CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134283	Streptococcus anginosus strain NCTC10713 genome assembly, chromosome: 1	1 crisprs	cas1,cas2,csn2,csm6,WYL,DinG,csa3,cas3,DEDDh	0	17	6	0

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CRISPR-Cas detection and classification

Crispr_ID: LR134283_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134283_1

233522-235076

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRT

23 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of LR134283_1

>merge|LR134283|1|233522-235076|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTATACTGTTTTAATCCTCACACTCAAAGTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACACTAGCGTTAGAGCACGCACTACAGCATATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCTCAAAATGTGTCTTACCATACAGCGCAATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATTCCCGCGAGGAATATAAGTAATTCTCAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACACGGCGAGACCATGAGTGGTAAGTCTTATCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGATAAAGAAAGATAGGAGGTGAGTATCATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGCTTCTACTAATTGTTCATTCAAAGCGTCAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTAATCAAAACATCCAGCAACCAAGGCGACAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGCTATCTTTCTGCTATAATAAAAGCAGAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATTCTTCTTCAAAGCTCGACGAATGAGCTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTGGCGGGCGCGTTTGTCAATCACTTAGATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAAATAAGGTTTTGAATTTTCTTCTTCTTCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAATTTTTAGCCCCTCCATTTCCTCGACAAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTAAAGGGGAACGTGTTGACGTTCGTGGTATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGTCCTAGCTCAAAATCTCTGAAACTCCTATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAATTTTTAGCCCCCCCATTTCCTCGACAATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCTCCTGTTTTGCGCCCTTGGTTGCTGATATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCCCAATATTCGCTTTAAATTGTTCTGTCATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGAAACTGGTCGATTATTGGGTAGTCCCTTAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAGTCGGCAAGTGATGATGAGTTGCAAAGAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTAAAGGAATGTTGAAAGAACCATTTTATAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCAATCAGATTATTAAATTCCCCTAATTTGGGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATTATTTAGGATCAAAGCGAAGGTTGCATTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>LR134283|1|1|233522-235076|PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATACTGTTTTAATCCTCACACTCAAAGTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACTAGCGTTAGAGCACGCACTACAGCATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTCAAAATGTGTCTTACCATACAGCGCAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTCCCGCGAGGAATATAAGTAATTCTCAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACGGCGAGACCATGAGTGGTAAGTCTTATC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGATAAAGAAAGATAGGAGGTGAGTATCAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GCTTCTACTAATTGTTCATTCAAAGCGTCA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAATCAAAACATCCAGCAACCAAGGCGACA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCTATCTTTCTGCTATAATAAAAGCAGAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTCTTCTTCAAAGCTCGACGAATGAGCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTGGCGGGCGCGTTTGTCAATCACTTAGAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAAATAAGGTTTTGAATTTTCTTCTTCTTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATTTTTAGCCCCTCCATTTCCTCGACAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAAGGGGAACGTGTTGACGTTCGTGGTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GTCCTAGCTCAAAATCTCTGAAACTCCTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATTTTTAGCCCCCCCATTTCCTCGACAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTCCTGTTTTGCGCCCTTGGTTGCTGATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCCAATATTCGCTTTAAATTGTTCTGTCAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAAACTGGTCGATTATTGGGTAGTCCCTTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGTCGGCAAGTGATGATGAGTTGCAAAGAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAAGGAATGTTGAAAGAACCATTTTATAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CAATCAGATTATTAAATTCCCCTAATTTGG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTATTTAGGATCAAAGCGAAGGTTGCATT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>LR134283|1|1|233522-235076|CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATACTGTTTTAATCCTCACACTCAAAGTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACTAGCGTTAGAGCACGCACTACAGCATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTCAAAATGTGTCTTACCATACAGCGCAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTCCCGCGAGGAATATAAGTAATTCTCAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACGGCGAGACCATGAGTGGTAAGTCTTATC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGATAAAGAAAGATAGGAGGTGAGTATCAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GCTTCTACTAATTGTTCATTCAAAGCGTCA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAATCAAAACATCCAGCAACCAAGGCGACA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCTATCTTTCTGCTATAATAAAAGCAGAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTCTTCTTCAAAGCTCGACGAATGAGCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTGGCGGGCGCGTTTGTCAATCACTTAGAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAAATAAGGTTTTGAATTTTCTTCTTCTTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATTTTTAGCCCCTCCATTTCCTCGACAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAAGGGGAACGTGTTGACGTTCGTGGTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GTCCTAGCTCAAAATCTCTGAAACTCCTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATTTTTAGCCCCCCCATTTCCTCGACAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTCCTGTTTTGCGCCCTTGGTTGCTGATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCCAATATTCGCTTTAAATTGTTCTGTCAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAAACTGGTCGATTATTGGGTAGTCCCTTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGTCGGCAAGTGATGATGAGTTGCAAAGAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAAGGAATGTTGAAAGAACCATTTTATAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CAATCAGATTATTAAATTCCCCTAATTTGG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTATTTAGGATCAAAGCGAAGGTTGCATT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>LR134283|1|1|233522-235076|CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATACTGTTTTAATCCTCACACTCAAAGTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACTAGCGTTAGAGCACGCACTACAGCATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTCAAAATGTGTCTTACCATACAGCGCAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTCCCGCGAGGAATATAAGTAATTCTCAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ACGGCGAGACCATGAGTGGTAAGTCTTATC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGATAAAGAAAGATAGGAGGTGAGTATCAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GCTTCTACTAATTGTTCATTCAAAGCGTCA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAATCAAAACATCCAGCAACCAAGGCGACA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCTATCTTTCTGCTATAATAAAAGCAGAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTCTTCTTCAAAGCTCGACGAATGAGCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTGGCGGGCGCGTTTGTCAATCACTTAGAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAAATAAGGTTTTGAATTTTCTTCTTCTTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATTTTTAGCCCCTCCATTTCCTCGACAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAAGGGGAACGTGTTGACGTTCGTGGTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GTCCTAGCTCAAAATCTCTGAAACTCCTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATTTTTAGCCCCCCCATTTCCTCGACAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CTCCTGTTTTGCGCCCTTGGTTGCTGATAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CCCAATATTCGCTTTAAATTGTTCTGTCAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAAACTGGTCGATTATTGGGTAGTCCCTTA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAGTCGGCAAGTGATGATGAGTTGCAAAGAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAAGGAATGTTGAAAGAACCATTTTATAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CAATCAGATTATTAAATTCCCCTAATTTGG
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATTATTTAGGATCAAAGCGAAGGTTGCATT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134283.1\|VED97335.1\|222609_223308_+\|serine-type-D-Ala-D-Ala-carboxypeptidase	unknown	unknown	gnl\|CDD\|350624
LR134283.1\|VED97353.1\|245268_246012_+\|DeoR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
LR134283.1\|VED97349.1\|239519_242885_+\|ABC-superfamily-ATP-binding-cassette-transporter,-membrane-protein	unknown	unknown	gnl\|CDD\|274008
LR134283.1\|VED97339.1\|225192_225636_+\|flavodoxin	unknown	unknown	gnl\|CDD\|180922
LR134283.1\|VED97345.1\|235367_236009_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|238977
LR134283.1\|VED97336.1\|223333_223624_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|380358
LR134283.1\|VED97347.1\|238118_238667_-\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
LR134283.1\|VED97340.1\|225769_227155_+\|FeS-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
LR134283.1\|VED97348.1\|238803_239505_+\|ABC-transporter,-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
LR134283.1\|VED97338.1\|224102_225041_-\|DHH-subfamily-1-protein	unknown	unknown	gnl\|CDD\|223691
LR134283.1\|VED97341.1\|227380_231571_+\|CRISPR-associated-protein,-SAG0894-family	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
LR134283.1\|VED97354.1\|246030_246993_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
LR134283.1\|VED97337.1\|223753_224023_-\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234969
LR134283.1\|VED97350.1\|242976_243813_+\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|378975
LR134283.1\|VED97343.1\|232433_232778_+\|CRISPR-associated-protein-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LR134283.1\|VED97352.1\|244359_245136_-\|putative-glycyl-radical-enzyme-activating-protein	unknown	unknown	gnl\|CDD\|274163
LR134283.1\|VED97344.1\|232767_233430_+\|CRISPR-associated-protein,-SAG0897-family	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
LR134283.1\|VED97351.1\|243878_244316_+\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
LR134283.1\|VED97346.1\|236001_237954_+\|threonyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234752
LR134283.1\|VED97342.1\|231570_232437_+\|CRISPR-associated-protein-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
LR134283.1\|VED97335.1\|222609_223308_+\|serine-type-D-Ala-D-Ala-carboxypeptidase	gnl\|CDD\|350624	cd14852, LD-carboxypeptidase, L,D-carboxypeptidase DacB and LdcB, and related proteins. This L,D-carboxypeptidase family includes LdcB LD-Carboxypeptidase from Streptococcus pneumoniae, Bacillus anthracis, and Bacillus subtilis, and L,D-carboxypeptidase DacB from Streptococcus pneumonia and Lactococcus lactis. These enzymes are active against cell-wall-derived tetrapeptides and synthetic tetrapeptides lacking the sugar moiety but are inactive against tetrapeptides terminating in L-alanine. L,D-carboxypeptidase DacB plays a key role in the remodeling of S. pneumoniae peptidoglycan during cell division. It adopts a zinc-dependent carboxypeptidase fold and acts as an L,D-carboxypeptidase towards the tetrapeptide L-Ala-D-iGln-L-Lys-D-Ala of the peptidoglycan stem. This family also includes vanY D-Ala-D-Ala carboxypeptidase which is vancomycin-inducible and penicillin-resistant. VanY hydrolyzes depsipeptide- and D-alanyl-D-alanine-containing peptidoglycan precursors; it is insensitive to beta-lactams. All these enzymes belong to the MEROPS family M15 subfamily B.	1.65951e-60
LR134283.1\|VED97353.1\|245268_246012_+\|DeoR-family-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.65367e-78
LR134283.1\|VED97349.1\|239519_242885_+\|ABC-superfamily-ATP-binding-cassette-transporter,-membrane-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	1.93732e-19
LR134283.1\|VED97339.1\|225192_225636_+\|flavodoxin	gnl\|CDD\|180922	PRK07308, PRK07308, flavodoxin; Validated.	1.03052e-78
LR134283.1\|VED97345.1\|235367_236009_+\|Uncharacterised-protein	gnl\|CDD\|238977	cd02019, NK, Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.	5.32027e-05
LR134283.1\|VED97336.1\|223333_223624_+\|Uncharacterised-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	5.59533e-16
LR134283.1\|VED97347.1\|238118_238667_-\|putative-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.15118e-10
LR134283.1\|VED97340.1\|225769_227155_+\|FeS-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
LR134283.1\|VED97348.1\|238803_239505_+\|ABC-transporter,-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	8.55662e-105
LR134283.1\|VED97338.1\|224102_225041_-\|DHH-subfamily-1-protein	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	3.21941e-94
LR134283.1\|VED97341.1\|227380_231571_+\|CRISPR-associated-protein,-SAG0894-family	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	0
LR134283.1\|VED97354.1\|246030_246993_+\|transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	5.24391e-107
LR134283.1\|VED97337.1\|223753_224023_-\|50S-ribosomal-protein-L31	gnl\|CDD\|234969	PRK01678, rpmE2, type B 50S ribosomal protein L31.	8.927e-52
LR134283.1\|VED97350.1\|242976_243813_+\|serine/threonine-protein-phosphatase	gnl\|CDD\|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	8.63727e-15
LR134283.1\|VED97343.1\|232433_232778_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	5.8416e-46
LR134283.1\|VED97352.1\|244359_245136_-\|putative-glycyl-radical-enzyme-activating-protein	gnl\|CDD\|274163	TIGR02494, PFLE_PFLC, glycyl-radical enzyme activating protein. This subset of the radical-SAM family (pfam04055) includes a number of probable activating proteins acting on different enzymes all requiring an amino-acid-centered radical. The closest relatives to this family are the pyruvate-formate lyase activating enzyme (PflA, 1.97.1.4, TIGR02493) and the anaerobic ribonucleotide reductase activating enzyme (TIGR02491). Included within this subfamily are activators of hydroxyphenyl acetate decarboxylase (HdpA), benzylsuccinate synthase (BssD), gycerol dehydratase (DhaB2) as well as enzymes annotated in E. coli as activators of different isozymes of pyruvate-formate lyase (PFLC and PFLE) however, these appear to lack characterization and may activate enzymes with distinctive functions. Most of the sequence-level variability between these forms is concentrated within an N-terminal domain which follows a conserved group of three cysteines and contains a variable pattern of 0 to 8 additional cysteines.	3.02564e-102
LR134283.1\|VED97344.1\|232767_233430_+\|CRISPR-associated-protein,-SAG0897-family	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.4875e-105
LR134283.1\|VED97351.1\|243878_244316_+\|putative-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	1.29355e-30
LR134283.1\|VED97346.1\|236001_237954_+\|threonyl-tRNA-synthetase	gnl\|CDD\|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
LR134283.1\|VED97342.1\|231570_232437_+\|CRISPR-associated-protein-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.21132e-130

>LR134283.1|VED97344.1|232767_233430_+|CRISPR-associated-protein,-SAG0897-family
MKINFPILDEPIEIKQATFLILEEQLIFSDVVKHLYHYSEEDELKLFDNKMKSLKESELLLITDILGYNINSPAMLKLIRADLEKQLNEKSEVKSMLEKLVATITELIAFECLENELDLEYDEITILELIDALGVKIETLSDTVFEKSLEIVQVFKYLSKKKLLVFVNVSCYLSEHELAKLVEYIQLHNINVLFVEPRKVYDFPQYVVDEDYFLSCENMI
>LR134283.1|VED97343.1|232433_232778_+|CRISPR-associated-protein-Cas2
MSYRYMRMILMFDMPVETAEERKAYRKFRKFLMNEGFIMHQFSVYSKLLLNNSANNAMLERLKVNNPKKGSITLLTVTEKQFSRMIYLNGERDTSIANSDARLVFLGEDFTDEN
>LR134283.1|VED97342.1|231570_232437_+|CRISPR-associated-protein-Cas1
MGWRTVVVNTHSKLSYKNNHLIFKDASRTELIHLSEVDILLLETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSNQITWSEDVKAEVWTTIIAQKILNQAMYLGDCGFFEKSQSVIDLYNGLELFDPSNREGHAARIYFNTLFGNDFSREQDNDINAALDYGYTLILSMFAREVVVCGCMTQFGLKHANQFNQFNLASDIMEPFRPIIDRIVYENRNDDFVKIKRELFTIFSDTFLYNGKEMYLSNIISDYTKKVIKTLNQMGKGVPEFRI
>LR134283.1|VED97341.1|227380_231571_+|CRISPR-associated-protein,-SAG0894-family
MTKPYSIGLDIGTNSVGWAVITDDYKVPAKKMKVLGNTNRDYIKKNLLGALLFDGGETAEGRRLKRTARRRYTRRKNRLRYLQEIFAEEMMQVDESFFQRLDDSFLVEEDKQGSKYPIFGTLKEEKEYHKKFKTIYHLREELANSKEKADLRLVYLALAHMIKFRGHFLYEGDLKAENTDVQALFKDFVEEYDKTIEESHLSEITVDALSILTEKVSKSSRLENLIAHYPTEKKNTLFGNLIALSLGLQANFKTNFQLSEDAKLQFSKDTYEEDLEGLLGEVGDEYADLFVSAKNLYDAILLSGILTVDDNSTKAPLSASMVKRYKEHKEELAAFKRFIKEKLPKKYEEIFKDDTKNGYAGYVGADKKLRKRSGKLATEEEFYKYVKGILNKVEGADYFLDKIDREDFLRKQRTFDNGSIPHQIHLQEMHAILRRQGEHYPFLKENQDKIEKILTFRIPYYVGPLARKGSRFAWAEYKADEKITPWNFDDILDKEKSAEKFITRMTLNDLYLPEEKVLPKHSPLYETFTVYNELTKVKYVNEQGEAKFFDTNMKQEIFDHVFKENRKVTKDKLLNYLNKEFEEFRIVNLTGLDKENKAFNASLGTYHDLRKILDKSFLDDKVNEKIIEDIIQTLTLFEDREMIRQRLQKYSDIFTTQQLKELERRHYTGWGRLSYKLINGIRNKENKKTILDYLIDDGYANRNFMQLINDDALSFKEEIARAQIIGDVDDIANVVHDLPGSPAIKKGILQSVKIVDELVKVMGHNPTNIIIEMARENQTTDKGRRNSQQRLKLLQDSLKNLDNPVNIKNVENQQLQNDRLFLYYIQNGKDMYTGETLDINNLSQYDIDHIIPQAFIKDNSLDNRVLTRSDKNRGKSDDVPSIEVVHEMKSFWSKLLSVKLITQRKFDNLTKAERGGLTENDKAGFIKRQLVETRQITKHVAQVLDARFNAKHDENKKVIRDVKIITLKSNLVSQFRKDFKFYKVREINDYHHAHDAYLNAVIGTALLKKYPKLASEFVYGEFKKYDVRKFIAKSDKEIGKATAKYFFYSNLMNFFKKEVKFADGTVVERPDIETSEDGEIAWNKQTDFKIVRKVLSYPQVNIVKKTEVQTHGLDRGKPRGLFNANPSPKPKPDSSENLVGIKRNLDPKKYGGYAGISNSYAVLVKAIIEKGVKKKETMVLEFQGISILDRITFEKDKRAFLLGKGYKDIKKIIELPKYSLFELKDGSRRMLASILSTNNKRGEIHKGNELFVPQKFTTLLYHAKRINNPINKDHIEYVKKHRDDFKELLNYVLEFNEKYVGATKNGERLKEAVADFDSKSNEEICTSFLGAVNSKNAGLFELTSLGSASDFEFLGVKIPRYRDYTPSSLLKDSILIHQSITGLYETRIDLSKLGED
>LR134283.1|VED97340.1|225769_227155_+|FeS-assembly-protein-SufB
MTKVRDYAFGFHDDVKPLFSTGKGLTEEVVREISEIKNEPQWMLDYRLRSLELFHKLPMPDFGPDLSGIRFDDIVYYQKLSGDRARSWDEVPDEIKKTFERLGIPEAERQFLSGTVAQYESEVVYHNMKEEFAKQGIIFTDTDTAVQEYPDLVKKYFGTVISNAEHKFSALNSAVWSGGTFIYVPKNVQCQVPVQTYFRINGENAGQFERSLIIVEEGGSIQYIEGCTAPTYTTNSLHAANVEIIVKKDAFFRYTTIQNWSDNVYNLVTERGTVEEGGTLEWIDGNLGSKVNMKYPCSILNGRNARTSVLSMSFANYGQHLDAGCKVYHNAPKTSSTLISKSVAKDGGKTDYRGQVRFGKNSAGSKSHIECDTILMDGESSSDTIPFNEIHNSNVALEHEAKVSKVSEDQLYYLMSRGISEEEATAMIINGFMEPITKELPMEYAVELNQLINMSMEGSVG
>LR134283.1|VED97339.1|225192_225636_+|flavodoxin
MVLAKIVFASMTGNTEEIADIVADKLKELGLEVDIDECTTVDAEEFLEADIAIVASYTYGDGELPDEIVDFYEDLASLDLTGKIYGVVGSGDTFYDEFCKAVDDFDRAFAATGAEKGAENVKVDLSAEDEDIENLEKFAEALAEKVR
>LR134283.1|VED97338.1|224102_225041_-|DHH-subfamily-1-protein
MEIFKQILHKIKEYDTIIIHRHMRPDPDALGSQVGLKKLLQVNFPEKKIKVAGKTEPTLAWLAKMDDVSDDDYKHALVIVCDTANTARIDDERYNKGDFLIKIDHHPNDDIYGDISWVDTSSSSASELIALFALENKLKLDDYSAKLLYAGIVGDTGRFLYPATTARTMAVASKLREYPFDFAALARKMDSFSYQIAKLQGYVYDHLEVDENGAAHVILTQELLKANHLTDADTSAIVSAPGRIDSVELWGIFVEQENGNYRVRLRSKFIPINEVAKKHDGGGHPLASGANAYSKEEIEEVYQELKELAKRK
>LR134283.1|VED97337.1|223753_224023_-|50S-ribosomal-protein-L31
MAERKFLKMRKDIHPEYRPVVFMDTSTGYKFLSGSTKYSSETVQWEDGNTYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK
>LR134283.1|VED97336.1|223333_223624_+|Uncharacterised-protein
MKIYTINPTIDVVETPVEETSRIIRHLHLGEGKMIPEHKADVLVTVVCLEGKVDFTASGQTVQLVPGSFLTMEPNELHSLYGVKDSHVLVIQQLKY
>LR134283.1|VED97335.1|222609_223308_+|serine-type-D-Ala-D-Ala-carboxypeptidase
MKKRIGILLVASLFLLTACGGKKTNVETKQEGKATSAKVASSEPAKKKAKVHYNGSYYSVKGKYDEIVIANKHYPLSSDYNPGENPTAKAKLLELIAAMQREGYPISHQYSGFRSYQMQMTLYQNYVNQDGKEAADRYSARPGYSEHQTGLAFDLIGTDGNLVTEEKASQWLLKHAAEYGFVVRYLNGKEDKTGYMPEQWHLRYVGKEAKAIADSGLSLEEYYGFAGGDYKD
>LR134283.1|VED97345.1|235367_236009_+|Uncharacterised-protein
MLYMIGGSPCSGKSTIASLLTQQYGLLHIKLDDLTDQMMDQARANAKPISLLRQDRSPDQIWLRHPEEMAGEEWCFYEEIFPYVTSYLLNNQDKPLLLEGAGLLPHLVKSLEEPAVSYLCLTPTADFQTKHYRQREWVPYVLEDTSNPEQAFENWMQRDILFAQMVRKEAKKLGYPSLMTDGSRSEKETAEEIARLLKLPNTNKIDIKGENYD
>LR134283.1|VED97346.1|236001_237954_+|threonyl-tRNA-synthetase
MIKITFPDGAVREYESGSTTFDIAQSISNSLAKKALAGKFNGKLIDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPEIHLGVGPAIQDGFYYDTDNTAGQISNEDLPRIEEEMKKIVKENFPSIREEVTKDEAREIFKNDPYKLELIEEHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLNVAGAYWRGNSDNAMMQRIYGTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISPEVGQGLPFWLPDGATIRRIVERYITDREVNDGYQHVYTPPLASVDLYKTSGHWEHYQEDMFPPMDMGDGEQFVLRPMNCPHHIEVYKNHVHSYRELPIRIAELGMMHRFEKSGALSGLQRVREMTLNDSHLFVMPEQIQEEFKHVLDLMIDVYKDFNITDYRFRLSYRDPNDKHKYFDNDEMWENAQRMLKGAMDDLGLDYFEAEGEAAFYGPKLDVQVKTALGNEETLSTIQLDFLLPERFDLHYVGADGEEHRPVMIHRGIVSTMERFIAYLIETYKGAFPTWLAPHQVTVIPISNEAHADYAWKVAKELRNRGVRVDVDERNEKMQYKIRQSQTHKVPYQLIVGDKEQVDGTVNVRRYGSKQTHTETVAEFVNHILADIARKSRLDDREQ
>LR134283.1|VED97347.1|238118_238667_-|putative-transcriptional-regulator
MQNRQTATKQHIREALIQLLLEEKFETISVSKLCQRAGINRGTFYLHYLDKYDLIETLKEEIIAQLRKNFEETTNTRDLLIANLSYLQQNYDLIYAVSQSHYLNFRETIREFMLSILTNEQHRLQTEYFLKENFTISKKYALEVFLSSVEGIISLWISSGVKETPEEMTNTILETFDYDAWQ
>LR134283.1|VED97348.1|238803_239505_+|ABC-transporter,-ATP-binding-protein
MAYIEMKHSYKRYQMGDTEIIANNDISFDIEKGELVIILGASGAGKSTILNILGGMDSNDEGDVLIDGQNIAYYNAHQLTDYRRNDVGFVFQFYNLVPNLTALENVELASEIVQDAQDAAKALAAVGLGNRLHNFPAQLSGGEQQRVSIARAVAKNPKILLCDEPTGALDYKTGKQVLQILQDMSRKQGATVIIVTHNGALAPIADRVIRMHDARIQSVTLNEHPQDITSLEY
>LR134283.1|VED97349.1|239519_242885_+|ABC-superfamily-ATP-binding-cassette-transporter,-membrane-protein
MKKSILNKDIWLSFHQSKGRFLSIMFLMMLGSFALVGLKAASPDIENSANRYLSQMKMMDLAVMSDYGISKADQKELNTISNAHVEYGYFTDTVIGDSSTSVRVFSKTTNISKFKLVSGHFPSKENQVALASFYQGKYKIGDSITLNEEGTNDYALRQHTFTVTGFVNSSELASTISLGNSNSGSGTLSAYAVVTPKTFQSSVYTVARLRYDNLKTLNSFGDSYRKKIKQHENELEKLVADNGKNRLSEIKKQAQTKIAEGEAKIRTSQQVLADVRQQLRTAQDQIDQKRADLEAAQGQITEKESLLAQGAAQIAQAEQTLASSKAKLDTATAQLSSGWAQLNQMKTQLDQAASQLSAAKENVTNTQATLAIAQAELEKGQVQLAAAKVDLQKKMTALQAQGIDSATVPEIVAAQTQLAQEEAKLNLVRTELEQKQAEFQTGLSQYKSQEALYQAGLAQYQSAAEALNAKQAEYDAGLAQYQSGQATLRNKQAEYQAGQAQLAQAKQQIADGQAQLDQAQATLNDKKTEYEKQKKDAETKIKNGQADIQKAKEEVAGLSVPTYRVYTRRTFPGADEYTTTGNRAYGISAVGNAFPIVLYLVAALVTVTTMTRFVSEERTNAGVLKALGYRNQDVVKKFVVYGLVSSLLGTVMGSLLGTYFLPYILGKTIFKTSTYPALRLDFYWEISLIALVCSVLCGVVPALYIAHKELKEKPSQLLLPKAPTKGSKILLERIDFIWRRLSFTQKVTARNIFRYKQRMLMTIFGVAGSVALLFAGLGMSSSMEGMGNRQYGEIIKYDAVISQKQHLKSDEQAAINHLLADKKIAKKRGIYQETFTKKIKGAKDEQSLALFVTTGKDFHHFIELYDSQSKASLNLSSHGAVISQKLATIMHVSVGDTFDLKSDEGKLYKIKVSGITEMYAGHFIFMNQDYYQTVFARKFQENAYLIKLKDASSKNVQDTAASFMKLTGVRAVVQNTGILEQIDVIVKSLGFVMQILTVASILLAIVILYNLMNINVAERIRELSTIKVLGFHNKEVTLYIYRETILLSVIGIIVGLFLGNILHRSLLETIAPDAFLLNPTVSVFVYLVPVFSIIMILIVLGFMVNAILRRIDMLEALKSVD
>LR134283.1|VED97350.1|242976_243813_+|serine/threonine-protein-phosphatase
MKRKIALLSDIHGNTTALEAVLADAKKEQVTDYWFLGDLLAPGTGRKKILDLMAALPISLQVRGNWEDSIWNALHGKLDISRPSHLYMVCLCQYLLEEVTPEELNRLHELPLQLLIKVGDLEIAVTHHLPDKNWGRELIHIGQQENFDRLFEGNHCAIAIYGHIHQQFLRYATGGQMIINPGSIGQPFFLDACLRKDLRAQYAILKIDEQGLADVDFRRVAYDVNKELEMARILKLPYYEVYYESLVNGIHHTHNHDLLRAISEREDYVAHLKEFFKK
>LR134283.1|VED97351.1|243878_244316_+|putative-transcriptional-regulator
MQISSRFTIATHMLIVIALECQEHKVTSDFLADSVGVNPVIIRKTLSQLKSAGLISVARGRGGAIIRKDLKDITLLDVYQAVESLGKSGQLFSFHEHPNPSCPIGRNIHFVLDDKLAEIQATMEKELSKTSLADVVASAQEKIKK
>LR134283.1|VED97352.1|244359_245136_-|putative-glycyl-radical-enzyme-activating-protein
MSAEKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQKFKPEPMLDASSKKTITMGEEKSVEEIIKEVLKDREFYEESGGGLTLSGGEIFAQFEFAKAILKAAKEKGIHTAIETTAFVDHNKFVDLLQYVDFIYTDLKHYNTINHRKVTGVKNELIIKNIHYAFSQQKTIVLRIPVIPSFNDSLEDAEQFAILFKKLSIDQVQLLPFHQFGENKYKLLKRSYEMENVQALHPEDLYDYQQVFLDYEINCYF
>LR134283.1|VED97353.1|245268_246012_+|DeoR-family-transcriptional-regulator
MERLDEIVKLVSEFEKIDVNTLSDKLKVSKVTIRKDLDKLEMKGLLHREHGYAVLNSGDDLNVRLSFHYDTKRKIAQEAAKIVADNETIIIESGSTCALLAEEICRTKKNVKIITNSYFIADYVRKVDSCKIILLGGEFQNDSQVTVGPLLKEMIQFFHVEHAFVGTDGYDEELGFTGKDLMRSEVVQYMSEASDKMIVLTDSSKFDKRGTVKRFGLKQVSQVVTDQAIPTAAVQRLKAANIKLTLV
>LR134283.1|VED97354.1|246030_246993_+|transcriptional-regulator
MKSERKRLLAKIAYLYYIEEKSQAEIAAETGIYRTTVSRMLAEAKKEGIVKIEIEAFDARLFHLENVVKEKYGLKGLEIVANQVDDSPSDLEQRLAQSAAGMLRGMIDDNAKVGFSWGKSLSLLVEHSGSRHLNNVHFFPLAGGPSHIHARYHVNTLIYSMANKYHGDCRFMNATIIQEDEILAKGILSSKYFEDLKRSWQELDVVVVGIGGQVDEKNRQWLDMLTVEDFRTVENEGAVGEICCRFFDENGELVDEQLQNRTVAISLDYLKTVPNSLAFAYGRQKAAAILAVLRAGYVNHLVTDEATILKVLELDNIAVN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK449000	Streptococcus phage Javan64, complete genome	1208-1237	0	1.0
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MT900487	Streptococcus phage 23TH, complete genome	3686-3715	0	1.0
LR134283_1	1.15\|234482\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234482-234511	30	MK448842	Streptococcus phage Javan110, complete genome	7199-7228	0	1.0
LR134283_1	1.3\|233690\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233690-233719	30	MK448817	Streptococcus phage Javan59, complete genome	39658-39687	1	0.967
LR134283_1	1.3\|233690\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233690-233719	30	MK449000	Streptococcus phage Javan64, complete genome	40590-40619	2	0.933
LR134283_1	1.3\|233690\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233690-233719	30	MK449004	Streptococcus phage Javan68, complete genome	36252-36281	3	0.9
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	MK448816	Streptococcus phage Javan589, complete genome	11788-11817	4	0.867
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	MK448984	Streptococcus phage Javan562, complete genome	11788-11817	4	0.867
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	MK448987	Streptococcus phage Javan576, complete genome	10905-10934	4	0.867
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	MK448985	Streptococcus phage Javan566, complete genome	12964-12993	4	0.867
LR134283_1	1.7\|233954\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233954-233983	30	KM359505	Prochlorococcus phage P-TIM68, complete genome	55453-55482	4	0.867
LR134283_1	1.7\|233954\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233954-233983	30	HG796774	Uncultured bacterium plasmid pRGF00007	4804-4833	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KT337353	Streptococcus phage phiARI0460-2, partial genome	38063-38092	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KT337349	Streptococcus phage phiARI0399, partial genome	36537-36566	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KT337356	Streptococcus phage phiARI0468-2, complete genome	38203-38232	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065496	Streptococcus phage IPP60, complete genome	3602-3631	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065466	Streptococcus phage IPP25, complete genome	3765-3794	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065476	Streptococcus phage IPP36, complete genome	3865-3894	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065475	Streptococcus phage IPP35, complete genome	3466-3495	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065472	Streptococcus phage IPP31, complete genome	3602-3631	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065474	Streptococcus phage IPP34, complete genome	3604-3633	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065477	Streptococcus phage IPP37, partial genome	3466-3495	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065452	Streptococcus phage IPP10, complete genome	3602-3631	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065499	Streptococcus phage IPP63, complete genome	4677-4706	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065473	Streptococcus phage IPP32, complete genome	4627-4656	5	0.833
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065450	Streptococcus phage IPP8, complete genome	3604-3633	5	0.833
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448901	Streptococcus phage Javan306, complete genome	1259-1288	6	0.8
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448937	Streptococcus phage Javan436, complete genome	1252-1281	6	0.8
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448757	Streptococcus phage Javan427, complete genome	1252-1281	6	0.8
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448912	Streptococcus phage Javan340, complete genome	1252-1281	6	0.8
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	KY065449	Streptococcus phage IPP5, complete genome	1253-1282	6	0.8
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	NC_010945	Streptococcus phage PH15, complete genome	10491-10520	6	0.8
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	MH892351	Streptococcus phage SW6, complete genome	29729-29758	6	0.8
LR134283_1	1.6\|233888\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233888-233917	30	MH892375	Streptococcus phage SW30, complete genome	29914-29943	6	0.8
LR134283_1	1.7\|233954\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233954-233983	30	NZ_CP026693	Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' strain 5183 plasmid pNLP1, complete sequence	113386-113415	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448939	Streptococcus phage Javan440, complete genome	5784-5813	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448914	Streptococcus phage Javan348, complete genome	3523-3552	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448758	Streptococcus phage Javan433, complete genome	5784-5813	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448759	Streptococcus phage Javan439, complete genome	5784-5813	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448937	Streptococcus phage Javan436, complete genome	5031-5060	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448918	Streptococcus phage Javan366, complete genome	3511-3540	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448920	Streptococcus phage Javan372, complete genome	3373-3402	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MK448757	Streptococcus phage Javan427, complete genome	8193-8222	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	FR671406	Streptococcus phage 040922	35175-35204	6	0.8
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065451	Streptococcus phage IPP9, complete genome	4905-4934	6	0.8
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	AP014291	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S25-C40, * SEQUENCING IN PROGRESS *	21285-21314	6	0.8
LR134283_1	1.17\|234614\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234614-234643	30	NZ_CP035509	Haematobacter massiliensis strain OT1 plasmid pOT1-9, complete sequence	1337-1366	6	0.8
LR134283_1	1.18\|234680\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234680-234709	30	NC_017497	Lactococcus lactis subsp. cremoris A76 plasmid pQA504, complete sequence	2342-2371	6	0.8
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448939	Streptococcus phage Javan440, complete genome	1252-1281	7	0.767
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448758	Streptococcus phage Javan433, complete genome	1252-1281	7	0.767
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448759	Streptococcus phage Javan439, complete genome	1252-1281	7	0.767
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MK448910	Streptococcus phage Javan336, complete genome	1253-1282	7	0.767
LR134283_1	1.5\|233822\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233822-233851	30	NZ_CP029493	Escherichia coli strain HS30-1 plasmid pHS30-1, complete sequence	11938-11967	7	0.767
LR134283_1	1.5\|233822\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233822-233851	30	NZ_CP029688	Escherichia coli strain E706 plasmid pLKJULY7989, complete sequence	139930-139959	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KT337341	Streptococcus phage phiARI0131-1, complete genome	40848-40877	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KX578042	Leuconostoc phage Ln-7, complete genome	1751-1780	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	MN552147	Leuconostoc phage P974, complete genome	1646-1675	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KX578044	Leuconostoc phage CHA, complete genome	1657-1686	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065480	Streptococcus phage IPP40, complete genome	6332-6361	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065478	Streptococcus phage IPP38, complete genome	6330-6359	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KC013028	Leuconostoc phage phiLNTR2, complete genome	1646-1675	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	GQ451696	Leuconostoc phage 1-A4, complete genome	29467-29496	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KX578043	Leuconostoc phage CHB, complete genome	1657-1686	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KY065497	Streptococcus phage IPP61, complete genome	6332-6361	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KM262191	Leuconostoc phage Ln-8, complete genome	1751-1780	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KJ417497	Streptococcus phage Spn1, complete genome	6435-6464	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KC013027	Leuconostoc phage phiLN34, complete genome	1646-1675	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KC013029	Leuconostoc phage phiLNTR3, complete genome	1646-1675	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	MT682705	Escherichia phage vB_EcoS_SP8, complete genome	8963-8992	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	NC_042025	Salmonella phage SE1 (in:Nonagvirus), complete genome	8699-8728	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	MK165087	Escherichia phage BRET, complete genome	10772-10801	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	KP719132	Enterobacteria phage JenP1, complete genome	10775-10804	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	KJ419279	Enterobacteria phage 9g, complete genome	43663-43692	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	MK373794	Escherichia phage vB_EcoS_HdK1, complete genome	18990-19019	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	MK373795	Escherichia phage vB_EcoS_HdSG1, complete genome	18775-18804	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	NC_028997	Enterobacteria phage JenP2, complete genome	10774-10803	7	0.767
LR134283_1	1.10\|234152\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234152-234181	30	NC_029021	Enterobacteria phage JenK1, complete genome	10775-10804	7	0.767
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP031650	Pantoea agglomerans strain TH81 plasmid unnamed1, complete sequence	299149-299178	7	0.767
LR134283_1	1.13\|234350\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234350-234379	30	NZ_CP018638	Salmonella enterica subsp. enterica serovar Enteritidis strain 69-3861 plasmid pSE69-3861-1, complete sequence	9880-9909	7	0.767
LR134283_1	1.13\|234350\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234350-234379	30	NZ_MK758104	Escherichia coli strain 0126:B16 plasmid R16, complete sequence	27999-28028	7	0.767
LR134283_1	1.16\|234548\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234548-234577	30	NZ_LR135261	Enterococcus faecium isolate E4457 plasmid 4	45717-45746	7	0.767
LR134283_1	1.16\|234548\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234548-234577	30	NZ_LR135334	Enterococcus faecium isolate E7471 plasmid 4	14241-14270	7	0.767
LR134283_1	1.16\|234548\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234548-234577	30	NZ_CP014534	Enterococcus faecium strain E745 plasmid pl5, complete sequence	15824-15853	7	0.767
LR134283_1	1.18\|234680\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234680-234709	30	MK448663	Streptococcus satellite phage Javan98, complete genome	10233-10262	7	0.767
LR134283_1	1.22\|234945\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234945-234974	30	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	209324-209353	7	0.767
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	FR671407	Streptococcus phage 34117	32705-32734	8	0.733
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	NC_031929	Streptococcus phage phiARI0468-1, complete genome	36014-36043	8	0.733
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	FR671410	Streptococcus phage 8140	31622-31651	8	0.733
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	NC_024357	Streptococcus phage K13, complete sequence	34425-34454	8	0.733
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KT337364	Streptococcus phage phiARI0639b, partial genome	27471-27500	8	0.733
LR134283_1	1.9\|234086\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234086-234115	30	KC013026	Leuconostoc phage phiLN25, complete genome	1740-1769	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP046723	Pantoea agglomerans strain ASB05 plasmid pASB05p1, complete sequence	229828-229857	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP034470	Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_1, complete sequence	405306-405335	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	200353-200382	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP034475	Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_1, complete sequence	401442-401471	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP019166	Listeria monocytogenes strain HPB5415 plasmid pLM5578, complete sequence	30983-31012	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP023753	Listeria monocytogenes strain AT3E plasmid pLM58, complete sequence	47360-47389	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NC_013767	Listeria monocytogenes 08-5578 plasmid pLM5578, complete sequence	10008-10037	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP025569	Listeria monocytogenes strain PIR00540 plasmid pPIR00540, complete sequence	2674-2703	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP025444	Listeria monocytogenes strain MF4545 plasmid pMF4545, complete sequence	14387-14416	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NZ_CP025083	Listeria monocytogenes strain MF4626 plasmid pMF4626, complete sequence	47361-47390	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	AJ972879	Yersinia phage phiR1-37 complete genome	206452-206481	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	MN693807	Marine virus AFVG_250M375, complete genome	17426-17455	8	0.733
LR134283_1	1.12\|234284\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234284-234313	30	NC_016163	Yersinia phage phiR1-37, complete genome	206452-206481	8	0.733
LR134283_1	1.20\|234812\|31\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234812-234842	31	AP014020	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S27-C18, * SEQUENCING IN PROGRESS *	12316-12346	8	0.742
LR134283_1	1.20\|234812\|31\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234812-234842	31	AP014021	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S44-C26, * SEQUENCING IN PROGRESS *	10155-10185	8	0.742
LR134283_1	1.22\|234945\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234945-234974	30	NZ_CP021525	Acetobacter ascendens strain SRCM101447 plasmid pAP1447-1	159099-159128	8	0.733
LR134283_1	1.1\|233558\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233558-233587	30	MT349887	Acinetobacter phage 5W, complete genome	8304-8333	9	0.7
LR134283_1	1.7\|233954\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233954-233983	30	LC168164	Tenacibaculum phage pT24 DNA, complete genome	210528-210557	9	0.7
LR134283_1	1.7\|233954\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	233954-233983	30	FN667788	Campylobacter phage CP220, complete genome	99847-99876	9	0.7
LR134283_1	1.11\|234218\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234218-234247	30	NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	308944-308973	9	0.7
LR134283_1	1.21\|234879\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234879-234908	30	AY212251	Streptococcus virus C1, complete genome	14464-14493	9	0.7
LR134283_1	1.21\|234879\|30\|LR134283\|PILER-CR,CRISPRCasFinder,CRT	234879-234908	30	NC_004814	Streptococcus phage C1, complete genome	14464-14493	9	0.7

1. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK449000 (Streptococcus phage Javan64, complete genome) position: , mismatch: 0, identity: 1.0

tatactgttttaatcctcacactcaaagtt	CRISPR spacer
tatactgttttaatcctcacactcaaagtt	Protospacer
******************************

2. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MT900487 (Streptococcus phage 23TH, complete genome) position: , mismatch: 0, identity: 1.0

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tgctatctttctgctataataaaagcagaa	Protospacer
******************************

3. spacer 1.15|234482|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448842 (Streptococcus phage Javan110, complete genome) position: , mismatch: 0, identity: 1.0

gtcctagctcaaaatctctgaaactcctat	CRISPR spacer
gtcctagctcaaaatctctgaaactcctat	Protospacer
******************************

4. spacer 1.3|233690|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448817 (Streptococcus phage Javan59, complete genome) position: , mismatch: 1, identity: 0.967

ctcaaaatgtgtcttaccatacagcgcaat	CRISPR spacer
ctcaaaatgtgtcttaccatacagcacaat	Protospacer
*************************.****

5. spacer 1.3|233690|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK449000 (Streptococcus phage Javan64, complete genome) position: , mismatch: 2, identity: 0.933

ctcaaaatgtgtcttaccatacagcgcaat	CRISPR spacer
ctcaaaatgtgtcttatcatactgcgcaat	Protospacer
****************.***** *******

6. spacer 1.3|233690|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK449004 (Streptococcus phage Javan68, complete genome) position: , mismatch: 3, identity: 0.9

ctcaaaatgtgtcttaccatacagcgcaat	CRISPR spacer
ctcaaaatgtgtcttatcatacagcacagt	Protospacer
****************.********.**.*

7. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448816 (Streptococcus phage Javan589, complete genome) position: , mismatch: 4, identity: 0.867

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgatcaagaaagataggaggtgagcactat	Protospacer
**** *******************.*..**

8. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448984 (Streptococcus phage Javan562, complete genome) position: , mismatch: 4, identity: 0.867

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgatcaagaaagataggaggtgagcactat	Protospacer
**** *******************.*..**

9. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448987 (Streptococcus phage Javan576, complete genome) position: , mismatch: 4, identity: 0.867

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgatcaagaaagataggaggtgagcactat	Protospacer
**** *******************.*..**

10. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448985 (Streptococcus phage Javan566, complete genome) position: , mismatch: 4, identity: 0.867

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgatcaagaaagataggaggtgagcactat	Protospacer
**** *******************.*..**

11. spacer 1.7|233954|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 4, identity: 0.867

gcttcta-ctaattgttcattcaaagcgtca	CRISPR spacer
-tttctatctaattgttcatacaaagcatca	Protospacer
 .***** ************ ******.***

12. spacer 1.7|233954|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to HG796774 (Uncultured bacterium plasmid pRGF00007) position: , mismatch: 5, identity: 0.833

gcttctactaattgttcattcaaagcgtca	CRISPR spacer
gcttctgctacttgttcattcaaagcctgc	Protospacer
******.*** *************** *

13. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KT337353 (Streptococcus phage phiARI0460-2, partial genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

14. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KT337349 (Streptococcus phage phiARI0399, partial genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

15. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KT337356 (Streptococcus phage phiARI0468-2, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

16. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065496 (Streptococcus phage IPP60, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

17. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065466 (Streptococcus phage IPP25, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

18. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065476 (Streptococcus phage IPP36, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

19. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065475 (Streptococcus phage IPP35, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

20. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065472 (Streptococcus phage IPP31, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

21. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065474 (Streptococcus phage IPP34, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

22. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065477 (Streptococcus phage IPP37, partial genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

23. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065452 (Streptococcus phage IPP10, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

24. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065499 (Streptococcus phage IPP63, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

25. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065473 (Streptococcus phage IPP32, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

26. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065450 (Streptococcus phage IPP8, complete genome) position: , mismatch: 5, identity: 0.833

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tcttctttttctgctataatataagcagaa	Protospacer
* .* *.************** ********

27. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448901 (Streptococcus phage Javan306, complete genome) position: , mismatch: 6, identity: 0.8

-tatactgttttaatcctcacactcaaagtt	CRISPR spacer
atggaaag-ttaaatcctcacactcaaagtt	Protospacer
 *. *  * ** *******************

28. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448937 (Streptococcus phage Javan436, complete genome) position: , mismatch: 6, identity: 0.8

-tatactgttttaatcctcacactcaaagtt	CRISPR spacer
atggaaag-ttaaatcctcacactcaaagtt	Protospacer
 *. *  * ** *******************

29. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448757 (Streptococcus phage Javan427, complete genome) position: , mismatch: 6, identity: 0.8

-tatactgttttaatcctcacactcaaagtt	CRISPR spacer
atggaaag-ttaaatcctcacactcaaagtt	Protospacer
 *. *  * ** *******************

30. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448912 (Streptococcus phage Javan340, complete genome) position: , mismatch: 6, identity: 0.8

-tatactgttttaatcctcacactcaaagtt	CRISPR spacer
atggaaag-ttaaatcctcacactcaaagtt	Protospacer
 *. *  * ** *******************

31. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065449 (Streptococcus phage IPP5, complete genome) position: , mismatch: 6, identity: 0.8

-tatactgttttaatcctcacactcaaagtt	CRISPR spacer
atggaaag-ttgaatcctcacactcaaagtt	Protospacer
 *. *  * ** *******************

32. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_010945 (Streptococcus phage PH15, complete genome) position: , mismatch: 6, identity: 0.8

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgattaaaaaagataggaggtgagagcaat	Protospacer
**** **.**************** .. **

33. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MH892351 (Streptococcus phage SW6, complete genome) position: , mismatch: 6, identity: 0.8

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgattaagaaagacaggaggtgataacaat	Protospacer
**** ********.*********  *. **

34. spacer 1.6|233888|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MH892375 (Streptococcus phage SW30, complete genome) position: , mismatch: 6, identity: 0.8

tgataaagaaagataggaggtgagtatcat	CRISPR spacer
tgattaagaaagacaggaggtgataacaat	Protospacer
**** ********.*********  *. **

35. spacer 1.7|233954|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026693 (Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' strain 5183 plasmid pNLP1, complete sequence) position: , mismatch: 6, identity: 0.8

gcttctactaattgttcattcaaagcgtca	CRISPR spacer
gcttttactaattgttctttcaagtcttct	Protospacer
****.************ *****. * **

36. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448939 (Streptococcus phage Javan440, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

37. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448914 (Streptococcus phage Javan348, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctaccctttctgctataataaaatcagaa	Protospacer
* .  .****************** *****

38. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448758 (Streptococcus phage Javan433, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

39. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448759 (Streptococcus phage Javan439, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

40. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448937 (Streptococcus phage Javan436, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

41. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448918 (Streptococcus phage Javan366, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

42. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448920 (Streptococcus phage Javan372, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

43. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448757 (Streptococcus phage Javan427, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
tctctcctttttgctataataaaagcagaa	Protospacer
* .. .****.*******************

44. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to FR671406 (Streptococcus phage 040922) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatataagcagaa	Protospacer
  ** ..************** ********

45. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065451 (Streptococcus phage IPP9, complete genome) position: , mismatch: 6, identity: 0.8

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatataagcagaa	Protospacer
  ** ..************** ********

46. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to AP014291 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S25-C40, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tatataaagttttgatttttcttcttcgtt	Protospacer
 * ****.******* *********** *.

47. spacer 1.17|234614|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035509 (Haematobacter massiliensis strain OT1 plasmid pOT1-9, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgttttgcgcccttggttgctg-atat	CRISPR spacer
gttctgtattgcgcccttggttgttgcgta-	Protospacer
 *.**** ***************.** .**

48. spacer 1.18|234680|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_017497 (Lactococcus lactis subsp. cremoris A76 plasmid pQA504, complete sequence) position: , mismatch: 6, identity: 0.8

cccaatattcgctttaaattgttctgtcat	CRISPR spacer
ccacatatccgctttaaattgttgtgtaaa	Protospacer
**  ****.************** *** *

49. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448939 (Streptococcus phage Javan440, complete genome) position: , mismatch: 7, identity: 0.767

tatactgt------tttaatcctcacactcaaagtt	CRISPR spacer
------gtggaaagttgaatcctcacactcaaagtt	Protospacer
      **      ** *******************

50. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448758 (Streptococcus phage Javan433, complete genome) position: , mismatch: 7, identity: 0.767

tatactgt------tttaatcctcacactcaaagtt	CRISPR spacer
------gtggaaagttgaatcctcacactcaaagtt	Protospacer
      **      ** *******************

51. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448759 (Streptococcus phage Javan439, complete genome) position: , mismatch: 7, identity: 0.767

tatactgt------tttaatcctcacactcaaagtt	CRISPR spacer
------gtggaaagttgaatcctcacactcaaagtt	Protospacer
      **      ** *******************

52. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448910 (Streptococcus phage Javan336, complete genome) position: , mismatch: 7, identity: 0.767

-tatactgttttaatcctcacactcaaagtt	CRISPR spacer
atggaaag-tttaatcctcacactcagagtc	Protospacer
 *. *  * *****************.***.

53. spacer 1.5|233822|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029493 (Escherichia coli strain HS30-1 plasmid pHS30-1, complete sequence) position: , mismatch: 7, identity: 0.767

acggcgagaccatgagtggtaagtcttatc	CRISPR spacer
gagaggtgcccatgagtggtaagtgttatc	Protospacer
. *. * * *************** *****

54. spacer 1.5|233822|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029688 (Escherichia coli strain E706 plasmid pLKJULY7989, complete sequence) position: , mismatch: 7, identity: 0.767

acggcgagaccatgagtggtaagtcttatc	CRISPR spacer
gagaggtgcccatgagtggtaagtgttatc	Protospacer
. *. * * *************** *****

55. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KT337341 (Streptococcus phage phiARI0131-1, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatgaaaccagaa	Protospacer
  ** ..*************.*** *****

56. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KX578042 (Leuconostoc phage Ln-7, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
acccaactttgtgctataatataagcagac	Protospacer
  *.* **** ********** *******

57. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MN552147 (Leuconostoc phage P974, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

58. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KX578044 (Leuconostoc phage CHA, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

59. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065480 (Streptococcus phage IPP40, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatgaaaccagaa	Protospacer
  ** ..*************.*** *****

60. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065478 (Streptococcus phage IPP38, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatgaaaccagaa	Protospacer
  ** ..*************.*** *****

61. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KC013028 (Leuconostoc phage phiLNTR2, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

62. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to GQ451696 (Leuconostoc phage 1-A4, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

63. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KX578043 (Leuconostoc phage CHB, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

64. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KY065497 (Streptococcus phage IPP61, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatgaaaccagaa	Protospacer
  ** ..*************.*** *****

65. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KM262191 (Leuconostoc phage Ln-8, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
acccaactttgtgctataatataagcagac	Protospacer
  *.* **** ********** *******

66. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KJ417497 (Streptococcus phage Spn1, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atctccttttctgctataatgaaaccagaa	Protospacer
  ** ..*************.*** *****

67. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KC013027 (Leuconostoc phage phiLN34, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

68. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KC013029 (Leuconostoc phage phiLNTR3, complete genome) position: , mismatch: 7, identity: 0.767

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcaaactttgtgctataatataagcagac	Protospacer
  * * **** ********** *******

69. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MT682705 (Escherichia phage vB_EcoS_SP8, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

70. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_042025 (Salmonella phage SE1 (in:Nonagvirus), complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

71. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK165087 (Escherichia phage BRET, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

72. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KP719132 (Enterobacteria phage JenP1, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

73. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KJ419279 (Enterobacteria phage 9g, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

74. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK373794 (Escherichia phage vB_EcoS_HdK1, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

75. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK373795 (Escherichia phage vB_EcoS_HdSG1, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

76. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_028997 (Enterobacteria phage JenP2, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

77. spacer 1.10|234152|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_029021 (Enterobacteria phage JenK1, complete genome) position: , mismatch: 7, identity: 0.767

attcttcttcaaagctcgacgaatgagctt	CRISPR spacer
attcttcttcgaagctccacgaagcaacca	Protospacer
**********.****** *****  *.*.

78. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031650 (Pantoea agglomerans strain TH81 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggttttaaaatttcttctgtcca	Protospacer
*************.** ******** ...

79. spacer 1.13|234350|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018638 (Salmonella enterica subsp. enterica serovar Enteritidis strain 69-3861 plasmid pSE69-3861-1, complete sequence) position: , mismatch: 7, identity: 0.767

aatttttagcccctccatttcctcgacaaa	CRISPR spacer
gatgcctagccgctccatttccttgacaag	Protospacer
.** ..***** ***********.*****.

80. spacer 1.13|234350|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK758104 (Escherichia coli strain 0126:B16 plasmid R16, complete sequence) position: , mismatch: 7, identity: 0.767

aatttttagcccctccatttcctcgacaaa	CRISPR spacer
gatgcctagccgctccatttccttgacaag	Protospacer
.** ..***** ***********.*****.

81. spacer 1.16|234548|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135261 (Enterococcus faecium isolate E4457 plasmid 4) position: , mismatch: 7, identity: 0.767

aatttttagcccccccatttcctcgacaat	CRISPR spacer
catttttaagccccccatttcctcctgcat	Protospacer
 *******. **************    **

82. spacer 1.16|234548|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135334 (Enterococcus faecium isolate E7471 plasmid 4) position: , mismatch: 7, identity: 0.767

aatttttagcccccccatttcctcgacaat	CRISPR spacer
catttttaagccccccatttcctcctgcat	Protospacer
 *******. **************    **

83. spacer 1.16|234548|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014534 (Enterococcus faecium strain E745 plasmid pl5, complete sequence) position: , mismatch: 7, identity: 0.767

aatttttagcccccccatttcctcgacaat	CRISPR spacer
catttttaagccccccatttcctcctgcat	Protospacer
 *******. **************    **

84. spacer 1.18|234680|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MK448663 (Streptococcus satellite phage Javan98, complete genome) position: , mismatch: 7, identity: 0.767

cccaatattcgctttaaattgttctgtcat	CRISPR spacer
cttgatattcgcttgaaattgttttgttaa	Protospacer
*...********** ********.***.*

85. spacer 1.22|234945|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

caatcagattattaaattcccctaatttgg	CRISPR spacer
taaaggaattattaaattagcctaatttgg	Protospacer
.**  ..***********  **********

86. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to FR671407 (Streptococcus phage 34117) position: , mismatch: 8, identity: 0.733

tgctatctttctgctataataaaagcagaa	CRISPR spacer
cctcgcaattctgctataataaaagcagaa	Protospacer
. ....  **********************

87. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_031929 (Streptococcus phage phiARI0468-1, complete genome) position: , mismatch: 8, identity: 0.733

tgctatctttctgctataataaaagcagaa	CRISPR spacer
cctcgcaattctgctataataaaagcagaa	Protospacer
. ....  **********************

88. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to FR671410 (Streptococcus phage 8140) position: , mismatch: 8, identity: 0.733

tgctatctttctgctataataaaagcagaa	CRISPR spacer
cctcgcaattctgctataataaaagcagaa	Protospacer
. ....  **********************

89. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_024357 (Streptococcus phage K13, complete sequence) position: , mismatch: 8, identity: 0.733

tgctatctttctgctataataaaagcagaa	CRISPR spacer
cctcgcaattctgctataataaaagcagaa	Protospacer
. ....  **********************

90. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KT337364 (Streptococcus phage phiARI0639b, partial genome) position: , mismatch: 8, identity: 0.733

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atccccttttctgctataatgaaaccagaa	Protospacer
  *. ..*************.*** *****

91. spacer 1.9|234086|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to KC013026 (Leuconostoc phage phiLN25, complete genome) position: , mismatch: 8, identity: 0.733

tgctatctttctgctataataaaagcagaa	CRISPR spacer
atcagactttgtgctataatataagcagac	Protospacer
  * . **** ********** *******

92. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046723 (Pantoea agglomerans strain ASB05 plasmid pASB05p1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggttttaaaatttcttcggtcca	Protospacer
*************.** *******  ...

93. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034470 (Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggttttaaaatttcttcggtcca	Protospacer
*************.** *******  ...

94. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034149 (Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggttttaaaatttcttcggtcca	Protospacer
*************.** *******  ...

95. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034475 (Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggttttaaaatttcttcggtcca	Protospacer
*************.** *******  ...

96. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019166 (Listeria monocytogenes strain HPB5415 plasmid pLM5578, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tttttgatctttagaattttcttcttcttc	Protospacer
    *.*  *** *****************

97. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023753 (Listeria monocytogenes strain AT3E plasmid pLM58, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tttttgatctttagaattttcttcttcttc	Protospacer
    *.*  *** *****************

98. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_013767 (Listeria monocytogenes 08-5578 plasmid pLM5578, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tttttgatctttagaattttcttcttcttc	Protospacer
    *.*  *** *****************

99. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025569 (Listeria monocytogenes strain PIR00540 plasmid pPIR00540, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tttttgatctttagaattttcttcttcttc	Protospacer
    *.*  *** *****************

100. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025444 (Listeria monocytogenes strain MF4545 plasmid pMF4545, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tttttgatctttagaattttcttcttcttc	Protospacer
    *.*  *** *****************

101. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025083 (Listeria monocytogenes strain MF4626 plasmid pMF4626, complete sequence) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
tttttgatctttagaattttcttcttcttc	Protospacer
    *.*  *** *****************

102. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to AJ972879 (Yersinia phage phiR1-37 complete genome) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggtttttaattttccattatctt	Protospacer
************* *******. .* ..*.

103. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MN693807 (Marine virus AFVG_250M375, complete genome) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
ataataagttttggaattttcttctgacat	Protospacer
* ****** *** ************  . .

104. spacer 1.12|234284|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_016163 (Yersinia phage phiR1-37, complete genome) position: , mismatch: 8, identity: 0.733

aaaataaggttttgaattttcttcttcttc	CRISPR spacer
aaaataaggtttttaattttccattatctt	Protospacer
************* *******. .* ..*.

105. spacer 1.20|234812|31|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to AP014020 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S27-C18, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.742

aagtcggcaagtgatgatgagttgcaaagaa	CRISPR spacer
gcgatgaaaagttctgatgagttgcaaagaa	Protospacer
. * .*. ****  *****************

106. spacer 1.20|234812|31|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to AP014021 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C109A-MedDCM-OCT-S44-C26, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.742

aagtcggcaagtgatgatgagttgcaaagaa	CRISPR spacer
gcgatgaaaagttctgatgagttgcaaagaa	Protospacer
. * .*. ****  *****************

107. spacer 1.22|234945|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021525 (Acetobacter ascendens strain SRCM101447 plasmid pAP1447-1) position: , mismatch: 8, identity: 0.733

caatcagattattaaattcccctaatttgg	CRISPR spacer
tagaaagattattatattcccctgatttca	Protospacer
.*.  ********* ********.**** .

108. spacer 1.1|233558|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to MT349887 (Acinetobacter phage 5W, complete genome) position: , mismatch: 9, identity: 0.7

tatactgttttaatcctcacactcaaagtt	CRISPR spacer
catactgttttaatccttacacgtgatcca	Protospacer
.****************.**** ..*  .

109. spacer 1.7|233954|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to LC168164 (Tenacibaculum phage pT24 DNA, complete genome) position: , mismatch: 9, identity: 0.7

gcttctactaattgttcattcaaagcgtca	CRISPR spacer
agaaaaactaaattttcattcaaagcgtct	Protospacer
.     ***** * ***************

110. spacer 1.7|233954|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to FN667788 (Campylobacter phage CP220, complete genome) position: , mismatch: 9, identity: 0.7

gcttctactaattgttcattcaaagcgtca	CRISPR spacer
atatctactaattgttcactcaaatcactt	Protospacer
.. ***************.***** *...

111. spacer 1.11|234218|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_008757 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence) position: , mismatch: 9, identity: 0.7

ttggcgggcgcgtttgtcaatcacttagat	CRISPR spacer
gctgccggcgcgtatgtcaatcacttctcc	Protospacer
 . ** ******* ************   .

112. spacer 1.21|234879|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to AY212251 (Streptococcus virus C1, complete genome) position: , mismatch: 9, identity: 0.7

taaaggaatgttgaaagaaccattttataa	CRISPR spacer
acgtaacatgttgaaagcaccattctataa	Protospacer
  . .. ********** ******.*****

113. spacer 1.21|234879|30|LR134283|PILER-CR,CRISPRCasFinder,CRT matches to NC_004814 (Streptococcus phage C1, complete genome) position: , mismatch: 9, identity: 0.7

taaaggaatgttgaaagaaccattttataa	CRISPR spacer
acgtaacatgttgaaagcaccattctataa	Protospacer
  . .. ********** ******.*****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

712173 : 719704

Streptococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED97809.1\|712173_713262_-	carbamoyl phosphate synthase small subunit	R4TGJ8	Halovirus	3.2e-58	36.7
VED97810.1\|713300_714224_-	aspartate carbamoyltransferase catalytic subunit	A7RB08	Paramecium_bursaria_Chlorella_virus	1.3e-25	30.7
VED97811.1\|714282_715551_-	uracil permease	Q9KX94	Enterobacteria_phage	2.0e-59	35.9
VED97812.1\|715555_716077_-	pyrimidine regulatory protein PyrR	NA	NA	NA	NA
VED97813.1\|716357_717269_-	cytoplasmic protein	Q7AWZ3	Streptococcus_phage	1.4e-115	71.3
VED97814.1\|717265_718243_-	transporter	A1IMD5	Streptococcus_phage	4.6e-157	83.7
VED97815.1\|718239_719130_-	glmZ(sRNA)-inactivating NTPase	A0A0R8VB27	Thermobifida_phage	1.0e-06	32.2
VED97816.1\|719281_719704_-	nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.3e-23	45.3

DBSCAN-SWA_2

735973 : 745333

Bacillus_phage(42.86%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED97831.1\|735973_737722_-	putative multidrug ABC transporter permease/ATPase	W8CYL7	Bacillus_phage	3.5e-51	29.6
VED97832.1\|737702_739448_-	putative ATP-binding/permease protein	A0A076FI99	Aureococcus_anophage	1.8e-10	22.4
VED97833.1\|739620_740328_-	putative autolysin/N-acetylmuramidase	Q9ZXE4	Bacillus_phage	7.4e-16	42.3
VED97834.1\|740448_741036_-	putative ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
VED97835.1\|741047_742280_-\|protease	ATP-dependent Clp protease, ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.1e-131	57.7
VED97836.1\|742318_742492_-	membrane associated protein	NA	NA	NA	NA
VED97837.1\|742491_743004_-	dihydrofolate reductase	A0A1B2IAU3	Erwinia_phage	2.9e-22	34.8
VED97838.1\|743190_744030_-	thymidylate synthase	U5J9N5	Bacillus_phage	1.8e-85	56.1
VED97839.1\|744115_745333_-	putative permease, chloride channel	A0A1X9I5Z9	Streptococcus_phage	3.5e-98	52.6

DBSCAN-SWA_3

1029869 : 1038665

Streptococcus_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED98097.1\|1029869_1030697_+	putative exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	3.2e-119	75.5
VED98098.1\|1030722_1031346_-	putative endonuclease III	NA	NA	NA	NA
VED98099.1\|1031669_1032023_-	arsenate reductase	M1PLC0	Streptococcus_phage	3.2e-36	65.0
VED98100.1\|1032042_1032549_-	methylated DNA-protein cysteine methyltransferase	M1PFU9	Streptococcus_phage	9.9e-55	64.0
VED98101.1\|1032551_1033418_-	tetrapyrrole methylase family protein	M1PLC5	Streptococcus_phage	1.5e-111	73.6
VED98102.1\|1033420_1033738_-	initiation-control protein	M1PFV3	Streptococcus_phage	8.1e-31	62.9
VED98103.1\|1033772_1034666_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.5e-82	56.5
VED98104.1\|1034662_1035301_-	thymidylate kinase	M1PSC7	Streptococcus_phage	1.2e-73	64.7
VED98105.1\|1035455_1036319_+	YitT family protein	M1Q1P6	Streptococcus_phage	2.4e-93	57.5
VED98106.1\|1036387_1037044_-	putative acetoin utilization protein AcuB	M1NSC5	Streptococcus_phage	3.5e-84	72.2
VED98107.1\|1037190_1037901_-	branched-chain amino acid transport protein	G9BWD6	Planktothrix_phage	3.2e-19	28.9
VED98108.1\|1037900_1038665_-	putative branched-chain amino acid transport protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-16	26.1

DBSCAN-SWA_4

1141242 : 1149135

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED98203.1\|1141242_1142154_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.9e-90	54.4
VED98204.1\|1142216_1142441_-	amino acid transporter, AAT family	NA	NA	NA	NA
VED98205.1\|1142549_1143293_-	ABC transport system, ATP-binding protein	G3M9Y6	Bacillus_virus	1.8e-25	34.3
VED98206.1\|1143292_1144102_-	inner membrane amino-acid ABC transporter permease protein	NA	NA	NA	NA
VED98207.1\|1144261_1145605_-	ATP-dependent RNA helicase	E3T5E1	Cafeteria_roenbergensis_virus	2.4e-47	31.1
VED98208.1\|1145762_1147004_+	penicillin-binding protein 3	B6DZZ7	Stx2-converting_phage	1.4e-14	23.4
VED98209.1\|1147460_1147916_-	SUF system FeS assembly protein	A0A2H4N7M4	Lake_Baikal_phage	3.7e-08	27.7
VED98210.1\|1147902_1149135_-	cysteine desulfurase, SufS subfamily	Q2XUY6	environmental_halophage	1.0e-105	45.8

DBSCAN-SWA_5

1511261 : 1520109

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED98530.1\|1511261_1512743_+	inosine-5-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	9.5e-98	41.3
VED98531.1\|1512831_1513929_-	DNA replication and repair protein	NA	NA	NA	NA
VED98532.1\|1513930_1514308_-	Uncharacterized conserved protein	A0A1X9I5V8	Streptococcus_phage	1.2e-20	65.3
VED98533.1\|1514483_1515731_+	putative zinc-dependent peptidase	A0A1X9I714	Streptococcus_phage	9.7e-112	50.2
VED98534.1\|1515730_1517026_+	putative zinc-dependent peptidase	G3MBJ8	Bacillus_virus	2.3e-15	26.1
VED98535.1\|1517084_1517906_+	XRE family transcriptional regulator	NA	NA	NA	NA
VED98536.1\|1517916_1518456_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
VED98537.1\|1518406_1519285_+	cobalt import ATP-binding protein	G3M9Y6	Bacillus_virus	2.6e-18	30.5
VED98538.1\|1519269_1520109_+	cobalt import ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.7e-15	24.9

DBSCAN-SWA_6

1775306 : 1829163

Bacillus_phage(21.43%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VED98800.1\|1775306_1777436_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpL	K4FB40	Cronobacter_phage	1.7e-119	41.2
VED98801.1\|1777602_1779060_+	putative sugar-specific permease, SgaT/UlaA	NA	NA	NA	NA
VED98802.1\|1779090_1779372_+	putative phosphotransferase system sugar-specific EII component	NA	NA	NA	NA
VED98803.1\|1779558_1780044_+	putative phosphotransferase system sugar-specific EII component	NA	NA	NA	NA
VED98804.1\|1780091_1780757_+	putative 3-keto-L-gulonate-6-phosphate decarboxylase	NA	NA	NA	NA
VED98805.1\|1780760_1781621_+	L-xylulose 5-phosphate 3-epimerase	NA	NA	NA	NA
VED98806.1\|1781623_1782325_+	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
VED98807.1\|1782521_1784192_+	phosphotransferase	NA	NA	NA	NA
VED98808.1\|1784353_1785445_+	putative L-ascorbate 6-phosphate lactonase	NA	NA	NA	NA
VED98809.1\|1785555_1787532_+	putative transketolase	NA	NA	NA	NA
VED98810.1\|1787627_1788116_+\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
VED98811.1\|1788218_1788557_+	preprotein translocase subunit YajC	NA	NA	NA	NA
VED98812.1\|1788901_1789651_+	undecaprenyl pyrophosphate synthetase	R9W0U9	Flavobacterium_phage	1.3e-23	43.2
VED98813.1\|1789659_1790463_+	putative phosphatidate cytidylyltransferase	NA	NA	NA	NA
VED98814.1\|1790899_1792171_+\|protease	putative membrane-associated zinc metalloprotease	NA	NA	NA	NA
VED98815.1\|1792208_1794068_+\|tRNA	prolyl-tRNA synthetase	NA	NA	NA	NA
VED98816.1\|1794331_1794970_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
VED98817.1\|1795035_1796340_+	putative dihydrofolate synthase	NA	NA	NA	NA
VED98818.1\|1796517_1797078_+	membrane protein	NA	NA	NA	NA
VED98819.1\|1797140_1798205_-	glutamyl-aminopeptidase	NA	NA	NA	NA
VED98820.1\|1798324_1798612_+	Uncharacterised protein	NA	NA	NA	NA
VED98821.1\|1798608_1798926_+	thioredoxin family protein	A0A0K2FIM3	Achromobacter_phage	2.8e-07	37.8
VED98822.1\|1798942_1799569_+\|tRNA	tRNA-binding domain-containing protein	NA	NA	NA	NA
VED98823.1\|1799649_1800045_+	single-stranded DNA-binding protein	A1EAD1	Streptococcus_phage	1.0e-27	47.0
VED98824.1\|1800337_1801324_+	putative periplasmic sugar-binding protein	NA	NA	NA	NA
VED98825.1\|1801323_1802637_+	histidine kinase	NA	NA	NA	NA
VED98826.1\|1802629_1803313_+	putative two-component response transcriptional regulator	NA	NA	NA	NA
VED98827.1\|1803336_1804596_+	putative sugar-binding periplasmic protein	NA	NA	NA	NA
VED98828.1\|1804792_1805227_+	PTS system, sugar-specific IIA component	NA	NA	NA	NA
VED98829.1\|1805250_1805745_+	PTS system, sugar-specific IIB component	NA	NA	NA	NA
VED98830.1\|1805780_1806632_+	phosphotransferase system, IIC component	NA	NA	NA	NA
VED98831.1\|1806633_1807464_+	PTS system mannose-specific transporter subunit IID	NA	NA	NA	NA
VED98832.1\|1807477_1807768_+	membrane protein	NA	NA	NA	NA
VED98833.1\|1807912_1808194_+	chaperonin Cpn10	NA	NA	NA	NA
VED98834.1\|1808225_1809848_+	chaperone GroEL	A0A219YK78	uncultured_virus	6.4e-156	56.6
VED98835.1\|1810569_1811337_+	hypothetical cytosolic protein	NA	NA	NA	NA
VED98836.1\|1811523_1812162_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	1.1e-42	42.5
VED98837.1\|1812226_1812886_+	putative hydrolase	A0A1D6Y7U0	Golden_Marseillevirus	6.0e-12	29.7
VED98838.1\|1812971_1813508_+\|transposase	transposase IS3/IS911 family protein	A0A1B1P776	Bacillus_phage	1.6e-07	31.1
VED98839.1\|1813612_1814323_+\|transposase	insertion sequence transposase	A0A1B1P773	Bacillus_phage	1.6e-55	51.5
VED98840.1\|1814401_1814917_-	acid-resistance membrane protein	NA	NA	NA	NA
VED98841.1\|1815485_1816757_-	recombination factor protein RarA	A0A127AWE7	Bacillus_phage	8.4e-95	45.4
VED98842.1\|1816858_1817329_+	Protein of uncharacterised function (DUF3013)	NA	NA	NA	NA
VED98843.1\|1817378_1817822_+	putative 7,8-dihydro-8-oxoguanine-triphosphatase	NA	NA	NA	NA
VED98844.1\|1817818_1818298_+	putative acetyltransferase	NA	NA	NA	NA
VED98845.1\|1818301_1819255_+	ribosomal protein L11 methyltransferase	NA	NA	NA	NA
VED98846.1\|1819255_1819996_+	RNA methyltransferase	NA	NA	NA	NA
VED98847.1\|1820162_1820309_+	Uncharacterised protein	NA	NA	NA	NA
VED98848.1\|1820482_1822699_+	GTP diphosphokinase	A0A1B1IUF0	uncultured_Mediterranean_phage	1.5e-09	32.6
VED98849.1\|1822787_1823231_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
VED98850.1\|1823210_1823309_-	Uncharacterised protein	NA	NA	NA	NA
VED98851.1\|1823353_1824001_-	putative transcriptional regulator	NA	NA	NA	NA
VED98852.1\|1824155_1825085_-	putative metal ABC transporter substrate-binding lipoprotein	NA	NA	NA	NA
VED98853.1\|1825119_1825968_-	ABC-type Mn2+/Zn2+ transport systems permease component	NA	NA	NA	NA
VED98854.1\|1825969_1826689_-	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.5e-19	29.0
VED98855.1\|1826865_1828761_+	putative endopeptidase O	A0A1V0SHG2	Klosneuvirus	1.9e-66	27.3
VED98856.1\|1828869_1829163_+\|transposase	ISSag7 transposase	A0A0N7GFG6	Staphylococcus_phage	1.5e-23	55.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage