CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483399	Streptococcus pyogenes strain NCTC8227 genome assembly, chromosome: 1	1 crisprs	DinG,csm6,cas3,DEDDh,csa3	0	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483399_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483399_1

749792-749881

Orphan

II-A

Consensus_repeat	Method
GCTATGCTGTTTTGAATGGTCCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483399_1

>merge|LS483399|1|749792-749881|CRISPRCasFinder
GCTATGCTGTTTTGAATGGTCCCAAAACCTCTTATGTTTTAAGACACCACTTTGGATAGTTTTAGAGCTATGCTGTTTTGAATGGTCTCC

>LS483399|1|1|749792-749881|CRISPRCasFinder
GCTATGCTGTTTTGAATGGTCCCA	AAACCTCTTATGTTTTAAGACACCACTTTGGATAGTTTTAGA
GCTATGCTGTTTTGAATGGTCTCC

Protein	Signature genes	Signature genes Name	Protein_function
LS483399.1\|SQG51954.1\|755875_756301_+\|PTS-system-mannose-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
LS483399.1\|SQG51959.1\|756833_757643_+\|PTS-system,-mannose-specific-IIC-component	unknown	unknown	gnl\|CDD\|226238
LS483399.1\|SQG51924.1\|740855_742193_-\|UDP-N-acetylmuramoylalanyl-D-glutamate-2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|223840
LS483399.1\|SQG51936.1\|746275_747472_+\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
LS483399.1\|SQG51961.1\|757639_758467_+\|phospotransferase-system-(PTS),-enzyme-II-component-D	unknown	unknown	gnl\|CDD\|226239
LS483399.1\|SQG51944.1\|749997_750195_+\|nucleoside-diphosphate-kinase-protein-Ndk	unknown	unknown	gnl\|CDD\|179085
LS483399.1\|SQG51948.1\|752685_753900_+\|collagen-like-surface-protein	unknown	unknown	gnl\|CDD\|223003
LS483399.1\|SQG51934.1\|745637_746279_+\|acetyltransferase-GNAT-Family	unknown	unknown	unknown
LS483399.1\|SQG51952.1\|754652_755669_+\|hypothetical-membrane-spanning-protein	unknown	unknown	gnl\|CDD\|225411
LS483399.1\|SQG51942.1\|748997_749630_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226884
LS483399.1\|SQG51963.1\|758602_760252_+\|two-component-sensor-kinase	unknown	unknown	gnl\|CDD\|225519
LS483399.1\|SQG51946.1\|750528_752361_+\|GTP-binding-protein-LepA	unknown	unknown	gnl\|CDD\|235462
LS483399.1\|SQG51940.1\|748233_748998_+\|haloacid-dehalogenase-like-hydrolase	unknown	unknown	gnl\|CDD\|319832
LS483399.1\|SQG51922.1\|740064_740856_-\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|225974
LS483399.1\|SQG51938.1\|747481_748234_+\|oleoyl-[acyl-carrier-protein]-hydrolase	unknown	unknown	gnl\|CDD\|226401
LS483399.1\|SQG51929.1\|743148_744105_+\|hypothetical-membrane-associated-protein	unknown	unknown	gnl\|CDD\|227193
LS483399.1\|SQG51926.1\|742300_743152_+\|disA-bacterial-checkpoint-controller-nucleotide-binding-family-protein	unknown	unknown	gnl\|CDD\|224539
LS483399.1\|SQG51950.1\|754085_754523_+\|methionine-sulfoxide-reductase-B	unknown	unknown	gnl\|CDD\|234692
LS483399.1\|SQG51931.1\|744158_745514_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
LS483399.1\|SQG51957.1\|756325_756817_+\|PTS-system-mannose/fructose-family-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976

Protein	Function_ID	Function_description	E-value
LS483399.1\|SQG51954.1\|755875_756301_+\|PTS-system-mannose-specific-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	1.6728e-30
LS483399.1\|SQG51959.1\|756833_757643_+\|PTS-system,-mannose-specific-IIC-component	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	2.10148e-76
LS483399.1\|SQG51924.1\|740855_742193_-\|UDP-N-acetylmuramoylalanyl-D-glutamate-2,-6-diaminopimelate-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.36017e-110
LS483399.1\|SQG51936.1\|746275_747472_+\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
LS483399.1\|SQG51961.1\|757639_758467_+\|phospotransferase-system-(PTS),-enzyme-II-component-D	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
LS483399.1\|SQG51944.1\|749997_750195_+\|nucleoside-diphosphate-kinase-protein-Ndk	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	1.34932e-09
LS483399.1\|SQG51948.1\|752685_753900_+\|collagen-like-surface-protein	gnl\|CDD\|223003	PHA03169, PHA03169, hypothetical protein; Provisional.	4.26603e-08
LS483399.1\|SQG51952.1\|754652_755669_+\|hypothetical-membrane-spanning-protein	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	5.20392e-102
LS483399.1\|SQG51942.1\|748997_749630_+\|membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.04206e-87
LS483399.1\|SQG51963.1\|758602_760252_+\|two-component-sensor-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	3.92596e-77
LS483399.1\|SQG51946.1\|750528_752361_+\|GTP-binding-protein-LepA	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
LS483399.1\|SQG51940.1\|748233_748998_+\|haloacid-dehalogenase-like-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.84001e-127
LS483399.1\|SQG51922.1\|740064_740856_-\|cobyric-acid-synthase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.00186e-142
LS483399.1\|SQG51938.1\|747481_748234_+\|oleoyl-[acyl-carrier-protein]-hydrolase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	1.17846e-104
LS483399.1\|SQG51929.1\|743148_744105_+\|hypothetical-membrane-associated-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	3.12847e-114
LS483399.1\|SQG51926.1\|742300_743152_+\|disA-bacterial-checkpoint-controller-nucleotide-binding-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.09715e-101
LS483399.1\|SQG51950.1\|754085_754523_+\|methionine-sulfoxide-reductase-B	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	4.01251e-83
LS483399.1\|SQG51931.1\|744158_745514_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
LS483399.1\|SQG51957.1\|756325_756817_+\|PTS-system-mannose/fructose-family-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55

>LS483399.1|SQG51942.1|748997_749630_+|membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>LS483399.1|SQG51940.1|748233_748998_+|haloacid-dehalogenase-like-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLTNQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYETLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>LS483399.1|SQG51938.1|747481_748234_+|oleoyl-[acyl-carrier-protein]-hydrolase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGDLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLYRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKITLKYVKEVSPGGQITSSYHLDQLTSYHQIISDGQLNAQAMIEWRAIKPIESETD
>LS483399.1|SQG51936.1|746275_747472_+|coproporphyrinogen-III-oxidase
MKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFESYDIHDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>LS483399.1|SQG51934.1|745637_746279_+|acetyltransferase-GNAT-Family
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDIQKRRIKQLTKNFERLLDTSSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLTDMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>LS483399.1|SQG51931.1|744158_745514_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>LS483399.1|SQG51929.1|743148_744105_+|hypothetical-membrane-associated-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>LS483399.1|SQG51926.1|742300_743152_+|disA-bacterial-checkpoint-controller-nucleotide-binding-family-protein
MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALTGTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEKFGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPLNADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAIGLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVTLPWYKKILGGKSK
>LS483399.1|SQG51924.1|740855_742193_-|UDP-N-acetylmuramoylalanyl-D-glutamate-2,-6-diaminopimelate-ligase
MKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDLSKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>LS483399.1|SQG51922.1|740064_740856_-|cobyric-acid-synthase
MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVAEKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV
>LS483399.1|SQG51944.1|749997_750195_+|nucleoside-diphosphate-kinase-protein-Ndk
MEQTFFMIKPDGVKQGEVVGEVLRWIERLRLTFKRFELRQASSKYLAKHDEALVINLLILNLKLT
>LS483399.1|SQG51946.1|750528_752361_+|GTP-binding-protein-LepA
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>LS483399.1|SQG51948.1|752685_753900_+|collagen-like-surface-protein
MRADDQQEERAQARTELIQELAQGLGRLKEKTIPTRGNLDNNAYMAELLKYLQERGQVEDGWRTSLLQGMQRHVFDGLDGRNGEKGESGDRGPTGPTGPRGERGLQGPAGEAGPRGERGLQGPAGEQGLRGETGPQGPAGKDGEVGPRGDRGETGPAGPVGPRGERGEAGPAGKDGERGPVGPAGKDGQDGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMMTAGVVAVAKRQENN
>LS483399.1|SQG51950.1|754085_754523_+|methionine-sulfoxide-reductase-B
METSEELKQRIGDLSYEVTQHAATESPFTGEYDIFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>LS483399.1|SQG51952.1|754652_755669_+|hypothetical-membrane-spanning-protein
MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLLALFYEHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGLQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>LS483399.1|SQG51954.1|755875_756301_+|PTS-system-mannose-specific-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLAALLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>LS483399.1|SQG51957.1|756325_756817_+|PTS-system-mannose/fructose-family-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>LS483399.1|SQG51959.1|756833_757643_+|PTS-system,-mannose-specific-IIC-component
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAINKQTTFDSKESEEEDFFA
>LS483399.1|SQG51961.1|757639_758467_+|phospotransferase-system-(PTS),-enzyme-II-component-D
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>LS483399.1|SQG51963.1|758602_760252_+|two-component-sensor-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPNQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448771	Streptococcus phage Javan481, complete genome	8135-8176	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448862	Streptococcus phage Javan178, complete genome	8111-8152	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448775	Streptococcus phage Javan489, complete genome	12024-12065	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448969	Streptococcus phage Javan514, complete genome	11006-11047	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448681	Streptococcus phage Javan141, complete genome	7911-7952	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448794	Streptococcus phage Javan525, complete genome	10219-10260	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448972	Streptococcus phage Javan520, complete genome	8060-8101	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448763	Streptococcus phage Javan451, complete genome	9253-9294	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448774	Streptococcus phage Javan487, complete genome	8120-8161	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448773	Streptococcus phage Javan485, complete genome	11006-11047	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448958	Streptococcus phage Javan486, complete genome	10360-10401	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448777	Streptococcus phage Javan491, complete genome	8351-8392	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448765	Streptococcus phage Javan459, complete genome	10219-10260	10	0.762
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448675	Streptococcus phage Javan129, complete genome	12189-12230	11	0.738
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448944	Streptococcus phage Javan452, complete genome	12399-12440	11	0.738
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448672	Streptococcus phage Javan117, complete genome	7980-8021	11	0.738
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448849	Streptococcus phage Javan128, complete genome	7884-7925	11	0.738
LS483399_1	1.1\|749816\|42\|LS483399\|CRISPRCasFinder	749816-749857	42	MK448850	Streptococcus phage Javan132, complete genome	12709-12750	11	0.738

1. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

2. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccactctggataaggtctga	Protospacer
.   ***********************.******.  *. **

3. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

4. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

5. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccactctggataaggtctga	Protospacer
.   ***********************.******.  *. **

6. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

7. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

8. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

9. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

10. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

11. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

12. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

13. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

14. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctattatgttttaagacaccactctggataaggtctga	Protospacer
.   ** ********************.******.  *. **

15. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

16. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

17. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

18. spacer 1.1|749816|42|LS483399|CRISPRCasFinder matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30450 : 42820

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQG50210.1\|30450_34224_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.0e-39	26.7
SQG50214.1\|34384_35839_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	32.7
SQG50217.1\|35866_36889_+	phosphoribosylaminoimidazole synthetase	A0A0E3FGG1	Synechococcus_phage	2.4e-63	41.7
SQG50219.1\|37056_37611_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
SQG50221.1\|37794_39342_+	IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase	E3SNU8	Prochlorococcus_phage	2.8e-44	51.8
SQG50222.1\|39400_40525_-	bacterial SH3 domain protein	F8HGP2	Streptococcus_phage	1.0e-06	28.6
SQG50224.1\|40777_42043_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
SQG50226.1\|42208_42820_+	phosphoribosyl carboxyaminoimidazole mutase	A0A2P0VNU7	Tetraselmis_virus	3.1e-18	42.3

DBSCAN-SWA_2

317239 : 372914

Streptococcus_phage(33.33%)

protease,bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQG51053.1\|317239_317830_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
SQG51055.1\|318321_318597_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQG51057.1\|318845_319481_+	thymidylate kinase	M1PSC7	Streptococcus_phage	9.2e-66	63.9
SQG51060.1\|319498_320374_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
SQG51062.1\|320392_320632_+	Tpl protein	NA	NA	NA	NA
SQG51063.1\|321035_321359_+	DNA replication initiation control protein	M1PFV3	Streptococcus_phage	1.3e-28	59.4
SQG51065.1\|321363_322227_+	corrin/porphyrin methyltransferase	M1PLC5	Streptococcus_phage	5.5e-114	74.3
SQG51068.1\|322253_322646_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQG51069.1\|322692_323322_-	copper homeostasis protein	NA	NA	NA	NA
SQG51071.1\|323621_323978_+	arsenate reductase	M1PLC0	Streptococcus_phage	6.3e-40	65.8
SQG51073.1\|324051_324879_-	3'-exo-deoxyribonuclease	M1PSC0	Streptococcus_phage	4.5e-129	79.3
SQG51075.1\|325112_326294_+	L-lactate oxidase	NA	NA	NA	NA
SQG51077.1\|326559_331509_+	LPXTG-motif cell wall anchor domain protein	NA	NA	NA	NA
SQG51079.1\|332280_332988_+	permease	NA	NA	NA	NA
SQG51082.1\|333230_335228_+\|tRNA	methionyl-tRNA synthetase	A0A1V0SHR2	Klosneuvirus	1.7e-86	35.0
SQG51084.1\|335722_336736_+	ribonucleotide-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	7.2e-97	53.0
SQG51086.1\|336739_337228_+	nrdI protein	R4JF54	Bacillus_phage	1.3e-11	37.5
SQG51089.1\|337194_339375_+	ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.8e-170	43.1
SQG51091.1\|339578_340331_-	ADP-ribosyltransferase	NA	NA	NA	NA
SQG51093.1\|340787_341183_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQG51096.1\|341399_341651_+	hypothetical membrane spanning protein	NA	NA	NA	NA
SQG51099.1\|341745_342360_-	phage protein	NA	NA	NA	NA
SQG51101.1\|342720_342957_+	Protein of uncharacterised function (DUF2829)	NA	NA	NA	NA
SQG51103.1\|342949_343648_+	3-ketoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.2e-10	25.2
SQG51107.1\|343723_344683_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
SQG51109.1\|345015_346353_+	phosphoglycerate transporter protein	NA	NA	NA	NA
SQG51112.1\|346526_347909_+	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L4K9	Tupanvirus	3.8e-32	36.4
SQG51114.1\|347939_348494_+	ADP-ribose pyrophosphatase	NA	NA	NA	NA
SQG51117.1\|348493_348745_+	membrane protein	NA	NA	NA	NA
SQG51119.1\|348764_349460_+	MTA/SAH nucleosidase	NA	NA	NA	NA
SQG51122.1\|349610_349952_+	Uncharacterised protein	NA	NA	NA	NA
SQG51125.1\|350050_350698_-	metalloregulator ScaR	NA	NA	NA	NA
SQG51128.1\|350843_351776_+	manganese-binding protein	NA	NA	NA	NA
SQG51129.1\|351839_352565_+	manganese transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
SQG51135.1\|352565_353420_+	ABC 3 transport family protein	NA	NA	NA	NA
SQG51137.1\|353567_354374_-	cyclophilin type peptidyl-prolyl cis-trans isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
SQG51139.1\|354590_356996_+	cell division protein FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
SQG51141.1\|357065_357419_-	integral membrane protein	NA	NA	NA	NA
SQG51143.1\|357662_358088_+	50S ribosomal protein L11	NA	NA	NA	NA
SQG51145.1\|358193_358883_+	50S ribosomal protein L1	NA	NA	NA	NA
SQG51147.1\|359204_359933_+	uridylate kinase	NA	NA	NA	NA
SQG51149.1\|359961_360519_+	ribosome recycling factor	NA	NA	NA	NA
SQG51151.1\|360627_361485_+	s1 RNA binding domain	NA	NA	NA	NA
SQG51153.1\|361557_362067_+	methionine sulfoxide reductase A	NA	NA	NA	NA
SQG51155.1\|362063_362279_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQG51157.1\|362434_363604_+	lysM domain protein	A0A0E3XB61	Gordonia_phage	5.5e-16	40.5
SQG51159.1\|363916_365689_+	myosin-cross-reactive antigen	NA	NA	NA	NA
SQG51161.1\|365847_366900_+	phosphate starvation-induced protein	W8D063	Erwinia_phage	1.2e-46	50.0
SQG51163.1\|366945_367521_+	uracil DNA glycosylase superfamily protein	NA	NA	NA	NA
SQG51165.1\|367628_368177_+\|protease	metalloprotease	NA	NA	NA	NA
SQG51167.1\|368157_368565_+	diacylglycerol kinase	NA	NA	NA	NA
SQG51169.1\|368684_369581_+	GTP-binding protein Era	NA	NA	NA	NA
SQG51171.1\|369600_370077_+	phosphohydrolase	NA	NA	NA	NA
SQG51173.1\|370382_370637_-	Uncharacterised protein	NA	NA	NA	NA
SQG51175.1\|371034_371169_+\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQG51179.1\|371281_371464_+\|bacteriocin	bacteriocin class II with double-glycine leader peptide family protein	NA	NA	NA	NA
SQG51181.1\|372153_372369_-\|transposase	transposase	NA	NA	NA	NA
SQG51183.1\|372686_372914_+\|bacteriocin	bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_3

598818 : 669990

Streptococcus_phage(19.23%)

transposase,head,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQG51624.1\|598818_601029_-	phosphoglycerol transferase	W6LM83	Streptococcus_phage	1.4e-267	68.6
SQG51626.1\|601136_602300_+	SAM-dependent methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
SQG51628.1\|602296_602983_+	3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
SQG51630.1\|603076_604243_+	chorismate synthase	A0A291AU41	Pandoravirus	2.6e-34	33.1
SQG51632.1\|604303_604645_+	hypothetical cytosolic protein	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
SQG51634.1\|604865_606218_+	glutathione reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.0
SQG51636.1\|606305_607574_-	folylpolyglutamate synthase	NA	NA	NA	NA
SQG51638.1\|607603_608044_-	membrane protein	NA	NA	NA	NA
SQG51639.1\|608278_609421_+	aminotransferase class-V family protein	H7BUW1	unidentified_phage	3.5e-15	32.1
SQG51641.1\|609432_610647_+	thiamine biosynthesis protein thiI	NA	NA	NA	NA
SQG51643.1\|610684_611977_+	metallophosphatase	A0A2H4JC87	uncultured_Caudovirales_phage	2.9e-34	30.8
SQG51645.1\|611988_612972_-\|transposase	transposase	H7BW61	unidentified_phage	3.5e-32	35.0
SQG51647.1\|613276_613591_+	50S ribosomal protein L21	NA	NA	NA	NA
SQG51648.1\|613602_613929_+	hypothetical ribosome-associated protein	NA	NA	NA	NA
SQG51650.1\|613956_614250_+	LSU ribosomal protein L27p	NA	NA	NA	NA
SQG51652.1\|614395_614506_+	Uncharacterised protein	NA	NA	NA	NA
SQG51654.1\|614606_615521_+	LysR family transcriptional regulator	NA	NA	NA	NA
SQG51656.1\|615517_615976_+	signal peptidase II	NA	NA	NA	NA
SQG51658.1\|615965_616856_+	ribosomal large subunit pseudouridine synthase D	A0A2H4UV25	Bodo_saltans_virus	3.6e-07	25.3
SQG51660.1\|617251_617773_+	Uracil phosphoribosyltransferase / Pyrimidine operon regulatory protein pyrR	NA	NA	NA	NA
SQG51661.1\|617788_619048_+	uracil permease	Q9KX94	Enterobacteria_phage	2.1e-61	36.2
SQG51664.1\|619057_620044_+	aspartate carbamoyltransferase catalytic subunit	M1HGA5	Paramecium_bursaria_Chlorella_virus	3.2e-25	32.6
SQG51666.1\|620077_621160_+	carbamoyl phosphate synthase small subunit	R4TGJ8	Halovirus	4.7e-62	36.9
SQG51667.1\|621405_624582_+	carbamoyl-phosphate synthase large chain	NA	NA	NA	NA
SQG51669.1\|624757_626029_+	RND family efflux transporter MFP subunit	NA	NA	NA	NA
SQG51671.1\|626028_626739_+	bacitracin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.5e-37	43.0
SQG51673.1\|626750_627971_+	permease family protein	NA	NA	NA	NA
SQG51675.1\|628224_629958_+	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
SQG51677.1\|630084_630357_+	30S ribosomal protein S16	NA	NA	NA	NA
SQG51679.1\|630366_630606_+	RNA binding protein	NA	NA	NA	NA
SQG51681.1\|631538_634565_+	LPXTG-motif cell wall anchor domain protein	NA	NA	NA	NA
SQG51683.1\|634584_634986_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
SQG51685.1\|635165_636041_-	cation diffusion facilitator transporter family protein	NA	NA	NA	NA
SQG51686.1\|636176_636698_+	transcriptional regulator, TetR family	NA	NA	NA	NA
SQG51688.1\|636912_637431_+	16S rRNA-processing protein	NA	NA	NA	NA
SQG51690.1\|637420_638152_+\|tRNA	tRNA (guanine-N(1)-)-methyltransferase	NA	NA	NA	NA
SQG51692.1\|638151_639144_+	thioredoxin reductase	Q9JRK7	Streptococcus_phage	8.2e-29	54.9
SQG51695.1\|639323_640382_+	regulatory protein	NA	NA	NA	NA
SQG51697.1\|640394_641318_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
SQG51699.1\|641617_642286_+	deoR-like helix-turn-helix domain-containing protein	A0A077SK06	Escherichia_phage	6.3e-17	32.2
SQG51701.1\|642282_643194_+	1-phosphofructokinase	NA	NA	NA	NA
SQG51703.1\|643190_645137_+	PTS system fructose-specific transporter subunit IIABC	NA	NA	NA	NA
SQG51704.1\|645235_645829_+	N-acetylmuramidase	A0A249Y0X5	Enterococcus_phage	3.5e-11	33.8
SQG51706.1\|645979_646687_+	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q332B8	Clostridium_botulinum_C_phage	1.9e-11	36.4
SQG51708.1\|646743_646962_-\|transposase	degenerate transposase	A0A1B1P773	Bacillus_phage	2.7e-09	55.9
SQG51710.1\|647643_648546_-\|protease	igG-degrading protease	NA	NA	NA	NA
SQG51712.1\|649050_649227_+	nucleoside diphosphate kinase	NA	NA	NA	NA
SQG51715.1\|649454_649835_+\|transposase	transposase	NA	NA	NA	NA
SQG51716.1\|649834_650683_+	degV family protein	NA	NA	NA	NA
SQG51718.1\|650807_652016_+\|head	poly A polymerase head domain-containing protein	H7BUW3	unidentified_phage	6.9e-38	45.0
SQG51720.1\|652012_653890_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	6.7e-64	31.5
SQG51722.1\|654781_655192_+	polypeptide deformylase family protein	E3SLL2	Synechococcus_phage	6.9e-06	30.6
SQG51725.1\|655272_657285_-	5'-nucleotidase	NA	NA	NA	NA
SQG51727.1\|657504_658155_+	GTP pyrophosphokinase	NA	NA	NA	NA
SQG51729.1\|658157_658826_+	two-component response regulator	W8CYM9	Bacillus_phage	2.3e-19	28.8
SQG51731.1\|658834_660067_+	two component system histidine kinase	NA	NA	NA	NA
SQG51734.1\|660360_661239_+	mevalonate kinase	NA	NA	NA	NA
SQG51737.1\|661220_662165_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
SQG51739.1\|662157_663171_+	phosphomevalonate kinase	NA	NA	NA	NA
SQG51742.1\|663157_664147_+	isopentenyl pyrophosphate isomerase	NA	NA	NA	NA
SQG51744.1\|664376_665654_-	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
SQG51746.1\|665640_666816_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
SQG51747.1\|667024_667864_+	thymidylate synthase	U5J9N5	Bacillus_phage	1.7e-83	53.2
SQG51748.1\|667943_668441_+	dihydrofolate reductase	W5QU76	Bacillus_phage	1.1e-10	34.4
SQG51749.1\|668460_668631_+	hypothetical membrane associated protein	NA	NA	NA	NA
SQG51750.1\|668760_669990_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.7e-137	60.5

DBSCAN-SWA_4

927429 : 1023394

114

Streptococcus_phage(57.97%)

protease,terminase,portal,tail,transposase,integrase

attL 942783:942842|attR 986159:986257

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQG52311.1\|927429_928563_-\|transposase	transposase	NA	NA	NA	NA
SQG52313.1\|928715_929447_-	Mannitol-1-phosphate 5-dehydrogenase, MtlD	NA	NA	NA	NA
SQG52315.1\|929569_931384_-	glutamine-fructose-6-phosphate transaminase (isomerizing)	A0A1J0F994	Only_Syngen_Nebraska_virus	2.8e-99	37.4
SQG52318.1\|931655_933104_+	Phage-associated cell wall hydrolase	A0A1X9I5T2	Streptococcus_phage	4.6e-254	91.5
SQG52320.1\|933116_933674_-	Signal peptidase I	NA	NA	NA	NA
SQG52321.1\|933803_935306_-	pyruvate kinase	NA	NA	NA	NA
SQG52323.1\|935368_936382_-	6-phosphofructokinase	NA	NA	NA	NA
SQG52325.1\|936461_939572_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	7.1e-119	29.9
SQG52327.1\|939756_940128_+	GntR family transcriptional regulator	NA	NA	NA	NA
SQG52329.1\|940127_940826_+	ABC transporter family protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
SQG52331.1\|940835_941621_+	ABC transporter permease protein	NA	NA	NA	NA
SQG52333.1\|941747_942362_-	membrane protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
942783:942842	attL	NA	NA	NA	NA
SQG52335.1\|942952_943141_-	paratox	A3F673	Streptococcus_phage	1.0e-20	83.1
SQG52337.1\|943379_944180_+	streptodornase	NA	NA	NA	NA
SQG52339.1\|944450_944885_+	phage membrane protein	NA	NA	NA	NA
SQG52341.1\|944952_945597_-	bacterial SH3 domain protein	A7J2B5	Streptococcus_phage	6.8e-93	76.7
SQG52344.1\|945755_946400_-	AP2 domain protein	A0A2H4J2S8	uncultured_Caudovirales_phage	4.7e-33	35.4
SQG52345.1\|946632_947190_-	lysin	Q938J4	Temperate_phage	1.8e-97	91.9
SQG52347.1\|947305_947533_-	phage protein	A7J2B3	Streptococcus_phage	5.8e-31	98.7
SQG52349.1\|947529_947802_-	phage membrane protein	A7J2B2	Streptococcus_phage	5.0e-37	93.3
SQG52351.1\|947811_948429_-	phage protein	Q938J7	Temperate_phage	1.5e-76	88.3
SQG52353.1\|948431_948863_-	phage protein	Q938J8	Temperate_phage	1.1e-73	100.0
SQG52355.1\|948874_950890_-	Phage infection protein	Q938J9	Temperate_phage	2.2e-182	72.6
SQG52357.1\|950902_951928_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	6.2e-173	93.5
SQG52359.1\|951924_954072_-	Phage endopeptidase	Q938K1	Temperate_phage	0.0e+00	93.7
SQG52361.1\|954068_954776_-	phage protein	Q938K2	Temperate_phage	1.6e-90	68.5
SQG52363.1\|954775_958699_-\|tail	phage tail protein	J7KDT4	Streptococcus_phage	2.2e-250	49.6
SQG52365.1\|958711_958876_-	phage protein	J7KBS0	Streptococcus_phage	6.9e-10	84.6
SQG52367.1\|958907_959234_-	phage protein	J7KK85	Streptococcus_phage	6.4e-39	75.0
SQG52369.1\|959286_959898_-\|tail	major tail protein	J7KKC8	Streptococcus_phage	1.9e-76	75.1
SQG52371.1\|959914_960340_-	phage protein	J7KBZ9	Streptococcus_phage	5.9e-69	85.8
SQG52373.1\|960336_960714_-	phage protein	J7KDM3	Streptococcus_phage	1.5e-47	76.0
SQG52375.1\|960710_961058_-	phage protein	J7KJ42	Streptococcus_phage	2.6e-46	80.9
SQG52377.1\|961054_961357_-	phage protein	J7KC36	Streptococcus_phage	3.6e-44	90.8
SQG52378.1\|961534_962722_-	phage protein	J7KJ82	Streptococcus_phage	3.9e-179	84.3
SQG52380.1\|962746_963412_-\|protease	phage ClpP protease	M1Q115	Streptococcus_phage	2.1e-92	78.1
SQG52382.1\|963389_964610_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	2.4e-187	82.2
SQG52384.1\|964678_965422_-	antirepressor	M1PKL6	Streptococcus_phage	9.1e-73	56.9
SQG52386.1\|965423_965672_-	Uncharacterised protein	NA	NA	NA	NA
SQG52388.1\|965786_965966_-	Uncharacterised protein	M1NRK8	Streptococcus_phage	2.6e-18	79.7
SQG52390.1\|966050_966320_-	phage protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.3e-34	84.1
SQG52392.1\|966312_966483_-	phage protein	J7KK43	Streptococcus_phage	3.9e-08	56.2
SQG52394.1\|966479_968234_-\|terminase	phage terminase, large subunit	J7KKD1	Streptococcus_phage	0.0e+00	98.3
SQG52396.1\|968248_968716_-\|terminase	phage terminase, small subunit	J7KC46	Streptococcus_phage	4.3e-81	97.4
SQG52398.1\|968887_969226_-	Phage endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
SQG52399.1\|969772_970207_-	autolysin regulatory protein	J7KDQ1	Streptococcus_phage	4.5e-72	95.8
SQG52401.1\|970231_970660_-	phage protein	A0A097PAV5	Streptococcus_pyogenes_phage	8.2e-10	38.4
SQG52404.1\|970662_971295_-	phage protein	L0P368	Streptococcus_phage	3.4e-81	66.2
SQG52406.1\|971296_971581_-	phage protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.1e-34	84.0
SQG52408.1\|971577_971991_-	phage protein	Q938M1	Temperate_phage	2.6e-37	66.7
SQG52410.1\|971987_972272_-	phage protein	A0A1P8VVP5	Streptococcus_phage	1.3e-48	96.8
SQG52412.1\|972265_972517_-	phage protein	A0A1P8VVV4	Streptococcus_phage	1.3e-39	92.8
SQG52414.1\|972513_972870_-	phage protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
SQG52416.1\|972853_973204_-	phage protein	A0A1P8VVL5	Streptococcus_phage	9.9e-46	88.5
SQG52417.1\|973157_974027_-	phage protein	A0A1P8BME8	Lactococcus_phage	5.8e-103	65.6
SQG52419.1\|974295_975849_-	bacteriophage resistance protein	A0A1P8BM51	Lactococcus_phage	1.5e-210	70.6
SQG52421.1\|975866_976349_-	phage protein	A0A1P8BM40	Lactococcus_phage	1.7e-59	70.7
SQG52423.1\|976353_977718_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	3.8e-194	72.1
SQG52425.1\|977792_978476_-	phage protein	J7KC09	Streptococcus_phage	1.8e-123	97.7
SQG52428.1\|978472_978757_-	phage protein	NA	NA	NA	NA
SQG52429.1\|978753_978948_-	phage protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
SQG52432.1\|978947_979277_-	phage protein	J7KBZ0	Streptococcus_phage	7.9e-13	41.8
SQG52435.1\|979260_979374_-	Uncharacterised protein	A0A097PAT6	Streptococcus_pyogenes_phage	9.9e-08	75.0
SQG52438.1\|979357_979495_-	phage protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
SQG52440.1\|979491_979788_-	phage protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
SQG52442.1\|979866_980052_-	phage regulatory protein	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
SQG52445.1\|980218_980458_+	phage protein	NA	NA	NA	NA
SQG52447.1\|980606_980831_+	Uncharacterised protein	NA	NA	NA	NA
SQG52449.1\|980827_980962_-	Uncharacterised protein	NA	NA	NA	NA
SQG52452.1\|980998_981199_-	helix-turn-helix family protein	A0A141E205	Streptococcus_phage	2.1e-08	61.4
SQG52454.1\|981295_982075_+	Uncharacterised protein	A0A1S5S7L0	Streptococcus_phage	1.4e-44	51.7
SQG52456.1\|982010_982175_-	Uncharacterised protein	NA	NA	NA	NA
SQG52458.1\|982208_982367_-	Uncharacterised protein	J7KH24	Streptococcus_phage	2.2e-21	90.4
SQG52460.1\|982425_982641_+	Uncharacterised protein	J7KBX0	Streptococcus_phage	8.8e-29	97.1
SQG52462.1\|982626_982776_-	Uncharacterised protein	J7KH12	Streptococcus_phage	4.3e-19	91.8
SQG52463.1\|983131_983956_+	phage transcriptional repressor	A0A097PBE5	Streptococcus_pyogenes_phage	8.4e-120	84.8
SQG52465.1\|983968_984778_+	phage protein	J7KDP1	Streptococcus_phage	3.8e-24	35.8
SQG52466.1\|984834_984987_-	phage protein	NA	NA	NA	NA
SQG52468.1\|985027_986116_+\|integrase	integrase	Q38159	Streptococcus_phage	4.2e-204	99.4
SQG52469.1\|986478_987099_+	phage protein	NA	NA	NA	NA
986159:986257	attR	NA	NA	NA	NA
SQG52471.1\|987355_989620_-	glycogen phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
SQG52472.1\|989654_991148_-	4-alpha-glucanotransferase	NA	NA	NA	NA
SQG52474.1\|991261_992281_-	LacI family transcription regulator	C6ZCU4	Enterobacteria_phage	2.5e-17	28.1
SQG52476.1\|992524_993772_+	maltose/maltodextrin-binding protein	NA	NA	NA	NA
SQG52477.1\|994045_995407_+	maltose/maltodextrin ABC transport system permease	NA	NA	NA	NA
SQG52479.1\|995406_996243_+	maltose transport system permease	NA	NA	NA	NA
SQG52480.1\|996423_996693_+\|transposase	transposase	NA	NA	NA	NA
SQG52482.1\|996670_997204_+\|transposase	truncated transposase	Q9MBM9	Staphylococcus_prophage	4.9e-28	39.6
SQG52483.1\|997717_998701_-	alpha/beta fold family hydrolase	NA	NA	NA	NA
SQG52485.1\|998731_999982_-	D-alanine transfer from undecaprenol-phosphate to the poly(Glycerophosphate) chain	NA	NA	NA	NA
SQG52486.1\|999974_1000214_-	D-alanine-poly(phosphoribitol) ligase subunit 2	NA	NA	NA	NA
SQG52488.1\|1000231_1001488_-	Protein dltB	NA	NA	NA	NA
SQG52489.1\|1001484_1003023_-	D-alanine--poly(phosphoribitol) ligase subunit 1	A0A2K9KZV5	Tupanvirus	6.5e-41	28.2
SQG52491.1\|1003034_1003178_-	D-alanyl-lipoteichoic acid biosynthesis protein DltX	NA	NA	NA	NA
SQG52493.1\|1003440_1005432_-	excinuclease ABC subunit B	NA	NA	NA	NA
SQG52494.1\|1005624_1007799_+	glutamine-binding protein/glutamine transpor tsystem permease protein	NA	NA	NA	NA
SQG52496.1\|1007798_1008539_+	glutamine transport ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	1.5e-35	42.1
SQG52498.1\|1008686_1008839_-	Uncharacterised protein	NA	NA	NA	NA
SQG52499.1\|1008835_1010215_-	PTS system cellobiose-specific transporter subunit IIC	NA	NA	NA	NA
SQG52500.1\|1010407_1010842_-	Domain of uncharacterised function (DUF3284)	NA	NA	NA	NA
SQG52502.1\|1010838_1011174_-	PTS system cellobiose-specific transporter subunit IIA	NA	NA	NA	NA
SQG52504.1\|1011176_1011488_-	PTS system cellobiose-specific component IIB	NA	NA	NA	NA
SQG52505.1\|1011510_1013505_-	PTS system mannitol (cryptic)-specific transporter subunit IIA	NA	NA	NA	NA
SQG52507.1\|1013610_1014705_-	outer surface protein	NA	NA	NA	NA
SQG52508.1\|1014713_1016114_-	beta-glucosidase	NA	NA	NA	NA
SQG52511.1\|1016338_1017034_+	nicotinamide mononucleotide transporter	NA	NA	NA	NA
SQG52513.1\|1017038_1017197_-	hypothetical cytosolic protein	NA	NA	NA	NA
SQG52515.1\|1017265_1018579_-	GTPase ObgE	NA	NA	NA	NA
SQG52516.1\|1018635_1018764_-	membrane protein	NA	NA	NA	NA
SQG52517.1\|1019006_1019522_+\|transposase	transposase	NA	NA	NA	NA
SQG52518.1\|1019541_1020354_+\|transposase	transposase	A0A1B1P773	Bacillus_phage	3.7e-59	49.0
SQG52519.1\|1020616_1021489_-	nicotinate-nucleotide pyrophosphorylase	NA	NA	NA	NA
SQG52520.1\|1021712_1023023_+	membrane protein	NA	NA	NA	NA
SQG52521.1\|1023100_1023394_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1062679 : 1148760

102

Streptococcus_phage(43.55%)

protease,terminase,capsid,head,tRNA,tail,transposase,integrase

attL 1105004:1105023|attR 1146145:1146164

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SQG52558.1\|1062679_1062973_+\|transposase	transposase	NA	NA	NA	NA
SQG52559.1\|1063005_1063575_+\|integrase	integrase core domain protein	A0A1P8CWQ3	Bacillus_phage	6.4e-26	37.9
SQG52560.1\|1063614_1063830_+	Transposase	U5P429	Shigella_phage	4.5e-09	42.4
SQG52561.1\|1063926_1064622_-\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
SQG52562.1\|1064640_1065402_-	hypothetical membrane spanning protein	NA	NA	NA	NA
SQG52563.1\|1065398_1065614_-	XRE family transcriptional regulator	NA	NA	NA	NA
SQG52564.1\|1065654_1065789_-	Uncharacterised protein	NA	NA	NA	NA
SQG52565.1\|1065974_1068593_-\|tRNA	Alanyl-tRNA synthetase	A0A1V0SK38	Klosneuvirus	5.1e-62	34.1
SQG52566.1\|1068979_1070035_-	foldase protein prsA 1	NA	NA	NA	NA
SQG52567.1\|1070097_1070769_-	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	2.4e-08	27.2
SQG52568.1\|1070870_1072067_-	major facilitator superfamily protein	NA	NA	NA	NA
SQG52569.1\|1072441_1074247_-	oligoendopeptidase F	NA	NA	NA	NA
SQG52570.1\|1074259_1075222_-	competence CoiA-like family protein	NA	NA	NA	NA
SQG52571.1\|1075516_1076233_-	16S pseudouridylate synthetase	NA	NA	NA	NA
SQG52572.1\|1076351_1077056_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
SQG52573.1\|1077257_1078286_+\|tRNA	S-adenosylmethionine-tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
SQG52574.1\|1078325_1079513_+	hypothetical cytosolic protein	NA	NA	NA	NA
SQG52575.1\|1079626_1080217_-	S11 family peptidase	NA	NA	NA	NA
SQG52576.1\|1080213_1080462_-	lipoprotein	NA	NA	NA	NA
SQG52577.1\|1080446_1080674_-	Uncharacterised protein	NA	NA	NA	NA
SQG52578.1\|1080840_1081446_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.8e-58	53.2
SQG52579.1\|1081542_1082583_-	DNA polymerase III subunit delta	NA	NA	NA	NA
SQG52580.1\|1082653_1084897_-	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.8e-55	59.2
SQG52581.1\|1084877_1085540_-	comE operon 1 domain-containing protein	NA	NA	NA	NA
SQG52582.1\|1085739_1086480_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
SQG52583.1\|1086519_1087374_+	methyltransferase	NA	NA	NA	NA
SQG52584.1\|1087363_1087642_+	GIY-YIG catalytic domain-containing protein	W8W2G4	Invertebrate_iridovirus	1.8e-05	36.0
SQG52585.1\|1087665_1089666_-	Kup system potassium uptake protein	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	5.8e-66	34.0
SQG52586.1\|1089792_1091412_-	DEAD-box ATP-dependent RNA helicase CshA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.9e-59	36.5
SQG52587.1\|1091718_1093263_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	1.8e-35	29.0
SQG52588.1\|1093510_1094206_-	integral membrane family protein	NA	NA	NA	NA
SQG52589.1\|1094285_1095677_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
SQG52590.1\|1095867_1096914_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
SQG52591.1\|1097014_1097611_-	recombination protein	NA	NA	NA	NA
SQG52592.1\|1097622_1097838_-	Penicillin-binding protein	NA	NA	NA	NA
SQG52593.1\|1098397_1099177_-	formate transporter	NA	NA	NA	NA
SQG52594.1\|1099300_1099843_-	membrane protein	NA	NA	NA	NA
SQG52595.1\|1100003_1100525_-	3H domain-containing protein	NA	NA	NA	NA
SQG52597.1\|1100631_1101327_-	phosphoglyceromutase	NA	NA	NA	NA
SQG52600.1\|1101565_1102501_+	dihydroorotate dehydrogenase 1A	A0A1V0SH91	Hokovirus	1.3e-65	44.8
SQG52602.1\|1102800_1104663_-	putative heavy metal-transporting ATPase	E4ZFI9	Streptococcus_phage	5.4e-90	33.8
1105004:1105023	attL	NA	NA	NA	NA
SQG52604.1\|1105192_1105375_-	paratox	A3F673	Streptococcus_phage	2.0e-21	81.7
SQG52606.1\|1105614_1106373_+	DNA/RNA non-specific endonuclease family protein	NA	NA	NA	NA
SQG52609.1\|1106483_1107191_+	exotoxin type C	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
SQG52610.1\|1107259_1108012_-	phage-associated cell wall hydrolase	A3F665	Streptococcus_phage	2.1e-141	97.2
SQG52613.1\|1108013_1108346_-	N-acetylmuramoyl-L-alanine amidase	A3F664	Streptococcus_phage	5.7e-51	100.0
SQG52615.1\|1108347_1108677_-	Uncharacterised protein	A3F663	Streptococcus_phage	6.2e-50	99.0
SQG52617.1\|1108687_1109305_-	phage protein	Q938J7	Temperate_phage	3.3e-76	87.3
SQG52619.1\|1109307_1109739_-	phage protein	Q938J8	Temperate_phage	1.1e-73	100.0
SQG52621.1\|1109750_1111634_-	phage protein	Q938J9	Temperate_phage	8.0e-251	96.5
SQG52623.1\|1111648_1112668_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.7e-176	96.2
SQG52625.1\|1112664_1114809_-	Phage endopeptidase	Q938K1	Temperate_phage	0.0e+00	97.1
SQG52627.1\|1114805_1115522_-	phage protein	Q938K2	Temperate_phage	3.6e-135	98.7
SQG52630.1\|1115518_1118779_-	phage protein	Q938K3	Temperate_phage	0.0e+00	98.6
SQG52632.1\|1118768_1119350_-	bacteriophage Gp15 family protein	Q938K4	Temperate_phage	1.6e-104	98.4
SQG52634.1\|1119353_1119788_-	phage protein	Q938K5	Temperate_phage	2.9e-71	99.3
SQG52635.1\|1119826_1120312_-\|tail	major tail shaft protein	Q938K6	Temperate_phage	1.6e-86	100.0
SQG52637.1\|1120311_1120710_-\|capsid	minor capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
SQG52639.1\|1120706_1121063_-	phage protein	Q79S88	Temperate_phage	4.5e-62	100.0
SQG52642.1\|1121062_1121395_-\|capsid	minor capsid protein - phage associated	Q79S86	Temperate_phage	9.6e-59	100.0
SQG52643.1\|1121384_1121801_-	phage protein	Q938K7	Temperate_phage	1.3e-55	98.2
SQG52646.1\|1121854_1122673_-\|head	putative major head protein	Q79S85	Temperate_phage	4.0e-146	100.0
SQG52648.1\|1122676_1123285_-	phage protein	Q938K8	Temperate_phage	4.0e-95	95.0
SQG52650.1\|1123416_1123683_-	secreted phage protein	Q938K9	Temperate_phage	8.3e-37	95.5
SQG52652.1\|1123769_1123997_-	phage protein	NA	NA	NA	NA
SQG52654.1\|1123996_1125490_-\|capsid	phage minor capsid 2 family protein	Q938L1	Temperate_phage	3.1e-213	79.8
SQG52656.1\|1125494_1126946_-\|capsid	Minor capsid protein	Q938L2	Temperate_phage	6.1e-267	97.3
SQG52658.1\|1127010_1128222_-\|terminase	phage terminase	Q938L3	Temperate_phage	4.3e-221	97.6
SQG52660.1\|1128304_1129000_-	phage protein	A0A2H4J4R0	uncultured_Caudovirales_phage	1.7e-28	34.2
SQG52662.1\|1129119_1129536_-	phage protein	A7J289	Streptococcus_phage	7.3e-72	98.6
SQG52664.1\|1129532_1129724_-	phage protein	NA	NA	NA	NA
SQG52666.1\|1129794_1129980_-	Uncharacterised protein	NA	NA	NA	NA
SQG52668.1\|1129972_1130143_-	phage protein	A7J285	Streptococcus_phage	2.8e-22	98.1
SQG52670.1\|1130143_1131466_-	SNF2 family phage protein	A7J284	Streptococcus_phage	1.1e-249	96.8
SQG52672.1\|1131462_1131738_-	phage protein	A7J283	Streptococcus_phage	2.9e-45	96.7
SQG52674.1\|1132123_1134508_-	phage DNA primase/helicase protein	A7J282	Streptococcus_phage	8.2e-277	94.6
SQG52676.1\|1134512_1136435_-	phage DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	98.4
SQG52678.1\|1136477_1137035_-	phage protein	D2J040	Enterococcus_phage	8.6e-52	59.0
SQG52680.1\|1137049_1138207_-	phage protein	A7J278	Streptococcus_phage	8.8e-216	97.7
SQG52682.1\|1138206_1138506_-	phage protein	A7J277	Streptococcus_phage	1.8e-43	100.0
SQG52685.1\|1138594_1138798_-	phage protein	A7J276	Streptococcus_phage	1.6e-32	98.5
SQG52687.1\|1139141_1139291_-	phage protein	A7J275	Streptococcus_phage	3.8e-15	90.0
SQG52689.1\|1139287_1139566_-	phage protein	A7J274	Streptococcus_phage	2.1e-43	93.5
SQG52692.1\|1139669_1139873_-	phage protein	NA	NA	NA	NA
SQG52694.1\|1139865_1140036_-	phage protein	A7J273	Streptococcus_phage	2.9e-19	87.5
SQG52695.1\|1140037_1140349_-	excisionase	A0A1S5SA25	Streptococcus_phage	1.4e-43	78.6
SQG52697.1\|1140455_1140671_+	Uncharacterised protein	A0A1S5SA41	Streptococcus_phage	1.9e-15	61.4
SQG52700.1\|1140644_1140893_-	Uncharacterised protein	A0A141E1M0	Streptococcus_phage	1.6e-26	69.5
SQG52702.1\|1140972_1141182_+	Uncharacterised protein	NA	NA	NA	NA
SQG52704.1\|1141323_1141584_+	Uncharacterised protein	M1PS67	Streptococcus_phage	5.8e-27	70.9
SQG52706.1\|1141512_1141671_-	Uncharacterised protein	NA	NA	NA	NA
SQG52708.1\|1141682_1142420_-	prophage LambdaSa1, antirepressor	A0A2H4IZX7	uncultured_Caudovirales_phage	3.6e-90	68.3
SQG52711.1\|1142431_1142623_-	phage protein	A7J270	Streptococcus_phage	4.0e-25	92.1
SQG52713.1\|1142929_1143079_+	Uncharacterised protein	NA	NA	NA	NA
SQG52715.1\|1143851_1144124_+	Cro/CI family phage transcriptional regulator	Q7Y4M0	Streptococcus_phage	2.2e-32	73.9
SQG52717.1\|1144127_1144508_+	peptidase	A0A1S5SFH2	Streptococcus_phage	8.0e-41	61.1
SQG52719.1\|1144519_1144786_+	phage protein	NA	NA	NA	NA
SQG52721.1\|1144914_1146057_+\|integrase	phage integrase family protein	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
SQG52723.1\|1146146_1146422_-	DNA-binding protein HU 1	A7KV42	Bacillus_phage	2.6e-25	73.0
1146145:1146164	attR	NA	NA	NA	NA
SQG52725.1\|1146520_1147108_-	membrane protein	NA	NA	NA	NA
SQG52727.1\|1147085_1147946_-	GDSL family lipase	NA	NA	NA	NA
SQG52728.1\|1147920_1148760_-	degV family protein	A0A0N9SI50	Staphylococcus_phage	7.0e-13	35.7

DBSCAN-SWA_6

1244200 : 1289668

Streptococcus_phage(42.37%)

tail,portal,integrase,terminase

attL 1236677:1236692|attR 1303300:1303315

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1236677:1236692	attL	NA	NA	NA	NA
SQG52927.1\|1244200_1245556_-	RNA methyltransferase	A0A2K5B251	Erysipelothrix_phage	1.5e-73	33.0
SQG52929.1\|1245746_1245929_-	paratox	A3F673	Streptococcus_phage	4.4e-21	83.3
SQG52932.1\|1246166_1246967_+	streptodornase	NA	NA	NA	NA
SQG52935.1\|1247238_1247673_+	phage membrane protein	NA	NA	NA	NA
SQG52937.1\|1247722_1248589_-	phage protein	Q938J2	Temperate_phage	1.1e-133	99.7
SQG52940.1\|1248576_1249101_-	phage protein	Q938J3	Temperate_phage	4.0e-99	100.0
SQG52942.1\|1249240_1250443_-	phage associated protein	Q938J4	Temperate_phage	1.6e-241	99.8
SQG52945.1\|1250439_1250550_-	phage membrane protein	A7J2B4	Streptococcus_phage	1.8e-09	97.2
SQG52947.1\|1250553_1250739_-	phage protein	Q938J5	Temperate_phage	1.7e-25	100.0
SQG52950.1\|1250735_1251032_-	phage protein	Q938J6	Temperate_phage	7.5e-47	100.0
SQG53073.1\|1251042_1251654_-	phage protein	Q938J7	Temperate_phage	2.7e-91	100.0
SQG53075.1\|1251656_1252088_-	phage protein	Q938J8	Temperate_phage	1.1e-73	100.0
SQG53077.1\|1252099_1253983_-	phage protein	Q938J9	Temperate_phage	2.8e-256	100.0
SQG53079.1\|1253997_1255011_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.0e-184	99.7
SQG53082.1\|1255007_1257059_-	phage protein	A3F656	Streptococcus_phage	0.0e+00	84.9
SQG53084.1\|1257055_1257835_-\|tail	phage tail protein	A3F655	Streptococcus_phage	1.9e-65	54.0
SQG53086.1\|1257866_1261502_-	tape measure domain protein	C5IUK3	Streptococcus_phage	3.2e-86	41.4
SQG53089.1\|1261516_1261840_-	phage protein	A0A1P8BLR3	Lactococcus_phage	5.6e-11	40.6
SQG53091.1\|1261887_1262241_-	phage protein	Q77RZ7	Lactococcus_phage	5.5e-20	48.6
SQG53093.1\|1262294_1262963_-	phage protein	D7RWD5	Brochothrix_phage	3.5e-39	50.5
SQG53095.1\|1262972_1263362_-	phage protein	B5SP36	Lactococcus_phage	4.2e-45	68.2
SQG53098.1\|1263358_1263724_-	phage protein	A0A097BY98	Enterococcus_phage	5.9e-17	46.3
SQG53101.1\|1263704_1264013_-	phage protein	A0A2P1JTW8	Anoxybacillus_phage	7.4e-13	40.2
SQG53104.1\|1264009_1264363_-	phage protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
SQG53106.1\|1264376_1264619_-	phage protein	NA	NA	NA	NA
SQG53109.1\|1264628_1265711_-	phage protein	A0A2H4J022	uncultured_Caudovirales_phage	3.4e-105	57.1
SQG53111.1\|1265713_1266094_-	phage protein	A0A0K2CNR0	Brevibacillus_phage	1.8e-05	32.5
SQG53114.1\|1266103_1266637_-	phage protein	A0A141E0S7	Streptococcus_phage	6.8e-14	80.7
SQG53116.1\|1266780_1267047_-	phage protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.9e-25	70.5
SQG53120.1\|1267049_1267364_-	phage protein	M1PLI3	Streptococcus_phage	6.8e-38	72.8
SQG53121.1\|1267433_1267619_-	phage protein	NA	NA	NA	NA
SQG53125.1\|1267622_1269185_-	phage protein	U6E9F1	Streptococcus_phage	2.5e-48	44.2
SQG53128.1\|1269165_1270668_-\|portal	phage portal protein, SPP1 family	C9W9H5	Streptococcus_virus	1.9e-141	54.5
SQG53132.1\|1270679_1271987_-\|terminase	terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.0e-184	75.7
SQG53135.1\|1271964_1272396_-\|terminase	terminase	A0A1S5SCD2	Streptococcus_phage	2.2e-47	69.9
SQG53137.1\|1272494_1272680_+	phage protein	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
SQG53140.1\|1272731_1273109_+	phage protein	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
SQG53143.1\|1273246_1273708_-	Uncharacterised protein	NA	NA	NA	NA
SQG53145.1\|1273726_1274641_-	phage protein	NA	NA	NA	NA
SQG53148.1\|1275115_1275550_-	autolysin regulatory protein	J7KDQ1	Streptococcus_phage	2.6e-72	96.5
SQG53150.1\|1275860_1276028_-	Uncharacterised protein	J7KK59	Streptococcus_phage	1.1e-13	70.9
SQG53153.1\|1276024_1276192_-	phage protein	NA	NA	NA	NA
SQG53155.1\|1276188_1276740_-	Protein of uncharacterised function (DUF1642)	A0A1S5PS22	Streptococcus_phage	1.9e-11	33.0
SQG53158.1\|1276752_1277454_-	adenine-specific methyltransferase	A0A1S5SBM4	Streptococcus_phage	3.6e-103	75.9
SQG53161.1\|1277457_1277742_-	phage protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.0e-37	89.4
SQG53163.1\|1277738_1277915_-	Uncharacterised protein	NA	NA	NA	NA
SQG53166.1\|1277928_1278198_-	phage protein	A0A1P8VVR6	Streptococcus_phage	7.6e-46	96.6
SQG53168.1\|1278194_1278479_-	phage protein	Q938M3	Temperate_phage	5.4e-50	100.0
SQG53171.1\|1278472_1278724_-	phage protein	Q938M4	Temperate_phage	6.8e-41	100.0
SQG53173.1\|1278720_1279077_-	phage protein	A0A1P8VVP9	Streptococcus_phage	1.6e-51	85.6
SQG53176.1\|1279073_1279514_-	phage protein	A0A097PAS0	Streptococcus_pyogenes_phage	8.5e-79	97.3
SQG53178.1\|1279722_1280142_-	single-stranded DNA-binding protein ssb	Q938M7	Temperate_phage	2.4e-70	99.3
SQG53181.1\|1280134_1280809_-	Single-stranded DNA-binding protein	Q938M8	Temperate_phage	2.5e-106	100.0
SQG53183.1\|1280809_1281292_-	phage protein	Q938M9	Temperate_phage	8.2e-51	100.0
SQG53186.1\|1281313_1281568_-	phage protein	Q938N0	Temperate_phage	3.7e-42	98.8
SQG53190.1\|1281548_1281902_-	phage protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
SQG53193.1\|1281914_1282052_-	phage protein	J7KBQ4	Streptococcus_phage	2.7e-07	78.4
SQG53196.1\|1282042_1282825_-	DNA replication protein DnaC	A0A097PAQ0	Streptococcus_pyogenes_phage	1.0e-143	97.3
SQG53200.1\|1282811_1283615_-	DNA replication protein DnaC	A0A2P0VI76	Streptococcus_phage	2.4e-63	53.8
SQG53202.1\|1283730_1284174_-	Uncharacterised protein	NA	NA	NA	NA
SQG53205.1\|1284229_1284610_+	Uncharacterised protein	NA	NA	NA	NA
SQG53208.1\|1284599_1284872_-	Uncharacterised protein	NA	NA	NA	NA
SQG53210.1\|1285044_1285224_-	Uncharacterised protein	A0A1X9I5M8	Streptococcus_phage	1.2e-12	65.5
SQG53212.1\|1285354_1285489_-	phage protein	A0A1P8VVR9	Streptococcus_phage	9.6e-18	95.5
SQG53215.1\|1285519_1285771_-	phage protein	A0A1P8VVV6	Streptococcus_phage	7.6e-40	94.0
SQG53218.1\|1285870_1286089_-	Transcriptional regulator, Cro family	A0A1P8VVR5	Streptococcus_phage	5.9e-33	97.2
SQG53219.1\|1286276_1286636_+	Transcriptional regulator, MerR family	A0A1P8VVN3	Streptococcus_phage	1.7e-56	95.0
SQG53221.1\|1286619_1286997_+	cI-like repressor	A0A1P8VVK5	Streptococcus_phage	4.3e-55	79.2
SQG53223.1\|1287022_1288321_+	phage membrane protein	M1PLF9	Streptococcus_phage	1.1e-110	62.7
SQG53227.1\|1288501_1289668_+\|integrase	phage integrase	C5J953	Streptococcus_phage	2.4e-80	42.4
1303300:1303315	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage