CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR027519	Thermus thermophilus isolate TTHNAR1 genome assembly, plasmid: 3	1 crisprs	NA	0	1	0	0
LR027517	Thermus thermophilus isolate TTHNAR1 genome assembly, chromosome: 1	0 crisprs	DEDDh,csa3,Cas9_archaeal	0	0	2	0
LR027520	Thermus thermophilus isolate TTHNAR1 genome assembly, plasmid: 4	5 crisprs	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,WYL,TnpB_regular.1,c2c9_V-U4,cas4,cas8b5,cas6	0	65	0	0
LR027518	Thermus thermophilus isolate TTHNAR1 genome assembly, plasmid: 2	0 crisprs	NA	0	0	0	0

1. LR027519

CRISPR-Cas detection and classification

Crispr_ID: LR027519_1

• CRISPR_ID: LR027519_1
• CRISPR_location: 37314-37444
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of LR027519_1

Consensus_repeat	Method
ACACAATGTTGTGCCTGAGCAAATGCTCGGT	CRISPRCasFinder

spacers of LR027519_1

>1.1|37345|69|LR027519|CRISPRCasFinder
AGACACAATGTTGTGCCTGAGCAAATGCTCGGTAGAAACCATGTTGCGGGTGAGCAAAATGCTCAGTAA

CRISPR arrays and Neighbor proteins around LR027519_1

CRISPR arrays

The CRISPR arrays of LR027519_1

>merge|LR027519|1|37314-37444|CRISPRCasFinder
ACACTATGTTGCGTCTGAGCATCTGCTCGGTAGACACAATGTTGTGCCTGAGCAAATGCTCGGTAGAAACCATGTTGCGGGTGAGCAAAATGCTCAGTAAACACAATGTCGTGCCTGAGCAAATGCTCGGT

>LR027519|1|1|37314-37444|CRISPRCasFinder
ACACTATGTTGCGTCTGAGCATCTGCTCGGT	AGACACAATGTTGTGCCTGAGCAAATGCTCGGTAGAAACCATGTTGCGGGTGAGCAAAATGCTCAGTAA
ACACAATGTCGTGCCTGAGCAAATGCTCGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
LR027519.1|VCU54542.1|36428_36899_-|hypothetical-protein	unknown	unknown	gnl|CDD|394873
LR027519.1|VCU54551.1|42472_42763_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54543.1|37571_38558_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54533.1|33144_33540_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54540.1|35890_36133_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54536.1|34224_34386_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54548.1|40705_41299_-|hypothetical-protein	unknown	unknown	gnl|CDD|377289
LR027519.1|VCU54544.1|38666_39419_-|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl|CDD|377379
LR027519.1|VCU54535.1|33999_34185_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54546.1|39997_40204_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54538.1|34915_35584_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54534.1|33589_33949_-|Single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|239942
LR027519.1|VCU54550.1|41800_42469_-|hypothetical-protein	unknown	unknown	gnl|CDD|225310
LR027519.1|VCU54541.1|36164_36392_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54552.1|42759_43902_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
LR027519.1|VCU54547.1|40269_40581_+|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54549.1|41295_41838_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54539.1|35585_35840_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54537.1|34529_34844_-|hypothetical-protein	unknown	unknown	unknown
LR027519.1|VCU54545.1|39599_39884_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
LR027519.1|VCU54542.1|36428_36899_-|hypothetical-protein	gnl|CDD|394873	cd02901, Macro_Poa1p-like, macrodomain, Poa1p-like family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Members of this family show similarity to the yeast protein Poa1p, reported to be a phosphatase specific for Appr-1"-p, a tRNA splicing metabolite. Poa1p may play a role in tRNA splicing regulation.	1.69943e-08
LR027519.1|VCU54534.1|33589_33949_-|Single-stranded-DNA-binding-protein	gnl|CDD|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	1.65748e-16
LR027519.1|VCU54550.1|41800_42469_-|hypothetical-protein	gnl|CDD|225310	COG2512, COG2512, Predicted membrane-associated trancriptional regulator [Transcription].	3.52251e-06
LR027519.1|VCU54544.1|38666_39419_-|RNA-polymerase-sigma-factor-RpoD	gnl|CDD|377379	pfam04539, Sigma70_r3, Sigma-70 region 3. Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.	1.72116e-10
LR027519.1|VCU54552.1|42759_43902_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	2.66603e-06
LR027519.1|VCU54548.1|40705_41299_-|hypothetical-protein	gnl|CDD|377289	pfam04298, Zn_peptidase_2, Putative neutral zinc metallopeptidase. Zinc metallopeptidase zinc binding regions have been predicted in some family members by a pattern match (Prosite:PS00142), of the characteristic HEXXH motif.	1.8669e-15

Protein sequences

>LR027519.1|VCU54542.1|36428_36899_-|hypothetical-protein
MIVKRGNFLAGLQAPGTLVAAPTNGVLTSRGLVMGAGAAKALAEAEPRLPHLFAEAVQREGILRNGVYLYGFVAVEAGGRSYGAFQTKGHFRDRADLGLVRLGASRLRRFLEARPGLEVHMAFPGIGLGGLDPREVLEALEEALAGVGNRVVLYRL
>LR027519.1|VCU54541.1|36164_36392_-|hypothetical-protein
MEVLKRFARVSGSFAVVFEEGKPVKVAGRPRPQDHAFLMELAEEVVRAFAPGKSGLVLVSPERVRVAYREKGLGA
>LR027519.1|VCU54540.1|35890_36133_-|hypothetical-protein
MVALLPNTDGVPKTRLSDRALEGLIRRHGAYVHPRLVEEGWVDLEDLEALGHVEVLEVQPLPGEKVFVPSRAGWVILEVA
>LR027519.1|VCU54539.1|35585_35840_-|hypothetical-protein
MRRTRKHLEEMAQAARALALYAEDLHAFLSEHPLEAERVAREVEEAVGVLRDLVSRLYALEARLKAPYEDNSAVALRRELFGEV
>LR027519.1|VCU54538.1|34915_35584_-|hypothetical-protein
MGHTHYWRIRTEAKEAVEKRLGAVLEDFARLLPHLPPLAGPDGTGGPVLYPPEVAFNGPAPEDYESFVFPWWEEREWSFGFCKTGFAWEDKRPYDLAVRVFLLLAKLHLGDLVQVASDAPLRDWAEAALLVESVLALPVDLYGLLEVRLLEVEDARGRRFLLERWKEDDTGLSDWLQARERMDREGLFPWPFRGPYRVLGEVHLPQEELPRRWAREGFYRRG
>LR027519.1|VCU54537.1|34529_34844_-|hypothetical-protein
MTAKEVVQRLRTEGVARVEGVVEPDPWGQEAVWFYGPDGLILQDFYEEEVAALLLEATARWADGPGAFTLDLEAGRVVVEVLEEQDYGYEVLRREEVSLEDFLE
>LR027519.1|VCU54536.1|34224_34386_-|hypothetical-protein
MKGGCWDASAFAEEAKGILEDWLRGLLTDREALEAIFQAARENNFPPESEEES
>LR027519.1|VCU54535.1|33999_34185_-|hypothetical-protein
MNELKLTPEQAVALLNLLQAEEDWEGDLPKALREVKEALKAWLKEEGLRKSPAGSYYLVRR
>LR027519.1|VCU54534.1|33589_33949_-|Single-stranded-DNA-binding-protein
MKAILKAYLARKPELVYTNQGTAIWKTSVAVRGRRKEDETVFIEVLALGGLAEALAEMDPPKGTYAHLEGRLQTETYEGKDGKKTRLTLVLDDFALLVRPKKAEEKAEGAEEAQSEEPF
>LR027519.1|VCU54533.1|33144_33540_-|hypothetical-protein
MNYSAYACALLGKKALERERVLELLEEVPDLPERAEVYLADGHLFLELAEPREEEVWALAATLEAFVLEAGPDSGGPGWAGTKEGSVELLPQNLPLLARMYEAWRRENEPVGEGDLEVFLALLREAEEEVA
>LR027519.1|VCU54543.1|37571_38558_-|hypothetical-protein
MTKVSVRSLFWASGKAASVEEALEALRRLWKEDGSVRDLMTKAAKEGYVLVDTRDVPAPFVAAVRVALARLRERLKEETPSTLLVKGTGKAKEERKPMVWESPEGVRYAVEVYDLTPREEKHWGLRDKRVEDAAKWLERFLSGVEYEEGRSPLEEALEHEDNPHFRREDLIPEDLEARLRLLGWDGSLRTLQALVDTLPAREKAFVERVRSISALVDRDKGQVVAVKSAIGWEVRQGLSREAMKAVMAVGLLQELVKEPSWKVPEARRHVEAVAEVDAHLKGLLAELEAIGTLRKAKYHLDELGRGRAIAVYRDPATGEPVYRTPVIG
>LR027519.1|VCU54544.1|38666_39419_-|RNA-polymerase-sigma-factor-RpoD
MRTDSVRLMAEGVRLLTREQVMRAFIAEDYEALGRHYYALALKEGFSRFHLLGDEALDLAQEVALKVHSSLKAWRTGERKLPSPSKNLTFWVMVEADRAVREWFYRNRGVGYTNSRLVAKVKRATEGLQAELGREPTPEEVAERLGIPLEVVEEALAVAEAEAILSLDDTTEEGTRLEEFVGHDPWEREEERDFAFKALEEAIERYGLRRKLGEKEAELLERFLEGGLEEEELEELEAALKEAMTRTQAV
>LR027519.1|VCU54545.1|39599_39884_-|hypothetical-protein
MLREQNKRLAKQAVREVFRSRLFWLMVAGGVVLDLAREGTWLLYLAAGVFLFLMVLGFLFSRPSLFSNPFDPFWSLEEEARGLRREVRRLRRGR
>LR027519.1|VCU54546.1|39997_40204_-|hypothetical-protein
MEEKVLIFKDTRHQEAFRKALERASLGRAVIRPDHGWPKPALRVRGVNLSHVLAAAIWAGFEPEVVLE
>LR027519.1|VCU54547.1|40269_40581_+|hypothetical-protein
MLAEAFREYARPKGQGRAYLENLAGFFLAVARDQGEEEQVRMVIGEDPVLGPYLDVDLREAPRTHAWLSAFREAAKEGAALALQENEDGTVDATVLPPRKAEA
>LR027519.1|VCU54548.1|40705_41299_-|hypothetical-protein
MNGVLLALTGLALVAGYAVYLAFTVLRYRGVPVPLEAGPFAEEALRKGLTGFRVRVGRRNGVRYPERSVYLTRAVYEGKSLYHLAVAVHEVGHALQWRERPEMVRAAQGALTLALGLLVLGFLVGPSPLGAAFLTGGYGLFLASLPLEVDANRRGLEVLPPEWREEARRVMAALTGSYVAVPLGGLLVAVGFLVGWS
>LR027519.1|VCU54549.1|41295_41838_-|hypothetical-protein
MASTAGRRGLRPELLGALAGLLDGPWGAPFTGALFARRVGWREAFFSGLGWLTAGMKGASPLLALWVGQGVLALWRRGGWWRLGAGLAFLLGGLLFRGLWLAPLGVVLAGVLPGGWRYAALALAGVGVYGWTGLLLSLGAWAAETVGLERGERFRGMDVPALVYGGVLLLRNMLLEVVNG
>LR027519.1|VCU54550.1|41800_42469_-|hypothetical-protein
MLRVYAQAAIAAAAMPVVGFITGKVVGEAASKAPLLAGVGVVVYAVALAASYAHLRHYYARFDGEGVRASPFIAFAVEVATFYLSFASVVLESRWALWGSLIGAGVVFWGNLTSMSLGLAERKRGVDTRAPAAFPVEPQEVNGAVNAVEPRREEREEALPVPLEKEELSLLGALEVPKGPSALARELGWPKSTVAKRLQRLVSRGLVEARDGVYRRTERASA
>LR027519.1|VCU54551.1|42472_42763_-|hypothetical-protein
MNGEDVAFKAGDVVFTVPRSMFRADVNGVVQVGEHQVPAKVIYAAWAVGVDEGVKAGVVLGAGLSLVLVLGVLFLLRAVNAWRERRRWTPLDRVLR
>LR027519.1|VCU54552.1|42759_43902_-|hypothetical-protein
MEALWKEIADKLSSFEEEVAKEVLEKAKGVFPTRRAKEAFRALAGRSATPLEEPLLRVATALVEEGLAGSYEEAFGVLGVEAEPTQKDPAPSQAPPPAEAAQAPSPVEASPPVEASPPAPSPPVEAPSPRQASPQGVPLTGKQPAGAPPPPSRAEKTSRSQDQNEAARDSRWRRAYQEVFGQDPSEDPLLYRERLAHALLFYRPEQGRRRAFEEVREVERRLQESRSRTRELLGSEPQVDVGAAYIQLGKLSAQLEDLARRVERLEEAVQKEASRFGGVNAALRLHHQEIRALKALVEGLRTGDGVDWKRLEAAVRAAKAEAIQEAEERIQGATALWRGEVEPRLKALEEWAKRITEAFRRTLEARERRKGLFGLFGGER

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR027519_1	1.1|37345|69|LR027519|CRISPRCasFinder	37345-37413	69	NZ_LR027519	Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence	37345-37413	9	0.87

1. spacer 1.1|37345|69|LR027519|CRISPRCasFinder matches to NZ_LR027519 (Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence) position: , mismatch: 9, identity: 0.87

agacacaatgttgtgcctgagcaaatgctcggtagaaaccatgttgcgggtgagcaaaat	CRISPR spacer
agacacaatgttgtgcctgagcaaatgctcggtagaaaccatgttgcgggtgagcaaaat	Protospacer
************************************************************

2. LR027517

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	554045 : 558815	8	Faecalibacterium_phage(33.33%)	NA	NA
DBSCAN-SWA_2	1406302 : 1429904	41	Thermus_virus(97.22%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>LR027517|554045:558815|DBSCAN-SWA
CCTAGCCGTGCTGGATCTCCCCGAGCACCACGAACTCCAGCTCCACGGTGATCCGCTCCGTGTCCTGCTCCACCCCGCCGAAGGAGCGCTTGGTGAAGAGGCAGTCCTTCAGGGTGTCGGTGACGGCGGTGCCGTTGCCCTTGTCGTAGGAGATGACGATGTCAAAGGGGTCAAGCTTGTAGACGTTTCCCTCGGGGGCGGCGGCGCGGAGGCGATCGTACTCCTCCCGCAGGAGGGTGAGCTTCCCCGAGGCCTCCCAGTTGCCCTTGGTGTAGCCCCTGGGGGTGCGGCCCTTGCCGTAGATGGCGTTGACCTTTTCGGAGTCCTCGTAGTCAATGGAGAGGACGTCCGCCAGGGGCACGCCCTTCACTTGGATGCTGATGTGCTCCCAGTCGTAGTAGCGGCCGTTAATGGGCATGCTCACCTCCTCACCCCACCAGGAAGGGGTTTTCAAAGCCGATGTCCATGACGATCTCCCGCAGGTAGCCCAGAGGGACGATGCGGATCTGGAGGCGAAGGGTCTGGGAGGCCAGGATGTCCTGGCCGGGAGGGGCCACCACGCGGCCCCGGGCGATCTCCCCGGCGGCCTGCATGAGGCGGAGGGGGGTGTTGGCCCGGGCCAGGAGGCTCGCCAGGCTGGCCTTGAGGTCGGTCGGGTCCACGTGCCACTGCACGAAGTCCAGGAGGGCCTGGCGCACCTGGTAGGTGGCCTTGTCCATGACCCGGCGGTTCTGAATCACCTTGTAATCGCTGGTGGGGGCGGCGGCGGTGCGGCCCTCCACGAGGAACCACCCGTCCCGGCCGATGAGGCGGTAGACGGTGGTGAAGCCCGCCTGGTCTAGGGCCAGGGCGTGGGCGTTGTTGAAGAGGGACTGCTTGCCGAAGGGGGTGTCCACGAAGGGGGCCACCTGCACCACCCCGCTCAGGGGCCCGAGCTGGACCCAGGCGGGGGAGACGTGGACCCGCTGGCTGGAGATGCGGGCCCCCACGCGGGAGGCGAGGCTCTGCACTTCCAGCCTGCCCGTGAGGGTGTCCACCACCTCCCCCCAGGCGGCCACGATCATCACCCGTTTGTGGCTGAAGCTCGCCTTCTCGCTCAAGCGGGCGTTGACCCAGGCGTCGGGGTCGTTCCCCGGGGGCAGGGTCTCGGTGAGGAAGAAGATGTAGCGGAAGTTCGCCTCGGCCTCGTCGGCCAGGGCGCCCAGGGCGGCCCACATGGCGGGGCCGGTGGGCTGGGCCACCTGGATGTACTCGTACTGCAGGTTGGTGTTGAGGGCGGCGCGGACGGCGGCCTGGACGCTAGAGACGCTGGCCTGGGGGGCGGTGGCCTGGAAGCGGTAAGTGGCCCCCGCGGCGTAGGTGCCGGTGGCGAAGTTCAGGGTGAGCCCCGTCCCCGGCAGGGTGTAGGTGGCGGCGGTGGCGATCTCCTGGCTGGTGGTGTCCCCGCCGTCCAGGCTGTAGGTGAAGGTGGCCGTGTTCAGAGCTCCCCCCCTGACGATGCGCACCACGATCTCGTAGGCGTCCAGGGGGCTTCCCGTGATGGTGACGGCGGGGGAAGAGGGGTTGCCGCTGTCCGCGGCCACGCTCCCCGCGATGTCGGCTTGCGCCCGCACCGCGTAGACCTGGCCGCCCCCGTAGGCCAGCTGGTCGGCCACAGCCCGGGCCAGGGGCCCGGTGCCCAGGACGCCGGGGACGGCGGCGAGGTCGCTGAAGGCCAGGACCTGGTTCACGGGCCCCTGGCTGGAGACGCCCACCACCACCCGCTGGCCCTCGCCGCTCGGGGCCACGATGCCCAGGCCCCCGTCTTGGATCTCTGGGTAGACGCCGGGTAGCCTTGCCATCCTCTATCTACCTCCTACCTGTGGGTGGGCCCCTGGAGGAACTCCTTCAGGGCCTTCTCAAACTGGGCGCGGGAGACCCGGGTCCCCTCGGCCCAGCCCGCGTAGACCTTGAGCCCCGCGAAGGCCCACGGGGGCACCCCCAGGGCCTGGGCGTGCTCCTCAATGGTGGGGAGCTCCTCTTGCGCTTCCTTCACCTCTTCTTTGGTTTCCTTGGGCATGCTATACCTCCTCTTCCAAGACGGCCTCTTCCACCTCCACCCGGACGGGCACCCAGGCGGTGTCCTCGTAGAGGGCGATCTCCACGGGGACTTCCAGGGCCAGGGCGTTTTCCCCCACCAGGAGGCCTTCCTCGTCCAGATAGGAGAGGGCGATATCGTTCAGCTTGGCGTGATAGTCCTCCCCCACGTGCAGGGGGGTGTCCCACATATAGAGGAGAACCCCGGCGAGGAGCCGGTCCAGCTCCTCGCTGGAGCGGGCATAAAGCTCCAGGCGGATACGTAAGGTGCCTCCATAGAGCCTGCGCCGGGTCTTGACGGGCCCGGCCACTACCCGGCTCCCGTCCCGCTTGAGGGCGCCGGTGAGGGGCTGGATCAGGGCGGCGGGGGCCACCCGGTAGGCCTCCTCTCGGGCCTTGCCCACCAGGACCCGGGCGGGGGGCAGGCCCGCGTGGGCGCAGGCCGCCTTGAGGTACTCCAGCACCGGGGCGATCACCGCGTCGCCTCCTTCATCCACTCCAGGAGGAGGGCCTTGGCCTCCTCGCGGTCTTCCTCGGTGAGGCCCAGGAAGGGGCGGGCGGGGATGTAGACCTTCCGCCCCCTCCCGGCGTAGCCCCCGAACTGGTGGATGCGGGCGTACTCCAGGTTAGTGCCCACGTAGATGCGGCTTCCCGCCACCTTCCAGGAGATGGAGTTCTTCAGGCGGGCCGTGACGACCAGGGGCTTGCGCAGGGCCAAGCGCCTCTGGGCGGCGGCGGAGATCCCGCCCCGCTTGAGCCGGTCCCTGGGCCGCACCTCCTTCGCCAGGGTGGCGGGGGAGAGGGGCGGCCAGGGGGAGCCGTCCGGGGCCCGGCTCTCCTCAAAGCGGCGGTGGGTGCGGGCGAGGATCCCCTCGGCGATGGCCTCCTTGACCTTCTGGGGGACGCCCCGCCCGAGCTTTCTCAGGGCCTCGTTTAGCTCCCGCCAGTCCCCTTTGAGGCGCACGCCCATCAGAAGTCCTCCAGGCTCTCCCGGGAGAAGACCCGCTTCCCCCGGACGGCGGCCCCGCCCTTGGGCCTCGCGGGCTCCCCCGTGGGGGGGAGGGGCAGGGAGGCCTTGCCCACGGCCACGTCCCGAAGGAAGGCCACGGCGTCCCGGTATCGGGTGAGGGCGGCCTCGTCGGCGGTGCCGGGCCGGATGCCCCGGCGGAGCATGAGGCGGTAGACGGCGATGTCCACCGCCTTGGCCTTCAGCACCTCGGGGAGGGAGAGGAGGGGGAGGGCGTAGCGCTGGGCGAGGTAGCTTTCCACCTCGGCCCAGGCCTCCCTCAGGGCGGCTTCGGCCCGGGCCTGGCCCTCGGGCGTGAGGACCCCCGCCCCCTCCTCGTCCACCAGGTAGAGGAGGACGTCTAGGGGGAGGGCTTGGCGGAGGTCCTCGAGGGTGATCATGCGCCGGTGCCGGTGCCGGTGGAGCCGTAGGCCAGCTGCCAGAAGAGGTAGCCCGCCGCTTTACGCTCGTAGACCCCGTAGATGAAGACGTTGCGCTTGAAGACCTCGTCGGAGGTCTCGGGGTCGTCCTTCGCCACCCACTCGGGGCGGCTCCGCCGCTGGAGGACGAAGGGGCGGATGGCCTGGCTCCCGTCCACCAGGAACCAGTAGGTCTCGTACTCCTCCACCAGCCAGGGGCTGACCAGGATCTCGGCCTTCCCGTAGTCGGGGTTGGCCCCGCCCGAGGGTAGGGTAGGCACCCCCACGATCTCGTAGGCGGTGCTCTCCAGCCCGGGGCCCACCACCAGGTAGATGGGCTTTTGCAGGAAGAAGCCCAGGGGGTAGCCTCGGGCGTCGGTGAGCTGCCTCATCTGGCTCAGGGCCTGACGGAAGGCCTCCCGGGTCAGGGGAGCATTGCTCGCGTTCTGGAAGGTCCGCTTCCCCACCGTGTGGGAGCCGAAGAAGGGGCGGCCGTCGTAGCCCTTCTGCTGGAACCCTTTGCGCAGGAGGTCGGCGATGAGGAGGTCGTCGTGCTCGGCCCACCTCCGGGCGTACTGGAGGGCGGTGATGCGGATGAGGTCCATCTGGTCGTCCTCCACGTCCGTGCGGGACACGGCGAAGGTGGCCTCCCAGTCCGCGTTGACGATGGAGAAGGTCTCGGCGGTGAGGTTCTGAACCTGCCGCTCCCCCTCCCAGAGGCGCATGGTGGGCATGTTCTCCATCCAGGCGTAGTAGTTGGCCCGGCCGTTGGACTGGACCTCCAGGGCCAGCTTCGGCCAGAGGGGGGTGTACCCCTCCTTGGCCTCAAAGACCAGGGCCCTGAGGGTTCGGCTTAGGGCGCTCAGGTTCTCGCGGTTCAGGATCATTACCACACCTCCACCCAGACGTAGTCCGGTTCCACCTTCAGGGCCCGGCCCGCCTTGGAGCGGCCCGTGCCCGTTTTGCCCACGGTGTTGGGCCCGGTGGCGTACACGTCCCGCCCGAGCTCCGTGGGCCCCACGGGGTCGGCGGGGTCGTTCTCAAAGCGGAACACTCCCCGGCGCACCAGGACCTTCTTCGCGCCGTCCGTCCCCCCGGTGTTGTCCACCGTCTCCTGGGCCACCCCCAGGGCGATCTTCCCGGTGCCGGGGGCCGCCTCCTCGGCGTAGCCCCCGCTCACCATCACCAGGGCTCCCTGCCGGATGACGGCGTTCGCCTTCACCGGAAGGGGGATGAGGTACTCGTCCGCCCAGCGCTCGGTGTCAAACAT

Protein sequences of DBSCAN-SWA_1

>LR027517|554045:558815|557523_558432_-|VCU52874.1|DBSCAN-SWA
MILNRENLSALSRTLRALVFEAKEGYTPLWPKLALEVQSNGRANYYAWMENMPTMRLWEGERQVQNLTAETFSIVNADWEATFAVSRTDVEDDQMDLIRITALQYARRWAEHDDLLIADLLRKGFQQKGYDGRPFFGSHTVGKRTFQNASNAPLTREAFRQALSQMRQLTDARGYPLGFFLQKPIYLVVGPGLESTAYEIVGVPTLPSGGANPDYGKAEILVSPWLVEEYETYWFLVDGSQAIRPFVLQRRSRPEWVAKDDPETSDEVFKRNVFIYGVYERKAAGYLFWQLAYGSTGTGTGA
>LR027517|554045:558815|557089_557527_-|VCU52873.1|DBSCAN-SWA
MITLEDLRQALPLDVLLYLVDEEGAGVLTPEGQARAEAALREAWAEVESYLAQRYALPLLSLPEVLKAKAVDIAVYRLMLRRGIRPGTADEAALTRYRDAVAFLRDVAVGKASLPLPPTGEPARPKGGAAVRGKRVFSRESLEDF
>LR027517|554045:558815|554472_555885_-|VCU52869.1|DBSCAN-SWA
MARLPGVYPEIQDGGLGIVAPSGEGQRVVVGVSSQGPVNQVLAFSDLAAVPGVLGTGPLARAVADQLAYGGGQVYAVRAQADIAGSVAADSGNPSSPAVTITGSPLDAYEIVVRIVRGGALNTATFTYSLDGGDTTSQEIATAATYTLPGTGLTLNFATGTYAAGATYRFQATAPQASVSSVQAAVRAALNTNLQYEYIQVAQPTGPAMWAALGALADEAEANFRYIFFLTETLPPGNDPDAWVNARLSEKASFSHKRVMIVAAWGEVVDTLTGRLEVQSLASRVGARISSQRVHVSPAWVQLGPLSGVVQVAPFVDTPFGKQSLFNNAHALALDQAGFTTVYRLIGRDGWFLVEGRTAAAPTSDYKVIQNRRVMDKATYQVRQALLDFVQWHVDPTDLKASLASLLARANTPLRLMQAAGEIARGRVVAPPGQDILASQTLRLQIRIVPLGYLREIVMDIGFENPFLVG
>LR027517|554045:558815|554045_554462_-|VCU52868.1|DBSCAN-SWA
MPINGRYYDWEHISIQVKGVPLADVLSIDYEDSEKVNAIYGKGRTPRGYTKGNWEASGKLTLLREEYDRLRAAAPEGNVYKLDPFDIVISYDKGNGTAVTDTLKDCLFTKRSFGGVEQDTERITVELEFVVLGEIQHG
>LR027517|554045:558815|558431_558815_-|VCU52875.1|DBSCAN-SWA
MFDTERWADEYLIPLPVKANAVIRQGALVMVSGGYAEEAAPGTGKIALGVAQETVDNTGGTDGAKKVLVRRGVFRFENDPADPVGPTELGRDVYATGPNTVGKTGTGRSKAGRALKVEPDYVWVEVW
>LR027517|554045:558815|556104_556596_-|VCU52871.1|DBSCAN-SWA
MIAPVLEYLKAACAHAGLPPARVLVGKAREEAYRVAPAALIQPLTGALKRDGSRVVAGPVKTRRRLYGGTLRIRLELYARSSEELDRLLAGVLLYMWDTPLHVGEDYHAKLNDIALSYLDEEGLLVGENALALEVPVEIALYEDTAWVPVRVEVEEAVLEEEV
>LR027517|554045:558815|555899_556103_-|VCU52870.1|DBSCAN-SWA
MPKETKEEVKEAQEELPTIEEHAQALGVPPWAFAGLKVYAGWAEGTRVSRAQFEKALKEFLQGPTHR
>LR027517|554045:558815|556592_557090_-|VCU52872.1|DBSCAN-SWA
MGVRLKGDWRELNEALRKLGRGVPQKVKEAIAEGILARTHRRFEESRAPDGSPWPPLSPATLAKEVRPRDRLKRGGISAAAQRRLALRKPLVVTARLKNSISWKVAGSRIYVGTNLEYARIHQFGGYAGRGRKVYIPARPFLGLTEEDREEAKALLLEWMKEATR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VCU52868.1|554045_554462_-	hypothetical protein	A0A2K9VGX6	Faecalibacterium_phage	9.4e-19	34.3
VCU52869.1|554472_555885_-	hypothetical protein	H7BVM2	unidentified_phage	3.0e-24	26.5
VCU52870.1|555899_556103_-	hypothetical protein	NA	NA	NA	NA
VCU52871.1|556104_556596_-	hypothetical protein	NA	NA	NA	NA
VCU52872.1|556592_557090_-	hypothetical protein	Q6QIB8	Burkholderia_phage	1.5e-10	40.4
VCU52873.1|557089_557527_-	hypothetical protein	A0A2K9VH41	Faecalibacterium_phage	1.3e-10	40.2
VCU52874.1|557523_558432_-	hypothetical protein	H7BVL8	unidentified_phage	1.4e-46	37.5
VCU52875.1|558431_558815_-	hypothetical protein	A0A0M4TU84	Ralstonia_phage	8.1e-17	43.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>LR027517|1406302:1429904|DBSCAN-SWA
CTCAGTACGCCTTGGCGAAGACCACCCGCTTGCCGTAGGCGGAAGGCTTCCCGCAGCGGACGCAAAGACCCTCCTCCGCCTCGGCCTCAAAGGGCACGCAGCGGGTGGTGGCGGTGGTCTCCTCTTGGATGAGCCGCTCGCAGGCCTTGTCCCCGCAGTGGAAGGCCAGGGCGAAGCCTTCCTGCACCGCCTCCTTGAAGGCCTCGTAGGTGTCCACCTTGTGGGTGTGGGCCCTCTGGAAGTCCAGGGCCCTTTGGTAGAGCTCCTCGTGGAAGGCGTCAAGCTTCCCGGGCAGAACCTCGGGGAGGGCGGCGAGGGGCAGGGTCTCCTTGCCCCCAAGGCGGCTCGCCAAGACCGCCTGGCCCCCTTCCAGGTCCTTGGGCCCGAGCTCCACGCGGAAGGGCACCCCCTTGAGCTCCCACTCGTGGAACTTGTACCCCGGGGTGTGCTGGTCCCGGTCGTCCAGGTGGACCCGAAGGCCCTTGGCCTGAAGGGCCTGGCGGAGGCCTTGGGCGGCCTCGAGGACCCGCTCGCGGCTTTCGTCCTTGTAGATGGGGACGATGACCACCTGGATGGGGGCGAGGCGAGGCGGGAGGACGAGGCCCTTATCGTCCCCGTGGGTCATGACGATGGCCCCGATGAAGCGCCAGGAGAGGCCCCAGCTCGTGGTGTGGACGTACTTCACCTGGAGGTCCCTGTCCTGGAACTTGATGTCAAAGGCGCGGGCGAAGTTCTCCCCCAGGTAGTGGCTGGTGCCCGCCTGGAGGGCCTTGCCGTCCTTCATCATGGCTTCAATGGTGGTGGTGTAGACGGCCCCGGCGAACTTCTCCTTCTCAGTCTTCAGGCCCTCAATCACGGGGATGGCGGCGTACTCCCGGGCGAGGCGGGCGTAGATGGAGAGCATCCTCCGCACCTCCTCCTCCGCCTCCTCCCGGGTGGCGTGGGCGGTGTGCCCCTCCTGCCACAGAAACTCGCTCGTGCGAAGGAAAGGCCGCGTGCGCATCTCCCAGCGCACCACGTTGCCCCACTGGTTCAAGAGCTGGGGCAGGTCGCGCCAGCTCCTGATCCACTTGGACCACATGTAGCCGATGACCGTCTCCGAGGTGGGGCGGACCGCCAGGGGCTCCTCCAGCTCCTCGCCCCCCGCGTGGGTGACCACGGCGAGCTCGGGAGAGAACCCCTCCACGTGCTCGGCCTCCTTCTTGAGAAAGCTCATGGGGATGAAGAGGGGGAAGTAGGCGTTCTGGTGGCCGGTCTCCTTGAACATGCGGTCCAGAACCTGCTGGATGTTCTCCCAAATGGCGTACCCGTAGGGGCGGACCACGATGGTGCCCCGCACGGGCCCGTAGTCGGCGAGCTCGGCCCTTTGGATGACCTCGAGGTACCACTCGCTGAAGTCCTGGCTCTGGGGGGTTAGGCCCTTCTCCTTCGCCATACCCGCCCATCTTACCCCAGTAAAATGGCCCCATGGACCTCTTCCCCGTTCTCAAGGAACTCGCCCAGAAGACCCCGAGCAAGATCCTCCTCATCGTCTTGGACGGCGTGGGGGGGCTTCCCTTGGAGCCGGGGGGCCCCACGGAGCTCGAGGCCGCCAAGACGCCCAACCTAGACCGCCTGGCGGAGGAAAGCGCCCTGGGCCTCCTCACCCCCGTCTACCCCGGCCTCGCCCCGGGCTCCGGCCCAGGCCACCTCGCCCTTTTCGGCTACGACCCCTTCCGCTACGTGGTGGGCCGGGGGGCTTTGAGCGCCTTGGGCCTCGGGGCCGACTTCCGGGAGGGGGACGTGGCCCTAAGGGGGAACTTCGCCACCTTAGACCCTGAGGGCAAGGTGGTGGACCGCAGGGCGGGAAGGCCCCCCACGGAGGAGAACCAGAGGGTCATCGCCAAACTCAAGGAGGCCATCCCCCGCATAGAGGACGTGGAGGTCCACTTCTACACGGAAAGCGAGCACCGCTTCCTGGTGATCCTCCGGGGAGAAGGGCTGGAGGACAAGGTGACGGACACCGACCCCCAGAAGACGGGCCTGCCCCCCCTAAAGGCCAAGGCCCTGGACGAGGCCTCGGAGAAGACGGCCAGGATCGTCAACCTGCTCTCGGAGAGGATCCGGGAGGTCCTCAAGGACGAGCCCCGCATGAACGGGGCCCTCTTCCGGGGGGCCTCCAAGAAGCCAAGCTTCCCCCGGATGCAGGAGGTCTACAAGCTTACCCCCGCCGCCATCGCCAGCTACCCCATGTACAAGGGCCTCGCCAGCCTGGTGGGCATGGAGGTCCTTCCCGTGGAGGGGGAGGGGGACGCCCTGGAGGGGAAGCTCAAGGCCCTAAAGGAGAACTGGGGGCGGTACGACTTCTTCTACTTCCACGTGAAGAAGACGGACGCCATGGGGGAGGACGGGAATTTCCGCGGAAAGGTGGAGAAGGTGGAGCTCTTTGACGCCCTCCTCCCCGAGATCCTGGCCCTAGGCCCGGACGTCCTCGCCATCACGGGAGACCACTCCACCCCCGCCCTCCTCAAGGCCCACTCCTGGCACCCCGTCCCCCTCCTCCTGAAGGCCCCCTACCTGCGGGCGGACGAGGCGAGGCGCTTCACGGAGAGGGAGGCCCAAAGGGGAAGCCTCGGCCACCTCCGGGGGGTGGAGCTCATGCCCCTCCTCCTCGCCCACGCGGGGAAGCTCTTGAAGTACGGGGCCTAAAATGGGGAGATGATCCGCCACCGCCTGAGCCTCGAGGAGTTCCAGGCCCTCCTGGAGAAGGCCCCAGAGGGGCTTCGCCTGGAGCTCTTGGACGGCGAGGTCTACGAGATGGCCCCCATCGGCAGCGGACACGCCAGCCTGGTGACCTACCTGACCAAGCAGCTGGAAAGGCTTTACGGGGACCGGGCCCTGGTCTACGTGCAAAACCCCCTTCGTCTTTCCCCCCACTCCCTGCCCCAACCGGACCTCGCCCTGCTCCGGCCGCGGGAGGATTTTTACCGGGAAAGGCTCCCCGAAGCCGGGGACACCCTCTTGGTGGTGGAGGTCAGCTTCTCCACCCGGGAAATGGACCTTAAGAAGCTCGCCCTCTACGCCCAAGGAGGCGTCCCCGAGGTGTGGCTCGTGGAGGAAGGGGGAAGCCTGGAGGTGTACCGGGAGCCCCGGGGCAACCGTTACCGCCACCGCCTCCTTGTGGAGCCCGGGGAGGAGGTGGCCCCCCTCCTCCTCTCCCATCCCCCTCTCCTCTGGGACCCCCCTAGAGGTACCCCGCCCGCGTGAGCTCCTCCTTTACGGCCTCGAGGACCCTCTCGTAGGCCTGGTCCAGGTCCAGGCCCTTCAGGGTGGCCCCGGCGGCGGGGACATGCCCGCCGCCCCCGAGCTTCAGGGCGATGTTCTGGGCCGAGACCCCGCCCCGGGAGCGGATGGAAACCTTCACCCCCTCCTCCCGCTTGCGCAGGAAGACCGAGACCACGCTCCCCTCCACGTAGCGGATGAGGCCCACGAAGTCGTCGGAGTCCTCCTCGGCCCCCGCGTCCTCGGGCAGGTGGGCGGTAACGAGAAGCCCGCCAAAGTGAAAGGCCACCGTGGAAAGAACCTTCCCCATGAGGCGGAAGTAGGAGGGGGGGCGGAACTGGAGGCGGTCGGTGAGCTCGGCGAGCTTCACCCCGTAGCCCAAAAGCTCCGCCGCCACCCGAAGCACCTCGGGAGTGGTGTTGGCGAAGCGGAAGTTGCCCGTGTCCGTGAGGATGCCCGTGAGGACGGGGGTGGCGATCTCCGCCGTCCACTCCACGCCCAAGAGGTCAATGAGGTCCTTCACCATCTGGGCCGTGGCCGCCTTGGAGGGGTCCACCACGTGGAGGTGGCCGAAGCGGGGGTTGGTGCCGTGGTGGTCTATGTTGATGACGAAGCCCTCCACGGGGACCCCCACGACCCTCGAGGGCTCGGCGCTGTCCAGGGCCACCAGGGTGGCCCCGGGAGGAAGCTTCTCCACGGGGTCGGAGTACTCCTCCTCCTTGGGGAGGAAGCGGAGGAACCTCGGCGGATCGGCGACCCAGTAGGCCTCCTTGCCCAGGGCCTTGAGGGCCCGGTAAAGCCCCAGGGAACTTCCGATGGCGTCCCCGTCCGGGTCCACGTGGGTGGCGATGTAGATGGGGCCCTCCACCGCCTTGAGGACCTCCGCCACGAGCCGCATCTTCTCCCAGTACCTGGGTTCGGGCGCGTTGCCGTCCATGCCGCTAAAAGGCTAGCACAAGCCGGCCCCCCGGACCCGGGATACAAAGACTTTCCCCCCTCGCGGGAGGGGGGTCCTTGGTGGGCGATGGTGGACTTGAACCACCGACCTCACGCTTATCAGCACTAAAAGGTCGAGAGGCAAACTAAAGCAAGCGTGGCCGATTTCCCTTACTGGAGGGCCTTTTTTCGCCCAGCTTTGGAGGCGGATCGATCCCGTTTGTTGCGGTTCTGAAGGTGTAGCAAGGTGTCAAGGGGAAGGGCCGCTTCTTTGAGGTCTTCGTTCATAAGCTGCTGGTAGACCTGGAGGGTGAGCTTCACGTCTTTATGCCGCAGGCGGGCAGCCACCACCTTCGGCGGGAGGCCCGCCCGGAGGGCGAGGGAGGTGTAGGTGTGCCGGAGGCCGTGGGGGGTGATGCGGGAGACCCCGGCCTTTTCCTGCAGGGCGTAGAAGGCCCGCTTGAAGTTGTTGTATTCCAGGGGTGTTCCCTTGGAGCTGGGGAACATGAGCCCGTGGTCCTGCCAGTCTGGGGTGGAAGCCTTCTCCTCCTCCAGGCGCTCCCGCCACCAGGCGAGGAGGGCTTGGGTGTCCGGGTCCAGGTAGATGGGGGCCACGCTTCCCGGCGTCTTGGCCGGGCCCAGGGTGCCGTCCCGGCGCAGGGTGTGCCGGACGTGGAGCACGTCCCCCTCCCAGTCCTCCCACCGGAGGGCCAGGGCCTCCCCTATCCGCAGGCCGGTGGCCAGCATGAGGGCAAAGAGGGGGAAAAGGCGGTGCTCCTTGGAGGCCTCCAGGAAGCGGGTCACTTCCTCGGGGGTCCAGGCCCGGGCGGGGCGCACAGGCCCCCCCTCGGGAGGATCCACCGCATCCATGGGATTGCTGGGGATGAGGTCGGCCCGCACCGCGTCCCGAAGGGCAGCCCGGAGGAACTGGTAGATGTGGCGGCGGTGGGAGGGGGACAGATAGGCCAGGCCCTGGAAGAGGGCGCGAAGCTGCAAGGCAGTAAGGCGGGAGATGGGGGTGTGCAAGACGGGGTCCAAGTGGCCCAGATAAACCCGGTAGTTGCGCACCGTGGTGGGCCGGAGGGCCTTGCGGGTGGTGCGCTCCTCAATCCAGTGAAGAAGCCAGTCCCCCAACTTCAGCCTGCCCGCGTCCGGGATGGTGCCCGTCCAGGCTTGGGGCAAAAGGCGGGCCAGCTTTTCCGCTACCTCCTGGCGGGTGCGGCCATAGACCCACTTCTTGACCTGACGTCCATCCGGGCGGCGGCCCAGGGTGACGAAGCCCGCCCAGCGCCCGTCCTTGCGGCGGAAGATGGAGCCTTCTCCCCTGCCTCGTTTACGCTTCATAGGCGGCTTTTGCTCAAAAACCTCTGTCAGTTCCAATCAGAAAGCCAGACCTTCAGCCGGCCATCCGCATCTGGCTTGATGAGGTAGTAAGTGCTGAAGGCTTTGTTGAGCACTTCCTTGGGGGGCCTGTCTTGGCAAACCAGGGTTTGCTGCCACTTCTTGCTGACGTAGACTTCGGCCATGTCGAGCAGGGCTTCTACGGCGGTGATCCGCATGGGTTCAAGCTCTTCGGTCCGAAGCACGCACCCCCGGCTCTGGCGTTCCCGGATGAAGGGGAGAACCTTCCGTTCCAGGAAGTCTGCGAAGGCCCACTCGTAGAGGGGGGCCCAGTCGTTGGTGCTCAAGGCGTAGCGATAGGCTGAGTCGTAGCCCCTCACCACGGCCTCGGGTGAGGAGACCGGGCGTTTGGCCTTTTGGGGCGAAGACCCCTGCGTCAAAAGGAAGAGGAAACCGAGGACTATCAGGATGGCGATGCCCACGTAAAGTGTTTCCTTCCGGGTTTGGGCAAGCCAGTTTTTGAAGTGGATTGCGAGGCCATCCCAAAATCCCGGAGACTTTGGCGCTTCCCAAAGACCGAGCTTGCGCATGGCGGCCTCGGAGGAAGCCGCCTGGTATAGAAGCCTCAACTCCTCGGGTCCCCAGGTCAGCACCCCTAGGGCTTCGGCGTTTTCCAGCGCCGGCTTGGTGAACCCCGAGGGGCAGATGAGGATGCCCTTGTGGGTCCTGTGGAGGTCTTTGGCCGCATGGGTCAGCCTCACCAGGTTGGCATCTGCGGGCGTGGAAAGGTTTTTGCACTGGATGAGGTAGCGCTTGCCCTGGGGGCTTATGGCTTCCACGTCAAGGCCGTTGTCCGGGGCGTTGGTCTGGCTTGGGCGGGAGGCCTTCCACCCGGGCAGGCGGGCGAAGAGGGCCTGGACCACCACCTCAAGAAGCTCCCCCCTATCCGCCTGGACCAAATAGGCCGGGTCCTCAAGCAGTTTTAGCAGCGGATCGGGCCTCATTTGACTTCGTGGGAAAGACCCCCCTATGAGCCAAGATTCAGTCAAGGTGCCTATTGTTTCTGGGCGTTCCATTCAAGGTAAACGCTCACCATGTTCTGGTTGGAAGGGCACTGGCTCGTGAGGGGGCTGATGGTTTTGCCGATGAAGTAAGTGCCTTGTATCCGACCTTCAAAAGCGATTGAAATGACGGAGTTTCCAGACTGGGAGCTAAATACCATGTTGCCGTTTATGGTGCCGTCCTGTCTTATTTGCGCGGTCACGTCTCCGTAAGCGGCGGGTTGCCCGGGGGTATAAGCTCGGACGGTGCCCGACACATTTGAGCCGCTTTGGTTGAGGGAGAATCTTAACTCCCCTGTGTTTATCGGGTCTTCAGGGCAATCTGCTTTGTTGAGGGGGCGAGTTTTAGCCGTGAGGTCAAGCCACGTGCCGGTGGCGTTTATGGGCGGGTTGGAGCTGCATGCCGCCAGTACCAGGCCGAAGACCACTAAACCCCACCGTATTCCTGATGGTTTCATATCACTTCACCTCCCGGATGCTGATCTTCCGGTAGACCTCCCCAATCACGCGCACTTCCTCGGGTTCCAAAAGCGGGCCTTTCGGGTTGTCCGAAATCAAAATCCAGCGGTTGCCAAGCTTGCGGGCCCGTTTGATGGTGATGCCGTCCCCGATGATCTCCACAGCGTAGACCCGGCCTTCCCGAAGCTCCTTGAGGTTCTGGTCCACCAGGACAAGGTCTCCGTCCCGGAGACCGTCTTCCTCCCCGGTGTCCATGGAGTCCCCTTCCACCTGGATGAGCACGGAGCCCGGGCGTACCAGGGGGCGGGGGACGGGCATGCTCCCGGACTCGGGCCAAGGCCGCCCCGCCACGCCGGAGCCCACCACGGGCACCCAGACCACATCCTCCCGAGGCTCCCCCGAGGGGCGGTAGACCAGGGGCACGTCCAGGCCCGTGGCTTCGGCGAACTCCTCCGGGGTCCAGCGGAGGGCGCGAAGCAAAGCAAATAGGCGTTCCGCTTGAAGCTTGGTGGGCAAACTGGAGCCTGTTTCTAAGGCGGAAATCATGGTTTGGGAGACTAGAGGCTCCGGTCCATCCAAAGCAGTCAGTTCTGCTAGACGCTCTTGGGTCAAGCCTAGTTCTTCGCGCCTTCTGCGCAAAGCTTCGGCCCATGGCGGCCTAGACTTAACCCTCACGGCCACGTCTCCAATGTATTGGAGAAGCATGCCCTCACTTTACTAGGCGCATCGTTACCAATGCTTGACTAATCATTAATGTGCTGGTAAGGTGTGGGTATGCAGGTCTACAGGGTAGACGAGGTAGCCCGCATGTTTAAGGTCAGCCGCATCACCGTGCTGAGATGGATAAAGAACGGCAGGTTGCGAGCCCGCAAACTAGGCAAGGGTTACAGGATTACGGAGCAAGACCTGGACCTTTTTTTGAACGCAGATACCAATGGATTGGTAAAAGGGGGTAGCCGTGATTGAGCTGGCGGCCCCCTACTTTCTCCTCGCCCTCGCCCTCTACGCCCTGCTGGGCGTCTACGTGCGGGCCCGGTACGGCCAGCCCGGGCCCGCCCTGGCCGCCGCCATGGCCTTCCTCGCGGGGCTCATGGCGGCGGTGCTGGTGGTGCTGGCCGTGGGAGGTGGAAGGTGAAGCGGGAAGCGTTCAAAGCCTTAAACGACTACCCCACCTGGCCCTCCAAGGGCTCCTGGCTCCATGCCTGGGGCCTGGACGTTTTGGGAGGCCTTCTTGCGGGGCTGATCCTGGGCCTGGCCCTCATGTTCGCCCGGGTACCGGAGGGGTGGTAGGCATGCGGCTTTTGCGGCTCAAGGAGGTGTCTGAGCGCTACGGCATCCCCATCCACGTTTTGCGGGACGCCACCAAGGCGGTGCCTACCGATCCTCGGCATCTACCTCACGTGGTCCTGAACCGCCGGGGCTCGGTGGCCACCCGCGAGGAGTGGGTGGAGGAGTGGCTTGAGCGCATGCGTTCGGACGCGGGGGTGCGCCGGGCGCAAGTGGTGGAGTGGCGGGACAGCAAAGACCTGAAGCGGTTGGTGAAGGAAGGCCCGGAGAGGCGAGCGGGAGGTGCGCGGTGAAGGAGCTTCAGCGTTATGAAAGGGCGTTGCAGATAGCTTTGGGGCGATTGGGCACAACGGGCGCGGTCCATGTGGACGGTGAAGGTGCGGTTGCCGCCGTGTTTGACCTTCACGAAGCCCTTGGAGAGACCGGTGCGGCACAGATGCGGGACGTTTACCGCCTGGTGAACGCCATTGAGGACCTGGAGCACCAGGCGGGGATCCAGCACGTGCGGGTTCGGGCCAAGGCCGAGGGGAAAGAGATCCTGGCCCGCTTGGAGGCCGTGGGCTACGAGGTGCGGCTCTTCCCCGAGATCGGCCCCCGGGATGCGGAAGTGAGCTGGATCGCCATGGCCTTTTACCAGGGCCGCCTGGTGGCCCATGCCTACGGGGACACCCGGGAGGAAGCCCTGCGGGGTCTGGCGGGGGAGGTGGGGGCGTGAAGCGCTACAGGCTCAAAGCTCTAAAGGACATAGCACGGCTAAACTTTGCCAACTTCCAGCTTTACCGGGATCCCGATGGCCCTGGCTGGATCGCTCACGGCATCCACCGCGAGTACCGCACCTTGTGGACGGCCAGGGGCTCTACCGAGCGGGAGGCGTTGGAGGCCCTACTGGGCCTTGCGCACAACGTGGGGGTGCCCTCATGATCCTGCCCCCCGACCTTCCCGAGGACGTCCGGGCTCAGGTGGAATCCCTGGCCGCCAAAAACCCCCGCTTTGCCGAGGCGGTCCTGGCCGCTTGGCGGGCCAAGCGGGAGCGGGAAGCCAAGGAGGGGGAGGCTAAGGGGGCCTCCCCCAATACTTCCACAGAGGATAGCGGTCCTAAAACCGCCGATAAGGCCCCTCGGGAGGAAGAGGGGTACCCAAGTAGCCCCCCCTCCCCTGCCCCGGCCTTTGAGGGGCCTTCCAGGCCCGCCCTGGCGGAAACCGACTGGAAGGAGGTGCGCCGCTTTGAGTGGCAGGACCTCCTGGCCAAGGCAGAGCGCACCATAGAGGCCCACGGCTACAAGGAGGTGCTGGGCCCCCTCTTCCCCCTGGTGCGCCTCCTGGTGGCCTACGCCATCTGGGAGGGGGCCCGCCTGGACCCCTCCCGGGAGGCCCACGTCTTCCTCCCCCAGTGGGAGGTGGCCCAGGCCCTGGAGGTCTCCGAGCGCACGGTGGAGCGGTGGCTCCACGACCCCCGCTATGAGAAGTACCGCCGCTACGCCCGCCACTGGATCGCCTGGGAGACCTGGATGACCTCAGGACGGGCCCTGGAGCGGGAGGGGGCGGTGAAGGGGGGCACCGTGTGGCGGGTCAGGGTGCGCCCCGTCTACCGGGCCATCCGGGTCCTGGCCCCCTACCTCCGCCTCACCTGGCGGGACCTGGAGGAGGACCGGCGGGAGGGCCGGACGGCCCGGGTGTTGAGTGCCCCCGACTCAATGTCGGGATATAAAGAGGGTCTTCTACTGGGTAAACCCCTAACCCTAAGGATCGTGGTAGGGAAGCCGTTAGCCACCTGGGAAAGCAAAAAAACCCCGTTACCATTAGATCCCGACACTCGCCGGAACTTCCGGGAACTTCTCCGGCTTTCCAGCGTCCCCGGGGGCCGGAACGGCCGCCGGAACTGGGCCCAGCAGGCGGCGTCCGCCATCGCCGCCGCCCTGGGAGACCAGAAGAGCGTGCGCTTCTGGCTCCGGGTGGTCTGGGCCGCCCTCAAGCAGGCCCTTTTTGGGGGAGGGGAAGGAGCCATGAGGGTCCTGGCCCGGGTGGTGGGCCTCGCGGCCGAAGCCCGGGCCGATGGCTTCGCCCGGAGCCCTGGGGCCTACGCCCAGGCCCTCCTGCGGCGGGAGGGGTACTGGGACCTGGTGGCCCCCTTCCAGGCCTTCAGAGCGGGGGTGCCCTATGCGGGTTGATCGGGTGCGGCTAGAGGCGGTGGCGGATATCCTCCAGCACCGGCTTCAGGAGGCCTTGGAGCAGCCTGGCCGGCGGGTCCGGTTCGTCCTCCGCACCTCTCCCAGCGATGGGGTGCAGGTCTTCTTGACCTACCGGCCTGATGGCCGGCTGGTCCTCGCCATCCGCCGGCCCGGGGGGAAGGAGGACCCTCGGGAGATCCAGGCCCTGGCCCAGCACATGGGTCTGGAGATACGGGAGGGGCCCATGGAGATGGCGGGCAGGGTACCGAGGCCAAGGGTTGGCCCCAGGAAGTACCTAGTGGCCTTCTGTGAACCTGGAAGGACGGGGTAGGATGGAGGAGGAGGAGAGAATGCAGACCCCCAGCCAGAGAGCCTTTGGACTGGCCCTCCTCCTGGGCATCGTGGCCTATTTCTGGTCCGTCTGGACTCCCAGGGTATCCCAGGCGGTTGAGGCGGAAGAGGCGGGCCCTTCCCCTGTGGTGGACCTCCAGGTGCCTCCCCAGGAGGAGTCCGGGGGCTGTCAGGGCCGCCTGACGGCCCTCTTCCGCTCCGGGGCCGAGGTGGCCTTCCACTACGAGGGGACGGCGGAAGAGGTCAGGGTGACCTGGCCAGGCGGCGAATACCGCGCCCGCACGGCGGACACCTGCACCGGCACGGAGTGCCGCTTCACCCTGCCCCGCCCGGGCATGGCGGACGTGAGAATCGCCCTGGACTCGTGCCCACCGGAGCCCGCCCCTTGACACCTAGAGGCGTGCTATGATGCGGGGGATGGAACTCAAAAAAGGGCGCCCCGGTAGGCGTATCCTGGCCCTCGCCACCCGCAAGCGGAACCCGGTGCCGATTGAGTCTCAGCCGCTGGAAAACCTCCTCTACGCCCTCCTGGGAAGCCCAGTGGCCGCCCGGTCCATCGCCCAGGCCCTGGACGGGGATATCCGCAACTTGCACGGCTGGGACATCCAGGACCTCATGGCCCTGCCCGGGGTGGGGGAGGGGGTGGCGGGCCGCCTCGCGGCCCTGGTGGAGCTGGTGAGGAGGCTCGTGAAGCGGTAAGGTTCACTTCGCCCGGGCAGTTCGCCCTGGCGTTCCGGCCCGCCGCTTCGCCCTGGCGGGCCGGGCTTTTTTTTGCCCGCCTCTGGACGGCAGGCTGAGGGCATGGCCTATCAGCGGGTGCCCGTGGACCCCAACGCCCCGTTGAAATCGGGCAAGACCTACGAGATCGTGGCGGCCCACAAAGGGGGGGACGTTTCCCGGGTCACGCGGGCCGATTTGGAGCGGGCCCTGCAGGCCAAGTACGGCCCTGGGGTCCGGGTGTTGGACTGGGGGAAGCGGGGGAATGACCTGGTGATCCGGTTGAAGGTGGAGGCCACGTCTTCCTCCGCCGGAACCTCTGACCCCTGGGCCGTGCCTCCCGCCTACGGGGGGGCGGGATGCGGGTCCACCAAGTGCCCCCAGCCCATGGGCTACATGGGCGGGGGGGACATCTACCCGGCCTTCCTGCCCGCCCTGGCCCTCAGCGCCGCCGCGGTCATCGCCGTCCTCTATCTGGTGTGGCGGATCGTGGCCGAGCTGAAGGAGGCGGTGGAGCTGGTGCCGGCCCCGGCCCGGGCGGCCGCCGTGGCGGGCGCGGGGGTGGGCGTGGGGGCCCTCGGGCTGGCCGCCCTGGGTGTGGTGGCCCTGGCCCTTGTTGGTGGAAGGAGAAGGAGGGCGTATGCCTAAGCGGAAAACCAGGAAGACCAAGAAGAAGCGCTCTCGGAGGTAGACCATGCTCCGGCTCAAGCTCCCGGAGGAGGTCGTAGGCGAGAAGGCCGTCCTGGAGGAGGAGGGGGAGGCCAAAGAGGTGAAGGCCGTCCCCCTCCAGGGGCCTTTAGACCCCATTCTGGAGGCCGCCGTGGAGTCCCAGCCCCGGGTGGCCGGGCCTAAAGAGGCCTCGCAGGAGCCTACCGGGCCGGAACCCGAGCCCGAGGAGCCCCCCAGGGGCGCCCCTAAGAAGAACCCCTTCGGCTTCCTCGCGGCCCTGGGGGCCGGGGCCCTGGTCCTCCTGGGCGTGGCCCTGGCCGGAAAGGGAGGTGCGAGTGCAAGCGGTAGTGGAGGAACAGGCGCAAACCCCACCCCCACCGCCCCCGGTGGAGGAAGCGGAAGCGGCCCCGTCATCTGGTAGCTGGGAGCCCCTAGGCGAGGAGGACCTAGGGGACTTCTCCGAGCTTCCGCCGGCGGAGCCTCCCGTGATCCCCTTCACCGGGGAGGAGATCGCGGGCGGGGCGGCGTTTTTGCTCATGCTCGGGGTGCGGGTCCAGTCGGAGGAGGAAAAGGCCGCGTTTCTGCGGGCTTGGCAGGGGGCCCTCTTCGGCCTCATGCCCCCGGCCCAAGTGCTGGACGTCCTGAAGGTCGGGGAGGCCCTGGCCCAGTACGGCATCGGGAAGAACCGCGTTCCGGGCATGGGGAGCGTGGAGAATCTTCCCCCGTGGCTCAGGATCCTTCTGGGCGGCGGAGTGCTGGCTATAGCGGCGTACGGAGGTGTGCGTGCGGTTATGGATGTACGGGCTTCTAGGACTGCTGGGGGTGCTCCTGATGGTGCGCCGCCAAGCGCCTAGTGCCTACATCGTCCTGGACCCCGGCCATGGCGGGCAGGATCCCGGGGCTGTGGCCCCGGACGGCACCCGGGAGGCCGATTTGAACCTGGCCCAGGCTCTCACCCTGAAGGAGTACCTGGTGGCCCTGGGCTACCGGGTGGGGTTCACCAGGACCTCGGACGTCTATGTCCCCCTTTCTGAGCGTATTGCCATGGCCCGGAGGATTGGGGCGAGGCTCTTCATATCGGTCCACCATGACACTCCCACGGCCTCGAGGCCCGGGGTCTACTACTCCCCTCATCCGGGATCCGAGGAGTTGGCCCGCACCGTGGCCGCTGCCTTGGGGGAGGGGGCATGGGTTAGGCCCTCTTCGGCCTCGAGGTTCGGACGCCTCTACATAGACGACTTCCCCGGCCCGGCCATCCTGGTGGAGTTCGGCCCCACGCGGCCCATCAGCAGGGCAGAGAGGATCGCCCGGGCTCAGGCCGTAGCCTCTCCGATAGCTGAGTTTGCGAGGAGGTGGACGGCGTGAAAGAGCGGTGGATCCAAAACGCCATCACGCGCCCCGGACGCCTCCGGGCCTACGTGCGGCGGGTGTACGGGCAGGCGGGTTTTACGCAGCGGGGGACGATCCGAATGGAAATTTTGCGGGAGCTGGCCAGGCGTAAGGACGGCATAGGCAGGGCGGCCCGCTTGGCCATCACCTTGAGGAGGCTGAAATGATCCGCAGGCAAACCATTTGCCGGGTGATCTATCGGGATGCGAAAGGGCGCTTCGTCCGGCCCCCGGAGAAGCCCGCCCGGGTAGAGCTTGAGCCCCTGCCTAAGGGAGAAAAGGGCCGCTTCCGGGTGCATAAGGGCGGTGAGGTGGTGGCCGTGGAGGAGATGCCCAGGGGCAGGGGCGTGCGGGTGCGCTTTGTGCCGGACGCCTCTATCCGCAAGGCGATGCTCGAGGCTCGCGCCCGCGGGGACAAGGCCACCCTTCGGCAGATCCGGGAGTGGGAGCGGGAAGTGAAGCGCCTGGCGGCCGAAGACTACCTGAAGGCCAAGCGATCCAAGGAGTGGGCTAAGCGGATGGAGCGGGCCAAGCAAAAGAGTGATGCTTCCAAAGGGGGGAAAAAGGCGGCTGCCAACCGCCGAAAGGTCCAGGCCCTCGCGGAACGGATGCGTGGGGAAAGCACATCTGCGCTCATGGCCCGCTACCGGCGCGTGGGAGGGGACGACCTGGAGAAGAGGGCTATAGCAGAGGTGCTTAAGGAACGCGGTTTGAACGTTGAGCAACCCAAGCGCAAACGGAGGAGGAAATGATGGAGTTCGCCCAAAAGAACGCTTTCCCATTAGCGGTTTTGGCGGGAGGCCTCTACCTGGGCCTCGGGCGCGTGAAGAACCTGCGGGAGGGCAAGGGCTGCCCCAAGTGCGAGACCGTCCAAGCGGTGGTGGCCTTCGCCCTGGCCGCCTGGGCCGGGTGGGAGCTGTGGCAGGCCTACCGGGGCCAAGCCTAAATGGGCGGCAGGCAGACCTTCCGCATCCTCATCGTGGGCAAGTCCGGGTCAGGGAAGTCCACCCTGGCCCGGCAGATCGTGCGGGCTATGGAGGGCCGCTTCCGCCGCCTCGTCATCGTCAACCGCAAAACGGAGTTCGGTGATTTGGCAGAGGCCCGTTTCCGCGTGGGGGAGGACGGGGACCCCTGGGCTGTTTTGAAGCGCCACCGCAGGGTCCACTTCCACGTCACCGGCTACGACCCCCGCCCCTTTTTGGATGCCCTGGGCCAGGCCATCATGCGCCTCCAGGACACCCTGCTGCTGCTTGACGAGGCCCACCACTTTTTTCCCCGGGGGCAGGTGCCCAAGGGCCTCTTTGAGGTCCTGACCGGGGGAAGGGAGCACGGGCATTCGGCCATCTTCGTCACCCAGATGCTCCAGGCCGCCACCGGGGGCATAGACCCCGGGGTGCGCCGTCAGGCCTCCCACCTGGTGGCCTTCCGCCTCACGGAACCCCGGGAAGTCCAGGCCCTGGCGGACATGTTCCCCGAGCTGGGGGAGCGGGTCAGGCTCCTCAAGCGCCCCGATGACGGCCTGCCCCCGGAGTACGGGGTGAAGGACCTTGATCGGGACCAGGCGGGCCTGGTCCTCCGAGACCCGAGGGCCCCACAAAGGCGGGTTTTCGTGCCCCTGGACGGCTAAGGGGCACTTCGCCCGGGCGAAGTGCCCGGGCGAAGCGGCCCAAAACTCCCAAGCGCCCCGGCGTATCTCCGGGGCGCTTCGCTCTTTATTCCCCCATCGCCCCCCGCCTACCGTGGGCGGCAGAAGGAGGGCGAATGGCGGATACGGCGGCAATCGCGGCGCAGGACATGCGCAAGCTGGCCTCCACCAGCAACCCCCTGGAGGTGGTGCAGAACCCCATCGTGGTGAGCGTGAGCGTGGGGGTGCTGGGGGCCTACTTGGCGCGGAAGGCGCTCTATACGTCCAGGCGCGACCTCTTTGGCTGGGCGGCGAAGGGCGAGGACGGGCGTGTCCACTACTACGCGGTGGGTCCGGACGGAAAGCCCGACACCAGCAAGGAGGTCCCGAACGCCCGGACCAACAGGGTGTTGCTCAACCTGGGCGGGGTCATCGTGGGCTCACTGCTCATCAACAACAAGCTGACCGAGGACCCCATGGTGGACTACATCGGCTTAGGCGTGGCGGCCGGTTCCTTCGCGAACCTGGTCATGGCGATTTTGGACATTGACTAAGGAGGTAAAGGATGCAGGAGGCTTTTGAGCGGATCAAGCGGCTTCGGCCCGGGGCCCGCCCCATCACCATCCTGAGGAGCGGCCCCGAGTTCCAGGCGTACGGCGGCAGGCAGAAGGTGAAGGTGGGCGAGTTCGTGGTGCCCTCGGGGGCCACTTGGGTCTTTCCCAACCCCGTCCCCGTGGTCCTCAAGCTCTACGATTCCAACGGCAACCAGCTGCCCCACACCACGGACGTCTTCTTTGCCCGGCGCACCAAGGGCTTTGACTTCCCCGAGTTTTTGGTCAAGGCCCAGTACGCTTCGTACTACGACCTCTCCGAGGCCCAGCAGCGGGACGCCAAGTTCTACCAGAACATCCTGCAGACCGCGAGCCCACTTTACGCCCCTACCCCGCCCCAGGGCATCGTGCTGCGGGAGGGGGACACCCTGGAGATCTACGTGGAGACCGACCCCGGCATCACCGTGAACCTCAACGACTCCCGCACCCGCATTGAGCTGCCCGTGGGCGTGGACAACTCCAACGTGTAGGAGGGACCATGGCGCTCTTGGACAGCCTTCGCAACGCGGTTCGGAGGGGTCTCGGGGTGTTCCAGGACGCCCCGGCGGCCCCCTCCCCTACCCCTCAGCCGCAGCCCCAGCCGGCGCGGCCCGCTCCGGCGGCGGTCCAGGCCTCGGGGTGGCAGTTCGCGTGGATTGACAACGAGGACTTTGACGCCACCGGCCTGGCCTACCGCCCCAATGAGTATTTCGCCCTGGCCCAGATGCGCACCCCGGACACGGCCCACTTCCGCATCCTGGCGGGAGAGCGGCGCCTGCGTATCTACCTGAAGGGCCTGGCCGCCTTCGCGGGCCAGAATCTGGCCACGGCCCAGGCCCGCACCGTCACCCTGCCCTACCTCATCCCCTCCTTGCAGGGGGCCCCTACCCTGCCCTCCACCTACCACCCAGACGTGGCCGTCTGGGCCAAGGTGGGCGGGGTGTGGCAGCGGTGCCAGATCAATGCCGTCAACTACGCTGGCCAGCAAGTGACCTTCGTGGAGCCCGCCGGCGTGACCGGCACCCAGGACATTGAGGTCTACTACACCCACGCTGACGGGCAGTTCCGCCTCCGGGTGGCCCGGGACGCGGGCGGGGTGGACGACAGCGTGGCCACCGTCTTCAACCAGTCCTTCTCCACAATGCACAGCGTGGACCAAAACAACCTGGAGACCATGCTGGCCTGGCCCCAGCAGGTGGAGCTGGTGCCGGGCACCCGCCTTCTCCTGGAGATCTTCACCACCCAGGTGCCCATGGTCTGGAACGAGCGGGCCGGCCACTACATCCAGATCGCCGCCATGGGCCGGCGGGTGGAGGTGCTGGACAAGGGCCGCCTCTTGCGCCTGGCTGAGTTGGAGAACCGGGGCGGCCTCTGAGGGGGGTGAGCCGTGTCGTTCTCCACGTCCCAATATTTGTATGACGGGCTCTACTCAGGGTCCTCAGGGTCCTCCAACTTCGGCCTCTCCAACTCCTACACCCTTCCCCTTACGGGGGGCGTTTCCGGGAGCGCTGGAGACACCCCCCTCTGGGCCCAGATCTTGGGCGGGCTGGGCCAGATTGGGAGCCTCATTGACCCTTACATCTTGACCGAGCAGGAAAAGCTGGAGTACCAGCTTCGGCTGGCTCAGGCCCAGGCGGAAGCGGCCAAAGCACAAGCCGCGAGCGTCCAAGCACAGCCCGTGGTGCCCGTGTGGGTCTGGGTCCTGGTGGGCCTCGGGGTGGTCCTCCTGGTGGTCTTTGCATTGAAGGAGTGAGCATGGACGTTTTTGGCGGGCTCATCGGTGGGGTCACCAACCTGCTGGACGACTTCATCTTCACGGATGAGGAGCGCATGGCCTTGGAGGCCCAAAAGGCGGCCGCCCAAGCCCAGCTGGAAGCGGCCCGCTTGGCCCAAGAGCGGGCCATGTTGGAGGCCGCCGCCCGAGCCCGCCAGGCCCAGGCCCTCACCGTGGCCGCCGTCACCGTAGGAGCGGCGCTGGTGATGGCCGTGCTGGTTTGGAGGTGGACATGAGCGAGAACATCCTTTTGGGGGTTGCGGCGATAGGAGCGGTGGCCGTGGGAGGACTCATCGCCTGGAGGATGACCGATCCCAACAGGCAGCGTGTGCCGTACGCCCCGGCCCAGCCTGTCGTGCCCCCCTCCTCTCAACCGGTTTTGCCTCCTTCCTCTCAACCCATTTCTACCCCGACCCCTCCGCAGACTTTCCCAACGTTGCCCAATCCCATTGCCACTCCCACCCCAACTCCTACCCCGACCCCCCAAACCCCCACCATCACCAAGGGGCAGCTTTGCGCGGACCTGAAAGCAAAACTGCAAAAGCTCCAGTCTGCCGCGGACGATGTGAAGAAGAAGATGAACGACCTGGTGGCCAAGGGGTCCAGCGCGGATACGAACTGCTGGAGCTACGCCAAGCGCGAGGCGTGCTTCTGGGAAATCTGCTCCCCTGCCCTGTGGGGCAACTACAACGCCTGCATGGACTACGTGAAGGGGCAGGGGCCCCGGCCGGGAAATCTCTTCAACTACGACGACTCCCGGGCGGTAGACCAGGCGGCCCAGCAGTACGCGGCCCTGAAAGGCGAGCTGGAGACCTACCAGGCTCAGATTGAGGGGGTCAAGAAGCAGCTGCAGCAGCTGGCCACGGAGGGGGTGGTCTGCTGATGGAGTGGAAGGACGTCCTGGACATGGGCTTGGGGGCAGTGGCCTTTGCGGCGTTCCTGAAGCTCGTGTTCCGGGATGTGGCCGAGGTGCGGGAGCGTTTGGCCCGGATAGAGGAGAACGGCCGCCGGCAGGCCTACTACCTCTCCCGGGTGGCGAACGCCATGGAGGCCCAGGCTTATCGGCAGGGCCTTCGGGTGAGAGAGGTGAAAATGGAGGTGGAAGGGGATGGAAAGTAGAGCGCTTTTGCTGGCCCTTTTGGGCTTTGGCGTGGCCGGCTATCTGGCGTATCAGCTGGCCAAGGGGCAGGGGCAGGCTACCGCCGGGCAGACGCCGGAGCAGTCGGAAGCTCCCCCGGCCCAGACCGAAACCCCTCCCGTGGTGGTGGGTGACTTCGGCGGCCAGCTGCCCTTTGGGCTGGGCGGTTTGGGGCAGGACGCCCTTTGCCGGGTAGCCCCGAGCCTCTGCGGCTGGTACAACCCGGCCTATGTGGGCAGGCCCGCCCCTCTGCCCGTGGTGCCCCTCTGGTGAGGTGACGGATGCAGGGCGCTTGGATCGTGGCGGTGGCGGTGGCGGCCGGGGCCTACGCGGGCTATGCCCTGGCCCGGCGGGGAGGGGGGCAGTCCCAGGGCGGGCAGCCTTCCCGAAGCTCCCCCCCGTCTGATCGGATCTGCCCGCAGGTGCTGGTCACGTGCCAGGACGGATCTCCTGCTCCCACCCCCTGCGATTGCGAAGGTAGGGGTGGGGTGAAGCGCGTGGGGGTGATGGTGTGAGCGTGCAGGACTTCCTACCTCAGGGGCAGGTCTGGCTCGTCTGGCTCGTCCAAGCTCTCCTCGCGGCCGGGCTCATCGCCCTTCTCTCGGGGCTCATCGTGCGGGTGGTTTCCCCCATCCCCGTGGTGGGGCCCGTGCTCGCGGCGGCGGTGCGCATGCTCTTTTCCAACTACGAGAAGTGGCTTTCCGAGCGTGTTCCCAAGCTGGCCGAGCAGGCGGTTCTGGCCACGGAGGAGAAGTGGCGGAAGGTGGGGAGTCAGTACGACCCTGCGGCCCGGGCCCAGGCCAAGCTGCAGGAGGCCATAGAAGCCCTGCAGCAGATGGCCCCCGGCCTGCCCCGGGACATAGCCCAGAAGCAGATTGAGGCCGCCTTGGCCCGCATCCGGGCCATGGGCATGGAGCAAAAAGTGGGAGGTGGGAAATGAGCTTTGGTGATGGCCTTCGCTTCGGTGCCGGCTTCGTGGTGGGGGGCACCCTCATCTGGGTAGGGGTGCTCCTCATCCTGGCCCTGATTGGTGCGGTGGTAGGCGGTGGCGATGGGCGAAAAGGTTGAGGTGGTCCAGAACCGGGTGAGCCTCTGGCAGGCCTACAAGCAGGGGGTGGGGGTGGGCCTGGGCATCCTCACGGTTTACGCCCTGGCCCTCCTCCTCCTGGGCTTCCTGGCCAGCCGGGCCCTGGCCTCGGCCCCGAGCGGGGGGAACGAGCCCCCGAAGAACGAGGGAGGAAAGGCATGCTCAACCTCTTGGGTGTGAAGCCTGAGGACGTGCAGAACCTGGTGCGGCAGGGGCAGGCAGCGCTGGATGAGCTCCGGGCTGAAATGGCCTGCGTGAAGGAGTCCCTGCAGGCCATAGAGCGGATCCTGGGCTACGAGTACGGGCGCCCGGCCCGGGGTCTCATGGGGCACGATCCATATCGCCTTCCCCTCATCGCGCAGGTGGACGCCGGGGCCCAGCCCACCAGGGTGGACCTGGCCGGGCTGTTGGGAAAGCTGGCTACCCGTGGTCACGTGGTGAACATAGGGGACGCTAAGGTGAGGATTTGGTTTGTGTCTGGGGCCCAGCGGGTGGGGCCCTACATCCTCCTGCCCTCGGCGGCCGTGGAGCTCAGTTTCGCCTTGGAGGCCCTCGAGGTGGCGGACGCCGGGGAGGGCCCGAGTCGGGTTCAGCTCTTAATGCAATGATTCCTGCCCAGGTTGCCAAAAGGGGTAAAGGCTTTTTCCCCGAGGTGCGGTATAGCCGGGGTCCCCGCGTGATGGGGCAGACCGGGGATAACTCTTTCCGCGCCCTCTTGGGGTACCTCTGGATGGCGGTCCTGGACCGGGTGCAGGGCTTCCGCCTCTTCCAGGCCCAGGTGCCTGGGGAGGGCCCCTGGGCTTTGGACGACCCTCGAGGTCCGGACGTGGCGGAGTGGGTGGAAGTGCCCGCGCCCCCTTTGCCCCACCCCCACCAGGAGGTGCGGCACATCGCCCTTTGCTTTGACCAGGCGGCCCGCCACGTGGTGGCCTACGAGTACCAGGGCCAGGTGTACGTGCGGCAGTGGGATCCCGTCTCTCGGGAGTACGTGATGCGCGGGCCGTGGCCGGGGGTGGACCCACTCGTGATTTGGGACTTTGAGGTGGGCTACTATGTGCCGGACTCGGACGTGGTTCTCCTGCACCTGTCGCCCGACCGCTCCACCCTGGTTTACCGGGTGCAGCGGGAGCTGTACGCCACGGCTCGCGAGGTGCCCCTGCCCGGGCCCGCCTACCTGGACCAGGCGGTGGCCTTGCCCTATCAGTTTGAGGCGCTGGGCTCCTTCACTGCGGACCCGGACGCCTCCGGGGTGGTCCTGCGTTCGGACCTGTACCCCGTTTACGTGGGCGAGACAGCGGGTAGCGCGGGCTTCGCCGCCCCGGTCGCTTGGGACCTCATCCCCGTGGTGGTGGTTCGGGATTTGGGGGGCGAGTCTGCGGGCTCTGTGGGGTTCTCTGCCCCGGTTGCGTGGGACCTCATCCGCGAGGCTCCCGTGGTGGTGGTTCGGGATTTGGGGGGCGAGACAGCGGGCACTGCGAGCTTCGCCGCCCCGGTCGCGTGGGACCTCATCCCCGTGGTGGTGGTTCGGGATTTGGGGGGCGAGACAGCGGGCACTGCGAGCTTCGCCGCCCCGGTCGCTTGGGACTACAGGCTGGTGGTGGTGGTTTATGACGGGGGGGCAGACGTGGCCGCCACGGCCGCGTTTTCCGCCCCTACGGCCTGGAGCTACGATCCAGCCTAGGAGGTGCGTATGGGACGAATCTTGCTGCCCAGAATTTTGGTGAGGCCTCTACTTCCACCGGAGCCGATCATGACCGCGCGCATCCAGCCGCAGCACATGCATTGGCAGGTGGGGCGCTACAGGGAGCGCCTACGCTCGGGCCCGGGTGGCCTGGGGAGGGGACGGGTTTGGGTCGCGGAGCGCGAAGGGGAGCAACACAACCTAATCCTCAATCAGTTCTACGATGCCCTCATTCCGTCCTATGGGCTGTTGGGGCCGTCCCAGTACGCTGTAGTGGGCACGGGCAGTACAGCTCCCAGTCCCACCCAAACTGGGCTGGTTAGCGAAGTCGCCCGGAGCAACGCGGTGCCGAGCGGGGAGTCAAACCAAGCGATTTACATCAGCCCCGGGGTGTACGACATCAAGCGTGTATATGAGTTTGGAGAAGCTCAAGTGGGGGGCCGGAACCTCACCGAGTGGGGATTTGGGCCCGTGGCCGCGGCTGGCGGCAACCTCATGACCCGGGAGCTGTTTAGGGACACGAACGGAACCCCAGTGGTGCTCACCCTGGCTTCGGACCAGCGTCTGCGGCTGATTTACAAGTACCGAGTCACGCTGGGGCCCACCACCCCTCAGCCCGTGACCGTCAATATCAATGGAGTGGGCCCTCGCACGGCCCAGTTTATAGTGACAGGCAAGCTCGGCGGAAGTGGTGCTCAATCTTACTCTACTTCTGTATCCGGTGTGGATTTTTGGGGTGGCCAATACTATGGCGACTTGATAGTGGCCGATTTTGCGTCTCGTGGCGTGGGCACACAGGGCGGTGTAATGCTGGTGAACTCCGCAATGCCGCTAACGTATTTGCATAGTGGCCAAGTGTCTTCCAACGGCCCTACCCCCACGTATGAGCCCCCGGTGGGGCGTTCTAGAAGGTGGAGCAGACTCTATGCTCCGGACGAAGCCAACATGACGATTGTGAGCGTGGTGTTAGTAACGGCAGTTGGCTATTCTTCGGGACCAACCGTCAATCTGGTCTTTGACAGTGGCCAGGCAATTACCAAGACCAACCTCTACAAGCTCCTCATCGGCTACTGGACATTAACGTGGGGACCATGATTCCGAAATTGACGCTTAGGGATGTTATTGTGCCGCCCCCGGTGCCCGCACCCCTGCCGGGGGCCTCGGTGAGCCCGCCGGCCAGGCGGTCCTTCCAGCACGTGTCGGGGGCGGTGGTGGGGGGCCGGGTGGACTACCGGGATCTGAACGCCTTCGCCTGGTATGTGGCCGGCGGCTACCTCACGCTCAACCGGGGTCGGAAGCGGATCGGGAGGACGTTCCGTGGCGCGGAGGACGGGCGGAGGGAACGGCGGTAGCTGGGCCCTTTGGGGCCTCGGGGCCCTCGGGCTGGCCCTTGCGGTTGGGGCCGGGGCTAGGGCGGGGGCGTCCTCAAGAAGCGGGGGGGCGTCCTCGAGGGCGGGGGGCGTCCTCGAGGGGCGGGGGGCCGTCCACGGGATGCCCGTATCCACCGGCAGGGCCGCCTGCCTTGGGCAAGGGGCGCTGGGACCTTATAGACCGCATCTATGCCCGCATCTTGGAGGCCAATCCAGCGCTAGGGAGGCAGTCCTGCCCCGATTGCGGGGGGCGCACGATAGCTCATATCGTGGCTGGGGCCCTGGCCCAGGCAGACGGAATGGGGGTGCCCGTGGACCTGGTGACGGCCCTGGCCCGGAGAGAGAGCACTTTCAACCCCCACGTGGACCGGGTAGCCTACGCTTTGCAAATCAGCCAGAACGGCGCAAACTGCGCCTCGGGCAGTGAGATCGGCCCCCTGCAGGCGAAACCGTGCGCGTTCCGGCAGGTGGGCATGGATCCCGCCCTGCTCCTCAACATGCCCTTTCCTGCCCGGGTGCAGTACGCCACGGCGGCGGGGATCCGCTATCTGGCGTGGTTGAAGGGGCAGTTTCCCACGTGGTGCGATGTCCTGCACGCCTACAACCGGGGGCCTACCGCTTATAGGCGGGGTGAGCGGAATGACGCCTATGTAGACCAGATCCTGGCCTGGGCGTCCCAATACTCCGAGCTGAGGGTATGA

Protein sequences of DBSCAN-SWA_2

>LR027517|1406302:1429904|1418576_1418972_+|VCU53792.1|DBSCAN-SWA
MLRLKLPEEVVGEKAVLEEEGEAKEVKAVPLQGPLDPILEAAVESQPRVAGPKEASQEPTGPEPEPEEPPRGAPKKNPFGFLAALGAGALVLLGVALAGKGGASASGSGGTGANPTPTAPGGGSGSGPVIW
>LR027517|1406302:1429904|1420103_1420691_+|VCU53796.1|DBSCAN-SWA
MIRRQTICRVIYRDAKGRFVRPPEKPARVELEPLPKGEKGRFRVHKGGEVVAVEEMPRGRGVRVRFVPDASIRKAMLEARARGDKATLRQIREWEREVKRLAAEDYLKAKRSKEWAKRMERAKQKSDASKGGKKAAANRRKVQALAERMRGESTSALMARYRRVGGDDLEKRAIAEVLKERGLNVEQPKRKRRRK
>LR027517|1406302:1429904|1429355_1429904_+|VCU53813.1|DBSCAN-SWA
MGKGRWDLIDRIYARILEANPALGRQSCPDCGGRTIAHIVAGALAQADGMGVPVDLVTALARRESTFNPHVDRVAYALQISQNGANCASGSEIGPLQAKPCAFRQVGMDPALLLNMPFPARVQYATAAGIRYLAWLKGQFPTWCDVLHAYNRGPTAYRRGERNDAYVDQILAWASQYSELRV
>LR027517|1406302:1429904|1424809_1425046_+|VCU53805.1|DBSCAN-SWA
MEWKDVLDMGLGAVAFAAFLKLVFRDVAEVRERLARIEENGRRQAYYLSRVANAMEAQAYRQGLRVREVKMEVEGDGK
>LR027517|1406302:1429904|1409524_1410499_-|VCU53776.1|DBSCAN-SWA
MDGNAPEPRYWEKMRLVAEVLKAVEGPIYIATHVDPDGDAIGSSLGLYRALKALGKEAYWVADPPRFLRFLPKEEEYSDPVEKLPPGATLVALDSAEPSRVVGVPVEGFVINIDHHGTNPRFGHLHVVDPSKAATAQMVKDLIDLLGVEWTAEIATPVLTGILTDTGNFRFANTTPEVLRVAAELLGYGVKLAELTDRLQFRPPSYFRLMGKVLSTVAFHFGGLLVTAHLPEDAGAEEDSDDFVGLIRYVEGSVVSVFLRKREEGVKVSIRSRGGVSAQNIALKLGGGGHVPAAGATLKGLDLDQAYERVLEAVKEELTRAGYL
>LR027517|1406302:1429904|1414651_1414939_+|VCU53784.1|DBSCAN-SWA
MRLLRLKEVSERYGIPIHVLRDATKAVPTDPRHLPHVVLNRRGSVATREEWVEEWLERMRSDAGVRRAQVVEWRDSKDLKRLVKEGPERRAGGAR
>LR027517|1406302:1429904|1420885_1421566_+|VCU53798.1|DBSCAN-SWA
MGGRQTFRILIVGKSGSGKSTLARQIVRAMEGRFRRLVIVNRKTEFGDLAEARFRVGEDGDPWAVLKRHRRVHFHVTGYDPRPFLDALGQAIMRLQDTLLLLDEAHHFFPRGQVPKGLFEVLTGGREHGHSAIFVTQMLQAATGGIDPGVRRQASHLVAFRLTEPREVQALADMFPELGERVRLLKRPDDGLPPEYGVKDLDRDQAGLVLRDPRAPQRRVFVPLDG
>LR027517|1406302:1429904|1425035_1425338_+|VCU53806.1|DBSCAN-SWA
MESRALLLALLGFGVAGYLAYQLAKGQGQATAGQTPEQSEAPPAQTETPPVVVGDFGGQLPFGLGGLGQDALCRVAPSLCGWYNPAYVGRPAPLPVVPLW
>LR027517|1406302:1429904|1408998_1409547_+|VCU53775.1|DBSCAN-SWA
MIRHRLSLEEFQALLEKAPEGLRLELLDGEVYEMAPIGSGHASLVTYLTKQLERLYGDRALVYVQNPLRLSPHSLPQPDLALLRPREDFYRERLPEAGDTLLVVEVSFSTREMDLKKLALYAQGGVPEVWLVEEGGSLEVYREPRGNRYRHRLLVEPGEEVAPLLLSHPPLLWDPPRGTPPA
>LR027517|1406302:1429904|1419346_1419916_+|VCU53794.1|DBSCAN-SWA
MYGLLGLLGVLLMVRRQAPSAYIVLDPGHGGQDPGAVAPDGTREADLNLAQALTLKEYLVALGYRVGFTRTSDVYVPLSERIAMARRIGARLFISVHHDTPTASRPGVYYSPHPGSEELARTVAAALGEGAWVRPSSASRFGRLYIDDFPGPAILVEFGPTRPISRAERIARAQAVASPIAEFARRWTA
>LR027517|1406302:1429904|1414490_1414649_+|VCU53783.1|DBSCAN-SWA
MKREAFKALNDYPTWPSKGSWLHAWGLDVLGGLLAGLILGLALMFARVPEGW
>LR027517|1406302:1429904|1421700_1422117_+|VCU53799.1|DBSCAN-SWA
MADTAAIAAQDMRKLASTSNPLEVVQNPIVVSVSVGVLGAYLARKALYTSRRDLFGWAAKGEDGRVHYYAVGPDGKPDTSKEVPNARTNRVLLNLGGVIVGSLLINNKLTEDPMVDYIGLGVAAGSFANLVMAILDID
>LR027517|1406302:1429904|1420687_1420885_+|VCU53797.1|DBSCAN-SWA
MMEFAQKNAFPLAVLAGGLYLGLGRVKNLREGKGCPKCETVQAVVAFALAAWAGWELWQAYRGQA
>LR027517|1406302:1429904|1427842_1428928_+|VCU53811.1|DBSCAN-SWA
MGRILLPRILVRPLLPPEPIMTARIQPQHMHWQVGRYRERLRSGPGGLGRGRVWVAEREGEQHNLILNQFYDALIPSYGLLGPSQYAVVGTGSTAPSPTQTGLVSEVARSNAVPSGESNQAIYISPGVYDIKRVYEFGEAQVGGRNLTEWGFGPVAAAGGNLMTRELFRDTNGTPVVLTLASDQRLRLIYKYRVTLGPTTPQPVTVNINGVGPRTAQFIVTGKLGGSGAQSYSTSVSGVDFWGGQYYGDLIVADFASRGVGTQGGVMLVNSAMPLTYLHSGQVSSNGPTPTYEPPVGRSRRWSRLYAPDEANMTIVSVVLVTAVGYSSGPTVNLVFDSGQAITKTNLYKLLIGYWTLTWGP
>LR027517|1406302:1429904|1423540_1423906_+|VCU53802.1|DBSCAN-SWA
MSFSTSQYLYDGLYSGSSGSSNFGLSNSYTLPLTGGVSGSAGDTPLWAQILGGLGQIGSLIDPYILTEQEKLEYQLRLAQAQAEAAKAQAASVQAQPVVPVWVWVLVGLGVVLLVVFALKE
>LR027517|1406302:1429904|1415563_1416814_+|VCU53787.1|DBSCAN-SWA
MILPPDLPEDVRAQVESLAAKNPRFAEAVLAAWRAKREREAKEGEAKGASPNTSTEDSGPKTADKAPREEEGYPSSPPSPAPAFEGPSRPALAETDWKEVRRFEWQDLLAKAERTIEAHGYKEVLGPLFPLVRLLVAYAIWEGARLDPSREAHVFLPQWEVAQALEVSERTVERWLHDPRYEKYRRYARHWIAWETWMTSGRALEREGAVKGGTVWRVRVRPVYRAIRVLAPYLRLTWRDLEEDRREGRTARVLSAPDSMSGYKEGLLLGKPLTLRIVVGKPLATWESKKTPLPLDPDTRRNFRELLRLSSVPGGRNGRRNWAQQAASAIAAALGDQKSVRFWLRVVWAALKQALFGGGEGAMRVLARVVGLAAEARADGFARSPGAYAQALLRREGYWDLVAPFQAFRAGVPYAG
>LR027517|1406302:1429904|1415357_1415567_+|VCU53786.1|DBSCAN-SWA
MKRYRLKALKDIARLNFANFQLYRDPDGPGWIAHGIHREYRTLWTARGSTEREALEALLGLAHNVGVPS
>LR027517|1406302:1429904|1417570_1417864_+|VCU53790.1|DBSCAN-SWA
MMRGMELKKGRPGRRILALATRKRNPVPIESQPLENLLYALLGSPVAARSIAQALDGDIRNLHGWDIQDLMALPGVGEGVAGRLAALVELVRRLVKR
>LR027517|1406302:1429904|1417146_1417554_+|VCU53789.1|DBSCAN-SWA
MEEEERMQTPSQRAFGLALLLGIVAYFWSVWTPRVSQAVEAEEAGPSPVVDLQVPPQEESGGCQGRLTALFRSGAEVAFHYEGTAEEVRVTWPGGEYRARTADTCTGTECRFTLPRPGMADVRIALDSCPPEPAP
>LR027517|1406302:1429904|1419912_1420107_+|VCU53795.1|DBSCAN-SWA
MKERWIQNAITRPGRLRAYVRRVYGQAGFTQRGTIRMEILRELARRKDGIGRAARLAITLRRLK
>LR027517|1406302:1429904|1426756_1427833_+|VCU53810.1|DBSCAN-SWA
MIPAQVAKRGKGFFPEVRYSRGPRVMGQTGDNSFRALLGYLWMAVLDRVQGFRLFQAQVPGEGPWALDDPRGPDVAEWVEVPAPPLPHPHQEVRHIALCFDQAARHVVAYEYQGQVYVRQWDPVSREYVMRGPWPGVDPLVIWDFEVGYYVPDSDVVLLHLSPDRSTLVYRVQRELYATAREVPLPGPAYLDQAVALPYQFEALGSFTADPDASGVVLRSDLYPVYVGETAGSAGFAAPVAWDLIPVVVVRDLGGESAGSVGFSAPVAWDLIREAPVVVVRDLGGETAGTASFAAPVAWDLIPVVVVRDLGGETAGTASFAAPVAWDYRLVVVVYDGGADVAATAAFSAPTAWSYDPA
>LR027517|1406302:1429904|1410669_1411842_-|VCU53777.1|DBSCAN-SWA
MKRKRGRGEGSIFRRKDGRWAGFVTLGRRPDGRQVKKWVYGRTRQEVAEKLARLLPQAWTGTIPDAGRLKLGDWLLHWIEERTTRKALRPTTVRNYRVYLGHLDPVLHTPISRLTALQLRALFQGLAYLSPSHRRHIYQFLRAALRDAVRADLIPSNPMDAVDPPEGGPVRPARAWTPEEVTRFLEASKEHRLFPLFALMLATGLRIGEALALRWEDWEGDVLHVRHTLRRDGTLGPAKTPGSVAPIYLDPDTQALLAWWRERLEEEKASTPDWQDHGLMFPSSKGTPLEYNNFKRAFYALQEKAGVSRITPHGLRHTYTSLALRAGLPPKVVAARLRHKDVKLTLQVYQQLMNEDLKEAALPLDTLLHLQNRNKRDRSASKAGRKKALQ
>LR027517|1406302:1429904|1412893_1413358_-|VCU53779.1|DBSCAN-SWA
MKPSGIRWGLVVFGLVLAACSSNPPINATGTWLDLTAKTRPLNKADCPEDPINTGELRFSLNQSGSNVSGTVRAYTPGQPAAYGDVTAQIRQDGTINGNMVFSSQSGNSVISIAFEGRIQGTYFIGKTISPLTSQCPSNQNMVSVYLEWNAQKQ
>LR027517|1406302:1429904|1407768_1408989_+|VCU53774.1|DBSCAN-SWA
MDLFPVLKELAQKTPSKILLIVLDGVGGLPLEPGGPTELEAAKTPNLDRLAEESALGLLTPVYPGLAPGSGPGHLALFGYDPFRYVVGRGALSALGLGADFREGDVALRGNFATLDPEGKVVDRRAGRPPTEENQRVIAKLKEAIPRIEDVEVHFYTESEHRFLVILRGEGLEDKVTDTDPQKTGLPPLKAKALDEASEKTARIVNLLSERIREVLKDEPRMNGALFRGASKKPSFPRMQEVYKLTPAAIASYPMYKGLASLVGMEVLPVEGEGDALEGKLKALKENWGRYDFFYFHVKKTDAMGEDGNFRGKVEKVELFDALLPEILALGPDVLAITGDHSTPALLKAHSWHPVPLLLKAPYLRADEARRFTEREAQRGSLGHLRGVELMPLLLAHAGKLLKYGA
>LR027517|1406302:1429904|1406302_1407736_-|VCU53773.1|tRNA|DBSCAN-SWA
MAKEKGLTPQSQDFSEWYLEVIQRAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLKKEAEHVEGFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEAMMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIVMTHGDDKGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALQAKGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKETLPLAALPEVLPGKLDAFHEELYQRALDFQRAHTHKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEAEEGLCVRCGKPSAYGKRVVFAKAY
>LR027517|1406302:1429904|1417966_1418530_+|VCU53791.1|DBSCAN-SWA
MAYQRVPVDPNAPLKSGKTYEIVAAHKGGDVSRVTRADLERALQAKYGPGVRVLDWGKRGNDLVIRLKVEATSSSAGTSDPWAVPPAYGGAGCGSTKCPQPMGYMGGGDIYPAFLPALALSAAAVIAVLYLVWRIVAELKEAVELVPAPARAAAVAGAGVGVGALGLAALGVVALALVGGRRRRAYA
>LR027517|1406302:1429904|1414317_1414494_+|VCU53782.1|DBSCAN-SWA
MIELAAPYFLLALALYALLGVYVRARYGQPGPALAAAMAFLAGLMAAVLVVLAVGGGR
>LR027517|1406302:1429904|1411868_1412843_-|VCU53778.1|DBSCAN-SWA
MRPDPLLKLLEDPAYLVQADRGELLEVVVQALFARLPGWKASRPSQTNAPDNGLDVEAISPQGKRYLIQCKNLSTPADANLVRLTHAAKDLHRTHKGILICPSGFTKPALENAEALGVLTWGPEELRLLYQAASSEAAMRKLGLWEAPKSPGFWDGLAIHFKNWLAQTRKETLYVGIAILIVLGFLFLLTQGSSPQKAKRPVSSPEAVVRGYDSAYRYALSTNDWAPLYEWAFADFLERKVLPFIRERQSRGCVLRTEELEPMRITAVEALLDMAEVYVSKKWQQTLVCQDRPPKEVLNKAFSTYYLIKPDADGRLKVWLSDWN
>LR027517|1406302:1429904|1428924_1429185_+|VCU53812.1|DBSCAN-SWA
MIPKLTLRDVIVPPPVPAPLPGASVSPPARRSFQHVSGAVVGGRVDYRDLNAFAWYVAGGYLTLNRGRKRIGRTFRGAEDGRRERR
>LR027517|1406302:1429904|1416803_1417145_+|VCU53788.1|DBSCAN-SWA
MRVDRVRLEAVADILQHRLQEALEQPGRRVRFVLRTSPSDGVQVFLTYRPDGRLVLAIRRPGGKEDPREIQALAQHMGLEIREGPMEMAGRVPRPRVGPRKYLVAFCEPGRTG
>LR027517|1406302:1429904|1413359_1413905_-|VCU53780.1|DBSCAN-SWA
MISALETGSSLPTKLQAERLFALLRALRWTPEEFAEATGLDVPLVYRPSGEPREDVVWVPVVGSGVAGRPWPESGSMPVPRPLVRPGSVLIQVEGDSMDTGEEDGLRDGDLVLVDQNLKELREGRVYAVEIIGDGITIKRARKLGNRWILISDNPKGPLLEPEEVRVIGEVYRKISIREVK
>LR027517|1406302:1429904|1426310_1426760_+|VCU53809.1|DBSCAN-SWA
MLNLLGVKPEDVQNLVRQGQAALDELRAEMACVKESLQAIERILGYEYGRPARGLMGHDPYRLPLIAQVDAGAQPTRVDLAGLLGKLATRGHVVNIGDAKVRIWFVSGAQRVGPYILLPSAAVELSFALEALEVADAGEGPSRVQLLMQ
>LR027517|1406302:1429904|1426116_1426332_+|VCU53808.1|DBSCAN-SWA
MGEKVEVVQNRVSLWQAYKQGVGVGLGILTVYALALLLLGFLASRALASAPSGGNEPPKNEGGKACSTSWV
>LR027517|1406302:1429904|1414133_1414325_+|VCU53781.1|DBSCAN-SWA
MQVYRVDEVARMFKVSRITVLRWIKNGRLRARKLGKGYRITEQDLDLFLNADTNGLVKGGSRD
>LR027517|1406302:1429904|1415082_1415361_+|VCU53785.1|DBSCAN-SWA
MRDVYRLVNAIEDLEHQAGIQHVRVRAKAEGKEILARLEAVGYEVRLFPEIGPRDAEVSWIAMAFYQGRLVAHAYGDTREEALRGLAGEVGA
>LR027517|1406302:1429904|1419036_1419405_+|VCU53793.1|DBSCAN-SWA
MIPFTGEEIAGGAAFLLMLGVRVQSEEEKAAFLRAWQGALFGLMPPAQVLDVLKVGEALAQYGIGKNRVPGMGSVENLPPWLRILLGGGVLAIAAYGGVRAVMDVRASRTAGGAPDGAPPSA
>LR027517|1406302:1429904|1422128_1422644_+|VCU53800.1|DBSCAN-SWA
MQEAFERIKRLRPGARPITILRSGPEFQAYGGRQKVKVGEFVVPSGATWVFPNPVPVVLKLYDSNGNQLPHTTDVFFARRTKGFDFPEFLVKAQYASYYDLSEAQQRDAKFYQNILQTASPLYAPTPPQGIVLREGDTLEIYVETDPGITVNLNDSRTRIELPVGVDNSNV
>LR027517|1406302:1429904|1422652_1423528_+|VCU53801.1|DBSCAN-SWA
MALLDSLRNAVRRGLGVFQDAPAAPSPTPQPQPQPARPAPAAVQASGWQFAWIDNEDFDATGLAYRPNEYFALAQMRTPDTAHFRILAGERRLRIYLKGLAAFAGQNLATAQARTVTLPYLIPSLQGAPTLPSTYHPDVAVWAKVGGVWQRCQINAVNYAGQQVTFVEPAGVTGTQDIEVYYTHADGQFRLRVARDAGGVDDSVATVFNQSFSTMHSVDQNNLETMLAWPQQVELVPGTRLLLEIFTTQVPMVWNERAGHYIQIAAMGRRVEVLDKGRLLRLAELENRGGL
>LR027517|1406302:1429904|1424504_1424810_+|VCU53804.1|DBSCAN-SWA
MNDLVAKGSSADTNCWSYAKREACFWEICSPALWGNYNACMDYVKGQGPRPGNLFNYDDSRAVDQAAQQYAALKGELETYQAQIEGVKKQLQQLATEGVVC
>LR027517|1406302:1429904|1425576_1426005_+|VCU53807.1|DBSCAN-SWA
MSVQDFLPQGQVWLVWLVQALLAAGLIALLSGLIVRVVSPIPVVGPVLAAAVRMLFSNYEKWLSERVPKLAEQAVLATEEKWRKVGSQYDPAARAQAKLQEAIEALQQMAPGLPRDIAQKQIEAALARIRAMGMEQKVGGGK
>LR027517|1406302:1429904|1423908_1424163_+|VCU53803.1|DBSCAN-SWA
MDVFGGLIGGVTNLLDDFIFTDEERMALEAQKAAAQAQLEAARLAQERAMLEAAARARQAQALTVAAVTVGAALVMAVLVWRWT

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VCU53773.1|1406302_1407736_-|tRNA	Proline--tRNA ligase	A0A2K9L3R9	Tupanvirus	6.8e-93	45.5
VCU53774.1|1407768_1408989_+	hypothetical protein	NA	NA	NA	NA
VCU53775.1|1408998_1409547_+	hypothetical protein	NA	NA	NA	NA
VCU53776.1|1409524_1410499_-	Bifunctional oligoribonuclease and PAP phosphatase NrnA	NA	NA	NA	NA
VCU53777.1|1410669_1411842_-	Transposase from transposon Tn916	Q859R3	Thermus_virus	1.8e-155	79.1
VCU53778.1|1411868_1412843_-	hypothetical protein	Q859R2	Thermus_virus	6.3e-167	95.6
VCU53779.1|1412893_1413358_-	hypothetical protein	Q859R1	Thermus_virus	7.1e-84	99.4
VCU53780.1|1413359_1413905_-	LexA repressor	Q859R0	Thermus_virus	3.9e-89	92.2
VCU53781.1|1414133_1414325_+	hypothetical protein	C8CHN0	Thermus_virus	6.6e-12	61.1
VCU53782.1|1414317_1414494_+	hypothetical protein	B3XVT1	Thermus_virus	2.6e-15	86.2
VCU53783.1|1414490_1414649_+	hypothetical protein	NA	NA	NA	NA
VCU53784.1|1414651_1414939_+	hypothetical protein	C8CHN3	Thermus_virus	3.7e-14	50.0
VCU53785.1|1415082_1415361_+	hypothetical protein	C8CHJ9	Thermus_virus	1.3e-11	48.6
VCU53786.1|1415357_1415567_+	hypothetical protein	NA	NA	NA	NA
VCU53787.1|1415563_1416814_+	hypothetical protein	Q859U0	Thermus_virus	1.6e-167	78.9
VCU53788.1|1416803_1417145_+	hypothetical protein	Q859T8	Thermus_virus	3.3e-46	81.6
VCU53789.1|1417146_1417554_+	hypothetical protein	Q859T7	Thermus_virus	8.7e-70	99.2
VCU53790.1|1417570_1417864_+	hypothetical protein	Q859T6	Thermus_virus	2.2e-46	99.0
VCU53791.1|1417966_1418530_+	hypothetical protein	Q859T5	Thermus_virus	2.9e-71	92.0
VCU53792.1|1418576_1418972_+	hypothetical protein	Q859T4	Thermus_virus	8.0e-20	73.9
VCU53793.1|1419036_1419405_+	hypothetical protein	Q859T3	Thermus_virus	7.4e-52	89.9
VCU53794.1|1419346_1419916_+	N-acetylmuramoyl-L-alanine amidase AmiC	C8CHK8	Thermus_virus	3.3e-75	81.7
VCU53795.1|1419912_1420107_+	hypothetical protein	Q859T1	Thermus_virus	3.0e-20	75.0
VCU53796.1|1420103_1420691_+	hypothetical protein	C8CHK9	Thermus_virus	1.2e-51	59.6
VCU53797.1|1420687_1420885_+	hypothetical protein	B3XVS9	Thermus_virus	1.6e-13	97.3
VCU53798.1|1420885_1421566_+	hypothetical protein	Q859T0	Thermus_virus	3.9e-123	95.6
VCU53799.1|1421700_1422117_+	hypothetical protein	Q859S9	Thermus_virus	1.4e-67	94.2
VCU53800.1|1422128_1422644_+	hypothetical protein	Q859S8	Thermus_virus	3.0e-91	95.9
VCU53801.1|1422652_1423528_+	hypothetical protein	Q859S7	Thermus_virus	1.9e-146	94.5
VCU53802.1|1423540_1423906_+	hypothetical protein	Q859S6	Thermus_virus	6.1e-22	71.8
VCU53803.1|1423908_1424163_+	hypothetical protein	Q859S5	Thermus_virus	2.2e-10	97.1
VCU53804.1|1424504_1424810_+	hypothetical protein	Q859S4	Thermus_virus	7.5e-50	94.1
VCU53805.1|1424809_1425046_+	hypothetical protein	Q859S3	Thermus_virus	6.5e-25	100.0
VCU53806.1|1425035_1425338_+	hypothetical protein	Q859S2	Thermus_virus	2.5e-37	92.0
VCU53807.1|1425576_1426005_+	hypothetical protein	C8CHM2	Thermus_virus	2.1e-37	62.0
VCU53808.1|1426116_1426332_+	hypothetical protein	C8CHM4	Thermus_virus	4.2e-07	51.7
VCU53809.1|1426310_1426760_+	hypothetical protein	C8CHM5	Thermus_virus	2.6e-46	62.0
VCU53810.1|1426756_1427833_+	hypothetical protein	C8CHM6	Thermus_virus	9.4e-79	63.8
VCU53811.1|1427842_1428928_+	hypothetical protein	C8CHM7	Thermus_virus	1.2e-84	49.1
VCU53812.1|1428924_1429185_+	hypothetical protein	Q859R6	Thermus_virus	5.9e-11	50.6
VCU53813.1|1429355_1429904_+	hypothetical protein	Q859R5	Thermus_virus	3.9e-89	87.8

3. LR027520

CRISPR-Cas detection and classification

Crispr_ID: LR027520_1

• CRISPR_ID: LR027520_1
• CRISPR_location: 73912-74127
• CRISPR_type: TypeI-E
• Repeat_type: I-E,II-B
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of LR027520_1

Consensus_repeat	Method
CGGTCCATCCCCACACGCGTGGGGA--CTACG	PILER-CR
CGGTCCATCCCCACACGCGTGGGGACTACGC	CRT
GGTCCATCCCCACACGCGTGGGGACTAC	CRISPRCasFinder

spacers of LR027520_1

>1.1|73942|32|LR027520|PILER-CR
CCGATGTCGGCCAGGGTGAGATAGAGGGTGTC
>1.2|74004|32|LR027520|PILER-CR
CTCCCGTTCCCTCTCACTCATCTGCCAGATCT
>1.3|74066|31|LR027520|PILER-CR
GGACCTGTCTGACGCTTTCTCCGCTGAGACT
>1.4|73943|31|LR027520|CRT
CGATGTCGGCCAGGGTGAGATAGAGGGTGTC
>1.5|74005|31|LR027520|CRT
TCCCGTTCCCTCTCACTCATCTGCCAGATCT
>1.6|74067|30|LR027520|CRT
GACCTGTCTGACGCTTTCTCCGCTGAGACT
>1.7|73941|34|LR027520|CRISPRCasFinder
GCCGATGTCGGCCAGGGTGAGATAGAGGGTGTCC
>1.8|74003|34|LR027520|CRISPRCasFinder
GCTCCCGTTCCCTCTCACTCATCTGCCAGATCTT
>1.9|74065|33|LR027520|CRISPRCasFinder
GGGACCTGTCTGACGCTTTCTCCGCTGAGACTC

CRISPR arrays and Neighbor proteins around LR027520_1

CRISPR arrays

The CRISPR arrays of LR027520_1

>merge|LR027520|1|73912-74127|PILER-CR,CRT,CRISPRCasFinder
CGGCCCATCCCCACACGCGTGGGGACTACGCCGATGTCGGCCAGGGTGAGATAGAGGGTGTCCGGTCCATCCCCACACGCGTGGGGACTACGCTCCCGTTCCCTCTCACTCATCTGCCAGATCTTGGTCCATCCCCACACGCGTGGGGACTACGGGACCTGTCTGACGCTTTCTCCGCTGAGACTCGGTCCATCCCCACACGCGTGGGGACTACAC

>LR027520|1|1|73912-74126|PILER-CR
CGGCCCATCCCCACACGCGTGGGGACTACG	CCGATGTCGGCCAGGGTGAGATAGAGGGTGTC
CGGTCCATCCCCACACGCGTGGGGACTACG	CTCCCGTTCCCTCTCACTCATCTGCCAGATCT
TGGTCCATCCCCACACGCGTGGGGACTACG	GGACCTGTCTGACGCTTTCTCCGCTGAGACT
CGGTCCATCCCCACACGCGTGGGGACTACA

>LR027520|1|1|73912-74127|CRT
CGGCCCATCCCCACACGCGTGGGGACTACGC	CGATGTCGGCCAGGGTGAGATAGAGGGTGTC
CGGTCCATCCCCACACGCGTGGGGACTACGC	TCCCGTTCCCTCTCACTCATCTGCCAGATCT
TGGTCCATCCCCACACGCGTGGGGACTACGG	GACCTGTCTGACGCTTTCTCCGCTGAGACT
CGGTCCATCCCCACACGCGTGGGGACTACAC

>LR027520|1|1|73913-74125|CRISPRCasFinder
GGCCCATCCCCACACGCGTGGGGACTAC	GCCGATGTCGGCCAGGGTGAGATAGAGGGTGTCC
GGTCCATCCCCACACGCGTGGGGACTAC	GCTCCCGTTCCCTCTCACTCATCTGCCAGATCTT
GGTCCATCCCCACACGCGTGGGGACTAC	GGGACCTGTCTGACGCTTTCTCCGCTGAGACTC
GGTCCATCCCCACACGCGTGGGGACTAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
LR027520.1|VCU54670.1|68383_69193_+|Kynurenine-formamidase	unknown	unknown	gnl|CDD|224790
LR027520.1|VCU54672.1|69745_70702_+|Solute-binding-protein-Dde_0634	unknown	unknown	gnl|CDD|270320
LR027520.1|VCU54675.1|72457_73144_+|N-acyl-homoserine-lactonase	unknown	unknown	gnl|CDD|293815
LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3	cas6e	cd09664_cas6e_CAS-I-E	gnl|CDD|187795
LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1	cas8e	cd09669_cas8e_CAS-I-E	gnl|CDD|274192
LR027520.1|VCU54680.1|76125_76335_-|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
LR027520.1|VCU54681.1|76376_77210_+|hypothetical-protein	unknown	unknown	gnl|CDD|372648
LR027520.1|VCU54667.1|66628_66916_+|hypothetical-protein	unknown	unknown	gnl|CDD|366690
LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl|CDD|237559
LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
LR027520.1|VCU54671.1|69442_69718_+|hypothetical-protein	unknown	unknown	gnl|CDD|270367
LR027520.1|VCU54677.1|74185_74563_-|CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
LR027520.1|VCU54668.1|66912_67752_+|hypothetical-protein	unknown	unknown	gnl|CDD|222853
LR027520.1|VCU54676.1|73155_73908_+|hypothetical-protein	unknown	unknown	gnl|CDD|377121
LR027520.1|VCU54673.1|70701_71157_+|hypothetical-protein	unknown	unknown	gnl|CDD|377284
LR027520.1|VCU54669.1|67891_68287_+|Sulfurtransferase-FdhD	unknown	unknown	gnl|CDD|376873
LR027520.1|VCU54674.1|71153_72455_+|C4-dicarboxylate-TRAP-transporter-large-permease-protein-DctM	unknown	unknown	gnl|CDD|129868

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD	cas5	cd09756_cas5_CAS-I-E	4.1e-52	171.3	0.5
LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1	cas8e	cd09669_cas8e_CAS-I-E	5e-126	416.1	0.9
LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3	cas6e	cd09664_cas6e_CAS-I-E	5.4e-68	223.8	0.0
LR027520.1|VCU54677.1|74185_74563_-|CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.7e-32	106.2	0.1
LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	1.6e-59	196.5	0.0
LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC	cas7	pfam09344_cas7_CAS-I-E	1.1e-123	408.1	0.0
LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	1.2e-109	360.2	0.0
LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2	cse2gr11	cd09670_cse2gr11_CAS-I-E	2.8e-42	139.4	9.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
LR027520.1|VCU54670.1|68383_69193_+|Kynurenine-formamidase	gnl|CDD|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	8.37402e-66
LR027520.1|VCU54672.1|69745_70702_+|Solute-binding-protein-Dde_0634	gnl|CDD|270320	cd13602, PBP2_TRAP_BpDctp6_7, Substrate-binding domain of a pyroglutamic acid binding DctP subfamily of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold. DctP6 and DctP7 groups of the TRAP transporters that involved in pyroglutamic acid transport. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.0649e-136
LR027520.1|VCU54675.1|72457_73144_+|N-acyl-homoserine-lactonase	gnl|CDD|293815	cd07729, AHL_lactonase_MBL-fold, quorum-quenching N-acyl-homoserine lactonase, MBL-fold metallo-hydrolase domain. Acyl Homoserine Lactones (also known as AHLs) are signal molecules which coordinate gene expression in quorum sensing, in many Gram-negative bacteria. Quorum-quenching N-acyl-homoserine lactonase (also known as AHL lactonase, N-acyl-L-homoserine lactone hydrolase, EC 3.1.1.81) catalyzes the hydrolysis and opening of the homoserine lactone rings of AHLs, a reaction that can block quorum sensing. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.9896e-31
LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	8.20162e-159
LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3	gnl|CDD|187795	cd09664, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	5.04096e-72
LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1	gnl|CDD|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	6.56215e-134
LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	4.30529e-105
LR027520.1|VCU54681.1|76376_77210_+|hypothetical-protein	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.14427e-11
LR027520.1|VCU54667.1|66628_66916_+|hypothetical-protein	gnl|CDD|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.17426e-09
LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2	gnl|CDD|237559	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional.	1.00374e-68
LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	6.23903e-145
LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.5215e-53
LR027520.1|VCU54671.1|69442_69718_+|hypothetical-protein	gnl|CDD|270367	cd13649, PBP2_Cae31940, Substrate binding domain of an uncharacterized protein similar to ABC-type transporter for thiamin biosynthetic pathway intermediates; a member of the type 2 periplasmic binding fold superfamily. This subfamily includes the periplamic-binding protein Cae31940 which is phylogenetically similar to the ThiY/THI5 family. ThiY is the periplasmic N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP) binding component of the ABC transport system (ThiXYZ). FAMP is imported into cell by the transporter, where it is then incorporated into the thiamin biosynthetic pathway. The closest structural homologs of ThiY are THI5, which is responsible for the synthesis of 4-amino-5-(hydroxymethyl)-2-methylpyrimidine phosphate (HMP-P) in the thiamin biosynthetic pathway of eukaryotes, and periplasmic binding proteins involved in alkanesulfonate/nitrate and bicarbonate transport. After binding the ligand, They interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ThiY/THI5 proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.3803e-37
LR027520.1|VCU54677.1|74185_74563_-|CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	2.92884e-38
LR027520.1|VCU54668.1|66912_67752_+|hypothetical-protein	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.87708e-47
LR027520.1|VCU54676.1|73155_73908_+|hypothetical-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	1.63855e-139
LR027520.1|VCU54673.1|70701_71157_+|hypothetical-protein	gnl|CDD|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.23858e-12
LR027520.1|VCU54669.1|67891_68287_+|Sulfurtransferase-FdhD	gnl|CDD|376873	pfam02634, FdhD-NarQ, FdhD/NarQ family. A pan-bacterial lineage of proteins. Nitrate assimilation protein, NarQ, and FdhD are required for formate dehydrogenase activity. Structurally, they possess a deaminase fold with a characteristic binding pocket, suggesting that they might bind a nucleotide or related molecule allosterically to regulate the formate dehydrogenase catalytic subunit.	5.00937e-64
LR027520.1|VCU54674.1|71153_72455_+|C4-dicarboxylate-TRAP-transporter-large-permease-protein-DctM	gnl|CDD|129868	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit. The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	7.26229e-94

Protein sequences

>LR027520.1|VCU54676.1|73155_73908_+|hypothetical-protein
MTVDLNADAGESYGAFAYGHDREIFPLVTSANLACGFHGGSPGRILEAVRLAKAHGVAVGAHPGFPDLVGFGRREMALSPEEVYADVLYQIGALSAFLKAEGLPLHHVKPHGALYLKACRDRETARAIALAVKAFDPGLPLVVLPGTVYEEEARKAGLRVVLEAFPERAYLRNGQLAPRSMPGSWITDPEEAARRALRMVLEGRVEALDGGEVAVQAETLCIHGDNPNAPEVARAVREALEQAGVEVRAF
>LR027520.1|VCU54675.1|72457_73144_+|N-acyl-homoserine-lactonase
MKVIPVHTGFPGRSHRGYLGLSGAYLVVGSRLLLYDTLGFGEREGLYARLEVLGVSPLDVTGVVLSHLHFDHAANADLFPWAEVYVHEAELRHAERVAKDPRLDPACLAHLPKALPRLTAVPEGPLEEGLSLLHLPGHTPGLLGLAVEGVGVLVSDAVKSRFDLEGPPAPPCLDPERALKSRERLYRFPRLFPGHDVPLRREGDRFLPEGEACLEVALPHGARVTLKL
>LR027520.1|VCU54674.1|71153_72455_+|C4-dicarboxylate-TRAP-transporter-large-permease-protein-DctM
MSLLAAGLVLVALLFLLLALGVYVGLALLLVGTAGLALFTTAPPGPNVATALWTSTSSWSLAALPLFVWMGEILYRSRLAQELFQGLAPLLGRLPGGLLHVNVVASALFAAVIGSSAATTATVGRFTLPELLRQGYPKALALGSLAGAGTLGFLIPPSIVMIVYGVMAEVSVARLFMAGVVPGLLLTLLFMLTVALLAHRHRKALPRGPSPASREALKGLLSVLPVLFLILLVLGSIYLGVATPTEAAAIGVAGAFLLTVLRREFGLELFRESLLGAVRTTSMIGLILAGAGVLTLAMGFTGIPRALATWAVEAGITPIALVLFLSLVYILLGWFLDGISIVVLTISVILPVVKAIGLDPLWFGVYLVLMVELAQITPPVGFNLFVLQSLSGEDLFRIARYSLPFMGVLLLMVALLVAFPGLATWLPRTMTGG
>LR027520.1|VCU54673.1|70701_71157_+|hypothetical-protein
MLKGLYRLSELLALLLGLFVLLVILAQVVGRFLGFVVPSALELAGFATAGLIFLGLGPTFRAGGHIRVELLLRRLPPKARAPLGRAALGLGAAASLYAAFHLWAKTLESLRFGDLAPGLLPLPLWIPLAVVAFGMSVFAVALLEALLREAP
>LR027520.1|VCU54672.1|69745_70702_+|Solute-binding-protein-Dde_0634
MKRLVTALSLLALGALAQTWNMATPYPPGNFHTQNILQFVKEVEEATGGRVRITVHPGGSLFPHPQILPAVRNGQVQMGEVLMSLLANENPLFNLDSIPFVVSGYEDAWRLYQAQRPEVEKWLAQRGVVFLYAVPWPPQGLYTKKPVNSAQDLKGLRFRAYNPATARLAELLGMTPVQVEAADIPQAFATGIVEAMITSPTTGVDSQAWDFARYFYDVKAWIPKNMVVIGRRAFESLSPQDREALLQAAKRAEERGWKMSQEEEAKALKTLAQRGMQVVKPSPQLMADLKKAGETMILEWQRQAGATGVRVYRQYLGR
>LR027520.1|VCU54671.1|69442_69718_+|hypothetical-protein
MGFYDRTIQMQAQGRDIVAFVEVGRYPALVLGVRADLADQVKTVADLKGKKVGVTAPGSSTRFFLNCLLVKNGLKRTYTNELVDRILQNLR
>LR027520.1|VCU54670.1|68383_69193_+|Kynurenine-formamidase
MCAPLVMEQVARSLSRRSFLASGLAALAGAALAQAQVPGKAFAKAVDLTHELTPEIPLFPGAEPMRITTLVTVRQNGYYGNRLDLWEHSGTHMDAPAHFVEGAPTAEKLPVGVLIAPLAVIHIHEKAAKDPDAQVTPDDLLAYERRYGRLPKGAFVAMHSGWEARWKDPKAFLNQDASGTLHFPGFSPEAAEFLVQEREIVGIGVDTLSLDFGPSKDFKTHVTVLGAGKYGLENLANLAQVPPSGALIFVGGPKHQKASGGPVRAVAVW
>LR027520.1|VCU54669.1|67891_68287_+|Sulfurtransferase-FdhD
MCALLDQAQRLFRATGGLHAAALFDREGRLVALREDVGRHNALDKLIGWAFLQGKLPLHDHILLVSGRAGYELLVKAVAAGIPVFCAVSAPTSLAVALAQAYGLTLVGFLRPGRMNVYAGRERVGPPRGPT
>LR027520.1|VCU54668.1|66912_67752_+|hypothetical-protein
MKALKGAYPLRLLSRVLGVPRSTLYYRPQDPPPEEAALRGRLRALAEAWPRYGYRRLTALLRGEGFQVGEKRVRSLMREEGLLLPRKGPSPRTTSPGGLLPEGVKNLLPGLEVTCPHQVWVADLSYVVLGEGVAYLAVVMDLHTRKILGVALGPRLSQGLALAALEMALREGCPEVHHSDRGVQYTSRAYVERLLGLGVRLSYAGTGRPWENGHAERLIRMIKEEWVALREYRTLAEARASVKAFVLEVYNRKRPHSALGYLTPEAFSESLLKGGGSPD
>LR027520.1|VCU54667.1|66628_66916_+|hypothetical-protein
MRRWSAKEKAKIVLEVLSGQRTVAEACRAYGVAESLLYRWQREFLENAHAAFTSGCAEQEARIRELERLVGQMALELEVLKKASGLYRQRKGGSW
>LR027520.1|VCU54677.1|74185_74563_-|CRISPR-associated-endoribonuclease-Cas2
MVVMILEKVPRSLRGDLTRFLVEVDTGVFVGRVSATVRELLWERAVEKAEGGRVALAYRTNNEQGFALRLHGYPDRFLRDFDGIVLVSVRNAEAARKAEKLSRQVERYKKRLAKGSEGDLESQSP
>LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1
MPPVPSARNLKELPKFRDGLSYLYVEHAVVEREAGGIGIYDQEGLTLAPVAGLGVLFLGPGTRITHAAVRLLAENGCTVAWVGEGMARFYAQGLGDTRSAARFYRQARAWADPALHLEVVMRLYRMRFSEPLPEGLTLEQVRGLEGVRVRNAYARWSRETGVPWYGRSYDRGNWRAADPVNRALSAGASYLYGLAHAAIVSLGFSPALGFIHTGKLLSFVYDIADLYKADYLVPAAFRTVAESEEAVERRVRRALREAIQEGRLLERMAEDLLNLFRGLGLPEEEDPVEEDPTRPGGLWDLEGEVEGGVAYGGDDPGEGAEEPEG
>LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3
MWLSKLVLNPASRAARRDLANPYEMHRTLSRAVSEALKEGRERLLWRLEPTRGLEPPVVLVQTLTEPDWSVLDEGYAQVFPPKPFHPALKPGQRLRFRLRANPAKRLAATGKRVALKTPAEKVAWLERRLEEGGFRLLEGERGPWVQILQDTFLEVRRKKDGEEAGKLLQVQAVLFEGRLEVVDPERALATLKRGVGPGKALGLGLLSVAP
>LR027520.1|VCU54680.1|76125_76335_-|hypothetical-protein
MGYSYLLGGKPSEDLLLVLEAEEGRLVYDQPAGPFSERRFAARYVREEVLSREAVPGGPPAWEVDRVAQ
>LR027520.1|VCU54681.1|76376_77210_+|hypothetical-protein
MLSRLIAAFCIIDDALQAMGYKDDPQAKTPASAILTLALLAALEFGGKHNKALALAKDLGLFTHVPSPSRFNRRLHALYPLLLPLLHLLAQVWKHLHQAQAYALDTFPLPACENIRAPRSRLFPDKAYRGFIPSKRVYFHGLKLHLLVDDGKFVHEVNLTPGSFHDLASLLLLPLDLPEGAELYLDRGYESHLYEDLLREAQEVVPMVIRRRNSRRYLPWMQYLAIVGRRVVETVGSMLHHLFPRRIHAVTQEGFVIKVLTFVLAHNISLLTQKMAG
>LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD
MPTLLLRLQGPMQSWGTRSRFDHRDTWPYPTKSGVVGLLAAALGRDREQDVSDLAALRMGVRVDYQTAQSVLTADLKGKGNVQSWRYYLADAAFLVGLEGERALLETLHGALRNPRFPLYLGRKSYVPSPPPYLPDGLVEAPLAEALEGYS
>LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC
MKLLEVHILQTVAPSNLNRDDTGSPKDALFGGFRRARISSQAQKRAVRVAFRDWPLLSEEERAVRTKRLVEELLRRLAGVEEELARRAIENALNALGFGVKEGRTEYLLFLGNRELDALAQGIRENLEALSGEVKGKKKAEVPSELKKALERVLDGGKAVDLALFGRMLADRPELGVDAAAQVAHALSTHKVDREFDFYTAVDDLNPKEDTGAGMMGDVEFYSATLYRYAVVDLDKLVENLQGDKELALKGVLAFLEAFALTLPSGKQNSFAAHNPPLFVAFRAGEGMPRNLATAFEKPLRPREDKALSALSVERLVQEWARFDKVYGPLNPEWKGALDLTEAEVEGLPKLESFPELRKKVEEALQALLEV
>LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2
MSQGERFLDWLRRLQGQKAWTAARAALRRSLAFPPGAYPRAMPYVEPFLAKGDWRREEREAHYLVAALYALKDGDHQVGRTLAQALALRKNATGSASVEKRFLALLEADRDQIAFRLRQAVALVEGGIDFARLLDDLLRWFSPERHVQARWAREFYGAEASEEEKKEVEA
>LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1
MAKFNLIDEPWIPVLKGGRVVEVGIGEALLRAHEFARIETPSPLEEAALHRLLLAVLHRALRGPRRLEDVLDWWWEGGFPQDPIRDYLNRFQDRFFLFHPEAPFLQVADLPEENPLPWSKLLPELASGNNPTLFDHTTEENLPKATYAQAARALLVHQAFAPGGLLRRYGVGSAKDAPVARPALFLPTGRNLLETLLLNLVPYNPGEDAPIWEIPPLRFGDLEGGKTAWPLSGRTRVYTWPARGVRLLDERDGVRFMGYGPGVEPLESPHRDPMVAQRLDAKGNLLVLRLSEERSFWRDFSAMLPRQGGKVAATLDHAHNLQGELEDEGLEGRITLRVLGQVSDQAKVLDIRREVYPLPSGLLTPKAEENLEKALKMAEELGQGLKHLAQEVAKAVVGERDRGHGRSPYLEELTKLANSLPLERLYWHTLDGAFPRFFARVEEEASLDLWREALRGAALEAWKATRRFLGTGARHLKALAQGEQEFGRLLGELGEEVRT
>LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3
MSVEEAALALWAKSGDPFHPLLAHMLDTAAVALAVLRREPPRTRALYAEDWGLPEEGALAWAAALVGLHDLGKASPAFQAGWEEGKERVQRAGLPFGELLDWVAHGVFTELFLRRLLKEKGLPERAANDLAAALGAHHGFPANAEEKSRARRHLKAEDPLWKEARRWLLEEVFRRLGAPLPPSQGNGEARSEVVLRVMALASFADWVASDPSLFPYGRDPRRGNYLKEALRLAQEALNRLGWPAFAKAQRREFGELFPYIPKPNALQEKVPALLEGACTPVLLLVEAPMGMGKTEAALYAHHLLQAGLGHRGLYVALPTQATANGLFPRVRGFLERLGEGSRLELQLQHGTALLNPHYAELLERAAPRQVGEEEEGGAVASAWFSARKRAMLAPYGVGTLDQALLGVLRVKHHFVRLWGLMNRVVVLDEVHAYDVYTSGLLQALLRWLRALGSSAVVMTATLPPSRRRALLEAWAGKEVEGQDLGPYPRVVLVGEGVKARSLPPAREVEVALEVLREVDVEPLAQRLKGALPGAVGAIVNTVDRAQALYRAFGEGRRLTLGELAPGLGKAQEGEAWQEVLEARKDAVVGKVLPDGTLVFLLHARFPAEERALRESVVLALFGKEGPRPPRAILVATQVAEQSLDLDVDLLYTDLAPIDLLFQRSGRLHRHERPRPEEHARPRLLLGVPEDLDFGKPLYWDKVYEDYVLLATWRALSGRDRLRVPGHLEALLEEVYEGEDPGRFPEDLRERAKKSLKALQERRDREANTARRLSLSELGRLLAYWDEGALVAQERLEDDEEKAETQRLLTRLGDPSVAVVPLFRAGEGLFLDREGRRRAPLRGEVSREEAEALFRRAVRLSRFPLPQELLKEEPPPAWRKSGLLRGLRPLEVGRVFGSGERAFRVELDAELGVVYLPV

Crispr_ID: LR027520_2

• CRISPR_ID: LR027520_2
• CRISPR_location: 84786-85060
• CRISPR_type: TypeI-E
• Repeat_type: I-E,II-B
• Spacer_info: 4 spacers
• Cas_protein_info: WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,TnpB_regular.1

Consensus repeat of LR027520_2

Consensus_repeat	Method
GTAGTCCCCACATGCGTGGGGATGGACCG	PILER-CR
GTAGTCCCCACATGCGTGGGGATGGACCG	CRISPRCasFinder
GTAGTCCCCACATGCGTGGGGATGGACCG	CRT

spacers of LR027520_2

>2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT
ATGCTATCCAAAATGCCGTCAAGCTTAGCTTC
>2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT
CTCGGCCTCGTGGACGACGTGAACCGTGCCAAC
>2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT
GCCGCCCTGTGGTTCCGCTACGGCTCCGGGCGG
>2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT
TAGAGCTCCTCCAGGGTCTTGGGGCGGTCCCT

CRISPR arrays and Neighbor proteins around LR027520_2

CRISPR arrays

The CRISPR arrays of LR027520_2

>merge|LR027520|2|84786-85060|PILER-CR,CRISPRCasFinder,CRT
GTAGTCCCCACATGCGTGGGGATGGACCGATGCTATCCAAAATGCCGTCAAGCTTAGCTTCGTAGTCCCCACATGCGTGGGGATGGACCGCTCGGCCTCGTGGACGACGTGAACCGTGCCAACGTAGTCCCCACATGCGTGGGGATGGACCGGCCGCCCTGTGGTTCCGCTACGGCTCCGGGCGGGTAGTCCCCACATGCGTGGGGATGGACCGTAGAGCTCCTCCAGGGTCTTGGGGCGGTCCCTGTAGTCCCCACATGCGTGGGGATGGACCT

>LR027520|2|2|84786-85060|PILER-CR
GTAGTCCCCACATGCGTGGGGATGGACCG	ATGCTATCCAAAATGCCGTCAAGCTTAGCTTC
GTAGTCCCCACATGCGTGGGGATGGACCG	CTCGGCCTCGTGGACGACGTGAACCGTGCCAAC
GTAGTCCCCACATGCGTGGGGATGGACCG	GCCGCCCTGTGGTTCCGCTACGGCTCCGGGCGG
GTAGTCCCCACATGCGTGGGGATGGACCG	TAGAGCTCCTCCAGGGTCTTGGGGCGGTCCCT
GTAGTCCCCACATGCGTGGGGATGGACCT

>LR027520|2|2|84786-85060|CRISPRCasFinder
GTAGTCCCCACATGCGTGGGGATGGACCG	ATGCTATCCAAAATGCCGTCAAGCTTAGCTTC
GTAGTCCCCACATGCGTGGGGATGGACCG	CTCGGCCTCGTGGACGACGTGAACCGTGCCAAC
GTAGTCCCCACATGCGTGGGGATGGACCG	GCCGCCCTGTGGTTCCGCTACGGCTCCGGGCGG
GTAGTCCCCACATGCGTGGGGATGGACCG	TAGAGCTCCTCCAGGGTCTTGGGGCGGTCCCT
GTAGTCCCCACATGCGTGGGGATGGACCT

>LR027520|2|2|84786-85060|CRT
GTAGTCCCCACATGCGTGGGGATGGACCG	ATGCTATCCAAAATGCCGTCAAGCTTAGCTTC
GTAGTCCCCACATGCGTGGGGATGGACCG	CTCGGCCTCGTGGACGACGTGAACCGTGCCAAC
GTAGTCCCCACATGCGTGGGGATGGACCG	GCCGCCCTGTGGTTCCGCTACGGCTCCGGGCGG
GTAGTCCCCACATGCGTGGGGATGGACCG	TAGAGCTCCTCCAGGGTCTTGGGGCGGTCCCT
GTAGTCCCCACATGCGTGGGGATGGACCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1	cas8e	cd09669_cas8e_CAS-I-E	gnl|CDD|274192
LR027520.1|VCU54694.1|91271_92252_+|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl|CDD|224525
LR027520.1|VCU54691.1|87485_89072_-|hypothetical-protein	TnpB_regular.1	-	gnl|CDD|273793
LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3	cas6e	cd09664_cas6e_CAS-I-E	gnl|CDD|187795
LR027520.1|VCU54687.1|83605_84595_-|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
LR027520.1|VCU54692.1|89174_90005_+|hypothetical-protein	unknown	unknown	gnl|CDD|238742
LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
LR027520.1|VCU54681.1|76376_77210_+|hypothetical-protein	unknown	unknown	gnl|CDD|372648
LR027520.1|VCU54695.1|92319_93552_+|Maltose-binding-periplasmic-protein	unknown	unknown	gnl|CDD|270451
LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl|CDD|237559
LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
LR027520.1|VCU54689.1|86250_87126_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54696.1|93599_94706_+|Lactose-transport-system-permease-protein-LacF	unknown	unknown	gnl|CDD|224096
LR027520.1|VCU54693.1|90038_91157_-|hypothetical-protein	unknown	unknown	gnl|CDD|376573
LR027520.1|VCU54697.1|94702_96067_+|L-arabinose-transport-system-permease-protein-AraQ	unknown	unknown	gnl|CDD|223472
LR027520.1|VCU54690.1|87118_87493_+|hypothetical-protein	unknown	unknown	gnl|CDD|238742
LR027520.1|VCU54688.1|85309_86254_+|hypothetical-protein	unknown	unknown	gnl|CDD|334588
LR027520.1|VCU54680.1|76125_76335_-|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD	cas5	cd09756_cas5_CAS-I-E	4.1e-52	171.3	0.5
LR027520.1|VCU54691.1|87485_89072_-|hypothetical-protein	TnpB_regular.1	-	9.1e-11	35.7	0.0
LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1	cas8e	cd09669_cas8e_CAS-I-E	5e-126	416.1	0.9
LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3	cas6e	cd09664_cas6e_CAS-I-E	5.4e-68	223.8	0.0
LR027520.1|VCU54687.1|83605_84595_-|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	8.8e-40	131.3	1.1
LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	1.6e-59	196.5	0.0
LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC	cas7	pfam09344_cas7_CAS-I-E	1.1e-123	408.1	0.0
LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	1.2e-109	360.2	0.0
LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2	cse2gr11	cd09670_cse2gr11_CAS-I-E	2.8e-42	139.4	9.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3	gnl|CDD|187795	cd09664, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	5.04096e-72
LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1	gnl|CDD|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	6.56215e-134
LR027520.1|VCU54695.1|92319_93552_+|Maltose-binding-periplasmic-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.55562e-83
LR027520.1|VCU54694.1|91271_92252_+|HTH-type-transcriptional-repressor-PurR	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.15221e-92
LR027520.1|VCU54681.1|76376_77210_+|hypothetical-protein	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.14427e-11
LR027520.1|VCU54687.1|83605_84595_-|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.70331e-34
LR027520.1|VCU54692.1|89174_90005_+|hypothetical-protein	gnl|CDD|238742	cd01465, vWA_subgroup, VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the VWA domain in these proteins. The members do have a conserved MIDAS motif. The biochemical function however is not known.	1.12659e-11
LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	4.30529e-105
LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	8.20162e-159
LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2	gnl|CDD|237559	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional.	1.00374e-68
LR027520.1|VCU54688.1|85309_86254_+|hypothetical-protein	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	1.20731e-07
LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.5215e-53
LR027520.1|VCU54691.1|87485_89072_-|hypothetical-protein	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	8.72572e-13
LR027520.1|VCU54696.1|93599_94706_+|Lactose-transport-system-permease-protein-LacF	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.47981e-28
LR027520.1|VCU54693.1|90038_91157_-|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.14123e-06
LR027520.1|VCU54697.1|94702_96067_+|L-arabinose-transport-system-permease-protein-AraQ	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	9.67165e-77
LR027520.1|VCU54690.1|87118_87493_+|hypothetical-protein	gnl|CDD|238742	cd01465, vWA_subgroup, VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the VWA domain in these proteins. The members do have a conserved MIDAS motif. The biochemical function however is not known.	3.19138e-14
LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	6.23903e-145

Protein sequences

>LR027520.1|VCU54687.1|83605_84595_-|hypothetical-protein
MGQEAKSARLLQMAEALKLRPMRVGELARRFGVSERTVERDLEALLDLGFPVERLARGLYRIADRSPSLHPIEALALFAAGRLLYHQAPTRQYRLALDKLARMLPEPLRGLLLRSTQGLEARQGESRTLEMVARALLERKVLAFEYRSGGSKNWRPKELLVYFLEANRANLGLYAIGYERTYHRAVLTFKLSRMRHARLLDETYEIPPDFDPNAYLRRAWGVVGVREEGVEVRLRFAPEAAWRVLEGDYPGLHLEEELPDGSLLARLEAAPFKGGVPWEVLAWVQSFGPRVEVLSPPELRRLWLEEAERVLALYGNRQEVSGSPPKVRA
>LR027520.1|VCU54686.1|80855_83609_-|CRISPR-associated-endonuclease/helicase-Cas3
MSVEEAALALWAKSGDPFHPLLAHMLDTAAVALAVLRREPPRTRALYAEDWGLPEEGALAWAAALVGLHDLGKASPAFQAGWEEGKERVQRAGLPFGELLDWVAHGVFTELFLRRLLKEKGLPERAANDLAAALGAHHGFPANAEEKSRARRHLKAEDPLWKEARRWLLEEVFRRLGAPLPPSQGNGEARSEVVLRVMALASFADWVASDPSLFPYGRDPRRGNYLKEALRLAQEALNRLGWPAFAKAQRREFGELFPYIPKPNALQEKVPALLEGACTPVLLLVEAPMGMGKTEAALYAHHLLQAGLGHRGLYVALPTQATANGLFPRVRGFLERLGEGSRLELQLQHGTALLNPHYAELLERAAPRQVGEEEEGGAVASAWFSARKRAMLAPYGVGTLDQALLGVLRVKHHFVRLWGLMNRVVVLDEVHAYDVYTSGLLQALLRWLRALGSSAVVMTATLPPSRRRALLEAWAGKEVEGQDLGPYPRVVLVGEGVKARSLPPAREVEVALEVLREVDVEPLAQRLKGALPGAVGAIVNTVDRAQALYRAFGEGRRLTLGELAPGLGKAQEGEAWQEVLEARKDAVVGKVLPDGTLVFLLHARFPAEERALRESVVLALFGKEGPRPPRAILVATQVAEQSLDLDVDLLYTDLAPIDLLFQRSGRLHRHERPRPEEHARPRLLLGVPEDLDFGKPLYWDKVYEDYVLLATWRALSGRDRLRVPGHLEALLEEVYEGEDPGRFPEDLRERAKKSLKALQERRDREANTARRLSLSELGRLLAYWDEGALVAQERLEDDEEKAETQRLLTRLGDPSVAVVPLFRAGEGLFLDREGRRRAPLRGEVSREEAEALFRRAVRLSRFPLPQELLKEEPPPAWRKSGLLRGLRPLEVGRVFGSGERAFRVELDAELGVVYLPV
>LR027520.1|VCU54685.1|79297_80797_-|CRISPR-associated-protein-CasA/Cse1
MAKFNLIDEPWIPVLKGGRVVEVGIGEALLRAHEFARIETPSPLEEAALHRLLLAVLHRALRGPRRLEDVLDWWWEGGFPQDPIRDYLNRFQDRFFLFHPEAPFLQVADLPEENPLPWSKLLPELASGNNPTLFDHTTEENLPKATYAQAARALLVHQAFAPGGLLRRYGVGSAKDAPVARPALFLPTGRNLLETLLLNLVPYNPGEDAPIWEIPPLRFGDLEGGKTAWPLSGRTRVYTWPARGVRLLDERDGVRFMGYGPGVEPLESPHRDPMVAQRLDAKGNLLVLRLSEERSFWRDFSAMLPRQGGKVAATLDHAHNLQGELEDEGLEGRITLRVLGQVSDQAKVLDIRREVYPLPSGLLTPKAEENLEKALKMAEELGQGLKHLAQEVAKAVVGERDRGHGRSPYLEELTKLANSLPLERLYWHTLDGAFPRFFARVEEEASLDLWREALRGAALEAWKATRRFLGTGARHLKALAQGEQEFGRLLGELGEEVRT
>LR027520.1|VCU54684.1|78788_79301_-|CRISPR-associated-protein-Cse2
MSQGERFLDWLRRLQGQKAWTAARAALRRSLAFPPGAYPRAMPYVEPFLAKGDWRREEREAHYLVAALYALKDGDHQVGRTLAQALALRKNATGSASVEKRFLALLEADRDQIAFRLRQAVALVEGGIDFARLLDDLLRWFSPERHVQARWAREFYGAEASEEEKKEVEA
>LR027520.1|VCU54683.1|77676_78792_-|CRISPR-system-Cascade-subunit-CasC
MKLLEVHILQTVAPSNLNRDDTGSPKDALFGGFRRARISSQAQKRAVRVAFRDWPLLSEEERAVRTKRLVEELLRRLAGVEEELARRAIENALNALGFGVKEGRTEYLLFLGNRELDALAQGIRENLEALSGEVKGKKKAEVPSELKKALERVLDGGKAVDLALFGRMLADRPELGVDAAAQVAHALSTHKVDREFDFYTAVDDLNPKEDTGAGMMGDVEFYSATLYRYAVVDLDKLVENLQGDKELALKGVLAFLEAFALTLPSGKQNSFAAHNPPLFVAFRAGEGMPRNLATAFEKPLRPREDKALSALSVERLVQEWARFDKVYGPLNPEWKGALDLTEAEVEGLPKLESFPELRKKVEEALQALLEV
>LR027520.1|VCU54682.1|77219_77675_-|CRISPR-system-Cascade-subunit-CasD
MPTLLLRLQGPMQSWGTRSRFDHRDTWPYPTKSGVVGLLAAALGRDREQDVSDLAALRMGVRVDYQTAQSVLTADLKGKGNVQSWRYYLADAAFLVGLEGERALLETLHGALRNPRFPLYLGRKSYVPSPPPYLPDGLVEAPLAEALEGYS
>LR027520.1|VCU54681.1|76376_77210_+|hypothetical-protein
MLSRLIAAFCIIDDALQAMGYKDDPQAKTPASAILTLALLAALEFGGKHNKALALAKDLGLFTHVPSPSRFNRRLHALYPLLLPLLHLLAQVWKHLHQAQAYALDTFPLPACENIRAPRSRLFPDKAYRGFIPSKRVYFHGLKLHLLVDDGKFVHEVNLTPGSFHDLASLLLLPLDLPEGAELYLDRGYESHLYEDLLREAQEVVPMVIRRRNSRRYLPWMQYLAIVGRRVVETVGSMLHHLFPRRIHAVTQEGFVIKVLTFVLAHNISLLTQKMAG
>LR027520.1|VCU54680.1|76125_76335_-|hypothetical-protein
MGYSYLLGGKPSEDLLLVLEAEEGRLVYDQPAGPFSERRFAARYVREEVLSREAVPGGPPAWEVDRVAQ
>LR027520.1|VCU54679.1|75503_76139_-|CRISPR-associated-endoribonuclease-Cse3
MWLSKLVLNPASRAARRDLANPYEMHRTLSRAVSEALKEGRERLLWRLEPTRGLEPPVVLVQTLTEPDWSVLDEGYAQVFPPKPFHPALKPGQRLRFRLRANPAKRLAATGKRVALKTPAEKVAWLERRLEEGGFRLLEGERGPWVQILQDTFLEVRRKKDGEEAGKLLQVQAVLFEGRLEVVDPERALATLKRGVGPGKALGLGLLSVAP
>LR027520.1|VCU54678.1|74516_75494_-|CRISPR-associated-endonuclease-Cas1
MPPVPSARNLKELPKFRDGLSYLYVEHAVVEREAGGIGIYDQEGLTLAPVAGLGVLFLGPGTRITHAAVRLLAENGCTVAWVGEGMARFYAQGLGDTRSAARFYRQARAWADPALHLEVVMRLYRMRFSEPLPEGLTLEQVRGLEGVRVRNAYARWSRETGVPWYGRSYDRGNWRAADPVNRALSAGASYLYGLAHAAIVSLGFSPALGFIHTGKLLSFVYDIADLYKADYLVPAAFRTVAESEEAVERRVRRALREAIQEGRLLERMAEDLLNLFRGLGLPEEEDPVEEDPTRPGGLWDLEGEVEGGVAYGGDDPGEGAEEPEG
>LR027520.1|VCU54688.1|85309_86254_+|hypothetical-protein
MKRNAWEVYGEVLKTARELGLEGEEQEVAKALLAWPKERFRAFAARVGLKAKYLRHDLLPIALLPEPLREALQKGLPLREAHRLHRLLKRGDLSLQDLTGKDPKALMALPARPGEVDPRLPVWFFPPEPWEEALPLAVAQALVRLYTKEGELVVDPMAGRGTVVEAARALGRRAWGGDIAPRSPLVERADIRDLPQRFRKEAALVVLHPPTFSTWLREEGYREEAEERYGEYIRHISSFLDLCRPTLASGGKLVLVARPRRALTRKDLEAGHDFFLAPWERALAEADFLPLCYHLAVSQDGRQDWHLFVGEVRE
>LR027520.1|VCU54689.1|86250_87126_+|hypothetical-protein
MRLNLSFELPPALEVEMAYTGWGYDPEMEALWRELVEAYAPLAHGIPIRWRVGAKVHQAAAWRKEKGVWTVELSPLLFSRYPIFLARRYGLPMGLPPLHALVRVLEEEGRAAPLPLEGAFWKLARSREPVMALVAYAASRPKAPLPFLVEMAVGNPQALASYLGALEAVEGRDLARSLAAHPLLGPVFAFALEEAGGVSPPAPAEEGLPDLPPPSPKPHRPLFGPPHAGASEEDPAWKTLYDALLRAGGTEDPWEALLEWRDYWYWRGRGEALPSDGKETPGEDGNGGAHE
>LR027520.1|VCU54690.1|87118_87493_+|hypothetical-protein
MNRFAKPKQPSELGLRVSRGVVGGKDLLRVELTAPERPPLTPDLALVLDRSGSMAGAKLQEAKAAALALLEAFPERGRVAVVAYNHEVEVGGLDRKAARAYLEALKASGRTALHAGWRQGTLVK
>LR027520.1|VCU54691.1|87485_89072_-|hypothetical-protein
MKAKPKAARKRTSQKRAKAFTGVHALLVFPSGEDHKATLDLMRRFSAAVRYAYNRLLEGWSREALKRENGPLCVLFCLNTRYADDAVMKAQALLDSARELGEDPRKVVFGGRGLFEQLKRRHLSGKPLKELKREWKEKRQGLLYSRGDKTKGGNLNLRFLVKEGALWLRINLGDGSYAHALVKTSHPNLNALVERVHASLPYNVELSLKDGKVHATFTWEEEPAPLVATKENGVLGIDINADPYHLALALVSPDGNLRRYLTLSLEEVDQAPNKGAKELLLWKVAHQVVSLALEHGVAIATERLKHLPKGRRGDGSGRAFRRKTHRFAYASLLRKVHSLARKKGVQVVEVNPQDTSTIGMLKYAPQLSLSKDVAAAYVIGRRALGFAEKLPRGYGRLLRDQSFRDHVQGFYASRVRELRAKKAREQNPYLRRRLSREIGKAKRHLSLLSSLQGSPGSQEGSTDGRNSPGVNPWRVLRVGTFLPLLGREVPRDLSPLKPILFGGSWEGWKGGLGPHPGGGPECANVRST
>LR027520.1|VCU54692.1|89174_90005_+|hypothetical-protein
MKWCALFPNCLHLLLGDRTRPRFLFLLSDGLANEGLTDLEALAREAREAARAGVYTFTLGFGEGYDRALLARMAREGGGVHRYVAEGELQGALAEELAFLKGPANLGVRVALGGAEVHLAPFAPKEARVLLLPVEEARTLEVEERLPGGAVLYRLPLPGPAPEGSEAWREVELEALLAEGGRLLEREAASAAEAQALAEEAKELALRLQAHPLGESDRALALLTVLEAFRKAMERLAARYEAWASDRVAREGTAYAAHLSFPQRLARLRYRDRTKA
>LR027520.1|VCU54693.1|90038_91157_-|hypothetical-protein
MWNHKPPSITPRLSAWAQALFPHLRRTFRTNLALFLSTLLRHTPPRPTLSAYARSLPLPYSAQAKLNRLWRFLRHPALQNPWILTRALLPLLAPRAAKGKLLPLLVDWTPLEDGKHQALVAALPLRGRALVVAFEVHPRSPWPSASRVEARFFYRLTAWVKELGFVPLFLADRGFDATALLKQLKDWGAAFLIRLEGTVSVVSEEGERFVLKARYPRVPAPFSFRAKLKGAVPVHLFLSQEGEEPWYLALSLPQGSFFEPLGYALRMWIEEGFRDLKGAGLGLDRHLLRTQASLVGWLSLLFLAQVLLVLLGARLEGRPWLHRLVAHPKRQSLFTLGRLALTQPPPKLKGRILRLFYRVLAELAAGKGRTQK
>LR027520.1|VCU54694.1|91271_92252_+|HTH-type-transcriptional-repressor-PurR
MPSGKPLTIRDLAKAARVSVATVSRALNGRPGVSQATRERILALAREWGFVPNAAAREMVGVATAVGILFAPGVRRHTPYFTLLLEALSEALWREGLRVAEVEVDPKGKPRQEALGYILLGAHEGDRRVEALSREGVPFVLVGVGEGIPWVAPQDVEGGYLATRHLVDLGHRTIAHLTGYPEHQAGRERLLGYRKALAEAGIPFREDLVLDGAFDPLTAYRTVRKAWEQGLRFTALFAASDEMALGAWAALEDLGVRVPEEVSLVGYDDLPEFGERLTTVRQDIPTIARKAVALLLEARDGMPPRGLRVPVRLVVRGTTRRREVGA
>LR027520.1|VCU54695.1|92319_93552_+|Maltose-binding-periplasmic-protein
MKKAFLALLALLGLAFAQTQVRISGWGGTDIAIVSGLLKEVVQPKLDKEGIRVVYEPIEGDYTQWLFNALSAGTAPDLFYVDVFWSESLFATGRVEPLDAYFSKQEIAEFLPNLIQAFTYRGKLYGIPKDFNTLALQYNTDLFDEAGVAYPNQQDTWETFEAKLRQVQAKLKDVAGLCVVPDFARFGAFAFATGWKPFDEKGRTVLDQNFRRAFEWYTGLVKRGAARVAQDLGEGWTGGCFGSEKAATALEGAWIAGFLRDKAPNLPYRTTFLPLDPVTKKRGNFIFTVSWSLNAASKNKEAAVKVLKALTSPEAQQWVLERGLAIPSRKALANNPYFQRAGKEPELNRVVFQGSLAQGGHVYPFKFLAYGGDWMRPINDALQAVMTGQKSVDQALKEAQAALDRLTGRR
>LR027520.1|VCU54696.1|93599_94706_+|Lactose-transport-system-permease-protein-LacF
MRLKARTLEALYALLLLFPFLFTLAVFFLYAFVRALYFSFTDYDLFSPPRFVGLANYLSLFRDPFFLTALGHTLAYSFVVTTLQTVLALLVAVALNQPLRGIAFFRTLYYLPSVVSTAAASLLLLWLFQRTGLVNQALSLLLGHLPHLGAFALFFLAFQTAQVFWERRRGVPVPFFDPALALLSAPLALLAAWGLGAAGVLVPREVRVEIPWLPTTATFLGIPYPLWAIILMNTYTTVPTFMVLFLAGLKGIPKTLYEAAALDGATPWTMFTRITVPLLRPVLFLVITLGLIGTLQLFDQVLFVGGSGGAPLEATITLAYYVYGNVFPSGATPRVGLASAAALFLAGLTLVIVLLQRRFGVGERGWSA
>LR027520.1|VCU54697.1|94702_96067_+|L-arabinose-transport-system-permease-protein-AraQ
MSPREAARRRWARVAWVYGLLLAFGVFFVGPFLMGFLASLKPNPLEWPFTLRFAQVSPKNWAAAWRLGRAGSGDPWLGGMRPGREVVLEVAYFWPEDTPPPLEATVPRRRPGAGMGAVFETPYAADHVRLLGPELVEKAPARLGEGEGYVYRFRLRVDYPGEGPFLERVPLDIQAPRGALYLGATLDPTRFERRGRVASWDNVVPGLLGYVFHNYVRAFREARSLETGESLFLRWTLNSFLLAAVKVATTLVFASMAGYALARLRFPGRQALFLFMLFSMMVPGQVTFISNYLVLRDGIFGLSKLFGVETLLNTYTGLILSGLVGAGAVFIMKQFFESIPREVEEAALIDGATPWQTLFRIVLPMSTPALGAVAILTFQGTWNEFFWPFVVLTSPREIYTLPLGLLSFRNAYGQVGDWGLILAGGFFSMVPVLILFAVFQRYFVEGVSVGALKE

Crispr_ID: LR027520_3

• CRISPR_ID: LR027520_3
• CRISPR_location: 310194-310301
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,cas4,WYL,cas8b5,cas7,cas5

Consensus repeat of LR027520_3

Consensus_repeat	Method
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CRISPRCasFinder

spacers of LR027520_3

>3.1|310230|35|LR027520|CRISPRCasFinder
TCACCGCGCCGCGCCTGCCATGCCTCGCCCTGCCC

CRISPR arrays and Neighbor proteins around LR027520_3

CRISPR arrays

The CRISPR arrays of LR027520_3

>merge|LR027520|3|310194-310301|CRISPRCasFinder
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAACTCACCGCGCCGCGCCTGCCATGCCTCGCCCTGCCCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACT

>LR027520|3|3|310194-310301|CRISPRCasFinder
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCACCGCGCCGCGCCTGCCATGCCTCGCCCTGCCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
LR027520.1|VCU54940.1|301926_302502_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54942.1|302712_304302_+|Ribonuclease-J	unknown	unknown	gnl|CDD|293818
LR027520.1|VCU54948.1|309411_309825_+|tRNA(fMet)-specific-endonuclease-VapC	unknown	unknown	gnl|CDD|224761
LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein	cas7	cls000038_cas7_CAS-I-B	unknown
LR027520.1|VCU54949.1|309849_310182_+|hypothetical-protein	unknown	unknown	gnl|CDD|376773
LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
LR027520.1|VCU54941.1|302504_302702_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54944.1|306081_307095_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54951.1|310870_311392_-|hypothetical-protein	unknown	unknown	gnl|CDD|379282
LR027520.1|VCU54950.1|310349_310874_-|hypothetical-protein	unknown	unknown	gnl|CDD|315923
LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
LR027520.1|VCU54945.1|307297_308953_+|hypothetical-protein	unknown	unknown	gnl|CDD|226003
LR027520.1|VCU54947.1|309184_309415_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
LR027520.1|VCU54955.1|316385_316844_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54946.1|308920_309109_-|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	unknown
LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	unknown
LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
LR027520.1|VCU54943.1|304409_306038_+|hypothetical-protein	unknown	unknown	gnl|CDD|227708

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	3.6e-24	79.5	0.0
LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein	cas7	cls000038_cas7_CAS-I-B	1.6e-152	501.6	0.0
LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	4.3e-101	332.8	0.0
LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	3.9e-168	555.6	0.0
LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	1e-141	465.7	0.0
LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	2.8e-35	116.8	0.0
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	2e-42	139.9	2.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
LR027520.1|VCU54945.1|307297_308953_+|hypothetical-protein	gnl|CDD|226003	COG3472, COG3472, Uncharacterized conserved protein [Function unknown].	4.56104e-22
LR027520.1|VCU54948.1|309411_309825_+|tRNA(fMet)-specific-endonuclease-VapC	gnl|CDD|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.62294e-07
LR027520.1|VCU54949.1|309849_310182_+|hypothetical-protein	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	4.24143e-15
LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.78454e-25
LR027520.1|VCU54942.1|302712_304302_+|Ribonuclease-J	gnl|CDD|293818	cd07732, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Includes functionally uncharacterized Enterococcus faecalis EF2904. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.27985e-46
LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.21535e-34
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.77582e-39
LR027520.1|VCU54951.1|310870_311392_-|hypothetical-protein	gnl|CDD|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.00578e-16
LR027520.1|VCU54950.1|310349_310874_-|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.69218e-17
LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.24555e-114
LR027520.1|VCU54943.1|304409_306038_+|hypothetical-protein	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.36259e-54

Protein sequences

>LR027520.1|VCU54949.1|309849_310182_+|hypothetical-protein
MLALLAPELWGRAKRAASYAGLIPEREASGKSVERSQLSRKGPPLLRRKLYMGALVAVRHDPEMRAFYHRLLSRGKRKKQALVAVAHKLLRRMMGRLREYYAGQPAQGVA
>LR027520.1|VCU54948.1|309411_309825_+|tRNA(fMet)-specific-endonuclease-VapC
MIPERLVLDAGPLIALLHRSDPDHEEAVRGFRRLAEGGARLFLPMPVLFEVFKWLLFQAGPKAAREGLAKVEEGVVVVPFTLEDLEEVRLLLARLPGWGGTLEDAGVALLALRLGAPVWTLNYRDLGAFPALRFWTP
>LR027520.1|VCU54947.1|309184_309415_+|hypothetical-protein
MMMCDMRVTIYLPDHLAQEVEAYRKARPGLSLSALVRELLERELVKRPEALLEVAGLVERAELSAREHDALIREER
>LR027520.1|VCU54946.1|308920_309109_-|hypothetical-protein
MRLEGSGAWATAEVQVEALPARVVLSACSEGGACRSLALPREGGPFRLEGLSLAAKLLRYFC
>LR027520.1|VCU54945.1|307297_308953_+|hypothetical-protein
MSLTPPAPPSTTKPSTRFLLLPAPLTHAYSVLDGQQRISALYYAFHHPNLPLPPKGKVVRFFLKLDPFLKGDFDEAVVVERNGSPGFKDLVDEWYRGEALPFGPISGPHPPHLITLYDLLMAPGPSAGSLLDAYLSGTSSPYAPSFGKLFGSLNSLLHYDLDAVVLSFSPGTGSSAIVSAISPVFVNVNSKGTKLTLFDLAVAHLFPLLHPIGLNLRSLWNRLPTTHPGLAGPISKDFVEPDDILRVMAMITGGSVKKATLLNHLHGVVSRLTGASPGGPVTSPAGHSFSSFLDLWDEAASCLEEAYERIVKDYGALGPEWIPYGAMIVPLAALIHVERRSGAPGARDKVDCWYWHSVFYERYEKSVDTTAMADFRAVTSWILGRGGKPSWLPGSVPPGMDLKTVVDRKSALYSGVLNLIALAGARNLVYGSPRGSSLQIDHLFPKGRSKPWATHPWMESVLNATLLDESTNKAKGKKDPSDFYHADVLPGHGKTGASVRDTFGSHLISPAAESSFAHGSSGAPNSVAIFEDFIREREKDVLAEIAKKLSC
>LR027520.1|VCU54944.1|306081_307095_+|hypothetical-protein
MKGIIPIAVYNLGSPEGKGLNFAREELYRRMDAPMMNLAVRIPVYLVNEAQMDRLYPPERRRFFPEEPLRRRLRELRERKPLDDEDPFAPLEDLDRWGEDLWHRVKDVVAVGLYVRGSAMGAQERAFRQEVLRLGEEEARTEGAEEAFLDHEGPVIFLCPERVVGWAAKRGVRVALVQDKVYYHELGHALMDTADPYPDPYGESWGRVVEESLANLVAWMRFRGKEAAWVARLIQDQPPEYRGYAAAAALPHPLFWPEIAHLRVPWEYWEEWWWRYRHFLRGIPGRLRTFLELPFSPDGGSGLYRAWRESKRRGLWREPATQRFWRGVARLLLEEGV
>LR027520.1|VCU54943.1|304409_306038_+|hypothetical-protein
METTPNLQVYDLGHLGLVASIVDQIGLVQTVDQFVGPRPGEKVSTGMALKAAILNALGFVTSPLYLFGHFFQGKPTELLLGPGITPELLNDDRMGRMLDSLYAAGVTELFVEVAKSARRAFPFPVRALHVDSTSFHVHGAYRSGEEGQTDTGDEPLVIRLTHGYSRDHRPDLKQWVMNLICADTGGIPLLFAPGDGNQSDQEALVPLLARYRQGLELGEVVVLDGASYSQENLGALQGFSWVMRVPATLKEARALLRKELPQEAWRPLLPGYRGLEVESEYGGVRQRWLLVESQERARMEEASLRQRIVRAEGEARKVLGRLTARTFACEADARRALSEASGRLPLHRLVYLGVQEERQWERVGRPRKGERPLAVVYRLRARLEVDQEKLERARRGLGRFLLTTNVLDREGLPPQEVLRRYKDQARTVERGFRFLKDPLFFAESTFLKRPERVMALGMVMALALLVYALGEWALRRRLWEAGSSLPDQKGRPTAKPTLRWVFQLFMWVRLVELGGKWFVLNLAPHHETAVRLLGAGRYYLLE
>LR027520.1|VCU54942.1|302712_304302_+|Ribonuclease-J
MRRLDLGRLSVWLFGGLGEIGGNQVLLYTEEGGLLLDFGRPFGRWGAYFTEFLSPRTSGLGLRDLLFLRLLPPVPGLYRDGTGDTLLPTELERELLGGLPLDGGKVLALLLSHAHLDHTGSVGYLRQDLPVVTTAATAAIVKAMQDTAQVGVDGEAAYLSPRLPRGDTGLLEGDRKRYLRRPYRLWGRLQAFPHRSPAVQKTLEGHPWEEASSPLALGPFRVEALPVDHSVPGAAAFAVDTPEGLVVYTGDLRRHGRWGAKTEAFLRGLEGREVFLLLVEGTRLGEPGRARTEEEVRQALHAEVARWEGAPVVVDFAPRNLERLLSALEVAQEVGRRLVVTAKDAYLLWGLAEAEPDPWERVLGEVLVLKEDKNRTSGWERALWDEAPVQGVSPEEVAQDLGAYLLALGFYEVNRLLDLRLLERKAGRVPRRGAYIFSNSYWADQEQILDLKVLLRWLEALDLHLLPEDLAALPQDPQGVRNPFHTSGHAPEADLREVAERLRPRYLLPIHTERPERWREFYEGEVLLL
>LR027520.1|VCU54941.1|302504_302702_+|hypothetical-protein
MAIASVRRRGNYLDVYDERGRRIGGFGISTQDELLGWTADTVIVRRGRTVYHYDARGRVKGTRPA
>LR027520.1|VCU54940.1|301926_302502_+|hypothetical-protein
MEGRGAGRKVGRAALVLLFAALITGAASWTEGPGPFRVRTFVDEIDAGGWLHDMAYGAGVFVVVGPFRILVSKDGVHWKKIHAPARMNAVEYTEVGFLAVGNAGTLMASKDGWDWKRYKVGRDLEWDLFGVAYGGGWYFVAANEGVILASRNLRDWVRLLEDPYMTGMVYGNGRLVVGSLWKLHVVEPGRR
>LR027520.1|VCU54950.1|310349_310874_-|hypothetical-protein
MRLLAYDEHRLGLKPVYRRVWARRGERPLAVGAHRYRWFYVCTFVEPETGESLSLLVDGIDTEVMGWVLRELRAWLGEGEEAWVVLDRAGWHVSGRVEVPEGVRLVFLPPYSPELQPVERVWPLVNEAVANRYFRDLEEMMEAVAERCRVLAQDPETLRRHTLFHWWPRTKELA
>LR027520.1|VCU54951.1|310870_311392_-|hypothetical-protein
MTVADHLTLNELWRRVKKAKDPIEKHRFLAVYHAKRGLTAKEIAKITLSSIRWVQETVRRYNREGPEGLRDKRHQNPGQKPKLTPEEQRRVLEALQGPPPDGGLWTGPKLRDWVERELGKKLSLYPIYRLLHEMGFALRVPRPRHAKADGEAQEAFKKTSPPRSRRRGPRGGR
>LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2
MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV
>LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1
MGVVYVLENEAYLSKEGGTLKVSRRAGREVLLQKPLIAVEEIVILGNAVVTPALLKHCAQEGVGIHYLSRTGTYYAGLTRTPSKNAPARVAQFKAHLEPTWKLALAQRFVLGKIRNGLVFLRRNGAEGWEGLKEALLEAERAQDEEALRGAEGRAADLYFRAFAELLPEEFAFGERSRRPPRDPANSLLSLAYTLLAKQCESALLVAGLDPYVGYLHEVRYGRPSLALDLMEEFRSVLADSVVLSLLNNRRVTLEDFDDSEGFPRLRKEAWPKFLRAWEERLNERVQHPLLGKRLAYREILLAQARILVKHLLGELPRYEPFAVR
>LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion
MGHGGAVEYLPLSKVNTVVYCPRRFYLEYVLGEAHANHHLIEGHYLHERAYTEPGEESGLWVWSDRLGLLGVVDRLEWRRGEACPVEYKLGRAKEEAYLSDAVQLAAQALCLRESRGIEARRGFVYYHKSHTRREVVFTLELFRAVEAAVVRMRALLRSPRPPRVEVPPSKCEGCSVRGACQPELWRKGVAGWA
>LR027520.1|VCU54955.1|316385_316844_+|hypothetical-protein
MRLWWTLALLALGLAACSSGYNASGTWEGVATNRNYPYDAATVRFILHDQGGVLSGSHYALLDAGWTYVGEVRGTRSGQEASWRVDAPNGYILVEGAFQGEAFRGTYTVAVYGSGNLTATLFLSRARVQNLGFPHGKGPLAQQMAALLEEER
>LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein
MVEWAQAMESRLPDFLRLLRENPRGLPVREIAARLGVRRQSVYRLRDKAQSLGVWVETHGENPEVPPGWMRLEAPLEVTVRLTLEEAEALRAAVERMEPLTPLAKRALERLALRTLAAPGKDRQDPVVYTPLADEYPPGLFERAVRAIRERRTCQVTYKNAKGEVKTYRFDPYALIARDPHLYLVGANHNSRRAGHDPVKDLRLDQILDLRLTRERFRKPRFDVRAYAQHRFRAFAGEGAPVRVRVRFSPEKAGFIRRTRRHPTQVVEDLPDGSVVWQVEVPLSEDLVHFIVGYGPHATVLEPEELRRRVVAWAKGAVEANATLIVFQHRRY
>LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein
MVNSCHTDYLAQAKKVAADVKAGLATKEALLSFLEAASDPRFSTYLERLDPNLFRFINLVVKGRVSGKPVLHSPQGTVHTLYVSPFPREGQLRVAYEVGLNGFLEYLESKGYAVLEKRETWLKLYEPRRSYLRSLKEGIQKAWEEYLSQILSLESLLNNLGVLISSLKRLGLSLSDSSRAGSGISLPDVPVPNKGVAFFLLAWCLAEEQISESDLGQLPSEKRALVKEAAEKLKGGRGRYLLGKSYAKAIRKRAKELIRCVEDNSFDPWPRCVLSPEVPFLLLRDAGDAQGSICYGCGHALPRSGGSLRAYKISKIVFSKPTVRRQSDYDGTDNKARICDLCAVLSLASPLKLAQGSVLVRVGHLDEGEIARHFVRSAVLGTLHVAAGRYIQLNSPILTRKSKPLAQELGRVVYALQALGQEVNPKVLERFPFYLVEGAQEIPLPPRALWLSHVLQRAFASRPDEGGEVNRPLGEALRYALGDLPWHALYTLARRYGRVADRFSLEDGLMRYASLLEKEVGMKENTDLSQRFRDVAGLTGLLSAWVGYVEGQVGRNSQEAKRAVVKLLDNLERPGDFLYVAAYHLDSTQARLYEAGGAFFYQEAKRLLQEAGARAQEAEEGSGRFLNVSQDDLHRVYAHLAARYPGKAWEGFIYEVRLSLASRFPQYIRMEKEG
>LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein
MASGLTPKGEALYHWDIYALLYAPQEVYFGHETQVNVNLIETVSLPDGSERVYLSPTKRRGVERRALLYAPVERNGQHLYLTDLLNCGIPNTCGRENCPVCRVYGALVTERRGNIERTTFIGRLTHGGGVSIPAWQPLEKQRAMHPSDLRRESGEEPQPFRRQYGAPGLLFPVYNHVLAASEREFRAVAYAFLASLPRLGAGNPKGLDLYEDETFGPYLVLDRYKAPLGRRVVLPPTLKDPGEALAEFRRRAEDAPEGGALFQRHRGRAALEALRRLAKAFVEEDLPALASAS
>LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein
MYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS

Crispr_ID: LR027520_4

• CRISPR_ID: LR027520_4
• CRISPR_location: 311417-314211
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 38 spacers
• Cas_protein_info: cas2,cas1,cas4,WYL,cas8b5,cas7,cas5,cas3,cas6

Consensus repeat of LR027520_4

Consensus_repeat	Method
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	PILER-CR
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CRISPRCasFinder
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CRT

spacers of LR027520_4

>4.1|311453|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CTTCGGGGCAGGAAACCCGGTGAGCACGGGGAGCGT
>4.2|311525|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
TCACCTGGAGGCGGAAGAGGGCGTTCACAGCTTCCT
>4.3|311597|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
GGAAGAGGGCCAGGGGGCGGAAGAAGAGGGCGGCAAA
>4.4|311670|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCCAGAACTCCCACAGGGCCTCCACCCTGCCCTCCCT
>4.5|311743|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
TATAGCCCCCGAGTGGAGGCCGTTCTGGAAGTGGAC
>4.6|311815|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
ACCCCAACGTGCTCGCCGAGAGGCCGGCTCCCCAACC
>4.7|311888|34|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCAGCTCGTTGGTCCTCTCCATTGAGGGGACCTC
>4.8|311958|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCCGGAGGAGCGCCTTGACCCGCCTATGCCCCCACGCC
>4.9|312032|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
TGGGGGGTGCAGGGGGGCGTCAGTCCCCCCTGCCTGCA
>4.10|312106|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCACCTGCATGCTCACCTCCAGGCCGGGTGGTAGGC
>4.11|312178|35|LR027520|PILER-CR,CRISPRCasFinder,CRT
TCTTCACGCTCACGCTCCCAACACATCTCGCAATA
>4.12|312249|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCAGGTAGTGCTCGCCGTCCACGGGCCGGGCCAGGGGG
>4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
TTGGTGGTGGCGTCGGCGGGGAACTACGGGCAGGAC
>4.14|312395|34|LR027520|PILER-CR,CRISPRCasFinder,CRT
TGAACCAGATTCACCAGGGGTGGTGAACCAGATT
>4.15|312465|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCCCCCTGCACCGCCACCCCGGCGGCGATGGAGAGG
>4.16|312537|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
CTCCCGGAGGGCGGGCCACCAGCGCTCCCAACCCGCG
>4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCGGCGCAGGTCCTCGGGGACCTCCATGGCGTCA
>4.18|312680|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
AGGCCTCAGCGTCAGGGCGGGGAACCCCCCGCAAGC
>4.19|312752|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
CTTCGTCTTGAGGCGATGAAGACGTTGGCTCTCATAG
>4.20|312825|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
TCCGCTCGCGGGTCACGGCCTGGACGGCGGTGGAGGA
>4.21|312898|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCGGGGAAGCTCCTCCACGGGGGGGTAGAGGTCGGG
>4.22|312970|35|LR027520|PILER-CR,CRISPRCasFinder,CRT
GTGATACGAATGACTAGACAGGCGCAGGTTCAGTA
>4.23|313041|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCGGGGCAGCTCCTCGTGGGCCTGCTTCCAGGCCAGGA
>4.24|313115|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
AAAAGATGGTCCAAGGACCCGTTGTCCACCACGGGGT
>4.25|313188|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CTCCCCGAGCCGGGTGCCGTCCTCGCCCTTTTTCCG
>4.26|313260|39|LR027520|PILER-CR,CRISPRCasFinder,CRT
GTGTGGCTCAAGCTGGGCTGGTCCACCACCGCCGACTAC
>4.27|313335|40|LR027520|PILER-CR,CRISPRCasFinder,CRT
CAGAGGACGACCCCGTGGAGAGGGCGCGGAGATTTTTTGT
>4.28|313411|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
GAGGGAGGGGGCTCTTCCGCCGCCTCGGGCGGAAGGGA
>4.29|313485|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
GTGAACGGTGCTTAGCGTTGAGCTCATCCACAAGGCC
>4.30|313558|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
CCAGGGCGGTGAAGTCCACCGCCCGCTCCTCCAGGAC
>4.31|313631|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
GCCCCACGAGGGCGAGGAACAGCCGCTTCACACGCT
>4.32|313703|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
ATGCGCCAGACCATAGAGCAGTTCATGAAGCAGTAC
>4.33|313775|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
AGGGCGATGGTCTACGACGCGGACCGCCAGCTCGGG
>4.34|313847|39|LR027520|PILER-CR,CRISPRCasFinder,CRT
GCTCCTCCGGGGGTGGGACTGGCACCGGGGGGTAGAGAT
>4.35|313922|35|LR027520|PILER-CR,CRISPRCasFinder,CRT
GAAGCGCTCACGGCCAAGTTCCAGTCCCGCCGGGG
>4.36|313993|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
TGTCTACCCCCTGCAGGAGGGAGAGGAGGCTGGACTT
>4.37|314066|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
GAGCTTTCCCCCGAGGGCCTCCTCCGCCTTCTTCTC
>4.38|314138|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
GTGGCGGGTGGACCTCTGAAAGGGGGCCACCAGGGCCT

CRISPR arrays and Neighbor proteins around LR027520_4

CRISPR arrays

The CRISPR arrays of LR027520_4

>merge|LR027520|4|311417-314211|PILER-CR,CRISPRCasFinder,CRT
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAACCTTCGGGGCAGGAAACCCGGTGAGCACGGGGAGCGTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTCACCTGGAGGCGGAAGAGGGCGTTCACAGCTTCCTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGGAAGAGGGCCAGGGGGCGGAAGAAGAGGGCGGCAAAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCCAGAACTCCCACAGGGCCTCCACCCTGCCCTCCCTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTATAGCCCCCGAGTGGAGGCCGTTCTGGAAGTGGACGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACACCCCAACGTGCTCGCCGAGAGGCCGGCTCCCCAACCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCAGCTCGTTGGTCCTCTCCATTGAGGGGACCTCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCCGGAGGAGCGCCTTGACCCGCCTATGCCCCCACGCCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTGGGGGGTGCAGGGGGGCGTCAGTCCCCCCTGCCTGCAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCACCTGCATGCTCACCTCCAGGCCGGGTGGTAGGCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTCTTCACGCTCACGCTCCCAACACATCTCGCAATAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCAGGTAGTGCTCGCCGTCCACGGGCCGGGCCAGGGGGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTTGGTGGTGGCGTCGGCGGGGAACTACGGGCAGGACGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTGAACCAGATTCACCAGGGGTGGTGAACCAGATTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCCCCCTGCACCGCCACCCCGGCGGCGATGGAGAGGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCTCCCGGAGGGCGGGCCACCAGCGCTCCCAACCCGCGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCGGCGCAGGTCCTCGGGGACCTCCATGGCGTCAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACAGGCCTCAGCGTCAGGGCGGGGAACCCCCCGCAAGCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCTTCGTCTTGAGGCGATGAAGACGTTGGCTCTCATAGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTCCGCTCGCGGGTCACGGCCTGGACGGCGGTGGAGGAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCGGGGAAGCTCCTCCACGGGGGGGTAGAGGTCGGGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGTGATACGAATGACTAGACAGGCGCAGGTTCAGTAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCGGGGCAGCTCCTCGTGGGCCTGCTTCCAGGCCAGGAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACAAAAGATGGTCCAAGGACCCGTTGTCCACCACGGGGTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCTCCCCGAGCCGGGTGCCGTCCTCGCCCTTTTTCCGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGTGTGGCTCAAGCTGGGCTGGTCCACCACCGCCGACTACGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCAGAGGACGACCCCGTGGAGAGGGCGCGGAGATTTTTTGTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGAGGGAGGGGGCTCTTCCGCCGCCTCGGGCGGAAGGGAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGTGAACGGTGCTTAGCGTTGAGCTCATCCACAAGGCCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCAGGGCGGTGAAGTCCACCGCCCGCTCCTCCAGGACGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGCCCCACGAGGGCGAGGAACAGCCGCTTCACACGCTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACATGCGCCAGACCATAGAGCAGTTCATGAAGCAGTACGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACAGGGCGATGGTCTACGACGCGGACCGCCAGCTCGGGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGCTCCTCCGGGGGTGGGACTGGCACCGGGGGGTAGAGATGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGAAGCGCTCACGGCCAAGTTCCAGTCCCGCCGGGGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTGTCTACCCCCTGCAGGAGGGAGAGGAGGCTGGACTTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGAGCTTTCCCCCGAGGGCCTCCTCCGCCTTCTTCTCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGTGGCGGGTGGACCTCTGAAAGGGGGCCACCAGGGCCTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

>LR027520|4|3|311417-314211|PILER-CR
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTTCGGGGCAGGAAACCCGGTGAGCACGGGGAGCGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCACCTGGAGGCGGAAGAGGGCGTTCACAGCTTCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGAAGAGGGCCAGGGGGCGGAAGAAGAGGGCGGCAAA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCAGAACTCCCACAGGGCCTCCACCCTGCCCTCCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TATAGCCCCCGAGTGGAGGCCGTTCTGGAAGTGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ACCCCAACGTGCTCGCCGAGAGGCCGGCTCCCCAACC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGCTCGTTGGTCCTCTCCATTGAGGGGACCTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCGGAGGAGCGCCTTGACCCGCCTATGCCCCCACGCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGGGGGGTGCAGGGGGGCGTCAGTCCCCCCTGCCTGCA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCACCTGCATGCTCACCTCCAGGCCGGGTGGTAGGC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCTTCACGCTCACGCTCCCAACACATCTCGCAATA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGGTAGTGCTCGCCGTCCACGGGCCGGGCCAGGGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TTGGTGGTGGCGTCGGCGGGGAACTACGGGCAGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGAACCAGATTCACCAGGGGTGGTGAACCAGATT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCCCCTGCACCGCCACCCCGGCGGCGATGGAGAGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTCCCGGAGGGCGGGCCACCAGCGCTCCCAACCCGCG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGCGCAGGTCCTCGGGGACCTCCATGGCGTCA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AGGCCTCAGCGTCAGGGCGGGGAACCCCCCGCAAGC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTTCGTCTTGAGGCGATGAAGACGTTGGCTCTCATAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCCGCTCGCGGGTCACGGCCTGGACGGCGGTGGAGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGGGAAGCTCCTCCACGGGGGGGTAGAGGTCGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGATACGAATGACTAGACAGGCGCAGGTTCAGTA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGGGCAGCTCCTCGTGGGCCTGCTTCCAGGCCAGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AAAAGATGGTCCAAGGACCCGTTGTCCACCACGGGGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTCCCCGAGCCGGGTGCCGTCCTCGCCCTTTTTCCG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGTGGCTCAAGCTGGGCTGGTCCACCACCGCCGACTAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CAGAGGACGACCCCGTGGAGAGGGCGCGGAGATTTTTTGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAGGGAGGGGGCTCTTCCGCCGCCTCGGGCGGAAGGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGAACGGTGCTTAGCGTTGAGCTCATCCACAAGGCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGGGCGGTGAAGTCCACCGCCCGCTCCTCCAGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GCCCCACGAGGGCGAGGAACAGCCGCTTCACACGCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ATGCGCCAGACCATAGAGCAGTTCATGAAGCAGTAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AGGGCGATGGTCTACGACGCGGACCGCCAGCTCGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GCTCCTCCGGGGGTGGGACTGGCACCGGGGGGTAGAGAT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAAGCGCTCACGGCCAAGTTCCAGTCCCGCCGGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGTCTACCCCCTGCAGGAGGGAGAGGAGGCTGGACTT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAGCTTTCCCCCGAGGGCCTCCTCCGCCTTCTTCTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGGCGGGTGGACCTCTGAAAGGGGGCCACCAGGGCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

>LR027520|4|4|311417-314211|CRISPRCasFinder
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTTCGGGGCAGGAAACCCGGTGAGCACGGGGAGCGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCACCTGGAGGCGGAAGAGGGCGTTCACAGCTTCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGAAGAGGGCCAGGGGGCGGAAGAAGAGGGCGGCAAA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCAGAACTCCCACAGGGCCTCCACCCTGCCCTCCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TATAGCCCCCGAGTGGAGGCCGTTCTGGAAGTGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ACCCCAACGTGCTCGCCGAGAGGCCGGCTCCCCAACC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGCTCGTTGGTCCTCTCCATTGAGGGGACCTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCGGAGGAGCGCCTTGACCCGCCTATGCCCCCACGCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGGGGGGTGCAGGGGGGCGTCAGTCCCCCCTGCCTGCA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCACCTGCATGCTCACCTCCAGGCCGGGTGGTAGGC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCTTCACGCTCACGCTCCCAACACATCTCGCAATA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGGTAGTGCTCGCCGTCCACGGGCCGGGCCAGGGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TTGGTGGTGGCGTCGGCGGGGAACTACGGGCAGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGAACCAGATTCACCAGGGGTGGTGAACCAGATT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCCCCTGCACCGCCACCCCGGCGGCGATGGAGAGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTCCCGGAGGGCGGGCCACCAGCGCTCCCAACCCGCG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGCGCAGGTCCTCGGGGACCTCCATGGCGTCA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AGGCCTCAGCGTCAGGGCGGGGAACCCCCCGCAAGC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTTCGTCTTGAGGCGATGAAGACGTTGGCTCTCATAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCCGCTCGCGGGTCACGGCCTGGACGGCGGTGGAGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGGGAAGCTCCTCCACGGGGGGGTAGAGGTCGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGATACGAATGACTAGACAGGCGCAGGTTCAGTA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGGGCAGCTCCTCGTGGGCCTGCTTCCAGGCCAGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AAAAGATGGTCCAAGGACCCGTTGTCCACCACGGGGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTCCCCGAGCCGGGTGCCGTCCTCGCCCTTTTTCCG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGTGGCTCAAGCTGGGCTGGTCCACCACCGCCGACTAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CAGAGGACGACCCCGTGGAGAGGGCGCGGAGATTTTTTGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAGGGAGGGGGCTCTTCCGCCGCCTCGGGCGGAAGGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGAACGGTGCTTAGCGTTGAGCTCATCCACAAGGCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGGGCGGTGAAGTCCACCGCCCGCTCCTCCAGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GCCCCACGAGGGCGAGGAACAGCCGCTTCACACGCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ATGCGCCAGACCATAGAGCAGTTCATGAAGCAGTAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AGGGCGATGGTCTACGACGCGGACCGCCAGCTCGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GCTCCTCCGGGGGTGGGACTGGCACCGGGGGGTAGAGAT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAAGCGCTCACGGCCAAGTTCCAGTCCCGCCGGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGTCTACCCCCTGCAGGAGGGAGAGGAGGCTGGACTT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAGCTTTCCCCCGAGGGCCTCCTCCGCCTTCTTCTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGGCGGGTGGACCTCTGAAAGGGGGCCACCAGGGCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

>LR027520|4|3|311417-314211|CRT
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTTCGGGGCAGGAAACCCGGTGAGCACGGGGAGCGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCACCTGGAGGCGGAAGAGGGCGTTCACAGCTTCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGAAGAGGGCCAGGGGGCGGAAGAAGAGGGCGGCAAA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCAGAACTCCCACAGGGCCTCCACCCTGCCCTCCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TATAGCCCCCGAGTGGAGGCCGTTCTGGAAGTGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ACCCCAACGTGCTCGCCGAGAGGCCGGCTCCCCAACC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGCTCGTTGGTCCTCTCCATTGAGGGGACCTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCGGAGGAGCGCCTTGACCCGCCTATGCCCCCACGCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGGGGGGTGCAGGGGGGCGTCAGTCCCCCCTGCCTGCA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCACCTGCATGCTCACCTCCAGGCCGGGTGGTAGGC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCTTCACGCTCACGCTCCCAACACATCTCGCAATA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGGTAGTGCTCGCCGTCCACGGGCCGGGCCAGGGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TTGGTGGTGGCGTCGGCGGGGAACTACGGGCAGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGAACCAGATTCACCAGGGGTGGTGAACCAGATT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCCCCCTGCACCGCCACCCCGGCGGCGATGGAGAGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTCCCGGAGGGCGGGCCACCAGCGCTCCCAACCCGCG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGCGCAGGTCCTCGGGGACCTCCATGGCGTCA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AGGCCTCAGCGTCAGGGCGGGGAACCCCCCGCAAGC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTTCGTCTTGAGGCGATGAAGACGTTGGCTCTCATAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TCCGCTCGCGGGTCACGGCCTGGACGGCGGTGGAGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGGGAAGCTCCTCCACGGGGGGGTAGAGGTCGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGATACGAATGACTAGACAGGCGCAGGTTCAGTA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCGGGGCAGCTCCTCGTGGGCCTGCTTCCAGGCCAGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AAAAGATGGTCCAAGGACCCGTTGTCCACCACGGGGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTCCCCGAGCCGGGTGCCGTCCTCGCCCTTTTTCCG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGTGGCTCAAGCTGGGCTGGTCCACCACCGCCGACTAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CAGAGGACGACCCCGTGGAGAGGGCGCGGAGATTTTTTGT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAGGGAGGGGGCTCTTCCGCCGCCTCGGGCGGAAGGGA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGAACGGTGCTTAGCGTTGAGCTCATCCACAAGGCC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCAGGGCGGTGAAGTCCACCGCCCGCTCCTCCAGGAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GCCCCACGAGGGCGAGGAACAGCCGCTTCACACGCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ATGCGCCAGACCATAGAGCAGTTCATGAAGCAGTAC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	AGGGCGATGGTCTACGACGCGGACCGCCAGCTCGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GCTCCTCCGGGGGTGGGACTGGCACCGGGGGGTAGAGAT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAAGCGCTCACGGCCAAGTTCCAGTCCCGCCGGGG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TGTCTACCCCCTGCAGGAGGGAGAGGAGGCTGGACTT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GAGCTTTCCCCCGAGGGCCTCCTCCGCCTTCTTCTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GTGGCGGGTGGACCTCTGAAAGGGGGCCACCAGGGCCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
LR027520.1|VCU54942.1|302712_304302_+|Ribonuclease-J	unknown	unknown	gnl|CDD|293818
LR027520.1|VCU54950.1|310349_310874_-|hypothetical-protein	unknown	unknown	gnl|CDD|315923
LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein	cas7	cls000038_cas7_CAS-I-B	unknown
LR027520.1|VCU54949.1|309849_310182_+|hypothetical-protein	unknown	unknown	gnl|CDD|376773
LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|224124
LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
LR027520.1|VCU54955.1|316385_316844_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54944.1|306081_307095_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54951.1|310870_311392_-|hypothetical-protein	unknown	unknown	gnl|CDD|379282
LR027520.1|VCU54948.1|309411_309825_+|tRNA(fMet)-specific-endonuclease-VapC	unknown	unknown	gnl|CDD|224761
LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
LR027520.1|VCU54945.1|307297_308953_+|hypothetical-protein	unknown	unknown	gnl|CDD|226003
LR027520.1|VCU54947.1|309184_309415_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	unknown
LR027520.1|VCU54946.1|308920_309109_-|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	unknown
LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
LR027520.1|VCU54943.1|304409_306038_+|hypothetical-protein	unknown	unknown	gnl|CDD|227708

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein	cas6	cd09652_cas6_CAS-I:CAS-III	5e-34	113.1	0.0
LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	3.6e-24	79.5	0.0
LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein	cas7	cls000038_cas7_CAS-I-B	1.6e-152	501.6	0.0
LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	4.3e-101	332.8	0.0
LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	5.1e-46	152.0	0.0
LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	3.9e-168	555.6	0.0
LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	1e-141	465.7	0.0
LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	2.8e-35	116.8	0.0
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	2e-42	139.9	2.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.26839e-32
LR027520.1|VCU54942.1|302712_304302_+|Ribonuclease-J	gnl|CDD|293818	cd07732, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Includes functionally uncharacterized Enterococcus faecalis EF2904. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.27985e-46
LR027520.1|VCU54950.1|310349_310874_-|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.69218e-17
LR027520.1|VCU54949.1|309849_310182_+|hypothetical-protein	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	4.24143e-15
LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.42475e-41
LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.78454e-25
LR027520.1|VCU54951.1|310870_311392_-|hypothetical-protein	gnl|CDD|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.00578e-16
LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.21535e-34
LR027520.1|VCU54945.1|307297_308953_+|hypothetical-protein	gnl|CDD|226003	COG3472, COG3472, Uncharacterized conserved protein [Function unknown].	4.56104e-22
LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.24555e-114
LR027520.1|VCU54948.1|309411_309825_+|tRNA(fMet)-specific-endonuclease-VapC	gnl|CDD|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.62294e-07
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.77582e-39
LR027520.1|VCU54943.1|304409_306038_+|hypothetical-protein	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.36259e-54

Protein sequences

>LR027520.1|VCU54951.1|310870_311392_-|hypothetical-protein
MTVADHLTLNELWRRVKKAKDPIEKHRFLAVYHAKRGLTAKEIAKITLSSIRWVQETVRRYNREGPEGLRDKRHQNPGQKPKLTPEEQRRVLEALQGPPPDGGLWTGPKLRDWVERELGKKLSLYPIYRLLHEMGFALRVPRPRHAKADGEAQEAFKKTSPPRSRRRGPRGGR
>LR027520.1|VCU54950.1|310349_310874_-|hypothetical-protein
MRLLAYDEHRLGLKPVYRRVWARRGERPLAVGAHRYRWFYVCTFVEPETGESLSLLVDGIDTEVMGWVLRELRAWLGEGEEAWVVLDRAGWHVSGRVEVPEGVRLVFLPPYSPELQPVERVWPLVNEAVANRYFRDLEEMMEAVAERCRVLAQDPETLRRHTLFHWWPRTKELA
>LR027520.1|VCU54949.1|309849_310182_+|hypothetical-protein
MLALLAPELWGRAKRAASYAGLIPEREASGKSVERSQLSRKGPPLLRRKLYMGALVAVRHDPEMRAFYHRLLSRGKRKKQALVAVAHKLLRRMMGRLREYYAGQPAQGVA
>LR027520.1|VCU54948.1|309411_309825_+|tRNA(fMet)-specific-endonuclease-VapC
MIPERLVLDAGPLIALLHRSDPDHEEAVRGFRRLAEGGARLFLPMPVLFEVFKWLLFQAGPKAAREGLAKVEEGVVVVPFTLEDLEEVRLLLARLPGWGGTLEDAGVALLALRLGAPVWTLNYRDLGAFPALRFWTP
>LR027520.1|VCU54947.1|309184_309415_+|hypothetical-protein
MMMCDMRVTIYLPDHLAQEVEAYRKARPGLSLSALVRELLERELVKRPEALLEVAGLVERAELSAREHDALIREER
>LR027520.1|VCU54946.1|308920_309109_-|hypothetical-protein
MRLEGSGAWATAEVQVEALPARVVLSACSEGGACRSLALPREGGPFRLEGLSLAAKLLRYFC
>LR027520.1|VCU54945.1|307297_308953_+|hypothetical-protein
MSLTPPAPPSTTKPSTRFLLLPAPLTHAYSVLDGQQRISALYYAFHHPNLPLPPKGKVVRFFLKLDPFLKGDFDEAVVVERNGSPGFKDLVDEWYRGEALPFGPISGPHPPHLITLYDLLMAPGPSAGSLLDAYLSGTSSPYAPSFGKLFGSLNSLLHYDLDAVVLSFSPGTGSSAIVSAISPVFVNVNSKGTKLTLFDLAVAHLFPLLHPIGLNLRSLWNRLPTTHPGLAGPISKDFVEPDDILRVMAMITGGSVKKATLLNHLHGVVSRLTGASPGGPVTSPAGHSFSSFLDLWDEAASCLEEAYERIVKDYGALGPEWIPYGAMIVPLAALIHVERRSGAPGARDKVDCWYWHSVFYERYEKSVDTTAMADFRAVTSWILGRGGKPSWLPGSVPPGMDLKTVVDRKSALYSGVLNLIALAGARNLVYGSPRGSSLQIDHLFPKGRSKPWATHPWMESVLNATLLDESTNKAKGKKDPSDFYHADVLPGHGKTGASVRDTFGSHLISPAAESSFAHGSSGAPNSVAIFEDFIREREKDVLAEIAKKLSC
>LR027520.1|VCU54944.1|306081_307095_+|hypothetical-protein
MKGIIPIAVYNLGSPEGKGLNFAREELYRRMDAPMMNLAVRIPVYLVNEAQMDRLYPPERRRFFPEEPLRRRLRELRERKPLDDEDPFAPLEDLDRWGEDLWHRVKDVVAVGLYVRGSAMGAQERAFRQEVLRLGEEEARTEGAEEAFLDHEGPVIFLCPERVVGWAAKRGVRVALVQDKVYYHELGHALMDTADPYPDPYGESWGRVVEESLANLVAWMRFRGKEAAWVARLIQDQPPEYRGYAAAAALPHPLFWPEIAHLRVPWEYWEEWWWRYRHFLRGIPGRLRTFLELPFSPDGGSGLYRAWRESKRRGLWREPATQRFWRGVARLLLEEGV
>LR027520.1|VCU54943.1|304409_306038_+|hypothetical-protein
METTPNLQVYDLGHLGLVASIVDQIGLVQTVDQFVGPRPGEKVSTGMALKAAILNALGFVTSPLYLFGHFFQGKPTELLLGPGITPELLNDDRMGRMLDSLYAAGVTELFVEVAKSARRAFPFPVRALHVDSTSFHVHGAYRSGEEGQTDTGDEPLVIRLTHGYSRDHRPDLKQWVMNLICADTGGIPLLFAPGDGNQSDQEALVPLLARYRQGLELGEVVVLDGASYSQENLGALQGFSWVMRVPATLKEARALLRKELPQEAWRPLLPGYRGLEVESEYGGVRQRWLLVESQERARMEEASLRQRIVRAEGEARKVLGRLTARTFACEADARRALSEASGRLPLHRLVYLGVQEERQWERVGRPRKGERPLAVVYRLRARLEVDQEKLERARRGLGRFLLTTNVLDREGLPPQEVLRRYKDQARTVERGFRFLKDPLFFAESTFLKRPERVMALGMVMALALLVYALGEWALRRRLWEAGSSLPDQKGRPTAKPTLRWVFQLFMWVRLVELGGKWFVLNLAPHHETAVRLLGAGRYYLLE
>LR027520.1|VCU54942.1|302712_304302_+|Ribonuclease-J
MRRLDLGRLSVWLFGGLGEIGGNQVLLYTEEGGLLLDFGRPFGRWGAYFTEFLSPRTSGLGLRDLLFLRLLPPVPGLYRDGTGDTLLPTELERELLGGLPLDGGKVLALLLSHAHLDHTGSVGYLRQDLPVVTTAATAAIVKAMQDTAQVGVDGEAAYLSPRLPRGDTGLLEGDRKRYLRRPYRLWGRLQAFPHRSPAVQKTLEGHPWEEASSPLALGPFRVEALPVDHSVPGAAAFAVDTPEGLVVYTGDLRRHGRWGAKTEAFLRGLEGREVFLLLVEGTRLGEPGRARTEEEVRQALHAEVARWEGAPVVVDFAPRNLERLLSALEVAQEVGRRLVVTAKDAYLLWGLAEAEPDPWERVLGEVLVLKEDKNRTSGWERALWDEAPVQGVSPEEVAQDLGAYLLALGFYEVNRLLDLRLLERKAGRVPRRGAYIFSNSYWADQEQILDLKVLLRWLEALDLHLLPEDLAALPQDPQGVRNPFHTSGHAPEADLREVAERLRPRYLLPIHTERPERWREFYEGEVLLL
>LR027520.1|VCU54952.1|314450_314735_-|CRISPR-associated-endoribonuclease-Cas2
MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV
>LR027520.1|VCU54953.1|314731_315709_-|CRISPR-associated-endonuclease-Cas1
MGVVYVLENEAYLSKEGGTLKVSRRAGREVLLQKPLIAVEEIVILGNAVVTPALLKHCAQEGVGIHYLSRTGTYYAGLTRTPSKNAPARVAQFKAHLEPTWKLALAQRFVLGKIRNGLVFLRRNGAEGWEGLKEALLEAERAQDEEALRGAEGRAADLYFRAFAELLPEEFAFGERSRRPPRDPANSLLSLAYTLLAKQCESALLVAGLDPYVGYLHEVRYGRPSLALDLMEEFRSVLADSVVLSLLNNRRVTLEDFDDSEGFPRLRKEAWPKFLRAWEERLNERVQHPLLGKRLAYREILLAQARILVKHLLGELPRYEPFAVR
>LR027520.1|VCU54954.1|315699_316284_-|CRISPR-associated-exonuclease-Cas4/endonuclease-Cas1-fusion
MGHGGAVEYLPLSKVNTVVYCPRRFYLEYVLGEAHANHHLIEGHYLHERAYTEPGEESGLWVWSDRLGLLGVVDRLEWRRGEACPVEYKLGRAKEEAYLSDAVQLAAQALCLRESRGIEARRGFVYYHKSHTRREVVFTLELFRAVEAAVVRMRALLRSPRPPRVEVPPSKCEGCSVRGACQPELWRKGVAGWA
>LR027520.1|VCU54955.1|316385_316844_+|hypothetical-protein
MRLWWTLALLALGLAACSSGYNASGTWEGVATNRNYPYDAATVRFILHDQGGVLSGSHYALLDAGWTYVGEVRGTRSGQEASWRVDAPNGYILVEGAFQGEAFRGTYTVAVYGSGNLTATLFLSRARVQNLGFPHGKGPLAQQMAALLEEER
>LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein
MVEWAQAMESRLPDFLRLLRENPRGLPVREIAARLGVRRQSVYRLRDKAQSLGVWVETHGENPEVPPGWMRLEAPLEVTVRLTLEEAEALRAAVERMEPLTPLAKRALERLALRTLAAPGKDRQDPVVYTPLADEYPPGLFERAVRAIRERRTCQVTYKNAKGEVKTYRFDPYALIARDPHLYLVGANHNSRRAGHDPVKDLRLDQILDLRLTRERFRKPRFDVRAYAQHRFRAFAGEGAPVRVRVRFSPEKAGFIRRTRRHPTQVVEDLPDGSVVWQVEVPLSEDLVHFIVGYGPHATVLEPEELRRRVVAWAKGAVEANATLIVFQHRRY
>LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein
MVNSCHTDYLAQAKKVAADVKAGLATKEALLSFLEAASDPRFSTYLERLDPNLFRFINLVVKGRVSGKPVLHSPQGTVHTLYVSPFPREGQLRVAYEVGLNGFLEYLESKGYAVLEKRETWLKLYEPRRSYLRSLKEGIQKAWEEYLSQILSLESLLNNLGVLISSLKRLGLSLSDSSRAGSGISLPDVPVPNKGVAFFLLAWCLAEEQISESDLGQLPSEKRALVKEAAEKLKGGRGRYLLGKSYAKAIRKRAKELIRCVEDNSFDPWPRCVLSPEVPFLLLRDAGDAQGSICYGCGHALPRSGGSLRAYKISKIVFSKPTVRRQSDYDGTDNKARICDLCAVLSLASPLKLAQGSVLVRVGHLDEGEIARHFVRSAVLGTLHVAAGRYIQLNSPILTRKSKPLAQELGRVVYALQALGQEVNPKVLERFPFYLVEGAQEIPLPPRALWLSHVLQRAFASRPDEGGEVNRPLGEALRYALGDLPWHALYTLARRYGRVADRFSLEDGLMRYASLLEKEVGMKENTDLSQRFRDVAGLTGLLSAWVGYVEGQVGRNSQEAKRAVVKLLDNLERPGDFLYVAAYHLDSTQARLYEAGGAFFYQEAKRLLQEAGARAQEAEEGSGRFLNVSQDDLHRVYAHLAARYPGKAWEGFIYEVRLSLASRFPQYIRMEKEG
>LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein
MASGLTPKGEALYHWDIYALLYAPQEVYFGHETQVNVNLIETVSLPDGSERVYLSPTKRRGVERRALLYAPVERNGQHLYLTDLLNCGIPNTCGRENCPVCRVYGALVTERRGNIERTTFIGRLTHGGGVSIPAWQPLEKQRAMHPSDLRRESGEEPQPFRRQYGAPGLLFPVYNHVLAASEREFRAVAYAFLASLPRLGAGNPKGLDLYEDETFGPYLVLDRYKAPLGRRVVLPPTLKDPGEALAEFRRRAEDAPEGGALFQRHRGRAALEALRRLAKAFVEEDLPALASAS
>LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein
MYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS
>LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3
MGEGIGRVFFLKDKVGFQPLSNHQGLVVKLLESWREGDEPLALSPKTKERLLLAARYHDDGKRFTFRIVPDGKGGLTYSFRGHRFRVAQAVQDPYAQALIRGHHDYSTREVVNLAADFLEEGLGHRFPEDLFLLMMADQLEAELAVRLWQGQAGEVRPFVEFDLLPDGEGGFLLDPWPFRVDEVALDFLVYFHPYRGEEAEVVEGWGRALVGALEEGKVPEAFREEKRRVHLRPWAAGARKADDPEAFYARFGLKPTPFQREVFKVAEGDPAHLLLAPTGTGKTEAAAFPALARGERLVFVLPTRSLVDDLEGRFRRYLKILAQEEGRPKALVVDTGHRQARFRFSPDGQEEATKERHLYHADVILTTLDKLLYRYFGYAEGVKSYTFPRRIHDRRTLFVFDEVHLYEATAWVNFRHLIASLYKAGVRFLVMSATMPGTYREELLLEGTLEHPPAKRPSRVLRYMPQGNPMEIIQSHRDKRVLVVLEEVKEAAELYKGLKGEGVFLYHGRLAEGQRRRVFGEVKRRDGAQKPYLLITTPAIEVGVDLDAEVLVTTLCPPENLLQRLGRVNRRGRGQGEAYVVGETYPDYLGSLPEGYLELLKALDGQDLAQGGEERLRQAIRYPKYLDPRAETFFEALQEYVYGLDLTQEPLHRKGFVATRGWTPSVRLRQGEDEVEVPIDRLVGRKEELTPVRVVERLLTDGEKGNRRREEVPLRSGELYGRELVLDYPYPYDAELGFVELPKVFQRLRHPDPQRVQLLYAPEKDAGEAPEGVMDTDQVTGGGRRVLWYLGESAWAEPAKSGEVAEETEEEEEEGD
>LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein
MPQAVVLELVGEKPPLYPGRYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRVGPEGATLKGILRLRLTALDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFAYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL

Crispr_ID: LR027520_5

• CRISPR_ID: LR027520_5
• CRISPR_location: 326326-327309
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 13 spacers
• Cas_protein_info: cas6,cas3,cas5,cas7,cas8b5,WYL

Consensus repeat of LR027520_5

Consensus_repeat	Method
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	PILER-CR
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CRISPRCasFinder
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CRT

spacers of LR027520_5

>5.1|326362|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
>5.2|326435|39|LR027520|PILER-CR,CRISPRCasFinder,CRT
GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
>5.3|326510|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
>5.4|326583|39|LR027520|PILER-CR,CRISPRCasFinder,CRT
GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
>5.5|326658|38|LR027520|PILER-CR,CRISPRCasFinder,CRT
AGAAGCGGCTAGGGGAAATCATCAGGGCAGCGCGGCTT
>5.6|326732|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CGAGGATGGCCGGGTCTACCAGCTTTAGCGTAGAGC
>5.7|326804|39|LR027520|PILER-CR,CRISPRCasFinder,CRT
GGGCATGGCCTGGCAAGGCACGACCTGGTGCGGCAGGCC
>5.8|326879|37|LR027520|PILER-CR,CRISPRCasFinder,CRT
TGTAGAGGCCACGATTGCGGTGGACCAGGCAAACCTG
>5.9|326952|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CTCCCCGAGGTAGTAGGCCTCCACGCGCTCAATCAC
>5.10|327024|36|LR027520|PILER-CR,CRISPRCasFinder,CRT
CGGGAGGGCATGAACGCCGTCCTGGCCTGGCTTCAG
>5.11|327096|35|LR027520|PILER-CR,CRISPRCasFinder,CRT
GCCTTTATGGCGGCGCTCTCCATGAGAGCCTGGAC
>5.12|327167|35|LR027520|PILER-CR,CRISPRCasFinder,CRT
CACGGCGCGGACCGCCCAGGACACGCGCATCTGCA
>5.13|327238|36|LR027520|CRISPRCasFinder,CRT
CGGAGGGTGCAGGGCGAGGAGGACGGCCACCTCCCC

CRISPR arrays and Neighbor proteins around LR027520_5

CRISPR arrays

The CRISPR arrays of LR027520_5

>merge|LR027520|5|326326-327309|PILER-CR,CRISPRCasFinder,CRT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACGTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACGTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACAGAAGCGGCTAGGGGAAATCATCAGGGCAGCGCGGCTTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCGAGGATGGCCGGGTCTACCAGCTTTAGCGTAGAGCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACGGGCATGGCCTGGCAAGGCACGACCTGGTGCGGCAGGCCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTGTAGAGGCCACGATTGCGGTGGACCAGGCAAACCTGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCTCCCCGAGGTAGTAGGCCTCCACGCGCTCAATCACGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCGGGAGGGCATGAACGCCGTCCTGGCCTGGCTTCAGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACGCCTTTATGGCGGCGCTCTCCATGAGAGCCTGGACGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCACGGCGCGGACCGCCCAGGACACGCGCATCTGCAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCGGAGGGTGCAGGGCGAGGAGGACGGCCACCTCCCCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGGCCA

>LR027520|5|4|326326-327237|PILER-CR
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	AGAAGCGGCTAGGGGAAATCATCAGGGCAGCGCGGCTT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGAGGATGGCCGGGTCTACCAGCTTTAGCGTAGAGC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GGGCATGGCCTGGCAAGGCACGACCTGGTGCGGCAGGCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TGTAGAGGCCACGATTGCGGTGGACCAGGCAAACCTG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CTCCCCGAGGTAGTAGGCCTCCACGCGCTCAATCAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGGGAGGGCATGAACGCCGTCCTGGCCTGGCTTCAG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GCCTTTATGGCGGCGCTCTCCATGAGAGCCTGGAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CACGGCGCGGACCGCCCAGGACACGCGCATCTGCA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC

>LR027520|5|5|326326-327309|CRISPRCasFinder
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	AGAAGCGGCTAGGGGAAATCATCAGGGCAGCGCGGCTT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGAGGATGGCCGGGTCTACCAGCTTTAGCGTAGAGC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GGGCATGGCCTGGCAAGGCACGACCTGGTGCGGCAGGCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TGTAGAGGCCACGATTGCGGTGGACCAGGCAAACCTG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CTCCCCGAGGTAGTAGGCCTCCACGCGCTCAATCAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGGGAGGGCATGAACGCCGTCCTGGCCTGGCTTCAG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GCCTTTATGGCGGCGCTCTCCATGAGAGCCTGGAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CACGGCGCGGACCGCCCAGGACACGCGCATCTGCA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGGAGGGTGCAGGGCGAGGAGGACGGCCACCTCCCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGGCCA

>LR027520|5|4|326326-327309|CRT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTTCACGGGGTGCGTAGGGGGGTGAGGGCCGCCCAAA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GTGGCGATGGCGGTGGCCAGGCCAAAGTCATCAATGCCG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	AGAAGCGGCTAGGGGAAATCATCAGGGCAGCGCGGCTT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGAGGATGGCCGGGTCTACCAGCTTTAGCGTAGAGC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GGGCATGGCCTGGCAAGGCACGACCTGGTGCGGCAGGCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TGTAGAGGCCACGATTGCGGTGGACCAGGCAAACCTG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CTCCCCGAGGTAGTAGGCCTCCACGCGCTCAATCAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGGGAGGGCATGAACGCCGTCCTGGCCTGGCTTCAG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GCCTTTATGGCGGCGCTCTCCATGAGAGCCTGGAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CACGGCGCGGACCGCCCAGGACACGCGCATCTGCA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CGGAGGGTGCAGGGCGAGGAGGACGGCCACCTCCCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|224124
LR027520.1|VCU54969.1|329817_330708_+|Hemin-binding-periplasmic-protein-HmuT	unknown	unknown	gnl|CDD|238569
LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein	cas7	cls000038_cas7_CAS-I-B	unknown
LR027520.1|VCU54971.1|330811_331837_+|Hemin-transport-system-permease-protein-HmuU	unknown	unknown	gnl|CDD|223682
LR027520.1|VCU54974.1|332924_333839_+|Putative-ABC-transporter-substrate-binding-lipoprotein-YhfQ	unknown	unknown	gnl|CDD|238566
LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	unknown
LR027520.1|VCU54972.1|331829_332609_+|Hemin-import-ATP-binding-protein-HmuV	unknown	unknown	gnl|CDD|224045
LR027520.1|VCU54968.1|329203_329794_+|hypothetical-protein	unknown	unknown	gnl|CDD|371771
LR027520.1|VCU54963.1|325142_325514_-|hypothetical-protein	unknown	unknown	gnl|CDD|307151
LR027520.1|VCU54966.1|327433_328636_-|hypothetical-protein	unknown	unknown	gnl|CDD|307151
LR027520.1|VCU54967.1|328890_329211_+|Heme-degrading-monooxygenase-HmoB	unknown	unknown	gnl|CDD|225209
LR027520.1|VCU54965.1|325944_326112_-|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54964.1|325565_325868_-|hypothetical-protein	unknown	unknown	gnl|CDD|307151
LR027520.1|VCU54975.1|333835_334882_+|Iron-regulated-protein-A	unknown	unknown	gnl|CDD|271141
LR027520.1|VCU54970.1|330704_330818_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54962.1|324918_325143_-|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	unknown
LR027520.1|VCU54973.1|332598_332913_+|hypothetical-protein	unknown	unknown	unknown
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein	cas6	cd09652_cas6_CAS-I:CAS-III	5e-34	113.1	0.0
LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3	cas3	cd09639_cas3_CAS-I	5.1e-46	152.0	0.0
LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein	cas7	cls000038_cas7_CAS-I-B	1.6e-152	501.6	0.0
LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	3.9e-168	555.6	0.0
LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	1e-141	465.7	0.0
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	2e-42	139.9	2.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.26839e-32
LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.42475e-41
LR027520.1|VCU54969.1|329817_330708_+|Hemin-binding-periplasmic-protein-HmuT	gnl|CDD|238569	cd01149, HutB, Hemin binding protein HutB. These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.49494e-85
LR027520.1|VCU54974.1|332924_333839_+|Putative-ABC-transporter-substrate-binding-lipoprotein-YhfQ	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	7.99608e-54
LR027520.1|VCU54972.1|331829_332609_+|Hemin-import-ATP-binding-protein-HmuV	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	8.13046e-88
LR027520.1|VCU54968.1|329203_329794_+|hypothetical-protein	gnl|CDD|371771	pfam11866, DUF3386, Protein of unknown function (DUF3386). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 220 amino acids in length.	1.73778e-20
LR027520.1|VCU54963.1|325142_325514_-|hypothetical-protein	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	2.55199e-26
LR027520.1|VCU54971.1|330811_331837_+|Hemin-transport-system-permease-protein-HmuU	gnl|CDD|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	1.48972e-78
LR027520.1|VCU54967.1|328890_329211_+|Heme-degrading-monooxygenase-HmoB	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	4.60802e-31
LR027520.1|VCU54964.1|325565_325868_-|hypothetical-protein	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	5.70638e-16
LR027520.1|VCU54975.1|333835_334882_+|Iron-regulated-protein-A	gnl|CDD|271141	cd14658, Imelysin-like_IrpA, Imelysin-like domain in iron-regulated protein A. This family includes putative iron-regulated protein A (IrpA) mainly from Bacteriodes, proteobacteria and cyanobacteria, with domain similar to insulin-cleaving membrane protease (imelysin, ICMP) protein. It has been shown to be essential for growth under iron-deficient conditions in the cyanobacteria Synechococcus sp. The conserved GxHxxE motif is similar to other known imelysin-like proteins that are regulated by iron, such as ICMP, IrpA and EfeO. Imelysin is a membrane protein with the active site outside the cell envelope. The tertiary structure shows a fold consisting of two domains, each of which consists of a bundle of four helices that are similar to each other, implying an ancient gene duplication and fusion event.	5.35054e-52
LR027520.1|VCU54966.1|327433_328636_-|hypothetical-protein	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	1.19603e-90
LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.77582e-39

Protein sequences

>LR027520.1|VCU54965.1|325944_326112_-|hypothetical-protein
MDQDTLQVMLREAVRQTVTEVLQILLDADREAFLRQHGGRKNGYYPASWRPPLAR
>LR027520.1|VCU54964.1|325565_325868_-|hypothetical-protein
MGEVAIALYAAGVSQRKAAEVMSLLLGHRYTHETISAITDQVLEAAEAFQKRPLPEEMAFVYLDGFFLKVLREGLGVERAAVYVALGVTPKGRGRFWAAR
>LR027520.1|VCU54963.1|325142_325514_-|hypothetical-protein
MLKELWERGLRRVLLLVTDGLPGIEEAIRRVYPMAGWQRCVVHMVRSSLGQVRSRDRALLAQDLKGVYMAGSRQEALGALERLREAWGARYPSLVAAWWENSGALLRFYDYPRCSGPIFAALT
>LR027520.1|VCU54962.1|324918_325143_-|hypothetical-protein
MERFIREVRRGTKVRDHKFPKGEAVYKLLYLESERQEGRWAERRLKGFAEVQEVLEGMLRERYAPRTQTLTHKS
>LR027520.1|VCU54961.1|324010_324805_+|hypothetical-protein
MPQAVVLELVGEKPPLYPGRYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRVGPEGATLKGILRLRLTALDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFAYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL
>LR027520.1|VCU54960.1|321557_324011_+|Putative-CRISPR-associated-nuclease/helicase-Cas3
MGEGIGRVFFLKDKVGFQPLSNHQGLVVKLLESWREGDEPLALSPKTKERLLLAARYHDDGKRFTFRIVPDGKGGLTYSFRGHRFRVAQAVQDPYAQALIRGHHDYSTREVVNLAADFLEEGLGHRFPEDLFLLMMADQLEAELAVRLWQGQAGEVRPFVEFDLLPDGEGGFLLDPWPFRVDEVALDFLVYFHPYRGEEAEVVEGWGRALVGALEEGKVPEAFREEKRRVHLRPWAAGARKADDPEAFYARFGLKPTPFQREVFKVAEGDPAHLLLAPTGTGKTEAAAFPALARGERLVFVLPTRSLVDDLEGRFRRYLKILAQEEGRPKALVVDTGHRQARFRFSPDGQEEATKERHLYHADVILTTLDKLLYRYFGYAEGVKSYTFPRRIHDRRTLFVFDEVHLYEATAWVNFRHLIASLYKAGVRFLVMSATMPGTYREELLLEGTLEHPPAKRPSRVLRYMPQGNPMEIIQSHRDKRVLVVLEEVKEAAELYKGLKGEGVFLYHGRLAEGQRRRVFGEVKRRDGAQKPYLLITTPAIEVGVDLDAEVLVTTLCPPENLLQRLGRVNRRGRGQGEAYVVGETYPDYLGSLPEGYLELLKALDGQDLAQGGEERLRQAIRYPKYLDPRAETFFEALQEYVYGLDLTQEPLHRKGFVATRGWTPSVRLRQGEDEVEVPIDRLVGRKEELTPVRVVERLLTDGEKGNRRREEVPLRSGELYGRELVLDYPYPYDAELGFVELPKVFQRLRHPDPQRVQLLYAPEKDAGEAPEGVMDTDQVTGGGRRVLWYLGESAWAEPAKSGEVAEETEEEEEEGD
>LR027520.1|VCU54959.1|320799_321591_+|hypothetical-protein
MYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS
>LR027520.1|VCU54958.1|319916_320798_+|hypothetical-protein
MASGLTPKGEALYHWDIYALLYAPQEVYFGHETQVNVNLIETVSLPDGSERVYLSPTKRRGVERRALLYAPVERNGQHLYLTDLLNCGIPNTCGRENCPVCRVYGALVTERRGNIERTTFIGRLTHGGGVSIPAWQPLEKQRAMHPSDLRRESGEEPQPFRRQYGAPGLLFPVYNHVLAASEREFRAVAYAFLASLPRLGAGNPKGLDLYEDETFGPYLVLDRYKAPLGRRVVLPPTLKDPGEALAEFRRRAEDAPEGGALFQRHRGRAALEALRRLAKAFVEEDLPALASAS
>LR027520.1|VCU54957.1|317890_319915_+|hypothetical-protein
MVNSCHTDYLAQAKKVAADVKAGLATKEALLSFLEAASDPRFSTYLERLDPNLFRFINLVVKGRVSGKPVLHSPQGTVHTLYVSPFPREGQLRVAYEVGLNGFLEYLESKGYAVLEKRETWLKLYEPRRSYLRSLKEGIQKAWEEYLSQILSLESLLNNLGVLISSLKRLGLSLSDSSRAGSGISLPDVPVPNKGVAFFLLAWCLAEEQISESDLGQLPSEKRALVKEAAEKLKGGRGRYLLGKSYAKAIRKRAKELIRCVEDNSFDPWPRCVLSPEVPFLLLRDAGDAQGSICYGCGHALPRSGGSLRAYKISKIVFSKPTVRRQSDYDGTDNKARICDLCAVLSLASPLKLAQGSVLVRVGHLDEGEIARHFVRSAVLGTLHVAAGRYIQLNSPILTRKSKPLAQELGRVVYALQALGQEVNPKVLERFPFYLVEGAQEIPLPPRALWLSHVLQRAFASRPDEGGEVNRPLGEALRYALGDLPWHALYTLARRYGRVADRFSLEDGLMRYASLLEKEVGMKENTDLSQRFRDVAGLTGLLSAWVGYVEGQVGRNSQEAKRAVVKLLDNLERPGDFLYVAAYHLDSTQARLYEAGGAFFYQEAKRLLQEAGARAQEAEEGSGRFLNVSQDDLHRVYAHLAARYPGKAWEGFIYEVRLSLASRFPQYIRMEKEG
>LR027520.1|VCU54956.1|316874_317873_+|hypothetical-protein
MVEWAQAMESRLPDFLRLLRENPRGLPVREIAARLGVRRQSVYRLRDKAQSLGVWVETHGENPEVPPGWMRLEAPLEVTVRLTLEEAEALRAAVERMEPLTPLAKRALERLALRTLAAPGKDRQDPVVYTPLADEYPPGLFERAVRAIRERRTCQVTYKNAKGEVKTYRFDPYALIARDPHLYLVGANHNSRRAGHDPVKDLRLDQILDLRLTRERFRKPRFDVRAYAQHRFRAFAGEGAPVRVRVRFSPEKAGFIRRTRRHPTQVVEDLPDGSVVWQVEVPLSEDLVHFIVGYGPHATVLEPEELRRRVVAWAKGAVEANATLIVFQHRRY
>LR027520.1|VCU54966.1|327433_328636_-|hypothetical-protein
MDQDTLRILLREAVRETVAEVLQTVLELDRTAFLQVHGGRRNGYYPRKLETTFGQVDLKVPRDRESRYYPAFLKPYARRLVDVGEVAVALYAAGVSQRKAAEILSLLLGHRYSHETISALTDQVLEAAGAFRTRPLPEEMAFVYLDGLSLKVFREGEGIVRESVYVALGIAPDGERRVLGFWLLPTESALGWEGVLGELWQRGLRRVLLFVTDGLPGLPEAIRRVYPQAEWQRCVVHGVRWSLSQVRARDRGLLAEDLRRVYGAESREEALGALEEVKAAWGSRYPGVVGLWVQDSGAFLRFYGYPKVLWPYLRSTNLMERFIRELRRGTKVRDHKFPKEEAVYKLLYLESERQAASRSEHLAGRWAERKLKGFSEVKEVLEKMLQERYAPRTQTLTHNS
>LR027520.1|VCU54967.1|328890_329211_+|Heme-degrading-monooxygenase-HmoB
MFVTMNRIPVRPEYAEQFEEAFRQRARLVDRMPGFIRNLVLRPKDPGDPYVVMTLWESEEAFRAWTESPAFKEGHARSGTLPKEAFLGPNRLEAFEVVLDSEGRDG
>LR027520.1|VCU54968.1|329203_329794_+|hypothetical-protein
MVETPPAWVLLKRARERIYTLPPDFPGFRARLGLCLDGVWYVGAVEAEGFAPKVLGLFGEAGAIAEKELASLLGHRRPAPFEEGEGRYPMRLFAEGPLGTGIALEDPFRSRIWVKEGRLALIERHLPEGSFRIHLETWREVGERLLPHRFLLVHRDPRGHLLKVERFRDEYAQVGPYWLPVEREVVVEGEGLGVLA
>LR027520.1|VCU54969.1|329817_330708_+|Hemin-binding-periplasmic-protein-HmuT
MLLGVFGALASAQSYRVVDARGKGVEVRSVERIVSLDGITTEILFALGVGERVVGRDDSSYYPPEAQRLPSVGYQFRLSAEGILSLKPTLVIGREDVRPKEVVEQLERAGVAVVLVPTEPSVEGAKAKIRTVAQAVGRVEQGEALVRALERDLLLLRAFQAQHAAKGKLRALFLYLRGPGTTYVCGEGSTPVGVMALAGLENAAQGIRECKPMTAESVVAARPEVIVVFKKGLESVGGLEGLLKLPGVAQTPAGQKRKVVAMDDLYLGSFGPRAGRAALDLFRAAYLQEGFVEVGP
>LR027520.1|VCU54970.1|330704_330818_+|hypothetical-protein
MKNYLFLRAFFKAALLLLLLGKPVPESLEAAFRGARW
>LR027520.1|VCU54971.1|330811_331837_+|Hemin-transport-system-permease-protein-HmuU
MVGLFPRFRRYRLALLGFSLALPLTLLLGAGLGAYPIPPLAIPGILLRGEGVEYQVLVALRLPRVLGAAVVGGLLALAGAVLQGLFRNPLVDPGLIGVSSGAALGAALFIVLVPGAGPLEVYALPLFAFLGGLLATSLLWRLAQSPWGTQVTILLLSGIALNALVGAGIGLLTFLATEEELRSLTFWTLGGFSALTWRLLLVGVPFAFLAFALLLPLARPLNALALGEREAFHLGIDLERLKRRAVAGAALGVGVAVALAGGVGFLGLVAPHLFRLLAGPDHRYLLPGSALLGGSLAVLADLLARTLAAPAEIPVGVVTALLGGPFFLYLVLRHKREVYRA
>LR027520.1|VCU54972.1|331829_332609_+|Hemin-import-ATP-binding-protein-HmuV
MLKVQNLGYRVGERWLLRGVDLAVGEGEFLAVLGPNGSGKTTLLRLLAGELRPTEGEVFLLGEPLAVYGPQALARQRAVLSQVREMAFPYTAYEVAFLGRLPHLVGRERPLDHRKTLEALERVRALSLKERLFPSLSGGEAMRVEVARLLNQEARLLLLDEPTNHLDPRYALELLCLFRALAYEGKGVVAVLHDLNLAGLFADRVLLLKEGRAVAYGPPQAVLHPGLLEEVYEVAFSVLGQPGGPTFWVPLPREVVRGA
>LR027520.1|VCU54973.1|332598_332913_+|hypothetical-protein
MEPEHAEVVARLSEGRYLARCSCNGGTYHLHWDAATFRLTPEGLTFLAQVLEDLLAQGNDEGAVWLGSVGLRFRKGEGWGLLRLLRQGLLPGKEPPRALLRHLN
>LR027520.1|VCU54974.1|332924_333839_+|Putative-ABC-transporter-substrate-binding-lipoprotein-YhfQ
MQKSLWLVGWVAALALAQAACPGGRVAHDLGEVCLPAPPKRVVTLDWRPLEDLLLLGVRPVAGADLEDFPRWVRLSLPRGSKNLGSRTAPNLELLAALKPDLILGYTGFQGRLYPELSRIAPTALYDYLPPEGQLAAMERHFLLHARLVGKEEEGKKVLEDLKRFLAQSGQSLRDKGLAEKPFLLVQAWAREKVYNVFTRATLASELLERIGLRNTWKGRAEAYGLSRVGPEGLVRLVRENPEVLVFLIAQPENNPFKDPAVGPLLRLTRAQILPLAPTTWTYGGPHSARVLVEEVLRAIGGVK
>LR027520.1|VCU54975.1|333835_334882_+|Iron-regulated-protein-A
MRRIGIGLVLFGVALAQGFKEDLRATVEPLLLGLAGGTEVLAEAAEAYAGGPTTEGLNRLRLLWLAARRPWEELEAFAFGPVGEFDPYLDTWPISPEDLKRTLGSPAADLPPEVRGFHALEYLLFQEPARTPEAARHLARLARDLAEKAAALRRAYLDYLEKTPEEELKEELYAASLELAEELFSEKLKRPESPYAQASAEDYRANAQGLAKALALLPLPGLAWALALDLERAVAALPSPLEGAWDDPKVALALARARDLYAALGKAPVGRAERRALLWLRAFREEYLDEGEVDEGLEALEGLKAALAGTPREEEALKLVEALEAKVRAAAPKEEVEPLVKALEDLLR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR027520_1	1.1|73942|32|LR027520|PILER-CR	73942-73973	32	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	73942-73973	0	1.0
LR027520_1	1.2|74004|32|LR027520|PILER-CR	74004-74035	32	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	74004-74035	0	1.0
LR027520_1	1.3|74066|31|LR027520|PILER-CR	74066-74096	31	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	74066-74096	0	1.0
LR027520_1	1.4|73943|31|LR027520|CRT	73943-73973	31	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	73943-73973	0	1.0
LR027520_1	1.5|74005|31|LR027520|CRT	74005-74035	31	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	74005-74035	0	1.0
LR027520_1	1.6|74067|30|LR027520|CRT	74067-74096	30	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	74067-74096	0	1.0
LR027520_1	1.7|73941|34|LR027520|CRISPRCasFinder	73941-73974	34	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	73941-73974	0	1.0
LR027520_1	1.8|74003|34|LR027520|CRISPRCasFinder	74003-74036	34	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	74003-74036	0	1.0
LR027520_1	1.9|74065|33|LR027520|CRISPRCasFinder	74065-74097	33	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	74065-74097	0	1.0
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	84815-84846	0	1.0
LR027520_2	2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84876-84908	33	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	84876-84908	0	1.0
LR027520_2	2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84938-84970	33	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	41150-41182	0	1.0
LR027520_2	2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84938-84970	33	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	84938-84970	0	1.0
LR027520_2	2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	85000-85031	32	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	41089-41120	0	1.0
LR027520_2	2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	85000-85031	32	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	85000-85031	0	1.0
LR027520_3	3.1|310230|35|LR027520|CRISPRCasFinder	310230-310264	35	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	310230-310264	0	1.0
LR027520_4	4.1|311453|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	311453-311488	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311453-311488	0	1.0
LR027520_4	4.2|311525|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	311525-311560	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311525-311560	0	1.0
LR027520_4	4.3|311597|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	311597-311633	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311597-311633	0	1.0
LR027520_4	4.4|311670|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	311670-311706	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311670-311706	0	1.0
LR027520_4	4.5|311743|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	311743-311778	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311743-311778	0	1.0
LR027520_4	4.6|311815|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	311815-311851	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311815-311851	0	1.0
LR027520_4	4.7|311888|34|LR027520|PILER-CR,CRISPRCasFinder,CRT	311888-311921	34	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311888-311921	0	1.0
LR027520_4	4.8|311958|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	311958-311995	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	311958-311995	0	1.0
LR027520_4	4.9|312032|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	312032-312069	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312032-312069	0	1.0
LR027520_4	4.10|312106|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312106-312141	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312106-312141	0	1.0
LR027520_4	4.11|312178|35|LR027520|PILER-CR,CRISPRCasFinder,CRT	312178-312212	35	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312178-312212	0	1.0
LR027520_4	4.12|312249|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	312249-312286	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312249-312286	0	1.0
LR027520_4	4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312323-312358	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312323-312358	0	1.0
LR027520_4	4.14|312395|34|LR027520|PILER-CR,CRISPRCasFinder,CRT	312395-312428	34	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312395-312428	0	1.0
LR027520_4	4.15|312465|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312465-312500	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312465-312500	0	1.0
LR027520_4	4.16|312537|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	312537-312573	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312537-312573	0	1.0
LR027520_4	4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT	312610-312643	34	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312610-312643	0	1.0
LR027520_4	4.18|312680|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312680-312715	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312680-312715	0	1.0
LR027520_4	4.19|312752|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	312752-312788	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312752-312788	0	1.0
LR027520_4	4.20|312825|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	312825-312861	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312825-312861	0	1.0
LR027520_4	4.21|312898|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312898-312933	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312898-312933	0	1.0
LR027520_4	4.22|312970|35|LR027520|PILER-CR,CRISPRCasFinder,CRT	312970-313004	35	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	312970-313004	0	1.0
LR027520_4	4.23|313041|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	313041-313078	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313041-313078	0	1.0
LR027520_4	4.24|313115|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	313115-313151	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313115-313151	0	1.0
LR027520_4	4.25|313188|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	313188-313223	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313188-313223	0	1.0
LR027520_4	4.26|313260|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	313260-313298	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313260-313298	0	1.0
LR027520_4	4.27|313335|40|LR027520|PILER-CR,CRISPRCasFinder,CRT	313335-313374	40	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313335-313374	0	1.0
LR027520_4	4.28|313411|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	313411-313448	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313411-313448	0	1.0
LR027520_4	4.29|313485|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	313485-313521	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313485-313521	0	1.0
LR027520_4	4.30|313558|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	313558-313594	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313558-313594	0	1.0
LR027520_4	4.31|313631|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	313631-313666	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313631-313666	0	1.0
LR027520_4	4.32|313703|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	313703-313738	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313703-313738	0	1.0
LR027520_4	4.33|313775|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	313775-313810	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313775-313810	0	1.0
LR027520_4	4.34|313847|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	313847-313885	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313847-313885	0	1.0
LR027520_4	4.35|313922|35|LR027520|PILER-CR,CRISPRCasFinder,CRT	313922-313956	35	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313922-313956	0	1.0
LR027520_4	4.36|313993|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	313993-314029	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	313993-314029	0	1.0
LR027520_4	4.37|314066|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	314066-314101	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	314066-314101	0	1.0
LR027520_4	4.38|314138|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	314138-314175	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	314138-314175	0	1.0
LR027520_5	5.1|326362|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	326362-326398	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326362-326398	0	1.0
LR027520_5	5.1|326362|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	326362-326398	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326510-326546	0	1.0
LR027520_5	5.2|326435|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	326435-326473	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326435-326473	0	1.0
LR027520_5	5.2|326435|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	326435-326473	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326583-326621	0	1.0
LR027520_5	5.3|326510|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	326510-326546	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326362-326398	0	1.0
LR027520_5	5.3|326510|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	326510-326546	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326510-326546	0	1.0
LR027520_5	5.4|326583|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	326583-326621	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326435-326473	0	1.0
LR027520_5	5.4|326583|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	326583-326621	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326583-326621	0	1.0
LR027520_5	5.5|326658|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	326658-326695	38	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326658-326695	0	1.0
LR027520_5	5.6|326732|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	326732-326767	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326732-326767	0	1.0
LR027520_5	5.7|326804|39|LR027520|PILER-CR,CRISPRCasFinder,CRT	326804-326842	39	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326804-326842	0	1.0
LR027520_5	5.8|326879|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	326879-326915	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326879-326915	0	1.0
LR027520_5	5.9|326952|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	326952-326987	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	326952-326987	0	1.0
LR027520_5	5.10|327024|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	327024-327059	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	327024-327059	0	1.0
LR027520_5	5.11|327096|35|LR027520|PILER-CR,CRISPRCasFinder,CRT	327096-327130	35	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	327096-327130	0	1.0
LR027520_5	5.12|327167|35|LR027520|PILER-CR,CRISPRCasFinder,CRT	327167-327201	35	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	327167-327201	0	1.0
LR027520_5	5.13|327238|36|LR027520|CRISPRCasFinder,CRT	327238-327273	36	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	327238-327273	0	1.0
LR027520_2	2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84938-84970	33	NC_004462	Thermus thermophilus phage IN93, complete genome	10577-10609	1	0.97
LR027520_2	2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84938-84970	33	AB063393	Thermus thermophilus phage IN93 DNA, complete genome	10577-10609	1	0.97
LR027520_4	4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312323-312358	36	NZ_LR027519	Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence	15560-15595	3	0.917
LR027520_4	4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312323-312358	36	NC_005838	Thermus thermophilus HB27 plasmid pTT27, complete sequence	191001-191036	3	0.917
LR027520_4	4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312323-312358	36	NZ_CP020572	Thermus aquaticus strain YT-1 plasmid p61, complete sequence	46182-46217	3	0.917
LR027520_4	4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT	312323-312358	36	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	52644-52679	3	0.917
LR027520_2	2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	85000-85031	32	MH669004	Streptomyces phage Hank144, complete genome	38257-38288	6	0.812
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_CP014917	Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-2, complete sequence	4805-4836	7	0.781
LR027520_2	2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84876-84908	33	NZ_CP050118	Deinococcus radiodurans strain BNK-50 plasmid pMP1, complete sequence	55375-55407	7	0.788
LR027520_2	2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84876-84908	33	NZ_CP050122	Deinococcus radiodurans strain BND-54 plasmid pMP1, complete sequence	177224-177256	7	0.788
LR027520_2	2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84876-84908	33	NZ_CP031502	Deinococcus radiodurans strain R1 dM1 plasmid pMP1, complete sequence	10431-10463	7	0.788
LR027520_2	2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT	84876-84908	33	NC_000958	Deinococcus radiodurans R1 plasmid MP1, complete sequence	146563-146595	7	0.788
LR027520_2	2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	85000-85031	32	MT711888	Pseudomonas phage Dolphis, complete genome	49112-49143	7	0.781
LR027520_1	1.4|73943|31|LR027520|CRT	73943-73973	31	CP000876	Herpetosiphon aurantiacus DSM 785 plasmid pHAU01, complete sequence	184732-184762	8	0.742
LR027520_4	4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT	312610-312643	34	MH744423	Mycobacterium phage Saguaro, complete genome	47935-47968	8	0.765
LR027520_1	1.1|73942|32|LR027520|PILER-CR	73942-73973	32	CP000876	Herpetosiphon aurantiacus DSM 785 plasmid pHAU01, complete sequence	184732-184763	9	0.719
LR027520_1	1.4|73943|31|LR027520|CRT	73943-73973	31	NZ_CP024587	Roseomonas sp. FDAARGOS_362 plasmid unnamed3, complete sequence	74479-74509	9	0.71
LR027520_1	1.7|73941|34|LR027520|CRISPRCasFinder	73941-73974	34	CP000876	Herpetosiphon aurantiacus DSM 785 plasmid pHAU01, complete sequence	184731-184764	9	0.735
LR027520_2	2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	85000-85031	32	NC_009939	Deinococcus geothermalis DSM 11300 plasmid pDGEO02, complete sequence	163454-163485	9	0.719
LR027520_4	4.20|312825|37|LR027520|PILER-CR,CRISPRCasFinder,CRT	312825-312861	37	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	360248-360284	9	0.757
LR027520_4	4.28|313411|38|LR027520|PILER-CR,CRISPRCasFinder,CRT	313411-313448	38	MN857473	Teseptimavirus S2B, complete genome	28549-28586	9	0.763
LR027520_1	1.1|73942|32|LR027520|PILER-CR	73942-73973	32	NZ_CP024587	Roseomonas sp. FDAARGOS_362 plasmid unnamed3, complete sequence	74478-74509	10	0.688
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_CP034786	Escherichia coli strain ECZP248 plasmid pTB402, complete sequence	132641-132672	10	0.688
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_CP044294	Escherichia coli strain P276M plasmid p276M-CTX-M-55, complete sequence	85310-85341	10	0.688
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_CP053372	Proteus cibarius strain G32 plasmid pG32-177, complete sequence	139427-139458	10	0.688
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	CP042894	Escherichia coli strain CFSAN061772 plasmid pCFSAN061772_01, complete sequence	88662-88693	10	0.688
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_CP048027	Escherichia coli strain GZEC065 plasmid pTET-GZEC065, complete sequence	74338-74369	10	0.688
LR027520_2	2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	84815-84846	32	NZ_CP032890	Escherichia coli strain SCEC020022 plasmid pTetA_020022, complete sequence	76623-76654	10	0.688
LR027520_2	2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT	85000-85031	32	NZ_CP021033	Rhizobium sp. NXC14 plasmid pRspNXC14c, complete sequence	2427-2458	10	0.688
LR027520_4	4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT	312610-312643	34	NZ_CP013748	Pseudarthrobacter sulfonivorans strain Ar51 plasmid unnamed, complete sequence	4924-4957	10	0.706

1. spacer 1.1|73942|32|LR027520|PILER-CR matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccgatgtcggccagggtgagatagagggtgtc	CRISPR spacer
ccgatgtcggccagggtgagatagagggtgtc	Protospacer
********************************

2. spacer 1.2|74004|32|LR027520|PILER-CR matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ctcccgttccctctcactcatctgccagatct	CRISPR spacer
ctcccgttccctctcactcatctgccagatct	Protospacer
********************************

3. spacer 1.3|74066|31|LR027520|PILER-CR matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ggacctgtctgacgctttctccgctgagact	CRISPR spacer
ggacctgtctgacgctttctccgctgagact	Protospacer
*******************************

4. spacer 1.4|73943|31|LR027520|CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cgatgtcggccagggtgagatagagggtgtc	CRISPR spacer
cgatgtcggccagggtgagatagagggtgtc	Protospacer
*******************************

5. spacer 1.5|74005|31|LR027520|CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tcccgttccctctcactcatctgccagatct	CRISPR spacer
tcccgttccctctcactcatctgccagatct	Protospacer
*******************************

6. spacer 1.6|74067|30|LR027520|CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gacctgtctgacgctttctccgctgagact	CRISPR spacer
gacctgtctgacgctttctccgctgagact	Protospacer
******************************

7. spacer 1.7|73941|34|LR027520|CRISPRCasFinder matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gccgatgtcggccagggtgagatagagggtgtcc	CRISPR spacer
gccgatgtcggccagggtgagatagagggtgtcc	Protospacer
**********************************

8. spacer 1.8|74003|34|LR027520|CRISPRCasFinder matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gctcccgttccctctcactcatctgccagatctt	CRISPR spacer
gctcccgttccctctcactcatctgccagatctt	Protospacer
**********************************

9. spacer 1.9|74065|33|LR027520|CRISPRCasFinder matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gggacctgtctgacgctttctccgctgagactc	CRISPR spacer
gggacctgtctgacgctttctccgctgagactc	Protospacer
*********************************

10. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
atgctatccaaaatgccgtcaagcttagcttc	Protospacer
********************************

11. spacer 2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ctcggcctcgtggacgacgtgaaccgtgccaac	CRISPR spacer
ctcggcctcgtggacgacgtgaaccgtgccaac	Protospacer
*********************************

12. spacer 2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 0, identity: 1.0

gccgccctgtggttccgctacggctccgggcgg	CRISPR spacer
gccgccctgtggttccgctacggctccgggcgg	Protospacer
*********************************

13. spacer 2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gccgccctgtggttccgctacggctccgggcgg	CRISPR spacer
gccgccctgtggttccgctacggctccgggcgg	Protospacer
*********************************

14. spacer 2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 0, identity: 1.0

tagagctcctccagggtcttggggcggtccct	CRISPR spacer
tagagctcctccagggtcttggggcggtccct	Protospacer
********************************

15. spacer 2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tagagctcctccagggtcttggggcggtccct	CRISPR spacer
tagagctcctccagggtcttggggcggtccct	Protospacer
********************************

16. spacer 3.1|310230|35|LR027520|CRISPRCasFinder matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tcaccgcgccgcgcctgccatgcctcgccctgccc	CRISPR spacer
tcaccgcgccgcgcctgccatgcctcgccctgccc	Protospacer
***********************************

17. spacer 4.1|311453|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggggcaggaaacccggtgagcacggggagcgt	CRISPR spacer
cttcggggcaggaaacccggtgagcacggggagcgt	Protospacer
************************************

18. spacer 4.2|311525|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tcacctggaggcggaagagggcgttcacagcttcct	CRISPR spacer
tcacctggaggcggaagagggcgttcacagcttcct	Protospacer
************************************

19. spacer 4.3|311597|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ggaagagggccagggggcggaagaagagggcggcaaa	CRISPR spacer
ggaagagggccagggggcggaagaagagggcggcaaa	Protospacer
*************************************

20. spacer 4.4|311670|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cccagaactcccacagggcctccaccctgccctccct	CRISPR spacer
cccagaactcccacagggcctccaccctgccctccct	Protospacer
*************************************

21. spacer 4.5|311743|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tatagcccccgagtggaggccgttctggaagtggac	CRISPR spacer
tatagcccccgagtggaggccgttctggaagtggac	Protospacer
************************************

22. spacer 4.6|311815|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

accccaacgtgctcgccgagaggccggctccccaacc	CRISPR spacer
accccaacgtgctcgccgagaggccggctccccaacc	Protospacer
*************************************

23. spacer 4.7|311888|34|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccagctcgttggtcctctccattgaggggacctc	CRISPR spacer
ccagctcgttggtcctctccattgaggggacctc	Protospacer
**********************************

24. spacer 4.8|311958|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cccggaggagcgccttgacccgcctatgcccccacgcc	CRISPR spacer
cccggaggagcgccttgacccgcctatgcccccacgcc	Protospacer
**************************************

25. spacer 4.9|312032|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tggggggtgcaggggggcgtcagtcccccctgcctgca	CRISPR spacer
tggggggtgcaggggggcgtcagtcccccctgcctgca	Protospacer
**************************************

26. spacer 4.10|312106|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccacctgcatgctcacctccaggccgggtggtaggc	CRISPR spacer
ccacctgcatgctcacctccaggccgggtggtaggc	Protospacer
************************************

27. spacer 4.11|312178|35|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tcttcacgctcacgctcccaacacatctcgcaata	CRISPR spacer
tcttcacgctcacgctcccaacacatctcgcaata	Protospacer
***********************************

28. spacer 4.12|312249|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccaggtagtgctcgccgtccacgggccgggccaggggg	CRISPR spacer
ccaggtagtgctcgccgtccacgggccgggccaggggg	Protospacer
**************************************

29. spacer 4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ttggtggtggcgtcggcggggaactacgggcaggac	CRISPR spacer
ttggtggtggcgtcggcggggaactacgggcaggac	Protospacer
************************************

30. spacer 4.14|312395|34|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tgaaccagattcaccaggggtggtgaaccagatt	CRISPR spacer
tgaaccagattcaccaggggtggtgaaccagatt	Protospacer
**********************************

31. spacer 4.15|312465|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cccccctgcaccgccaccccggcggcgatggagagg	CRISPR spacer
cccccctgcaccgccaccccggcggcgatggagagg	Protospacer
************************************

32. spacer 4.16|312537|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ctcccggagggcgggccaccagcgctcccaacccgcg	CRISPR spacer
ctcccggagggcgggccaccagcgctcccaacccgcg	Protospacer
*************************************

33. spacer 4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccggcgcaggtcctcggggacctccatggcgtca	CRISPR spacer
ccggcgcaggtcctcggggacctccatggcgtca	Protospacer
**********************************

34. spacer 4.18|312680|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

aggcctcagcgtcagggcggggaaccccccgcaagc	CRISPR spacer
aggcctcagcgtcagggcggggaaccccccgcaagc	Protospacer
************************************

35. spacer 4.19|312752|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cttcgtcttgaggcgatgaagacgttggctctcatag	CRISPR spacer
cttcgtcttgaggcgatgaagacgttggctctcatag	Protospacer
*************************************

36. spacer 4.20|312825|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tccgctcgcgggtcacggcctggacggcggtggagga	CRISPR spacer
tccgctcgcgggtcacggcctggacggcggtggagga	Protospacer
*************************************

37. spacer 4.21|312898|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccggggaagctcctccacgggggggtagaggtcggg	CRISPR spacer
ccggggaagctcctccacgggggggtagaggtcggg	Protospacer
************************************

38. spacer 4.22|312970|35|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtgatacgaatgactagacaggcgcaggttcagta	CRISPR spacer
gtgatacgaatgactagacaggcgcaggttcagta	Protospacer
***********************************

39. spacer 4.23|313041|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccggggcagctcctcgtgggcctgcttccaggccagga	CRISPR spacer
ccggggcagctcctcgtgggcctgcttccaggccagga	Protospacer
**************************************

40. spacer 4.24|313115|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

aaaagatggtccaaggacccgttgtccaccacggggt	CRISPR spacer
aaaagatggtccaaggacccgttgtccaccacggggt	Protospacer
*************************************

41. spacer 4.25|313188|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ctccccgagccgggtgccgtcctcgccctttttccg	CRISPR spacer
ctccccgagccgggtgccgtcctcgccctttttccg	Protospacer
************************************

42. spacer 4.26|313260|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtggctcaagctgggctggtccaccaccgccgactac	CRISPR spacer
gtgtggctcaagctgggctggtccaccaccgccgactac	Protospacer
***************************************

43. spacer 4.27|313335|40|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cagaggacgaccccgtggagagggcgcggagattttttgt	CRISPR spacer
cagaggacgaccccgtggagagggcgcggagattttttgt	Protospacer
****************************************

44. spacer 4.28|313411|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gagggagggggctcttccgccgcctcgggcggaaggga	CRISPR spacer
gagggagggggctcttccgccgcctcgggcggaaggga	Protospacer
**************************************

45. spacer 4.29|313485|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtgaacggtgcttagcgttgagctcatccacaaggcc	CRISPR spacer
gtgaacggtgcttagcgttgagctcatccacaaggcc	Protospacer
*************************************

46. spacer 4.30|313558|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ccagggcggtgaagtccaccgcccgctcctccaggac	CRISPR spacer
ccagggcggtgaagtccaccgcccgctcctccaggac	Protospacer
*************************************

47. spacer 4.31|313631|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gccccacgagggcgaggaacagccgcttcacacgct	CRISPR spacer
gccccacgagggcgaggaacagccgcttcacacgct	Protospacer
************************************

48. spacer 4.32|313703|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

atgcgccagaccatagagcagttcatgaagcagtac	CRISPR spacer
atgcgccagaccatagagcagttcatgaagcagtac	Protospacer
************************************

49. spacer 4.33|313775|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

agggcgatggtctacgacgcggaccgccagctcggg	CRISPR spacer
agggcgatggtctacgacgcggaccgccagctcggg	Protospacer
************************************

50. spacer 4.34|313847|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gctcctccgggggtgggactggcaccggggggtagagat	CRISPR spacer
gctcctccgggggtgggactggcaccggggggtagagat	Protospacer
***************************************

51. spacer 4.35|313922|35|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gaagcgctcacggccaagttccagtcccgccgggg	CRISPR spacer
gaagcgctcacggccaagttccagtcccgccgggg	Protospacer
***********************************

52. spacer 4.36|313993|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tgtctaccccctgcaggagggagaggaggctggactt	CRISPR spacer
tgtctaccccctgcaggagggagaggaggctggactt	Protospacer
*************************************

53. spacer 4.37|314066|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gagctttcccccgagggcctcctccgccttcttctc	CRISPR spacer
gagctttcccccgagggcctcctccgccttcttctc	Protospacer
************************************

54. spacer 4.38|314138|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtggcgggtggacctctgaaagggggccaccagggcct	CRISPR spacer
gtggcgggtggacctctgaaagggggccaccagggcct	Protospacer
**************************************

55. spacer 5.1|326362|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tttcacggggtgcgtaggggggtgagggccgcccaaa	CRISPR spacer
tttcacggggtgcgtaggggggtgagggccgcccaaa	Protospacer
*************************************

56. spacer 5.1|326362|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tttcacggggtgcgtaggggggtgagggccgcccaaa	CRISPR spacer
tttcacggggtgcgtaggggggtgagggccgcccaaa	Protospacer
*************************************

57. spacer 5.2|326435|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtggcgatggcggtggccaggccaaagtcatcaatgccg	CRISPR spacer
gtggcgatggcggtggccaggccaaagtcatcaatgccg	Protospacer
***************************************

58. spacer 5.2|326435|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtggcgatggcggtggccaggccaaagtcatcaatgccg	CRISPR spacer
gtggcgatggcggtggccaggccaaagtcatcaatgccg	Protospacer
***************************************

59. spacer 5.3|326510|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tttcacggggtgcgtaggggggtgagggccgcccaaa	CRISPR spacer
tttcacggggtgcgtaggggggtgagggccgcccaaa	Protospacer
*************************************

60. spacer 5.3|326510|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tttcacggggtgcgtaggggggtgagggccgcccaaa	CRISPR spacer
tttcacggggtgcgtaggggggtgagggccgcccaaa	Protospacer
*************************************

61. spacer 5.4|326583|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtggcgatggcggtggccaggccaaagtcatcaatgccg	CRISPR spacer
gtggcgatggcggtggccaggccaaagtcatcaatgccg	Protospacer
***************************************

62. spacer 5.4|326583|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtggcgatggcggtggccaggccaaagtcatcaatgccg	CRISPR spacer
gtggcgatggcggtggccaggccaaagtcatcaatgccg	Protospacer
***************************************

63. spacer 5.5|326658|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

agaagcggctaggggaaatcatcagggcagcgcggctt	CRISPR spacer
agaagcggctaggggaaatcatcagggcagcgcggctt	Protospacer
**************************************

64. spacer 5.6|326732|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cgaggatggccgggtctaccagctttagcgtagagc	CRISPR spacer
cgaggatggccgggtctaccagctttagcgtagagc	Protospacer
************************************

65. spacer 5.7|326804|39|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gggcatggcctggcaaggcacgacctggtgcggcaggcc	CRISPR spacer
gggcatggcctggcaaggcacgacctggtgcggcaggcc	Protospacer
***************************************

66. spacer 5.8|326879|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

tgtagaggccacgattgcggtggaccaggcaaacctg	CRISPR spacer
tgtagaggccacgattgcggtggaccaggcaaacctg	Protospacer
*************************************

67. spacer 5.9|326952|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ctccccgaggtagtaggcctccacgcgctcaatcac	CRISPR spacer
ctccccgaggtagtaggcctccacgcgctcaatcac	Protospacer
************************************

68. spacer 5.10|327024|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cgggagggcatgaacgccgtcctggcctggcttcag	CRISPR spacer
cgggagggcatgaacgccgtcctggcctggcttcag	Protospacer
************************************

69. spacer 5.11|327096|35|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gcctttatggcggcgctctccatgagagcctggac	CRISPR spacer
gcctttatggcggcgctctccatgagagcctggac	Protospacer
***********************************

70. spacer 5.12|327167|35|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cacggcgcggaccgcccaggacacgcgcatctgca	CRISPR spacer
cacggcgcggaccgcccaggacacgcgcatctgca	Protospacer
***********************************

71. spacer 5.13|327238|36|LR027520|CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

cggagggtgcagggcgaggaggacggccacctcccc	CRISPR spacer
cggagggtgcagggcgaggaggacggccacctcccc	Protospacer
************************************

72. spacer 2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_004462 (Thermus thermophilus phage IN93, complete genome) position: , mismatch: 1, identity: 0.97

gccgccctgtggttccgctacggctccgggcgg	CRISPR spacer
gccgccctgtggttccggtacggctccgggcgg	Protospacer
***************** ***************

73. spacer 2.3|84938|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to AB063393 (Thermus thermophilus phage IN93 DNA, complete genome) position: , mismatch: 1, identity: 0.97

gccgccctgtggttccgctacggctccgggcgg	CRISPR spacer
gccgccctgtggttccggtacggctccgggcgg	Protospacer
***************** ***************

74. spacer 4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027519 (Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence) position: , mismatch: 3, identity: 0.917

ttggtggtggcgtcggcggggaactacgggcaggac	CRISPR spacer
ctggtggtggcggcggcggggaactacgggcgggac	Protospacer
.*********** ******************.****

75. spacer 4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_005838 (Thermus thermophilus HB27 plasmid pTT27, complete sequence) position: , mismatch: 3, identity: 0.917

ttggtggtggcgtcggcggggaactacgggcaggac	CRISPR spacer
ctggtggtggcggcggcggggaactacgggcgggac	Protospacer
.*********** ******************.****

76. spacer 4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020572 (Thermus aquaticus strain YT-1 plasmid p61, complete sequence) position: , mismatch: 3, identity: 0.917

ttggtggtggcgtcggcggggaactacgggcaggac	CRISPR spacer
ctggtggtggcggcggcggggaactacgggcgggac	Protospacer
.*********** ******************.****

77. spacer 4.13|312323|36|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 3, identity: 0.917

ttggtggtggcgtcggcggggaactacgggcaggac	CRISPR spacer
ctggtggtggcggcggcggggaactacgggcgggac	Protospacer
.*********** ******************.****

78. spacer 2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to MH669004 (Streptomyces phage Hank144, complete genome) position: , mismatch: 6, identity: 0.812

tagagct-cctccagggtcttggggcggtccct	CRISPR spacer
-agggctgcctccagggccttgcggcggtcctc	Protospacer
 **.*** *********.**** ********..

79. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014917 (Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-2, complete sequence) position: , mismatch: 7, identity: 0.781

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
aagctttcccaaatgccgtcaagctgatgttt	Protospacer
* *** *** *************** *  **.

80. spacer 2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050118 (Deinococcus radiodurans strain BNK-50 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.788

ctcggcctcgtggacgacgtgaaccgtgccaac	CRISPR spacer
atccagcaggtggccgacgtgaaccgtgccaac	Protospacer
 ** . *  **** *******************

81. spacer 2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050122 (Deinococcus radiodurans strain BND-54 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.788

ctcggcctcgtggacgacgtgaaccgtgccaac	CRISPR spacer
atccagcaggtggccgacgtgaaccgtgccaac	Protospacer
 ** . *  **** *******************

82. spacer 2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031502 (Deinococcus radiodurans strain R1 dM1 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.788

ctcggcctcgtggacgacgtgaaccgtgccaac	CRISPR spacer
atccagcaggtggccgacgtgaaccgtgccaac	Protospacer
 ** . *  **** *******************

83. spacer 2.2|84876|33|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_000958 (Deinococcus radiodurans R1 plasmid MP1, complete sequence) position: , mismatch: 7, identity: 0.788

ctcggcctcgtggacgacgtgaaccgtgccaac	CRISPR spacer
atccagcaggtggccgacgtgaaccgtgccaac	Protospacer
 ** . *  **** *******************

84. spacer 2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to MT711888 (Pseudomonas phage Dolphis, complete genome) position: , mismatch: 7, identity: 0.781

tagagctcctccagggtcttggggcggtccct----	CRISPR spacer
tggagctcttccagggtcttggcg----ccctggac	Protospacer
*.******.************* *    ****    

85. spacer 1.4|73943|31|LR027520|CRT matches to CP000876 (Herpetosiphon aurantiacus DSM 785 plasmid pHAU01, complete sequence) position: , mismatch: 8, identity: 0.742

cgatgtcggccagggtgagatagagggtgtc	CRISPR spacer
tggttgttgcctgggtcagatagagggtgtc	Protospacer
.*.*  . *** **** **************

86. spacer 4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to MH744423 (Mycobacterium phage Saguaro, complete genome) position: , mismatch: 8, identity: 0.765

ccggcgca-ggtcctcggggacctccatggcgtca	CRISPR spacer
-cagctcgccgtcctcggtgacctccttggcgtcc	Protospacer
 *.** *.  ******** ******* ******* 

87. spacer 1.1|73942|32|LR027520|PILER-CR matches to CP000876 (Herpetosiphon aurantiacus DSM 785 plasmid pHAU01, complete sequence) position: , mismatch: 9, identity: 0.719

ccgatgtcggccagggtgagatagagggtgtc	CRISPR spacer
atggttgttgcctgggtcagatagagggtgtc	Protospacer
 .*.*  . *** **** **************

88. spacer 1.4|73943|31|LR027520|CRT matches to NZ_CP024587 (Roseomonas sp. FDAARGOS_362 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.71

cgatgtcggccagggtgagatagagggtgtc	CRISPR spacer
tgatgtcggccagggtgtgatcgacctgcac	Protospacer
.**************** *** **      *

89. spacer 1.7|73941|34|LR027520|CRISPRCasFinder matches to CP000876 (Herpetosiphon aurantiacus DSM 785 plasmid pHAU01, complete sequence) position: , mismatch: 9, identity: 0.735

gccgatgtcggccagggtgagatagagggtgtcc	CRISPR spacer
gatggttgttgcctgggtcagatagagggtgtcc	Protospacer
* .*.*  . *** **** ***************

90. spacer 2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NC_009939 (Deinococcus geothermalis DSM 11300 plasmid pDGEO02, complete sequence) position: , mismatch: 9, identity: 0.719

tagagctcctccagggtcttggggcggtccct	CRISPR spacer
tggcgctcctccagggtggtggggcggggatg	Protospacer
*.* *************  ********   . 

91. spacer 4.20|312825|37|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.757

tccgctcgcgggtcacggcctggacggcggtggagga	CRISPR spacer
tgcgctcgcgggtcaccgcctggaccgcgagcgcgac	Protospacer
* ************** ******** ***.  * *. 

92. spacer 4.28|313411|38|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to MN857473 (Teseptimavirus S2B, complete genome) position: , mismatch: 9, identity: 0.763

gagggagggggctcttccgccgcctcgggcggaaggga	CRISPR spacer
tgggcatcccgctgttccgccgcctcggccggaaggga	Protospacer
 .** *    *** ************** *********

93. spacer 1.1|73942|32|LR027520|PILER-CR matches to NZ_CP024587 (Roseomonas sp. FDAARGOS_362 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

ccgatgtcggccagggtgagatagagggtgtc	CRISPR spacer
atgatgtcggccagggtgtgatcgacctgcac	Protospacer
 .**************** *** **      *

94. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034786 (Escherichia coli strain ECZP248 plasmid pTB402, complete sequence) position: , mismatch: 10, identity: 0.688

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
ccagaatccaaaaggccgtcaagctaagagta	Protospacer
 ..  ******** *********** **  * 

95. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044294 (Escherichia coli strain P276M plasmid p276M-CTX-M-55, complete sequence) position: , mismatch: 10, identity: 0.688

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
ccagaatccaaaaggccgtcaagctaagagta	Protospacer
 ..  ******** *********** **  * 

96. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053372 (Proteus cibarius strain G32 plasmid pG32-177, complete sequence) position: , mismatch: 10, identity: 0.688

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
ccagaatccaaaaggccgtcaagctaagagta	Protospacer
 ..  ******** *********** **  * 

97. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to CP042894 (Escherichia coli strain CFSAN061772 plasmid pCFSAN061772_01, complete sequence) position: , mismatch: 10, identity: 0.688

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
ccagaatccaaaaggccgtcaagctaagagta	Protospacer
 ..  ******** *********** **  * 

98. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048027 (Escherichia coli strain GZEC065 plasmid pTET-GZEC065, complete sequence) position: , mismatch: 10, identity: 0.688

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
ccagaatccaaaaggccgtcaagctaagagta	Protospacer
 ..  ******** *********** **  * 

99. spacer 2.1|84815|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032890 (Escherichia coli strain SCEC020022 plasmid pTetA_020022, complete sequence) position: , mismatch: 10, identity: 0.688

atgctatccaaaatgccgtcaagcttagcttc	CRISPR spacer
ccagaatccaaaaggccgtcaagctaagagta	Protospacer
 ..  ******** *********** **  * 

100. spacer 2.4|85000|32|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021033 (Rhizobium sp. NXC14 plasmid pRspNXC14c, complete sequence) position: , mismatch: 10, identity: 0.688

tagagctcctccagggtcttggggcggtccct	CRISPR spacer
gcctgctcctccaggttcttggcgcggccatc	Protospacer
    *********** ****** ****.* ..

101. spacer 4.17|312610|34|LR027520|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013748 (Pseudarthrobacter sulfonivorans strain Ar51 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

ccggcgcaggtcctcggggacctccatggcgtca	CRISPR spacer
ctcgaagtcctcctcggggaccaccatggcctca	Protospacer
*. * .    ************ ******* ***