CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134193	Staphylococcus aureus strain NCTC13616 genome assembly, chromosome: 1	6 crisprs	cas3,DEDDh,RT,DinG,csa3,WYL	5	0	15	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134193_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134193_1

285126-285263

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGGGCCCCAACATAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of LR134193_1

>merge|LR134193|1|285126-285263|CRISPRCasFinder
TGCAAGTTGGCGGGGCCCCAACATAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGGGAGGGACATAAATAAA

>LR134193|1|1|285126-285263|CRISPRCasFinder
TGCAAGTTGGCGGGGCCCCAACATAGA	GAATTTCGAAAAGAAATTCTACAGGCAA
TGCAAGTTGGCGGGGCCCCAACATAGA	AGCTGGCGGAAAGTCAGCTTACAATAATG
TGCAAGTTGGGGAGGGACATAAATAAA

Protein	Signature genes	Signature genes Name	Protein_function
LR134193.1\|VEB63823.1\|277059_277800_+\|Autolysis-response-regulater-LytR	unknown	unknown	gnl\|CDD\|184495
LR134193.1\|VEB63845.1\|287871_288753_-\|sugar-transport-protein	unknown	unknown	gnl\|CDD\|284268
LR134193.1\|VEB63815.1\|272517_274239_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|376098
LR134193.1\|VEB63849.1\|290363_290756_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134193.1\|VEB63818.1\|274382_275057_+\|DnrN	unknown	unknown	gnl\|CDD\|183940
LR134193.1\|VEB63840.1\|286510_287425_-\|Ribokinase	unknown	unknown	gnl\|CDD\|274000
LR134193.1\|VEB63835.1\|283567_285004_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
LR134193.1\|VEB63855.1\|293811_294759_+\|peptidoglycan-hydrolase	unknown	unknown	gnl\|CDD\|226451
LR134193.1\|VEB63829.1\|279390_281682_+\|nitric-oxide-reductase	unknown	unknown	gnl\|CDD\|225795
LR134193.1\|VEB63820.1\|275302_277057_+\|Autolysis-histidine-kinase-LytS	unknown	unknown	gnl\|CDD\|225814
LR134193.1\|VEB63857.1\|294810_295470_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
LR134193.1\|VEB63851.1\|290883_292260_-\|multidrug-resistance-protein-B	unknown	unknown	gnl\|CDD\|129794
LR134193.1\|VEB63838.1\|285498_286260_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
LR134193.1\|VEB63853.1\|292493_293486_+\|choloylglycine-hydrolase	unknown	unknown	gnl\|CDD\|225591
LR134193.1\|VEB63831.1\|281907_282612_-\|Transcriptional-regulator,-GntR-family	unknown	unknown	gnl\|CDD\|225099
LR134193.1\|VEB63833.1\|282760_283552_+\|PTS-system,-N-acetylglucosamine-specific-IIA-component-/-PTS-system,-N-acetylglucosamine-specific-IIB-component-/-PTS-system,-N-acetylglucosamine-specific-IIC-component	unknown	unknown	gnl\|CDD\|225101
LR134193.1\|VEB63827.1\|278348_279050_+\|LrgA-associated-membrane-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
LR134193.1\|VEB63847.1\|288984_289983_-\|ribose-operon-repressor,-putative	unknown	unknown	gnl\|CDD\|224525
LR134193.1\|VEB63825.1\|277918_278356_+\|holin-like-protein	unknown	unknown	gnl\|CDD\|235222
LR134193.1\|VEB63843.1\|287452_287857_-\|Ribose-ABC-transport-system,-high-affinity-permease-RbsD	unknown	unknown	gnl\|CDD\|183318

Protein	Function_ID	Function_description	E-value
LR134193.1\|VEB63823.1\|277059_277800_+\|Autolysis-response-regulater-LytR	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
LR134193.1\|VEB63845.1\|287871_288753_-\|sugar-transport-protein	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117
LR134193.1\|VEB63815.1\|272517_274239_+\|glycosyl-transferase	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	3.18504e-35
LR134193.1\|VEB63818.1\|274382_275057_+\|DnrN	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	1.30038e-153
LR134193.1\|VEB63840.1\|286510_287425_-\|Ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	7.32816e-143
LR134193.1\|VEB63835.1\|283567_285004_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
LR134193.1\|VEB63855.1\|293811_294759_+\|peptidoglycan-hydrolase	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.47013e-32
LR134193.1\|VEB63829.1\|279390_281682_+\|nitric-oxide-reductase	gnl\|CDD\|225795	COG3256, NorB, Nitric oxide reductase large subunit [Inorganic ion transport and metabolism].	5.48419e-178
LR134193.1\|VEB63820.1\|275302_277057_+\|Autolysis-histidine-kinase-LytS	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
LR134193.1\|VEB63857.1\|294810_295470_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.68709e-67
LR134193.1\|VEB63851.1\|290883_292260_-\|multidrug-resistance-protein-B	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.58117e-30
LR134193.1\|VEB63838.1\|285498_286260_-\|SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.23141e-27
LR134193.1\|VEB63853.1\|292493_293486_+\|choloylglycine-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	6.16271e-152
LR134193.1\|VEB63831.1\|281907_282612_-\|Transcriptional-regulator,-GntR-family	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.13754e-62
LR134193.1\|VEB63833.1\|282760_283552_+\|PTS-system,-N-acetylglucosamine-specific-IIA-component-/-PTS-system,-N-acetylglucosamine-specific-IIB-component-/-PTS-system,-N-acetylglucosamine-specific-IIC-component	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	8.99936e-55
LR134193.1\|VEB63827.1\|278348_279050_+\|LrgA-associated-membrane-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
LR134193.1\|VEB63847.1\|288984_289983_-\|ribose-operon-repressor,-putative	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.32136e-100
LR134193.1\|VEB63825.1\|277918_278356_+\|holin-like-protein	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	2.74631e-64
LR134193.1\|VEB63843.1\|287452_287857_-\|Ribose-ABC-transport-system,-high-affinity-permease-RbsD	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	4.08879e-70

>LR134193.1|VEB63835.1|283567_285004_+|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKVHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYKQVIASNGDKL
>LR134193.1|VEB63833.1|282760_283552_+|PTS-system,-N-acetylglucosamine-specific-IIA-component-/-PTS-system,-N-acetylglucosamine-specific-IIB-component-/-PTS-system,-N-acetylglucosamine-specific-IIC-component
MSNKYKDQAQDILTAVGGVENIVDVTYDTKGITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKDANVEEGANTDNINSQDTSYTPQAKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAIGIRSEEGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>LR134193.1|VEB63831.1|281907_282612_-|Transcriptional-regulator,-GntR-family
MLKYEHIAKQLNAFIHHSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEIATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDQLNSSEAALLQLSKGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>LR134193.1|VEB63829.1|279390_281682_+|nitric-oxide-reductase
MSMQSSYKRLVKVLLTILVIVFSILLVGGWYIFKNEAPRPTKIVDQQGHTLVTKGELISGQAIYEKYGLTDYGSYLGNGSYLGPDYTAEALHHYLIGMRKYYAQDIYHKQLHKLNHAELAVVKDKVMKEIRINRYSEKEDQLVLTPGQVYGLKYLQDYYKKEFVNNPKQVGLNENMIKQFQNDDYMVAGNKVEHLSQFFFWGAWLSSTDRPGKTFSYTNNWPYDVDAGNTLPSAGILWTAISVTLLIAGLAFIIYIQKRYQFDMKPTYESERELPKIEVDRKITDSQRKVGKYLVVVMLLFLVQILLGELLAHYYVENKFFGIEIQRLFPFNIAKTWHVQLVIFWVATTWLAAGIYIVPKVLGKEPKKQGVLVDILFWALIIVVMGSMIGEWGHILGWIDSHWWLFGHFGWEYIELGKFWQILFIVGMVLWVIILCRGFLPAIRNKVQVNHDKRHLLTLLFVGAIAIPLFYLASLFIMPNSHVTFADYWRWWIVHLWVEGIFEAFAVVLIGFLMVNMKLTTIETTIRALYFQLILLLGTGIVGMGHHYYWQGDHSIWLALGSCFSALEVVPLCLLIWEAYTHYRLYKNSDIAFPYKGTFIFLASTGLWNAIGAGALGFLINTPAVNYFEHGTQWTAAHAHGSMAGVYGMFSIAIALYVFKNITKKEFWTPKVEKWIKISCWALNIGLAGMVFVTLMPVGYIQLKDALEHGYWHSRLTSFYEQPLVKAIMWGRMPWDIIFTVGVIILVVIFIRGYRHLKPKYRV
>LR134193.1|VEB63827.1|278348_279050_+|LrgA-associated-membrane-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>LR134193.1|VEB63825.1|277918_278356_+|holin-like-protein
MKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>LR134193.1|VEB63823.1|277059_277800_+|Autolysis-response-regulater-LytR
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>LR134193.1|VEB63820.1|275302_277057_+|Autolysis-histidine-kinase-LytS
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>LR134193.1|VEB63818.1|274382_275057_+|DnrN
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAAVLEKKNVDLNELLQRLNEVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKATYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>LR134193.1|VEB63815.1|272517_274239_+|glycosyl-transferase
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLTVNANKQYRFNIMLEDIKADLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMVMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>LR134193.1|VEB63838.1|285498_286260_-|SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYHQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTLKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKEH
>LR134193.1|VEB63840.1|286510_287425_-|Ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKSHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>LR134193.1|VEB63843.1|287452_287857_-|Ribose-ABC-transport-system,-high-affinity-permease-RbsD
MKKTAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>LR134193.1|VEB63845.1|287871_288753_-|sugar-transport-protein
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>LR134193.1|VEB63847.1|288984_289983_-|ribose-operon-repressor,-putative
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMIVVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>LR134193.1|VEB63849.1|290363_290756_+|Uncharacterised-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKENYNKYIQGQKQRVIFENGHFV
>LR134193.1|VEB63851.1|290883_292260_-|multidrug-resistance-protein-B
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>LR134193.1|VEB63853.1|292493_293486_+|choloylglycine-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGQSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATANLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>LR134193.1|VEB63855.1|293811_294759_+|peptidoglycan-hydrolase
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSAQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATTGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPMSYLQSR
>LR134193.1|VEB63857.1|294810_295470_-|ABC-transporter-ATP-binding-protein
MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLLRMIAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENIKFFKSLCKNPINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGKPRILILDEPTVGIDLKSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWTYTYY

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Crispr_ID: LR134193_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134193_2

625111-625198

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAGGCAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134193_2

>merge|LR134193|2|625111-625198|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGGCAATGTAAGTTGG

>LR134193|2|2|625111-625198|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGG	GGTGTGGGCCCCAACACAGAGAATTTCA
AAAAGAAATTCTACAGGCAATGTAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134193.1\|VEB64351.1\|625456_625993_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-ywqN	unknown	unknown	gnl\|CDD\|223728
LR134193.1\|VEB64350.1\|624020_624959_+\|Oxidoreductase-ion-channel	unknown	unknown	gnl\|CDD\|381309
LR134193.1\|VEB64346.1\|620103_621498_+\|Phage-protein	unknown	unknown	gnl\|CDD\|368093
LR134193.1\|VEB64345.1\|619039_619480_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|224870
LR134193.1\|VEB64348.1\|622180_622801_+\|membrane-spanning-protein	unknown	unknown	gnl\|CDD\|335700
LR134193.1\|VEB64344.1\|617730_619053_-\|putative-dehydrogenase,-Mercuric-ion-reductase-like-protein	unknown	unknown	gnl\|CDD\|180907
LR134193.1\|VEB64349.1\|622940_623573_+\|Putative-membrane-spanning-protein	unknown	unknown	gnl\|CDD\|335700
LR134193.1\|VEB64359.1\|632715_633351_+\|endonuclease-III-domain-protein	unknown	unknown	gnl\|CDD\|225140
LR134193.1\|VEB64354.1\|628015_628522_+\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|378039
LR134193.1\|VEB64342.1\|616084_617161_+\|Phosphomevalonate-kinase	unknown	unknown	gnl\|CDD\|130287
LR134193.1\|VEB64353.1\|626677_627973_+\|Deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl\|CDD\|224004
LR134193.1\|VEB64343.1\|617337_617679_+\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|377806
LR134193.1\|VEB64355.1\|629020_630031_+\|Alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
LR134193.1\|VEB64360.1\|633723_634611_+\|Periplasmic-binding-protein	unknown	unknown	gnl\|CDD\|238563
LR134193.1\|VEB64347.1\|621501_622134_+\|Putative-membrane-spanning-protein	unknown	unknown	gnl\|CDD\|335700
LR134193.1\|VEB64341.1\|615088_616072_+\|Diphosphomevalonate-decarboxylase	unknown	unknown	gnl\|CDD\|225941
LR134193.1\|VEB64358.1\|630720_632382_+\|Arginyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234964
LR134193.1\|VEB64352.1\|626161_626638_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|366181
LR134193.1\|VEB64356.1\|630107_630215_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134193.1\|VEB64357.1\|630307_630724_+\|Uncharacterized-beta-barrel-protein-ywiB	unknown	unknown	gnl\|CDD\|226896

Protein	Function_ID	Function_description	E-value
LR134193.1\|VEB64351.1\|625456_625993_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-ywqN	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
LR134193.1\|VEB64350.1\|624020_624959_+\|Oxidoreductase-ion-channel	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	1.11883e-166
LR134193.1\|VEB64346.1\|620103_621498_+\|Phage-protein	gnl\|CDD\|368093	pfam04740, LXG, LXG domain of WXG superfamily. This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.	1.09874e-10
LR134193.1\|VEB64345.1\|619039_619480_-\|DNA-binding-protein	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	2.0619e-25
LR134193.1\|VEB64348.1\|622180_622801_+\|membrane-spanning-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	3.87e-58
LR134193.1\|VEB64344.1\|617730_619053_-\|putative-dehydrogenase,-Mercuric-ion-reductase-like-protein	gnl\|CDD\|180907	PRK07251, PRK07251, FAD-containing oxidoreductase.	0
LR134193.1\|VEB64349.1\|622940_623573_+\|Putative-membrane-spanning-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.26478e-44
LR134193.1\|VEB64359.1\|632715_633351_+\|endonuclease-III-domain-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.15274e-92
LR134193.1\|VEB64354.1\|628015_628522_+\|Putative-cytosolic-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	1.08203e-97
LR134193.1\|VEB64342.1\|616084_617161_+\|Phosphomevalonate-kinase	gnl\|CDD\|130287	TIGR01220, phosphomevalonate_kinase, phosphomevalonate kinase, ERG8-type, Gram-positive branch. This enzyme is part of the mevalonate pathway, one of two alternative pathways for the biosynthesis of IPP. In an example of nonorthologous gene displacement, two different types of phosphomevalonate kinase are found - the animal type and this ERG8 type. This model represents the low GC Gram-positive organism forms of the ERG8 type of phosphomevalonate kinase. [Central intermediary metabolism, Other].	0
LR134193.1\|VEB64353.1\|626677_627973_+\|Deoxyguanosinetriphosphate-triphosphohydrolase	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
LR134193.1\|VEB64343.1\|617337_617679_+\|Putative-cytosolic-protein	gnl\|CDD\|377806	pfam07293, DUF1450, Protein of unknown function (DUF1450). This family consists of several hypothetical bacterial proteins of around 80 residues in length. Members of this family contain four highly conserved cysteine residues. The function of this family is unknown.	8.95773e-05
LR134193.1\|VEB64355.1\|629020_630031_+\|Alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
LR134193.1\|VEB64360.1\|633723_634611_+\|Periplasmic-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	4.84401e-73
LR134193.1\|VEB64347.1\|621501_622134_+\|Putative-membrane-spanning-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	5.71299e-61
LR134193.1\|VEB64341.1\|615088_616072_+\|Diphosphomevalonate-decarboxylase	gnl\|CDD\|225941	COG3407, MVD1, Mevalonate pyrophosphate decarboxylase [Lipid metabolism].	3.00487e-147
LR134193.1\|VEB64358.1\|630720_632382_+\|Arginyl-tRNA-synthetase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
LR134193.1\|VEB64352.1\|626161_626638_+\|acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
LR134193.1\|VEB64357.1\|630307_630724_+\|Uncharacterized-beta-barrel-protein-ywiB	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58

>LR134193.1|VEB64350.1|624020_624959_+|Oxidoreductase-ion-channel
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKLAEQVVENIKAADIVLSDDEIQYIDELFPIED
>LR134193.1|VEB64349.1|622940_623573_+|Putative-membrane-spanning-protein
MLCEVIAIYKNPKYRIIKYNDEYLMVNIINNWLVLFIPLLNWLTPKRYIKISQEELESLNTFKPAKNNAFWPALGSSVLFSVTFRKYMPLFNVRLEKTIVIAIFFVVFLGILFFYLNLNRRLALSVFTMNKEKSQKMILLPNLKHFFFIIFAYLYFGGFSFFTLYALITIDVQNIIIFICWGAVTMFFFFINIVPIGIKKAHVILLKKAE
>LR134193.1|VEB64348.1|622180_622801_+|membrane-spanning-protein
MLCESKIINKNPKYRIIKYNDEYLMIDIISTWISLFFPFINWFITKRYVKISREEFENLNIVKPAKKNVFWPVAGSSALLGVALRKYTHLLDVQLDKKLVIAICCITFIGILIFYVRLIKKSSLNIYNTKNKRSKIFLIPTLKNVCFTLFGYILFGGLTMLFLDALLSMSYQNIIVYFAWITAIMGFFLVNIALIIDKNIHVILKN
>LR134193.1|VEB64347.1|621501_622134_+|Putative-membrane-spanning-protein
MLCESKVINKNPKYRIIKYESEYLMIDLASNWIVFFFPFINWLIPKTYVKITKNDYEKLNIVKPVKNKSIGWTIFAGIVLLGGTVRRNTYLFDFQLEKLIVWSSCFISFLGVIFFYCYLNKKLTLNVYKENKNNELKLRLLPSFKNMCFTIFYYLFTGFMSYGAFYLLVFENVQNLILYISWLFMTMLFMLMNMHSIIDKKVHIFLKSNK
>LR134193.1|VEB64346.1|620103_621498_+|Phage-protein
MSIDMYLDRSRNQASSVGNLSQTMNSNYDALEKAITQFINDDALKGKAYTSAKQFFSTVLIPLSTSMKTLSDLTKQACDNFVSRYTSEVDSISLKESELEEDIRSLSQQITRYENLTNNLKKHASDNQQAISSNQQIIQTLGQQKHELEEKLRKLREFNQKSPEIFKEVEEFQKIVQQGLTQAQNFWNFSTNQFNIPSGKELDWAKASHEKYLKVAMGKIEHKAEKETLNKADFAVIKAYAKEHPEDDIPKSIMKYINDNKDSIKRDIGLDITSTLLEQGGINASKFGVFINTAGGVKGPAGPNSFVEVKRTSGNVFIENGSKFAKGGKYLGKGVAGVGFGIGMYDDLANDDKTFGEALSHNGMTLAAGSVAAFGVAALVSNPVGWAVVGILTAGIIGSIVSDYLYQNNYFGIKDKVDWAGHKIDEGIDAVNKTAEKAVDSVGNTIGDATKSISNHINPMKWSW
>LR134193.1|VEB64345.1|619039_619480_-|DNA-binding-protein
MNLEFNIAVHVLAFLTKHHSEKFNSSSLAELTCLNPVQLRRVTTQLVDLKMINTIRGKDGGYLANDQSADVSLATLYKHFVLEKKHHTRLFTGDEGSHCQIARNIATTMSHYQQDEQNIIINFYNGKTIKDVIEDIQKEDLCHENI
>LR134193.1|VEB64344.1|617730_619053_-|putative-dehydrogenase,-Mercuric-ion-reductase-like-protein
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIADSITAPHIIINTGATSVIPNIKDLDQAKHVFDSTGLLNINYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF
>LR134193.1|VEB64343.1|617337_617679_+|Putative-cytosolic-protein
MKNTFLICDECQAVNIRTLQKKLEKLDPDAEIVIGCQSYCGPGRRKTFTFVNNRPLAALTEEELIEKVSQQLKKPRDSEEEERLRKRHEERKRRKEEQDRKLKEKLEKRKAQQ
>LR134193.1|VEB64342.1|616084_617161_+|Phosphomevalonate-kinase
MIQVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEEADQYKGTIHSKALHHNPVTFSRDEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHFHLTIDSNLDDSNGHKYGLGSSAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAYSTFDHEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHFVSEVKRLKSDPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKMVRQNRTIIQRMDKEATVDIETEKLKYLCDIAEKYHGASKTSGAGGGDCGITIINKDVDKEKIYDEWTKHGIKPLKFNIYHGQ
>LR134193.1|VEB64341.1|615088_616072_+|Diphosphomevalonate-decarboxylase
MIKSGKARAHTNIALIKYWGKKDEALIIPMNNSISVTLEKFYTETKVTFNDQLTQDQFWLNGEKVSGKELEKISKYMDIVRNRAGIDWYAEIESDNFVPTAAGLASSASAYAALAAACNQALDMQLSDKDLSRLARIGSGSASRSIYGGFAEWEKGYSDETSYAVPLESNHFEDDLAMIFVVINQHSKKVPSRYGMSLTRNTSRFYQYWLDHIDEDLAEAKAAIQDKDFKRLGEVIEENGLRMHATNLGSTPPFTYLVQESYDVMALVHECREAGYPCYFTMDAGPNVKILVEKKNKQQIIDKLLTQFDNNQIIDSDIIATGIEIIE
>LR134193.1|VEB64351.1|625456_625993_+|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-ywqN
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>LR134193.1|VEB64352.1|626161_626638_+|acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>LR134193.1|VEB64353.1|626677_627973_+|Deoxyguanosinetriphosphate-triphosphohydrolase
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>LR134193.1|VEB64354.1|628015_628522_+|Putative-cytosolic-protein
MSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>LR134193.1|VEB64355.1|629020_630031_+|Alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKIRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>LR134193.1|VEB64356.1|630107_630215_+|Uncharacterised-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>LR134193.1|VEB64357.1|630307_630724_+|Uncharacterized-beta-barrel-protein-ywiB
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>LR134193.1|VEB64358.1|630720_632382_+|Arginyl-tRNA-synthetase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>LR134193.1|VEB64359.1|632715_633351_+|endonuclease-III-domain-protein
MLGTDELYKLLYRHMGPQNWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELSIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGELRKELLSLKGIGSETADVLLVYIFGRIVFIPDSYTRKIYDKLGYENTKSYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>LR134193.1|VEB64360.1|633723_634611_+|Periplasmic-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNHKQGSDDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK

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Crispr_ID: LR134193_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134193_4

1979028-1979117

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGCCTGTAGAATTTCTTTT	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of LR134193_4

>merge|LR134193|4|1979028-1979117|CRISPRCasFinder
CCCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAATTTCTTTT

>LR134193|4|4|1979028-1979117|CRISPRCasFinder
CCCCAACTTGCATTGCCTGTAGAATTTCTTTT	CGAAATTCTCTGTGTTGGGGCCCACA
CCCCAACTTGCATTGCCTGTAGAATTTCTTTT

Protein	Signature genes	Signature genes Name	Protein_function
LR134193.1\|VEB66506.1\|1972803_1973268_+\|Low-molecular-weight-protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|319971
LR134193.1\|VEB66524.1\|1985327_1986398_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
LR134193.1\|VEB66512.1\|1976816_1977518_-\|Transporter-yvqF	unknown	unknown	gnl\|CDD\|227100
LR134193.1\|VEB66527.1\|1987344_1988706_-\|RNA-methyltransferase,-TrmA-family	unknown	unknown	gnl\|CDD\|225174
LR134193.1\|VEB66503.1\|1971197_1972445_-\|aminopeptidase-PepS	unknown	unknown	gnl\|CDD\|376723
LR134193.1\|VEB66523.1\|1984705_1985260_+\|DNA-polymerase-III-polC-type	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
LR134193.1\|VEB66516.1\|1979422_1980409_+\|Integral-membrane-protein	unknown	unknown	gnl\|CDD\|226614
LR134193.1\|VEB66519.1\|1981477_1982209_-\|CobB/CobQ-like-glutamine-amidotransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225974
LR134193.1\|VEB66510.1\|1975157_1975787_-\|Two-component-transcriptional-regulator-VraR,-LuxR-family	unknown	unknown	gnl\|CDD\|225107
LR134193.1\|VEB66508.1\|1973827_1975045_+\|ribonuclease-BN	unknown	unknown	gnl\|CDD\|224214
LR134193.1\|VEB66511.1\|1975776_1976820_-\|Sensor-histidine-kinase-VraS	unknown	unknown	gnl\|CDD\|226951
LR134193.1\|VEB66522.1\|1983815_1984316_+\|Ferritin-like-protein-2	unknown	unknown	gnl\|CDD\|224445
LR134193.1\|VEB66505.1\|1972456_1972663_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|227177
LR134193.1\|VEB66528.1\|1988786_1989734_-\|Transcription-regulator-(contains-diacylglycerol-kinase-catalytic-domain)	unknown	unknown	gnl\|CDD\|183982
LR134193.1\|VEB66515.1\|1978135_1978894_-\|Methionine-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
LR134193.1\|VEB66507.1\|1973274_1973550_+\|exported-protein	unknown	unknown	unknown
LR134193.1\|VEB66514.1\|1977532_1977919_-\|putative-staphylococcal-protein	unknown	unknown	unknown
LR134193.1\|VEB66520.1\|1982210_1983524_-\|UDP-N-acetylmuramoylalanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|223840
LR134193.1\|VEB66525.1\|1986644_1987175_-\|Permease	unknown	unknown	gnl\|CDD\|378690
LR134193.1\|VEB66517.1\|1980839_1981253_-\|Uncharacterised-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
LR134193.1\|VEB66506.1\|1972803_1973268_+\|Low-molecular-weight-protein-tyrosine-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
LR134193.1\|VEB66524.1\|1985327_1986398_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
LR134193.1\|VEB66512.1\|1976816_1977518_-\|Transporter-yvqF	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
LR134193.1\|VEB66527.1\|1987344_1988706_-\|RNA-methyltransferase,-TrmA-family	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
LR134193.1\|VEB66503.1\|1971197_1972445_-\|aminopeptidase-PepS	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
LR134193.1\|VEB66523.1\|1984705_1985260_+\|DNA-polymerase-III-polC-type	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
LR134193.1\|VEB66519.1\|1981477_1982209_-\|CobB/CobQ-like-glutamine-amidotransferase-domain-containing-protein	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
LR134193.1\|VEB66510.1\|1975157_1975787_-\|Two-component-transcriptional-regulator-VraR,-LuxR-family	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.75115e-79
LR134193.1\|VEB66508.1\|1973827_1975045_+\|ribonuclease-BN	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
LR134193.1\|VEB66511.1\|1975776_1976820_-\|Sensor-histidine-kinase-VraS	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
LR134193.1\|VEB66522.1\|1983815_1984316_+\|Ferritin-like-protein-2	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
LR134193.1\|VEB66505.1\|1972456_1972663_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.82008e-26
LR134193.1\|VEB66516.1\|1979422_1980409_+\|Integral-membrane-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
LR134193.1\|VEB66515.1\|1978135_1978894_-\|Methionine-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
LR134193.1\|VEB66520.1\|1982210_1983524_-\|UDP-N-acetylmuramoylalanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.37755e-99
LR134193.1\|VEB66525.1\|1986644_1987175_-\|Permease	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.92343e-11
LR134193.1\|VEB66528.1\|1988786_1989734_-\|Transcription-regulator-(contains-diacylglycerol-kinase-catalytic-domain)	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0

>LR134193.1|VEB66515.1|1978135_1978894_-|Methionine-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>LR134193.1|VEB66514.1|1977532_1977919_-|putative-staphylococcal-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>LR134193.1|VEB66512.1|1976816_1977518_-|Transporter-yvqF
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>LR134193.1|VEB66511.1|1975776_1976820_-|Sensor-histidine-kinase-VraS
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>LR134193.1|VEB66510.1|1975157_1975787_-|Two-component-transcriptional-regulator-VraR,-LuxR-family
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>LR134193.1|VEB66508.1|1973827_1975045_+|ribonuclease-BN
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>LR134193.1|VEB66507.1|1973274_1973550_+|exported-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>LR134193.1|VEB66506.1|1972803_1973268_+|Low-molecular-weight-protein-tyrosine-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>LR134193.1|VEB66505.1|1972456_1972663_-|Uncharacterized-protein-conserved-in-bacteria
MAMTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>LR134193.1|VEB66503.1|1971197_1972445_-|aminopeptidase-PepS
MTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGETVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>LR134193.1|VEB66516.1|1979422_1980409_+|Integral-membrane-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>LR134193.1|VEB66517.1|1980839_1981253_-|Uncharacterised-protein
MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>LR134193.1|VEB66519.1|1981477_1982209_-|CobB/CobQ-like-glutamine-amidotransferase-domain-containing-protein
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>LR134193.1|VEB66520.1|1982210_1983524_-|UDP-N-acetylmuramoylalanyl-D-glutamate--2,-6-diaminopimelate-ligase
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>LR134193.1|VEB66522.1|1983815_1984316_+|Ferritin-like-protein-2
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>LR134193.1|VEB66523.1|1984705_1985260_+|DNA-polymerase-III-polC-type
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>LR134193.1|VEB66524.1|1985327_1986398_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>LR134193.1|VEB66525.1|1986644_1987175_-|Permease
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLFLLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>LR134193.1|VEB66527.1|1987344_1988706_-|RNA-methyltransferase,-TrmA-family
MQAIAKNDIKMGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKFNDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>LR134193.1|VEB66528.1|1988786_1989734_-|Transcription-regulator-(contains-diacylglycerol-kinase-catalytic-domain)
MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE

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Crispr_ID: LR134193_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134193_5

2307462-2307586

Orphan

Consensus_repeat	Method
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134193_5

>merge|LR134193|5|2307462-2307586|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCAATGATTTCCCATGATTTTTTAGTATTTTCTTTTGAGTTACTCGAAAATTATCCTCTTTACTCGAAAGCTCACAAAACGCTTGATATCA

>LR134193|5|5|2307462-2307586|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA	ATGATTTCCCATGATTTTTTAGTATTTTCTTTTGAGTTACTCGAAAATTAT
CCTCTTTACTCGAAAGCTCACAAAACGCTTGATATCA

Protein	Signature genes	Signature genes Name	Protein_function
LR134193.1\|VEB67038.1\|2309881_2310688_-\|Transmembrane-component-of-general-energizing-module-of-ECF-transporters	unknown	unknown	gnl\|CDD\|223692
LR134193.1\|VEB67044.1\|2311534_2312344_-\|cobalt-import-ATP-binding-protein	unknown	unknown	gnl\|CDD\|184207
LR134193.1\|VEB67054.1\|2314285_2314675_-\|30S-ribosomal-protein-S11	unknown	unknown	gnl\|CDD\|180007
LR134193.1\|VEB66999.1\|2294495_2294912_-\|transcriptional-regulator,-MerR-family	unknown	unknown	gnl\|CDD\|133384
LR134193.1\|VEB67005.1\|2297805_2298660_-\|Peptidase,-M23/M37-family	unknown	unknown	gnl\|CDD\|223810
LR134193.1\|VEB66996.1\|2293577_2294426_-\|oxidoreductase,-aldo/keto-reductase-family	unknown	unknown	gnl\|CDD\|381359
LR134193.1\|VEB67008.1\|2299532_2299811_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134193.1\|VEB67041.1\|2310677_2311538_-\|ATPase-component-of-general-energizing-module-of-ECF-transporters	unknown	unknown	gnl\|CDD\|184205
LR134193.1\|VEB67028.1\|2307984_2308383_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
LR134193.1\|VEB67017.1\|2301570_2302386_-\|hydrolase	unknown	unknown	gnl\|CDD\|319792
LR134193.1\|VEB67014.1\|2299820_2301338_+\|glycosyl-transferases-group-1-family-protein	unknown	unknown	gnl\|CDD\|340855
LR134193.1\|VEB67031.1\|2308396_2308834_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
LR134193.1\|VEB67057.1\|2314698_2315064_-\|30S-ribosomal-protein-S13	unknown	unknown	gnl\|CDD\|235358
LR134193.1\|VEB67024.1\|2303484_2304189_-\|alpha-acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
LR134193.1\|VEB67020.1\|2302680_2303106_+\|Truncated-cell-surface-protein-map-w	unknown	unknown	gnl\|CDD\|367591
LR134193.1\|VEB67050.1\|2313266_2314211_-\|DNA-directed-RNA-polymerase-alpha-subunit	unknown	unknown	gnl\|CDD\|235359
LR134193.1\|VEB67025.1\|2304225_2305890_-\|Acetolactate-synthase,-catabolic	unknown	unknown	gnl\|CDD\|236312
LR134193.1\|VEB67047.1\|2312881_2313250_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
LR134193.1\|VEB67002.1\|2295319_2297746_+\|Hyaluronate-lyase-precursor	unknown	unknown	gnl\|CDD\|238517
LR134193.1\|VEB67034.1\|2309073_2309877_-\|tRNA-pseudouridine-synthase-A	unknown	unknown	gnl\|CDD\|234577

Protein	Function_ID	Function_description	E-value
LR134193.1\|VEB67038.1\|2309881_2310688_-\|Transmembrane-component-of-general-energizing-module-of-ECF-transporters	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.16976e-49
LR134193.1\|VEB67044.1\|2311534_2312344_-\|cobalt-import-ATP-binding-protein	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
LR134193.1\|VEB67054.1\|2314285_2314675_-\|30S-ribosomal-protein-S11	gnl\|CDD\|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	2.01588e-89
LR134193.1\|VEB67020.1\|2302680_2303106_+\|Truncated-cell-surface-protein-map-w	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	2.66977e-34
LR134193.1\|VEB67005.1\|2297805_2298660_-\|Peptidase,-M23/M37-family	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	7.61272e-24
LR134193.1\|VEB66996.1\|2293577_2294426_-\|oxidoreductase,-aldo/keto-reductase-family	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	4.21774e-150
LR134193.1\|VEB67031.1\|2308396_2308834_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.37368e-100
LR134193.1\|VEB67041.1\|2310677_2311538_-\|ATPase-component-of-general-energizing-module-of-ECF-transporters	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
LR134193.1\|VEB67028.1\|2307984_2308383_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82
LR134193.1\|VEB67017.1\|2301570_2302386_-\|hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.0464e-100
LR134193.1\|VEB67014.1\|2299820_2301338_+\|glycosyl-transferases-group-1-family-protein	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	5.20492e-61
LR134193.1\|VEB67002.1\|2295319_2297746_+\|Hyaluronate-lyase-precursor	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
LR134193.1\|VEB67057.1\|2314698_2315064_-\|30S-ribosomal-protein-S13	gnl\|CDD\|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	2.16257e-78
LR134193.1\|VEB67024.1\|2303484_2304189_-\|alpha-acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	9.58959e-119
LR134193.1\|VEB67050.1\|2313266_2314211_-\|DNA-directed-RNA-polymerase-alpha-subunit	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	1.89947e-175
LR134193.1\|VEB67025.1\|2304225_2305890_-\|Acetolactate-synthase,-catabolic	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
LR134193.1\|VEB67047.1\|2312881_2313250_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
LR134193.1\|VEB66999.1\|2294495_2294912_-\|transcriptional-regulator,-MerR-family	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.85601e-41
LR134193.1\|VEB67034.1\|2309073_2309877_-\|tRNA-pseudouridine-synthase-A	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	5.95917e-120

>LR134193.1|VEB67025.1|2304225_2305890_-|Acetolactate-synthase,-catabolic
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPAESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGLISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELDTQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISDKVDEPFINQQHLDELEQLRAHIDQETGIKATHEEGILHPVEIIESMQKVLTDETTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>LR134193.1|VEB67024.1|2303484_2304189_-|alpha-acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIHDEDFTNANIDYKDISDEIREAE
>LR134193.1|VEB67020.1|2302680_2303106_+|Truncated-cell-surface-protein-map-w
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>LR134193.1|VEB67017.1|2301570_2302386_-|hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>LR134193.1|VEB67014.1|2299820_2301338_+|glycosyl-transferases-group-1-family-protein
MTTYMLMYSIPEKAGGITSVMLNRSKLLAEKGYSCALLTLDDKNYDPLRAKLTNSGRLHKQVKIVNLYEELKMLYDVENTEIENKNMQTFEKLNLLNQEGFYIQKDEYEEKKYARYFKDNHYIMYKKWINGQLSHIDYFQNRKRFKRHVFQNKILRKEITFNDKNKMSEVKYLSNDGFCYLSYWYGDNENIVNIFYFDKNSKEVLNFKNNKAFHSYWLDKNLTSNDVLILDGIGTYHKVENMQNNDIKKIFTIHTNHFMSPYSYGAEIKPEFRNMLLNLKKLDTLVVLTKEQKDDIIKQFGDYNNIKVIPNAISFEENLTQNIREKNSIIVLQRFVAMKNITHIISAINIVRKKVKDVKLHIYGTGTQKENYTKLIKKLKLQDNVFIHDYAFDIRALYTKTSLSVLTSDYEGLPMSLLEAMSYGVPVISYPINYGPKSIIQNNINGIITKKKDNINELAKKIIHVLKKETLISQFSENARTTIKTNFSYEAVSKKWIELIDEKSQ
>LR134193.1|VEB67008.1|2299532_2299811_+|Uncharacterised-protein
MTLNEYNYNNELILKLNKIEVQKNNEKISEVFKDYEILKPKIVFNGSNPYLALNHIIVAEIENYSSLETFSKIYVDEDYYYNYGELIIKCKK
>LR134193.1|VEB67005.1|2297805_2298660_-|Peptidase,-M23/M37-family
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWHFRKLFKSYTRQSDVHELKVCTQNDGTMEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNKGKVNTDYFYFGKDIIAPANGTVEKVANGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>LR134193.1|VEB67002.1|2295319_2297746_+|Hyaluronate-lyase-precursor
MTYRMKKWQKISTITLLMAGVITFNDSEFRSVDKHQIAVADTNVQTTDYEKLRNTWLNVNYGYNQYDENNDAMKKKFEATEKEATNLLSSMKTESDRKYLWENSKDLDTKSADMTRTYRNIEKIAEAMKHKNTKLNTPDNKNKVKDALEWLHKNAYGKEPTDKVKELTENFKNKTSRNTNLNWWDYEIGTPRALTNTLILLNGDISSDEKKKYTAPIKTFAPESDKILSSVGQPEQAKGGNLVDIAKVKLLESIIEEDTTMMKESIDAFNKVFTYVQSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETSFKDSNQNDTTLKSWIDEGFMPLIYKGEMMDLSRGRAISRENETSHSVSATVMKSLLRLSDAMDDSTKAKYKQIVKTSVKSDSSYKQNDYLSSYSDISKMKSLMEDSTISTNDLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINNENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTIENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKTNGYTLYTDDKQTTASDNQDTNSVFLESTNKPKNNIGYHFLNKSKITVKKESHTGKWSDINKSQKSEDKTDEYYEVTQKHSDKDNKYGYVLYPGITKDNFKSKASQVTVVKQDDDFHVVKDNESVWAGVNYSDSAKTFEINGTKVEVKAKGMFILKKKNDKTYECSFYNPESTNPASDIESKISMTGYSITNKDTSTTNESGVRFELTK
>LR134193.1|VEB66999.1|2294495_2294912_-|transcriptional-regulator,-MerR-family
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNHDANVERLWERK
>LR134193.1|VEB66996.1|2293577_2294426_-|oxidoreductase,-aldo/keto-reductase-family
MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDTAQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYLDLVLIHQPYNDVYGSWRALEELKENGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEINPFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLVERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALTSRELDV
>LR134193.1|VEB67028.1|2307984_2308383_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>LR134193.1|VEB67031.1|2308396_2308834_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKATYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>LR134193.1|VEB67034.1|2309073_2309877_-|tRNA-pseudouridine-synthase-A
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
>LR134193.1|VEB67038.1|2309881_2310688_-|Transmembrane-component-of-general-energizing-module-of-ECF-transporters
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWVFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVQRTSYRQLKWQLRDTLSLIMIIPFAIILFVLKYSGV
>LR134193.1|VEB67041.1|2310677_2311538_-|ATPase-component-of-general-energizing-module-of-ECF-transporters
MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>LR134193.1|VEB67044.1|2311534_2312344_-|cobalt-import-ATP-binding-protein
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTAIEIFDHAEELTTIGLDLPFPIKINQMLGYQTSFLTYEGLVDQL
>LR134193.1|VEB67047.1|2312881_2313250_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
>LR134193.1|VEB67050.1|2313266_2314211_-|DNA-directed-RNA-polymerase-alpha-subunit
MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
>LR134193.1|VEB67054.1|2314285_2314675_-|30S-ribosomal-protein-S11
MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
>LR134193.1|VEB67057.1|2314698_2315064_-|30S-ribosomal-protein-S13
MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK

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Crispr_ID: LR134193_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134193_6

2549961-2550044

Orphan

Consensus_repeat	Method
ACAGACAATGCAAGTTGGGGTGTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134193_6

>merge|LR134193|6|2549961-2550044|CRISPRCasFinder
ACAGACAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCCACAGACAATGCAAGTTGGGGTGGGA

>LR134193|6|6|2549961-2550044|CRISPRCasFinder
ACAGACAATGCAAGTTGGGGTGTGG	GCCCCAACAAAGAGAAATTGGATTCCCAATTTCC
ACAGACAATGCAAGTTGGGGTGGGA

Protein	Signature genes	Signature genes Name	Protein_function
LR134193.1\|VEB68069.1\|2548945_2549695_+\|membrane-protein	unknown	unknown	unknown
LR134193.1\|VEB68095.1\|2557768_2558587_-\|nicotianamine-synthase	unknown	unknown	gnl\|CDD\|176222
LR134193.1\|VEB68091.1\|2556474_2557776_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|226839
LR134193.1\|VEB68041.1\|2539465_2540818_+\|Carboxylesterase-type-B	unknown	unknown	gnl\|CDD\|225181
LR134193.1\|VEB68047.1\|2542460_2543237_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223467
LR134193.1\|VEB68084.1\|2553785_2554721_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	unknown	unknown	gnl\|CDD\|223674
LR134193.1\|VEB68075.1\|2551365_2552115_-\|nickel-transport-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
LR134193.1\|VEB68044.1\|2540879_2542067_-\|chloramphenicol-resistance-protein	unknown	unknown	gnl\|CDD\|225371
LR134193.1\|VEB68072.1\|2550160_2551354_-\|Antibiotic-resistance-protein	unknown	unknown	gnl\|CDD\|341042
LR134193.1\|VEB68065.1\|2547173_2548751_-\|Ferredoxin-dependent-glutamate-synthase	unknown	unknown	gnl\|CDD\|223147
LR134193.1\|VEB68053.1\|2544237_2545314_-\|endoglucanase-M	unknown	unknown	gnl\|CDD\|349906
LR134193.1\|VEB68078.1\|2552107_2552923_-\|Oligopeptide-transporter-putative-ATPase-domain-protein	unknown	unknown	gnl\|CDD\|223521
LR134193.1\|VEB68056.1\|2545668_2545935_-\|addiction-module-toxin	unknown	unknown	gnl\|CDD\|226600
LR134193.1\|VEB68101.1\|2560297_2560663_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134193.1\|VEB68088.1\|2554733_2556332_-\|Oligopeptide-transporter-putative-substrate-binding-domain-protein	unknown	unknown	gnl\|CDD\|274072
LR134193.1\|VEB68059.1\|2545934_2546192_-\|prevent-host-death-family-protein	unknown	unknown	gnl\|CDD\|225072
LR134193.1\|VEB68062.1\|2546550_2547006_+\|lipoprotein	unknown	unknown	gnl\|CDD\|227145
LR134193.1\|VEB68050.1\|2543229_2543892_-\|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein	unknown	unknown	gnl\|CDD\|226970
LR134193.1\|VEB68081.1\|2552919_2553789_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	unknown	unknown	gnl\|CDD\|224094
LR134193.1\|VEB68098.1\|2558597_2559419_-\|Putative-Similar-to-diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|223331

Protein	Function_ID	Function_description	E-value
LR134193.1\|VEB68053.1\|2544237_2545314_-\|endoglucanase-M	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	4.62851e-171
LR134193.1\|VEB68095.1\|2557768_2558587_-\|nicotianamine-synthase	gnl\|CDD\|176222	cd08261, Zn_ADH7, Alcohol dehydrogenases of the MDR family. This group contains members identified as related to zinc-dependent alcohol dehydrogenase and other members of the MDR family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group includes various activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0.000103671
LR134193.1\|VEB68091.1\|2556474_2557776_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|226839	COG4408, COG4408, Uncharacterized protein conserved in bacteria [Function unknown].	0
LR134193.1\|VEB68041.1\|2539465_2540818_+\|Carboxylesterase-type-B	gnl\|CDD\|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	9.64084e-175
LR134193.1\|VEB68047.1\|2542460_2543237_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223467	COG0390, COG0390, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.19402e-101
LR134193.1\|VEB68084.1\|2553785_2554721_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.85614e-99
LR134193.1\|VEB68072.1\|2550160_2551354_-\|Antibiotic-resistance-protein	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.36995e-79
LR134193.1\|VEB68044.1\|2540879_2542067_-\|chloramphenicol-resistance-protein	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	7.53591e-90
LR134193.1\|VEB68075.1\|2551365_2552115_-\|nickel-transport-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.93009e-106
LR134193.1\|VEB68065.1\|2547173_2548751_-\|Ferredoxin-dependent-glutamate-synthase	gnl\|CDD\|223147	COG0069, GltB, Glutamate synthase domain 2 [Amino acid transport and metabolism].	5.04566e-175
LR134193.1\|VEB68078.1\|2552107_2552923_-\|Oligopeptide-transporter-putative-ATPase-domain-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.18808e-119
LR134193.1\|VEB68056.1\|2545668_2545935_-\|addiction-module-toxin	gnl\|CDD\|226600	COG4115, COG4115, Uncharacterized protein conserved in bacteria [Function unknown].	3.49994e-30
LR134193.1\|VEB68088.1\|2554733_2556332_-\|Oligopeptide-transporter-putative-substrate-binding-domain-protein	gnl\|CDD\|274072	TIGR02294, Nickel-binding_periplasmic_protein, nickel ABC transporter, nickel/metallophore periplasmic binding protein. Members of this family are periplasmic nickel-binding proteins of nickel ABC transporters. Most appear to be lipoproteins. This protein was previously (circa 2003) thought to mediate binding to nickel through water molecules, but is now thought to involve a chelating organic molecule, perhaps butane-1,2,4-tricarboxylate, acting as a metallophore. [Transport and binding proteins, Cations and iron carrying compounds].	0
LR134193.1\|VEB68059.1\|2545934_2546192_-\|prevent-host-death-family-protein	gnl\|CDD\|225072	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	1.00456e-14
LR134193.1\|VEB68062.1\|2546550_2547006_+\|lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	1.02133e-51
LR134193.1\|VEB68050.1\|2543229_2543892_-\|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein	gnl\|CDD\|226970	COG4619, COG4619, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	1.21101e-118
LR134193.1\|VEB68081.1\|2552919_2553789_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.01187e-84
LR134193.1\|VEB68098.1\|2558597_2559419_-\|Putative-Similar-to-diaminopimelate-epimerase	gnl\|CDD\|223331	COG0253, DapF, Diaminopimelate epimerase [Amino acid transport and metabolism].	1.05454e-73

>LR134193.1|VEB68069.1|2548945_2549695_+|membrane-protein
MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVFLTFGLVAIFTQQAPWDFSFPISMNISYLLAVILSLAIFRRMHEDAFIPMIRSQIVASTKYKWHILISFTLSIVLFLLLNHFEIFALNVDSFTVFDIYPLIREYGSISLIAIFSLTIILNTLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILASSATYLYLKSNRNFMVSYFYQLAVILVLHIFM
>LR134193.1|VEB68065.1|2547173_2548751_-|Ferredoxin-dependent-glutamate-synthase
MTFLTVMQFIVNIIIIGFLLTVIVIGLIWLIKDKRQSQHSVLRNYPLLARIRYISEKMGPELRQYLFSGDNEGKPFSRNDYKNIVLAGKYNSRMTSFGTTKDYQDGFYIQNTMFPMQRNEISVDNTTLLSTFIYKIANERLFSREEYRVPTKIDPYYLSDDHAIKLGEHLKYPFILKRIVGQSGMSYGALGKNAITALSKGLAKAGTWMNTGEGGLSEYHLKGNGDIIFQIGPGLFGVRDKEGNFSEGLFKEVAQLSNVRAFELKLAQGAKTRGGHMEAEKVNEEIAKIRNVEPYKTINSPNRYEFIHNAEDLIRFVDQLQQLGQKPVGFKIVVSKVSEIETLVRTMVELDKYPSFITIDGGEGGTGATFQELQDGVGLPLFTALPIVSGMLEKYGIRDKVKLAASGKLVTPDKIAIALGLGADFVNIARGMMISVGCIMSQQCHMNTCPVGVATTDAKKEKALIVGEKQYRVTNYVTSLHEGLFNIAAAVGVSSPTEITADHIVYRKIDGELQTIHDYKLKLIS
>LR134193.1|VEB68062.1|2546550_2547006_+|lipoprotein
MKKLCSLIVVALVCIIALSACGKEQTKTYEGDVSGKHVLTSITYKNDKVLKQSTINTIKYDDLGMDKDEAKKLFAKSESIFKDLKGVKYKVDYKDKKAIEHLDIDYTEVDMKKLNKRLGVSTKENKDISFEKLEKQLKHRGLKEKDKMDDK
>LR134193.1|VEB68059.1|2545934_2546192_-|prevent-host-death-family-protein
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDIDWDNL
>LR134193.1|VEB68056.1|2545668_2545935_-|addiction-module-toxin
MSNYTVKIKNSAKSDLKKIKHSYLKKSFLEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLILSAWSHYD
>LR134193.1|VEB68053.1|2544237_2545314_-|endoglucanase-M
MNQSVKLLKHLTDVNGIAGYEMQVKEAMRNYIEPVSDQIIEDNLGGIFGKKNAENGQYSIMISGHMDEVGFMVTKIDKHGFISFTPVGGWWNQVMLSQKVTITTDSGKEIRGIIGSKPPHVLTPEERKKPMEIKNMFIDIGVSSKGEAEEAGVEVGNMVTPYSEFEVLANNKYLTAKAFDNRYGCALAIEVLQRLKDKNIGINLYSGATVQEEVGLRGAKVAANTIKPDLAIAVDVGIAYDTPGMSGQTSDSKLGGGPVVIMMDATSIAHQGLRKHIKDVAKKHNIEVQWDTTPGGGTDAGSIHVANEGIPTMTIGVTLRYMHSNVSVLNVDDYENSIRLVTEIVRSLNDETYKNIMW
>LR134193.1|VEB68050.1|2543229_2543892_-|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein
MLLEIKDLVYEASDRVILNHINLKVDKGETIAIIGPSGSGKSTFQKIICNLISPTSGTLYFKDKPYDDYEPEILRRHISYLMQQSDLFGETIEDNMIFPSLARNDKFDKKRAKQLIKDVGLGHYQLSSKIEHMSGGERQRIAIARQLMYTPDILLLDESTSALDIHNKEKIENIIFKLADQGVAIMWITHSDDQSMRHFQKRITIVDGQISNIEELNQHE
>LR134193.1|VEB68047.1|2542460_2543237_-|ABC-transporter-ATP-binding-protein
MSNTALGLTALLLVIPIIISYKEGLHIIKDLIVATLRAVVQLIILGFLLHYIFKINDKWLLVLCVFVIIVNASWNTISRSSPVMHHVFWISFVAIFVGTALPLAGTIATGAIQFTANEVIPIGGMLANNGLIAINLAYQNLDRAFVQDGTNIESKLSLAATPKLASKGAIRESIRLAIVPTIDSVKTYGLVSIPGMMTGLIIGGVPPLQAIKFQLLVVFIHTTATIMSALIATYLSYGQFFNARHQLVARNTDVKSES
>LR134193.1|VEB68044.1|2540879_2542067_-|chloramphenicol-resistance-protein
MSIMRLFTFILSIFIVGMVEMMVAGIMNLMSQDLHVSEAVVGQLVTMYALTFAICGPILVKLTNRFSSRPVLLWTLLIFIIGNGIIAVAPNFSILVVGRIISSAAAALIIVKVLAITAMLSAPKNRGKMIGLVYTGFSGANVFGVPIGTVIGDLVGWRYTFLFLIIVSIIVGFLMMIYLPKDQEIQRGSVNHEAPSHENHVTSKILRPAEVAKYLIITFLVLIANSVTFVFINPLILSNGHDMSFVSLALLVNGIAGVIGTSLGGIFSDKITSKRWLMISVSIFIVMMLLMNLILPGSGLLLAGLFIWNIMQWSTNPAVQSGVIQHVEGDTSQVMSWNMSSLNAGIGVGGIIGGLVMTHVSVQAITYTSAIIGALGLIVVLTLKNNHYAKTFKSS
>LR134193.1|VEB68041.1|2539465_2540818_+|Carboxylesterase-type-B
MKINTTGGQIYGITQDRLDIFLGIPYAEPPVHDNRFKHSTLKTQWSEPIDATEIQPIPPQPDNKLEDFFSSQSATFTEHEDCLYLNIWKQHNDQSKKPVIIYFYGGSFENGHGTAELYQPAHLVQNNDIIVITCNYRLGALGYLDWSYFNKGFHSNNGLSDQINVIKWVHQFIESFGGDANNITLMGQSAGSMSILTLLKIPDIEPYFHKVVLLSGALRLDTLESARNKAQHFQKMMLDYIDTDDVTSLSTDDILMLMAKLKQSRGPSKGLDLIYAPIKTDYIQNNYPTTKPIFACYTKDEGDIYITSEQKKLSPQRFIDIMELNDIPLKYEDVQTAKQQSLAITHCYFKQPMKQFLQQLNIQDSNAQLWLAEFAWHDTSSAHYRSAYHILDMIFWFGNLQILSAHQYPITDHLKFLSRQMQNDLANFAKSGKMPWPIYHNERRYYRTYQ
>LR134193.1|VEB68072.1|2550160_2551354_-|Antibiotic-resistance-protein
MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVIGIVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARVMQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNISLFAIVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAVTVFAQFFKNKELLNSGIIMIVASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHPKYMVSVLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVGRNMLLGLFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPRPANSL
>LR134193.1|VEB68075.1|2551365_2552115_-|nickel-transport-ATP-binding-protein
MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESGSGKSTLSRMILGIEKPDKGCVTLNDHPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREILFEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKIEEQIPTSALHKSDNAYTRELIEKQLSF
>LR134193.1|VEB68078.1|2552107_2552923_-|Oligopeptide-transporter-putative-ATPase-domain-protein
MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGKSITCKSIIGLNPERLGVTGDITFDGKPMLSLSEAQLKKYRGKDIAMVMQQGSRAFDPSTTVGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLMIALALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIADRVVVMKNGQLIEHGTRESVLHHPKHVYTKYLLSTKKKINDHFKHVMRGDVHD
>LR134193.1|VEB68081.1|2552919_2553789_-|Oligopeptide-transporter-putative-membrane-permease-domain-protein
MIILKRLLQDKGAVVALGIIVLYVFLGLAAPLVTFYDPNHIDTANKFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRSVKKGVVQS
>LR134193.1|VEB68084.1|2553785_2554721_-|Oligopeptide-transporter-putative-membrane-permease-domain-protein
MFKFILKRIALMFPLVIVVSFMTFLLTYITNENPAVTILHAQGTPNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITLMLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYVLIVAVLFIIFNTLADIINALLNPRLREGAR
>LR134193.1|VEB68088.1|2554733_2556332_-|Oligopeptide-transporter-putative-substrate-binding-domain-protein
MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIGDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLSKKWDVSEDGKTYTFHLRDDVKFHDGTPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQIDDEGIFIPISHGSMTVVAPKDLEKVSFTQSQYELPFNEMQYK
>LR134193.1|VEB68091.1|2556474_2557776_-|Uncharacterized-protein-conserved-in-bacteria
MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLYQAYKKEKQFEVKIQNEAHQHLEGNFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQQLSLETLQSVKHVILISPTFGSQMIVEQFMSKFNKDIEVISFSTYLGDTRIVDKEAPNHVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPPLFMNDFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQAFRVPSVNLIQFMVKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYTAILIDPFSQPDENGHYFDFSAVPFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIKTPMIDQFLTRYEASCQAYKDMHQDQQLSSQFNTNLFEGDKALVTKFLEINRTLS
>LR134193.1|VEB68095.1|2557768_2558587_-|nicotianamine-synthase
MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYSEFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDNIEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV
>LR134193.1|VEB68098.1|2558597_2559419_-|Putative-Similar-to-diaminopimelate-epimerase
MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVCCEQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCSDLVQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVKQVTTEIQHLVESYVRKQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASIGVFNNYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE
>LR134193.1|VEB68101.1|2560297_2560663_-|Uncharacterised-protein
MLKEKESFRLLYQAIREIADKIGDNQLETNSVSLLLLDFDFEHEVFDELYLAILKYLNTVSIENISHSELLNLIENTIPEDREINTFVKNKIIIGFANNYFPELQVLANEIKSDMASSLKQ

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Crispr_ID: LR134193_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134193_7

2675790-2675871

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134193_7

>merge|LR134193|7|2675790-2675871|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>LR134193|7|7|2675790-2675871|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134193.1\|VEB68472.1\|2671078_2671780_-\|Immunodominant-staphylococcal-antigen-A-precursor	unknown	unknown	gnl\|CDD\|381607
LR134193.1\|VEB68485.1\|2674801_2675122_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134193.1\|VEB68532.1\|2683228_2684569_-\|ferrous-iron-transporter-protein-B	unknown	unknown	gnl\|CDD\|223447
LR134193.1\|VEB68481.1\|2673835_2674423_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
LR134193.1\|VEB68518.1\|2680021_2680852_+\|Esterase/Lipase	unknown	unknown	gnl\|CDD\|223669
LR134193.1\|VEB68506.1\|2677639_2678197_+\|Transcriptional-regulator,-TetR-family	unknown	unknown	gnl\|CDD\|224228
LR134193.1\|VEB68452.1\|2664710_2666204_-\|Phytoene-desaturase,-neurosporene-or-lycopene-producing-/-4,4-diapolycopene-oxidase	unknown	unknown	gnl\|CDD\|224154
LR134193.1\|VEB68514.1\|2678991_2680002_+\|5-carboxyvanillic-acid-decarboxylase	unknown	unknown	gnl\|CDD\|225070
LR134193.1\|VEB68493.1\|2675975_2676353_-\|glyoxalase	unknown	unknown	gnl\|CDD\|226134
LR134193.1\|VEB68461.1\|2666860_2667628_-\|Secretory-antigen-precursor-SsaA	unknown	unknown	gnl\|CDD\|226451
LR134193.1\|VEB68510.1\|2678189_2678894_+\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|187585
LR134193.1\|VEB68497.1\|2676369_2677191_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187561
LR134193.1\|VEB68528.1\|2682238_2683129_-\|Putative-GTPases-(G3E-family)	unknown	unknown	gnl\|CDD\|223597
LR134193.1\|VEB68465.1\|2667988_2669800_-\|O-acetyltransferase-oatA	unknown	unknown	gnl\|CDD\|224748
LR134193.1\|VEB68523.1\|2680992_2682018_+\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176191
LR134193.1\|VEB68476.1\|2672388_2673444_-\|membrane-spanning-protein	unknown	unknown	gnl\|CDD\|226167
LR134193.1\|VEB68501.1\|2677209_2677509_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|226806
LR134193.1\|VEB68489.1\|2675341_2675572_+\|putative-DUF896-containing-protein	unknown	unknown	gnl\|CDD\|226677
LR134193.1\|VEB68457.1\|2666196_2666649_-\|Glycosyl-4,4-diaponeurosporenoate-acyltransferase-precursor	unknown	unknown	unknown
LR134193.1\|VEB68469.1\|2670314_2670803_-\|Acetyltransferase,-GNAT-family	unknown	unknown	gnl\|CDD\|379228

Protein	Function_ID	Function_description	E-value
LR134193.1\|VEB68472.1\|2671078_2671780_-\|Immunodominant-staphylococcal-antigen-A-precursor	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	2.63325e-06
LR134193.1\|VEB68481.1\|2673835_2674423_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.60542e-07
LR134193.1\|VEB68518.1\|2680021_2680852_+\|Esterase/Lipase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.86854e-18
LR134193.1\|VEB68506.1\|2677639_2678197_+\|Transcriptional-regulator,-TetR-family	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.49706e-13
LR134193.1\|VEB68452.1\|2664710_2666204_-\|Phytoene-desaturase,-neurosporene-or-lycopene-producing-/-4,4-diapolycopene-oxidase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	3.14208e-132
LR134193.1\|VEB68514.1\|2678991_2680002_+\|5-carboxyvanillic-acid-decarboxylase	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	2.02807e-77
LR134193.1\|VEB68493.1\|2675975_2676353_-\|glyoxalase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.48638e-58
LR134193.1\|VEB68461.1\|2666860_2667628_-\|Secretory-antigen-precursor-SsaA	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	9.90876e-31
LR134193.1\|VEB68510.1\|2678189_2678894_+\|short-chain-dehydrogenase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.1238e-67
LR134193.1\|VEB68497.1\|2676369_2677191_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.51828e-85
LR134193.1\|VEB68532.1\|2683228_2684569_-\|ferrous-iron-transporter-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	5.10424e-93
LR134193.1\|VEB68465.1\|2667988_2669800_-\|O-acetyltransferase-oatA	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	3.4224e-84
LR134193.1\|VEB68523.1\|2680992_2682018_+\|alcohol-dehydrogenase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.78714e-97
LR134193.1\|VEB68476.1\|2672388_2673444_-\|membrane-spanning-protein	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
LR134193.1\|VEB68501.1\|2677209_2677509_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	1.97434e-38
LR134193.1\|VEB68489.1\|2675341_2675572_+\|putative-DUF896-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31
LR134193.1\|VEB68528.1\|2682238_2683129_-\|Putative-GTPases-(G3E-family)	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.21918e-76
LR134193.1\|VEB68469.1\|2670314_2670803_-\|Acetyltransferase,-GNAT-family	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.33488e-11

>LR134193.1|VEB68489.1|2675341_2675572_+|putative-DUF896-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>LR134193.1|VEB68485.1|2674801_2675122_+|Uncharacterised-protein
MSETDESQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHIIIACGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHMMSFDNDYFFAQLRHPVL
>LR134193.1|VEB68481.1|2673835_2674423_+|TetR-family-transcriptional-regulator
MLGSEQMMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>LR134193.1|VEB68476.1|2672388_2673444_-|membrane-spanning-protein
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>LR134193.1|VEB68472.1|2671078_2671780_-|Immunodominant-staphylococcal-antigen-A-precursor
MKKTIMASSLAVALGVTGYAASTGHEAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>LR134193.1|VEB68469.1|2670314_2670803_-|Acetyltransferase,-GNAT-family
MTINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIEHNYLNSGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDEGYRNLKIGKKLLDKVIMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNLKG
>LR134193.1|VEB68465.1|2667988_2669800_-|O-acetyltransferase-oatA
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYVIEIVLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>LR134193.1|VEB68461.1|2666860_2667628_-|Secretory-antigen-precursor-SsaA
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWASAAASSGYTVNNTPKAGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>LR134193.1|VEB68457.1|2666196_2666649_-|Glycosyl-4,4-diaponeurosporenoate-acyltransferase-precursor
MYWLIVQLNIANLGTRIPDKYFRQKHIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMITNVPIIIVQRYNRPRLTQLLRILKRRGERHD
>LR134193.1|VEB68452.1|2664710_2666204_-|Phytoene-desaturase,-neurosporene-or-lycopene-producing-/-4,4-diapolycopene-oxidase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKIFEYSNKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNVILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK
>LR134193.1|VEB68493.1|2675975_2676353_-|glyoxalase
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>LR134193.1|VEB68497.1|2676369_2677191_-|NAD-dependent-epimerase/dehydratase-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDSDSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSSVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQDYNK
>LR134193.1|VEB68501.1|2677209_2677509_-|Uncharacterized-protein-conserved-in-bacteria
MSLNKEQRRITAEELQAHFEASTLSVQMIAEKLNVTTEDVEKALAMKAPLGIFSHQLQRFIHLVWDVRNVINDNIKENGQTPEPYTYLKGEKEDYWFLR
>LR134193.1|VEB68506.1|2677639_2678197_+|Transcriptional-regulator,-TetR-family
MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSDYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFNFYYDLFKSDDDIYKKFKTDMLLQALSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>LR134193.1|VEB68510.1|2678189_2678894_+|short-chain-dehydrogenase
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIDADGPTGTFINGDGEMPW
>LR134193.1|VEB68514.1|2678991_2680002_+|5-carboxyvanillic-acid-decarboxylase
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLDVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>LR134193.1|VEB68518.1|2680021_2680852_+|Esterase/Lipase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKYNDKITLLNGTDSRGSFPQDVNFYINNETGIPIVDIPGGHLGYIQKPEGFADVLLNMWS
>LR134193.1|VEB68523.1|2680992_2682018_+|alcohol-dehydrogenase
MKAIQIKKYNKNRDVQIRDITIPEIKSTEVLVKVAYAAINPLENLTINGSVKLIQNYKMPQTIGNELTGTIVKVGSKVEDYKLGDKIYSRLPIDRIGAFAEYVSIESNAIAKLPKNLNLKTGAAVPLTGLTAYQAITEELKAIPGKTLFIPGGSGSFGQMAVPIAKSLGLKVIVSGSPRLKDQFLAKGVDQYIDYKTENYCEVLSDIDYVIDTLGPNEFDKELSVMKPGGTIVSLINAPNKAFAVKNNFSPFKKLLFGLAGKKFDKKAQKKSIDYRFIFVRSDGEQLKILNKIIEQNNIIPDIDDHIFTIDEIDKALDYTFNHHTNGKVLIRIDNSDNTIY
>LR134193.1|VEB68528.1|2682238_2683129_-|Putative-GTPases-(G3E-family)
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVVDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTVTSDNKHESLHKTINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>LR134193.1|VEB68532.1|2683228_2684569_-|ferrous-iron-transporter-protein-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLNATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGFKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNNQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMLTSLSLVIGVGIIVKIVMLII

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	401320-401347	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	625103-625130	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	795039-795066	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1035071-1035098	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1325157-1325184	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1413904-1413931	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1657236-1657263	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1871735-1871762	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1980500-1980527	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	2333764-2333791	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	2675774-2675801	0	1.0
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	285097-285125	0	1.0
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	804018-804046	0	1.0
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1009095-1009123	0	1.0
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	2514020-2514048	0	1.0
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	2514076-2514104	0	1.0
LR134193_4	4.1\|1979060\|26\|LR134193\|CRISPRCasFinder	1979060-1979085	26	LR134193.1	795059-795084	0	1.0
LR134193_4	4.1\|1979060\|26\|LR134193\|CRISPRCasFinder	1979060-1979085	26	LR134193.1	1980520-1980545	0	1.0
LR134193_4	4.1\|1979060\|26\|LR134193\|CRISPRCasFinder	1979060-1979085	26	LR134193.1	2333784-2333809	0	1.0
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	361227-361254	1	0.964
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	909337-909364	1	0.964
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	2182500-2182528	1	0.966
LR134193_2	2.1\|625141\|28\|LR134193\|CRISPRCasFinder	625141-625168	28	LR134193.1	1979119-1979146	1	0.964
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1111327-1111354	2	0.929
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1776729-1776756	2	0.929
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	1989850-1989877	2	0.929
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	2344572-2344599	2	0.929
LR134193_1	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	LR134193.1	2792638-2792665	2	0.929
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	361171-361199	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	625215-625243	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1035128-1035156	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1111269-1111297	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1325215-1325243	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1413961-1413989	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1657180-1657208	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1657293-1657321	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1671768-1671796	2	0.931
LR134193_1	1.2\|285208\|29\|LR134193\|CRISPRCasFinder	285208-285236	29	LR134193.1	1979157-1979185	2	0.931
LR134193_7	7.1\|2675814\|34\|LR134193\|CRISPRCasFinder	2675814-2675847	34	LR134193.1	1009049-1009082	2	0.941

1. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 401320-401347, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

2. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 625103-625130, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

3. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 795039-795066, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

4. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1035071-1035098, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

5. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1325157-1325184, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

6. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1413904-1413931, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

7. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1657236-1657263, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

8. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1871735-1871762, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

9. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1980500-1980527, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

10. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 2333764-2333791, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

11. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 2675774-2675801, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

12. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 285097-285125, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

13. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 804018-804046, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

14. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1009095-1009123, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

15. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 2514020-2514048, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

16. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 2514076-2514104, mismatch: 0, identity: 1.0

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacaataatg	Protospacer
*****************************

17. spacer 4.1|1979060|26|LR134193|CRISPRCasFinder matches to position: 795059-795084, mismatch: 0, identity: 1.0

cgaaattctctgtgttggggcccaca	CRISPR spacer
cgaaattctctgtgttggggcccaca	Protospacer
**************************

18. spacer 4.1|1979060|26|LR134193|CRISPRCasFinder matches to position: 1980520-1980545, mismatch: 0, identity: 1.0

cgaaattctctgtgttggggcccaca	CRISPR spacer
cgaaattctctgtgttggggcccaca	Protospacer
**************************

19. spacer 4.1|1979060|26|LR134193|CRISPRCasFinder matches to position: 2333784-2333809, mismatch: 0, identity: 1.0

cgaaattctctgtgttggggcccaca	CRISPR spacer
cgaaattctctgtgttggggcccaca	Protospacer
**************************

20. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 361227-361254, mismatch: 1, identity: 0.964

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaagcaa	Protospacer
***********************.****

21. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 909337-909364, mismatch: 1, identity: 0.964

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaagcaa	Protospacer
***********************.****

22. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 2182500-2182528, mismatch: 1, identity: 0.966

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcggaaagtcagcttacattaatg	Protospacer
*********************** *****

23. spacer 2.1|625141|28|LR134193|CRISPRCasFinder matches to position: 1979119-1979146, mismatch: 1, identity: 0.964

ggtgtgggccccaacacagagaatttca	CRISPR spacer
ggtgtgggccccaacatagagaatttca	Protospacer
****************.***********

24. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1111327-1111354, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcaaaaagaaattctacagacaa	Protospacer
*******.****************.***

25. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1776729-1776756, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaaacaa	Protospacer
***********************..***

26. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 1989850-1989877, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaggaaattctacagacaa	Protospacer
***********.************.***

27. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 2344572-2344599, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcaaaaagaaattctacagacaa	Protospacer
*******.****************.***

28. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to position: 2792638-2792665, mismatch: 2, identity: 0.929

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaaacaa	Protospacer
***********************..***

29. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 361171-361199, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

30. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 625215-625243, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcgaaaagacagcttacaataatg	Protospacer
********.**** ***************

31. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1035128-1035156, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

32. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1111269-1111297, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

33. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1325215-1325243, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

34. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1413961-1413989, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

35. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1657180-1657208, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

36. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1657293-1657321, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

37. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1671768-1671796, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctggcgaaaagacagcttacaataatg	Protospacer
********.**** ***************

38. spacer 1.2|285208|29|LR134193|CRISPRCasFinder matches to position: 1979157-1979185, mismatch: 2, identity: 0.931

agctggcggaaagtcagcttacaataatg	CRISPR spacer
agctgacgaaaagtcagcttacaataatg	Protospacer
*****.**.********************

39. spacer 7.1|2675814|34|LR134193|CRISPRCasFinder matches to position: 1009049-1009082, mismatch: 2, identity: 0.941

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagaggaattggatttccaat	Protospacer
******************.*********.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

275302 : 317515

Lactococcus_phage(28.57%)

lysis,holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB63820.1\|275302_277057_+\|lysis	Autolysis histidine kinase LytS	Q9EYF3	Enterobacteria_phage	9.0e-63	31.5
VEB63823.1\|277059_277800_+\|lysis	Autolysis response regulater LytR	NA	NA	NA	NA
VEB63825.1\|277918_278356_+\|holin	holin-like protein	NA	NA	NA	NA
VEB63827.1\|278348_279050_+	LrgA-associated membrane protein LrgB	NA	NA	NA	NA
VEB63829.1\|279390_281682_+	nitric oxide reductase	NA	NA	NA	NA
VEB63831.1\|281907_282612_-	Transcriptional regulator, GntR family	NA	NA	NA	NA
VEB63833.1\|282760_283552_+	PTS system, N-acetylglucosamine-specific IIA component / PTS system, N-acetylglucosamine-specific IIB component / PTS system, N-acetylglucosamine-specific IIC component	NA	NA	NA	NA
VEB63835.1\|283567_285004_+	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	6.3e-30	25.8
VEB63838.1\|285498_286260_-	SAM-dependent methyltransferase	NA	NA	NA	NA
VEB63840.1\|286510_287425_-	Ribokinase	NA	NA	NA	NA
VEB63843.1\|287452_287857_-	Ribose ABC transport system, high affinity permease RbsD	NA	NA	NA	NA
VEB63845.1\|287871_288753_-	sugar transport protein	NA	NA	NA	NA
VEB63847.1\|288984_289983_-	ribose operon repressor, putative	NA	NA	NA	NA
VEB63849.1\|290363_290756_+	Uncharacterised protein	NA	NA	NA	NA
VEB63851.1\|290883_292260_-	multidrug resistance protein B	NA	NA	NA	NA
VEB63853.1\|292493_293486_+	choloylglycine hydrolase	NA	NA	NA	NA
VEB63855.1\|293811_294759_+	peptidoglycan hydrolase	V5R8R0	Arthrobacter_phage	2.0e-16	42.7
VEB63857.1\|294810_295470_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.5e-23	32.0
VEB63859.1\|295483_296404_-	ABC-2 family transporter protein	NA	NA	NA	NA
VEB63861.1\|296400_297567_-	ABC-2 transporter family protein	NA	NA	NA	NA
VEB63863.1\|297634_298357_-	Uncharacterised protein	NA	NA	NA	NA
VEB63865.1\|298382_299159_-	Uncharacterised protein	NA	NA	NA	NA
VEB63867.1\|299489_300392_-	staphyloxanthin biosynthesis protein, putative	NA	NA	NA	NA
VEB63868.1\|300630_300924_+	Virulence factor esxA	NA	NA	NA	NA
VEB63870.1\|301006_304036_+	Putative secretion accessory protein EsaA/YueB	NA	NA	NA	NA
VEB63873.1\|304035_304494_+	Putative secretion system component EssA	NA	NA	NA	NA
VEB63875.1\|304465_304708_+	Putative secretion accessory protein EsaB/YukD	NA	NA	NA	NA
VEB63877.1\|304720_306055_+	essB	NA	NA	NA	NA
VEB63879.1\|306076_308548_+	FtsK/SpoIIIE family protein, putative secretion system component EssC/YukA	V5UPA0	Mycobacterium_phage	1.4e-16	32.0
VEB63881.1\|308516_310508_+	DNA translocase FtsK	NA	NA	NA	NA
VEB63883.1\|310520_311600_+	Uncharacterised protein	NA	NA	NA	NA
VEB63885.1\|311602_311797_+	Uncharacterised protein	NA	NA	NA	NA
VEB63887.1\|311906_312617_+\|transposase	Bacillus transposase protein	NA	NA	NA	NA
VEB63889.1\|312576_313170_+	Uncharacterised protein	NA	NA	NA	NA
VEB63891.1\|313182_313596_+	Uncharacterised protein	NA	NA	NA	NA
VEB63893.1\|313606_314080_+	membrane protein	NA	NA	NA	NA
VEB63895.1\|314094_314469_+	Uncharacterised protein	NA	NA	NA	NA
VEB63897.1\|314486_314876_+	Uncharacterised protein	NA	NA	NA	NA
VEB63899.1\|314877_315270_+	Uncharacterised protein	NA	NA	NA	NA
VEB63901.1\|315500_316268_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
VEB63903.1\|316279_317515_-\|transposase	transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1

DBSCAN-SWA_2

727625 : 735446

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB64534.1\|727625_728681_-	Sensor histidine protein kinase SaeS (exoprotein expression protein S)	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
VEB64536.1\|728680_729367_-	Response regulator SaeR	NA	NA	NA	NA
VEB64538.1\|729341_729815_-	DoxX family protein	NA	NA	NA	NA
VEB64539.1\|730157_730598_-	lipoprotein	NA	NA	NA	NA
VEB64541.1\|730877_731462_-	Uncharacterised protein	NA	NA	NA	NA
VEB64543.1\|731560_732274_-	Queuosine Biosynthesis QueE Radical SAM	A0A1U9WRB6	Streptococcus_virus	9.3e-51	42.7
VEB64545.1\|732277_732697_-	6-pyruvoyl-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
VEB64547.1\|732698_733367_-	Queuosine Biosynthesis QueC ATPase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
VEB64549.1\|733717_734311_+	Para-aminobenzoate synthase, amidotransferase component PabAb	A0A0P0IKJ1	Acinetobacter_phage	3.7e-37	42.4
VEB64550.1\|734294_735446_+	Para-aminobenzoate synthetase component I	S4VNU7	Pandoravirus	1.2e-23	36.1

DBSCAN-SWA_3

747419 : 759686

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB64569.1\|747419_748475_+	histidinol-phosphate aminotransferase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.4
VEB64571.1\|748635_749178_+	5'-3'-deoxyribonucleotidase, putative	NA	NA	NA	NA
VEB64573.1\|749570_750488_-	Transcription regulator (contains diacylglycerol kinase catalytic domain)	A0A1V0SBJ0	Catovirus	6.2e-07	22.4
VEB64575.1\|750757_752263_-	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
VEB64578.1\|752600_753101_-	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
VEB64580.1\|753120_753987_-	Integral membrane domain protein	NA	NA	NA	NA
VEB64582.1\|754787_755186_+	Nrdi	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
VEB64584.1\|755148_757254_+	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
VEB64586.1\|757373_758345_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
VEB64588.1\|758386_758569_+	Uncharacterised protein	NA	NA	NA	NA
VEB64590.1\|758714_759686_+	FatD	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2

DBSCAN-SWA_4

810380 : 819954

Lactococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB64678.1\|810380_811685_+	enolase	W6LP63	Streptococcus_phage	6.7e-196	80.7
VEB64680.1\|812035_812494_+	membrane spanning protein	NA	NA	NA	NA
VEB64682.1\|812560_812794_+	protein translocase subunit	NA	NA	NA	NA
VEB64684.1\|812909_813650_+	Carboxylesterase	NA	NA	NA	NA
VEB64686.1\|813683_816056_+	3'-to-5' exoribonuclease RNase R	Q0GXV6	Lactococcus_phage	6.6e-93	39.0
VEB64688.1\|816077_816542_+	tmRNA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
VEB64690.1\|817470_817884_-	putative lipoprotein	H9A0X8	Staphylococcus_phage	1.8e-09	42.0
VEB64692.1\|817939_818707_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
VEB64694.1\|818718_819954_-\|transposase	transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1

DBSCAN-SWA_5

935214 : 979032

Lactococcus_phage(33.33%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB64893.1\|935214_935787_+\|transposase	putative transposase	A0ZS58	Staphylococcus_virus	8.1e-05	100.0
VEB64894.1\|935812_936802_-\|tRNA	Tryptophanyl-tRNA synthetase; proteobacterial type	NA	NA	NA	NA
VEB64895.1\|937096_937492_+	arsenate reductase family protein	NA	NA	NA	NA
VEB64896.1\|937703_938189_+\|transposase	IS605/IS200-like transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
VEB64898.1\|938604_939324_+	Negative regulator of genetic competence MecA	NA	NA	NA	NA
VEB64899.1\|939444_940431_+	Competence protein CoiA	NA	NA	NA	NA
VEB64900.1\|940478_942287_+	Oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
VEB64901.1\|942746_943553_-	putative dithiol-disulfide isomerase	NA	NA	NA	NA
VEB64903.1\|943575_943941_-	bacterial globin-like protein	NA	NA	NA	NA
VEB64904.1\|944044_944638_-	Adenylate cyclase	NA	NA	NA	NA
VEB64906.1\|944823_945171_+	Uncharacterised protein	NA	NA	NA	NA
VEB64907.1\|945187_945823_+	GTP pyrophosphokinase	NA	NA	NA	NA
VEB64909.1\|945839_946649_+	NAD kinase	NA	NA	NA	NA
VEB64911.1\|946645_947500_+	ribosomal large subunit pseudouridine synthase D	NA	NA	NA	NA
VEB64913.1\|947520_948906_+	putative divalent cation transport protein	NA	NA	NA	NA
VEB64915.1\|948915_950760_+	Na+/H+ antiporter-like protein	NA	NA	NA	NA
VEB64917.1\|951037_951808_+	enoyl-ACP reductase	NA	NA	NA	NA
VEB64919.1\|952004_953090_-	membrane protein	NA	NA	NA	NA
VEB64920.1\|953431_955000_+	Sodium/proton-dependent alanine carrier protein	NA	NA	NA	NA
VEB64922.1\|955144_955903_+	Acetyl esterase	NA	NA	NA	NA
VEB64924.1\|956096_956606_+	2-5 RNA ligase	NA	NA	NA	NA
VEB64925.1\|956718_957909_-	glycolipid permease ltaA	NA	NA	NA	NA
VEB64927.1\|957886_959062_-	diglucosyldiacylglycerol synthase (LTA membrane anchor synthesis)	NA	NA	NA	NA
VEB64929.1\|959494_960979_+	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
VEB64931.1\|960968_961220_+	yueH-like family protein	NA	NA	NA	NA
VEB64932.1\|961219_962782_+	Peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
VEB64934.1\|963083_963887_+	Tellurite resistance protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
VEB64935.1\|964120_966430_+\|protease	protease	W5SAB9	Pithovirus	2.8e-11	27.4
VEB64937.1\|966446_967805_+	KtrB	NA	NA	NA	NA
VEB64939.1\|967940_969455_+	2,3-cyclic-nucleotide 2-phosphodiesterase	NA	NA	NA	NA
VEB64941.1\|969943_970513_-	Competence transcription factor	NA	NA	NA	NA
VEB64943.1\|970722_970941_+	Uncharacterized conserved protein	NA	NA	NA	NA
VEB64944.1\|971021_972008_-	Lipoate-protein ligase A	NA	NA	NA	NA
VEB64946.1\|972206_972383_+	putative DUF2187-containing protein	NA	NA	NA	NA
VEB64948.1\|972397_973000_+\|protease	metal-dependent membrane protease	NA	NA	NA	NA
VEB64949.1\|974259_976224_+	membrane spanning protein	NA	NA	NA	NA
VEB64951.1\|976226_976547_+	putative DUF1093-containing protein	NA	NA	NA	NA
VEB64953.1\|976543_976900_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.0e-05	40.3
VEB64955.1\|977017_978253_+\|transposase	transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
VEB64956.1\|978264_979032_+\|transposase	transposase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6

DBSCAN-SWA_6

1010403 : 1018876

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB65009.1\|1010403_1010886_+	AIR carboxylase	A0A2P0VNU7	Tetraselmis_virus	4.0e-21	44.0
VEB65011.1\|1010872_1011997_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
VEB65013.1\|1012000_1012705_+	Phosphoribosylaminoimidazole-succinocarboxamide synthase	M4R1E8	Synechococcus_phage	6.2e-47	41.6
VEB65015.1\|1012704_1012968_+	Phosphoribosylformylglycinamidine synthase, PurS subunit	NA	NA	NA	NA
VEB65017.1\|1012969_1013641_+	Phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
VEB65019.1\|1013633_1015823_+	Phosphoribosylformylglycinamidine synthase, synthetase subunit	A6N228	Microbacterium_phage	4.6e-141	39.8
VEB65020.1\|1015801_1017286_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
VEB65021.1\|1017278_1018307_+	Phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
VEB65022.1\|1018309_1018876_+	Phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.5e-30	40.7

DBSCAN-SWA_7

1219204 : 1329207

106

Staphylococcus_phage(18.75%)

protease,transposase,head,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB65291.1\|1219204_1220491_+\|protease	Membrane-associated zinc metalloprotease	NA	NA	NA	NA
VEB65292.1\|1220510_1222214_+\|tRNA	Prolyl-tRNA synthetase	NA	NA	NA	NA
VEB65293.1\|1222471_1226788_+	DNA polymerase III subunit alpha	A0A0A8WJ41	Clostridium_phage	3.5e-23	41.2
VEB65294.1\|1227075_1227543_+	Putative cytosolic protein	NA	NA	NA	NA
VEB65296.1\|1227563_1228739_+	Transcription termination protein NusA	NA	NA	NA	NA
VEB65297.1\|1228759_1229044_+	nucleic-acid-binding protein implicated in transcription termination	NA	NA	NA	NA
VEB65298.1\|1229040_1229358_+	ribosomal protein L7Ae family protein	NA	NA	NA	NA
VEB65300.1\|1229362_1231480_+	protein translation initiation factor 2 (IF-2)	E3T4N3	Cafeteria_roenbergensis_virus	2.4e-25	25.1
VEB65301.1\|1231865_1232216_+	ribosome-binding factor A	NA	NA	NA	NA
VEB65302.1\|1232384_1233302_+\|tRNA	tRNA pseudouridine synthase B	NA	NA	NA	NA
VEB65303.1\|1233316_1234288_+	Riboflavin kinase / FMN adenylyltransferase	A0A1V0SJE1	Klosneuvirus	1.7e-07	32.1
VEB65305.1\|1234402_1234672_+	30S ribosomal protein S15	NA	NA	NA	NA
VEB65306.1\|1237373_1239047_+	Zn-dependent hydrolase	NA	NA	NA	NA
VEB65307.1\|1239303_1241673_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	1.3e-83	47.5
VEB65308.1\|1241677_1242391_+	GntR family transcriptional regulator	NA	NA	NA	NA
VEB65310.1\|1242421_1243687_+\|protease	Zinc protease	A0A1X9I714	Streptococcus_phage	5.4e-41	26.8
VEB65311.1\|1243686_1244973_+	peptidase, M16 family	G3MBJ8	Bacillus_virus	7.9e-16	28.4
VEB65312.1\|1244972_1245677_+	3-oxoacyl-[acyl-carrier protein] reductase	NA	NA	NA	NA
VEB65313.1\|1245781_1246609_+	protein with ACT domain	NA	NA	NA	NA
VEB65315.1\|1246627_1247020_+	DNA-binding protein	NA	NA	NA	NA
VEB65316.1\|1247053_1247632_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
VEB65317.1\|1247856_1249008_+	Competence/damage-inducible protein CinA	NA	NA	NA	NA
VEB65319.1\|1249172_1250216_+	recombinase A	A0A0S2MVG1	Bacillus_phage	9.3e-124	69.2
VEB65320.1\|1250569_1252129_+	Hydrolase (HAD superfamily)	NA	NA	NA	NA
VEB65321.1\|1252382_1253066_-\|transposase	putative transposase	A0ZS58	Staphylococcus_virus	1.1e-120	93.8
VEB65322.1\|1253115_1253208_-	Transposase	A0A146ICT8	Staphylococcus_phage	1.6e-08	93.1
VEB65324.1\|1253204_1253537_-\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	2.2e-26	92.4
VEB65325.1\|1253873_1254089_-	Uncharacterised protein	NA	NA	NA	NA
VEB65326.1\|1254262_1255060_+	Phosphoesterase family protein	NA	NA	NA	NA
VEB65327.1\|1255199_1256960_+	2-oxoacid ferredoxin oxidoreductase subunit alpha	NA	NA	NA	NA
VEB65328.1\|1256960_1257827_+	2-oxoglutarate oxidoreductase, beta subunit	NA	NA	NA	NA
VEB65330.1\|1257920_1258214_+	Uncharacterized conserved protein	NA	NA	NA	NA
VEB65331.1\|1258347_1259892_+\|tRNA	tRNA-i(6)A37 methylthiotransferase	NA	NA	NA	NA
VEB65332.1\|1259892_1260258_+	membrane protein	NA	NA	NA	NA
VEB65333.1\|1260284_1260776_+	Substrate-specific component ThiWthiazole ECF transporter	NA	NA	NA	NA
VEB65334.1\|1261078_1263697_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	8.5e-41	23.7
VEB65335.1\|1263709_1265719_+	DNA mismatch repair protein MutL	A0A1B2LRQ5	Wolbachia_phage	5.3e-59	29.5
VEB65336.1\|1265733_1266267_+	glycerol uptake operon antiterminator regulatory protein	NA	NA	NA	NA
VEB65337.1\|1266731_1267550_+	Glycerol uptake facilitator protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	2.4e-26	35.1
VEB65338.1\|1267678_1269175_+	glycerol kinase	NA	NA	NA	NA
VEB65339.1\|1269332_1271006_+	Glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
VEB65340.1\|1271152_1272070_+	hydrolase	NA	NA	NA	NA
VEB65341.1\|1272087_1273023_+\|tRNA	tRNA delta(2)-isopentenylpyrophosphate transferase	NA	NA	NA	NA
VEB65342.1\|1273037_1273271_+	RNA-binding protein Hfq	NA	NA	NA	NA
VEB65343.1\|1273492_1273969_-	Glutathione peroxidase family protein	Q70H87	Fowlpox_virus	1.2e-22	38.0
VEB65344.1\|1274080_1275319_+	GTP-binding protein	NA	NA	NA	NA
VEB65345.1\|1275337_1276576_+	aluminum resistance protein, putative	NA	NA	NA	NA
VEB65346.1\|1276819_1277188_+	FemC, factor involved in methicillin resistance / Glutamine synthetase repressor	NA	NA	NA	NA
VEB65348.1\|1277206_1278547_+	glutamine synthetase	NA	NA	NA	NA
VEB65349.1\|1279821_1279911_+	Uncharacterised protein	NA	NA	NA	NA
VEB65350.1\|1279937_1280150_+	Uncharacterised protein	A0A1W6JNK0	Staphylococcus_phage	3.1e-18	71.0
VEB65351.1\|1280443_1280650_+	Uncharacterised protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
VEB65353.1\|1281888_1282074_+	Uncharacterised protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
VEB65354.1\|1282585_1282690_+	Uncharacterised protein	NA	NA	NA	NA
VEB65355.1\|1282818_1283070_+	Uncharacterised protein	NA	NA	NA	NA
VEB65356.1\|1283115_1283403_+\|head	putative phage head morphogenesis protein	A0A1W6JNH6	Staphylococcus_phage	2.5e-18	71.7
VEB65357.1\|1283382_1284150_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
VEB65359.1\|1284161_1285127_-\|transposase	transposase	A0A059NT83	Lactococcus_phage	1.3e-76	51.7
VEB65360.1\|1285083_1285398_-\|transposase	transposase	A0A059NT83	Lactococcus_phage	2.9e-20	45.6
VEB65361.1\|1285531_1285903_+\|head	putative phage head morphogenesis protein	NA	NA	NA	NA
VEB65362.1\|1286023_1286272_+	Uncharacterised protein	NA	NA	NA	NA
VEB65363.1\|1286850_1288116_+	reverse transcriptase	A0A0U4J920	Pseudomonas_phage	2.3e-28	28.7
VEB65365.1\|1288270_1288372_+	Phage protein	NA	NA	NA	NA
VEB65366.1\|1288417_1288684_+\|head	phage head morphogenesis, SPP1 gp7 family domain protein	NA	NA	NA	NA
VEB65367.1\|1288692_1288818_+	Uncharacterised protein	NA	NA	NA	NA
VEB65368.1\|1289245_1289536_+	Uncharacterised protein	S6B1L4	Thermus_phage	5.4e-05	35.1
VEB65370.1\|1289546_1289741_+	Uncharacterised protein	NA	NA	NA	NA
VEB65371.1\|1289781_1290132_+	Uncharacterised protein	NA	NA	NA	NA
VEB65372.1\|1290138_1290330_+	Uncharacterised protein	NA	NA	NA	NA
VEB65373.1\|1290878_1291904_-	Low-specificity L-threonine aldolase	NA	NA	NA	NA
VEB65375.1\|1292173_1292371_+	Uncharacterised protein	NA	NA	NA	NA
VEB65376.1\|1292427_1293909_+	Cardiolipin synthase	NA	NA	NA	NA
VEB65377.1\|1294089_1294989_+	putative antibiotic transport system ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-22	25.9
VEB65378.1\|1294957_1295689_+	ABC transporter permease protein	NA	NA	NA	NA
VEB65380.1\|1295692_1296784_+	Two-component sensor histidine kinase	NA	NA	NA	NA
VEB65381.1\|1296780_1297383_+	DNA-binding response regulator	NA	NA	NA	NA
VEB65382.1\|1297495_1297684_-	membrane protein	NA	NA	NA	NA
VEB65383.1\|1297822_1298356_+	Thermonuclease	A0A1P8CWK6	Bacillus_phage	3.4e-21	43.5
VEB65385.1\|1298498_1299353_-	Uncharacterised protein	NA	NA	NA	NA
VEB65386.1\|1299674_1300259_+	Uncharacterised protein	NA	NA	NA	NA
VEB65387.1\|1300312_1301035_-	aspartate kinase	NA	NA	NA	NA
VEB65388.1\|1301132_1301696_-	aspartate kinase	NA	NA	NA	NA
VEB65389.1\|1301886_1303167_+	Homoserine dehydrogenase	NA	NA	NA	NA
VEB65391.1\|1303172_1304234_+	Threonine synthase	NA	NA	NA	NA
VEB65392.1\|1304235_1305150_+	Homoserine kinase	NA	NA	NA	NA
VEB65394.1\|1305207_1306011_+	Hydrolase (HAD superfamily)	NA	NA	NA	NA
VEB65396.1\|1306339_1306654_-	Uncharacterised protein	NA	NA	NA	NA
VEB65398.1\|1306872_1308327_-	gamma-aminobutyrate permease	NA	NA	NA	NA
VEB65400.1\|1308530_1310048_+	Catalase	A0A2K9L0T1	Tupanvirus	2.3e-91	43.2
VEB65402.1\|1310138_1310288_+	50S ribosomal protein L33	NA	NA	NA	NA
VEB65404.1\|1310741_1311011_+	30S ribosomal protein S14	NA	NA	NA	NA
VEB65405.1\|1311167_1312145_+	putative GMP reductase	Q4ZCY7	Staphylococcus_virus	2.3e-185	99.4
VEB65407.1\|1312319_1313183_+	SCP family extracellular protein	U5Q0C0	Bacillus_phage	4.1e-16	41.5
VEB65408.1\|1313237_1313339_+	Uncharacterised protein	NA	NA	NA	NA
VEB65409.1\|1313561_1314185_-\|protease	SOS-response repressor and protease LexA	A0A1B2APZ1	Phage_Wrath	5.9e-17	63.8
VEB65411.1\|1314324_1314561_+	putative secreted protein	NA	NA	NA	NA
VEB65413.1\|1314696_1314936_+	Putative cytosolic protein	NA	NA	NA	NA
VEB65415.1\|1315056_1317045_+	Transketolase	NA	NA	NA	NA
VEB65417.1\|1317277_1317565_+	Uncharacterised protein family (UPF0154)	NA	NA	NA	NA
VEB65419.1\|1317743_1318211_+	membrane protein	NA	NA	NA	NA
VEB65421.1\|1318334_1319456_+	SbcD protein	A0A1X9I9U0	Staphylococcus_phage	4.3e-10	22.7
VEB65422.1\|1319459_1322489_+	Exonuclease SbcC	NA	NA	NA	NA
VEB65424.1\|1322559_1322922_-	Large-conductance mechanosensitive channel	NA	NA	NA	NA
VEB65427.1\|1323125_1324772_+	Glycine betaine transporter OpuD	A0A2I7QNT1	Vibrio_phage	2.5e-22	24.4
VEB65429.1\|1325606_1328312_+	Aconitate hydratase	NA	NA	NA	NA
VEB65431.1\|1328478_1329207_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	1.7e-23	37.3

DBSCAN-SWA_8

1483233 : 1569168

103

Staphylococcus_phage(78.21%)

tail,head,protease,capsid,transposase,portal,integrase,holin,terminase,tRNA

attL 1493430:1493447|attR 1569723:1569740

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB65672.1\|1483233_1484526_-\|tRNA	asparaginyl-tRNA synthetase	A0A2P1EMB4	Moumouvirus	4.3e-54	30.0
VEB65674.1\|1484824_1487542_-	dinG family ATP-dependent helicase YoaA	A0A1X9I5C8	Streptococcus_phage	3.7e-47	34.4
VEB65676.1\|1487565_1488537_-	Biotin-protein ligase / Biotin operon repressor	NA	NA	NA	NA
VEB65677.1\|1488523_1489726_-	poly A polymerase family protein	H7BUW3	unidentified_phage	1.9e-35	43.3
VEB65679.1\|1489730_1490873_-	glycosyl transferase	NA	NA	NA	NA
VEB65681.1\|1491110_1491428_-	Pyrophosphohydrolase, MazG family	NA	NA	NA	NA
VEB65683.1\|1491764_1492463_-	Neutral zinc metallopeptidase family	NA	NA	NA	NA
VEB65685.1\|1492516_1493104_-	membrane protein	NA	NA	NA	NA
VEB65687.1\|1493093_1493681_-	Putative cytosolic protein	G3MAV7	Bacillus_virus	8.0e-08	26.7
1493430:1493447	attL	NA	NA	NA	NA
VEB65688.1\|1493682_1494927_-	TPR-repeat-containing protein, putative component of Menaquinone-cytochrome C reductase	NA	NA	NA	NA
VEB65689.1\|1494933_1496232_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
VEB65692.1\|1496241_1497306_-	3-dehydroquinate synthase	NA	NA	NA	NA
VEB65694.1\|1497331_1498498_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-34	32.1
VEB65696.1\|1498884_1499085_-	Uncharacterised protein	NA	NA	NA	NA
VEB65697.1\|1499294_1499744_-	Nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
VEB65699.1\|1499835_1500795_-	Farnesyl pyrophosphate synthetase	A0A1V0SE37	Indivirus	1.3e-10	24.4
VEB65701.1\|1500796_1501522_-	Ubiquinone/menaquinone biosynthesis methyltransferase UbiE	NA	NA	NA	NA
VEB65703.1\|1501524_1502097_-	heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein	NA	NA	NA	NA
VEB65705.1\|1502527_1502800_-	DNA-binding protein II HBsu	A7KV42	Bacillus_phage	4.2e-28	73.3
VEB65707.1\|1502970_1503969_-	Glycerol-3-phosphate dehydrogenase (NAD(P)+)	NA	NA	NA	NA
VEB65709.1\|1503985_1505296_-	GTP-binding protein EngA	NA	NA	NA	NA
VEB65711.1\|1505517_1506693_-	30S ribosomal protein S1	NA	NA	NA	NA
VEB65713.1\|1507404_1508064_-	Cytidylate kinase	NA	NA	NA	NA
VEB65715.1\|1508140_1509109_+	L-asparaginase	NA	NA	NA	NA
VEB65716.1\|1509241_1510210_-	thioredoxin reductase	NA	NA	NA	NA
VEB65719.1\|1510612_1512064_-	elastin binding protein ebpS	NA	NA	NA	NA
VEB65721.1\|1512216_1513596_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	6.4e-56	33.3
VEB65723.1\|1513585_1514539_-	Uncharacterised protein	NA	NA	NA	NA
VEB65725.1\|1514646_1514895_+	Ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
VEB65726.1\|1515000_1515546_-	riboflavin transporter	NA	NA	NA	NA
VEB65728.1\|1515947_1516835_-	putative lipoprotein	NA	NA	NA	NA
VEB65730.1\|1517346_1518195_-	Putative cytosolic protein	NA	NA	NA	NA
VEB65732.1\|1518329_1518476_-	Uncharacterised protein	NA	NA	NA	NA
VEB65734.1\|1518459_1519329_-	lipoprotein	NA	NA	NA	NA
VEB65736.1\|1519486_1519834_-	lipoprotein	Q4ZCJ7	Staphylococcus_virus	1.5e-25	98.2
VEB65738.1\|1519880_1520891_-	BcgI-like restriction enzyme subunit beta	A0A1W6JNN3	Staphylococcus_phage	2.7e-64	41.3
VEB65740.1\|1520877_1522782_-	BcgI-like restriction enzyme subunit alpha	A0A1W6JNK1	Staphylococcus_phage	0.0e+00	84.5
VEB65742.1\|1523142_1523898_-	Autolysin	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
VEB65744.1\|1523909_1524164_-\|holin	Phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
VEB65746.1\|1524704_1525004_-	hypothetical phage-related protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
VEB65748.1\|1525049_1525214_-	phage protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
VEB65749.1\|1525206_1525596_-	phage protein	A0A2I6PER1	Staphylococcus_phage	4.9e-62	99.2
VEB65751.1\|1525595_1527062_-\|tail	putative phage tail protein	A0A2I6PES7	Staphylococcus_phage	1.5e-273	100.0
VEB65753.1\|1527061_1528972_-	putative minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
VEB65757.1\|1528987_1529278_-	putative gp53	U5U457	Staphylococcus_phage	2.1e-49	100.0
VEB65759.1\|1529277_1530861_-\|tail	prophage endopeptidase tail family protein	A0A2I6PEQ5	Staphylococcus_phage	3.5e-308	99.8
VEB65761.1\|1530869_1531694_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	7.8e-158	99.6
VEB65763.1\|1531693_1537366_-	phage protein	A0A1X9IGU9	Staphylococcus_phage	0.0e+00	85.5
VEB65765.1\|1537379_1537538_-	putative gp49	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
VEB65767.1\|1537579_1537930_-	putative gp48	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
VEB65769.1\|1537987_1538443_-\|tail	major tail protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
VEB65772.1\|1538534_1539176_-\|tail	major tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
VEB65774.1\|1539210_1539606_-	phage protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
VEB65776.1\|1539606_1540008_-	putative phiSLT protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
VEB65778.1\|1540004_1540337_-	phage protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
VEB65780.1\|1540348_1540627_-\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
VEB65782.1\|1540695_1541859_-\|capsid	putative phage capsid protein	A0A2I6PEQ3	Staphylococcus_phage	2.1e-217	99.7
VEB65784.1\|1541870_1542644_-\|protease	phage protease	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
VEB65786.1\|1542627_1543866_-\|portal	portal protein	A0A2I6PER5	Staphylococcus_phage	6.9e-235	100.0
VEB65788.1\|1543870_1545562_-\|terminase	terminase large subunit	A0A1X9IGU0	Staphylococcus_phage	0.0e+00	99.8
VEB65790.1\|1545551_1545857_-\|terminase	Phage terminase small subunit	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
VEB65792.1\|1545985_1546300_-	HNH endonuclease family protein	A0A2I6PDC4	Staphylococcus_phage	2.5e-56	100.0
VEB65794.1\|1546456_1546894_-	phage regulatory protein	A0A2I6PDC2	Staphylococcus_phage	4.6e-77	100.0
VEB65796.1\|1546906_1548265_-	putative DNA helicase	A0A1X9IH01	Staphylococcus_phage	1.8e-260	99.8
VEB65798.1\|1548254_1548545_-	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
VEB65800.1\|1548885_1551333_-	E family protein	R4WAL1	Staphylococcus_phage	0.0e+00	100.0
VEB65802.1\|1551384_1551585_-	putative exported phage protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
VEB65804.1\|1551652_1551808_-	transcriptional activator rinB-like protein	A7TWI2	Staphylococcus_phage	1.5e-17	94.0
VEB65807.1\|1551804_1552191_-	phage membrane protein	A7TWI1	Staphylococcus_phage	3.4e-63	98.4
VEB65809.1\|1552180_1552417_-	phage protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
VEB65811.1\|1552441_1552678_-	phage protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
VEB65814.1\|1552714_1553242_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	A7TWB1	Staphylococcus_phage	7.8e-95	100.0
VEB65816.1\|1553234_1553483_-	Phage protein	Q9B0F3	Staphylococcus_virus	2.7e-37	97.6
VEB65818.1\|1553497_1553740_-	phage family protein	A0A2D1G5G2	Staphylococcus_phage	2.8e-39	97.5
VEB65820.1\|1553754_1553955_-	phage protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
VEB65821.1\|1553957_1554215_-	phage protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
VEB65823.1\|1554214_1554616_-	putative phi PVL-like protein	A0A2I6PF14	Staphylococcus_phage	3.6e-68	98.5
VEB65825.1\|1554615_1554801_-	phage protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
VEB65827.1\|1554813_1556775_-	DNA polymerase	Q4ZCP5	Staphylococcus_virus	0.0e+00	99.4
VEB65829.1\|1556834_1557389_-	phage protein	M9QRS1	Staphylococcus_phage	1.4e-99	100.0
VEB65831.1\|1557414_1558581_-	PD-(D/E)XK nuclease superfamily protein	R4WAL0	Staphylococcus_phage	7.0e-221	99.7
VEB65833.1\|1558577_1558940_-	phage protein	Q4ZCP8	Staphylococcus_virus	2.2e-56	100.0
VEB65834.1\|1558954_1559278_-	phage protein	A0A2I6PDL5	Staphylococcus_phage	1.3e-52	100.0
VEB65836.1\|1559356_1559518_-	phage protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
VEB65838.1\|1559530_1559794_-	DNA-binding protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
VEB65841.1\|1559818_1560034_-	phage protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
VEB65842.1\|1560088_1560454_+	phage protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
VEB65844.1\|1560422_1560668_-	phage protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
VEB65846.1\|1560734_1561115_+	phage protein	Q4ZCQ5	Staphylococcus_virus	5.8e-68	100.0
VEB65848.1\|1561101_1561299_-	phage protein	A7TWF5	Staphylococcus_phage	4.6e-24	100.0
VEB65851.1\|1561368_1561581_+	putative uracil-DNA glycosylase	D2JGJ1	Staphylococcus_phage	7.6e-33	100.0
VEB65853.1\|1561621_1561771_-	phage protein	D2JGJ0	Staphylococcus_phage	1.4e-20	100.0
VEB65856.1\|1561785_1562229_-	hypothetical phage-related protein	A7TWF2	Staphylococcus_phage	8.9e-76	100.0
VEB65858.1\|1562276_1562489_-	helix-turn-helix family protein	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
VEB65860.1\|1562640_1563372_+	helix-turn-helix family protein	S4SVC5	Staphylococcus_phage	1.3e-132	99.2
VEB65862.1\|1563442_1563625_+	Putative cytosolic protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
VEB65864.1\|1563682_1563808_+	ORF136	A0A2I6PEK8	Staphylococcus_phage	3.3e-12	100.0
VEB65866.1\|1563804_1564419_-	phi PVL ORF 30-like protein	M9QRQ8	Staphylococcus_phage	2.5e-105	99.5
VEB65868.1\|1564544_1565750_+\|integrase	integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
VEB65870.1\|1565792_1566482_-	lipoprotein	B5WZK7	Staphylococcus_phage	1.3e-54	53.7
VEB65872.1\|1566619_1567012_-	lipoprotein	NA	NA	NA	NA
VEB65874.1\|1567153_1567921_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
VEB65876.1\|1567932_1569168_-\|transposase	transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
1569723:1569740	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1628779 : 1637109

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB66005.1\|1628779_1629565_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
VEB66007.1\|1629690_1630581_-	endonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
VEB66009.1\|1630590_1631937_-	ATP-dependent RNA helicase YqfR	A0A1V0SIR5	Klosneuvirus	9.1e-55	33.7
VEB66011.1\|1632050_1633151_-	NIF3 protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
VEB66013.1\|1633153_1633831_-\|tRNA	Putative tRNA-m1A22 methylase	NA	NA	NA	NA
VEB66015.1\|1633961_1635068_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
VEB66017.1\|1635291_1637109_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3

DBSCAN-SWA_10

1706555 : 1715598

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB66154.1\|1706555_1707074_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
VEB66156.1\|1707095_1709369_-	Single-stranded-DNA-specific exonuclease recJ	A7KV88	Bacillus_phage	3.1e-63	29.0
VEB66158.1\|1709571_1711851_-	Protein-export membrane protein secD / Protein-export membrane protein secF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
VEB66160.1\|1712125_1712386_-	Preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
VEB66161.1\|1712404_1713544_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
VEB66163.1\|1713566_1714592_-\|tRNA	S-adenosylmethionine--tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
VEB66165.1\|1714593_1715598_-	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_11

1829507 : 1944514

112

Staphylococcus_phage(74.58%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB66336.1\|1829507_1830152_-\|tRNA	tRNA (guanine46-N7-)-methyltransferase	NA	NA	NA	NA
VEB66337.1\|1830166_1830958_-	phosphotransferase enzyme family	NA	NA	NA	NA
VEB66338.1\|1831508_1832357_-	D-alanine aminotransferase	NA	NA	NA	NA
VEB66340.1\|1832360_1833770_-	Xaa-His dipeptidase	NA	NA	NA	NA
VEB66341.1\|1833972_1834395_-	putative staphylococcal protein	NA	NA	NA	NA
VEB66342.1\|1834411_1835107_-	16S pseudouridine synthase A	NA	NA	NA	NA
VEB66344.1\|1835103_1836765_-	spore cortex protein; Membrane protein involved in the export of O-antigen, teichoic acid lipoteichoic acids	NA	NA	NA	NA
VEB66345.1\|1837170_1838439_+	NAD(FAD)-utilizing dehydrogenase	A0A2H4PQX1	Staphylococcus_phage	9.1e-57	99.1
VEB66346.1\|1838555_1845125_-	putative surface anchored protein	A0A2H4PQU6	Staphylococcus_phage	1.9e-294	92.6
VEB66348.1\|1845450_1845762_-	Rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
VEB66349.1\|1845783_1848201_-\|tRNA	Leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
VEB66350.1\|1848488_1849670_-	Multidrug resistance protein	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
VEB66352.1\|1849780_1850734_+	Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
VEB66353.1\|1850730_1851294_+	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	2.2e-103	100.0
VEB66354.1\|1851413_1851815_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
VEB66356.1\|1852251_1853049_-\|transposase	transposase	A0ZS58	Staphylococcus_virus	1.1e-108	89.5
VEB66357.1\|1853394_1854222_-	Lysophospholipase; Monoglyceride lipase; putative	NA	NA	NA	NA
VEB66359.1\|1854455_1855457_+	Proline dehydrogenase (Proline oxidase)	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
VEB66360.1\|1855578_1856043_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
VEB66361.1\|1856055_1857237_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
VEB66363.1\|1857247_1857880_-	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
VEB66364.1\|1857886_1858930_-	5-amino-6-(5-phosphoribosylamino)uracil reductase	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
VEB66365.1\|1859410_1860913_-	pyridine nucleotide-disulfide oxidoreductase family protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
VEB66366.1\|1861439_1861754_+	arsenical resistance operon repressor 2	A0A2H4PQT4	Staphylococcus_phage	1.3e-52	98.1
VEB66368.1\|1861753_1863046_+	arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	7.5e-216	94.2
VEB66369.1\|1863063_1863459_+	arsenate reductase, putative	A0A2H4PQT9	Staphylococcus_phage	4.5e-71	96.9
VEB66370.1\|1864088_1865231_-	quinolone resistance protein NorA	NA	NA	NA	NA
VEB66372.1\|1865622_1866087_-	ftsk/spoiiie family protein	NA	NA	NA	NA
VEB66373.1\|1866722_1867577_-	peptidoglycan endo-beta-N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
VEB66374.1\|1867852_1868077_-	putative staphylococcal protein	NA	NA	NA	NA
VEB66375.1\|1868275_1868746_+	DNA-binding protein	A0A2H4PQT5	Staphylococcus_phage	1.8e-66	83.9
VEB66377.1\|1868858_1869302_+	comK family protein	NA	NA	NA	NA
VEB66378.1\|1869288_1869732_-	membrane protein	A0A2H4PQT8	Staphylococcus_phage	1.9e-49	77.2
VEB66380.1\|1870029_1870665_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
VEB66381.1\|1870831_1871452_+	membrane protein	NA	NA	NA	NA
VEB66382.1\|1871848_1872562_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
VEB66384.1\|1872820_1873123_+	membrane protein	NA	NA	NA	NA
VEB66385.1\|1873378_1873744_+	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	4.8e-59	99.2
VEB66386.1\|1873740_1874094_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.9e-20	82.9
VEB66388.1\|1874936_1875305_+\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	1.2e-33	94.9
VEB66389.1\|1875301_1875394_+	Transposase	A0A146ICT8	Staphylococcus_phage	1.6e-08	93.1
VEB66390.1\|1875443_1875740_+\|transposase	transposase (fragment)	A0A146ICT8	Staphylococcus_phage	4.1e-53	100.0
VEB66392.1\|1875815_1876127_+\|transposase	putative transposase	Q9MBP7	Staphylococcus_prophage	1.4e-48	94.2
VEB66393.1\|1876189_1877023_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	6.0e-158	99.3
VEB66394.1\|1877239_1878148_-	Uncharacterised protein	A0A2H4PQQ8	Staphylococcus_phage	2.9e-137	98.7
VEB66396.1\|1878272_1879466_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	2.2e-217	99.5
VEB66397.1\|1879836_1881429_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
VEB66398.1\|1881806_1882577_-	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	8.0e-141	97.6
VEB66399.1\|1882557_1883037_-	phosphohydrolase	A0A2H4PQM4	Staphylococcus_phage	1.1e-84	98.7
VEB66401.1\|1883096_1883354_+	Putative cytosolic protein	A0A2H4PQM5	Staphylococcus_phage	2.0e-40	90.6
VEB66402.1\|1883350_1884352_-	O-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
VEB66403.1\|1884356_1885835_-	O-succinylbenzoic acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.6e-283	97.6
VEB66404.1\|1885993_1886476_-	putative lipoprotein	A0A2H4PQN7	Staphylococcus_phage	3.8e-80	99.3
VEB66406.1\|1887178_1887400_+	excalibur domain protein	A0A2H4PQM8	Staphylococcus_phage	7.2e-18	100.0
VEB66407.1\|1887480_1888476_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	1.9e-70	95.2
VEB66408.1\|1888551_1889178_+	lipoprotein	A0A2H4PQM7	Staphylococcus_phage	6.4e-88	91.8
VEB66409.1\|1889218_1889560_+	Uncharacterised protein	A0A2H4PQN6	Staphylococcus_phage	2.5e-54	92.9
VEB66411.1\|1889660_1890281_+	Uncharacterised protein	A0A2H4PQN4	Staphylococcus_phage	2.4e-18	89.8
VEB66412.1\|1890260_1891028_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
VEB66414.1\|1891039_1892275_-\|transposase	transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
VEB66415.1\|1892632_1893202_-	Domain of uncharacterised function (DUF955)	A0A2H4PQN8	Staphylococcus_phage	1.2e-77	95.0
VEB66416.1\|1893574_1893751_-	Uncharacterised protein	NA	NA	NA	NA
VEB66418.1\|1893761_1894145_-	Uncharacterised protein	NA	NA	NA	NA
VEB66419.1\|1894724_1894829_-\|transposase	putative transposase	A0A2H4PQU1	Staphylococcus_phage	7.2e-05	87.5
VEB66420.1\|1895636_1896014_-	exported protein	NA	NA	NA	NA
VEB66421.1\|1896220_1896661_-	putative protein with DUF1433	NA	NA	NA	NA
VEB66423.1\|1896705_1898319_+	pathogenicity island protein	NA	NA	NA	NA
VEB66424.1\|1898333_1898633_+	ESAT-6 family protein	NA	NA	NA	NA
VEB66425.1\|1898949_1900131_-	Uncharacterised protein	NA	NA	NA	NA
VEB66427.1\|1900123_1900978_-	SMF family protein	NA	NA	NA	NA
VEB66428.1\|1901207_1901678_-	Type I restriction-modification system,specificity subunit S	NA	NA	NA	NA
VEB66429.1\|1901802_1902084_+\|transposase	transposase	A0A0C5AJ30	Paenibacillus_phage	6.5e-24	64.5
VEB66430.1\|1902125_1902932_+\|transposase	transposase	A0A2I7SC85	Paenibacillus_phage	1.1e-76	54.9
VEB66431.1\|1903033_1903609_+	Domain of uncharacterised function DUF1829	NA	NA	NA	NA
VEB66433.1\|1904160_1904937_-	extracellular enterotoxin type G precursor	NA	NA	NA	NA
VEB66434.1\|1905219_1905975_-	enterotoxin SeN	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4
VEB66435.1\|1906013_1906784_-	enterotoxin Seu	A0A097PAT7	Streptococcus_pyogenes_phage	6.3e-45	43.6
VEB66436.1\|1906937_1907666_-	extracellular enterotoxin type I precursor	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
VEB66438.1\|1907700_1908420_-	enterotoxin SEM	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
VEB66439.1\|1908700_1909465_-	enterotoxin SeO	A0A1X9H080	Staphylococcus_phage	2.3e-31	37.1
VEB66440.1\|1910830_1911385_-	Putative hydrolase ydeN	NA	NA	NA	NA
VEB66442.1\|1911707_1913108_-	Protoporphyrinogen IX oxidase, aerobic	NA	NA	NA	NA
VEB66443.1\|1913131_1914055_-	Ferrochelatase, protoheme ferro-lyase	NA	NA	NA	NA
VEB66444.1\|1914112_1915150_-	Uroporphyrinogen III decarboxylase	NA	NA	NA	NA
VEB66445.1\|1915411_1915915_+	signal transduction protein	NA	NA	NA	NA
VEB66447.1\|1916038_1917262_-	EcsB	NA	NA	NA	NA
VEB66448.1\|1917254_1917995_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8
VEB66449.1\|1918128_1918551_+	adenosine 5'-monophosphoramidase	NA	NA	NA	NA
VEB66450.1\|1918692_1919058_+	gas vesicle protein-protein	NA	NA	NA	NA
VEB66452.1\|1919790_1920348_+	membrane protein	NA	NA	NA	NA
VEB66453.1\|1920552_1921515_+	Foldase protein PrsA precursor	NA	NA	NA	NA
VEB66454.1\|1921635_1922577_-	CMP-binding-factor 1	NA	NA	NA	NA
VEB66456.1\|1922573_1925510_-	membrane associated protein	NA	NA	NA	NA
VEB66457.1\|1925499_1926696_-	DNA repair exonuclease family protein YhaO	NA	NA	NA	NA
VEB66458.1\|1927467_1927812_-	putative transcriptional regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
VEB66459.1\|1927880_1929005_-	membrane protein	NA	NA	NA	NA
VEB66460.1\|1929183_1929648_-	HTH domain protein, binds to mecA promoter region	NA	NA	NA	NA
VEB66462.1\|1930003_1930627_-	Two-component response regulator-like protein	NA	NA	NA	NA
VEB66463.1\|1930648_1931761_-	Two-component sensor protein	NA	NA	NA	NA
VEB66464.1\|1931923_1932745_+	ribosomal large subunit pseudouridine synthase D	NA	NA	NA	NA
VEB66465.1\|1933206_1934592_-	Fumarate hydratase class II	NA	NA	NA	NA
VEB66467.1\|1934787_1935183_-	membrane protein	NA	NA	NA	NA
VEB66468.1\|1936017_1936170_-	putative staphylococcal protein	NA	NA	NA	NA
VEB66469.1\|1936194_1936794_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
VEB66471.1\|1936952_1937423_-\|tRNA	tRNA (cytosine34-2-O-)-methyltransferase	NA	NA	NA	NA
VEB66472.1\|1937427_1938555_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
VEB66473.1\|1938704_1939433_-	Glutamine transport ATP-binding protein glnQ	G9BWD6	Planktothrix_phage	1.0e-36	42.7
VEB66474.1\|1939419_1940877_-	extracellular glutamine-binding protein	NA	NA	NA	NA
VEB66476.1\|1941135_1942197_-	Regulatory protein	NA	NA	NA	NA
VEB66477.1\|1942952_1943234_+\|transposase	transposase	A0A0C5AJ30	Paenibacillus_phage	6.5e-24	64.5
VEB66478.1\|1943275_1944082_+\|transposase	transposase	A0A2I7SC85	Paenibacillus_phage	1.1e-76	54.9
VEB66479.1\|1944061_1944514_-\|transposase	transposase	A0A1P8BMC0	Lactococcus_phage	2.7e-19	35.4

DBSCAN-SWA_12

1990502 : 2090640

119

Staphylococcus_phage(83.72%)

tail,head,protease,capsid,transposase,holin,terminase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB66529.1\|1990502_1991930_-\|tRNA	aspartyl/glutamyl-tRNA amidotransferase subunit B	NA	NA	NA	NA
VEB66531.1\|1991942_1993400_-\|tRNA	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A	NA	NA	NA	NA
VEB66532.1\|1993401_1993704_-\|tRNA	Aspartyl-tRNA(Asn) amidotransferase subunit C; Glutamyl-tRNA(Gln) amidotransferase subunit C	NA	NA	NA	NA
VEB66533.1\|1994069_1995608_+	Sodium/proline symporter	NA	NA	NA	NA
VEB66534.1\|1995696_1996896_-	Lipoprotein (pheromone precursor)	NA	NA	NA	NA
VEB66536.1\|1996908_1998912_-	DNA ligase	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
VEB66537.1\|1998915_2001108_-	ATP-dependent DNA helicase UvrD/PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
VEB66538.1\|2001104_2001797_-	geranylgeranylglyceryl diphosphate synthase	NA	NA	NA	NA
VEB66540.1\|2001968_2002271_-	His repressor	NA	NA	NA	NA
VEB66541.1\|2002379_2003675_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
VEB66542.1\|2004534_2005701_+	Staphopain A precursor	NA	NA	NA	NA
VEB66544.1\|2005731_2006058_+\|protease	putative cysteine protease inhibitor (Staphostatin A)	NA	NA	NA	NA
VEB66545.1\|2006644_2006962_+\|transposase	truncated transposase for IS1272	A0A146ICT8	Staphylococcus_phage	3.5e-50	100.0
VEB66546.1\|2007118_2007463_+\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	1.1e-54	95.6
VEB66548.1\|2007605_2007779_-	Uncharacterised protein	NA	NA	NA	NA
VEB66549.1\|2007759_2008362_-	Uncharacterized protein conserved in bacteria (DUF2179)	NA	NA	NA	NA
VEB66551.1\|2008632_2009454_-	NH(3)-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	7.9e-70	53.1
VEB66552.1\|2009446_2010916_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.5e-108	45.1
VEB66553.1\|2011099_2012176_+	nitric-oxide synthase	NA	NA	NA	NA
VEB66554.1\|2012195_2012990_+	ACT domain protein	NA	NA	NA	NA
VEB66555.1\|2013179_2014742_-	sodium-dependent dicarboxylate transporter sdcS	NA	NA	NA	NA
VEB66557.1\|2014946_2016044_-	cell wall surface anchor family protein	U5PWM6	Bacillus_phage	1.6e-46	34.3
VEB66559.1\|2016415_2016976_+	Nicotinamidase	G3MA16	Bacillus_virus	2.0e-32	41.2
VEB66560.1\|2017028_2017958_+	inorganic pyrophosphatase	NA	NA	NA	NA
VEB66561.1\|2018377_2019757_+	Aldehyde dehydrogenase	NA	NA	NA	NA
VEB66562.1\|2019876_2020905_-	6-phosphogluconolactonase	NA	NA	NA	NA
VEB66563.1\|2021363_2021744_-	penicillinase repressor	NA	NA	NA	NA
VEB66565.1\|2021733_2023491_-	Beta-lactamase regulator protein	NA	NA	NA	NA
VEB66566.1\|2023597_2024443_+	beta-lactamase	A0A1B0VBP7	Salmonella_phage	3.4e-31	34.3
VEB66567.1\|2024756_2025167_+	YolD-like protein	U3PG23	Staphylococcus_phage	1.4e-30	54.2
VEB66569.1\|2025195_2025561_-	Transposase FOR transposon Tn554	NA	NA	NA	NA
VEB66571.1\|2025569_2027633_-\|transposase	transposase B regulatory protein	NA	NA	NA	NA
VEB66572.1\|2027635_2028787_-	Transposase	P97010	Streptococcus_pyogenes_phage	9.0e-11	31.0
VEB66573.1\|2029293_2029467_-	exported protein	NA	NA	NA	NA
VEB66575.1\|2029845_2030958_+	choloylglycine hydrolase	NA	NA	NA	NA
VEB66576.1\|2031014_2031857_-	exported protein	NA	NA	NA	NA
VEB66577.1\|2031853_2032411_-	Predicted membrane protein	NA	NA	NA	NA
VEB66578.1\|2032470_2032995_-	membrane protein	NA	NA	NA	NA
VEB66580.1\|2033115_2033679_+	Thioredoxin	NA	NA	NA	NA
VEB66581.1\|2033744_2034485_-	ABC-2 transporter family protein	NA	NA	NA	NA
VEB66582.1\|2034484_2035357_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
VEB66584.1\|2035353_2036034_-	membrane protein	NA	NA	NA	NA
VEB66585.1\|2036034_2036931_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.5e-17	30.2
VEB66586.1\|2036927_2037308_-	GntR family transcriptional regulator	NA	NA	NA	NA
VEB66587.1\|2037584_2037743_-	membrane protein	NA	NA	NA	NA
VEB66589.1\|2038283_2039570_+	Aspartate aminotransferase	NA	NA	NA	NA
VEB66590.1\|2039848_2041897_-	MHC class II analog (pseudogene)	NA	NA	NA	NA
VEB66591.1\|2042282_2042483_+	beta-hemolysin	A0A1P8L6A7	Staphylococcus_phage	1.0e-26	98.5
VEB66593.1\|2043657_2044008_-	Involved in expression of fibrinogen binding protein, phage associated	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
VEB66594.1\|2044692_2045142_+	Chemotaxis-inhibiting protein CHIPS, phage associated	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
VEB66595.1\|2045236_2045533_-	amidase	A0A1P8L6B4	Staphylococcus_phage	1.3e-51	100.0
VEB66597.1\|2046221_2046713_-	Staphylokinase	A0A1X9H028	Staphylococcus_phage	1.2e-86	99.4
VEB66598.1\|2046903_2047659_-	Autolysin	D2JLG5	Staphylococcus_phage	2.2e-151	99.6
VEB66599.1\|2047670_2047925_-\|holin	Phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
VEB66601.1\|2048462_2048693_-	phage protein	D2JLG2	Staphylococcus_phage	1.2e-31	100.0
VEB66602.1\|2048816_2049104_-	phage protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
VEB66603.1\|2049150_2049303_-	phage protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
VEB66605.1\|2049292_2053078_-	phage minor structural protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.4
VEB66606.1\|2053093_2054578_-	bacteriophage protein	A0A068A242	Staphylococcus_phage	2.0e-297	99.8
VEB66607.1\|2054574_2057436_-\|tail	TP901 family phage tail tape measure protein	A0EX03	Staphylococcus_phage	0.0e+00	98.6
VEB66608.1\|2057488_2059105_-\|tail	Phage tail length tape-measure protein	A0A1W6JPL0	Staphylococcus_phage	1.1e-251	99.1
VEB66610.1\|2059161_2059299_-	phage protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
VEB66611.1\|2059349_2059700_-	phage protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
VEB66612.1\|2060016_2060658_-\|tail	phage major tail protein	A0A1W6JPP5	Staphylococcus_phage	1.1e-119	100.0
VEB66613.1\|2060658_2061066_-	putative bacteriophage protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
VEB66615.1\|2061298_2061466_-	phage protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-15	100.0
VEB66616.1\|2061462_2061825_-\|head,tail	phage head-tail adaptor	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
VEB66617.1\|2061808_2062093_-	Gp6 protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
VEB66619.1\|2062082_2062367_-\|terminase	phage terminase small subunit	A0A1W6JPL8	Staphylococcus_phage	2.3e-45	100.0
VEB66620.1\|2062386_2063607_-\|capsid	Phage major capsid protein	A0A075LYD8	Staphylococcus_phage	7.8e-231	100.0
VEB66621.1\|2063554_2064292_-	ATP-dependent endopeptidase clp proteolytic subunit	A0A1W6JPK0	Staphylococcus_phage	1.8e-129	100.0
VEB66622.1\|2064275_2065439_-	Portal protein, phage associated	A0A1W6JPQ9	Staphylococcus_phage	1.8e-216	100.0
VEB66624.1\|2065454_2067116_-\|terminase	Phage terminase large subunit	Q8LTH3	Staphylococcus_phage	0.0e+00	99.8
VEB66625.1\|2067112_2067457_-	phage protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
VEB66626.1\|2067587_2067887_-	phage-associated homing endonuclease	A0A1W6JPL7	Staphylococcus_phage	2.7e-52	100.0
VEB66627.1\|2068118_2068535_-	phage transcriptional regulator	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
VEB66629.1\|2068562_2068763_-	phage protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
VEB66630.1\|2068762_2068912_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
VEB66631.1\|2068908_2069298_-	phage membrane protein	A0A1W6JPK8	Staphylococcus_phage	8.9e-64	100.0
VEB66632.1\|2069287_2069524_-	phage protein	A0A2I6PDD1	Staphylococcus_phage	4.8e-36	98.7
VEB66634.1\|2069516_2069804_-	phage protein	Q4ZAB6	Staphylococcus_virus	2.4e-45	98.9
VEB66635.1\|2069840_2070374_-	dUTP pyrophosphatase	A0A059T5A7	Staphylococcus_phage	2.1e-92	97.2
VEB66636.1\|2070366_2070537_-	phage protein	A7TWH6	Staphylococcus_phage	2.2e-22	94.6
VEB66638.1\|2070523_2070778_-	Phage protein	A0A2I6PDI5	Staphylococcus_phage	2.1e-37	96.4
VEB66639.1\|2070770_2071055_-	phage protein	E9LT36	Staphylococcus_phage	2.7e-46	100.0
VEB66640.1\|2071232_2071514_+\|transposase	transposase	A0A0C5AJ30	Paenibacillus_phage	6.5e-24	64.5
VEB66642.1\|2071555_2072362_+\|transposase	transposase	A0A2I7SC85	Paenibacillus_phage	1.1e-76	54.9
VEB66643.1\|2072358_2072727_-	YopX-family protein	A0A2I6PDH2	Staphylococcus_phage	1.1e-60	100.0
VEB66645.1\|2072723_2072918_-	phage protein	A0A2I6PE33	Staphylococcus_phage	2.5e-27	100.0
VEB66646.1\|2072914_2073301_-	phage protein	I1W655	Staphylococcus_phage	4.1e-69	100.0
VEB66647.1\|2073314_2073557_-	phage family protein	R9QT89	Staphylococcus_phage	3.0e-41	100.0
VEB66649.1\|2073560_2073929_-	Phage protein	A0A0E3XD52	Staphylococcus_phage	6.7e-53	100.0
VEB66650.1\|2073941_2074346_-	phage protein	A0A0E3XBN4	Staphylococcus_phage	4.2e-72	99.3
VEB66651.1\|2074354_2074573_-	phage protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
VEB66652.1\|2074579_2075464_-	Phage protein	S4V6D4	Staphylococcus_phage	3.1e-136	95.6
VEB66654.1\|2075493_2075964_-	Single-stranded DNA-binding protein, phage associated	A0A1P8L6D9	Staphylococcus_phage	9.7e-81	99.4
VEB66655.1\|2075964_2076450_-	Metallo-beta-lactamase superfamily domain protein in prophage	A0A2I6PDI9	Staphylococcus_phage	2.7e-86	99.4
VEB66656.1\|2076662_2077583_-	recombinase, phage RecT family protein	A0A1V0E5D7	Staphylococcus_phage	1.0e-166	100.0
VEB66658.1\|2077584_2079528_-	Uncharacterized conserved protein	I1W619	Staphylococcus_phage	0.0e+00	100.0
VEB66659.1\|2079536_2079800_-	phage protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
VEB66660.1\|2079808_2080069_-	putative phi PVL-like protein	A0A2I6PDH1	Staphylococcus_phage	2.6e-43	100.0
VEB66661.1\|2080162_2080324_-	phage protein	Q4ZAZ7	Staphylococcus_virus	2.5e-20	100.0
VEB66663.1\|2080320_2080641_-	Uncharacterized protein conserved in bacteria	A0A1W6JPI1	Staphylococcus_phage	7.4e-56	100.0
VEB66664.1\|2080873_2081134_-	putative phi PVL-like protein	A0A2I6PDT7	Staphylococcus_phage	3.5e-40	100.0
VEB66665.1\|2081146_2081896_-	putative phage anti-repressor protein	A0A1W6JPN2	Staphylococcus_phage	2.0e-136	100.0
VEB66666.1\|2081952_2082162_+	Uncharacterised protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
VEB66667.1\|2082154_2082295_-	phage protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
VEB66669.1\|2082309_2082756_-	phage protein	A0A1W6JPI3	Staphylococcus_phage	1.9e-78	100.0
VEB66670.1\|2082768_2083011_-	phage DNA-binding protein	A0A1X9H035	Staphylococcus_phage	1.6e-39	100.0
VEB66671.1\|2083174_2083891_+	putative phage repressor protein	A0A1X9H038	Staphylococcus_phage	1.2e-130	99.6
VEB66673.1\|2083902_2084757_+	HIRAN domain-containing protein	A0A1X9H037	Staphylococcus_phage	7.3e-151	100.0
VEB66674.1\|2084830_2084977_+	phage protein	A0A1X9H032	Staphylococcus_phage	3.3e-19	100.0
VEB66675.1\|2084973_2085159_+	phage protein	U5U7D6	Staphylococcus_phage	2.3e-25	100.0
VEB66677.1\|2085229_2085412_+	Putative cytosolic protein	A0A2I6PDR4	Staphylococcus_phage	3.4e-26	98.3
VEB66678.1\|2085489_2086203_+	phi77 ORF017-like protein	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
VEB66679.1\|2086393_2087431_+	DNA integration/recombination/inversion protein	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
VEB66680.1\|2087487_2088312_+	phospholipase C	A0A1P8L6H7	Staphylococcus_phage	6.8e-162	100.0
VEB66682.1\|2088549_2089566_-	gamma-hemolysin component B	A0A2I6PER8	Staphylococcus_phage	3.9e-26	29.3
VEB66683.1\|2089587_2090640_-	Leukocidin S subunit	A0A2I6PDF3	Staphylococcus_phage	1.3e-35	32.1

DBSCAN-SWA_13

2098101 : 2137317

Staphylococcus_phage(21.43%)

protease,terminase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB66692.1\|2098101_2098692_-\|terminase	putative phage terminase	Q4ZE85	Staphylococcus_phage	1.2e-96	94.7
VEB66693.1\|2098688_2098901_-\|transposase	transposase	Q4ZE86	Staphylococcus_phage	1.1e-23	74.3
VEB66694.1\|2099602_2101219_-	heat shock protein 60 family chaperone GroEL	A0A240F779	uncultured_virus	5.8e-157	54.7
VEB66695.1\|2101294_2101579_-	Heat shock protein 60 family co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
VEB66697.1\|2101755_2102499_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
VEB66698.1\|2102522_2103782_-	membrane anchored protein	NA	NA	NA	NA
VEB66699.1\|2103978_2104605_+	nitroreductase family protein	NA	NA	NA	NA
VEB66700.1\|2104874_2105660_+	Aliphatic amidase amiE	NA	NA	NA	NA
VEB66702.1\|2106574_2107198_+	accessory gene regulator protein B AGRB	NA	NA	NA	NA
VEB66703.1\|2107194_2107335_+	Regulator protein agrD	NA	NA	NA	NA
VEB66704.1\|2107359_2108652_+	Regulator protein agrC	NA	NA	NA	NA
VEB66705.1\|2108670_2109387_+	accessory gene regulator protein A	A0A2H4J4Z6	uncultured_Caudovirales_phage	2.3e-25	32.6
VEB66707.1\|2109754_2110714_-	Fructokinase	NA	NA	NA	NA
VEB66708.1\|2110710_2112195_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	8.0e-20	25.8
VEB66709.1\|2112343_2113294_-	Sucrose operon repressor ScrR, LacI family	NA	NA	NA	NA
VEB66710.1\|2113476_2114727_-	ammonium transporter family protein	H8ZJB2	Ostreococcus_tauri_virus	1.0e-39	31.0
VEB66712.1\|2114934_2115159_-	transcriptional regulator	NA	NA	NA	NA
VEB66713.1\|2115223_2116297_-	putative transport system permease protein	NA	NA	NA	NA
VEB66714.1\|2116600_2117236_-	Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	NA	NA	NA	NA
VEB66715.1\|2117488_2119417_+	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	1.2e-52	30.7
VEB66717.1\|2120001_2120298_+\|transposase	transposase for IS1272	A0A146ICT8	Staphylococcus_phage	7.5e-47	97.9
VEB66718.1\|2120312_2121923_+	MutS-related protein, family 1	A0A0N9R0S5	Chrysochromulina_ericina_virus	3.3e-19	26.9
VEB66719.1\|2122024_2123050_-\|protease	glycoprotease	A0A0R6PI74	Moraxella_phage	5.3e-63	40.9
VEB66720.1\|2123042_2123507_-	Ribosomal-protein-S18p-alanine acetyltransferase	NA	NA	NA	NA
VEB66722.1\|2123479_2124142_-\|protease	Inactive protein of metal-dependent protease family, putative molecular chaperone	NA	NA	NA	NA
VEB66723.1\|2124122_2124617_-	ATP/GTP hydrolase	NA	NA	NA	NA
VEB66724.1\|2125094_2126783_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
VEB66726.1\|2126810_2128580_+	acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	2.0e-62	29.9
VEB66727.1\|2128579_2128834_+	Acetolactate synthase small subunit	NA	NA	NA	NA
VEB66728.1\|2128971_2129976_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
VEB66729.1\|2130005_2131535_+	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	3.2e-08	28.1
VEB66731.1\|2131537_2132584_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
VEB66732.1\|2132597_2133968_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
VEB66733.1\|2133968_2134541_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
VEB66734.1\|2134555_2135824_+	Threonine dehydratase	NA	NA	NA	NA
VEB66735.1\|2136024_2137317_+\|transposase	transposase, putative	A0A2L1IVA1	Escherichia_phage	3.9e-15	31.2

DBSCAN-SWA_14

2509406 : 2564052

Bacillus_phage(30.0%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB67953.1\|2509406_2509763_-\|transposase	transposase for IS1272	A0A146ICT8	Staphylococcus_phage	7.7e-62	99.2
VEB67961.1\|2510170_2511904_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.4e-31	25.9
VEB67965.1\|2511928_2513692_-	ABC transporter ATPase/permease	W8CYL7	Bacillus_phage	4.2e-36	24.7
VEB67970.1\|2514692_2515079_-	Putative sugar translocase in surface polysaccharides biosynthesis	NA	NA	NA	NA
VEB67974.1\|2515346_2516489_+	glycerate kinase	W6LM47	Streptococcus_phage	5.3e-56	44.3
VEB67978.1\|2516548_2517208_+	Uncharacterised protein	NA	NA	NA	NA
VEB67982.1\|2517386_2518598_+	Bicyclomycin resistance protein TcaB	NA	NA	NA	NA
VEB67986.1\|2518720_2519194_-	Putative transcriptional activator	NA	NA	NA	NA
VEB67992.1\|2519306_2519963_+	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEB67996.1\|2520025_2520832_-	putative phosphoesterase, putative	NA	NA	NA	NA
VEB68000.1\|2521117_2522527_+	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
VEB68004.1\|2522664_2524743_+	Na+/H+ antiporter	NA	NA	NA	NA
VEB68008.1\|2524882_2526712_-	Amino acid permease	NA	NA	NA	NA
VEB68010.1\|2526943_2528440_+	flp protein	NA	NA	NA	NA
VEB68014.1\|2528530_2529382_-	putative NAD-dependent epimerase/dehydratase	NA	NA	NA	NA
VEB68017.1\|2529705_2530641_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
VEB68020.1\|2530866_2532267_-	integral membrane efflux protein	NA	NA	NA	NA
VEB68023.1\|2532560_2533256_-\|holin	putative glycine betaine/carnitine/choline transport system permease protein	NA	NA	NA	NA
VEB68026.1\|2533255_2534197_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, substrate-binding protein OpuCC	NA	NA	NA	NA
VEB68029.1\|2534213_2534849_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCB	NA	NA	NA	NA
VEB68033.1\|2534845_2536072_-\|holin	glycine betaine/carnitine/choline ABC transporter, ATP-binding protein, putative	Q6GZ03	Mycoplasma_phage	6.6e-20	50.5
VEB68036.1\|2536741_2537341_-	molecular chaperone GroEL	NA	NA	NA	NA
VEB68038.1\|2537521_2539159_+	Amino acid permease	NA	NA	NA	NA
VEB68041.1\|2539465_2540818_+	Carboxylesterase type B	A0A0B5J865	Pandoravirus	8.6e-13	34.2
VEB68044.1\|2540879_2542067_-	chloramphenicol resistance protein	NA	NA	NA	NA
VEB68047.1\|2542460_2543237_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
VEB68050.1\|2543229_2543892_-	ABC superfamily ATP binding cassette transporter, ABC protein	W8CYL7	Bacillus_phage	4.8e-17	33.9
VEB68053.1\|2544237_2545314_-	endoglucanase M	NA	NA	NA	NA
VEB68056.1\|2545668_2545935_-	addiction module toxin	NA	NA	NA	NA
VEB68059.1\|2545934_2546192_-	prevent-host-death family protein	NA	NA	NA	NA
VEB68062.1\|2546550_2547006_+	lipoprotein	NA	NA	NA	NA
VEB68065.1\|2547173_2548751_-	Ferredoxin-dependent glutamate synthase	NA	NA	NA	NA
VEB68069.1\|2548945_2549695_+	membrane protein	NA	NA	NA	NA
VEB68072.1\|2550160_2551354_-	Antibiotic resistance protein	NA	NA	NA	NA
VEB68075.1\|2551365_2552115_-	nickel transport ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-20	31.2
VEB68078.1\|2552107_2552923_-	Oligopeptide transporter putative ATPase domain protein	G9BWD6	Planktothrix_phage	3.6e-14	30.3
VEB68081.1\|2552919_2553789_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
VEB68084.1\|2553785_2554721_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
VEB68088.1\|2554733_2556332_-	Oligopeptide transporter putative substrate binding domain protein	NA	NA	NA	NA
VEB68091.1\|2556474_2557776_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEB68095.1\|2557768_2558587_-	nicotianamine synthase	NA	NA	NA	NA
VEB68098.1\|2558597_2559419_-	Putative Similar to diaminopimelate epimerase	NA	NA	NA	NA
VEB68101.1\|2560297_2560663_-	Uncharacterised protein	NA	NA	NA	NA
VEB68103.1\|2560926_2561745_-	Glutamate dehydrogenase	L7RG25	Acanthamoeba_polyphaga_moumouvirus	1.7e-08	26.5
VEB68105.1\|2561979_2563518_+	aminobenzoyl-glutamate transport protein	NA	NA	NA	NA
VEB68107.1\|2563629_2564052_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_15

2628797 : 2636904

Staphylococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEB68325.1\|2628797_2629766_-	Esterase/lipase	A0A167RJ59	Powai_lake_megavirus	6.8e-12	26.1
VEB68329.1\|2629886_2630243_-	thioredoxin	NA	NA	NA	NA
VEB68333.1\|2630284_2630695_-	thioesterase superfamily protein	NA	NA	NA	NA
VEB68337.1\|2631230_2631494_+\|transposase	transposase for IS1272	A0A146ICT8	Staphylococcus_phage	2.2e-42	97.7
VEB68341.1\|2632047_2632233_+\|transposase	putative transposase	A0A146ICT8	Staphylococcus_phage	8.1e-15	92.9
VEB68345.1\|2632337_2632682_+\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	2.0e-51	92.1
VEB68349.1\|2632797_2634897_-	Pts system, glucose-specific iiabc component	A0A2I7SAJ6	Vibrio_phage	8.4e-07	43.3
VEB68353.1\|2635164_2636904_-	Pyruvate oxidase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.0e-34	24.1

Anti-CRISPR protein detection

Acr_ID: LR134193.1|VEB66374.1|1867852_1868077_-|putative-staphylococcal-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LR134193.1|VEB66374.1|1867852_1868077_-|putative-staphylococcal-protein

1867852_1868077_-

74 aa aa

LuxR_C_like

Identity	Hit_domain_coverage
0.42857142857142855	0.7368421052631579

1829507-1944514

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
LR134193_1	Orphan	1.1\|285153\|28\|LR134193\|CRISPRCasFinder	285153-285180	28	1871735-1871762	0

1. spacer 1.1|285153|28|LR134193|CRISPRCasFinder matches to LR134193 position: 1871735-1871762, mismatch: 0

gaatttcgaaaagaaattctacaggcaa	CRISPR spacer
gaatttcgaaaagaaattctacaggcaa	Protospacer
****************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134193

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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