphylococcus_phage	1.2e-19	98.0
SQE64528.1\|1990487_1994273_-	phage minor structural protein	Q6R866	Staphylococcus_virus	0.0e+00	98.7
SQE64529.1\|1994288_1995773_-	bacteriophage protein	A0A068A242	Staphylococcus_phage	1.5e-297	100.0
SQE64530.1\|1995769_2000284_-\|tail	bacteriophage tail tape measure protein, TP901 family	A0A075M036	Staphylococcus_phage	0.0e+00	91.2
SQE64531.1\|2000340_2000478_-	phage protein	A0A068A227	Staphylococcus_phage	3.4e-18	100.0
SQE64532.1\|2000528_2000879_-	phage protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
SQE64533.1\|2001194_2001839_-\|tail	phage major tail protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
SQE64534.1\|2001839_2002247_-	putative bacteriophage protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
SQE64535.1\|2002243_2002648_-	bacteriophage protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
SQE64536.1\|2002644_2003007_-\|head,tail	phage head-tail adaptor	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
SQE64537.1\|2002990_2003275_-	Gp6 protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
SQE64538.1\|2003264_2003549_-\|terminase	phage terminase small subunit	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
SQE64539.1\|2003568_2004714_-\|capsid	Phage major capsid protein	G4KNQ3	Staphylococcus_phage	2.8e-214	99.7
SQE64540.1\|2004737_2005475_-	ATP-dependent endopeptidase clp proteolytic subunit	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
SQE64541.1\|2005458_2006646_-	Portal protein, phage associated	G4KNQ1	Staphylococcus_phage	4.6e-220	100.0
SQE64542.1\|2006661_2008323_-\|terminase	Phage terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	98.4
SQE64543.1\|2008319_2008664_-	phage protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
SQE64544.1\|2008793_2009090_-	phage-associated homing endonuclease	A0EWY8	Staphylococcus_phage	1.7e-51	100.0
SQE64545.1\|2009324_2009741_-	phage transcriptional regulator	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
SQE64546.1\|2009768_2009969_-	phage protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
SQE64547.1\|2009968_2010118_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
SQE64548.1\|2010114_2010321_-	phage protein	S4V684	Staphylococcus_phage	2.4e-23	82.4
SQE64549.1\|2010357_2010891_-	dUTPase family protein	U5U798	Staphylococcus_phage	7.4e-93	97.7
SQE64550.1\|2010905_2011067_-	Uncharacterised protein	M9NTB4	Staphylococcus_phage	4.9e-24	100.0
SQE64551.1\|2011067_2011241_-	Uncharacterised protein	A0A2H4PQJ2	Staphylococcus_phage	1.8e-24	100.0
SQE64552.1\|2011230_2011482_-	Phage protein	G4KNP4	Staphylococcus_phage	4.1e-38	96.4
SQE64553.1\|2011474_2011885_-	putative phi PVL-like protein	A0A1X9H0B8	Staphylococcus_phage	7.7e-58	85.3
SQE64554.1\|2011881_2012391_-	Uncharacterised protein	A0A1X9H0D4	Staphylococcus_phage	6.2e-89	96.4
SQE64555.1\|2012387_2012795_-	yopX family protein	I6TG10	Staphylococcus_virus	8.8e-30	53.4
SQE64556.1\|2012791_2013196_-	putative phage PVL protein	A0A2I6PDC0	Staphylococcus_phage	2.2e-44	71.4
SQE64557.1\|2013210_2013453_-	phage conserved Open Reading Frame 51	A0A2I6PF06	Staphylococcus_phage	3.6e-39	96.2
SQE64558.1\|2013458_2013713_-	phage protein	Q6R831	Staphylococcus_virus	1.3e-42	100.0
SQE64559.1\|2013712_2014222_-	phage protein	C8CGZ9	Staphylococcus_phage	5.1e-43	91.7
SQE64560.1\|2014222_2014408_-	Protein of uncharacterised function (DUF3113)	Q4ZA46	Staphylococcus_virus	2.1e-26	98.4
SQE64561.1\|2014412_2014817_-	putative phi ETA-like protein	G4KNP2	Staphylococcus_phage	1.6e-68	100.0
SQE64562.1\|2014826_2015048_-	putative phi ETA-like protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
SQE64563.1\|2015060_2015219_-	Uncharacterised protein	A0A2I6PDX0	Staphylococcus_phage	8.4e-21	94.2
SQE64564.1\|2015215_2016001_-	ORF017	A0A2I6PDV5	Staphylococcus_phage	1.6e-144	99.6
SQE64565.1\|2016013_2016835_-	N-terminal phage replisome organizer	A0A0H3U476	Staphylococcus_phage	1.9e-124	98.2
SQE64566.1\|2016806_2017502_-	phage protein	A0A2H4JAQ0	uncultured_Caudovirales_phage	1.7e-129	97.4
SQE64567.1\|2017515_2017944_-	Single-stranded DNA-binding protein, phage associated	B2ZYV4	Staphylococcus_phage	8.6e-60	99.3
SQE64568.1\|2017943_2018567_-	putative phage topoisomerase	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
SQE64569.1\|2018559_2018781_-	phage protein	B2ZYV2	Staphylococcus_phage	3.2e-34	100.0
SQE64570.1\|2018790_2019051_-	Putative cytosolic protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
SQE64571.1\|2019143_2019305_-	phage protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
SQE64572.1\|2019301_2019622_-	Uncharacterized protein conserved in bacteria	A0A2I6PDH6	Staphylococcus_phage	2.5e-56	99.1
SQE64573.1\|2019651_2019870_-	phi PV83 orf 10-like protein	Q4ZBN1	Staphylococcus_phage	3.1e-29	93.1
SQE64574.1\|2019885_2020638_-	antirepressor	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
SQE64575.1\|2020688_2021024_+	Phage protein	M9NS98	Staphylococcus_phage	1.2e-51	98.2
SQE64576.1\|2021041_2021227_-	phage protein	A0A0H3U4C7	Staphylococcus_phage	1.4e-19	100.0
SQE64577.1\|2021242_2021506_-	putative phage transcriptional regulator	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
SQE64578.1\|2021639_2022353_+	CI-like repressor, phage associated	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
SQE64579.1\|2022368_2023301_+	DNA polymerase III subunit alpha	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
SQE64580.1\|2023306_2023648_+	phage protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
SQE64581.1\|2023851_2024019_+	Putative cytosolic protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
SQE64582.1\|2024158_2024698_+	PemK-like growth inhibitor protein	U5U4R0	Staphylococcus_phage	1.2e-13	32.4
SQE64583.1\|2024870_2025908_+	DNA integration/recombination/inversion protein	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
SQE64584.1\|2025964_2026162_+	phospholipase C	A0A1P8L6H7	Staphylococcus_phage	2.0e-19	100.0
SQE64585.1\|2026406_2026790_+	phospholipase C	A0A1P8L6H7	Staphylococcus_phage	2.6e-71	100.0
SQE64586.1\|2027290_2027926_-	gamma-hemolysin component B	A0A2I6PER8	Staphylococcus_phage	1.1e-15	32.5
SQE64587.1\|2028043_2028307_-	gamma-hemolysin component B	NA	NA	NA	NA
SQE64588.1\|2028328_2029381_-	Leukocidin S subunit	A0A1X9IGW5	Staphylococcus_phage	2.5e-36	34.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LS483308

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection