CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483366	Streptococcus salivarius strain NCTC7366 genome assembly, chromosome: 1	3 crisprs	DEDDh,csa3,RT,DinG,csn2,cas2,cas1,cas9,WYL,cas3	0	5	15	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483366_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483366_1

216481-216574

Orphan

Consensus_repeat	Method
TGTTCTAAAATTCGAGTTGGCAATTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483366_1

>merge|LS483366|1|216481-216574|CRISPRCasFinder
TGTTCTAAAATTCGAGTTGGCAATTAAGGGCTGTTCCCACCCTAAATGTTATCTTAGTCATAAGATGTGTTCTAAAATTCGAGTTGGCGATTAA

>LS483366|1|1|216481-216574|CRISPRCasFinder
TGTTCTAAAATTCGAGTTGGCAATTAA	GGGCTGTTCCCACCCTAAATGTTATCTTAGTCATAAGATG
TGTTCTAAAATTCGAGTTGGCGATTAA

Protein	Signature genes	Signature genes Name	Protein_function
LS483366.1\|SQF75097.1\|209639_210485_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379585
LS483366.1\|SQF75099.1\|210574_210880_-\|Protein-of-uncharacterised-function-(DUF2752)	unknown	unknown	gnl\|CDD\|378499
LS483366.1\|SQF75126.1\|222850_223264_+\|Protein-of-uncharacterised-function-(DUF2992)	unknown	unknown	gnl\|CDD\|378596
LS483366.1\|SQF75110.1\|214868_215045_+\|preprotein-translocase-SecE-subunit	unknown	unknown	gnl\|CDD\|236066
LS483366.1\|SQF75130.1\|224477_225320_+\|putative-ABC-transporter,-integral-membrane-protein	unknown	unknown	gnl\|CDD\|224428
LS483366.1\|SQF75105.1\|212331_214659_+\|penicillin-binding-protein-2A	unknown	unknown	gnl\|CDD\|273955
LS483366.1\|SQF75124.1\|220964_221420_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
LS483366.1\|SQF75095.1\|207935_209555_+\|Chaperonin-GroEL-(HSP60-family)	unknown	unknown	gnl\|CDD\|234573
LS483366.1\|SQF75125.1\|221476_222709_+\|acyl-CoA-thioesterase-1	unknown	unknown	gnl\|CDD\|370148
LS483366.1\|SQF75101.1\|210879_211212_-\|TM2-domain-containing-protein	unknown	unknown	gnl\|CDD\|377473
LS483366.1\|SQF75113.1\|215245_215785_+\|transcription-antitermination-protein	unknown	unknown	gnl\|CDD\|180161
LS483366.1\|SQF75133.1\|225803_226235_+\|Protein-of-uncharacterised-function-(DUF3021)	unknown	unknown	gnl\|CDD\|378668
LS483366.1\|SQF75115.1\|215917_216403_+\|phosphatidylglycerophosphatase-B	unknown	unknown	gnl\|CDD\|238813
LS483366.1\|SQF75103.1\|211396_212266_-\|RNA-pseudouridine-synthase-yhcT	unknown	unknown	gnl\|CDD\|223638
LS483366.1\|SQF75108.1\|214707_214860_+\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
LS483366.1\|SQF75117.1\|216601_217411_-\|cof-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
LS483366.1\|SQF75120.1\|217403_218171_-\|DeoR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
LS483366.1\|SQF75128.1\|223611_224478_+\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
LS483366.1\|SQF75131.1\|225338_225794_+\|transcriptional-regulator,-LytTr-family	unknown	unknown	gnl\|CDD\|335768
LS483366.1\|SQF75123.1\|218364_220866_+\|leucyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234743

Protein	Function_ID	Function_description	E-value
LS483366.1\|SQF75097.1\|209639_210485_-\|Uncharacterised-protein	gnl\|CDD\|379585	pfam14373, Imm_superinfect, Superinfection immunity protein. This family includes the E. coli bacteriophage T4 superinfection immunity (imm) protein. When E. coli is sequentially infected with two T-even type bacteriophage the DNA of the superinfecting phage is excluded from the host, into the periplasmic space. The immunity protein plays a role in this process.	1.45056e-07
LS483366.1\|SQF75099.1\|210574_210880_-\|Protein-of-uncharacterised-function-(DUF2752)	gnl\|CDD\|378499	pfam10825, DUF2752, Protein of unknown function (DUF2752). This family is conserved in bacteria. Many members are annotated as being putative membrane proteins.	1.20743e-06
LS483366.1\|SQF75126.1\|222850_223264_+\|Protein-of-uncharacterised-function-(DUF2992)	gnl\|CDD\|378596	pfam11208, DUF2992, Protein of unknown function (DUF2992). This bacterial family of proteins has no known function. However, the cis-regulatory yjdF motif, just upstream from the gene encoding the proteins for this family, is a small non-coding RNA, Rfam:RF01764. The yjdF motif is found in many Firmicutes, including Bacillus subtilis. In most cases, it resides in potential 5' UTRs of homologs of the yjdF gene whose function is unknown. However, in Streptococcus thermophilus, a yjdF RNA motif is associated with an operon whose protein products synthesize nicotinamide adenine dinucleotide (NAD+). Also, the S. thermophilus yjdF RNA lacks typical yjdF motif consensus features downstream of and including the P4 stem. Thus, if yjdF RNAs are riboswitch aptamers, the S. thermophilus RNAs might sense a distinct compound that structurally resembles the ligand bound by other yjdF RNAs. On the ohter hand, perhaps these RNAs have an alternative solution forming a similar binding site, as is observed with some SAM riboswitches.	1.36177e-39
LS483366.1\|SQF75110.1\|214868_215045_+\|preprotein-translocase-SecE-subunit	gnl\|CDD\|236066	PRK07597, secE, preprotein translocase subunit SecE; Reviewed.	2.68913e-10
LS483366.1\|SQF75130.1\|224477_225320_+\|putative-ABC-transporter,-integral-membrane-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	0.000352861
LS483366.1\|SQF75105.1\|212331_214659_+\|penicillin-binding-protein-2A	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
LS483366.1\|SQF75124.1\|220964_221420_+\|transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.11513e-12
LS483366.1\|SQF75095.1\|207935_209555_+\|Chaperonin-GroEL-(HSP60-family)	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
LS483366.1\|SQF75125.1\|221476_222709_+\|acyl-CoA-thioesterase-1	gnl\|CDD\|370148	pfam08840, BAAT_C, BAAT / Acyl-CoA thioester hydrolase C terminal. This catalytic domain is found at the C terminal of acyl-CoA thioester hydrolases and bile acid-CoA:amino acid N-acetyltransferases (BAAT).	6.04268e-26
LS483366.1\|SQF75101.1\|210879_211212_-\|TM2-domain-containing-protein	gnl\|CDD\|377473	pfam05154, TM2, TM2 domain. This family is composed of a pair of transmembrane alpha helices connected by a short linker. The function of this domain is unknown, however it occurs in a wide range or protein contexts.	7.80642e-12
LS483366.1\|SQF75113.1\|215245_215785_+\|transcription-antitermination-protein	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	3.28618e-82
LS483366.1\|SQF75133.1\|225803_226235_+\|Protein-of-uncharacterised-function-(DUF3021)	gnl\|CDD\|378668	pfam11457, DUF3021, Protein of unknown function (DUF3021). This is a bacterial family of uncharacterized proteins.	8.36896e-08
LS483366.1\|SQF75115.1\|215917_216403_+\|phosphatidylglycerophosphatase-B	gnl\|CDD\|238813	cd01610, PAP2_like, PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.	1.10007e-12
LS483366.1\|SQF75103.1\|211396_212266_-\|RNA-pseudouridine-synthase-yhcT	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.36425e-84
LS483366.1\|SQF75108.1\|214707_214860_+\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	2.86471e-18
LS483366.1\|SQF75117.1\|216601_217411_-\|cof-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.02348e-75
LS483366.1\|SQF75120.1\|217403_218171_-\|DeoR-family-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.14406e-68
LS483366.1\|SQF75128.1\|223611_224478_+\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.02834e-82
LS483366.1\|SQF75131.1\|225338_225794_+\|transcriptional-regulator,-LytTr-family	gnl\|CDD\|335768	pfam04397, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	1.56186e-21
LS483366.1\|SQF75123.1\|218364_220866_+\|leucyl-tRNA-synthetase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0

>LS483366.1|SQF75115.1|215917_216403_+|phosphatidylglycerophosphatase-B
MNYKRFYDRISAPLRSYAKVLEGLNKLITRTFYLLFPIFLIWVWLRNGWFVLSTTVLIMGGGFFLLSLGRSLYNRPRPYQTWAIQPLIKKDSLGKSFPSRHVFSATVIAMLALTLNPWLGGTMLFLAGALALLRVLGGVHYPSDVLAGYVIGILIGLLLYL
>LS483366.1|SQF75113.1|215245_215785_+|transcription-antitermination-protein
MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLENILRVEIPTQTVNVEKNGKVKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRQILISMGQTVDVFDTNIKVGDVVQIIDGAFMGQEGRVVEIENNKVKIMINMFGSETAAELELYQIAEL
>LS483366.1|SQF75110.1|214868_215045_+|preprotein-translocase-SecE-subunit
MRQTGSIFKVLKDTTWPDRKQRWHDFISVLEYTAFFTVIIYAFDELLSRAMSALINFF
>LS483366.1|SQF75108.1|214707_214860_+|50S-ribosomal-protein-L33
MAQKKASLACAECGSRNYSINVSSTPKPTRLEVNKFCKHCKKYTLHKETR
>LS483366.1|SQF75105.1|212331_214659_+|penicillin-binding-protein-2A
MTFFDNLKNKLFKEENSGKGKDSQPAEKSKNLQNKIKGLFAKKPDEVEQAVEDLDMSQESQETSRYQRSKQKKPIDTTKPLGKVQAFLSKFTLSPRNPIRRFWRRYHIGKILFILVAMLVLTVGSYLFYIAKTTNVSDLQDALKATTVIYDKEGNQAGSLSGQKGTYVELDAISDSLENAVIATEDRTFYENSGVNVKRFLLAIVSMGRFGGGSTITQQLAKNAFLTQEQTVTRKAKEFFLSLELTKKYSKQEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTVDEAATLAGMLKGPEIYNPIDNIQNATNRRNTVLANMVDDKKLSQADADSAAGVDMASRLDDTYQGTGDDYKYPSYFDAVIEEATKTYGLSEDEIVKNGYKIYTEMDANSQANMQQTYENTYLFPTSESDGSTAQSASVALDPTTGAVRGLVGRVGGTSDTTFRNFNYATQGKRSPGSTIKPLVVYAPALASGWSINKDLPNKPIDYNGYTPTNYGDIETEDIPMYQALANSYNVPAVYLFNQIGIQKGISYGQKFGLNFDNVPEELGISLGGGVTASPLQMAQAYATFANGGEMNTAYFITKIENASGDIIATHSKKSKRVISQSVANQMTSMMLGTFSNGSAVNANYTGYTMAGKTGTVQAEFNKDLTSDQWVIGYTPDVVMTTWIGFDKTDESHYLTGASSGTASTIFSYIAADVLPNTPGTEFTVENAYAADGQTLDYTADPNDSRNSSNKSWTDKASDVVNDVKDQASSLWDKITDSFSGLFR
>LS483366.1|SQF75103.1|211396_212266_-|RNA-pseudouridine-synthase-yhcT
MTLHVEIINPYPATTVKDLLETKLLIPRKIRHFLRTKKHVLINGETINWQSPVEKGDKISLTFDTEDYPEKIIPMGNASLVEPLYEDQHLIVVNKPEGMKTHGNEPTEIALLNHVSAYCGQTCYVVHRLDMETSGAVLFAKNPFILPILNRLLEDKKIQRQYWALAEGKFQTKETVYKDKIGRDRHDRRKRVVDPRKGQVAYTTITRLKAFKGASLVNCQLKTGRTHQIRVHLAHHGHAILGDPLYSHRPASRLMLHAHTLSFTHPLTLDKITVKASSNSFEQGLRNHK
>LS483366.1|SQF75101.1|210879_211212_-|TM2-domain-containing-protein
MNPVDQWITINAKYFPTEQVQYIRQRLEALPEQQLSMLYSISFQDPTMLLIISLLGGTLGIDRFLLGQIGLGVGKLLTCGGCGIWSIVDLFLIMDATRQSNAQKLFAVIG
>LS483366.1|SQF75099.1|210574_210880_-|Protein-of-uncharacterised-function-(DUF2752)
MKNYFTRLWAYHQRFFRLYLLVLVTVYGVYLLHLPTPLSLILRPFGLKAWSTGLTRASVRLLHLDWQGAWDYNPLIYPLVVYVLTYFFLFPIFSDKKIIRK
>LS483366.1|SQF75097.1|209639_210485_-|Uncharacterised-protein
MKQQDWIDFFQAVNGRNPSIQEMAEAAQKGEFVRETPKQTVEVTETVSQKETVETKQDSEVVEPAESAPSTEVVETAEKNVDSYDVAEEPLVDSSINERQTFQTPNLGQESPTTNFQEQINPIQGTTNKASNPFAEQANASFQQTNSTLNEPWKNPEKKSQTNLIMIAIATIPVILWALGMILLGIASDDLSTGLITALLSVIINFPLVVLLILPALLNKTDKKWPIFILSFLLGWTFIGWIILLAVSINTNKEAERIRQQQMMMQMAGQQGSSDTFNPFQ
>LS483366.1|SQF75095.1|207935_209555_+|Chaperonin-GroEL-(HSP60-family)
MAKDIKFSSDARAAMVRGVDTLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIEAAVATAVEELKAIAQPVANKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLDNPFILVTDKKISNIQDVLPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGATVITEDLGLELKDATMAALGQASKVTVDKDSTVIVEGAGSTEAIANRVNLIKSQLETTTSEFDREKLQERLAKLSGGVAVVKVGAATETALKEMKLRIEDALNATRAAVEEGIVAGGGTALVNVIAKVAELDLEGDDATGRNIVLRALEEPVRQIAYNAGYEGSVIIDKLKNSPVGTGFNAANGEWVDMVEAGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPETPAAPAMDPGMMGY
>LS483366.1|SQF75117.1|216601_217411_-|cof-family-hydrolase
MSNIRLIISDIDGTILTSNHQVDEQLIELMPKLEKANIPFVLASARSPLGMQPIAHKLGLHDNPIACYNGALVLEGDRAIIQHPVDKSEIQELLSYLSTDYPSVSVNIYSGKDWITNELDKWSQLEGSITGESPIIKELQDTVSDSEPPIHKLLLIDEPEVIQDLHQKLLSMDFPQTAFYLSKDNYLEVTAKHVSKEHALLEVAKYYDLPLEEVMTIGDNFNDSPMLALAGLGIAMGNAPEGVKETANLVTASNDEHGVAQAIKKHVLN
>LS483366.1|SQF75120.1|217403_218171_-|DeoR-family-transcriptional-regulator
MYQEQRLEKILTLLEERGNLSVKEMVDALGVSKDTVRRDFDCLSQRNLAQRTHGGILPVKNTTVLGFQERQKGLTEDKKKMADLALSLVKEQSLLFFDVSTLMLEVSQKLTKSVTVYSHSLDNALVLSGKEGIDFHLLGGRFYSKNRFYYSLHEAQLLQHLQFDLAFFGAASLSQGVVSYEDEEDVAVKQLAMQAARTKILIAESDKYEKHSKYILGKIEDFDYWITDKKPDPDLVESLKDKVTILYDGKDSNYE
>LS483366.1|SQF75123.1|218364_220866_+|leucyl-tRNA-synthetase
MSFYNHKEIEPKWQKYWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDDLDWPESIKDMQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHDLVDAITTPEQAEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGTGAVMAVPAHDERDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLNGLNKEEAIAKIVAWLEEKGFGQEKITYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIVAENNGALDKVYNETVKSVTEQIESMKFNTAIAQLMVFVNAANKEDKLYVGYAKGFIQLIAPFAPHLAEELWQTVAETGESISYIAWPTWDESKLVEDEIEIVVQIKGKVRAQLMVAKDLSREELQEVALANEKVKAEIDGKEIVKVIAVPNKLVNIVVK
>LS483366.1|SQF75124.1|220964_221420_+|transcriptional-regulator
MNKKELHKFNNRFNSFVLAFEQLKKAQHRNSIDKSITINEVHLIDLIGRNQPVNLVKLSELLEVSRSAITQSVRRLTKKDLVSFEFAPDNEKNKYLILSKKGVDVFNIHKEQQEHIETAIFSVLKNYSDEDLQMVMKLMDDVEKVWQELPW
>LS483366.1|SQF75125.1|221476_222709_+|acyl-CoA-thioesterase-1
MNIKIELISESDLADESFNIVIDGLKPREIYRVEMFLSDYYCINAPMLLAHDVLWKSTATFVSDKNGIIDISQTPSCSGSYEDIATMGLFFNAKPLTNRKKKLPNSLSKIPLLDHFFVEIKIIQGNTVVAKRTFTRYYMSSQISHQDIYEKHFQGRLFYDKKAIKAPALIIVSGSEGRIEKAQNIAQLLSSRGYICLAVAYFGLEGLPKHLERIPLECLVEAKDYLRQHPQVDSERIGIYGRSKGAELVLAEESIFNDVQCLVLNSPSDVVYEGIKGKWNSHTSSWTYLQKELPYQKFRLRDYLFSKLLKKSFPKDCSARIDIGQMHSPILLLGSTVDEIWDASSAIGDIVSYYKGHHITFKKYHETGHMLTVAHQPNHRYRKDWRLLMKESKDSWLATIHFFDRHLKKQ
>LS483366.1|SQF75126.1|222850_223264_+|Protein-of-uncharacterised-function-(DUF2992)
METISIGLTVYFEDGFWHGLFEQVYRESYQVCRVTFGQEPKDDEILEILQTQFTQLSFSPETTANQHVKIKNPKRLQRAVKKQVNQKVSSKSKELLQLQYEERKKISKHQSSVQKQLLKQEKFERKQQKRRDKNKGH
>LS483366.1|SQF75128.1|223611_224478_+|multidrug-ABC-transporter-ATP-binding-protein
MILQAKNISKRYGNHLAVDNIQLQFKRGTFNAILGPNGAGKSTTISMLIGLKQPTQGEIIYEPGTKIGVVFQTSVLDEMLTVRENLAIRARQYKGLKPNRVSSLIDRLGLSAFQKQKYGTLSGGQKRRVDIARALLSQPDILFLDEPTTGLDIQTRKSIWDLLYQLQREEGMTVVLTTHYLDEADEADQIYIVDHGKLIAQGSALDIKSQYAKNILKIRFKEIEQIESLKTSGMSVEQQSQLEYVFQPESEREAIDYLAQVRDRIAHFEFRPGTMDDAFIALTGREVR
>LS483366.1|SQF75130.1|224477_225320_+|putative-ABC-transporter,-integral-membrane-protein
MLALLKRNFLLYFRNRPGVFFSLLGALISFILYIIFLQKNLTDAWAQLPNSGPLLNNWLMSGTLAVTGITTSLAALTQLVKDREHQVDKDLYLSNQGKWRLPFSYLASAIIISFAMQVLMYVLMCSYFREVPKLYILPELLLIMMLSSLLSSLVNAILVYFFQSVDSLGKFATIVGTASGFLVGTYVPLGVLPDFAQLLMKCTPATYIAALYRQVLMKETLSETFKGQDNLLQEFQEKMGVQLKWQGLLTKENTYLIVLGGILLASILWIILVKRTSQKK
>LS483366.1|SQF75131.1|225338_225794_+|transcriptional-regulator,-LytTr-family
MKLRFEEKSDISAKDPCVVIQAERLSDQAREVMDYLEQFSVVNQVVIPIKTDDHLVMVKIDDIILAEIDKNVLTIYTVNNTYTMRETLTNFQHRINRRSFLQISRHAVMNIDHLESLSDSFSGNMMAKMTGGVKSSVSRKYVKSLMDYLGV
>LS483366.1|SQF75133.1|225803_226235_+|Protein-of-uncharacterised-function-(DUF3021)
MKRLIAYFVSGVRTGSFFYLALLLLGQLFPQLIYPKVSVGNILALFMMSGLMGMLSWILEEIDCISYRLRIILHFLLTAIVLTVTCLISGWYEALTNPAIWIVFISVYSIIWLYLIWQMHMRTQRINQALLHRRSQKKKSNKL

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Crispr_ID: LS483366_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483366_2

1244840-1244911

Orphan

Consensus_repeat	Method
GGACCTAAAAAGGTCCACTGAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483366_2

>merge|LS483366|2|1244840-1244911|CRISPRCasFinder
GGACCTAAAAAGGTCCACTGAACAGCCTCGCTTTTGGGTTTCTTGGCTCGGACCTAAAAAGGTCCACTGGAC

>LS483366|2|2|1244840-1244911|CRISPRCasFinder
GGACCTAAAAAGGTCCACTGAAC	AGCCTCGCTTTTGGGTTTCTTGGCTC
GGACCTAAAAAGGTCCACTGGAC

Protein	Signature genes	Signature genes Name	Protein_function
LS483366.1\|SQF76055.1\|1252660_1252945_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|168880
LS483366.1\|SQF76054.1\|1251437_1252664_-\|chloride-channel-protein-EriC	unknown	unknown	gnl\|CDD\|239654
LS483366.1\|SQF76049.1\|1247101_1248013_-\|tRNA-delta(2)-isopentenylpyrophosphate-transferase	unknown	unknown	gnl\|CDD\|234626
LS483366.1\|SQF76053.1\|1250962_1251310_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
LS483366.1\|SQF76056.1\|1253018_1254554_-\|chloride-channel	unknown	unknown	gnl\|CDD\|238504
LS483366.1\|SQF76045.1\|1242114_1243308_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
LS483366.1\|SQF76047.1\|1244915_1246568_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
LS483366.1\|SQF76044.1\|1241062_1242049_+\|transposase-InsI-for-insertion-sequence-element-IS30B/C/D	unknown	unknown	gnl\|CDD\|225382
LS483366.1\|SQF76051.1\|1249087_1249330_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483366.1\|SQF76046.1\|1243587_1244526_+\|biotin-[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|237010
LS483366.1\|SQF76050.1\|1248088_1248265_+\|putative-uncharacterized-protein-ORF-3	unknown	unknown	gnl\|CDD\|371431
LS483366.1\|SQF76052.1\|1249535_1250249_-\|phage-protein	unknown	unknown	gnl\|CDD\|309383
LS483366.1\|SQF76040.1\|1236085_1236226_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483366.1\|SQF76037.1\|1233112_1233283_-\|membrane-protein	unknown	unknown	gnl\|CDD\|131380
LS483366.1\|SQF76038.1\|1233670_1234774_-\|glycosyl-hydrolase-family-8	unknown	unknown	gnl\|CDD\|366548
LS483366.1\|SQF76043.1\|1239259_1239757_-\|transposase-like-protein	unknown	unknown	gnl\|CDD\|366234
LS483366.1\|SQF76041.1\|1236237_1237026_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483366.1\|SQF76048.1\|1246567_1247077_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
LS483366.1\|SQF76042.1\|1237028_1238180_-\|UDP-N-acetylglucosamine-2-epimerase	unknown	unknown	gnl\|CDD\|223458
LS483366.1\|SQF76039.1\|1234782_1236093_-\|N-acetyllactosaminide-beta-1,6-N--acetylglucosaminyl-transferase	unknown	unknown	gnl\|CDD\|133045

Protein	Function_ID	Function_description	E-value
LS483366.1\|SQF76055.1\|1252660_1252945_-\|chorismate-mutase	gnl\|CDD\|168880	PRK07248, PRK07248, chorismate mutase.	1.19569e-39
LS483366.1\|SQF76054.1\|1251437_1252664_-\|chloride-channel-protein-EriC	gnl\|CDD\|239654	cd03682, ClC_sycA_like, ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation competitiveness, and N2 fixation on Phaseolus vulgaris plants, due to its reduced ability for acid resistance. This family is part of the ClC chloride channel superfamiy. These proteins catalyse the selective flow of Cl- ions across cell membranes and Cl-/H+ exchange transport. These proteins share two characteristics that are apparently inherent to the entire ClC chloride channel superfamily: a unique double-barreled architecture and voltage-dependent gating mechanism. The gating is conferred by the permeating anion itself, acting as the gating charge.	5.2016e-172
LS483366.1\|SQF76042.1\|1237028_1238180_-\|UDP-N-acetylglucosamine-2-epimerase	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	6.87982e-174
LS483366.1\|SQF76053.1\|1250962_1251310_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.42285e-69
LS483366.1\|SQF76056.1\|1253018_1254554_-\|chloride-channel	gnl\|CDD\|238504	cd01031, EriC, ClC chloride channel EriC. This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked proton utilization. As shown for Escherichia coli EriC, these channels can counterbalance the electric current produced by the outwardly directed virtual proton pump linked to amino acid decarboxylation. The EriC proteins belong to the ClC superfamily of chloride ion channels, which share a unique double-barreled architecture and voltage-dependent gating mechanism. The voltage-dependent gating is conferred by the permeating anion itself, acting as the gating charge. In Escherichia coli EriC, a glutamate residue that protrudes into the pore is thought to participate in gating by binding to a Cl- ion site within the selectivity filter.	1.50923e-161
LS483366.1\|SQF76045.1\|1242114_1243308_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
LS483366.1\|SQF76047.1\|1244915_1246568_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
LS483366.1\|SQF76044.1\|1241062_1242049_+\|transposase-InsI-for-insertion-sequence-element-IS30B/C/D	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.40967e-88
LS483366.1\|SQF76046.1\|1243587_1244526_+\|biotin-[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	2.02309e-131
LS483366.1\|SQF76050.1\|1248088_1248265_+\|putative-uncharacterized-protein-ORF-3	gnl\|CDD\|371431	pfam11240, DUF3042, Protein of unknown function (DUF3042). This family of proteins with unknown function appears to be restricted to Firmicutes.	4.05312e-16
LS483366.1\|SQF76052.1\|1249535_1250249_-\|phage-protein	gnl\|CDD\|309383	pfam04233, Phage_Mu_F, Phage Mu protein F like protein. Members of this family are found in double-stranded DNA bacteriophages, and in some bacteria. A member of this family is required for viral head morphogenesis in bacteriophage SPP1. This family is possibly a minor head protein. This family may be related to the family TT_ORF1 (pfam02956).	3.5537e-18
LS483366.1\|SQF76037.1\|1233112_1233283_-\|membrane-protein	gnl\|CDD\|131380	TIGR02327, conserved_hypothetical_protein, conserved hypothetical integral membrane protein. Members of this protein family are small, typically about 80 residues in length, and are highly hydrophobic. The gene is found so far only in a subset of the Firmicutes in association with genes of the ATP synthase F1 complex or NADH-quinone oxidoreductase. This family includes ywzB from Bacillus subtilis; pfam06612 describes the same family as Protein of unknown function DUF1146.	0.00101857
LS483366.1\|SQF76038.1\|1233670_1234774_-\|glycosyl-hydrolase-family-8	gnl\|CDD\|366548	pfam01270, Glyco_hydro_8, Glycosyl hydrolases family 8.	2.46372e-19
LS483366.1\|SQF76043.1\|1239259_1239757_-\|transposase-like-protein	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	0.000721202
LS483366.1\|SQF76048.1\|1246567_1247077_-\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	1.04341e-72
LS483366.1\|SQF76049.1\|1247101_1248013_-\|tRNA-delta(2)-isopentenylpyrophosphate-transferase	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	1.89277e-134
LS483366.1\|SQF76039.1\|1234782_1236093_-\|N-acetyllactosaminide-beta-1,6-N--acetylglucosaminyl-transferase	gnl\|CDD\|133045	cd06423, CESA_like, CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.	1.32005e-53

>LS483366.1|SQF76046.1|1243587_1244526_+|biotin-[acetyl-CoA-carboxylase]-ligase
MKTYEHVYDILSKSPDFVTGESLAKSLGVSRTAIWKAIQTLQEQGIDITSVRKKGYYLEKGDILLPQDISKQLNIPVYFNPDSNSTQLDAKHGMEKNNPTPALYLASSQKAAKGRFERHFFASPQGGIYMSIHLKPNCHFEELPPYTMMAAAAIVKAIQRLTGINTEIKWVNDIYLNNKKMAGILTEAISSIESGRITDVIIGVGLNFSISDFPEELANKATSLFTSEKPSITRNQLISEIWRLFLTIPTSDLVKVYKEKSLVLDKQVTFEQAGKTYTGVAKEIGDKGQLLVLTDDGREKWLTAGEVSLTSW
>LS483366.1|SQF76045.1|1242114_1243308_-|methionine-adenosyltransferase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPDAHVAAETAVYTGSVHVFGEVSTTAYVDINRVVRDTIAEIGYNNAEYGFAAESVGVHPSLIEQSPDIAQGVNEALEVRGTGDQDPLDLIGAGDQGLMFGFAIDETPEFMPLPVSLSHKLVKKLADLRKSGEISYLRPDAKSQVTVEYDENDQPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPAEYLDDETKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVANPVSVRVDTFGTATVAESKLEAAVRDLFDLRPAGIIQMLDLKRPIYRQTAAYGHMGRTDIDLPWEKLDKVDALKTAVEA
>LS483366.1|SQF76044.1|1241062_1242049_+|transposase-InsI-for-insertion-sequence-element-IS30B/C/D
MSYHHFTIDERESILIYRTQGLNFSQIAKLLHRHPSSISREWKRHTKSGAYSPNHAQESYHNAKSHCGRKRMLEIDHNLSNTIKHLFLDYQWSPEEIEGRLRLEYGKTVVSYQTIYRAIYRGHFEDNSLSHGARGVIRKLRHRGKTRHTKGHVENRGKISISHTIHGRPEEANNRTRIGDWEADTVAGKIGKACLVTLTDRYSRFLKIKKVAVKKSKLVIEAMVKMLEPLTKYTVTPDRGKEFTYHQKLSDQLNIEVYFPDPHAPWQRGTNENTNGLLREYFPKGSDLTLVDDQTIQLWENKLNNRPRKCFNWKTPYEVFYGESMHLI
>LS483366.1|SQF76043.1|1239259_1239757_-|transposase-like-protein
MITLIQRQFEASKPMAKCYTDVTGFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLKQAIVDHIDYYNNKRIKIKLKLSSQGHITKRGNPYTRNILFKCIHNIASASHTNLCHIADFYEKRKRQSQVTSTKPHTIASIHRLIRTMYYLITHNKLYDYTSIQNR
>LS483366.1|SQF76042.1|1237028_1238180_-|UDP-N-acetylglucosamine-2-epimerase
MGKLNIMVVFGTRPEAIKMAPLILELKKHQETINTITVVTAQHRQMLDQVLDTFEIVPDYDLDIMGKNQSLQEITSKILSKFDPVVRKEKPDLVLVHGDTTTTFAAGLVAFYNKVSIGHVEAGLRTYDKYSPYPEEMNRQMTDSFSDLYFAPTQESKANLLSENHKKEAIYVTGNTAIDALKLTVKDNYYHEVLDKIDDRRKIILVTMHRRENQGEPMHRVFKTLRLMVDNHPEIEVVYPVHLSPSVQAVAKEVLGDHDRIHLIAPLDVFDFHNLASRSYFIMSDSGGVQEEAPSLGKPVLVLRDTTERPEGVKAGTLKLVGTDTKKVKEAMESLLTDEALYKEMSEAPNPYGDGKAAERIVQAIKVYFNLADSVSEFHEGGD
>LS483366.1|SQF76041.1|1236237_1237026_-|Uncharacterised-protein
MKKDKKVWYWILFLIFFEALLFSYCYQFNPEYFMFESILLVLGIGAVCFLSELLITWMIILSFALSIFILVSGVVYISLQDTLVLIFSFPLLLGILSKIKSYFYKYISSVQIEERKARKSYQAVLKEIKLNENKFINALLIHYSHEEQFFELDPREYNHLITSIYLKISKQLNRFEQIFYVADGSFLILSKNDSRNLNDFYKDSLERQLKGITFDWGNNHQSIQFQTGFLEINKNNLKKFDDYSELISNLNRQLETDIIVEY
>LS483366.1|SQF76040.1|1236085_1236226_-|Uncharacterised-protein
MTITNLFFVFALSISLLFVITFIVLFIQYTIIYERVSHNFKAVEHG
>LS483366.1|SQF76039.1|1234782_1236093_-|N-acetyllactosaminide-beta-1,6-N--acetylglucosaminyl-transferase
MVSQFLMIFTLVSIWISLIWGVVILVSGVHFWLKHSDFKVDKKALPYYPKVTIVVPAHNEDVVIAQTAKAILNLNYPHDKVELLLFADNCSDSTYEECLSVQALPEYEGRNITIINRKGTGGKAGVLNDALKMAEGDYICIYDADAMPEKNALYFLVKEVLKDPERRVAAFGRNKTRNAKQNFLTRCINQEIVVTQRVHHVGMWHLFKIGRIPGTNFIIQTDFVKSIGGWRNGALTEDTDISFKIMQSGKLIALAYNSEAFQQEPETLKSYYMQRKRWAKGNYEVVLSNFKHLFGKGNWRVKLEVANYSCIFFWFNGAIVLSDLIFFANVLAIILHPFFPTIQIPFAFDASNIYIAQLMLFNWLLMIGLYLLQINVALASQFGQATSKQVWLAILSYFSYAQLFIIVSLDSLWSIIMDKVLHREGTTWVKTKRFAE
>LS483366.1|SQF76038.1|1233670_1234774_-|glycosyl-hydrolase-family-8
MKIKYFKYFWFIVTLGLFVFLMFSVRIKTKTDIRNRIYQQWERHFVVKDGNEAYIKTTNDKDKDIVLSESQSYGMLITVRAAQKGLASQQDFERLYKYYLSHRIEGSQLMSWEQIVQKSSKNVDEHNATDGDLYIAYALIEASKQWPSQKDEYQTQSKAILQDILKYNYNENTGILTVGNWANRDSKYYNLMRTSDALPKQFQSFYEVTKDKKWLSISDKMLSSLETISSQTETGLIPDFIWVDQSGVRNVKPHTISSQFDSTYSYNACRLPYNLTQSNDEKSQRVLSKLLDFFMTQKNIFSNYNLDGNFLDDHQAACFKAPIALAADKDSGYLKLVQQNKIVFMQNLPVNNYYDSAIITLVTMEFF
>LS483366.1|SQF76037.1|1233112_1233283_-|membrane-protein
MLISLFDWAKIIKNPIENTGKLKLFLLFISIALGYLIISFILSVLAFGQNMASSIS
>LS483366.1|SQF76047.1|1244915_1246568_-|DNA-polymerase-III-subunit-gamma/tau
MYQALYRKYRSQTFGEMVGQKVISTTLRQAVESGKISHAYLFSGPRGTGKTSAAKIFAKAMNCPNQVDGEPCNHCDICRDITNGSLEDVIEIDAASNNGVDEIREIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHKIPATILSRVQRFEFKSIKQGAIKEHLASILEKEGLTFDDEALTIIARRAEGGMRDALSILDQALSLSPDNHVSQAVAEEITGSIGLTALDSFVANVRNQETTQALSNLETLFDNGKSMSRFATDLLEYFRDLLIVKAGGENSHHSPLFEENLSLEQDRLFQLIDLVTSALPEIKTGTHPKIYAEMLTIKLSETHTQASQEIPGNLQEELDSLRREVEGLRKALKEGKAQGEVAPTRKAKPAYQYKVDREKILTIMRETMENPQKSRQCLDALKATWPEILDSISPQNRALLNGSEPVLANQENAILAFNAAFNAEQVMKRSDLNDMFGNIMSSAAGFSPNIMAVPKAEFEKLRTEFARSLKSKEELEKEDREEYIPQELDFLSDVVEIED
>LS483366.1|SQF76048.1|1246567_1247077_-|GAF-domain-containing-protein
MVVMTNEEKKSAYELMLAQAKVLFANEDNAMANFSNASALLNTTLPNSVFTGFYLMDNVKNELILGPFQGNVSCVRIALGKGVCGQSAAENRTLIVEDVTKHANYIACDSAARSEIVVPMVKDGKLVGVLDLDSHQVGDYNDVDQDYLEAFIKILLEKTELTFGMFEVN
>LS483366.1|SQF76049.1|1247101_1248013_-|tRNA-delta(2)-isopentenylpyrophosphate-transferase
MKTKLIVVAGPTAVGKTALGIELAKRFNGEIISGDSQQVYRQLNIGTAKATPEEQAAAVHHLIDVRDVDESYSAYDFVIEAEVAISDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGQVDQEQVLAYRSELEQLSDQELFEKIDRLGIEIKEINRRRAIRALELHRFSENLENTETTYDPFLIGLDDKRSLIYDRINTRVDKMVEHGLLEEAMWLYENYPNAQSARGIGYKELFPYFAGNQSLDEALEKLKQNTRRFAKRQLTWFRNRMTVKFYQISSPEYPKNVVQDLELFLNEREGEKVGQS
>LS483366.1|SQF76050.1|1248088_1248265_+|putative-uncharacterized-protein-ORF-3
MAKKHSFAKGLATGVLGTAATVAGAVFAVKKTIIEPEEKKLAFIEENRKKAARRRVSR
>LS483366.1|SQF76051.1|1249087_1249330_-|Uncharacterised-protein
MAMSYSQNLKELKQLCEYLWDADFEVDGKTVSILPESENNIVVVYDGKEIIVKSFDELIELKLDGVTLPKLMENVEVRYA
>LS483366.1|SQF76052.1|1249535_1250249_-|phage-protein
MSVGRQELLIQELELELLVLSEGERQLTNDYLMNGYKSEIVRGSLLDQTVPNKKTLERYMTTAVNANFEGAKWSERIWGRNAQLRQLVRTEVTRALIRGNNGLTIARRIRKHMDVLRTNAERLGITEHARVQTLAQKDIMKENGFEYFKLMPDSRACDYCKQVGRDTEKEPVPIDKIDSGLNAPPMPPYCHCAVAEVYLDKEKLHKINENGIVQVDEVINGTPHPVGEARKVIQHNA
>LS483366.1|SQF76053.1|1250962_1251310_-|50S-ribosomal-protein-L19
MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGTRERIQIFEGVVISRKGQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRK
>LS483366.1|SQF76054.1|1251437_1252664_-|chloride-channel-protein-EriC
MKVKQLSDSQGLSYLHLVMLSLYAILLGVLVGLIDAVFGRVLIGLSEYRDQHIFYLVPALPLAGLLIVYLYQKLAGKAAQGMGLIFKVGHNEEDQVPLRLIPLVTVTTWLTHLFGGSAGREGVAVQLGATVSHAFSRYFKIPNASRIFLTMGMAAGFGGLFQTPIAATFFALEVLTLGQLSLPILVPTLIASFVASTTSHLLGLEKFSHFVSDSLTIDLETFVKLALLGLVFGVAGNLFAYLLSVAKKKVASLLPNPYYRVLLGSVVLTCLLLILWKGRYTGLGTNLIALSVGGGTIYPLDWLLKLLLTVFTLSLGFQGGEVTPLFAIGASLGAVLAPVLGLPIPLVAGLGYLSVFGSSTNTLLAPIFIGVEVFGPANALPYAIVMAFAYLINHKTSIYGQQKMLEMQ
>LS483366.1|SQF76055.1|1252660_1252945_-|chorismate-mutase
MDLNEIRQQIDTVDNEIVALLEERMKLVTRVSAYKQRTGKAIYDPEREQALLDKVGASVLNSEYKEAIVASFADIMKHSRIYQASKLEKSRHLE
>LS483366.1|SQF76056.1|1253018_1254554_-|chloride-channel
MNEIERDFRTQSQHLLWSVWRGLLVGVTAGAVVSLFRWLIAKGAAFSVAIYEDALRNPLLILGIVLVNLLIALFIGYLIKQEKDIKGSGIPHVEGELMGLLHPSWWSVLWRKFLGGVLGISMGLMLGREGPSIQLGAMTAKGLAEGLKLSAREKRVLIAAGAAAGLSAAFNAPIAGLLFVVEEIYHHFSRHVWVTALTASLVANAVSLRIFGQVPVLAMTEKLPVFPLKDYWILIVLGIFLGVLGYGYEWVVLRIGKVYQGLGKIFHLPSHFHGLLAVLFIIPIGLYFPYLLGGGNELILALNGLHPALTVAILYLAIRFIWSMLSFGSGFPGGIFLPILTLGALSGSVFAAAFENLGFLQVSQFPIFIILGMAGYFGAVSKAPLTAMILVTEMVGDLHQLMTIGVVTLIAYLVMDFMGGEPVYEAMLHNLIAHEPKQVDNIPTMIDLPVTDSLAGRLVKDLTLPDGVLISTQIFQDQSEVVHGDTRLKAGATLYLVVNESNISQVRKLFL

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Crispr_ID: LS483366_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483366_3

1452052-1452612

TypeII

Consensus_repeat	Method
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CRISPRCasFinder
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CRT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	PILER-CR

8 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of LS483366_3

>merge|LS483366|3|1452052-1452612|CRISPRCasFinder,CRT,PILER-CR
ACTGTACAGTCACTTAAATCTTAAAGTACAAAAAAGGGGTTGTGCTTTCCGTCCAAAACTGCTCAGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACAGCGTGTTGATCCGTTAGCTTTAAAATCAAGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACACATCATCAATTCTGTATCAGCATTAATGCGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACCAACGGTGCTGTCTGTGAACTTGTTTTCTGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACAGACAATTAAGCTAAATTCAGCCCCGCCGTGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACAGTAGTGCACCCACCCAGGACGTTTCAGCGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACAGACGTTAGCGCGTATCAGCCTGGCGACTTGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACACCTCTTGATGTTGAAGGAAAGGTGAAAATGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

>LS483366|3|3|1452052-1452612|CRISPRCasFinder
ACTGTACAGTCACTTAAATCTTAAAGTACAAAAAAG	GGGTTGTGCTTTCCGTCCAAAACTGCTCA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGCGTGTTGATCCGTTAGCTTTAAAATCAA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	ACATCATCAATTCTGTATCAGCATTAATGC
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CAACGGTGCTGTCTGTGAACTTGTTTTCT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGACAATTAAGCTAAATTCAGCCCCGCCGT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGTAGTGCACCCACCCAGGACGTTTCAGC
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGACGTTAGCGCGTATCAGCCTGGCGACTT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	ACCTCTTGATGTTGAAGGAAAGGTGAAAAT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

>LS483366|3|1|1452052-1452612|CRT
ACTGTACAGTCACTTAAATCTTAAAGTACAAAAAAG	GGGTTGTGCTTTCCGTCCAAAACTGCTCA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGCGTGTTGATCCGTTAGCTTTAAAATCAA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	ACATCATCAATTCTGTATCAGCATTAATGC
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CAACGGTGCTGTCTGTGAACTTGTTTTCT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGACAATTAAGCTAAATTCAGCCCCGCCGT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGTAGTGCACCCACCCAGGACGTTTCAGC
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGACGTTAGCGCGTATCAGCCTGGCGACTT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	ACCTCTTGATGTTGAAGGAAAGGTGAAAAT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

>LS483366|3|1|1452117-1452612|PILER-CR
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGCGTGTTGATCCGTTAGCTTTAAAATCAA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	ACATCATCAATTCTGTATCAGCATTAATGC
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CAACGGTGCTGTCTGTGAACTTGTTTTCT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGACAATTAAGCTAAATTCAGCCCCGCCGT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGTAGTGCACCCACCCAGGACGTTTCAGC
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AGACGTTAGCGCGTATCAGCCTGGCGACTT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	ACCTCTTGATGTTGAAGGAAAGGTGAAAAT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
LS483366.1\|SQF76247.1\|1450151_1450283_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483366.1\|SQF76253.1\|1455137_1458557_-\|CRISPR-associated-endonuclease,-Csn1-family	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
LS483366.1\|SQF76240.1\|1444271_1444712_-\|gas-vesicle-protein	unknown	unknown	gnl\|CDD\|378938
LS483366.1\|SQF76244.1\|1447095_1447359_-\|stress-responsive-transcriptional-regulator-PspC	unknown	unknown	gnl\|CDD\|224894
LS483366.1\|SQF76256.1\|1461673_1462288_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|378302
LS483366.1\|SQF76248.1\|1450288_1451191_+\|putative-permease	unknown	unknown	gnl\|CDD\|223773
LS483366.1\|SQF76242.1\|1445247_1446039_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
LS483366.1\|SQF76255.1\|1459764_1461426_-\|sulfate-permease-family-protein	unknown	unknown	gnl\|CDD\|183265
LS483366.1\|SQF76245.1\|1447424_1447865_-\|SprT-family-metallopeptidase	unknown	unknown	gnl\|CDD\|235290
LS483366.1\|SQF76259.1\|1463766_1464129_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483366.1\|SQF76257.1\|1462383_1463025_-\|lipase/acylhydrolase-family-protein	unknown	unknown	gnl\|CDD\|238879
LS483366.1\|SQF76249.1\|1451190_1452006_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226214
LS483366.1\|SQF76254.1\|1458742_1459678_+\|putative-integrase-protein	unknown	unknown	gnl\|CDD\|225382
LS483366.1\|SQF76246.1\|1447851_1449984_-\|protein-tex	unknown	unknown	gnl\|CDD\|225094
LS483366.1\|SQF76251.1\|1453724_1454048_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LS483366.1\|SQF76250.1\|1452675_1453728_-\|CRISPR-associated-protein-Cas7	csn2	cd12217_csn2_CAS-II-A	gnl\|CDD\|213410
LS483366.1\|SQF76241.1\|1444724_1445123_-\|methyl-accepting-chemotaxis-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227109
LS483366.1\|SQF76258.1\|1463051_1463663_-\|CAAX-amino-protease-family-protein	unknown	unknown	gnl\|CDD\|376806
LS483366.1\|SQF76243.1\|1446038_1446968_-\|HPr(Ser)-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235459
LS483366.1\|SQF76252.1\|1454049_1454961_-\|CRISPR-associated-protein,-Cas1-family	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
LS483366.1\|SQF76255.1\|1459764_1461426_-\|sulfate-permease-family-protein	gnl\|CDD\|183265	PRK11660, PRK11660, putative transporter; Provisional.	0
LS483366.1\|SQF76253.1\|1455137_1458557_-\|CRISPR-associated-endonuclease,-Csn1-family	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	0
LS483366.1\|SQF76240.1\|1444271_1444712_-\|gas-vesicle-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	4.40747e-08
LS483366.1\|SQF76244.1\|1447095_1447359_-\|stress-responsive-transcriptional-regulator-PspC	gnl\|CDD\|224894	COG1983, PspC, Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms].	4.4796e-18
LS483366.1\|SQF76256.1\|1461673_1462288_-\|Uncharacterised-protein	gnl\|CDD\|378302	pfam09911, DUF2140, Uncharacterized protein conserved in bacteria (DUF2140). This domain, found in various hypothetical prokaryotic proteins, has no known function.	0.000272037
LS483366.1\|SQF76248.1\|1450288_1451191_+\|putative-permease	gnl\|CDD\|223773	COG0701, COG0701, Predicted permeases [General function prediction only].	1.62683e-77
LS483366.1\|SQF76242.1\|1445247_1446039_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.24377e-99
LS483366.1\|SQF76245.1\|1447424_1447865_-\|SprT-family-metallopeptidase	gnl\|CDD\|235290	PRK04351, PRK04351, SprT family protein.	1.31587e-85
LS483366.1\|SQF76257.1\|1462383_1463025_-\|lipase/acylhydrolase-family-protein	gnl\|CDD\|238879	cd01841, NnaC_like, NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases. E. coli NnaC appears to be involved in polysaccharide synthesis.	6.74165e-36
LS483366.1\|SQF76249.1\|1451190_1452006_+\|membrane-protein	gnl\|CDD\|226214	COG3689, COG3689, Predicted membrane protein [Function unknown].	7.08107e-106
LS483366.1\|SQF76254.1\|1458742_1459678_+\|putative-integrase-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	5.46217e-105
LS483366.1\|SQF76246.1\|1447851_1449984_-\|protein-tex	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
LS483366.1\|SQF76251.1\|1453724_1454048_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.0368e-27
LS483366.1\|SQF76250.1\|1452675_1453728_-\|CRISPR-associated-protein-Cas7	gnl\|CDD\|213410	cd12217, Stu0660_Csn2, Stu0660-like CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. This family of Csn2 proteins includes Stu0660, the proteins are larger than other (canonical) Csn2 proteins as they have an additional alpha-helical C-terminal domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.34795e-129
LS483366.1\|SQF76241.1\|1444724_1445123_-\|methyl-accepting-chemotaxis-like-domain-containing-protein	gnl\|CDD\|227109	COG4768, COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only].	3.30131e-33
LS483366.1\|SQF76258.1\|1463051_1463663_-\|CAAX-amino-protease-family-protein	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	9.70303e-10
LS483366.1\|SQF76243.1\|1446038_1446968_-\|HPr(Ser)-kinase/phosphatase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	2.9141e-169
LS483366.1\|SQF76252.1\|1454049_1454961_-\|CRISPR-associated-protein,-Cas1-family	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.12644e-134

>LS483366.1|SQF76249.1|1451190_1452006_+|membrane-protein
MLRFLILSGYFELVMYLQVSGKLNQYINIHYSYLAYISMVLSFILAVVQLIVWMKQMKVHSHLSGRVAKVASIVLLAFPVLTGLLVPTVTLDANTVSAKGYHFPLAAGSDSNQADQEGTTIQYLKPDTSSYFTSSAYEKEMTRELAKYKGRETIQITTENYMEVMELIYLYPNDFVGKKVTYTGFVYNDPQTKGYQFIFRFGIIHCIADSGVYGLATTGSDQTFKDNTWVKVTGTITVDYYQNLKQSLPILNLTEVKEVGQPDNPYVYRVF
>LS483366.1|SQF76248.1|1450288_1451191_+|putative-permease
MAIFHQLPDSVLQLLAVFLSIIIEALPFVLLGSILSGFIEVFVTPEKVQNFLPKNKVLAILFGTLIGFIFPSCECGIVPIITRFLEKKVPSYTAIPFMATAPIINPVVLFATYTAFGNSWYYVLLRFVGAFLIAMILGILLGFVVDDQILKDNRKVSHVHDYSGLSAGKKTFQALVHAVDEFFDTGRYLIFGSLVAASMQTYLPTRILTTIGHNSVTAILIMMLLAFILSLCSEADAFIGASLLSSFGVAPTVAFLIIGPMVDIKNLIMMKHQFKTRFVGLFVGTASLATIIYCLVLGVI
>LS483366.1|SQF76247.1|1450151_1450283_+|Uncharacterised-protein
MAVIQKKTNELESMMASFAAIPDFEKAGTDPKKDKRLQEDKKK
>LS483366.1|SQF76246.1|1447851_1449984_-|protein-tex
MENRNLETLAQELGLKKQQVETVLELTAEGNTIPFIARYRKEKTGNLDETQIKAIIDMDKSLTALQDRKETVLAKIEAQGKLTDQLKAAIEAAEKLADVEELYLPYKEKRRTKATVAREAGLFPLARLILQNSPNLKAEAEKLTSEAFPTADKALAGAVDILVEAFSEDNSLRSWTYNEIWNNSDITSTLKDQSLDEKETFKIYYDFEDKVSKLQGYRTLALNRGEKLGVIKVAFKHNLEKMHRFYSARFKQKNDYIEEVINQSLKKKIIPAMERRIRSELTEAAEDGAIQLFSQNLRSLLLVSPLKGKMVLGFDPAFRTGAKLAVVDQTGKLITTQVIYPVAPASQAKIAQAKKDLADLIKKHAIEIIAIGNGTASRESEAFVAEVLKDFPETSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGVGQYQHDVSQKKLSENLDFVVDTVVNQVGVNVNTASSTLLSHVSGLNKTISENIVAYREENGEIASRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPESYPAVKALFKQLAITDLDDSAKAKLKALNLKETAEGLGLGQETLKDIIADLLKPGRDLRDDFEAPVLRQDVLELKDLSVGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKSFVNHPSQVVSVGDLVTVWVSKVDLEHEKLNLSLVNPRESN
>LS483366.1|SQF76245.1|1447424_1447865_-|SprT-family-metallopeptidase
MNLTDYVKTVSIEDFGWEFKHQALWNKRLRTTGGRFFPKDGHLDFNPKLYEEHGLETFRKIVRHELCHYHLYFQGKGYKHADRDFKDLLAKVDGLRYAPKMQGQEENYYLYQCQSCGHTYRRKRRVNTQKFGCGLCRGKLIFLNQS
>LS483366.1|SQF76244.1|1447095_1447359_-|stress-responsive-transcriptional-regulator-PspC
MSNRFYKTRKNRLVAGVVAGLADKFGWDLALARILAIILMVSTQFGIFLYLVLAFLLPYKEDIYPEIKLKDGRKRKNAEPVEDEWNW
>LS483366.1|SQF76243.1|1446038_1446968_-|HPr(Ser)-kinase/phosphatase
MTVTVKMLVDKLKLKVIYGNEKLLSKPITTADISRPGLEMTGYFDFYSPERIQLVGMKEWSYLKTLTDHNRYSVFSNMFKEETPAVIVARGLDIPEEMYRAAKENGVAVLQGRNGTSSLSGDMSWYLNAQLAERTSVHGVLVDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAVRNSSQVQLAIYLENFEDGKVFDRLGNGNEEIELQGVKIPRVRIPVKTGRNVSVVIEAAAMNYRAKQMGFDATKTFEERLTNLISKNGED
>LS483366.1|SQF76242.1|1445247_1446039_-|prolipoprotein-diacylglyceryl-transferase
MFATIDPIALRLGPISIHWYAICIVSGLLLAVYLAQRWAPEKGIDPENILDFILLAFPIAIVGARLYYVIFQWSYYSQNPSEIFAIWNGGIAIYGGLIAGAAVLYWFAKRHAIAVLDFLDIAAPGVMIAQSIGRWGNFINQEAYGKAVSHLNYVPEFIRQQMYIDGSYRVPTFLYESLWNLVGFIIILGLRRFNKKLRQGDVTSFYLIWYGLGRFVIEGMRTDSLMFVGLRVSQWVSIAIIILGATLLYLRKQRPEADYKMKN
>LS483366.1|SQF76241.1|1444724_1445123_-|methyl-accepting-chemotaxis-like-domain-containing-protein
MAEIAFLIIAIALAAFLIALIPTLLRTRHVVKEVEETVAVLRTDINVTLHQTNEILAKANVLVEDVNEKVQTIDPLFVAVAELSESVSDLNTEARYLGAKASAAGASVGKAGSAFAIGKVASKLFGKKDKKK
>LS483366.1|SQF76240.1|1444271_1444712_-|gas-vesicle-protein
MSKFLNTLIIGVASGAAAAYFFTTEKGKAVKARIDEEIASFKEDPKAYQNQVVEKASDYKDLAVDTFQDYKTKFENGDITADDLTKAVQEKTAQVADFAKESFELIKEKTAQVTPEQADVEAETKAIVDDIVIDIKDISEEATEAK
>LS483366.1|SQF76250.1|1452675_1453728_-|CRISPR-associated-protein-Cas7
MKFFVQHPYKERIELNIGAITQIVGQNKELKYYIWQILSWYFGGKKYSSDDLSIFDYEEPTILDESGEIVKRSSYHYIEISSFKDLLEQMEYKKGTLAHGYLGKIVNQVDIVAHLEKINEQVELIEGAMNQHINLNSGKVEYHLENRSLTLDQLLSKNFSPFFAIENKNLSFEWVSNTDKLSLFLEMLDRLLSQTTEKYLIVLKNIDSFISEESYDSFYKQIGQLVKKYPNLNLILFPSNQGYLKIDEENSRFVNILSDQVEHLYDIEFMYDRVKKHYPSNNFPPREGFRKSLENVTPYLLTKMLRQPSLTLVDSVILNILNQLFQFNYRIRYSQTPDEELLHRYLESKN
>LS483366.1|SQF76251.1|1453724_1454048_-|CRISPR-associated-endoribonuclease-Cas2
MRYEALRLLCFFDLPMESKDEKRIYRNFRKELISNGFEMLQFSVYYRTCPNRSFANKFYKKLKMSNLPAGNVRLLAVTEKQFSEMTLIIGGKTKQEEIVSDNKLVVI
>LS483366.1|SQF76252.1|1454049_1454961_-|CRISPR-associated-protein,-Cas1-family
MTWRVVHVSQSEKMRLKLDNLLVQKMGQEFTVPLSDISIIVAEGGDTVVNLRLLSALSKYNIALVVCDNEHLPTGIYHSQNGHFRAYKRLKEQMDWSQKQKDKAWQIVTYYKINNQEDVLAMFEKSLDNIRLLSDYKEQIEPGDRTNREGHAAKVYFNELFGKQFVRVTQQEADVINAGLNYGYAIMRAQMARIVAGYGLNGLLGIFHKNEYNQFNLVDDLMEPFRQIVDVWVYDNLRDQEFLKYEYRLGLTDLLNAKIKYGKETCSVTVAMDKYVKGFIKYISEKDSSKFHCPVVSSLEWRK
>LS483366.1|SQF76253.1|1455137_1458557_-|CRISPR-associated-endonuclease,-Csn1-family
MSDLVLGLDIGIGSVGVGILNKVTGEIIHKNSRIFPAAQAENNVERRTNRQGRRLTRRKKHRRVRLNHLFEESGLITDFTQVSINLNPYQLRVKGLTDELSNEELFIALKNMVKHRGISYLDDASDDGNSSVGDYAQIVKENSKQLETKTPGQIQLERYQKYGQLRGDFTIEEDGKKHRLINVFPTSAYRAEALRILQTQQEFNPQITDEFINSYLQILTGKRKYYHGPGNEKSRTDYGRYTTKKDSEDEYLTLDNIFGILIGKCTFYPEEYRAAKASYTAQEFNLLNDLNNLTVPTETKKLSEEQKNKIITYVKNEKAMGPAKLFKYIAKLLSCDVADIKGYRIDKSDKAEIHTFEAYRKMKTLETIDIEQMEREKLDKLAYVLTLNTEKEGIQEALEHEFADGTFSQKQVDELVQFRKANSSIFGKGWHNFSVKLMMELIPELYATSEEQMTILTRLGKQKTTSSSNKTKYIDEKRLTEEIYNPVVAKSVRQAIKIVNAAIKEYSDFDNIVIEMARETNEDDEKKAIQKIQKANKDEKDAAMLKAANQYNGKAELPHSVFHGHKQLATKIRLWHQQGERCLYTGKTISIHDLINNPNQFEIDHILPLSITFDDSLANKVLVYATANQEKGQRTPYQALDSMDDAWSFRELKAFVRESKTLSNKKKEYLLTEEDISKFDVRKKFIERNLVDTRYASRVVLNALQEHFRTRKIDTKVSVVRGQFTSQLRRHWGIDKIRDTYHHHAVDALIIAASSQLNLWKKQKNTLVSYSEDQLLDIETGELISDDEYKESVFKAPYQHFVDTLKSKDFEDSILFSYQVDSKFNRKISDATIYATRKAKLDKEKKEYTYTLGKIKDIYALGTKTPSKTGFYKFLDLYKKDKSQFLMYQKDRKTWDEVIEKILEQYRPFKEKDKNGKEVDFNPFEKYRIENGPIRKYSRKGNGPEIKSLKYYDNLLGRFVDITPSESKNPVALLSLNPWRTDVYYNTETRKYEFLGLKYADLCFEKGGSYGISKVKYNKIREKEGIGKNSEFKFTLYKNDLILIKDTETNRQQIFRFWSRTGKDNPKSFEKHKIELKPYEKARFEKGEELEVLGKVPPSSNQLQKNMQIENLSIYKVRTDVLGNQHIIKNEGDKPKLDF
>LS483366.1|SQF76254.1|1458742_1459678_+|putative-integrase-protein
MSYSHLTITDRIKIETYLDLGLKPCQIASKLSVHKSTISRELRRCQNGYSAVLAQEQYDHRAKQKGRKSRLTPKLKKEIEDGLKSSWSPEQICGRYQLEQKPMVAFKTIYNWLYAGLIDLDLSVLRRKGKTRQPKETRGTFRIGTSIAKRPKEVRNRETFGHWELDTVVSSRGKSKGCLATFLERKTRFYLAFKIPDRTAKSMFSAIEQLCKLFPKEALKTFTSDRGKEFACYPLVENLGIPFFFADAYSSWQRGGNENANGLLREYFPKKTDLAAISEEALTKALYDINHRPRKCLAYRTACEALEDEFE
>LS483366.1|SQF76255.1|1459764_1461426_-|sulfate-permease-family-protein
MDALKYITPKFFTTIKDYSKGQFIKDLVAGVIVAIIALPLSIALAIASGVNPEQGLYTAVVAGFFISFLGGSRVQIGGPTAAFVVIIYGIIAQYGMAGLTVATLMAGLMLIIMGLLRFGDLIKFIPKTITLGFTLGIAVGIVAGQIKDFLGLEMKSVPAEFLEKMIAYGKHLSSISWATLAIGILALLIQIFWPRLSKKIPGSLVAIFVTTAIVAFGHLPVKTIGDLYTIKAGLPSFTVPDLSFSLIRQMISPAFTIAILAAIESLLSCVVSDGMIGGNHRSNAELVGQGVGNIMSALFGGIPATGAIARTAANVKNGGRTPVAGMVHAFTLLLILLFLMPYASLIPMTCLASILMIVGYNMSGWRTVGRMIKRAPKSDVAVLLVTFVLTVFFDLVVAIEFGMVLAAFLFLKRMSDVAQIRQWVDKENLDDPVLSEDSDLKQVPKNTVVYEVFGALFFGAANNFLNVINDETKNVLILRMRNVPAMDISGLDALEETLAICQKRGMTLLLSHVNAQPYRVLEKSGFIQTIGADHICESTDQALEKAAALAKEA
>LS483366.1|SQF76256.1|1461673_1462288_-|Uncharacterised-protein
MWKWFKRLIVLVIVLFFAVAALLIPDKIDSQDQLKNVSTQTSLADLAQAGIGGASLSSGGVSTEINLDSNQFRQILKASMADSNDETLLNSTVELNDSYLTAKLPVSLGPIESTFSLDFTVSTNKEVILLDLAGAHLGRLPVPKSLVLPYLKKSIAQSSSGVRMVNNQIQLKLPEIGYEIEQATVTNSKMKVKLNIPISLPTSW
>LS483366.1|SQF76257.1|1462383_1463025_-|lipase/acylhydrolase-family-protein
MDELKEIKLKNYQYLNEVAIKGETLFTGSSLMELFPICEIARSRGVDDIIYNRGISGLNTDEFLQHIHPLLLDLQPSKVFINIGTNDMTEEPYGDQWFQHLTANIRQILEQTQAVLPHTKIYLMAFYPANLHLPWQTKASIQWMKLRTTENLDRCNQALEEIAQTYGCHFINCNAGLVNDRKEQKAEHTYDGVHLYANAYLKVYEALEPYLLN
>LS483366.1|SQF76258.1|1463051_1463663_-|CAAX-amino-protease-family-protein
MTLFISKLMNGIMELLIVSVIPFITWLIWSRKKVGFFDWIGLKKVESQQKRRLLLTILGISLLFLLFSIVVFSWFDSSQTATAAFSGKGIGALPAILAYAILGTALPEEIFFRGFLLKRLQGKLGFLGANLVQSLLFGLIHALMFIQLTGYLKAMAIMAFISLIAYVFGAINEKKAGGSILPSVFIHALANTVVGLLFAFSLV
>LS483366.1|SQF76259.1|1463766_1464129_-|Uncharacterised-protein
MAHLTPETRRKRRKAFCLIIEIICLVHFAIIVPRDRVFTPENWAHTPAPMRHKLMWSFHRQYQLEDMTREKVEKLLGKGNDLKGSVEYQLADDWIGGWRVYHIDYEQGRVIRAKETWQDW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448524	Streptococcus satellite phage Javan537, complete genome	984-1013	1	0.967
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448528	Streptococcus satellite phage Javan541, complete genome	984-1013	1	0.967
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448527	Streptococcus satellite phage Javan540, complete genome	984-1013	1	0.967
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	MK448979	Streptococcus phage Javan534, complete genome	8273-8301	1	0.966
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	MK448799	Streptococcus phage Javan535, complete genome	8273-8301	1	0.966
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	MK448800	Streptococcus phage Javan539, complete genome	8274-8302	1	0.966
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448601	Streptococcus satellite phage Javan653, complete genome	984-1013	2	0.933
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448577	Streptococcus satellite phage Javan614, complete genome	984-1013	3	0.9
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	MK448718	Streptococcus phage Javan253, complete genome	9175-9203	3	0.897
LS483366_3	3.5\|1452350\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452350-1452379	30	MK448980	Streptococcus phage Javan536, complete genome	9769-9798	3	0.9
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	MK448817	Streptococcus phage Javan59, complete genome	11534-11562	4	0.862
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448529	Streptococcus satellite phage Javan542, complete genome	963-992	5	0.833
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448362	Streptococcus satellite phage Javan209, complete genome	960-989	5	0.833
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448531	Streptococcus satellite phage Javan544, complete genome	963-992	5	0.833
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448361	Streptococcus satellite phage Javan208, complete genome	960-989	5	0.833
LS483366_3	3.3\|1452219\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452219-1452248	30	NZ_CP022300	Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence	2519-2548	6	0.8
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	NZ_CP046163	Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence	1139182-1139210	6	0.793
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	NZ_CP046066	Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence	1322574-1322602	6	0.793
LS483366_3	3.4\|1452285\|29\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452285-1452313	29	NZ_CP045356	Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence	437338-437366	6	0.793
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	AP013510	Uncultured Mediterranean phage uvMED DNA, complete genome, group G20, isolate: uvMED-CGR-C101A-MedDCM-OCT-S30-C6	3735-3764	7	0.767
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	AP013876	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C101A-MedDCM-OCT-S39-C9, * SEQUENCING IN PROGRESS *	12907-12936	7	0.767
LS483366_3	3.3\|1452219\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452219-1452248	30	NC_011246	Borrelia recurrentis A1 plasmid pl124, complete sequence	47296-47325	7	0.767
LS483366_3	3.3\|1452219\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452219-1452248	30	NC_011247	Borrelia duttonii Ly plasmid pl165, complete sequence	85484-85513	7	0.767
LS483366_3	3.8\|1452547\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452547-1452576	30	NZ_CP019718	Paenibacillus larvae subsp. larvae strain Eric_V plasmid unnamed1, complete sequence	2921-2950	7	0.767
LS483366_3	3.2\|1452153\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452153-1452182	30	MK448572	Streptococcus satellite phage Javan61, complete genome	963-992	8	0.733
LS483366_3	3.3\|1452219\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452219-1452248	30	MH319757	Marine virus AG-345-O18 Ga0172273_11 genomic sequence	62022-62051	8	0.733
LS483366_3	3.8\|1452547\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452547-1452576	30	MN693386	Marine virus AFVG_25M538, complete genome	18635-18664	8	0.733
LS483366_3	3.8\|1452547\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452547-1452576	30	MN693115	Marine virus AFVG_25M537, complete genome	23940-23969	8	0.733
LS483366_3	3.3\|1452219\|30\|LS483366\|CRISPRCasFinder,CRT,PILER-CR	1452219-1452248	30	MT349887	Acinetobacter phage 5W, complete genome	28291-28320	9	0.7

1. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448524 (Streptococcus satellite phage Javan537, complete genome) position: , mismatch: 1, identity: 0.967

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
agcgtgttgatccattagctttaaaatcaa	Protospacer
*************.****************

2. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448528 (Streptococcus satellite phage Javan541, complete genome) position: , mismatch: 1, identity: 0.967

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
agcgtgttgatccattagctttaaaatcaa	Protospacer
*************.****************

3. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448527 (Streptococcus satellite phage Javan540, complete genome) position: , mismatch: 1, identity: 0.967

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
agcgtgttgatccattagctttaaaatcaa	Protospacer
*************.****************

4. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448979 (Streptococcus phage Javan534, complete genome) position: , mismatch: 1, identity: 0.966

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
caacggtgctgtctgtgagcttgttttct	Protospacer
******************.**********

5. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448799 (Streptococcus phage Javan535, complete genome) position: , mismatch: 1, identity: 0.966

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
caacggtgctgtctgtgagcttgttttct	Protospacer
******************.**********

6. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448800 (Streptococcus phage Javan539, complete genome) position: , mismatch: 1, identity: 0.966

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
caacggtgctgtctgtgagcttgttttct	Protospacer
******************.**********

7. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448601 (Streptococcus satellite phage Javan653, complete genome) position: , mismatch: 2, identity: 0.933

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
aacgtgttgatccattagctttaaaatcaa	Protospacer
*.***********.****************

8. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448577 (Streptococcus satellite phage Javan614, complete genome) position: , mismatch: 3, identity: 0.9

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
aacgtgttgagccattagctttaaaatcaa	Protospacer
*.******** **.****************

9. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448718 (Streptococcus phage Javan253, complete genome) position: , mismatch: 3, identity: 0.897

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
cagtggtgctgtctgtgagcttgttttct	Protospacer
**..**************.**********

10. spacer 3.5|1452350|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448980 (Streptococcus phage Javan536, complete genome) position: , mismatch: 3, identity: 0.9

agacaattaagctaaattcagccccgccgt	CRISPR spacer
agacgattaagctaaattcagccccaccat	Protospacer
****.********************.**.*

11. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448817 (Streptococcus phage Javan59, complete genome) position: , mismatch: 4, identity: 0.862

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
tagtggtgctgtctgtgaactagttttct	Protospacer
.*..***************** *******

12. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448529 (Streptococcus satellite phage Javan542, complete genome) position: , mismatch: 5, identity: 0.833

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
tgactgtcgatccgttagttttaaaatcaa	Protospacer
 *  ***.**********.***********

13. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448362 (Streptococcus satellite phage Javan209, complete genome) position: , mismatch: 5, identity: 0.833

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
atactgttgctccgttagctttaaaagcaa	Protospacer
*   ***** **************** ***

14. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448531 (Streptococcus satellite phage Javan544, complete genome) position: , mismatch: 5, identity: 0.833

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
tgactgtcgatccgttagttttaaaatcaa	Protospacer
 *  ***.**********.***********

15. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448361 (Streptococcus satellite phage Javan208, complete genome) position: , mismatch: 5, identity: 0.833

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
atactgttgctccgttagctttaaaagcaa	Protospacer
*   ***** **************** ***

16. spacer 3.3|1452219|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022300 (Acinetobacter johnsonii strain IC001 plasmid pIC001B, complete sequence) position: , mismatch: 6, identity: 0.8

acatcatcaattctgtatcagcattaatgc	CRISPR spacer
acagatgccattctgtatcagcattgatgc	Protospacer
***    * ****************.****

17. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046163 (Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence) position: , mismatch: 6, identity: 0.793

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
catcggtgctgtctgtgaacttgacagca	Protospacer
** ******************** .  *

18. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046066 (Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence) position: , mismatch: 6, identity: 0.793

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
catcggtgctgtctgtgaacttgacagca	Protospacer
** ******************** .  *

19. spacer 3.4|1452285|29|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045356 (Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence) position: , mismatch: 6, identity: 0.793

caacggtgctgtctgtgaacttgttttct	CRISPR spacer
catcggtgctgtctgtgaacttgacagca	Protospacer
** ******************** .  *

20. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to AP013510 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G20, isolate: uvMED-CGR-C101A-MedDCM-OCT-S30-C6) position: , mismatch: 7, identity: 0.767

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
ctcttagtgatccgtcagctttagaatcaa	Protospacer
  * *. ********.*******.******

21. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to AP013876 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C101A-MedDCM-OCT-S39-C9, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
ctcttagtgatccgtcagctttagaatcaa	Protospacer
  * *. ********.*******.******

22. spacer 3.3|1452219|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NC_011246 (Borrelia recurrentis A1 plasmid pl124, complete sequence) position: , mismatch: 7, identity: 0.767

acatcatcaattctgtatcagcattaatgc	CRISPR spacer
aattcatcaatgctttatcagcattatacc	Protospacer
*  ******** ** ***********   *

23. spacer 3.3|1452219|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NC_011247 (Borrelia duttonii Ly plasmid pl165, complete sequence) position: , mismatch: 7, identity: 0.767

acatcatcaattctgtatcagcattaatgc	CRISPR spacer
aattcatcaatgctttatcagcattatacc	Protospacer
*  ******** ** ***********   *

24. spacer 3.8|1452547|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019718 (Paenibacillus larvae subsp. larvae strain Eric_V plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

acctcttgatgttgaaggaaaggtgaaaat	CRISPR spacer
acctctagatgatgaaggaaaggctagatc	Protospacer
****** **** ***********. *.* .

25. spacer 3.2|1452153|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MK448572 (Streptococcus satellite phage Javan61, complete genome) position: , mismatch: 8, identity: 0.733

agcgtgttgatccgttagctttaaaatcaa	CRISPR spacer
taaccgttgatccgttaagtttaaaatcta	Protospacer
 .  .************. ********* *

26. spacer 3.3|1452219|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MH319757 (Marine virus AG-345-O18 Ga0172273_11 genomic sequence) position: , mismatch: 8, identity: 0.733

acat-catcaattctgtatcagcattaatgc	CRISPR spacer
-tatgtatcaattctgtatcagcagtatcta	Protospacer
 .** .****************** ** .

27. spacer 3.8|1452547|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MN693386 (Marine virus AFVG_25M538, complete genome) position: , mismatch: 8, identity: 0.733

acctcttgatgttgaaggaaaggtgaaaat	CRISPR spacer
ccgtcttggtgttgaaggaaaggtcttagc	Protospacer
 * *****.***************   *..

28. spacer 3.8|1452547|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MN693115 (Marine virus AFVG_25M537, complete genome) position: , mismatch: 8, identity: 0.733

acctcttgatgttgaaggaaaggtgaaaat	CRISPR spacer
ccgtcttggtgttgaaggaaaggtcttagc	Protospacer
 * *****.***************   *..

29. spacer 3.3|1452219|30|LS483366|CRISPRCasFinder,CRT,PILER-CR matches to MT349887 (Acinetobacter phage 5W, complete genome) position: , mismatch: 9, identity: 0.7

acatcatcaattctgtatcagcattaatgc	CRISPR spacer
tagccatcaattcgctatcagcattaaatg	Protospacer
  ..*********  ************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

47170 : 94626

Staphylococcus_phage(16.67%)

protease,integrase,transposase,tRNA

attL 67928:67982|attR 74513:74567

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF74787.1\|47170_48862_-\|tRNA	arginyl-tRNA synthetase	A0A2I2L3K1	Orpheovirus	6.2e-77	32.9
SQF74790.1\|49019_49445_+	arginine repressor ArgR	NA	NA	NA	NA
SQF74795.1\|49444_49804_+	membrane protein	NA	NA	NA	NA
SQF74798.1\|49796_52355_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.2e-42	23.2
SQF74800.1\|52388_52844_-	integral membrane protein	NA	NA	NA	NA
SQF74803.1\|52840_53278_-	response regulator of the LytR/AlgR family protein	NA	NA	NA	NA
SQF74805.1\|53456_53762_+	Uncharacterised protein	NA	NA	NA	NA
SQF74808.1\|53811_55755_+	DNA mismatch repair protein MutL	A0A1B2LRQ5	Wolbachia_phage	1.9e-61	30.2
SQF74810.1\|55885_56107_+	Uncharacterised protein	NA	NA	NA	NA
SQF74814.1\|56264_56855_+	Holliday junction ATP-dependent DNA helicase RuvA	NA	NA	NA	NA
SQF74816.1\|56863_57418_+	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
SQF74819.1\|57514_58786_+	putative competence-damage inducible protein	NA	NA	NA	NA
SQF74821.1\|58821_59961_+	recombinase A	A0A0S2MVG1	Bacillus_phage	2.6e-119	61.5
SQF74823.1\|60091_61078_+\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	3.2e-57	40.4
SQF74826.1\|61215_61614_+	transcriptional regulator Spx	NA	NA	NA	NA
67928:67982	attL	NA	NA	NA	NA
SQF74830.1\|68065_69199_-\|integrase	site-specific recombinase, phage integrase family	A0A1B2AQ00	Phage_Wrath	1.4e-37	33.4
SQF74833.1\|69202_69397_-	hyptothetic protein	NA	NA	NA	NA
SQF74835.1\|69456_69843_-	Uncharacterised protein	NA	NA	NA	NA
SQF74837.1\|69845_71042_-	YdcR protein	NA	NA	NA	NA
SQF74838.1\|71082_71556_-	Uncharacterised protein	NA	NA	NA	NA
SQF74840.1\|71876_72329_+	Cro/CI family transcriptional regulator	A8ASM2	Listeria_phage	1.1e-12	33.8
SQF74843.1\|72495_73185_+	Uncharacterised protein	NA	NA	NA	NA
SQF74845.1\|73181_73994_+	Uncharacterised protein	NA	NA	NA	NA
SQF74847.1\|74030_74228_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
SQF74849.1\|74616_79011_+	DNA polymerase III subunit alpha	A0A0A7RWA3	Clostridium_phage	2.6e-18	35.3
74513:74567	attR	NA	NA	NA	NA
SQF74851.1\|79174_80416_+	aminopeptidase PepS	NA	NA	NA	NA
SQF74853.1\|80435_80666_+	integral membrane protein	NA	NA	NA	NA
SQF74856.1\|80798_81227_+	MarR family transcriptional regulator	NA	NA	NA	NA
SQF74858.1\|81314_81860_+	NADPH-dependent FMN reductase, putative	NA	NA	NA	NA
SQF74860.1\|81913_82900_-\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	4.2e-57	40.1
SQF74862.1\|83281_84814_-	Alkyl hydroperoxide reductase protein F	V9VEY6	Lactococcus_phage	2.4e-19	32.4
SQF74865.1\|84830_85391_-	peroxiredoxin	NA	NA	NA	NA
SQF74867.1\|85663_86431_+	30S ribosomal protein S2	NA	NA	NA	NA
SQF74870.1\|86541_87582_+	elongation factor Ts	NA	NA	NA	NA
SQF74872.1\|87688_88159_-	small multidrug export protein	NA	NA	NA	NA
SQF74874.1\|88476_88932_+	CtsR family transcriptional regulator	NA	NA	NA	NA
SQF74876.1\|88932_91383_+\|protease	ATP-dependent Clp protease, ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	1.0e-125	40.0
SQF74878.1\|91511_92768_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
SQF74881.1\|92986_93868_-\|transposase	ISSth1, transposase (orf2), IS3 family	A0A0C5AEA5	Paenibacillus_phage	3.6e-44	43.7
SQF74883.1\|93948_94626_-\|transposase	ISSth1, transposase (orf1), IS3 family	NA	NA	NA	NA

DBSCAN-SWA_2

343312 : 348788

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF75308.1\|343312_344077_+	branched-chain amino acid ABC transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	4.0e-15	25.2
SQF75309.1\|344076_344787_+	high-affinity branched-chain amino acid transport ATP-binding protein livF	A0A2H4PQG7	Staphylococcus_phage	8.2e-15	26.9
SQF75310.1\|344921_345581_+	AcuB family protein	M1NSC5	Streptococcus_phage	1.5e-66	59.2
SQF75311.1\|345759_346686_-	cysteine synthase	A0A1X9I5K7	Streptococcus_phage	9.4e-144	81.8
SQF75312.1\|346787_347414_-	Xaa-Pro dipeptidase	A0A1X9I5T8	Streptococcus_phage	1.5e-68	61.8
SQF75313.1\|347468_348788_+	late competence protein required for DNA uptake	A0A1X9I5S6	Streptococcus_phage	1.4e-121	52.1

DBSCAN-SWA_3

392152 : 431377

Lactobacillus_phage(13.33%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF75353.1\|392152_392527_+\|transposase	transposase	NA	NA	NA	NA
SQF75354.1\|392528_393371_+	DegV family protein	NA	NA	NA	NA
SQF75355.1\|393430_394198_+	dihydrodipicolinate reductase	NA	NA	NA	NA
SQF75356.1\|394194_395397_+\|tRNA	tRNA CCA-pyrophosphorylase	H7BUW3	unidentified_phage	3.6e-39	46.5
SQF75357.1\|395480_397361_+	ABC transporter domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.6e-65	32.1
SQF75358.1\|397439_397943_-	putative uncharacterized conserved protein	NA	NA	NA	NA
SQF75359.1\|398034_398796_-	mutT/nudix family protein	G3MA14	Bacillus_virus	4.0e-23	31.8
SQF75360.1\|398852_399959_-	transcriptional regulator	A0A2K9VDE3	Lactobacillus_phage	4.3e-79	43.8
SQF75361.1\|400316_401669_+	NAD(p)-specific glutamate dehydrogenase	NA	NA	NA	NA
SQF75362.1\|401847_403491_+	Uncharacterised protein	NA	NA	NA	NA
SQF75363.1\|403648_404059_+	polypeptide deformylase	A0A2I7S809	Vibrio_phage	9.3e-11	32.8
SQF75364.1\|404244_404688_+	MarR family transcriptional regulator	NA	NA	NA	NA
SQF75365.1\|404691_406506_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.7e-28	23.1
SQF75366.1\|406495_408274_+	ABC-type multidrug transport system, ATPase and permease component	W8CYL7	Bacillus_phage	5.4e-47	28.3
SQF75367.1\|408381_409005_+	GNAT family acetyltransferase	NA	NA	NA	NA
SQF75368.1\|409152_409776_+	GTP pyrophosphokinase	NA	NA	NA	NA
SQF75369.1\|409777_410455_+	Two-component response transcriptional regulator	NA	NA	NA	NA
SQF75370.1\|410468_411692_+	sensor histidine kinase	NA	NA	NA	NA
SQF75371.1\|411927_412665_+	UMP kinase	NA	NA	NA	NA
SQF75372.1\|412679_413237_+	ribosome recycling factor	NA	NA	NA	NA
SQF75373.1\|413326_414184_+	RNA-binding protein	NA	NA	NA	NA
SQF75374.1\|414192_414408_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQF75375.1\|414647_415850_+	surface immunogenic protein	A0A2P1N5D1	Gordonia_phage	3.4e-13	37.6
SQF75376.1\|415929_416994_+	phosphate starvation-induced protein	W8D063	Erwinia_phage	7.7e-49	48.2
SQF75377.1\|417118_417250_+	Uncharacterised protein	NA	NA	NA	NA
SQF75378.1\|417250_417817_+	Uncharacterised protein	NA	NA	NA	NA
SQF75379.1\|417969_419052_+	Uncharacterised protein	NA	NA	NA	NA
SQF75380.1\|419200_420061_+	Uncharacterised protein	NA	NA	NA	NA
SQF75381.1\|420170_422162_+\|tRNA	methionyl-tRNA synthetase (methionine--tRNA ligase) (MetRS)	A0A1V0SHR2	Klosneuvirus	7.5e-90	36.4
SQF75382.1\|422316_423804_-\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	3.0e-208	76.5
SQF75383.1\|423928_424774_-	2,5-diketo-d-gluconic acid reductase a	A0A2H4PQR8	Staphylococcus_phage	4.4e-47	37.8
SQF75384.1\|424784_425681_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.4e-06	34.6
SQF75385.1\|425920_426661_-\|protease	CAAX amino protease family protein	NA	NA	NA	NA
SQF75386.1\|427069_429028_+	glucan-binding protein C	NA	NA	NA	NA
SQF75387.1\|429256_430096_+	CHAP domain protein	NA	NA	NA	NA
SQF75388.1\|430401_430710_-\|transposase	transposase	A0A1X9I619	Streptococcus_phage	3.0e-14	90.9
SQF75389.1\|430733_431099_-\|transposase	transposase	A0A2I6AZV9	Macacine_betaherpesvirus	2.0e-20	52.3
SQF75390.1\|431098_431377_-\|transposase	IS3-Spn1, transposase	NA	NA	NA	NA

DBSCAN-SWA_4

650662 : 767581

Staphylococcus_phage(33.33%)

lysis,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF75551.1\|650662_651919_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.4e-129	58.3
SQF75552.1\|652061_653744_+	preprotein translocase subunit SecA	NA	NA	NA	NA
SQF75553.1\|653757_653937_+	Uncharacterised protein	NA	NA	NA	NA
SQF75554.1\|653940_654165_+	Uncharacterised protein	NA	NA	NA	NA
SQF75555.1\|656443_660874_-	Uncharacterised protein	NA	NA	NA	NA
SQF75556.1\|660895_661411_-	Uncharacterised protein	NA	NA	NA	NA
SQF75557.1\|666990_675507_-	Uncharacterised protein	NA	NA	NA	NA
SQF75558.1\|679145_683777_-	Uncharacterised protein	NA	NA	NA	NA
SQF75559.1\|683781_684180_+	LPXTG cell wall anchor domain	NA	NA	NA	NA
SQF75560.1\|684442_685063_-	RpiR family transcriptional regulator	NA	NA	NA	NA
SQF75561.1\|685502_689852_+	glucosyltransferase-S precursor (GTF-S) (Dextransucrase) (Sucrose 6-glucosyltransferase)	NA	NA	NA	NA
SQF75562.1\|690633_694617_+	MucBP domain protein	NA	NA	NA	NA
SQF75563.1\|694984_695701_+	lantibiotic transport ATP-binding protein srtF	A0A2H4PQG7	Staphylococcus_phage	1.1e-30	34.2
SQF75564.1\|695694_696504_+	ABC superfamily ATP binding cassette transporter permease subunit	NA	NA	NA	NA
SQF75565.1\|696484_697156_+	Uncharacterised protein	NA	NA	NA	NA
SQF75566.1\|697380_698055_+	response regulator	NA	NA	NA	NA
SQF75567.1\|698039_699107_+	NisK protein	NA	NA	NA	NA
SQF75568.1\|699212_699776_+	maltose O-acetyltransferase	NA	NA	NA	NA
SQF75569.1\|699898_700309_+	transcriptional regulator	NA	NA	NA	NA
SQF75570.1\|700334_700520_+	permease of the major facilitator family protein	NA	NA	NA	NA
SQF75571.1\|700559_701720_+	permease of the major facilitator family protein	A0A0M3UL24	Mycobacterium_phage	9.7e-05	24.6
SQF75572.1\|701886_702645_+\|protease	CAAX amino protease family protein	NA	NA	NA	NA
SQF75573.1\|702823_703840_+	Uncharacterised protein	NA	NA	NA	NA
SQF75574.1\|703949_706829_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75575.1\|707091_709332_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75576.1\|709613_711572_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75577.1\|711902_712775_+	pyridoxine biosynthesis protein	NA	NA	NA	NA
SQF75578.1\|712775_713369_+	glutamine amidotransferase subunit PdxT	NA	NA	NA	NA
SQF75579.1\|713534_714734_-	Uncharacterised protein	NA	NA	NA	NA
SQF75580.1\|715098_717528_-	glucosyltransferase-S	NA	NA	NA	NA
SQF75581.1\|717612_719136_-	glucan-binding protein A, GbpA	NA	NA	NA	NA
SQF75582.1\|719866_723562_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75583.1\|723616_727180_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75584.1\|727237_729709_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75585.1\|729766_732616_-	glucosyltransferase-I	NA	NA	NA	NA
SQF75586.1\|733626_738360_+	glucosyltransferase precursor	NA	NA	NA	NA
SQF75587.1\|738841_740827_+	glucosyltransferase-I	NA	NA	NA	NA
SQF75588.1\|740990_741230_-\|transposase	putative transposase	A0A146ICT8	Staphylococcus_phage	3.5e-10	45.9
SQF75589.1\|741174_742506_-\|transposase	transposase IS663-like	Q9MBP7	Staphylococcus_prophage	4.3e-65	34.6
SQF75590.1\|742791_743628_+	positive transcriptional regulator MutR family	NA	NA	NA	NA
SQF75591.1\|743734_743827_+	KxxxW-cyclized secreted peptide	NA	NA	NA	NA
SQF75592.1\|743896_745216_+	radical SAM	NA	NA	NA	NA
SQF75593.1\|745212_746304_+	putative transporter	NA	NA	NA	NA
SQF75594.1\|747215_751985_+	glucosyltransferase-I	NA	NA	NA	NA
SQF75595.1\|752215_752953_+	Predicted membrane protein	NA	NA	NA	NA
SQF75596.1\|752939_753215_+	transcriptional regulator	NA	NA	NA	NA
SQF75597.1\|753204_753792_+\|lysis	hemolysis inducing protein	NA	NA	NA	NA
SQF75598.1\|753839_754877_-	MccC family protein	NA	NA	NA	NA
SQF75599.1\|755386_755716_+	peptide methionine sulfoxide reductase	NA	NA	NA	NA
SQF75600.1\|755962_757978_+	metalloendopeptidase, putative	E3T4I7	Cafeteria_roenbergensis_virus	1.4e-72	29.2
SQF75601.1\|758114_758435_+	Uncharacterised protein	NA	NA	NA	NA
SQF75602.1\|758485_759319_+	serine/threonine protein phosphatase	NA	NA	NA	NA
SQF75603.1\|759421_760687_-	Uncharacterized conserved protein	NA	NA	NA	NA
SQF75604.1\|761012_762002_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
SQF75605.1\|762033_762609_+	dihydroxyacetone kinase subunit DhaL	NA	NA	NA	NA
SQF75606.1\|762612_762987_+	dihydroxyacetone kinase, phosphotransfer subunit	NA	NA	NA	NA
SQF75607.1\|763000_763984_+	igG binding protein	NA	NA	NA	NA
SQF75608.1\|764136_765228_+	glycerol dehydrogenase	NA	NA	NA	NA
SQF75609.1\|765530_765875_+	Uncharacterised protein	NA	NA	NA	NA
SQF75610.1\|766096_767581_-\|protease	ATP-dependent Zn protease	NA	NA	NA	NA

DBSCAN-SWA_5

845514 : 874230

Brazilian_cedratvirus(28.57%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF75675.1\|845514_846273_+\|bacteriocin	putative bacteriocin ABC transporter	G9BWD6	Planktothrix_phage	2.5e-25	36.2
SQF75676.1\|846274_848275_+	antimicrobial peptide ABC transporter permease	NA	NA	NA	NA
SQF75677.1\|848359_848854_+	Fe-S-cluster oxidoreductase	NA	NA	NA	NA
SQF75678.1\|848866_849532_+	Predicted membrane protein	NA	NA	NA	NA
SQF75679.1\|849670_850348_+	Predicted membrane protein (DUF2154)	NA	NA	NA	NA
SQF75680.1\|850414_851296_+	multidrug ABC transporter ATPase	A0A2R8FG22	Brazilian_cedratvirus	1.4e-16	29.9
SQF75681.1\|851292_852030_+	ABC transporter permease	NA	NA	NA	NA
SQF75682.1\|852040_852490_+	cytidine deaminase	NA	NA	NA	NA
SQF75683.1\|852632_853568_+	bile acid transporter	NA	NA	NA	NA
SQF75684.1\|854009_854219_+	Uncharacterised protein	NA	NA	NA	NA
SQF75685.1\|854229_854409_+	Uncharacterised protein	NA	NA	NA	NA
SQF75686.1\|854401_855283_+	multidrug ABC transporter ATPase	A0A2R8FG22	Brazilian_cedratvirus	6.4e-17	30.3
SQF75687.1\|855279_856017_+	multidrug ABC transporter permease	NA	NA	NA	NA
SQF75688.1\|856009_857104_+	sensor histidine kinase	NA	NA	NA	NA
SQF75689.1\|857100_857703_+	DNA-binding response regulator	NA	NA	NA	NA
SQF75690.1\|857867_859859_-	Reverse transcriptase (RNA-dependent DNA polymerase)	NA	NA	NA	NA
SQF75691.1\|860153_861419_+	rNA-directed DNA polymerase from retron EC86	A0A0H4U087	Erysipelothrix_phage	3.2e-09	23.7
SQF75692.1\|861460_862381_+	YjlA like protein	NA	NA	NA	NA
SQF75693.1\|862636_866548_+	fructan beta-fructosidase precursor (Exo-beta-D-fructosidase) (Fructanase)	NA	NA	NA	NA
SQF75694.1\|866630_867500_-	L-serine dehydratase, iron-sulfur-dependent subunit alpha	NA	NA	NA	NA
SQF75695.1\|867512_868184_-	L-serine dehydratase subunit beta	NA	NA	NA	NA
SQF75696.1\|868313_869333_-\|transposase	transposase	H7BUM7	unidentified_phage	2.3e-34	32.6
SQF75697.1\|869471_869846_-\|transposase	transposase	NA	NA	NA	NA
SQF75698.1\|869877_870357_-\|transposase	transposase	Q9JMN8	Wolbachia_phage	4.1e-10	28.9
SQF75699.1\|870415_870595_-\|transposase	transposase	NA	NA	NA	NA
SQF75700.1\|870869_872843_+	Lantibiotic biosynthesis protein	NA	NA	NA	NA
SQF75701.1\|872887_873271_+	Uncharacterised protein	NA	NA	NA	NA
SQF75702.1\|873243_874230_-\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	3.2e-57	40.4

DBSCAN-SWA_6

996397 : 1005669

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF75818.1\|996397_998206_+	glucosamine-fructose-6-phosphate aminotransferase	A7IW18	Paramecium_bursaria_Chlorella_virus	7.3e-100	39.1
SQF75819.1\|998323_998656_+	putative alkylphosphonate utilization operon protein PhnA	NA	NA	NA	NA
SQF75820.1\|998855_999497_+	ABC transporter permease	NA	NA	NA	NA
SQF75821.1\|999505_1000135_+	glutamine transport ATP-binding protein GlnQ	G3M9Y6	Bacillus_virus	3.8e-32	40.2
SQF75822.1\|1000147_1000999_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
SQF75823.1\|1001112_1002528_+	SOS responce UmuC protein	M1Q231	Streptococcus_phage	6.1e-195	70.7
SQF75824.1\|1002524_1002902_+	Uncharacterised protein	A0A1B0RXA8	Streptococcus_phage	1.2e-20	45.0
SQF75825.1\|1002879_1003161_+	Uncharacterised protein	M1PG86	Streptococcus_phage	3.0e-21	55.1
SQF75826.1\|1003296_1004316_+	alcohol dehydrogenase 1 (Alcohol dehydrogenase I) (ADH I)	A0A2K9L339	Tupanvirus	6.0e-27	25.5
SQF75827.1\|1004775_1005669_+	ABC transporter	A0A2H4PQG7	Staphylococcus_phage	2.4e-19	28.5

DBSCAN-SWA_7

1188454 : 1242049

Planktothrix_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF75989.1\|1188454_1189216_+\|transposase	transposase	Q9JMN8	Wolbachia_phage	1.2e-24	29.1
SQF75990.1\|1189235_1189622_+\|transposase	transposase	NA	NA	NA	NA
SQF75991.1\|1190420_1191005_-	uracil-DNA glycosylase	NA	NA	NA	NA
SQF75992.1\|1191045_1192452_-	dipeptidase PepV	NA	NA	NA	NA
SQF75993.1\|1192802_1192988_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
SQF75994.1\|1193059_1193581_-	membrane protein	NA	NA	NA	NA
SQF75995.1\|1193666_1194140_-	GNAT family acetyltransferase	NA	NA	NA	NA
SQF75996.1\|1194183_1194543_-	LSU ribosomal protein L20p	NA	NA	NA	NA
SQF75997.1\|1194599_1194800_-	50S ribosomal protein L35	NA	NA	NA	NA
SQF75998.1\|1194838_1195369_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.9e-12	36.0
SQF75999.1\|1195528_1196209_-	cytidylate kinase	NA	NA	NA	NA
SQF76000.1\|1196229_1196886_-	LysM domain-containing protein	NA	NA	NA	NA
SQF76001.1\|1197112_1197616_-	pore-forming peptide	NA	NA	NA	NA
SQF76002.1\|1197672_1198896_-	peptidase T	NA	NA	NA	NA
SQF76003.1\|1198969_1201096_-	cell wall hydrolase/autolysin	S5M633	Brevibacillus_phage	2.1e-21	40.5
SQF76004.1\|1201253_1201811_-	signal peptidase I	NA	NA	NA	NA
SQF76005.1\|1201932_1203162_-	TPR repeat containing protein	NA	NA	NA	NA
SQF76006.1\|1203151_1204330_-	transporter	NA	NA	NA	NA
SQF76007.1\|1204339_1204822_-	mutator MutT protein	NA	NA	NA	NA
SQF76008.1\|1204976_1205906_-	cell division ABC transporter permease	NA	NA	NA	NA
SQF76009.1\|1205898_1206591_-	cell division ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-30	36.6
SQF76010.1\|1206677_1207658_-	peptide chain release factor 2	NA	NA	NA	NA
SQF76011.1\|1207828_1208947_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
SQF76012.1\|1209058_1209898_+	Ser/Thr protein phosphatase family protein	NA	NA	NA	NA
SQF76013.1\|1209923_1210670_-	putative NADPH-dependent oxidoreductase	NA	NA	NA	NA
SQF76014.1\|1210779_1213464_-	P-type cation-transporting ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	6.2e-71	27.4
SQF76015.1\|1213728_1214115_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
SQF76016.1\|1214139_1214904_-	pnp/Udp family phosphorylase	NA	NA	NA	NA
SQF76017.1\|1214908_1215775_-	acetyltransferase, gnat family protein	NA	NA	NA	NA
SQF76018.1\|1215953_1216760_+	phosphatase yidA	NA	NA	NA	NA
SQF76019.1\|1216759_1217974_+	putative peptidoglycan FemAB like branched peptide synthesis protein	NA	NA	NA	NA
SQF76020.1\|1218112_1218586_-\|transposase	transposase-like protein	A0A1P8BMC0	Lactococcus_phage	2.0e-17	33.3
SQF76021.1\|1219272_1219632_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
SQF76022.1\|1219690_1220503_-	putative uncharacterized protein vicX	A0A0C5AJ83	Bacteriophage	2.1e-38	37.1
SQF76023.1\|1220508_1221849_-	sensor protein YycG	W8CYF6	Bacillus_phage	1.9e-36	35.3
SQF76024.1\|1221841_1222549_-	transcriptional regulator	W8CYM9	Bacillus_phage	1.9e-40	39.6
SQF76025.1\|1222834_1223602_+	glutamine transport ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	1.3e-37	42.0
SQF76026.1\|1223611_1224445_+	putative major cell-binding factor	NA	NA	NA	NA
SQF76027.1\|1224462_1225161_+	amino acid ABC transporter permease	NA	NA	NA	NA
SQF76028.1\|1225172_1225823_+	amino acid ABC transporter permease	NA	NA	NA	NA
SQF76029.1\|1226009_1226777_+	glutamine transport ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	4.8e-37	41.1
SQF76030.1\|1226788_1227622_+	polar amino acid ABC uptake transporter substrate binding protein	NA	NA	NA	NA
SQF76031.1\|1227639_1228338_+	amino acid ABC transporter permease	NA	NA	NA	NA
SQF76032.1\|1228349_1229000_+	amino acid ABC transporter permease	NA	NA	NA	NA
SQF76033.1\|1228919_1230512_-\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	6.0e-207	76.1
SQF76034.1\|1230640_1231522_-	DNA-entry nuclease	NA	NA	NA	NA
SQF76035.1\|1231583_1231772_-	competence-associated protein	NA	NA	NA	NA
SQF76036.1\|1231773_1233045_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
SQF76037.1\|1233112_1233283_-	membrane protein	NA	NA	NA	NA
SQF76038.1\|1233670_1234774_-	glycosyl hydrolase family 8	NA	NA	NA	NA
SQF76039.1\|1234782_1236093_-	N-acetyllactosaminide beta-1,6-N -acetylglucosaminyl-transferase	NA	NA	NA	NA
SQF76040.1\|1236085_1236226_-	Uncharacterised protein	NA	NA	NA	NA
SQF76041.1\|1236237_1237026_-	Uncharacterised protein	NA	NA	NA	NA
SQF76042.1\|1237028_1238180_-	UDP-N-acetylglucosamine 2-epimerase	A0A2P1ELS7	Moumouvirus	1.6e-31	29.0
SQF76043.1\|1239259_1239757_-\|transposase	transposase-like protein	A0A1X9I619	Streptococcus_phage	3.5e-36	91.4
SQF76044.1\|1241062_1242049_+\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	3.5e-56	39.8

DBSCAN-SWA_8

1259396 : 1279126

Streptococcus_phage(55.56%)

transposase,integrase

attL 1264937:1264952|attR 1273330:1273345

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76062.1\|1259396_1260155_-	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	7.7e-11	26.5
SQF76063.1\|1260151_1261021_-	ribose/xylose/arabinose/galactoside ABC transporter permease component	NA	NA	NA	NA
SQF76064.1\|1261030_1262032_-	ABC transporter substrate binding protein	NA	NA	NA	NA
SQF76065.1\|1262168_1262390_-	30S ribosomal protein S16	NA	NA	NA	NA
SQF76066.1\|1262500_1262710_+\|transposase	transposase of family protein	A0A1P8BMC0	Lactococcus_phage	1.3e-05	36.5
SQF76067.1\|1263026_1263356_-\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	3.2e-30	60.2
SQF76068.1\|1263327_1263831_-\|integrase	putative integrase protein	W5R8L2	Staphylococcus_phage	4.3e-26	50.4
SQF76069.1\|1264266_1264566_+\|transposase	transposase	A0A1X9I619	Streptococcus_phage	3.8e-46	89.9
1264937:1264952	attL	NA	NA	NA	NA
SQF76070.1\|1265160_1265583_-	putative phage-associated protein	C5IUL6	Streptococcus_phage	9.4e-59	80.0
SQF76071.1\|1265618_1266170_-	Uncharacterised protein	A0A2H4J7D7	uncultured_Caudovirales_phage	4.3e-96	91.3
SQF76072.1\|1266187_1266460_-	Uncharacterised protein	NA	NA	NA	NA
SQF76073.1\|1266479_1266824_-	Uncharacterised protein	A0A2I6QR21	Streptococcus_phage	2.7e-56	96.5
SQF76074.1\|1267274_1268021_-	phage-associated cell wall hydrolase	F8HGP2	Streptococcus_phage	1.8e-129	91.5
SQF76075.1\|1268022_1268319_-	lin2375 protein	A0A2H4J017	uncultured_Caudovirales_phage	1.7e-30	67.4
SQF76076.1\|1268399_1268588_-	phage protein	Q708Q8	Streptococcus_phage	2.8e-07	53.4
SQF76077.1\|1268755_1268959_+	Uncharacterised protein	M1PLB3	Streptococcus_phage	4.1e-20	79.1
SQF76078.1\|1268936_1269101_-	Uncharacterised protein	NA	NA	NA	NA
SQF76079.1\|1269119_1269356_-	prophage pi2 protein 05	A0A2P0VIW8	Streptococcus_phage	1.9e-24	78.3
SQF76080.1\|1269524_1269908_+	prophage LambdaSa03, transcriptional regulator,Cro/CI family	O34035	Streptococcus_phage	1.2e-31	56.7
SQF76081.1\|1269909_1270797_+	Abi family protein	NA	NA	NA	NA
SQF76082.1\|1270955_1271333_+	cI-like repressor, metallo-prtoeinase motif protein	W6LM52	Streptococcus_phage	7.9e-57	88.5
SQF76083.1\|1271326_1271965_+	Uncharacterised protein	A0A2H4J009	uncultured_Caudovirales_phage	3.4e-60	76.4
SQF76084.1\|1272099_1273272_+\|integrase	phage integrase family protein	A0A1S5S8R9	Streptococcus_phage	1.1e-101	52.0
SQF76085.1\|1273329_1274832_-	pyruvate kinase	NA	NA	NA	NA
1273330:1273345	attR	NA	NA	NA	NA
SQF76086.1\|1274902_1275922_-	6-phosphofructokinase	NA	NA	NA	NA
SQF76087.1\|1276015_1279126_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	2.0e-113	28.8

DBSCAN-SWA_9

1411714 : 1463663

Staphylococcus_phage(50.0%)

integrase,tRNA,transposase,protease

attL 1452000:1452035|attR 1459706:1459741

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76207.1\|1411714_1412614_-\|protease	protease HtpX-like protein	NA	NA	NA	NA
SQF76208.1\|1412615_1413176_-	cytoplasmic membrane protein	NA	NA	NA	NA
SQF76209.1\|1413324_1414329_-	deoxyribonuclease	NA	NA	NA	NA
SQF76210.1\|1414470_1417767_-	alpha-1,3-glucanase	NA	NA	NA	NA
SQF76211.1\|1417911_1418847_-\|integrase	putative integrase protein	W5R8L2	Staphylococcus_phage	4.0e-86	54.0
SQF76212.1\|1419358_1420246_-\|tRNA	glycyl-tRNA synthetase subunit alpha	NA	NA	NA	NA
SQF76213.1\|1420330_1421416_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
SQF76214.1\|1421408_1421747_-	plasmid maintenance system killer protein	NA	NA	NA	NA
SQF76215.1\|1421952_1423647_-	Uncharacterized conserved protein	NA	NA	NA	NA
SQF76216.1\|1423656_1423986_-	MazG-like family	NA	NA	NA	NA
SQF76217.1\|1424101_1424233_-	toxin-antitoxin system, antitoxin component, Xre family	NA	NA	NA	NA
SQF76218.1\|1424242_1425010_-	short chain dehydrogenase/reductase family oxidoreductase	NA	NA	NA	NA
SQF76219.1\|1425040_1426198_-	suB1079 undefined product 1051177:1052352 reverse MW:44904	NA	NA	NA	NA
SQF76220.1\|1426307_1426934_+	membrane protein	NA	NA	NA	NA
SQF76221.1\|1426971_1427298_-	HAD superfamily hydrolase	NA	NA	NA	NA
SQF76222.1\|1427336_1427813_-	HAD superfamily hydrolase	NA	NA	NA	NA
SQF76223.1\|1427901_1428354_+	Na+ driven multidrug efflux pump	NA	NA	NA	NA
SQF76224.1\|1428544_1429447_+	endolysin	A9QTG1	Bacillus_phage	3.6e-23	35.7
SQF76225.1\|1429559_1430033_+	transcriptional regulator	NA	NA	NA	NA
SQF76226.1\|1430035_1430674_+	phosphoglycerate mutase	NA	NA	NA	NA
SQF76227.1\|1430823_1431726_-	hydrolase	NA	NA	NA	NA
SQF76228.1\|1432045_1432525_-\|tRNA	Valyl-tRNA synthetase	NA	NA	NA	NA
SQF76229.1\|1432538_1433792_-	LysM domain-containing protein	NA	NA	NA	NA
SQF76230.1\|1434019_1435510_+\|tRNA	lysyl-tRNA synthetase	A0A2K9L3L6	Tupanvirus	2.3e-91	39.5
SQF76231.1\|1436118_1436997_+	sepS9	NA	NA	NA	NA
SQF76232.1\|1437295_1438630_+	manganese transport protein	NA	NA	NA	NA
SQF76233.1\|1438666_1438879_-\|tRNA	bacterial seryl-tRNA synthetase related protein	NA	NA	NA	NA
SQF76234.1\|1439003_1439288_+	Uncharacterised protein	NA	NA	NA	NA
SQF76235.1\|1439382_1439922_+	biotin synthase	NA	NA	NA	NA
SQF76236.1\|1440284_1441571_-	U32 family peptidase	Q6DW11	Phage_TP	1.2e-40	32.1
SQF76237.1\|1441666_1442596_-\|protease	protease	NA	NA	NA	NA
SQF76238.1\|1442834_1443131_+	membrane protein	NA	NA	NA	NA
SQF76239.1\|1443243_1444230_+\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	4.2e-57	40.1
SQF76240.1\|1444271_1444712_-	gas vesicle protein	NA	NA	NA	NA
SQF76241.1\|1444724_1445123_-	methyl-accepting chemotaxis-like domain-containing protein	NA	NA	NA	NA
SQF76242.1\|1445247_1446039_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
SQF76243.1\|1446038_1446968_-	HPr(Ser) kinase/phosphatase	NA	NA	NA	NA
SQF76244.1\|1447095_1447359_-	stress-responsive transcriptional regulator PspC	NA	NA	NA	NA
SQF76245.1\|1447424_1447865_-	SprT family metallopeptidase	NA	NA	NA	NA
SQF76246.1\|1447851_1449984_-	protein tex	NA	NA	NA	NA
SQF76247.1\|1450151_1450283_+	Uncharacterised protein	NA	NA	NA	NA
SQF76248.1\|1450288_1451191_+	putative permease	NA	NA	NA	NA
SQF76249.1\|1451190_1452006_+	membrane protein	NA	NA	NA	NA
1452000:1452035	attL	NA	NA	NA	NA
SQF76250.1\|1452675_1453728_-	CRISPR-associated protein Cas7	NA	NA	NA	NA
SQF76251.1\|1453724_1454048_-	CRISPR-associated endoribonuclease Cas2	NA	NA	NA	NA
SQF76252.1\|1454049_1454961_-	CRISPR-associated protein, Cas1 family	NA	NA	NA	NA
SQF76253.1\|1455137_1458557_-	CRISPR-associated endonuclease, Csn1 family	NA	NA	NA	NA
SQF76254.1\|1458742_1459678_+\|integrase	putative integrase protein	W5R8L2	Staphylococcus_phage	4.0e-86	54.0
SQF76255.1\|1459764_1461426_-	sulfate permease family protein	NA	NA	NA	NA
1459706:1459741	attR	NA	NA	NA	NA
SQF76256.1\|1461673_1462288_-	Uncharacterised protein	NA	NA	NA	NA
SQF76257.1\|1462383_1463025_-	lipase/acylhydrolase family protein	NA	NA	NA	NA
SQF76258.1\|1463051_1463663_-\|protease	CAAX amino protease family protein	NA	NA	NA	NA

DBSCAN-SWA_10

1513181 : 1522554

Streptococcus_phage(100.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76314.1\|1513181_1513859_-	3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	2.4e-112	91.6
SQF76315.1\|1513855_1515019_-	methyltransferase	W6LLI2	Streptococcus_phage	1.5e-210	94.3
SQF76316.1\|1515180_1517367_+	glycerol phosphate lipoteichoic acid synthase 2	W6LM83	Streptococcus_phage	0.0e+00	95.0
SQF76317.1\|1517370_1518840_-\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.8
SQF76318.1\|1519103_1519289_+\|tRNA	Isoleucyl-tRNA synthetase, putative	W6LMT3	Streptococcus_phage	1.9e-24	93.4
SQF76319.1\|1519442_1520747_-	Enolase	W6LP63	Streptococcus_phage	1.4e-246	99.5
SQF76320.1\|1520952_1521408_+	glycogen synthase	W6LLD2	Streptococcus_phage	5.0e-66	82.8
SQF76321.1\|1521438_1522554_-	glycerate kinase	W6LM47	Streptococcus_phage	1.9e-135	85.2

DBSCAN-SWA_11

1688674 : 1694976

Streptococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76477.1\|1688674_1689028_-	Spx/MgsR family transcriptional regulator	M1PLC0	Streptococcus_phage	1.3e-40	67.5
SQF76478.1\|1689062_1689557_-	methylated-DNA--protein-cysteine methyltransferase	M1PFU9	Streptococcus_phage	6.9e-37	46.3
SQF76479.1\|1689612_1690791_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	1.0e-179	80.1
SQF76480.1\|1690809_1691367_-	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	1.2e-56	60.1
SQF76481.1\|1691379_1692474_-	phosphoserine transaminase	M1Q1P2	Streptococcus_phage	2.8e-171	80.7
SQF76482.1\|1692628_1693522_-	transcriptional regulator	NA	NA	NA	NA
SQF76483.1\|1693637_1694033_+	lactoylglutathione lyase	NA	NA	NA	NA
SQF76484.1\|1694076_1694976_-	spfh domain/band 7 family protein	A0A1V0SL90	Klosneuvirus	1.8e-35	32.8

DBSCAN-SWA_12

1725912 : 1784126

Acinetobacter_phage(20.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76515.1\|1725912_1726854_-\|tRNA	tRNA-processing ribonuclease BN	NA	NA	NA	NA
SQF76516.1\|1726873_1727734_-	methionine aminopeptidase	NA	NA	NA	NA
SQF76517.1\|1727773_1729054_-	DRTGG domain-containing protein	NA	NA	NA	NA
SQF76518.1\|1729046_1729592_-	acetyltransferase	NA	NA	NA	NA
SQF76519.1\|1729657_1730920_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
SQF76520.1\|1731005_1733246_-	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.6e-56	60.9
SQF76521.1\|1733235_1733934_-	DNA uptake protein or related DNA-binding protein	NA	NA	NA	NA
SQF76522.1\|1734041_1734797_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
SQF76523.1\|1734890_1735862_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
SQF76524.1\|1735911_1736676_+	putative methyltransferase	NA	NA	NA	NA
SQF76525.1\|1736679_1736949_+	putative endonuclease containing a URI domain	A0A0C5AS36	Spodoptera_frugiperda_granulovirus	1.5e-06	39.5
SQF76526.1\|1737040_1737427_-\|transposase	transposase	NA	NA	NA	NA
SQF76527.1\|1737446_1738208_-\|transposase	transposase	Q9JMN8	Wolbachia_phage	9.4e-25	29.1
SQF76528.1\|1738479_1740066_-	ATP-dependent RNA helicase, dead/deah box family	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.4e-59	36.5
SQF76529.1\|1740260_1741166_-	cation transporter	NA	NA	NA	NA
SQF76530.1\|1741178_1741559_-	superfamily I DNA and RNA helicase	A6N235	Microbacterium_phage	1.0e-08	40.6
SQF76531.1\|1741863_1742439_+	putative proton-coupled thiamine transporter YuaJ	NA	NA	NA	NA
SQF76532.1\|1742607_1743471_+	transcriptional regulator MutR family protein	NA	NA	NA	NA
SQF76533.1\|1743583_1744762_+	macrolide-efflux protein	NA	NA	NA	NA
SQF76534.1\|1745063_1746608_-	regulator of gtfB	A0A1B0RXH7	Streptococcus_phage	5.4e-35	28.0
SQF76535.1\|1746955_1747621_-	membrane protein	NA	NA	NA	NA
SQF76536.1\|1747709_1749083_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
SQF76537.1\|1749195_1749921_+	ATP-dependent DNA helicase	NA	NA	NA	NA
SQF76538.1\|1749889_1750615_+	ATP-dependent DNA helicase	NA	NA	NA	NA
SQF76539.1\|1750586_1751288_+	ATP-dependent DNA helicase	NA	NA	NA	NA
SQF76540.1\|1751425_1752307_-\|transposase	ISSth1, transposase (orf2), IS3 family	A0A0C5AEA5	Paenibacillus_phage	3.6e-44	43.7
SQF76541.1\|1752387_1753065_-\|transposase	ISSth1, transposase (orf1), IS3 family	NA	NA	NA	NA
SQF76542.1\|1753186_1754041_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
SQF76543.1\|1754082_1754841_-	amino acid (glutamine) ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.1e-32	38.6
SQF76544.1\|1754842_1755520_-	amino acid (glutamine) ABC transporter permease	NA	NA	NA	NA
SQF76545.1\|1755479_1756160_-	amino acid ABC transporter permease	NA	NA	NA	NA
SQF76546.1\|1756597_1757644_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
SQF76547.1\|1757782_1757986_-	heavy metal-associated domain-containing protein	NA	NA	NA	NA
SQF76548.1\|1758061_1760290_-	copper-transporting P-type ATPase copA (Protein copA)	A0A218MNH6	uncultured_virus	1.6e-93	33.2
SQF76549.1\|1760293_1760725_-	putative transcriptional regulator	NA	NA	NA	NA
SQF76550.1\|1760892_1762065_-	major facilitator superfamily permease	NA	NA	NA	NA
SQF76551.1\|1762481_1762619_-	Uncharacterised protein	NA	NA	NA	NA
SQF76552.1\|1762780_1763563_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
SQF76553.1\|1763566_1764775_-	tryptophan synthase subunit beta	NA	NA	NA	NA
SQF76554.1\|1764771_1765353_-	N-(5'-phosphoribosyl)anthranilate isomerase	NA	NA	NA	NA
SQF76555.1\|1765339_1766107_-	indole-3-glycerol phosphate synthase	A0A0P0IR83	Acinetobacter_phage	6.3e-29	36.2
SQF76556.1\|1766103_1767108_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	2.5e-49	34.7
SQF76557.1\|1767197_1767764_-	para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II	A0A0P0IKJ1	Acinetobacter_phage	7.7e-40	45.6
SQF76558.1\|1767760_1769116_-	anthranilate synthase component I	NA	NA	NA	NA
SQF76559.1\|1769194_1769473_-	Chorismate mutase	NA	NA	NA	NA
SQF76560.1\|1770050_1770428_-	dihydroorotate dehydrogenase 1	NA	NA	NA	NA
SQF76561.1\|1770495_1772844_-	cation transporting ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	4.8e-35	24.9
SQF76562.1\|1773007_1773517_-	Uncharacterised protein	NA	NA	NA	NA
SQF76563.1\|1773818_1774118_+	YbaB/EbfC family DNA-binding protein	NA	NA	NA	NA
SQF76564.1\|1774228_1774846_-	Uncharacterised protein	NA	NA	NA	NA
SQF76565.1\|1775936_1776638_+	macrolide export ATP-binding/permease protein MacB	G9BWD6	Planktothrix_phage	2.0e-37	39.4
SQF76566.1\|1776652_1779295_+	ABC transporter permease	NA	NA	NA	NA
SQF76567.1\|1779345_1780074_-	MerR family transcriptional regulator	NA	NA	NA	NA
SQF76568.1\|1780248_1780839_-	DNA polymerase III subunit epsilon	NA	NA	NA	NA
SQF76569.1\|1780887_1781424_-	DNA-binding protein	NA	NA	NA	NA
SQF76570.1\|1781940_1782300_+	metal-sulfur cluster biosynthetic enzyme	NA	NA	NA	NA
SQF76571.1\|1782486_1783164_+\|transposase	ISSth1, transposase (orf1), IS3 family	NA	NA	NA	NA
SQF76572.1\|1783244_1784126_+\|transposase	ISSth1, transposase (orf2), IS3 family	A0A0C5AEA5	Paenibacillus_phage	3.6e-44	43.7

DBSCAN-SWA_13

1806629 : 1862188

Bacillus_virus(13.33%)

protease,bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76598.1\|1806629_1806932_-\|tRNA	aspartyl/glutamyl-tRNA amidotransferase subunit C	NA	NA	NA	NA
SQF76599.1\|1807071_1807416_-	group 1 glycosyl transferase	NA	NA	NA	NA
SQF76600.1\|1807532_1808972_-	glycoside hydrolase family 1	NA	NA	NA	NA
SQF76601.1\|1809128_1809680_-	isochorismatase family protein	G3MA16	Bacillus_virus	3.4e-24	40.3
SQF76602.1\|1809746_1810532_-	GTP-sensing transcriptional pleiotropic repressor CodY	NA	NA	NA	NA
SQF76603.1\|1810798_1812013_-	class I and II aminotransferase	NA	NA	NA	NA
SQF76604.1\|1812372_1812825_+	universal stress family protein	NA	NA	NA	NA
SQF76605.1\|1812906_1813659_-	membrane associated protein	NA	NA	NA	NA
SQF76606.1\|1813728_1814529_-	pyruvate formate-lyase activating enzyme	A0A2P0VNQ0	Tetraselmis_virus	2.9e-24	31.8
SQF76607.1\|1814715_1815438_-	cell surface protein A	NA	NA	NA	NA
SQF76608.1\|1815791_1817123_-	magnesium and cobalt efflux protein CorC	NA	NA	NA	NA
SQF76609.1\|1817233_1818016_+	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	A0A2K9L0W2	Tupanvirus	1.7e-08	25.6
SQF76610.1\|1818199_1820266_-	Na+/H+ antiporter	NA	NA	NA	NA
SQF76611.1\|1820274_1820517_-	Uncharacterised protein	NA	NA	NA	NA
SQF76612.1\|1820513_1821062_-	putative rRNA methylase	A0A2H4PQV0	Staphylococcus_phage	2.4e-38	44.6
SQF76613.1\|1821058_1822003_-	radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.2e-34	46.2
SQF76614.1\|1822086_1823163_-\|protease	ATP-dependent protease La	NA	NA	NA	NA
SQF76615.1\|1823140_1823638_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.2e-14	30.1
SQF76616.1\|1823670_1824273_-	methyltransferase	NA	NA	NA	NA
SQF76617.1\|1824358_1825279_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.7e-87	52.3
SQF76618.1\|1825344_1825569_-	thioredoxin	NA	NA	NA	NA
SQF76619.1\|1825780_1826524_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-29	40.1
SQF76620.1\|1826523_1827447_-	polar amino acid ABC uptake transporter membrane-spanning protein	NA	NA	NA	NA
SQF76621.1\|1827683_1827998_+	Uncharacterised protein	NA	NA	NA	NA
SQF76622.1\|1827866_1828697_-	polar amino acid ABC uptake transporter substrate binding protein	NA	NA	NA	NA
SQF76623.1\|1828911_1829802_-	protein, beta-lactamase/transpeptidase-like predicted	NA	NA	NA	NA
SQF76624.1\|1829902_1831012_-	DNA polymerase IV (Pol IV)	NA	NA	NA	NA
SQF76625.1\|1831279_1833592_+	pyruvate formate-lyase	A0A2P0VNR5	Tetraselmis_virus	1.1e-113	32.4
SQF76626.1\|1833750_1833888_+	Uncharacterised protein	NA	NA	NA	NA
SQF76627.1\|1833902_1835597_+	extracellular protein	NA	NA	NA	NA
SQF76628.1\|1835884_1836667_+	carbonic anhydrase	NA	NA	NA	NA
SQF76629.1\|1836752_1837205_+	acetyltransferase	NA	NA	NA	NA
SQF76630.1\|1837221_1837896_-	putative lipoprotein	NA	NA	NA	NA
SQF76631.1\|1837879_1838827_-	beta-lactamase	A0A1D8EXR7	Mycobacterium_phage	1.2e-05	25.1
SQF76632.1\|1838826_1839582_-	C3-degrading proteinase	NA	NA	NA	NA
SQF76633.1\|1839755_1840427_+	abortive infection protein	NA	NA	NA	NA
SQF76634.1\|1840514_1841381_-	glycerol facilitator-aquaporin gla	M1HJ77	Paramecium_bursaria_Chlorella_virus	2.6e-18	28.4
SQF76635.1\|1841504_1843772_+	Xaa-pro dipeptidyl-peptidase	NA	NA	NA	NA
SQF76636.1\|1843852_1844233_-\|bacteriocin	putative bacteriocin self-immunity protein	NA	NA	NA	NA
SQF76637.1\|1844357_1844648_-	membrane protein	NA	NA	NA	NA
SQF76638.1\|1844939_1845236_-	Xre-like reg	NA	NA	NA	NA
SQF76639.1\|1845274_1845481_-	Uncharacterised protein	NA	NA	NA	NA
SQF76640.1\|1846170_1847796_-\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	1.5e-208	76.8
SQF76641.1\|1848103_1848505_-	Uncharacterised protein	NA	NA	NA	NA
SQF76642.1\|1848787_1848976_-\|bacteriocin	bacteriocin BlpI	NA	NA	NA	NA
SQF76643.1\|1848988_1849222_-	Bacteriocin-like peptide J BlpJ	NA	NA	NA	NA
SQF76644.1\|1849365_1849533_-	membrane protein	NA	NA	NA	NA
SQF76645.1\|1849548_1849728_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
SQF76646.1\|1849887_1851633_-	multidrug resistance-like ATP-binding protein mdlB	F2Y1V6	Organic_Lake_phycodnavirus	3.3e-17	26.8
SQF76647.1\|1851625_1853383_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.0e-45	28.2
SQF76648.1\|1853446_1853842_-	Uncharacterised protein	NA	NA	NA	NA
SQF76649.1\|1853828_1853918_-	Uncharacterised protein	NA	NA	NA	NA
SQF76650.1\|1853995_1854523_-	VanZ-like protein	NA	NA	NA	NA
SQF76651.1\|1854524_1855694_-	radical SAM enzyme, Cfr family	NA	NA	NA	NA
SQF76652.1\|1855697_1856420_-	transcriptional regulator	NA	NA	NA	NA
SQF76653.1\|1856474_1857830_-	Ser/Thr phosphatase family protein	NA	NA	NA	NA
SQF76654.1\|1858112_1858349_-	Bacteriocin class II with double-glycine leader peptide	NA	NA	NA	NA
SQF76655.1\|1858489_1859743_-	two-component sensor histidine kinase	NA	NA	NA	NA
SQF76656.1\|1859739_1860468_-	response regulator	NA	NA	NA	NA
SQF76657.1\|1861168_1862188_+\|transposase	transposase	A0A2K9V2S9	Faecalibacterium_phage	7.1e-36	34.9

DBSCAN-SWA_14

1979161 : 2031957

Streptococcus_phage(33.33%)

protease,bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76773.1\|1979161_1980622_+\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	3.6e-206	76.1
SQF76774.1\|1980634_1981048_-	esterase	NA	NA	NA	NA
SQF76775.1\|1981065_1981401_-	thioredoxin domain containing protein	NA	NA	NA	NA
SQF76776.1\|1986925_1988068_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	9.3e-85	42.8
SQF76777.1\|1988274_1988409_-	LSU ribosomal protein L34p	NA	NA	NA	NA
SQF76778.1\|1988604_1989168_-	Flavodoxin-like fold protein	NA	NA	NA	NA
SQF76779.1\|1989164_1989761_-	putative transcriptional regulator	NA	NA	NA	NA
SQF76780.1\|1989892_1990936_-	r3H domain protein	NA	NA	NA	NA
SQF76781.1\|1990947_1991802_-	preprotein translocase subunit YidC	NA	NA	NA	NA
SQF76782.1\|1991869_1992205_-	ribonuclease P protein component	NA	NA	NA	NA
SQF76783.1\|1992289_1993675_-	argininosuccinate lyase	NA	NA	NA	NA
SQF76784.1\|1994001_1995201_-	argininosuccinate synthase	NA	NA	NA	NA
SQF76785.1\|1996192_1997014_-\|transposase	transposase InsI for insertion sequence element IS30B/C/D	W5R8L2	Staphylococcus_phage	2.8e-43	41.1
SQF76786.1\|1997225_1997969_-	response regulator FasA	NA	NA	NA	NA
SQF76787.1\|1997970_1999287_-	putative histidine kinase	NA	NA	NA	NA
SQF76788.1\|1999310_2000591_-	sensor histidine kinase	NA	NA	NA	NA
SQF76789.1\|2000612_2001503_-	putative histidine kinase of the competence regulon, ComD	NA	NA	NA	NA
SQF76790.1\|2001557_2002865_-	putative histidine kinase of the competence regulon, ComD	NA	NA	NA	NA
SQF76791.1\|2003317_2004772_-\|tRNA	glutamyl-tRNA synthetase	NA	NA	NA	NA
SQF76792.1\|2005007_2006978_-	oligopeptide binding protein 3	NA	NA	NA	NA
SQF76793.1\|2007159_2007849_-	50S ribosomal protein L1	NA	NA	NA	NA
SQF76794.1\|2007948_2008374_-	50S ribosomal protein L11	NA	NA	NA	NA
SQF76795.1\|2008545_2008899_+	integral membrane protein	NA	NA	NA	NA
SQF76796.1\|2008993_2009491_-	carbonate dehydratase	NA	NA	NA	NA
SQF76797.1\|2009641_2010337_-	HTH DNA-binding protein	NA	NA	NA	NA
SQF76798.1\|2010413_2011661_-	DNA repair protein	NA	NA	NA	NA
SQF76799.1\|2011771_2012239_-	Isochorismatase family	NA	NA	NA	NA
SQF76800.1\|2012248_2012695_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	Q332E8	Clostridium_botulinum_C_phage	2.5e-33	50.7
SQF76801.1\|2012902_2013505_+	NADPH-dependent fmn reductase	A0A2P0ZL77	Lactobacillus_phage	1.8e-55	54.2
SQF76802.1\|2013523_2014774_+	flavin reductase	A0A2P0ZL82	Lactobacillus_phage	7.6e-56	52.7
SQF76803.1\|2014890_2015682_+	formate/nitrite transporter family protein	NA	NA	NA	NA
SQF76804.1\|2015690_2016257_+	membrane-bound protein	NA	NA	NA	NA
SQF76805.1\|2016371_2017394_+	glycerol-3-phosphate dehydrogenase [NAD(P)+]	NA	NA	NA	NA
SQF76806.1\|2017410_2018325_+	UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose pyrophosphorylase) (UDPGP) (Alpha-D-glucosyl-1-phosphate uridylyltransferase) (Uridine diphosphoglucose pyrophosphorylase)	A0A127AW70	Bacillus_phage	2.8e-76	51.9
SQF76807.1\|2018370_2019045_-	peptidase, S54 family	NA	NA	NA	NA
SQF76808.1\|2019035_2019563_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
SQF76809.1\|2019631_2020765_-	aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase	NA	NA	NA	NA
SQF76810.1\|2020842_2021541_-	2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase	NA	NA	NA	NA
SQF76811.1\|2021626_2022379_-	haloacid dehalogenase-like hydrolase	NA	NA	NA	NA
SQF76812.1\|2022492_2023332_-	methyltransferase domain protein	NA	NA	NA	NA
SQF76813.1\|2023752_2023911_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
SQF76814.1\|2023930_2024098_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
SQF76815.1\|2024145_2024400_+	Uncharacterised protein	NA	NA	NA	NA
SQF76816.1\|2024485_2025004_-\|tRNA	tRNA-specific adenosine deaminase	NA	NA	NA	NA
SQF76817.1\|2025773_2026166_-	single-strand binding protein	A1EAD1	Streptococcus_phage	7.5e-26	47.0
SQF76818.1\|2026593_2027271_-\|protease	CAAX amino protease family protein	NA	NA	NA	NA
SQF76819.1\|2027536_2028160_-	emap domain protein	NA	NA	NA	NA
SQF76820.1\|2028191_2028716_-	Uncharacterised protein	NA	NA	NA	NA
SQF76821.1\|2028719_2029034_-	thioredoxin	NA	NA	NA	NA
SQF76822.1\|2029030_2029315_-	membrane protein	NA	NA	NA	NA
SQF76823.1\|2029414_2030482_+	glutamyl aminopeptidase	NA	NA	NA	NA
SQF76824.1\|2030497_2031268_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	5.6e-33	36.1
SQF76825.1\|2031294_2031957_-\|protease	CAAX amino protease family protein	NA	NA	NA	NA

DBSCAN-SWA_15

2162266 : 2173700

Staphylococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQF76966.1\|2162266_2162965_-	immunodominant antigen A precursor	Q4Z8Z7	Staphylococcus_phage	2.1e-26	68.8
SQF76967.1\|2163148_2163730_-	LysM domain-containing protein	A0A249XZV3	Enterococcus_phage	4.6e-24	54.1
SQF76968.1\|2164030_2164825_-	cobalt ABC transporter permease CbiQ-like protein	NA	NA	NA	NA
SQF76969.1\|2164817_2165660_-	cobalt import ATP-binding protein CbiO 1	A0A2H4PQG7	Staphylococcus_phage	1.8e-13	27.9
SQF76970.1\|2165635_2166466_-	cobalt import ATP-binding protein CbiO 2	G9BWD6	Planktothrix_phage	1.8e-21	32.7
SQF76971.1\|2166478_2167021_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
SQF76972.1\|2167033_2167891_-	XRE-family DNA-binding domain-containing protein	NA	NA	NA	NA
SQF76973.1\|2167949_2169227_-	peptidase	A0A2H4UVM3	Bodo_saltans_virus	1.3e-05	28.7
SQF76974.1\|2169228_2170479_-	peptidase M16 inactive domain protein	A0A1X9I714	Streptococcus_phage	2.5e-91	39.9
SQF76975.1\|2170556_2170934_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	2.0e-23	71.1
SQF76976.1\|2170936_2172037_+	DNA replication and repair protein RecF	NA	NA	NA	NA
SQF76977.1\|2172218_2173700_-	inositol-5-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.6e-95	40.3

Anti-CRISPR protein detection

Acr_ID: LS483366.1|SQF76071.1|1265618_1266170_-|Uncharacterised-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LS483366.1|SQF76071.1|1265618_1266170_-|Uncharacterised-protein

1265618_1266170_-

183 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|42	0.825136612021858	1	1.0

1259396-1279126

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LS483366

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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