CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134242	Staphylococcus epidermidis strain NCTC4133 genome assembly, chromosome: 1	2 crisprs	cas1,cas2,WYL,csa3,DEDDh,cas3,DinG	0	7	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134242_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134242_1

102352-102913

TypeII

Consensus_repeat	Method
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	PILER-CR
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CRISPRCasFinder
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CRT

8 spacers

cas9,cas1,cas2

The CRISPR arrays of LR134242_1

>merge|LR134242|1|102352-102913|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACAAACCATGTATCCCTCGTTAGTTTTTAGATGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACGTGCAATTTTAGGTGTTCTTGCTACGTTAGGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACTGTAGGTATCTTTGTAAGTTGTAATTAACGTTTTAGTACTCTGTAATTTTAGATATGAGTGAAACCGGTTGATTTAACAGTTAGAGCTTTTATTAGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACTTTTTAAATTTGTGATACCGATGTTTTGTGGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACAAACTGATTTAGCAGTGTTTAATGGTGGTTGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACTTTCATTAGCTTATCTATCAGATATTTTAAGTTTTAGTACTCTGTAATTTTAGGTATAAGTGAAACGGTGTTTTTAACAAGTCTAATCCGTATGCGTTTTAGTACTTTGTAATTTGAATATTGAAAGTATA

>LR134242|1|1|102352-102848|PILER-CR
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	AAACCATGTATCCCTCGTTAGTTTTTAGAT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	GTGCAATTTTAGGTGTTCTTGCTACGTTAG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TGTAGGTATCTTTGTAAGTTGTAATTAAC
GTTTTAGTACTCTGTAATTTTAGATATGAGTGAAAC	CGGTTGATTTAACAGTTAGAGCTTTTATTA
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTTTAAATTTGTGATACCGATGTTTTGTG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	AAACTGATTTAGCAGTGTTTAATGGTGGTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTCATTAGCTTATCTATCAGATATTTTAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGAAAC

>LR134242|1|1|102352-102913|CRISPRCasFinder
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	AAACCATGTATCCCTCGTTAGTTTTTAGAT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	GTGCAATTTTAGGTGTTCTTGCTACGTTAG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TGTAGGTATCTTTGTAAGTTGTAATTAAC
GTTTTAGTACTCTGTAATTTTAGATATGAGTGAAAC	CGGTTGATTTAACAGTTAGAGCTTTTATTA
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTTTAAATTTGTGATACCGATGTTTTGTG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	AAACTGATTTAGCAGTGTTTAATGGTGGTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTCATTAGCTTATCTATCAGATATTTTAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGAAAC	GGTGTTTTTAACAAGTCTAATCCGTATGC
GTTTTAGTACTTTGTAATTTGAATATTGAAAGTATA

>LR134242|1|1|102352-102913|CRT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	AAACCATGTATCCCTCGTTAGTTTTTAGAT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	GTGCAATTTTAGGTGTTCTTGCTACGTTAG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TGTAGGTATCTTTGTAAGTTGTAATTAAC
GTTTTAGTACTCTGTAATTTTAGATATGAGTGAAAC	CGGTTGATTTAACAGTTAGAGCTTTTATTA
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTTTAAATTTGTGATACCGATGTTTTGTG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	AAACTGATTTAGCAGTGTTTAATGGTGGTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTCATTAGCTTATCTATCAGATATTTTAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGAAAC	GGTGTTTTTAACAAGTCTAATCCGTATGC
GTTTTAGTACTTTGTAATTTGAATATTGAAAGTATA

Protein	Signature genes	Signature genes Name	Protein_function
LR134242.1\|VED25510.1\|101256_102195_+\|putative-dioxygenase	unknown	unknown	gnl\|CDD\|319935
LR134242.1\|VED25522.1\|110702_111041_+\|MazG-like-family	unknown	unknown	gnl\|CDD\|212144
LR134242.1\|VED25500.1\|96132_97068_+\|oligopeptide-transporter-putative-membrane-permease	unknown	unknown	gnl\|CDD\|223674
LR134242.1\|VED25512.1\|103164_106329_+\|CRISPR-associated-protein,-Csn1-family	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
LR134242.1\|VED25502.1\|97064_97934_+\|peptide-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|131837
LR134242.1\|VED25508.1\|99499_100678_+\|transporter	unknown	unknown	gnl\|CDD\|341042
LR134242.1\|VED25506.1\|98738_99488_+\|oligopeptide-transporter-putative-ATPase-domain-protein	unknown	unknown	gnl\|CDD\|224049
LR134242.1\|VED25528.1\|115068_116004_+\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
LR134242.1\|VED25514.1\|106331_107234_+\|CRISPR-associated-protein-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
LR134242.1\|VED25516.1\|107238_107547_+\|CRISPR-associated-protein-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LR134242.1\|VED25498.1\|94521_96120_+\|oligopeptide-transporter-putative-substrate-binding-domain-protein	unknown	unknown	gnl\|CDD\|274072
LR134242.1\|VED25496.1\|93161_94454_+\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|370816
LR134242.1\|VED25520.1\|108963_110697_+\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|378274
LR134242.1\|VED25492.1\|91514_92354_+\|Putative-Similar-to-diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|223331
LR134242.1\|VED25504.1\|97930_98746_+\|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein	unknown	unknown	gnl\|CDD\|223521
LR134242.1\|VED25524.1\|111159_113019_+\|Activator-of-the-mannose-operon-(transcriptional-antiterminator),-BglG-family	unknown	unknown	gnl\|CDD\|226234
LR134242.1\|VED25518.1\|107560_108568_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134242.1\|VED25530.1\|116254_117091_+\|putative-lipoprotein	unknown	unknown	gnl\|CDD\|235040
LR134242.1\|VED25494.1\|92353_93169_+\|nicotianamine-synthase	unknown	unknown	gnl\|CDD\|176222
LR134242.1\|VED25526.1\|113098_115054_+\|putative-fructose-phosphotransferase-system-enzyme-fruA	unknown	unknown	gnl\|CDD\|224218

Protein	Function_ID	Function_description	E-value
LR134242.1\|VED25510.1\|101256_102195_+\|putative-dioxygenase	gnl\|CDD\|319935	cd08347, PcpA_C_like, C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The C-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	7.96148e-41
LR134242.1\|VED25522.1\|110702_111041_+\|MazG-like-family	gnl\|CDD\|212144	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs. RS21-C6 proteins, highly expressed in all vertebrate genomes and green plants, act as house-cleaning enzymes, removing 5-methyl dCTP (m5dCTP) in order to prevent gene silencing. They show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, RS21-C6 contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. Divalent ions, such as Mg2+, are required for its pyrophosphatase activity. This family also includes a pyrophosphatase from Archaeoglobus fulgidus (Af1178). Although its biological role remains unclear, Af1178 shows significant sequence similarity to the mouse RS21-C6 protein.	4.56263e-36
LR134242.1\|VED25500.1\|96132_97068_+\|oligopeptide-transporter-putative-membrane-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.57629e-97
LR134242.1\|VED25512.1\|103164_106329_+\|CRISPR-associated-protein,-Csn1-family	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	1.20067e-112
LR134242.1\|VED25502.1\|97064_97934_+\|peptide-ABC-transporter-permease	gnl\|CDD\|131837	TIGR02790, Nickel_transport_system_permease_protein_nikC., nickel ABC transporter, permease subunit NikC. This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds].	4.02182e-83
LR134242.1\|VED25508.1\|99499_100678_+\|transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.29023e-68
LR134242.1\|VED25506.1\|98738_99488_+\|oligopeptide-transporter-putative-ATPase-domain-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.14345e-99
LR134242.1\|VED25528.1\|115068_116004_+\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	1.95336e-127
LR134242.1\|VED25514.1\|106331_107234_+\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	8.75615e-98
LR134242.1\|VED25516.1\|107238_107547_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.07146e-32
LR134242.1\|VED25498.1\|94521_96120_+\|oligopeptide-transporter-putative-substrate-binding-domain-protein	gnl\|CDD\|274072	TIGR02294, Nickel-binding_periplasmic_protein, nickel ABC transporter, nickel/metallophore periplasmic binding protein. Members of this family are periplasmic nickel-binding proteins of nickel ABC transporters. Most appear to be lipoproteins. This protein was previously (circa 2003) thought to mediate binding to nickel through water molecules, but is now thought to involve a chelating organic molecule, perhaps butane-1,2,4-tricarboxylate, acting as a metallophore. [Transport and binding proteins, Cations and iron carrying compounds].	0
LR134242.1\|VED25496.1\|93161_94454_+\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|370816	pfam10100, DUF2338, Uncharacterized protein conserved in bacteria (DUF2338). Members of this family of hypothetical bacterial proteins have no known function.	0
LR134242.1\|VED25520.1\|108963_110697_+\|Uncharacterized-conserved-protein	gnl\|CDD\|378274	pfam09848, DUF2075, Uncharacterized conserved protein (DUF2075). This domain, found in various prokaryotic proteins (including putative ATP/GTP binding proteins), has no known function.	1.87642e-100
LR134242.1\|VED25492.1\|91514_92354_+\|Putative-Similar-to-diaminopimelate-epimerase	gnl\|CDD\|223331	COG0253, DapF, Diaminopimelate epimerase [Amino acid transport and metabolism].	2.94595e-44
LR134242.1\|VED25504.1\|97930_98746_+\|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.64867e-112
LR134242.1\|VED25524.1\|111159_113019_+\|Activator-of-the-mannose-operon-(transcriptional-antiterminator),-BglG-family	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.1389e-32
LR134242.1\|VED25530.1\|116254_117091_+\|putative-lipoprotein	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	3.72427e-59
LR134242.1\|VED25494.1\|92353_93169_+\|nicotianamine-synthase	gnl\|CDD\|176222	cd08261, Zn_ADH7, Alcohol dehydrogenases of the MDR family. This group contains members identified as related to zinc-dependent alcohol dehydrogenase and other members of the MDR family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group includes various activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.30073e-05
LR134242.1\|VED25526.1\|113098_115054_+\|putative-fructose-phosphotransferase-system-enzyme-fruA	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	4.39486e-148

>LR134242.1|VED25510.1|101256_102195_+|putative-dioxygenase
MTIVGHHHISMYTKDAVKNKAFYTELLGLRLVEKTVNQDNTKMYHLFYGDNAGHPGTLLTFFEIENVGKHRPGTDSIHRLTLLVPSETALDYFKQRLDQNNVEWTSLLYLDQSAVLLKDPDELEIILLVNDDYQTPEQWSANDDTVIPKDVQILGMGPVELRSRKPEALTEFLEHILGYHQRNDLEADDNTTIMTLDEQGLYTDFVIVNQQGHRVRPGQGYVHHVAVNLPTDTDLNDIYEKIARQPNPNSGIIDRYFFKSLYYRHNQILFEFATAEPGFTVDTPVAKLGQQLNLPDFLEDKRDEIESQLREI
>LR134242.1|VED25508.1|99499_100678_+|transporter
MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTTIGIVMGVYMLTAMVFRPWAGQIIARVGPIKVLRIILLINACALILYGLTGLEGYFIARVMQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLVGPLIAVGIWHLDRISIFAIVMIAIALTTTFFGYRVTFASEEPDTRKKVEPLPFNAVTVFAQFFKNKELFNSGLIMIVVSIVFGAVSTFVPLYTVKFGFADAGILLTIQAIAVVLARIYLRKYIPSDGIWHPVYMVSVLMLLVIASMLVAIGPHIHVLIFYSSAILIGATQALVYPTLTSYLSFVLPKAGRNMLLGLFIACADLGVSLGGSLMGPISDLVGFSWMYTICGMLVVVMMLMSAFKGIRQK
>LR134242.1|VED25506.1|98738_99488_+|oligopeptide-transporter-putative-ATPase-domain-protein
MIKINHVEKHYGKRSLWGPKPKPIIKDVSLDCPVDEAIAIIGESGSGKSTLSRMILGIERPDKGTVTLNDQPMYKKKVRRHQIGAVFQDYTSSLHPFQTVRDILFEVMCQCDKQSTDEMEGAAKTLLEEVGLSEDFLDKYPNMLSGGEAQRVAIARAICINPTYILFDEAISALDMSIQTQILDLLKRLKHTRHLSYIFITHDIQAATYLCDRLVIFKDGQIEEQIATRDLHTTTNAYTQALIDKQLSF
>LR134242.1|VED25504.1|97930_98746_+|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein
MTLLTVQQLTIRDEWTDTTLVDDINFQVKRGETLGIIGESGSGKSITCKALVELNPSRLKVTGKVHFDGHNLLALSERQLRQYRGQAIAMVMQQGARAFDPSTKVGKQMIETMQVHTSLSTQEVEQTLIDYMTYMNLTDPQNILASYPYMLSGGMLQRLMIALALALKPKLIIADEPTTALDTINQFDVLEAFEDIKQHFDCAMIFISHDLAVIHKVADRVIVMKEGQLVEEGTTEAVLHHPHHRYTQYLLSTKQKVNDHFQRVMRGDSHD
>LR134242.1|VED25502.1|97064_97934_+|peptide-ABC-transporter-permease
MMIVKRLLQDRGAVVALVIIATYFLLGFLAPVITFHEPNHIDTAHKFAGISATHWLGTDHLGRDVLTRLIYAIRPSLLYVSIALVISVAIGAILGFISGYFRGYIDALIMRCCDVMLAFPSYVVTLALITLFGMGVENIILAFILTRWAWFCRVIRTSVMQYTSADHVKFAKTIGMSDFTIIRKHILPLTLGDIAIISSSAMCSMILQMSGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPGMMVTTGIVIVIIVMAFNFLSDALQVAMDPRISSKEKMRAVKKGVMHE
>LR134242.1|VED25500.1|96132_97068_+|oligopeptide-transporter-putative-membrane-permease
MFKLIIKRIALMFPLLIVVSFMTFMMTYLTNEDPAVTILHAQGTPNVTPQLIAETKEKYGLDAPILVQYKDWLQQAVQFKFGTSYITGDPVSERIGPAFMNTLKLTLISSVSVMVTSICLGVVSALTRGQRTDRVIRSVAFFLTALPSYWVASMLIIYVSVKLNLLPTSGLTGPESYVLPVVVITMSYAGIYFRNVRRAMIEQLNEDYVLYLKASGVKTMTLLRHVLRNALQVAVSIFCMSIPMIMGGLVVIENVFAWPGLGQLSIKAIVEHDFPVVQTYVLIVAVLFIIFNTLADIINALLNPRLREASR
>LR134242.1|VED25498.1|94521_96120_+|oligopeptide-transporter-putative-substrate-binding-domain-protein
MNKLTKMSAVLLASGIILTGCGGNKGLEDKKEQKTLSYTTVKDIGDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWDISKDGKTYTFHLRDDVKFHDGTKFNAEAVKKNIDAVQQNKKLHSWLKISTLIDDVKVKDDYTVQIHLKEAYQPALAELAMPRPYVFVSPKDFKHGTTKDGVKAFNGTGPFKMGEHKKDESATFNKNQHYWGERAKLNKVEAKVKPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKETGDYNVKRSQPMNTKMIVANAGNKDSAVSDKSIRQAIGHMVDRDKIAKDILDGQEKPATQLFAKNVTDINFNMPTRQFDTKKAEKLLDQAGWKMKQDKQIRQKDGKDLTMTMYYDKGSTSQKEQAEFLEAEFKKVGVKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKSKTGYESATSGIKDKKKLYNDIDEAFKMKDEKERSKAYQQILKQVDDEGVFIPISHGSMTVVAPKDLKNVSFTQSQYELPFNEMQYK
>LR134242.1|VED25496.1|93161_94454_+|Uncharacterized-protein-conserved-in-bacteria
MSNILIIGSGPVAIQLAQLCNRVSKNHIDMVGRASTTKKSLDVYQSYQQAGTFTVTTQNDTHHQFAGQFQIRHFYQDIQQIDESYDTIILACTADAYRPMLQQLALTILQHVKHIILVSPTFGSHMMIEQLLADINTDVEVISFSTYLGDTRVVDMAQPHRVLTMAVKSKLFVGSNKPSSQLIPQLQTWFESLHIQLAVMDTPLHAEIHNSSLYVHPPLFMNDFALKAIFEGIDVPVYVYKLFPEGPITMILIREMRQIWQEMMTILQKLSVPSVNLLKFMVKENYPVRSETISESDIHQFEELPAIHQEYLLYVRYTAILIDPFSKPDKDGRYFDFSAVPFKSLYQNEQGVVHIPRMPSEDYYRTTVIQAIGKALGVSTPMIDTLLHRYVGYCERYQIEHPQQSVSSQFNLDDFEEDISLVTTYLANKS
>LR134242.1|VED25494.1|92353_93169_+|nicotianamine-synthase
MHSNTKIETLLQQYLEQFEARYQHVLSDPNSIDALESLVDDYSQLILNPTYQQQYDLWQDEPRKQLITQQLQDITAQCVKQVEMIRARRLLDGKASTSGYFDNIEHCIDEEFGQCHIGKEDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGQRVVNVLAPNEDIHISNQTVDQLSDIKEVTHIIFSSTIPVKYEILAQLFELTNDRVVVAMRYGDGMKAIFNYPSQPTASDQWQCVHHLVQPNQIFDVALYQKALSQAGITYV
>LR134242.1|VED25492.1|91514_92354_+|Putative-Similar-to-diaminopimelate-epimerase
MNRQVIEFSKYNPSGNMTILVHSQHHPNDYAKIANQLMASTHVCCEQVGFIESNNLNHGDDCRLVMSGNEFCGNATMSYMHYLQEHQRLTAQQCHLNVSGCDDLVHCTIHGHQQYEVGMPQARYVTTEYLHIAQHMWQAIKITYESYVHYVIPIEEITATFKQQVAQFVREQQWDEQYKTIGIMLFNVQDQYLHPLIYIPEVKSLIWENSCGSGAASIGVFNNYQSQQSCEDYIVYQPGGSISVTSAYCSEDGYRTSIKGRVSTVARGQAYIEEETMTH
>LR134242.1|VED25512.1|103164_106329_+|CRISPR-associated-protein,-Csn1-family
MKEKYILGLDLGITSVGYGIINFETKKIIDAGVRLFPEANVDNNEGRRSKRGSRRLKRRRIHRLDRVKSLLTEYNLINREQIPTSNNPYQIRVKGLSEILSKDELAIALLHLAKRRGIHNINVSSEDEDASNELSTKEQINRNNKLLKNKYVCEVQLQRLKEGQIRGEKNRFKTTDILKEIDQLLKVQKDYHNLDIDFINQYKEIVETRREYFEGPGQGSPFGWNGDLKKWYEMLMGHCTYFPQELRSVKYAYSADLFNALNDLNNLIIQRNDSEKLEYHEKYHIIENVFKQKKKPTLKQIAKEIGVNPEDIKGYRITKSGTPQFTEFKLYHDLKSIVFDKSILENEAILDQIAEILTIYQDEESIKEELNKLPEILNEQDKAEIAKLTGYNGTHRLSLKCIHLINEELWQTSRNQMEIFNYLNIKPNKVDLSEQNKIPKDLVDEFILSPVVKRTFIQSINVINKVIEKYGIPEDIIIELARENNSDDRKKFINNLQKKNEATRKRINEIIGQTGNQNAKRIVEKIRLHDQQEGKCLYSLESIPLMDLLNNPQNYEVDHIIPRSVAFDNSIHNKVLVKQIENSKKGNRTPYQYLNSSDANLSYNQFKQHILNLSKSKDRISKKKKDYLLEERDINKFEVQKEFINRNLVDTRYATRELTSYLKAYFSANNMDVKVKTINGSFTNHLRKVWRFDKYRNHGYKHHAEDALIIANADFLFKENKKLQNANKILEKPTIENDTQKVTVEKEEDYNNMFETPKLVEDIKQYRDYKFSHRVDKKPNRQLIKDTLYSTRMKDEHNYIVQTITDIYGKDNTNLKKQFNKNPEKFLMYQNDPKTFEKLSIIMKQYSDEKNPLAKYYEETGEYLTKYSKKNNGPIVKKIKLLGNKVGNHLDVTNKYENSTKKLVKLSIKNYRFDVYLTEKGYKFVTIAYLNVFKKDNYYYIPKDLYQELKAKKKIKDTDQFIASFYKNDLIKLNGDLYKIIGVNSDDRNIIELDYYDIKYKDYCEINNIKGEPRIKKTIGKKTESIEKLTTDVLGNLYLHTTEKAPQLIFKRGL
>LR134242.1|VED25514.1|106331_107234_+|CRISPR-associated-protein-Cas1
MSWRIVYVSDVNHMSLNLNSLKIMKGDLETKIPLSDIFALVIEDLTTTITARLLVELSDYNILVIFCNQKHLPECTLQPVSGHFNQYTQMKEQLKWDEARKSELWKIIIENKIQNQIECMKYLSIQSDRVDKMIELKNSVTLFDRNNIEGQAAKYYFNSFFEDFTRDNEEIIENAVLNYGYTILNSAIARTIVAKGLIPAIGIHHIGGRNHFNLASDLIEPFRPIVDLFLLKHPPQDFLTKEYRVKIINLLHARIEIDGKMQTVIRAIEIMIQSIIDYFKDGQLDRVKFPKLSKYSFYEL
>LR134242.1|VED25516.1|107238_107547_+|CRISPR-associated-protein-Cas2
MRVLLMFDLPTETKKHRRIYSKFRKNLIEDGFLMMQYSIYIKSVVNKDAANQTIKRVNTFLPSEGHVRALIITEKQYEHMQILLGEENQNIEILGDNRTIIF
>LR134242.1|VED25518.1|107560_108568_+|Uncharacterised-protein
MTNLQWCIKTDSLPTITLNIGKYTAIYNEYETIEEDLLNVINQYFKKRNSNKSNVTIAEMLNQEEISPLSYESIIIDNRAIDNEFLLSSNSIINKKLQRDFYENIESNSYIESINVLFEDLLNLINKAELPLKSKTFDIKQFIKLLSFEYSLNEDYSKLIVRIEQILPLLVEELNKQYGGKLLLIYLYPEANLSPKEQIRLKELIISLGIDIIVLTGSLHFLAEDWKYNNYIRCDNQKISSELVDNLLWNAPLNFERSEIEQSLNQFILAYQDKIEIKPIISNYQIAQIMLFSSIDLYVGVSYMQHCNHEFILNIDETKLPLSMAKYLEQFVKEN
>LR134242.1|VED25520.1|108963_110697_+|Uncharacterized-conserved-protein
MSSMRKPIIKNISYSNEELVNSLGEWQQSDDSKFLLRYPTVYIINDKNKSDHFNLYVGETTDIKNRTIQHLKNDVKLKDYWKSFYSSDTSSMYVIGHPFFNKSLTLDIENKFMQYLSSVDAVNSIFNSRTNQQNEYYTSEKLDEIFTNIWQQLHKENSKLFPIESVIKDSAIFKASPFHKLTNEQQSVKDEILNKIEHAILSESEENQLILVEGEAGSGKTVLMSTLFFELKQMMDLDEMKNLDIHLLVNHDQQLKVYKQIANKLGLEGKNQNIINKPTSFILNRDVEDKADVVIIDEAHLLLTQGKMSYRGEGHLKDIQKRAKVVVAVFDKKQILSKQQIWEFDTLDKLIQYSKDQNNHLLLKNQLRINSSIETMNWLRHLIDDHKIDPIPHDSKGYDIKIFDTPAELEKAILRKTKNIESGLSRMLATFDWEFKNGKSPNDGLFWEVKIGQWSRPWNLQLKCPRGEKNLAWPEQSQTINEIGSTFTIQGFDLNYAGVIIGPSVKFRNGKIIYDKSESKNIQVTQNRKLSDDTMKNFGEELLRNELNVLLTRGVNGLYIYAVDDELRNALKEASKG
>LR134242.1|VED25522.1|110702_111041_+|MazG-like-family
MRTENSVMEKINQFRDERNWRQFHNEKDLALSITLEASELLELFQWKSSEDVVESKRERLAEELADILIYSYMFADNLDFDINEIIEQKLVKNAEKYPVDKSKDNNSKYNEL
>LR134242.1|VED25524.1|111159_113019_+|Activator-of-the-mannose-operon-(transcriptional-antiterminator),-BglG-family
MIERQIKLIELLRNNRSDYLKSDDIAAYLNISNRTARTDIKIINNQFMPEVIGNIKSKGYFLNTTRYSLEDIDNQLSNYLNQDGKLLIKIAYQLLMYSTSVLISELMEQFQLSKKEILDYMSRIQMWCEKYEVNIIIKRKTGITVTGNEKDINNAILHLNQLSKQHHRVEDLILNELPKAHIQMIKQIIEDNLSVHDIRTSHLQIEQLVIHLILILKRQSISEESWNINDESLVISNEIIKDINQRLGYHLNTQTVQLFSFFISYHFNKFDLGFEKVFIESYIQQLITKMEQKMHLKFGSDNVLKDNLLAHFSRTYLRIMKEVYLNNPLTGEIKILYPYVFNVLYDIIHELAKDTGINLSEDEIAFLTIHFQASIDRNEVSQVNIAICCYYGLGISQLLETKISKVNQHVKVTDILRFEDIENDAFENIDILITTHDIHMQLPQDLDVIKVSPLFSEDDQFKLNRIVKGKLNPIAKNNELNEIPVTIVNNDFIQTIPGVFETAHQILNNYKAISSGYIETALNREKASSTYIGNSMTMPHGDPTKVLSSNIIIFKSNNGFYWKEHKIKLVFFLAIAKPDIHLMKQMMQNLSLLDEEDIHQLAHLEETTFQNKILKLIKG
>LR134242.1|VED25526.1|113098_115054_+|putative-fructose-phosphotransferase-system-enzyme-fruA
MKILAITSCPNGIAHTYMAQEKLEQAAKKMGVDIKVETQGGVGAENVLTTKEIREADGIIIAADRQVDLSRFNGKRLINENVREGIHHPETLIQRIIDQDAKIYHDKNATTQSNDSDDEEDRKSGIQMVYQHLMNGVSFMVPFIVVGGLLIAIALTLGGHPTSEGLKIPDDSFWKSIENIGKLSFGFMVPILAGYIAYSIADKPGLVPGMIGGAIAADGSLYGSEAGAGFLGGIVAGFIAGYVAKWIKNIRVPKAMAPIMPIIIIPILASLIVGLIFIFLIGAPISGIFTALTGWLKGMQGANIIILALIIGAMIAFDMGGPVNKVAFLFGSALIAEGNYAVMGMVAVAVCTPPIGLGLATFVQKHKFNHAEQEMGKASFTMGLFGITEGAIPFAAQDPLRIIPSNMIGAMVAAVIAAMGGVGDRVAHGGPIVAVLGGIDHIIWFFIAVIIGSLVTMITILILKRNTPVTDVEEDQEDTHLERSTNSSQGSKYSESKVDESVKHDDNVFQKDVININTNVKTKEEAIDYMVKNLKEHRFIDNEDVVKQAILDREAESTTAIGMNVAIPHAKSDAVNQPTVAVLQNKEGIDWISLDESLPKILFMIVVPNDSNNTHLKLLQRLSRSLMDDKTREALINAPSKDDIYDILKEI
>LR134242.1|VED25528.1|115068_116004_+|mannose-6-phosphate-isomerase
MALFLKPVFQEKIWGGTALESFNYHLPSNNVGECWAISAHPNGPNVIENGHYKGKTLDEVWSIDRSLFGNDKRDKFPLLTKILDANDKLSVQVHPDDDYAQKYEGEYGKTECWYILDAKEDAEIIYGINVDNKEDLVECINNREFDRLFKKVKVKPGDFYYVPAGTVHAIGSGILILETQQSSDTTYRIYDYDRKDKHGHLRDLHLEQSKAVININQENPNVVPQQSEVQGQTVTQFVSNEFFTVEKWRINGKLNYKKPHAYCLVSVIDGTGSVIIDDERHDIQKGRHFIITNEDQNILFDGKLEIIISYS
>LR134242.1|VED25530.1|116254_117091_+|putative-lipoprotein
MKLKYVILVLLAPVFLSACNYSKPENRNGFFYNTFAKPMDLFLNWMGEHLNHNYGLAIIIIVLAIRLIMLPFMLSQTKNGQFMRKLMKIAKPELDPIQEKVRRARTQEEKMDANKEMMDVYKKYHINPMKSMLGCLPMLIQMPILFGLYASLKWPVHNHLSQYPHFLWFDLSNPDIYITLIAGILYFIQSLVSLGNMPQEQRQMGYMMMVISPIFIIYISFTSASALGLYWSINALFLIIQMYFSNQYYSKIADEYVKSFEKQNDKKSQKAKTIKKKK

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Crispr_ID: LR134242_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134242_2

108588-108951

TypeII

Consensus_repeat	Method
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	PILER-CR
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CRISPRCasFinder
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CRT

5 spacers

cas2,cas1,cas9

The CRISPR arrays of LR134242_2

>merge|LR134242|2|108588-108951|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACTTTCATTATTGGCTTATTCATCATATTTTGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACCAGGATATGCTTATTTGTTTGCGATTATATGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACATATCAAATGCTTAACTTAGGTAAATATCGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACTCCTGCATACGAAAATACTTCAATCAGTGCGTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAACGCTTTTTGAAAAATACAACTGAAGCTTTTAGTTTTAGTACTCTGTAATTTTAGGTATGAAGTAGAT

>LR134242|2|2|108588-108885|PILER-CR
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTCATTATTGGCTTATTCATCATATTTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CAGGATATGCTTATTTGTTTGCGATTATAT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	ATATCAAATGCTTAACTTAGGTAAATATC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TCCTGCATACGAAAATACTTCAATCAGTGC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC

>LR134242|2|2|108588-108951|CRISPRCasFinder
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTCATTATTGGCTTATTCATCATATTTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CAGGATATGCTTATTTGTTTGCGATTATAT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	ATATCAAATGCTTAACTTAGGTAAATATC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TCCTGCATACGAAAATACTTCAATCAGTGC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	GCTTTTTGAAAAATACAACTGAAGCTTTTA
GTTTTAGTACTCTGTAATTTTAGGTATGAAGTAGAT

>LR134242|2|2|108588-108951|CRT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TTTCATTATTGGCTTATTCATCATATTTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	CAGGATATGCTTATTTGTTTGCGATTATAT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	ATATCAAATGCTTAACTTAGGTAAATATC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	TCCTGCATACGAAAATACTTCAATCAGTGC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGAAAC	GCTTTTTGAAAAATACAACTGAAGCTTTTA
GTTTTAGTACTCTGTAATTTTAGGTATGAAGTAGAT

Protein	Signature genes	Signature genes Name	Protein_function
LR134242.1\|VED25510.1\|101256_102195_+\|putative-dioxygenase	unknown	unknown	gnl\|CDD\|319935
LR134242.1\|VED25522.1\|110702_111041_+\|MazG-like-family	unknown	unknown	gnl\|CDD\|212144
LR134242.1\|VED25516.1\|107238_107547_+\|CRISPR-associated-protein-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LR134242.1\|VED25512.1\|103164_106329_+\|CRISPR-associated-protein,-Csn1-family	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
LR134242.1\|VED25502.1\|97064_97934_+\|peptide-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|131837
LR134242.1\|VED25508.1\|99499_100678_+\|transporter	unknown	unknown	gnl\|CDD\|341042
LR134242.1\|VED25506.1\|98738_99488_+\|oligopeptide-transporter-putative-ATPase-domain-protein	unknown	unknown	gnl\|CDD\|224049
LR134242.1\|VED25536.1\|120297_120864_-\|LPXTG-motif-surface-anchored-protein	unknown	unknown	gnl\|CDD\|273478
LR134242.1\|VED25514.1\|106331_107234_+\|CRISPR-associated-protein-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
LR134242.1\|VED25500.1\|96132_97068_+\|oligopeptide-transporter-putative-membrane-permease	unknown	unknown	gnl\|CDD\|223674
LR134242.1\|VED25520.1\|108963_110697_+\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|378274
LR134242.1\|VED25538.1\|121133_121262_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134242.1\|VED25504.1\|97930_98746_+\|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein	unknown	unknown	gnl\|CDD\|223521
LR134242.1\|VED25524.1\|111159_113019_+\|Activator-of-the-mannose-operon-(transcriptional-antiterminator),-BglG-family	unknown	unknown	gnl\|CDD\|226234
LR134242.1\|VED25518.1\|107560_108568_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134242.1\|VED25530.1\|116254_117091_+\|putative-lipoprotein	unknown	unknown	gnl\|CDD\|235040
LR134242.1\|VED25534.1\|119163_120243_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134242.1\|VED25532.1\|117896_118505_+\|membrane-protein	unknown	unknown	gnl\|CDD\|376676
LR134242.1\|VED25528.1\|115068_116004_+\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
LR134242.1\|VED25526.1\|113098_115054_+\|putative-fructose-phosphotransferase-system-enzyme-fruA	unknown	unknown	gnl\|CDD\|224218

Protein	Function_ID	Function_description	E-value
LR134242.1\|VED25510.1\|101256_102195_+\|putative-dioxygenase	gnl\|CDD\|319935	cd08347, PcpA_C_like, C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The C-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	7.96148e-41
LR134242.1\|VED25522.1\|110702_111041_+\|MazG-like-family	gnl\|CDD\|212144	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs. RS21-C6 proteins, highly expressed in all vertebrate genomes and green plants, act as house-cleaning enzymes, removing 5-methyl dCTP (m5dCTP) in order to prevent gene silencing. They show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, RS21-C6 contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. Divalent ions, such as Mg2+, are required for its pyrophosphatase activity. This family also includes a pyrophosphatase from Archaeoglobus fulgidus (Af1178). Although its biological role remains unclear, Af1178 shows significant sequence similarity to the mouse RS21-C6 protein.	4.56263e-36
LR134242.1\|VED25516.1\|107238_107547_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.07146e-32
LR134242.1\|VED25512.1\|103164_106329_+\|CRISPR-associated-protein,-Csn1-family	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	1.20067e-112
LR134242.1\|VED25502.1\|97064_97934_+\|peptide-ABC-transporter-permease	gnl\|CDD\|131837	TIGR02790, Nickel_transport_system_permease_protein_nikC., nickel ABC transporter, permease subunit NikC. This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds].	4.02182e-83
LR134242.1\|VED25508.1\|99499_100678_+\|transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.29023e-68
LR134242.1\|VED25506.1\|98738_99488_+\|oligopeptide-transporter-putative-ATPase-domain-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.14345e-99
LR134242.1\|VED25536.1\|120297_120864_-\|LPXTG-motif-surface-anchored-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	0.00170781
LR134242.1\|VED25514.1\|106331_107234_+\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	8.75615e-98
LR134242.1\|VED25500.1\|96132_97068_+\|oligopeptide-transporter-putative-membrane-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.57629e-97
LR134242.1\|VED25520.1\|108963_110697_+\|Uncharacterized-conserved-protein	gnl\|CDD\|378274	pfam09848, DUF2075, Uncharacterized conserved protein (DUF2075). This domain, found in various prokaryotic proteins (including putative ATP/GTP binding proteins), has no known function.	1.87642e-100
LR134242.1\|VED25504.1\|97930_98746_+\|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.64867e-112
LR134242.1\|VED25524.1\|111159_113019_+\|Activator-of-the-mannose-operon-(transcriptional-antiterminator),-BglG-family	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.1389e-32
LR134242.1\|VED25530.1\|116254_117091_+\|putative-lipoprotein	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	3.72427e-59
LR134242.1\|VED25532.1\|117896_118505_+\|membrane-protein	gnl\|CDD\|376676	pfam01944, SpoIIM, Stage II sporulation protein M. SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.	1.23287e-05
LR134242.1\|VED25528.1\|115068_116004_+\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	1.95336e-127
LR134242.1\|VED25526.1\|113098_115054_+\|putative-fructose-phosphotransferase-system-enzyme-fruA	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	4.39486e-148

>LR134242.1|VED25518.1|107560_108568_+|Uncharacterised-protein
MTNLQWCIKTDSLPTITLNIGKYTAIYNEYETIEEDLLNVINQYFKKRNSNKSNVTIAEMLNQEEISPLSYESIIIDNRAIDNEFLLSSNSIINKKLQRDFYENIESNSYIESINVLFEDLLNLINKAELPLKSKTFDIKQFIKLLSFEYSLNEDYSKLIVRIEQILPLLVEELNKQYGGKLLLIYLYPEANLSPKEQIRLKELIISLGIDIIVLTGSLHFLAEDWKYNNYIRCDNQKISSELVDNLLWNAPLNFERSEIEQSLNQFILAYQDKIEIKPIISNYQIAQIMLFSSIDLYVGVSYMQHCNHEFILNIDETKLPLSMAKYLEQFVKEN
>LR134242.1|VED25516.1|107238_107547_+|CRISPR-associated-protein-Cas2
MRVLLMFDLPTETKKHRRIYSKFRKNLIEDGFLMMQYSIYIKSVVNKDAANQTIKRVNTFLPSEGHVRALIITEKQYEHMQILLGEENQNIEILGDNRTIIF
>LR134242.1|VED25514.1|106331_107234_+|CRISPR-associated-protein-Cas1
MSWRIVYVSDVNHMSLNLNSLKIMKGDLETKIPLSDIFALVIEDLTTTITARLLVELSDYNILVIFCNQKHLPECTLQPVSGHFNQYTQMKEQLKWDEARKSELWKIIIENKIQNQIECMKYLSIQSDRVDKMIELKNSVTLFDRNNIEGQAAKYYFNSFFEDFTRDNEEIIENAVLNYGYTILNSAIARTIVAKGLIPAIGIHHIGGRNHFNLASDLIEPFRPIVDLFLLKHPPQDFLTKEYRVKIINLLHARIEIDGKMQTVIRAIEIMIQSIIDYFKDGQLDRVKFPKLSKYSFYEL
>LR134242.1|VED25512.1|103164_106329_+|CRISPR-associated-protein,-Csn1-family
MKEKYILGLDLGITSVGYGIINFETKKIIDAGVRLFPEANVDNNEGRRSKRGSRRLKRRRIHRLDRVKSLLTEYNLINREQIPTSNNPYQIRVKGLSEILSKDELAIALLHLAKRRGIHNINVSSEDEDASNELSTKEQINRNNKLLKNKYVCEVQLQRLKEGQIRGEKNRFKTTDILKEIDQLLKVQKDYHNLDIDFINQYKEIVETRREYFEGPGQGSPFGWNGDLKKWYEMLMGHCTYFPQELRSVKYAYSADLFNALNDLNNLIIQRNDSEKLEYHEKYHIIENVFKQKKKPTLKQIAKEIGVNPEDIKGYRITKSGTPQFTEFKLYHDLKSIVFDKSILENEAILDQIAEILTIYQDEESIKEELNKLPEILNEQDKAEIAKLTGYNGTHRLSLKCIHLINEELWQTSRNQMEIFNYLNIKPNKVDLSEQNKIPKDLVDEFILSPVVKRTFIQSINVINKVIEKYGIPEDIIIELARENNSDDRKKFINNLQKKNEATRKRINEIIGQTGNQNAKRIVEKIRLHDQQEGKCLYSLESIPLMDLLNNPQNYEVDHIIPRSVAFDNSIHNKVLVKQIENSKKGNRTPYQYLNSSDANLSYNQFKQHILNLSKSKDRISKKKKDYLLEERDINKFEVQKEFINRNLVDTRYATRELTSYLKAYFSANNMDVKVKTINGSFTNHLRKVWRFDKYRNHGYKHHAEDALIIANADFLFKENKKLQNANKILEKPTIENDTQKVTVEKEEDYNNMFETPKLVEDIKQYRDYKFSHRVDKKPNRQLIKDTLYSTRMKDEHNYIVQTITDIYGKDNTNLKKQFNKNPEKFLMYQNDPKTFEKLSIIMKQYSDEKNPLAKYYEETGEYLTKYSKKNNGPIVKKIKLLGNKVGNHLDVTNKYENSTKKLVKLSIKNYRFDVYLTEKGYKFVTIAYLNVFKKDNYYYIPKDLYQELKAKKKIKDTDQFIASFYKNDLIKLNGDLYKIIGVNSDDRNIIELDYYDIKYKDYCEINNIKGEPRIKKTIGKKTESIEKLTTDVLGNLYLHTTEKAPQLIFKRGL
>LR134242.1|VED25510.1|101256_102195_+|putative-dioxygenase
MTIVGHHHISMYTKDAVKNKAFYTELLGLRLVEKTVNQDNTKMYHLFYGDNAGHPGTLLTFFEIENVGKHRPGTDSIHRLTLLVPSETALDYFKQRLDQNNVEWTSLLYLDQSAVLLKDPDELEIILLVNDDYQTPEQWSANDDTVIPKDVQILGMGPVELRSRKPEALTEFLEHILGYHQRNDLEADDNTTIMTLDEQGLYTDFVIVNQQGHRVRPGQGYVHHVAVNLPTDTDLNDIYEKIARQPNPNSGIIDRYFFKSLYYRHNQILFEFATAEPGFTVDTPVAKLGQQLNLPDFLEDKRDEIESQLREI
>LR134242.1|VED25508.1|99499_100678_+|transporter
MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTTIGIVMGVYMLTAMVFRPWAGQIIARVGPIKVLRIILLINACALILYGLTGLEGYFIARVMQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLVGPLIAVGIWHLDRISIFAIVMIAIALTTTFFGYRVTFASEEPDTRKKVEPLPFNAVTVFAQFFKNKELFNSGLIMIVVSIVFGAVSTFVPLYTVKFGFADAGILLTIQAIAVVLARIYLRKYIPSDGIWHPVYMVSVLMLLVIASMLVAIGPHIHVLIFYSSAILIGATQALVYPTLTSYLSFVLPKAGRNMLLGLFIACADLGVSLGGSLMGPISDLVGFSWMYTICGMLVVVMMLMSAFKGIRQK
>LR134242.1|VED25506.1|98738_99488_+|oligopeptide-transporter-putative-ATPase-domain-protein
MIKINHVEKHYGKRSLWGPKPKPIIKDVSLDCPVDEAIAIIGESGSGKSTLSRMILGIERPDKGTVTLNDQPMYKKKVRRHQIGAVFQDYTSSLHPFQTVRDILFEVMCQCDKQSTDEMEGAAKTLLEEVGLSEDFLDKYPNMLSGGEAQRVAIARAICINPTYILFDEAISALDMSIQTQILDLLKRLKHTRHLSYIFITHDIQAATYLCDRLVIFKDGQIEEQIATRDLHTTTNAYTQALIDKQLSF
>LR134242.1|VED25504.1|97930_98746_+|ABC-superfamily-ATP-binding-cassette-transporter,-ABC-protein
MTLLTVQQLTIRDEWTDTTLVDDINFQVKRGETLGIIGESGSGKSITCKALVELNPSRLKVTGKVHFDGHNLLALSERQLRQYRGQAIAMVMQQGARAFDPSTKVGKQMIETMQVHTSLSTQEVEQTLIDYMTYMNLTDPQNILASYPYMLSGGMLQRLMIALALALKPKLIIADEPTTALDTINQFDVLEAFEDIKQHFDCAMIFISHDLAVIHKVADRVIVMKEGQLVEEGTTEAVLHHPHHRYTQYLLSTKQKVNDHFQRVMRGDSHD
>LR134242.1|VED25502.1|97064_97934_+|peptide-ABC-transporter-permease
MMIVKRLLQDRGAVVALVIIATYFLLGFLAPVITFHEPNHIDTAHKFAGISATHWLGTDHLGRDVLTRLIYAIRPSLLYVSIALVISVAIGAILGFISGYFRGYIDALIMRCCDVMLAFPSYVVTLALITLFGMGVENIILAFILTRWAWFCRVIRTSVMQYTSADHVKFAKTIGMSDFTIIRKHILPLTLGDIAIISSSAMCSMILQMSGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPGMMVTTGIVIVIIVMAFNFLSDALQVAMDPRISSKEKMRAVKKGVMHE
>LR134242.1|VED25500.1|96132_97068_+|oligopeptide-transporter-putative-membrane-permease
MFKLIIKRIALMFPLLIVVSFMTFMMTYLTNEDPAVTILHAQGTPNVTPQLIAETKEKYGLDAPILVQYKDWLQQAVQFKFGTSYITGDPVSERIGPAFMNTLKLTLISSVSVMVTSICLGVVSALTRGQRTDRVIRSVAFFLTALPSYWVASMLIIYVSVKLNLLPTSGLTGPESYVLPVVVITMSYAGIYFRNVRRAMIEQLNEDYVLYLKASGVKTMTLLRHVLRNALQVAVSIFCMSIPMIMGGLVVIENVFAWPGLGQLSIKAIVEHDFPVVQTYVLIVAVLFIIFNTLADIINALLNPRLREASR
>LR134242.1|VED25520.1|108963_110697_+|Uncharacterized-conserved-protein
MSSMRKPIIKNISYSNEELVNSLGEWQQSDDSKFLLRYPTVYIINDKNKSDHFNLYVGETTDIKNRTIQHLKNDVKLKDYWKSFYSSDTSSMYVIGHPFFNKSLTLDIENKFMQYLSSVDAVNSIFNSRTNQQNEYYTSEKLDEIFTNIWQQLHKENSKLFPIESVIKDSAIFKASPFHKLTNEQQSVKDEILNKIEHAILSESEENQLILVEGEAGSGKTVLMSTLFFELKQMMDLDEMKNLDIHLLVNHDQQLKVYKQIANKLGLEGKNQNIINKPTSFILNRDVEDKADVVIIDEAHLLLTQGKMSYRGEGHLKDIQKRAKVVVAVFDKKQILSKQQIWEFDTLDKLIQYSKDQNNHLLLKNQLRINSSIETMNWLRHLIDDHKIDPIPHDSKGYDIKIFDTPAELEKAILRKTKNIESGLSRMLATFDWEFKNGKSPNDGLFWEVKIGQWSRPWNLQLKCPRGEKNLAWPEQSQTINEIGSTFTIQGFDLNYAGVIIGPSVKFRNGKIIYDKSESKNIQVTQNRKLSDDTMKNFGEELLRNELNVLLTRGVNGLYIYAVDDELRNALKEASKG
>LR134242.1|VED25522.1|110702_111041_+|MazG-like-family
MRTENSVMEKINQFRDERNWRQFHNEKDLALSITLEASELLELFQWKSSEDVVESKRERLAEELADILIYSYMFADNLDFDINEIIEQKLVKNAEKYPVDKSKDNNSKYNEL
>LR134242.1|VED25524.1|111159_113019_+|Activator-of-the-mannose-operon-(transcriptional-antiterminator),-BglG-family
MIERQIKLIELLRNNRSDYLKSDDIAAYLNISNRTARTDIKIINNQFMPEVIGNIKSKGYFLNTTRYSLEDIDNQLSNYLNQDGKLLIKIAYQLLMYSTSVLISELMEQFQLSKKEILDYMSRIQMWCEKYEVNIIIKRKTGITVTGNEKDINNAILHLNQLSKQHHRVEDLILNELPKAHIQMIKQIIEDNLSVHDIRTSHLQIEQLVIHLILILKRQSISEESWNINDESLVISNEIIKDINQRLGYHLNTQTVQLFSFFISYHFNKFDLGFEKVFIESYIQQLITKMEQKMHLKFGSDNVLKDNLLAHFSRTYLRIMKEVYLNNPLTGEIKILYPYVFNVLYDIIHELAKDTGINLSEDEIAFLTIHFQASIDRNEVSQVNIAICCYYGLGISQLLETKISKVNQHVKVTDILRFEDIENDAFENIDILITTHDIHMQLPQDLDVIKVSPLFSEDDQFKLNRIVKGKLNPIAKNNELNEIPVTIVNNDFIQTIPGVFETAHQILNNYKAISSGYIETALNREKASSTYIGNSMTMPHGDPTKVLSSNIIIFKSNNGFYWKEHKIKLVFFLAIAKPDIHLMKQMMQNLSLLDEEDIHQLAHLEETTFQNKILKLIKG
>LR134242.1|VED25526.1|113098_115054_+|putative-fructose-phosphotransferase-system-enzyme-fruA
MKILAITSCPNGIAHTYMAQEKLEQAAKKMGVDIKVETQGGVGAENVLTTKEIREADGIIIAADRQVDLSRFNGKRLINENVREGIHHPETLIQRIIDQDAKIYHDKNATTQSNDSDDEEDRKSGIQMVYQHLMNGVSFMVPFIVVGGLLIAIALTLGGHPTSEGLKIPDDSFWKSIENIGKLSFGFMVPILAGYIAYSIADKPGLVPGMIGGAIAADGSLYGSEAGAGFLGGIVAGFIAGYVAKWIKNIRVPKAMAPIMPIIIIPILASLIVGLIFIFLIGAPISGIFTALTGWLKGMQGANIIILALIIGAMIAFDMGGPVNKVAFLFGSALIAEGNYAVMGMVAVAVCTPPIGLGLATFVQKHKFNHAEQEMGKASFTMGLFGITEGAIPFAAQDPLRIIPSNMIGAMVAAVIAAMGGVGDRVAHGGPIVAVLGGIDHIIWFFIAVIIGSLVTMITILILKRNTPVTDVEEDQEDTHLERSTNSSQGSKYSESKVDESVKHDDNVFQKDVININTNVKTKEEAIDYMVKNLKEHRFIDNEDVVKQAILDREAESTTAIGMNVAIPHAKSDAVNQPTVAVLQNKEGIDWISLDESLPKILFMIVVPNDSNNTHLKLLQRLSRSLMDDKTREALINAPSKDDIYDILKEI
>LR134242.1|VED25528.1|115068_116004_+|mannose-6-phosphate-isomerase
MALFLKPVFQEKIWGGTALESFNYHLPSNNVGECWAISAHPNGPNVIENGHYKGKTLDEVWSIDRSLFGNDKRDKFPLLTKILDANDKLSVQVHPDDDYAQKYEGEYGKTECWYILDAKEDAEIIYGINVDNKEDLVECINNREFDRLFKKVKVKPGDFYYVPAGTVHAIGSGILILETQQSSDTTYRIYDYDRKDKHGHLRDLHLEQSKAVININQENPNVVPQQSEVQGQTVTQFVSNEFFTVEKWRINGKLNYKKPHAYCLVSVIDGTGSVIIDDERHDIQKGRHFIITNEDQNILFDGKLEIIISYS
>LR134242.1|VED25530.1|116254_117091_+|putative-lipoprotein
MKLKYVILVLLAPVFLSACNYSKPENRNGFFYNTFAKPMDLFLNWMGEHLNHNYGLAIIIIVLAIRLIMLPFMLSQTKNGQFMRKLMKIAKPELDPIQEKVRRARTQEEKMDANKEMMDVYKKYHINPMKSMLGCLPMLIQMPILFGLYASLKWPVHNHLSQYPHFLWFDLSNPDIYITLIAGILYFIQSLVSLGNMPQEQRQMGYMMMVISPIFIIYISFTSASALGLYWSINALFLIIQMYFSNQYYSKIADEYVKSFEKQNDKKSQKAKTIKKKK
>LR134242.1|VED25532.1|117896_118505_+|membrane-protein
MLNISDKQYVQRTTKWFVFAMIILIISFILSTIFSPSLDTFKSIGDQTPSSLDKATGLNKVWEFIINNGFRVPIQMLILSLIPIPFLYCVNLIFTSTITGIMFGFVINFDFHKGSIVILSSIPHIVVEIFAMCFVVSSLFKLNQAIVRKISNLFRKEKKQKVSFKQALIQLIKTYILIALPLYIIAAFLETYFTEWIYSILI
>LR134242.1|VED25534.1|119163_120243_+|Uncharacterised-protein
MKNLSIQSVDSFKSKYKSVPDNKVLRNMNSDELESYFLMLYNIRNTINQGQAQYNKLLKNNNDKKNRKIETITSEYNERQETLKYYTPETDKIDAKYKQRRDSIVKPINIICKVVSVIIAVIVFLNLFFISKILATILCFVTYKMVDLILSFVGGFIERRIYKAKYREWTVARALDQDYFNREIARCEAQFESDKQYILSEHKRFDSKIRNDYQSIYTHFENEAQKLETYLPSEFRSLDILSTLFAILNAGFGDSWKEIINVYRDQKNMNELKSHINDIQNTLNSMCNNQKATIQAINHQGQQQQRLLNELNVGIQQSNNNIEKLTNDINRGYEKVQRNQKAIHDELADMNPHNPRSKY
>LR134242.1|VED25536.1|120297_120864_-|LPXTG-motif-surface-anchored-protein
MKTTKILGATTLAGALLFTGVSSHNASAAESSVNANNAQSVATQVWKEDGYKPERVNFQKAEDKGDYYLLGYNNKSGVGDGAVRVYKDGTVETGEGVLATADDGKFYKNGKYQFDNSNNNEQGQQQATDNTVTTQNNNQQQAVQNNATQAQELPATGETTNNGLVASIATVLLAIGSLLTFKRFSKEK
>LR134242.1|VED25538.1|121133_121262_-|Uncharacterised-protein
MTESDFKKYNQLVGDRQLPGDVAQRTGHNGVLSDDLATENDE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	CP018841	Staphylococcus phage HOB 14.1.R1, complete genome	14866-14894	1	0.966
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	KY653117	Staphylococcus phage IME1323_01, complete genome	38640-38668	2	0.931
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	NC_019914	Staphylococcus phage StB27, complete genome	35427-35455	2	0.931
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	NC_007055	Staphylococcus phage 37, complete genome	21235-21263	3	0.897
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	JN700520	Staphylococcus phage StB12, complete genome	38917-38945	3	0.897
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	KY653116	Staphylococcus phage IME1318_01, complete genome	37953-37981	3	0.897
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	NC_024391	Staphylococcus phage DW2, complete genome	36560-36588	3	0.897
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	AY954958	Bacteriophage 37, complete genome	21235-21263	3	0.897
LR134242_1	1.6\|102717\|30\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102717-102746	30	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	211071-211100	6	0.8
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	AP013402	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S38-C27	14570-14598	6	0.793
LR134242_2	2.4\|108820\|30\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108820-108849	30	NZ_AP018257	Calothrix sp. NIES-4071 plasmid plasmid2 DNA, complete genome	3483-3512	6	0.8
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	MN693979	Marine virus AFVG_250M571, complete genome	14928-14957	6	0.8
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	MN694171	Marine virus AFVG_250M572, complete genome	38802-38831	6	0.8
LR134242_1	1.1\|102388\|30\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102388-102417	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	364899-364928	7	0.767
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP040343	Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence	333666-333694	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP033789	Bacillus sp. FDAARGOS_527 plasmid unnamed2, complete sequence	243170-243198	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	197412-197440	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP053290	Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence	376842-376870	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP016317	Bacillus cereus strain M3 plasmid pBCM301, complete sequence	42627-42655	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	126805-126833	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	178505-178533	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	234914-234942	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	227339-227367	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	109762-109790	7	0.759
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	233783-233811	7	0.759
LR134242_1	1.6\|102717\|30\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102717-102746	30	MN693417	Marine virus AFVG_25M193, complete genome	16281-16310	7	0.767
LR134242_2	2.1\|108624\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108624-108652	29	NZ_CP041715	Legionella geestiana strain HL-0438-4026 plasmid unnamed2, complete sequence	9981-10009	7	0.759
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	NC_009036	Shewanella baltica OS155 plasmid pSbal02, complete sequence	86-115	7	0.767
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	NC_017578	Shewanella baltica OS117 plasmid pSBAL11703, complete sequence	38059-38088	7	0.767
LR134242_1	1.6\|102717\|30\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102717-102746	30	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	116747-116776	8	0.733
LR134242_2	2.3\|108755\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	108755-108783	29	MN062185	Vibrio phage Phriendly, complete genome	9008-9036	8	0.724
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	MF001355	Proteus phage PM2, partial genome	3594-3623	8	0.733
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024318	Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-1	23855-23883	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024323	Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-4	2506-2534	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024207	Borrelia miyamotoi strain Izh-5 plasmid pIzh5-1	23927-23955	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024213	Borrelia miyamotoi strain Izh-5 plasmid pIzh5-6	17711-17739	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024335	Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-1	23862-23890	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024353	Borrelia miyamotoi strain Izh-16 plasmid pIzh16-1	23865-23893	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024366	Borrelia miyamotoi strain Izh-16 plasmid pIzh16-11	3372-3400	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024392	Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp70, complete sequence	46184-46212	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024401	Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp64, complete sequence	46340-46368	9	0.69
LR134242_1	1.3\|102520\|29\|LR134242\|PILER-CR,CRISPRCasFinder,CRT	102520-102548	29	NZ_CP024373	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-1	46221-46249	9	0.69
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	NZ_CP031226	Pseudomonas amygdali pv. lachrymans str. M301315 plasmid pMPPla107, complete sequence	268867-268896	9	0.7
LR134242_2	2.5\|108886\|30\|LR134242\|CRISPRCasFinder,CRT	108886-108915	30	AP014503	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S42-C30, * SEQUENCING IN PROGRESS *, 2 ordered pieces	23285-23314	9	0.7

1. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to CP018841 (Staphylococcus phage HOB 14.1.R1, complete genome) position: , mismatch: 1, identity: 0.966

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
atatcaaatgcttaatttaggtaaatatc	Protospacer
***************.*************

2. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to KY653117 (Staphylococcus phage IME1323_01, complete genome) position: , mismatch: 2, identity: 0.931

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
atatcaaatgcttaatttaggtaagtatc	Protospacer
***************.********.****

3. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_019914 (Staphylococcus phage StB27, complete genome) position: , mismatch: 2, identity: 0.931

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
ataccaaatgcttaacttaggtaagtatc	Protospacer
***.********************.****

4. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_007055 (Staphylococcus phage 37, complete genome) position: , mismatch: 3, identity: 0.897

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
ttatcaaatgcttaatttaggtaagtatc	Protospacer
 **************.********.****

5. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to JN700520 (Staphylococcus phage StB12, complete genome) position: , mismatch: 3, identity: 0.897

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
gtatcaaatgcttaatttaggtaagtatc	Protospacer
.**************.********.****

6. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to KY653116 (Staphylococcus phage IME1318_01, complete genome) position: , mismatch: 3, identity: 0.897

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
ttatcaaatgcttaatttaggcaaatatc	Protospacer
 **************.*****.*******

7. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_024391 (Staphylococcus phage DW2, complete genome) position: , mismatch: 3, identity: 0.897

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
ctatcaaatgcttaatttaggtaagtatc	Protospacer
 **************.********.****

8. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to AY954958 (Bacteriophage 37, complete genome) position: , mismatch: 3, identity: 0.897

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
ttatcaaatgcttaatttaggtaagtatc	Protospacer
 **************.********.****

9. spacer 1.6|102717|30|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 6, identity: 0.8

aaactgatttagcagtgtttaatggtggtt	CRISPR spacer
aacctgattttgcagtgtttaatgcagtat	Protospacer
** ******* *************  *  *

10. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to AP013402 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S38-C27) position: , mismatch: 6, identity: 0.793

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
tttttaaatacttaacataggtaaatatg	Protospacer
 * *.****.****** ***********

11. spacer 2.4|108820|30|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018257 (Calothrix sp. NIES-4071 plasmid plasmid2 DNA, complete genome) position: , mismatch: 6, identity: 0.8

tcctgcatacgaaaatacttcaatcagtgc	CRISPR spacer
tcctgcatacccaaatacttcaatacctgg	Protospacer
**********  ************   **

12. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to MN693979 (Marine virus AFVG_250M571, complete genome) position: , mismatch: 6, identity: 0.8

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
gaatatagaaaaatacaactgaagctgttg	Protospacer
*  * * ******************* **.

13. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to MN694171 (Marine virus AFVG_250M572, complete genome) position: , mismatch: 6, identity: 0.8

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
gaatatagaaaaatacaactgaagctgttg	Protospacer
*  * * ******************* **.

14. spacer 1.1|102388|30|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 7, identity: 0.767

aaaccatgtatccctcgttagtttttagat	CRISPR spacer
tatactcgtatccctcgttattttttggat	Protospacer
 *  * .************* *****.***

15. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040343 (Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

16. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033789 (Bacillus sp. FDAARGOS_527 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

17. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

18. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053290 (Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

19. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016317 (Bacillus cereus strain M3 plasmid pBCM301, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

20. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

21. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

22. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

23. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

24. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

25. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 7, identity: 0.759

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
ttcaggtatatttgtaagttgtacttgga	Protospacer
* .****** ************* **..

26. spacer 1.6|102717|30|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to MN693417 (Marine virus AFVG_25M193, complete genome) position: , mismatch: 7, identity: 0.767

aaactgatttagcagtgtttaatggtggtt	CRISPR spacer
caggtgatttagcagagtttaatgttgctg	Protospacer
 *. *********** ******** ** *

27. spacer 2.1|108624|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041715 (Legionella geestiana strain HL-0438-4026 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.759

tttcattattggcttattcatcatatttt	CRISPR spacer
aataattgttggattattcatcatattca	Protospacer
  * ***.**** **************.

28. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to NC_009036 (Shewanella baltica OS155 plasmid pSbal02, complete sequence) position: , mismatch: 7, identity: 0.767

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
ccgttttaaaaaataaaactgaagctgatt	Protospacer
 * ****.******* **********  *

29. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to NC_017578 (Shewanella baltica OS117 plasmid pSBAL11703, complete sequence) position: , mismatch: 7, identity: 0.767

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
ccgttttaaaaaataaaactgaagctgatt	Protospacer
 * ****.******* **********  *

30. spacer 1.6|102717|30|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

aaactgatttagcagtgtttaatggtggtt	CRISPR spacer
atccatgcatagcagcgtttaatggtggtt	Protospacer
*  *  .. ******.**************

31. spacer 2.3|108755|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to MN062185 (Vibrio phage Phriendly, complete genome) position: , mismatch: 8, identity: 0.724

atatcaaatgcttaacttaggtaaatatc	CRISPR spacer
tcatcaaatgtttaacttagctaaaccag	Protospacer
 .********.********* ****.

32. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to MF001355 (Proteus phage PM2, partial genome) position: , mismatch: 8, identity: 0.733

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
ggaaaatgaaaaatacacctgaagattttg	Protospacer
*     *********** ****** ****.

33. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024318 (Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-1) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

34. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024323 (Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-4) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

35. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024207 (Borrelia miyamotoi strain Izh-5 plasmid pIzh5-1) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

36. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024213 (Borrelia miyamotoi strain Izh-5 plasmid pIzh5-6) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

37. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024335 (Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-1) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

38. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024353 (Borrelia miyamotoi strain Izh-16 plasmid pIzh16-1) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

39. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024366 (Borrelia miyamotoi strain Izh-16 plasmid pIzh16-11) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

40. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024392 (Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp70, complete sequence) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

41. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024401 (Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp64, complete sequence) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

42. spacer 1.3|102520|29|LR134242|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024373 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-1) position: , mismatch: 9, identity: 0.69

tgtaggtatctttgtaagttgtaattaac	CRISPR spacer
caagagtaactttgtaagttgtaatttga	Protospacer
.. ..*** ***************** .

43. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to NZ_CP031226 (Pseudomonas amygdali pv. lachrymans str. M301315 plasmid pMPPla107, complete sequence) position: , mismatch: 9, identity: 0.7

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
acagaacaaaaaatacacctgaagcttttt	Protospacer
.*    ..********* ***********

44. spacer 2.5|108886|30|LR134242|CRISPRCasFinder,CRT matches to AP014503 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S42-C30, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 9, identity: 0.7

gctttttgaaaaatacaactgaagctttta	CRISPR spacer
taggtggagaaaatacaactgaagttttta	Protospacer
    *  ..***************.*****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

892880 : 904943

Staphylococcus_phage(56.25%)

integrase,terminase,transposase

attL 894828:894845|attR 907034:907051

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED27095.1\|892880_893168_+	co-chaperonin GroES	A0A221S4A5	uncultured_virus	6.2e-14	43.0
VED27097.1\|893222_894845_+	molecular chaperone GroEL	A0A240F779	uncultured_virus	7.6e-157	54.5
894828:894845	attL	NA	NA	NA	NA
VED27099.1\|894913_896089_-\|integrase	mobile element-associated integrase, putative	A0A2H4JBC4	uncultured_Caudovirales_phage	1.3e-211	95.1
VED27101.1\|896102_896777_-	mobile element-associated transcriptional regulator, putative	A0A2H4JGT9	uncultured_Caudovirales_phage	9.2e-40	46.2
VED27103.1\|896949_897168_+	mobile element-associated transcriptional regulator, putative	A0A2H4JB11	uncultured_Caudovirales_phage	2.2e-19	63.9
VED27105.1\|897172_897490_+	mobile element-associated transcriptional regulator, putative	A0A1W6JQE0	Staphylococcus_phage	8.9e-46	91.2
VED27107.1\|897486_897624_+	Uncharacterised protein	NA	NA	NA	NA
VED27109.1\|897625_898045_+	pathogenicity island protein	NA	NA	NA	NA
VED27111.1\|898044_898344_+	pathogenicity island protein	A0A2H4JB50	uncultured_Caudovirales_phage	2.8e-25	53.5
VED27113.1\|898434_899304_+	putative phage primase	A0A2H4JEH3	uncultured_Caudovirales_phage	1.2e-113	69.6
VED27115.1\|899316_900804_+	pathogenicity island protein	A0A1W6JQD6	Staphylococcus_phage	1.1e-255	87.4
VED27117.1\|901076_901439_+	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	6.0e-54	80.0
VED27119.1\|901440_902082_+\|transposase	transposase	Q4ZE67	Staphylococcus_phage	8.0e-94	77.0
VED27121.1\|902492_902834_+	pathogenicity island protein	A0A1W6JQF3	Staphylococcus_phage	7.1e-33	61.5
VED27123.1\|902863_903514_+	Uncharacterised protein	Q4ZE82	Staphylococcus_phage	2.0e-39	39.7
VED27125.1\|903575_904034_+	pathogenicity island protein	Q4ZE87	Staphylococcus_phage	3.9e-34	58.9
VED27127.1\|904036_904378_+\|transposase	transposase	A0A1W6JQM3	Staphylococcus_phage	1.5e-11	33.0
VED27129.1\|904382_904943_+\|terminase	putative phage terminase	Q4ZE85	Staphylococcus_phage	1.8e-57	60.2
907034:907051	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1025820 : 1062304

Staphylococcus_phage(96.15%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED27357.1\|1025820_1027230_+	O-succinylbenzoic acid-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.1e-172	63.0
VED27359.1\|1027219_1028233_+	o-succinylbenzoic acid synthetase	A0A2H4PQM0	Staphylococcus_phage	5.7e-102	55.9
VED27361.1\|1028216_1028456_-	Putative cytosolic protein	A0A2H4PQM5	Staphylococcus_phage	8.8e-38	90.1
VED27363.1\|1028516_1028990_+	MutT/NUDIX hydrolase family protein	A0A2H4PQM4	Staphylococcus_phage	8.1e-51	62.4
VED27365.1\|1028976_1029750_+	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	4.0e-108	76.5
VED27367.1\|1030224_1031817_-	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	9.7e-290	90.4
VED27369.1\|1032194_1033394_+	S-adenosylmethionine synthetase	A0A2H4PQS6	Staphylococcus_phage	4.0e-195	86.9
VED27371.1\|1033513_1034422_+	Uncharacterised protein	A0A2H4PQQ8	Staphylococcus_phage	2.8e-108	79.8
VED27373.1\|1034574_1035411_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.7e-107	69.1
VED27375.1\|1035470_1035830_-	CrcB family protein	NA	NA	NA	NA
VED27377.1\|1035826_1036189_-	camphor resistance protein CrcB	A0A2H4PQR0	Staphylococcus_phage	3.4e-33	65.0
VED27379.1\|1036328_1036634_-	membrane protein	NA	NA	NA	NA
VED27381.1\|1036889_1037603_+	Transaldolase	M1PR54	Cyanophage	3.2e-19	34.8
VED27383.1\|1037804_1038260_+	putative staphylococcal protein	A0A2H4PQT8	Staphylococcus_phage	1.4e-23	58.5
VED27385.1\|1038234_1038681_-	comK family protein	NA	NA	NA	NA
VED27387.1\|1038685_1039174_-	RNA polymerase sigma factor sigS	A0A2H4PQT5	Staphylococcus_phage	7.1e-34	52.0
VED27389.1\|1039366_1039591_+	putative staphylococcal protein	NA	NA	NA	NA
VED27391.1\|1039853_1040708_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JNR1	Staphylococcus_phage	2.2e-38	42.3
VED27393.1\|1041029_1042529_+	pyridine nucleotide-disulfide oxidoreductase family protein	A0A2H4PQX2	Staphylococcus_phage	4.7e-20	82.5
VED27395.1\|1043020_1044064_+	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-138	67.1
VED27397.1\|1044070_1044703_+	riboflavin synthase subunit alpha	A0A2H4PQS5	Staphylococcus_phage	4.8e-83	73.8
VED27399.1\|1044717_1045899_+	riboflavin biosynthesis protein	A0A2H4PQS2	Staphylococcus_phage	3.9e-179	77.6
VED27401.1\|1045911_1046370_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.7e-61	86.7
VED27403.1\|1046665_1047667_-	Proline dehydrogenase (Proline oxidase)	A0A2H4PQT6	Staphylococcus_phage	2.9e-143	78.0
VED27405.1\|1047899_1048727_+	lysophospholipase	NA	NA	NA	NA
VED27407.1\|1049130_1049532_+	repressor of toxins	NA	NA	NA	NA
VED27409.1\|1049585_1050149_-	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	9.0e-73	70.3
VED27411.1\|1050145_1051099_-	Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	3.0e-68	84.0
VED27413.1\|1051205_1052396_+	drug transporter	A0A2H4PQR6	Staphylococcus_phage	9.1e-176	79.1
VED27415.1\|1052679_1055094_+\|tRNA	leucyl-tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	87.5
VED27417.1\|1055117_1055429_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	8.5e-33	65.0
VED27419.1\|1055734_1062304_+	cell wall surface anchor family protein	A0A2H4PQU6	Staphylococcus_phage	2.4e-124	48.5

DBSCAN-SWA_3

1186515 : 1195540

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED27635.1\|1186515_1187520_+	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	2.0e-06	30.8
VED27637.1\|1187521_1188547_+\|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
VED27639.1\|1188568_1189708_+\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.4e-85	46.1
VED27642.1\|1189723_1189984_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	3.3e-06	42.6
VED27644.1\|1190323_1192603_+	bifunctional preprotein translocase subunit SecD/SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	3.1e-31	33.7
VED27646.1\|1192724_1195007_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	9.6e-65	29.5
VED27648.1\|1195021_1195540_+	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	7.3e-29	45.8

DBSCAN-SWA_4

1749091 : 1757561

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED28712.1\|1749091_1749658_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.7e-29	40.3
VED28714.1\|1749660_1750689_-	phosphoribosylaminoimidazole synthetase	Q58MH8	Prochlorococcus_phage	2.7e-67	45.0
VED28716.1\|1750681_1752166_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.7e-46	32.8
VED28718.1\|1752144_1754334_-	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	4.0e-137	37.8
VED28720.1\|1754326_1754998_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
VED28722.1\|1754999_1755260_-	phosphoribosylformylglycinamidine synthase, PurS protein	NA	NA	NA	NA
VED28724.1\|1755259_1755964_-	phosphoribosylaminoimidazole-succinocarboxamide synthase	G8EYA2	Synechococcus_phage	1.5e-48	43.8
VED28726.1\|1755964_1757092_-	phosphoribosylaminoimidazole carboxylase ATPase subunit	NA	NA	NA	NA
VED28728.1\|1757078_1757561_-	phosphoribosylaminoimidazole carboxylase PurE	A0A2P0VNU7	Tetraselmis_virus	4.4e-20	42.7

DBSCAN-SWA_5

1981263 : 1993011

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED29209.1\|1981263_1982232_-	FecCD transport family protein	A0A2H4IY97	uncultured_Caudovirales_phage	3.4e-144	81.7
VED29211.1\|1982457_1983432_-	ribonucleotide reductase of class Ib (aerobic), beta subunit	A0A2H4J4P3	uncultured_Caudovirales_phage	1.1e-179	96.3
VED29213.1\|1983676_1985782_-	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	93.7
VED29216.1\|1985744_1986143_-	ribonucleotide reductase stimulatory protein	A0A2H4J545	uncultured_Caudovirales_phage	2.4e-56	78.8
VED29218.1\|1986940_1987807_+	Integral membrane domain protein	NA	NA	NA	NA
VED29220.1\|1987830_1988331_+	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	3.8e-51	64.9
VED29222.1\|1988665_1990171_+	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	1.2e-55	31.7
VED29224.1\|1990320_1991250_+	putative diacylglycerol kinase protein	NA	NA	NA	NA
VED29226.1\|1991331_1991868_-	putative 5'(3')-deoxyribonucleotidase	A0A0A0PKY7	Bacillus_phage	2.9e-28	37.8
VED29228.1\|1991955_1993011_-	histidinol-phosphate aminotransferase	A0A0H3TLT9	Faustovirus	5.7e-20	27.4

DBSCAN-SWA_6

2005788 : 2012991

Pandoravirus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED29252.1\|2005788_2006937_-	para-aminobenzoate synthase component	S4VNU7	Pandoravirus	1.9e-24	40.1
VED29254.1\|2006920_2007514_-	para-aminobenzoate synthase, glutamine amidotransferase, component II	A0A0P0IKJ1	Acinetobacter_phage	2.9e-37	40.4
VED29256.1\|2007838_2008510_+	exoenzyme S synthesis protein B	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.2e-65	55.1
VED29258.1\|2008511_2008931_+	6-pyruvoyl tetrahydrobiopterin synthase	S4U060	uncultured_phage	1.7e-07	26.9
VED29260.1\|2008930_2009644_+	radical activating enzyme	E7DN68	Pneumococcus_phage	6.5e-52	42.7
VED29262.1\|2009746_2010346_+	Uncharacterised protein	NA	NA	NA	NA
VED29264.1\|2010812_2011919_-	glucosyl transferase	A8CG95	Salmonella_phage	1.4e-61	41.0
VED29266.1\|2012148_2012991_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.6e-52	41.7

DBSCAN-SWA_7

2350640 : 2367090

Staphylococcus_phage(70.59%)

terminase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED29896.1\|2350640_2351162_-\|terminase	putative phage terminase	Q4ZE85	Staphylococcus_phage	1.1e-56	63.2
VED29898.1\|2351166_2351508_-	pathogenicity island protein ORF6	A0A2H4JEH8	uncultured_Caudovirales_phage	4.8e-13	36.4
VED29900.1\|2351510_2351969_-	pathogenicity island protein	Q4ZE87	Staphylococcus_phage	1.8e-34	59.3
VED29902.1\|2352030_2352684_-	Uncharacterised protein	Q4ZE82	Staphylococcus_phage	7.3e-42	40.2
VED29904.1\|2352713_2353055_-	pathogenicity island protein	A0A1W6JQF3	Staphylococcus_phage	1.4e-33	62.4
VED29906.1\|2353619_2354261_-\|transposase	transposase	Q4ZE67	Staphylococcus_phage	5.9e-89	75.1
VED29908.1\|2354257_2354608_-	Phage protein	A0A2H4JHE6	uncultured_Caudovirales_phage	2.0e-38	72.5
VED29910.1\|2354878_2357131_-	DNA primase	A0A2H4JCU9	uncultured_Caudovirales_phage	0.0e+00	75.5
VED29912.1\|2357227_2357533_-	bovine pathogenicity island protein Orf16	Q4ZE75	Staphylococcus_phage	2.4e-32	66.3
VED29914.1\|2357532_2357895_-	pathogenicity island protein	NA	NA	NA	NA
VED29916.1\|2357896_2358109_-	pathogenicity island protein	Q4ZE76	Staphylococcus_phage	1.9e-15	59.7
VED29918.1\|2358110_2358266_-	Uncharacterised protein	NA	NA	NA	NA
VED29920.1\|2358278_2358551_-	pathogenicity island DNA-binding protein	Q4ZE77	Staphylococcus_phage	1.7e-16	40.0
VED29922.1\|2358551_2358716_-	putative DNA-binding protein	NA	NA	NA	NA
VED29924.1\|2358920_2359682_+	helix-turn-helix DNA binding protein	Q8SDV8	Staphylococcus_phage	5.7e-06	41.0
VED29926.1\|2359705_2360929_+	Integrase	Q4ZE80	Staphylococcus_phage	6.5e-177	79.3
VED29928.1\|2361155_2361398_-	30S ribosomalprotein S18p	NA	NA	NA	NA
VED29930.1\|2361442_2361958_-	single-strand DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	2.7e-60	73.1
VED29932.1\|2361979_2362276_-	30S ribosomal protein S6	NA	NA	NA	NA
VED29934.1\|2362651_2363473_+	1,4-beta-N-acetylmuramidase	A0A291I9H5	Lactobacillus_phage	1.8e-37	46.4
VED29936.1\|2363534_2363726_+	Uncharacterised protein	U3PCX8	Staphylococcus_phage	2.2e-23	81.7
VED29937.1\|2363891_2364989_-	GTP-binding and nucleic acid-binding protein YchF	NA	NA	NA	NA
VED29939.1\|2365000_2365204_-	Putative cytosolic protein	NA	NA	NA	NA
VED29941.1\|2365224_2366103_-	potassium efflux system KefA protein/Small-conductance mechanosensitive channel	NA	NA	NA	NA
VED29943.1\|2366250_2367090_-	transcription terminator	A0A1C9EHW0	Gordonia_phage	4.5e-12	33.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134242

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection