CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483309	Staphylococcus aureus strain NCTC9944 genome assembly, chromosome: 1	10 crisprs	cas3,DEDDh,DinG,csa3,WYL	10	3	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483309_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_1

459596-459696

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_1

>merge|LS483309|1|459596-459696|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>LS483309|1|1|459596-459696|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE59794.1\|450878_451130_+\|transglycosylase-associated-family-protein	unknown	unknown	gnl\|CDD\|225170
LS483309.1\|SQE59815.1\|459712_460669_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|235334
LS483309.1\|SQE59818.1\|460786_461449_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE59791.1\|450315_450579_-\|XRE-family-transcription-regulator,-putative	unknown	unknown	gnl\|CDD\|238045
LS483309.1\|SQE59835.1\|468715_468916_-\|Domain-of-uncharacterised-function-(DUF3173)	unknown	unknown	gnl\|CDD\|371495
LS483309.1\|SQE59833.1\|467495_468689_-\|integrase-like-protein	unknown	unknown	gnl\|CDD\|271189
LS483309.1\|SQE59808.1\|455450_456020_-\|Alkyl-hydroperoxide-reductase-protein-C	unknown	unknown	gnl\|CDD\|211789
LS483309.1\|SQE59800.1\|452840_453467_-\|lipoprotein	unknown	unknown	gnl\|CDD\|380196
LS483309.1\|SQE59823.1\|462511_463090_+\|Xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
LS483309.1\|SQE59810.1\|456460_457267_+\|Chromate-reductase	unknown	unknown	gnl\|CDD\|380322
LS483309.1\|SQE59805.1\|453911_455435_-\|Alkyl-hydroperoxide-reductase-protein-F	unknown	unknown	gnl\|CDD\|237942
LS483309.1\|SQE59828.1\|464395_465862_+\|Inosine-5-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
LS483309.1\|SQE59796.1\|451555_452137_+\|truncated-phosphoglycerate-mutase-family-protein	unknown	unknown	gnl\|CDD\|223483
LS483309.1\|SQE59837.1\|469413_469644_-\|Polyribonucleotide-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|378900
LS483309.1\|SQE59803.1\|453539_453797_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE59830.1\|465886_467428_+\|GMP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|234614
LS483309.1\|SQE59820.1\|461591_461999_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|378584
LS483309.1\|SQE59798.1\|452202_452589_-\|membrane-spanning-protein	unknown	unknown	unknown
LS483309.1\|SQE59826.1\|463089_464358_+\|Xanthine-permease	unknown	unknown	gnl\|CDD\|274468
LS483309.1\|SQE59813.1\|457347_458736_-\|Sodium:dicarboxylate-symporter-family-protein	unknown	unknown	gnl\|CDD\|224736

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE59794.1\|450878_451130_+\|transglycosylase-associated-family-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
LS483309.1\|SQE59815.1\|459712_460669_-\|DNA-binding-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
LS483309.1\|SQE59833.1\|467495_468689_-\|integrase-like-protein	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.36769e-47
LS483309.1\|SQE59791.1\|450315_450579_-\|XRE-family-transcription-regulator,-putative	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.0037414
LS483309.1\|SQE59835.1\|468715_468916_-\|Domain-of-uncharacterised-function-(DUF3173)	gnl\|CDD\|371495	pfam11372, DUF3173, Domain of unknown function (DUF3173). This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).	2.02242e-22
LS483309.1\|SQE59808.1\|455450_456020_-\|Alkyl-hydroperoxide-reductase-protein-C	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
LS483309.1\|SQE59800.1\|452840_453467_-\|lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
LS483309.1\|SQE59823.1\|462511_463090_+\|Xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
LS483309.1\|SQE59810.1\|456460_457267_+\|Chromate-reductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.24225e-88
LS483309.1\|SQE59805.1\|453911_455435_-\|Alkyl-hydroperoxide-reductase-protein-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
LS483309.1\|SQE59828.1\|464395_465862_+\|Inosine-5-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
LS483309.1\|SQE59796.1\|451555_452137_+\|truncated-phosphoglycerate-mutase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
LS483309.1\|SQE59837.1\|469413_469644_-\|Polyribonucleotide-nucleotidyltransferase	gnl\|CDD\|378900	pfam12645, HTH_16, Helix-turn-helix domain. This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.	2.04673e-25
LS483309.1\|SQE59830.1\|465886_467428_+\|GMP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
LS483309.1\|SQE59820.1\|461591_461999_-\|transcriptional-regulator	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
LS483309.1\|SQE59826.1\|463089_464358_+\|Xanthine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
LS483309.1\|SQE59813.1\|457347_458736_-\|Sodium:dicarboxylate-symporter-family-protein	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0

>LS483309.1|SQE59813.1|457347_458736_-|Sodium:dicarboxylate-symporter-family-protein
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>LS483309.1|SQE59810.1|456460_457267_+|Chromate-reductase
MQYEDFKLIVKYRGVGNVSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>LS483309.1|SQE59808.1|455450_456020_-|Alkyl-hydroperoxide-reductase-protein-C
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>LS483309.1|SQE59805.1|453911_455435_-|Alkyl-hydroperoxide-reductase-protein-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>LS483309.1|SQE59803.1|453539_453797_-|Uncharacterised-protein
MLKVCTSRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLVQPIMQLFIDKAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>LS483309.1|SQE59800.1|452840_453467_-|lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>LS483309.1|SQE59798.1|452202_452589_-|membrane-spanning-protein
MMKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>LS483309.1|SQE59796.1|451555_452137_+|truncated-phosphoglycerate-mutase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>LS483309.1|SQE59794.1|450878_451130_+|transglycosylase-associated-family-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>LS483309.1|SQE59791.1|450315_450579_-|XRE-family-transcription-regulator,-putative
MNMHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHHHEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK
>LS483309.1|SQE59815.1|459712_460669_-|DNA-binding-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>LS483309.1|SQE59818.1|460786_461449_-|Uncharacterised-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>LS483309.1|SQE59820.1|461591_461999_-|transcriptional-regulator
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>LS483309.1|SQE59823.1|462511_463090_+|Xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>LS483309.1|SQE59826.1|463089_464358_+|Xanthine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>LS483309.1|SQE59828.1|464395_465862_+|Inosine-5-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>LS483309.1|SQE59830.1|465886_467428_+|GMP-synthase-(glutamine-hydrolyzing)
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>LS483309.1|SQE59833.1|467495_468689_-|integrase-like-protein
MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEAREEYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFDKMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGNVKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDIDFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQTDFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDRLGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKEMKKVQ
>LS483309.1|SQE59835.1|468715_468916_-|Domain-of-uncharacterised-function-(DUF3173)
MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLDRVPREAVEEILGIRFSNENRSE
>LS483309.1|SQE59837.1|469413_469644_-|Polyribonucleotide-nucleotidyltransferase
MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMTDEYGNSHMVIDETLRGRMETKLISKILSFEIK

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Crispr_ID: LS483309_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_2

732605-732697

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_2

>merge|LS483309|2|732605-732697|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>LS483309|2|2|732605-732697|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE60371.1\|734805_735525_+\|L-2-haloalkanoic-acid-dehalogenase	unknown	unknown	gnl\|CDD\|223943
LS483309.1\|SQE60361.1\|729288_729705_+\|Uncharacterized-beta-barrel-protein-ywiB	unknown	unknown	gnl\|CDD\|226896
LS483309.1\|SQE60348.1\|724439_724976_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-ywqN	unknown	unknown	gnl\|CDD\|223728
LS483309.1\|SQE60363.1\|729701_731363_+\|Arginyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234964
LS483309.1\|SQE60351.1\|725144_725621_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|366181
LS483309.1\|SQE60377.1\|737112_737829_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE60375.1\|736444_736951_+\|exported-protein	unknown	unknown	unknown
LS483309.1\|SQE60384.1\|740358_741288_-\|Integral-membrane-protein	unknown	unknown	gnl\|CDD\|225778
LS483309.1\|SQE60355.1\|726998_727505_+\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|378039
LS483309.1\|SQE60359.1\|729088_729196_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE60347.1\|723290_724229_+\|Oxidoreductase-ion-channel	unknown	unknown	gnl\|CDD\|381309
LS483309.1\|SQE60353.1\|725660_726956_+\|Deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl\|CDD\|224004
LS483309.1\|SQE60367.1\|732765_733653_+\|Periplasmic-binding-protein	unknown	unknown	gnl\|CDD\|238563
LS483309.1\|SQE60381.1\|739036_739411_-\|Staphylococcal-accessory-regulator-A-(SarA)	unknown	unknown	gnl\|CDD\|130944
LS483309.1\|SQE60386.1\|741482_741707_-\|Protein-of-uncharacterised-function-(DUF2922)	unknown	unknown	gnl\|CDD\|378571
LS483309.1\|SQE60373.1\|735508_736309_+\|3-oxoadipate-enol-lactonase	unknown	unknown	gnl\|CDD\|223669
LS483309.1\|SQE60357.1\|728003_729014_+\|Alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
LS483309.1\|SQE60365.1\|731751_732387_+\|endonuclease-III-domain-protein	unknown	unknown	gnl\|CDD\|225140
LS483309.1\|SQE60379.1\|737997_738786_+\|hypothetical-esterase/lipase	unknown	unknown	gnl\|CDD\|223669
LS483309.1\|SQE60369.1\|733764_734751_+\|transporter	unknown	unknown	gnl\|CDD\|376439

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE60371.1\|734805_735525_+\|L-2-haloalkanoic-acid-dehalogenase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
LS483309.1\|SQE60361.1\|729288_729705_+\|Uncharacterized-beta-barrel-protein-ywiB	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
LS483309.1\|SQE60348.1\|724439_724976_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-ywqN	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
LS483309.1\|SQE60363.1\|729701_731363_+\|Arginyl-tRNA-synthetase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
LS483309.1\|SQE60351.1\|725144_725621_+\|acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
LS483309.1\|SQE60384.1\|740358_741288_-\|Integral-membrane-protein	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37
LS483309.1\|SQE60355.1\|726998_727505_+\|Putative-cytosolic-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	1.08203e-97
LS483309.1\|SQE60347.1\|723290_724229_+\|Oxidoreductase-ion-channel	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
LS483309.1\|SQE60353.1\|725660_726956_+\|Deoxyguanosinetriphosphate-triphosphohydrolase	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
LS483309.1\|SQE60367.1\|732765_733653_+\|Periplasmic-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
LS483309.1\|SQE60381.1\|739036_739411_-\|Staphylococcal-accessory-regulator-A-(SarA)	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
LS483309.1\|SQE60386.1\|741482_741707_-\|Protein-of-uncharacterised-function-(DUF2922)	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
LS483309.1\|SQE60373.1\|735508_736309_+\|3-oxoadipate-enol-lactonase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.35732e-24
LS483309.1\|SQE60357.1\|728003_729014_+\|Alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
LS483309.1\|SQE60365.1\|731751_732387_+\|endonuclease-III-domain-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
LS483309.1\|SQE60379.1\|737997_738786_+\|hypothetical-esterase/lipase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.87236e-34
LS483309.1\|SQE60369.1\|733764_734751_+\|transporter	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.17074e-49

>LS483309.1|SQE60365.1|731751_732387_+|endonuclease-III-domain-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>LS483309.1|SQE60363.1|729701_731363_+|Arginyl-tRNA-synthetase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>LS483309.1|SQE60361.1|729288_729705_+|Uncharacterized-beta-barrel-protein-ywiB
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>LS483309.1|SQE60359.1|729088_729196_+|Uncharacterised-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>LS483309.1|SQE60357.1|728003_729014_+|Alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>LS483309.1|SQE60355.1|726998_727505_+|Putative-cytosolic-protein
MSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>LS483309.1|SQE60353.1|725660_726956_+|Deoxyguanosinetriphosphate-triphosphohydrolase
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>LS483309.1|SQE60351.1|725144_725621_+|acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>LS483309.1|SQE60348.1|724439_724976_+|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-ywqN
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>LS483309.1|SQE60347.1|723290_724229_+|Oxidoreductase-ion-channel
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>LS483309.1|SQE60367.1|732765_733653_+|Periplasmic-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>LS483309.1|SQE60369.1|733764_734751_+|transporter
MNVIIDERKENAMTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>LS483309.1|SQE60371.1|734805_735525_+|L-2-haloalkanoic-acid-dehalogenase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>LS483309.1|SQE60373.1|735508_736309_+|3-oxoadipate-enol-lactonase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMSGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>LS483309.1|SQE60375.1|736444_736951_+|exported-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>LS483309.1|SQE60377.1|737112_737829_+|Uncharacterised-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>LS483309.1|SQE60379.1|737997_738786_+|hypothetical-esterase/lipase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGIVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>LS483309.1|SQE60381.1|739036_739411_-|Staphylococcal-accessory-regulator-A-(SarA)
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>LS483309.1|SQE60384.1|740358_741288_-|Integral-membrane-protein
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>LS483309.1|SQE60386.1|741482_741707_-|Protein-of-uncharacterised-function-(DUF2922)
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: LS483309_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_3

848349-848431

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_3

>merge|LS483309|3|848349-848431|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>LS483309|3|3|848349-848431|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE60691.1\|858320_859334_+\|FatD	unknown	unknown	gnl\|CDD\|226965
LS483309.1\|SQE60598.1\|835243_835954_+\|Urea-amidolyase	unknown	unknown	gnl\|CDD\|224960
LS483309.1\|SQE60602.1\|837415_839356_+\|glycerol-phosphate-lipoteichoic-acid-synthase	unknown	unknown	gnl\|CDD\|224287
LS483309.1\|SQE60620.1\|850066_851572_-\|Di/tripeptide-permease-YjdL	unknown	unknown	gnl\|CDD\|225646
LS483309.1\|SQE60687.1\|854460_856566_+\|ribonucleotide-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
LS483309.1\|SQE60615.1\|847657_848200_+\|5'-3'-deoxyribonucleotidase,-putative	unknown	unknown	gnl\|CDD\|226895
LS483309.1\|SQE60604.1\|839632_841510_+\|ABC-transporter	unknown	unknown	gnl\|CDD\|223562
LS483309.1\|SQE60618.1\|848879_849797_-\|Transcription-regulator-(contains-diacylglycerol-kinase-catalytic-domain)	unknown	unknown	gnl\|CDD\|224513
LS483309.1\|SQE60611.1\|844494_846009_+\|Osmotically-activated-L-carnitine/choline-ABC-transporter,-permease-protein-OpuCB	unknown	unknown	gnl\|CDD\|270328
LS483309.1\|SQE60680.1\|851912_852413_-\|NADPH-dependent-preQ0-reductase	unknown	unknown	gnl\|CDD\|223851
LS483309.1\|SQE60693.1\|859320_860277_+\|Iron-compound-ABC-uptake-transporter-permease-protein	unknown	unknown	gnl\|CDD\|226964
LS483309.1\|SQE60600.1\|835937_836942_+\|allophanate-hydrolase-subunit-2-family-protein	unknown	unknown	gnl\|CDD\|224895
LS483309.1\|SQE60695.1\|860273_861035_+\|Iron-compound-ABC-uptake-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226963
LS483309.1\|SQE60685.1\|854099_854498_+\|Nrdi	unknown	unknown	gnl\|CDD\|224694
LS483309.1\|SQE60682.1\|852432_853299_-\|Integral-membrane-domain-protein	unknown	unknown	gnl\|CDD\|223769
LS483309.1\|SQE60689.1\|856683_857655_+\|ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
LS483309.1\|SQE60606.1\|841521_843303_+\|ATP-dependent-DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
LS483309.1\|SQE60596.1\|834275_834884_+\|Aminodeoxychorismate-lyase-PabAc	unknown	unknown	gnl\|CDD\|376449
LS483309.1\|SQE60609.1\|843524_844502_+\|Glycine-betaine-ABC-transport-system,-ATP-binding-protein-OpuAA	unknown	unknown	gnl\|CDD\|224050
LS483309.1\|SQE60613.1\|846248_847307_+\|histidinol-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|235106

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE60691.1\|858320_859334_+\|FatD	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.27667e-149
LS483309.1\|SQE60598.1\|835243_835954_+\|Urea-amidolyase	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.29969e-94
LS483309.1\|SQE60602.1\|837415_839356_+\|glycerol-phosphate-lipoteichoic-acid-synthase	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
LS483309.1\|SQE60620.1\|850066_851572_-\|Di/tripeptide-permease-YjdL	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
LS483309.1\|SQE60687.1\|854460_856566_+\|ribonucleotide-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
LS483309.1\|SQE60615.1\|847657_848200_+\|5'-3'-deoxyribonucleotidase,-putative	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.15481e-107
LS483309.1\|SQE60604.1\|839632_841510_+\|ABC-transporter	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
LS483309.1\|SQE60618.1\|848879_849797_-\|Transcription-regulator-(contains-diacylglycerol-kinase-catalytic-domain)	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.10512e-78
LS483309.1\|SQE60611.1\|844494_846009_+\|Osmotically-activated-L-carnitine/choline-ABC-transporter,-permease-protein-OpuCB	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
LS483309.1\|SQE60680.1\|851912_852413_-\|NADPH-dependent-preQ0-reductase	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
LS483309.1\|SQE60693.1\|859320_860277_+\|Iron-compound-ABC-uptake-transporter-permease-protein	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	4.81847e-122
LS483309.1\|SQE60600.1\|835937_836942_+\|allophanate-hydrolase-subunit-2-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
LS483309.1\|SQE60695.1\|860273_861035_+\|Iron-compound-ABC-uptake-transporter-ATP-binding-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	3.31412e-150
LS483309.1\|SQE60685.1\|854099_854498_+\|Nrdi	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
LS483309.1\|SQE60682.1\|852432_853299_-\|Integral-membrane-domain-protein	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.8323e-10
LS483309.1\|SQE60689.1\|856683_857655_+\|ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
LS483309.1\|SQE60606.1\|841521_843303_+\|ATP-dependent-DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
LS483309.1\|SQE60596.1\|834275_834884_+\|Aminodeoxychorismate-lyase-PabAc	gnl\|CDD\|376449	pfam01063, Aminotran_4, Amino-transferase class IV. The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.	5.60043e-39
LS483309.1\|SQE60609.1\|843524_844502_+\|Glycine-betaine-ABC-transport-system,-ATP-binding-protein-OpuAA	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.80291e-155
LS483309.1\|SQE60613.1\|846248_847307_+\|histidinol-phosphate-aminotransferase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0

>LS483309.1|SQE60615.1|847657_848200_+|5'-3'-deoxyribonucleotidase,-putative
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPYAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>LS483309.1|SQE60613.1|846248_847307_+|histidinol-phosphate-aminotransferase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>LS483309.1|SQE60611.1|844494_846009_+|Osmotically-activated-L-carnitine/choline-ABC-transporter,-permease-protein-OpuCB
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>LS483309.1|SQE60609.1|843524_844502_+|Glycine-betaine-ABC-transport-system,-ATP-binding-protein-OpuAA
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>LS483309.1|SQE60606.1|841521_843303_+|ATP-dependent-DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>LS483309.1|SQE60604.1|839632_841510_+|ABC-transporter
MEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREENEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDDQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>LS483309.1|SQE60602.1|837415_839356_+|glycerol-phosphate-lipoteichoic-acid-synthase
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>LS483309.1|SQE60600.1|835937_836942_+|allophanate-hydrolase-subunit-2-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>LS483309.1|SQE60598.1|835243_835954_+|Urea-amidolyase
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>LS483309.1|SQE60596.1|834275_834884_+|Aminodeoxychorismate-lyase-PabAc
MQLFETMKIDNGHIPRLTYHTNRIKCSSERLNFKFDEHAWRNELNDVTTKYHSGQYRLKIVLNAESKFETIVSPLPEKSSFTAKFQVLPKVVNPTFIKNKTTERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLIDSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL
>LS483309.1|SQE60618.1|848879_849797_-|Transcription-regulator-(contains-diacylglycerol-kinase-catalytic-domain)
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>LS483309.1|SQE60620.1|850066_851572_-|Di/tripeptide-permease-YjdL
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>LS483309.1|SQE60680.1|851912_852413_-|NADPH-dependent-preQ0-reductase
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>LS483309.1|SQE60682.1|852432_853299_-|Integral-membrane-domain-protein
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>LS483309.1|SQE60685.1|854099_854498_+|Nrdi
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>LS483309.1|SQE60687.1|854460_856566_+|ribonucleotide-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>LS483309.1|SQE60689.1|856683_857655_+|ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>LS483309.1|SQE60691.1|858320_859334_+|FatD
MIMIIINLKGEKFVMKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ
>LS483309.1|SQE60693.1|859320_860277_+|Iron-compound-ABC-uptake-transporter-permease-protein
MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFILIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVYLNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPESFLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISYEKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWISLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ
>LS483309.1|SQE60695.1|860273_861035_+|Iron-compound-ABC-uptake-transporter-ATP-binding-protein
MIQVENLTKTINNQMILEDISIDIEKGKLTSLIGPNGAGKSTLLSAICRLIRFENGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFPYSKGRLTKEDHDIVNDALDLLQLQDIRNRNIKSLSGGQRQRAYIAMTIAQDTEYILLDEPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGQLVKSDLKDNVIQSSVLSDLYDMNIQIEHIRNQRICLYFKD

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Crispr_ID: LS483309_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_4

894853-894938

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_4

>merge|LS483309|4|894853-894938|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>LS483309|4|4|894853-894938|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE60730.1\|891557_892043_+\|O-acetyltransferase	unknown	unknown	gnl\|CDD\|100053
LS483309.1\|SQE60729.1\|890710_891550_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
LS483309.1\|SQE60725.1\|883766_884003_+\|putative-DUF2198-containing-protein	unknown	unknown	gnl\|CDD\|227234
LS483309.1\|SQE60726.1\|884271_886257_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
LS483309.1\|SQE60733.1\|893555_894491_+\|Thioredoxin-reductase	unknown	unknown	gnl\|CDD\|273540
LS483309.1\|SQE60735.1\|896278_897127_+\|2-phospho-L-lactate-transferase-like-protein	unknown	unknown	gnl\|CDD\|211689
LS483309.1\|SQE60724.1\|883119_883770_+\|hydrolase	unknown	unknown	gnl\|CDD\|378993
LS483309.1\|SQE60736.1\|897382_898327_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	unknown	unknown	gnl\|CDD\|273194
LS483309.1\|SQE60737.1\|898899_899487_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
LS483309.1\|SQE60728.1\|889772_890705_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
LS483309.1\|SQE60740.1\|902606_903620_+\|Central-glycolytic-genes-regulator	unknown	unknown	gnl\|CDD\|225263
LS483309.1\|SQE60734.1\|895370_896282_+\|ATP-binding-protein-UPF0042,-contains-P-loop	unknown	unknown	gnl\|CDD\|224574
LS483309.1\|SQE60742.1\|904821_906012_+\|Phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
LS483309.1\|SQE60743.1\|906133_906895_+\|triosephosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
LS483309.1\|SQE60738.1\|899729_900632_-\|Cell-division-inhibitor	unknown	unknown	gnl\|CDD\|224015
LS483309.1\|SQE60727.1\|886264_889111_+\|Excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
LS483309.1\|SQE60739.1\|901334_901964_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|234750
LS483309.1\|SQE60731.1\|892050_892905_+\|TPR-domain-protein	unknown	unknown	gnl\|CDD\|276808
LS483309.1\|SQE60732.1\|892889_893489_+\|TPR-domain-protein	unknown	unknown	unknown
LS483309.1\|SQE60741.1\|903672_904683_+\|NAD-dependent-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE60730.1\|891557_892043_+\|O-acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
LS483309.1\|SQE60729.1\|890710_891550_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
LS483309.1\|SQE60725.1\|883766_884003_+\|putative-DUF2198-containing-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
LS483309.1\|SQE60726.1\|884271_886257_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
LS483309.1\|SQE60733.1\|893555_894491_+\|Thioredoxin-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
LS483309.1\|SQE60735.1\|896278_897127_+\|2-phospho-L-lactate-transferase-like-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.4537e-156
LS483309.1\|SQE60724.1\|883119_883770_+\|hydrolase	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
LS483309.1\|SQE60736.1\|897382_898327_+\|sporulation-Regulator-WhiA-C-terminal-domain-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
LS483309.1\|SQE60737.1\|898899_899487_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
LS483309.1\|SQE60731.1\|892050_892905_+\|TPR-domain-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	6.75194e-06
LS483309.1\|SQE60740.1\|902606_903620_+\|Central-glycolytic-genes-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
LS483309.1\|SQE60734.1\|895370_896282_+\|ATP-binding-protein-UPF0042,-contains-P-loop	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
LS483309.1\|SQE60742.1\|904821_906012_+\|Phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
LS483309.1\|SQE60743.1\|906133_906895_+\|triosephosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
LS483309.1\|SQE60738.1\|899729_900632_-\|Cell-division-inhibitor	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
LS483309.1\|SQE60727.1\|886264_889111_+\|Excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
LS483309.1\|SQE60739.1\|901334_901964_+\|Uncharacterised-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
LS483309.1\|SQE60728.1\|889772_890705_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
LS483309.1\|SQE60741.1\|903672_904683_+\|NAD-dependent-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0

>LS483309.1|SQE60733.1|893555_894491_+|Thioredoxin-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>LS483309.1|SQE60732.1|892889_893489_+|TPR-domain-protein
MYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLSDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>LS483309.1|SQE60731.1|892050_892905_+|TPR-domain-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGNFYQFKCTML
>LS483309.1|SQE60730.1|891557_892043_+|O-acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>LS483309.1|SQE60729.1|890710_891550_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>LS483309.1|SQE60728.1|889772_890705_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>LS483309.1|SQE60727.1|886264_889111_+|Excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>LS483309.1|SQE60726.1|884271_886257_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>LS483309.1|SQE60725.1|883766_884003_+|putative-DUF2198-containing-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>LS483309.1|SQE60724.1|883119_883770_+|hydrolase
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>LS483309.1|SQE60734.1|895370_896282_+|ATP-binding-protein-UPF0042,-contains-P-loop
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>LS483309.1|SQE60735.1|896278_897127_+|2-phospho-L-lactate-transferase-like-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKNMKKNILNQLKLIRLNLKKKA
>LS483309.1|SQE60736.1|897382_898327_+|sporulation-Regulator-WhiA-C-terminal-domain-protein
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>LS483309.1|SQE60737.1|898899_899487_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>LS483309.1|SQE60738.1|899729_900632_-|Cell-division-inhibitor
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>LS483309.1|SQE60739.1|901334_901964_+|Uncharacterised-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>LS483309.1|SQE60740.1|902606_903620_+|Central-glycolytic-genes-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>LS483309.1|SQE60741.1|903672_904683_+|NAD-dependent-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>LS483309.1|SQE60742.1|904821_906012_+|Phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>LS483309.1|SQE60743.1|906133_906895_+|triosephosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: LS483309_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_5

938042-938123

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_5

>merge|LS483309|5|938042-938123|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>LS483309|5|5|938042-938123|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE60786.1\|934187_934751_+\|3-dehydroquinate-dehydratase-I-AroC-I	unknown	unknown	gnl\|CDD\|184156
LS483309.1\|SQE60803.1\|939058_939355_+\|Thioredoxin	unknown	unknown	gnl\|CDD\|239245
LS483309.1\|SQE60788.1\|934833_935373_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380312
LS483309.1\|SQE60812.1\|942510_942705_+\|CsbD-like-protein	unknown	unknown	gnl\|CDD\|225777
LS483309.1\|SQE60810.1\|941335_942157_+\|Methionine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
LS483309.1\|SQE60779.1\|932572_933067_-\|lactococcal-prophage-ps3-protein-05	unknown	unknown	gnl\|CDD\|372596
LS483309.1\|SQE60796.1\|936944_937058_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE60798.1\|937059_937938_+\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|226395
LS483309.1\|SQE60781.1\|933465_933888_-\|Organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
LS483309.1\|SQE60817.1\|944116_944878_+\|iron-sulfur-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
LS483309.1\|SQE60808.1\|940622_941318_+\|Methionine-ABC-transporter-permease-protein	unknown	unknown	gnl\|CDD\|224922
LS483309.1\|SQE60791.1\|935986_936343_+\|Arsenate-reductase	unknown	unknown	gnl\|CDD\|239334
LS483309.1\|SQE60822.1\|946397_947639_+\|Selenocysteine-lyase	unknown	unknown	gnl\|CDD\|131034
LS483309.1\|SQE60800.1\|938676_939066_+\|DNA-primase/-small-primase-like-protein	unknown	unknown	gnl\|CDD\|224572
LS483309.1\|SQE60806.1\|939604_940630_+\|Methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
LS483309.1\|SQE60790.1\|935522_935843_-\|Thioredoxin	unknown	unknown	gnl\|CDD\|239245
LS483309.1\|SQE60820.1\|944975_946283_+\|Iron-sulfur-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
LS483309.1\|SQE60794.1\|936500_936881_+\|Glycine-cleavage-system-H-protein	unknown	unknown	gnl\|CDD\|234918
LS483309.1\|SQE60783.1\|934035_934128_+\|3-dehydroquinate-dehydratase-I-AroC-I	unknown	unknown	gnl\|CDD\|184156
LS483309.1\|SQE60815.1\|942937_943789_-\|membrane-protein	unknown	unknown	gnl\|CDD\|224946

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE60786.1\|934187_934751_+\|3-dehydroquinate-dehydratase-I-AroC-I	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.82113e-122
LS483309.1\|SQE60803.1\|939058_939355_+\|Thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
LS483309.1\|SQE60788.1\|934833_935373_+\|nitroreductase-family-protein	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
LS483309.1\|SQE60812.1\|942510_942705_+\|CsbD-like-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
LS483309.1\|SQE60810.1\|941335_942157_+\|Methionine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
LS483309.1\|SQE60779.1\|932572_933067_-\|lactococcal-prophage-ps3-protein-05	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
LS483309.1\|SQE60783.1\|934035_934128_+\|3-dehydroquinate-dehydratase-I-AroC-I	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	2.00793e-05
LS483309.1\|SQE60798.1\|937059_937938_+\|Putative-cytosolic-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
LS483309.1\|SQE60781.1\|933465_933888_-\|Organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
LS483309.1\|SQE60817.1\|944116_944878_+\|iron-sulfur-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
LS483309.1\|SQE60791.1\|935986_936343_+\|Arsenate-reductase	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
LS483309.1\|SQE60822.1\|946397_947639_+\|Selenocysteine-lyase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
LS483309.1\|SQE60800.1\|938676_939066_+\|DNA-primase/-small-primase-like-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	6.789e-37
LS483309.1\|SQE60806.1\|939604_940630_+\|Methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
LS483309.1\|SQE60790.1\|935522_935843_-\|Thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
LS483309.1\|SQE60820.1\|944975_946283_+\|Iron-sulfur-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
LS483309.1\|SQE60794.1\|936500_936881_+\|Glycine-cleavage-system-H-protein	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
LS483309.1\|SQE60808.1\|940622_941318_+\|Methionine-ABC-transporter-permease-protein	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
LS483309.1\|SQE60815.1\|942937_943789_-\|membrane-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76

>LS483309.1|SQE60798.1|937059_937938_+|Putative-cytosolic-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>LS483309.1|SQE60796.1|936944_937058_+|Uncharacterised-protein
MKEKLLGTIIWSIATFYYSRMMEIMNLAILKIKIGGS
>LS483309.1|SQE60794.1|936500_936881_+|Glycine-cleavage-system-H-protein
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>LS483309.1|SQE60791.1|935986_936343_+|Arsenate-reductase
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>LS483309.1|SQE60790.1|935522_935843_-|Thioredoxin
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>LS483309.1|SQE60788.1|934833_935373_+|nitroreductase-family-protein
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>LS483309.1|SQE60786.1|934187_934751_+|3-dehydroquinate-dehydratase-I-AroC-I
MITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>LS483309.1|SQE60783.1|934035_934128_+|3-dehydroquinate-dehydratase-I-AroC-I
MTHVEVVATIAPQLSIEETLIQKLIIVLMQ
>LS483309.1|SQE60781.1|933465_933888_-|Organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>LS483309.1|SQE60779.1|932572_933067_-|lactococcal-prophage-ps3-protein-05
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>LS483309.1|SQE60800.1|938676_939066_+|DNA-primase/-small-primase-like-protein
MMAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>LS483309.1|SQE60803.1|939058_939355_+|Thioredoxin
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>LS483309.1|SQE60806.1|939604_940630_+|Methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>LS483309.1|SQE60808.1|940622_941318_+|Methionine-ABC-transporter-permease-protein
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>LS483309.1|SQE60810.1|941335_942157_+|Methionine-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>LS483309.1|SQE60812.1|942510_942705_+|CsbD-like-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>LS483309.1|SQE60815.1|942937_943789_-|membrane-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>LS483309.1|SQE60817.1|944116_944878_+|iron-sulfur-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>LS483309.1|SQE60820.1|944975_946283_+|Iron-sulfur-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>LS483309.1|SQE60822.1|946397_947639_+|Selenocysteine-lyase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

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Crispr_ID: LS483309_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_6

986897-987179

Orphan

Consensus_repeat	Method
AAAGNCAGCTNNNNANANNNTGCAAGTTGG	CRT

4 spacers

The CRISPR arrays of LS483309_6

>merge|LS483309|6|986897-987179|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGGCGGGGCCCCAACACAGAGGCTGGCGGAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGAGCCCCGACACAGAGAAATTAGCTCCTCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAAAAAGACAGCAGTAGGATAATTTCAATTTGG

>LS483309|6|1|986897-987179|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	CGGGGCCCCAACACAGAGGCTGGCGG
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGAGCCCCGACACAGAGAAATTAGC
TCCTCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGA
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAA
AAAGACAGCAGTAGGATAATTTCAATTTGG

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE60892.1\|991344_992676_+\|Glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
LS483309.1\|SQE60897.1\|998332_1001986_+\|ATP-dependent-nuclease,-subunit-A	unknown	unknown	gnl\|CDD\|274299
LS483309.1\|SQE60896.1\|994855_998332_+\|helicase-exonuclease-AddAB,-AddB-subunit	unknown	unknown	gnl\|CDD\|213736
LS483309.1\|SQE60890.1\|988419_989799_-\|Argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
LS483309.1\|SQE60882.1\|978036_980442_-\|Na(+)-H(+)-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
LS483309.1\|SQE60891.1\|989788_990994_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
LS483309.1\|SQE60895.1\|994120_994696_+\|Signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
LS483309.1\|SQE60893.1\|993000_993576_+\|SNARE-associated-Golgi-family-protein	unknown	unknown	gnl\|CDD\|223475
LS483309.1\|SQE60894.1\|993580_994105_+\|Signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
LS483309.1\|SQE60881.1\|977615_978044_-\|Na(+)-H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
LS483309.1\|SQE60888.1\|985501_986746_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
LS483309.1\|SQE60880.1\|977274_977616_-\|Na+/H+-antiporter-subunit	unknown	unknown	gnl\|CDD\|181497
LS483309.1\|SQE60889.1\|987248_988178_-\|putative-glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
LS483309.1\|SQE60887.1\|984202_985393_+\|Ornithine-aminotransferase	unknown	unknown	gnl\|CDD\|179736
LS483309.1\|SQE60883.1\|980572_980956_-\|kinase-associated-B-family-protein	unknown	unknown	gnl\|CDD\|378054
LS483309.1\|SQE60885.1\|982028_982406_+\|general-stress-protein-13	unknown	unknown	gnl\|CDD\|224023
LS483309.1\|SQE60884.1\|981019_981613_+\|Peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
LS483309.1\|SQE60879.1\|975785_977282_-\|Na(+)-H(+)-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
LS483309.1\|SQE60886.1\|982767_983895_+\|Putative-NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
LS483309.1\|SQE60898.1\|1002141_1003314_+\|IS256-like-transposase	unknown	unknown	gnl\|CDD\|307151

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE60892.1\|991344_992676_+\|Glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
LS483309.1\|SQE60897.1\|998332_1001986_+\|ATP-dependent-nuclease,-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
LS483309.1\|SQE60896.1\|994855_998332_+\|helicase-exonuclease-AddAB,-AddB-subunit	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
LS483309.1\|SQE60890.1\|988419_989799_-\|Argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
LS483309.1\|SQE60882.1\|978036_980442_-\|Na(+)-H(+)-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
LS483309.1\|SQE60891.1\|989788_990994_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
LS483309.1\|SQE60895.1\|994120_994696_+\|Signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
LS483309.1\|SQE60893.1\|993000_993576_+\|SNARE-associated-Golgi-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
LS483309.1\|SQE60894.1\|993580_994105_+\|Signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
LS483309.1\|SQE60881.1\|977615_978044_-\|Na(+)-H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
LS483309.1\|SQE60888.1\|985501_986746_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
LS483309.1\|SQE60880.1\|977274_977616_-\|Na+/H+-antiporter-subunit	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64
LS483309.1\|SQE60889.1\|987248_988178_-\|putative-glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
LS483309.1\|SQE60887.1\|984202_985393_+\|Ornithine-aminotransferase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
LS483309.1\|SQE60883.1\|980572_980956_-\|kinase-associated-B-family-protein	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
LS483309.1\|SQE60885.1\|982028_982406_+\|general-stress-protein-13	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
LS483309.1\|SQE60884.1\|981019_981613_+\|Peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	6.93398e-65
LS483309.1\|SQE60879.1\|975785_977282_-\|Na(+)-H(+)-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
LS483309.1\|SQE60886.1\|982767_983895_+\|Putative-NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
LS483309.1\|SQE60898.1\|1002141_1003314_+\|IS256-like-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	0

>LS483309.1|SQE60888.1|985501_986746_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>LS483309.1|SQE60887.1|984202_985393_+|Ornithine-aminotransferase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>LS483309.1|SQE60886.1|982767_983895_+|Putative-NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>LS483309.1|SQE60885.1|982028_982406_+|general-stress-protein-13
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>LS483309.1|SQE60884.1|981019_981613_+|Peptidyl-prolyl-cis-trans-isomerase
MTNYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>LS483309.1|SQE60883.1|980572_980956_-|kinase-associated-B-family-protein
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>LS483309.1|SQE60882.1|978036_980442_-|Na(+)-H(+)-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>LS483309.1|SQE60881.1|977615_978044_-|Na(+)-H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>LS483309.1|SQE60880.1|977274_977616_-|Na+/H+-antiporter-subunit
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>LS483309.1|SQE60879.1|975785_977282_-|Na(+)-H(+)-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>LS483309.1|SQE60889.1|987248_988178_-|putative-glycerophosphoryl-diester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>LS483309.1|SQE60890.1|988419_989799_-|Argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>LS483309.1|SQE60891.1|989788_990994_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>LS483309.1|SQE60892.1|991344_992676_+|Glucose-6-phosphate-isomerase
MTHIQLNFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>LS483309.1|SQE60893.1|993000_993576_+|SNARE-associated-Golgi-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>LS483309.1|SQE60894.1|993580_994105_+|Signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>LS483309.1|SQE60895.1|994120_994696_+|Signal-peptidase-I
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>LS483309.1|SQE60896.1|994855_998332_+|helicase-exonuclease-AddAB,-AddB-subunit
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>LS483309.1|SQE60897.1|998332_1001986_+|ATP-dependent-nuclease,-subunit-A
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>LS483309.1|SQE60898.1|1002141_1003314_+|IS256-like-transposase
MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEYIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK

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Crispr_ID: LS483309_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_7

1210063-1210148

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_7

>merge|LS483309|7|1210063-1210148|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>LS483309|7|6|1210063-1210148|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE61093.1\|1209495_1209642_+\|Doubtful-CDS.-No-database-matches	unknown	unknown	unknown
LS483309.1\|SQE61089.1\|1205456_1205807_+\|Involved-in-expression-of-fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|371594
LS483309.1\|SQE61087.1\|1204039_1204546_+\|membrane-protein	unknown	unknown	unknown
LS483309.1\|SQE61102.1\|1217123_1217351_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE61101.1\|1215754_1216816_+\|Arginine/ornithine-antiporter-ArcD	unknown	unknown	gnl\|CDD\|224207
LS483309.1\|SQE61091.1\|1207153_1207387_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE61086.1\|1202966_1203368_-\|FPRL1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
LS483309.1\|SQE61096.1\|1211147_1211873_-\|putative-exotoxin	unknown	unknown	gnl\|CDD\|106307
LS483309.1\|SQE61095.1\|1210323_1211040_-\|Exotoxin	unknown	unknown	gnl\|CDD\|171995
LS483309.1\|SQE61098.1\|1213130_1214132_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
LS483309.1\|SQE61099.1\|1214151_1215087_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
LS483309.1\|SQE61088.1\|1204817_1205303_+\|Extracellular-fibrinogen-binding-protein-Efb	unknown	unknown	gnl\|CDD\|289007
LS483309.1\|SQE61092.1\|1207863_1208823_-\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
LS483309.1\|SQE61090.1\|1206346_1206532_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE61094.1\|1209625_1209823_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE61104.1\|1218851_1219040_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|225382
LS483309.1\|SQE61085.1\|1202268_1202598_+\|Extracellular-fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|289007
LS483309.1\|SQE61103.1\|1217655_1218603_-\|putative-permease	unknown	unknown	gnl\|CDD\|187765
LS483309.1\|SQE61097.1\|1211967_1212693_-\|Exotoxin	unknown	unknown	gnl\|CDD\|171855
LS483309.1\|SQE61100.1\|1215258_1215708_+\|APC-family-amino-acid-polyamine-organocation-transporter,-antiporter	unknown	unknown	gnl\|CDD\|224207

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE61089.1\|1205456_1205807_+\|Involved-in-expression-of-fibrinogen-binding-protein	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
LS483309.1\|SQE61104.1\|1218851_1219040_+\|DNA-binding-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
LS483309.1\|SQE61101.1\|1215754_1216816_+\|Arginine/ornithine-antiporter-ArcD	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	6.48354e-151
LS483309.1\|SQE61086.1\|1202966_1203368_-\|FPRL1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	3.87075e-77
LS483309.1\|SQE61096.1\|1211147_1211873_-\|putative-exotoxin	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
LS483309.1\|SQE61095.1\|1210323_1211040_-\|Exotoxin	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
LS483309.1\|SQE61085.1\|1202268_1202598_+\|Extracellular-fibrinogen-binding-protein	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	4.63429e-22
LS483309.1\|SQE61099.1\|1214151_1215087_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
LS483309.1\|SQE61088.1\|1204817_1205303_+\|Extracellular-fibrinogen-binding-protein-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	1.1135e-27
LS483309.1\|SQE61092.1\|1207863_1208823_-\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.62736e-140
LS483309.1\|SQE61098.1\|1213130_1214132_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
LS483309.1\|SQE61103.1\|1217655_1218603_-\|putative-permease	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	1.39126e-83
LS483309.1\|SQE61097.1\|1211967_1212693_-\|Exotoxin	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
LS483309.1\|SQE61100.1\|1215258_1215708_+\|APC-family-amino-acid-polyamine-organocation-transporter,-antiporter	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	1.19089e-33

>LS483309.1|SQE61094.1|1209625_1209823_+|Uncharacterised-protein
MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>LS483309.1|SQE61093.1|1209495_1209642_+|Doubtful-CDS.-No-database-matches
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>LS483309.1|SQE61092.1|1207863_1208823_-|alpha-hemolysin
MKTHIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>LS483309.1|SQE61091.1|1207153_1207387_-|Uncharacterised-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>LS483309.1|SQE61090.1|1206346_1206532_-|Uncharacterised-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>LS483309.1|SQE61089.1|1205456_1205807_+|Involved-in-expression-of-fibrinogen-binding-protein
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>LS483309.1|SQE61088.1|1204817_1205303_+|Extracellular-fibrinogen-binding-protein-Efb
MIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>LS483309.1|SQE61087.1|1204039_1204546_+|membrane-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>LS483309.1|SQE61086.1|1202966_1203368_-|FPRL1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
>LS483309.1|SQE61085.1|1202268_1202598_+|Extracellular-fibrinogen-binding-protein
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNVEAAKKYDQYQTNFKKQVNKKVVDAQKAVNFFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>LS483309.1|SQE61095.1|1210323_1211040_-|Exotoxin
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>LS483309.1|SQE61096.1|1211147_1211873_-|putative-exotoxin
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>LS483309.1|SQE61097.1|1211967_1212693_-|Exotoxin
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>LS483309.1|SQE61098.1|1213130_1214132_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>LS483309.1|SQE61099.1|1214151_1215087_+|carbamate-kinase
MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>LS483309.1|SQE61100.1|1215258_1215708_+|APC-family-amino-acid-polyamine-organocation-transporter,-antiporter
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSF
>LS483309.1|SQE61101.1|1215754_1216816_+|Arginine/ornithine-antiporter-ArcD
MLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>LS483309.1|SQE61102.1|1217123_1217351_+|Uncharacterised-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>LS483309.1|SQE61103.1|1217655_1218603_-|putative-permease
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLKNVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>LS483309.1|SQE61104.1|1218851_1219040_+|DNA-binding-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN

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Crispr_ID: LS483309_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_8

2316620-2316770

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of LS483309_8

>merge|LS483309|8|2316620-2316770|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCTTTCTA

>LS483309|8|7|2316620-2316770|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTTAGGGGCTCTTATGCA	GTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGGGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE62148.1\|2314264_2315245_+\|Cobalt-zinc-cadmium-resistance-protein	unknown	unknown	gnl\|CDD\|224151
LS483309.1\|SQE62151.1\|2317892_2319029_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
LS483309.1\|SQE62149.1\|2315510_2316602_+\|Lytic-regulatory-protein	unknown	unknown	unknown
LS483309.1\|SQE62147.1\|2313942_2314263_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
LS483309.1\|SQE62154.1\|2322053_2323859_-\|glucosamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
LS483309.1\|SQE62143.1\|2309446_2310820_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
LS483309.1\|SQE62150.1\|2317630_2317834_-\|resolvase-like-protein	unknown	unknown	gnl\|CDD\|239737
LS483309.1\|SQE62157.1\|2328256_2328691_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
LS483309.1\|SQE62155.1\|2324539_2326078_+\|PTS-system,-mannitol-specific-IIBC-component	unknown	unknown	gnl\|CDD\|225123
LS483309.1\|SQE62158.1\|2328690_2329797_+\|Mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
LS483309.1\|SQE62142.1\|2308575_2308989_-\|thiol-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|225556
LS483309.1\|SQE62159.1\|2330115_2337612_-\|FmtB-protein	unknown	unknown	gnl\|CDD\|275089
LS483309.1\|SQE62156.1\|2326112_2328245_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234
LS483309.1\|SQE62146.1\|2313125_2313791_-\|oxidoreductase-ylbE	unknown	unknown	gnl\|CDD\|187554
LS483309.1\|SQE62141.1\|2307932_2308376_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	unknown	unknown	gnl\|CDD\|223854
LS483309.1\|SQE62152.1\|2320114_2320972_-\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|223635
LS483309.1\|SQE62153.1\|2321039_2321822_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
LS483309.1\|SQE62140.1\|2307101_2307812_+\|Purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
LS483309.1\|SQE62145.1\|2311752_2312691_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
LS483309.1\|SQE62144.1\|2311491_2311722_-\|membrane-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE62148.1\|2314264_2315245_+\|Cobalt-zinc-cadmium-resistance-protein	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
LS483309.1\|SQE62151.1\|2317892_2319029_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.91533e-06
LS483309.1\|SQE62147.1\|2313942_2314263_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
LS483309.1\|SQE62154.1\|2322053_2323859_-\|glucosamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
LS483309.1\|SQE62143.1\|2309446_2310820_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
LS483309.1\|SQE62150.1\|2317630_2317834_-\|resolvase-like-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.78732e-14
LS483309.1\|SQE62157.1\|2328256_2328691_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
LS483309.1\|SQE62155.1\|2324539_2326078_+\|PTS-system,-mannitol-specific-IIBC-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
LS483309.1\|SQE62142.1\|2308575_2308989_-\|thiol-disulfide-oxidoreductase	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
LS483309.1\|SQE62159.1\|2330115_2337612_-\|FmtB-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	7.17591e-109
LS483309.1\|SQE62156.1\|2326112_2328245_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
LS483309.1\|SQE62146.1\|2313125_2313791_-\|oxidoreductase-ylbE	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
LS483309.1\|SQE62141.1\|2307932_2308376_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
LS483309.1\|SQE62152.1\|2320114_2320972_-\|Putative-cytosolic-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
LS483309.1\|SQE62153.1\|2321039_2321822_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.88024e-103
LS483309.1\|SQE62140.1\|2307101_2307812_+\|Purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
LS483309.1\|SQE62145.1\|2311752_2312691_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
LS483309.1\|SQE62158.1\|2328690_2329797_+\|Mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0

>LS483309.1|SQE62149.1|2315510_2316602_+|Lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>LS483309.1|SQE62148.1|2314264_2315245_+|Cobalt-zinc-cadmium-resistance-protein
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>LS483309.1|SQE62147.1|2313942_2314263_+|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>LS483309.1|SQE62146.1|2313125_2313791_-|oxidoreductase-ylbE
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>LS483309.1|SQE62145.1|2311752_2312691_-|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>LS483309.1|SQE62144.1|2311491_2311722_-|membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>LS483309.1|SQE62143.1|2309446_2310820_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>LS483309.1|SQE62142.1|2308575_2308989_-|thiol-disulfide-oxidoreductase
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>LS483309.1|SQE62141.1|2307932_2308376_-|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>LS483309.1|SQE62140.1|2307101_2307812_+|Purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>LS483309.1|SQE62150.1|2317630_2317834_-|resolvase-like-protein
MIVYQRKINIDTLKEFGCGCVYSERISGVKRTELVKCLDYLRESDTLVVYQLDRLGRTTKLLIELSQ
>LS483309.1|SQE62151.1|2317892_2319029_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>LS483309.1|SQE62152.1|2320114_2320972_-|Putative-cytosolic-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>LS483309.1|SQE62153.1|2321039_2321822_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMFAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>LS483309.1|SQE62154.1|2322053_2323859_-|glucosamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>LS483309.1|SQE62155.1|2324539_2326078_+|PTS-system,-mannitol-specific-IIBC-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>LS483309.1|SQE62156.1|2326112_2328245_+|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>LS483309.1|SQE62157.1|2328256_2328691_+|PTS-system-mannitol-specific-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>LS483309.1|SQE62158.1|2328690_2329797_+|Mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>LS483309.1|SQE62159.1|2330115_2337612_-|FmtB-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPTAQPAAPANQGQPAVQPANQGGQANPAGGAAQPNTQPANQGGQANPAGGAAQPNTQPAGQGNQADPNNAAQAQPGNQATPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNNSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVKTANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEISKIENITDSTQTKMDAYNEVKQAATARKAQNATVSNATNEEVAEADAAVDAAQKQGLHDIQVVKSKQEVADTKSKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKQAAYTELDTKKQEARTNLDAANTNSDVTTAKDNSIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNAAANNDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDGNNGSTTEEKAAAKQQVQTEKTTADAAIDAAHTNAEVEAAKKAAIAKIEAIQPATTTKDNAKEAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGENSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQVADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATTEEKEAAIQQLATAVTDAKNNITAATDDNGVDQAKDAGKNSIQSTQPATAVKSNAKNDVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALESINNGVDNGDVDDALTQGKAAIDAIQVDATVKPKANQAIEVKAEDTKESIDQSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVNADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPEVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNAEVAELQNVTIPAIEAIVPQNDPDANDTNNGIDNNDATANSNANATPENTGQPNVSETTANGKADASPTTPNNSDAATGETTATSATDDANDKPQANNNSSVDASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNDKVAQPKSENKAKAEKDGSDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKEKMTSTNVSQKDDTATADTNDTQKSVGSAANNKATQNDGANASPATVSNGSNSANQDMLNVTNTDDHQAKTKSAQQGKVNKAKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: LS483309_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_9

2445460-2445653

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of LS483309_9

>merge|LS483309|9|2445460-2445653|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>LS483309|9|2|2445460-2445653|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE62269.1\|2444753_2445104_-\|Transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
LS483309.1\|SQE62278.1\|2452152_2452758_-\|Molybdenum-transport-ATP-binding-protein-modC	unknown	unknown	gnl\|CDD\|226628
LS483309.1\|SQE62279.1\|2452758_2453430_-\|Molybdenum-transport-system-permease-protein-modB	unknown	unknown	gnl\|CDD\|226629
LS483309.1\|SQE62264.1\|2440184_2441450_-\|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis	unknown	unknown	gnl\|CDD\|225224
LS483309.1\|SQE62277.1\|2450978_2451983_-\|Molybdopterin-biosynthesis-MoeB-protein	unknown	unknown	gnl\|CDD\|181084
LS483309.1\|SQE62263.1\|2436900_2440068_-\|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein	unknown	unknown	gnl\|CDD\|223911
LS483309.1\|SQE62270.1\|2445794_2446817_-\|Molybdenum-cofactor-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|274250
LS483309.1\|SQE62262.1\|2436396_2436714_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE62260.1\|2434946_2435855_-\|AEC-family-malonate-efflux-carrier	unknown	unknown	gnl\|CDD\|223751
LS483309.1\|SQE62276.1\|2450441_2450948_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
LS483309.1\|SQE62271.1\|2446836_2447436_-\|molybdopterin-guanine-dinucleotide-biosynthesis-mobA	unknown	unknown	gnl\|CDD\|234725
LS483309.1\|SQE62266.1\|2442081_2442846_-\|glyoxalase-like-domain-protein	unknown	unknown	gnl\|CDD\|379203
LS483309.1\|SQE62272.1\|2447442_2447676_-\|Molybdopterin-converting-factor,-subunit-1	unknown	unknown	gnl\|CDD\|340452
LS483309.1\|SQE62265.1\|2441838_2442090_+\|membrane-protein	unknown	unknown	unknown
LS483309.1\|SQE62261.1\|2435987_2436152_+\|DNA-repair/chromosome-segregation-ATPase	unknown	unknown	unknown
LS483309.1\|SQE62268.1\|2443440_2444652_+\|Major-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|341042
LS483309.1\|SQE62275.1\|2448623_2449883_-\|Molybdopterin-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|238452
LS483309.1\|SQE62267.1\|2443007_2443448_+\|MarR-family-regulatory-protein	unknown	unknown	gnl\|CDD\|197670
LS483309.1\|SQE62274.1\|2448141_2448627_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
LS483309.1\|SQE62273.1\|2447681_2448128_-\|Molybdenum-cofactor-biosynthesis-protein-E	unknown	unknown	gnl\|CDD\|223391

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE62271.1\|2446836_2447436_-\|molybdopterin-guanine-dinucleotide-biosynthesis-mobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
LS483309.1\|SQE62278.1\|2452152_2452758_-\|Molybdenum-transport-ATP-binding-protein-modC	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
LS483309.1\|SQE62279.1\|2452758_2453430_-\|Molybdenum-transport-system-permease-protein-modB	gnl\|CDD\|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	5.00875e-95
LS483309.1\|SQE62264.1\|2440184_2441450_-\|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
LS483309.1\|SQE62277.1\|2450978_2451983_-\|Molybdopterin-biosynthesis-MoeB-protein	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
LS483309.1\|SQE62263.1\|2436900_2440068_-\|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
LS483309.1\|SQE62270.1\|2445794_2446817_-\|Molybdenum-cofactor-biosynthesis-protein-A	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
LS483309.1\|SQE62269.1\|2444753_2445104_-\|Transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
LS483309.1\|SQE62260.1\|2434946_2435855_-\|AEC-family-malonate-efflux-carrier	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	1.24911e-42
LS483309.1\|SQE62266.1\|2442081_2442846_-\|glyoxalase-like-domain-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
LS483309.1\|SQE62272.1\|2447442_2447676_-\|Molybdopterin-converting-factor,-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
LS483309.1\|SQE62268.1\|2443440_2444652_+\|Major-facilitator-family-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
LS483309.1\|SQE62275.1\|2448623_2449883_-\|Molybdopterin-biosynthesis-protein-A	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
LS483309.1\|SQE62267.1\|2443007_2443448_+\|MarR-family-regulatory-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
LS483309.1\|SQE62274.1\|2448141_2448627_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
LS483309.1\|SQE62273.1\|2447681_2448128_-\|Molybdenum-cofactor-biosynthesis-protein-E	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
LS483309.1\|SQE62276.1\|2450441_2450948_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.02752e-64

>LS483309.1|SQE62269.1|2444753_2445104_-|Transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>LS483309.1|SQE62268.1|2443440_2444652_+|Major-facilitator-family-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>LS483309.1|SQE62267.1|2443007_2443448_+|MarR-family-regulatory-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>LS483309.1|SQE62266.1|2442081_2442846_-|glyoxalase-like-domain-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>LS483309.1|SQE62265.1|2441838_2442090_+|membrane-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>LS483309.1|SQE62264.1|2440184_2441450_-|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>LS483309.1|SQE62263.1|2436900_2440068_-|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>LS483309.1|SQE62262.1|2436396_2436714_+|Uncharacterised-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>LS483309.1|SQE62261.1|2435987_2436152_+|DNA-repair/chromosome-segregation-ATPase
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>LS483309.1|SQE62260.1|2434946_2435855_-|AEC-family-malonate-efflux-carrier
MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFVMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVYVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLTFIGMTTNLTIIISIIILYVYQAVFV
>LS483309.1|SQE62270.1|2445794_2446817_-|Molybdenum-cofactor-biosynthesis-protein-A
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>LS483309.1|SQE62271.1|2446836_2447436_-|molybdopterin-guanine-dinucleotide-biosynthesis-mobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>LS483309.1|SQE62272.1|2447442_2447676_-|Molybdopterin-converting-factor,-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>LS483309.1|SQE62273.1|2447681_2448128_-|Molybdenum-cofactor-biosynthesis-protein-E
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>LS483309.1|SQE62274.1|2448141_2448627_-|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>LS483309.1|SQE62275.1|2448623_2449883_-|Molybdopterin-biosynthesis-protein-A
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>LS483309.1|SQE62276.1|2450441_2450948_-|molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>LS483309.1|SQE62277.1|2450978_2451983_-|Molybdopterin-biosynthesis-MoeB-protein
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>LS483309.1|SQE62278.1|2452152_2452758_-|Molybdenum-transport-ATP-binding-protein-modC
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG
>LS483309.1|SQE62279.1|2452758_2453430_-|Molybdenum-transport-system-permease-protein-modB
MPDLTPFWISIRVAVISTIIVTVLGIFISKWLYRRKGSWVKLLESLLILPIVLPPTVLGFILLIIFSPRGPIGQFFANVLHLPVVFTLTGAVIASVIVSFPLMYQHTVQGFRGIDTKMINTARTMGASETKIFLKLILPLAKRSILAGIMMSFARALGEFGATLMVAGYIPNKTNTLPLEIYFLVEQGRENEAWLWVLVLVAFSIVVISTINLLNKDKYKEVD

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Crispr_ID: LS483309_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483309_10

2944794-2944877

Orphan

Consensus_repeat	Method
TTTCGAAATTCTCTGTGTTGGGACCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483309_10

>merge|LS483309|10|2944794-2944877|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCCACACCCTAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>LS483309|10|8|2944794-2944877|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCC	ACACCCTAACTCGCATTGCCTGTAGAATTTCT
TTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
LS483309.1\|SQE62723.1\|2936773_2938654_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
LS483309.1\|SQE62734.1\|2946696_2948574_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	unknown	unknown	gnl\|CDD\|235362
LS483309.1\|SQE62731.1\|2944189_2944543_-\|Permease	unknown	unknown	gnl\|CDD\|288237
LS483309.1\|SQE62727.1\|2940522_2941272_-\|exported-protein	unknown	unknown	gnl\|CDD\|373922
LS483309.1\|SQE62737.1\|2950677_2950773_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
LS483309.1\|SQE62736.1\|2950163_2950511_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
LS483309.1\|SQE62730.1\|2943726_2944122_-\|membrane-protein	unknown	unknown	gnl\|CDD\|288237
LS483309.1\|SQE62729.1\|2942904_2943474_-\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|238045
LS483309.1\|SQE62735.1\|2948640_2950020_-\|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase	unknown	unknown	gnl\|CDD\|235392
LS483309.1\|SQE62722.1\|2936025_2936784_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
LS483309.1\|SQE62728.1\|2941290_2942094_-\|subtilase-family-protease	unknown	unknown	gnl\|CDD\|173803
LS483309.1\|SQE62725.1\|2939554_2939956_+\|transposase-(pseudogene)	unknown	unknown	gnl\|CDD\|225382
LS483309.1\|SQE62724.1\|2938745_2938937_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483309.1\|SQE62732.1\|2945095_2945935_-\|Chromosome-(plasmid)-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|275105
LS483309.1\|SQE62733.1\|2945977_2946697_-\|Ribosomal-RNA-small-subunit-methyltransferase-G	unknown	unknown	gnl\|CDD\|234637
LS483309.1\|SQE62726.1\|2940023_2940521_-\|Uncharacterised-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
LS483309.1\|SQE62723.1\|2936773_2938654_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.91285e-06
LS483309.1\|SQE62736.1\|2950163_2950511_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	6.56083e-51
LS483309.1\|SQE62728.1\|2941290_2942094_-\|subtilase-family-protease	gnl\|CDD\|173803	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins. This group is composed of many different subtilisins: Pro-TK-subtilisin, subtilisin Carlsberg, serine protease Pb92 subtilisin, and BPN subtilisins just to name a few. Pro-TK-subtilisin is a serine protease from the hyperthermophilic archaeon Thermococcus kodakaraensis and consists of a signal peptide, a propeptide, and a mature domain. TK-subtilisin is matured from pro-TK-subtilisin upon autoprocessing and degradation of the propeptide. Unlike other subtilisins though, the folding of the unprocessed form of pro-TK-subtilisin is induced by Ca2+ binding which is almost completed prior to autoprocessing. Ca2+ is required for activity unlike the bacterial subtilisins. The propeptide is not required for folding of the mature domain unlike the bacterial subtilases because of the stability produced from Ca2+ binding. Subtilisin Carlsberg is extremely similar in structure to subtilisin BPN'/Novo thought it has a 30% difference in amino acid sequence. The substrate binding regions are also similar and 2 possible Ca2+ binding sites have been identified recently. Subtilisin Carlsberg possesses the highest commercial importance as a proteolytic additive for detergents. Serine protease Pb92, the serine protease from the alkalophilic Bacillus strain PB92, also contains two calcium ions and the overall folding of the polypeptide chain closely resembles that of the subtilisins. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.02571e-48
LS483309.1\|SQE62731.1\|2944189_2944543_-\|Permease	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.35852e-38
LS483309.1\|SQE62727.1\|2940522_2941272_-\|exported-protein	gnl\|CDD\|373922	pfam15526, Ntox21, Novel toxin 21. Bacterial genomes and plasmids encode a variety of peptide and protein toxins that mediate inter-bacterial competition. Bacteriocins are diffusible proteins that parasitize cell-envelope proteins to enter and kill bacteria. Contact-dependent growth inhibition (CDI) is one mechanism of inter-bacterial competition. Novel Toxin 21 (alternatively 16S rRNA endonuclease CdiA) belongs to a family of prokaryotic polymorphic toxin systems implicated in intra-specific conflicts. This RNase toxin found in bacterial polymorphic toxin systems, is proposed to adopt the BECR (Barnase-EndoU-ColicinE5/D-RelE) fold, with two conserved lysine residues and [DS]xDxxxH, RxG[ST] and RxxD motifs. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 4, type 5 or type 7 secretion systems. This is also referred to as the E. cloacae CdiAC. The CdiAC proteins carry a variety of sequence-diverse C-terminal domains, which represent a collection of distinct toxins. Many CdiA-CT toxins have nuclease activities. In accord with the structural homology, CdiA-CT cleaves 16S rRNA at the same site as colicin E3 and this nuclease activity is responsible for growth inhibition.	3.28374e-23
LS483309.1\|SQE62737.1\|2950677_2950773_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	2.811e-05
LS483309.1\|SQE62730.1\|2943726_2944122_-\|membrane-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	5.93989e-39
LS483309.1\|SQE62729.1\|2942904_2943474_-\|helix-turn-helix-family-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.78153e-16
LS483309.1\|SQE62722.1\|2936025_2936784_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	6.08455e-110
LS483309.1\|SQE62734.1\|2946696_2948574_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
LS483309.1\|SQE62725.1\|2939554_2939956_+\|transposase-(pseudogene)	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.26845e-33
LS483309.1\|SQE62735.1\|2948640_2950020_-\|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
LS483309.1\|SQE62732.1\|2945095_2945935_-\|Chromosome-(plasmid)-partitioning-protein-ParB	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	4.59236e-111
LS483309.1\|SQE62733.1\|2945977_2946697_-\|Ribosomal-RNA-small-subunit-methyltransferase-G	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	1.41411e-95

>LS483309.1|SQE62731.1|2944189_2944543_-|Permease
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>LS483309.1|SQE62730.1|2943726_2944122_-|membrane-protein
MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>LS483309.1|SQE62729.1|2942904_2943474_-|helix-turn-helix-family-protein
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCDLFNVTLDDLVKGTIPFAPDIKAQRSLNLWTYVMLIFMTLAAILTGPLVVYWNWAWGITVIVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISMHLANKFL
>LS483309.1|SQE62728.1|2941290_2942094_-|subtilase-family-protease
MSRNLIHLSIGVAIFIISFSFYLLNQPNNWAWSSLNICINDSKPSNVKVAILDTGINNTRINNNFVTKRYNAINNHNQITTDSNHATQVASIITYGEHKEKLIGISKSVSIYDVKVLDDNLKGDIDNIIKGITWSIKNDVNIIHMSFGFQRYNKELHDAIKNAKNKGIILVAAAGNNMDDYSDYPARFNEVYSITAIDKNNKPFIYAPTKKIDFKAPGVDVYTKGSKDELLTVNGTSFAAAYFTAYLTNNLEFRNDLPHILKEYPIK
>LS483309.1|SQE62727.1|2940522_2941272_-|exported-protein
MKNKIIILFLAIIITFTYGNFAEASVVIKEANINNSNSKINTNKINENIYSKNNRNYIDNNFKSKDLNIESSLEHDLNTDKITVDASLKDNYNNKLDKTYDVKFLRIVNENDFKAEFTDQDTGEKIIYDTNEVKASIAPVVAVLVGFIAKQGLKKAIQKYGKTVVTSMIRTSPQVAAQAAKKLGYSATKHVSHGKKVFKKNSKGRPQYISVDKDGHRGGAWKGASSIKNLGSKKTRSGTYDANLKRIGD
>LS483309.1|SQE62726.1|2940023_2940521_-|Uncharacterised-protein
MIINLETQQIHFDLEHEIPYFQSPEKNRIRLDIDVLNKKQISNIINVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSADEKYVIATIKNIKNKDLIDYSLYIKKGLVEPFIVFYNQENIFYISNAVIDIISVSKDTLGYIKSEFNDHCASPY
>LS483309.1|SQE62725.1|2939554_2939956_+|transposase-(pseudogene)
MIITLRSLGRKATDIENALNSMFSALPSHIFKSITFDCGKEFSNWKTICNCHDISIFFADPSMPAQRGLNEHSNGILRRSGLDKELDFNLVTDDHIISVAQKINHRPRKSLGYRTPLEVFMSFIKDDKLSSLI
>LS483309.1|SQE62724.1|2938745_2938937_+|Uncharacterised-protein
MKFRELVKQSYEDLKNLTVTWYNVIALAIIVIVLSTVTTPIIGIPAGLLGGAYYLKRREEKGK
>LS483309.1|SQE62723.1|2936773_2938654_+|ABC-transporter-permease
MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFIITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTILMLIIAYILILFQSSLFLKRRSILSMMKDSVKTDVTTAKVTVIEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFSKNYYETITVDNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNVINIHLNNDLVVKGTKNETFRVTQEDKDKVYPLNLSFNSPVIEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKIITYDDMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>LS483309.1|SQE62722.1|2936025_2936784_+|ABC-transporter-ATP-binding-protein
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFHKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>LS483309.1|SQE62732.1|2945095_2945935_-|Chromosome-(plasmid)-partitioning-protein-ParB
MKKPFSKLFGLKNKDDIIGHIEENRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFEQDVTQARDEVGKSIQAIQQIGLHVEHKDKDHEDYYEIKIRIYKR
>LS483309.1|SQE62733.1|2945977_2946697_-|Ribosomal-RNA-small-subunit-methyltransferase-G
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNYLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVAKLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>LS483309.1|SQE62734.1|2946696_2948574_-|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>LS483309.1|SQE62735.1|2948640_2950020_-|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>LS483309.1|SQE62736.1|2950163_2950511_-|ribonuclease-P-protein-component
MEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>LS483309.1|SQE62737.1|2950677_2950773_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKMAVKF

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LS483309_5	5.1\|938066\|34\|LS483309\|CRISPRCasFinder	938066-938099	34	LS483309.1	1418226-1418259	0	1.0
LS483309_5	5.1\|938066\|34\|LS483309\|CRISPRCasFinder	938066-938099	34	LS483309.1	1509641-1509674	0	1.0
LS483309_9	9.2\|2445539\|36\|LS483309\|CRT	2445539-2445574	36	LS483309.1	1209994-1210029	0	1.0
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	LS483309.1	857821-857846	1	0.962
LS483309_6	6.1\|986927\|26\|LS483309\|CRT	986927-986952	26	LS483309.1	986871-986896	1	0.962
LS483309_6	6.3\|987041\|26\|LS483309\|CRT	987041-987066	26	LS483309.1	894939-894964	1	0.962
LS483309_6	6.3\|987041\|26\|LS483309\|CRT	987041-987066	26	LS483309.1	2076848-2076873	1	0.962
LS483309_6	6.4\|987097\|53\|LS483309\|CRT	987097-987149	53	LS483309.1	292277-292329	1	0.981
LS483309_6	6.4\|987097\|53\|LS483309\|CRT	987097-987149	53	LS483309.1	2756239-2756291	1	0.981
LS483309_7	7.1\|1210093\|26\|LS483309\|CRISPRCasFinder	1210093-1210118	26	LS483309.1	327815-327840	1	0.962
LS483309_7	7.1\|1210093\|26\|LS483309\|CRISPRCasFinder	1210093-1210118	26	LS483309.1	857877-857902	1	0.962
LS483309_9	9.2\|2445539\|36\|LS483309\|CRT	2445539-2445574	36	LS483309.1	1874934-1874969	1	0.972
LS483309_10	10.1\|2944820\|32\|LS483309\|CRISPRCasFinder	2944820-2944851	32	LS483309.1	895019-895050	1	0.969
LS483309_10	10.1\|2944820\|32\|LS483309\|CRISPRCasFinder	2944820-2944851	32	LS483309.1	895077-895108	1	0.969
LS483309_10	10.1\|2944820\|32\|LS483309\|CRISPRCasFinder	2944820-2944851	32	LS483309.1	1135783-1135814	1	0.969
LS483309_10	10.1\|2944820\|32\|LS483309\|CRISPRCasFinder	2944820-2944851	32	LS483309.1	1509731-1509762	1	0.969
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	LS483309.1	327815-327840	2	0.923
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	LS483309.1	857877-857902	2	0.923
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	LS483309.1	986871-986896	2	0.923
LS483309_6	6.1\|986927\|26\|LS483309\|CRT	986927-986952	26	LS483309.1	857821-857846	2	0.923
LS483309_6	6.3\|987041\|26\|LS483309\|CRT	987041-987066	26	LS483309.1	406080-406105	2	0.923
LS483309_7	7.1\|1210093\|26\|LS483309\|CRISPRCasFinder	1210093-1210118	26	LS483309.1	857821-857846	2	0.923
LS483309_7	7.1\|1210093\|26\|LS483309\|CRISPRCasFinder	1210093-1210118	26	LS483309.1	857933-857958	2	0.923
LS483309_9	9.1\|2445483\|33\|LS483309\|CRT	2445483-2445515	33	LS483309.1	894919-894951	2	0.939
LS483309_9	9.1\|2445483\|33\|LS483309\|CRT	2445483-2445515	33	LS483309.1	1210050-1210082	2	0.939
LS483309_9	9.1\|2445483\|33\|LS483309\|CRT	2445483-2445515	33	LS483309.1	1418181-1418213	2	0.939
LS483309_9	9.1\|2445483\|33\|LS483309\|CRT	2445483-2445515	33	LS483309.1	1509687-1509719	2	0.939
LS483309_9	9.1\|2445483\|33\|LS483309\|CRT	2445483-2445515	33	LS483309.1	2076828-2076860	2	0.939
LS483309_9	9.1\|2445483\|33\|LS483309\|CRT	2445483-2445515	33	LS483309.1	2720704-2720736	2	0.939
LS483309_9	9.2\|2445539\|36\|LS483309\|CRT	2445539-2445574	36	LS483309.1	327940-327975	2	0.944
LS483309_9	9.2\|2445539\|36\|LS483309\|CRT	2445539-2445574	36	LS483309.1	1689697-1689732	2	0.944
LS483309_9	9.2\|2445539\|36\|LS483309\|CRT	2445539-2445574	36	LS483309.1	2087572-2087607	2	0.944
LS483309_9	9.3\|2445598\|33\|LS483309\|CRT	2445598-2445630	33	LS483309.1	894919-894951	2	0.939
LS483309_9	9.3\|2445598\|33\|LS483309\|CRT	2445598-2445630	33	LS483309.1	1210050-1210082	2	0.939
LS483309_9	9.3\|2445598\|33\|LS483309\|CRT	2445598-2445630	33	LS483309.1	1418181-1418213	2	0.939
LS483309_9	9.3\|2445598\|33\|LS483309\|CRT	2445598-2445630	33	LS483309.1	2076828-2076860	2	0.939
LS483309_9	9.3\|2445598\|33\|LS483309\|CRT	2445598-2445630	33	LS483309.1	2720704-2720736	2	0.939

1. spacer 5.1|938066|34|LS483309|CRISPRCasFinder matches to position: 1418226-1418259, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 5.1|938066|34|LS483309|CRISPRCasFinder matches to position: 1509641-1509674, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 9.2|2445539|36|LS483309|CRT matches to position: 1209994-1210029, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttctttttgaaattctcta	Protospacer
************************************

4. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to position: 857821-857846, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ********************

5. spacer 6.1|986927|26|LS483309|CRT matches to position: 986871-986896, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaggctggtgg	Protospacer
***********************.**

6. spacer 6.3|987041|26|LS483309|CRT matches to position: 894939-894964, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

7. spacer 6.3|987041|26|LS483309|CRT matches to position: 2076848-2076873, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

8. spacer 6.4|987097|53|LS483309|CRT matches to position: 292277-292329, mismatch: 1, identity: 0.981

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgcgaaaatattatttctgtcccactcccaa	Protospacer
*********************************.*******************

9. spacer 6.4|987097|53|LS483309|CRT matches to position: 2756239-2756291, mismatch: 1, identity: 0.981

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttacgaaaatatcatttctgtcccactcccaa	Protospacer
***********************.*****************************

10. spacer 7.1|1210093|26|LS483309|CRISPRCasFinder matches to position: 327815-327840, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cgggcccccaacatagaagctggcgg	Protospacer
**** *********************

11. spacer 7.1|1210093|26|LS483309|CRISPRCasFinder matches to position: 857877-857902, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcaggcgg	Protospacer
******************** *****

12. spacer 9.2|2445539|36|LS483309|CRT matches to position: 1874934-1874969, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

13. spacer 10.1|2944820|32|LS483309|CRISPRCasFinder matches to position: 895019-895050, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

14. spacer 10.1|2944820|32|LS483309|CRISPRCasFinder matches to position: 895077-895108, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

15. spacer 10.1|2944820|32|LS483309|CRISPRCasFinder matches to position: 1135783-1135814, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

16. spacer 10.1|2944820|32|LS483309|CRISPRCasFinder matches to position: 1509731-1509762, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

17. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to position: 327815-327840, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttgggggcccg	Protospacer
************.******** ****

18. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to position: 857877-857902, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
***** ******.*************

19. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to position: 986871-986896, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccaccagcctctgtgttggggccccg	Protospacer
**.*****.*****************

20. spacer 6.1|986927|26|LS483309|CRT matches to position: 857821-857846, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*****************.** *****

21. spacer 6.3|987041|26|LS483309|CRT matches to position: 406080-406105, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacaaagaagctgacga	Protospacer
************* ********.***

22. spacer 7.1|1210093|26|LS483309|CRISPRCasFinder matches to position: 857821-857846, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*************.****** *****

23. spacer 7.1|1210093|26|LS483309|CRISPRCasFinder matches to position: 857933-857958, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacataaaagcaggcgg	Protospacer
***************.**** *****

24. spacer 9.1|2445483|33|LS483309|CRT matches to position: 894919-894951, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

25. spacer 9.1|2445483|33|LS483309|CRT matches to position: 1210050-1210082, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

26. spacer 9.1|2445483|33|LS483309|CRT matches to position: 1418181-1418213, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

27. spacer 9.1|2445483|33|LS483309|CRT matches to position: 1509687-1509719, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

28. spacer 9.1|2445483|33|LS483309|CRT matches to position: 2076828-2076860, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

29. spacer 9.1|2445483|33|LS483309|CRT matches to position: 2720704-2720736, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

30. spacer 9.2|2445539|36|LS483309|CRT matches to position: 327940-327975, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

31. spacer 9.2|2445539|36|LS483309|CRT matches to position: 1689697-1689732, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

32. spacer 9.2|2445539|36|LS483309|CRT matches to position: 2087572-2087607, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

33. spacer 9.3|2445598|33|LS483309|CRT matches to position: 894919-894951, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

34. spacer 9.3|2445598|33|LS483309|CRT matches to position: 1210050-1210082, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

35. spacer 9.3|2445598|33|LS483309|CRT matches to position: 1418181-1418213, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

36. spacer 9.3|2445598|33|LS483309|CRT matches to position: 2076828-2076860, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

37. spacer 9.3|2445598|33|LS483309|CRT matches to position: 2720704-2720736, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483309_6	6.4\|987097\|53\|LS483309\|CRT	987097-987149	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
LS483309_4	4.1\|894883\|26\|LS483309\|CRISPRCasFinder	894883-894908	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808
LS483309_6	6.3\|987041\|26\|LS483309\|CRT	987041-987066	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808

1. spacer 6.4|987097|53|LS483309|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgagaaactatcatttctgtcccactccctt	Protospacer
************************ **** *********************

2. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

3. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtctgggcctac	Protospacer
****************. *****.

4. spacer 4.1|894883|26|LS483309|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtttggccctga	Protospacer
***************** ** **. .

5. spacer 6.3|987041|26|LS483309|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcga	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

429270 : 491727

Staphylococcus_phage(43.59%)

transposase,integrase,terminase

attL 431617:431632|attR 482496:482511

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE59711.1\|429270_429462_-	Uncharacterised protein	U3PCX8	Staphylococcus_phage	4.9e-23	80.0
SQE59713.1\|429705_430002_+	30S ribosomalprotein S6p	NA	NA	NA	NA
SQE59716.1\|430022_430526_+	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	3.5e-60	74.1
SQE59717.1\|430577_430820_+	30S ribosomalprotein S18p	NA	NA	NA	NA
SQE59720.1\|431058_431958_-	Abortive infection bacteriophage resistance protein	NA	NA	NA	NA
431617:431632	attL	NA	NA	NA	NA
SQE59722.1\|431959_433174_-	Integrase	Q4ZE80	Staphylococcus_phage	1.7e-222	97.3
SQE59727.1\|433122_433341_-	Uncharacterised protein	NA	NA	NA	NA
SQE59729.1\|433452_434148_-	Xre family transcriptional regulator	NA	NA	NA	NA
SQE59732.1\|434292_434505_+	Ps3 protein 14 family transcriptional regulator	NA	NA	NA	NA
SQE59741.1\|434537_434810_+	pathogenicity island protein	Q4ZE77	Staphylococcus_phage	3.8e-37	88.4
SQE59743.1\|434821_434968_+	hypothetical bovine pathogenicity island protein	NA	NA	NA	NA
SQE59745.1\|434960_435170_+	pathogenicity island protein	Q4ZE76	Staphylococcus_phage	1.1e-31	100.0
SQE59747.1\|435172_435502_+	mobile element-associated protein	Q4ZE75	Staphylococcus_phage	7.6e-48	89.9
SQE59749.1\|435565_436435_+	pathogenicity island protein	A0A1W6JQL5	Staphylococcus_phage	2.0e-156	93.1
SQE59751.1\|436451_437921_+	pathogenicity island protein	A0A1W6JQD6	Staphylococcus_phage	1.7e-280	96.7
SQE59754.1\|438199_438562_+	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
SQE59756.1\|438563_438848_+	pathogenicity island protein	A0A1W6JQE4	Staphylococcus_phage	1.9e-47	95.7
SQE59758.1\|438844_439486_+\|transposase	transposase	Q4ZE67	Staphylococcus_phage	1.5e-108	92.5
SQE59761.1\|440022_440364_+	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	1.9e-57	99.1
SQE59763.1\|440394_441048_+	Uncharacterised protein	Q4ZE82	Staphylococcus_phage	1.3e-115	99.1
SQE59765.1\|441100_441628_+	pathogenicity island protein	Q4ZE87	Staphylococcus_phage	7.8e-87	95.4
SQE59767.1\|441630_441972_+\|transposase	transposase	Q4ZE86	Staphylococcus_phage	8.4e-58	98.2
SQE59769.1\|441968_442538_+\|terminase	putative phage terminase	Q4ZE85	Staphylococcus_phage	1.0e-100	97.9
SQE59770.1\|442966_443485_+	pathogenicity island protein	NA	NA	NA	NA
SQE59772.1\|443481_443910_+	pathogenicity island protein	NA	NA	NA	NA
SQE59775.1\|443896_444676_+	pathogenicity island protein	NA	NA	NA	NA
SQE59777.1\|444855_445140_+	pathogenicity island protein	A0A2H4JAH5	uncultured_Caudovirales_phage	2.4e-26	63.0
SQE59779.1\|446192_447167_-	Abortive infection bacteriophage resistance protein	NA	NA	NA	NA
SQE59781.1\|447169_447460_-\|integrase	integrase-like protein	Q4ZE80	Staphylococcus_phage	5.2e-24	70.5
SQE59784.1\|448076_448688_+	staphylococcal enterotoxin, putative	NA	NA	NA	NA
SQE59787.1\|449056_449425_+	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
SQE59789.1\|449605_450178_+	lipoprotein	NA	NA	NA	NA
SQE59791.1\|450315_450579_-	XRE family transcription regulator, putative	NA	NA	NA	NA
SQE59794.1\|450878_451130_+	transglycosylase associated family protein	NA	NA	NA	NA
SQE59796.1\|451555_452137_+	truncated phosphoglycerate mutase family protein	NA	NA	NA	NA
SQE59798.1\|452202_452589_-	membrane spanning protein	NA	NA	NA	NA
SQE59800.1\|452840_453467_-	lipoprotein	NA	NA	NA	NA
SQE59803.1\|453539_453797_-	Uncharacterised protein	NA	NA	NA	NA
SQE59805.1\|453911_455435_-	Alkyl hydroperoxide reductase protein F	A0A249XZT7	Enterococcus_phage	1.9e-40	33.6
SQE59808.1\|455450_456020_-	Alkyl hydroperoxide reductase protein C	NA	NA	NA	NA
SQE59810.1\|456460_457267_+	Chromate reductase	NA	NA	NA	NA
SQE59813.1\|457347_458736_-	Sodium:dicarboxylate symporter family protein	NA	NA	NA	NA
SQE59815.1\|459712_460669_-	DNA-binding protein	NA	NA	NA	NA
SQE59818.1\|460786_461449_-	Uncharacterised protein	NA	NA	NA	NA
SQE59820.1\|461591_461999_-	transcriptional regulator	NA	NA	NA	NA
SQE59823.1\|462511_463090_+	Xanthine phosphoribosyltransferase	NA	NA	NA	NA
SQE59826.1\|463089_464358_+	Xanthine permease	NA	NA	NA	NA
SQE59828.1\|464395_465862_+	Inosine-5-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
SQE59830.1\|465886_467428_+	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	1.2e-23	32.6
SQE59833.1\|467495_468689_-\|integrase	integrase-like protein	A0A0S2MV79	Bacillus_phage	8.3e-44	34.2
SQE59835.1\|468715_468916_-	Domain of uncharacterised function (DUF3173)	NA	NA	NA	NA
SQE59837.1\|469413_469644_-	Polyribonucleotide nucleotidyltransferase	A0A1S5SEX1	Streptococcus_phage	1.0e-27	78.9
SQE59839.1\|469640_470063_-	Sigma-70 Region 4 protein	A0A1S5SEW0	Streptococcus_phage	7.5e-48	68.6
SQE59841.1\|470593_470947_+	putative HTH-type transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	2.2e-53	89.7
SQE59844.1\|471290_473210_-	tetracycline resistance protein TetM	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.2
SQE59846.1\|473586_474516_-	conjugative transposon-like protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
SQE59849.1\|474532_475555_-	NLP/P60 family lipoprotein	A0A1S5SEZ8	Streptococcus_phage	2.4e-132	75.5
SQE59851.1\|475551_477579_-	Conjugative transposon membrane protein	A0A1S5SF30	Streptococcus_phage	2.3e-195	65.5
SQE59853.1\|477575_480029_-	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	78.8
SQE59856.1\|480012_480408_-	conjugative transposon-like protein	A0A1S5SEX7	Streptococcus_phage	5.9e-47	72.6
SQE59857.1\|480479_481109_-	Uncharacterised protein	NA	NA	NA	NA
SQE59860.1\|481137_481866_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	7.8e-37	39.0
SQE59863.1\|481865_483293_-\|transposase	putative transposase	NA	NA	NA	NA
482496:482511	attR	NA	NA	NA	NA
SQE59864.1\|483376_483505_-	Uncharacterised protein	NA	NA	NA	NA
SQE59866.1\|483560_484061_-	putative antirestriction protein	A0A1S5SF25	Streptococcus_phage	1.7e-54	63.0
SQE59868.1\|484121_484883_-	Protein of uncharacterised function (DUF3644)	NA	NA	NA	NA
SQE59870.1\|484942_485164_-	Conjugative transposon protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
SQE59872.1\|485160_485451_-	Uncharacterised protein	NA	NA	NA	NA
SQE59873.1\|485447_486632_-	replication initiation factor	A0A1S5SEX3	Streptococcus_phage	6.3e-161	68.1
SQE59875.1\|486813_488217_-	Ftsk domain-containing protein	A0A1S5SFB5	Streptococcus_phage	7.5e-177	66.7
SQE59876.1\|488238_489012_-	putative mom-like protein	NA	NA	NA	NA
SQE59878.1\|489021_489399_-	Conjugative transposon protein	A0A1S5SF96	Streptococcus_phage	9.6e-47	76.4
SQE59880.1\|489419_489734_-	putative conjugative transposon protein	A0A1S5SF38	Streptococcus_phage	1.2e-42	77.7
SQE59882.1\|489933_491727_-	putative UvrD/REP helicase	E3T5J8	Cafeteria_roenbergensis_virus	6.9e-26	23.8

DBSCAN-SWA_2

600120 : 607555

Klosneuvirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE60049.1\|600120_601416_+\|tRNA	tRNA(Ile)-lysidine synthetase	A0A1V0SI91	Klosneuvirus	4.8e-13	24.5
SQE60052.1\|601420_601960_+	hypoxanthine-guanine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	6.5e-12	29.8
SQE60054.1\|602216_602921_+	Cell division protein FtsH	R4TQL5	Phaeocystis_globosa_virus	6.5e-12	52.9
SQE60057.1\|602923_604309_+	Cell division protein FtsH	E5EQ50	Micromonas_sp._RCC1109_virus	1.1e-82	47.4
SQE60060.1\|604537_605419_+	Chaperonin (heat shock protein 33)	NA	NA	NA	NA
SQE60063.1\|605597_606530_+	beta-cyano-L-alanine synthase	A0A1X9I5K7	Streptococcus_phage	3.7e-108	65.7
SQE60065.1\|606745_607555_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	8.8e-21	29.0

DBSCAN-SWA_3

826456 : 834276

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE60572.1\|826456_827512_-	Sensor histidine protein kinase SaeS (exoprotein expression protein S)	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
SQE60575.1\|827511_828198_-	Response regulator SaeR	NA	NA	NA	NA
SQE60577.1\|828172_828646_-	DoxX family protein	NA	NA	NA	NA
SQE60580.1\|828987_829428_-	lipoprotein	NA	NA	NA	NA
SQE60583.1\|829707_830292_-	Uncharacterised protein	NA	NA	NA	NA
SQE60585.1\|830390_831104_-	Queuosine Biosynthesis QueE Radical SAM	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
SQE60587.1\|831107_831527_-	6-pyruvoyl-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
SQE60589.1\|831528_832197_-	Queuosine Biosynthesis QueC ATPase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
SQE60592.1\|832547_833141_+	Para-aminobenzoate synthase, amidotransferase component PabAb	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
SQE60594.1\|833124_834276_+	Para-aminobenzoate synthetase component I	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_4

846248 : 861035

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE60613.1\|846248_847307_+	histidinol-phosphate aminotransferase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
SQE60615.1\|847657_848200_+	5'-3'-deoxyribonucleotidase, putative	NA	NA	NA	NA
SQE60618.1\|848879_849797_-	Transcription regulator (contains diacylglycerol kinase catalytic domain)	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
SQE60620.1\|850066_851572_-	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
SQE60680.1\|851912_852413_-	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
SQE60682.1\|852432_853299_-	Integral membrane domain protein	NA	NA	NA	NA
SQE60685.1\|854099_854498_+	Nrdi	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
SQE60687.1\|854460_856566_+	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
SQE60689.1\|856683_857655_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
SQE60691.1\|858320_859334_+	FatD	A0A2H4IY97	uncultured_Caudovirales_phage	2.2e-138	78.0
SQE60693.1\|859320_860277_+	Iron compound ABC uptake transporter permease protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
SQE60695.1\|860273_861035_+	Iron compound ABC uptake transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_5

1111110 : 1119583

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE60998.1\|1111110_1111593_+	AIR carboxylase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
SQE60999.1\|1111579_1112704_+	Phosphoribosylaminoimidazole carboxylase ATPase subunit	NA	NA	NA	NA
SQE61000.1\|1112707_1113412_+	Phosphoribosylaminoimidazole-succinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
SQE61001.1\|1113411_1113675_+	Phosphoribosylformylglycinamidine synthase, PurS subunit	NA	NA	NA	NA
SQE61002.1\|1113676_1114348_+	Phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
SQE61003.1\|1114340_1116530_+	Phosphoribosylformylglycinamidine synthase, synthetase subunit	A6N228	Microbacterium_phage	1.1e-139	39.5
SQE61004.1\|1116508_1117993_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.5e-45	31.5
SQE61005.1\|1117985_1119014_+	Phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
SQE61006.1\|1119016_1119583_+	Phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_6

1661319 : 1669631

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE61497.1\|1661319_1662105_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
SQE61498.1\|1662230_1663121_-	endonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
SQE61499.1\|1663130_1664477_-	ATP-dependent RNA helicase YqfR	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
SQE61500.1\|1664590_1665691_-	NIF3 protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
SQE61501.1\|1665693_1666371_-\|tRNA	Putative tRNA-m1A22 methylase	NA	NA	NA	NA
SQE61502.1\|1666501_1667608_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
SQE61503.1\|1667831_1669631_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_7

1738767 : 1747810

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE61576.1\|1738767_1739286_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
SQE61577.1\|1739307_1741581_-	Single-stranded-DNA-specific exonuclease recJ	A7KV88	Bacillus_phage	1.2e-62	28.8
SQE61578.1\|1741783_1744063_-	Protein-export membrane protein secD / Protein-export membrane protein secF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
SQE61579.1\|1744337_1744598_-	Preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
SQE61580.1\|1744616_1745756_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
SQE61581.1\|1745778_1746804_-\|tRNA	S-adenosylmethionine--tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
SQE61582.1\|1746805_1747810_-	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1879996 : 2007995

147

Staphylococcus_phage(86.03%)

holin,tRNA,capsid,transposase,integrase,head,tail,protease,portal,terminase

attL 1964123:1964141|attR 2008054:2008072

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE61693.1\|1879996_1886557_-	LPXTG-motif cell wall anchor domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1
SQE61694.1\|1886882_1887194_-	Rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
SQE61695.1\|1887215_1889633_-\|tRNA	Leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
SQE61696.1\|1889920_1891102_-	Multidrug resistance protein	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
SQE61697.1\|1891211_1892165_+	Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
SQE61698.1\|1892161_1892725_+	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
SQE61699.1\|1892844_1893246_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
SQE61700.1\|1893765_1893990_-	Mobile element protein	Q9MBP7	Staphylococcus_prophage	4.5e-20	81.8
SQE61701.1\|1893986_1894478_-	Transposase	A0A146ICT8	Staphylococcus_phage	2.4e-74	91.6
SQE61702.1\|1894824_1895652_-	Lysophospholipase; Monoglyceride lipase; putative	NA	NA	NA	NA
SQE61703.1\|1895885_1896887_+	Proline dehydrogenase (Proline oxidase)	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
SQE61704.1\|1897008_1897473_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
SQE61705.1\|1897485_1898667_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.6e-225	99.2
SQE61706.1\|1898677_1899310_-	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
SQE61707.1\|1899316_1900360_-	5-amino-6-(5-phosphoribosylamino)uracil reductase	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.4
SQE61708.1\|1900840_1902343_-	pyridine nucleotide-disulfide oxidoreductase family protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
SQE61709.1\|1902865_1903180_+	arsenical resistance operon repressor 2	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
SQE61710.1\|1903179_1904472_+	arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
SQE61711.1\|1904489_1904885_+	arsenate reductase, putative	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
SQE61712.1\|1905179_1906034_-	peptidoglycan endo-beta-N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
SQE61713.1\|1906309_1906534_-	putative staphylococcal protein	NA	NA	NA	NA
SQE61714.1\|1906732_1907203_+	RNA polymerase sigma factor sigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
SQE61715.1\|1907315_1907759_+	comK family protein	NA	NA	NA	NA
SQE61716.1\|1907745_1908189_-	putative staphylococcal protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
SQE61717.1\|1908484_1909120_+\|protease	CAAX amino terminal protease	NA	NA	NA	NA
SQE61718.1\|1909562_1910276_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
SQE61719.1\|1910535_1910838_+	membrane protein	NA	NA	NA	NA
SQE61720.1\|1911093_1911459_+	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
SQE61721.1\|1911455_1911809_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
SQE61722.1\|1912363_1913188_+\|transposase	transposase	A0ZS58	Staphylococcus_virus	1.7e-125	98.2
SQE61723.1\|1913220_1913829_+\|transposase	putative transposase	A0ZS58	Staphylococcus_virus	1.3e-109	96.0
SQE61724.1\|1913891_1914725_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
SQE61725.1\|1914936_1915845_-	Uncharacterised protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
SQE61726.1\|1915969_1917163_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
SQE61727.1\|1917533_1919126_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
SQE61728.1\|1919261_1919747_-\|transposase	IS605/IS200-like transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
SQE61729.1\|1920121_1920892_-	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	7.3e-142	98.4
SQE61730.1\|1920872_1921352_-	phosphohydrolase	A0A2H4PQM4	Staphylococcus_phage	1.5e-84	98.7
SQE61731.1\|1921411_1921669_+	Putative cytosolic protein	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
SQE61732.1\|1921665_1922667_-	O-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
SQE61733.1\|1922671_1923754_-	O-succinylbenzoic acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.8e-205	97.5
SQE61734.1\|1924307_1924529_-	putative lipoprotein	A0A2H4PQN7	Staphylococcus_phage	4.5e-36	98.6
SQE61735.1\|1925102_1925717_+	endonuclease	A0A2H4PQM8	Staphylococcus_phage	9.5e-36	87.3
SQE61736.1\|1926099_1926792_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	6.1e-63	96.1
SQE61737.1\|1926867_1927506_+	lipoprotein	A0A2H4PQM7	Staphylococcus_phage	4.9e-67	91.2
SQE61738.1\|1927533_1927878_+	Uncharacterised protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
SQE61739.1\|1927975_1928398_+	Uncharacterised protein	NA	NA	NA	NA
SQE61740.1\|1928744_1929386_-	Domain of uncharacterised function (DUF955)	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
SQE61741.1\|1929499_1929685_-	[Genomic island nu Sa beta2]	NA	NA	NA	NA
SQE61742.1\|1929686_1929863_-	Uncharacterised protein	NA	NA	NA	NA
SQE61743.1\|1929873_1930257_-	Uncharacterised protein	NA	NA	NA	NA
SQE61744.1\|1930860_1931004_-\|transposase	transposase family protein, putative	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
SQE61745.1\|1931873_1932251_-	exported protein	NA	NA	NA	NA
SQE61746.1\|1932771_1936884_-	[Genomic island nu Sa beta2]	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
SQE61747.1\|1937733_1938933_-	type I restriction-modification enzyme, S subunit, EcoA family protein	A0A2H4PQP5	Staphylococcus_phage	5.5e-229	99.7
SQE61748.1\|1938925_1940482_-	Type I restriction enzyme EcoprrI M protein	A0A2H4PQP4	Staphylococcus_phage	2.3e-288	99.4
SQE61749.1\|1940844_1941564_-\|protease	Serine protease splD	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
SQE61750.1\|1941714_1942431_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
SQE61751.1\|1942588_1943308_-\|protease	Serine protease splD	A0A2H4PQP9	Staphylococcus_phage	1.3e-129	99.2
SQE61752.1\|1943428_1944148_-\|protease	Serine protease splC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
SQE61753.1\|1944205_1944928_-\|protease	Serine protease splB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
SQE61754.1\|1945052_1945760_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.6e-130	100.0
SQE61755.1\|1945979_1947152_+\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
SQE61756.1\|1948058_1948625_+	probable beta-lactamase	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
SQE61757.1\|1949098_1949797_-	lantibiotic ABC transporter protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
SQE61758.1\|1949793_1950555_-	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family protein	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
SQE61759.1\|1950551_1951244_-	lantibiotic immunity protein F	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
SQE61760.1\|1951266_1952640_-\|protease	epidermin leader peptide processing serine protease EpiP	A0A2H4PQH1	Staphylococcus_phage	1.9e-257	99.8
SQE61761.1\|1952649_1953168_-	lantibiotic modifying enzyme	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
SQE61762.1\|1953183_1954428_-	lanthionine synthetase C-like family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
SQE61763.1\|1954420_1956163_-	Epidermin biosynthesis protein epiB	A0A2H4PQG8	Staphylococcus_phage	4.3e-259	54.0
SQE61764.1\|1956227_1956371_-	lantibiotic gallidermin	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
SQE61765.1\|1957491_1958475_-	Leukotoxin LukD	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
SQE61766.1\|1958476_1959412_-	Leukocidin S subunit lukE	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
SQE61767.1\|1960295_1960751_+	[Genomic island nu Sa beta2]	Q4ZCB9	Staphylococcus_virus	1.7e-61	76.8
SQE61768.1\|1960763_1961501_+	Domain of uncharacterised function DUF1828	A0A2H4PQI0	Staphylococcus_phage	2.5e-115	95.0
SQE61769.1\|1961471_1962644_-\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
1964123:1964141	attL	NA	NA	NA	NA
SQE61770.1\|1964906_1965620_-	N-acetylmuramoyl-L-alanine amidase family protein	Q4ZDC1	Staphylococcus_virus	8.0e-143	99.6
SQE61771.1\|1966069_1966615_-	HNH homing endonuclease	Q4ZA78	Staphylococcus_virus	4.9e-100	100.0
SQE61772.1\|1966644_1967286_-	Phage amidase	Q4ZDC4	Staphylococcus_virus	2.9e-120	95.3
SQE61773.1\|1967266_1967704_-\|holin	holin, phage phi LC3 family	A0A2H4PQP0	Staphylococcus_phage	4.1e-73	100.0
SQE61774.1\|1967759_1968155_-	phi ETA orf 63-like protein	Q4ZBP5	Staphylococcus_phage	2.7e-68	100.0
SQE61775.1\|1968160_1969333_-\|tail	phage tail fiber protein	A0A0N9BAZ1	Staphylococcus_phage	1.1e-197	100.0
SQE61776.1\|1969345_1971220_-	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	Q4ZBP7	Staphylococcus_phage	0.0e+00	100.0
SQE61777.1\|1971356_1971656_-	phage protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
SQE61778.1\|1971696_1971873_-	phage protein	Q8LTH6	Staphylococcus_phage	6.1e-28	100.0
SQE61779.1\|1971873_1972251_-	SLT orf 129-like protein	A9CRC6	Staphylococcus_phage	5.6e-55	100.0
SQE61780.1\|1972250_1974074_-	phiETA ORF57-like protein	B2ZYZ8	Staphylococcus_phage	0.0e+00	99.5
SQE61781.1\|1974073_1975972_-	phage protein	Q4ZBQ2	Staphylococcus_phage	0.0e+00	100.0
SQE61782.1\|1975984_1977868_-	GDSL-like Lipase/Acylhydrolase family protein	A0A0H4ITY6	Staphylococcus_phage	0.0e+00	98.9
SQE61783.1\|1977878_1978814_-\|tail	phage tail protein	R4IH41	Staphylococcus_phage	8.2e-180	100.0
SQE61784.1\|1978828_1981798_-\|tail	putative phage tail protein	Q4ZAG7	Staphylococcus_virus	1.9e-262	99.1
SQE61785.1\|1981800_1982142_-	phage protein	A0A2H4PQL5	Staphylococcus_phage	3.5e-56	100.0
SQE61786.1\|1982162_1982657_-	phage protein	R4IFM1	Staphylococcus_phage	4.3e-87	100.0
SQE61787.1\|1982718_1983279_-	phage protein	A0A0H4ITY2	Staphylococcus_phage	5.9e-101	100.0
SQE61788.1\|1983265_1983703_-	phage protein	A0A0E3T9M9	Staphylococcus_phage	2.1e-77	100.0
SQE61789.1\|1983715_1984129_-	HK97 family phage protein	R4IG77	Staphylococcus_phage	2.0e-77	100.0
SQE61790.1\|1984115_1984451_-\|head,tail	putative phage head-tail adaptor protein	A0A2H4PQL0	Staphylococcus_phage	3.0e-60	100.0
SQE61791.1\|1984443_1984758_-	putative phage DNA-packaging protein	R4IFL8	Staphylococcus_phage	4.0e-54	100.0
SQE61792.1\|1984757_1985084_-	Rho termination factor domain-containing protein	A0A0E3TAL3	Staphylococcus_phage	4.3e-51	100.0
SQE61793.1\|1985100_1985925_-\|capsid	putative phage major capsid protein	R4IH32	Staphylococcus_phage	5.6e-148	100.0
SQE61794.1\|1985945_1986542_-	phage minor structural GP20	R4IG73	Staphylococcus_phage	5.6e-73	100.0
SQE61795.1\|1986646_1986853_-\|tRNA	putative seryl-tRNA synthetase	A0A0N9BB04	Staphylococcus_phage	3.2e-28	100.0
SQE61796.1\|1986854_1987820_-\|head	phage minor head protein	A0A0N7E0U6	Staphylococcus_phage	6.7e-169	96.5
SQE61797.1\|1987776_1989195_-\|portal	SPP1 family phage portal protein	R4IFL5	Staphylococcus_phage	2.3e-274	99.8
SQE61798.1\|1989208_1990417_-\|terminase	phage terminase large subunit	R4IG95	Staphylococcus_phage	6.1e-236	100.0
SQE61799.1\|1990409_1990904_-\|terminase	phage terminase small subunit	R4IH30	Staphylococcus_phage	1.1e-74	100.0
SQE61800.1\|1991255_1991657_-	putative phi PVL-like protein	A0A2H4PQK5	Staphylococcus_phage	5.6e-69	100.0
SQE61801.1\|1991657_1991834_-	transcriptional activator rinb-like protein	Q4ZAX6	Staphylococcus_virus	8.5e-22	98.3
SQE61802.1\|1991823_1992060_-	phage protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
SQE61803.1\|1992084_1992321_-	phage protein	C8CH06	Staphylococcus_phage	1.1e-35	100.0
SQE61804.1\|1992357_1992888_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	C8CH05	Staphylococcus_phage	1.7e-94	100.0
SQE61805.1\|1992880_1993129_-	Phage protein	S4V7K0	Staphylococcus_phage	2.7e-37	98.8
SQE61806.1\|1993121_1993430_-	PV83 orf 27-like protein	R4IFL1	Staphylococcus_phage	4.8e-52	100.0
SQE61807.1\|1993426_1993774_-	yopX family protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
SQE61808.1\|1993770_1994172_-	phage protein	Q4ZAC1	Staphylococcus_virus	1.1e-69	100.0
SQE61809.1\|1994184_1994427_-	phage family protein	Q4ZBD5	Staphylococcus_virus	1.9e-40	98.8
SQE61810.1\|1994430_1994787_-	PVL ORF-50 family protein	A0A2I6PDX2	Staphylococcus_phage	1.1e-60	100.0
SQE61811.1\|1994787_1994973_-	phage protein	A0A068A236	Staphylococcus_phage	1.5e-24	90.2
SQE61812.1\|1994972_1995380_-	phage protein	D2JGK8	Staphylococcus_phage	1.7e-73	100.0
SQE61813.1\|1995389_1995611_-	putative phi ETA-like protein	Q4ZBL4	Staphylococcus_phage	1.7e-35	100.0
SQE61814.1\|1995623_1995785_-	Uncharacterised protein	A0A0H4IU12	Staphylococcus_phage	1.0e-21	100.0
SQE61815.1\|1995778_1996558_-	phage like DNA replication protein dnaC	A7YGR0	Staphylococcus_virus	1.6e-144	99.2
SQE61816.1\|1996567_1997305_-	putative phage replication protein	Q6R839	Staphylococcus_virus	5.6e-99	81.4
SQE61817.1\|1997368_1998226_+	Uncharacterised protein	Q4ZBL8	Staphylococcus_phage	9.5e-159	100.0
SQE61818.1\|1998218_1998335_-	Uncharacterised protein	Q4ZBL9	Staphylococcus_phage	1.3e-10	100.0
SQE61819.1\|1998331_1998703_-	phage protein	A1KX69	Staphylococcus_virus	8.8e-69	99.2
SQE61820.1\|1998753_1999005_-	phage protein	G4KNN9	Staphylococcus_phage	3.8e-39	100.0
SQE61821.1\|1999016_1999460_-	ssDNA-binding protein	A0A2I6PD99	Staphylococcus_phage	3.2e-73	95.9
SQE61822.1\|1999456_2000107_-	ERF superfamily	A0A0F6N3I5	Staphylococcus_phage	4.3e-119	99.5
SQE61823.1\|2000107_2000644_-	bacteriophage Mu Gam-like protein	A0A2I6PD93	Staphylococcus_phage	1.7e-81	100.0
SQE61824.1\|2000656_2000917_-	putative phi PVL-like protein	A0A059T5A3	Staphylococcus_phage	1.2e-43	100.0
SQE61825.1\|2001010_2001331_-	Uncharacterised protein	S4V968	Staphylococcus_phage	4.8e-55	100.0
SQE61826.1\|2001331_2001499_-	phage protein	S4V7J2	Staphylococcus_phage	3.1e-21	94.5
SQE61827.1\|2001511_2001721_-	Uncharacterised protein	A0A2H4PQR1	Staphylococcus_phage	9.7e-33	100.0
SQE61828.1\|2001815_2002016_-	prophage L54a, antirepressor	M9NS32	Staphylococcus_phage	2.9e-26	90.6
SQE61829.1\|2002072_2002675_+	phage protein	B7T096	Staphylococcus_virus	9.8e-102	98.0
SQE61830.1\|2002687_2002828_-	phage protein	A0A0H4ITW0	Staphylococcus_phage	5.5e-16	100.0
SQE61831.1\|2002811_2003594_-	putative phage anti-repressor protein	A0A1W6JPN2	Staphylococcus_phage	6.7e-135	100.0
SQE61832.1\|2003595_2003781_-	Helix-turn-helix	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
SQE61833.1\|2004226_2004709_+	phage protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
SQE61834.1\|2004809_2004989_-	phage protein	A0A0N9BAV3	Staphylococcus_phage	1.7e-25	100.0
SQE61835.1\|2005007_2005238_-	Uncharacterised protein	A0A0N9BAY2	Staphylococcus_phage	9.1e-32	90.7
SQE61836.1\|2005389_2005704_+	helix-turn-helix domain-containing protein	A0A0N9BAW4	Staphylococcus_phage	2.2e-52	99.0
SQE61837.1\|2005716_2006178_+	pathogenicity island protein	A0A0H3U308	Staphylococcus_phage	2.7e-83	98.7
SQE61838.1\|2006195_2006699_+	putative lipoprotein	A9CR44	Staphylococcus_phage	8.3e-46	98.8
SQE61839.1\|2006945_2007995_+\|integrase	putative integrase	A0A2H4JB53	uncultured_Caudovirales_phage	5.2e-183	90.3
2008054:2008072	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2088228 : 2215779

148

Staphylococcus_phage(82.11%)

holin,tRNA,capsid,transposase,head,tail,protease,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE61908.1\|2088228_2089656_-\|tRNA	aspartyl/glutamyl-tRNA amidotransferase subunit B	NA	NA	NA	NA
SQE61909.1\|2089668_2091126_-\|tRNA	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A	NA	NA	NA	NA
SQE61910.1\|2091127_2091430_-\|tRNA	Aspartyl-tRNA(Asn) amidotransferase subunit C; Glutamyl-tRNA(Gln) amidotransferase subunit C	NA	NA	NA	NA
SQE61911.1\|2091796_2093335_+	Sodium/proline symporter	NA	NA	NA	NA
SQE61912.1\|2093423_2094623_-	Lipoprotein (pheromone precursor)	NA	NA	NA	NA
SQE61913.1\|2094635_2096639_-	DNA ligase	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
SQE61914.1\|2096642_2098835_-	ATP-dependent DNA helicase UvrD/PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
SQE61915.1\|2098831_2099524_-	geranylgeranylglyceryl diphosphate synthase	NA	NA	NA	NA
SQE61916.1\|2099695_2099998_-	His repressor	NA	NA	NA	NA
SQE61917.1\|2100106_2100469_-	adenylosuccinate lyase	NA	NA	NA	NA
SQE61918.1\|2100447_2101401_-	adenylosuccinate lyase	NA	NA	NA	NA
SQE61919.1\|2102261_2103428_+	Staphopain A precursor	NA	NA	NA	NA
SQE61920.1\|2103458_2103785_+\|protease	putative cysteine protease inhibitor (Staphostatin A)	NA	NA	NA	NA
SQE61921.1\|2104076_2104250_-	Uncharacterised protein	NA	NA	NA	NA
SQE61922.1\|2104230_2104833_-	Uncharacterized protein conserved in bacteria (DUF2179)	NA	NA	NA	NA
SQE61923.1\|2105103_2105925_-	NH(3)-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.8e-69	52.7
SQE61924.1\|2105917_2107387_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
SQE61925.1\|2107570_2108647_+	nitric-oxide synthase	NA	NA	NA	NA
SQE61926.1\|2108666_2109461_+	ACT domain protein	NA	NA	NA	NA
SQE61927.1\|2109650_2111213_-	sodium-dependent dicarboxylate transporter sdcS	NA	NA	NA	NA
SQE61928.1\|2111417_2112515_-	cell wall surface anchor family protein	U5PWM6	Bacillus_phage	1.9e-47	34.6
SQE61929.1\|2112886_2113447_+	Nicotinamidase	G3MA16	Bacillus_virus	2.0e-32	41.2
SQE61930.1\|2113499_2114429_+	inorganic pyrophosphatase	NA	NA	NA	NA
SQE61931.1\|2114848_2116228_+	Aldehyde dehydrogenase	NA	NA	NA	NA
SQE61932.1\|2116347_2117376_-	6-phosphogluconolactonase	NA	NA	NA	NA
SQE61933.1\|2117645_2118047_+	yolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
SQE61934.1\|2118619_2118793_-	exported protein	NA	NA	NA	NA
SQE61935.1\|2119171_2120284_+	choloylglycine hydrolase	NA	NA	NA	NA
SQE61936.1\|2120340_2121183_-	exported protein	NA	NA	NA	NA
SQE61937.1\|2121179_2121737_-	Predicted membrane protein	NA	NA	NA	NA
SQE61938.1\|2121796_2122321_-	membrane protein	NA	NA	NA	NA
SQE61939.1\|2122441_2123005_+	Thioredoxin	NA	NA	NA	NA
SQE61940.1\|2123070_2123811_-	ABC-2 transporter family protein	NA	NA	NA	NA
SQE61941.1\|2123810_2124683_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
SQE61942.1\|2124679_2125360_-	membrane protein	NA	NA	NA	NA
SQE61943.1\|2125360_2126257_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
SQE61944.1\|2126253_2126634_-	GntR family transcriptional regulator	NA	NA	NA	NA
SQE61945.1\|2126897_2127074_-	membrane protein	NA	NA	NA	NA
SQE61946.1\|2127614_2128901_+	Aspartate aminotransferase	NA	NA	NA	NA
SQE61947.1\|2129224_2129515_-	truncated map-w protein; extracellular adherence protein of broad specificity Eap/Map	NA	NA	NA	NA
SQE61948.1\|2129525_2131280_-	MHC class II analog (pseudogene)	NA	NA	NA	NA
SQE61949.1\|2131665_2131851_+	beta-hemolysin	A0A1P8L6A7	Staphylococcus_phage	5.6e-24	100.0
SQE61950.1\|2133040_2133391_-	Involved in expression of fibrinogen binding protein, phage associated	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
SQE61951.1\|2134049_2134541_-	Staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
SQE61952.1\|2134731_2135487_-	Autolysin	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
SQE61953.1\|2135498_2135753_-\|holin	Phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
SQE61954.1\|2136290_2136521_-	phage protein	D2JLG2	Staphylococcus_phage	1.2e-31	100.0
SQE61955.1\|2136644_2136932_-	phage protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
SQE61956.1\|2136978_2137131_-	phage protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
SQE61957.1\|2137120_2140906_-	phage minor structural protein	C8CH32	Staphylococcus_phage	0.0e+00	99.8
SQE61958.1\|2140921_2142406_-	bacteriophage protein	A0A1W6JPN0	Staphylococcus_phage	2.0e-297	100.0
SQE61959.1\|2142402_2146932_-\|tail	TP901 family phage tail tape measure protein	A0A1W6JPL0	Staphylococcus_phage	0.0e+00	100.0
SQE61960.1\|2146988_2147126_-	phage protein	A0A1W6JPS1	Staphylococcus_phage	3.4e-18	100.0
SQE61961.1\|2147176_2147527_-	phage protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
SQE61962.1\|2147843_2148485_-\|tail	phage major tail protein	C8CH27	Staphylococcus_phage	2.5e-119	100.0
SQE61963.1\|2148485_2148893_-	putative bacteriophage protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
SQE61964.1\|2148889_2149294_-	phage protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-69	100.0
SQE61965.1\|2149290_2149653_-\|head,tail	phage head-tail adaptor	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
SQE61966.1\|2149636_2149921_-	Gp6 protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
SQE61967.1\|2149910_2150195_-\|terminase	phage terminase small subunit	A0A1W6JPL8	Staphylococcus_phage	2.3e-45	100.0
SQE61968.1\|2150214_2151435_-\|capsid	Phage major capsid protein	A0A075LYD8	Staphylococcus_phage	7.8e-231	100.0
SQE61969.1\|2151382_2152120_-	ATP-dependent endopeptidase clp proteolytic subunit	A0A1W6JPK0	Staphylococcus_phage	2.3e-129	99.6
SQE61970.1\|2152103_2153267_-	Portal protein, phage associated	A0A1W6JPQ9	Staphylococcus_phage	1.8e-216	100.0
SQE61971.1\|2153282_2154944_-\|terminase	Phage terminase large subunit	Q8LTH3	Staphylococcus_phage	0.0e+00	100.0
SQE61972.1\|2154940_2155285_-	phage protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
SQE61973.1\|2155415_2155715_-	phage-associated homing endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
SQE61974.1\|2155946_2156363_-	phage transcriptional regulator	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
SQE61975.1\|2156410_2156821_-	putative phi PVL-like protein	C8CH13	Staphylococcus_phage	2.3e-70	100.0
SQE61976.1\|2156927_2157074_-	phage protein	Q4ZBJ8	Staphylococcus_phage	7.5e-16	100.0
SQE61977.1\|2157074_2157440_-	phage protein	Q4ZBJ9	Staphylococcus_phage	3.6e-59	100.0
SQE61978.1\|2157440_2157614_-	phage transcriptional activator RinB	C8CH09	Staphylococcus_phage	2.9e-22	100.0
SQE61979.1\|2157610_2158000_-	phage protein	C8CH08	Staphylococcus_phage	3.1e-64	100.0
SQE61980.1\|2157989_2158226_-	phage protein	A7TWB3	Staphylococcus_phage	7.6e-34	93.6
SQE61981.1\|2158250_2158487_-	phage protein	C8CH06	Staphylococcus_phage	4.5e-34	97.4
SQE61982.1\|2158523_2159060_-	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	2.1e-95	100.0
SQE61983.1\|2159052_2159301_-	Phage protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
SQE61984.1\|2159293_2159602_-	PV83 orf 27-like protein	C8CH03	Staphylococcus_phage	9.6e-53	100.0
SQE61985.1\|2159598_2159946_-	yopX family protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
SQE61986.1\|2159942_2160344_-	phage protein	C8CH01	Staphylococcus_phage	3.3e-69	100.0
SQE61987.1\|2160356_2160599_-	phage family protein	Q4ZDP7	Staphylococcus_virus	8.6e-41	98.8
SQE61988.1\|2160604_2160859_-	phage protein	D2JGL1	Staphylococcus_phage	1.3e-42	100.0
SQE61989.1\|2160858_2161131_-	PVL ORF-50-like family	D2JGL0	Staphylococcus_phage	4.2e-44	100.0
SQE61990.1\|2161219_2161405_-	Protein of uncharacterised function (DUF3113)	D2JGK9	Staphylococcus_phage	7.0e-27	100.0
SQE61991.1\|2161404_2161812_-	phage protein	D2JGK8	Staphylococcus_phage	1.7e-73	100.0
SQE61992.1\|2161821_2162043_-	putative phi ETA-like protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
SQE61993.1\|2162045_2162261_-	hypothetical phage-related protein	C8CGZ4	Staphylococcus_phage	3.7e-35	100.0
SQE61994.1\|2162257_2163499_-	prophage L54a, replicative DNA helicase	A9CR70	Staphylococcus_phage	3.3e-229	99.8
SQE61995.1\|2163495_2163852_-	phage protein	M9NS37	Staphylococcus_phage	8.2e-64	100.0
SQE61996.1\|2163851_2164646_-	phi PV83 orf 20-like protein	Q8SDW2	Staphylococcus_phage	3.9e-106	98.5
SQE61997.1\|2164617_2165313_-	phage protein	Q9MBS0	Staphylococcus_prophage	8.9e-131	96.5
SQE61998.1\|2165326_2165755_-	Single-stranded DNA-binding protein, phage associated	B2ZYV4	Staphylococcus_phage	3.9e-60	100.0
SQE61999.1\|2165754_2166378_-	putative phage topoisomerase	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
SQE62000.1\|2166370_2166592_-	phage protein	A7TWM6	Staphylococcus_phage	3.2e-34	100.0
SQE62001.1\|2166601_2166862_-	phage protein	Q4ZDA1	Staphylococcus_virus	1.2e-43	100.0
SQE62002.1\|2166958_2167120_-	phage protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
SQE62003.1\|2167116_2167437_-	Uncharacterized protein conserved in bacteria	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
SQE62004.1\|2167569_2168127_+	phage protein	A0A2I6PDF5	Staphylococcus_phage	1.1e-99	100.0
SQE62005.1\|2168141_2168282_-	phage protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
SQE62006.1\|2168312_2168507_-	Phage protein	A0A1X9H0A2	Staphylococcus_phage	1.5e-19	100.0
SQE62007.1\|2168523_2169276_-	antirepressor	A0A1X9H0A0	Staphylococcus_phage	8.7e-140	100.0
SQE62008.1\|2169332_2169872_+	putative phi PVL-like protein	A7TW92	Staphylococcus_phage	1.5e-96	100.0
SQE62009.1\|2169895_2170156_-	putative phi PVL-like protein	A0A2I6PDT7	Staphylococcus_phage	3.5e-40	100.0
SQE62010.1\|2170168_2170918_-	putative phage anti-repressor protein	A0A1W6JPN2	Staphylococcus_phage	2.0e-136	100.0
SQE62011.1\|2170974_2171184_+	Uncharacterised protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
SQE62012.1\|2171176_2171317_-	phage protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
SQE62013.1\|2171331_2171775_-	hypothetical phage-related protein	W5R971	Staphylococcus_phage	1.5e-75	100.0
SQE62014.1\|2171787_2172030_-	phage DNA-binding protein	A0A1X9H035	Staphylococcus_phage	3.6e-39	98.8
SQE62015.1\|2172193_2172910_+	putative phage repressor protein	A0A1X9H038	Staphylococcus_phage	1.6e-130	99.6
SQE62016.1\|2172921_2173077_+	phage protein	A0A2I6PDR9	Staphylococcus_phage	6.3e-21	100.0
SQE62017.1\|2173063_2173249_+	phage protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
SQE62018.1\|2173448_2173616_+	Putative cytosolic protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
SQE62019.1\|2173755_2174295_+	PemK-like growth inhibitor protein	U5U4R0	Staphylococcus_phage	9.0e-14	33.1
SQE62020.1\|2174467_2175505_+	DNA integration/recombination/inversion protein	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
SQE62021.1\|2175561_2176386_+	phospholipase C	A0A1P8L6H7	Staphylococcus_phage	6.8e-162	100.0
SQE62022.1\|2176623_2177640_-	gamma-hemolysin component B	A0A2I6PER8	Staphylococcus_phage	1.1e-25	29.0
SQE62023.1\|2177661_2178717_-	Leukocidin S subunit	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
SQE62024.1\|2179056_2180229_+\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
SQE62025.1\|2180483_2181707_+	succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
SQE62026.1\|2182078_2182924_-	tetracenomycin polyketide synthesis O-methyltransferase TcmP	NA	NA	NA	NA
SQE62027.1\|2182985_2183897_-	ferric hydroxamate receptor 1	NA	NA	NA	NA
SQE62028.1\|2183952_2185125_-\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
SQE62029.1\|2185389_2186697_+	Na+-transporting ATP synthase	NA	NA	NA	NA
SQE62030.1\|2187549_2187993_-	GCN5-related N-acetyltransferase (GNAT)	NA	NA	NA	NA
SQE62031.1\|2188157_2188499_-	Uncharacterised protein	NA	NA	NA	NA
SQE62032.1\|2188852_2189443_-\|terminase	putative phage terminase	Q4ZE85	Staphylococcus_phage	1.1e-97	95.8
SQE62033.1\|2190353_2191970_-	heat shock protein 60 family chaperone GroEL	A0A240F779	uncultured_virus	1.2e-157	54.7
SQE62034.1\|2192045_2192330_-	Heat shock protein 60 family co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
SQE62035.1\|2192504_2193248_+	abortive infection protein	NA	NA	NA	NA
SQE62036.1\|2193272_2194532_-	membrane anchored protein	NA	NA	NA	NA
SQE62037.1\|2194728_2195355_+	nitroreductase family protein	NA	NA	NA	NA
SQE62038.1\|2195715_2196501_+	Aliphatic amidase amiE	NA	NA	NA	NA
SQE62039.1\|2197413_2198037_+	accessory gene regulator protein B AGRB	NA	NA	NA	NA
SQE62040.1\|2198033_2198174_+	Regulator protein agrD	NA	NA	NA	NA
SQE62041.1\|2198198_2199491_+	Regulator protein agrC	NA	NA	NA	NA
SQE62042.1\|2199509_2199998_+	accessory gene regulator protein A	NA	NA	NA	NA
SQE62043.1\|2200593_2201553_-	Fructokinase	NA	NA	NA	NA
SQE62044.1\|2201549_2203034_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	3.0e-19	25.6
SQE62045.1\|2203182_2204133_-	Sucrose operon repressor ScrR, LacI family	NA	NA	NA	NA
SQE62046.1\|2204315_2205512_-	ammonium transporter family protein	H8ZJB2	Ostreococcus_tauri_virus	2.4e-38	31.1
SQE62047.1\|2205615_2206788_+\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
SQE62048.1\|2207104_2207329_-	transcriptional regulator	NA	NA	NA	NA
SQE62049.1\|2207388_2208468_-	putative transport system permease protein	NA	NA	NA	NA
SQE62050.1\|2208771_2209407_-	Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	NA	NA	NA	NA
SQE62051.1\|2209659_2211588_+	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	5.4e-53	30.4
SQE62052.1\|2211949_2213560_+	MutS-related protein, family 1	A0A0N9R0S5	Chrysochromulina_ericina_virus	3.3e-19	26.9
SQE62053.1\|2213661_2214687_-\|protease	glycoprotease	A0A0R6PI74	Moraxella_phage	6.9e-63	40.9
SQE62054.1\|2214679_2215144_-	Ribosomal-protein-S18p-alanine acetyltransferase	NA	NA	NA	NA
SQE62055.1\|2215116_2215779_-\|protease	Inactive protein of metal-dependent protease family, putative molecular chaperone	NA	NA	NA	NA

DBSCAN-SWA_10

2630213 : 2682685

Bacillus_virus(18.18%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE62445.1\|2630213_2630909_-\|holin	putative glycine betaine/carnitine/choline transport system permease protein	NA	NA	NA	NA
SQE62446.1\|2630908_2631850_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, substrate-binding protein OpuCC	NA	NA	NA	NA
SQE62447.1\|2631866_2632502_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCB	G3M9Y4	Bacillus_virus	9.0e-05	26.2
SQE62448.1\|2632498_2633725_-\|holin	glycine betaine/carnitine/choline ABC transporter, ATP-binding protein, putative	Q6GZ03	Mycoplasma_phage	6.6e-20	50.5
SQE62449.1\|2634394_2634994_-	molecular chaperone GroEL	NA	NA	NA	NA
SQE62450.1\|2635173_2636811_+	Amino acid permease	NA	NA	NA	NA
SQE62451.1\|2637418_2638771_+	Carboxylesterase type B	A0A0B5J865	Pandoravirus	2.5e-12	34.2
SQE62452.1\|2638832_2640020_-	chloramphenicol resistance protein	NA	NA	NA	NA
SQE62453.1\|2640415_2641192_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
SQE62454.1\|2641184_2641847_-	Methionine ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.5e-22	32.2
SQE62455.1\|2642094_2643171_-	endoglucanase M	NA	NA	NA	NA
SQE62456.1\|2643525_2643792_-	addiction module toxin	NA	NA	NA	NA
SQE62457.1\|2643791_2644049_-	prevent-host-death family protein	NA	NA	NA	NA
SQE62458.1\|2644407_2644863_+	lipoprotein	NA	NA	NA	NA
SQE62459.1\|2645030_2646608_-	Ferredoxin-dependent glutamate synthase	NA	NA	NA	NA
SQE62460.1\|2646802_2647552_+	membrane protein	NA	NA	NA	NA
SQE62461.1\|2647775_2648969_-	Antibiotic resistance protein	NA	NA	NA	NA
SQE62462.1\|2648980_2649730_-	nickel transport ATP-binding protein	G3M9Y6	Bacillus_virus	4.0e-20	30.8
SQE62463.1\|2649722_2650538_-	Oligopeptide transporter putative ATPase domain protein	G9BWD6	Planktothrix_phage	1.8e-13	30.3
SQE62464.1\|2650534_2651404_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
SQE62465.1\|2651400_2652336_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
SQE62466.1\|2652348_2653947_-	Oligopeptide transporter putative substrate binding domain protein	NA	NA	NA	NA
SQE62467.1\|2654089_2655391_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
SQE62468.1\|2655383_2656202_-	nicotianamine synthase	NA	NA	NA	NA
SQE62469.1\|2656212_2657034_-	Putative Similar to diaminopimelate epimerase	NA	NA	NA	NA
SQE62470.1\|2657900_2658266_-	Uncharacterised protein	NA	NA	NA	NA
SQE62471.1\|2658528_2659248_-	Glutamate dehydrogenase	A0A0G2Y8L6	Acanthamoeba_polyphaga_mimivirus	2.9e-07	36.5
SQE62472.1\|2659579_2661118_+	aminobenzoyl-glutamate transport protein	NA	NA	NA	NA
SQE62473.1\|2661229_2661652_-\|transposase	transposase	NA	NA	NA	NA
SQE62474.1\|2662103_2662523_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
SQE62475.1\|2662540_2662960_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
SQE62476.1\|2663226_2663649_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
SQE62477.1\|2663899_2664595_-	Short-chain alcohol dehydrogenase	W8CYX9	Bacillus_phage	8.6e-09	36.5
SQE62478.1\|2664883_2665165_+	IraB protein	NA	NA	NA	NA
SQE62479.1\|2665424_2665616_-	Uncharacterised protein	NA	NA	NA	NA
SQE62480.1\|2666097_2666190_-	Uncharacterised protein	NA	NA	NA	NA
SQE62481.1\|2666176_2666971_-	lipoprotein	NA	NA	NA	NA
SQE62482.1\|2667082_2667859_-	putative lipoprotein	NA	NA	NA	NA
SQE62483.1\|2668161_2671023_-	DNA/RNA helicase of DEAD/DEAH box family	Q5YA94	Bacillus_phage	2.4e-28	27.9
SQE62484.1\|2671024_2671417_-	7,8-dihydro-8-oxoguanine-triphosphatase	NA	NA	NA	NA
SQE62485.1\|2671704_2673342_+	Phosphoglucomutase	A0A1X9I671	Streptococcus_phage	1.7e-95	38.1
SQE62486.1\|2673625_2673892_+	exported protein	NA	NA	NA	NA
SQE62487.1\|2674035_2674344_+	membrane protein	NA	NA	NA	NA
SQE62488.1\|2674451_2674622_-	Uncharacterised protein	NA	NA	NA	NA
SQE62489.1\|2674665_2675859_-	Macrolide-efflux protein	NA	NA	NA	NA
SQE62490.1\|2676242_2676833_-	Virulence-associated cell-wall-anchored protein SasG (LPXTG motif), binding to squamous nasal epithelial cells	NA	NA	NA	NA
SQE62491.1\|2679309_2680128_-	cell wall surface anchor family protein	NA	NA	NA	NA
SQE62492.1\|2680364_2680742_-	surface protein G1	NA	NA	NA	NA
SQE62493.1\|2681047_2681368_-	Transcriptional regulator SarT (Staphylococcal accessory regulator T)	NA	NA	NA	NA
SQE62494.1\|2681512_2682685_+\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0

DBSCAN-SWA_11

2736200 : 2792116

Staphylococcus_phage(25.0%)

transposase,integrase,lysis,protease

attL 2781047:2781063|attR 2797163:2797179

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQE62543.1\|2736200_2737373_-\|transposase	IS256-like transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
SQE62544.1\|2737712_2737970_-	Uncharacterised protein	NA	NA	NA	NA
SQE62545.1\|2738548_2739826_-	3-hydroxy-3-methylglutaryl-coenzyme A reductase	NA	NA	NA	NA
SQE62546.1\|2740079_2741246_+	Hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
SQE62547.1\|2741415_2741937_-	methylated-DNA--protein-cysteine methyltransferase	M1PFU9	Streptococcus_phage	2.0e-26	41.1
SQE62548.1\|2742346_2744452_+\|protease	putative ATP-dependent protease ATP-binding subunit ClpL	H6X3M6	Enterobacteria_phage	3.1e-118	38.5
SQE62549.1\|2744520_2744691_-	virus attachment p12 family protein	NA	NA	NA	NA
SQE62550.1\|2744703_2745975_-	ferrous iron transport protein B	NA	NA	NA	NA
SQE62551.1\|2745923_2746697_-	Ferrous iron transport protein B	NA	NA	NA	NA
SQE62552.1\|2746708_2746936_-	feoA domain protein	NA	NA	NA	NA
SQE62553.1\|2747151_2749620_-	Putative antibiotic transport-associated protein	NA	NA	NA	NA
SQE62554.1\|2749785_2750334_+	TetR family regulatory protein	NA	NA	NA	NA
SQE62555.1\|2750689_2752234_-	Delta-1-pyrroline-5-carboxylate dehydrogenase	NA	NA	NA	NA
SQE62556.1\|2752423_2753023_-	O-acetyltransferase (cell wall biosynthesis)	NA	NA	NA	NA
SQE62557.1\|2753261_2753453_+	exported protein	NA	NA	NA	NA
SQE62558.1\|2753692_2755336_+	Copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.4e-81	40.6
SQE62559.1\|2755421_2756102_+	Copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.8e-36	44.1
SQE62560.1\|2756646_2756853_+	CopZ	NA	NA	NA	NA
SQE62561.1\|2756942_2757971_-	D-lactate dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	3.6e-35	30.2
SQE62562.1\|2757963_2759118_-	aspartate aminotransferase	NA	NA	NA	NA
SQE62563.1\|2759544_2761053_-	Dehydrosqualene desaturase (Diapophytoene desaturase) (4,4-diapophytoene desaturase)	NA	NA	NA	NA
SQE62564.1\|2761064_2761928_-	dehydrosqualene synthase	NA	NA	NA	NA
SQE62565.1\|2761964_2763092_-	Hpnb	NA	NA	NA	NA
SQE62566.1\|2763097_2764591_-	Phytoene desaturase, neurosporene or lycopene producing / 4,4-diapolycopene oxidase	NA	NA	NA	NA
SQE62567.1\|2764583_2765081_-	Glycosyl-4,4-diaponeurosporenoate acyltransferase precursor	NA	NA	NA	NA
SQE62568.1\|2765252_2766020_-	Secretory antigen precursor SsaA	NA	NA	NA	NA
SQE62569.1\|2766380_2768192_-	O-acetyltransferase oatA	A0A1R3Y5Q6	Salmonella_virus	1.3e-35	31.5
SQE62570.1\|2768877_2769579_-	Immunodominant staphylococcal antigen A precursor	Q4Z8Z7	Staphylococcus_phage	2.1e-39	46.8
SQE62571.1\|2770186_2771242_-	membrane spanning protein	NA	NA	NA	NA
SQE62572.1\|2771634_2772222_+	TetR family transcriptional regulator	NA	NA	NA	NA
SQE62573.1\|2772599_2772920_+	Uncharacterised protein	NA	NA	NA	NA
SQE62574.1\|2773139_2773370_+	putative DUF896-containing protein	NA	NA	NA	NA
SQE62575.1\|2773532_2773910_-	glyoxalase	NA	NA	NA	NA
SQE62576.1\|2773926_2774748_-	NAD dependent epimerase/dehydratase family protein	NA	NA	NA	NA
SQE62577.1\|2774766_2775066_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
SQE62578.1\|2775196_2775754_+	Transcriptional regulator, TetR family	NA	NA	NA	NA
SQE62579.1\|2775746_2776451_+	short-chain dehydrogenase	NA	NA	NA	NA
SQE62580.1\|2776548_2777559_+	5-carboxyvanillic acid decarboxylase	NA	NA	NA	NA
SQE62581.1\|2777578_2778409_+	Esterase/Lipase	NA	NA	NA	NA
SQE62582.1\|2778555_2779446_-	Putative GTPases (G3E family)	NA	NA	NA	NA
SQE62583.1\|2779545_2780886_-	ferrous iron transporter protein B	NA	NA	NA	NA
SQE62584.1\|2780879_2781986_-	monooxygenase	NA	NA	NA	NA
2781047:2781063	attL	NA	NA	NA	NA
SQE62585.1\|2782380_2782734_-\|transposase	putative transposase	Q9MBM9	Staphylococcus_prophage	8.8e-18	46.6
SQE62586.1\|2783017_2783833_-	putative ATP-binding protein	NA	NA	NA	NA
SQE62587.1\|2783825_2785268_-\|integrase	integrase core domain-containing protein	NA	NA	NA	NA
SQE62588.1\|2785239_2785833_-	DNA-invertase hin	A0A0A7NPV4	Enterobacteria_phage	1.1e-41	51.1
SQE62589.1\|2786096_2786477_-	penicillinase repressor	NA	NA	NA	NA
SQE62590.1\|2786466_2788224_-	regulatory protein BlaR1	NA	NA	NA	NA
SQE62591.1\|2788330_2789176_+	beta-lactamase	A0A1B0VBP7	Salmonella_phage	1.5e-31	34.0
SQE62592.1\|2789436_2789952_-\|transposase	putative transposase	NA	NA	NA	NA
SQE62593.1\|2790060_2790417_-	lipoprotein	NA	NA	NA	NA
SQE62594.1\|2790472_2791063_-	transposon-related protein	NA	NA	NA	NA
SQE62595.1\|2791069_2792116_-\|lysis	putative cell wall lysis protein	A0A1X9I9L1	Staphylococcus_phage	8.1e-19	36.9
2797163:2797179	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: LS483309.1|SQE62568.1|2765252_2766020_-|Secretory-antigen-precursor-SsaA

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LS483309.1|SQE62568.1|2765252_2766020_-|Secretory-antigen-precursor-SsaA

2765252_2766020_-

255 aa aa

2736200-2792116

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
LS483309_6	Orphan	6.4\|987097\|53\|LS483309\|CRT	987097-987149	53	2756291-2756239	1

1. spacer 6.4|987097|53|LS483309|CRT matches to LS483309 position: 2756291-2756239, mismatch: 1

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttacgaaaatatcatttctgtcccactcccaa	Protospacer
***********************.*****************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LS483309

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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