CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483357	Streptococcus pyogenes strain NCTC8326 genome assembly, chromosome: 1	1 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csn2,cas9,csm6,DinG,csa3	1	4	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483357_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483357_1

562575-562935

TypeI

I-C

Consensus_repeat	Method
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRT

5 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of LS483357_1

>merge|LS483357|1|562575-562935|PILER-CR,CRISPRCasFinder,CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAATTACTAGCGTTGAGATAGCCGGTATTAATCTTACCGTCTCACCCTTCATGGGTGAGTGGATTGAAATATTTCGTCACCTCCTCAATCAATAATAGAGTCAGTCTCACCCTTCATGGGTGAGTGGATTGAAATCTAAGATGATACCAGTTACAATACCGATTTTAAGCGTCTCACCCTTCATGGGTGAGTGGATTGAAATAAATAATTACATGACTAGCCAATACACCCACATAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTTCATGAGCTTCTTTACTCTCAAAGTAAGAGTGGTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>LS483357|1|1|562575-562935|PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TACTAGCGTTGAGATAGCCGGTATTAATCTTACC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATTTCGTCACCTCCTCAATCAATAATAGAGTCA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CTAAGATGATACCAGTTACAATACCGATTTTAAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>LS483357|1|1|562575-562935|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TACTAGCGTTGAGATAGCCGGTATTAATCTTACC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATTTCGTCACCTCCTCAATCAATAATAGAGTCA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CTAAGATGATACCAGTTACAATACCGATTTTAAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>LS483357|1|1|562575-562935|CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TACTAGCGTTGAGATAGCCGGTATTAATCTTACC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATTTCGTCACCTCCTCAATCAATAATAGAGTCA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CTAAGATGATACCAGTTACAATACCGATTTTAAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
LS483357.1\|SQF57059.1\|554815_556444_+\|ATP-dependent-RNA-helicase	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
LS483357.1\|SQF57066.1\|562132_562426_+\|hypothetical-cytosolic-protein	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
LS483357.1\|SQF57070.1\|565677_566418_+\|two-component-response-regulator	unknown	unknown	gnl\|CDD\|227095
LS483357.1\|SQF57063.1\|559575_560424_+\|putative-cytoplasmic-protein	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
LS483357.1\|SQF57069.1\|564483_565590_+\|bifunctional-methionine-sulfoxide-reductase-A/B	unknown	unknown	gnl\|CDD\|184456
LS483357.1\|SQF57065.1\|561096_562122_+\|DNA-polymerase	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
LS483357.1\|SQF57067.1\|563094_563805_+\|cytochrome-c-type-biogenesis-protein	unknown	unknown	gnl\|CDD\|223856
LS483357.1\|SQF57072.1\|568220_569300_+\|cytoplasmic-protein	unknown	unknown	gnl\|CDD\|225197
LS483357.1\|SQF57071.1\|566414_568148_+\|two-component-sensor-kinase	unknown	unknown	gnl\|CDD\|225519
LS483357.1\|SQF57060.1\|556521_556815_+\|ATP-dependent-RNA-helicase	unknown	unknown	unknown
LS483357.1\|SQF57073.1\|569313_570030_+\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
LS483357.1\|SQF57061.1\|556947_557676_+\|CRISPR-associated-protein-cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
LS483357.1\|SQF57074.1\|570196_570670_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
LS483357.1\|SQF57075.1\|570811_571492_+\|Fumarate-and-nitrate-reduction-regulatory-protein	unknown	unknown	gnl\|CDD\|223736
LS483357.1\|SQF57068.1\|563817_564441_+\|disulfide-interchange-protein	unknown	unknown	gnl\|CDD\|239264
LS483357.1\|SQF57064.1\|560425_561100_+\|RecB-family-exonuclease	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
LS483357.1\|SQF57058.1\|552013_554662_+\|valyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|235582
LS483357.1\|SQF57057.1\|551448_552012_+\|shikimate-kinase	unknown	unknown	gnl\|CDD\|223637
LS483357.1\|SQF57076.1\|571765_573001_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
LS483357.1\|SQF57062.1\|557675_559571_+\|CRISPR-associated-protein,-Csd1-family	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|273839

Protein	Function_ID	Function_description	E-value
LS483357.1\|SQF57059.1\|554815_556444_+\|ATP-dependent-RNA-helicase	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.08024e-98
LS483357.1\|SQF57066.1\|562132_562426_+\|hypothetical-cytosolic-protein	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
LS483357.1\|SQF57070.1\|565677_566418_+\|two-component-response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.6473e-83
LS483357.1\|SQF57063.1\|559575_560424_+\|putative-cytoplasmic-protein	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	6.49658e-159
LS483357.1\|SQF57069.1\|564483_565590_+\|bifunctional-methionine-sulfoxide-reductase-A/B	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	1.00806e-161
LS483357.1\|SQF57065.1\|561096_562122_+\|DNA-polymerase	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
LS483357.1\|SQF57067.1\|563094_563805_+\|cytochrome-c-type-biogenesis-protein	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	1.22933e-43
LS483357.1\|SQF57072.1\|568220_569300_+\|cytoplasmic-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	4.76739e-34
LS483357.1\|SQF57071.1\|566414_568148_+\|two-component-sensor-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	4.25578e-64
LS483357.1\|SQF57073.1\|569313_570030_+\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	2.72904e-105
LS483357.1\|SQF57061.1\|556947_557676_+\|CRISPR-associated-protein-cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.63992e-116
LS483357.1\|SQF57074.1\|570196_570670_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.23847e-66
LS483357.1\|SQF57075.1\|570811_571492_+\|Fumarate-and-nitrate-reduction-regulatory-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
LS483357.1\|SQF57068.1\|563817_564441_+\|disulfide-interchange-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.52991e-34
LS483357.1\|SQF57064.1\|560425_561100_+\|RecB-family-exonuclease	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	3.0744e-43
LS483357.1\|SQF57058.1\|552013_554662_+\|valyl-tRNA-synthetase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
LS483357.1\|SQF57057.1\|551448_552012_+\|shikimate-kinase	gnl\|CDD\|223637	COG0563, Adk, Adenylate kinase and related kinases [Nucleotide transport and metabolism].	0.00782951
LS483357.1\|SQF57076.1\|571765_573001_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
LS483357.1\|SQF57062.1\|557675_559571_+\|CRISPR-associated-protein,-Csd1-family	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0

>LS483357.1|SQF57066.1|562132_562426_+|hypothetical-cytosolic-protein
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>LS483357.1|SQF57065.1|561096_562122_+|DNA-polymerase
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>LS483357.1|SQF57064.1|560425_561100_+|RecB-family-exonuclease
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>LS483357.1|SQF57063.1|559575_560424_+|putative-cytoplasmic-protein
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLEGSINAYFAEKTGFSQEDAEAIKEVLVSLCENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>LS483357.1|SQF57062.1|557675_559571_+|CRISPR-associated-protein,-Csd1-family
MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIAPDYQHNQLKVIYFDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMIKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>LS483357.1|SQF57061.1|556947_557676_+|CRISPR-associated-protein-cas5
MYRSRDFYVRVSGQRALFTNPASKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>LS483357.1|SQF57060.1|556521_556815_+|ATP-dependent-RNA-helicase
MNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>LS483357.1|SQF57059.1|554815_556444_+|ATP-dependent-RNA-helicase
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANEEDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEERQIFSRTELRKFDDNDQKVHLTDVINLILGEENSVLAIFNTKKMVHNCYTMLKDMTDRPVYQLSTQSTTI
>LS483357.1|SQF57058.1|552013_554662_+|valyl-tRNA-synthetase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEDAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIVRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQAKYDATQERIAEMQKIKS
>LS483357.1|SQF57057.1|551448_552012_+|shikimate-kinase
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLTRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>LS483357.1|SQF57067.1|563094_563805_+|cytochrome-c-type-biogenesis-protein
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFDKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLVTIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHMLLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>LS483357.1|SQF57068.1|563817_564441_+|disulfide-interchange-protein
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDEMSTSKDKSMMADKTSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>LS483357.1|SQF57069.1|564483_565590_+|bifunctional-methionine-sulfoxide-reductase-A/B
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEEYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPLSPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHAFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>LS483357.1|SQF57070.1|565677_566418_+|two-component-response-regulator
MYSLLIVEDEYLIRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLDLSKKTETIQELVEQPQKEVSAIAMAIHEQLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>LS483357.1|SQF57071.1|566414_568148_+|two-component-sensor-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETISVLAKNSEIKDFASQIHQENDKQVFQLMKMVLATNSDLQAAVLVTKDGRTVSTNPQLIMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSSKKEWVVSVTQEVVDAVGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICSFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLVQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>LS483357.1|SQF57072.1|568220_569300_+|cytoplasmic-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEATPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKKNWISIILDDKITDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>LS483357.1|SQF57073.1|569313_570030_+|B3/4-domain-containing-protein
MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNSTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHAITSVHVLDKDNPHVPLFTEN
>LS483357.1|SQF57074.1|570196_570670_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>LS483357.1|SQF57075.1|570811_571492_+|Fumarate-and-nitrate-reduction-regulatory-protein
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>LS483357.1|SQF57076.1|571765_573001_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	LS483357.1	630720-630752	1	0.97

1. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to position: 630720-630752, mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448771	Streptococcus phage Javan481, complete genome	8314-8348	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK449010	Streptococcus phage Javan90, complete genome	10748-10782	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK449012	Streptococcus phage Javan94, complete genome	9759-9793	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448972	Streptococcus phage Javan520, complete genome	8239-8273	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448763	Streptococcus phage Javan451, complete genome	9432-9466	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448845	Streptococcus phage Javan118, complete genome	10042-10076	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448833	Streptococcus phage Javan87, complete genome	10748-10782	0	1.0
LS483357_1	1.4\|562805\|34\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448762	Streptococcus phage Javan447, complete genome	55-88	0	1.0
LS483357_1	1.4\|562805\|34\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448798	Streptococcus phage Javan533, complete genome	55-88	0	1.0
LS483357_1	1.4\|562805\|34\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448793	Streptococcus phage Javan523, complete genome	55-88	0	1.0
LS483357_1	1.4\|562805\|34\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448967	Streptococcus phage Javan510, complete genome	55-88	0	1.0
LS483357_1	1.4\|562805\|34\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448954	Streptococcus phage Javan476, complete genome	55-88	0	1.0
LS483357_1	1.4\|562805\|34\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	NC_004588	Streptococcus prophage 315.5, complete genome	204-237	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448771	Streptococcus phage Javan481, complete genome	6934-6966	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448681	Streptococcus phage Javan141, complete genome	6532-6564	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448944	Streptococcus phage Javan452, complete genome	11198-11230	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448672	Streptococcus phage Javan117, complete genome	6780-6812	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448849	Streptococcus phage Javan128, complete genome	6683-6715	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448774	Streptococcus phage Javan487, complete genome	6919-6951	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448958	Streptococcus phage Javan486, complete genome	9163-9195	0	1.0
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448742	Streptococcus phage Javan37, complete genome	9155-9187	0	1.0
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448862	Streptococcus phage Javan178, complete genome	8290-8324	1	0.971
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448681	Streptococcus phage Javan141, complete genome	8090-8124	1	0.971
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448672	Streptococcus phage Javan117, complete genome	8159-8193	1	0.971
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448849	Streptococcus phage Javan128, complete genome	8063-8097	1	0.971
LS483357_1	1.3\|562738\|35\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448850	Streptococcus phage Javan132, complete genome	12888-12922	1	0.971
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448767	Streptococcus phage Javan467, complete genome	6872-6904	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448973	Streptococcus phage Javan522, complete genome	8839-8871	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448862	Streptococcus phage Javan178, complete genome	6908-6940	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448942	Streptococcus phage Javan448, complete genome	6871-6903	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK449010	Streptococcus phage Javan90, complete genome	9367-9399	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK449012	Streptococcus phage Javan94, complete genome	8201-8233	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	6977-7009	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448969	Streptococcus phage Javan514, complete genome	9627-9659	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448943	Streptococcus phage Javan450, complete genome	6872-6904	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448972	Streptococcus phage Javan520, complete genome	6681-6713	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448786	Streptococcus phage Javan509, complete genome	6872-6904	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448778	Streptococcus phage Javan493, complete genome	8854-8886	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448963	Streptococcus phage Javan498, complete genome	3461-3493	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448773	Streptococcus phage Javan485, complete genome	9627-9659	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448851	Streptococcus phage Javan14, complete genome	12140-12172	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448833	Streptococcus phage Javan87, complete genome	9367-9399	1	0.97
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448673	Streptococcus phage Javan119, complete genome	9946-9978	1	0.97
LS483357_1	1.2\|562673\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562673-562705	33	MK448955	Streptococcus phage Javan478, complete genome	13965-13997	2	0.939
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448964	Streptococcus phage Javan502, complete genome	6851-6883	2	0.939
LS483357_1	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448845	Streptococcus phage Javan118, complete genome	8661-8693	5	0.848

1. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

2. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

3. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

4. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

5. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

6. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

7. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

8. spacer 1.4|562805|34|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

9. spacer 1.4|562805|34|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

10. spacer 1.4|562805|34|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

11. spacer 1.4|562805|34|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

12. spacer 1.4|562805|34|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

13. spacer 1.4|562805|34|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

14. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

15. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

16. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

17. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

18. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

19. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

20. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

21. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

22. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaatgccgattttaagc	Protospacer
**********************.************

23. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgatgccagttacaataccgattttaagc	Protospacer
**********.************************

24. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgatgccagttacaataccgattttaagc	Protospacer
**********.************************

25. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagtaacaataccgattttaagc	Protospacer
**************** ******************

26. spacer 1.3|562738|35|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgatgccagttacaataccgattttaagc	Protospacer
**********.************************

27. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

28. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

29. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

30. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

31. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

32. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

33. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

34. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

35. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

36. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

37. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

38. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

39. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

40. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

41. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

42. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

43. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

44. spacer 1.2|562673|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 2, identity: 0.939

atttcgtcacctcctcaatcaataatagagtca	CRISPR spacer
atttcgtcaactcctcaataaataatagagtca	Protospacer
********* ********* *************

45. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.939

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttaccctcaaagtaagagtg	Protospacer
***********.*****.***************

46. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 5, identity: 0.848

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ggaataagctgctttactctcaaagtaagagtg	Protospacer
   **.**** **********************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

621147 : 662798

Streptococcus_phage(67.92%)

head,integrase,tail,terminase

attL 623744:623763|attR 659340:659359

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57123.1\|621147_621987_+	degV family protein	A0A0N9SI50	Staphylococcus_phage	7.0e-13	35.7
SQF57124.1\|621961_622822_+	GDSL family lipase	NA	NA	NA	NA
SQF57125.1\|622799_623387_+	membrane protein	NA	NA	NA	NA
SQF57126.1\|623485_623761_+	DNA-binding protein HU 1	A7KV42	Bacillus_phage	2.6e-25	73.0
623744:623763	attL	NA	NA	NA	NA
SQF57127.1\|623849_624992_-\|integrase	phage integrase family protein	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
SQF57128.1\|625115_625634_-	HIRAN domain protein	E8ZDN5	Streptococcus_phage	1.6e-31	45.9
SQF57129.1\|625645_626401_-	Cro/CI family transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
SQF57130.1\|626602_626815_+	helix-turn-helix family protein	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
SQF57131.1\|626855_626987_+	Uncharacterised protein	NA	NA	NA	NA
SQF57132.1\|627084_627396_+	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
SQF57133.1\|627397_627583_+	phage protein	Q938N3	Temperate_phage	1.3e-20	83.6
SQF57134.1\|628086_628473_+	phage DNA replication protein	Q938N2	Temperate_phage	8.1e-25	51.9
SQF57135.1\|628453_628687_+	phage protein	Q938N1	Temperate_phage	2.8e-36	96.1
SQF57136.1\|628683_628824_+	phage protein	A0A1X9I6Y1	Streptococcus_phage	3.4e-05	54.5
SQF57137.1\|628832_629039_+	phage protein	NA	NA	NA	NA
SQF57138.1\|629094_629424_+	phage protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
SQF57139.1\|629426_630353_+	recombinase, phage RecT family protein	M1NRN6	Streptococcus_phage	1.2e-90	71.8
SQF57140.1\|630349_630550_+	phage protein	NA	NA	NA	NA
SQF57141.1\|630542_631340_+	phage protein	J7KGZ1	Streptococcus_phage	1.3e-130	83.8
SQF57142.1\|631461_631554_+	phage protein	A0A1S5SCN4	Streptococcus_phage	3.7e-05	70.0
SQF57143.1\|631704_632100_+	phage protein	A8ATL9	Listeria_phage	1.4e-19	52.3
SQF57144.1\|632096_633443_+	PcfJ	A8ATM0	Listeria_phage	1.0e-122	49.4
SQF57145.1\|633453_633786_+	phage protein	M1NS23	Streptococcus_phage	8.8e-36	67.0
SQF57146.1\|633782_634295_+	lactococcus phage M3 family protein	M1PFM2	Streptococcus_phage	1.7e-78	85.9
SQF57147.1\|634330_634648_+	phage protein	A1EAD7	Streptococcus_phage	9.0e-30	71.4
SQF57148.1\|634644_634800_+	phage protein	NA	NA	NA	NA
SQF57149.1\|634796_635048_+	phage protein	M1PF60	Streptococcus_phage	1.6e-18	59.0
SQF57150.1\|635123_635543_+	phage protein	A0A1X9I5B5	Streptococcus_phage	6.7e-57	79.9
SQF57151.1\|636142_636499_+	phage protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
SQF57152.1\|636495_637764_+	structural phage protein	M1PFL4	Streptococcus_phage	2.2e-188	75.6
SQF57153.1\|637756_639250_+	phage protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
SQF57154.1\|639255_639480_+	phage protein	NA	NA	NA	NA
SQF57155.1\|639531_639798_+	secreted phage protein	Q938K9	Temperate_phage	1.5e-38	100.0
SQF57156.1\|640117_641533_+\|terminase	phage terminase	A0A0B5A091	Streptococcus_phage	2.0e-214	74.6
SQF57157.1\|641612_642074_+	phage protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
SQF57158.1\|642098_643010_+\|head	phage, major head protein	M1PFL0	Streptococcus_phage	2.2e-113	67.0
SQF57159.1\|643009_643210_+	phage protein	NA	NA	NA	NA
SQF57160.1\|643219_643642_+	phage Gp19/Gp15/Gp42 family protein	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
SQF57161.1\|643601_643940_+	phage protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
SQF57162.1\|643932_644169_+	phage protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
SQF57163.1\|644169_644505_+	phage protein	A0A1P8BMR5	Lactococcus_phage	1.7e-34	64.9
SQF57164.1\|644516_645095_+\|tail	Major tail protein	A0A1X9I5X2	Streptococcus_phage	2.9e-58	62.9
SQF57165.1\|645105_645369_+	phage protein	A0A0B5A2F3	Streptococcus_phage	1.7e-18	54.7
SQF57166.1\|645383_645755_+	phage protein	M1PL84	Streptococcus_phage	1.2e-33	59.2
SQF57167.1\|645754_648112_+\|tail	minor tail protein GP26	M1NRG5	Streptococcus_phage	2.6e-134	50.3
SQF57168.1\|648108_648804_+	phage protein	A0A1B1P761	Bacillus_phage	4.7e-07	32.2
SQF57169.1\|648800_650762_+	phage endopeptidase	M1PKG3	Streptococcus_phage	2.4e-96	49.0
SQF57170.1\|650758_651874_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	4.8e-110	66.6
SQF57171.1\|651888_653172_+	gp58-like family protein	Q938J9	Temperate_phage	3.0e-15	34.7
SQF57172.1\|653168_653669_+	gp58-like family protein	A7J2A9	Streptococcus_phage	1.3e-59	85.8
SQF57173.1\|653677_654106_+	phage protein	Q938J8	Temperate_phage	3.7e-63	87.9
SQF57174.1\|654108_654741_+	phage protein	Q938J7	Temperate_phage	4.0e-45	50.5
SQF57175.1\|654752_655025_+	phage membrane protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
SQF57176.1\|655021_655249_+	phage protein	A7J2B3	Streptococcus_phage	2.0e-31	100.0
SQF57177.1\|655257_655374_+	phage membrane protein	A7J2B4	Streptococcus_phage	7.0e-09	97.1
SQF57178.1\|655367_656585_+	N-acetylmuramoyl-L-alanine amidase	A0A1P8VVM5	Streptococcus_phage	1.4e-163	60.1
SQF57179.1\|656720_657845_+	phage protein, Fic family	D7RWK9	Brochothrix_phage	3.1e-93	49.1
SQF57180.1\|658092_658875_+	Enterotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	4.3e-49	45.8
SQF57181.1\|658987_659170_+	paratox	A3F673	Streptococcus_phage	5.3e-19	75.0
SQF57182.1\|659700_661563_+	putative heavy metal-transporting ATPase	E4ZFI9	Streptococcus_phage	7.0e-90	33.8
659340:659359	attR	NA	NA	NA	NA
SQF57183.1\|661862_662798_-	dihydroorotate dehydrogenase 1A	A0A1V0SH91	Hokovirus	4.6e-66	45.1

DBSCAN-SWA_2

686088 : 715486

Streptococcus_phage(36.36%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57207.1\|686088_687117_-\|tRNA	S-adenosylmethionine-tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
SQF57208.1\|687318_688023_+	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
SQF57209.1\|688141_688858_+	16S pseudouridylate synthetase	NA	NA	NA	NA
SQF57210.1\|689152_690115_+	competence CoiA-like family protein	NA	NA	NA	NA
SQF57211.1\|690127_691933_+	oligoendopeptidase F	NA	NA	NA	NA
SQF57212.1\|692308_693505_+	major facilitator superfamily protein	NA	NA	NA	NA
SQF57213.1\|693606_694278_+	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	8.3e-09	27.6
SQF57214.1\|694340_695396_+	foldase protein prsA 1	NA	NA	NA	NA
SQF57215.1\|695782_698401_+\|tRNA	Alanyl-tRNA synthetase	A0A1V0SK38	Klosneuvirus	1.9e-61	33.9
SQF57216.1\|698754_698976_+	XRE family transcriptional regulator	NA	NA	NA	NA
SQF57217.1\|698972_699734_+	hypothetical membrane spanning protein	NA	NA	NA	NA
SQF57218.1\|699752_700448_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
SQF57219.1\|700544_700970_-	Transposase	A0A1P8CWQ3	Bacillus_phage	1.1e-27	44.9
SQF57220.1\|701015_701369_-	DNA-binding protein	A0A1B1P773	Bacillus_phage	1.2e-06	35.2
SQF57221.1\|701401_701695_-\|transposase	transposase	NA	NA	NA	NA
SQF57222.1\|701790_703017_-	chloride channel protein	NA	NA	NA	NA
SQF57223.1\|703164_703824_+\|transposase	truncated transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-115	91.7
SQF57224.1\|703801_704611_+\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	1.6e-131	92.5
SQF57225.1\|704636_705596_-	ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.8e-126	70.2
SQF57226.1\|706057_708217_-	ribonucleotide-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.2e-263	63.7
SQF57227.1\|708236_708455_-	glutaredoxin	A0A249XUR7	Enterococcus_phage	6.2e-14	49.3
SQF57228.1\|708847_709111_+	Phosphotransferase system, phosphocarrier protein HPr	NA	NA	NA	NA
SQF57229.1\|709115_710849_+	Phosphoenolpyruvate-protein phosphotransferase of PTS system	NA	NA	NA	NA
SQF57230.1\|711033_712461_+	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
SQF57231.1\|712554_713829_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
SQF57232.1\|713995_714655_+\|transposase	truncated transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-115	91.7
SQF57233.1\|714781_715486_+\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	2.7e-103	90.2

DBSCAN-SWA_3

1038280 : 1078715

Streptococcus_pyogenes_phage(48.28%)

integrase,portal,tail,terminase

attL 1038068:1038113|attR 1075943:1075988

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1038068:1038113	attL	NA	NA	NA	NA
SQF57542.1\|1038280_1038469_-	phage protein	A3F673	Streptococcus_phage	6.1e-18	73.3
SQF57543.1\|1038706_1039507_+	streptodornase	NA	NA	NA	NA
SQF57544.1\|1039778_1040213_+	phage membrane protein	NA	NA	NA	NA
SQF57545.1\|1040281_1040941_-	phage protein	A0A097PBF7	Streptococcus_pyogenes_phage	6.3e-118	96.3
SQF57546.1\|1040940_1041162_-	phage protein	A0A097PAX7	Streptococcus_pyogenes_phage	2.5e-18	84.5
SQF57547.1\|1041171_1041945_-	phage protein	A0A097PAV0	Streptococcus_pyogenes_phage	4.6e-128	94.6
SQF57548.1\|1041955_1042558_-	phage protein	A0A097PAX9	Streptococcus_pyogenes_phage	7.8e-91	98.8
SQF57549.1\|1042569_1043334_-	phage-associated cell wall hydrolase	A0A097PAT3	Streptococcus_pyogenes_phage	1.5e-150	100.0
SQF57550.1\|1043335_1043668_-	N-acetylmuramoyl-L-alanine amidase	A0A097PBF6	Streptococcus_pyogenes_phage	5.7e-51	100.0
SQF57551.1\|1043667_1043991_-	phage protein	A0A097PAX2	Streptococcus_pyogenes_phage	7.7e-53	100.0
SQF57552.1\|1044004_1044127_-	phage protein	A0A097PAU6	Streptococcus_pyogenes_phage	4.8e-16	100.0
SQF57553.1\|1044140_1044488_-	phage protein	A0A097PAX5	Streptococcus_pyogenes_phage	3.5e-59	100.0
SQF57554.1\|1044498_1046361_-	phage structural protein	A0A097PAT0	Streptococcus_pyogenes_phage	0.0e+00	99.8
SQF57555.1\|1046365_1049815_-	phage protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	99.0
SQF57556.1\|1049815_1051300_-\|tail	siphovirus tail component family protein	A0A097PAW9	Streptococcus_pyogenes_phage	1.8e-290	98.8
SQF57557.1\|1051300_1053106_-	phage, tape measure protein	A0A097PAU2	Streptococcus_pyogenes_phage	1.4e-249	94.8
SQF57558.1\|1053098_1053557_-	phage protein	A0A097PAX1	Streptococcus_pyogenes_phage	7.0e-76	93.4
SQF57559.1\|1053529_1053847_-	phage protein	A0A097PAS6	Streptococcus_pyogenes_phage	1.9e-51	98.1
SQF57560.1\|1053859_1054363_-	antigen A	A0A097PBF4	Streptococcus_pyogenes_phage	6.3e-78	98.7
SQF57561.1\|1054377_1054788_-	antigen B	A0A097PAW5	Streptococcus_pyogenes_phage	1.8e-70	99.3
SQF57562.1\|1054789_1055173_-	antigen C	A0A097PAT9	Streptococcus_pyogenes_phage	1.4e-56	93.0
SQF57563.1\|1055181_1055493_-	phage protein	A0A097PAW7	Streptococcus_pyogenes_phage	4.6e-47	94.2
SQF57564.1\|1055489_1055834_-	phage protein	A0A097PAS2	Streptococcus_pyogenes_phage	1.5e-54	99.1
SQF57565.1\|1055847_1056141_-	phage protein	A0A097PBF3	Streptococcus_pyogenes_phage	1.3e-46	99.0
SQF57566.1\|1056152_1057043_-	phage protein	A0A097PAW2	Streptococcus_pyogenes_phage	8.6e-86	99.4
SQF57567.1\|1057061_1057631_-	phage scaffold protein	A0A097PAW3	Streptococcus_pyogenes_phage	1.4e-60	90.5
SQF57568.1\|1057742_1057973_-	phage protein	Q938K9	Temperate_phage	4.0e-19	62.5
SQF57569.1\|1057979_1058888_-	phage protein	A0A097PBF2	Streptococcus_pyogenes_phage	2.4e-83	94.5
SQF57570.1\|1058856_1060182_-\|portal	portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	6.3e-234	95.6
SQF57571.1\|1060181_1061456_-\|terminase	terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	1.9e-251	99.8
SQF57572.1\|1061445_1061826_-	phage protein	A0A097PAR5	Streptococcus_pyogenes_phage	1.0e-64	100.0
SQF57573.1\|1062494_1062935_-	phage encoded transcriptional regulator, ArpU family	Q938L8	Temperate_phage	5.0e-79	100.0
SQF57574.1\|1063208_1063379_-	phage protein	A0A097PAS8	Streptococcus_pyogenes_phage	1.1e-26	98.2
SQF57575.1\|1063375_1063882_-	phage protein	Q938L9	Temperate_phage	9.8e-95	100.0
SQF57576.1\|1063878_1064049_-	phage protein	Q938M0	Temperate_phage	4.2e-26	100.0
SQF57577.1\|1064045_1064450_-	phage protein	Q938M1	Temperate_phage	6.0e-71	100.0
SQF57578.1\|1064459_1064729_-	phage protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
SQF57579.1\|1064725_1065010_-	phage protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
SQF57580.1\|1065003_1065255_-	phage protein	A0A1P8VVV4	Streptococcus_phage	4.3e-43	100.0
SQF57581.1\|1065251_1065608_-	phage protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
SQF57582.1\|1065591_1065912_-	phage protein	A0A1P8VVL5	Streptococcus_phage	2.0e-53	100.0
SQF57583.1\|1066156_1067077_-	DNA primase	A0A1P8VVM0	Streptococcus_phage	5.2e-179	99.7
SQF57584.1\|1067082_1067637_-	DNA primase	J7KH16	Streptococcus_phage	1.4e-86	93.9
SQF57585.1\|1067626_1068439_-	phage protein	A0A1P8VVM6	Streptococcus_phage	7.2e-156	99.3
SQF57586.1\|1068441_1068900_-	phage protein	A0A1P8VVN0	Streptococcus_phage	3.8e-82	100.0
SQF57587.1\|1068915_1070145_-	phage DNA/RNA helicase	A0A1P8VVM2	Streptococcus_phage	3.3e-237	100.0
SQF57588.1\|1070246_1070927_-	phage protein	A0A1P8VVS4	Streptococcus_phage	1.6e-129	100.0
SQF57589.1\|1070927_1071410_-	phage protein	A0A1P8VVS5	Streptococcus_phage	1.2e-78	100.0
SQF57590.1\|1071636_1071951_-	Transcriptional regulator, Cro/CI family	A0A1P8VVN6	Streptococcus_phage	1.7e-52	100.0
SQF57591.1\|1071966_1072101_-	phage protein	A0A1P8VVR9	Streptococcus_phage	6.7e-19	100.0
SQF57592.1\|1072131_1072383_-	phage protein	A0A1P8VVV6	Streptococcus_phage	2.8e-42	100.0
SQF57593.1\|1072477_1072696_-	Transcriptional regulator, Cro family	A0A1P8VVR5	Streptococcus_phage	4.1e-34	100.0
SQF57594.1\|1072884_1073244_+	Transcriptional regulator, MerR family	A0A1P8VVN3	Streptococcus_phage	1.8e-58	98.3
SQF57595.1\|1073227_1073605_+	cI-like repressor	A0A1P8VVK5	Streptococcus_phage	4.0e-69	100.0
SQF57596.1\|1073615_1073768_+	phage protein	A0A1P8VVQ0	Streptococcus_phage	1.5e-19	98.0
SQF57597.1\|1073938_1074625_+	phage protein	A0A1P8VVT3	Streptococcus_phage	5.7e-122	100.0
SQF57598.1\|1074746_1075886_+\|integrase	phage integrase	A1EAB7	Streptococcus_phage	4.4e-119	55.8
SQF57599.1\|1075968_1077009_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.1e-68	43.9
1075943:1075988	attR	NA	NA	NA	NA
SQF57600.1\|1077252_1077846_-	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
SQF57601.1\|1077845_1078715_-	glucose-1-phosphate thymidyl transferase	K7QKA7	Escherichia_phage	2.4e-101	64.6

DBSCAN-SWA_4

1089394 : 1143406

Bacillus_virus(20.0%)

head,transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57613.1\|1089394_1090294_-\|tRNA	tRNA delta(2)-isopentenylpyrophosphate transferase	NA	NA	NA	NA
SQF57614.1\|1090427_1090604_+	putative uncharacterized protein ORF 3	NA	NA	NA	NA
SQF57615.1\|1090721_1091630_-	exfoliative toxin	NA	NA	NA	NA
SQF57616.1\|1091866_1092286_-	glutathione S-transferase	NA	NA	NA	NA
SQF57617.1\|1092596_1093583_-	Rhodanese domain protein UPF0176, Firmicutes subgroup	NA	NA	NA	NA
SQF57618.1\|1093784_1094087_+	Uncharacterised protein	NA	NA	NA	NA
SQF57619.1\|1094634_1095840_-	30S ribosomal protein S1	NA	NA	NA	NA
SQF57620.1\|1096228_1096459_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
SQF57621.1\|1096492_1097320_-\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	9.6e-132	92.5
SQF57622.1\|1097297_1097957_-\|transposase	truncated transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-115	91.7
SQF57623.1\|1098077_1099100_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
SQF57624.1\|1099222_1101646_-	topoisomerase IV subunit	G3M9Z5	Bacillus_virus	1.6e-97	33.3
SQF57625.1\|1101772_1103722_-	topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	7.3e-122	42.0
SQF57626.1\|1103856_1104498_+	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
SQF57627.1\|1104555_1105824_-	dihydroorotase	NA	NA	NA	NA
SQF57628.1\|1105955_1106609_-	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	1.5e-39	39.7
SQF57629.1\|1106741_1107392_-	amino-acid ABC transporter permease yckA	NA	NA	NA	NA
SQF57630.1\|1107420_1108284_-	cystine-binding protein	NA	NA	NA	NA
SQF57631.1\|1108401_1109856_-	amidase	NA	NA	NA	NA
SQF57632.1\|1110052_1110682_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
SQF57633.1\|1110739_1111432_-	orotidine 5'-phosphate decarboxylase	NA	NA	NA	NA
SQF57634.1\|1111708_1112245_-	Uncharacterised protein	NA	NA	NA	NA
SQF57635.1\|1112466_1113372_+	LysR family transcriptional regulator	NA	NA	NA	NA
SQF57636.1\|1113451_1114240_-	LytR family transcriptional regulator	NA	NA	NA	NA
SQF57637.1\|1114232_1114946_-	Purine nucleoside phosphorylase	NA	NA	NA	NA
SQF57638.1\|1115608_1116418_-	purine nucleoside phosphorylase	Q5YBA4	Grouper_iridovirus	5.1e-53	42.2
SQF57639.1\|1116401_1116842_-	arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	4.4e-35	54.5
SQF57640.1\|1116860_1118072_-	phosphopentomutase	NA	NA	NA	NA
SQF57641.1\|1118148_1118832_-	ribose-5-phosphate isomerase A	NA	NA	NA	NA
SQF57642.1\|1119209_1121309_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	5.1e-121	39.2
SQF57643.1\|1121366_1122110_-	virulence factor relevant regulator	NA	NA	NA	NA
SQF57644.1\|1122257_1122857_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
SQF57645.1\|1122866_1124096_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	7.8e-138	60.5
SQF57646.1\|1124225_1124396_-	hypothetical membrane associated protein	NA	NA	NA	NA
SQF57647.1\|1124415_1124913_-	dihydrofolate reductase	W5QU76	Bacillus_phage	8.6e-11	34.4
SQF57648.1\|1124992_1125856_-	thymidylate synthase	U5J9N5	Bacillus_phage	1.7e-83	53.2
SQF57649.1\|1126040_1127216_+	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
SQF57650.1\|1127202_1128480_+	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
SQF57651.1\|1128709_1129699_-	isopentenyl pyrophosphate isomerase	NA	NA	NA	NA
SQF57652.1\|1129691_1130699_-	phosphomevalonate kinase	NA	NA	NA	NA
SQF57653.1\|1130691_1131636_-	diphosphomevalonate decarboxylase	NA	NA	NA	NA
SQF57654.1\|1131617_1132496_-	mevalonate kinase	NA	NA	NA	NA
SQF57655.1\|1132789_1134022_-	two component system histidine kinase	NA	NA	NA	NA
SQF57656.1\|1134030_1134699_-	two-component response regulator	W8CYM9	Bacillus_phage	2.3e-19	28.8
SQF57657.1\|1134701_1135352_-	GTP pyrophosphokinase	NA	NA	NA	NA
SQF57658.1\|1135603_1137589_+	5'-nucleotidase	NA	NA	NA	NA
SQF57659.1\|1137670_1138081_-	polypeptide deformylase family protein	E3SLL2	Synechococcus_phage	6.9e-06	30.6
SQF57660.1\|1138970_1140848_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.1e-63	31.5
SQF57661.1\|1140844_1142053_-\|head	poly A polymerase head domain-containing protein	H7BUW3	unidentified_phage	5.3e-38	45.0
SQF57662.1\|1142177_1143026_-	degV family protein	NA	NA	NA	NA
SQF57663.1\|1143025_1143406_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1185115 : 1195719

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57705.1\|1185115_1186258_-	aminotransferase class-V family protein	A0A1X6WFP1	Pacmanvirus	1.1e-24	27.3
SQF57706.1\|1186492_1186933_+	membrane protein	NA	NA	NA	NA
SQF57707.1\|1186962_1188231_+	folylpolyglutamate synthase	NA	NA	NA	NA
SQF57708.1\|1188318_1189671_-	glutathione reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.7
SQF57709.1\|1189892_1190234_-	hypothetical cytosolic protein	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
SQF57710.1\|1190294_1191461_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
SQF57711.1\|1191554_1192241_-	3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
SQF57712.1\|1192237_1193401_-	SAM-dependent methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
SQF57713.1\|1193508_1195719_+	phosphoglycerol transferase	W6LM83	Streptococcus_phage	2.9e-268	69.1

DBSCAN-SWA_6

1218681 : 1261718

Bacillus_virus(14.29%)

transposase,bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57736.1\|1218681_1219296_-\|transposase	transposase	NA	NA	NA	NA
SQF57737.1\|1219307_1219814_-\|transposase	transposase	NA	NA	NA	NA
SQF57738.1\|1219985_1220348_+	large-conductance mechanosensitive channel	NA	NA	NA	NA
SQF57739.1\|1220475_1220682_-	30S ribosomal protein S21	NA	NA	NA	NA
SQF57740.1\|1220792_1221605_-	Arginine-binding protein	NA	NA	NA	NA
SQF57741.1\|1221744_1225377_-	recombination helicase AddA	G3MA40	Bacillus_virus	1.6e-21	25.3
SQF57742.1\|1225373_1228589_-	ATP-dependent nuclease subunit B	NA	NA	NA	NA
SQF57743.1\|1228739_1229657_+	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	1.3e-33	37.0
SQF57744.1\|1229758_1230427_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-30	36.2
SQF57745.1\|1230436_1231513_-	permease family protein	NA	NA	NA	NA
SQF57746.1\|1231585_1231972_-	Probable type II DNA modification enzyme	NA	NA	NA	NA
SQF57747.1\|1231964_1232342_-	salt-stress induced protein	NA	NA	NA	NA
SQF57748.1\|1232451_1234857_-\|tRNA	phenylalanyl-tRNA synthetase subunit beta	NA	NA	NA	NA
SQF57749.1\|1235066_1236110_-\|tRNA	phenylalanyl-tRNA synthetase alpha subunit	A0A2K9L3A8	Tupanvirus	4.6e-30	34.3
SQF57750.1\|1236392_1236692_-	DNA-entry nuclease	NA	NA	NA	NA
SQF57751.1\|1236678_1237257_-	DNA-entry nuclease	NA	NA	NA	NA
SQF57752.1\|1237292_1237481_-	epuA protein	NA	NA	NA	NA
SQF57753.1\|1237484_1238756_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
SQF57754.1\|1238820_1239078_-	membrane protein	NA	NA	NA	NA
SQF57755.1\|1239343_1239760_-	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
SQF57756.1\|1239772_1241179_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
SQF57757.1\|1241340_1242216_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
SQF57758.1\|1242231_1243740_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
SQF57759.1\|1243755_1244292_-	ATP synthase delta chain	NA	NA	NA	NA
SQF57760.1\|1244291_1244786_-	F0F1 ATP synthase subunit B	NA	NA	NA	NA
SQF57761.1\|1244803_1245520_-	F0F1 ATP synthase subunit A	NA	NA	NA	NA
SQF57762.1\|1245554_1245752_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
SQF57763.1\|1246159_1247182_-	lipid kinase	A0A1V0SBJ0	Catovirus	6.1e-19	27.9
SQF57764.1\|1247195_1249154_-	NAD-dependent DNA ligase	A0A0K2QQN8	Ralstonia_phage	5.8e-103	34.9
SQF57765.1\|1250124_1252857_-	LPXTG-motif cell wall anchor domain-containing protein	NA	NA	NA	NA
SQF57766.1\|1253428_1254547_-	ABC transporter	NA	NA	NA	NA
SQF57767.1\|1254543_1255671_-	ABC transporter	NA	NA	NA	NA
SQF57768.1\|1255679_1256603_-	ABC transporter family protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-33	38.1
SQF57769.1\|1256625_1257309_-	streptolysin S biosynthesis protein SagF	NA	NA	NA	NA
SQF57770.1\|1257305_1257977_-\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
SQF57771.1\|1257951_1259310_-\|bacteriocin	bacteriocin biosynthesis docking scaffold, SagD family domain-containing protein	NA	NA	NA	NA
SQF57772.1\|1259329_1260388_-\|bacteriocin	bacteriocin biosynthesis cyclodehydratase	NA	NA	NA	NA
SQF57773.1\|1260384_1261335_-	sagB-type dehydrogenase domain-containing protein	NA	NA	NA	NA
SQF57774.1\|1261556_1261718_-\|bacteriocin	bacteriocin protoxin, streptolysin S family protein	NA	NA	NA	NA

DBSCAN-SWA_7

1269622 : 1338174

Streptococcus_phage(60.29%)

portal,terminase,integrase,tail,holin,transposase,tRNA,capsid,protease

attL 1289671:1289691|attR 1333467:1333487

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57777.1\|1269622_1270144_+\|transposase	transposase	A0A1X9I619	Streptococcus_phage	1.8e-72	82.1
SQF57778.1\|1270732_1272040_-	Enolase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
SQF57779.1\|1272266_1272725_+	hypothetical cytosolic protein	W6LLD2	Streptococcus_phage	1.8e-18	39.1
SQF57780.1\|1272856_1274581_-	septation ring formation regulator	NA	NA	NA	NA
SQF57781.1\|1274948_1276901_-	DNA gyrase subunit B	G3M9Z3	Bacillus_virus	6.8e-144	46.3
SQF57782.1\|1276901_1277471_-	hydrolase, haloacid dehalogenase-like family	NA	NA	NA	NA
SQF57783.1\|1278498_1278846_-	50S ribosomal protein L19	NA	NA	NA	NA
SQF57784.1\|1278960_1280223_-	chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	1.9e-94	50.8
SQF57785.1\|1280215_1280500_-	chorismate mutase	NA	NA	NA	NA
SQF57786.1\|1280675_1281125_-	flavodoxin	NA	NA	NA	NA
SQF57787.1\|1281518_1282460_+	DHH family protein	NA	NA	NA	NA
SQF57788.1\|1282574_1282835_+	50S ribosomal protein L31	NA	NA	NA	NA
SQF57789.1\|1282932_1284132_-	tagatose-6-phosphate ketose/aldose isomerase	NA	NA	NA	NA
SQF57790.1\|1284151_1284874_-	GntR family transcriptional regulator	NA	NA	NA	NA
SQF57791.1\|1285116_1286580_+	Phage-associated cell wall hydrolase	A0A1X9I5T2	Streptococcus_phage	2.2e-256	92.1
SQF57792.1\|1286596_1288144_-	high-affinity zinc uptake system protein	NA	NA	NA	NA
SQF57793.1\|1288295_1289714_-	dipeptidase	NA	NA	NA	NA
1289671:1289691	attL	NA	NA	NA	NA
SQF57794.1\|1290025_1290784_+	DNA/RNA non-specific endonuclease family protein	NA	NA	NA	NA
SQF57795.1\|1290894_1291602_+	exotoxin type C	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
SQF57796.1\|1291669_1292875_-	phage-associated cell wall hydrolase	Q938J4	Temperate_phage	1.6e-204	83.3
SQF57797.1\|1292990_1293218_-	phage protein	A7J2B3	Streptococcus_phage	5.8e-31	98.7
SQF57798.1\|1293214_1293490_-\|holin	phage holin	A7J2B2	Streptococcus_phage	2.6e-41	100.0
SQF57799.1\|1293499_1294117_-	phage protein	Q938J7	Temperate_phage	5.0e-77	89.3
SQF57800.1\|1294119_1294551_-	phage protein	Q938J8	Temperate_phage	1.3e-63	89.5
SQF57801.1\|1294562_1296449_-	gp58-like family protein	Q938J9	Temperate_phage	3.1e-218	84.7
SQF57802.1\|1296461_1297472_-	phage hyaluronidase	Q938K0	Temperate_phage	7.8e-136	75.8
SQF57803.1\|1297468_1299613_-	Phage endopeptidase	Q938K1	Temperate_phage	0.0e+00	94.7
SQF57804.1\|1299609_1300317_-	phage protein	Q938K2	Temperate_phage	6.8e-94	71.9
SQF57805.1\|1300316_1304240_-\|tail	phage tail protein	J7KDT4	Streptococcus_phage	1.9e-238	48.5
SQF57806.1\|1304449_1304776_-	phage protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
SQF57807.1\|1304828_1305437_-\|tail	major tail protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
SQF57808.1\|1305452_1305878_-	phage protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
SQF57809.1\|1305874_1306252_-	phage protein	J7KDM3	Streptococcus_phage	1.8e-45	72.8
SQF57810.1\|1306248_1306596_-	phage protein	J7KJ42	Streptococcus_phage	2.9e-50	88.2
SQF57811.1\|1306592_1306895_-	phage protein	J7KC36	Streptococcus_phage	1.3e-41	88.8
SQF57812.1\|1307039_1308227_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
SQF57813.1\|1308251_1308917_-\|protease	phage ClpP protease	M1Q115	Streptococcus_phage	3.5e-92	78.1
SQF57814.1\|1308894_1310115_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
SQF57815.1\|1310148_1310373_-	phage protein	Q938K9	Temperate_phage	3.6e-17	61.4
SQF57816.1\|1310365_1310536_-	phage protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
SQF57817.1\|1310532_1312281_-\|terminase	phage terminase, large subunit	J7KKD1	Streptococcus_phage	0.0e+00	96.2
SQF57818.1\|1312290_1312521_-	Uncharacterised protein	NA	NA	NA	NA
SQF57819.1\|1312523_1312991_-\|terminase	phage terminase, small subunit	J7KC46	Streptococcus_phage	3.9e-82	98.7
SQF57820.1\|1313161_1313500_-	Phage endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
SQF57821.1\|1313496_1313637_-	Uncharacterised protein	NA	NA	NA	NA
SQF57822.1\|1313735_1313921_+	phage protein	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
SQF57823.1\|1313972_1314350_+	phage protein	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
SQF57824.1\|1314476_1315406_-	phage protein	A0A126HAU2	Lactococcus_phage	4.9e-100	71.8
SQF57825.1\|1315988_1316426_-	phage protein	A0A097PBF1	Streptococcus_pyogenes_phage	6.7e-76	97.9
SQF57826.1\|1316701_1316872_-	phage protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
SQF57827.1\|1316868_1317594_-	phage protein	Q938L9	Temperate_phage	3.1e-25	44.8
SQF57828.1\|1317641_1318406_-	Adenine-specific methyltransferase	A0A1S5SE41	Streptococcus_phage	4.2e-134	92.3
SQF57829.1\|1318395_1318878_-	DNA N-4 cytosine methyltransferase M.NgoMXV	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
SQF57830.1\|1318881_1319166_-	phage protein	A3F628	Streptococcus_phage	4.6e-33	79.8
SQF57831.1\|1319162_1319576_-	phage protein	Q938M1	Temperate_phage	6.4e-36	65.2
SQF57832.1\|1319585_1319855_-	phage protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
SQF57833.1\|1319851_1320037_-	phage protein	A3F626	Streptococcus_phage	1.7e-12	94.7
SQF57834.1\|1320029_1320311_-	phage protein	J7KDH9	Streptococcus_phage	2.5e-31	75.0
SQF57835.1\|1320307_1320439_-	phage protein	Q938M4	Temperate_phage	3.0e-08	44.4
SQF57836.1\|1320435_1320792_-	phage protein	A0A1P8VVP9	Streptococcus_phage	7.7e-54	87.3
SQF57837.1\|1320775_1321096_-	phage protein	A0A1P8VVL5	Streptococcus_phage	1.9e-51	95.3
SQF57838.1\|1321092_1321506_-	phage protein	A0A2H4JHE6	uncultured_Caudovirales_phage	1.6e-15	51.1
SQF57839.1\|1321767_1323243_-	DNA primase	A0A1P8VVM0	Streptococcus_phage	2.4e-242	84.2
SQF57840.1\|1323232_1324045_-	phage protein	J7KH42	Streptococcus_phage	1.9e-153	97.4
SQF57841.1\|1324047_1324506_-	phage protein	A0A1P8VVN0	Streptococcus_phage	2.2e-77	94.1
SQF57842.1\|1324521_1325751_-	phage DNA/RNA helicase	J7KK96	Streptococcus_phage	3.3e-229	95.4
SQF57843.1\|1325770_1325866_-	Helicase	NA	NA	NA	NA
SQF57844.1\|1325852_1326545_-	phage protein	J7KC09	Streptococcus_phage	5.9e-127	96.1
SQF57845.1\|1326531_1326822_-	phage protein	A0A1S5PRW6	Streptococcus_phage	2.9e-19	44.6
SQF57846.1\|1326952_1327135_-	Uncharacterised protein	A0A2P0ZLA4	Lactobacillus_phage	4.0e-06	43.8
SQF57847.1\|1327122_1327335_-	phage protein	NA	NA	NA	NA
SQF57848.1\|1327344_1327485_-	phage protein	A0A1P8VVR9	Streptococcus_phage	4.2e-16	91.1
SQF57849.1\|1327481_1327727_-	Uncharacterised protein	NA	NA	NA	NA
SQF57850.1\|1327799_1327985_-	phage protein	J7KH19	Streptococcus_phage	3.5e-18	68.9
SQF57851.1\|1328129_1328360_+	Uncharacterised protein	NA	NA	NA	NA
SQF57852.1\|1328319_1328466_-	Uncharacterised protein	NA	NA	NA	NA
SQF57853.1\|1328522_1328732_+	phage protein	NA	NA	NA	NA
SQF57854.1\|1328690_1328936_-	phage protein	A0A097PAP6	Streptococcus_pyogenes_phage	1.6e-34	93.8
SQF57855.1\|1328977_1329184_-	phage protein	A0A1X9I5S3	Streptococcus_phage	1.1e-17	64.7
SQF57856.1\|1329276_1329918_+	phage protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
SQF57857.1\|1330016_1330175_-	phage membrane protein	J7KH24	Streptococcus_phage	7.1e-20	88.5
SQF57858.1\|1330561_1331311_+	phage transcriptional repressor	A0A097PBE5	Streptococcus_pyogenes_phage	4.5e-80	63.8
SQF57859.1\|1331336_1331879_+	phage protein	Q4ZA70	Staphylococcus_virus	3.9e-33	41.9
SQF57860.1\|1332029_1333445_+\|integrase	integrase	A5GZ62	Lactococcus_phage	1.4e-109	47.2
SQF57861.1\|1333641_1334553_-	sporulation Regulator WhiA C terminal domain-containing protein	Q7AWZ3	Streptococcus_phage	2.9e-105	64.4
1333467:1333487	attR	NA	NA	NA	NA
SQF57862.1\|1334549_1335527_-	transporter	A1IMD5	Streptococcus_phage	1.2e-138	74.2
SQF57863.1\|1335523_1336414_-	P-loop ATPase protein family protein	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
SQF57864.1\|1336827_1338174_-\|tRNA	asparaginyl-tRNA synthetase	A0A2P1EMB4	Moumouvirus	1.4e-55	30.8

DBSCAN-SWA_8

1447931 : 1477196

Tupanvirus(14.29%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF57975.1\|1447931_1449875_-\|tRNA	threonyl-tRNA synthetase	A0A2K9L297	Tupanvirus	8.0e-121	38.7
SQF57976.1\|1450296_1451631_-	glycosyl transferases group 1 family protein	NA	NA	NA	NA
SQF57977.1\|1451632_1452631_-	glycosyltransferase	NA	NA	NA	NA
SQF57978.1\|1452761_1453763_-	Catabolite control protein A	C6ZCU4	Enterobacteria_phage	6.1e-24	28.5
SQF57979.1\|1453936_1455022_+	Xaa-Pro dipeptidase	NA	NA	NA	NA
SQF57980.1\|1455070_1455736_+	NAD(P)H nitroreductase yfkO	NA	NA	NA	NA
SQF57981.1\|1455746_1456124_+	bleomycin resistance protein	NA	NA	NA	NA
SQF57982.1\|1456268_1457195_+	glucosyl transferase family 2	V5USA4	Oenococcus_phage	1.5e-77	47.5
SQF57983.1\|1457405_1458089_+	membrane protein	NA	NA	NA	NA
SQF57984.1\|1458088_1459015_+	membrane protein	NA	NA	NA	NA
SQF57985.1\|1459064_1459712_+	pyroglutamyl-peptidase I	NA	NA	NA	NA
SQF57986.1\|1459826_1460537_-	glutamine cyclotransferase	NA	NA	NA	NA
SQF57987.1\|1460551_1461019_-	ssrA-binding protein	W5RAM5	Staphylococcus_phage	7.5e-41	57.0
SQF57988.1\|1461021_1463355_-	ribonuclease R	Q0GXV6	Lactococcus_phage	3.0e-90	39.6
SQF57989.1\|1463448_1463685_-	preprotein translocase subunit	NA	NA	NA	NA
SQF57990.1\|1463873_1465067_-	major facilitator superfamily protein	NA	NA	NA	NA
SQF57991.1\|1465188_1466691_-	ATPase	A0A248XCZ8	Klebsiella_phage	3.9e-75	41.6
SQF57992.1\|1466880_1467474_-	dephospho-CoA kinase	NA	NA	NA	NA
SQF57993.1\|1467470_1468298_-	formamidopyrimidine-DNA glycosylase	A0A127AWE5	Bacillus_phage	3.9e-16	27.5
SQF57994.1\|1468469_1469336_-	transcriptional regulator	NA	NA	NA	NA
SQF57995.1\|1470406_1470676_+	Uncharacterised protein	NA	NA	NA	NA
SQF57996.1\|1471023_1471413_-	histidine kinase	NA	NA	NA	NA
SQF57997.1\|1471514_1472582_-	Uncharacterised protein	NA	NA	NA	NA
SQF57998.1\|1472826_1473237_-	Uncharacterised protein	NA	NA	NA	NA
SQF57999.1\|1473430_1473712_-	Uncharacterised protein	NA	NA	NA	NA
SQF58000.1\|1474250_1474448_-	hypothetical membrane associated protein	NA	NA	NA	NA
SQF58001.1\|1474460_1474688_-	BlpM	NA	NA	NA	NA
SQF58002.1\|1475002_1475425_+\|transposase	transposase	NA	NA	NA	NA
SQF58003.1\|1475421_1475571_+\|transposase	IS1191 transposase	NA	NA	NA	NA
SQF58004.1\|1475879_1476062_-\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQF58005.1\|1476076_1476322_-\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQF58006.1\|1476627_1476777_-\|transposase	IS1191 transposase	NA	NA	NA	NA
SQF58007.1\|1476773_1477196_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_9

1480560 : 1531194

Bacillus_phage(20.0%)

transposase,bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF58010.1\|1480560_1481178_+\|bacteriocin	bacteriocin export accessory protein	NA	NA	NA	NA
SQF58011.1\|1481254_1481380_+	COMC family	NA	NA	NA	NA
SQF58012.1\|1481527_1482862_-	two-component system, AgrA family, sensor histidine kinase AgrC	NA	NA	NA	NA
SQF58013.1\|1482862_1483612_-	response regulator	A0A1V0E029	Clostridioides_phage	9.6e-22	28.0
SQF58014.1\|1484100_1484415_-\|transposase	transposase	A0A1P8CWQ3	Bacillus_phage	7.1e-19	48.0
SQF58015.1\|1484517_1484814_-\|transposase	transposase	A0A1B1P773	Bacillus_phage	6.5e-06	42.0
SQF58016.1\|1485193_1485511_-	role in replication	NA	NA	NA	NA
SQF58017.1\|1485559_1485790_-\|bacteriocin	bacteriocin class II with double-glycine leader peptide	NA	NA	NA	NA
SQF58018.1\|1486689_1486917_-	Uncharacterised protein	NA	NA	NA	NA
SQF58019.1\|1487002_1487179_-	Uncharacterised protein	NA	NA	NA	NA
SQF58020.1\|1487156_1487381_-	blpU	NA	NA	NA	NA
SQF58021.1\|1487678_1487915_+\|bacteriocin	bacteriocin processing peptidase	NA	NA	NA	NA
SQF58022.1\|1488019_1488730_+\|bacteriocin	bacteriocin processing peptidase	NA	NA	NA	NA
SQF58023.1\|1489225_1489456_-	truncated SilB	NA	NA	NA	NA
SQF58024.1\|1490000_1490255_+	Uncharacterised protein	NA	NA	NA	NA
SQF58025.1\|1490559_1491036_-	phosphohydrolase	NA	NA	NA	NA
SQF58026.1\|1491055_1491952_-	GTP-binding protein Era	NA	NA	NA	NA
SQF58027.1\|1492071_1492479_-	diacylglycerol kinase	NA	NA	NA	NA
SQF58028.1\|1492459_1492957_-\|protease	metalloprotease	NA	NA	NA	NA
SQF58029.1\|1493115_1493691_-	uracil DNA glycosylase superfamily protein	NA	NA	NA	NA
SQF58030.1\|1493736_1494789_-	phosphate starvation-induced protein	W8D063	Erwinia_phage	1.2e-46	50.0
SQF58031.1\|1494947_1496720_-	myosin-cross-reactive antigen	NA	NA	NA	NA
SQF58032.1\|1497035_1498217_-	lysM domain protein	A0A0E3XB61	Gordonia_phage	5.6e-16	40.5
SQF58033.1\|1498372_1498588_-	hypothetical cytosolic protein	NA	NA	NA	NA
SQF58034.1\|1498584_1499094_-	methionine sulfoxide reductase A	NA	NA	NA	NA
SQF58035.1\|1499166_1500024_-	s1 RNA binding domain	NA	NA	NA	NA
SQF58036.1\|1500132_1500690_-	ribosome recycling factor	NA	NA	NA	NA
SQF58037.1\|1500718_1501447_-	uridylate kinase	NA	NA	NA	NA
SQF58038.1\|1501768_1502458_-	50S ribosomal protein L1	NA	NA	NA	NA
SQF58039.1\|1502563_1502989_-	50S ribosomal protein L11	NA	NA	NA	NA
SQF58040.1\|1503232_1503586_+	integral membrane protein	NA	NA	NA	NA
SQF58041.1\|1503655_1506061_-	cell division protein FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
SQF58042.1\|1506277_1507084_+	cyclophilin type peptidyl-prolyl cis-trans isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
SQF58043.1\|1507231_1508086_-	ABC 3 transport family protein	NA	NA	NA	NA
SQF58044.1\|1508086_1508812_-	manganese transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.1e-17	32.6
SQF58045.1\|1508875_1509808_-	manganese-binding protein	NA	NA	NA	NA
SQF58046.1\|1509953_1510601_+	metalloregulator ScaR	NA	NA	NA	NA
SQF58047.1\|1510697_1511039_-	Uncharacterised protein	NA	NA	NA	NA
SQF58048.1\|1511189_1511885_-	MTA/SAH nucleosidase	NA	NA	NA	NA
SQF58049.1\|1511904_1512156_-	membrane protein	NA	NA	NA	NA
SQF58050.1\|1512155_1512710_-	ADP-ribose pyrophosphatase	NA	NA	NA	NA
SQF58051.1\|1512740_1514123_-	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L4K9	Tupanvirus	1.3e-32	36.4
SQF58052.1\|1514295_1515633_-	phosphoglycerate transporter protein	NA	NA	NA	NA
SQF58053.1\|1515965_1516925_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
SQF58054.1\|1517000_1517699_-	3-ketoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	2.3e-09	24.4
SQF58055.1\|1517691_1517928_-	Protein of uncharacterised function (DUF2829)	NA	NA	NA	NA
SQF58056.1\|1518627_1519098_+	Protein of uncharacterised function (DUF3644)	A0A0N9RUA4	Staphylococcus_phage	7.8e-54	65.8
SQF58057.1\|1519918_1520032_-	Uncharacterised protein	NA	NA	NA	NA
SQF58058.1\|1520108_1520816_+	phage protein	NA	NA	NA	NA
SQF58059.1\|1520909_1521161_-	hypothetical membrane spanning protein	NA	NA	NA	NA
SQF58060.1\|1521393_1521831_-	hypothetical membrane associated protein	NA	NA	NA	NA
SQF58061.1\|1522068_1522581_-	hypothetical membrane associated protein	NA	NA	NA	NA
SQF58062.1\|1523021_1523774_+	ADP-ribosyltransferase	NA	NA	NA	NA
SQF58063.1\|1523979_1526160_-	ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.6e-170	43.1
SQF58064.1\|1526179_1526614_-	nrdI protein	R4JF54	Bacillus_phage	1.2e-11	37.5
SQF58065.1\|1526617_1527631_-	ribonucleotide-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	1.9e-97	53.7
SQF58066.1\|1528125_1530123_-\|tRNA	methionyl-tRNA synthetase	A0A1V0SHR2	Klosneuvirus	1.0e-86	35.2
SQF58067.1\|1530405_1531194_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_10

1539724 : 1545758

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF58072.1\|1539724_1540552_+	3'-exo-deoxyribonuclease	M1PSC0	Streptococcus_phage	2.2e-128	79.5
SQF58073.1\|1540625_1540982_-	arsenate reductase	M1PLC0	Streptococcus_phage	2.8e-40	66.7
SQF58074.1\|1541281_1541911_+	copper homeostasis protein	NA	NA	NA	NA
SQF58075.1\|1541957_1542350_-	hypothetical membrane associated protein	NA	NA	NA	NA
SQF58076.1\|1542376_1543240_-	corrin/porphyrin methyltransferase	M1PLC5	Streptococcus_phage	1.5e-114	74.7
SQF58077.1\|1543244_1543568_-	DNA replication initiation control protein	M1PFV3	Streptococcus_phage	1.3e-28	59.4
SQF58078.1\|1543971_1544211_-	Tpl protein	NA	NA	NA	NA
SQF58079.1\|1544229_1545105_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.8e-72	47.9
SQF58080.1\|1545122_1545758_-	thymidylate kinase	M1PSC7	Streptococcus_phage	2.0e-65	63.4

DBSCAN-SWA_11

1813343 : 1833106

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF58317.1\|1813343_1814564_-	transporter	A0A2H4PQR6	Staphylococcus_phage	1.6e-05	23.3
SQF58318.1\|1814574_1816557_-	DNA mismatch repair protein	A0A1B2LRQ5	Wolbachia_phage	2.3e-62	30.1
SQF58319.1\|1816651_1817797_-	DNA integration/recombination/inversion protein	A0A1X9I5Y5	Streptococcus_phage	2.7e-84	44.9
SQF58320.1\|1819040_1819688_-	Cro/CI family transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	4.4e-15	28.1
SQF58321.1\|1819853_1820051_+	Cro/CI family transcriptional regulator	A0A1X9I5U5	Streptococcus_phage	3.7e-18	72.3
SQF58322.1\|1820064_1820679_+	phage antirepressor protein	A0A1W6JPC3	Staphylococcus_phage	1.1e-36	42.0
SQF58323.1\|1820678_1820948_+	Prophage antirepressor	NA	NA	NA	NA
SQF58324.1\|1821203_1821536_+	phage protein	NA	NA	NA	NA
SQF58325.1\|1821532_1821754_+	Uncharacterised protein	NA	NA	NA	NA
SQF58326.1\|1821756_1821948_+	phage protein	NA	NA	NA	NA
SQF58327.1\|1821959_1822322_+	phage protein	NA	NA	NA	NA
SQF58328.1\|1822318_1822648_+	phage protein	NA	NA	NA	NA
SQF58329.1\|1822650_1822923_+	Uncharacterised protein	A0A1X9I5U9	Streptococcus_phage	3.6e-19	60.0
SQF58330.1\|1822923_1823784_+	replication protein	A0A1X9I6L2	Streptococcus_phage	2.5e-119	72.0
SQF58331.1\|1823801_1825298_+	DNA primase	Q9AZI5	Lactococcus_phage	1.1e-69	38.0
SQF58332.1\|1825928_1826195_+	phage protein	A0A1X9I5U4	Streptococcus_phage	8.9e-15	46.2
SQF58333.1\|1826460_1827063_+	Prophage ps3 protein 07	NA	NA	NA	NA
SQF58334.1\|1827052_1827382_+	Uncharacterised protein	NA	NA	NA	NA
SQF58335.1\|1827639_1827924_+	phage protein	NA	NA	NA	NA
SQF58336.1\|1828029_1828443_+	phage protein	A0A1S5S8W3	Streptococcus_phage	5.1e-09	30.8
SQF58337.1\|1828517_1828718_+	Uncharacterised protein	S6C469	Thermus_phage	5.1e-07	43.9
SQF58338.1\|1828805_1828979_+	phage protein	NA	NA	NA	NA
SQF58339.1\|1828953_1829337_+	phage protein	Q938L8	Temperate_phage	3.7e-14	41.7
SQF58340.1\|1829537_1830155_+	phage protein	NA	NA	NA	NA
SQF58341.1\|1830550_1833106_-	DNA mismatch repair protein mutS	A0A1V0SGG8	Hokovirus	6.8e-43	23.3

Anti-CRISPR protein detection

Acr_ID: LS483357.1|SQF57135.1|628453_628687_+|phage-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LS483357.1|SQF57135.1|628453_628687_+|phage-protein

628453_628687_+

77 aa aa

621147-662798

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
LS483357_1	TypeI	1.5\|562871\|33\|LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	630752-630720	1

1. spacer 1.5|562871|33|LS483357|PILER-CR,CRISPRCasFinder,CRT matches to LS483357 position: 630752-630720, mismatch: 1

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LS483357

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information