CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134090	Staphylococcus aureus strain NCTC9555 genome assembly, chromosome: 1	9 crisprs	cas3,csa3,DinG,DEDDh,WYL	7	2	12	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134090_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_1

735671-735770

Orphan

Consensus_repeat	Method
AAGATCCCCTAATTAATAAATTAAAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_1

>merge|LR134090|1|735671-735770|CRISPRCasFinder
AAGATCCCCTAATTAATAAATTAAAAGGGGACTAAAGGAATACAGTTGATTGCTAATGCACCAACAGCAAAAGAGCCCCTAATTAATAAATTAAAAGGGG

>LR134090|1|1|735671-735770|CRISPRCasFinder
AAGATCCCCTAATTAATAAATTAAAAGGGG	ACTAAAGGAATACAGTTGATTGCTAATGCACCAACAGCAA
AAGAGCCCCTAATTAATAAATTAAAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ25526.1\|731800_732226_+\|accessory-regulator	unknown	unknown	gnl\|CDD\|130944
LR134090.1\|VDZ25549.1\|739427_739727_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ25511.1\|724847_725465_+\|phosphate-transport-regulator,-putative	unknown	unknown	gnl\|CDD\|224310
LR134090.1\|VDZ25516.1\|727072_727870_-\|Secretory-antigen-precursor-SsaA	unknown	unknown	gnl\|CDD\|226451
LR134090.1\|VDZ25530.1\|733131_733605_+\|cupin-superfamily-protein	unknown	unknown	gnl\|CDD\|226072
LR134090.1\|VDZ25518.1\|728230_728875_+\|transporter	unknown	unknown	gnl\|CDD\|223742
LR134090.1\|VDZ25558.1\|741011_741470_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
LR134090.1\|VDZ25555.1\|740443_741010_-\|Lysine-decarboxylase-family	unknown	unknown	gnl\|CDD\|224527
LR134090.1\|VDZ25561.1\|741472_742156_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|234750
LR134090.1\|VDZ25514.1\|725480_726488_+\|low-affinity-inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
LR134090.1\|VDZ25564.1\|742326_743202_-\|undecaprenyl-diphosphatase	unknown	unknown	gnl\|CDD\|234712
LR134090.1\|VDZ25552.1\|739806_740349_+\|Acetyltransferase-GNAT-family	unknown	unknown	gnl\|CDD\|379112
LR134090.1\|VDZ25532.1\|733957_734602_+\|Protein-of-uncharacterised-function-(DUF402)	unknown	unknown	gnl\|CDD\|225188
LR134090.1\|VDZ25528.1\|732415_733132_+\|putative-DUF28-containing-protein	unknown	unknown	gnl\|CDD\|237084
LR134090.1\|VDZ25543.1\|738407_738851_+\|aminoglycoside-6'-N-Acetyltransferase-IK	unknown	unknown	gnl\|CDD\|366181
LR134090.1\|VDZ25521.1\|729570_731721_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
LR134090.1\|VDZ25535.1\|734717_735584_+\|hydrogen-peroxide-inducible-genes-activator	unknown	unknown	gnl\|CDD\|223656
LR134090.1\|VDZ25546.1\|738918_739290_+\|lipoprotein	unknown	unknown	unknown
LR134090.1\|VDZ25540.1\|737004_737493_+\|putative-glycine-zipper-protein	unknown	unknown	gnl\|CDD\|225395
LR134090.1\|VDZ25541.1\|737591_738281_-\|membrane-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ25526.1\|731800_732226_+\|accessory-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	5.92419e-24
LR134090.1\|VDZ25511.1\|724847_725465_+\|phosphate-transport-regulator,-putative	gnl\|CDD\|224310	COG1392, COG1392, Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism].	3.27806e-54
LR134090.1\|VDZ25516.1\|727072_727870_-\|Secretory-antigen-precursor-SsaA	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.27934e-40
LR134090.1\|VDZ25530.1\|733131_733605_+\|cupin-superfamily-protein	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	7.22926e-75
LR134090.1\|VDZ25518.1\|728230_728875_+\|transporter	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	4.23058e-32
LR134090.1\|VDZ25558.1\|741011_741470_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	4.00232e-76
LR134090.1\|VDZ25555.1\|740443_741010_-\|Lysine-decarboxylase-family	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	2.12326e-61
LR134090.1\|VDZ25561.1\|741472_742156_-\|Uncharacterised-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000865945
LR134090.1\|VDZ25514.1\|725480_726488_+\|low-affinity-inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	2.03179e-103
LR134090.1\|VDZ25564.1\|742326_743202_-\|undecaprenyl-diphosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	1.23471e-100
LR134090.1\|VDZ25552.1\|739806_740349_+\|Acetyltransferase-GNAT-family	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.9646e-28
LR134090.1\|VDZ25532.1\|733957_734602_+\|Protein-of-uncharacterised-function-(DUF402)	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	1.2715e-91
LR134090.1\|VDZ25528.1\|732415_733132_+\|putative-DUF28-containing-protein	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
LR134090.1\|VDZ25543.1\|738407_738851_+\|aminoglycoside-6'-N-Acetyltransferase-IK	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.55516e-13
LR134090.1\|VDZ25521.1\|729570_731721_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.04881e-20
LR134090.1\|VDZ25535.1\|734717_735584_+\|hydrogen-peroxide-inducible-genes-activator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.04787e-39
LR134090.1\|VDZ25540.1\|737004_737493_+\|putative-glycine-zipper-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	2.67215e-44

>LR134090.1|VDZ25535.1|734717_735584_+|hydrogen-peroxide-inducible-genes-activator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>LR134090.1|VDZ25532.1|733957_734602_+|Protein-of-uncharacterised-function-(DUF402)
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNHQKPQNKTNFEKSKQIKPKQYNQTKNHQQQKKN
>LR134090.1|VDZ25530.1|733131_733605_+|cupin-superfamily-protein
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPKGTIFASSIEISNTYSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>LR134090.1|VDZ25528.1|732415_733132_+|putative-DUF28-containing-protein
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>LR134090.1|VDZ25526.1|731800_732226_+|accessory-regulator
MAGKFKIIMTEALSLYIWGCNILNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNDDDISKFNALFEDVEQFLNI
>LR134090.1|VDZ25521.1|729570_731721_+|AraC-family-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADVRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFAIIKTIIESDLKIAFNINDIDTTYYVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKEQDLSNSAPLIYKTLSALYHNFAGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSNNSLNINVTFNALYIIKIGKK
>LR134090.1|VDZ25518.1|728230_728875_+|transporter
MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLCTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>LR134090.1|VDZ25516.1|727072_727870_-|Secretory-antigen-precursor-SsaA
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>LR134090.1|VDZ25514.1|725480_726488_+|low-affinity-inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISAFLAAFLFYILNLFF
>LR134090.1|VDZ25511.1|724847_725465_+|phosphate-transport-regulator,-putative
MFSKKKDKFMVQLEEMVFNLDRAAIEFGKMDFNTHLDLKAYSDNIKTYESHGDELVHQVITDLNQTFITPIEREDILSLCDAIDDVLDAIEETAAMFEMYSIEYTDEYMAEFVDNIQKAVAEMKLAVGLLVDKKLSHMRIHSINIKEFETNCDGILRQSIKHIFNSETDPITLIKIKDIYESMEEIADKCQIVANNFETIIMKNS
>LR134090.1|VDZ25540.1|737004_737493_+|putative-glycine-zipper-protein
MTIILWLLILAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>LR134090.1|VDZ25541.1|737591_738281_-|membrane-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKSGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIEKNISKKHSHTFL
>LR134090.1|VDZ25543.1|738407_738851_+|aminoglycoside-6'-N-Acetyltransferase-IK
MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISSTIHKSNLPMISLNKDLGYQVSHVKMYKDID
>LR134090.1|VDZ25546.1|738918_739290_+|lipoprotein
MKKLIISIMSVMILLAGCGKSEEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKYKDKEASQDKQSKDQTKSSDKDNHKKPTSTDKDQKANDKHQS
>LR134090.1|VDZ25549.1|739427_739727_+|Uncharacterised-protein
MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>LR134090.1|VDZ25552.1|739806_740349_+|Acetyltransferase-GNAT-family
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKAALKLAEQHQIYDVYSFTAEANKASQRVMEKIGMPVYDHFELPNLSKYHLLKRQVRYYINLRK
>LR134090.1|VDZ25555.1|740443_741010_-|Lysine-decarboxylase-family
MKRIAVYCGASKGHDPSYIQKAYDLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>LR134090.1|VDZ25558.1|741011_741470_-|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVITQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQSGRHKGPPPFTKQDQKVFEQSLLRVIQRIKELD
>LR134090.1|VDZ25561.1|741472_742156_-|Uncharacterised-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKEEQKAREKNKIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA
>LR134090.1|VDZ25564.1|742326_743202_-|undecaprenyl-diphosphatase
MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFLGSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGENNQQRRSKPRRLNLLHVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSVKVKNPQTVDQINYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAASGLSLLKHYQDIQIADIPFYILGFLAAFTVGLIAIKTFLHLINKIKLIPFAIYRIVLVIFIAILYFGFGIGKGI

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Crispr_ID: LR134090_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_3

928085-928166

Orphan

Consensus_repeat	Method
CAATTTCTACAGGCAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_3

>merge|LR134090|3|928085-928166|CRISPRCasFinder
CAATTTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACACAGAGAAATTGGGGAGTCAATTTCTACAGACAATGCAAGTTGG

>LR134090|3|2|928085-928166|CRISPRCasFinder
CAATTTCTACAGGCAATGCAAGTTGG	CGGGGCCCCAACACAGAGAAATTGGGGAGT
CAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ26097.1\|935741_936317_+\|Signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
LR134090.1\|VDZ26076.1\|925386_926577_+\|Ornithine-aminotransferase	unknown	unknown	gnl\|CDD\|179736
LR134090.1\|VDZ26091.1\|934621_935197_+\|SNARE-associated-Golgi-family-protein	unknown	unknown	gnl\|CDD\|223475
LR134090.1\|VDZ26057.1\|918800_919229_-\|Na(+)-H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
LR134090.1\|VDZ26060.1\|919221_921627_-\|Na(+)-H(+)-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
LR134090.1\|VDZ26088.1\|932418_933750_+\|Glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
LR134090.1\|VDZ26106.1\|943772_944675_+\|Fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
LR134090.1\|VDZ26084.1\|929494_930874_-\|Argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
LR134090.1\|VDZ26100.1\|936476_939953_+\|helicase-exonuclease-AddAB,-AddB-subunit	unknown	unknown	gnl\|CDD\|213736
LR134090.1\|VDZ26069.1\|923213_923591_+\|general-stress-protein-13	unknown	unknown	gnl\|CDD\|224023
LR134090.1\|VDZ26081.1\|928323_929253_-\|putative-glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
LR134090.1\|VDZ26086.1\|930863_932069_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
LR134090.1\|VDZ26063.1\|921757_922141_-\|kinase-associated-B-family-protein	unknown	unknown	gnl\|CDD\|378054
LR134090.1\|VDZ26094.1\|935201_935726_+\|Signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
LR134090.1\|VDZ26072.1\|923951_925079_+\|Putative-NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
LR134090.1\|VDZ26066.1\|922204_922798_+\|Peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
LR134090.1\|VDZ26051.1\|916970_918467_-\|Na(+)-H(+)-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
LR134090.1\|VDZ26054.1\|918459_918801_-\|Na+/H+-antiporter-subunit	unknown	unknown	gnl\|CDD\|181497
LR134090.1\|VDZ26078.1\|926685_927930_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
LR134090.1\|VDZ26103.1\|939953_943607_+\|ATP-dependent-nuclease,-subunit-A	unknown	unknown	gnl\|CDD\|274299

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ26097.1\|935741_936317_+\|Signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
LR134090.1\|VDZ26076.1\|925386_926577_+\|Ornithine-aminotransferase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
LR134090.1\|VDZ26091.1\|934621_935197_+\|SNARE-associated-Golgi-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	3.53252e-40
LR134090.1\|VDZ26057.1\|918800_919229_-\|Na(+)-H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
LR134090.1\|VDZ26060.1\|919221_921627_-\|Na(+)-H(+)-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
LR134090.1\|VDZ26088.1\|932418_933750_+\|Glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
LR134090.1\|VDZ26106.1\|943772_944675_+\|Fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
LR134090.1\|VDZ26084.1\|929494_930874_-\|Argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
LR134090.1\|VDZ26100.1\|936476_939953_+\|helicase-exonuclease-AddAB,-AddB-subunit	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
LR134090.1\|VDZ26069.1\|923213_923591_+\|general-stress-protein-13	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
LR134090.1\|VDZ26081.1\|928323_929253_-\|putative-glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.0773e-151
LR134090.1\|VDZ26086.1\|930863_932069_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
LR134090.1\|VDZ26063.1\|921757_922141_-\|kinase-associated-B-family-protein	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
LR134090.1\|VDZ26094.1\|935201_935726_+\|Signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.90097e-49
LR134090.1\|VDZ26072.1\|923951_925079_+\|Putative-NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
LR134090.1\|VDZ26066.1\|922204_922798_+\|Peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
LR134090.1\|VDZ26051.1\|916970_918467_-\|Na(+)-H(+)-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
LR134090.1\|VDZ26054.1\|918459_918801_-\|Na+/H+-antiporter-subunit	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64
LR134090.1\|VDZ26078.1\|926685_927930_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
LR134090.1\|VDZ26103.1\|939953_943607_+\|ATP-dependent-nuclease,-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0

>LR134090.1|VDZ26078.1|926685_927930_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>LR134090.1|VDZ26076.1|925386_926577_+|Ornithine-aminotransferase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>LR134090.1|VDZ26072.1|923951_925079_+|Putative-NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNDAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIKQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>LR134090.1|VDZ26069.1|923213_923591_+|general-stress-protein-13
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>LR134090.1|VDZ26066.1|922204_922798_+|Peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>LR134090.1|VDZ26063.1|921757_922141_-|kinase-associated-B-family-protein
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>LR134090.1|VDZ26060.1|919221_921627_-|Na(+)-H(+)-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIHGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>LR134090.1|VDZ26057.1|918800_919229_-|Na(+)-H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>LR134090.1|VDZ26054.1|918459_918801_-|Na+/H+-antiporter-subunit
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>LR134090.1|VDZ26051.1|916970_918467_-|Na(+)-H(+)-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPLRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>LR134090.1|VDZ26081.1|928323_929253_-|putative-glycerophosphoryl-diester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGRVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>LR134090.1|VDZ26084.1|929494_930874_-|Argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>LR134090.1|VDZ26086.1|930863_932069_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAIECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFVKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>LR134090.1|VDZ26088.1|932418_933750_+|Glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>LR134090.1|VDZ26091.1|934621_935197_+|SNARE-associated-Golgi-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLALSKLVSTIILGYLGKEITTILTHPLRGIIMLVVLIVFWIVGKKLEQHFMGSKKE
>LR134090.1|VDZ26094.1|935201_935726_+|Signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLVDKKDIIGNISLTYYPFSKWTIQFKS
>LR134090.1|VDZ26097.1|935741_936317_+|Signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>LR134090.1|VDZ26100.1|936476_939953_+|helicase-exonuclease-AddAB,-AddB-subunit
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQNTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDLLNQGLDYLMSALTFDNETVKLGETLSKELYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNINIDDEFGGEQ
>LR134090.1|VDZ26103.1|939953_943607_+|ATP-dependent-nuclease,-subunit-A
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDDTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVNYDESAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSKLYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>LR134090.1|VDZ26106.1|943772_944675_+|Fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: LR134090_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_5

1060419-1060515

Orphan

Consensus_repeat	Method
GCATAAAAGCCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_5

>merge|LR134090|5|1060419-1060515|CRISPRCasFinder
GCATAAAAGCCCCTAACAACTAAAAGTTGTAAGGTAAAAGAGGGATACTTGCGCTGAGCGCATGCATAAAAGCCCCTAACAACTAAAGGTTGTAAGG

>LR134090|5|4|1060419-1060515|CRISPRCasFinder
GCATAAAAGCCCCTAACAACTAAAAGTTGTAAGG	TAAAAGAGGGATACTTGCGCTGAGCGCAT
GCATAAAAGCCCCTAACAACTAAAGGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ26410.1\|1055637_1056885_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
LR134090.1\|VDZ26430.1\|1066673_1066907_-\|glutaredoxin	unknown	unknown	gnl\|CDD\|239274
LR134090.1\|VDZ26402.1\|1051048_1052533_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
LR134090.1\|VDZ26420.1\|1060810_1062106_+\|membrane-spanning-protein	unknown	unknown	unknown
LR134090.1\|VDZ26422.1\|1062529_1063702_+\|LSU-m5C1962-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|224017
LR134090.1\|VDZ26436.1\|1069614_1070277_+\|Trk-system-potassium-uptake-protein-trkA	unknown	unknown	gnl\|CDD\|223643
LR134090.1\|VDZ26406.1\|1053556_1054123_+\|Phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
LR134090.1\|VDZ26424.1\|1063755_1064298_+\|Radical-activating-enzyme-protein	unknown	unknown	gnl\|CDD\|368297
LR134090.1\|VDZ26404.1\|1052525_1053554_+\|Phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
LR134090.1\|VDZ26400.1\|1048880_1051070_+\|Phosphoribosylformylglycinamidine-synthase,-synthetase-subunit	unknown	unknown	gnl\|CDD\|234921
LR134090.1\|VDZ26434.1\|1068462_1069482_+\|Cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
LR134090.1\|VDZ26408.1\|1054137_1055616_+\|IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
LR134090.1\|VDZ26418.1\|1060524_1060659_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ26412.1\|1057150_1057957_-\|hydroxymethylpyrimidine-transport-system-permease-protein	unknown	unknown	gnl\|CDD\|223692
LR134090.1\|VDZ26426.1\|1064451_1064718_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
LR134090.1\|VDZ26428.1\|1064720_1066439_+\|Phosphoenolpyruvate-protein-phosphotransferase-of-PTS-system	unknown	unknown	gnl\|CDD\|224006
LR134090.1\|VDZ26432.1\|1067104_1068466_+\|Cytochrome-d-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
LR134090.1\|VDZ26416.1\|1059365_1059941_-\|Substrate-specific-component-YkoE-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	unknown	unknown	gnl\|CDD\|227065
LR134090.1\|VDZ26414.1\|1057949_1059350_-\|Duplicated-ATPase-component-YkoD-of-energizing-module-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	unknown	unknown	gnl\|CDD\|213192
LR134090.1\|VDZ26398.1\|1048216_1048888_+\|Phosphoribosylformylglycinamidine-synthase	unknown	unknown	gnl\|CDD\|235140

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ26410.1\|1055637_1056885_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
LR134090.1\|VDZ26430.1\|1066673_1066907_-\|glutaredoxin	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.99976e-16
LR134090.1\|VDZ26402.1\|1051048_1052533_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
LR134090.1\|VDZ26422.1\|1062529_1063702_+\|LSU-m5C1962-methyltransferase-RlmI	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
LR134090.1\|VDZ26436.1\|1069614_1070277_+\|Trk-system-potassium-uptake-protein-trkA	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
LR134090.1\|VDZ26424.1\|1063755_1064298_+\|Radical-activating-enzyme-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00760449
LR134090.1\|VDZ26404.1\|1052525_1053554_+\|Phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
LR134090.1\|VDZ26400.1\|1048880_1051070_+\|Phosphoribosylformylglycinamidine-synthase,-synthetase-subunit	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
LR134090.1\|VDZ26434.1\|1068462_1069482_+\|Cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.67944e-76
LR134090.1\|VDZ26408.1\|1054137_1055616_+\|IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
LR134090.1\|VDZ26406.1\|1053556_1054123_+\|Phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	1.72008e-91
LR134090.1\|VDZ26412.1\|1057150_1057957_-\|hydroxymethylpyrimidine-transport-system-permease-protein	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.22352e-28
LR134090.1\|VDZ26426.1\|1064451_1064718_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
LR134090.1\|VDZ26428.1\|1064720_1066439_+\|Phosphoenolpyruvate-protein-phosphotransferase-of-PTS-system	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
LR134090.1\|VDZ26432.1\|1067104_1068466_+\|Cytochrome-d-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	7.19158e-165
LR134090.1\|VDZ26416.1\|1059365_1059941_-\|Substrate-specific-component-YkoE-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
LR134090.1\|VDZ26414.1\|1057949_1059350_-\|Duplicated-ATPase-component-YkoD-of-energizing-module-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	4.90758e-64
LR134090.1\|VDZ26398.1\|1048216_1048888_+\|Phosphoribosylformylglycinamidine-synthase	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	7.03361e-141

>LR134090.1|VDZ26416.1|1059365_1059941_-|Substrate-specific-component-YkoE-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>LR134090.1|VDZ26414.1|1057949_1059350_-|Duplicated-ATPase-component-YkoD-of-energizing-module-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine
MLKVSDLRLKYPNGQRKIFDHLNINIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLENVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>LR134090.1|VDZ26412.1|1057150_1057957_-|hydroxymethylpyrimidine-transport-system-permease-protein
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDVANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDVIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>LR134090.1|VDZ26410.1|1055637_1056885_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVHDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>LR134090.1|VDZ26408.1|1054137_1055616_+|IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>LR134090.1|VDZ26406.1|1053556_1054123_+|Phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>LR134090.1|VDZ26404.1|1052525_1053554_+|Phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVEEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDKNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGRIVKNESTAIEFLGV
>LR134090.1|VDZ26402.1|1051048_1052533_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>LR134090.1|VDZ26400.1|1048880_1051070_+|Phosphoribosylformylglycinamidine-synthase,-synthetase-subunit
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKNYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKVVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGVLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>LR134090.1|VDZ26398.1|1048216_1048888_+|Phosphoribosylformylglycinamidine-synthase
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELKIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>LR134090.1|VDZ26418.1|1060524_1060659_-|Uncharacterised-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>LR134090.1|VDZ26420.1|1060810_1062106_+|membrane-spanning-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>LR134090.1|VDZ26422.1|1062529_1063702_+|LSU-m5C1962-methyltransferase-RlmI
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>LR134090.1|VDZ26424.1|1063755_1064298_+|Radical-activating-enzyme-protein
MGFKNNLTSNLTNKIGNSVFKIENINEKGAMPTTIKELNERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERVMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>LR134090.1|VDZ26426.1|1064451_1064718_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>LR134090.1|VDZ26428.1|1064720_1066439_+|Phosphoenolpyruvate-protein-phosphotransferase-of-PTS-system
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMNGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>LR134090.1|VDZ26430.1|1066673_1066907_-|glutaredoxin
MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDFDEINKVLNIQD
>LR134090.1|VDZ26432.1|1067104_1068466_+|Cytochrome-d-ubiquinol-oxidase-subunit-I
MDTVEISRFLIAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>LR134090.1|VDZ26434.1|1068462_1069482_+|Cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>LR134090.1|VDZ26436.1|1069614_1070277_+|Trk-system-potassium-uptake-protein-trkA
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: LR134090_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_6

1949187-1949269

Orphan

Consensus_repeat	Method
CAACATAGTGAAATTGGATCCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_6

>merge|LR134090|6|1949187-1949269|CRISPRCasFinder
CAACATAGTGAAATTGGATCCTCAATTTCTACAGACGATGCAAGTTGGGGAAACGGCCCCAACATAGTGAAATCGGATCCTCA

>LR134090|6|5|1949187-1949269|CRISPRCasFinder
CAACATAGTGAAATTGGATCCTCA	ATTTCTACAGACGATGCAAGTTGGGGAAACGGCCC
CAACATAGTGAAATCGGATCCTCA

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ28032.1\|1950513_1950984_-\|tRNA-(cytosine34-2-O-)-methyltransferase	unknown	unknown	gnl\|CDD\|223297
LR134090.1\|VDZ28046.1\|1966038_1966494_-\|Thiol-peroxidase,-Bcp-type	unknown	unknown	gnl\|CDD\|224146
LR134090.1\|VDZ28034.1\|1950988_1952116_-\|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl\|CDD\|272993
LR134090.1\|VDZ28022.1\|1945587_1946409_+\|ribosomal-large-subunit-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|223638
LR134090.1\|VDZ28040.1\|1954696_1955758_-\|Regulatory-protein	unknown	unknown	gnl\|CDD\|226167
LR134090.1\|VDZ28012.1\|1941131_1941476_-\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237467
LR134090.1\|VDZ28008.1\|1935931_1938868_-\|membrane-associated-protein	unknown	unknown	gnl\|CDD\|227061
LR134090.1\|VDZ28026.1\|1948440_1948836_-\|membrane-protein	unknown	unknown	unknown
LR134090.1\|VDZ28030.1\|1949755_1950355_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|223440
LR134090.1\|VDZ28038.1\|1952981_1954439_-\|extracellular-glutamine-binding-protein	unknown	unknown	gnl\|CDD\|223836
LR134090.1\|VDZ28042.1\|1964539_1964986_-\|Peroxide-stress-regulator-PerR,-FUR-family	unknown	unknown	gnl\|CDD\|223806
LR134090.1\|VDZ28028.1\|1949578_1949731_-\|putative-staphylococcal-protein	unknown	unknown	unknown
LR134090.1\|VDZ28020.1\|1944312_1945425_-\|Two-component-sensor-protein	unknown	unknown	gnl\|CDD\|226951
LR134090.1\|VDZ28010.1\|1938857_1940054_-\|DNA-repair-exonuclease-family-protein-YhaO	unknown	unknown	gnl\|CDD\|223497
LR134090.1\|VDZ28018.1\|1943667_1944291_-\|Two-component-response-regulator-like-protein	unknown	unknown	gnl\|CDD\|225107
LR134090.1\|VDZ28044.1\|1965082_1966042_-\|D-3-phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
LR134090.1\|VDZ28036.1\|1952266_1952995_-\|Glutamine-transport-ATP-binding-protein-glnQ	unknown	unknown	gnl\|CDD\|224051
LR134090.1\|VDZ28014.1\|1941544_1942669_-\|membrane-protein	unknown	unknown	gnl\|CDD\|226834
LR134090.1\|VDZ28016.1\|1942847_1943312_-\|HTH-domain-protein,-binds-to-mecA-promoter-region	unknown	unknown	gnl\|CDD\|224393
LR134090.1\|VDZ28024.1\|1946859_1948245_-\|Fumarate-hydratase-class-II	unknown	unknown	gnl\|CDD\|234779

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ28032.1\|1950513_1950984_-\|tRNA-(cytosine34-2-O-)-methyltransferase	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
LR134090.1\|VDZ28046.1\|1966038_1966494_-\|Thiol-peroxidase,-Bcp-type	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.44283e-68
LR134090.1\|VDZ28034.1\|1950988_1952116_-\|iron-sulfur-cluster-binding-protein	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	7.04522e-180
LR134090.1\|VDZ28022.1\|1945587_1946409_+\|ribosomal-large-subunit-pseudouridine-synthase-D	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.26261e-77
LR134090.1\|VDZ28040.1\|1954696_1955758_-\|Regulatory-protein	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.23611e-122
LR134090.1\|VDZ28012.1\|1941131_1941476_-\|putative-transcriptional-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	1.19759e-37
LR134090.1\|VDZ28008.1\|1935931_1938868_-\|membrane-associated-protein	gnl\|CDD\|227061	COG4717, COG4717, Uncharacterized conserved protein [Function unknown].	0
LR134090.1\|VDZ28030.1\|1949755_1950355_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
LR134090.1\|VDZ28038.1\|1952981_1954439_-\|extracellular-glutamine-binding-protein	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.48919e-98
LR134090.1\|VDZ28042.1\|1964539_1964986_-\|Peroxide-stress-regulator-PerR,-FUR-family	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
LR134090.1\|VDZ28020.1\|1944312_1945425_-\|Two-component-sensor-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.05399e-57
LR134090.1\|VDZ28010.1\|1938857_1940054_-\|DNA-repair-exonuclease-family-protein-YhaO	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	7.33172e-64
LR134090.1\|VDZ28018.1\|1943667_1944291_-\|Two-component-response-regulator-like-protein	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.11819e-78
LR134090.1\|VDZ28044.1\|1965082_1966042_-\|D-3-phosphoglycerate-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.77676e-134
LR134090.1\|VDZ28036.1\|1952266_1952995_-\|Glutamine-transport-ATP-binding-protein-glnQ	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.22702e-152
LR134090.1\|VDZ28014.1\|1941544_1942669_-\|membrane-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	2.77221e-164
LR134090.1\|VDZ28024.1\|1946859_1948245_-\|Fumarate-hydratase-class-II	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
LR134090.1\|VDZ28016.1\|1942847_1943312_-\|HTH-domain-protein,-binds-to-mecA-promoter-region	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	5.18868e-15

>LR134090.1|VDZ28026.1|1948440_1948836_-|membrane-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>LR134090.1|VDZ28024.1|1946859_1948245_-|Fumarate-hydratase-class-II
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>LR134090.1|VDZ28022.1|1945587_1946409_+|ribosomal-large-subunit-pseudouridine-synthase-D
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMNKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>LR134090.1|VDZ28020.1|1944312_1945425_-|Two-component-sensor-protein
MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGVSNESIAKQAFKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK
>LR134090.1|VDZ28018.1|1943667_1944291_-|Two-component-response-regulator-like-protein
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI
>LR134090.1|VDZ28016.1|1942847_1943312_-|HTH-domain-protein,-binds-to-mecA-promoter-region
MDRQSFTDLIQTKFKMVRIEAGYTQDTMAQTIGLSKKTLVQIEKERVLPNWTTCISICALFRDSEVLNSTFGCDPLEIVQTISRNHCAYPNHAPTSDIYWNNIETRNGYILQSNKVSNIYRVLNPDNQPIFGTSKMREAETYFNRNAKEELVHI
>LR134090.1|VDZ28014.1|1941544_1942669_-|membrane-protein
MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKVTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLDQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQELIRLTSHPKARAIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEQLSIHLSAIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV
>LR134090.1|VDZ28012.1|1941131_1941476_-|putative-transcriptional-regulator
MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
>LR134090.1|VDZ28010.1|1938857_1940054_-|DNA-repair-exonuclease-family-protein-YhaO
MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDIALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGRHFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQVREEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDESPLVNEFSAELLVDQTVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMRGEQNDN
>LR134090.1|VDZ28008.1|1935931_1938868_-|membrane-associated-protein
MIIKSLEIYGYGQFVQRKIEFNKNFTEIFGENEAGKSTIQAFIHSILFGFPTKKSKEPRLEPRLGNQYGGKLVLILDDGLEIEVERIKGSAQGDVKVYLPNGAVRDDAWLQKKLNYISKKTYQGIFSFDVLGLQDIHRNLNEKQLQDYLLQAGALGSTEFTSMREVINRKKDELYKKSGKNPIINQQIEQLKQLESQIREEEAKLETYHRLVDDRDKSSRRLENLKHNLNQLSKMHEEKQKEVALHDHSQEWKSLEQQLNIEPITFPEKGVDRYEKARAHKQSLERDIGLRNERLAQLKEEATQLEPVKQSDIDAFISLNQQENEIKNKEFELTAIEKDIANKQRDKDELQANIGWSETHHDVDSSEAMKSYVSEQIKNKQEQAAYIKQLERSLEENKIEDNAVHSELDSVEEKIVPEETFEKKKEYSQQVIELNEKENLYSKLKERFEIEQQEKQKRQKLLRTTFILLTLVGIGLTAFSFISNNMLFGIIFAVLTLVFVIGIIMSKSKEVDYSEAITDEIEEIKEQLAILDENYDLDFDLDEQYRIRDHWQQALKNKDILEEKRQYIEGRLNDAKGRHDELQSTVENVKDELYLSSKISNDLIVDSISTMANIKALDQHISDLNQQRQQLVQELDTFYNHAEAVTKSQFVYFNKLSLFHDVQQWLKSAEDTNEKWRINAENTKLVTNELNHLNAQLEENNKEITALFDFINVGTEEDFYQHHEDYQTYTSNLSRFNDLTKYLENQNYSYELSSSLSEKTTAQLEEEDHLLATQVDEYNEQYLEMQAQVSDLSAQINHMETDTTLANLRHEYHSLKNQLNDIAKDWASLSYLQSLVDEHIKQIKDKRLPQVINEAVEILKHLTDGRYTMINYNEDSITVKHVNGQLYDPVELSQSTKELLYVALRISLIKVLRPYYPFPLIVDDAFVHFDKKRTEKMLNYLRSLSEHYQVLYFTCVKDNIVPSKEVITLNKIEEGGKR
>LR134090.1|VDZ28028.1|1949578_1949731_-|putative-staphylococcal-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>LR134090.1|VDZ28030.1|1949755_1950355_-|glucosamine-6-phosphate-deaminase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>LR134090.1|VDZ28032.1|1950513_1950984_-|tRNA-(cytosine34-2-O-)-methyltransferase
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>LR134090.1|VDZ28034.1|1950988_1952116_-|iron-sulfur-cluster-binding-protein
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDKEDAEVQNEMIKGLDTRRE
>LR134090.1|VDZ28036.1|1952266_1952995_-|Glutamine-transport-ATP-binding-protein-glnQ
MPVIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>LR134090.1|VDZ28038.1|1952981_1954439_-|extracellular-glutamine-binding-protein
MKCLIRFILILGLLISSAMVYINPTAHAEQDQAWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>LR134090.1|VDZ28040.1|1954696_1955758_-|Regulatory-protein
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTELNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>LR134090.1|VDZ28042.1|1964539_1964986_-|Peroxide-stress-regulator-PerR,-FUR-family
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>LR134090.1|VDZ28044.1|1965082_1966042_-|D-3-phosphoglycerate-dehydrogenase
MTYMRVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLADLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATKTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEPLLIEILKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>LR134090.1|VDZ28046.1|1966038_1966494_-|Thiol-peroxidase,-Bcp-type
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG

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Crispr_ID: LR134090_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_7

2244840-2244929

Orphan

Consensus_repeat	Method
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of LR134090_7

>merge|LR134090|7|2244840-2244929|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTACAACTTTAGTTGTTAGGGGCTCTTATGCA

>LR134090|7|6|2244840-2244929|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTT
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ28446.1\|2260756_2261191_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
LR134090.1\|VDZ28439.1\|2248294_2249152_-\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|223635
LR134090.1\|VDZ28429.1\|2236796_2237210_-\|thiol-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|225556
LR134090.1\|VDZ28442.1\|2252398_2254402_-\|recombinational-DNA-repair-ATPase,-RecF_1	unknown	unknown	gnl\|CDD\|226121
LR134090.1\|VDZ28431.1\|2239714_2239945_-\|membrane-protein	unknown	unknown	unknown
LR134090.1\|VDZ28443.1\|2254553_2256359_-\|glucosamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
LR134090.1\|VDZ28430.1\|2237667_2239041_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
LR134090.1\|VDZ28444.1\|2257039_2258578_+\|PTS-system,-mannitol-specific-IIBC-component	unknown	unknown	gnl\|CDD\|225123
LR134090.1\|VDZ28434.1\|2242166_2242487_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
LR134090.1\|VDZ28435.1\|2242488_2243469_+\|Cobalt-zinc-cadmium-resistance-protein	unknown	unknown	gnl\|CDD\|224151
LR134090.1\|VDZ28436.1\|2243734_2244826_+\|Lytic-regulatory-protein	unknown	unknown	unknown
LR134090.1\|VDZ28432.1\|2239975_2240914_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
LR134090.1\|VDZ28433.1\|2241349_2242015_-\|oxidoreductase-ylbE	unknown	unknown	gnl\|CDD\|187554
LR134090.1\|VDZ28427.1\|2235322_2236033_+\|Purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
LR134090.1\|VDZ28428.1\|2236153_2236597_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	unknown	unknown	gnl\|CDD\|223854
LR134090.1\|VDZ28440.1\|2249219_2250002_-\|ATP-binding-ATP-transporter-protein	unknown	unknown	gnl\|CDD\|224044
LR134090.1\|VDZ28438.1\|2247117_2247246_-\|SAP-domain-protein	unknown	unknown	unknown
LR134090.1\|VDZ28441.1\|2250480_2252406_-\|ATP-dependent-DNA-helicase	unknown	unknown	gnl\|CDD\|223288
LR134090.1\|VDZ28437.1\|2246125_2246833_-\|SAP-domain-protein	unknown	unknown	unknown
LR134090.1\|VDZ28445.1\|2258612_2260745_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ28446.1\|2260756_2261191_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
LR134090.1\|VDZ28435.1\|2242488_2243469_+\|Cobalt-zinc-cadmium-resistance-protein	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.73825e-109
LR134090.1\|VDZ28429.1\|2236796_2237210_-\|thiol-disulfide-oxidoreductase	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	1.9904e-45
LR134090.1\|VDZ28442.1\|2252398_2254402_-\|recombinational-DNA-repair-ATPase,-RecF_1	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	1.17368e-29
LR134090.1\|VDZ28443.1\|2254553_2256359_-\|glucosamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
LR134090.1\|VDZ28430.1\|2237667_2239041_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
LR134090.1\|VDZ28444.1\|2257039_2258578_+\|PTS-system,-mannitol-specific-IIBC-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
LR134090.1\|VDZ28434.1\|2242166_2242487_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
LR134090.1\|VDZ28439.1\|2248294_2249152_-\|Putative-cytosolic-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.04041e-59
LR134090.1\|VDZ28432.1\|2239975_2240914_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
LR134090.1\|VDZ28433.1\|2241349_2242015_-\|oxidoreductase-ylbE	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.60938e-47
LR134090.1\|VDZ28427.1\|2235322_2236033_+\|Purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
LR134090.1\|VDZ28428.1\|2236153_2236597_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
LR134090.1\|VDZ28440.1\|2249219_2250002_-\|ATP-binding-ATP-transporter-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	3.34818e-98
LR134090.1\|VDZ28441.1\|2250480_2252406_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.52057e-50
LR134090.1\|VDZ28445.1\|2258612_2260745_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.14637e-68

>LR134090.1|VDZ28436.1|2243734_2244826_+|Lytic-regulatory-protein
MFTYFKSALKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQNIAIYSQFGQKPPGDEYLKVIAVLLIAAIVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGIYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>LR134090.1|VDZ28435.1|2242488_2243469_+|Cobalt-zinc-cadmium-resistance-protein
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHQAHHHAHVH
>LR134090.1|VDZ28434.1|2242166_2242487_+|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>LR134090.1|VDZ28433.1|2241349_2242015_-|oxidoreductase-ylbE
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>LR134090.1|VDZ28432.1|2239975_2240914_-|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>LR134090.1|VDZ28431.1|2239714_2239945_-|membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>LR134090.1|VDZ28430.1|2237667_2239041_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>LR134090.1|VDZ28429.1|2236796_2237210_-|thiol-disulfide-oxidoreductase
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>LR134090.1|VDZ28428.1|2236153_2236597_-|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>LR134090.1|VDZ28427.1|2235322_2236033_+|Purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>LR134090.1|VDZ28437.1|2246125_2246833_-|SAP-domain-protein
MVENYIDENCDDKVAEIYKFEFQRKYDNCDFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNVYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASDMYERLIYNKNLSNNIIFELFKKDTQDYSDLEEQLIEKFINYVVSYVKKEGWSNTLLELSKMLENGYTIDKEDEYLSKYIITDIDYLKKLESKINVAIDSRSGEIHLILDDDSLDILIQNQKYGNEF
>LR134090.1|VDZ28438.1|2247117_2247246_-|SAP-domain-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDFEIINSIKN
>LR134090.1|VDZ28439.1|2248294_2249152_-|Putative-cytosolic-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMICSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>LR134090.1|VDZ28440.1|2249219_2250002_-|ATP-binding-ATP-transporter-protein
MLITLNHVGRLKQGKPILQDVSWQIDEGDKWVLYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKLGYSAENVRQQIGFVSHSLLEKFQEGETVIDVVMSGAFKSIGLYKNVDDDIISEAHQLLKLVEMSDKAQQFIGYLSTGEKQRVMIARALMGQPRILILDEPAAGLDFIARESLLNILDSLSDTYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSYFFRKKVAVQRWNNRFSMAMLE
>LR134090.1|VDZ28441.1|2250480_2252406_-|ATP-dependent-DNA-helicase
MNNRILEHEWKPSDDVTLEDSALHAIRASSHVAIAAGPGAGKTELLAHKAGYLIETGMCPYPKKILAISFKTDAARNLQERVELRYGKGVEKRFESKTFDAFAKGILDQFIHALPKEYQPQKNYEIILNEKSLNDIINAYITEPYSYYSNWQYEYHINSVLRTMKETKLPIVSFEDDLYSWINERLWMALLNGKGNLKSSLTFSMISILVEYLLKENPLLVKALQATYSHVFLDEFQDTTHIQYNLLKTIFLKSNTVITAVGDNKQRIMGWAGALQNAFGIFKTDFNATQYTLLNNFRSAPNLVYIQNIFSKTLNDASIEVLPAGEWNKNEGVCEIWNFKNHNIEAILLASYISKWMKVENLKPRDFCIIVKQHEHIYAAEIMKELSKINIKSRIEKDYQDLLSEELVLLIIRFLKLSYEEKSPELWLNVIDEIIDMKYSDADSESINYLIIEKELVKMLDEVRKLYSNINDTNFNTQFAEILQEIVVFLGEDIIKATYPKYNQANYFNEVMQKMIDKLQYQNCISMRGLVQEFCGEYSIPIMTIHKSKGLEYHTVFFIGVEDDAFWSFSTQKEADKNAFFVALSRAKQKIIFTISEKRNILKFGEEKNILQETKNISELIQTLMDAGVPLIEKSGLDNIL
>LR134090.1|VDZ28442.1|2252398_2254402_-|recombinational-DNA-repair-ATPase,-RecF_1
MLISELHISNFRSFGNESQMIEIADLTALIGANSSGKTSLIMALLRLFGQKNTDRTLIKTDFHIPESADISKINEIDLMIEAKVIFPELKLESPANIKTVPEFIKHLIIEETDADPYLRIRLKGKWIQGSTPEGNIEQELVYVKIPYGREEKEEDLTRVPIHHQKLIQMMYIPAMRDPAKQLKNASGTLLWRIFDGIDWPENLNDYIKSLTSPIETLFKEIPSIKDIQGILNNQWNKYHKDKRYSNSQFKFNGNSLQEFLKNAEILFNPTIDGNSVKVDSLGDGLKSLFYITLVSTLLEIENKQEKDDKPLLNILAIEEPENHISQHLLGRIVRNLKEISKKDNAQVILSSHNSSIIGKVDPEYIRHLQIQNSESIVNNITLPEKNDDAHTYIKEAVKAYPDLYFSKLVILGEGDSEEIVLPKLLSADNIYLDDFNISVVPLGGRYVNHMWKLLNDLSIPHVTLLDLDRERGGGDWGRIKYVLKQLDENNRCSEQLRTVLLIPSNTYHTYSMEEIEDFHNRKSNRLNSLNTWIEKLEKEDVFFSYPLDLDFTMLMSFQEEYQNTMERGPQIPKDSNSTEYDEKLKKSIQATLKNEKAIAKTYSEDEKKLMIWYNSLFLGRGKPSTHIAALKDIDENEIIENAPKELLRLIQRVKEKVGLVGGSNIDE
>LR134090.1|VDZ28443.1|2254553_2256359_-|glucosamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>LR134090.1|VDZ28444.1|2257039_2258578_+|PTS-system,-mannitol-specific-IIBC-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIVGFKVLAPIMKFIMYILSVAVESLVHAHLLPVVSILVEPAKILFLNNAINHGVFTPLGTDQAAKVGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKTPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>LR134090.1|VDZ28445.1|2258612_2260745_+|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGEDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIASPYLTVNPLLPDSDISYVAQFLNTKSTFSETHDKSSNMIDKDDVHVETKDIHGNTSFENEQTSYLTSVLEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>LR134090.1|VDZ28446.1|2260756_2261191_+|PTS-system-mannitol-specific-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA

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Crispr_ID: LR134090_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_8

2366144-2366362

Orphan

Consensus_repeat	Method
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG	CRT

3 spacers

The CRISPR arrays of LR134090_8

>merge|LR134090|8|2366144-2366362|CRT
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTGACTTTTGTCAGCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGTCCCCCAACTTGCACATTATTGTATGCTGACTTGCTGTCAGCTTCTATGTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG

>LR134090|8|1|2366144-2366362|CRT
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG	ACTTTTGTCAGCTTCTGT
GTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTT	CTTTTTGAAATTCTCTAT
GTTGGGGCCCCGTCCCCCAACTTGCACATTATTGTATGCTG	ACTTGCTGTCAGCTTCTAT
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ28543.1\|2364123_2365335_+\|Major-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|341042
LR134090.1\|VDZ28538.1\|2357582_2360750_-\|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein	unknown	unknown	gnl\|CDD\|223911
LR134090.1\|VDZ28544.1\|2365436_2365787_-\|Transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
LR134090.1\|VDZ28547.1\|2368192_2368426_-\|Molybdopterin-converting-factor,-subunit-1	unknown	unknown	gnl\|CDD\|340452
LR134090.1\|VDZ28552.1\|2371191_2371698_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
LR134090.1\|VDZ28550.1\|2369373_2370633_-\|Molybdopterin-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|238452
LR134090.1\|VDZ28540.1\|2362520_2362772_+\|membrane-protein	unknown	unknown	unknown
LR134090.1\|VDZ28539.1\|2360866_2362132_-\|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis	unknown	unknown	gnl\|CDD\|225224
LR134090.1\|VDZ28554.1\|2372901_2373507_-\|Molybdenum-transport-ATP-binding-protein-modC	unknown	unknown	gnl\|CDD\|226628
LR134090.1\|VDZ28545.1\|2366544_2367567_-\|Molybdenum-cofactor-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|274250
LR134090.1\|VDZ28551.1\|2370695_2371190_+\|Molybdenum-cofactor-biosynthesis-protein-C	unknown	unknown	gnl\|CDD\|236483
LR134090.1\|VDZ28541.1\|2362763_2363528_-\|glyoxalase-like-domain-protein	unknown	unknown	gnl\|CDD\|379203
LR134090.1\|VDZ28549.1\|2368891_2369377_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
LR134090.1\|VDZ28546.1\|2367586_2368186_-\|molybdopterin-guanine-dinucleotide-biosynthesis-mobA	unknown	unknown	gnl\|CDD\|234725
LR134090.1\|VDZ28535.1\|2355638_2356547_-\|AEC-family-malonate-efflux-carrier	unknown	unknown	gnl\|CDD\|223751
LR134090.1\|VDZ28553.1\|2371728_2372733_-\|Molybdopterin-biosynthesis-MoeB-protein	unknown	unknown	gnl\|CDD\|181084
LR134090.1\|VDZ28536.1\|2356679_2356844_+\|DNA-repair/chromosome-segregation-ATPase	unknown	unknown	unknown
LR134090.1\|VDZ28537.1\|2357078_2357396_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ28542.1\|2363690_2364131_+\|MarR-family-regulatory-protein	unknown	unknown	gnl\|CDD\|197670
LR134090.1\|VDZ28548.1\|2368431_2368878_-\|Molybdenum-cofactor-biosynthesis-protein-E	unknown	unknown	gnl\|CDD\|223391

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ28543.1\|2364123_2365335_+\|Major-facilitator-family-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17031e-72
LR134090.1\|VDZ28538.1\|2357582_2360750_-\|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
LR134090.1\|VDZ28544.1\|2365436_2365787_-\|Transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
LR134090.1\|VDZ28552.1\|2371191_2371698_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.00506e-64
LR134090.1\|VDZ28550.1\|2369373_2370633_-\|Molybdopterin-biosynthesis-protein-A	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	1.37843e-157
LR134090.1\|VDZ28539.1\|2360866_2362132_-\|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	8.95714e-143
LR134090.1\|VDZ28554.1\|2372901_2373507_-\|Molybdenum-transport-ATP-binding-protein-modC	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	2.92314e-114
LR134090.1\|VDZ28545.1\|2366544_2367567_-\|Molybdenum-cofactor-biosynthesis-protein-A	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
LR134090.1\|VDZ28551.1\|2370695_2371190_+\|Molybdenum-cofactor-biosynthesis-protein-C	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.70933e-97
LR134090.1\|VDZ28541.1\|2362763_2363528_-\|glyoxalase-like-domain-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	8.12814e-39
LR134090.1\|VDZ28549.1\|2368891_2369377_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	1.3043e-49
LR134090.1\|VDZ28546.1\|2367586_2368186_-\|molybdopterin-guanine-dinucleotide-biosynthesis-mobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	1.09736e-66
LR134090.1\|VDZ28535.1\|2355638_2356547_-\|AEC-family-malonate-efflux-carrier	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	3.9513e-43
LR134090.1\|VDZ28553.1\|2371728_2372733_-\|Molybdopterin-biosynthesis-MoeB-protein	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	5.96924e-132
LR134090.1\|VDZ28547.1\|2368192_2368426_-\|Molybdopterin-converting-factor,-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	5.99629e-25
LR134090.1\|VDZ28542.1\|2363690_2364131_+\|MarR-family-regulatory-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.824e-15
LR134090.1\|VDZ28548.1\|2368431_2368878_-\|Molybdenum-cofactor-biosynthesis-protein-E	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	1.13754e-57

>LR134090.1|VDZ28544.1|2365436_2365787_-|Transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>LR134090.1|VDZ28543.1|2364123_2365335_+|Major-facilitator-family-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>LR134090.1|VDZ28542.1|2363690_2364131_+|MarR-family-regulatory-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVFLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>LR134090.1|VDZ28541.1|2362763_2363528_-|glyoxalase-like-domain-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNQSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>LR134090.1|VDZ28540.1|2362520_2362772_+|membrane-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>LR134090.1|VDZ28539.1|2360866_2362132_-|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>LR134090.1|VDZ28538.1|2357582_2360750_-|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGKIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>LR134090.1|VDZ28537.1|2357078_2357396_+|Uncharacterised-protein
MQFYLILLAILYLIVSFISIFKMEVIFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>LR134090.1|VDZ28536.1|2356679_2356844_+|DNA-repair/chromosome-segregation-ATPase
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>LR134090.1|VDZ28535.1|2355638_2356547_-|AEC-family-malonate-efflux-carrier
MTEQFTMIILLIALGYFLKRINYIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>LR134090.1|VDZ28545.1|2366544_2367567_-|Molybdenum-cofactor-biosynthesis-protein-A
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>LR134090.1|VDZ28546.1|2367586_2368186_-|molybdopterin-guanine-dinucleotide-biosynthesis-mobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYRRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>LR134090.1|VDZ28547.1|2368192_2368426_-|Molybdopterin-converting-factor,-subunit-1
MKVLYFAEIKDILQKAQEDIMLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>LR134090.1|VDZ28548.1|2368431_2368878_-|Molybdenum-cofactor-biosynthesis-protein-E
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGIKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>LR134090.1|VDZ28549.1|2368891_2369377_-|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVGVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>LR134090.1|VDZ28550.1|2369373_2370633_-|Molybdopterin-biosynthesis-protein-A
MVVEKRNPIQVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLIEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>LR134090.1|VDZ28551.1|2370695_2371190_+|Molybdenum-cofactor-biosynthesis-protein-C
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>LR134090.1|VDZ28552.1|2371191_2371698_-|molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>LR134090.1|VDZ28553.1|2371728_2372733_-|Molybdopterin-biosynthesis-MoeB-protein
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQLIDTKITYGDIWEGSHYSFGFSKMQRSACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>LR134090.1|VDZ28554.1|2372901_2373507_-|Molybdenum-transport-ATP-binding-protein-modC
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKTDEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: LR134090_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_9

2580334-2580429

Orphan

Consensus_repeat	Method
CAACTGTATTCCTCTATACCTGTAATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_9

>merge|LR134090|9|2580334-2580429|CRISPRCasFinder
CAACTGTATTCCTCTATACCTGTAATTTTAATTACTAGAGGCTCTTATACAGTTGTTGCGAAGCAAGCAACTGTATTCCTCTATACCTGTAATTTT

>LR134090|9|7|2580334-2580429|CRISPRCasFinder
CAACTGTATTCCTCTATACCTGTAATTTT	AATTACTAGAGGCTCTTATACAGTTGTTGCGAAGCAAG
CAACTGTATTCCTCTATACCTGTAATTTT

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ28753.1\|2586070_2586766_-\|Short-chain-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|226674
LR134090.1\|VDZ28752.1\|2585400_2585820_-\|membrane-protein	unknown	unknown	gnl\|CDD\|284628
LR134090.1\|VDZ28748.1\|2581192_2581555_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ28744.1\|2575566_2577165_-\|Oligopeptide-transporter-putative-substrate-binding-domain-protein	unknown	unknown	gnl\|CDD\|274072
LR134090.1\|VDZ28755.1\|2587606_2587798_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ28750.1\|2582872_2584411_+\|aminobenzoyl-glutamate-transport-protein	unknown	unknown	gnl\|CDD\|367668
LR134090.1\|VDZ28740.1\|2572198_2572948_-\|nickel-transport-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
LR134090.1\|VDZ28749.1\|2581818_2582637_-\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|181491
LR134090.1\|VDZ28739.1\|2570993_2572187_-\|Antibiotic-resistance-protein	unknown	unknown	gnl\|CDD\|341042
LR134090.1\|VDZ28757.1\|2588447_2588774_-\|Putative-cytosolic-protein	unknown	unknown	unknown
LR134090.1\|VDZ28742.1\|2573752_2574622_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	unknown	unknown	gnl\|CDD\|224094
LR134090.1\|VDZ28741.1\|2572940_2573756_-\|Oligopeptide-transporter-putative-ATPase-domain-protein	unknown	unknown	gnl\|CDD\|223521
LR134090.1\|VDZ28738.1\|2570020_2570770_+\|membrane-protein	unknown	unknown	unknown
LR134090.1\|VDZ28745.1\|2577307_2578609_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|226839
LR134090.1\|VDZ28756.1\|2588151_2588445_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ28747.1\|2579430_2580252_-\|Putative-Similar-to-diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|223331
LR134090.1\|VDZ28751.1\|2584522_2584945_-\|transposase	unknown	unknown	gnl\|CDD\|225039
LR134090.1\|VDZ28743.1\|2574618_2575554_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	unknown	unknown	gnl\|CDD\|223674
LR134090.1\|VDZ28746.1\|2578601_2579420_-\|nicotianamine-synthase	unknown	unknown	gnl\|CDD\|176222
LR134090.1\|VDZ28754.1\|2587065_2587347_+\|IraB-protein	unknown	unknown	gnl\|CDD\|377790

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ28753.1\|2586070_2586766_-\|Short-chain-alcohol-dehydrogenase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	9.67028e-99
LR134090.1\|VDZ28754.1\|2587065_2587347_+\|IraB-protein	gnl\|CDD\|377790	pfam07205, DUF1413, Domain of unknown function (DUF1413). This family consists of several hypothetical bacterial proteins which seem to be specific to firmicute species. Members of this family are typically around 100 residues in length. The function of this family is unknown.	6.5904e-16
LR134090.1\|VDZ28744.1\|2575566_2577165_-\|Oligopeptide-transporter-putative-substrate-binding-domain-protein	gnl\|CDD\|274072	TIGR02294, Nickel-binding_periplasmic_protein, nickel ABC transporter, nickel/metallophore periplasmic binding protein. Members of this family are periplasmic nickel-binding proteins of nickel ABC transporters. Most appear to be lipoproteins. This protein was previously (circa 2003) thought to mediate binding to nickel through water molecules, but is now thought to involve a chelating organic molecule, perhaps butane-1,2,4-tricarboxylate, acting as a metallophore. [Transport and binding proteins, Cations and iron carrying compounds].	0
LR134090.1\|VDZ28750.1\|2582872_2584411_+\|aminobenzoyl-glutamate-transport-protein	gnl\|CDD\|367668	pfam03806, ABG_transport, AbgT putative transporter family.	0
LR134090.1\|VDZ28740.1\|2572198_2572948_-\|nickel-transport-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.955e-107
LR134090.1\|VDZ28749.1\|2581818_2582637_-\|short-chain-dehydrogenase	gnl\|CDD\|181491	PRK08589, PRK08589, SDR family oxidoreductase.	0
LR134090.1\|VDZ28739.1\|2570993_2572187_-\|Antibiotic-resistance-protein	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.31594e-79
LR134090.1\|VDZ28742.1\|2573752_2574622_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.12719e-84
LR134090.1\|VDZ28741.1\|2572940_2573756_-\|Oligopeptide-transporter-putative-ATPase-domain-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.55691e-118
LR134090.1\|VDZ28752.1\|2585400_2585820_-\|membrane-protein	gnl\|CDD\|284628	pfam07252, DUF1433, Protein of unknown function (DUF1433). This family contains a number of hypothetical bacterial proteins of unknown function approximately 100 residues in length.	3.33575e-38
LR134090.1\|VDZ28745.1\|2577307_2578609_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|226839	COG4408, COG4408, Uncharacterized protein conserved in bacteria [Function unknown].	0
LR134090.1\|VDZ28747.1\|2579430_2580252_-\|Putative-Similar-to-diaminopimelate-epimerase	gnl\|CDD\|223331	COG0253, DapF, Diaminopimelate epimerase [Amino acid transport and metabolism].	1.49398e-71
LR134090.1\|VDZ28751.1\|2584522_2584945_-\|transposase	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.64055e-29
LR134090.1\|VDZ28743.1\|2574618_2575554_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.46808e-99
LR134090.1\|VDZ28746.1\|2578601_2579420_-\|nicotianamine-synthase	gnl\|CDD\|176222	cd08261, Zn_ADH7, Alcohol dehydrogenases of the MDR family. This group contains members identified as related to zinc-dependent alcohol dehydrogenase and other members of the MDR family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group includes various activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0.000101006

>LR134090.1|VDZ28747.1|2579430_2580252_-|Putative-Similar-to-diaminopimelate-epimerase
MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVCCEQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCSDLVQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVNQVTIEIQHLVETYVREQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASIGVFNNYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE
>LR134090.1|VDZ28746.1|2578601_2579420_-|nicotianamine-synthase
MNNFNNEIKLILQQYLEKFEAHYERVLQDNQYIEALETLMDDYSEFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDNIEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV
>LR134090.1|VDZ28745.1|2577307_2578609_-|Uncharacterized-protein-conserved-in-bacteria
MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLYQAYKKEKQFEVKIQNEAHQHLEGKFEINRLYKDVKNVKGEYETVVMAYTADAYYDTLQQLSLETLQSVKHVILISPTFGSQMIVEQFMSKFSQDIEVISFSTYLGDTRIVDKEAPNHVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPPLFMNDFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQVFRVPSVNLLQFMVKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYSAILIDPFSQPDENGHYFDFSAVPFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIQTPMIDQFLARYEASCQAYKDMHQDQHLSSQFNTNLFEEDKALVTKFLEINRTLS
>LR134090.1|VDZ28744.1|2575566_2577165_-|Oligopeptide-transporter-putative-substrate-binding-domain-protein
MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIGDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWEVSEDGKTYTFHLRDDVKFHDGTPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQVDDEGIFIPISHGSMTVVAPKDLEKVSFTQSQYELPFNEMQYK
>LR134090.1|VDZ28743.1|2574618_2575554_-|Oligopeptide-transporter-putative-membrane-permease-domain-protein
MFKFILKRIALMFPLMIVVSFMTFLLTYITNENPAVTILHAQGTPNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITLMLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYVLIVAVLFIVFNTLADIINALLNPRLREGAR
>LR134090.1|VDZ28742.1|2573752_2574622_-|Oligopeptide-transporter-putative-membrane-permease-domain-protein
MIILKRLLQDKGAVIALGIIVLYVFLGLAAPLVTFYDPNHIDTANKFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPEMVFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRSVKKGVVQS
>LR134090.1|VDZ28741.1|2572940_2573756_-|Oligopeptide-transporter-putative-ATPase-domain-protein
MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGKSITCKSIVGLNPERLRVTGDITFDGKPMLSLSEAQLKKYRGKDIAMVMQQGSRAFDPSTTVGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLMIALALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIADRVVVMKNGQLIEHGTRESVLHHPEHVYTKYLLSTKKKINDHFKHVMRGDVHD
>LR134090.1|VDZ28740.1|2572198_2572948_-|nickel-transport-ATP-binding-protein
MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESGSGKSTLSRMILGIEKPDKGCVTLNDQPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREILFEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKIEEQIPTSALHKSDNAYTRELIEKQLSF
>LR134090.1|VDZ28739.1|2570993_2572187_-|Antibiotic-resistance-protein
MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVIGIVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARVMQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNISLFAIVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAITVFAQFFKNKELLNSGIIMIVASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHPKYMVSVLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVGRNMLLGLFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPRPANSL
>LR134090.1|VDZ28738.1|2570020_2570770_+|membrane-protein
MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVFLTFGLVAVFTQQAPWGFSFPISMNISYLLAVIISLAIFRRMHEDAFVPMIRSQIVASAKYKWHILISFTLSIVLFLLLNHFYIFALNVDSFTVFDIYPLIREYGSISLIAIFSLTIILNTLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILASSATYLYLKSNRNFMVSYFYQLAVILVLHIFM
>LR134090.1|VDZ28748.1|2581192_2581555_-|Uncharacterised-protein
MLKEKESFRLLYQAIREIADKIGDNQLETNSVSLLLLDFDFEHEVFDELHLAILKYLNTVSIENISHSELLNLIGNTIPEDREINTFVKNKIIIGFANNYFPELQVLANEIKSDMASSLK
>LR134090.1|VDZ28749.1|2581818_2582637_-|short-chain-dehydrogenase
MKRLENKVAVVTGASTGIGQASAIALAQEGAYVLAVDIAEVVSETVDKIKSNGDKAKAYIVDIASEQQIDNFASEIREQFGHVDVLFNNAGVDNAAGRIHEYPTDVYDKIMNVDMRGTFLMTKMMLPLMMTKGGSIVNTASFSGQAADLYRSGYNAVKGAVINFTKSIAIEYGRDGIRANAIAPGTIETPLVDKLTGTCEDKEGKAFRENQKWMTPLGRLGKPEEVGKLVVFLASDESSFITGETIRIDGGVMAYTWPGEMLSDDSWKRTLE
>LR134090.1|VDZ28750.1|2582872_2584411_+|aminobenzoyl-glutamate-transport-protein
MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTWVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIAASVVVLLPTILLVTTKLIIPRLGQYDDRLMHDDHEETSSHITDKEAHALKWANISFIVTIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK
>LR134090.1|VDZ28751.1|2584522_2584945_-|transposase
MPYNYKKQNGELMSVMSQGEKFIHQSPVNDELSALIKLLISKINGCHYCVDIHKKELKELGVTQMKIDEVLSFRHLDLFTDQEKVTLEFAEMLNSIKDFKKFEIIDRLKSFYDEEQIIDLVFVVNQINGWNRLNIISDKL
>LR134090.1|VDZ28752.1|2585400_2585820_-|membrane-protein
MTKKHVFIIIGVILCICIVATVIYLKVKYDEKEKQKALYYKEQQERITLYLKHNTKEPNTIKTVHFTSLKTGPMGDAVIEGYINENKKADFVAYGSPEHNYQFGGDMIESEKLSELLKPANQLKSPDEIKEELDKKEGH
>LR134090.1|VDZ28753.1|2586070_2586766_-|Short-chain-alcohol-dehydrogenase
MTVLTDKVAVVTGAGSGIGEAIATLLHEEGVKVILAGRNKDKLQNVANQLAQDSVKVVPTDVTKKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSISPGMVDTAITAAYNPTDRKKLEPQDIAEAVLYALTQPKHVNVNEITVRPV
>LR134090.1|VDZ28754.1|2587065_2587347_+|IraB-protein
MTYHERVLALRAERKRTAFDFRFEDLFSKEEWLSMSLAERQKAEKAFRHEVKKLDDVRMPFSSAHDAQVKLYNVVYSYNGIKRNFKQVENEGF
>LR134090.1|VDZ28755.1|2587606_2587798_-|Uncharacterised-protein
MRKEIEALIFSDVSSYDIYVNTGVNQGLIGDIKDGYLTIDSMPYIDAERLYHFAMERKSLVTN
>LR134090.1|VDZ28756.1|2588151_2588445_-|Uncharacterised-protein
MWYDSVVERIPSVPSINAVLQMRQITAVIAPEHNRIHHDHKNKLKNDEELLINQMSSHFKKFKGEFDNVAQGDWVKKAKNELDDISKKLKNIQRTEV
>LR134090.1|VDZ28757.1|2588447_2588774_-|Putative-cytosolic-protein
MFTEYKKISDLETAYDEERRKLNDKLEQLQEIKHQIKLDCEYSYDCFLYLKNKMDYSQESNVKMTHIINEFNDEMTQRIKNEEMKIERSKDELKSEYLKEIEKMGGRE

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Crispr_ID: LR134090_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_10

2807623-2807701

Orphan

Consensus_repeat	Method
TTCTCTATGTTGGGGCCCCGCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_10

>merge|LR134090|10|2807623-2807701|CRISPRCasFinder
TTCTCTATGTTGGGGCCCCGCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTTTGTTGGGGCCCCGCCAA

>LR134090|10|8|2807623-2807701|CRISPRCasFinder
TTCTCTATGTTGGGGCCCCGCCAA	CTCGCATTGCCTGTAGAATTTCTTTTCGAAA
TTCTCTTTGTTGGGGCCCCGCCAA

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ28946.1\|2807798_2809844_-\|Lipase	unknown	unknown	gnl\|CDD\|224001
LR134090.1\|VDZ28944.1\|2805496_2806369_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|188448
LR134090.1\|VDZ28955.1\|2816836_2817451_-\|ATP-phosphoribosyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|172153
LR134090.1\|VDZ28948.1\|2811361_2811994_-\|Phosphoribosyl-AMP-cyclohydrolase-/-Phosphoribosyl-ATP-pyrophosphatase	unknown	unknown	gnl\|CDD\|235067
LR134090.1\|VDZ28953.1\|2814564_2815578_-\|Histidinol-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|223157
LR134090.1\|VDZ28950.1\|2812745_2813450_-\|Phosphoribosylformimino-5-aminoimidazole-carboxamide-ribotide-isomerase	unknown	unknown	gnl\|CDD\|172156
LR134090.1\|VDZ28942.1\|2803992_2805231_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-N-glycosyltransferase-IcaA	unknown	unknown	gnl\|CDD\|274866
LR134090.1\|VDZ28938.1\|2800285_2801053_-\|Manganese-dependent-protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|226870
LR134090.1\|VDZ28943.1\|2805194_2805500_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-protein-IcaD	unknown	unknown	gnl\|CDD\|188447
LR134090.1\|VDZ28940.1\|2801758_2802421_-\|chain-length-regulator-(capsular-polysaccharide-biosynthesis)	unknown	unknown	gnl\|CDD\|226453
LR134090.1\|VDZ28937.1\|2799550_2800051_-\|acetyltransferase-(GNAT)-family-protein	unknown	unknown	gnl\|CDD\|379326
LR134090.1\|VDZ28954.1\|2815593_2816844_-\|Histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|172308
LR134090.1\|VDZ28952.1\|2814017_2814596_-\|imidazoleglycerol-phosphate-dehydratase	unknown	unknown	gnl\|CDD\|153419
LR134090.1\|VDZ28936.1\|2799071_2799548_-\|Peptide-methionine-sulfoxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|235497
LR134090.1\|VDZ28949.1\|2811990_2812749_-\|Imidazole-glycerol-phosphate-synthase,-cyclase-subunit	unknown	unknown	gnl\|CDD\|234996
LR134090.1\|VDZ28951.1\|2813442_2814021_-\|Imidazole-glycerol-phosphate-synthase-amidotransferase-subunit	unknown	unknown	gnl\|CDD\|171871
LR134090.1\|VDZ28947.1\|2810561_2810825_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ28945.1\|2806355_2807408_+\|intercellular-adhesion-protein-icaC	unknown	unknown	gnl\|CDD\|226446
LR134090.1\|VDZ28939.1\|2801049_2801742_-\|Tyrosine-protein-kinase-EpsD	unknown	unknown	gnl\|CDD\|349772
LR134090.1\|VDZ28941.1\|2803268_2803829_-\|Biofilm-operon-icaABCD-HTH-type-negative-transcriptional-regulator-IcaR	unknown	unknown	gnl\|CDD\|376089

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ28946.1\|2807798_2809844_-\|Lipase	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	4.33785e-81
LR134090.1\|VDZ28944.1\|2805496_2806369_+\|polysaccharide-deacetylase	gnl\|CDD\|188448	TIGR03933, Poly-beta-16-N-acetyl-D-glucosamine_N-deacetylase, intercellular adhesin biosynthesis polysaccharide N-deacetylase. A common motif in bacterial biosynthesis of polysaccharide for export is modification that follows polymerization. This model describes a subfamily of polysaccharide N-deacetylases that acts on poly-beta-1,6-N-acetyl-D-glyscosamine as produced by Staphylococcus epidermidis and S. aureus. The end product in these species is designated polysaccharide intercellular adhesin (PIA), and this gene designated icaB (intercellular adhesion protein B). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Cellular processes, Pathogenesis].	5.71542e-151
LR134090.1\|VDZ28955.1\|2816836_2817451_-\|ATP-phosphoribosyltransferase-catalytic-subunit	gnl\|CDD\|172153	PRK13584, hisG, ATP phosphoribosyltransferase.	1.23748e-132
LR134090.1\|VDZ28948.1\|2811361_2811994_-\|Phosphoribosyl-AMP-cyclohydrolase-/-Phosphoribosyl-ATP-pyrophosphatase	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	3.01463e-110
LR134090.1\|VDZ28953.1\|2814564_2815578_-\|Histidinol-phosphate-aminotransferase	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	4.19528e-82
LR134090.1\|VDZ28950.1\|2812745_2813450_-\|Phosphoribosylformimino-5-aminoimidazole-carboxamide-ribotide-isomerase	gnl\|CDD\|172156	PRK13587, PRK13587, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Provisional.	2.03626e-167
LR134090.1\|VDZ28942.1\|2803992_2805231_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-N-glycosyltransferase-IcaA	gnl\|CDD\|274866	TIGR03937, Poly-beta-16-N-acetyl-D-glucosamine_synthase, poly-beta-1,6 N-acetyl-D-glucosamine synthase. Members of this protein family are biofilm-forming enzymes that polymerize N-acetyl-D-glucosamine residues in beta(1,6) linkage. One named members is IcaA (intercellular adhesin protein A), an enzyme that acts (with aid of subunit IcaD) in Polysaccharide Intercellular Adhesin (PIA) biosynthesis in Staphylococcus epidermis). The homologous member in E. coli is designated PgaC. Members are often encoded next to a polysaccharide deacetylase and involved in biofilm formation. Note that chitin, although also made from N-acetylglucosamine, is formed with beta-1,4 linkages.	0
LR134090.1\|VDZ28938.1\|2800285_2801053_-\|Manganese-dependent-protein-tyrosine-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.88344e-144
LR134090.1\|VDZ28943.1\|2805194_2805500_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-protein-IcaD	gnl\|CDD\|188447	TIGR03932, IcaD_partial, intracellular adhesion protein D. Members of this protein family are IcaD (intracellular adhesion protein D), which with catalytic subunit IcaA forms an N-acetylglucosaminyltransferase. In the absence of IcaC, this enzyme forms N-acetylglucosamine oligomers up to 20 in length. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.14464e-30
LR134090.1\|VDZ28940.1\|2801758_2802421_-\|chain-length-regulator-(capsular-polysaccharide-biosynthesis)	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.17617e-89
LR134090.1\|VDZ28937.1\|2799550_2800051_-\|acetyltransferase-(GNAT)-family-protein	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.58707e-14
LR134090.1\|VDZ28954.1\|2815593_2816844_-\|Histidinol-dehydrogenase	gnl\|CDD\|172308	PRK13770, PRK13770, histidinol dehydrogenase; Provisional.	0
LR134090.1\|VDZ28952.1\|2814017_2814596_-\|imidazoleglycerol-phosphate-dehydratase	gnl\|CDD\|153419	cd07914, IGPD, Imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase (IGPD; EC 4.2.1.19) catalyzes the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, the sixth step of histidine biosynthesis in plants and microorganisms where the histidine is synthesized de novo. There is an internal repeat in the protein domain that is related by pseudo-dyad symmetry, perhaps as a result of an ancient gene duplication. The apo-form of IGPD exists as a catalytically inactive trimer which, in the presence of specific divalent metal cations such as manganese (Mn2+), cobalt (Co2+), cadmium (Cd2+), nickel (Ni2+), iron (Fe2+) and zinc (Zn2+), assembles to form a biologically active high molecular weight metalloenzyme; a 24-mer with 4-3-2 symmetry. Each 24-mer has 24 active sites, and contains around 1.5 metal ions per monomer, each monomer contributing residues to three separate active sites. IGPD enzymes are monofunctional in fungi, plants, archaea and some eubacteria while they are encoded as bifunctional enzymes in other eubacteria, such that the enzyme is fused to histidinol-phosphate phosphatase, the penultimate enzyme of the histidine biosynthesis pathway. The histidine biosynthesis pathway is a potential target for development of herbicides, and IGPD is a target for the triazole phosphonate herbicides.	7.13364e-103
LR134090.1\|VDZ28936.1\|2799071_2799548_-\|Peptide-methionine-sulfoxide-reductase-MsrA	gnl\|CDD\|235497	PRK05528, PRK05528, peptide-methionine (S)-S-oxide reductase.	1.09071e-103
LR134090.1\|VDZ28949.1\|2811990_2812749_-\|Imidazole-glycerol-phosphate-synthase,-cyclase-subunit	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	1.94565e-155
LR134090.1\|VDZ28951.1\|2813442_2814021_-\|Imidazole-glycerol-phosphate-synthase-amidotransferase-subunit	gnl\|CDD\|171871	PRK13142, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	2.74199e-130
LR134090.1\|VDZ28945.1\|2806355_2807408_+\|intercellular-adhesion-protein-icaC	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	1.16088e-114
LR134090.1\|VDZ28939.1\|2801049_2801742_-\|Tyrosine-protein-kinase-EpsD	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.83977e-84
LR134090.1\|VDZ28941.1\|2803268_2803829_-\|Biofilm-operon-icaABCD-HTH-type-negative-transcriptional-regulator-IcaR	gnl\|CDD\|376089	pfam18665, TetR_C_37, Tetracyclin repressor-like, C-terminal domain. IcaR belongs to the tetracycline repressor (TetR) family of proteins, which are involved in a wide variety of gene regulations. It binds to a 42 bp region immediately upstream of the icaA gene. This entry represents the C-terminal domain which is involved in dimerization.	2.88245e-28

>LR134090.1|VDZ28945.1|2806355_2807408_+|intercellular-adhesion-protein-icaC
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
>LR134090.1|VDZ28944.1|2805496_2806369_+|polysaccharide-deacetylase
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATVIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
>LR134090.1|VDZ28943.1|2805194_2805500_+|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-protein-IcaD
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
>LR134090.1|VDZ28942.1|2803992_2805231_+|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-N-glycosyltransferase-IcaA
MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
>LR134090.1|VDZ28941.1|2803268_2803829_-|Biofilm-operon-icaABCD-HTH-type-negative-transcriptional-regulator-IcaR
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
>LR134090.1|VDZ28940.1|2801758_2802421_-|chain-length-regulator-(capsular-polysaccharide-biosynthesis)
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
>LR134090.1|VDZ28939.1|2801049_2801742_-|Tyrosine-protein-kinase-EpsD
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
>LR134090.1|VDZ28938.1|2800285_2801053_-|Manganese-dependent-protein-tyrosine-phosphatase
MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILQGLDNGSIQGINRSKYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYSNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF
>LR134090.1|VDZ28937.1|2799550_2800051_-|acetyltransferase-(GNAT)-family-protein
MVLRKVIMQDLDQIIALENIGFSPEEAATPEALKLRIEQIQETFIVAEKNDEVIGYINGPVIKERYISDDLFKNVPTNNSEGGYISVLGLVVAPNYQGQGIAGRLLNYFENLAKNQHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNIKKDDEV
>LR134090.1|VDZ28936.1|2799071_2799548_-|Peptide-methionine-sulfoxide-reductase-MsrA
MAVVYVAGGCLWGVEAFFTTIPGIIHTEVGRANGRSSKLDSPYDGYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNRQGNDIGEKYRTGLYSCVDDYLIEARQFIERRKDRDKIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISIDLLNKYK
>LR134090.1|VDZ28946.1|2807798_2809844_-|Lipase
MMKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKKSSLNNKNIQRDTTKNSNANPSDVNQGLEQAINDGKQSKVASQQQSKEADNSQDSNANNNLPSQSRTKEALPLNKSNQTSQPEIVNKTEIEKVQPQQNNQANDKITNYNFNNEKEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKGDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNNDNMISSITTLGTPHNGTHASDLAGNEALVKQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTNATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVHTREELQDFWHHLADDLVKTEKVTDTKQA
>LR134090.1|VDZ28947.1|2810561_2810825_-|Uncharacterised-protein
MKKLFNEYFFTTSQATALIIFSLPMTDLFTKNFLLYMLLFIVIIGSTFFIERELSKKYSLQEKAKKLCLSLLPINIIVVFIFFVFIL
>LR134090.1|VDZ28948.1|2811361_2811994_-|Phosphoribosyl-AMP-cyclohydrolase-/-Phosphoribosyl-ATP-pyrophosphatase
MTNYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGLVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
>LR134090.1|VDZ28949.1|2811990_2812749_-|Imidazole-glycerol-phosphate-synthase,-cyclase-subunit
MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
>LR134090.1|VDZ28950.1|2812745_2813450_-|Phosphoribosylformimino-5-aminoimidazole-carboxamide-ribotide-isomerase
MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDADWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVKQLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
>LR134090.1|VDZ28951.1|2813442_2814021_-|Imidazole-glycerol-phosphate-synthase-amidotransferase-subunit
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNKQNIIDQAETIILPGVGHFKDAMSEIKRLNLDAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGTDIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND
>LR134090.1|VDZ28952.1|2814017_2814596_-|imidazoleglycerol-phosphate-dehydratase
MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNATLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
>LR134090.1|VDZ28953.1|2814564_2815578_-|Histidinol-phosphate-aminotransferase
MIYIDKNESPITPLDEKTMTSIISATPYNLYPDAAYEQFKDAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDIAFLTAIADKMKAINGYFVIDEAYLDYGMAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIQRIQKIEHPYPLNVFTLNIATYIFRHRQETSRFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEQVMKGYVRYSIATASQLKQLEEIVKEWSTKYDLSKTTKHS
>LR134090.1|VDZ28954.1|2815593_2816844_-|Histidinol-dehydrogenase
MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYNLTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEKSVECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSKEVLAACYITQVNQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGIDQIAGPTEIALIIDDTADLDAIVYDVFAQAEHDELARTYVISEDAQVLKDLESRIAKALPNVDRYDIVSKSIANQHYLIHASNFDEACYVMNTIAPEHASIQTVNPQPYIEKVKYVGALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFDQIADSAQHIAHVEALYNHQQSILIRQS
>LR134090.1|VDZ28955.1|2816836_2817451_-|ATP-phosphoribosyltransferase-catalytic-subunit
MLRIAIAKGRLMDSLINYLDAIEFTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGIADIGIVGSDILDERHYNVNNLLDMPFGACHFAVAAKPETTNYRKIATSYVHTAEAYFKSKGIDVELIKLSGSVELACVVDMVDGIVDIVQTGTTLEANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA

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Crispr_ID: LR134090_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134090_11

2836943-2837028

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134090_11

>merge|LR134090|11|2836943-2837028|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>LR134090|11|9|2836943-2837028|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
LR134090.1\|VDZ28977.1\|2838987_2840865_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	unknown	unknown	gnl\|CDD\|235362
LR134090.1\|VDZ28966.1\|2828273_2829290_+\|nickel-transport-protein	unknown	unknown	gnl\|CDD\|225911
LR134090.1\|VDZ28980.1\|2842927_2843065_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
LR134090.1\|VDZ28971.1\|2834162_2834354_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134090.1\|VDZ28967.1\|2829532_2830345_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225073
LR134090.1\|VDZ28968.1\|2830640_2831153_-\|membrane-spanning-protein	unknown	unknown	gnl\|CDD\|225786
LR134090.1\|VDZ28974.1\|2836365_2836719_-\|Permease	unknown	unknown	gnl\|CDD\|288237
LR134090.1\|VDZ28979.1\|2842453_2842801_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
LR134090.1\|VDZ28973.1\|2835902_2836298_-\|membrane-protein	unknown	unknown	gnl\|CDD\|288237
LR134090.1\|VDZ28965.1\|2827533_2828109_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|181104
LR134090.1\|VDZ28970.1\|2832190_2834071_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
LR134090.1\|VDZ28978.1\|2840931_2842311_-\|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase	unknown	unknown	gnl\|CDD\|235392
LR134090.1\|VDZ28976.1\|2838268_2838988_-\|Ribosomal-RNA-small-subunit-methyltransferase-G	unknown	unknown	gnl\|CDD\|234637
LR134090.1\|VDZ28969.1\|2831442_2832201_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
LR134090.1\|VDZ28975.1\|2837386_2838226_-\|Chromosome-(plasmid)-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|275105
LR134090.1\|VDZ28972.1\|2835073_2835643_-\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|238045

Protein	Function_ID	Function_description	E-value
LR134090.1\|VDZ28977.1\|2838987_2840865_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
LR134090.1\|VDZ28966.1\|2828273_2829290_+\|nickel-transport-protein	gnl\|CDD\|225911	COG3376, HoxN, High-affinity nickel permease [Inorganic ion transport and metabolism].	6.0873e-170
LR134090.1\|VDZ28980.1\|2842927_2843065_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
LR134090.1\|VDZ28967.1\|2829532_2830345_+\|N-acetyltransferase	gnl\|CDD\|225073	COG2162, NhoA, Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism].	2.45311e-103
LR134090.1\|VDZ28968.1\|2830640_2831153_-\|membrane-spanning-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	5.06647e-22
LR134090.1\|VDZ28974.1\|2836365_2836719_-\|Permease	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	5.87211e-38
LR134090.1\|VDZ28979.1\|2842453_2842801_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	6.56083e-51
LR134090.1\|VDZ28973.1\|2835902_2836298_-\|membrane-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	4.93393e-38
LR134090.1\|VDZ28965.1\|2827533_2828109_+\|DNA-binding-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	4.72293e-10
LR134090.1\|VDZ28970.1\|2832190_2834071_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.34753e-06
LR134090.1\|VDZ28978.1\|2840931_2842311_-\|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
LR134090.1\|VDZ28976.1\|2838268_2838988_-\|Ribosomal-RNA-small-subunit-methyltransferase-G	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	6.82524e-96
LR134090.1\|VDZ28969.1\|2831442_2832201_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.13228e-111
LR134090.1\|VDZ28975.1\|2837386_2838226_-\|Chromosome-(plasmid)-partitioning-protein-ParB	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.327e-113
LR134090.1\|VDZ28972.1\|2835073_2835643_-\|helix-turn-helix-family-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.19983e-16

>LR134090.1|VDZ28974.1|2836365_2836719_-|Permease
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLASLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>LR134090.1|VDZ28973.1|2835902_2836298_-|membrane-protein
MKLTLMKFFVGGFAVLLSYIVSVALPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>LR134090.1|VDZ28972.1|2835073_2835643_-|helix-turn-helix-family-protein
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWAYVMLIFMTLAAILTGPLIVYWNWAWGITVMVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISVYLANKFL
>LR134090.1|VDZ28971.1|2834162_2834354_+|Uncharacterised-protein
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSTVTTPIIGIPVGLLGGAYYLKRREEKGK
>LR134090.1|VDZ28970.1|2832190_2834071_+|ABC-transporter-permease
MTFNHIVFKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTIFMLVIAYILILFQSSLFLKRRSILSMMKDSIKTDVTTAKVTTAEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFTKNYYETITVNNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNIINIHLNKDLVVKGTKNETFRVTQEDKGKVYPLNLSFNSPVVEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKVITYDEMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>LR134090.1|VDZ28969.1|2831442_2832201_+|ABC-transporter-ATP-binding-protein
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>LR134090.1|VDZ28968.1|2830640_2831153_-|membrane-spanning-protein
MEKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLFVLINGVIQIVYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFWFIFSSIAGLFTFSGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFLFVGVIYVVDALA
>LR134090.1|VDZ28967.1|2829532_2830345_+|N-acetyltransferase
MNIAKLENYLQIDSSRYNRPSIEALNYYATRFMLTVPFENIDVQNSKPISINIDALFNKIVRDKRGGFCYELNTFFKTYLQQKGFNPELMSATIHTPGGGRSLNGSHASLVVSINDVFYVTDVGFGDLPLHAIPITSSEHTQPITDISGTFRAIFNNQDKDIFYVQKFENDNWRTKYEAEFKAKCIADFDKNIKYNQTHPDSIFVQHLLITMPQSFDRATMSENHLTLTKAKDGISEKLAVTKDNYQHFLKTYFGLDVTINRIENSDSKS
>LR134090.1|VDZ28966.1|2828273_2829290_+|nickel-transport-protein
MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEVDALLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTLDGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFISSIEFDYLGYILVALFLITWLISSLIWKFGRIEHKWSK
>LR134090.1|VDZ28965.1|2827533_2828109_+|DNA-binding-protein
MTLPKIGKPATRALNSQGIYTLEAVSQYTKSSLMEMHGVGPKAISILEQALFQHQLHFKTEVHSSLPFLLTGDVSCNHAPKRQQMIDFIVATAALDIELLRSLVTTEFIWSVPGRFDIYGPQILIQELSNHYKEIASLNIQSIITHGCLGSMHGIEILKTGKEIHFAHFFEFENHKKDAKLSKVTSYIVVG
>LR134090.1|VDZ28975.1|2837386_2838226_-|Chromosome-(plasmid)-partitioning-protein-ParB
MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR
>LR134090.1|VDZ28976.1|2838268_2838988_-|Ribosomal-RNA-small-subunit-methyltransferase-G
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHNVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>LR134090.1|VDZ28977.1|2838987_2840865_-|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA
MAQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDVVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>LR134090.1|VDZ28978.1|2840931_2842311_-|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGNTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>LR134090.1|VDZ28979.1|2842453_2842801_-|ribonuclease-P-protein-component
MEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>LR134090.1|VDZ28980.1|2842927_2843065_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	802203-802220	0	1.0
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	1787420-1787437	0	1.0
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	2505953-2505970	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	637448-637478	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	834748-834778	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	834806-834836	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1044274-1044304	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1502515-1502545	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1502572-1502602	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1502630-1502660	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1578048-1578078	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	2381640-2381670	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	2400776-2400806	0	1.0
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	2837062-2837092	0	1.0
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	637483-637508	0	1.0
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	1301598-1301623	0	1.0
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	2400926-2400951	0	1.0
LR134090_2	2.1\|883023\|39\|LR134090\|PILER-CR	883023-883061	39	LR134090.1	550302-550340	1	0.974
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	1138487-1138504	1	0.944
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	882921-882951	1	0.968
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1301630-1301660	1	0.968
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	2837120-2837150	1	0.968
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	2200292-2200317	1	0.962
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	52853-52888	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	142363-142398	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	550188-550223	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	637501-637536	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	1301570-1301605	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	2140901-2140936	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	2400888-2400923	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	2400944-2400979	2	0.944
LR134090_2	2.2\|883082\|36\|LR134090\|PILER-CR	883082-883117	36	LR134090.1	2535284-2535319	2	0.944
LR134090_8	8.1\|2366185\|18\|LR134090\|CRT	2366185-2366202	18	LR134090.1	891657-891674	2	0.889
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	467486-467503	2	0.889
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	679139-679156	2	0.889
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	1193613-1193630	2	0.889
LR134090_8	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	LR134090.1	2000892-2000909	2	0.889
LR134090_8	8.3\|2366303\|19\|LR134090\|CRT	2366303-2366321	19	LR134090.1	1281964-1281982	2	0.895
LR134090_8	8.3\|2366303\|19\|LR134090\|CRT	2366303-2366321	19	LR134090.1	1529394-1529412	2	0.895
LR134090_8	8.3\|2366303\|19\|LR134090\|CRT	2366303-2366321	19	LR134090.1	1787307-1787325	2	0.895
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	550304-550334	2	0.935
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	948232-948262	2	0.935
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1193592-1193622	2	0.935
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	LR134090.1	1282028-1282058	2	0.935
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	1281929-1281954	2	0.923
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	1281952-1281977	2	0.923
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	2400870-2400895	2	0.923
LR134090_11	11.1\|2836973\|26\|LR134090\|CRISPRCasFinder	2836973-2836998	26	LR134090.1	2535312-2535337	2	0.923

1. spacer 8.2|2366244|18|LR134090|CRT matches to position: 802203-802220, mismatch: 0, identity: 1.0

ctttttgaaattctctat	CRISPR spacer
ctttttgaaattctctat	Protospacer
******************

2. spacer 8.2|2366244|18|LR134090|CRT matches to position: 1787420-1787437, mismatch: 0, identity: 1.0

ctttttgaaattctctat	CRISPR spacer
ctttttgaaattctctat	Protospacer
******************

3. spacer 8.2|2366244|18|LR134090|CRT matches to position: 2505953-2505970, mismatch: 0, identity: 1.0

ctttttgaaattctctat	CRISPR spacer
ctttttgaaattctctat	Protospacer
******************

4. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 637448-637478, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

5. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 834748-834778, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

6. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 834806-834836, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

7. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1044274-1044304, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

8. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1502515-1502545, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

9. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1502572-1502602, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

10. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1502630-1502660, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

11. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1578048-1578078, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

12. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 2381640-2381670, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

13. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 2400776-2400806, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

14. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 2837062-2837092, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

15. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 637483-637508, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

16. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 1301598-1301623, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

17. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 2400926-2400951, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

18. spacer 2.1|883023|39|LR134090|PILER-CR matches to position: 550302-550340, mismatch: 1, identity: 0.974

gatttcgaaaagaaattctacaaacaatgcaagttgggg	CRISPR spacer
gatttcgaaaagaaattctacagacaatgcaagttgggg	Protospacer
**********************.****************

19. spacer 8.2|2366244|18|LR134090|CRT matches to position: 1138487-1138504, mismatch: 1, identity: 0.944

ctttttgaaattctctat	CRISPR spacer
cttttcgaaattctctat	Protospacer
*****.************

20. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 882921-882951, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcactgcctgtagaatttcttttcgaaa	Protospacer
******.************************

21. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1301630-1301660, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttcttttcgaaa	Protospacer
**.****************************

22. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 2837120-2837150, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttcttttcgaaa	Protospacer
**.****************************

23. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 2200292-2200317, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

24. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 52853-52888, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

25. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 142363-142398, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

26. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 550188-550223, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctgtcggaaagtcagcatacaataatgtgcaagtt	Protospacer
**** ******* ***********************

27. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 637501-637536, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

28. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 1301570-1301605, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

29. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 2140901-2140936, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

30. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 2400888-2400923, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

31. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 2400944-2400979, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

32. spacer 2.2|883082|36|LR134090|PILER-CR matches to position: 2535284-2535319, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

33. spacer 8.1|2366185|18|LR134090|CRT matches to position: 891657-891674, mismatch: 2, identity: 0.889

acttttgtcagcttctgt	CRISPR spacer
acctttgtcagcttcagt	Protospacer
**.************ **

34. spacer 8.2|2366244|18|LR134090|CRT matches to position: 467486-467503, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
cttttttaaattctccat	Protospacer
****** ********.**

35. spacer 8.2|2366244|18|LR134090|CRT matches to position: 679139-679156, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
cttttcgaaattctttat	Protospacer
*****.********.***

36. spacer 8.2|2366244|18|LR134090|CRT matches to position: 1193613-1193630, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
cttttcgaaattctccat	Protospacer
*****.*********.**

37. spacer 8.2|2366244|18|LR134090|CRT matches to position: 2000892-2000909, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
ctttttgaagttctatat	Protospacer
*********.**** ***

38. spacer 8.3|2366303|19|LR134090|CRT matches to position: 1281964-1281982, mismatch: 2, identity: 0.895

acttgctgtcagcttctat	CRISPR spacer
actttccgtcagcttctat	Protospacer
**** *.************

39. spacer 8.3|2366303|19|LR134090|CRT matches to position: 1529394-1529412, mismatch: 2, identity: 0.895

acttgctgtcagcttctat	CRISPR spacer
acttactgtcaccttctat	Protospacer
****.****** *******

40. spacer 8.3|2366303|19|LR134090|CRT matches to position: 1787307-1787325, mismatch: 2, identity: 0.895

acttgctgtcagcttctat	CRISPR spacer
actttctgccagcttctat	Protospacer
**** ***.**********

41. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 550304-550334, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgtctgtagaatttcttttcgaaa	Protospacer
**.******.*********************

42. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 948232-948262, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcttgtagaatttcttttcgaaa	Protospacer
**.*******.********************

43. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1193592-1193622, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgtctgtagaatttcttttcgaaa	Protospacer
**.******.*********************

44. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to position: 1282028-1282058, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttctttacgaaa	Protospacer
**.********************** *****

45. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 1281929-1281954, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctgtgttggggccccg	Protospacer
***.********.*************

46. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 1281952-1281977, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctatgttgggaccccg	Protospacer
***.****************.*****

47. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 2400870-2400895, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttgcggccccg	Protospacer
************.***** *******

48. spacer 11.1|2836973|26|LR134090|CRISPRCasFinder matches to position: 2535312-2535337, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagctactgtgttggggccccg	Protospacer
********* **.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134090_5	5.1\|1060453\|29\|LR134090\|CRISPRCasFinder	1060453-1060481	29	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	703321-703349	6	0.793
LR134090_10	10.1\|2807647\|31\|LR134090\|CRISPRCasFinder	2807647-2807677	31	NZ_CP009619	Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence	270870-270900	8	0.742

1. spacer 5.1|1060453|29|LR134090|CRISPRCasFinder matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 6, identity: 0.793

taaaagagggatacttgcgctgagcgcat	CRISPR spacer
gatcaaagggttccttgcgctgagcgcat	Protospacer
 *  *.**** * ****************

2. spacer 10.1|2807647|31|LR134090|CRISPRCasFinder matches to NZ_CP009619 (Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
gctgcattacctgtagcatttcttttttcaa	Protospacer
 ..*****.******* *********.  **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

317349 : 360129

Staphylococcus_phage(68.18%)

protease,holin,integrase,tail,terminase,portal,head,capsid

attL 317238:317256|attR 362299:362317

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
317238:317256	attL	NA	NA	NA	NA
VDZ24386.1\|317349_318555_-\|integrase	phage integrase family protein	A0A1X9H094	Staphylococcus_phage	6.3e-217	97.3
VDZ24388.1\|318682_319297_+	phi PVL ORF 30-like protein	A7TW88	Staphylococcus_phage	6.7e-106	99.0
VDZ24390.1\|319293_319419_-	ORF136	A0A2I6PF02	Staphylococcus_phage	5.1e-13	100.0
VDZ24393.1\|319497_319683_-	phage protein	A0A2I6PDS4	Staphylococcus_phage	2.5e-24	95.1
VDZ24395.1\|319679_319826_-	phage protein	U5U441	Staphylococcus_phage	4.3e-19	100.0
VDZ24403.1\|319837_320554_-	repressor-like protein	Q9G039	Staphylococcus_virus	1.0e-129	98.7
VDZ24405.1\|320717_320960_+	phage DNA-binding protein	Q9G038	Staphylococcus_virus	2.8e-39	100.0
VDZ24408.1\|320975_321773_+	prophage L54a, antirepressor	Q9MBT0	Staphylococcus_prophage	3.3e-145	99.2
VDZ24410.1\|321788_321965_+	Uncharacterised protein	B7T0F9	Staphylococcus_virus	8.8e-27	100.0
VDZ24412.1\|321961_322192_-	phiSLT ORF78-like protein	A0A0H3U2T9	Staphylococcus_phage	9.4e-37	100.0
VDZ24414.1\|322246_322534_+	Uncharacterised protein	NA	NA	NA	NA
VDZ24417.1\|322481_322724_-	Uncharacterised protein	Q4ZCA7	Staphylococcus_virus	3.6e-15	50.0
VDZ24419.1\|322784_323537_+	antirepressor	S4SW96	Staphylococcus_phage	1.1e-137	98.8
VDZ24421.1\|323552_323750_+	phage protein	A7TWF5	Staphylococcus_phage	3.3e-22	93.8
VDZ24424.1\|323736_324117_-	phage protein	Q4ZCQ5	Staphylococcus_virus	3.8e-67	99.2
VDZ24426.1\|324469_324733_+	DNA-binding protein	B7T0G2	Staphylococcus_virus	4.1e-44	96.6
VDZ24428.1\|324745_324913_+	phage protein	Q9MBS6	Staphylococcus_prophage	2.3e-21	98.2
VDZ24430.1\|324913_325234_+	Uncharacterised protein	Q9MBS5	Staphylococcus_prophage	1.6e-55	100.0
VDZ24433.1\|325325_325586_+	phage protein	Q9MBS4	Staphylococcus_prophage	1.5e-43	100.0
VDZ24435.1\|325595_325817_+	phage protein	B2ZYV2	Staphylococcus_phage	3.2e-34	100.0
VDZ24437.1\|325809_326433_+	putative phage topoisomerase	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
VDZ24440.1\|326432_326852_+	prophage L54a, single-stranded DNA binding protein	Q4ZA54	Staphylococcus_virus	1.4e-62	100.0
VDZ24442.1\|326865_327540_+	phage protein	Q4ZAK7	Staphylococcus_virus	1.2e-127	97.8
VDZ24444.1\|327532_328288_+	hypothetical phage-related protein	C8CGZ1	Staphylococcus_phage	3.3e-131	92.8
VDZ24447.1\|328287_328644_+	phage protein	M9NS37	Staphylococcus_phage	8.2e-64	100.0
VDZ24449.1\|328640_329882_+	prophage L54a, replicative DNA helicase	A0A0E3T8L1	Staphylococcus_phage	4.5e-226	98.5
VDZ24451.1\|329878_330094_+	hypothetical phage-related protein	A9CR72	Staphylococcus_phage	6.3e-35	98.6
VDZ24453.1\|330096_330321_+	putative phi ETA-like protein	A0A059T665	Staphylococcus_phage	3.5e-36	98.6
VDZ24456.1\|330331_330736_+	hypothetical phage-related protein	Q4ZDX8	Staphylococcus_virus	8.7e-70	97.8
VDZ24458.1\|330740_330926_+	phage protein	A0A2I6PDN7	Staphylococcus_phage	3.5e-26	96.7
VDZ24460.1\|330926_331232_+	Uncharacterised protein	Q4ZA45	Staphylococcus_virus	2.2e-49	100.0
VDZ24463.1\|331359_331719_+	PVL ORF-50-like family	B2ZYW3	Staphylococcus_phage	2.5e-60	98.3
VDZ24466.1\|331719_331968_+	phage family protein	A0A2I6PDI0	Staphylococcus_phage	1.5e-40	96.3
VDZ24469.1\|331981_332392_+	putative phage PVL protein	A0A1P8CN10	Staphylococcus_phage	6.1e-47	68.4
VDZ24472.1\|332391_332667_+	Phage protein	Q4ZA41	Staphylococcus_virus	1.3e-45	100.0
VDZ24475.1\|332659_332908_+	Phage protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
VDZ24477.1\|332900_333437_+	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	1.4e-94	99.4
VDZ24480.1\|333473_333758_+	Uncharacterised protein	NA	NA	NA	NA
VDZ24483.1\|333774_333981_+	Uncharacterised protein	NA	NA	NA	NA
VDZ24486.1\|333977_334184_+	phage protein	Q4ZCV6	Staphylococcus_virus	7.1e-20	98.5
VDZ24489.1\|334180_334333_+	transcriptional activator rinB-like protein	B7T0I1	Staphylococcus_virus	1.2e-19	98.0
VDZ24492.1\|334400_334601_+	putative exported phage protein	A0A2I6PEG6	Staphylococcus_phage	1.6e-24	95.5
VDZ24495.1\|334649_335021_+	E family protein	A0A2I6PF19	Staphylococcus_phage	3.8e-64	100.0
VDZ24497.1\|335094_335532_+	phage regulatory protein	A0A2I6PEN3	Staphylococcus_phage	4.3e-75	98.6
VDZ24499.1\|335688_336003_+	HNH endonuclease family protein	M9QQL5	Staphylococcus_phage	2.5e-56	100.0
VDZ24502.1\|336203_336437_+\|terminase	Phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	8.0e-36	98.7
VDZ24504.1\|336426_338118_+\|terminase	terminase large subunit	Q4ZD20	Staphylococcus_virus	0.0e+00	99.1
VDZ24506.1\|338122_339361_+\|portal	portal protein	A0A2I6PER5	Staphylococcus_phage	7.6e-234	99.5
VDZ24509.1\|339344_340118_+\|protease	phage protease	A0A2I6PEQ7	Staphylococcus_phage	3.9e-135	98.4
VDZ24511.1\|340129_341293_+\|capsid	putative phage capsid protein	A0A2I6PDD7	Staphylococcus_phage	1.5e-215	99.0
VDZ24513.1\|341361_341640_+\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PEQ1	Staphylococcus_phage	6.0e-46	98.9
VDZ24515.1\|341651_341984_+	phage protein	M9QX19	Staphylococcus_phage	2.4e-57	99.1
VDZ24518.1\|341980_342382_+	putative phiSLT protein	A0A0K1LL98	Staphylococcus_phage	1.1e-67	100.0
VDZ24520.1\|342382_342778_+	phage protein	A0A0K1LKC0	Staphylococcus_phage	1.5e-66	99.2
VDZ24522.1\|342812_343454_+\|tail	major tail protein	A0A2I6PEP6	Staphylococcus_phage	1.8e-117	98.1
VDZ24525.1\|343545_344001_+\|tail	major tail protein	Q9B0D4	Staphylococcus_phage	1.2e-75	98.0
VDZ24528.1\|344058_344409_+	putative gp48	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
VDZ24530.1\|344450_344609_+	putative gp49	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
VDZ24532.1\|344622_350823_+	TP901 family prophage L54a	A0A0K1LKC4	Staphylococcus_phage	0.0e+00	98.6
VDZ24535.1\|350822_351647_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.6e-158	99.6
VDZ24538.1\|351655_353239_+\|tail	prophage endopeptidase tail family protein	Q4ZD01	Staphylococcus_virus	1.3e-305	99.1
VDZ24540.1\|353238_353529_+	putative gp53	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
VDZ24542.1\|353544_355455_+	putative minor structural protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	99.4
VDZ24544.1\|355454_356921_+\|tail	putative phage tail protein	A0A2I6PDQ5	Staphylococcus_phage	1.8e-250	97.5
VDZ24547.1\|356920_357310_+	phage-like protein	Q4ZCZ7	Staphylococcus_virus	6.4e-62	96.9
VDZ24549.1\|357302_357467_+	phage protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
VDZ24551.1\|357512_357812_+	hypothetical phage-related protein	M9QRV2	Staphylococcus_phage	2.2e-30	98.0
VDZ24554.1\|358360_358663_+\|holin	holin	B7T0L0	Staphylococcus_virus	3.8e-46	94.0
VDZ24556.1\|358674_360129_+	amidase	A0A0N6WMR3	Staphylococcus_phage	1.4e-279	95.9
362299:362317	attR	NA	NA	NA	NA

DBSCAN-SWA_2

425301 : 442071

Staphylococcus_phage(30.77%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ24745.1\|425301_426768_+	Inosine-5-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
VDZ24748.1\|426792_428334_+	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	1.2e-23	32.6
VDZ24751.1\|428427_429564_-	Integrase	A0A1S5S7K9	Streptococcus_phage	1.0e-75	42.5
VDZ24754.1\|429647_430433_-	transcriptional regulator	A0A1S5S8T5	Streptococcus_phage	1.2e-09	58.6
VDZ24757.1\|430549_430777_+	phage protein	NA	NA	NA	NA
VDZ24760.1\|430822_431083_+	pathogenicity island protein	NA	NA	NA	NA
VDZ24763.1\|431129_431276_+	pathogenicity island protein	NA	NA	NA	NA
VDZ24765.1\|431493_431787_+	pathogenicity island protein	A0A1W6JQH0	Staphylococcus_phage	1.7e-14	46.1
VDZ24768.1\|431877_434241_+	primase	A0A2H4JCU9	uncultured_Caudovirales_phage	1.3e-136	39.1
VDZ24771.1\|434662_435007_+	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	4.2e-41	65.2
VDZ24774.1\|435231_435438_+	pathogenicity island protein	NA	NA	NA	NA
VDZ24777.1\|435424_436483_+	pahtogenicity island protein	A0A0K2CZ99	Paenibacillus_phage	3.9e-13	25.4
VDZ24780.1\|436665_437157_+	pathogenicity island protein	A0A2H4JB26	uncultured_Caudovirales_phage	2.3e-24	40.5
VDZ24783.1\|437463_438168_-	toxic shock syndrome toxin-1	NA	NA	NA	NA
VDZ24785.1\|438628_438979_+	pathogenicity island protein	A0A2H4JAH5	uncultured_Caudovirales_phage	1.8e-18	62.4
VDZ24788.1\|439097_439610_+	pathogenicity island protein	Q4ZE83	Staphylococcus_phage	5.5e-69	99.4
VDZ24791.1\|440381_441182_+	enterotoxin C-bovine	A0A097PAT7	Streptococcus_pyogenes_phage	3.1e-50	45.0
VDZ24794.1\|441348_442071_-	staphylococcal enterotoxin L	A0A1X9H080	Staphylococcus_phage	2.8e-26	34.9

DBSCAN-SWA_3

766649 : 774470

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ25618.1\|766649_767705_-	Sensor histidine protein kinase SaeS (exoprotein expression protein S)	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
VDZ25620.1\|767704_768391_-	Response regulator SaeR	NA	NA	NA	NA
VDZ25623.1\|768365_768839_-	DoxX family protein	NA	NA	NA	NA
VDZ25626.1\|769181_769622_-	lipoprotein	NA	NA	NA	NA
VDZ25629.1\|769901_770486_-	Uncharacterised protein	NA	NA	NA	NA
VDZ25631.1\|770584_771298_-	Queuosine Biosynthesis QueE Radical SAM	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
VDZ25634.1\|771301_771721_-	6-pyruvoyl-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
VDZ25637.1\|771722_772391_-	Queuosine Biosynthesis QueC ATPase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
VDZ25639.1\|772741_773335_+	Para-aminobenzoate synthase, amidotransferase component PabAb	A0A0P0IKJ1	Acinetobacter_phage	5.8e-38	42.9
VDZ25641.1\|773318_774470_+	Para-aminobenzoate synthetase component I	S4VNU7	Pandoravirus	9.2e-24	36.5

DBSCAN-SWA_4

786442 : 800878

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ25668.1\|786442_787501_+	histidinol-phosphate aminotransferase	A0A0H3TLT9	Faustovirus	1.1e-20	27.3
VDZ25671.1\|787898_788447_+	5'-3'-deoxyribonucleotidase, putative	NA	NA	NA	NA
VDZ25674.1\|789049_789967_-	Transcription regulator (contains diacylglycerol kinase catalytic domain)	A0A1V0SBJ0	Catovirus	1.6e-07	22.8
VDZ25677.1\|790248_791754_-	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
VDZ25680.1\|792093_792594_-	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	2.2e-51	70.8
VDZ25683.1\|792613_793480_-	Integral membrane domain protein	NA	NA	NA	NA
VDZ25686.1\|794280_794679_+	Nrdi	A0A2H4J545	uncultured_Caudovirales_phage	4.3e-53	72.7
VDZ25689.1\|794641_796747_+	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
VDZ25692.1\|796864_797836_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
VDZ25695.1\|798163_799177_+	FatD	A0A2H4IY97	uncultured_Caudovirales_phage	2.2e-138	78.0
VDZ25697.1\|799163_800120_+	Iron compound ABC uptake transporter permease protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
VDZ25700.1\|800116_800878_+	Iron compound ABC uptake transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	5.0e-18	31.6

DBSCAN-SWA_5

1045650 : 1054123

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ26391.1\|1045650_1046133_+	AIR carboxylase	A0A2P0VNU7	Tetraselmis_virus	3.4e-20	43.3
VDZ26393.1\|1046119_1047952_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	2.1e-46	41.2
VDZ26396.1\|1047951_1048215_+	Phosphoribosylformylglycinamidine synthase, PurS subunit	NA	NA	NA	NA
VDZ26398.1\|1048216_1048888_+	Phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
VDZ26400.1\|1048880_1051070_+	Phosphoribosylformylglycinamidine synthase, synthetase subunit	A6N228	Microbacterium_phage	3.0e-140	39.7
VDZ26402.1\|1051048_1052533_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
VDZ26404.1\|1052525_1053554_+	Phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.2e-61	41.1
VDZ26406.1\|1053556_1054123_+	Phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_6

1105569 : 1133745

Staphylococcus_phage(83.33%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ26506.1\|1105569_1106052_+	Phosphopantetheine adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
VDZ26508.1\|1106113_1107253_-	Putative cytosolic protein	NA	NA	NA	NA
VDZ26510.1\|1107379_1107937_+	YlbN-like protein	NA	NA	NA	NA
VDZ26512.1\|1108016_1108190_+	50S ribosomalprotein L32p	NA	NA	NA	NA
VDZ26514.1\|1108219_1108600_-	arsenate reductase, putative	A0A2H4PQT9	Staphylococcus_phage	1.0e-56	98.1
VDZ26516.1\|1108617_1109910_-	arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	2.6e-224	97.4
VDZ26518.1\|1109909_1110224_-	arsenical resistance operon repressor 2	A0A2H4PQT4	Staphylococcus_phage	1.3e-52	98.1
VDZ26520.1\|1110745_1112245_+	pyridine nucleotide-disulfide oxidoreductase family protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
VDZ26522.1\|1112728_1113772_+	5-amino-6-(5-phosphoribosylamino)uracil reductase	A0A2H4PQS8	Staphylococcus_phage	9.1e-196	98.8
VDZ26524.1\|1113778_1114411_+	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
VDZ26526.1\|1114421_1115603_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
VDZ26528.1\|1115615_1116080_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
VDZ26530.1\|1116219_1117008_-	insertion element protein	A0A0C5AEA5	Paenibacillus_phage	5.7e-49	51.4
VDZ26532.1\|1117031_1117760_-\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0
VDZ26534.1\|1117864_1118866_-	Proline dehydrogenase (Proline oxidase)	A0A2H4PQT6	Staphylococcus_phage	2.0e-184	99.4
VDZ26536.1\|1119099_1119927_+	Lysophospholipase; Monoglyceride lipase; putative	NA	NA	NA	NA
VDZ26538.1\|1120497_1120899_+	HTH-type transcriptional regulator rot	NA	NA	NA	NA
VDZ26540.1\|1121018_1121582_-	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
VDZ26542.1\|1121578_1122532_-	Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
VDZ26544.1\|1122641_1123823_+	Multidrug resistance protein	A0A2H4PQR6	Staphylococcus_phage	4.7e-217	99.2
VDZ26546.1\|1124110_1126528_+\|tRNA	Leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.8
VDZ26548.1\|1126549_1126861_+	Rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
VDZ26550.1\|1127187_1133745_+	LPXTG-motif cell wall anchor domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	5.5e-307	96.7

DBSCAN-SWA_7

1257827 : 1266870

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ26755.1\|1257827_1258832_+	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
VDZ26756.1\|1258833_1259859_+\|tRNA	S-adenosylmethionine--tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
VDZ26757.1\|1259881_1261021_+\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
VDZ26758.1\|1261039_1261300_+	Preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
VDZ26760.1\|1261574_1263854_+	Protein-export membrane protein secD / Protein-export membrane protein secF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
VDZ26761.1\|1264056_1266330_+	Single-stranded-DNA-specific exonuclease recJ	A7KV88	Bacillus_phage	1.1e-63	29.3
VDZ26762.1\|1266351_1266870_+	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_8

1336277 : 1344589

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ26884.1\|1336277_1338077_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0
VDZ26886.1\|1338300_1339407_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
VDZ26888.1\|1339537_1340215_+\|tRNA	Putative tRNA-m1A22 methylase	NA	NA	NA	NA
VDZ26890.1\|1340217_1341318_+	NIF3 protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
VDZ26892.1\|1341431_1342778_+	ATP-dependent RNA helicase YqfR	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
VDZ26894.1\|1342787_1343678_+	endonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
VDZ26896.1\|1343803_1344589_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-18	27.9

DBSCAN-SWA_9

1810913 : 1950984

168

Staphylococcus_phage(60.87%)

tRNA,protease,holin,transposase,integrase,tail,terminase,bacteriocin,head,capsid

attL 1891544:1891564|attR 1946547:1946567

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ27701.1\|1810913_1813316_-\|tRNA	Phenylalanyl-tRNA synthetase beta chain	NA	NA	NA	NA
VDZ27703.1\|1813315_1814374_-\|tRNA	Phenylalanyl-tRNA synthetase alpha chain	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
VDZ27705.1\|1814754_1815495_-	SpoU rRNA Methylase family protein	NA	NA	NA	NA
VDZ27707.1\|1815877_1816201_-	heme-degrading monooxygenase isdG	NA	NA	NA	NA
VDZ27709.1\|1816219_1816954_-	NPQTN specific sortase B	NA	NA	NA	NA
VDZ27711.1\|1817015_1817984_-	iron/heme permease	NA	NA	NA	NA
VDZ27713.1\|1817993_1818872_-	Heme transporter IsdDEF, lipoprotein IsdE	NA	NA	NA	NA
VDZ27715.1\|1818868_1819945_-	Heme transporter IsdDEF, membrane component IsdD	NA	NA	NA	NA
VDZ27717.1\|1819944_1820628_-	surface anchored protein	NA	NA	NA	NA
VDZ27719.1\|1820836_1821901_+	iron-regulated heme-iron binding protein	NA	NA	NA	NA
VDZ27721.1\|1822103_1824029_+	iron-regulated cell wall-anchored protein	NA	NA	NA	NA
VDZ27723.1\|1824263_1825202_-	Abortive infection bacteriophage resistance protein	A0A059NT88	Lactococcus_phage	6.7e-73	44.3
VDZ27725.1\|1825536_1826982_-	N-acetylmuramoyl-L-alanine amidase family protein	A0A059T7Q7	Staphylococcus_phage	5.7e-289	97.1
VDZ27727.1\|1826962_1827400_-\|holin	holin, phage phi LC3 family	A7YGY0	Staphylococcus_virus	5.9e-72	97.2
VDZ27729.1\|1827450_1829463_-\|tail	phage-related tail fiber	Q4ZA81	Staphylococcus_virus	0.0e+00	96.3
VDZ27731.1\|1829475_1831380_-	phage-related cell wall hydrolase	B7T0E8	Staphylococcus_virus	0.0e+00	98.4
VDZ27733.1\|1831516_1831822_-	phage protein	A0A059T679	Staphylococcus_phage	5.2e-43	100.0
VDZ27735.1\|1831861_1832044_-	phage protein	Q4ZA85	Staphylococcus_virus	4.3e-29	100.0
VDZ27737.1\|1832044_1832422_-	phage-like protein	Q4ZA86	Staphylococcus_virus	2.6e-60	99.2
VDZ27739.1\|1832421_1834245_-	phiETA ORF57-like protein	Q4ZA88	Staphylococcus_virus	0.0e+00	98.5
VDZ27741.1\|1834244_1836155_-	Putative major teichoic acid biosynthesis protein C	B7T0E3	Staphylococcus_virus	0.0e+00	97.8
VDZ27743.1\|1836169_1838071_-\|tail	prophage endopeptidase tail family protein	B7T0E2	Staphylococcus_virus	0.0e+00	97.0
VDZ27745.1\|1838079_1839027_-	phi 11 orf43	Q8SDT6	Staphylococcus_phage	8.9e-182	99.0
VDZ27747.1\|1839039_1842504_-	phage tape measure protein	S4V989	Staphylococcus_phage	4.1e-261	98.2
VDZ27749.1\|1842520_1842865_-	phi 11 orf41	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
VDZ27751.1\|1842894_1843260_-	phi 11 orf40	A0A0F6N4J9	Staphylococcus_phage	3.6e-59	100.0
VDZ27753.1\|1843321_1843903_-\|tail	phage major tail protein, TP901-1 family; phi 11 orf39	B7T0D7	Staphylococcus_virus	3.1e-105	100.0
VDZ27755.1\|1843920_1844304_-	phi 11 orf38	B7T0D6	Staphylococcus_virus	3.5e-68	100.0
VDZ27757.1\|1844315_1844663_-	phi 11 orf37	B7T0D5	Staphylococcus_virus	2.4e-60	100.0
VDZ27759.1\|1844662_1844965_-	phage-like protein	A4ZFB6	Staphylococcus_virus	1.7e-49	96.0
VDZ27761.1\|1844961_1845294_-	phi 11 orf36	B7T0D4	Staphylococcus_virus	1.6e-53	99.1
VDZ27763.1\|1845302_1845590_-	phage-like protein	B7T0D3	Staphylococcus_virus	3.8e-43	92.6
VDZ27765.1\|1845611_1846586_-\|capsid,head	Phage head protein/Phage major capsid protein	E0Y3L0	Staphylococcus_virus	1.7e-180	98.8
VDZ27767.1\|1846599_1847220_-	phi 11 orf33	B2ZYY4	Staphylococcus_phage	3.0e-69	94.2
VDZ27769.1\|1847328_1847499_-	Uncharacterised protein	Q4ZDF2	Staphylococcus_virus	3.3e-23	100.0
VDZ27771.1\|1847571_1848567_-\|head	phage putative head morphogenesis protein, SPP1 gp7 family Mu50B	E0Y3K7	Staphylococcus_virus	9.9e-184	99.7
VDZ27773.1\|1848573_1850109_-	phage-like protein	Q4ZDN2	Staphylococcus_virus	3.4e-284	96.9
VDZ27775.1\|1850119_1851409_-\|terminase	phage-associated terminase large subunit	B7T0C6	Staphylococcus_virus	1.2e-253	98.6
VDZ27777.1\|1851411_1851906_-\|terminase	Phage terminase, small subunit	B7T0C5	Staphylococcus_virus	6.6e-88	98.8
VDZ27779.1\|1852093_1852516_-	phage transcriptional activator RinA	S4V7K2	Staphylococcus_phage	3.0e-73	97.1
VDZ27781.1\|1852539_1852686_-	phage protein	A0A059T5A8	Staphylococcus_phage	3.7e-15	97.9
VDZ27783.1\|1852686_1853052_-	phage protein	I1W652	Staphylococcus_phage	4.8e-59	99.2
VDZ27785.1\|1853052_1853226_-	int gene activator RinB	Q4ZBK0	Staphylococcus_phage	3.5e-20	93.0
VDZ27787.1\|1853222_1853429_-	Protein of uncharacterised function (DUF1381)	B7T0C2	Staphylococcus_virus	6.0e-19	95.6
VDZ27789.1\|1853425_1853632_-	Uncharacterised protein	NA	NA	NA	NA
VDZ27791.1\|1853648_1853933_-	Uncharacterised protein	NA	NA	NA	NA
VDZ27793.1\|1853969_1854506_-	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	1.4e-94	99.4
VDZ27795.1\|1854498_1854747_-	Phage protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
VDZ27797.1\|1854739_1855024_-	phage protein	A0A2I6PE24	Staphylococcus_phage	1.3e-24	63.8
VDZ27799.1\|1855020_1855458_-	phage protein	NA	NA	NA	NA
VDZ27801.1\|1855454_1855865_-	putative phage PVL protein	Q4ZA42	Staphylococcus_virus	5.5e-72	99.3
VDZ27803.1\|1855875_1856124_-	phage family protein	S4V683	Staphylococcus_phage	5.2e-41	97.6
VDZ27805.1\|1856124_1856484_-	PVL ORF-50-like family	B2ZYW3	Staphylococcus_phage	2.5e-60	98.3
VDZ27807.1\|1856611_1856917_-	Uncharacterised protein	Q4ZA45	Staphylococcus_virus	6.4e-49	99.0
VDZ27809.1\|1856917_1857103_-	Protein of uncharacterised function (DUF3113)	Q4ZA46	Staphylococcus_virus	4.1e-27	100.0
VDZ27811.1\|1857107_1857512_-	hypothetical phage-related protein	A7TWN5	Staphylococcus_phage	6.6e-70	97.8
VDZ27813.1\|1857522_1857747_-	putative phi ETA-like protein	A0A059T665	Staphylococcus_phage	3.5e-36	98.6
VDZ27815.1\|1857759_1857918_-	Uncharacterised protein	A0A2I6PDX0	Staphylococcus_phage	4.5e-22	98.1
VDZ27817.1\|1857914_1858700_-	ORF017	A0A0H4J332	Staphylococcus_phage	1.9e-145	100.0
VDZ27819.1\|1858712_1859474_-	Conserved phage C-terminus (Phg_2220_C)	A0A2I6PDW4	Staphylococcus_phage	2.5e-118	97.2
VDZ27821.1\|1859535_1859946_+	Uncharacterised protein	Q4ZDQ7	Staphylococcus_virus	4.2e-72	99.3
VDZ27823.1\|1859800_1860130_-	Uncharacterised protein	Q4ZDQ8	Staphylococcus_virus	5.3e-49	93.6
VDZ27825.1\|1860131_1860800_-	phage protein	Q4ZAK7	Staphylococcus_virus	7.5e-127	97.7
VDZ27827.1\|1860813_1861233_-	prophage L54a, single-stranded DNA binding protein	Q4ZA54	Staphylococcus_virus	1.4e-62	100.0
VDZ27829.1\|1861232_1861856_-	putative phage topoisomerase	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
VDZ27831.1\|1861848_1862070_-	phage protein	B2ZYV2	Staphylococcus_phage	3.2e-34	100.0
VDZ27833.1\|1862079_1862340_-	phage protein	Q9MBS4	Staphylococcus_prophage	1.5e-43	100.0
VDZ27835.1\|1862431_1862752_-	Uncharacterised protein	Q9MBS5	Staphylococcus_prophage	1.6e-55	100.0
VDZ27837.1\|1862752_1862920_-	phage protein	Q9MBS6	Staphylococcus_prophage	4.4e-20	94.5
VDZ27839.1\|1862903_1863041_-	Uncharacterised protein	Q4ZA61	Staphylococcus_virus	2.0e-15	95.6
VDZ27841.1\|1863100_1863331_+	phage protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
VDZ27843.1\|1863305_1863482_-	phi PV83 orf 10-like protein	S4SVC9	Staphylococcus_phage	2.4e-24	96.6
VDZ27845.1\|1863497_1864253_-	anti repressor	A0A0H4J326	Staphylococcus_phage	9.6e-139	99.2
VDZ27847.1\|1864309_1864522_+	Uncharacterised protein	NA	NA	NA	NA
VDZ27849.1\|1864511_1864655_-	phage protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
VDZ27851.1\|1864670_1864889_-	helix-turn-helix family protein	Q8SDX1	Staphylococcus_phage	2.9e-35	100.0
VDZ27853.1\|1865030_1865750_+	putative phage repressor protein	A0A1X9H038	Staphylococcus_phage	9.0e-94	76.0
VDZ27855.1\|1865767_1866493_+	phage protein	Q4ZA70	Staphylococcus_virus	6.9e-126	100.0
VDZ27857.1\|1866524_1866962_+	Uncharacterised protein	Q4ZA71	Staphylococcus_virus	3.3e-75	100.0
VDZ27859.1\|1866955_1867363_+	MTH538 TIR-like domain (DUF1863)	Q4ZA72	Staphylococcus_virus	2.9e-73	100.0
VDZ27861.1\|1867359_1867557_-	Uncharacterised protein	Q4ZA73	Staphylococcus_virus	1.5e-30	100.0
VDZ27863.1\|1867666_1869052_+\|integrase	integrase	Q4ZA74	Staphylococcus_virus	3.6e-264	100.0
VDZ27865.1\|1869503_1870358_-	peptidoglycan endo-beta-N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
VDZ27867.1\|1870633_1870858_-	putative staphylococcal protein	NA	NA	NA	NA
VDZ27869.1\|1871056_1871527_+	RNA polymerase sigma factor sigS	A0A2H4PQT5	Staphylococcus_phage	4.8e-80	96.8
VDZ27871.1\|1871639_1872083_+	comK family protein	NA	NA	NA	NA
VDZ27873.1\|1872069_1872513_-	putative staphylococcal protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
VDZ27875.1\|1872810_1873446_+\|protease	CAAX amino terminal protease	NA	NA	NA	NA
VDZ27877.1\|1873882_1874596_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
VDZ27878.1\|1874853_1875156_+	membrane protein	NA	NA	NA	NA
VDZ27880.1\|1875411_1875777_+	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	2.4e-58	97.5
VDZ27882.1\|1875773_1876127_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.2e-20	94.0
VDZ27884.1\|1876376_1877210_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	6.0e-158	99.3
VDZ27886.1\|1877421_1878330_-	Uncharacterised protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
VDZ27888.1\|1878454_1879648_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
VDZ27890.1\|1880018_1881611_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
VDZ27892.1\|1881905_1882676_-	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	2.0e-139	96.8
VDZ27894.1\|1882656_1883136_-	phosphohydrolase	A0A2H4PQM4	Staphylococcus_phage	4.3e-84	98.1
VDZ27896.1\|1883195_1883453_+	Putative cytosolic protein	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
VDZ27898.1\|1883449_1884451_-	O-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.1e-185	97.0
VDZ27900.1\|1884455_1885934_-	O-succinylbenzoic acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	9.3e-279	95.9
VDZ27902.1\|1886092_1886575_-	putative lipoprotein	A0A2H4PQN7	Staphylococcus_phage	8.4e-80	99.3
VDZ27904.1\|1886886_1887501_+	endonuclease	A0A2H4PQM8	Staphylococcus_phage	3.7e-40	84.3
VDZ27906.1\|1887581_1888577_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	4.3e-70	95.6
VDZ27908.1\|1888652_1889279_+	lipoprotein	A0A2H4PQM7	Staphylococcus_phage	1.1e-79	82.2
VDZ27910.1\|1889319_1889661_+	Uncharacterised protein	A0A2H4PQN6	Staphylococcus_phage	2.3e-55	95.6
VDZ27912.1\|1889761_1890334_+	Uncharacterised protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
VDZ27914.1\|1890709_1891546_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
VDZ27916.1\|1891533_1892238_+	ABC transporter permease	NA	NA	NA	NA
1891544:1891564	attL	NA	NA	NA	NA
VDZ27918.1\|1892351_1892798_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
VDZ27920.1\|1892879_1893104_-\|transposase	transposase	NA	NA	NA	NA
VDZ27922.1\|1893920_1894295_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
VDZ27924.1\|1894284_1894665_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
VDZ27926.1\|1894872_1895313_-	putative protein with DUF1433	NA	NA	NA	NA
VDZ27928.1\|1895357_1896971_+	pathogenicity island protein	NA	NA	NA	NA
VDZ27930.1\|1896985_1897285_+	ESAT-6 family protein	NA	NA	NA	NA
VDZ27932.1\|1897521_1898700_-	Type I restriction-modification system, specificity subunit S	A0A2H4PQP5	Staphylococcus_phage	5.0e-41	35.4
VDZ27934.1\|1898692_1900249_-	Type I restriction enzyme EcoprrI M protein	A0A2H4PQP4	Staphylococcus_phage	5.7e-287	97.5
VDZ27936.1\|1900612_1901332_-\|protease	Serine protease splD	A0A2H4PQP1	Staphylococcus_phage	2.6e-125	94.6
VDZ27938.1\|1901457_1902177_-\|protease	Serine protease splC	A0A2H4PQP7	Staphylococcus_phage	5.1e-121	91.6
VDZ27940.1\|1902234_1902957_-\|protease	Serine protease splB	A0A2H4PQN0	Staphylococcus_phage	8.7e-129	96.7
VDZ27942.1\|1903081_1903411_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.2e-55	96.3
VDZ27944.1\|1903578_1903788_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	4.4e-25	92.4
VDZ27946.1\|1904752_1905316_+	beta-lactamase	A0A2H4PQH6	Staphylococcus_phage	5.6e-51	62.4
VDZ27948.1\|1905789_1906488_-	lantibiotic ABC transporter protein	A0A2H4PQH0	Staphylococcus_phage	7.1e-112	93.1
VDZ27950.1\|1906484_1907246_-	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family protein	A0A2H4PQH2	Staphylococcus_phage	2.5e-126	94.9
VDZ27952.1\|1907242_1907935_-	lantibiotic immunity protein F	A0A2H4PQG7	Staphylococcus_phage	1.4e-120	97.4
VDZ27954.1\|1907957_1909331_-\|protease	epidermin leader peptide processing serine protease EpiP	A0A2H4PQH1	Staphylococcus_phage	9.7e-246	94.5
VDZ27956.1\|1909340_1909859_-	lantibiotic modifying enzyme	A0A2H4PQG9	Staphylococcus_phage	1.9e-93	97.7
VDZ27958.1\|1909874_1911119_-	Epidermin biosynthesis protein epiC	A0A2H4PQH9	Staphylococcus_phage	1.2e-210	88.6
VDZ27960.1\|1911111_1914105_-\|bacteriocin	thiopeptide-type bacteriocin biosynthesis domain protein	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	92.3
VDZ27962.1\|1914169_1914313_-	lantibiotic protein	A0A2H4PQH4	Staphylococcus_phage	3.8e-20	100.0
VDZ27964.1\|1915077_1915866_-	insertion element protein	A0A0C5AEA5	Paenibacillus_phage	5.7e-49	51.4
VDZ27966.1\|1915889_1916618_-\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0
VDZ27968.1\|1916693_1916837_-	lantibiotic protein	A0A2H4PQH4	Staphylococcus_phage	9.9e-13	76.6
VDZ27970.1\|1917079_1917472_-	Leukotoxin LukD	A0A2H4PQH7	Staphylococcus_phage	1.8e-72	99.2
VDZ27972.1\|1917493_1918063_-	Leukotoxin LukD	A0A2H4PQH7	Staphylococcus_phage	3.1e-97	97.4
VDZ27974.1\|1918064_1918331_-	Leukocidin S subunit lukE	A0A2H4PQI5	Staphylococcus_phage	4.9e-45	100.0
VDZ27976.1\|1918463_1919000_-	Leukocidin S subunit lukE	A0A2H4PQI5	Staphylococcus_phage	9.7e-93	100.0
VDZ27978.1\|1919727_1920177_+	Uncharacterised protein	NA	NA	NA	NA
VDZ27980.1\|1920197_1920974_+	Domain of uncharacterised function DUF1828	NA	NA	NA	NA
VDZ27982.1\|1921369_1921864_+	Uncharacterised protein	NA	NA	NA	NA
VDZ27984.1\|1921939_1922989_+\|integrase	putative integrase	A0A2H4JB53	uncultured_Caudovirales_phage	1.3e-181	89.4
VDZ27986.1\|1924193_1924748_-	Putative hydrolase ydeN	NA	NA	NA	NA
VDZ27988.1\|1925066_1926467_-	Protoporphyrinogen IX oxidase, aerobic	NA	NA	NA	NA
VDZ27990.1\|1926490_1927414_-	Ferrochelatase, protoheme ferro-lyase	NA	NA	NA	NA
VDZ27992.1\|1927471_1928509_-	Uroporphyrinogen III decarboxylase	NA	NA	NA	NA
VDZ27993.1\|1928770_1929274_+	signal transduction protein	NA	NA	NA	NA
VDZ27994.1\|1929397_1930621_-	EcsB	NA	NA	NA	NA
VDZ27996.1\|1930613_1931354_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.4e-25	30.7
VDZ27998.1\|1931487_1931910_+	adenosine 5'-monophosphoramidase	NA	NA	NA	NA
VDZ28000.1\|1932051_1932417_+	gas vesicle protein-protein	NA	NA	NA	NA
VDZ28002.1\|1933148_1933706_+	membrane protein	NA	NA	NA	NA
VDZ28004.1\|1933910_1934873_+	Foldase protein PrsA precursor	NA	NA	NA	NA
VDZ28006.1\|1934993_1935935_-	CMP-binding-factor 1	NA	NA	NA	NA
VDZ28008.1\|1935931_1938868_-	membrane associated protein	NA	NA	NA	NA
VDZ28010.1\|1938857_1940054_-	DNA repair exonuclease family protein YhaO	NA	NA	NA	NA
VDZ28012.1\|1941131_1941476_-	putative transcriptional regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
VDZ28014.1\|1941544_1942669_-	membrane protein	NA	NA	NA	NA
VDZ28016.1\|1942847_1943312_-	HTH domain protein, binds to mecA promoter region	NA	NA	NA	NA
VDZ28018.1\|1943667_1944291_-	Two-component response regulator-like protein	NA	NA	NA	NA
VDZ28020.1\|1944312_1945425_-	Two-component sensor protein	NA	NA	NA	NA
VDZ28022.1\|1945587_1946409_+	ribosomal large subunit pseudouridine synthase D	NA	NA	NA	NA
VDZ28024.1\|1946859_1948245_-	Fumarate hydratase class II	NA	NA	NA	NA
1946547:1946567	attR	NA	NA	NA	NA
VDZ28026.1\|1948440_1948836_-	membrane protein	NA	NA	NA	NA
VDZ28028.1\|1949578_1949731_-	putative staphylococcal protein	NA	NA	NA	NA
VDZ28030.1\|1949755_1950355_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
VDZ28032.1\|1950513_1950984_-\|tRNA	tRNA (cytosine34-2-O-)-methyltransferase	NA	NA	NA	NA

DBSCAN-SWA_10

1979591 : 2027337

Staphylococcus_phage(66.18%)

protease,transposase,holin,integrase,tail,terminase,portal,head,capsid

attL 1993093:1993107|attR 2028894:2028908

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ28070.1\|1979591_1980320_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0
VDZ28072.1\|1980343_1981132_+	insertion element protein	A0A0C5AEA5	Paenibacillus_phage	5.7e-49	51.4
VDZ28074.1\|1981300_1981816_-	ThiJ/PfpI family protein	NA	NA	NA	NA
VDZ28076.1\|1981945_1982107_-	Putative cytosolic protein	NA	NA	NA	NA
VDZ28078.1\|1982579_1983581_-	BcgI-like restriction enzyme subunit beta	A0A1W6JNN3	Staphylococcus_phage	1.0e-55	40.1
VDZ28080.1\|1983564_1985457_-	BcgI-like restriction enzyme subunit alpha	A0A1W6JNK1	Staphylococcus_phage	5.6e-268	70.9
VDZ28082.1\|1985968_1986937_-	Panton-Valentine leukocidin LukF-PV chain precursor	Q9MBN2	Staphylococcus_prophage	2.0e-181	100.0
VDZ28084.1\|1986938_1987865_-	leukocidin chain lukM precursor	Q9MBN3	Staphylococcus_prophage	4.2e-176	99.7
VDZ28086.1\|1988212_1988968_-	Autolysin	Q9MBN4	Staphylococcus_prophage	3.4e-152	100.0
VDZ28088.1\|1988979_1989234_-\|holin	Phage holin	Q9MBN5	Staphylococcus_prophage	5.3e-41	100.0
VDZ28090.1\|1990127_1990415_-	phage protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
VDZ28092.1\|1990461_1990614_-	phage protein	D2JLG0	Staphylococcus_phage	1.2e-19	98.0
VDZ28094.1\|1990603_1994389_-	phage minor structural protein	D2JLF9	Staphylococcus_phage	0.0e+00	97.3
1993093:1993107	attL	NA	NA	NA	NA
VDZ28096.1\|1994404_1995895_-\|tail	phage tail family protein	D2JLF8	Staphylococcus_phage	1.4e-295	99.0
VDZ28098.1\|1995894_2000544_-\|tail	phage tail tape measure protein, TP901 family, core region	A0A1V0E5H1	Staphylococcus_phage	0.0e+00	97.7
VDZ28100.1\|2000781_2001228_-	Bacteriophage	D2JLF5	Staphylococcus_phage	1.2e-72	99.3
VDZ28102.1\|2001292_2002246_-\|tail	phage major tail, phi13 family protein	A7TWD0	Staphylococcus_phage	2.5e-168	95.6
VDZ28104.1\|2002246_2002627_-	phi PVL orf 12-like protein	D2JLF3	Staphylococcus_phage	5.8e-68	100.0
VDZ28106.1\|2002623_2003001_-	gp10 family phage protein	D2JLF2	Staphylococcus_phage	4.0e-61	99.2
VDZ28108.1\|2003000_2003336_-\|head,tail	phage head-tail adaptor	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
VDZ28110.1\|2003322_2003655_-\|head,tail	phage gp6-like head-tail connector family protein	D2JLF0	Staphylococcus_phage	6.2e-58	99.1
VDZ28112.1\|2003663_2003822_-	Bacteriophage	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
VDZ28114.1\|2003857_2005105_-\|capsid	phage major capsid protein, HK97 family	Q8SDK8	Staphylococcus_phage	1.1e-208	97.3
VDZ28116.1\|2005192_2005777_-\|head,protease	prohead protease	D2JLE7	Staphylococcus_phage	2.9e-106	99.5
VDZ28118.1\|2005769_2007020_-\|portal	portal protein	D2JLE6	Staphylococcus_phage	9.7e-237	99.8
VDZ28120.1\|2007025_2007265_-	phi PVL orf 3-like protein	A7TWC1	Staphylococcus_phage	3.5e-34	97.5
VDZ28122.1\|2007239_2008934_-	phage Terminase family protein	D2JLE4	Staphylococcus_phage	0.0e+00	99.3
VDZ28124.1\|2008936_2009404_-\|terminase	phage terminase small subunit	D2JLE3	Staphylococcus_phage	1.6e-80	98.7
VDZ28126.1\|2009533_2009887_-	phage endonuclease	D2JLE2	Staphylococcus_phage	1.3e-66	100.0
VDZ28128.1\|2009893_2010346_-	hypothetical phage-related protein	D2JLE1	Staphylococcus_phage	1.4e-79	100.0
VDZ28130.1\|2010460_2010922_-	Phage protein	D2JLE0	Staphylococcus_phage	3.6e-72	100.0
VDZ28132.1\|2010944_2011145_-	phage protein	D2JLD9	Staphylococcus_phage	2.4e-28	98.5
VDZ28134.1\|2011144_2011795_-	Uncharacterised protein	D2JLD8	Staphylococcus_phage	3.8e-115	98.1
VDZ28136.1\|2011953_2012103_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	1.4e-17	98.0
VDZ28138.1\|2012099_2012306_-	Protein of uncharacterised function (DUF1381)	B7T0C2	Staphylococcus_virus	6.0e-19	95.6
VDZ28140.1\|2012342_2012684_-	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	4.8e-53	100.0
VDZ28142.1\|2012676_2012925_-	Phage protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
VDZ28144.1\|2012917_2013193_-	Phage protein	Q4ZA41	Staphylococcus_virus	1.3e-45	100.0
VDZ28146.1\|2013192_2013603_-	putative phage PVL protein	A0A1P8CN10	Staphylococcus_phage	6.1e-47	68.4
VDZ28148.1\|2013605_2013815_-	Phage protein	A0A059T5A6	Staphylococcus_phage	5.9e-30	88.2
VDZ28150.1\|2013825_2014074_-	phage family protein	A0A2I6PDI0	Staphylococcus_phage	4.0e-41	95.1
VDZ28152.1\|2014074_2014446_-	PVL ORF-50-like family protein	Q9MBR4	Staphylococcus_prophage	1.4e-50	96.7
VDZ28154.1\|2014457_2014715_-	helix-turn-helix DNA binding protein	Q9MBR5	Staphylococcus_prophage	5.4e-41	100.0
VDZ28156.1\|2014715_2014901_-	PV83 orf 23-like protein	Q9MBR6	Staphylococcus_prophage	1.7e-25	96.7
VDZ28158.1\|2014905_2015310_-	hypothetical phage-related protein	A7TWN5	Staphylococcus_phage	3.3e-69	96.3
VDZ28160.1\|2015320_2015542_-	putative phi ETA-like protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
VDZ28162.1\|2015544_2015760_-	hypothetical phage-related protein	Q4ZA49	Staphylococcus_virus	6.3e-35	100.0
VDZ28164.1\|2015813_2016998_-	prophage L54a, replicative DNA helicase	Q4ZA50	Staphylococcus_virus	8.4e-214	98.2
VDZ28166.1\|2016994_2017351_-	phage protein	M9NS37	Staphylococcus_phage	8.2e-64	100.0
VDZ28168.1\|2017350_2018106_-	hypothetical phage-related protein	B7T0A7	Staphylococcus_virus	1.7e-143	100.0
VDZ28170.1\|2018098_2018773_-	phage protein	Q4ZA53	Staphylococcus_virus	2.0e-127	98.2
VDZ28172.1\|2018786_2019215_-	Single-stranded DNA-binding protein, phage associated	D2JGK2	Staphylococcus_phage	1.1e-59	92.3
VDZ28174.1\|2019214_2019853_-	putative phage single-strand DNA binding protein	Q9MBS2	Staphylococcus_prophage	1.7e-115	100.0
VDZ28176.1\|2019852_2020332_-	phage protein	Q9MBS3	Staphylococcus_prophage	8.1e-83	100.0
VDZ28178.1\|2020346_2020607_-	phage protein	Q9MBS4	Staphylococcus_prophage	1.5e-43	100.0
VDZ28180.1\|2020701_2020863_-	phage protein	A9CR58	Staphylococcus_phage	3.3e-20	96.2
VDZ28182.1\|2020846_2021077_-	phage protein	Q9MBS7	Staphylococcus_prophage	1.5e-31	100.0
VDZ28184.1\|2021147_2021360_+	Uncharacterised protein	A0A2H4JBA9	uncultured_Caudovirales_phage	3.2e-15	56.5
VDZ28186.1\|2021287_2021452_-	phi PV83 orf 10-like protein	A0A2H4J3T9	uncultured_Caudovirales_phage	9.4e-07	61.1
VDZ28188.1\|2021467_2022217_-	putative phage anti-repressor protein	A0A1W6JPN2	Staphylococcus_phage	7.6e-136	99.6
VDZ28190.1\|2022277_2022520_+	Uncharacterised protein	Q4ZCA7	Staphylococcus_virus	2.8e-15	50.0
VDZ28192.1\|2022467_2022755_-	Uncharacterised protein	NA	NA	NA	NA
VDZ28194.1\|2022809_2023019_+	Uncharacterised protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
VDZ28196.1\|2023011_2023152_-	phage protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
VDZ28198.1\|2023166_2023610_-	hypothetical phage-related protein	W5R971	Staphylococcus_phage	4.1e-73	98.6
VDZ28200.1\|2023657_2023870_-	helix-turn-helix family protein	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
VDZ28202.1\|2024021_2024753_+	CI-like repressor, phage associated	M9NUL0	Staphylococcus_phage	5.6e-91	72.2
VDZ28204.1\|2024764_2024911_+	phage protein	U5U441	Staphylococcus_phage	4.3e-19	100.0
VDZ28206.1\|2024907_2025093_+	phage protein	A0A1X9H0K5	Staphylococcus_phage	2.5e-24	98.4
VDZ28208.1\|2025128_2026112_+	Protein of uncharacterised function (DUF3644)	A0A0N9RUA4	Staphylococcus_phage	9.9e-168	92.0
VDZ28210.1\|2026290_2027337_+\|integrase	phage integrase family protein	Q4ZDS8	Staphylococcus_virus	1.8e-199	98.9
2028894:2028908	attR	NA	NA	NA	NA

DBSCAN-SWA_11

2109396 : 2120903

Staphylococcus_phage(45.45%)

integrase

attL 2101221:2101244|attR 2124078:2124101

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2101221:2101244	attL	NA	NA	NA	NA
VDZ28308.1\|2109396_2109888_-	pathogenicity island protein	A0A2H4JB26	uncultured_Caudovirales_phage	3.0e-24	39.9
VDZ28309.1\|2110053_2111112_-	pahtogenicity island protein	NA	NA	NA	NA
VDZ28310.1\|2111098_2111305_-	pathogenicity island protein	NA	NA	NA	NA
VDZ28311.1\|2111529_2111874_-	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	1.2e-40	64.3
VDZ28312.1\|2112544_2114917_-	Putative DNA primase	A0A2H4JCU9	uncultured_Caudovirales_phage	6.7e-146	41.3
VDZ28313.1\|2115008_2115308_-	bovine pathogenicity island protein Orf16	Q4ZE75	Staphylococcus_phage	5.9e-31	66.7
VDZ28314.1\|2115308_2115533_-	pathogenicity island protein	A0A1W6JPA6	Staphylococcus_phage	3.4e-15	60.3
VDZ28315.1\|2115522_2115672_-	hypothetical bovine pathogenicity island protein	NA	NA	NA	NA
VDZ28316.1\|2115668_2115986_-	mobile element-associated transcriptional regulator, putative	A0A1W6JQE0	Staphylococcus_phage	1.7e-49	96.2
VDZ28317.1\|2115999_2116641_-	putative prophage antirepressor	A0A2H4JB17	uncultured_Caudovirales_phage	2.3e-96	82.2
VDZ28318.1\|2116644_2116857_-	putative transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	7.9e-06	45.5
VDZ28319.1\|2117010_2117673_+	putative transcriptional regulator	NA	NA	NA	NA
VDZ28320.1\|2117685_2118858_+\|integrase	mobile element-associated integrase, putative	A0A1W6JQD3	Staphylococcus_phage	3.5e-220	98.5
VDZ28321.1\|2118926_2120543_-	heat shock protein 60 family chaperone GroEL	A0A240F779	uncultured_virus	1.2e-157	54.9
VDZ28322.1\|2120618_2120903_-	Heat shock protein 60 family co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
2124078:2124101	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2553634 : 2601927

Bacillus_phage(36.36%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VDZ28723.1\|2553634_2554330_-\|holin	putative glycine betaine/carnitine/choline transport system permease protein	NA	NA	NA	NA
VDZ28724.1\|2554329_2555271_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, substrate-binding protein OpuCC	NA	NA	NA	NA
VDZ28725.1\|2555287_2555923_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCB	NA	NA	NA	NA
VDZ28726.1\|2555919_2557146_-\|holin	glycine betaine/carnitine/choline ABC transporter, ATP-binding protein, putative	Q6GZ03	Mycoplasma_phage	6.6e-20	50.5
VDZ28727.1\|2557815_2558415_-	molecular chaperone GroEL	NA	NA	NA	NA
VDZ28728.1\|2558594_2560232_+	Amino acid permease	NA	NA	NA	NA
VDZ28729.1\|2560538_2561891_+	Carboxylesterase type B	A0A0B5J865	Pandoravirus	2.5e-12	34.2
VDZ28730.1\|2561952_2563140_-	chloramphenicol resistance protein	NA	NA	NA	NA
VDZ28731.1\|2563534_2564311_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
VDZ28732.1\|2564303_2564966_-	ABC superfamily ATP binding cassette transporter, ABC protein	W8CYL7	Bacillus_phage	1.7e-17	34.5
VDZ28733.1\|2565310_2566387_-	endoglucanase M	NA	NA	NA	NA
VDZ28734.1\|2566742_2567009_-	addiction module toxin	NA	NA	NA	NA
VDZ28735.1\|2567008_2567266_-	prevent-host-death family protein	NA	NA	NA	NA
VDZ28736.1\|2567626_2568082_+	lipoprotein	NA	NA	NA	NA
VDZ28737.1\|2568249_2569827_-	Ferredoxin-dependent glutamate synthase	NA	NA	NA	NA
VDZ28738.1\|2570020_2570770_+	membrane protein	NA	NA	NA	NA
VDZ28739.1\|2570993_2572187_-	Antibiotic resistance protein	NA	NA	NA	NA
VDZ28740.1\|2572198_2572948_-	nickel transport ATP-binding protein	G3M9Y6	Bacillus_virus	8.1e-21	31.2
VDZ28741.1\|2572940_2573756_-	Oligopeptide transporter putative ATPase domain protein	G9BWD6	Planktothrix_phage	3.6e-14	29.8
VDZ28742.1\|2573752_2574622_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
VDZ28743.1\|2574618_2575554_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
VDZ28744.1\|2575566_2577165_-	Oligopeptide transporter putative substrate binding domain protein	NA	NA	NA	NA
VDZ28745.1\|2577307_2578609_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VDZ28746.1\|2578601_2579420_-	nicotianamine synthase	NA	NA	NA	NA
VDZ28747.1\|2579430_2580252_-	Putative Similar to diaminopimelate epimerase	NA	NA	NA	NA
VDZ28748.1\|2581192_2581555_-	Uncharacterised protein	NA	NA	NA	NA
VDZ28749.1\|2581818_2582637_-	short chain dehydrogenase	L7RG25	Acanthamoeba_polyphaga_moumouvirus	4.4e-12	26.8
VDZ28750.1\|2582872_2584411_+	aminobenzoyl-glutamate transport protein	NA	NA	NA	NA
VDZ28751.1\|2584522_2584945_-\|transposase	transposase	NA	NA	NA	NA
VDZ28752.1\|2585400_2585820_-	membrane protein	NA	NA	NA	NA
VDZ28753.1\|2586070_2586766_-	Short-chain alcohol dehydrogenase	W8CYX9	Bacillus_phage	8.6e-09	36.5
VDZ28754.1\|2587065_2587347_+	IraB protein	NA	NA	NA	NA
VDZ28755.1\|2587606_2587798_-	Uncharacterised protein	NA	NA	NA	NA
VDZ28756.1\|2588151_2588445_-	Uncharacterised protein	NA	NA	NA	NA
VDZ28757.1\|2588447_2588774_-	Putative cytosolic protein	NA	NA	NA	NA
VDZ28758.1\|2588773_2590129_-	Insertion sequenceATP-binding protein, putative	NA	NA	NA	NA
VDZ28759.1\|2590128_2590911_-	putative lipoprotein	NA	NA	NA	NA
VDZ28760.1\|2591154_2591931_-	lipoprotein	NA	NA	NA	NA
VDZ28761.1\|2592234_2595096_-	DNA/RNA helicase of DEAD/DEAH box family	Q5YA94	Bacillus_phage	2.4e-28	27.9
VDZ28762.1\|2595097_2595490_-	7,8-dihydro-8-oxoguanine-triphosphatase	NA	NA	NA	NA
VDZ28763.1\|2595792_2597430_+	Phosphoglucomutase	A0A1X9I671	Streptococcus_phage	6.4e-95	37.7
VDZ28764.1\|2597713_2597980_+	exported protein	NA	NA	NA	NA
VDZ28765.1\|2598123_2598432_+	membrane protein	NA	NA	NA	NA
VDZ28766.1\|2598538_2598709_-	Uncharacterised protein	NA	NA	NA	NA
VDZ28767.1\|2598752_2599946_-	Macrolide-efflux protein	NA	NA	NA	NA
VDZ28768.1\|2600122_2600989_-	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	3.4e-79	52.9
VDZ28769.1\|2601198_2601927_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0

Anti-CRISPR protein detection

Acr_ID: LR134090.1|VDZ28142.1|2012676_2012925_-|Phage-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LR134090.1|VDZ28142.1|2012676_2012925_-|Phage-protein

2012676_2012925_-

82 aa aa

1979591-2027337

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
LR134090_8	Orphan	8.2\|2366244\|18\|LR134090\|CRT	2366244-2366261	18	2000892-2000909	2

1. spacer 8.2|2366244|18|LR134090|CRT matches to LR134090 position: 2000892-2000909, mismatch: 2

ctttttgaaattctctat	CRISPR spacer
ctttttgaagttctatat	Protospacer
*********.**** ***

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134090

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information