CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LS483446	Helicobacter mustelae strain NCTC12198 genome assembly, chromosome: 1	2 crisprs	cas1,cas9,DEDDh,cas4,cas3	0	8	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LS483446_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483446_1

24706-25400

Consensus_repeat	Method
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CRISPRCasFinder
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CRT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	PILER-CR

10 spacers

cas2,cas1,cas9,DEDDh

The CRISPR arrays of LS483446_1

>merge|LS483446|1|24706-25400|CRISPRCasFinder,CRT,PILER-CR
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTAGAGTTAGTAGTTCTCTTTTTCTTTCCTGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTGAGCTATACGGATTGCAAAGATTCTTTTTGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATGCTGCGGTCTTGATTATTGGTAGCATTCGTGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTTTAAAGTTTTGCGGCGATGAACTGCATGTGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATCTTGCTCCACCCACACGTTATACTTGCTAGGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTCAACGCCTGCAATATTGTAATTAATCTTCGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATCCCTTCTTGGTTTTGATGCCACTCTAAACGGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTCGTAGCGTTATCTTTCCCATGCACAGCATGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTGATGCAGTTGCAACACGTAGAAAGAGTCTGTTTTAGCCACTTCATAAATATGTTTATGCTAAAATTTGGAAAAACTTTACATAGAGACCCGCATAGTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT

>LS483446|1|1|24706-25400|CRISPRCasFinder
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TAGAGTTAGTAGTTCTCTTTTTCTTTCCT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TGAGCTATACGGATTGCAAAGATTCTTTTT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	GCTGCGGTCTTGATTATTGGTAGCATTCGT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TTTAAAGTTTTGCGGCGATGAACTGCATGT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CTTGCTCCACCCACACGTTATACTTGCTAG
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TCAACGCCTGCAATATTGTAATTAATCTTC
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CCCTTCTTGGTTTTGATGCCACTCTAAACG
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TCGTAGCGTTATCTTTCCCATGCACAGCAT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TGATGCAGTTGCAACACGTAGAAAGAGTCT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TTGGAAAAACTTTACATAGAGACCCGCATA
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT

>LS483446|1|1|24706-25400|CRT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TAGAGTTAGTAGTTCTCTTTTTCTTTCCT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TGAGCTATACGGATTGCAAAGATTCTTTTT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	GCTGCGGTCTTGATTATTGGTAGCATTCGT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TTTAAAGTTTTGCGGCGATGAACTGCATGT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CTTGCTCCACCCACACGTTATACTTGCTAG
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TCAACGCCTGCAATATTGTAATTAATCTTC
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CCCTTCTTGGTTTTGATGCCACTCTAAACG
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TCGTAGCGTTATCTTTCCCATGCACAGCAT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TGATGCAGTTGCAACACGTAGAAAGAGTCT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TTGGAAAAACTTTACATAGAGACCCGCATA
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT

>LS483446|1|1|24837-25400|PILER-CR
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	GCTGCGGTCTTGATTATTGGTAGCATTCGT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TTTAAAGTTTTGCGGCGATGAACTGCATGT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CTTGCTCCACCCACACGTTATACTTGCTAG
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TCAACGCCTGCAATATTGTAATTAATCTTC
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	CCCTTCTTGGTTTTGATGCCACTCTAAACG
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TCGTAGCGTTATCTTTCCCATGCACAGCAT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TGATGCAGTTGCAACACGTAGAAAGAGTCT
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT	TTGGAAAAACTTTACATAGAGACCCGCATA
GTTTTAGCCACTTCATAAATATGTTTATGCTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
LS483446.1\|SQH70804.1\|32194_33025_-\|fructose-1,6-bisphosphatase	unknown	unknown	gnl\|CDD\|236458
LS483446.1\|SQH70789.1\|11176_12004_-\|pyridoxal-phosphate-biosynthetic-protein	unknown	unknown	gnl\|CDD\|377117
LS483446.1\|SQH70788.1\|10241_11180_-\|pyridoxal-phosphate-biosynthetic-protein	unknown	unknown	gnl\|CDD\|179681
LS483446.1\|SQH70802.1\|30918_32001_-\|Uncharacterized-protein-conserved-in-archaea	unknown	unknown	gnl\|CDD\|224730
LS483446.1\|SQH70790.1\|12013_12712_-\|outer-membrane-protein	unknown	unknown	unknown
LS483446.1\|SQH70794.1\|21612_22329_-\|outer-membrane-protein	unknown	unknown	gnl\|CDD\|280099
LS483446.1\|SQH70803.1\|31997_32198_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH70798.1\|25512_25836_-\|CRISPR-associated-proteins	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LS483446.1\|SQH70796.1\|23165_24332_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|225139
LS483446.1\|SQH70800.1\|26717_29792_-\|CRISPR-associated-protein	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
LS483446.1\|SQH70791.1\|12722_13484_-\|outer-membrane-protein	unknown	unknown	unknown
LS483446.1\|SQH70807.1\|34775_35033_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH70801.1\|30140_30731_-\|outer-membrane-protein	unknown	unknown	gnl\|CDD\|280099
LS483446.1\|SQH70795.1\|22618_23017_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH70806.1\|33745_34489_+\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236281
LS483446.1\|SQH70787.1\|9614_10226_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH70792.1\|13576_15103_-\|TpsB-transporter	unknown	unknown	gnl\|CDD\|225387
LS483446.1\|SQH70805.1\|33107_33746_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|235515
LS483446.1\|SQH70793.1\|15282_21573_-\|haemagglutinin	unknown	unknown	gnl\|CDD\|368641
LS483446.1\|SQH70799.1\|25798_26725_-\|CRISPR-associated-protein	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694

Protein	Function_ID	Function_description	E-value
LS483446.1\|SQH70804.1\|32194_33025_-\|fructose-1,6-bisphosphatase	gnl\|CDD\|236458	PRK09293, PRK09293, class 1 fructose-bisphosphatase.	5.30525e-107
LS483446.1\|SQH70789.1\|11176_12004_-\|pyridoxal-phosphate-biosynthetic-protein	gnl\|CDD\|377117	pfam03740, PdxJ, Pyridoxal phosphate biosynthesis protein PdxJ. Members of this family belong to the PdxJ family that catalyzes the condensation of 1-deoxy-d-xylulose-5-phosphate (DXP) and 1-amino-3-oxo-4-(phosphohydroxy)propan-2-one to form pyridoxine 5'-phosphate (PNP). This reaction is involved in de novo synthesis of pyridoxine (vitamin B6) and pyridoxal phosphate.	1.42543e-112
LS483446.1\|SQH70788.1\|10241_11180_-\|pyridoxal-phosphate-biosynthetic-protein	gnl\|CDD\|179681	PRK03946, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Provisional.	0
LS483446.1\|SQH70802.1\|30918_32001_-\|Uncharacterized-protein-conserved-in-archaea	gnl\|CDD\|224730	COG1817, COG1817, Uncharacterized protein conserved in archaea [Function unknown].	3.02152e-40
LS483446.1\|SQH70798.1\|25512_25836_-\|CRISPR-associated-proteins	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.94719e-40
LS483446.1\|SQH70794.1\|21612_22329_-\|outer-membrane-protein	gnl\|CDD\|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	0.000280996
LS483446.1\|SQH70805.1\|33107_33746_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|235515	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated.	6.91666e-118
LS483446.1\|SQH70796.1\|23165_24332_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	2.13103e-133
LS483446.1\|SQH70800.1\|26717_29792_-\|CRISPR-associated-protein	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	1.46841e-158
LS483446.1\|SQH70801.1\|30140_30731_-\|outer-membrane-protein	gnl\|CDD\|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	6.17182e-06
LS483446.1\|SQH70806.1\|33745_34489_+\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|236281	PRK08517, PRK08517, 3'-5' exonuclease.	5.84199e-97
LS483446.1\|SQH70792.1\|13576_15103_-\|TpsB-transporter	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	1.33963e-54
LS483446.1\|SQH70793.1\|15282_21573_-\|haemagglutinin	gnl\|CDD\|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	2.61443e-23
LS483446.1\|SQH70799.1\|25798_26725_-\|CRISPR-associated-protein	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.97439e-99

>LS483446.1|SQH70796.1|23165_24332_-|cyclopropane-fatty-acyl-phospholipid-synthase
MFQKFLIKQVLKKWNFGRYVIEFWDGEQVKIGEGEPDFKITLKKPFGLNAFSQDLSLFFGEAYMDGNIEIEGDFDAISYVMYQFNNHHHLNKHKHITSKIHTKQESKNIKSHYDLGNDFYKLWLDPTKSYSCAYFKNPTDDLHQAQINKIEHTLKKLDLKKGEKLLEIGCGWGWLSIMAAQKYGVEVVGITLSEEQHKEATQRVKDCGLEDKVTIMLKNYQDLEMENYFDKAVSIGMFEHVGRANFPLYFSKVKQCLKPSGSFLLHTILASFEGETNAWIDKYIFPGGYLPSLRELISIASEFDFHLLLAESLRLHYAKTLDIWRENFEKEIEEVRKMYDERFIRMWRLYLKSCASAFRVGSADIFQFLLTKGVDNNIAMTHARIYQD
>LS483446.1|SQH70795.1|22618_23017_-|Uncharacterised-protein
MDLEVCRNPFCRRKSHTHDRVITNKRQMIQGQKRGDINQGNPTRCNAGCFLSRNASNKPKTLKIHYRFDKAGNLLVETPKTLGRVGVEFQSHSLAWLGCKCKLPRTCLKPLKALLHPSRLCFFAIFYSNACK
>LS483446.1|SQH70794.1|21612_22329_-|outer-membrane-protein
MIQSSGSISYKGTFQGVTQELHGSAFYKMDSSKNFGPLVSVNLGTEHLFFQDIFGFRWSIGVGYQSLAIKDRILPTFPDPQLNAYNTAIKTLEGPRFDASFDLMLNFFRNEKFSFGMFGGIQYNLYLAKFATKDSDFSKASIKITNDAFSLDLKTQGFNGQNTFGNAAYRVGLSMMFAKHHRVEFYISRNIASNSYKRNNERKNIYRQGNLEEKQVFKISEMLKLGTNTYMLSYKYVF
>LS483446.1|SQH70793.1|15282_21573_-|haemagglutinin
MRKIKQSLALLNALCLLGSSAIANPITIDTDHTGPSPTLGKTDNGVDLINIAKPNQAGISSNFYKDFNVEKEGLILNNISQKEDLAKTVLAGYIAANPNLETAAKLILNQVSGNKLSNLLGFLEVAGKQADVILANPNGITCHGCGFINIENLTLATGKFSQDEFHRLNQLKAYEELKTLSLDITQGKIITSALNASNTKTLTFLAKNMEVNGIVEGGDKIRALLGSNHVNFSPSVLLYEPIKLEGEQQALGLDVTYLGGVFAKSIYLVATNEGIGVKNSGILASTASQNSGDGGFVIDANGTIEITKPQTALIKQIQATKDPQNEGEKAPAPSALPLIFSNQNLDISAKNLVNHSILYAKDNLNIKAENILNQGALEFIQNPATREKFYSRDPNINGYFGGSKTYYMTYDYTIKTIKESIQKDTYSPAMMLANNIHLQSQTTTNDNALIQANNDFQNASKEFINKAPQAKSTTSYEGTKTLYNRYGKCFAGVKIGFNCASTRTTSAFVRADKVEFTDVELPEITLQDTSILLQDTLQNTKSSTPLPTPYVQNKDVLDLLVARRMQDAPSTRRDIMDFSIFQGSYQKNLLLGLQAHSIVISSQNTYNSSAITGNDITITSQALLNENGTLLARDTLKLKGEAITNQGGKILAQNISIDADGFTHTSSITSHKKDRIVSTNVSPLIAAVPVSKSYSEVFMKLAGRSYSKTVVIKKKNEELSSTSENTNLASLGILEGNHIIIKSKETHLIGANVDAKGDLLIQSDALSVKTLALKDNYADVVNTRNHTNQQVTSIQSGSDIVINSKQTNLISANIDAKGDLLIQSDTLNVKTLALKDNYADAVNTRNHTNQQVTSIQSGNHLLIDAKKQEYASVKMKGDTIALTGENILFDTSVNKSENKKLTRGILSPKLSTAPTTQHIANEIQGINLAIHSKSDFTAYNFDADITDSLSLKSDANLLISNHADSIQSPRNNTNKYSTQIDKSIAQTAKSIKLESKNIALIGANVDAKGDLLIQSDTLNVKTLALKDDYSDGTNIRNHTNQQVTSIQSGNHLLIDAKKQEYASVKMKGENIALQGENIRFDTSTLFDASTKESFSKGKKFDIKSFFLRPLVLETTTQHIANEIQGTNLAIHSKSDFTAYNLQTDSQNLAIQSDKNILISNHADSIQSTQDNINKYSTQIDKSIAQTAKNIKLESKNIALIGANVDAKGDLLIQSDTLNVKTLALKDDYADAVNTRNHTNQQVTSIQSGNHLLIDANKQEYTSVKMKGENIALQGENILFDTSTKESFSKTREKKTSGWFLDGKTTITTTTASTSQHIANEIQGSNLAIHSKNDFTAYNLQTDSQNLAIQSDKNILISNHADTKNVVVDTEIKKRSLYGSISKDKISAGLRTSNTKIHQDTNDKNHHNTTLKANHASFVAQGNTAIQSTNIQSDDLALQGESIALKALQDEHTSLETKHVTSHTFGVTINRRPLERLVIKYANSLGSKLGIKESIKVPEKEDIKAGFSYQYSDDFTKTQSYATSTSNLAIQSKNLQMDSKNDTVITNADITTDVFAAKNKNLAINTLENVKTTTTTKYNDTINASLKLSLGKQTGIKAHADYAHDGSKEKNTETSHVANHFKIGTLNLDTKNDVKIQGANLDIKEDANITAKNFALSSVSNTETNEKTDKKHNAALDFTYNGGFNVALSGGYGDSSSKENKVTQVASSLSAKNLNLKTSEKTQILGSRLNIEEDANITAKSFIITSTENSFAKTTHSKDANASLSAGFDGSLDLGANGGYTQKVTTQSNNSALSSDVSIKNLNLQSEDTKILGSNLTTKKAQITSKSLWIGSIQTYSKDTESSLGAQAGLGNKSGVKTAWDYNNKAQNSTGQTASHVSLGDFQIEVRGDTQIKGSHLSGDNGSIQTQNLNVLSSEETQKSHNIGLGAGNTNLKFRGNASLDLHTQTTQSASSIEAQNLKLAVKNDMNVESSQIKSENLDAKIGKNLNMVSKKDTEASFGVSGSLDMATKKKDFGIKGSIASQVKQQSSIEASNANIKVGNQTKLVGAKIEAKKGSFDGEKVSKESLIDYKVSLDKKSGKKLQKDFGHGITKSHISIN
>LS483446.1|SQH70792.1|13576_15103_-|TpsB-transporter
MRIRFYFFIIFFLGEAQAKDLCFLVKEITLSPLENTLENQKAFKKYFGFGEKIAKAYTNQCLNEKSINKLLQELNEKTIKKGFLTSKFGILPQDLKSQRLEIKLDIGRIHQITYNHNNLFFSFKKDFDIKEGDVLDLQKLQAGMANLKKMTHIDATMKILPSDQKNASDIVIHVEKKSFPFSGVYIFDNGNLKFLYQHTLLLAWENPLKLSDKLQSYLLASFFHDERIHKNYSIYHSLSYGVPFQQFFFEQNLAYSFNSFQIKLANFSPVYTGYSINTDTRMSYVFLRTQEHSLSFGLNFGARISKNFLENVLLVTQNRKVLLYSFFLRYALSLPTLQFNVDFSGLYGHSLANEFLHAYDYFIPVVNLYLYRPFKFFGRSLIYTGAIKTQVGSNKLYANDAFIIGGRYTVRGFDRLNYSGQMGVLCRNDLNLYIPFLKKFQLVPSIGFDVGYVKDLMSKDDIALSGGGLGIQWIQKYLNLQAWWYFAMFSSKSSVPKQNFFFSIAFNW
>LS483446.1|SQH70791.1|12722_13484_-|outer-membrane-protein
MMRKIFFPILFGFLLISTKLFAKEDIEFFIGADYGRMAHIKNSAKFKGGQNIYNFDDPLYGHLFLGSFGVEMGIGNTEILRKIFRSRVFIEGGYGKFGTNQGYELAGGLPNVKIKSLENYYVGGGADMMLNIIPFSYFSLGVFLGMGYDFVISDLSTKGSFLGSKASDYSGAQIYLSGFDGRFFHNEIYGRLGASIRFLKTQRIEFIVRIPAIENQGFAKIHRTLNKSNGEVYAKEKLLITTPTWLISYKIIF
>LS483446.1|SQH70790.1|12013_12712_-|outer-membrane-protein
MKKFLAIFFILLSSTYAKGSFLFGAGTDYIYEKTKYDSSGQKAQDWDVFATTRQEINGLKANINIGYEYLFFDIIGFRPMITLGYGALFSSKDNIVDRKPRNSLSLDSSYILSARAWLDLLINFPIPAQNLEVGFFVGGGAGIGYGNSTFKEKDLNSLETIHSFSEKTSLKQFLTRLGITFKINSQHRVDLFVIAPVYSIIDIKNSRYGEIHIRERNEFFPNSGGLNYYFLF
>LS483446.1|SQH70789.1|11176_12004_-|pyridoxal-phosphate-biosynthetic-protein
MHLGLNIDHIATLREARKINDPNPLEAIFIAKNCGVFQITIHLREDRRHIHDLDVKRILQSSFLPINVECALDENIIEFLCAQKPYKITLVPEKREEVTTEGGLSLKNPLIKDVIKTFHQHGILVATFVDPDEEAILLSKEYGADGVELHTGAYANATLMRYSNLSRMQNSIVSLQNLSSKDLNSLIKQNLKSLHFASVLAHKIGLEVYAGHGLNYHNVEAIAKLPHITELNIGQSIIAKSVFVGLERAILDMIQIITTTKNQTTLLNNTKKNPL
>LS483446.1|SQH70788.1|10241_11180_-|pyridoxal-phosphate-biosynthetic-protein
MRKKPKVAISIGDSNGIGGEILLSAHQKISQYCMPIYCAKRELLDSMAEILHALPLPKNTSFSAPTAPLPEINPGSIASDSGLYSFESFGLACSLADHKEVDFLTTLPIHKYAWKKAGIPFIGHTEYLRERYKSEGIMMLGCEKMFVALFSDHIPLRDVSNHLTTQKLSTFLLDFFACTHFSPIAVLGLNPHCGDNGLIGKEDSMIAQSILSANKILNREIFFGPFSADSAFAPLMRERFSTFVALYHDVGLAPLKALHFYESINVTLNIPILRTSVDHGVGFDIAYQNKADTRSYINAILLGNQLKHNKAE
>LS483446.1|SQH70787.1|9614_10226_-|Uncharacterised-protein
MKKKDYEKIISDQKYYIQVLESTLNRAYVELADKKNLFEQTNQKIEKLHNDIDDLLYFIIHQNNENHKNTPISLQEYFRSFSIKGGKNLIFGIHIEQKFIKNSSIPTLQYHLYKNHCFIQKKYSFFGLVSKNKRDLHFIGKTFCQYLEFCFKQASESIIGIITLSLQEEEILIDYYGNRDIEREFQDFIKLYTKEESLENLFT
>LS483446.1|SQH70798.1|25512_25836_-|CRISPR-associated-proteins
MEEKFMRVLVMFDMPTKSKEDRKASAKFRSTLLKEGYFMLQFSVYVRICKGVKSANTYLERLHLYLPKKGHIRALILTEKQFDHMKILIGEISQAQKVQKPTPLTLF
>LS483446.1|SQH70799.1|25798_26725_-|CRISPR-associated-protein
MFDEAFRTLFMSKPAKLSHKNNNLIIHGKEDIGIPLRDIHTIVIDTPQITLTSSLMKELAQYKILVFFCDDSHLPSGVFSPFLAHYRSSAILDLQIHFSKQNKSILWQKIIQAKIQNQTNLLMQENKTSTATKLQALQKAVKLADGTNNEAKASALYFPSLFGRGFSRKDFSPINAALNYGYAIIRGCIARNLVGSGLIPSLGIFHSNQFNPFNLADDLIEPYRPFVDSRVLALRIENELTLSHRVELVNLLNTKVLLQGKFYPFHRSITRMVWSISNFICDRGKMIELPILDKESNGREVYESFSDV
>LS483446.1|SQH70800.1|26717_29792_-|CRISPR-associated-protein
MIRTLGIDIGIASIGWAVIEGEYTDKGLENKEIVASGVRVFTKAENPKNKESLALPRTLARSARRRNARKKGRIQQVKHYLSKALGLDLECFVQGEKLATLFQTSKDFLSPWELRERALYRVLDKEELARVILHIAKRRGYDDITYGVEDNDSGKIKKAIAENSKRIKEEQCKTIGEMMYKLYFQKSLNVRNKKESYNRCVGRSELREELKTIFQIQQELKSPWVNEELIYKLLGNPDAQSKQEREGLIFYQRPLKGFGDKIGKCSHIKKGENSPYRACKHAPSAEEFVALTKSINFLKNLTNRHGLCFSQEDMCVYLGKILQEAQKNEKGLTYSKLKLLLDLPSDFEFLGLDYSGKNPEKAVFLSLPSTFKLNKITQDRKTQDKIANILGANKDWEAILKELESLQLSKEQIQTIKDAKLNFSKHINLSLEALYHLLPLMREGKRYDEGVEILQERGIFSKPQPKNRQLLPPLSELAKEESYFDIPNPVLRRALSEFRKVVNALLEKYGGFHYFHIELTRDVCKAKSARMQLEKINKKNKSENDAASQLLEVLGLPNTYNNRLKCKLWKQQEEYCLYSGEKITIDHLKDQRALQIDHAFPLSRSLDDSQSNKVLCLTSSNQEKSNKTPYEWLGSDEKKWDMYVGRVYSSNFSPSKKRKLTQKNFKERNEEDFLARNLVDTGYIGRVTKEYIKHSLSFLPLPDGKKEHIRIISGSMTSTMRSFWGVQEKNRDHHLHHAQDAIIIACIEPSMIQKYTTYLKDKETHRLKSHQKAQILREGDHKLSLRWPMSNFKDKIQESIQNIIPSHHVSHKVTGELHQETVRTKEFYYQAFGGEEGVKKALKFGKIREINQGIVDNGAMVRVDIFKSKDKGKFYAVPIYTYDFAIGKLPNKAIVQGKKNGIIKDWLEMDENYEFCFSLFKNDCIKIQTKEMQEAVLAIYKSTNSAKATIELEHLSKYALKNEDEEKMFTDTDKEKNKTMTRESCGIQGLKVFQKVKLSVLGEVLEHKPRNRQNIALKTTPKHV
>LS483446.1|SQH70801.1|30140_30731_-|outer-membrane-protein
MKKILLSLLLFLGMMHLAHARFFIGSNGGFGFGFGTKSIQNLVYSSELGYQFFFEPKERVGMRVFGQLGYNNLLTSDSVIATTQPALGLDMLFEGTKEDHFFAFGVFGGIQAGINSALPMSRKALARLAGLSPSDPVPLYRLNFLIKGRIGMSFIFVEHHRVEFFALIPIAPRSINAKRDYIPQTYNFMMGYKFVF
>LS483446.1|SQH70802.1|30918_32001_-|Uncharacterized-protein-conserved-in-archaea
MIWIDITDPKYVLFFRSLIPLLETIDSVVVTTRKSKDYEECYALLELFQIPSICVGNYGGNEIFDKLEARLKRQEGFLELFKRIGKPNLFITGVSVEGTQTAFGLGIPIIQFSDTPLASHRFELSKITVVAKLTLPLSSLIFRPFVVPEICYSALGVEPKNIIAYPFIDVALWLKDLPQGEDFRKRYHLPTTRPTILLREEEYKAHYVRTKLPIIYESIPLLNELDANLVIMPRYGSAELHRQFSSLKNLTILEEKLPPQDFYPFIDILIGGGGTMNLESCYLGIPTISTRSLFLFHDKYLLDHHLMQHHTDSQALYHQVKAWIAQETKRKNQREFFESSPANFQEIFAIIQERYYKHQK
>LS483446.1|SQH70803.1|31997_32198_-|Uncharacterised-protein
MSENPAKDTFALQLDRALQDLQKCQKERNYDSCLKCEKFFECPVRKSYVSAVYKSMNKGEQGGFEF
>LS483446.1|SQH70804.1|32194_33025_-|fructose-1,6-bisphosphatase
MQQIFDTLKHIALEIHALLQDSNTTYLESTNSTGDVQLQVDVIADKLIEERLLALPSVRGVASEEKPNAIEKAEGEFLIAYDPLDGSSLVDSNLSIGSIFGIYAQDFQGKNLIASAYIIYGPRTEIVFAHKNISYQSYNGKQWIQKPTPKLQTKGKISATGGTQKHWSKEHKALIESFFAAGYRLRYSGGMVPDLHQILIKGGGIFSYPATSDAPKGKLRKLFEVFPFAYIYELCGGEAIGENGVRLLDLPCAHLHDTTPCYFGSLEEIALFKEKK
>LS483446.1|SQH70805.1|33107_33746_+|ribulose-phosphate-3-epimerase
MLVAPSLLSANFMRLGEEIRALCDAGADFLHIDVMDGHFVPNLTFGPVVLEQIAKYASKPLDVHLMVENVSFFVELFAPLKPEFMSVHIEEVKHLHRVIESIRKHGIRPCVVLNPHSSEQDLKYILEDIDMVLLMSVNPGFGGQKFIPSVCKKAKMLHHRIQEYNPKCLIEVDGGVNEKNISLLKESMVDVVVAGSYIFNQSDYKKAVDSLR
>LS483446.1|SQH70806.1|33745_34489_+|DNA-polymerase-III-subunit-epsilon
MYKKVYAKFQKDSIEREKFFPYMGEILGVFDEDLILELLRDCGLWIEESGDRLELGTLQKDIKDGVFCFVDIETTGSKPNHSSIIEIGAIKYHGGEIIDTFETLVFSQSVPENITELTGIDAGMLADAPSEREVLQRFRKFLGNSVFVAHNVVFDYGFISDRLLRYNEPYLLNPRLCTVELARRGILSARYSLGHLNAFLGIGIDKQHRALSDAFICLKVFEIAQLTLPNHVQNIQGLIEYTRGKKL
>LS483446.1|SQH70807.1|34775_35033_-|Uncharacterised-protein
MADVNITPESIMEKLKEKGAKLSCPSCHGKDIGIAPGFTNILLQNKIDGSLSVNGPHVPAIYTVCNKCGSMNPHAVAVLGILNQQ

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Crispr_ID: LS483446_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LS483446_2

559867-559956

Orphan

Consensus_repeat	Method
ATTGTGATTTTATGTTTTTATCCTTAAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LS483446_2

>merge|LS483446|2|559867-559956|CRISPRCasFinder
ATTGTGATTTTATGTTTTTATCCTTAAACTCAAGAAAATGATATTAAAGAATGGTTTTTTATTGTGATTTTATGTTTTTATCCTTAAACT

>LS483446|2|2|559867-559956|CRISPRCasFinder
ATTGTGATTTTATGTTTTTATCCTTAAACT	CAAGAAAATGATATTAAAGAATGGTTTTTT
ATTGTGATTTTATGTTTTTATCCTTAAACT

Protein	Signature genes	Signature genes Name	Protein_function
LS483446.1\|SQH71253.1\|548429_549572_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|223758
LS483446.1\|SQH71263.1\|567044_567671_-\|7-KHG/KDPG-aldolase	unknown	unknown	gnl\|CDD\|235577
LS483446.1\|SQH71262.1\|564172_566872_-\|outer-membrane-protein	unknown	unknown	gnl\|CDD\|280099
LS483446.1\|SQH71249.1\|543372_544131_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH71267.1\|571216_571897_+\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|273494
LS483446.1\|SQH71266.1\|570978_571167_+\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH71252.1\|546785_548219_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223903
LS483446.1\|SQH71268.1\|571877_572882_+\|glucokinase	unknown	unknown	gnl\|CDD\|234716
LS483446.1\|SQH71259.1\|559996_561553_+\|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223651
LS483446.1\|SQH71261.1\|563060_563792_+\|glycerol-uptake-facilitator-protein	unknown	unknown	gnl\|CDD\|223653
LS483446.1\|SQH71251.1\|545809_546763_-\|arginase	unknown	unknown	gnl\|CDD\|162262
LS483446.1\|SQH71265.1\|569603_571010_+\|glucose-6-phosphate-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235579
LS483446.1\|SQH71260.1\|561562_563050_+\|glycerol-kinase	unknown	unknown	gnl\|CDD\|198361
LS483446.1\|SQH71254.1\|549950_550406_-\|H+-Antiporter-protein	unknown	unknown	unknown
LS483446.1\|SQH71258.1\|559100_559241_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH71257.1\|552330_552708_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH71255.1\|550548_551043_-\|Uncharacterised-protein	unknown	unknown	unknown
LS483446.1\|SQH71250.1\|544127_545057_+\|siderophore-mediated-iron-transport-protein	unknown	unknown	gnl\|CDD\|223880
LS483446.1\|SQH71256.1\|551058_552306_-\|ligase/carboxylase	unknown	unknown	gnl\|CDD\|235010
LS483446.1\|SQH71264.1\|567680_569483_-\|phosphogluconate-dehydratase	unknown	unknown	gnl\|CDD\|181628

Protein	Function_ID	Function_description	E-value
LS483446.1\|SQH71253.1\|548429_549572_+\|alanine-dehydrogenase	gnl\|CDD\|223758	COG0686, Ald, Alanine dehydrogenase [Amino acid transport and metabolism].	1.36532e-166
LS483446.1\|SQH71263.1\|567044_567671_-\|7-KHG/KDPG-aldolase	gnl\|CDD\|235577	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	1.87631e-103
LS483446.1\|SQH71262.1\|564172_566872_-\|outer-membrane-protein	gnl\|CDD\|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	0.000114791
LS483446.1\|SQH71250.1\|544127_545057_+\|siderophore-mediated-iron-transport-protein	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	3.36865e-16
LS483446.1\|SQH71268.1\|571877_572882_+\|glucokinase	gnl\|CDD\|234716	PRK00292, glk, glucokinase; Provisional.	2.0406e-176
LS483446.1\|SQH71259.1\|559996_561553_+\|glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	4.25988e-153
LS483446.1\|SQH71261.1\|563060_563792_+\|glycerol-uptake-facilitator-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	1.75843e-64
LS483446.1\|SQH71251.1\|545809_546763_-\|arginase	gnl\|CDD\|162262	TIGR01229, rocF_arginase, arginase. This model helps resolve arginases from known and putative agmatinases, formiminoglutamases, and other related proteins of unknown specifity. The pathway from arginine to the polyamine putrescine may procede by hydrolysis to remove urea (arginase) followed by decarboxylation (ornithine decarboxylase), or by decarboxylation first (arginine decarboxylase) followed by removal of urea (agmatinase).	2.4642e-98
LS483446.1\|SQH71265.1\|569603_571010_+\|glucose-6-phosphate-1-dehydrogenase	gnl\|CDD\|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
LS483446.1\|SQH71260.1\|561562_563050_+\|glycerol-kinase	gnl\|CDD\|198361	cd07786, FGGY_EcGK_like, Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases. This subgroup is composed of mostly bacterial and archaeal glycerol kinases (GK), including the well characterized proteins from Escherichia coli (EcGK), Thermococcus kodakaraensis (TkGK), and Enterococcus casseliflavus (EnGK). GKs contain two large domains separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The high affinity ATP binding site of EcGK is created only by a substrate-induced conformational change, which is initiated by protein-protein interactions through complex formation with enzyme IIAGlc (also known as IIIGlc), the glucose-specific phosphocarrier protein of the phosphotransferase system (PTS). EcGK exists in a dimer-tetramer equilibrium. IIAGlc binds to both EcGK dimer and tetramer, and inhibits the uptake and subsequent metabolism of glycerol and maltose. Another well-known allosteric regulator of EcGK is fructose 1,6-bisphosphate (FBP), which binds to the EcGK tetramer and plays an essential role in the stabilization of the inactive tetrameric form. EcGK requires Mg2+ for its enzymatic activity. Members in this subgroup belong to the FGGY family of carbohydrate kinases.	0
LS483446.1\|SQH71267.1\|571216_571897_+\|6-phosphogluconolactonase	gnl\|CDD\|273494	TIGR01198, 6-phosphogluconolactonase_6PGL., 6-phosphogluconolactonase. This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway].	7.92706e-54
LS483446.1\|SQH71252.1\|546785_548219_-\|amino-acid-permease	gnl\|CDD\|223903	COG0833, LysP, Amino acid transporters [Amino acid transport and metabolism].	2.71583e-160
LS483446.1\|SQH71256.1\|551058_552306_-\|ligase/carboxylase	gnl\|CDD\|235010	PRK02186, PRK02186, argininosuccinate lyase; Provisional.	6.06247e-28
LS483446.1\|SQH71264.1\|567680_569483_-\|phosphogluconate-dehydratase	gnl\|CDD\|181628	PRK09054, PRK09054, phosphogluconate dehydratase; Validated.	0

>LS483446.1|SQH71258.1|559100_559241_-|Uncharacterised-protein
MFNWEDPPFFFLGSIKNKGTKRNYKERTKGNIKLNKERINKSRFKK
>LS483446.1|SQH71257.1|552330_552708_-|Uncharacterised-protein
MLADRGIIWRMMNKEFTNCVRDLLAMKKNRVFHSYDWSDVSAVPTIICQLYIIEFLLSMERNKLSKAKSIYLKIKKDVLLDGYSRLLDGVIKGLFQSKYRKTRRLILSFLRANPADIYLFYVCHI
>LS483446.1|SQH71256.1|551058_552306_-|ligase/carboxylase
MSIQSFIVLLGANQYLRERALKGAREVSDALIFIADKNAKFNKNRYFDGALQADSNDAQSLIQCIQEKQSLGFKLLSVIPLNDWVLKSANEINAFFHLPHLSLEVIENARNKYKMKCKFKEHGVPSSPFFLLEHEEELAKAIEVIGFPMIIKPYDFGGSGGVYLARNPKEASEKLALSKAIIAQYKNAFKIAGDKYLIEKYIDTQEEVSVEVLCFKDKCITLSVTEKYLSPKPYFSEMAHLVPSHRNLDKKLNEIAHNAALCLGIDKGLAHVEIKILKDSYWVIEVGARTGGDGILDQVERAFGVNPYALHIASYLGRDLSGFQMPEPKGSAFIGFLKAKEGKIQKIHYPLIDDLPKELESIKITAKEGDIAMPPKDWSAREGVMEFYYPHQFFKEKTNLPLELLQQWSEKIFES
>LS483446.1|SQH71255.1|550548_551043_-|Uncharacterised-protein
MKGYIFISGLYRLSCGALILAVNWMMAIQGPSFGSLALLVTLTFLPAAFVPLVWKKPLEGHKTTAYALICCGILSFCLYYFHHHNVVVLFNTFLWFFFFILESSWESWFASLSKSHTPQEIDKYSSLSMSVNQASLMIGPIFAAFLFKNTPKEVIFWLWDSFHP
>LS483446.1|SQH71254.1|549950_550406_-|H+-Antiporter-protein
MLPAQIAYSKGEMTDVGILDAAMGLGMILSSFLLSFKNAKKIFIHYYLSVGIIILGIVCWFFAQNILLKILSLLCLGASFNLIRISIRSFIAQEYDSQNAGRIVSYANSLAFFVIILLLSLSYDALLIHWLLPFLLTALLCVMFSLVIRNQ
>LS483446.1|SQH71253.1|548429_549572_+|alanine-dehydrogenase
MDMGLIKESMDLESRVALVPDDVALLTQRNVNVVVEDGAGENSGYSNAMYEAAGAKIVDTKSAWEQDVVVKCKEPLEHEYSLPREGATLFSYLDLAYQKSLCEMLIEKKITSICTETIAGARNDYPILMPMSVVAGRLAAHLLQHYLLALEHVEGFWGKGVMLGGLSGVQRSKVVVVGGGVVGMESAKMLSQMGARVSVLELDYIKLQTHPYCSMYDLEILSVNEANIINALDGAVGLVGAVLLTASQTPKVILRRHLRYMQKQGVVIDVACDLGGCIETIHQTNHSNPVYVEEGLLHYGVPNMPGIVAKTSSIAYSNASVPYLLYYVEHGLKGFLQANTKIVANTLGGLSAHNGYITQEGIARAFNLAFKSPLEVLKEL
>LS483446.1|SQH71252.1|546785_548219_-|amino-acid-permease
MRDTTSTELSRDINMRQLMMIALGGTIGTGLFVGTGGNIASAGPLATLLAYLIGGIIVYSIVLSLGELSSVYPTTGSFGDYASRFIGPSTGYMVFWMYWLSWVLTVAVEYIAIGLLMQRWFPDIPVYVWVIACIMLLFLLNFFSVKIFAMGEFLLSAIKVLAVFVFIVLGGIGIIYSFYLHGFDGVFGNFYFNGETQGLQKGLFPKGVGAFFGVILAVIFAYTGTEIIGVAAGETKDPSKIMPKAIKATLWRIIFFFLGAVFVVSVFLPMTDSGLSQSPFVSTLEKIPLPFFGVGIPYAADIMNFVIITAILSTANSGLYASGRMIYGLSQKKMFFPIFTKLNSSGTPTYALYLSLGITLVGMLTEAFAPEKIMASLINVVSFMVIIVWISISVAQYFFRREYLASGRLLKDLPYKTPFNPLIQIIGISGCLVGLIGAYMDESERIGGYLTLVFMGLCYVAYYLSKDKWGFKEEKGL
>LS483446.1|SQH71251.1|545809_546763_-|arginase
MILVGLEAQLGASKQGSDEGVKALIEALRPKHGELVRHMHRIAQERCILDKKFRYARSFEDYYVFCKEILIPRMQEVFLRKEFSLILSSEHANMFGIFQALRSVHKDKKIGILYLDAHADIHTAYDSDSRYIHGMPLGMVLNRVRSGFNCMNQSEEEAWQELCNLGLEKGTLEIDPRHLVYFGVRSTEQSERDVIKELQIPLFGIDSIRENMQEVVEQSKILLRDVDIIYLSLDLDIMDGKLFTSTGVRENHGLSFKELREFLQLLLEGFKDRLSAVEVTEYNPLVGLKNEEKEVLEILKEIIRICKDSSWGASLGD
>LS483446.1|SQH71250.1|544127_545057_+|siderophore-mediated-iron-transport-protein
MKVKDNQRFFYAFLLSLLLHALIIALVMLINHYQPAPPRLQKVKLDNLLVLKRGQSQDPTKNTKGARKPSLAAKPTAPSRPTPRPTPKPTPSPRIAAANPMPKPREVPKPQEPQKQEKPKKPEEKPKEQEKPQEKKQVDSKRKALDTYEQTPIDPKNLSFIGQNDSDDPMMNMDSGGGGGGNPSEQDDKGSDPETAQEIDDLYGEEFGDLGTAEKDFIRDNLRNIGRITQKYLQYPRVAAYFGQSGVNAVEFYLHPNGDISDLKIIRSSGLNSFDNNTLNTIQIAYKDYPRPKVKTLIRINVTYSYYGN
>LS483446.1|SQH71249.1|543372_544131_+|Uncharacterised-protein
MRKITLLLFLYLGMVYGVSIEEIQAKSDAGYNDVFLTFPSPLKQKIKLLYDEKKEIYFIQGLSSPKPFFQRFSKGALDSIMIYADGNVLYLSMKPSSNQGFSIDLALSRDKKSLRLRFAPLQSLANQSQELARKSLANKSIESLAAPKTSEIKPASMQSFSNQEVGVGTWQYNLVMIFLLLLIIAFLLAQKKIRKNRGRGSLPFVQNYPIDSKNRIISIGMKDRSYLIFEGSKGYVLLEKIKPKEKRVIQKS
>LS483446.1|SQH71259.1|559996_561553_+|glycerol-3-phosphate-dehydrogenase
MDRMQEYNKLKETSLWDVVIIGGGATGLGIALDSALRGYKTLLCEALDFAQGTSSRSTKLLHGGVRYLAQGEISLVYEALHERDRVIRNAPHLCKKQAFIIPNTSFFDACFYTFGLKIYDFIAGAFGIGKTSYLSANKARSRLRGIKEHKISSGVCYYDGQFDDARLALNLAQSAAREGACVLNYARVESLLKNQDGEIEGVGIRLQDTQEILEVHSRCVINASGVFGDGINAMDHARGNSIAPSQGIHLVFDKSFLPGNDALMIPKTPDGRVLFAIPWYDKVVVGTTDTLVNDICYEPSALDEEIAFILNTFGEYATKTPGRDDVLSVFAGLRPLVKQDQSASTKDISRKHKISLSPSKLITINGGKWTTYRRMAQDCLDFIIKHQLLPKSPCKTQDYKIYGYKEDGDPADRLHMYGDKAEEIYRLEEQDPRLKKPIHKDYSYTFAQIFWALEHEMAQHLDDVLARRIRLLFLDARAARACAKDVAHFMAEHLAWSQSRLESEIESFMKLSERYYLK
>LS483446.1|SQH71260.1|561562_563050_+|glycerol-kinase
MKRYIMAIDQGTTSSRTIIFDKMGNVISSAQKTISQIFPQSGWVEHDAKEIWASQISTLTGALAKANISASEIAAIGITNQRESTVIWDRESGEPIANAIVWQDRRTADYCESLKEKYAKSIHQKTGLIIDAYFSATKIKWLLDNIPNARKKAENGQLCFGTIDTWLIYNFTGGKVHVTDPSNASRTMLYNIHTLQWDDELLELFDIPKKLLPEVRSSSEIYGHTMTRWVDSQIPIAGVAGDQQSALFGQMCIEKGAMKNTYGTGCFLLMNTGDKPVMSQNNLLTTVAWQIQDRVSYALEGGVFVGGAAIQWLRDGARMIRTAADINTLAATVEDNGGVYFVPALTGLGAPYWDQYARGTFFGISRGTTDGHIARAVLEGIAFEVYDIVKEMEKDLGEKCIELRVDGGASASDYLMQIQADIFGFNIVRPKTIETTALGAAYLAGLAVGFYKDIEEIKSQWHIDKTFSPKLEKERVQEMLHFWHKAVSSSLHWLS
>LS483446.1|SQH71261.1|563060_563792_+|glycerol-uptake-facilitator-protein
MSIFVSEFIGTGLMILLGNGVVATCVLKGTKCGDGGHWLIITTAWAFAVFVGVVVAGESSGAHLNPAVTLALALAHKLEWQLVPSYIAGEFLGAMFGALLVWIMYKQHFALTSDEGAKRACFCTSPAIRNYPSNFLSEAIGTFVLIFVILHLSGANIILGTDSTASIGLGSLGALPVAILVWVIGLSLGATTGYAINPARDLGPRIVLFLLPLKISADWGYAWIPICAPIVGGVVAVYLSNIL
>LS483446.1|SQH71262.1|564172_566872_-|outer-membrane-protein
MRRYLFPFIFGGLPLMAYNPKDGYFVEGGITTGMVETAETIIPPRSLLPSVPIPKRPPIKRISGTTPLIQSTQYSTQPIFTQDKLGSSTNQNPTPIILSAAHPIAIKLENGNVVIQNFLPYNLTNVDITMNTPGNKDRVIVGRIADLKPFEITTIPQTHMPEIAKVLAEYQQQEQQQQKQQQNRTLSGAQLAAAQNIQQSYIDKNNPNIDTRFLVDASSSSNAQTKHVLGIFERIWVDITAKFAPITPIPDLLKPNNGSWAWGVPTPYSAKLITYALENLAAVLSSPQFKQAVLHAPFAFVNGPGDYNPNVVPLSNGQAKPGSQKYVLSPETVYKQYTTSKNITVDIMSPSGYEGLGSPAVWGVQPGLINYYFKPDKSSKEKPPIYLSNDPLTPGTNIWPLITIWHEWGHVNGYSHNGDMTYQNGWFNNTDQAKPNNDAGAASAWDRFDKNPGDASGLPFVTNKNGTYFLAGMGGLGVGVWTYLGAHNELPINYKDLPAAEPNNRPNWSFNAPAWWTNPIVKPVAPIEPLAPPKESNGTENAENKKMYDAAMAQYQKNMKQYETDEANFKKRWDAYLKGLEDVQKNGTNFDSPVWYEAWAKQQAIKNKEELEKFYNEALKKAEQAVINQYNSYAGVTHITSLPANSTSAKQVAAASLNSATGAAQLAQLPQSNASNESGSGPGGGASAAQVPQSTPAQSATSEVSFRRLPREMSSYSSTFLSGLSSTLNSMSRVSNKSAMVGFNVMGGYQHYFNDTVGMSYYGIMKYNYAGVNKISASINQVGLGVGSNVLIDFYTKYTTIKEKDALEAIRRFDSSLGMFAGLRALWQGYGMLGRFVNAGNLNFTTGFNYRVGHSKYSLGISVPMISYDIKVATLGNREISIKEGPSHFNVFFNYGWVF
>LS483446.1|SQH71263.1|567044_567671_-|7-KHG/KDPG-aldolase
MQAREILQISKIIPVITIHDAKTSIDLARALVHGGIKILEITLRTKEALEAIKILSREVPEATVGAGTVLNAKMLEEVKHAGAKFAISPGLTPTFAKEAKNINLTLIPGVSTASELMLALEFGYKDLKFFPAEAAGGVGMLKSLAAPFHEVKFCPTGGISPDNINDYLHLENVLCVGGSWLSPKELILAKKWDEISQITRDSLAKITK
>LS483446.1|SQH71264.1|567680_569483_-|phosphogluconate-dehydratase
MKNKKLEQITQKVMERSQKTREAYLERIAGHKGKIQRKDLGCANLAHAYATIPSHIKDKIKENKDLNYAIISAYNDMLSAHQPFKNYPDLIKKEIFNHHAFAQFAGGTPAMCDGITQGYEGMELSLFSRDVIAMSVAIALSHNVFDGAFYLGVCDKIVPGLLIGALSFGHLPSIFVPSGPMASGISNDEKSKMRQLFAQGQISRDKLLESEMKSYHDVGTCTFYGTANSNQMMMEFMGLHLPNSAFIHPNTPLREALVKEAAAHMATSQIKPIGELLGEKNIINAMIGLMATGGSTNHTIHLIAIARAAGIIINWDDFDAISSIIPLLARVYPNGRADVNQFEASGGIAFIIHQLLKEGLLHDDVDTVMGQGMQPYTKNPFLIDGKLTYKDGVKTSKNTEILRDIENPFSKDGGVKILRGNIGRAVIKISAVKEEHQIIKAPALIFHSQQEFLQRFQNKELERDFIAVLPYQGPRANGMPELHKLTPPLGALQDQGFKVALITDGRMSGASGKVPAAIHMSPEALLGGSIAKIKEGDMIVLDAKNGVLEVLVDEKEWNQREAAIFTQKEIFGSGRELFAGFRAQSSSAETGAMSFGGYFQ
>LS483446.1|SQH71265.1|569603_571010_+|glucose-6-phosphate-1-dehydrogenase
MQQLKDFEFILFGATGDLAMRKIFPSLYGAYSKGLLSPKGRIIATGRSVLDLGQFLGELEKKSKIHIKNCDEKKWAEFTQNISYVSINLNKLADFKILKNSLDQRCDNRVIYFSISPQYFIKACEHLAQIGFNEKNVKIVLEKPLGMDLKSCQEINDAIAKYYKEEQIYRIDHYLGKEVIQNLLVLRACNPLFLSVWDREHIDCVEITIFEALGVEARGEFYDNTGALRDMLQNHILQILSLIAMKIPKVLDAPSIREAKLELLKKLKPFKKEEIKKQVIRAQYGKSAGFKAYLEEENIREHSQAETFVAIKAQIEDPMWLGVPFYLRTGKRMAESFGQIVISFKNKNLQGYTNKLIIFLQPDNHISLNLKTKKIGNSMDVEEKTLDLHLDDSAAMQPYEKLILDVIEGNQASFNHREELEAAWRWIDPILENWKNNESELYLYPAGSWGPKEALDLVYECSHEWHNC
>LS483446.1|SQH71266.1|570978_571167_+|Uncharacterised-protein
MSVLMSGIIVKPAAQSTRFFGVKMGKGFERMSVLISGVFSHFKLFNVKNRNSFVKFEKRFNF
>LS483446.1|SQH71267.1|571216_571897_+|6-phosphogluconolactonase
MAFRFYEFSNSQECNLSLVSWLGEFLTEKALLNGGASLAVSGGKSPVALFELLSREKIAWDKICISLVDERIVSLESEDSNTALVKSHLLQNSAKGASFIPILKDPSLSLELLLEFANKHYRQADLAILGMGLDGHTASLFPEASEFEHALESEQNIISTTPKNAPYQRLSMSLKALKKTKKLILTLKGEDKKKVFEEASLGVNPKLPISYILHSREVDCDVYYSK
>LS483446.1|SQH71268.1|571877_572882_+|glucokinase
MSITQNKGKELYPRLLADIGGTNARFALELSKSKIEHIEVLACNDYNTIVDAVKAYLSKVGNPVVNYGAFAIANPVVGDWVQMTNHHWAFSIETTRQALDLEVLILINDFTAQAHAISRMPLSELVQIGGNSCAIHAPKAVLGPGTGLGVSGLIPCLDSYIALAGEGGHTTFAPFDDTEVMIWQYAKKKFGHVSVERFLSGSGLCLIYEALSHREGMKNSKMTPELISEQALSGKFPLSRLTLDIFCAMLGTVASDLALTLGARGGVYLCGGIIPKIIEYFKNSPFRTRFENKGRFDAYLAAIPVYVVLAKYPGIHGVAVALENYLKDYFKNKG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LS483446_1	1.1\|24742\|29\|LS483446\|CRISPRCasFinder,CRT	24742-24770	29	MN940411	Staphylococcus phage f2b1, partial genome	98357-98385	6	0.793
LS483446_1	1.8\|25203\|30\|LS483446\|CRISPRCasFinder,CRT,PILER-CR	25203-25232	30	MN694636	Marine virus AFVG_250M782, complete genome	35107-35136	6	0.8
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP031070	Bacillus sp. JAS24-2 plasmid pl278, complete sequence	161397-161426	6	0.8
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NC_010113	Vibrio sp. 0908 plasmid p0908, complete sequence	13055-13084	6	0.8
LS483446_1	1.1\|24742\|29\|LS483446\|CRISPRCasFinder,CRT	24742-24770	29	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	304474-304502	7	0.759
LS483446_1	1.1\|24742\|29\|LS483446\|CRISPRCasFinder,CRT	24742-24770	29	KX171213	Staphylococcus phage vB_SscM-2, complete genome	133203-133231	7	0.759
LS483446_1	1.1\|24742\|29\|LS483446\|CRISPRCasFinder,CRT	24742-24770	29	NC_047767	Staphylococcus phage vB_SscM-1, complete genome	133202-133230	7	0.759
LS483446_1	1.9\|25269\|30\|LS483446\|CRISPRCasFinder,CRT,PILER-CR	25269-25298	30	NZ_CP044550	Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence	123767-123796	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP013333	Fusobacterium hwasookii ChDC F174 plasmid unnamed2, complete sequence	3796-3825	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP011152	Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence	141186-141215	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MH059636	Erwinia phage Cronus, complete genome	6822-6851	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP014284	Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence	245402-245431	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP032609	Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence	39243-39272	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP053953	Bacillus cereus strain FDAARGOS_798 plasmid unnamed2, complete sequence	315624-315653	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP011154	Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence	405700-405729	7	0.767
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP053950	Bacillus cereus strain FDAARGOS_799 plasmid unnamed2, complete sequence	209871-209900	7	0.767
LS483446_1	1.2\|24807\|30\|LS483446\|CRISPRCasFinder,CRT	24807-24836	30	MN855765	Myoviridae sp. isolate 14, complete genome	9457-9486	8	0.733
LS483446_1	1.6\|25071\|30\|LS483446\|CRISPRCasFinder,CRT,PILER-CR	25071-25100	30	NC_008376	Geobacillus phage GBSV1, complete genome	10713-10742	8	0.733
LS483446_1	1.6\|25071\|30\|LS483446\|CRISPRCasFinder,CRT,PILER-CR	25071-25100	30	NC_009737	Bacillus virus 1, complete genome	10710-10739	8	0.733
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP011404	Lactobacillus salivarius str. Ren plasmid pR1, complete sequence	14883-14912	8	0.733
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NC_010697	Erwinia tasmaniensis Et1/99 plasmid pET49, complete sequence	13915-13944	8	0.733
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP017108	Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence	170871-170900	8	0.733
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	85780-85809	8	0.733
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP015177	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB267, complete sequence	525-554	8	0.733
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP010090	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence	170456-170485	8	0.733
LS483446_1	1.4\|24939\|30\|LS483446\|CRISPRCasFinder,CRT,PILER-CR	24939-24968	30	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	420159-420188	9	0.7
LS483446_1	1.5\|25005\|30\|LS483446\|CRISPRCasFinder,CRT,PILER-CR	25005-25034	30	KU594605	Cyanophage S-RIM50 isolate RW_29_0704, complete genome	28918-28947	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	CP041517	Bacillus aryabhattai strain KNU10 plasmid unnamed1, complete sequence	8647-8676	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250021	Prevotella phage Lak-B2, complete genome	549521-549550	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250024	Prevotella phage Lak-B5, complete genome	543211-543240	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250028	Prevotella phage Lak-B9, complete genome	549735-549764	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250023	Prevotella phage Lak-B4, complete genome	550234-550263	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250025	Prevotella phage Lak-B6, complete genome	546338-546367	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250022	Prevotella phage Lak-B3, complete genome	546428-546457	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250027	Prevotella phage Lak-B8, complete genome	551354-551383	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MK250020	Prevotella phage Lak-B1, complete genome	547653-547682	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NC_049978	IAS virus, complete genome	35804-35833	9	0.7
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NZ_CP013122	Fusobacterium nucleatum subsp. polymorphum strain ChDC F306 plasmid unnamed1, complete sequence	13526-13555	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NC_021277	Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence	13497-13526	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	KX160205	Lactococcus phage 49801, complete genome	14189-14218	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	KX160212	Lactococcus phage 98101, complete genome	13189-13218	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	MN693456	Marine virus AFVG_25M411, complete genome	8521-8550	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	AF323670	Bacteriophage bIL309, complete genome	12750-12779	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	AF323669	Bacteriophage bIL286, complete genome	14778-14807	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NC_002668	Lactococcus prophage bIL309, complete genome	12750-12779	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	KX160218	Lactococcus phage 98204, complete genome	15585-15614	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	NC_002667	Lactococcus prophage bIL286, complete genome	14778-14807	10	0.667
LS483446_2	2.1\|559897\|30\|LS483446\|CRISPRCasFinder	559897-559926	30	KX160213	Lactococcus phage 98102, complete genome	13119-13148	10	0.667

1. spacer 1.1|24742|29|LS483446|CRISPRCasFinder,CRT matches to MN940411 (Staphylococcus phage f2b1, partial genome) position: , mismatch: 6, identity: 0.793

tagagttagtagttctctttttctttcct	CRISPR spacer
gagagttagtagctctccttttcttttaa	Protospacer
 ***********.****.********.

2. spacer 1.8|25203|30|LS483446|CRISPRCasFinder,CRT,PILER-CR matches to MN694636 (Marine virus AFVG_250M782, complete genome) position: , mismatch: 6, identity: 0.8

tcgtagcgttatctttcccatgcacagcat	CRISPR spacer
acggagcgttatctttaccatgcacatcga	Protospacer
 ** ************ ********* *.

3. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP031070 (Bacillus sp. JAS24-2 plasmid pl278, complete sequence) position: , mismatch: 6, identity: 0.8

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgatattaaagaataccttata	Protospacer
 *********************. .** *

4. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NC_010113 (Vibrio sp. 0908 plasmid p0908, complete sequence) position: , mismatch: 6, identity: 0.8

caagaaaatgatattaaagaatggtttttt---	CRISPR spacer
taagacaatgatattaaagaa---tttttcagg	Protospacer
.**** ***************   *****.

5. spacer 1.1|24742|29|LS483446|CRISPRCasFinder,CRT matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

tagagttagtagttctctttttctttcct	CRISPR spacer
ggcgattactagtactctttttctttcct	Protospacer
 . ..*** **** ***************

6. spacer 1.1|24742|29|LS483446|CRISPRCasFinder,CRT matches to KX171213 (Staphylococcus phage vB_SscM-2, complete genome) position: , mismatch: 7, identity: 0.759

tagagttagtagttctctttttctttcct	CRISPR spacer
tctctctagtagttctctttctctttctt	Protospacer
*    .**************.******.*

7. spacer 1.1|24742|29|LS483446|CRISPRCasFinder,CRT matches to NC_047767 (Staphylococcus phage vB_SscM-1, complete genome) position: , mismatch: 7, identity: 0.759

tagagttagtagttctctttttctttcct	CRISPR spacer
tctctctagtagttctctttctctttctt	Protospacer
*    .**************.******.*

8. spacer 1.9|25269|30|LS483446|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044550 (Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence) position: , mismatch: 7, identity: 0.767

tgatgcagttgcaacacgtagaaagagtct	CRISPR spacer
tgatgcagttgcacctcgtagaagtcttcg	Protospacer
************* * *******.   **

9. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP013333 (Fusobacterium hwasookii ChDC F174 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
taagaaaataaaattaaagaatggtaatga	Protospacer
.********.* *************  *

10. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP011152 (Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgaaattaaagaataccttata	Protospacer
 ********** **********. .** *

11. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MH059636 (Erwinia phage Cronus, complete genome) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagagaatgatgttaaagaatgggattca	Protospacer
 ****.******.***********  **.

12. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP014284 (Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgaaattaaagaataccttata	Protospacer
 ********** **********. .** *

13. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP032609 (Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgaaattaaagaataccttata	Protospacer
 ********** **********. .** *

14. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP053953 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgaaattaaagaataccttata	Protospacer
 ********** **********. .** *

15. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP011154 (Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgaaattaaagaataccttata	Protospacer
 ********** **********. .** *

16. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP053950 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aaagaaaatgaaattaaagaataccttata	Protospacer
 ********** **********. .** *

17. spacer 1.2|24807|30|LS483446|CRISPRCasFinder,CRT matches to MN855765 (Myoviridae sp. isolate 14, complete genome) position: , mismatch: 8, identity: 0.733

tgagctatacggattgcaaagattcttttt	CRISPR spacer
cataatatactgattgcaaggattctttat	Protospacer
.. . ***** ********.******** *

18. spacer 1.6|25071|30|LS483446|CRISPRCasFinder,CRT,PILER-CR matches to NC_008376 (Geobacillus phage GBSV1, complete genome) position: , mismatch: 8, identity: 0.733

tcaacgcctgcaatattgtaattaatcttc	CRISPR spacer
tcaacgcttgcaatattgtaaaaagattct	Protospacer
*******.*************  *. .*..

19. spacer 1.6|25071|30|LS483446|CRISPRCasFinder,CRT,PILER-CR matches to NC_009737 (Bacillus virus 1, complete genome) position: , mismatch: 8, identity: 0.733

tcaacgcctgcaatattgtaattaatcttc	CRISPR spacer
tcaacgcttgcaatattgtaaaaagattct	Protospacer
*******.*************  *. .*..

20. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP011404 (Lactobacillus salivarius str. Ren plasmid pR1, complete sequence) position: , mismatch: 8, identity: 0.733

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttaataaatgatattaaagaaggattttca	Protospacer
. *. **************** *.****.

21. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NC_010697 (Erwinia tasmaniensis Et1/99 plasmid pET49, complete sequence) position: , mismatch: 8, identity: 0.733

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ctttttaatgatattgaagaatgttttttc	Protospacer
*     *********.******* *****.

22. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP017108 (Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence) position: , mismatch: 8, identity: 0.733

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttaataaatgatattaaagaaggattttca	Protospacer
. *. **************** *.****.

23. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 8, identity: 0.733

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
aatcaaaatgatattaatgaacggtttgag	Protospacer
 *  ************* ***.*****

24. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP015177 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB267, complete sequence) position: , mismatch: 8, identity: 0.733

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
taacaaaatgatattaaagaataattaaag	Protospacer
.** ******************..**

25. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP010090 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence) position: , mismatch: 8, identity: 0.733

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
taacaaaatgatattaaagaataattaaag	Protospacer
.** ******************..**

26. spacer 1.4|24939|30|LS483446|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

tttaaagttttgcggcgatgaactgcatgt	CRISPR spacer
acgcaccctttgcggcgatgaacttcatgc	Protospacer
 .  *  .**************** ****.

27. spacer 1.5|25005|30|LS483446|CRISPRCasFinder,CRT,PILER-CR matches to KU594605 (Cyanophage S-RIM50 isolate RW_29_0704, complete genome) position: , mismatch: 9, identity: 0.7

cttgctccacccacacgttatacttgctag	CRISPR spacer
ataactccaccaacacgttatactttgagt	Protospacer
 * .******* *************   .

28. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to CP041517 (Bacillus aryabhattai strain KNU10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
gttgtctatgatattaaagaatgattttgg	Protospacer
   *   ****************.****

29. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250021 (Prevotella phage Lak-B2, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

30. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250024 (Prevotella phage Lak-B5, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

31. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250028 (Prevotella phage Lak-B9, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

32. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250023 (Prevotella phage Lak-B4, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

33. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250025 (Prevotella phage Lak-B6, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

34. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250022 (Prevotella phage Lak-B3, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

35. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250027 (Prevotella phage Lak-B8, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

36. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MK250020 (Prevotella phage Lak-B1, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaag-----aatggtttttt	CRISPR spacer
caagaaaatgataataaagaaaacaaagaa-----	Protospacer
************* *****     ** *.

37. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NC_049978 (IAS virus, complete genome) position: , mismatch: 9, identity: 0.7

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
agttaaaataatattaaagaatggtaagat	Protospacer
 .  *****.***************    *

38. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NZ_CP013122 (Fusobacterium nucleatum subsp. polymorphum strain ChDC F306 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttctaaaatgatattaaaaaatggtaaaga	Protospacer
.   **************.******

39. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NC_021277 (Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttctaaaatgatattaaaaaatggtaaaga	Protospacer
.   **************.******

40. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to KX160205 (Lactococcus phage 49801, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

41. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to KX160212 (Lactococcus phage 98101, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

42. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to MN693456 (Marine virus AFVG_25M411, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
gaagaaaaagatattaaagaataacaaaaa	Protospacer
 ******* *************...

43. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to AF323670 (Bacteriophage bIL309, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

44. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to AF323669 (Bacteriophage bIL286, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

45. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NC_002668 (Lactococcus prophage bIL309, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

46. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to KX160218 (Lactococcus phage 98204, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

47. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to NC_002667 (Lactococcus prophage bIL286, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

48. spacer 2.1|559897|30|LS483446|CRISPRCasFinder matches to KX160213 (Lactococcus phage 98102, complete genome) position: , mismatch: 10, identity: 0.667

caagaaaatgatattaaagaatggtttttt	CRISPR spacer
ttcaaaaatgatattaaaaaatggtggagg	Protospacer
.  .**************.******

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LS483446

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection