CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483331	Streptococcus pyogenes strain NCTC12057 genome assembly, chromosome: 1	2 crisprs	DinG,csm6,RT,cas3,DEDDh,csa3	0	1	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483331_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483331_1

798809-799027

Orphan

II-A

Consensus_repeat	Method
TGTTTTGAATGGTCCCAAAAC	CRT

3 spacers

The CRISPR arrays of LS483331_1

>merge|LS483331|1|798809-799027|CRT
TGTTTTGAATGGTCCCAAAACGATTAGCTCAAGCATGCCTTTATAAATGTCGTTTTAGAGCTATGTTGTGTTGAATGGTCCCAAAACCAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGTTGTTTTGAATGGTCCCAAAACGCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGCTGTTTTGAATGGTCTCCATTC

>LS483331|1|1|798809-799027|CRT
TGTTTTGAATGGTCCCAAAAC	GATTAGCTCAAGCATGCCTTTATAAATGTCGTTTTAGAGCTATGT
TGTGTTGAATGGTCCCAAAAC	CAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGT
TGTTTTGAATGGTCCCAAAAC	GCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGC
TGTTTTGAATGGTCTCCATTC

Protein	Signature genes	Signature genes Name	Protein_function
LS483331.1\|SQF09598.1\|794648_795290_+\|acetyltransferase-GNAT-Family	unknown	unknown	unknown
LS483331.1\|SQF09607.1\|801759_803199_+\|Collagen-like-surface-protein	unknown	unknown	gnl\|CDD\|237171
LS483331.1\|SQF09595.1\|792159_793116_+\|hypothetical-membrane-associated-protein	unknown	unknown	gnl\|CDD\|227193
LS483331.1\|SQF09622.1\|807906_809556_+\|two-component-sensor-kinase	unknown	unknown	gnl\|CDD\|225519
LS483331.1\|SQF09616.1\|805629_806121_+\|PTS-system-mannose/fructose-family-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
LS483331.1\|SQF09591.1\|789861_791199_-\|UDP-N-acetylmuramoylalanyl-D-glutamate-2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|223840
LS483331.1\|SQF09589.1\|789070_789862_-\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|225974
LS483331.1\|SQF09606.1\|799670_801503_+\|GTP-binding-protein-LepA	unknown	unknown	gnl\|CDD\|235462
LS483331.1\|SQF09600.1\|796492_797245_+\|oleoyl-[acyl-carrier-protein]-hydrolase	unknown	unknown	gnl\|CDD\|226401
LS483331.1\|SQF09603.1\|799139_799337_+\|nucleoside-diphosphate-kinase-protein-Ndk	unknown	unknown	gnl\|CDD\|179085
LS483331.1\|SQF09620.1\|806943_807771_+\|phospotransferase-system-(PTS),-enzyme-II-component-D	unknown	unknown	gnl\|CDD\|226239
LS483331.1\|SQF09618.1\|806137_806947_+\|PTS-system,-mannose-specific-IIC-component	unknown	unknown	gnl\|CDD\|226238
LS483331.1\|SQF09596.1\|793169_794525_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
LS483331.1\|SQF09593.1\|791311_792163_+\|disA-bacterial-checkpoint-controller-nucleotide-binding-family-protein	unknown	unknown	gnl\|CDD\|224539
LS483331.1\|SQF09601.1\|797244_798009_+\|haloacid-dehalogenase-like-hydrolase	unknown	unknown	gnl\|CDD\|319832
LS483331.1\|SQF09610.1\|803384_803822_+\|methionine-sulfoxide-reductase-B	unknown	unknown	gnl\|CDD\|234692
LS483331.1\|SQF09614.1\|805177_805603_+\|PTS-system-mannose-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
LS483331.1\|SQF09612.1\|803951_804971_+\|hypothetical-membrane-spanning-protein	unknown	unknown	gnl\|CDD\|225411
LS483331.1\|SQF09602.1\|798008_798641_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226884
LS483331.1\|SQF09599.1\|795286_796483_+\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309

Protein	Function_ID	Function_description	E-value
LS483331.1\|SQF09607.1\|801759_803199_+\|Collagen-like-surface-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.6226e-12
LS483331.1\|SQF09595.1\|792159_793116_+\|hypothetical-membrane-associated-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	1.65904e-113
LS483331.1\|SQF09622.1\|807906_809556_+\|two-component-sensor-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.69316e-77
LS483331.1\|SQF09616.1\|805629_806121_+\|PTS-system-mannose/fructose-family-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
LS483331.1\|SQF09591.1\|789861_791199_-\|UDP-N-acetylmuramoylalanyl-D-glutamate-2,-6-diaminopimelate-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.8359e-109
LS483331.1\|SQF09589.1\|789070_789862_-\|cobyric-acid-synthase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	6.74846e-142
LS483331.1\|SQF09606.1\|799670_801503_+\|GTP-binding-protein-LepA	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
LS483331.1\|SQF09600.1\|796492_797245_+\|oleoyl-[acyl-carrier-protein]-hydrolase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.74349e-109
LS483331.1\|SQF09603.1\|799139_799337_+\|nucleoside-diphosphate-kinase-protein-Ndk	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	2.09148e-09
LS483331.1\|SQF09620.1\|806943_807771_+\|phospotransferase-system-(PTS),-enzyme-II-component-D	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
LS483331.1\|SQF09618.1\|806137_806947_+\|PTS-system,-mannose-specific-IIC-component	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
LS483331.1\|SQF09596.1\|793169_794525_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
LS483331.1\|SQF09593.1\|791311_792163_+\|disA-bacterial-checkpoint-controller-nucleotide-binding-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.09715e-101
LS483331.1\|SQF09601.1\|797244_798009_+\|haloacid-dehalogenase-like-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.49715e-128
LS483331.1\|SQF09610.1\|803384_803822_+\|methionine-sulfoxide-reductase-B	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.35343e-84
LS483331.1\|SQF09614.1\|805177_805603_+\|PTS-system-mannose-specific-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.64459e-31
LS483331.1\|SQF09612.1\|803951_804971_+\|hypothetical-membrane-spanning-protein	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	6.6919e-100
LS483331.1\|SQF09602.1\|798008_798641_+\|membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	2.38885e-87
LS483331.1\|SQF09599.1\|795286_796483_+\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0

>LS483331.1|SQF09602.1|798008_798641_+|membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHKVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARRQRLNVE
>LS483331.1|SQF09601.1|797244_798009_+|haloacid-dehalogenase-like-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLAKQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>LS483331.1|SQF09600.1|796492_797245_+|oleoyl-[acyl-carrier-protein]-hydrolase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNILVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILSYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>LS483331.1|SQF09599.1|795286_796483_+|coproporphyrinogen-III-oxidase
MKNQGKWFIHKNILSPKWYNKTMSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFYSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>LS483331.1|SQF09598.1|794648_795290_+|acetyltransferase-GNAT-Family
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>LS483331.1|SQF09596.1|793169_794525_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>LS483331.1|SQF09595.1|792159_793116_+|hypothetical-membrane-associated-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVDKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>LS483331.1|SQF09593.1|791311_792163_+|disA-bacterial-checkpoint-controller-nucleotide-binding-family-protein
MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALTGTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEKFGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPLNADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAIGLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVTLPWYKKILGGKSK
>LS483331.1|SQF09591.1|789861_791199_-|UDP-N-acetylmuramoylalanyl-D-glutamate-2,-6-diaminopimelate-ligase
MKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDLSKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>LS483331.1|SQF09589.1|789070_789862_-|cobyric-acid-synthase
MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVAEKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLSSYDDILKQEITEEYADLKSKASFNKV
>LS483331.1|SQF09603.1|799139_799337_+|nucleoside-diphosphate-kinase-protein-Ndk
MEQTFFMIKPDGVKQGEVVGEVLRWIERLRFTFKRFELRQASSKYLAKHDEALVINLLILNLKLT
>LS483331.1|SQF09606.1|799670_801503_+|GTP-binding-protein-LepA
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDTSEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>LS483331.1|SQF09607.1|801759_803199_+|Collagen-like-surface-protein
MLTFGGASAVKANEQSNIGALQSQLQDLRENLPKVGDNIPDYNVLRKHEFYQHLQKFEDQLNLYLKVLDQNLSQLQGPRGDKGETGEQGPRGAQGPAGPQGPVGPAGKDGTQGPRGDKGETGEQGPRGAQGPAGPAGKDGTQGPRGDKGETGEQGPRGAQGPAGPQGPMGPAGERGEKGEPGTQGAKGDRGETGPAGPVGPRGDKGETGEQGPRGAQGPAGPQGPMGPAGERGEKGEPGTQGAKGDRGETGPAGPVGPRGDKGETGAKGEQGPAGKDGKAGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGKDGKDGQPGKPAPKTPEVPQKPGTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>LS483331.1|SQF09610.1|803384_803822_+|methionine-sulfoxide-reductase-B
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRIEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>LS483331.1|SQF09612.1|803951_804971_+|hypothetical-membrane-spanning-protein
MSTHLRKLPGLLLCLLLALSAWYLGRLFPIIGAPVFAILLGMLLALFYEHGDKTKEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGIGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLIGLSNEGFATFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYQAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>LS483331.1|SQF09614.1|805177_805603_+|PTS-system-mannose-specific-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>LS483331.1|SQF09616.1|805629_806121_+|PTS-system-mannose/fructose-family-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>LS483331.1|SQF09618.1|806137_806947_+|PTS-system,-mannose-specific-IIC-component
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>LS483331.1|SQF09620.1|806943_807771_+|phospotransferase-system-(PTS),-enzyme-II-component-D
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>LS483331.1|SQF09622.1|807906_809556_+|two-component-sensor-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE

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Crispr_ID: LS483331_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483331_2

1286382-1286475

Unclear

Consensus_repeat	Method
AATCCACTCACCCGTGAAGGGTGAGAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of LS483331_2

>merge|LS483331|2|1286382-1286475|CRISPRCasFinder
AATCCACTCACCCGTGAAGGGTGAGACCTAGTGGCTATGCGGAGTTACTTATCCAACTGATTATTTTAATCCACTCACCCGTGAAGGGTGAGAC

>LS483331|2|1|1286382-1286475|CRISPRCasFinder
AATCCACTCACCCGTGAAGGGTGAGAC	CTAGTGGCTATGCGGAGTTACTTATCCAACTGATTATTTT
AATCCACTCACCCGTGAAGGGTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
LS483331.1\|SQF10638.1\|1290876_1291440_-\|shikimate-kinase	unknown	unknown	gnl\|CDD\|379082
LS483331.1\|SQF10625.1\|1282700_1283324_-\|disulfide-interchange-protein	unknown	unknown	gnl\|CDD\|239264
LS483331.1\|SQF10629.1\|1284267_1285200_-\|magnesium-and-cobalt-transport-protein	unknown	unknown	gnl\|CDD\|213361
LS483331.1\|SQF10615.1\|1277723_1277828_-\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
LS483331.1\|SQF10617.1\|1277841_1278921_-\|cytoplasmic-protein	unknown	unknown	gnl\|CDD\|225197
LS483331.1\|SQF10619.1\|1278993_1280727_-\|two-component-sensor-kinase	unknown	unknown	gnl\|CDD\|225519
LS483331.1\|SQF10621.1\|1280723_1281464_-\|two-component-response-regulator	unknown	unknown	gnl\|CDD\|227095
LS483331.1\|SQF10632.1\|1285291_1286251_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|223745
LS483331.1\|SQF10642.1\|1292453_1292708_-\|Aldose-1-epimerase	unknown	unknown	gnl\|CDD\|286073
LS483331.1\|SQF10646.1\|1293992_1295066_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|273575
LS483331.1\|SQF10623.1\|1281551_1282658_-\|bifunctional-methionine-sulfoxide-reductase-A/B	unknown	unknown	gnl\|CDD\|184456
LS483331.1\|SQF10640.1\|1292040_1292436_-\|hypothetical-cytosolic-protein	unknown	unknown	gnl\|CDD\|181104
LS483331.1\|SQF10644.1\|1293184_1293937_+\|2-dehydro-3-deoxyphosphoheptonate-aldolase	unknown	unknown	gnl\|CDD\|172030
LS483331.1\|SQF10614.1\|1277111_1277645_-\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
LS483331.1\|SQF10650.1\|1295808_1296147_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
LS483331.1\|SQF10648.1\|1295501_1295807_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380388
LS483331.1\|SQF10634.1\|1286825_1288073_-\|ATP-dependent-RNA-helicase	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
LS483331.1\|SQF10627.1\|1283336_1284047_-\|cytochrome-c-type-biogenesis-protein	unknown	unknown	gnl\|CDD\|223856
LS483331.1\|SQF10636.1\|1288226_1290875_-\|valyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|235582
LS483331.1\|SQF10651.1\|1296199_1296955_-\|ubiE/COQ5-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|379312

Protein	Function_ID	Function_description	E-value
LS483331.1\|SQF10638.1\|1290876_1291440_-\|shikimate-kinase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.00452424
LS483331.1\|SQF10625.1\|1282700_1283324_-\|disulfide-interchange-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.7195e-35
LS483331.1\|SQF10629.1\|1284267_1285200_-\|magnesium-and-cobalt-transport-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.35313e-79
LS483331.1\|SQF10615.1\|1277723_1277828_-\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	2.84005e-07
LS483331.1\|SQF10617.1\|1277841_1278921_-\|cytoplasmic-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.00918e-35
LS483331.1\|SQF10619.1\|1278993_1280727_-\|two-component-sensor-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	2.08305e-64
LS483331.1\|SQF10621.1\|1280723_1281464_-\|two-component-response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.85886e-83
LS483331.1\|SQF10632.1\|1285291_1286251_-\|oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	4.87701e-56
LS483331.1\|SQF10642.1\|1292453_1292708_-\|Aldose-1-epimerase	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47
LS483331.1\|SQF10646.1\|1293992_1295066_+\|3-dehydroquinate-synthase	gnl\|CDD\|273575	TIGR01357, 3-dehydroquinate_synthase, 3-dehydroquinate synthase. This model represents 3-dehydroquinate synthase, the enzyme catalyzing the second of seven steps in the shikimate pathway of chorismate biosynthesis. Chorismate is the last common intermediate in the biosynthesis of all three aromatic amino acids. [Amino acid biosynthesis, Aromatic amino acid family].	9.25661e-164
LS483331.1\|SQF10623.1\|1281551_1282658_-\|bifunctional-methionine-sulfoxide-reductase-A/B	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	2.3863e-163
LS483331.1\|SQF10640.1\|1292040_1292436_-\|hypothetical-cytosolic-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000143012
LS483331.1\|SQF10644.1\|1293184_1293937_+\|2-dehydro-3-deoxyphosphoheptonate-aldolase	gnl\|CDD\|172030	PRK13397, PRK13397, 3-deoxy-7-phosphoheptulonate synthase; Provisional.	0
LS483331.1\|SQF10614.1\|1277111_1277645_-\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	1.40194e-80
LS483331.1\|SQF10650.1\|1295808_1296147_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.59437e-37
LS483331.1\|SQF10648.1\|1295501_1295807_-\|cupin-domain-containing-protein	gnl\|CDD\|380388	cd06983, cupin_dsy2733, Desulfitobacterium hafniense dsy2733 and related proteins, cupin domain. This family includes bacterial proteins homologous to dsy2733, a Desulfitobacterium hafniense protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.13368e-18
LS483331.1\|SQF10634.1\|1286825_1288073_-\|ATP-dependent-RNA-helicase	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.35517e-59
LS483331.1\|SQF10627.1\|1283336_1284047_-\|cytochrome-c-type-biogenesis-protein	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	6.4437e-43
LS483331.1\|SQF10636.1\|1288226_1290875_-\|valyl-tRNA-synthetase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
LS483331.1\|SQF10651.1\|1296199_1296955_-\|ubiE/COQ5-methyltransferase-family-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.89764e-26

>LS483331.1|SQF10632.1|1285291_1286251_-|oxidoreductase
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTQRLKGLIAAVELGDIVSVSSTTAYPNIDHVTWFRDLEKGGGTVHFMAPYALSYLPYLFDADIVSASGVAHFPKGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIYGTKGRLEIPHFWKNTHATLVRPDGSRSVIEAIMSSDFEAEAHHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK
>LS483331.1|SQF10629.1|1284267_1285200_-|magnesium-and-cobalt-transport-protein
MPTLPKASSAITLINLDQLTEHDQEALVSEGLIDAEVFDYAKDKNETSFMEENKEKLTIVFQILDRQEEAYHPNYIPRVIPITLFLNDQSLYILGHDHSLTLIEEVFPDLDESRSPRHLVFQLLTAFTKQYVPLMDEIAQQRDKLIEALRQKANKTNLESLANLQSGTVYILMGSKQNEQMLAELKDMPGQQDLEEDEAEQLRDAIIEARQLSNMCDLNTRVLKEISSSYNNVLSNNLNNNVTSLTIFSIGISIIAMVTSFYGMNVKLPFAKVDSVWFWIVLTTSLVALLIMVVMYWYVHKRNRNASKRI
>LS483331.1|SQF10627.1|1283336_1284047_-|cytochrome-c-type-biogenesis-protein
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFDKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>LS483331.1|SQF10625.1|1282700_1283324_-|disulfide-interchange-protein
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMTDKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>LS483331.1|SQF10623.1|1281551_1282658_-|bifunctional-methionine-sulfoxide-reductase-A/B
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>LS483331.1|SQF10621.1|1280723_1281464_-|two-component-response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>LS483331.1|SQF10619.1|1278993_1280727_-|two-component-sensor-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGKGIEDSSLTNSQSLLTRGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>LS483331.1|SQF10617.1|1277841_1278921_-|cytoplasmic-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYEDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>LS483331.1|SQF10615.1|1277723_1277828_-|B3/4-domain-containing-protein
MVEFVADQSFWELFPGAKLGVVLLKDVQNQAESP
>LS483331.1|SQF10614.1|1277111_1277645_-|B3/4-domain-containing-protein
MVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHAITSVHVLDKDNPHVPLFTEN
>LS483331.1|SQF10634.1|1286825_1288073_-|ATP-dependent-RNA-helicase
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEIVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQVNEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLIKVDKRLFEFFIVAFNC
>LS483331.1|SQF10636.1|1288226_1290875_-|valyl-tRNA-synthetase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>LS483331.1|SQF10638.1|1290876_1291440_-|shikimate-kinase
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>LS483331.1|SQF10640.1|1292040_1292436_-|hypothetical-cytosolic-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKDSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>LS483331.1|SQF10642.1|1292453_1292708_-|Aldose-1-epimerase
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY
>LS483331.1|SQF10644.1|1293184_1293937_+|2-dehydro-3-deoxyphosphoheptonate-aldolase
MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYNYFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVIQVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGVRGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMMEVHPDPDHALSDAAQQIDYKQLEQLGQELWQD
>LS483331.1|SQF10646.1|1293992_1295066_+|3-dehydroquinate-synthase
MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQTVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIGGGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPEAIIISTTFLETLPQREFSCGISEMLKIGFIHNRPLFQQLRDFQKETDKQGLERLIYQSISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAVSKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTETGFTTLAINKDDHQFVEKLDSLL
>LS483331.1|SQF10648.1|1295501_1295807_-|cupin-domain-containing-protein
MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD
>LS483331.1|SQF10650.1|1295808_1296147_-|cupin-domain-containing-protein
MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSLDKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQMLLVVVKPEA
>LS483331.1|SQF10651.1|1296199_1296955_-|ubiE/COQ5-methyltransferase-family-protein
MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLEVACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPFPDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDELRQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRRGLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483331_2	2.1\|1286409\|40\|LS483331\|CRISPRCasFinder	1286409-1286448	40	MK448679	Streptococcus phage Javan137, complete genome	35066-35105	8	0.8
LS483331_2	2.1\|1286409\|40\|LS483331\|CRISPRCasFinder	1286409-1286448	40	MK448950	Streptococcus phage Javan464, complete genome	37224-37263	9	0.775

1. spacer 2.1|1286409|40|LS483331|CRISPRCasFinder matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 8, identity: 0.8

ctagtggctatgcggagttacttatccaactgattatttt	CRISPR spacer
ctagtggctatgcggagttacttatccaaattatcgagga	Protospacer
***************************** * **..

2. spacer 2.1|1286409|40|LS483331|CRISPRCasFinder matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 9, identity: 0.775

ctagtggctatgcggagttacttatccaactgattatttt	CRISPR spacer
cgagtggctatgcggagttgcttatccaactaatcgagga	Protospacer
* *****************.***********.**..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36590 : 48950

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF08238.1\|36590_40364_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.1e-40	26.8
SQF08242.1\|40524_41979_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	33.3
SQF08244.1\|42006_43029_+	phosphoribosylaminoimidazole synthetase	R9TMC7	Synechococcus_phage	4.0e-63	41.5
SQF08246.1\|43196_43751_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
SQF08248.1\|43934_45482_+	IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
SQF08250.1\|45538_46663_-	bacterial SH3 domain protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
SQF08252.1\|46825_48181_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
SQF08254.1\|48338_48950_+	phosphoribosyl carboxyaminoimidazole mutase	A0A2P0VNU7	Tetraselmis_virus	3.6e-19	43.1

DBSCAN-SWA_2

183990 : 205120

Shigella_phage(33.33%)

transposase,bacteriocin,integrase,tRNA

attL 177440:177453|attR 186851:186864

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
177440:177453	attL	NA	NA	NA	NA
SQF08530.1\|183990_184212_-\|transposase	transposase	U5P429	Shigella_phage	1.9e-10	44.3
SQF08531.1\|184251_184422_-\|integrase	integrase	U5P429	Shigella_phage	5.7e-07	44.4
SQF08532.1\|184853_185147_-\|transposase	transposase	NA	NA	NA	NA
SQF08534.1\|185224_186535_-	membrane protein	NA	NA	NA	NA
SQF08535.1\|186758_187631_+	nicotinate-nucleotide pyrophosphorylase	NA	NA	NA	NA
186851:186864	attR	NA	NA	NA	NA
SQF08536.1\|187930_188737_-\|transposase	transposase, IS861	A0A1B1P773	Bacillus_phage	4.1e-63	49.6
SQF08537.1\|188757_189273_-\|transposase	transposase	NA	NA	NA	NA
SQF08538.1\|189358_190222_-	membrane protein	NA	NA	NA	NA
SQF08539.1\|190440_191583_+\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.8e-86	43.9
SQF08540.1\|191799_192111_+	helper of Tim protein 13	NA	NA	NA	NA
SQF08541.1\|192114_192654_+	biotin transporter	NA	NA	NA	NA
SQF08542.1\|192793_193573_+	metal-dependent hydrolase	NA	NA	NA	NA
SQF08543.1\|193572_194088_+\|tRNA	tRNA-specific adenosine deaminase	NA	NA	NA	NA
SQF08544.1\|194701_195922_-	S-layer protein	NA	NA	NA	NA
SQF08545.1\|196408_196786_-	Uncharacterised protein	NA	NA	NA	NA
SQF08547.1\|196978_197311_+	regulatory protein	NA	NA	NA	NA
SQF08548.1\|197319_198057_+	RevS	A0A2H4J4Z6	uncultured_Caudovirales_phage	1.0e-12	24.2
SQF08549.1\|198056_199400_+	putative sensor histidine kinase BlpH	NA	NA	NA	NA
SQF08550.1\|199470_199614_-	Uncharacterised protein	NA	NA	NA	NA
SQF08551.1\|200013_200127_+	Uncharacterised protein	NA	NA	NA	NA
SQF08552.1\|201098_203249_+	ABC transporter CbaT	W8CYL7	Bacillus_phage	4.2e-46	29.8
SQF08553.1\|203257_204619_+	transport protein ComB	NA	NA	NA	NA
SQF08554.1\|204760_204934_+	Uncharacterised protein	NA	NA	NA	NA
SQF08555.1\|204952_205120_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA

DBSCAN-SWA_3

344865 : 405186

Streptococcus_phage(35.0%)

transposase,bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF08802.1\|344865_345456_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
SQF08803.1\|345947_346223_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQF08804.1\|346471_347107_+	thymidylate kinase	M1PSC7	Streptococcus_phage	2.7e-65	63.4
SQF08805.1\|347124_348000_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
SQF08806.1\|348662_348986_+	DNA replication initiation control protein	M1PFV3	Streptococcus_phage	1.3e-28	59.4
SQF08807.1\|348990_349854_+	corrin/porphyrin methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	74.7
SQF08808.1\|349880_350273_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF08809.1\|350319_350949_-	copper homeostasis protein	NA	NA	NA	NA
SQF08810.1\|351248_351605_+	arsenate reductase	M1PLC0	Streptococcus_phage	6.3e-40	65.8
SQF08812.1\|351678_352506_-	3'-exo-deoxyribonuclease	M1PSC0	Streptococcus_phage	3.8e-128	79.5
SQF08815.1\|352739_353921_+	L-lactate oxidase	NA	NA	NA	NA
SQF08817.1\|354186_359124_+	LPXTG-motif cell wall anchor domain protein	NA	NA	NA	NA
SQF08820.1\|359896_360604_+	permease	NA	NA	NA	NA
SQF08822.1\|360846_362844_+\|tRNA	methionyl-tRNA synthetase	A0A1V0SHR2	Klosneuvirus	3.0e-86	35.0
SQF08824.1\|363338_364352_+	ribonucleotide-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	5.5e-97	53.4
SQF08826.1\|364355_364844_+	nrdI protein	R4JF54	Bacillus_phage	1.3e-11	37.5
SQF08828.1\|364810_366991_+	ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.5e-171	43.3
SQF08830.1\|367195_367948_-	ADP-ribosyltransferase	NA	NA	NA	NA
SQF08833.1\|368406_368880_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF08834.1\|369326_369731_+	Uncharacterised protein	NA	NA	NA	NA
SQF08835.1\|370459_371374_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	4.8e-76	50.3
SQF08836.1\|371865_372321_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF08837.1\|372564_372816_+	hypothetical membrane spanning protein	NA	NA	NA	NA
SQF08839.1\|372910_373576_-	phage protein	NA	NA	NA	NA
SQF08841.1\|374267_375236_-	Protein of uncharacterised function (DUF3644)	A0A0N9RUA4	Staphylococcus_phage	5.8e-88	52.0
SQF08843.1\|375959_376196_+	Protein of uncharacterised function (DUF2829)	NA	NA	NA	NA
SQF08845.1\|376188_376887_+	3-ketoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	6.0e-10	24.8
SQF08846.1\|376962_377922_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
SQF08848.1\|378254_379592_+	phosphoglycerate transporter protein	NA	NA	NA	NA
SQF08850.1\|379764_381147_+	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L4K9	Tupanvirus	8.5e-32	36.0
SQF08852.1\|381177_381732_+	ADP-ribose pyrophosphatase	NA	NA	NA	NA
SQF08854.1\|381731_381983_+	membrane protein	NA	NA	NA	NA
SQF08855.1\|382002_382698_+	MTA/SAH nucleosidase	NA	NA	NA	NA
SQF08858.1\|382848_383190_+	Uncharacterised protein	NA	NA	NA	NA
SQF08860.1\|383288_383936_-	metalloregulator ScaR	NA	NA	NA	NA
SQF08862.1\|384081_385014_+	manganese-binding protein	NA	NA	NA	NA
SQF08864.1\|385077_385803_+	manganese transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.1e-17	32.6
SQF08866.1\|385803_386658_+	ABC 3 transport family protein	NA	NA	NA	NA
SQF08868.1\|386805_387612_-	cyclophilin type peptidyl-prolyl cis-trans isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
SQF08869.1\|387828_390234_+	cell division protein FtsK	S5VNE3	Mycobacterium_phage	2.9e-88	51.7
SQF08871.1\|390303_390657_-	integral membrane protein	NA	NA	NA	NA
SQF08873.1\|390900_391326_+	50S ribosomal protein L11	NA	NA	NA	NA
SQF08875.1\|391431_392121_+	50S ribosomal protein L1	NA	NA	NA	NA
SQF08878.1\|392442_393171_+	uridylate kinase	NA	NA	NA	NA
SQF08879.1\|393199_393757_+	ribosome recycling factor	NA	NA	NA	NA
SQF08880.1\|393865_394723_+	s1 RNA binding domain	NA	NA	NA	NA
SQF08881.1\|394795_395305_+	methionine sulfoxide reductase A	NA	NA	NA	NA
SQF08884.1\|395301_395517_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQF08886.1\|395672_396848_+	lysM domain protein	A0A0E3XB61	Gordonia_phage	5.5e-16	40.5
SQF08888.1\|397161_398934_+	myosin-cross-reactive antigen	NA	NA	NA	NA
SQF08890.1\|399092_400145_+	phosphate starvation-induced protein	W8D063	Erwinia_phage	6.0e-46	49.5
SQF08893.1\|400190_400766_+	uracil DNA glycosylase superfamily protein	NA	NA	NA	NA
SQF08895.1\|400924_401422_+\|protease	metalloprotease	NA	NA	NA	NA
SQF08897.1\|401402_401810_+	diacylglycerol kinase	NA	NA	NA	NA
SQF08898.1\|401929_402826_+	GTP-binding protein Era	NA	NA	NA	NA
SQF08901.1\|402846_403323_+	phosphohydrolase	NA	NA	NA	NA
SQF08902.1\|403629_403884_-	Uncharacterised protein	NA	NA	NA	NA
SQF08904.1\|404281_404416_+\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQF08906.1\|404516_404699_+\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQF08909.1\|405036_405186_-\|transposase	IS1191 transposase	NA	NA	NA	NA

DBSCAN-SWA_4

457790 : 464441

Streptococcus_phage(66.67%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF09003.1\|457790_458000_-	vanUG2	A0A2K5B263	Erysipelothrix_phage	1.3e-16	61.5
SQF09005.1\|457989_458280_-	Chromosome segregation ATPase	NA	NA	NA	NA
SQF09006.1\|458276_459647_-	ATPase	NA	NA	NA	NA
SQF09009.1\|459637_459868_-	Uncharacterised protein	NA	NA	NA	NA
SQF09011.1\|459867_460425_-	Uncharacterised protein	NA	NA	NA	NA
SQF09013.1\|460795_460954_+	prophage LambdaSa04	A0A1B0RXD3	Streptococcus_phage	3.0e-18	84.6
SQF09014.1\|461008_461311_+	Plasmid stabilization system antitoxin protein	NA	NA	NA	NA
SQF09016.1\|461310_461616_+	prophage LambdaSa04, RelE/ParE family protein	NA	NA	NA	NA
SQF09018.1\|461634_461907_+	cytoplasmic protein	E4ZFM1	Streptococcus_phage	4.1e-07	50.7
SQF09020.1\|462011_462464_+\|portal	portal protein	E4ZFM3	Streptococcus_phage	1.3e-61	85.6
SQF09022.1\|462529_462838_+	prophage minor structural protein	Q6DMT0	Streptococcus_phage	2.8e-20	63.5
SQF09024.1\|463254_463593_+	huntington interacting protein HYPE	NA	NA	NA	NA
SQF09026.1\|463616_464441_+	asparagine ligase A	M1PB22	Moumouvirus	3.6e-22	33.5

DBSCAN-SWA_5

647559 : 658163

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF09346.1\|647559_649770_-	phosphoglycerol transferase	W6LM83	Streptococcus_phage	6.5e-268	68.9
SQF09349.1\|649877_651041_+	SAM-dependent methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
SQF09352.1\|651037_651724_+	3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
SQF09354.1\|651817_652984_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
SQF09356.1\|653044_653386_+	hypothetical cytosolic protein	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
SQF09358.1\|653607_654960_+	glutathione reductase	A0A2K5B2C5	Erysipelothrix_phage	5.9e-30	24.7
SQF09360.1\|655047_656316_-	folylpolyglutamate synthase	NA	NA	NA	NA
SQF09363.1\|656345_656786_-	membrane protein	NA	NA	NA	NA
SQF09365.1\|657020_658163_+	aminotransferase class-V family protein	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3

DBSCAN-SWA_6

685109 : 722772

Bacillus_phage(23.08%)

transposase,head,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF09418.1\|685109_685841_+\|tRNA	tRNA (guanine-N(1)-)-methyltransferase	NA	NA	NA	NA
SQF09419.1\|685840_686833_+	thioredoxin reductase	Q9JRK7	Streptococcus_phage	8.2e-29	54.9
SQF09420.1\|687010_688069_+	regulatory protein	NA	NA	NA	NA
SQF09421.1\|688081_689005_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
SQF09422.1\|689260_689974_+	deoR-like helix-turn-helix domain-containing protein	A0A077SK06	Escherichia_phage	3.2e-19	32.1
SQF09423.1\|689970_690882_+	1-phosphofructokinase	NA	NA	NA	NA
SQF09425.1\|690878_692825_+	PTS system fructose-specific transporter subunit IIABC	NA	NA	NA	NA
SQF09427.1\|692923_693517_+	N-acetylmuramidase	A0A249Y0X5	Enterococcus_phage	3.5e-11	33.8
SQF09429.1\|693668_694376_+	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q332B8	Clostridium_botulinum_C_phage	6.5e-12	36.4
SQF09432.1\|694531_694651_-\|transposase	degenerate transposase	NA	NA	NA	NA
SQF09434.1\|694947_695622_-	exotoxin J	NA	NA	NA	NA
SQF09436.1\|695786_696533_-	Exotoxin type C precursor	Q938J1	Temperate_phage	4.0e-113	82.4
SQF09439.1\|696652_697672_-\|protease	igG-degrading protease	NA	NA	NA	NA
SQF09441.1\|698174_698351_+	nucleoside diphosphate kinase	NA	NA	NA	NA
SQF09443.1\|698578_698959_+\|transposase	transposase	NA	NA	NA	NA
SQF09444.1\|698958_699807_+	degV family protein	NA	NA	NA	NA
SQF09445.1\|699931_701140_+\|head	poly A polymerase head domain-containing protein	H7BUW3	unidentified_phage	5.3e-38	45.0
SQF09448.1\|701136_703014_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.5e-63	31.5
SQF09451.1\|703905_704316_+	polypeptide deformylase family protein	E3SLL2	Synechococcus_phage	6.9e-06	30.6
SQF09453.1\|704396_706409_-	5'-nucleotidase	NA	NA	NA	NA
SQF09455.1\|706628_707279_+	GTP pyrophosphokinase	NA	NA	NA	NA
SQF09457.1\|707281_707950_+	two-component response regulator	W8CYM9	Bacillus_phage	2.3e-19	28.8
SQF09459.1\|707958_709191_+	two component system histidine kinase	NA	NA	NA	NA
SQF09462.1\|709484_710363_+	mevalonate kinase	NA	NA	NA	NA
SQF09464.1\|710344_711289_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
SQF09466.1\|711281_712295_+	phosphomevalonate kinase	NA	NA	NA	NA
SQF09468.1\|712281_713271_+	isopentenyl pyrophosphate isomerase	NA	NA	NA	NA
SQF09470.1\|713500_714778_-	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
SQF09472.1\|714764_715940_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
SQF09474.1\|716124_716988_+	thymidylate synthase	U5J9N5	Bacillus_phage	1.7e-83	53.2
SQF09475.1\|717067_717565_+	dihydrofolate reductase	W5QU76	Bacillus_phage	1.1e-10	34.4
SQF09478.1\|717584_717755_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF09480.1\|717884_719114_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	7.8e-138	60.5
SQF09482.1\|719123_719723_+	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
SQF09484.1\|719870_720620_+	virulence factor relevant regulator	NA	NA	NA	NA
SQF09485.1\|720672_722772_-\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	3.0e-121	39.2

DBSCAN-SWA_7

958078 : 1032795

100

Streptococcus_phage(54.41%)

portal,integrase,tRNA,tail,terminase,protease

attL 991431:991490|attR 1032838:1032933

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF09932.1\|958078_958963_-\|tRNA	tRNA pseudouridine synthase B	NA	NA	NA	NA
SQF09933.1\|959078_960419_-	Serine/threonine-protein kinase MRCK beta	NA	NA	NA	NA
SQF09934.1\|960515_961472_-	membrane protein	NA	NA	NA	NA
SQF09935.1\|961482_962079_-	type I restriction-modification system specificty subunit	NA	NA	NA	NA
SQF09936.1\|962170_964807_-	permease family protein	NA	NA	NA	NA
SQF09937.1\|964821_965523_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	37.0
SQF09938.1\|965640_966183_+	bacterial regulatory s, tetR family protein	NA	NA	NA	NA
SQF09939.1\|966325_966967_-	bacterial regulatory s, gntR family protein	NA	NA	NA	NA
SQF09940.1\|967129_967618_-	general stress protein, Gls24 family	NA	NA	NA	NA
SQF09942.1\|967628_967829_-	csbD-like family protein	J7KJ36	Streptococcus_phage	1.8e-07	51.5
SQF09944.1\|967869_968409_-	response regulator	NA	NA	NA	NA
SQF09947.1\|968421_968610_-	membrane protein	NA	NA	NA	NA
SQF09949.1\|968620_969208_-	membrane protein	NA	NA	NA	NA
SQF09951.1\|969268_969517_-	transglycosylase associated family protein	NA	NA	NA	NA
SQF09954.1\|969879_972198_-	DNA helicase II / ATP-dependent DNA helicase PcrA	A7KV33	Bacillus_phage	2.3e-130	40.9
SQF09955.1\|972726_974049_+	amino acid symporter	NA	NA	NA	NA
SQF09958.1\|974168_975404_+	cation diffusion facilitator transporter family protein	NA	NA	NA	NA
SQF09960.1\|975773_976547_-	protein B	NA	NA	NA	NA
SQF09962.1\|976916_977753_-	polar amino acid ABC uptake transporter substrate binding protein	NA	NA	NA	NA
SQF09965.1\|977768_978398_-	histidine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-27	35.5
SQF09967.1\|978407_979049_-	histidine transporter permease	NA	NA	NA	NA
SQF09969.1\|979155_979491_-	phosphonoacetate hydrolase	NA	NA	NA	NA
SQF09971.1\|979686_981501_-	glucosamine-fructose-6-phosphate aminotransferase	A7IW18	Paramecium_bursaria_Chlorella_virus	6.8e-98	38.6
SQF09973.1\|981676_982234_-	signal peptidase I	NA	NA	NA	NA
SQF09975.1\|982451_983954_-	pyruvate kinase	NA	NA	NA	NA
SQF09977.1\|984016_985030_-	6-phosphofructokinase	NA	NA	NA	NA
SQF09979.1\|985109_988220_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	8.3e-120	29.9
SQF09982.1\|988404_988776_+	GntR family transcriptional regulator	NA	NA	NA	NA
SQF09984.1\|988775_989474_+	ABC transporter family protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
SQF09986.1\|989483_990269_+	ABC transporter permease protein	NA	NA	NA	NA
SQF09988.1\|990395_991010_-	membrane protein	M1Q152	Streptococcus_phage	4.0e-50	51.8
991431:991490	attL	NA	NA	NA	NA
SQF09990.1\|991600_991789_-	paratox	A3F673	Streptococcus_phage	6.5e-20	81.4
SQF09992.1\|992028_992787_+	DNA/RNA non-specific endonuclease family protein	NA	NA	NA	NA
SQF09993.1\|992897_993605_+	exotoxin type C	A0A097PAT7	Streptococcus_pyogenes_phage	5.1e-09	26.7
SQF09994.1\|993673_994426_-	phage-associated cell wall hydrolase	A3F665	Streptococcus_phage	2.1e-141	97.2
SQF09995.1\|994427_994760_-	N-acetylmuramoyl-L-alanine amidase	A3F664	Streptococcus_phage	2.8e-50	98.2
SQF09996.1\|994772_995093_-	Uncharacterised protein	A3F663	Streptococcus_phage	1.2e-50	99.1
SQF09997.1\|995103_995715_-	phage protein	Q938J7	Temperate_phage	1.1e-84	93.6
SQF09998.1\|995717_996149_-	phage protein	Q938J8	Temperate_phage	1.1e-73	100.0
SQF09999.1\|996160_998044_-	phage protein	Q938J9	Temperate_phage	8.0e-251	96.5
SQF10000.1\|998058_999072_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	9.5e-182	98.5
SQF10002.1\|999068_1001213_-	Phage endopeptidase	Q938K1	Temperate_phage	0.0e+00	98.2
SQF10003.1\|1001209_1001917_-	phage protein	Q938K2	Temperate_phage	1.7e-92	70.6
SQF10004.1\|1001916_1005840_-\|tail	phage tail protein	J7KDT4	Streptococcus_phage	2.6e-243	49.1
SQF10005.1\|1006049_1006376_-	phage protein	J7KK85	Streptococcus_phage	6.4e-39	75.0
SQF10006.1\|1006428_1007040_-\|tail	major tail protein	J7KKC8	Streptococcus_phage	1.8e-74	73.0
SQF10007.1\|1007056_1007482_-	phage protein	J7KBZ9	Streptococcus_phage	2.9e-68	85.8
SQF10008.1\|1007478_1007856_-	phage protein	J7KDM3	Streptococcus_phage	1.8e-45	73.6
SQF10009.1\|1007852_1008200_-	phage protein	J7KJ42	Streptococcus_phage	2.1e-48	84.5
SQF10010.1\|1008196_1008499_-	phage protein	J7KC36	Streptococcus_phage	2.6e-42	87.8
SQF10011.1\|1008643_1009828_-	phage protein	J7KJ82	Streptococcus_phage	1.2e-162	76.1
SQF10013.1\|1009851_1010517_-\|protease	phage ClpP protease	M1Q115	Streptococcus_phage	5.4e-93	78.6
SQF10014.1\|1010494_1011715_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	3.4e-186	81.7
SQF10015.1\|1011748_1011973_-	phage protein	Q938K9	Temperate_phage	3.6e-17	61.4
SQF10016.1\|1011965_1012136_-	phage protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
SQF10017.1\|1012132_1013887_-\|terminase	phage terminase, large subunit	J7KKD1	Streptococcus_phage	0.0e+00	96.2
SQF10018.1\|1013901_1014369_-\|terminase	phage terminase, small subunit	J7KC46	Streptococcus_phage	3.9e-82	98.7
SQF10019.1\|1014536_1014878_-	Phage endonuclease	J7KH36	Streptococcus_phage	2.5e-54	90.7
SQF10020.1\|1015475_1015910_-	autolysin regulatory protein	J7KDQ1	Streptococcus_phage	2.2e-71	94.4
SQF10021.1\|1016192_1016363_-	phage protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
SQF10022.1\|1016359_1016863_-	phage protein	A0A097PAV5	Streptococcus_pyogenes_phage	1.5e-92	99.4
SQF10023.1\|1016859_1017153_-	phage protein	A0A097PAR1	Streptococcus_pyogenes_phage	4.2e-50	100.0
SQF10024.1\|1017149_1017335_-	phage protein	A0A097PBF0	Streptococcus_pyogenes_phage	7.0e-27	100.0
SQF10026.1\|1017359_1017548_-	DNA N-4 cytosine methyltransferase M.NgoMXV	A0A097PAU8	Streptococcus_pyogenes_phage	1.2e-13	97.1
SQF10027.1\|1017550_1017886_-	Uncharacterised protein	A0A097PAS4	Streptococcus_pyogenes_phage	4.7e-45	100.0
SQF10028.1\|1017888_1018173_-	phage membrane protein	A0A097PAV1	Streptococcus_pyogenes_phage	5.0e-40	91.5
SQF10030.1\|1018169_1018340_-	phage protein	Q938M0	Temperate_phage	8.5e-11	100.0
SQF10033.1\|1018336_1018750_-	phage protein	Q938M1	Temperate_phage	1.2e-34	63.1
SQF10035.1\|1018746_1019031_-	phage protein	A0A1P8VVP5	Streptococcus_phage	1.3e-48	96.8
SQF10037.1\|1019024_1019276_-	phage protein	A0A1P8VVV4	Streptococcus_phage	8.9e-41	94.0
SQF10039.1\|1019272_1019629_-	phage protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
SQF10042.1\|1019625_1020066_-	phage protein	A0A097PAS0	Streptococcus_pyogenes_phage	1.6e-80	98.6
SQF10044.1\|1020274_1020766_-	single strand binding protein	A0A286QNX2	Streptococcus_phage	7.6e-60	74.2
SQF10046.1\|1020758_1021433_-	Single-stranded DNA-binding protein	Q938M8	Temperate_phage	2.0e-103	96.9
SQF10048.1\|1021433_1021916_-	phage protein	Q938M9	Temperate_phage	1.6e-49	98.8
SQF10049.1\|1021937_1022192_-	phage protein	Q938N0	Temperate_phage	6.3e-42	97.6
SQF10052.1\|1022172_1022529_-	phage protein	A0A097PAU3	Streptococcus_pyogenes_phage	3.0e-50	99.2
SQF10054.1\|1022539_1022677_-	phage protein	J7KBQ4	Streptococcus_phage	2.7e-07	78.4
SQF10056.1\|1022667_1023450_-	DNA replication protein DnaC	A0A097PAQ0	Streptococcus_pyogenes_phage	2.7e-144	98.1
SQF10058.1\|1023436_1024240_-	DNA replication protein DnaC	A0A2P0VI76	Streptococcus_phage	2.4e-63	53.8
SQF10061.1\|1024355_1024799_-	Uncharacterised protein	NA	NA	NA	NA
SQF10063.1\|1024854_1025235_+	Uncharacterised protein	NA	NA	NA	NA
SQF10065.1\|1025224_1025497_-	Uncharacterised protein	NA	NA	NA	NA
SQF10067.1\|1025669_1025849_-	Uncharacterised protein	A0A1X9I5M8	Streptococcus_phage	1.2e-12	65.5
SQF10069.1\|1025979_1026114_-	phage protein	A0A1P8VVR9	Streptococcus_phage	3.3e-18	97.7
SQF10071.1\|1026110_1026407_-	phage protein	A0A097PAT8	Streptococcus_pyogenes_phage	1.2e-47	96.9
SQF10074.1\|1026542_1026686_+	Uncharacterised protein	M1PFC9	Streptococcus_phage	2.4e-11	72.3
SQF10076.1\|1026658_1026835_-	Uncharacterised protein	NA	NA	NA	NA
SQF10077.1\|1026848_1027088_-	Cro/CI family phage transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	9.1e-35	96.2
SQF10078.1\|1027181_1027853_+	phage protein	A0A1S5S8U0	Streptococcus_phage	7.0e-40	39.9
SQF10079.1\|1027809_1027935_-	Uncharacterised protein	X2KTZ3	Streptococcus_phage	4.8e-11	85.4
SQF10080.1\|1027969_1028128_-	phage membrane protein	J7KH24	Streptococcus_phage	1.3e-21	90.4
SQF10081.1\|1028186_1028402_+	Uncharacterised protein	J7KBX0	Streptococcus_phage	8.8e-29	97.1
SQF10083.1\|1028387_1028537_-	Uncharacterised protein	J7KH12	Streptococcus_phage	9.7e-19	89.8
SQF10085.1\|1028631_1028733_-	Uncharacterised protein	NA	NA	NA	NA
SQF10086.1\|1028907_1029696_+	Phage transcriptional repressor	A0A1S5SD15	Streptococcus_phage	1.4e-87	63.8
SQF10087.1\|1029774_1030671_+	ATP-binding region, ATPase family protein	NA	NA	NA	NA
SQF10088.1\|1030685_1031045_+	Uncharacterised protein	NA	NA	NA	NA
SQF10089.1\|1031041_1031587_+	Predicted nucleic acid-binding protein, contains PIN domain	NA	NA	NA	NA
SQF10091.1\|1031706_1032795_+\|integrase	integrase	Q38159	Streptococcus_phage	7.2e-204	99.7
1032838:1032933	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LS483331

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection