CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483351	Streptococcus pyogenes strain NCTC8195 genome assembly, chromosome: 1	1 crisprs	DinG,csm6,cas3,DEDDh,csa3	0	0	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483351_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483351_1

1050449-1050550

Orphan

Consensus_repeat	Method
AATAATTGGTATAGTCTAATTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483351_1

>merge|LS483351|1|1050449-1050550|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATACCGATAAAAACATTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACATAAAATTGGTATAGTCTAATTATA

>LS483351|1|1|1050449-1050550|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATA	CCGATAAAAACATTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACA
TAAAATTGGTATAGTCTAATTATA

Protein	Signature genes	Signature genes Name	Protein_function
LS483351.1\|SQF45605.1\|1041624_1042947_+\|amino-acid-symporter	unknown	unknown	gnl\|CDD\|224040
LS483351.1\|SQF45637.1\|1060501_1060690_-\|paratox	unknown	unknown	unknown
LS483351.1\|SQF45629.1\|1057301_1057673_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
LS483351.1\|SQF45615.1\|1047304_1047946_-\|histidine-transporter-permease	unknown	unknown	gnl\|CDD\|223836
LS483351.1\|SQF45613.1\|1046665_1047295_-\|histidine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
LS483351.1\|SQF45623.1\|1051348_1052851_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
LS483351.1\|SQF45603.1\|1038777_1041096_-\|DNA-helicase-II-/-ATP-dependent-DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
LS483351.1\|SQF45631.1\|1057672_1058371_+\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|224054
LS483351.1\|SQF45639.1\|1060927_1061728_+\|streptodornase	unknown	unknown	gnl\|CDD\|372824
LS483351.1\|SQF45601.1\|1038167_1038416_-\|transglycosylase-associated-family-protein	unknown	unknown	gnl\|CDD\|225170
LS483351.1\|SQF45619.1\|1048583_1050398_-\|glucosamine-fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
LS483351.1\|SQF45621.1\|1050573_1051131_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
LS483351.1\|SQF45611.1\|1045813_1046650_-\|polar-amino-acid-ABC-uptake-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
LS483351.1\|SQF45617.1\|1048052_1048388_-\|phosphonoacetate-hydrolase	unknown	unknown	gnl\|CDD\|225380
LS483351.1\|SQF45609.1\|1044671_1045445_-\|protein-B	unknown	unknown	gnl\|CDD\|369335
LS483351.1\|SQF45633.1\|1058380_1059166_+\|ABC-transporter-permease-protein	unknown	unknown	unknown
LS483351.1\|SQF45627.1\|1054006_1057117_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
LS483351.1\|SQF45635.1\|1059296_1059911_-\|membrane-protein	unknown	unknown	gnl\|CDD\|223475
LS483351.1\|SQF45625.1\|1052913_1053927_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
LS483351.1\|SQF45607.1\|1043066_1044302_+\|cation-diffusion-facilitator-transporter-family-protein	unknown	unknown	gnl\|CDD\|223131

Protein	Function_ID	Function_description	E-value
LS483351.1\|SQF45605.1\|1041624_1042947_+\|amino-acid-symporter	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
LS483351.1\|SQF45629.1\|1057301_1057673_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	1.32055e-48
LS483351.1\|SQF45615.1\|1047304_1047946_-\|histidine-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.36474e-71
LS483351.1\|SQF45613.1\|1046665_1047295_-\|histidine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.89978e-111
LS483351.1\|SQF45623.1\|1051348_1052851_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
LS483351.1\|SQF45603.1\|1038777_1041096_-\|DNA-helicase-II-/-ATP-dependent-DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
LS483351.1\|SQF45631.1\|1057672_1058371_+\|ABC-transporter-family-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.28377e-64
LS483351.1\|SQF45639.1\|1060927_1061728_+\|streptodornase	gnl\|CDD\|372824	pfam13930, Endonuclea_NS_2, DNA/RNA non-specific endonuclease.	7.11109e-26
LS483351.1\|SQF45601.1\|1038167_1038416_-\|transglycosylase-associated-family-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
LS483351.1\|SQF45619.1\|1048583_1050398_-\|glucosamine-fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
LS483351.1\|SQF45621.1\|1050573_1051131_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
LS483351.1\|SQF45611.1\|1045813_1046650_-\|polar-amino-acid-ABC-uptake-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.79673e-109
LS483351.1\|SQF45617.1\|1048052_1048388_-\|phosphonoacetate-hydrolase	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	1.37463e-64
LS483351.1\|SQF45609.1\|1044671_1045445_-\|protein-B	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	3.19117e-97
LS483351.1\|SQF45627.1\|1054006_1057117_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
LS483351.1\|SQF45635.1\|1059296_1059911_-\|membrane-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
LS483351.1\|SQF45625.1\|1052913_1053927_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
LS483351.1\|SQF45607.1\|1043066_1044302_+\|cation-diffusion-facilitator-transporter-family-protein	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	9.55614e-95

>LS483351.1|SQF45619.1|1048583_1050398_-|glucosamine-fructose-6-phosphate-aminotransferase
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>LS483351.1|SQF45617.1|1048052_1048388_-|phosphonoacetate-hydrolase
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVFDSNGVRLSDGDTITVIKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>LS483351.1|SQF45615.1|1047304_1047946_-|histidine-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKVPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>LS483351.1|SQF45613.1|1046665_1047295_-|histidine-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>LS483351.1|SQF45611.1|1045813_1046650_-|polar-amino-acid-ABC-uptake-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKERQNKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>LS483351.1|SQF45609.1|1044671_1045445_-|protein-B
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKSFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>LS483351.1|SQF45607.1|1043066_1044302_+|cation-diffusion-facilitator-transporter-family-protein
MTQDPIANLKLARKGPIVSIIVYLLLSAAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKAEQLLSDQFSIYDIDIHVEPAMILEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLVDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQITPIAKRQLHHTHYRIVKM
>LS483351.1|SQF45605.1|1041624_1042947_+|amino-acid-symporter
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNESVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>LS483351.1|SQF45603.1|1038777_1041096_-|DNA-helicase-II-/-ATP-dependent-DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALSLNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANSLGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>LS483351.1|SQF45601.1|1038167_1038416_-|transglycosylase-associated-family-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN
>LS483351.1|SQF45621.1|1050573_1051131_-|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>LS483351.1|SQF45623.1|1051348_1052851_-|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>LS483351.1|SQF45625.1|1052913_1053927_-|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>LS483351.1|SQF45627.1|1054006_1057117_-|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDAKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>LS483351.1|SQF45629.1|1057301_1057673_+|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQYVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>LS483351.1|SQF45631.1|1057672_1058371_+|ABC-transporter-family-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>LS483351.1|SQF45633.1|1058380_1059166_+|ABC-transporter-permease-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>LS483351.1|SQF45635.1|1059296_1059911_-|membrane-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>LS483351.1|SQF45637.1|1060501_1060690_-|paratox
MLTYDEFKQAIDRGYITGDTVMIVRKNGQIFDYVLPHEKVKNGEVVTEEIVEEVMVELDYIK
>LS483351.1|SQF45639.1|1060927_1061728_+|streptodornase
MSKSNRRTWQGLVVILIAILTTFTTSTVTAARKIRNFPDTTEILLGTKATETPGILPFTGSYQLVLGDLDNLQRPTFAHIQLKDQDEPNIKRKGLKFNPPGWHNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYYENRLDSWLALHPNFWLDYKVTPVYHKNELVPRQVVLQYVGIDENGDLLQIKLGSEKESVDNFGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNLETEEFEEAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36589 : 48952

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF43542.1\|36589_40363_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.6e-40	27.0
SQF43545.1\|40523_41978_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	33.3
SQF43547.1\|42005_43028_+	phosphoribosylaminoimidazole synthetase	A0A0E3FGG1	Synechococcus_phage	6.9e-63	41.4
SQF43549.1\|43195_43750_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
SQF43551.1\|43933_45481_+	IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase	E3SNU8	Prochlorococcus_phage	9.8e-45	52.4
SQF43553.1\|45539_46664_-	bacterial SH3 domain protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
SQF43556.1\|46826_48182_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
SQF43558.1\|48460_48952_+	phosphoribosyl carboxyaminoimidazole mutase	A0A2P0VNU7	Tetraselmis_virus	1.9e-18	42.3

DBSCAN-SWA_2

178808 : 222270

Streptococcus_phage(55.56%)

capsid,tRNA,tail,protease,integrase,holin,portal,terminase

attL 177694:177711|attR 222267:222284

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
177694:177711	attL	NA	NA	NA	NA
SQF43764.1\|178808_179951_+\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.9e-86	43.9
SQF43767.1\|180168_180480_+	Helper of Tim protein 13	NA	NA	NA	NA
SQF43768.1\|180483_181023_+	biotin transporter	NA	NA	NA	NA
SQF43769.1\|181162_181942_+	metal-dependent hydrolase	NA	NA	NA	NA
SQF43771.1\|181941_182457_+\|tRNA	tRNA-specific adenosine deaminase	NA	NA	NA	NA
SQF43773.1\|183070_184291_-	S-layer protein	NA	NA	NA	NA
SQF43774.1\|184678_185821_-\|integrase	integrase	A0A141E0H2	Streptococcus_phage	1.4e-117	56.7
SQF43776.1\|185947_186481_-	putative lipoprotein	A0A1S5SAH9	Streptococcus_phage	1.3e-20	55.3
SQF43779.1\|186492_186873_-	phage protein	Q938N7	Temperate_phage	1.4e-40	64.0
SQF43781.1\|186882_187233_-	phage transcriptional regulator, Cro/CI family	A0A1S5SFC6	Streptococcus_phage	4.8e-32	60.3
SQF43783.1\|187543_187759_+	phage protein	M1Q1B4	Streptococcus_phage	2.2e-24	78.6
SQF43785.1\|187832_187967_+	Uncharacterised protein	A3F616	Streptococcus_phage	2.1e-17	100.0
SQF43787.1\|187963_188707_+	phage associated antirepressor	A3F617	Streptococcus_phage	1.5e-120	86.1
SQF43790.1\|188782_188995_+	Uncharacterised protein	NA	NA	NA	NA
SQF43791.1\|189028_189220_+	Uncharacterised protein	NA	NA	NA	NA
SQF43793.1\|189251_189407_+	Uncharacterised protein	NA	NA	NA	NA
SQF43795.1\|189408_189951_-	Uncharacterised protein	NA	NA	NA	NA
SQF43797.1\|190081_190342_+	Uncharacterised protein	A0A1S5SAL2	Streptococcus_phage	1.1e-28	73.3
SQF43799.1\|190360_190549_+	Uncharacterised protein	NA	NA	NA	NA
SQF43801.1\|190535_191882_+	DNA polymerase III delta prime subunit	A0A1P8VVQ6	Streptococcus_phage	7.8e-208	84.7
SQF43803.1\|191868_192471_+	Uncharacterised protein	A0A1P8VVT8	Streptococcus_phage	1.7e-106	93.0
SQF43805.1\|192448_193195_+	DNA replication protein, putative	A0A1P8VVR3	Streptococcus_phage	2.2e-135	96.8
SQF43807.1\|193195_194020_+	phage DNA replication protein	A0A1P8VVV9	Streptococcus_phage	1.4e-127	79.6
SQF43810.1\|194019_194247_+	phage protein	C5J991	Streptococcus_phage	7.1e-13	50.7
SQF43812.1\|194260_194437_+	Uncharacterised protein	NA	NA	NA	NA
SQF43814.1\|194433_194718_+	phage protein	A0A097PAV1	Streptococcus_pyogenes_phage	5.9e-41	93.6
SQF43816.1\|194714_195359_+	modification methylase	A0A140HLV8	Bacillus_phage	1.3e-64	64.6
SQF43818.1\|195346_195502_+	DNA methylase	A0A1S5SFL7	Streptococcus_phage	1.6e-08	60.5
SQF43820.1\|195707_195947_+	DNA methylase	A0A1X9I6Y5	Streptococcus_phage	8.0e-15	61.5
SQF43822.1\|195936_196410_+	gp29	A3F631	Streptococcus_phage	8.0e-91	98.7
SQF43825.1\|196528_196861_+	gp24	A0A1S5SCX1	Streptococcus_phage	1.2e-32	57.4
SQF43826.1\|196853_197183_+	cro/CI family prophage LambdaSa2	A0A1P8VVV5	Streptococcus_phage	3.2e-22	45.5
SQF43827.1\|197179_197353_+	Uncharacterised protein	A0A1J0MGB9	Staphylococcus_phage	1.1e-05	46.9
SQF43829.1\|197355_197604_+	Uncharacterised protein	NA	NA	NA	NA
SQF43832.1\|197600_197780_+	Uncharacterised protein	A0A060QN65	Streptococcus_phage	1.1e-05	55.3
SQF43834.1\|197788_197938_+	Uncharacterised protein	NA	NA	NA	NA
SQF43837.1\|197906_198107_+	Uncharacterised protein	NA	NA	NA	NA
SQF43839.1\|198130_198550_+	RNA polymerase ECF family sigma factor	A0A1S5SF97	Streptococcus_phage	1.1e-19	42.0
SQF43841.1\|198641_199208_+\|integrase	prophage LambdaSa2, site-specific recombinase phage integrase family protein	A0A1S5SCL7	Streptococcus_phage	1.2e-61	61.0
SQF43843.1\|199379_199673_+	Uncharacterised protein	NA	NA	NA	NA
SQF43845.1\|199669_199999_+	HNH endonuclease	A0A1S7FZ53	Listeria_phage	6.7e-20	49.5
SQF43848.1\|200120_200468_+	Uncharacterised protein	E2ELI1	Clostridium_phage	4.0e-07	34.5
SQF43850.1\|200448_202107_+\|terminase	putative phage terminase, large subunit	E2ELI2	Clostridium_phage	4.0e-129	44.4
SQF43852.1\|202305_203541_+\|portal	HK97 family phage portal protein	A0A1S7FYX7	Listeria_phage	3.6e-74	37.6
SQF43854.1\|203544_204261_+\|protease	Prophage Clp protease-like protein	D2XR17	Bacillus_phage	1.4e-38	42.9
SQF43857.1\|204296_205490_+\|capsid	Predicted phage phi-C31 gp36 major capsid-like protein	A0A1B1P752	Bacillus_phage	1.7e-41	30.8
SQF43859.1\|205504_205792_+	HeH/LEM domain	NA	NA	NA	NA
SQF43861.1\|205811_206105_+	Uncharacterised protein	NA	NA	NA	NA
SQF43863.1\|206106_206484_+	Uncharacterised protein	NA	NA	NA	NA
SQF43865.1\|206455_206827_+	Uncharacterised protein	NA	NA	NA	NA
SQF43867.1\|206835_207258_+	Uncharacterised protein	A0A1S7FZ20	Listeria_phage	3.1e-25	48.5
SQF43870.1\|207268_207856_+	Uncharacterised protein	A0A1B1P778	Bacillus_phage	1.1e-28	36.4
SQF43872.1\|207876_208248_+	Uncharacterised protein	NA	NA	NA	NA
SQF43874.1\|208283_208442_+	Uncharacterised protein	NA	NA	NA	NA
SQF43878.1\|208515_211917_+\|tail	tail protein	J7KDT4	Streptococcus_phage	9.5e-93	58.8
SQF43879.1\|211916_212624_+	phage protein	A0A1B1P761	Bacillus_phage	1.3e-28	35.2
SQF43880.1\|212620_214669_+	Phage endopeptidase	Q938K1	Temperate_phage	2.2e-121	44.0
SQF43881.1\|214668_215685_+	phage hyaluronoglucosaminidase	Q938K0	Temperate_phage	3.3e-158	87.0
SQF43882.1\|215700_217716_+	Phage infection protein	Q938J9	Temperate_phage	3.4e-183	75.0
SQF43884.1\|217727_218159_+	phage protein	Q938J8	Temperate_phage	1.1e-73	100.0
SQF43886.1\|218161_218779_+	phage protein	Q938J7	Temperate_phage	2.8e-80	90.2
SQF43887.1\|218788_219244_+\|holin	holin	A0A0M4R3G6	Streptococcus_phage	8.9e-63	80.8
SQF43889.1\|219245_219359_+	phage membrane protein	A7J2B4	Streptococcus_phage	2.6e-08	91.4
SQF43891.1\|219355_220561_+	phage-associated cell wall hydrolase	Q938J4	Temperate_phage	3.1e-208	84.5
SQF43892.1\|220676_221849_-	DNA/RNA non-specific endonuclease family protein	A7J2B8	Streptococcus_phage	1.4e-75	49.5
SQF43894.1\|222087_222270_+	phage protein	A3F673	Streptococcus_phage	1.1e-19	80.0
222267:222284	attR	NA	NA	NA	NA

DBSCAN-SWA_3

364457 : 420569

Streptococcus_phage(33.33%)

transposase,tRNA,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF44181.1\|364457_365048_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
SQF44184.1\|365542_365818_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQF44186.1\|366066_366702_+	thymidylate kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4
SQF44188.1\|366719_367595_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
SQF44190.1\|367613_367853_+	Tpl protein	NA	NA	NA	NA
SQF44194.1\|368256_368580_+	DNA replication initiation control protein	M1PFV3	Streptococcus_phage	1.3e-28	59.4
SQF44196.1\|368584_369448_+	corrin/porphyrin methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
SQF44197.1\|369474_369867_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF44199.1\|369913_370543_-	copper homeostasis protein	NA	NA	NA	NA
SQF44202.1\|370840_371197_+	arsenate reductase	M1PLC0	Streptococcus_phage	4.8e-40	66.7
SQF44205.1\|371270_372098_-	3'-exo-deoxyribonuclease	M1PSC0	Streptococcus_phage	8.4e-128	79.5
SQF44207.1\|372331_373513_+	L-lactate oxidase	NA	NA	NA	NA
SQF44209.1\|373778_378722_+	LPXTG-motif cell wall anchor domain protein	NA	NA	NA	NA
SQF44211.1\|379494_380202_+	permease	NA	NA	NA	NA
SQF44213.1\|380444_382442_+\|tRNA	methionyl-tRNA synthetase	A0A1V0SHR2	Klosneuvirus	6.0e-87	35.2
SQF44216.1\|382935_383949_+	ribonucleotide-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	1.6e-96	53.0
SQF44218.1\|383952_384441_+	nrdI protein	R4JF54	Bacillus_phage	1.3e-11	37.5
SQF44220.1\|384407_386588_+	ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.3e-171	43.2
SQF44222.1\|386790_387543_-	ADP-ribosyltransferase	NA	NA	NA	NA
SQF44225.1\|388000_388351_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF44227.1\|388765_389017_+	hypothetical membrane spanning protein	NA	NA	NA	NA
SQF44229.1\|389110_389383_-	phage protein	NA	NA	NA	NA
SQF44231.1\|389379_389655_-	Uncharacterised protein	NA	NA	NA	NA
SQF44233.1\|389994_390231_+	Protein of uncharacterised function (DUF2829)	NA	NA	NA	NA
SQF44236.1\|390223_390922_+	3-ketoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	5.4e-11	26.0
SQF44238.1\|390997_391957_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
SQF44240.1\|392289_393627_+	phosphoglycerate transporter protein	NA	NA	NA	NA
SQF44243.1\|393800_395183_+	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L4K9	Tupanvirus	6.5e-32	36.0
SQF44246.1\|395216_395771_+	ADP-ribose pyrophosphatase	NA	NA	NA	NA
SQF44248.1\|395770_396022_+	membrane protein	NA	NA	NA	NA
SQF44251.1\|396041_396737_+	MTA/SAH nucleosidase	NA	NA	NA	NA
SQF44253.1\|396887_397229_+	Uncharacterised protein	NA	NA	NA	NA
SQF44255.1\|397327_397975_-	metalloregulator ScaR	NA	NA	NA	NA
SQF44259.1\|398120_399053_+	manganese-binding protein	NA	NA	NA	NA
SQF44262.1\|399116_399842_+	manganese transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
SQF44264.1\|399842_400697_+	ABC 3 transport family protein	NA	NA	NA	NA
SQF44266.1\|400843_401650_-	cyclophilin type peptidyl-prolyl cis-trans isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
SQF44268.1\|401866_404272_+	cell division protein FtsK	S5VNE3	Mycobacterium_phage	2.2e-88	51.4
SQF44271.1\|404341_404695_-	integral membrane protein	NA	NA	NA	NA
SQF44273.1\|404917_406051_+\|transposase	transposase	NA	NA	NA	NA
SQF44276.1\|406055_406160_+	exfoliative toxin	NA	NA	NA	NA
SQF44278.1\|406264_406690_+	50S ribosomal protein L11	NA	NA	NA	NA
SQF44280.1\|406795_407485_+	50S ribosomal protein L1	NA	NA	NA	NA
SQF44283.1\|407806_408535_+	uridylate kinase	NA	NA	NA	NA
SQF44286.1\|408563_409121_+	ribosome recycling factor	NA	NA	NA	NA
SQF44288.1\|409229_410087_+	s1 RNA binding domain	NA	NA	NA	NA
SQF44290.1\|410159_410669_+	methionine sulfoxide reductase A	NA	NA	NA	NA
SQF44292.1\|410665_410881_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQF44293.1\|411036_412218_+	lysM domain protein	A0A0E3XB61	Gordonia_phage	2.1e-15	39.6
SQF44294.1\|412532_414305_+	myosin-cross-reactive antigen	NA	NA	NA	NA
SQF44295.1\|414463_415516_+	phosphate starvation-induced protein	W8D063	Erwinia_phage	1.2e-46	50.0
SQF44297.1\|415561_416137_+	uracil DNA glycosylase superfamily protein	NA	NA	NA	NA
SQF44299.1\|416295_416793_+\|protease	metalloprotease	NA	NA	NA	NA
SQF44301.1\|416773_417181_+	diacylglycerol kinase	NA	NA	NA	NA
SQF44304.1\|417300_418197_+	GTP-binding protein Era	NA	NA	NA	NA
SQF44306.1\|418217_418694_+	phosphohydrolase	NA	NA	NA	NA
SQF44308.1\|419000_419255_-	Uncharacterised protein	NA	NA	NA	NA
SQF44310.1\|419652_419787_+\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQF44312.1\|419899_420082_+\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQF44315.1\|420419_420569_-\|transposase	IS1191 transposase	NA	NA	NA	NA

DBSCAN-SWA_4

512333 : 549943

Streptococcus_phage(65.91%)

holin,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF44571.1\|512333_513182_-	glycosyl hydrolases 25 family protein	A0A223LJI5	Bacillus_phage	1.9e-18	31.3
SQF44573.1\|513506_514010_+	membrane protein	NA	NA	NA	NA
SQF44575.1\|513993_514377_+	Surface-layer 125 kDa protein	NA	NA	NA	NA
SQF44577.1\|514422_514719_-	glutathione peroxidase	NA	NA	NA	NA
SQF44580.1\|514727_516185_-	site-specific recombinase/resolvase	Q38184	Lactococcus_phage	1.5e-132	50.7
SQF44589.1\|516320_516839_-	HIRAN domain protein	E8ZDN5	Streptococcus_phage	7.8e-31	45.3
SQF44592.1\|516850_517606_-	Cro/CI family transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	3.3e-78	61.2
SQF44594.1\|517807_518020_+	helix-turn-helix family protein	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
SQF44596.1\|518060_518192_+	Uncharacterised protein	NA	NA	NA	NA
SQF44598.1\|518188_518371_-	phage membrane protein	NA	NA	NA	NA
SQF44600.1\|518603_518789_+	phage protein	Q938N3	Temperate_phage	1.1e-22	91.8
SQF44603.1\|519277_519667_+	DNA replication protein dnaD	Q938N2	Temperate_phage	8.7e-51	77.5
SQF44605.1\|519647_519881_+	phage protein	Q938N1	Temperate_phage	6.1e-36	94.8
SQF44607.1\|519877_520018_+	phage protein	NA	NA	NA	NA
SQF44609.1\|520026_520233_+	phage protein	NA	NA	NA	NA
SQF44611.1\|520288_520618_+	phage protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
SQF44613.1\|520620_521547_+	recombinase, phage RecT family protein	M1NRN6	Streptococcus_phage	1.2e-90	71.8
SQF44615.1\|521543_521744_+	phage protein	NA	NA	NA	NA
SQF44617.1\|521736_522534_+	phage protein	J7KGZ1	Streptococcus_phage	1.3e-130	83.8
SQF44620.1\|522654_522747_+	phage protein	A0A1S5SCN4	Streptococcus_phage	3.7e-05	70.0
SQF44622.1\|522897_523293_+	phage protein	A8ATL9	Listeria_phage	2.6e-18	51.1
SQF44624.1\|523289_524636_+	PcfJ	A8ATM0	Listeria_phage	1.0e-122	49.4
SQF44626.1\|524646_524979_+	phage protein	M1NS23	Streptococcus_phage	8.8e-36	67.0
SQF44628.1\|524975_525488_+	lactococcus phage M3 family protein	M1PFM2	Streptococcus_phage	5.8e-79	86.5
SQF44630.1\|525523_525838_+	phage protein	A1EAD7	Streptococcus_phage	4.4e-29	71.1
SQF44632.1\|525839_526055_+	phage protein	NA	NA	NA	NA
SQF44634.1\|526051_526303_+	phage protein	M1PF60	Streptococcus_phage	4.8e-18	57.8
SQF44636.1\|526378_526798_+	phage protein	A0A1X9I5B5	Streptococcus_phage	6.7e-57	79.9
SQF44638.1\|526905_527250_+	HNH endonuclease family protein	M1Q0W7	Streptococcus_phage	3.2e-41	69.4
SQF44640.1\|527398_527755_+	phage protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
SQF44643.1\|527751_529020_+	structural phage protein	M1PFL4	Streptococcus_phage	2.2e-188	75.6
SQF44645.1\|529012_530506_+	phage protein	M1Q184	Streptococcus_phage	2.6e-87	54.6
SQF44647.1\|530511_530736_+	phage protein	NA	NA	NA	NA
SQF44649.1\|530812_530965_+	phage protein	NA	NA	NA	NA
SQF44651.1\|530957_531224_+	secreted phage protein	Q938K9	Temperate_phage	6.4e-37	95.5
SQF44653.1\|531543_532959_+\|terminase	phage terminase	A0A0B5A091	Streptococcus_phage	2.9e-213	74.2
SQF44655.1\|533037_533502_+	phage protein	A0A141E167	Streptococcus_phage	5.7e-41	58.4
SQF44657.1\|533505_534399_+	phage structural protein	A0A126GGI3	Streptococcus_phage	1.7e-129	77.7
SQF44659.1\|534400_534529_+	Uncharacterised protein	NA	NA	NA	NA
SQF44661.1\|534549_534972_+	phage Gp19/Gp15/Gp42 family protein	A0A0B5A2F6	Streptococcus_phage	9.7e-48	68.6
SQF44663.1\|534931_535270_+	phage protein	A0A0B5A086	Streptococcus_phage	1.3e-42	68.8
SQF44665.1\|535262_535499_+	phage protein	A0A1P8BMT2	Lactococcus_phage	6.7e-22	67.9
SQF44667.1\|535499_535835_+	phage protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
SQF44670.1\|535850_536432_+\|tail	Major tail protein	M1NS84	Streptococcus_phage	9.9e-59	62.9
SQF44672.1\|536441_536705_+	phage protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
SQF44674.1\|536719_537091_+	phage protein	M1PL84	Streptococcus_phage	1.2e-33	59.2
SQF44675.1\|537090_539448_+	phage protein	M1NRG5	Streptococcus_phage	6.5e-141	50.6
SQF44676.1\|539444_540140_+	phage protein	A0A1B1P761	Bacillus_phage	7.6e-05	29.6
SQF44678.1\|540136_542080_+	phage endopeptidase	M1PKG3	Streptococcus_phage	6.2e-97	50.0
SQF44680.1\|542076_543192_+	phage associated hyaluronidase	A7J2A8	Streptococcus_phage	1.7e-123	71.7
SQF44682.1\|543206_544988_+	gp58-like family protein	Q938J9	Temperate_phage	2.0e-73	42.8
SQF44685.1\|544996_545425_+	phage protein	Q938J8	Temperate_phage	2.8e-66	92.1
SQF44687.1\|545427_546060_+	phage protein	Q938J7	Temperate_phage	3.7e-43	49.5
SQF44689.1\|546069_546525_+\|holin	holin	A0A0M4R3G6	Streptococcus_phage	5.2e-63	81.5
SQF44691.1\|546526_546649_+	phage membrane protein	NA	NA	NA	NA
SQF44693.1\|546636_547845_+	phage-associated cell wall hydrolase	Q938J4	Temperate_phage	2.6e-210	85.6
SQF44695.1\|547923_548151_-	glutathione peroxidase	NA	NA	NA	NA
SQF44697.1\|548143_549943_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	2.9e-109	36.8

DBSCAN-SWA_5

587418 : 679923

107

Streptococcus_phage(56.45%)

capsid,tRNA,tail,protease,integrase,holin,portal,bacteriocin,terminase

attL 592089:592107|attR 632534:632552

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF44750.1\|587418_588765_+\|tRNA	asparaginyl-tRNA synthetase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
SQF44752.1\|589179_590070_+	P-loop ATPase protein family protein	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
SQF44753.1\|590066_591044_+	transporter	A1IMD5	Streptococcus_phage	2.1e-138	74.2
SQF44754.1\|591040_591952_+	sporulation Regulator WhiA C terminal domain-containing protein	Q7AWZ3	Streptococcus_phage	1.3e-105	64.7
592089:592107	attL	NA	NA	NA	NA
SQF44755.1\|592128_593544_-\|integrase	integrase	A5GZ62	Lactococcus_phage	1.4e-109	47.2
SQF44756.1\|593666_593972_-	phage membrane protein	NA	NA	NA	NA
SQF44757.1\|593981_594746_-	phage repressor protein	E8ZDN4	Streptococcus_phage	2.0e-83	64.5
SQF44758.1\|595105_595264_+	phage membrane protein	J7KH24	Streptococcus_phage	7.1e-20	88.5
SQF44760.1\|595362_596004_-	phage protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
SQF44762.1\|596055_596244_+	putative cro protein	A0A0B5A7F0	Streptococcus_phage	2.6e-13	63.3
SQF44764.1\|596292_597054_+	phage antirepressor protein	A0A0C5AEJ9	Bacteriophage	1.6e-85	61.9
SQF44766.1\|597066_597198_+	Uncharacterised protein	NA	NA	NA	NA
SQF44768.1\|597194_597377_-	phage membrane protein	NA	NA	NA	NA
SQF44770.1\|597463_597601_+	phage protein	NA	NA	NA	NA
SQF44772.1\|597602_597788_+	phage protein	Q938N3	Temperate_phage	2.0e-21	83.6
SQF44774.1\|598270_598657_+	phage DNA replication protein	Q938N2	Temperate_phage	2.8e-25	55.0
SQF44776.1\|598637_598871_+	phage protein	Q938N1	Temperate_phage	6.1e-36	94.8
SQF44778.1\|598867_599008_+	phage protein	NA	NA	NA	NA
SQF44780.1\|599016_599223_+	phage protein	NA	NA	NA	NA
SQF44783.1\|599278_599608_+	phage protein	J7KGX3	Streptococcus_phage	2.1e-45	83.5
SQF44785.1\|599610_600537_+	recombinase, phage RecT family protein	M1NRN6	Streptococcus_phage	1.9e-91	69.0
SQF44787.1\|600533_600734_+	phage protein	NA	NA	NA	NA
SQF44789.1\|600726_601524_+	phage protein	J7KGZ1	Streptococcus_phage	6.6e-130	83.8
SQF44791.1\|601700_602042_+	phage protein	M1NS23	Streptococcus_phage	3.1e-12	38.7
SQF44793.1\|602038_602551_+	phage protein	Q708P9	Streptococcus_phage	8.4e-62	73.2
SQF44795.1\|602522_602735_+	phage protein	A3F626	Streptococcus_phage	1.1e-10	86.5
SQF44797.1\|602728_603013_+	phage protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
SQF44799.1\|603009_603279_+	phage protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
SQF44801.1\|603288_603702_+	phage protein	Q938M1	Temperate_phage	6.4e-36	65.2
SQF44803.1\|603698_603983_+	phage protein	A3F628	Streptococcus_phage	4.6e-33	79.8
SQF44805.1\|603986_604472_+	DNA N-4 cytosine methyltransferase M.NgoMXV	A0A097PAU8	Streptococcus_pyogenes_phage	2.0e-92	98.1
SQF44807.1\|604473_605112_+	phage protein	L0P368	Streptococcus_phage	1.3e-80	65.2
SQF44809.1\|605108_605207_+	Uncharacterised protein	NA	NA	NA	NA
SQF44811.1\|605476_605914_+	phage protein	A0A097PBF1	Streptococcus_pyogenes_phage	1.4e-76	99.3
SQF44813.1\|606816_607746_+	phage protein	A0A126HAU2	Lactococcus_phage	4.9e-100	71.8
SQF44815.1\|607872_608250_-	phage protein	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
SQF44817.1\|608301_608487_-	phage protein	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
SQF44819.1\|608585_608726_+	Uncharacterised protein	NA	NA	NA	NA
SQF44821.1\|608722_609061_+	Phage endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
SQF44823.1\|609231_609699_+\|terminase	phage terminase, small subunit	J7KC46	Streptococcus_phage	3.9e-82	98.7
SQF44825.1\|609701_609932_+	Uncharacterised protein	NA	NA	NA	NA
SQF44827.1\|609941_611690_+\|terminase	phage terminase, large subunit	J7KKD1	Streptococcus_phage	0.0e+00	96.2
SQF44829.1\|611686_611857_+	phage protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
SQF44831.1\|611849_612074_+	phage protein	Q938K9	Temperate_phage	3.6e-17	61.4
SQF44833.1\|612107_613328_+\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
SQF44836.1\|613305_613971_+\|protease	phage ClpP protease	M1Q115	Streptococcus_phage	3.5e-92	78.1
SQF44837.1\|613995_615183_+\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
SQF44838.1\|615327_615630_+	phage protein	J7KC36	Streptococcus_phage	1.3e-41	88.8
SQF44839.1\|615626_615974_+	phage protein	J7KJ42	Streptococcus_phage	2.9e-50	88.2
SQF44840.1\|615970_616348_+	phage protein	J7KDM3	Streptococcus_phage	1.8e-45	72.8
SQF44842.1\|616344_616770_+	phage protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
SQF44843.1\|616785_617394_+\|tail	major tail protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
SQF44844.1\|617446_617773_+	phage protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
SQF44845.1\|617982_621906_+\|tail	phage tail protein	J7KDT4	Streptococcus_phage	1.9e-238	48.5
SQF44846.1\|621905_622613_+	phage protein	Q938K2	Temperate_phage	6.8e-94	71.9
SQF44847.1\|622609_624754_+	Phage endopeptidase	Q938K1	Temperate_phage	0.0e+00	94.7
SQF44848.1\|624750_625761_+	phage hyaluronidase	Q938K0	Temperate_phage	7.8e-136	75.8
SQF44849.1\|625773_627660_+	gp58-like family protein	Q938J9	Temperate_phage	3.1e-218	84.7
SQF44850.1\|627671_628103_+	phage protein	Q938J8	Temperate_phage	1.3e-63	89.5
SQF44852.1\|628105_628723_+	phage protein	Q938J7	Temperate_phage	5.0e-77	89.3
SQF44853.1\|628732_629008_+\|holin	phage holin	A7J2B2	Streptococcus_phage	2.6e-41	100.0
SQF44854.1\|629004_629232_+	phage protein	A7J2B3	Streptococcus_phage	5.8e-31	98.7
SQF44855.1\|629347_630553_+	phage-associated cell wall hydrolase	Q938J4	Temperate_phage	1.6e-204	83.3
SQF44856.1\|630620_631328_-	exotoxin type C	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
SQF44857.1\|631438_632197_-	DNA/RNA non-specific endonuclease family protein	NA	NA	NA	NA
SQF44859.1\|632508_633927_+	dipeptidase	NA	NA	NA	NA
632534:632552	attR	NA	NA	NA	NA
SQF44860.1\|634078_635626_+	high-affinity zinc uptake system protein	NA	NA	NA	NA
SQF44861.1\|635775_636498_+	GntR family transcriptional regulator	NA	NA	NA	NA
SQF44862.1\|636517_637717_+	tagatose-6-phosphate ketose/aldose isomerase	NA	NA	NA	NA
SQF44863.1\|637813_638074_-	50S ribosomal protein L31	NA	NA	NA	NA
SQF44865.1\|638188_639130_-	DHH family protein	NA	NA	NA	NA
SQF44866.1\|639523_639973_+	flavodoxin	NA	NA	NA	NA
SQF44867.1\|640147_640432_+	chorismate mutase	NA	NA	NA	NA
SQF44868.1\|640424_641687_+	chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	3.2e-94	50.5
SQF44869.1\|641801_642149_+	50S ribosomal protein L19	NA	NA	NA	NA
SQF44871.1\|643164_643734_+	hydrolase, haloacid dehalogenase-like family	NA	NA	NA	NA
SQF44872.1\|643734_645687_+	DNA gyrase subunit B	G3M9Z3	Bacillus_virus	1.5e-143	46.2
SQF44875.1\|646054_647779_+	septation ring formation regulator	NA	NA	NA	NA
SQF44877.1\|647910_648369_-	hypothetical cytosolic protein	W6LLD2	Streptococcus_phage	2.3e-18	39.1
SQF44879.1\|648595_649903_+	Enolase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
SQF44882.1\|650672_650834_+\|bacteriocin	bacteriocin protoxin, streptolysin S family protein	NA	NA	NA	NA
SQF44884.1\|651055_652006_+	sagB-type dehydrogenase domain-containing protein	NA	NA	NA	NA
SQF44886.1\|652002_653061_+\|bacteriocin	bacteriocin biosynthesis cyclodehydratase	NA	NA	NA	NA
SQF44889.1\|653080_654439_+\|bacteriocin	bacteriocin biosynthesis docking scaffold, SagD family domain-containing protein	NA	NA	NA	NA
SQF44892.1\|654413_655085_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
SQF44895.1\|655081_655765_+	streptolysin S biosynthesis protein SagF	NA	NA	NA	NA
SQF44898.1\|655787_656711_+	ABC transporter family protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-33	31.4
SQF44899.1\|656719_657847_+	ABC transporter	NA	NA	NA	NA
SQF44900.1\|657843_658962_+	ABC transporter	NA	NA	NA	NA
SQF44901.1\|659533_662266_+	LPXTG-motif cell wall anchor domain-containing protein	NA	NA	NA	NA
SQF44903.1\|663237_665196_+	NAD-dependent DNA ligase	A0A0K2QQN8	Ralstonia_phage	7.6e-103	34.9
SQF44905.1\|665209_666232_+	lipid kinase	A0A1V0SBJ0	Catovirus	3.6e-19	27.9
SQF44907.1\|666622_666820_+	F0F1 ATP synthase subunit C	NA	NA	NA	NA
SQF44909.1\|666854_667571_+	F0F1 ATP synthase subunit A	NA	NA	NA	NA
SQF44912.1\|667588_668083_+	F0F1 ATP synthase subunit B	NA	NA	NA	NA
SQF44914.1\|668082_668619_+	ATP synthase delta chain	NA	NA	NA	NA
SQF44918.1\|668634_670143_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
SQF44920.1\|670158_671034_+	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
SQF44923.1\|671195_672602_+	ATP synthase F0F1 subunit beta	NA	NA	NA	NA
SQF44925.1\|672614_673031_+	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
SQF44928.1\|673296_673554_+	membrane protein	NA	NA	NA	NA
SQF44931.1\|673618_674890_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
SQF44934.1\|674893_675082_+	epuA protein	NA	NA	NA	NA
SQF44938.1\|675144_675696_+	DNA-entry nuclease	NA	NA	NA	NA
SQF44940.1\|675682_675982_+	DNA-entry nuclease	NA	NA	NA	NA
SQF44943.1\|676264_677308_+\|tRNA	phenylalanyl-tRNA synthetase alpha subunit	A0A2K9L3A8	Tupanvirus	3.5e-30	34.3
SQF44945.1\|677517_679923_+\|tRNA	phenylalanyl-tRNA synthetase subunit beta	NA	NA	NA	NA

DBSCAN-SWA_6

715332 : 725935

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF45014.1\|715332_717543_-	phosphoglycerol transferase	W6LM83	Streptococcus_phage	7.7e-269	69.2
SQF45015.1\|717650_718814_+	SAM-dependent methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
SQF45017.1\|718810_719497_+	3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
SQF45020.1\|719590_720757_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
SQF45021.1\|720817_721159_+	hypothetical cytosolic protein	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	40.2
SQF45022.1\|721379_722732_+	glutathione reductase	A0A2K5B2C5	Erysipelothrix_phage	4.5e-30	24.0
SQF45023.1\|722819_723764_-	folylpolyglutamate synthase	NA	NA	NA	NA
SQF45024.1\|723797_724088_-	folylpolyglutamate synthase	NA	NA	NA	NA
SQF45027.1\|724117_724558_-	membrane protein	NA	NA	NA	NA
SQF45030.1\|724792_725935_+	aminotransferase class-V family protein	A0A1X6WFP1	Pacmanvirus	4.1e-24	27.0

DBSCAN-SWA_7

752901 : 787784

Bacillus_phage(30.77%)

head,transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF45089.1\|752901_753633_+\|tRNA	tRNA (guanine-N(1)-)-methyltransferase	NA	NA	NA	NA
SQF45091.1\|753632_754625_+	thioredoxin reductase	Q9JRK7	Streptococcus_phage	1.4e-28	54.9
SQF45094.1\|754802_755861_+	regulatory protein	NA	NA	NA	NA
SQF45096.1\|755873_756797_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
SQF45098.1\|757052_757766_+	deoR-like helix-turn-helix domain-containing protein	A0A077SK06	Escherichia_phage	5.5e-19	31.7
SQF45100.1\|757762_758674_+	1-phosphofructokinase	NA	NA	NA	NA
SQF45102.1\|758670_760617_+	PTS system fructose-specific transporter subunit IIABC	NA	NA	NA	NA
SQF45104.1\|760715_761309_+	N-acetylmuramidase	A0A249Y0X5	Enterococcus_phage	2.7e-11	33.8
SQF45106.1\|761460_762168_+	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q332B8	Clostridium_botulinum_C_phage	6.5e-12	36.4
SQF45108.1\|762224_762443_-\|transposase	degenerate transposase	A0A1B1P773	Bacillus_phage	2.7e-09	55.9
SQF45110.1\|763124_764150_-\|protease	igG-degrading protease	NA	NA	NA	NA
SQF45112.1\|764653_764830_+	nucleoside diphosphate kinase	NA	NA	NA	NA
SQF45114.1\|765057_765438_+\|transposase	transposase	NA	NA	NA	NA
SQF45116.1\|765437_766286_+	degV family protein	NA	NA	NA	NA
SQF45118.1\|766410_767619_+\|head	poly A polymerase head domain-containing protein	H7BUW3	unidentified_phage	6.9e-38	45.0
SQF45120.1\|767615_769493_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.3e-62	31.1
SQF45123.1\|770384_770795_+	polypeptide deformylase family protein	E3SLL2	Synechococcus_phage	6.9e-06	30.6
SQF45125.1\|770875_772888_-	5'-nucleotidase	NA	NA	NA	NA
SQF45127.1\|773108_773759_+	GTP pyrophosphokinase	NA	NA	NA	NA
SQF45129.1\|773761_774430_+	two-component response regulator	W8CYM9	Bacillus_phage	2.3e-19	28.8
SQF45131.1\|774438_775671_+	two component system histidine kinase	NA	NA	NA	NA
SQF45134.1\|775964_776843_+	mevalonate kinase	NA	NA	NA	NA
SQF45135.1\|776824_777769_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
SQF45137.1\|777761_778775_+	phosphomevalonate kinase	NA	NA	NA	NA
SQF45139.1\|778761_779751_+	isopentenyl pyrophosphate isomerase	NA	NA	NA	NA
SQF45142.1\|779980_781258_-	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
SQF45144.1\|781244_782420_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
SQF45147.1\|782628_783468_+	thymidylate synthase	U5J9N5	Bacillus_phage	2.4e-82	52.9
SQF45149.1\|783547_784045_+	dihydrofolate reductase	W5QU76	Bacillus_phage	8.6e-11	34.4
SQF45152.1\|784064_784235_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQF45154.1\|784364_785594_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	7.8e-138	60.5
SQF45156.1\|785603_786203_+	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
SQF45159.1\|786350_787094_+	virulence factor relevant regulator	NA	NA	NA	NA
SQF45161.1\|787151_787784_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A248SJW6	Salicola_phage	3.2e-34	39.4

DBSCAN-SWA_8

1059296 : 1144173

108

Streptococcus_phage(39.06%)

transposase,tail,head,holin,integrase,portal,terminase

attL 1060332:1060391|attR 1106153:1106248

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF45635.1\|1059296_1059911_-	membrane protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
1060332:1060391	attL	NA	NA	NA	NA
SQF45637.1\|1060501_1060690_-	paratox	A3F673	Streptococcus_phage	1.3e-20	83.1
SQF45639.1\|1060927_1061728_+	streptodornase	NA	NA	NA	NA
SQF45641.1\|1061998_1062124_+	phage membrane protein	NA	NA	NA	NA
SQF45643.1\|1062503_1063709_-	phage-associated cell wall hydrolase	Q938J4	Temperate_phage	2.7e-207	84.5
SQF45645.1\|1063705_1063816_-	phage membrane protein	A7J2B4	Streptococcus_phage	3.0e-09	94.4
SQF45647.1\|1063824_1064052_-	phage protein	A7J2B3	Streptococcus_phage	2.0e-31	100.0
SQF45649.1\|1064048_1064324_-\|holin	phage holin	A7J2B2	Streptococcus_phage	2.6e-41	100.0
SQF45652.1\|1064333_1064951_-	phage protein	Q938J7	Temperate_phage	1.4e-79	89.3
SQF45654.1\|1064953_1065115_-	phage protein	NA	NA	NA	NA
SQF45655.1\|1065128_1067039_-	phage infection protein	Q938J9	Temperate_phage	6.0e-121	71.3
SQF45658.1\|1067051_1068059_-	phage hyaluronidase	A7J2A8	Streptococcus_phage	1.4e-137	71.7
SQF45660.1\|1068055_1070107_-	phage protein	A3F656	Streptococcus_phage	0.0e+00	84.3
SQF45662.1\|1070103_1070883_-\|tail	phage tail protein	A3F655	Streptococcus_phage	1.9e-68	55.5
SQF45664.1\|1070914_1074181_-	tape measure domain protein	U6E979	Streptococcus_phage	1.6e-04	30.4
SQF45666.1\|1074195_1074525_-	phage protein	A0A1P8BLR3	Lactococcus_phage	2.0e-11	41.5
SQF45667.1\|1074566_1074926_-	phage protein	D7RWD6	Brochothrix_phage	4.3e-20	44.5
SQF45668.1\|1074978_1075581_-\|tail	phage major tail protein	D7RWD5	Brochothrix_phage	1.3e-40	52.0
SQF45669.1\|1075636_1076026_-	phage protein	Q38611	Lactococcus_phage	3.5e-44	68.2
SQF45671.1\|1076022_1076379_-	phage protein	A0A097BY98	Enterococcus_phage	5.7e-17	46.3
SQF45672.1\|1076368_1076677_-	phage protein	A0A2P1JTW8	Anoxybacillus_phage	5.7e-13	40.2
SQF45673.1\|1076673_1077027_-	phage protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
SQF45674.1\|1077040_1077283_-	phage protein	NA	NA	NA	NA
SQF45676.1\|1077292_1078369_-\|head	phage head protein	A0A2H4J022	uncultured_Caudovirales_phage	5.5e-103	56.0
SQF45677.1\|1078368_1078749_-	structural protein	A0A0K2CNR0	Brevibacillus_phage	5.2e-08	37.9
SQF45679.1\|1078758_1079292_-	phage protein	A0A141E0S7	Streptococcus_phage	1.4e-14	83.9
SQF45681.1\|1079403_1080147_-	antirepressor	M1PKL6	Streptococcus_phage	5.3e-73	56.9
SQF45683.1\|1080148_1080397_-	Uncharacterised protein	NA	NA	NA	NA
SQF45685.1\|1080511_1080691_-	Uncharacterised protein	M1NRK8	Streptococcus_phage	2.6e-18	79.7
SQF45687.1\|1080786_1081056_-	phage protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.3e-34	84.1
SQF45689.1\|1081115_1081295_-	Uncharacterised protein	NA	NA	NA	NA
SQF45691.1\|1081285_1082911_-\|head	phage head morphogenesis, SPP1 gp7 family domain protein	U6E9F1	Streptococcus_phage	1.1e-46	43.8
SQF45693.1\|1082891_1084394_-\|portal	phage portal protein, SPP1 family	C9W9H5	Streptococcus_virus	1.9e-141	54.5
SQF45695.1\|1084405_1085713_-\|terminase	terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	8.5e-183	75.0
SQF45698.1\|1085690_1086122_-\|terminase	terminase	A0A1S5SCD2	Streptococcus_phage	2.2e-47	69.9
SQF45700.1\|1086220_1086406_+	phage protein	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
SQF45702.1\|1086457_1086835_+	phage protein	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
SQF45704.1\|1086973_1087435_-	Uncharacterised protein	NA	NA	NA	NA
SQF45707.1\|1087453_1088368_-	phage protein	NA	NA	NA	NA
SQF45709.1\|1089289_1089727_-	phage protein	A0A097PBF1	Streptococcus_pyogenes_phage	3.6e-77	100.0
SQF45711.1\|1089995_1090631_-	phage protein	L0P368	Streptococcus_phage	5.5e-87	67.9
SQF45713.1\|1090630_1091032_-	Uncharacterised protein	NA	NA	NA	NA
SQF45715.1\|1091222_1091705_-	DNA N-4 cytosine methyltransferase M.NgoMXV	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
SQF45717.1\|1091708_1092068_-	phage protein	A0A097PAV1	Streptococcus_pyogenes_phage	5.4e-39	88.5
SQF45718.1\|1092193_1092463_-	phage protein	Q938M2	Temperate_phage	2.5e-41	87.6
SQF45720.1\|1092459_1092744_-	phage protein	A0A1P8VVP5	Streptococcus_phage	2.0e-49	98.9
SQF45722.1\|1092737_1092974_-	phage protein	A0A1P8VVV4	Streptococcus_phage	2.9e-33	83.1
SQF45724.1\|1092970_1093327_-	phage protein	A0A097PAU4	Streptococcus_pyogenes_phage	5.1e-58	95.8
SQF45726.1\|1093310_1093661_-	phage protein	A0A1P8VVL5	Streptococcus_phage	2.6e-46	89.4
SQF45728.1\|1093614_1094484_-	phage protein	A0A1P8BME8	Lactococcus_phage	3.7e-102	64.9
SQF45730.1\|1094750_1096304_-	bacteriophage resistance protein	A0A1P8BM51	Lactococcus_phage	4.3e-210	70.4
SQF45732.1\|1096321_1096804_-	phage protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
SQF45734.1\|1096808_1098173_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	3.8e-194	72.3
SQF45736.1\|1098247_1098931_-	phage protein	J7KC09	Streptococcus_phage	9.4e-125	99.1
SQF45738.1\|1098927_1099212_-	phage protein	NA	NA	NA	NA
SQF45740.1\|1099208_1099403_-	phage protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
SQF45742.1\|1099402_1099732_-	phage protein	A1EAC2	Streptococcus_phage	2.7e-13	41.6
SQF45744.1\|1099715_1099829_-	Uncharacterised protein	A0A097PAT6	Streptococcus_pyogenes_phage	7.6e-08	75.0
SQF45746.1\|1099812_1099950_-	phage protein	A0A097PAR2	Streptococcus_pyogenes_phage	4.9e-17	97.8
SQF45748.1\|1099946_1100243_-	phage protein	A0A097PAT8	Streptococcus_pyogenes_phage	4.6e-44	86.7
SQF45750.1\|1100320_1100506_-	phage protein	J7KH19	Streptococcus_phage	1.2e-18	70.5
SQF45752.1\|1100649_1100868_+	Uncharacterised protein	NA	NA	NA	NA
SQF45754.1\|1100853_1100985_-	Uncharacterised protein	NA	NA	NA	NA
SQF45756.1\|1101040_1101250_+	phage protein	NA	NA	NA	NA
SQF45758.1\|1101208_1101454_-	phage protein	A0A097PAP6	Streptococcus_pyogenes_phage	1.2e-34	95.1
SQF45760.1\|1101508_1102018_+	phage protein	NA	NA	NA	NA
SQF45762.1\|1102125_1102353_-	phage protein	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
SQF45763.1\|1102426_1102909_+	Uncharacterised protein	NA	NA	NA	NA
SQF45765.1\|1102905_1103052_-	Uncharacterised protein	NA	NA	NA	NA
SQF45766.1\|1103212_1103950_+	phage transcriptional repressor	A0A1S5S8T5	Streptococcus_phage	2.7e-77	63.9
SQF45767.1\|1103962_1104772_+	phage protein	J7KDP1	Streptococcus_phage	3.8e-24	35.8
SQF45768.1\|1105021_1106110_+\|integrase	integrase	A0A097PAS9	Streptococcus_pyogenes_phage	4.2e-204	99.4
SQF45769.1\|1106472_1107093_+	phage protein	NA	NA	NA	NA
1106153:1106248	attR	NA	NA	NA	NA
SQF45770.1\|1107349_1109614_-	glycogen phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
SQF45771.1\|1109648_1111142_-	4-alpha-glucanotransferase	NA	NA	NA	NA
SQF45772.1\|1111256_1112276_-	LacI family transcription regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
SQF45773.1\|1112519_1113767_+	maltose/maltodextrin-binding protein	NA	NA	NA	NA
SQF45775.1\|1114040_1115402_+	maltose/maltodextrin ABC transport system permease	NA	NA	NA	NA
SQF45776.1\|1115401_1116238_+	maltose transport system permease	NA	NA	NA	NA
SQF45777.1\|1116611_1117199_+\|transposase	truncated transposase	Q9MBM9	Staphylococcus_prophage	3.5e-27	39.1
SQF45778.1\|1117712_1118696_-	alpha/beta fold family hydrolase	NA	NA	NA	NA
SQF45779.1\|1118726_1119977_-	D-alanine transfer from undecaprenol-phosphate to the poly(Glycerophosphate) chain	NA	NA	NA	NA
SQF45780.1\|1119969_1120209_-	D-alanine-poly(phosphoribitol) ligase subunit 2	NA	NA	NA	NA
SQF45782.1\|1120226_1121483_-	Protein dltB	NA	NA	NA	NA
SQF45783.1\|1121479_1123018_-	D-alanine--poly(phosphoribitol) ligase subunit 1	A0A2K9KZV5	Tupanvirus	5.0e-41	28.2
SQF45784.1\|1123029_1123173_-	D-alanyl-lipoteichoic acid biosynthesis protein DltX	NA	NA	NA	NA
SQF45785.1\|1123436_1125428_-	excinuclease ABC subunit B	NA	NA	NA	NA
SQF45786.1\|1125620_1127795_+	glutamine-binding protein/glutamine transpor tsystem permease protein	NA	NA	NA	NA
SQF45787.1\|1127794_1128535_+	glutamine transport ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	1.5e-35	42.1
SQF45788.1\|1128682_1128805_-	Uncharacterised protein	NA	NA	NA	NA
SQF45790.1\|1128830_1130210_-	PTS system cellobiose-specific transporter subunit IIC	NA	NA	NA	NA
SQF45791.1\|1130400_1130835_-	Domain of uncharacterised function (DUF3284)	NA	NA	NA	NA
SQF45792.1\|1130831_1131167_-	PTS system cellobiose-specific transporter subunit IIA	NA	NA	NA	NA
SQF45793.1\|1131169_1131481_-	PTS system cellobiose-specific component IIB	NA	NA	NA	NA
SQF45794.1\|1131503_1133498_-	PTS system mannitol (cryptic)-specific transporter subunit IIA	NA	NA	NA	NA
SQF45795.1\|1133603_1134698_-	outer surface protein	NA	NA	NA	NA
SQF45796.1\|1134706_1136107_-	beta-glucosidase	NA	NA	NA	NA
SQF45798.1\|1136331_1137027_+	nicotinamide mononucleotide transporter	NA	NA	NA	NA
SQF45799.1\|1137031_1137190_-	hypothetical cytosolic protein	NA	NA	NA	NA
SQF45800.1\|1137258_1138572_-	GTPase ObgE	NA	NA	NA	NA
SQF45801.1\|1138628_1138757_-	membrane protein	NA	NA	NA	NA
SQF45802.1\|1138998_1139514_+\|transposase	transposase	NA	NA	NA	NA
SQF45803.1\|1139534_1140341_+\|transposase	transposase, IS861	A0A1B1P773	Bacillus_phage	1.1e-63	50.0
SQF45804.1\|1140640_1141513_-	nicotinate-nucleotide pyrophosphorylase	NA	NA	NA	NA
SQF45806.1\|1141736_1143047_+	membrane protein	NA	NA	NA	NA
SQF45807.1\|1143124_1143418_+\|transposase	transposase	NA	NA	NA	NA
SQF45808.1\|1143450_1143804_+	DNA-binding protein	A0A0C5AEB1	Paenibacillus_phage	1.6e-06	30.8
SQF45809.1\|1143849_1144173_+\|transposase	transposase	A0A1P8CWQ3	Bacillus_phage	3.3e-19	46.2

DBSCAN-SWA_9

1402679 : 1471788

Streptococcus_phage(78.18%)

tRNA,tail,holin,integrase,portal,terminase

attL 1431679:1431695|attR 1471834:1471850

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF46363.1\|1402679_1404719_-\|tRNA	glycyl-tRNA synthetase subunit beta	NA	NA	NA	NA
SQF46365.1\|1405095_1406013_-\|tRNA	glycyl-tRNA synthetase alpha subunit	NA	NA	NA	NA
SQF46368.1\|1406383_1406917_-	hypothetical membrane spanning protein	NA	NA	NA	NA
SQF46370.1\|1407048_1407888_-	2,5-diketo-D-gluconic acid reductase	A0A2H4PQR8	Staphylococcus_phage	2.5e-50	40.3
SQF46372.1\|1408009_1409158_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
SQF46374.1\|1409275_1410907_-	Sodium-dependent phosphate transporter	A0A1B1ITU5	uncultured_Mediterranean_phage	2.7e-05	38.8
SQF46376.1\|1411108_1411831_+	lipoprotein	NA	NA	NA	NA
SQF46377.1\|1411959_1412802_-	EDD, DegV family domain-containing protein	A0A1X9I5J4	Streptococcus_phage	1.3e-91	61.9
SQF46379.1\|1413094_1413652_+	TetR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.2e-14	60.3
SQF46381.1\|1413687_1414512_-	haloacid dehalogenase	NA	NA	NA	NA
SQF46383.1\|1414513_1415131_-	HAD superfamily hydrolase	NA	NA	NA	NA
SQF46385.1\|1415149_1415239_-	Uncharacterised protein	NA	NA	NA	NA
SQF46388.1\|1415327_1416305_-	tagatose 1,6-diphosphate aldolase	NA	NA	NA	NA
SQF46390.1\|1416386_1416650_-	tagatose-6-phosphate kinase	NA	NA	NA	NA
SQF46391.1\|1416814_1417330_-	galactose-6-phosphate isomerase subunit	NA	NA	NA	NA
SQF46393.1\|1417344_1417770_-	galactose-6-phosphate isomerase subunit	A0A222YX14	Synechococcus_phage	4.9e-07	28.6
SQF46395.1\|1418026_1419478_-	PTS system galactitol-specific family transporter subunit IIC	NA	NA	NA	NA
SQF46397.1\|1419503_1419809_-	PTS system galactose-specific transporter subunit IIB	NA	NA	NA	NA
SQF46399.1\|1419801_1420275_-	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 family protein	NA	NA	NA	NA
SQF46401.1\|1420511_1421282_+	lactose phosphotransferase system repressor	A0A077SK06	Escherichia_phage	6.4e-21	27.8
SQF46403.1\|1421485_1421689_-	copper chaperone	NA	NA	NA	NA
SQF46405.1\|1421702_1423934_-	copper-exporting ATPase	A0A218MNH6	uncultured_virus	2.9e-114	37.5
SQF46407.1\|1423933_1424368_-	copAB ATPase metal-fist type repressor	NA	NA	NA	NA
SQF46409.1\|1424539_1425529_+	esterase / lipase	NA	NA	NA	NA
SQF46411.1\|1425659_1426010_-	truncated ribosome-binding factor A	NA	NA	NA	NA
SQF46413.1\|1426215_1429077_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	4.5e-19	25.2
SQF46415.1\|1429096_1429399_-	ribosomal protein in infB 5'region	NA	NA	NA	NA
SQF46417.1\|1429391_1429688_-	putative cytoplasmic protein	NA	NA	NA	NA
SQF46419.1\|1429703_1430849_-	transcription elongation factor	NA	NA	NA	NA
SQF46421.1\|1431035_1431572_-	ribosome maturation factor rimP	NA	NA	NA	NA
1431679:1431695	attL	NA	NA	NA	NA
SQF46423.1\|1431816_1431996_-	paratox	A3F673	Streptococcus_phage	5.2e-19	79.7
SQF46425.1\|1432062_1432857_-	streptococcal phage DNAse	A7J2B8	Streptococcus_phage	8.9e-26	35.6
SQF46427.1\|1433101_1434316_-	N-acetylmuramoyl-L-alanine amidase	A0A1P8VVM5	Streptococcus_phage	9.7e-165	60.5
SQF46429.1\|1434312_1434426_-	phage membrane protein	A7J2B4	Streptococcus_phage	2.2e-07	82.9
SQF46431.1\|1434427_1434883_-\|holin	holin	A0A0M4R3G6	Streptococcus_phage	3.0e-63	81.5
SQF46433.1\|1434893_1435526_-	phage protein	Q938J7	Temperate_phage	4.3e-47	51.9
SQF46436.1\|1435528_1435960_-	phage protein	Q938J8	Temperate_phage	1.3e-63	89.5
SQF46438.1\|1435971_1437990_-	Phage infection protein	Q938J9	Temperate_phage	2.7e-172	69.5
SQF46440.1\|1438002_1439124_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.6e-126	71.2
SQF46442.1\|1439123_1441163_-	phage protein	A7J2A7	Streptococcus_phage	0.0e+00	91.0
SQF46444.1\|1441172_1442015_-	phage protein	A7J2A6	Streptococcus_phage	5.5e-159	98.6
SQF46446.1\|1442239_1446052_-\|tail	phage minor tail protein	A7J2A5	Streptococcus_phage	5.2e-241	98.9
SQF46448.1\|1446066_1446300_-	phage protein	A7J2A4	Streptococcus_phage	4.4e-34	100.0
SQF46450.1\|1446374_1446830_-	phage protein	A7J2A3	Streptococcus_phage	8.3e-77	100.0
SQF46452.1\|1446883_1447483_-\|tail	phage major tail protein	A7J2A2	Streptococcus_phage	2.2e-93	100.0
SQF46454.1\|1447494_1447854_-	phage protein	A7J2A1	Streptococcus_phage	2.1e-59	100.0
SQF46456.1\|1447960_1448200_-	phage protein	A7J2A0	Streptococcus_phage	1.7e-33	94.9
SQF46458.1\|1448196_1448475_-	phage protein	A7J299	Streptococcus_phage	4.2e-47	98.9
SQF46460.1\|1448485_1448842_-	phage protein	A7J298	Streptococcus_phage	2.5e-57	98.3
SQF46462.1\|1448853_1449741_-	phage protein	A7J297	Streptococcus_phage	2.1e-161	100.0
SQF46464.1\|1449753_1450323_-	phage protein	A7J296	Streptococcus_phage	1.0e-79	97.4
SQF46466.1\|1450483_1450750_-	phage protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.1e-33	85.2
SQF46468.1\|1450752_1450869_-	phage membrane protein	A7J294	Streptococcus_phage	3.0e-07	97.4
SQF46470.1\|1450971_1452417_-	phage protein	A7J293	Streptococcus_phage	4.5e-270	96.7
SQF46473.1\|1452376_1453909_-\|portal	phage portal protein	A7J292	Streptococcus_phage	4.3e-287	98.2
SQF46474.1\|1453923_1455201_-\|terminase	terminase large subunit	A7J291	Streptococcus_phage	3.5e-242	98.1
SQF46476.1\|1455190_1455643_-\|terminase	phage terminase small subunit	A7J290	Streptococcus_phage	1.0e-71	93.3
SQF46478.1\|1455738_1456152_-	phage protein	A7J289	Streptococcus_phage	5.8e-45	64.2
SQF46480.1\|1456284_1456551_-	phage protein	A7J287	Streptococcus_phage	7.3e-17	60.0
SQF46482.1\|1456553_1456715_-	phage protein	A7J285	Streptococcus_phage	1.2e-22	94.3
SQF46484.1\|1456715_1458038_-	SNF2 family phage protein	A7J284	Streptococcus_phage	4.6e-253	98.0
SQF46486.1\|1458034_1458310_-	phage protein	A7J283	Streptococcus_phage	8.6e-45	96.7
SQF46487.1\|1458676_1461061_-	phage DNA primase/helicase protein	A7J282	Streptococcus_phage	8.8e-287	97.6
SQF46488.1\|1461065_1462997_-	phage DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	87.8
SQF46489.1\|1463039_1463603_-	phage protein	D2J040	Enterococcus_phage	7.4e-51	57.9
SQF46490.1\|1463616_1464774_-	phage protein	A7J278	Streptococcus_phage	1.7e-219	99.7
SQF46491.1\|1464773_1465073_-	phage protein	A7J277	Streptococcus_phage	1.0e-38	92.9
SQF46492.1\|1465160_1465364_-	phage protein	A7J276	Streptococcus_phage	9.4e-33	100.0
SQF46493.1\|1465360_1465513_-	phage protein	A7J275	Streptococcus_phage	4.4e-19	100.0
SQF46494.1\|1465509_1465893_-	phage protein	A7J274	Streptococcus_phage	7.2e-66	100.0
SQF46496.1\|1465889_1466096_-	phage protein	NA	NA	NA	NA
SQF46497.1\|1466088_1466259_-	phage protein	A7J273	Streptococcus_phage	2.0e-20	89.3
SQF46498.1\|1466255_1466531_-	phage protein	A7J272	Streptococcus_phage	1.7e-45	95.6
SQF46500.1\|1466589_1466799_-	phage protein	M1Q1B4	Streptococcus_phage	7.7e-14	53.6
SQF46501.1\|1467090_1467438_+	Cro/CI family phage transcriptional regulator	A0A126GGQ7	Streptococcus_phage	1.5e-41	73.5
SQF46504.1\|1467441_1467828_+	peptidase	Q7Y4M1	Streptococcus_phage	1.3e-38	58.4
SQF46506.1\|1467952_1469674_+	prophage Lp2 protein 4	NA	NA	NA	NA
SQF46508.1\|1469730_1470588_+	Site-specific DNA methylase	A0A2H4UUI2	Bodo_saltans_virus	9.9e-15	29.3
SQF46510.1\|1470708_1471788_+\|integrase	integrase	A7J266	Streptococcus_phage	7.5e-177	93.3
1471834:1471850	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage