CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134081	Escherichia coli strain NCTC9033 genome assembly, chromosome: 1	5 crisprs	csa3,PD-DExK,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,cas14j,c2c9_V-U4,DEDDh,RT,DinG	0	14	18	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134081_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134081_1

1208042-1208741

Unclear

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCTAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCTAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCNAGCGGGGATAAACCG	CRT

11 spacers

The CRISPR arrays of LR134081_1

>merge|LR134081|1|1208042-1208741|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCTAGCGGGGATAAACCGGCTGGATACCGATCAATTCAATATCGTTTACGAGTTCCCCGCGCTAGCGGGGATAAACCGGAATACCGATTCATAACGGCGGAAATGTGGATGAGTTCCCCGCGCTAGCGGGGATAAACCGACGAAAAACAGGCTGCAAGTCTCGCTGACCAAGAGTTCCCCGCGCTAGCGGGGATAAACCGCCGGTTAATTTGTTGTACCCGTCGCGCGGTGGGAGTTCCCCGCGCTAGCGGGGATAAACCGATCGCCTCAGCATTTTTTTTTACGCTCAGGGTGGAGTTCCCCGCGCTAGCGGGGATAAACCGGTTAATGATGTCAGTGGCGGTTTTCGTATCGCGAGTTCCCCGCGCTAGCGGGGATAAACCGAGTGAGGCAATCAAATGACCCGCCCGCAATTAGAGTTCCCCGCGCCAGCGGGGATAAACCGTAAATCCCTCGCGCATCGAGTCAAATGTCGGAGAGTTCCCCGCGCCAGCGGGGATAAACCGGTCGCTGGAACGGGGCGAATAAAGAGGGGCTCGAGTTCCCCGCGCCAGCGGGGATAAACCGACAGCTCTTTCCCGTCGTTATCCAGTTGGTAAGAGTTCCCCGCGCCAGCGGGGATAAACCGTTTGCTGGAACCCAAAACTCAGCGCACAGGTTGTGTTCCCCGCGCCAGCGGGGATAAACCA

>LR134081|1|1|1208042-1208680|PILER-CR
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GCTGGATACCGATCAATTCAATATCGTTTAC
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GAATACCGATTCATAACGGCGGAAATGTGGAT
GAGTTCCCCGCGCTAGCGGGGATAAACCG	ACGAAAAACAGGCTGCAAGTCTCGCTGACCAA
GAGTTCCCCGCGCTAGCGGGGATAAACCG	CCGGTTAATTTGTTGTACCCGTCGCGCGGTGG
GAGTTCCCCGCGCTAGCGGGGATAAACCG	ATCGCCTCAGCATTTTTTTTTACGCTCAGGGTG
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GTTAATGATGTCAGTGGCGGTTTTCGTATCGC
GAGTTCCCCGCGCTAGCGGGGATAAACCG	AGTGAGGCAATCAAATGACCCGCCCGCAATTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TAAATCCCTCGCGCATCGAGTCAAATGTCGGA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GTCGCTGGAACGGGGCGAATAAAGAGGGGCTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACAGCTCTTTCCCGTCGTTATCCAGTTGGTAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG

>LR134081|1|1|1208042-1208741|CRISPRCasFinder
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GCTGGATACCGATCAATTCAATATCGTTTAC
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GAATACCGATTCATAACGGCGGAAATGTGGAT
GAGTTCCCCGCGCTAGCGGGGATAAACCG	ACGAAAAACAGGCTGCAAGTCTCGCTGACCAA
GAGTTCCCCGCGCTAGCGGGGATAAACCG	CCGGTTAATTTGTTGTACCCGTCGCGCGGTGG
GAGTTCCCCGCGCTAGCGGGGATAAACCG	ATCGCCTCAGCATTTTTTTTTACGCTCAGGGTG
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GTTAATGATGTCAGTGGCGGTTTTCGTATCGC
GAGTTCCCCGCGCTAGCGGGGATAAACCG	AGTGAGGCAATCAAATGACCCGCCCGCAATTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TAAATCCCTCGCGCATCGAGTCAAATGTCGGA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GTCGCTGGAACGGGGCGAATAAAGAGGGGCTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACAGCTCTTTCCCGTCGTTATCCAGTTGGTAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGCTGGAACCCAAAACTCAGCGCACAGGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCA

>LR134081|1|1|1208042-1208741|CRT
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GCTGGATACCGATCAATTCAATATCGTTTAC
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GAATACCGATTCATAACGGCGGAAATGTGGAT
GAGTTCCCCGCGCTAGCGGGGATAAACCG	ACGAAAAACAGGCTGCAAGTCTCGCTGACCAA
GAGTTCCCCGCGCTAGCGGGGATAAACCG	CCGGTTAATTTGTTGTACCCGTCGCGCGGTGG
GAGTTCCCCGCGCTAGCGGGGATAAACCG	ATCGCCTCAGCATTTTTTTTTACGCTCAGGGTG
GAGTTCCCCGCGCTAGCGGGGATAAACCG	GTTAATGATGTCAGTGGCGGTTTTCGTATCGC
GAGTTCCCCGCGCTAGCGGGGATAAACCG	AGTGAGGCAATCAAATGACCCGCCCGCAATTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TAAATCCCTCGCGCATCGAGTCAAATGTCGGA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GTCGCTGGAACGGGGCGAATAAAGAGGGGCTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACAGCTCTTTCCCGTCGTTATCCAGTTGGTAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGCTGGAACCCAAAACTCAGCGCACAGGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
LR134081.1\|VDY99374.1\|1206256_1206859_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
LR134081.1\|VDY99368.1\|1203644_1204190_-\|putative-glycine-rich-transmembrane-protein	unknown	unknown	gnl\|CDD\|224429
LR134081.1\|VDY99364.1\|1200193_1201831_+\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
LR134081.1\|VDY99392.1\|1216973_1217468_+\|electron-transfer-flavoprotein-subunit-YgcQ	unknown	unknown	gnl\|CDD\|224936
LR134081.1\|VDY99391.1\|1216197_1216977_+\|electron-transfer-flavoprotein-subunit-YgcR	unknown	unknown	gnl\|CDD\|224997
LR134081.1\|VDY99394.1\|1217482_1217833_+\|electron-transfer-flavoprotein-subunit-YgcQ	unknown	unknown	gnl\|CDD\|224936
LR134081.1\|VDY99362.1\|1199174_1199966_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
LR134081.1\|VDY99358.1\|1198519_1198768_+\|antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
LR134081.1\|VDY99360.1\|1198767_1199103_+\|toxin-ChpA	unknown	unknown	gnl\|CDD\|182138
LR134081.1\|VDY99366.1\|1201918_1203217_+\|enolase	unknown	unknown	gnl\|CDD\|234617
LR134081.1\|VDY99384.1\|1213173_1213263_+\|deoxygluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|180761
LR134081.1\|VDY99370.1\|1204186_1205335_-\|putative-glycine-rich-transmembrane-protein	unknown	unknown	gnl\|CDD\|224429
LR134081.1\|VDY99372.1\|1205349_1206243_-\|putative-glycine-rich-transmembrane-protein	unknown	unknown	gnl\|CDD\|224429
LR134081.1\|VDY99382.1\|1212403_1213174_+\|putative-short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|187605
LR134081.1\|VDY99387.1\|1213544_1214789_+\|putative-FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
LR134081.1\|VDY99378.1\|1209378_1210857_-\|putative-sugar-kinase	unknown	unknown	gnl\|CDD\|212662
LR134081.1\|VDY99385.1\|1213332_1213560_+\|putative-FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
LR134081.1\|VDY99389.1\|1214810_1216220_+\|major-facilitator-superfamily-protein	unknown	unknown	gnl\|CDD\|340929
LR134081.1\|VDY99376.1\|1207031_1207703_+\|7-carboxy-7-deazaguanine-synthase;-queosine-biosynthesis	unknown	unknown	gnl\|CDD\|275126
LR134081.1\|VDY99380.1\|1210883_1212161_-\|major-facilitator-superfamily-protein	unknown	unknown	gnl\|CDD\|349949

Protein	Function_ID	Function_description	E-value
LR134081.1\|VDY99374.1\|1206256_1206859_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	1.21919e-77
LR134081.1\|VDY99368.1\|1203644_1204190_-\|putative-glycine-rich-transmembrane-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.13559e-79
LR134081.1\|VDY99364.1\|1200193_1201831_+\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
LR134081.1\|VDY99392.1\|1216973_1217468_+\|electron-transfer-flavoprotein-subunit-YgcQ	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	3.84387e-36
LR134081.1\|VDY99391.1\|1216197_1216977_+\|electron-transfer-flavoprotein-subunit-YgcR	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.05317e-63
LR134081.1\|VDY99394.1\|1217482_1217833_+\|electron-transfer-flavoprotein-subunit-YgcQ	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	1.70395e-37
LR134081.1\|VDY99362.1\|1199174_1199966_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.29417e-158
LR134081.1\|VDY99358.1\|1198519_1198768_+\|antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	1.48592e-47
LR134081.1\|VDY99360.1\|1198767_1199103_+\|toxin-ChpA	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	6.85168e-74
LR134081.1\|VDY99366.1\|1201918_1203217_+\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
LR134081.1\|VDY99384.1\|1213173_1213263_+\|deoxygluconate-dehydrogenase	gnl\|CDD\|180761	PRK06935, PRK06935, 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD.	1.33398e-13
LR134081.1\|VDY99370.1\|1204186_1205335_-\|putative-glycine-rich-transmembrane-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	5.87361e-63
LR134081.1\|VDY99372.1\|1205349_1206243_-\|putative-glycine-rich-transmembrane-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	9.948e-91
LR134081.1\|VDY99382.1\|1212403_1213174_+\|putative-short-chain-dehydrogenase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.48851e-104
LR134081.1\|VDY99387.1\|1213544_1214789_+\|putative-FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.78969e-69
LR134081.1\|VDY99378.1\|1209378_1210857_-\|putative-sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	2.17132e-108
LR134081.1\|VDY99385.1\|1213332_1213560_+\|putative-FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	0.00174188
LR134081.1\|VDY99389.1\|1214810_1216220_+\|major-facilitator-superfamily-protein	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.36018e-51
LR134081.1\|VDY99376.1\|1207031_1207703_+\|7-carboxy-7-deazaguanine-synthase;-queosine-biosynthesis	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
LR134081.1\|VDY99380.1\|1210883_1212161_-\|major-facilitator-superfamily-protein	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	2.8075e-29

>LR134081.1|VDY99376.1|1207031_1207703_+|7-carboxy-7-deazaguanine-synthase;-queosine-biosynthesis
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>LR134081.1|VDY99374.1|1206256_1206859_-|LemA-family-protein
MLRIFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSSHERDVLEAVTLARSQANRASSDLQQTPGDEQKLQAWQQAQAQVTRTLGQLTIISERYPELKSQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNANAH
>LR134081.1|VDY99372.1|1205349_1206243_-|putative-glycine-rich-transmembrane-protein
MRNFIFLMAFFCSSVFATQIPVPESPKYVNDLTGTLTNSEVNTLTNQIKALTQKSHAQLVVLVVETTGDETIEQYATRVFDSWKPGDKDRDDGVLLLVAWQDHTVRIEIGYGLEGIITDAQSRKIIRNSIIPAFKKGDLAGGLQKGISDIESRLTGNNLATITPTDHPLPFSGWWALLVWAIVLTFISARGYIKTLGVICFAAIVLAFVLPIAGFSGSWGVLATLLCFATPFLAVAIAFTPFGKKVRDLMRDVNQPSRHTRSNSSSHYSSSSSSSFNNDNFSGGGGSSGGGGASGRW
>LR134081.1|VDY99370.1|1204186_1205335_-|putative-glycine-rich-transmembrane-protein
MRIFLLLLMLCGFQVFAEQWPSVTDLTGTLTTEEQTALTQQLQTLEQQNHFQVAVLVTPTTGGKNIKLAASQRYGVYHWKPVGEKRYGEGILILVVWPEGLASMKIGHGLEQMLPPEQAAQIVRYHMQPEFEKNNLFAGLTGGIESIAQFTHIKANISPLDALANHLFANPQRSLPCLAWTLLMIVAIVVLWRFASRPRRGIWMISMITPMVWFFSFQDDVIIRRVSVVCFSLLLATTCKQRLAVVFNMCRVFPMMLTPKNKNAKVKKQKKTPQVRESGRNSLFVVMLIIIVGWCLVFASNKDIAFISTIIGLIDHFIGPITIAGIVLLIIVAKFTGNLKLGSGEKSNRKTGNRNAHSRSSSRNSFRGGGGSSGGGGSSGRW
>LR134081.1|VDY99368.1|1203644_1204190_-|putative-glycine-rich-transmembrane-protein
MIVMRLIFILFTLWCLPGLAQQIAVPELRQQVTDITGTLSTSEQQSLTQQLQDITHKTRAQVAVLVVPSTGDDSIEQYATRVFDSWKLGDKQRNDGILLLVAWEDHAVRIEVGYGLEGVVTDLQAAKIIRDILIPAFKSDDLMGGLTLASENIGALLLNGELPEDRGIITVSIPLFHYRLL
>LR134081.1|VDY99366.1|1201918_1203217_+|enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>LR134081.1|VDY99364.1|1200193_1201831_+|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>LR134081.1|VDY99362.1|1199174_1199966_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFSSIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADGSAGNSREVLARWEEIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>LR134081.1|VDY99360.1|1198767_1199103_+|toxin-ChpA
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRAKGATKKGTVAPEELQLIKAKINVLIG
>LR134081.1|VDY99358.1|1198519_1198768_+|antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHDNIDWGEPKDKEVW
>LR134081.1|VDY99378.1|1209378_1210857_-|putative-sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNISNYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>LR134081.1|VDY99380.1|1210883_1212161_-|major-facilitator-superfamily-protein
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAIASSK
>LR134081.1|VDY99382.1|1212403_1213174_+|putative-short-chain-dehydrogenase
MRKVTSLSRGKLPFFFFCLTEIGANYVNRISQCVLNGFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPKPISAFLIIFRQTVGAILKI
>LR134081.1|VDY99384.1|1213173_1213263_+|deoxygluconate-dehydrogenase
MGAAVFLASQASNYVNGHLLVVDGGYLVR
>LR134081.1|VDY99385.1|1213332_1213560_+|putative-FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLEFYECAQN
>LR134081.1|VDY99387.1|1213544_1214789_+|putative-FAD-binding-oxidoreductase
MRTKLTVCRVPVLPATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>LR134081.1|VDY99389.1|1214810_1216220_+|major-facilitator-superfamily-protein
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>LR134081.1|VDY99391.1|1216197_1216977_+|electron-transfer-flavoprotein-subunit-YgcR
MNILLAFKAEPDAGMLAEKEWQAAAQGNSGPDVSLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFASEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAELPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQNYLRQRMQP
>LR134081.1|VDY99392.1|1216973_1217468_+|electron-transfer-flavoprotein-subunit-YgcQ
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLEIPIVSVRKSHWGNALTATLQTEKRPLCLSLARQAGADKNATLPSGIQQLNIVPGALPDWLVSIENLKNVSRDH
>LR134081.1|VDY99394.1|1217482_1217833_+|electron-transfer-flavoprotein-subunit-YgcQ
MLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ

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Crispr_ID: LR134081_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134081_2

1234440-1235077

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACC	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

10 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of LR134081_2

>merge|LR134081|2|1234440-1235077|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGTCAAATCGGTTACCTTAACCTGTTGAATGTGGTGTTCCCCGCGCCAGCGGGGATAAACCGAACGGCTACGGCACCGAGGTGACAAACCAGATGTGTTCCCCGCGCCAGCGGGATAAACCGCCGTTGCGCTGGCATCGGGTGTACCTGTTGTGGTGTTCCCCGCGCCAGCGGGGATAAACCGGGCTTACACGCCACCATGGCATCAAGAACGATGTGTTCCCCGCGCCAGCGGGGATAAACCGATTACGACTTCCGCACGCACCCACCGTTTGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGTTGGGCTAGGAGGAAGAGCATCATTAACATGGGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGTTTCTGGCGGGGGTAGGGAACGCCCAGAAGTGTTCCCCGCGCCAGCGGGGATAAACCTGAGGCGGCTAAACCGTCGCGCACACGAGCGACGTGTTCCCCGCGCCAGCGGGGATAAACCGCGTACTGCTTACTCCGTCATCGATGTATGAGTGTGTTCCCCGCGCCAGCGGGGATAAACCGTACGTGTCGCCGTTACAGATTTCAGTCTGTTAGTGTTCTCCGCGCCAGCGGGGATAAACCG

>LR134081|2|2|1234440-1235076|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGTCAAATCGGTTACCTTAACCTGTTGAATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAACGGCTACGGCACCGAGGTGACAAACCAGAT
GTGTTCCCCGCGCCAGCGGGATAAACCG	CCGTTGCGCTGGCATCGGGTGTACCTGTTGTGGTGTTCCC
CGCGCCAGCGGGGATAAACCGGGCTTAC	ACGCCACCATGGCATCAAGAACGATGTGTTCCC
CGCGCCAGCGGGGATAAACCGATTACGA	CTTCCGCACGCACCCACCGTTTGTAGTGTTCCC
CGCGCCAGCGGGGATAAACCGTTGGGCT	AGGAGGAAGAGCATCATTAACATGGGTGTTCCC
CGCGCCAGCGGGGATAAACCGGCGTTTC	TGGCGGGGGTAGGGAACGCCCAGAAGTGTTCCC
CGCGCCAGCGGGGATAAACCTGAGGCGG	CTAAACCGTCGCGCACACGAGCGACGTGTTCCC
CGCGCCAGCGGGGATAAACCGCGTACTG	CTTACTCCGTCATCGATGTATGAGTGTGTTCCC
CGCGCCAGCGGGGATAAACCGTACGTGT	CGCCGTTACAGATTTCAGTCTGTTAGTGTTCTC
CGCGCCAGCGGGGATAAACC

>LR134081|2|2|1234440-1235077|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCAAATCGGTTACCTTAACCTGTTGAATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AACGGCTACGGCACCGAGGTGACAAACCAGAT
GTGTTCCCCGCGCCAGCGGGATAAACCGC	CGTTGCGCTGGCATCGGGTGTACCTGTTGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGCTTACACGCCACCATGGCATCAAGAACGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTACGACTTCCGCACGCACCCACCGTTTGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGGGCTAGGAGGAAGAGCATCATTAACATGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGTTTCTGGCGGGGGTAGGGAACGCCCAGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCT	GAGGCGGCTAAACCGTCGCGCACACGAGCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTACTGCTTACTCCGTCATCGATGTATGAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGTGTCGCCGTTACAGATTTCAGTCTGTTA
GTGTTCTCCGCGCCAGCGGGGATAAACCG

>LR134081|2|2|1234440-1235077|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCAAATCGGTTACCTTAACCTGTTGAATGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AACGGCTACGGCACCGAGGTGACAAACCAGAT
GTGTTCCCCGCGCCAGCGGGATAAACCGC	CGTTGCGCTGGCATCGGGTGTACCTGTTGTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGCTTACACGCCACCATGGCATCAAGAACGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTACGACTTCCGCACGCACCCACCGTTTGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGGGCTAGGAGGAAGAGCATCATTAACATGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGTTTCTGGCGGGGGTAGGGAACGCCCAGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCT	GAGGCGGCTAAACCGTCGCGCACACGAGCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTACTGCTTACTCCGTCATCGATGTATGAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGTGTCGCCGTTACAGATTTCAGTCTGTTA
GTGTTCTCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
LR134081.1\|VDY99426.1\|1233129_1234053_+\|CRISPR-associated-protein	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
LR134081.1\|VDY99420.1\|1230687_1231743_+\|CRISPR-associated-protein	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
LR134081.1\|VDY99433.1\|1236446_1237355_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235375
LR134081.1\|VDY99447.1\|1241471_1242521_+\|tRNA-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|234884
LR134081.1\|VDY99416.1\|1229810_1230140_+\|CRISPR-associated-protein	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|187800
LR134081.1\|VDY99449.1\|1242501_1243263_+\|stationary-phase-survival-protein-SurE	unknown	unknown	gnl\|CDD\|234732
LR134081.1\|VDY99430.1\|1235274_1236195_-\|alkaline-phosphatase-isozyme-conversion-protein	unknown	unknown	gnl\|CDD\|182299
LR134081.1\|VDY99414.1\|1228578_1229793_+\|CRISPR-associated-protein	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
LR134081.1\|VDY99445.1\|1240995_1241475_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
LR134081.1\|VDY99418.1\|1230136_1230673_+\|CRISPR-associated-protein-Cse2	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
LR134081.1\|VDY99412.1\|1225781_1228481_+\|CRISPR-associated-helicase-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
LR134081.1\|VDY99428.1\|1234049_1234343_+\|CRISPR-associated-protein	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
LR134081.1\|VDY99439.1\|1239438_1239762_+\|putative-cytochrome-oxidase-subunit	unknown	unknown	gnl\|CDD\|371891
LR134081.1\|VDY99424.1\|1232482_1233133_+\|CRISPR-associated-protein	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
LR134081.1\|VDY99443.1\|1240285_1240996_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
LR134081.1\|VDY99410.1\|1224438_1225191_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
LR134081.1\|VDY99422.1\|1231753_1232266_+\|CRISPR-associated-protein	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187886
LR134081.1\|VDY99441.1\|1239955_1240267_+\|cell-division-protein	unknown	unknown	gnl\|CDD\|179156
LR134081.1\|VDY99435.1\|1237356_1238784_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235349
LR134081.1\|VDY99437.1\|1238783_1239389_+\|adenosine-5-phosphosulfate-kinase	unknown	unknown	gnl\|CDD\|179661

Protein	Function_ID	Function_description	E-value
LR134081.1\|VDY99426.1\|1233129_1234053_+\|CRISPR-associated-protein	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.20828e-155
LR134081.1\|VDY99420.1\|1230687_1231743_+\|CRISPR-associated-protein	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	5.01992e-155
LR134081.1\|VDY99433.1\|1236446_1237355_+\|sulfate-adenylyltransferase	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
LR134081.1\|VDY99447.1\|1241471_1242521_+\|tRNA-pseudouridine-synthase-D	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
LR134081.1\|VDY99416.1\|1229810_1230140_+\|CRISPR-associated-protein	gnl\|CDD\|187800	cd09669, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	1.88808e-27
LR134081.1\|VDY99449.1\|1242501_1243263_+\|stationary-phase-survival-protein-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	4.8611e-151
LR134081.1\|VDY99430.1\|1235274_1236195_-\|alkaline-phosphatase-isozyme-conversion-protein	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
LR134081.1\|VDY99414.1\|1228578_1229793_+\|CRISPR-associated-protein	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	6.20101e-152
LR134081.1\|VDY99445.1\|1240995_1241475_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
LR134081.1\|VDY99418.1\|1230136_1230673_+\|CRISPR-associated-protein-Cse2	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	8.02591e-28
LR134081.1\|VDY99412.1\|1225781_1228481_+\|CRISPR-associated-helicase-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.97874e-179
LR134081.1\|VDY99428.1\|1234049_1234343_+\|CRISPR-associated-protein	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
LR134081.1\|VDY99439.1\|1239438_1239762_+\|putative-cytochrome-oxidase-subunit	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
LR134081.1\|VDY99424.1\|1232482_1233133_+\|CRISPR-associated-protein	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	8.7399e-91
LR134081.1\|VDY99443.1\|1240285_1240996_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.58139e-121
LR134081.1\|VDY99410.1\|1224438_1225191_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	2.75122e-131
LR134081.1\|VDY99422.1\|1231753_1232266_+\|CRISPR-associated-protein	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.96488e-34
LR134081.1\|VDY99441.1\|1239955_1240267_+\|cell-division-protein	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
LR134081.1\|VDY99435.1\|1237356_1238784_+\|sulfate-adenylyltransferase	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
LR134081.1\|VDY99437.1\|1238783_1239389_+\|adenosine-5-phosphosulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	5.3035e-147

>LR134081.1|VDY99428.1|1234049_1234343_+|CRISPR-associated-protein
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>LR134081.1|VDY99426.1|1233129_1234053_+|CRISPR-associated-protein
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARHPAESDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>LR134081.1|VDY99424.1|1232482_1233133_+|CRISPR-associated-protein
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESEMFTIECRPFASELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>LR134081.1|VDY99422.1|1231753_1232266_+|CRISPR-associated-protein
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKSRYFSRREELSDPDLLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQEGLRHPVFSALSGAKKSSAGITTRAVTDRRQRV
>LR134081.1|VDY99420.1|1230687_1231743_+|CRISPR-associated-protein
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPIEEDLALLRKDRIAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECVSFDVMNKQGSMKDVLDFICA
>LR134081.1|VDY99418.1|1230136_1230673_+|CRISPR-associated-protein-Cse2
MSIVKEEHKATLRKWHEELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFTRLSAVKTPDDLLRQLRRAVKLLNGSVNLISLAEDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>LR134081.1|VDY99416.1|1229810_1230140_+|CRISPR-associated-protein
MKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDPDELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQNAKAAREKKQEAAE
>LR134081.1|VDY99414.1|1228578_1229793_+|CRISPR-associated-protein
MNSFSLLTTSWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKDHRRWDDIWEDGLESEKLREALLSLEHAFQFGPDSPSFMQDFEALTGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWLNVMPQDEADLPLPKKFDDLIFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQNDALLNLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKKARYRNCGWLRKRLHGF
>LR134081.1|VDY99412.1|1225781_1228481_+|CRISPR-associated-helicase-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRDEKEGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLHPQLKVPEGARKNYEKISHSTLGYWLWHHYLSECEELLPASSLSTRKLKRVIAMWMPMTTGHHGRPPDRIDELDNFLPEDKAAARDFLLEIKPLFPQLEIPAFWDDDEGVELIKQLSWYISATVVLADWTGSSTRFFPRVAQTMDIEDYWQKALVQAQNALTVFPPKAETAPFTGINTLFPFIENPKPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLFFGLPTMATANAMYDRLVKTWLSFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGKLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSYILEGLIERQVRGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVHSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKNCSLKRSSQVIVCTQVIEQSVDIDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGVIQMPHSARLLIESVYGEDVVMPDGFARSEQEQVGKYYCDRSMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLASCINGVVKPYASGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEVLRQWCIEQRQDPEMANVILVTDDESCGYSATEGLIGKVD
>LR134081.1|VDY99410.1|1224438_1225191_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKGNVGYTKGKYCRIN
>LR134081.1|VDY99430.1|1235274_1236195_-|alkaline-phosphatase-isozyme-conversion-protein
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKIIRKALGVVMTQKYSTKRALLYFRWKRLTGILGIRMVISNAQKQPHSLREIAGMT
>LR134081.1|VDY99433.1|1236446_1237355_+|sulfate-adenylyltransferase
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQQGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>LR134081.1|VDY99435.1|1237356_1238784_+|sulfate-adenylyltransferase
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>LR134081.1|VDY99437.1|1238783_1239389_+|adenosine-5-phosphosulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELGNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>LR134081.1|VDY99439.1|1239438_1239762_+|putative-cytochrome-oxidase-subunit
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>LR134081.1|VDY99441.1|1239955_1240267_+|cell-division-protein
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>LR134081.1|VDY99443.1|1240285_1240996_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVTRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>LR134081.1|VDY99445.1|1240995_1241475_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>LR134081.1|VDY99447.1|1241471_1242521_+|tRNA-pseudouridine-synthase-D
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>LR134081.1|VDY99449.1|1242501_1243263_+|stationary-phase-survival-protein-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLEQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHNAQDVVSDWLNSVGVGTQW

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Crispr_ID: LR134081_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134081_3

1730353-1730470

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134081_3

>merge|LR134081|3|1730353-1730470|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>LR134081|3|3|1730353-1730470|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
LR134081.1\|VDZ00463.1\|1730489_1732775_-\|ribonucleoside-diphosphate-reductase	unknown	unknown	gnl\|CDD\|181649
LR134081.1\|VDZ00477.1\|1743460_1744606_+\|large-extracellular-alpha-helical-protein	unknown	unknown	gnl\|CDD\|225248
LR134081.1\|VDZ00459.1\|1728871_1729126_-\|putative-ferredoxin	unknown	unknown	gnl\|CDD\|182668
LR134081.1\|VDZ00447.1\|1725583_1725715_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134081.1\|VDZ00465.1\|1733469_1737222_+\|adhesin	unknown	unknown	gnl\|CDD\|182059
LR134081.1\|VDZ00443.1\|1723190_1724111_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
LR134081.1\|VDZ00457.1\|1728563_1728818_+\|pH-inducible-protein-involved-in-stress-response-(putative-kinase)	unknown	unknown	gnl\|CDD\|182136
LR134081.1\|VDZ00471.1\|1739726_1740860_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
LR134081.1\|VDZ00473.1\|1741008_1742697_+\|putative-membrane-protein-YfaA	unknown	unknown	gnl\|CDD\|227030
LR134081.1\|VDZ00449.1\|1725868_1726747_-\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176102
LR134081.1\|VDZ00467.1\|1737362_1738085_-\|3-demethylubiquinone-9-3-methyltransferase	unknown	unknown	gnl\|CDD\|235350
LR134081.1\|VDZ00451.1\|1726898_1727555_+\|putative-antibiotic-efflux-protein	unknown	unknown	gnl\|CDD\|341042
LR134081.1\|VDZ00475.1\|1742693_1743317_+\|protein	unknown	unknown	gnl\|CDD\|225774
LR134081.1\|VDZ00445.1\|1724334_1725405_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134081.1\|VDZ00469.1\|1738231_1739713_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
LR134081.1\|VDZ00455.1\|1728168_1728534_+\|pH-inducible-protein-involved-in-stress-response-(putative-kinase)	unknown	unknown	gnl\|CDD\|182136
LR134081.1\|VDZ00453.1\|1727551_1728088_+\|putative-antibiotic-efflux-protein	unknown	unknown	gnl\|CDD\|341042
LR134081.1\|VDZ00479.1\|1744566_1747854_+\|large-extracellular-alpha-helical-protein	unknown	unknown	gnl\|CDD\|225248
LR134081.1\|VDZ00481.1\|1747854_1749501_+\|protein	unknown	unknown	gnl\|CDD\|227732
LR134081.1\|VDZ00461.1\|1729125_1730256_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|181647

Protein	Function_ID	Function_description	E-value
LR134081.1\|VDZ00463.1\|1730489_1732775_-\|ribonucleoside-diphosphate-reductase	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
LR134081.1\|VDZ00477.1\|1743460_1744606_+\|large-extracellular-alpha-helical-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	6.15257e-86
LR134081.1\|VDZ00459.1\|1728871_1729126_-\|putative-ferredoxin	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
LR134081.1\|VDZ00473.1\|1741008_1742697_+\|putative-membrane-protein-YfaA	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
LR134081.1\|VDZ00465.1\|1733469_1737222_+\|adhesin	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
LR134081.1\|VDZ00443.1\|1723190_1724111_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
LR134081.1\|VDZ00457.1\|1728563_1728818_+\|pH-inducible-protein-involved-in-stress-response-(putative-kinase)	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	4.43903e-55
LR134081.1\|VDZ00449.1\|1725868_1726747_-\|putative-transcriptional-regulator	gnl\|CDD\|176102	cd05466, PBP2_LTTR_substrate, The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily. This model and hierarchy represent the the substrate-binding domain of the LysR-type transcriptional regulators that form the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, oxidative stress responses, nodule formation of nitrogen-fixing bacteria, synthesis of virulence factors, toxin production, attachment and secretion, to name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.9401e-45
LR134081.1\|VDZ00467.1\|1737362_1738085_-\|3-demethylubiquinone-9-3-methyltransferase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	3.89529e-170
LR134081.1\|VDZ00451.1\|1726898_1727555_+\|putative-antibiotic-efflux-protein	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.0553e-46
LR134081.1\|VDZ00475.1\|1742693_1743317_+\|protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	6.33736e-138
LR134081.1\|VDZ00471.1\|1739726_1740860_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
LR134081.1\|VDZ00469.1\|1738231_1739713_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
LR134081.1\|VDZ00455.1\|1728168_1728534_+\|pH-inducible-protein-involved-in-stress-response-(putative-kinase)	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	4.42243e-85
LR134081.1\|VDZ00453.1\|1727551_1728088_+\|putative-antibiotic-efflux-protein	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.23989e-41
LR134081.1\|VDZ00479.1\|1744566_1747854_+\|large-extracellular-alpha-helical-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
LR134081.1\|VDZ00481.1\|1747854_1749501_+\|protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	5.90367e-127
LR134081.1\|VDZ00461.1\|1729125_1730256_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0

>LR134081.1|VDZ00461.1|1729125_1730256_-|ribonucleotide-diphosphate-reductase-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL
>LR134081.1|VDZ00459.1|1728871_1729126_-|putative-ferredoxin
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>LR134081.1|VDZ00457.1|1728563_1728818_+|pH-inducible-protein-involved-in-stress-response-(putative-kinase)
MLKAVALAFKKMHSVNRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>LR134081.1|VDZ00455.1|1728168_1728534_+|pH-inducible-protein-involved-in-stress-response-(putative-kinase)
MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAGMQ
>LR134081.1|VDZ00453.1|1727551_1728088_+|putative-antibiotic-efflux-protein
MTFSYAGVSAFLALYARELNLMSAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYPCLLFFTVGLVVLGYTQGSVMMVVSGALIGIGYGSVTPVFQTQIISSVEPHKIGVANSLFFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVALVVAKEIH
>LR134081.1|VDZ00451.1|1726898_1727555_+|putative-antibiotic-efflux-protein
MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLYASPDKAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILVLSSLAFLVVTALYPFCHSIESLLFIRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWEAFNMAFWLCTGVAAVGIILSLIMTVPPVISHADGSKPKMGFAAMFDRAALRLPWLHSL
>LR134081.1|VDZ00449.1|1725868_1726747_-|putative-transcriptional-regulator
MTLTQINSLLAVLDYGGFTEASKRLFMTQSAVSQAIAALEQELGVNILLRDRRKAIQLTTAGHRIVQHLRAINREVNAVKEIAEQEKQNPQRTLRLGCFPSVCACILPVVIRYFEIHHPNIKIIPFEENSTAIIDSLQNESIDAGFVHFPVSGMYSVPIYQDKFTVVLPPNHALAKNSTITVEELMGEPLIISKGRYELSIMALFKEKNITPQIKYEFNHPDTAISFIRQGLGIALLPELTLKTIADELCSVPLEPTFYRQISLLAKEKPVEGSPLFLLQMCTEQLVVSGKI
>LR134081.1|VDZ00447.1|1725583_1725715_-|Uncharacterised-protein
MTPGRNRYEAPDSLSNPIVESNDTPANSTQFTLEPFSIFKWDT
>LR134081.1|VDZ00445.1|1724334_1725405_-|Uncharacterised-protein
MPNTSIHLSRCNILQNNKLQPAEIYKESQQTAKLEFFCDEFLKISQSRYGLSTSTDSIANLLAFFTKASDAIDSIKTQKIDVHSYGFVPIRHFVEHVITYKNEFAADYEPYTLTFTRGENNEGILSVESKEGFISQRTINLNEYETAINIINEHVIKENIHNTVQSPTEKDISKINSSDKPYKTSSKESIKSQLYSDQKNIQTCYYILRKNTEWYKYASSEERYDKFKNSSKEIKNTYKQIVQAQKKLNQMKYINKLSGELIDITDKKLAPLINDSFSYTRDFFAYSKQEKNIFTFDNSKFVDPKEKEGLMVQHSNGQLVITGKYCPEGVQTAFTQEQYDKLIRYINIFFTFPKLE
>LR134081.1|VDZ00443.1|1723190_1724111_+|glycerophosphodiester-phosphodiesterase
MAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGVNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDALQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>LR134081.1|VDZ00463.1|1730489_1732775_-|ribonucleoside-diphosphate-reductase
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTQYEQDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>LR134081.1|VDZ00465.1|1733469_1737222_+|adhesin
MRIIFLRKEYLSLLPSMIASLFSANGVAAAIDLCQGYDIKASCHASRQSLSGITQVWSIADGQWLVFSDMTNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNAVFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVILGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFVHSLTGFQNGTLNIDAGGNVTVNEGSFAGTIEGAGQLTIAQNGSYVLAGASSMALTGDIVVDDGAVLSLEGDAADLAALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVRLANDNQYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDNQQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISNGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTTGAVSLQNGVAGDTLTVNGDYTGGGTLLFDSELNGDDSASDQLVLNGNTAGNTTVVINPITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLQAANQAFMMERRDHAGGDGQMLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDNWLQYAWFSNDVSEQDDGVDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>LR134081.1|VDZ00467.1|1737362_1738085_-|3-demethylubiquinone-9-3-methyltransferase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYTPITNTFKLGPGVDVNYMLHTQNK
>LR134081.1|VDZ00469.1|1738231_1739713_+|DNA-gyrase-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKTARRIQRAAGSDRGTAAYSW
>LR134081.1|VDZ00471.1|1739726_1740860_+|DNA-gyrase-subunit-A
MEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVEGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>LR134081.1|VDZ00473.1|1741008_1742697_+|putative-membrane-protein-YfaA
MSGEKKAKGWQFYGLVGVGVVALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAAISDSQLSKTEISSIKINSETIPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDEQQDTEATAIASDLLSGKKRWQASFGLEERAAEKTPVRLRIVASARLLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>LR134081.1|VDZ00475.1|1742693_1743317_+|protein
MRHVLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANEALKVHDSKWLKNNGFSNQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMAWKDTRWIPNDSNPNFIGIYRLNFLAR
>LR134081.1|VDZ00477.1|1743460_1744606_+|large-extracellular-alpha-helical-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYCIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELHLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVKLDGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLMQTVDVTLDARNGGREVSACQKMPLPEVMSYVLLTAIRSIAAVFAWQTTSSHISRLV
>LR134081.1|VDZ00479.1|1744566_1747854_+|large-extracellular-alpha-helical-protein
MANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFDKPGNYNLTLRDKDGLILAGLSHAVSGKGSMSHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDSRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDPRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATLAAAILSGLTAEQSTIERALVMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSSGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>LR134081.1|VDZ00481.1|1747854_1749501_+|protein
MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGVTKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTMLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTSVKPGVLNGRYRVTFANGNHITFVSHGETTLLTEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMTAWTQDLIYAGDPVHYHGSRATEGTLSWRQAMAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKMPQWRRILQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD

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Crispr_ID: LR134081_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134081_5

3399152-3399300

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTACGGCAGTGAAC	PILER-CR

2 spacers

The CRISPR arrays of LR134081_5

>merge|LR134081|5|3399152-3399300|CRISPRCasFinder,PILER-CR
CATTTTATCTGCCTGTACGGCAGTGAACATGGTGGGCGGGTGGAGTATGTTACCAGTGAATTTCTAAGCTGCCTGTACGGCAGTGAACGTTTGCTGCAACCGCTAGCCAAGACGGTAGGTTTTTCTAAGCTGCCTGTACGGCAGTGAAC

>LR134081|5|5|3399152-3399300|CRISPRCasFinder
CATTTTATCTGCCTGTACGGCAGTGAAC	ATGGTGGGCGGGTGGAGTATGTTACCAGTGAA
TTTCTAAGCTGCCTGTACGGCAGTGAAC	GTTTGCTGCAACCGCTAGCCAAGACGGTAGGTT
TTTCTAAGCTGCCTGTACGGCAGTGAAC

>LR134081|5|3|3399160-3399300|PILER-CR
CTGCCTGTACGGCAGTGAACATGGTGGGCGGGT	GGAGTATGTTACCAGTGAATTTCTAAGCTGCC
TGTACGGCAGTGAACGTTTGCTGCAACCGCTAG	CCAAGACGGTAGGTTTTTCTAAGCTGCC
TGTACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134081.1\|VDZ04053.1\|3396154_3397021_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|236865
LR134081.1\|VDZ04057.1\|3397676_3398264_+\|leucyl/phenylalanyl-tRNA-protein-transferase	unknown	unknown	gnl\|CDD\|234720
LR134081.1\|VDZ04055.1\|3397065_3397425_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|236865
LR134081.1\|VDZ04045.1\|3391908_3392403_-\|leucine-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|183009
LR134081.1\|VDZ04069.1\|3404701_3405817_-\|macrolide-specific-efflux-protein	unknown	unknown	gnl\|CDD\|183211
LR134081.1\|VDZ04051.1\|3395802_3396051_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|236865
LR134081.1\|VDZ04063.1\|3401818_3402139_-\|ATP-dependent-Clp-protease-adaptor-protein	unknown	unknown	gnl\|CDD\|178809
LR134081.1\|VDZ04049.1\|3394167_3395802_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|236870
LR134081.1\|VDZ04041.1\|3386897_3387509_-\|outer-membrane-lipoprotein-carrier-protein	unknown	unknown	gnl\|CDD\|129638
LR134081.1\|VDZ04059.1\|3398548_3398767_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
LR134081.1\|VDZ04079.1\|3411200_3412853_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
LR134081.1\|VDZ04043.1\|3387667_3391774_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
LR134081.1\|VDZ04065.1\|3402461_3402686_+\|stationary-phase/starvation-inducible-regulatory-protein-CspD	unknown	unknown	gnl\|CDD\|77494
LR134081.1\|VDZ04061.1\|3399511_3401788_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|236828
LR134081.1\|VDZ04077.1\|3410157_3411057_+\|transporter	unknown	unknown	gnl\|CDD\|225287
LR134081.1\|VDZ04075.1\|3409004_3409700_+\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
LR134081.1\|VDZ04067.1\|3402758_3404705_-\|macrolide-export-ATP-binding/permease-protein	unknown	unknown	gnl\|CDD\|182528
LR134081.1\|VDZ04071.1\|3405931_3406924_+\|virulence-protein	unknown	unknown	gnl\|CDD\|225537
LR134081.1\|VDZ04073.1\|3406920_3408579_-\|nucleoside-triphosphate-hydrolase-domain	unknown	unknown	gnl\|CDD\|226121
LR134081.1\|VDZ04047.1\|3392948_3393914_+\|thioredoxin-reductase	unknown	unknown	gnl\|CDD\|182343

Protein	Function_ID	Function_description	E-value
LR134081.1\|VDZ04053.1\|3396154_3397021_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	2.16455e-174
LR134081.1\|VDZ04057.1\|3397676_3398264_+\|leucyl/phenylalanyl-tRNA-protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.91731e-119
LR134081.1\|VDZ04055.1\|3397065_3397425_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	1.58937e-61
LR134081.1\|VDZ04045.1\|3391908_3392403_-\|leucine-responsive-transcriptional-regulator	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
LR134081.1\|VDZ04069.1\|3404701_3405817_-\|macrolide-specific-efflux-protein	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
LR134081.1\|VDZ04051.1\|3395802_3396051_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	1.19036e-43
LR134081.1\|VDZ04063.1\|3401818_3402139_-\|ATP-dependent-Clp-protease-adaptor-protein	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
LR134081.1\|VDZ04049.1\|3394167_3395802_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
LR134081.1\|VDZ04041.1\|3386897_3387509_-\|outer-membrane-lipoprotein-carrier-protein	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
LR134081.1\|VDZ04059.1\|3398548_3398767_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
LR134081.1\|VDZ04079.1\|3411200_3412853_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
LR134081.1\|VDZ04043.1\|3387667_3391774_-\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
LR134081.1\|VDZ04065.1\|3402461_3402686_+\|stationary-phase/starvation-inducible-regulatory-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
LR134081.1\|VDZ04061.1\|3399511_3401788_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
LR134081.1\|VDZ04077.1\|3410157_3411057_+\|transporter	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	1.32789e-118
LR134081.1\|VDZ04075.1\|3409004_3409700_+\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144
LR134081.1\|VDZ04067.1\|3402758_3404705_-\|macrolide-export-ATP-binding/permease-protein	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
LR134081.1\|VDZ04071.1\|3405931_3406924_+\|virulence-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	9.72278e-133
LR134081.1\|VDZ04073.1\|3406920_3408579_-\|nucleoside-triphosphate-hydrolase-domain	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
LR134081.1\|VDZ04047.1\|3392948_3393914_+\|thioredoxin-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0

>LR134081.1|VDZ04059.1|3398548_3398767_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>LR134081.1|VDZ04057.1|3397676_3398264_+|leucyl/phenylalanyl-tRNA-protein-transferase
MAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
>LR134081.1|VDZ04055.1|3397065_3397425_+|ABC-transporter-ATP-binding-protein/permease
MHLFSATLRDNLLLASPGSSDEALSEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTIDFADSLVSNK
>LR134081.1|VDZ04053.1|3396154_3397021_+|ABC-transporter-ATP-binding-protein/permease
MLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPYPA
>LR134081.1|VDZ04051.1|3395802_3396051_+|ABC-transporter-ATP-binding-protein/permease
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITVLPGVILNVW
>LR134081.1|VDZ04049.1|3394167_3395802_+|ABC-transporter-ATP-binding-protein/permease
MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNVLSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
>LR134081.1|VDZ04047.1|3392948_3393914_+|thioredoxin-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>LR134081.1|VDZ04045.1|3391908_3392403_-|leucine-responsive-transcriptional-regulator
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>LR134081.1|VDZ04043.1|3387667_3391774_-|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQQQPVEQQPIVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQQQYQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQSAAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>LR134081.1|VDZ04041.1|3386897_3387509_-|outer-membrane-lipoprotein-carrier-protein
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>LR134081.1|VDZ04061.1|3399511_3401788_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>LR134081.1|VDZ04063.1|3401818_3402139_-|ATP-dependent-Clp-protease-adaptor-protein
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>LR134081.1|VDZ04065.1|3402461_3402686_+|stationary-phase/starvation-inducible-regulatory-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>LR134081.1|VDZ04067.1|3402758_3404705_-|macrolide-export-ATP-binding/permease-protein
MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>LR134081.1|VDZ04069.1|3404701_3405817_-|macrolide-specific-efflux-protein
MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>LR134081.1|VDZ04071.1|3405931_3406924_+|virulence-protein
MVKSTSCTTIDFMNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
>LR134081.1|VDZ04073.1|3406920_3408579_-|nucleoside-triphosphate-hydrolase-domain
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>LR134081.1|VDZ04075.1|3409004_3409700_+|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>LR134081.1|VDZ04077.1|3410157_3411057_+|transporter
MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILMAFFSA
>LR134081.1|VDZ04079.1|3411200_3412853_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSEVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

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Crispr_ID: LR134081_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134081_6

4622011-4622160

Orphan

Consensus_repeat	Method
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134081_6

>merge|LR134081|6|4622011-4622160|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCATGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

>LR134081|6|6|4622011-4622160|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCA
TGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
LR134081.1\|VDZ05629.1\|4622327_4622771_+\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
LR134081.1\|VDZ05622.1\|4613903_4615223_+\|Gnt-II-system-L-idonate-transporter	unknown	unknown	gnl\|CDD\|129873
LR134081.1\|VDZ05634.1\|4628195_4629200_+\|ornithine-carbamoyltransferase-1	unknown	unknown	gnl\|CDD\|179587
LR134081.1\|VDZ05627.1\|4619248_4620175_-\|putative-permease	unknown	unknown	gnl\|CDD\|185075
LR134081.1\|VDZ05631.1\|4625679_4626876_-\|inner-membrane-protein	unknown	unknown	gnl\|CDD\|226719
LR134081.1\|VDZ05630.1\|4622770_4625626_+\|valyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|235582
LR134081.1\|VDZ05638.1\|4631642_4632236_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
LR134081.1\|VDZ05624.1\|4616364_4617867_+\|ATPase	unknown	unknown	gnl\|CDD\|283518
LR134081.1\|VDZ05635.1\|4629272_4630829_-\|protein	unknown	unknown	unknown
LR134081.1\|VDZ05625.1\|4618561_4618879_-\|putative-permease	unknown	unknown	gnl\|CDD\|237900
LR134081.1\|VDZ05620.1\|4612022_4613054_+\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|182130
LR134081.1\|VDZ05626.1\|4618826_4619207_-\|putative-permease	unknown	unknown	gnl\|CDD\|237900
LR134081.1\|VDZ05628.1\|4620462_4621974_+\|cytosol-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
LR134081.1\|VDZ05623.1\|4615288_4616287_+\|L-idonate-regulatory-protein	unknown	unknown	gnl\|CDD\|380489
LR134081.1\|VDZ05632.1\|4627068_4627572_+\|putative-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
LR134081.1\|VDZ05633.1\|4627617_4628034_-\|RNase-E-inhibitor-protein	unknown	unknown	gnl\|CDD\|236876
LR134081.1\|VDZ05621.1\|4613077_4613842_+\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181225
LR134081.1\|VDZ05637.1\|4631343_4631499_-\|toxin-antitoxin-biofilm-protein	unknown	unknown	gnl\|CDD\|129133
LR134081.1\|VDZ05636.1\|4631047_4631347_-\|toxin-antitoxin-biofilm-protein	unknown	unknown	gnl\|CDD\|225345
LR134081.1\|VDZ05619.1\|4611242_4611806_-\|D-gluconate-kinase	unknown	unknown	gnl\|CDD\|182097

Protein	Function_ID	Function_description	E-value
LR134081.1\|VDZ05629.1\|4622327_4622771_+\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
LR134081.1\|VDZ05622.1\|4613903_4615223_+\|Gnt-II-system-L-idonate-transporter	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
LR134081.1\|VDZ05634.1\|4628195_4629200_+\|ornithine-carbamoyltransferase-1	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
LR134081.1\|VDZ05627.1\|4619248_4620175_-\|putative-permease	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
LR134081.1\|VDZ05631.1\|4625679_4626876_-\|inner-membrane-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	1.62032e-151
LR134081.1\|VDZ05630.1\|4622770_4625626_+\|valyl-tRNA-synthetase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
LR134081.1\|VDZ05638.1\|4631642_4632236_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.52762e-10
LR134081.1\|VDZ05624.1\|4616364_4617867_+\|ATPase	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
LR134081.1\|VDZ05625.1\|4618561_4618879_-\|putative-permease	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	2.38687e-34
LR134081.1\|VDZ05620.1\|4612022_4613054_+\|L-idonate-5-dehydrogenase	gnl\|CDD\|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0
LR134081.1\|VDZ05626.1\|4618826_4619207_-\|putative-permease	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	5.40874e-48
LR134081.1\|VDZ05628.1\|4620462_4621974_+\|cytosol-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
LR134081.1\|VDZ05623.1\|4615288_4616287_+\|L-idonate-regulatory-protein	gnl\|CDD\|380489	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. This group represents the ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of GntR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding, which in turn changes the DNA binding affinity of the repressor.	1.1057e-108
LR134081.1\|VDZ05632.1\|4627068_4627572_+\|putative-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	9.50849e-19
LR134081.1\|VDZ05633.1\|4627617_4628034_-\|RNase-E-inhibitor-protein	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
LR134081.1\|VDZ05621.1\|4613077_4613842_+\|gluconate-5-dehydrogenase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	0
LR134081.1\|VDZ05637.1\|4631343_4631499_-\|toxin-antitoxin-biofilm-protein	gnl\|CDD\|129133	TIGR00022, Uncharacterized_protein_HI_0227, YhcH/YjgK/YiaL family protein. This family consists of conserved hypothetical proteins, about 150 amino acids in length. Members with limited information include YhcH, a possible sugar isomerase of sialic acid catabolism, and YjgK. [Unknown function, General].	1.24734e-17
LR134081.1\|VDZ05636.1\|4631047_4631347_-\|toxin-antitoxin-biofilm-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.8874e-48
LR134081.1\|VDZ05619.1\|4611242_4611806_-\|D-gluconate-kinase	gnl\|CDD\|182097	PRK09825, idnK, gluconokinase.	4.94326e-125

>LR134081.1|VDZ05628.1|4620462_4621974_+|cytosol-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>LR134081.1|VDZ05627.1|4619248_4620175_-|putative-permease
MRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTS
>LR134081.1|VDZ05626.1|4618826_4619207_-|putative-permease
MWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAVDATFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGCWRSAANWW
>LR134081.1|VDZ05625.1|4618561_4618879_-|putative-permease
MGRCLVWDAGAAQRTGGDAGFWFHPYAGCAVGDENRHSAGLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKVTKSRWHQYLCL
>LR134081.1|VDZ05624.1|4616364_4617867_+|ATPase
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGVAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDDVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRKR
>LR134081.1|VDZ05623.1|4615288_4616287_+|L-idonate-regulatory-protein
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEEPVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
>LR134081.1|VDZ05622.1|4613903_4615223_+|Gnt-II-system-L-idonate-transporter
MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
>LR134081.1|VDZ05621.1|4613077_4613842_+|gluconate-5-dehydrogenase
MNDLFSLAGKNILITGSAQGIGFLLASGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV
>LR134081.1|VDZ05620.1|4612022_4613054_+|L-idonate-5-dehydrogenase
MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF
>LR134081.1|VDZ05619.1|4611242_4611806_-|D-gluconate-kinase
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRIRAKEGSASDQRCE
>LR134081.1|VDZ05629.1|4622327_4622771_+|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>LR134081.1|VDZ05630.1|4622770_4625626_+|valyl-tRNA-synthetase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTNVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>LR134081.1|VDZ05631.1|4625679_4626876_-|inner-membrane-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFFSCLVFVFFYFAILMTVSADMPLVGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGFWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTAYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYSNDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIMPSLPFL
>LR134081.1|VDZ05632.1|4627068_4627572_+|putative-acetyltransferase
MNNIAPQSPVMRRLTLQDNPVIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>LR134081.1|VDZ05633.1|4627617_4628034_-|RNase-E-inhibitor-protein
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>LR134081.1|VDZ05634.1|4628195_4629200_+|ornithine-carbamoyltransferase-1
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
>LR134081.1|VDZ05635.1|4629272_4630829_-|protein
MNNFARNAEGQDNTRNILDPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKFVMNNPEGERADLSKVEIEITLSAFTTMGTRQGHTAIIFQQPDGSTNRYEGKSFERKDESSLHLITNKILACYQREANKEIARLLNIPQELNNSQDLNNSQVSCKDSVDSTITDLLEKPLNNALLAIRKEHLLLMPYVCNESISYLLGEKGILKEIDDLNAVNNYLLNNKKATNNEINDIKVNLSHILIDSLDDAKVNLTPVIDSILETFLKSPYINDVRILDWCFNKRMQYFGDSEKIKYACSVINHIDFSRDQSKGFSCDQSKIKIAETLFFNLDKEPYKNSRKLQELIWDKLVAYVNDFNLSNQEKSRLILRLFDDVKSLFDEVPVSILVNDIFLKGFFMKQPDFAKWYFYQLLKKYEGEQLYLNELGYVYGNEEKTNEIVKKHPGYVVEIFEEKMGNELKIRTRMMEILRDGKINICEYINKEQLEKLNPPEDLRIAIKKLGWNN
>LR134081.1|VDZ05636.1|4631047_4631347_-|toxin-antitoxin-biofilm-protein
MTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPARVRKAVVKMLMA
>LR134081.1|VDZ05637.1|4631343_4631499_-|toxin-antitoxin-biofilm-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLSRKI
>LR134081.1|VDZ05638.1|4631642_4632236_-|TetR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLAEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARRHPQSAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134081_2	2.9\|1234963\|33\|LR134081\|PILER-CR	1234963-1234995	33	MN856003	Bacteriophage sp. isolate 1, complete genome	43533-43565	1	0.97
LR134081_2	2.19\|1234956\|32\|LR134081\|CRISPRCasFinder,CRT	1234956-1234987	32	MN856003	Bacteriophage sp. isolate 1, complete genome	43533-43564	1	0.969
LR134081_4	4.1\|3259063\|40\|LR134081\|CRISPRCasFinder	3259063-3259102	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	1	0.975
LR134081_1	1.2\|1208131\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208131-1208162	32	NC_048766	Pantoea phage vB_PagM_AAM37, complete genome	4684-4715	6	0.812
LR134081_1	1.2\|1208131\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208131-1208162	32	MK095606	Pantoea phage vB_PagS_AAS23, complete genome	1556-1587	7	0.781
LR134081_1	1.2\|1208131\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208131-1208162	32	MG732930	Enterobacter phage Ec_L1, complete genome	26019-26050	7	0.781
LR134081_1	1.3\|1208192\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208192-1208223	32	NZ_CP045223	Achromobacter xylosoxidans strain DN002 plasmid unnamed	184789-184820	7	0.781
LR134081_1	1.9\|1208559\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208559-1208590	32	AJ564013	Bacteriophage PY54 complete genome	41559-41590	7	0.781
LR134081_1	1.9\|1208559\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208559-1208590	32	NC_005069	Yersinia phage PY54, complete genome	41559-41590	7	0.781
LR134081_1	1.2\|1208131\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208131-1208162	32	JN022534	Xanthomonas phage vB_XveM_DIBBI, complete genome	4380-4411	8	0.75
LR134081_1	1.3\|1208192\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208192-1208223	32	NC_031068	Pectobacterium phage PP16, complete genome	34801-34832	8	0.75
LR134081_1	1.3\|1208192\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208192-1208223	32	MN271656	Pectobacterium phage MA2, complete genome	32877-32908	8	0.75
LR134081_2	2.15\|1234712\|32\|LR134081\|CRISPRCasFinder,CRT	1234712-1234743	32	MH617380	Microviridae sp. isolate ctcc639, complete genome	3153-3184	8	0.75
LR134081_2	2.17\|1234834\|32\|LR134081\|CRISPRCasFinder,CRT	1234834-1234865	32	NZ_CP021170	Paenibacillus bovis strain BD3526 plasmid unnamed1, complete sequence	47960-47991	8	0.75
LR134081_2	2.19\|1234956\|32\|LR134081\|CRISPRCasFinder,CRT	1234956-1234987	32	NZ_CP034699	Salmonella enterica subsp. enterica serovar Karamoja strain RSE40 plasmid pRSE40, complete sequence	44158-44189	8	0.75
LR134081_2	2.19\|1234956\|32\|LR134081\|CRISPRCasFinder,CRT	1234956-1234987	32	NZ_CP034710	Salmonella enterica subsp. enterica serovar Karamoja strain RSE21 plasmid pRSE21, complete sequence	7316-7347	8	0.75
LR134081_2	2.5\|1234719\|33\|LR134081\|PILER-CR	1234719-1234751	33	MH617380	Microviridae sp. isolate ctcc639, complete genome	3153-3185	9	0.727
LR134081_2	2.17\|1234834\|32\|LR134081\|CRISPRCasFinder,CRT	1234834-1234865	32	NZ_KU254577	Pseudomonas aeruginosa strain HN39 plasmid pHN39-SIM, complete sequence	224437-224468	9	0.719
LR134081_5	5.1\|3399180\|32\|LR134081\|CRISPRCasFinder	3399180-3399211	32	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9736-9767	9	0.719
LR134081_5	5.1\|3399180\|32\|LR134081\|CRISPRCasFinder	3399180-3399211	32	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9737-9768	9	0.719
LR134081_5	5.1\|3399180\|32\|LR134081\|CRISPRCasFinder	3399180-3399211	32	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9736-9767	9	0.719
LR134081_5	5.3\|3399193\|32\|LR134081\|PILER-CR	3399193-3399224	32	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9736-9767	9	0.719
LR134081_5	5.3\|3399193\|32\|LR134081\|PILER-CR	3399193-3399224	32	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9737-9768	9	0.719
LR134081_5	5.3\|3399193\|32\|LR134081\|PILER-CR	3399193-3399224	32	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9736-9767	9	0.719
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	241792-241822	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	188655-188685	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	96868-96898	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	315190-315220	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	82591-82621	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	315191-315221	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	175988-176018	10	0.677
LR134081_1	1.1\|1208071\|31\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208071-1208101	31	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	314803-314833	10	0.677
LR134081_1	1.7\|1208437\|32\|LR134081\|PILER-CR,CRISPRCasFinder,CRT	1208437-1208468	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	249091-249122	10	0.688
LR134081_1	1.11\|1208681\|32\|LR134081\|CRISPRCasFinder,CRT	1208681-1208712	32	KX397366	Erwinia phage vB_EamM_ChrisDB, complete genome	18704-18735	10	0.688
LR134081_2	2.17\|1234834\|32\|LR134081\|CRISPRCasFinder,CRT	1234834-1234865	32	NZ_CP010826	Thermus aquaticus Y51MC23 plasmid pTA78, complete sequence	18642-18673	10	0.688

1. spacer 2.9|1234963|33|LR134081|PILER-CR matches to MN856003 (Bacteriophage sp. isolate 1, complete genome) position: , mismatch: 1, identity: 0.97

gcgtactgcttactccgtcatcgatgtatgagt	CRISPR spacer
gcgtgctgcttactccgtcatcgatgtatgagt	Protospacer
****.****************************

2. spacer 2.19|1234956|32|LR134081|CRISPRCasFinder,CRT matches to MN856003 (Bacteriophage sp. isolate 1, complete genome) position: , mismatch: 1, identity: 0.969

cgtactgcttactccgtcatcgatgtatgagt	CRISPR spacer
cgtgctgcttactccgtcatcgatgtatgagt	Protospacer
***.****************************

3. spacer 4.1|3259063|40|LR134081|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 1, identity: 0.975

gcgctgcggatcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
*********.******************************

4. spacer 1.2|1208131|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NC_048766 (Pantoea phage vB_PagM_AAM37, complete genome) position: , mismatch: 6, identity: 0.812

gaataccgattcataacggcgga-aatgtggat	CRISPR spacer
gaataccgattcatcacggcggataccgcgca-	Protospacer
************** ******** * .*.* *

5. spacer 1.2|1208131|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to MK095606 (Pantoea phage vB_PagS_AAS23, complete genome) position: , mismatch: 7, identity: 0.781

gaataccgattcataacggcgga-aatgtggat	CRISPR spacer
gattaccgattcataacggcggataccgccca-	Protospacer
** ******************** * .*.  *

6. spacer 1.2|1208131|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to MG732930 (Enterobacter phage Ec_L1, complete genome) position: , mismatch: 7, identity: 0.781

gaataccgattcataacggcggaaatgtggat--	CRISPR spacer
gagtaccgattcataacggcgg--ataccgctca	Protospacer
**.*******************  **.. * *

7. spacer 1.3|1208192|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045223 (Achromobacter xylosoxidans strain DN002 plasmid unnamed) position: , mismatch: 7, identity: 0.781

acgaaaaacaggctgcaagtctcg--ctgaccaa	CRISPR spacer
tcgaaaaacagcgtgcaagtctcgatctcgcc--	Protospacer
 **********  ***********  ** .**

8. spacer 1.9|1208559|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to AJ564013 (Bacteriophage PY54 complete genome) position: , mismatch: 7, identity: 0.781

gtcgctggaacggggcgaataaagaggggctc	CRISPR spacer
gccgctggaaaggggcgagtaaagagtctttc	Protospacer
*.******** *******.*******   .**

9. spacer 1.9|1208559|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NC_005069 (Yersinia phage PY54, complete genome) position: , mismatch: 7, identity: 0.781

gtcgctggaacggggcgaataaagaggggctc	CRISPR spacer
gccgctggaaaggggcgagtaaagagtctttc	Protospacer
*.******** *******.*******   .**

10. spacer 1.2|1208131|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to JN022534 (Xanthomonas phage vB_XveM_DIBBI, complete genome) position: , mismatch: 8, identity: 0.75

gaataccgattcataacggcggaaatgtggat--	CRISPR spacer
gagtaccgattcatcacggcgg--ataccgctca	Protospacer
**.*********** *******  **.. * *

11. spacer 1.3|1208192|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NC_031068 (Pectobacterium phage PP16, complete genome) position: , mismatch: 8, identity: 0.75

acgaaaaacaggctgcaagtctcgctgaccaa	CRISPR spacer
acggcgccaaggctgctactctcgctgaccaa	Protospacer
***. .   ******* * *************

12. spacer 1.3|1208192|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to MN271656 (Pectobacterium phage MA2, complete genome) position: , mismatch: 8, identity: 0.75

acgaaaaacaggctgcaagtctcgctgaccaa	CRISPR spacer
acggcgccaaggctgctactctcgctgaccaa	Protospacer
***. .   ******* * *************

13. spacer 2.15|1234712|32|LR134081|CRISPRCasFinder,CRT matches to MH617380 (Microviridae sp. isolate ctcc639, complete genome) position: , mismatch: 8, identity: 0.75

attacgacttccgcacgcacccaccgtttgta	CRISPR spacer
attacgacatccgcacgcccccacgtggtaca	Protospacer
******** ********* *****    *..*

14. spacer 2.17|1234834|32|LR134081|CRISPRCasFinder,CRT matches to NZ_CP021170 (Paenibacillus bovis strain BD3526 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gcgtttctggcgggggtagggaacgcccagaa	CRISPR spacer
atgctgcgggctggggtagggaacgctcagat	Protospacer
..*.* * *** **************.****

15. spacer 2.19|1234956|32|LR134081|CRISPRCasFinder,CRT matches to NZ_CP034699 (Salmonella enterica subsp. enterica serovar Karamoja strain RSE40 plasmid pRSE40, complete sequence) position: , mismatch: 8, identity: 0.75

cgtactgc-ttactccgtcatcgatgtatgagt	CRISPR spacer
-taacaacattacgtcgtcatcgatgtatgagg	Protospacer
   ** .* **** .*****************

16. spacer 2.19|1234956|32|LR134081|CRISPRCasFinder,CRT matches to NZ_CP034710 (Salmonella enterica subsp. enterica serovar Karamoja strain RSE21 plasmid pRSE21, complete sequence) position: , mismatch: 8, identity: 0.75

cgtactgc-ttactccgtcatcgatgtatgagt	CRISPR spacer
-taacaacattacgtcgtcatcgatgtatgagg	Protospacer
   ** .* **** .*****************

17. spacer 2.5|1234719|33|LR134081|PILER-CR matches to MH617380 (Microviridae sp. isolate ctcc639, complete genome) position: , mismatch: 9, identity: 0.727

gattacgacttccgcacgcacccaccgtttgta	CRISPR spacer
cattacgacatccgcacgcccccacgtggtaca	Protospacer
 ******** ********* *****    *..*

18. spacer 2.17|1234834|32|LR134081|CRISPRCasFinder,CRT matches to NZ_KU254577 (Pseudomonas aeruginosa strain HN39 plasmid pHN39-SIM, complete sequence) position: , mismatch: 9, identity: 0.719

gcgtttctggcgggggtagggaacgcccagaa	CRISPR spacer
gagggtctggcgggggtagggaagtccccagg	Protospacer
* *  ******************  *** ...

19. spacer 5.1|3399180|32|LR134081|CRISPRCasFinder matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

20. spacer 5.1|3399180|32|LR134081|CRISPRCasFinder matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

21. spacer 5.1|3399180|32|LR134081|CRISPRCasFinder matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

22. spacer 5.3|3399193|32|LR134081|PILER-CR matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

23. spacer 5.3|3399193|32|LR134081|PILER-CR matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

24. spacer 5.3|3399193|32|LR134081|PILER-CR matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 9, identity: 0.719

atggtgggcgggtggagtatgttaccagtgaa	CRISPR spacer
acaccgggcgggtggaacatgttaccaggaca	Protospacer
*.. .***********..********** . *

25. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

26. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

27. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

28. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

29. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

30. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

31. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

32. spacer 1.1|1208071|31|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.677

gctggataccgatcaattcaatatcgtttac	CRISPR spacer
cagtagcaccgattaaatcaatatcgtttaa	Protospacer
    ...******.** *************

33. spacer 1.7|1208437|32|LR134081|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

agtgaggcaatcaaatgacccgcccgcaatta	CRISPR spacer
agtgaggccataaaatgacccgccgagtggcc	Protospacer
******** ** ************ .  . .

34. spacer 1.11|1208681|32|LR134081|CRISPRCasFinder,CRT matches to KX397366 (Erwinia phage vB_EamM_ChrisDB, complete genome) position: , mismatch: 10, identity: 0.688

tttgctggaacccaaaactcagcgcacaggtt	CRISPR spacer
tgagctggaatccaaagctcagcgcatctacc	Protospacer
*  *******.*****.*********.  ...

35. spacer 2.17|1234834|32|LR134081|CRISPRCasFinder,CRT matches to NZ_CP010826 (Thermus aquaticus Y51MC23 plasmid pTA78, complete sequence) position: , mismatch: 10, identity: 0.688

gcgtttctggcgggggtagggaacgcccagaa	CRISPR spacer
agctttatggcgggggtaaggaacgctgattc	Protospacer
.  *** ***********.*******. *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

311280 : 317684

uncultured_Caudovirales_phage(66.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDY97481.1\|311280_312822_+\|transposase	transposase for ISEc12	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
VDY97483.1\|312836_313583_+\|transposase	transposase	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
VDY97485.1\|313999_315013_-	putative permease	NA	NA	NA	NA
VDY97487.1\|315119_315416_+	ArsR family transcriptional regulator	NA	NA	NA	NA
VDY97489.1\|315549_315723_-	arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.0e-15	69.6
VDY97491.1\|315731_315974_-	arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	4.3e-16	75.0
VDY97493.1\|315986_317276_-	arsenical pump membrane protein	A0A2H4J144	uncultured_Caudovirales_phage	4.6e-173	73.5
VDY97495.1\|317330_317684_-	DNA-binding transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	9.7e-25	50.9

DBSCAN-SWA_2

877729 : 940166

Moraxella_phage(20.0%)

transposase,integrase

attL 875618:875632|attR 891555:891569

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
875618:875632	attL	NA	NA	NA	NA
VDY98689.1\|877729_878365_-\|integrase	integrase family protein	B7SYF8	Stenotrophomonas_phage	2.4e-34	42.7
VDY98691.1\|878576_878996_-	ybl123	A0A1B0VMI6	Pseudomonas_phage	1.2e-26	50.4
VDY98693.1\|879290_879860_-	ybl125	NA	NA	NA	NA
VDY98695.1\|879956_880154_-	Aec78	NA	NA	NA	NA
VDY98697.1\|880165_880654_-	aec77	NA	NA	NA	NA
VDY98699.1\|880650_881025_-	phage protein	NA	NA	NA	NA
VDY98701.1\|881114_881483_-	antitoxin of the YeeV-YeeU toxin-antitoxin system; CP4-44 prophage	NA	NA	NA	NA
VDY98703.1\|881562_881784_-	CP4-44 prophage	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
VDY98705.1\|881870_882347_-	putative DNA repair protein	NA	NA	NA	NA
VDY98707.1\|882361_882847_-	anti-restriction protein	A9J566	Pseudomonas_phage	5.3e-13	31.7
VDY98709.1\|882937_883756_-	CP4-57 prophage protein	A0A2C9CX26	Yersinia_phage	4.2e-47	39.1
VDY98711.1\|883844_884078_-	CP4-6 prophage protein	NA	NA	NA	NA
VDY98713.1\|884083_884761_-	Uncharacterised protein	NA	NA	NA	NA
VDY98715.1\|884908_885589_-	putative DNA-binding protein	NA	NA	NA	NA
VDY98717.1\|885686_885863_+	Uncharacterised protein	NA	NA	NA	NA
VDY98719.1\|885791_886676_-	putative ATP/GTP-binding protein	NA	NA	NA	NA
VDY98721.1\|886860_887013_+	Uncharacterised protein	NA	NA	NA	NA
VDY98723.1\|887214_887388_-	Uncharacterised protein	NA	NA	NA	NA
VDY98725.1\|889621_889750_-	putative DNA-binding protein	NA	NA	NA	NA
VDY98727.1\|890418_891003_+	malate transporter	NA	NA	NA	NA
VDY98729.1\|891927_892140_+	iron-regulated outer membrane virulence protein	NA	NA	NA	NA
891555:891569	attR	NA	NA	NA	NA
VDY98731.1\|892307_892931_+	iron-regulated outer membrane virulence protein	NA	NA	NA	NA
VDY98733.1\|892894_893827_+	iron-regulated outer membrane virulence protein	NA	NA	NA	NA
VDY98735.1\|893811_893973_+	iron-regulated outer membrane virulence protein	NA	NA	NA	NA
VDY98737.1\|894106_895315_+\|transposase	transposase	A0A218MNI5	uncultured_virus	5.4e-51	49.7
VDY98739.1\|896375_896942_+	Protein of uncharacterised function (DUF3296)	NA	NA	NA	NA
VDY98741.1\|897189_897750_+	Uncharacterised protein	NA	NA	NA	NA
VDY98743.1\|897818_898052_+	putative regulatory protein	NA	NA	NA	NA
VDY98745.1\|898587_898866_+	Uncharacterised protein	NA	NA	NA	NA
VDY98747.1\|899132_899756_+	putative DNA-binding protein	NA	NA	NA	NA
VDY98749.1\|899853_900087_+	Uncharacterised protein	NA	NA	NA	NA
VDY98751.1\|900450_902217_+	putative hemolysin activator ShlB-type	A0A0R6PI85	Moraxella_phage	4.6e-22	25.5
VDY98753.1\|902229_910197_+	hemagglutinin-related protein	A0A0R6PJK4	Moraxella_phage	1.3e-28	33.5
VDY98755.1\|910193_911957_+	hemagglutinin-related protein	NA	NA	NA	NA
VDY98757.1\|911953_912340_+	Uncharacterised protein	NA	NA	NA	NA
VDY98759.1\|912370_912748_+	protein encoded within IS	A0A0P0ZBS5	Stx2-converting_phage	1.7e-56	98.1
VDY98761.1\|912914_913385_+	ImpA-related N-terminal family protein	NA	NA	NA	NA
VDY98763.1\|913368_913896_+	TraG-like protein, N-terminal region	NA	NA	NA	NA
VDY98765.1\|913905_914262_+	TraG-like protein, N-terminal region	NA	NA	NA	NA
VDY98767.1\|914642_915689_+	modification methylase	A0A0R6PG08	Moraxella_phage	2.0e-65	43.0
VDY98769.1\|915729_918654_+	ATPase	A0A1B5FPD5	Escherichia_phage	3.9e-34	24.3
VDY98771.1\|918667_920335_+	Uncharacterised protein	NA	NA	NA	NA
VDY98773.1\|921015_921282_+\|transposase	transposase	NA	NA	NA	NA
VDY98775.1\|921310_921631_+\|transposase	transposase	NA	NA	NA	NA
VDY98777.1\|921769_921859_+	Uncharacterised protein	NA	NA	NA	NA
VDY98779.1\|922492_924031_-	sensor histidine kinase	W8CYF6	Bacillus_phage	2.6e-21	27.9
VDY98781.1\|924090_924750_-	response regulator	W8CYM9	Bacillus_phage	1.8e-24	33.2
VDY98783.1\|924890_925490_+	putative transmembrane hydrogenase cytochrome b-type subunit oxidoreductase protein	NA	NA	NA	NA
VDY98785.1\|925489_926290_+	oxidoreductase	NA	NA	NA	NA
VDY98787.1\|926286_926529_+	pentapeptide MXKDX repeat protein	NA	NA	NA	NA
VDY98789.1\|927712_928138_+	hemolysin C	NA	NA	NA	NA
VDY98791.1\|928235_929594_+	hemolysin A	NA	NA	NA	NA
VDY98793.1\|929677_931309_+	hemolysin A	NA	NA	NA	NA
VDY98795.1\|931379_931928_+	alpha-hemolysin translocation ATP-binding protein HlyB	NA	NA	NA	NA
VDY98797.1\|931912_933502_+	alpha-hemolysin translocation ATP-binding protein HlyB	W8CYL7	Bacillus_phage	4.3e-48	31.0
VDY98799.1\|933520_934957_+	hemolysin D	NA	NA	NA	NA
VDY98801.1\|935397_935625_+	urea transporter	NA	NA	NA	NA
VDY98803.1\|935902_938947_+	cytotoxic necrotizing factor 1	NA	NA	NA	NA
VDY98805.1\|939467_939773_-\|transposase	putative transposase	A0A077SLK2	Escherichia_phage	1.1e-37	72.4
VDY98807.1\|939866_940166_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1002940 : 1051602

Bacillus_phage(28.57%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDY98953.1\|1002940_1003462_+\|transposase	transposase	NA	NA	NA	NA
VDY98955.1\|1003686_1004289_+\|transposase	transposase	A0A1B1P773	Bacillus_phage	1.3e-61	56.8
VDY98957.1\|1004423_1005182_-	peptidase	NA	NA	NA	NA
VDY98959.1\|1005459_1007451_+	transketolase	NA	NA	NA	NA
VDY98961.1\|1007670_1008450_-\|protease	putative membrane protease	A0A2C9D0H9	Yersinia_phage	3.6e-48	58.1
VDY98963.1\|1008425_1008578_-\|protease	putative membrane protease	NA	NA	NA	NA
VDY98965.1\|1008954_1009206_+	mannitol-specific cryptic PTS system IIIA component	NA	NA	NA	NA
VDY98967.1\|1009424_1009760_+	mannitol-specific cryptic PTS system EIICB component	NA	NA	NA	NA
VDY98969.1\|1009807_1010218_+	mannitol-specific cryptic PTS system EIICB component	NA	NA	NA	NA
VDY98971.1\|1010217_1010811_+	mannitol-specific cryptic PTS system EIICB component	NA	NA	NA	NA
VDY98973.1\|1010825_1011182_+	putative oxidoreductase	NA	NA	NA	NA
VDY98975.1\|1011178_1011997_+	putative oxidoreductase	NA	NA	NA	NA
VDY98977.1\|1012099_1012741_+	putative sugar-bisphosphatase	NA	NA	NA	NA
VDY98979.1\|1012776_1012968_+	putative sugar-bisphosphatase	NA	NA	NA	NA
VDY98980.1\|1013084_1013594_+	putative transcriptional regulator	NA	NA	NA	NA
VDY98982.1\|1013590_1014304_+	fructose transport system kinase	NA	NA	NA	NA
VDY98984.1\|1014275_1014953_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.9e-09	25.6
VDY98986.1\|1014946_1015624_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
VDY98988.1\|1015611_1016319_-	ABC transporter permease	NA	NA	NA	NA
VDY98990.1\|1016319_1016898_-	ABC-type transport system	NA	NA	NA	NA
VDY98992.1\|1016920_1017352_-	DNA-binding protein	NA	NA	NA	NA
VDY98994.1\|1017723_1018743_+	erythrose 4-phosphate dehydrogenase	NA	NA	NA	NA
VDY98996.1\|1018792_1019956_+	phosphoglycerate kinase	NA	NA	NA	NA
VDY98998.1\|1020170_1021250_+	fructose-bisphosphate aldolase	NA	NA	NA	NA
VDY99000.1\|1021607_1022483_+	mechanosensitive channel MscS	NA	NA	NA	NA
VDY99002.1\|1022524_1023568_-	solute-binding family 7 protein	NA	NA	NA	NA
VDY99004.1\|1023622_1024045_-	Uncharacterised protein	NA	NA	NA	NA
VDY99006.1\|1024034_1024553_-	Uncharacterised protein	NA	NA	NA	NA
VDY99008.1\|1024756_1025392_+	arginine exporter	NA	NA	NA	NA
VDY99010.1\|1025484_1026225_+	oxidative stress defense protein	NA	NA	NA	NA
VDY99012.1\|1026392_1027289_+	DNA-binding transcriptional regulator	NA	NA	NA	NA
VDY99014.1\|1027285_1028764_-	putative acetyl-CoA hydrolase/transferase	NA	NA	NA	NA
VDY99016.1\|1028786_1029572_-	methylmalonyl-CoA decarboxylase	NA	NA	NA	NA
VDY99018.1\|1029582_1030578_-	LAO/AO transport system kinase	NA	NA	NA	NA
VDY99020.1\|1030570_1032715_-	methylmalonyl-CoA mutase	NA	NA	NA	NA
VDY99022.1\|1032918_1033812_-	chromosome initiation inhibitor	NA	NA	NA	NA
VDY99025.1\|1033953_1034151_+	LysR family transcriptional regulator	NA	NA	NA	NA
VDY99027.1\|1034232_1034892_+	ribose-5-phosphate isomerase A	NA	NA	NA	NA
VDY99029.1\|1035147_1036380_+	D-3-phosphoglycerate dehydrogenase	A0A1V0SBV6	Catovirus	1.9e-104	48.4
VDY99031.1\|1036768_1037371_-	5,10-methenyltetrahydrofolate synthetase	NA	NA	NA	NA
VDY99033.1\|1037616_1037946_-	Z-ring-associated protein	NA	NA	NA	NA
VDY99035.1\|1038113_1038692_+	YecA family protein	NA	NA	NA	NA
VDY99037.1\|1038717_1040043_+	proline aminopeptidase II	NA	NA	NA	NA
VDY99039.1\|1040039_1041218_+	2-octaprenyl-6-methoxyphenol hydroxylase	NA	NA	NA	NA
VDY99041.1\|1041240_1042443_+	putative monooxygenase	NA	NA	NA	NA
VDY99043.1\|1042891_1043986_+	aminomethyltransferase (glycine cleavage system protein)	NA	NA	NA	NA
VDY99045.1\|1044009_1044399_+	glycine cleavage system protein H	NA	NA	NA	NA
VDY99047.1\|1044517_1047391_+	glycine dehydrogenase	E3SN07	Prochlorococcus_phage	8.2e-263	52.1
VDY99049.1\|1047554_1048988_-	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	5.1e-32	26.7
VDY99051.1\|1049032_1049344_+	putative cytoplasmic protein	NA	NA	NA	NA
VDY99053.1\|1049507_1050167_+	hemolysin (membrane protein)	NA	NA	NA	NA
VDY99055.1\|1050253_1050775_+\|transposase	transposase	NA	NA	NA	NA
VDY99057.1\|1050999_1051602_+\|transposase	transposase	A0A1B1P773	Bacillus_phage	1.3e-61	56.8

DBSCAN-SWA_4

1242501 : 1249252

uncultured_Mediterranean_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDY99449.1\|1242501_1243263_+	stationary phase survival protein SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.9e-60	48.4
VDY99451.1\|1243256_1243883_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.4e-36	49.7
VDY99453.1\|1244022_1245162_+	lipoprotein NlpD	D7RWE0	Brochothrix_phage	1.7e-06	35.6
VDY99455.1\|1245224_1246217_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.1e-32	37.6
VDY99457.1\|1246336_1246744_-	regulator	NA	NA	NA	NA
VDY99459.1\|1246949_1248491_+\|transposase	transposase for ISEc12	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
VDY99462.1\|1248505_1249252_+\|transposase	transposase	U5N3V8	Enterobacteria_phage	3.5e-24	31.6

DBSCAN-SWA_5

1458803 : 1465283

Escherichia_phage(62.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDY99870.1\|1458803_1459577_-	exodeoxyribonuclease 7 large subunit	A0A1V0SD82	Indivirus	8.4e-13	55.4
VDY99872.1\|1459570_1460173_-	exodeoxyribonuclease 7 large subunit	A0A1V0SC03	Catovirus	1.6e-14	31.4
VDY99874.1\|1460334_1461801_+	inosine 5'-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.3e-88	39.1
VDY99876.1\|1461869_1463447_+	bifunctional GMP synthase/glutamine amidotransferase protein	NA	NA	NA	NA
VDY99878.1\|1463539_1464079_-	Uncharacterised protein	G9L6F0	Escherichia_phage	1.4e-43	98.9
VDY99880.1\|1464094_1464277_-	putative lipoprotein	G9L6F1	Escherichia_phage	1.7e-25	100.0
VDY99882.1\|1464294_1464609_-	putative lipoprotein	G9L6F1	Escherichia_phage	3.9e-33	100.0
VDY99884.1\|1464921_1465113_-	protein	G9L6F2	Escherichia_phage	7.3e-27	100.0
VDY99886.1\|1465130_1465283_+	Uncharacterised protein	G9L6F3	Escherichia_phage	1.7e-18	96.0

DBSCAN-SWA_6

1861269 : 1870714

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ00726.1\|1861269_1862196_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.8e-23	30.8
VDZ00728.1\|1862200_1862932_+	ABC transporter permease	NA	NA	NA	NA
VDZ00730.1\|1862912_1863020_-	putative inner membrane protein	NA	NA	NA	NA
VDZ00732.1\|1863079_1863811_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
VDZ00734.1\|1864032_1865718_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
VDZ00736.1\|1865714_1866434_+	two-component response-regulatory protein YehT	NA	NA	NA	NA
VDZ00738.1\|1866480_1866951_+	conserved protein, DUF1456 family	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
VDZ00740.1\|1866991_1867453_-	lipoprotein yehR	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
VDZ00742.1\|1867577_1869581_-	zinc finger SWIM domain-containing protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.4
VDZ00744.1\|1869577_1870714_-	von Willebrand factor type A domain protein YehP	Q9EYF7	Enterobacteria_phage	3.6e-161	97.1

DBSCAN-SWA_7

2011181 : 2042115

Acidithiobacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ01011.1\|2011181_2011841_-\|transposase	transposase for ISEc12	K4I413	Acidithiobacillus_phage	5.2e-48	45.5
VDZ01013.1\|2012002_2012356_-\|transposase	transposase	K4I413	Acidithiobacillus_phage	1.4e-07	35.4
VDZ01015.1\|2014164_2014473_-	Uncharacterised protein	NA	NA	NA	NA
VDZ01017.1\|2014777_2014924_-\|transposase	putative transposase	NA	NA	NA	NA
VDZ01019.1\|2015333_2015570_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01021.1\|2016718_2017042_+	phospho-2-dehydro-3-deoxyheptonate aldolase	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	3.6e-10	45.9
VDZ01023.1\|2017041_2017752_+	phospho-2-dehydro-3-deoxyheptonate aldolase	A0A0B6VT43	Edwardsiella_phage	1.5e-48	42.4
VDZ01025.1\|2018628_2019483_-\|transposase	transposase insF	U5P429	Shigella_phage	2.8e-49	40.5
VDZ01027.1\|2019553_2019778_-\|transposase	putative transposase	NA	NA	NA	NA
VDZ01029.1\|2020128_2020374_-	Uncharacterised protein	NA	NA	NA	NA
VDZ01031.1\|2020515_2020677_-	Uncharacterised protein	NA	NA	NA	NA
VDZ01033.1\|2020785_2020995_+	microcin H47 immunity protein	NA	NA	NA	NA
VDZ01035.1\|2020945_2021239_+	MchB protein	NA	NA	NA	NA
VDZ01037.1\|2021524_2023075_+	putative microcin H47 biosynthesis protein	NA	NA	NA	NA
VDZ01039.1\|2023100_2023553_+	putative microcin H47 activating protein	NA	NA	NA	NA
VDZ01041.1\|2023686_2024979_+	microcin H47 secretion protein	NA	NA	NA	NA
VDZ01043.1\|2024971_2025373_+	microcin H47 secretion ATP-binding protein	NA	NA	NA	NA
VDZ01045.1\|2025369_2027067_+	microcin H47 secretion ATP-binding protein	F2Y165	Organic_Lake_phycodnavirus	3.4e-14	24.4
VDZ01047.1\|2027102_2027273_+	microcin M imunity protein McmI	NA	NA	NA	NA
VDZ01049.1\|2027771_2028395_-	microcin M activity protein McmM	NA	NA	NA	NA
VDZ01051.1\|2028556_2029015_-	membraneprotein	NA	NA	NA	NA
VDZ01053.1\|2029079_2029271_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01055.1\|2029472_2029985_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01057.1\|2030226_2030796_+	putative DNA-binding protein	NA	NA	NA	NA
VDZ01059.1\|2031070_2031292_-	F1C and S fimbrial switch regulatory protein	NA	NA	NA	NA
VDZ01061.1\|2031709_2032039_+	major pilu subunit operon regulatory protein PapB	NA	NA	NA	NA
VDZ01063.1\|2032211_2032304_-	Uncharacterised protein	NA	NA	NA	NA
VDZ01065.1\|2032410_2032953_+	S fimbrial adhesin major subunit SfaA	NA	NA	NA	NA
VDZ01067.1\|2033115_2033562_+	S fimbriae minor subunit SfaD	NA	NA	NA	NA
VDZ01069.1\|2033602_2034298_+	F1C periplasmic chaperone	NA	NA	NA	NA
VDZ01071.1\|2034367_2036677_+	F1C fimbrial usher	NA	NA	NA	NA
VDZ01073.1\|2036634_2036997_+	C-terminal part of outer membrane F1C fimbrial usher protein SfaF	NA	NA	NA	NA
VDZ01075.1\|2037009_2037537_+	S-fimbrial adhesin protein SfaG	NA	NA	NA	NA
VDZ01077.1\|2037558_2038062_+	S-fimbrial adhesin protein SfaS precursor	NA	NA	NA	NA
VDZ01079.1\|2038006_2039023_+	F1C fimbrial adhesin	NA	NA	NA	NA
VDZ01081.1\|2039326_2040067_+	putative EAL domain-containing protein	NA	NA	NA	NA
VDZ01083.1\|2040347_2040764_+	PapX protein	NA	NA	NA	NA
VDZ01085.1\|2041089_2042115_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2385364 : 2442223

Escherichia_phage(57.63%)

tRNA,lysis,integrase,coat,tail,terminase

attL 2379754:2379768|attR 2420106:2420120

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2379754:2379768	attL	NA	NA	NA	NA
VDZ01848.1\|2385364_2386174_-	putative signaling protein	A0A127AWB9	Bacillus_phage	2.0e-17	39.5
VDZ01850.1\|2386188_2386596_-	Sensory box-containing diguanylate cyclase	NA	NA	NA	NA
VDZ01852.1\|2386850_2387834_+	zinc transport protein	NA	NA	NA	NA
VDZ01854.1\|2388108_2388279_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01856.1\|2388311_2389685_+	ATP-independent RNA helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
VDZ01858.1\|2389813_2390749_-\|tRNA	C32 tRNA thiolase	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
VDZ01860.1\|2390800_2392036_-\|integrase	phage integrase	A0A0U2JGI6	Escherichia_phage	4.6e-239	98.3
VDZ01862.1\|2392037_2392253_-	excisionase	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
VDZ01864.1\|2392331_2392541_-	gydaC	A0A0U2QL97	Escherichia_phage	6.1e-27	98.4
VDZ01866.1\|2392784_2393594_-	recombination and repair protein RecT	A0A1P8DTF2	Proteus_phage	8.8e-106	71.5
VDZ01868.1\|2393586_2396187_-	exonuclease VIII	A0A0U2I1R6	Escherichia_phage	7.9e-249	63.6
VDZ01870.1\|2396317_2396563_-	putative bacteriophage protein	A0A0U2QW85	Escherichia_phage	1.9e-27	80.8
VDZ01872.1\|2396637_2396808_-	Rac prophage; zinc-binding protein	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
VDZ01874.1\|2396807_2397029_-	FtsZ inhibitor protein	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
VDZ01876.1\|2397347_2397959_+	prophage CP-933R superinfection exclusion protein	NA	NA	NA	NA
VDZ01878.1\|2397955_2398111_-	Rac prophage; predicted protein	M4QQ57	Salicola_phage	6.1e-08	55.3
VDZ01880.1\|2398121_2398256_-	Rac prophage protein	NA	NA	NA	NA
VDZ01882.1\|2398564_2399041_-	Rac prophage; putative DNA-binding transcriptional regulator	A0A2D1GNH0	Pseudomonas_phage	2.2e-11	53.4
VDZ01884.1\|2399164_2399461_+	Rac prophage; putative DNA-binding transcriptional regulator	A0A0R6PH31	Moraxella_phage	9.6e-10	44.9
VDZ01886.1\|2399483_2399906_+	Protein of uncharacterised function (DUF1019)	A0A0U2RXZ9	Escherichia_phage	1.5e-69	95.0
VDZ01888.1\|2399919_2400339_+	phage protein	A0A0U2RT81	Escherichia_phage	9.3e-67	94.1
VDZ01890.1\|2400781_2401528_+	putative phage DNA replication protein	V5UQI5	Shigella_phage	8.4e-111	78.5
VDZ01892.1\|2401550_2402312_+	transcription regulatory protein	A0A0U2SAW4	Escherichia_phage	1.7e-114	87.0
VDZ01894.1\|2402327_2402732_+	putative prophage protein	A0A0U2QQN3	Escherichia_phage	2.1e-63	93.3
VDZ01896.1\|2402830_2403988_-	Uncharacterised protein	NA	NA	NA	NA
VDZ01898.1\|2404102_2405281_-	Predicted type IV restriction endonuclease	NA	NA	NA	NA
VDZ01900.1\|2405959_2406559_+	phage protein	A0A0U2RT94	Escherichia_phage	5.5e-105	91.5
VDZ01902.1\|2406558_2406849_+	phage protein	A0A0U2KD41	Escherichia_phage	1.1e-45	86.5
VDZ01904.1\|2406845_2407388_+	antitermination protein	A0A0U2S606	Escherichia_phage	2.9e-76	75.7
VDZ01906.1\|2408432_2408861_+	TolA protein (fragment) of prophage	NA	NA	NA	NA
VDZ01908.1\|2409011_2409407_+	tolA protein (fragment) of prophage	NA	NA	NA	NA
VDZ01910.1\|2409658_2409874_+\|lysis	phage lysis protein	A5LH82	Enterobacteria_phage	5.9e-33	95.8
VDZ01912.1\|2409878_2410223_+	putative prophage protein	K7PGU6	Enterobacteria_phage	1.4e-36	94.0
VDZ01914.1\|2410188_2410461_-	ybl58	NA	NA	NA	NA
VDZ01916.1\|2410566_2411100_+	membrane-associated lysozyme; Qin prophage	K7PLY1	Enterobacteria_phage	4.8e-100	96.0
VDZ01918.1\|2411096_2411561_+\|lysis	lysis protein	A0A0K2FJD0	Enterobacteria_phage	1.7e-69	92.8
VDZ01920.1\|2411731_2413156_+	Rac prophage; potassium transporter subunit	NA	NA	NA	NA
VDZ01922.1\|2413293_2413986_+	ParB-like nuclease	A0A2I7RQE2	Vibrio_phage	4.5e-34	48.1
VDZ01924.1\|2414076_2415009_+	Uncharacterised protein	A0A1B1INP7	uncultured_Mediterranean_phage	2.4e-83	54.5
VDZ01926.1\|2414986_2415196_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01928.1\|2415199_2416294_+\|terminase	terminase small subunit	A0A0U2RXW9	Escherichia_phage	1.0e-112	80.5
VDZ01930.1\|2416274_2416421_+\|terminase	phage terminase	A0A1B1P9C9	Acinetobacter_phage	1.9e-11	71.8
VDZ01932.1\|2416369_2416789_+\|terminase	phage terminase	A0A1B1P9C9	Acinetobacter_phage	3.9e-41	74.0
VDZ01933.1\|2416793_2417273_+\|terminase	phage terminase	A0A2P1MXD8	Escherichia_phage	1.1e-42	59.7
VDZ01935.1\|2417302_2417581_+\|terminase	phage terminase	A0A2P1MXD8	Escherichia_phage	1.2e-14	65.4
VDZ01937.1\|2417573_2417966_+	Uncharacterised protein	G8C7P4	Escherichia_phage	4.8e-49	72.6
VDZ01939.1\|2418046_2418439_+	Uncharacterised protein	G8C7P4	Escherichia_phage	8.2e-33	65.3
VDZ01941.1\|2418559_2418973_+	Uncharacterised protein	G8C7P4	Escherichia_phage	7.8e-42	69.2
VDZ01943.1\|2418953_2419220_+	phage protein	G8C7P5	Escherichia_phage	9.6e-09	54.9
VDZ01945.1\|2419192_2419792_+	phage protein	I6PD76	Cronobacter_phage	1.9e-57	58.1
VDZ01947.1\|2419850_2420069_+	phage protein	G8C7P5	Escherichia_phage	1.8e-13	50.7
VDZ01949.1\|2420169_2420505_+	Uncharacterised protein	G8C7P6	Escherichia_phage	4.4e-19	52.8
2420106:2420120	attR	NA	NA	NA	NA
VDZ01951.1\|2420527_2420932_+	Uncharacterised protein	G8C7P6	Escherichia_phage	9.7e-45	64.7
VDZ01953.1\|2421030_2422170_+\|coat	P22 coat protein - gene protein 5	G8C7P7	Escherichia_phage	7.4e-159	75.0
VDZ01955.1\|2422212_2422389_+	Uncharacterised protein	G8C7P8	Escherichia_phage	4.7e-12	62.3
VDZ01957.1\|2422392_2422788_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01959.1\|2422787_2423171_+	Uncharacterised protein	A0A0P0I456	Acinetobacter_phage	2.2e-14	39.4
VDZ01961.1\|2423171_2423552_+	Uncharacterised protein	A0A059VF88	Pseudomonas_phage	1.1e-18	44.4
VDZ01963.1\|2423548_2423941_+	phage protein	NA	NA	NA	NA
VDZ01965.1\|2423967_2424930_+	Uncharacterised protein	A0A059VG08	Pseudomonas_phage	4.5e-56	39.2
VDZ01967.1\|2424990_2425440_+	Uncharacterised protein	NA	NA	NA	NA
VDZ01969.1\|2425911_2428917_+\|tail	putative phage tail length tape measure protein	A0A1V0E821	Vibrio_phage	1.3e-93	33.7
VDZ01971.1\|2429177_2429381_+\|tail	putative phage minor tail protein	A0A0P0ZDL9	Stx2-converting_phage	5.6e-09	46.2
VDZ01973.1\|2429674_2429986_+\|tail	phage minor tail protein	A0A1B5FP81	Escherichia_phage	8.2e-36	98.7
VDZ01975.1\|2430320_2431064_+\|tail	putative tail fiber component K of prophage	A0A291AWX4	Escherichia_phage	3.6e-106	98.3
VDZ01977.1\|2431338_2431467_+	Tail assembly protein I	A0A2R9YJH6	Escherichia_phage	4.3e-15	100.0
VDZ01979.1\|2431527_2431695_+\|tail	putative phage tail component	A0A291AWT4	Escherichia_phage	1.7e-16	100.0
VDZ01981.1\|2431660_2435008_+	Host specificity protein J of prophage	A0A291AWT4	Escherichia_phage	0.0e+00	90.4
VDZ01983.1\|2435075_2435510_+	membrane protein, Lom/All family	H6WZM8	Escherichia_phage	1.9e-67	90.0
VDZ01985.1\|2435503_2435674_+	Ail/Lom family protein	Q687E7	Enterobacteria_phage	3.0e-24	91.1
VDZ01987.1\|2435738_2436281_+\|tail	putative tail fiber protein	A0A2D1UII2	Escherichia_phage	2.8e-63	98.4
VDZ01989.1\|2436497_2436968_-	Uncharacterised protein	NA	NA	NA	NA
VDZ01991.1\|2437104_2437755_+\|tail	tail fiber protein	A0A1B0VFW4	Salmonella_phage	1.8e-37	54.1
VDZ01994.1\|2438083_2438605_+\|tail	phage side tail fiber protein	X2KTY7	Enterobacteria_phage	8.9e-51	76.0
VDZ01996.1\|2439687_2440545_-	iron/manganese transport system membrane protein SitD	NA	NA	NA	NA
VDZ01999.1\|2440541_2441399_-	iron ABC transporter permease	NA	NA	NA	NA
VDZ02001.1\|2441395_2442223_-	iron ABC transporter ATP-binding protein	M1HV27	Acanthocystis_turfacea_Chlorella_virus	8.7e-08	28.0

DBSCAN-SWA_9

2628721 : 2683644

Enterobacteria_phage(40.82%)

protease,lysis,transposase,integrase,tail,portal,head,terminase

attL 2666384:2666400|attR 2681869:2681885

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ02352.1\|2628721_2630185_-	putative sugar dehydrogenase	H8ZJP8	Ostreococcus_tauri_virus	3.3e-42	29.4
VDZ02354.1\|2630795_2631029_+	Qin prophage DNA-binding transcriptional regulator	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
VDZ02356.1\|2631345_2631936_+	putative DNA-invertase	A0A0A7NPV4	Enterobacteria_phage	1.5e-25	39.3
VDZ02358.1\|2632608_2633841_-\|tail	putative tail fiber protein	K7PHC9	Enterobacteria_phage	2.6e-48	66.9
VDZ02360.1\|2634179_2635070_+	Uncharacterised protein	NA	NA	NA	NA
VDZ02362.1\|2635631_2636231_-	outer membrane precursor Lom	A5LH44	Enterobacteria_phage	1.8e-108	97.0
VDZ02364.1\|2636301_2639715_-\|tail	tail component of prophage CP-933K	K7PKJ2	Enterobacteria_phage	0.0e+00	96.7
VDZ02366.1\|2639775_2640324_-	Tail assembly protein I from prophage	K7PH50	Enterobacteria_phage	1.4e-91	96.2
VDZ02368.1\|2640320_2641064_-\|tail	putative tail fiber component K of prophage	K7PLW1	Enterobacteria_phage	5.9e-149	98.0
VDZ02370.1\|2641068_2641767_-\|tail	phage minor tail protein	A5LH40	Enterobacteria_phage	4.7e-132	98.3
VDZ02372.1\|2641776_2642106_-\|tail	Minor tail protein M	A0A291AWW9	Escherichia_phage	1.7e-60	100.0
VDZ02374.1\|2642105_2644781_-\|tail	putative tail length tape measure protein from putative prophage	A0A291AWX1	Escherichia_phage	0.0e+00	99.6
VDZ02376.1\|2644815_2645172_-\|tail	putative tail length tape measure protein from putative prophage	A0A291AWX1	Escherichia_phage	4.1e-15	100.0
VDZ02378.1\|2645143_2645461_-\|tail	minor tail protein T of prophage	A5LH37	Enterobacteria_phage	1.5e-53	100.0
VDZ02380.1\|2645480_2645867_-\|tail	minor tail component of prophage	A0A291AWW5	Escherichia_phage	1.6e-65	100.0
VDZ02382.1\|2645927_2646671_-\|tail	Major tail protein V	A0A291AWU6	Escherichia_phage	7.8e-133	100.0
VDZ02384.1\|2646681_2647083_-\|tail	Minor tail protein U	A5LH34	Enterobacteria_phage	1.9e-72	99.2
VDZ02386.1\|2647079_2647658_-\|tail	Minor tail protein Z (GPZ) of prophage	A5LH33	Enterobacteria_phage	4.2e-102	100.0
VDZ02388.1\|2647669_2647945_-	prophage protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
VDZ02390.1\|2647937_2648261_-	prophage protein	A0A291AWX2	Escherichia_phage	8.5e-52	100.0
VDZ02392.1\|2648347_2650375_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A291AWT6	Escherichia_phage	0.0e+00	99.7
VDZ02394.1\|2650319_2651828_-\|head,tail,portal	portal protein (head-tail preconnector protein) from prophage	A5LH29	Enterobacteria_phage	8.6e-288	99.4
VDZ02396.1\|2651827_2652040_-	prophage protein	A5LH28	Enterobacteria_phage	7.1e-31	98.6
VDZ02397.1\|2652036_2654136_-\|terminase	terminase large subunit	A5LH27	Enterobacteria_phage	0.0e+00	96.6
VDZ02399.1\|2654144_2654672_-\|terminase	putative terminase small subunit	A5LH26	Enterobacteria_phage	2.1e-92	100.0
VDZ02401.1\|2655056_2655224_+	Uncharacterised protein	NA	NA	NA	NA
VDZ02403.1\|2655244_2655451_-	DLP12 prophage; predicted protein	A0A0K2FJ18	Enterobacteria_phage	6.7e-26	91.2
VDZ02405.1\|2655751_2656162_+	putative envelope protein	C6ZCX4	Enterobacteria_phage	2.1e-63	89.0
VDZ02407.1\|2656313_2656487_-	GnsA/GnsB family transcriptional regulator	NA	NA	NA	NA
VDZ02409.1\|2657736_2658234_-	Qin prophage protein	A0A291LBG9	Klebsiella_phage	3.7e-06	29.5
VDZ02411.1\|2658230_2658764_-	prophage lysozyme (endolysin)	K7PLY1	Enterobacteria_phage	6.4e-97	93.2
VDZ02413.1\|2658760_2659072_-	Qin prophage protein	K7PGU6	Enterobacteria_phage	2.0e-26	64.6
VDZ02415.1\|2659076_2659283_-\|lysis	phage lysis protein	A5LH82	Enterobacteria_phage	4.5e-30	94.1
VDZ02417.1\|2660561_2660774_+	cold shock-like protein CspF	NA	NA	NA	NA
VDZ02419.1\|2661008_2661194_-	Uncharacterised protein	NA	NA	NA	NA
VDZ02421.1\|2661194_2661947_-	lambdoid prophage Qin antitermination protein Q-like protein	A0A192Y5X6	Salmonella_phage	7.1e-134	92.8
VDZ02423.1\|2661960_2662485_-	putative prophage protein	Q8SBE5	Shigella_phage	1.0e-62	69.9
VDZ02425.1\|2662506_2663010_-	putative prophage protein	A0A291AWV9	Escherichia_phage	1.9e-37	45.8
VDZ02427.1\|2663356_2663608_-	putative prophage protein	NA	NA	NA	NA
VDZ02429.1\|2663824_2663980_-	putative host cell-killing modulation protein	A0A0U2QV81	Escherichia_phage	1.5e-17	96.1
VDZ02431.1\|2664051_2664348_-	toxin of the RelE-RelB toxin-antitoxin system	A0A2H4JBF4	uncultured_Caudovirales_phage	9.3e-29	67.8
VDZ02433.1\|2664337_2664577_-	antitoxin of the RelE-RelB toxin-antitoxin system and transcriptional repressor of relBEF	A0A2H4JBG1	uncultured_Caudovirales_phage	1.6e-18	54.4
VDZ02435.1\|2665108_2665441_+	Qin prophage protein	NA	NA	NA	NA
VDZ02437.1\|2665877_2666402_-\|transposase	transposase	NA	NA	NA	NA
VDZ02439.1\|2666358_2666763_-\|transposase	transposase	NA	NA	NA	NA
2666384:2666400	attL	NA	NA	NA	NA
VDZ02441.1\|2666710_2667220_-\|integrase,transposase	putative integrase/transposase	NA	NA	NA	NA
VDZ02443.1\|2667253_2667673_-	exclusion protein	A0A0U2QQN3	Escherichia_phage	1.3e-55	93.4
VDZ02445.1\|2667713_2668679_-	ybl78	U5P0A0	Shigella_phage	1.7e-55	61.2
VDZ02447.1\|2668659_2669181_-	YdfX	NA	NA	NA	NA
VDZ02449.1\|2669184_2669391_-	DNA-binding transcriptional regulator DicC	NA	NA	NA	NA
VDZ02451.1\|2669417_2669876_+	transcriptional repressor DicA	I6PD69	Cronobacter_phage	2.8e-24	46.2
VDZ02453.1\|2670068_2670221_+	ydfA	M4QQ57	Salicola_phage	2.3e-07	52.1
VDZ02455.1\|2670226_2670478_+	putative prophage protein	NA	NA	NA	NA
VDZ02457.1\|2671289_2671478_+	division inhibition protein	NA	NA	NA	NA
VDZ02459.1\|2671474_2671666_+	putative prophage protein	NA	NA	NA	NA
VDZ02461.1\|2671759_2674231_+	putative exonuclease from phage origin	A0A192Y6E0	Salmonella_phage	8.5e-59	56.7
VDZ02463.1\|2674318_2674555_+	putative excisionase	S4TND0	Salmonella_phage	6.1e-15	50.7
VDZ02465.1\|2674589_2674718_+\|integrase	defective integrase; Qin prophage	S4TSP2	Salmonella_phage	1.3e-11	80.6
VDZ02467.1\|2675074_2675563_+\|integrase	defective integrase; Qin prophage	Q859D2	Escherichia_coli_phage	1.9e-55	62.0
VDZ02469.1\|2675604_2675868_+\|integrase	C-terminus fragment integrase	A0A286S1S8	Klebsiella_phage	2.6e-30	72.2
VDZ02471.1\|2675887_2675998_-	protein, truncated	NA	NA	NA	NA
VDZ02473.1\|2676055_2676304_-	dehydrogenase	NA	NA	NA	NA
VDZ02475.1\|2676487_2676985_-	dehydrogenase	E3SJ82	Synechococcus_phage	3.4e-07	28.3
VDZ02477.1\|2677085_2677754_-	starvation sensing protein RspA	NA	NA	NA	NA
VDZ02479.1\|2677896_2678142_-	starvation sensing protein RspA	Q6A202	Oenococcus_phage	8.5e-12	48.5
VDZ02481.1\|2678526_2678823_-	inner membrane protein	A0A218MNG8	uncultured_virus	4.5e-23	55.8
VDZ02483.1\|2678950_2679298_+	protein	NA	NA	NA	NA
VDZ02485.1\|2679332_2679566_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
VDZ02487.1\|2679522_2679771_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
VDZ02489.1\|2679770_2679893_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
VDZ02491.1\|2679895_2680642_-	lipoprotein	NA	NA	NA	NA
VDZ02493.1\|2680713_2681019_+	protein	NA	NA	NA	NA
VDZ02495.1\|2681217_2683644_+	putative dimethyl sulfoxide reductase, oxidoreductase subunit	A0A077SK27	Escherichia_phage	1.7e-213	49.1
2681869:2681885	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3067821 : 3132579

Escherichia_phage(51.28%)

protease,integrase,transposase,tail,portal,head,terminase,capsid

attL 3085474:3085489|attR 3115304:3115319

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ03388.1\|3067821_3068070_-\|tail	Qin prophage; side tail fiber assembly protein	NA	NA	NA	NA
VDZ03390.1\|3068066_3071222_-\|tail	phage tail domain-containing protein	X2KTY7	Enterobacteria_phage	1.7e-11	35.5
VDZ03392.1\|3071286_3071886_-	membrane protein, Lom/All family	H6WZM8	Escherichia_phage	7.7e-107	95.5
VDZ03394.1\|3072114_3075432_-	Host specificity protein J of prophage	A0A291AWT4	Escherichia_phage	0.0e+00	93.1
VDZ03396.1\|3075492_3076041_-	Tail assembly protein I from prophage	K7PH50	Enterobacteria_phage	1.4e-91	96.2
VDZ03398.1\|3076037_3076637_-\|tail	tail component	K7PLW1	Enterobacteria_phage	1.4e-119	98.5
VDZ03400.1\|3076785_3077484_-\|tail	phage minor tail protein	A0A1B5FP81	Escherichia_phage	4.4e-130	96.6
VDZ03402.1\|3077483_3077825_-\|tail	prophage minor tail protein	A0A0P0ZDL9	Stx2-converting_phage	1.2e-40	66.4
VDZ03404.1\|3077817_3080628_-\|tail	phage-related minor tail protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	94.4
VDZ03406.1\|3080591_3081044_-\|tail	phage-related minor tail protein	A0A1B5FPE2	Escherichia_phage	1.3e-58	99.2
VDZ03408.1\|3081090_3081369_-	prophage protein	A0A1B5FP87	Escherichia_phage	3.6e-43	97.8
VDZ03409.1\|3081392_3081764_-\|tail	tail assembly chaperone	A0A1B5FP91	Escherichia_phage	6.5e-64	100.0
VDZ03411.1\|3082073_3082532_-\|tail	phage major tail subunit	A0A1B5FP82	Escherichia_phage	1.1e-31	93.6
VDZ03414.1\|3082540_3082885_-	putative prophage protein	A0A1B5FP84	Escherichia_phage	4.2e-57	100.0
VDZ03416.1\|3082881_3083328_-	prophage protein	S4TR46	Salmonella_phage	2.3e-63	80.4
VDZ03418.1\|3083327_3083666_-\|head,tail	putative prophage head-tail adaptor	A0A1B5FP90	Escherichia_phage	1.6e-56	99.1
VDZ03420.1\|3083674_3083980_-	phage protein	A0A1B5FP86	Escherichia_phage	9.2e-40	100.0
VDZ03422.1\|3083991_3084180_-	phage protein	A0A1B5FP98	Escherichia_phage	7.2e-27	100.0
VDZ03424.1\|3084230_3085436_-\|capsid	major capsid protein	A0A1B5FPI9	Escherichia_phage	1.0e-222	99.3
VDZ03426.1\|3085450_3086101_-\|head,protease	pro-head protease	U5P4H2	Shigella_phage	2.5e-119	100.0
3085474:3085489	attL	NA	NA	NA	NA
VDZ03428.1\|3086078_3087320_-\|portal	phage portal protein	U5P411	Shigella_phage	2.0e-242	99.8
VDZ03430.1\|3087319_3087502_-	prophage protein	A0A1B5FP99	Escherichia_phage	2.5e-24	95.0
VDZ03432.1\|3087513_3089271_-\|terminase	phage terminase	A0A1B5FP96	Escherichia_phage	0.0e+00	99.7
VDZ03434.1\|3089431_3089752_-\|terminase	putative prophage terminase, small subunit	A0A1B5FPA0	Escherichia_phage	6.2e-47	97.9
VDZ03436.1\|3089899_3090250_-	putative prophage endonuclease	A0A1B5FP94	Escherichia_phage	1.2e-64	98.3
VDZ03438.1\|3090292_3090760_-	endopeptidase	A0A1B5FPA1	Escherichia_phage	7.7e-70	91.6
VDZ03440.1\|3090756_3091290_-	membrane-associated lysozyme; Qin prophage	Q08J98	Stx2-converting_phage	3.6e-100	94.4
VDZ03442.1\|3091353_3091704_-	putative prophage protein	K7PGU6	Enterobacteria_phage	2.9e-37	95.2
VDZ03444.1\|3091708_3091924_-	Lysis protein S	M1FN85	Enterobacteria_phage	5.3e-34	98.6
VDZ03446.1\|3092736_3093426_-	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.8e-59	50.6
VDZ03448.1\|3093422_3093788_-	Holliday junction resolvase	V5URS4	Shigella_phage	1.6e-38	66.7
VDZ03450.1\|3093788_3094058_-	phage protein	U5P0K4	Shigella_phage	3.8e-29	70.7
VDZ03452.1\|3094201_3094846_-	phage protein	S5FV02	Shigella_phage	5.7e-47	45.5
VDZ03454.1\|3095224_3095443_-	putative prophage protein	NA	NA	NA	NA
VDZ03456.1\|3096554_3097250_+	e14 prophage; predicted inner membrane protein	NA	NA	NA	NA
VDZ03458.1\|3097262_3097916_+	S-adenosyl-L-methionine-dependent methyltransferases	NA	NA	NA	NA
VDZ03460.1\|3098230_3099130_-	Uncharacterised protein	NA	NA	NA	NA
VDZ03462.1\|3099382_3099805_-	phage protein	A0A0U2QQN3	Escherichia_phage	4.8e-63	91.8
VDZ03464.1\|3099845_3100811_-	ybl78	U5P0A0	Shigella_phage	2.6e-56	60.8
VDZ03466.1\|3100791_3101313_-	YdfX	NA	NA	NA	NA
VDZ03468.1\|3101296_3101524_-	DNA-binding transcriptional regulator DicC	NA	NA	NA	NA
VDZ03470.1\|3101604_3102012_+	transcriptional repressor DicA	I6PD69	Cronobacter_phage	1.6e-31	51.9
VDZ03472.1\|3102180_3102336_+	putative prophage protein	M4QQ57	Salicola_phage	3.0e-07	53.2
VDZ03474.1\|3102337_3102460_+	putative prophage protein	NA	NA	NA	NA
VDZ03476.1\|3102717_3102882_-	Uncharacterised protein	NA	NA	NA	NA
VDZ03478.1\|3103281_3103470_+	division inhibition protein dicB	NA	NA	NA	NA
VDZ03480.1\|3103466_3103658_+	putative prophage protein	NA	NA	NA	NA
VDZ03482.1\|3103891_3106192_+	Exodeoxyribonuclease VIII from bacteriophage origin	A0A0U2I1R6	Escherichia_phage	2.1e-99	47.5
VDZ03484.1\|3106250_3106454_+	putative prophage protein	NA	NA	NA	NA
VDZ03486.1\|3106453_3107479_+\|integrase	site-specific recombinase, phage integrase family	A0A192Y7M7	Salmonella_phage	3.4e-102	57.9
VDZ03488.1\|3107713_3108148_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
VDZ03490.1\|3108808_3108958_+	Uncharacterised protein	NA	NA	NA	NA
VDZ03492.1\|3108971_3110960_+	adhesin	NA	NA	NA	NA
VDZ03494.1\|3110956_3111418_+	putative invasin	NA	NA	NA	NA
VDZ03496.1\|3111468_3116766_+	putative invasin	NA	NA	NA	NA
3115304:3115319	attR	NA	NA	NA	NA
VDZ03498.1\|3117520_3118291_-	ADP-heptose--LPS heptosyltransferase-like protein	NA	NA	NA	NA
VDZ03500.1\|3118605_3119922_+	shikimate transporter	NA	NA	NA	NA
VDZ03502.1\|3120023_3120851_+	AMP nucleosidase	NA	NA	NA	NA
VDZ03504.1\|3120847_3121477_+	AMP nucleosidase	NA	NA	NA	NA
VDZ03506.1\|3121819_3122536_+	putative cytoplasmic protein	NA	NA	NA	NA
VDZ03508.1\|3123163_3124618_-	multidrug efflux system	NA	NA	NA	NA
VDZ03510.1\|3124924_3125875_-	LysR family transcriptional regulator	NA	NA	NA	NA
VDZ03512.1\|3125976_3126894_-	Nitrogen assimilation regulatory protein nac	NA	NA	NA	NA
VDZ03514.1\|3127351_3128287_-	ErfK/YbiS/YcfS/YnhG family protein	NA	NA	NA	NA
VDZ03516.1\|3128348_3129428_-	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	NA	NA	NA	NA
VDZ03518.1\|3129439_3130183_-	cobalamin synthase	NA	NA	NA	NA
VDZ03520.1\|3130179_3130725_-	bifunctional adenosylcobalamin biosynthesis protein [includes adenosylcobinamide kinase; adenosylcobinamide-phosphate guanylyltransferase]	NA	NA	NA	NA
VDZ03522.1\|3132462_3132579_+\|transposase	putative transposase, ISEc23	A0A0P0ZBS5	Stx2-converting_phage	1.2e-08	71.4

DBSCAN-SWA_11

3137408 : 3153311

Escherichia_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ03538.1\|3137408_3138788_-\|transposase	transposase	NA	NA	NA	NA
VDZ03540.1\|3139071_3139482_-	DNA-directed RNA polymerase, beta subunit/140 kD subunit	NA	NA	NA	NA
VDZ03542.1\|3139469_3139871_-	ybl85	NA	NA	NA	NA
VDZ03544.1\|3140130_3140652_-	malate transporter	NA	NA	NA	NA
VDZ03546.1\|3142213_3142366_+	InterPro motifs Prophage CP4-57 regulatory protein (AlpA)	NA	NA	NA	NA
VDZ03548.1\|3142511_3142712_+	Uncharacterised protein	NA	NA	NA	NA
VDZ03550.1\|3142651_3143098_+	Uncharacterised protein	NA	NA	NA	NA
VDZ03552.1\|3144039_3144819_-	insertion sequence IS100, ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.5e-139	100.0
VDZ03554.1\|3144818_3145841_-\|transposase	transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
VDZ03556.1\|3147460_3148612_+	Uncharacterised protein	NA	NA	NA	NA
VDZ03558.1\|3148695_3148923_+	putative GTP-binding protein	NA	NA	NA	NA
VDZ03560.1\|3149101_3150358_+\|transposase	transposase for ISEc12	K4I413	Acidithiobacillus_phage	6.0e-101	47.8
VDZ03562.1\|3150656_3151403_+\|transposase	transposase	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
VDZ03564.1\|3151493_3151697_-	putative exonuclease family protein	NA	NA	NA	NA
VDZ03566.1\|3152035_3152767_+\|transposase	putative transposase	NA	NA	NA	NA
VDZ03568.1\|3152747_3153311_+\|transposase	putative transposase	NA	NA	NA	NA

DBSCAN-SWA_12

3380862 : 3391774

Escherichia_phage(42.86%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ04025.1\|3380862_3381114_-	anaerobic dimethyl sulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	3.4e-24	61.4
VDZ04027.1\|3381659_3381920_-	anaerobic dimethyl sulfoxide reductase chain A	NA	NA	NA	NA
VDZ04029.1\|3381999_3382290_-	anaerobic dimethyl sulfoxide reductase chain A	NA	NA	NA	NA
VDZ04031.1\|3382378_3382882_-	anaerobic dimethyl sulfoxide reductase chain A	A0A077SK27	Escherichia_phage	6.6e-43	51.5
VDZ04033.1\|3383011_3383923_-	anaerobic dimethyl sulfoxide reductase chain A	A0A077SK27	Escherichia_phage	3.6e-63	49.6
VDZ04035.1\|3384161_3384347_-\|tRNA	seryl-tRNA synthetase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.1e-11	59.3
VDZ04037.1\|3384289_3385453_-\|tRNA	seryl-tRNA synthetase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.6e-58	43.1
VDZ04039.1\|3385543_3386887_-	putative ATPase	G3MBE0	Bacillus_virus	2.1e-80	40.8
VDZ04041.1\|3386897_3387509_-	outer-membrane lipoprotein carrier protein	NA	NA	NA	NA
VDZ04043.1\|3387667_3391774_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.2e-86	48.7

DBSCAN-SWA_13

3756854 : 3817584

Enterobacteria_phage(62.9%)

protease,lysis,transposase,coat,tail,portal,integrase,head,terminase,capsid

attL 3756386:3756432|attR 3818155:3818201

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3756386:3756432	attL	NA	NA	NA	NA
VDZ04733.1\|3756854_3757808_+\|protease	outer membrane protease	NA	NA	NA	NA
VDZ04734.1\|3757994_3759479_+\|protease	putative protease	NA	NA	NA	NA
VDZ04735.1\|3760036_3760693_+	methylase	NA	NA	NA	NA
VDZ04736.1\|3761396_3762938_+\|transposase	transposase for ISEc12	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
VDZ04737.1\|3762952_3763699_+\|transposase	transposase	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
VDZ04738.1\|3763752_3763917_-\|tail	tail fiber chaperone; Qin prophage	K7PMH7	Enterobacteria_phage	8.2e-19	97.8
VDZ04739.1\|3763916_3766877_-\|tail	putative tail fiber protein	A0A2D1UII2	Escherichia_phage	3.0e-58	98.3
VDZ04740.1\|3766941_3767541_-	outer membrane precursor Lom	A0A0P0ZCF6	Stx2-converting_phage	1.8e-108	97.5
VDZ04741.1\|3767611_3770368_-\|tail	tail component of prophage CP-933K	K7PKJ2	Enterobacteria_phage	0.0e+00	96.6
VDZ04742.1\|3770321_3771026_-\|tail	tail component of prophage	K7PKJ2	Enterobacteria_phage	7.2e-96	98.3
VDZ04743.1\|3771097_3771658_-\|tail	phage tail assembly protein	A0A0K2FJB0	Escherichia_phage	6.8e-65	94.6
VDZ04744.1\|3771654_3772398_-\|tail	putative tail fiber component K of prophage	K7PLW1	Enterobacteria_phage	2.5e-147	96.8
VDZ04745.1\|3772403_3773102_-\|tail	phage minor tail protein	A0A0K2FJ01	Enterobacteria_phage	7.3e-133	99.1
VDZ04746.1\|3773101_3773431_-\|tail	Minor tail protein M	A0A0K2FIE9	Enterobacteria_phage	3.6e-58	99.1
VDZ04747.1\|3773427_3775989_-\|tail	tail component of prophage	A0A0K2FI43	Enterobacteria_phage	0.0e+00	92.6
VDZ04748.1\|3775981_3776416_-\|tail	minor tail protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
VDZ04749.1\|3776397_3776820_-\|tail	phage minor tail protein	A0A0K2FIQ8	Enterobacteria_phage	3.1e-70	96.4
VDZ04750.1\|3776835_3777576_-\|tail	Major tail protein V	A0A0K2FJ05	Enterobacteria_phage	1.0e-129	98.0
VDZ04751.1\|3777583_3777979_-\|tail	phage minor tail protein	A0A0K2FIF4	Enterobacteria_phage	2.9e-70	99.2
VDZ04752.1\|3777975_3778554_-\|tail	Minor tail protein Z (GpZ)	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
VDZ04753.1\|3778544_3778919_-\|capsid	minor capsid protein	A0A2R9YJJ5	Escherichia_phage	8.0e-62	99.1
VDZ04754.1\|3778930_3779326_-	DNA packaging protein from bacteriophage origin	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
VDZ04755.1\|3779367_3780393_-\|head,coat	phage major head protein (major coat protein)	C6ZCY2	Enterobacteria_phage	1.8e-188	97.7
VDZ04756.1\|3780448_3780781_-	Head decoration protein from bacteriophage origin	A0A2R9YJN3	Escherichia_phage	5.0e-55	99.1
VDZ04757.1\|3780890_3782111_-\|capsid	minor capsid protein C from bacteriophage origin	A0A0K2FI53	Enterobacteria_phage	9.3e-200	96.9
VDZ04758.1\|3782091_3782865_-\|capsid,portal	phage portal protein (minor capsid protein)	A0A0K2FJC0	Enterobacteria_phage	8.9e-140	98.8
VDZ04759.1\|3783679_3783961_-	putative prophage protein	NA	NA	NA	NA
VDZ04760.1\|3783972_3784515_-	gp1	O64316	Escherichia_phage	3.4e-37	48.8
VDZ04761.1\|3784716_3785100_-	putative transcriptional regulator	NA	NA	NA	NA
VDZ04762.1\|3785111_3785453_-\|head	putative head decoration protein from prophage	NA	NA	NA	NA
VDZ04763.1\|3785462_3786503_-\|head	putative major head protein from prophage	C6ZCY2	Enterobacteria_phage	3.0e-66	42.2
VDZ04764.1\|3786720_3787143_-	putative prophage single-stranded DNA binding protein	NA	NA	NA	NA
VDZ04765.1\|3787139_3787397_-	putative prophage protein	NA	NA	NA	NA
VDZ04766.1\|3787686_3788568_-	nucleic acid independent nucleoside triphosphatase; phage DNA primase	Q7M2A8	Enterobacteria_phage	9.1e-64	45.6
VDZ04767.1\|3788564_3789332_-	nucleic acid independent nucleoside triphosphatase; phage DNA primase	NA	NA	NA	NA
VDZ04768.1\|3789467_3789731_-	putative prophage protein	NA	NA	NA	NA
VDZ04769.1\|3789748_3789970_-	Uncharacterised protein	NA	NA	NA	NA
VDZ04770.1\|3789966_3790161_-	Uncharacterised protein	A0A286S1P8	Klebsiella_phage	1.1e-11	59.3
VDZ04771.1\|3790160_3790346_-	putative prophage protein	NA	NA	NA	NA
VDZ04772.1\|3790338_3790536_-	putative prophage protein	NA	NA	NA	NA
VDZ04773.1\|3790725_3791031_+	Uncharacterised protein	NA	NA	NA	NA
VDZ04774.1\|3791164_3791680_-	putative prophage antirepressor	A0A1W6JPH8	Morganella_phage	1.7e-14	44.9
VDZ04775.1\|3791987_3792245_-	putative DNA binding protein from phage origin	NA	NA	NA	NA
VDZ04776.1\|3792246_3792432_-\|integrase	putative integrase of prophage	NA	NA	NA	NA
VDZ04777.1\|3793201_3793483_-\|integrase	putative integrase of prophage	NA	NA	NA	NA
VDZ04778.1\|3793747_3794713_-\|capsid,portal	phage portal protein (minor capsid protein)	A0A0K2FJC0	Enterobacteria_phage	6.6e-124	84.9
VDZ04779.1\|3794709_3796632_-\|terminase	terminase GpA	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	93.0
VDZ04780.1\|3796606_3797152_-	prophage qsr' DNA packaging protein NU1-like protein	A0A0K2FIG2	Enterobacteria_phage	4.0e-94	98.3
VDZ04781.1\|3798094_3798388_+	lambdoid prophage DLP12 Bor-like protein	K7PL54	Enterobacteria_phage	2.0e-44	91.8
VDZ04782.1\|3798478_3798880_-	Rz endopeptidase from lambdoid prophage DLP12	A0A0K2FJD0	Enterobacteria_phage	1.6e-55	99.1
VDZ04783.1\|3798876_3799374_-	phage lysozome	M1FJA0	Enterobacteria_phage	1.1e-90	97.6
VDZ04784.1\|3799373_3799589_-\|lysis	phage lysis protein	A5LH82	Enterobacteria_phage	9.0e-34	100.0
VDZ04785.1\|3800176_3801274_+	outer membrane porin; DLP12 prophage	Q1MVN1	Enterobacteria_phage	4.8e-155	76.3
VDZ04786.1\|3801462_3801846_-	lambdoid prophage DLP12 antitermination protein Q	A0A088CD47	Shigella_phage	4.4e-55	83.3
VDZ04787.1\|3801931_3802069_-	DLP12 prophage; small protein	K7PHH3	Enterobacteria_phage	2.4e-08	70.7
VDZ04788.1\|3802068_3802431_-	endodeoxyribonuclease RUS	K7PM48	Enterobacteria_phage	4.3e-60	96.5
VDZ04789.1\|3802427_3802718_-	DLP12 prophage	K7PGZ6	Enterobacteria_phage	4.3e-47	94.8
VDZ04790.1\|3802710_3802881_-	prophage protein NinE	K7P7K0	Enterobacteria_phage	1.5e-12	67.9
VDZ04791.1\|3802880_3803336_-	DLP12 prophage; DNA base-flipping protein	I6PD71	Cronobacter_phage	1.1e-60	67.5
VDZ04792.1\|3803547_3803928_-	DNA-binding transcriptional regulator; DLP12 prophage	NA	NA	NA	NA
VDZ04793.1\|3803999_3804344_-	DNA-binding transcriptional regulator; DLP12 prophage	NA	NA	NA	NA
VDZ04794.1\|3804353_3804905_-	kinase inhibitor	NA	NA	NA	NA
VDZ04795.1\|3805369_3806896_-	site-specific invertase; DLP12 prophage	Q3HQV4	Burkholderia_phage	7.9e-31	27.8
VDZ04796.1\|3807152_3807485_-	Multidrug transporter emrE	NA	NA	NA	NA
VDZ04797.1\|3807552_3807855_-	Ren protein from phage origin	A0A0N6WES4	Escherichia_phage	1.1e-42	95.7
VDZ04798.1\|3807851_3808553_-	replication protein P of bacteriophage	M1FJ72	Enterobacteria_phage	1.4e-128	98.7
VDZ04799.1\|3808661_3808922_-	replication protein O of prophage CP-933X	A0A1I9LJP3	Stx_converting_phage	5.4e-41	98.7
VDZ04800.1\|3808918_3809299_-	replication protein O of prophage CP-933X	NA	NA	NA	NA
VDZ04801.1\|3809267_3809417_-	replication protein O	A0A075B8J2	Enterobacteria_phage	1.8e-12	77.8
VDZ04802.1\|3809359_3809569_-	replication protein O	NA	NA	NA	NA
VDZ04803.1\|3809565_3809946_-	bacteriophage regulatory protein CII	K7PJT7	Enterobacteria_phage	3.0e-40	73.3
VDZ04804.1\|3809902_3810106_-	bacteriophage regulatory protein CII	M9NZI6	Enterobacteria_phage	5.6e-17	64.7
VDZ04805.1\|3810136_3810364_-	represror Cro	Q76H55	Enterobacteria_phage	3.8e-22	69.0
VDZ04806.1\|3810681_3811167_+	Regulatory protein CI from bacteriophage origin	Q76H56	Enterobacteria_phage	7.0e-74	90.4
VDZ04807.1\|3811273_3811438_+	Uncharacterised protein	A0A1S5SA14	Streptococcus_phage	2.0e-09	63.8
VDZ04808.1\|3812528_3812867_+	Uncharacterised protein	NA	NA	NA	NA
VDZ04809.1\|3813454_3813661_+	prophage Kil protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
VDZ04810.1\|3813737_3814034_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
VDZ04811.1\|3814039_3814825_+	bacteriophage recombination protein	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
VDZ04812.1\|3814821_3815214_+	exonuclease	A0A0P0ZCD4	Stx2-converting_phage	9.0e-56	99.0
VDZ04813.1\|3815407_3815503_+	DLP12 prophage; exonuclease	A0A0N6WET1	Escherichia_phage	1.8e-10	100.0
VDZ04814.1\|3815499_3815607_+	phage protein	A0A1U8QQC1	Enterobacteria_phage	3.3e-05	81.5
VDZ04815.1\|3815653_3815845_+	phage protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
VDZ04816.1\|3816139_3816343_+	Uncharacterised protein	M1FQW7	Enterobacteria_phage	2.9e-05	100.0
VDZ04817.1\|3816499_3816856_+	bacteriophage protein	M1FPC8	Enterobacteria_phage	7.7e-46	97.8
VDZ04818.1\|3816978_3817584_+\|integrase	site-specific recombinase, phage integrase family protein	A0A088CD23	Shigella_phage	7.6e-86	79.8
3818155:3818201	attR	NA	NA	NA	NA

DBSCAN-SWA_14

3995562 : 4005520

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ04974.1\|3995562_3996615_-	phosphate regulon two-component system, sensor kinase	W8CYF6	Bacillus_phage	1.3e-27	31.2
VDZ04975.1\|3996569_3996857_-	phosphate regulon two-component system, sensor kinase	NA	NA	NA	NA
VDZ04976.1\|3996914_3997604_-	phosphate regulon two-component system, response regulator	W8CYM9	Bacillus_phage	4.4e-37	38.0
VDZ04977.1\|3997793_3998996_+	exonuclease SbcD	R4JGS2	Bacillus_phage	4.8e-07	24.1
VDZ04978.1\|3998992_4002136_+	exonuclease, dsDNA, ATP-dependent	G3MAB6	Bacillus_virus	5.8e-12	26.9
VDZ04979.1\|4002176_4003556_+	MFS transporter AraJ	NA	NA	NA	NA
VDZ04980.1\|4003577_4004486_-	fructokinase	NA	NA	NA	NA
VDZ04981.1\|4004543_4004846_+	exonuclease RdgC	A0A067ZG66	Vibrio_phage	1.0e-11	44.3
VDZ04982.1\|4004842_4005520_+	exonuclease RdgC	S4TWL4	Salmonella_phage	5.7e-82	69.3

DBSCAN-SWA_15

4052709 : 4056992

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ05033.1\|4052709_4052907_+	lactose operon repressor	C6ZCU4	Enterobacteria_phage	8.3e-18	95.9
VDZ05034.1\|4053007_4053421_+	lactose operon repressor	C6ZCU4	Enterobacteria_phage	1.7e-52	99.1
VDZ05035.1\|4053383_4053755_+	lactose operon repressor	C6ZCU4	Enterobacteria_phage	2.1e-46	86.3
VDZ05036.1\|4053920_4054091_+	beta-galactosidase	Q37953	Phage_M13mp18	6.1e-17	93.2
VDZ05037.1\|4054700_4054985_+	beta-D-galactosidase	L0N6M2	Herpes_simplex_virus	9.8e-44	97.8
VDZ05038.1\|4055033_4056992_+	beta-D-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.8

DBSCAN-SWA_16

4566989 : 4585617

Stx2-converting_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ05565.1\|4566989_4568531_+\|transposase	transposase for ISEc12	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
VDZ05566.1\|4568545_4569292_+\|transposase	transposase	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
VDZ05567.1\|4569349_4570429_-	CP4-44 prophage; antigen 43 (Ag43)phase-variable biofilm formation autotransporter	NA	NA	NA	NA
VDZ05568.1\|4570392_4571202_-	antigen 43, truncation	NA	NA	NA	NA
VDZ05569.1\|4571573_4572446_-	putative GTP-binding protein	NA	NA	NA	NA
VDZ05570.1\|4573674_4575159_+	CP4-57 prophage protein	NA	NA	NA	NA
VDZ05571.1\|4575480_4576083_-	Uncharacterised protein	NA	NA	NA	NA
VDZ05572.1\|4576177_4576384_-	regulatory protein	NA	NA	NA	NA
VDZ05573.1\|4577507_4577708_-	Uncharacterised protein	NA	NA	NA	NA
VDZ05574.1\|4577907_4578477_+	malate transporter	NA	NA	NA	NA
VDZ05575.1\|4578736_4579138_+	ybl85	NA	NA	NA	NA
VDZ05576.1\|4579125_4579245_+	Uncharacterised protein	NA	NA	NA	NA
VDZ05577.1\|4579295_4579559_+	Protein of uncharacterised function (DUF3279)	NA	NA	NA	NA
VDZ05578.1\|4579558_4579795_+	Uncharacterised protein	NA	NA	NA	NA
VDZ05579.1\|4580288_4580390_+	IS orf	A0A0P0ZBY2	Stx2-converting_phage	1.5e-10	100.0
VDZ05580.1\|4580401_4580635_+\|transposase	transposase	A0A0P0ZBY2	Stx2-converting_phage	3.8e-38	100.0
VDZ05581.1\|4580728_4581007_+	IS encoded protein within CP-933O	A0A0P0ZBS5	Stx2-converting_phage	1.7e-40	95.7
VDZ05582.1\|4581156_4581654_+\|transposase	transposase	A0A0P0ZBS5	Stx2-converting_phage	1.0e-56	98.2
VDZ05583.1\|4581783_4581930_+\|transposase	transposase	A0A0P0ZBS5	Stx2-converting_phage	4.3e-11	47.5
VDZ05584.1\|4582297_4582717_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VDZ05585.1\|4582704_4582842_-	Uncharacterised protein	NA	NA	NA	NA
VDZ05586.1\|4582871_4583240_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VDZ05587.1\|4583480_4583648_-	Uncharacterised protein	NA	NA	NA	NA
VDZ05588.1\|4585407_4585617_-\|transposase	IS1 transposase	U5P0U6	Shigella_phage	2.2e-32	98.6

DBSCAN-SWA_17

4592736 : 4600055

Shigella_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ05597.1\|4592736_4593168_+	Iron(III) dicitrate transport system permease protein fecD	A0A2H4IY97	uncultured_Caudovirales_phage	5.9e-08	29.1
VDZ05598.1\|4593168_4593927_+	iron(III) dicitrate transport system, ATP-binding protein	G3M9Y6	Bacillus_virus	6.3e-13	24.8
VDZ05599.1\|4594491_4594749_-	KpLE2 phage-like element	NA	NA	NA	NA
VDZ05600.1\|4594831_4595485_-\|transposase	putative transposase subunit	Q716C2	Shigella_phage	1.7e-128	99.1
VDZ05601.1\|4595683_4595986_+	IS600 ORF1-like protein	NA	NA	NA	NA
VDZ05602.1\|4596021_4596840_+\|transposase	IS600 orfAB' transposase	A0A0P0I4A4	Acinetobacter_phage	1.2e-65	45.2
VDZ05603.1\|4596993_4598991_+	secondary glycine betaine transporter	A0A2I7QNT1	Vibrio_phage	7.4e-21	25.9
VDZ05604.1\|4598935_4599094_+	Uncharacterised protein	NA	NA	NA	NA
VDZ05605.1\|4599053_4599467_+	Predicted membrane protein (DUF2254)	NA	NA	NA	NA
VDZ05606.1\|4599401_4600055_-\|transposase	putative transposase subunit	Q716C2	Shigella_phage	1.1e-130	99.5

DBSCAN-SWA_18

5156988 : 5162317

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ06165.1\|5156988_5157438_-	dTDP-4-oxo-6-deoxy-D-glucose transaminase	A0A0F7LAY0	uncultured_marine_virus	6.2e-08	46.5
VDZ06166.1\|5157442_5158117_-	TDP-fucosamine acetyltransferase	NA	NA	NA	NA
VDZ06167.1\|5158094_5158976_-	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	8.7e-107	66.3
VDZ06168.1\|5158994_5159453_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.1e-36	50.4
VDZ06169.1\|5159427_5160063_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.7e-54	55.0
VDZ06170.1\|5160062_5161325_-	UDP-N-acetyl-D-mannosamine dehydrogenase	M1HNJ7	Paramecium_bursaria_Chlorella_virus	1.0e-23	27.0
VDZ06171.1\|5161321_5162317_-	UDP-N-acetylglucosamine 2-epimerase	A0A1V0SAG5	Catovirus	3.5e-27	31.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134081

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection