CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134303	Shewanella putrefaciens strain NCTC12093 genome assembly, chromosome: 1	3 crisprs	DEDDh,DinG,WYL,RT,cas3,csa3,csx1,cas2,cas1,csx16,cas6,csm3gr7,csx10gr5,cas10	0	10	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134303_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134303_1

972053-972187

Orphan

Consensus_repeat	Method
AACAAAACCGGACACCCAACCTCAATAGCGCGGTAGCTAACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134303_1

>merge|LR134303|1|972053-972187|CRISPRCasFinder
AACAAAACCGGACACCCAACCTCAATAGCGCGGTAGCTAACCTCCGACTATGCTTTAGTTAAGCATTGAACAAGGAGGTTTGTATGCCGAGAACAAAACCGGACACCCAACCTCAATAGCGCGGTAGCTAACCTC

>LR134303|1|1|972053-972187|CRISPRCasFinder
AACAAAACCGGACACCCAACCTCAATAGCGCGGTAGCTAACCTC	CGACTATGCTTTAGTTAAGCATTGAACAAGGAGGTTTGTATGCCGAG
AACAAAACCGGACACCCAACCTCAATAGCGCGGTAGCTAACCTC

Protein	Signature genes	Signature genes Name	Protein_function
LR134303.1\|VEE61141.1\|977194_977371_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|271182
LR134303.1\|VEE61142.1\|977711_978746_+\|Transposase-and-inactivated-derivatives	unknown	unknown	unknown
LR134303.1\|VEE61137.1\|973561_974950_+\|RHS-repeat-associated-core-domain	unknown	unknown	gnl\|CDD\|274730
LR134303.1\|VEE61143.1\|979253_979622_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|274303
LR134303.1\|VEE61144.1\|979639_980596_-\|Glycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240639
LR134303.1\|VEE61134.1\|969078_971376_+\|Tetratricopeptide-repeat	unknown	unknown	unknown
LR134303.1\|VEE61126.1\|959188_960196_+\|Thiosulfate-binding-protein-precursor	unknown	unknown	gnl\|CDD\|226630
LR134303.1\|VEE61145.1\|980641_981286_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379226
LR134303.1\|VEE61131.1\|964493_966062_-\|ATP-dependent-zinc-metalloprotease-FtsH-3	unknown	unknown	gnl\|CDD\|177094
LR134303.1\|VEE61132.1\|966197_967373_+\|Phosphoribosylglycinamide-formyltransferase-2	unknown	unknown	gnl\|CDD\|236454
LR134303.1\|VEE61139.1\|976082_976796_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE61129.1\|962100_963231_+\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	unknown	unknown	gnl\|CDD\|224043
LR134303.1\|VEE61140.1\|976926_977073_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE61136.1\|972247_973225_+\|Transposase-and-inactivated-derivatives	unknown	unknown	unknown
LR134303.1\|VEE61138.1\|974970_975393_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE61133.1\|967574_969089_+\|Protein-of-uncharacterised-function-(DUF3142)	unknown	unknown	gnl\|CDD\|371478
LR134303.1\|VEE61135.1\|971561_972008_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE61128.1\|961234_962104_+\|Sulfate-transport-system-permease-protein-CysW	unknown	unknown	gnl\|CDD\|226665
LR134303.1\|VEE61130.1\|963802_964276_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE61127.1\|960379_961225_+\|Sulfate-transport-system-permease-protein-CysW	unknown	unknown	gnl\|CDD\|131194

Protein	Function_ID	Function_description	E-value
LR134303.1\|VEE61141.1\|977194_977371_-\|Uncharacterised-protein	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.30903e-08
LR134303.1\|VEE61143.1\|979253_979622_-\|Uncharacterised-protein	gnl\|CDD\|274303	TIGR02794, Protein_TolA, TolA protein. TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	4.29339e-07
LR134303.1\|VEE61144.1\|979639_980596_-\|Glycerate-dehydrogenase	gnl\|CDD\|240639	cd12162, 2-Hacid_dh_4, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	0
LR134303.1\|VEE61126.1\|959188_960196_+\|Thiosulfate-binding-protein-precursor	gnl\|CDD\|226630	COG4150, CysP, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	0
LR134303.1\|VEE61131.1\|964493_966062_-\|ATP-dependent-zinc-metalloprotease-FtsH-3	gnl\|CDD\|177094	CHL00195, ycf46, Ycf46; Provisional.	8.27098e-113
LR134303.1\|VEE61132.1\|966197_967373_+\|Phosphoribosylglycinamide-formyltransferase-2	gnl\|CDD\|236454	PRK09288, purT, formate-dependent phosphoribosylglycinamide formyltransferase.	0
LR134303.1\|VEE61129.1\|962100_963231_+\|Sulfate/thiosulfate-import-ATP-binding-protein-CysA	gnl\|CDD\|224043	COG1118, CysA, ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism].	4.66877e-162
LR134303.1\|VEE61145.1\|980641_981286_-\|Uncharacterised-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	3.16339e-10
LR134303.1\|VEE61133.1\|967574_969089_+\|Protein-of-uncharacterised-function-(DUF3142)	gnl\|CDD\|371478	pfam11340, DUF3142, Protein of unknown function (DUF3142). This bacterial family of proteins has no known function.	2.12779e-103
LR134303.1\|VEE61137.1\|973561_974950_+\|RHS-repeat-associated-core-domain	gnl\|CDD\|274730	TIGR03696, tRNA_nuclease_WapA, RHS repeat-associated core domain. This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.	1.20551e-12
LR134303.1\|VEE61128.1\|961234_962104_+\|Sulfate-transport-system-permease-protein-CysW	gnl\|CDD\|226665	COG4208, CysW, ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism].	8.262e-144
LR134303.1\|VEE61127.1\|960379_961225_+\|Sulfate-transport-system-permease-protein-CysW	gnl\|CDD\|131194	TIGR02139, permease_CysT, sulfate ABC transporter, permease protein CysT. This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions].	6.37627e-138

>LR134303.1|VEE61135.1|971561_972008_+|Uncharacterised-protein
MARKEKAESESYRKFIDEQAKLAYEELVKNQSPKKAFFGAILGVFLGLALLILFVWNGLVFYWMLFVPAAVIGYLACKFGKIYESKYANMIGVIGLLTNGFAVMTLYNYEAIALSTIPIAFIVTRYFAKLKLTEAQERAIWRKEIGKL
>LR134303.1|VEE61134.1|969078_971376_+|Tetratricopeptide-repeat
MRHKSNSLPAKAIPRWKTKLKQTSLIGLSLFSPVLLACGPDFPLQLTQDRQNNLSYLPQTSFSQQLSGLAKPLAWQFQGAPAAQEYLWDEAHSRYLSQTRAYENSELSEAQLAQVNSLRDAQSLAEAEQIAAQLKESLAPALTWYSLGAMAFDAKEYDKASDYFKKVIALPESERAGRSLWALYSLSRIELIKSKTASDNSHFVQANAYLQQLQTEVTQGAADPLRLSLAGLGEQAYILLHQGQAQIEVSRGEYEPPKIDVALNPATLDKVIELYATQSVQGDSSGYDSLLMLSRSLMSKNINELKPLLQQPSVQQLLIAYWQSSANDFAFDGQLMEMGQKVAEILTVFPTDGVVLSQGDKLAAIYYQLGDYASAERMLALAKPSGLTWWLTAKLMLQKGDQAQAAKAYAQAVRHFPTDMNATAATGSQQDAQQQAIEADAEQATYCRIRAEQGVLSLERGEYVDALGQLLASGDEYWQDIAYVAERVLTTAELKLFIDEHVPVMTFEYPKDSDWYDSVEPINNRLRYLLGRRLLREGAIAEAPVYFSNPTLNANVLEYGKALTAAKNSKGIESARAYWVAAELARHQGMEILGFELAPDYSIYAGMFDLRDWYAADKLSDKEQQRISASQAIPDKRFHYRYQAAELANRAADLVPHNSQAYAALLCQATGWVLYRDDELARRYYKKYVANGPFVPWAENFGTQCETPDFDRAVEREKANQIAEWNAMYHKLKKPVAYGSLVITAALIGFIGLRRRSRRAKNHQS
>LR134303.1|VEE61133.1|967574_969089_+|Protein-of-uncharacterised-function-(DUF3142)
MAQSTLGFYSYPMDLRSRYSTRFQPKHFESKHFEPRRSKSLQAIHRTLSLLFRLSQLLALSFGLVFLSACQPANQDTPSIKTATTAPRELTQEVYVWQRQWRDANQSALVESQSTFNGVRILALQAHPKPNGADIWFEVQVNHTWLQADPRPKVAVIRLDGQLTRLNNREALQKILALIQDWQAKGTRLAGIEIDHDSASSKLAAYNAFLRELKSQLPHSLKLSITSLPAWMSSSEFPALFDNIDELVLQIHSVSDPRLGLFDATQGWQWVEQLSRLAKVPYLIALPSYGSAVYSTAAGYRVESEVPMQMPLADTASSQHLARQELMADPLVLQSFVKKLHTFADTKLKGIIWFRLPLEGDKRVWPLSTLIAVAKQQPLAAHIELEILSQANTGSAQHEAPGSRLFQLVLVNKGNLAGKLPGQLSLAAQACSGYDAQNGYQAKLTQGILVWQLPQATSTERAAAPASSQFAPNLISAIELSPNGRRVIGWARCESLHLQGIYAP
>LR134303.1|VEE61132.1|966197_967373_+|Phosphoribosylglycinamide-formyltransferase-2
MIGTPYTEGARRAMLLGCGELGKEVAIELQRLGVEVIGVDRYPNAPAMQIAHRSHVINMLDAKALRAVIELEKPHLVIPEIEAIATQTLVEMEAEGLNVVPTARATKLTMDREGIRRLAAETLGLPTSPYFFCDTETEFNQAISKIGVPCVVKPVMSSSGKGQSVIRDTAQSAKAWQYAQEGGRAGGGRVIVEGFIPFDYEITLLTISAVNGIHFCAPIGHRQEDGDYRESWQPQAMSADVLAKSQAIASKVVEALGGYGLFGVELFVKGSDVYFSEVSPRPHDTGLVTLISQDLSEFALHVRAILGLPIPNIHQHGPSASAVVLVEGKSKNIRYQGLADALAAENTQLRLFAKPEIDGRRRLGVALARDKDIESAVNKALDSASKVKVIF
>LR134303.1|VEE61131.1|964493_966062_-|ATP-dependent-zinc-metalloprotease-FtsH-3
MLGIVKILFVAVFYVNFSIHNGLWKPKMQDIRDLTSVLRSKTPIVVIETYEEYRVVDMLKRVANVLYQPLFTWSITQGLTRVDKPMAAQKFNTEPGDILGQIKSTTQQGIYVLCDFHPFVIDAPKNVRLLKEIALEYDALQHTLVLVSHAFEIPPEIKRYCAYFQLTLPSTSQLENLIYLEVDKVRGQGMPLTVDDKAVVKLAENLRGVTLDDARRLIHKAIVDDGAITHSDVDLINKAKFQLLDLNGILQFEYDTSDFSQIAGLHNLKKWLKQRAPVTQATTDAKATVQPDTPKGVLLLGVQGSGKSLAAKAVAGVWQRPLLRLDMGALYNKYIGETEKNLRNALELADMMSPCILWIDEIEKGLSGSSSDEGTSTRILGTLLTWMAERKSEVFVVATANDIQALPPELMRKGRMDEIFFVDLPDEAIRQAIFLIHCQRRGIDVTRLDLAQLSRHSQGFSGAEIEQAVIAAMYSARSLGRSLDQGMLLEELTKTKPLSIVMGDKINALRQWAAGRTVNAHE
>LR134303.1|VEE61130.1|963802_964276_-|Uncharacterised-protein
MISREEMSFEQEFTEKVGGYLDNLTDELQPILKQLIEHDYPQEVVTLAFEVFADSFSSQFPVRVFFMDIDGKATYASPVNPYLLDIDHVYPDEFEEKYIENDEDLDPWQIATNALIEWFSKCWIAAGGQHFKLKANIAPHDSHYEFNLVECQWQERC
>LR134303.1|VEE61129.1|962100_963231_+|Sulfate/thiosulfate-import-ATP-binding-protein-CysA
MSIRLTNISKKFGQFQALSPLNLDIQEGEMIGLLGPSGSGKTTLLRIIAGLEGADSGQIHFGNRDVTQVHVRDRRVGFVFQNYALFRHMTVADNVAFGLEVIPKNQRPSKAEIQKRVSHLLEMVQLGHLAQRYPEQLSGGQKQRIALARALATQPEVLLLDEPFGALDAKVRKELRRWLRSLHDELKFTSVFVTHDQDEALELSDRVVVMSNGHIEQVNTPIELYAQPNSRFVFDFLGNVNRFEASWQQNRWTNGDAFLVPPEQAPLQQNGALYVRSHELALADKPNSQAHIPFTIVAITPVGAEVRVELAPIGWQSEELWEATFTHHHLQELGLQKGSVVYATPRTAYFFGEQGDGSPIRQNWPFLPPGSLAFDI
>LR134303.1|VEE61128.1|961234_962104_+|Sulfate-transport-system-permease-protein-CysW
MNSFKPLRVGEAPLIKWSLITLAVFLAMVLLLLPLVSIFQQAFVGGWERYIKHLSQPDSLHAIGLTLMVAALTVPINLVFGVLLAWSVTRFEFPGRKLLITLIDIPFAVSPVVAGLLYLLLYGNSGWLGAWLFEHDLQIMFAWPGILLVTIFVTCPFVARELIPLMQQQGASEEEAAVILGASWWQLFRRVTLPNIKWALIYGVILTNARAVGEFGAVAVVSGNIRGETNTLPLHVQLLYEDYQAEAAFASASLLALIALCTLLLKALVEWRQQRSLSANDNQEQSQSL
>LR134303.1|VEE61127.1|960379_961225_+|Sulfate-transport-system-permease-protein-CysW
MIFNNGRLRHKRVLPGFSISLGVSLLFVSLILLLPTTGLIMQTSQMSWAEYWGVIADPRVLASYKVTILSALVASLFNCLFGLLLAWVLVRYEFPGKRILDALVDLPFALPTAVAGITLATLYAENGQIGSLLAEIGIKVAYTPLGIVVAMIFTSIPFVVRTVQPVLEELSHDEEEAGMTLGATDGAVFWRVILPSLWPALVVGTALSFTRSLGEFGAVIFIAGNMPYISEITSLMIFVRLQEFDFAGASAIASVVLLTSLLLLLLINLWQARYLRRIHGR
>LR134303.1|VEE61126.1|959188_960196_+|Thiosulfate-binding-protein-precursor
MPVKLTKALLGTLLLGTTLNVAAADQTLLNSSYDIARELFNAYNPVFAKHWQEQTGKTVEIKQSHAGSSAQARSILQGLPADVVTFNQVTDVQILHDRGKLIPENWQQLLPNASSPYYSTIAFLVRKGNPKQISDWNDLAKDDVKLVFPNPKTSGNARYTYLAALGYAQKNYGKDNQVSLDEFLKKFLGNVAVFDTGGRGATTSFVERGIGDVLITFESEVNNIRQQYGADDYQVVVPKTSILAEFPVAVVEKNAKRNGTQELATEYLNYLYSEEAQRLLAGFNYRVHNEKVVAEFTKQFPAVELMTVEQIIGNWDNAMKTQFANGAKLDQLLKR
>LR134303.1|VEE61136.1|972247_973225_+|Transposase-and-inactivated-derivatives
MPRPRRTQISLEDTPYYHCCSRVVRRAFLCGDDTYSGKNYDHRRAWVESLLFELEAVFAIDIAAFAVMSNHLHVVLRVDIETANRWTDREVLEQWHKLFKGDELTQKFVKGELVEAHQVNRLKHSIALYRSRLCDISWFMRCLNEPIARQANQEDNCTGRFWEGRFKSQALLDEAAVLACMTYVDLNPIRAQLADTPEQSDHTSIQLRIRAALKGEQPSNLLPFIGNECDNRPNGIAFSLKDYLQLVDDTGRIIRNDKRGYISESSAKILNRLNITHDNWLKLTTEFGKLFHGPVGTLQELTDYCEHLEKRRRHFATSCQHFNSN
>LR134303.1|VEE61137.1|973561_974950_+|RHS-repeat-associated-core-domain
MHYVIDLKWVARFTSFVYGSDNMRAKQSRTVDSATTTTYYVDKYYEADSDGSWRAYLDDIAVLSYTSQRGHLLQFTLKDRLGSATTLADQNGNIVSQRYFDPFGRTASTGGGHGTDIVNKNTLQSKLQDLDITNKNRRGFTDHEHLNEQQLIHMNGRIYDYNLGRFMSVDPFIQSPTSTQSVNPYSYIMNNPLAGIDPTGYLAECPDRNEGCPKPEEEKPEKKRRMDGSGRGSGWTVIYDRSSNGSSRQSSSATGTQKTEAIGSPKQNANKQYPSYGNDANFAKGYGSLKGDMSGILSMTGPALAVDAVKAGIEIANEIADEYEQSGLSMSTFIVAGKAAGEAAIDVGAKKLRLPDVVTGGPHGKIKGISGHESHHMPADSVSPIAKDKGPAISMEKGDHRQTASWGNSREARAYRSQQAQLIQRGDFKGAQQMDINDVRSKFGEKYDKAINQMLDYSKTLD
>LR134303.1|VEE61138.1|974970_975393_+|Uncharacterised-protein
MDFSIIPFEGVGSIKFGMTPKQVRTNLGSGFKSFKRTPDSVLPCDYYEALGVFIYYKLPSVVEAIEFAEPANPELDKAGLLTMSFNEVHNFLAAKDPSLEIQSDSLTSYNLGISVYAPNADEDPNLLIESILLFENGYYD
>LR134303.1|VEE61139.1|976082_976796_-|Uncharacterised-protein
MLKMVIGIFIALFAAFLFFLNYNDNAIVTADKYEAAPVSTSSIIHKEEKVEVSLKNDEVSLEKVEALVSVPEKKSVEEKSKVDSIEQNDEAFFSQFTRLTKNDFQTPMMLTSAFLNENGNVSKAALEDAFNASDFNELIHVINSIDKTENGTARENLLSERLYKLDNLQVHSETYSCSGKICLVSFDFEGDESSATELSNFTKNYSFTNIVDGDNGFKKFKAIYIQTDDPSTLTLSY
>LR134303.1|VEE61140.1|976926_977073_+|Uncharacterised-protein
MEPEEQLQVIEYTVAELRTAIEVTKPSKTFFIICPYIQVCQIILARLT
>LR134303.1|VEE61141.1|977194_977371_-|Uncharacterised-protein
MLPHVTEKMLGHLLGGVMAVYNKHDWLEEQAEAYEQWTSKIKLAALGDGSVVVLERRA
>LR134303.1|VEE61142.1|977711_978746_+|Transposase-and-inactivated-derivatives
MTSARRQLIDANATPFYHVINRCVRRAFLCGEDKLSGRSYEHRRGWIVDKIKALSAIFCIDICAYAVMSNHYHLVLKIDVDKAKSLTQKDIISRWCQITKGHAIATKYMNDDALIEGERMLLDGLITEWHERLSSISWFMRCLNEEIARKANREDECKGAFWEGRFKSQALLDEQALLACMMYVDLNPIRAGIADSLQSSDFTSIQERINSLNTPNHPLTIPVSQTDSATNQAHILRKSLVQFDGAAHLNQQVGIPFHFADYLELIDWTGRAIRLDKKGYIDNQRPKLLNELGIAPDAWLTSAKEFRRQYSGISGRWDSMCAFKKQHNSGKWCKGKASSQALHP
>LR134303.1|VEE61143.1|979253_979622_-|Uncharacterised-protein
MYRTLLVCMLGFALNGCAHQIRVPSSCQTVNECAELIKLKIQSNLEFDESFKDQTVKVNFHLDQSANVISYKMLEPSKVIKLNEAVKSAVLTSSPFTEVLSADSEVFSEIKEVNLIVIPRLD
>LR134303.1|VEE61144.1|979639_980596_-|Glycerate-dehydrogenase
MKIVVLDGETLNPGDLTWQAVSALGEFSCFARTPSAEIIPRAQDAEIVLTNKTPLDANTLAQLPKLKYIGVLATGTNVVDLAVAKELGIVVTNVPAYGPDAVAQMVFAHILHHTQAVAAHHQAVAAGQWSNCSDFCFTLMPLQSLKGKTLGLIGYGDIGQQVAKLALAFGMKVLVNTRTEPSDLPQGVSWTSRDTVFKESDILSLHCPLTPETTELINAQTLELMKPQALLINTARGGLIDEAALAAALTQGKVFAGVDVLSTEPPSADNPLLTAPNITISPHNAWATKEARQNLFNIATANLKSFLQGNIRNCVNSK
>LR134303.1|VEE61145.1|980641_981286_-|Uncharacterised-protein
MKYVNRLTVIAGLLPLTLTLPTYAEPELFVAPYGGYSFGGSSFDINELDANKAETDNKQSVGIEEASHYGIMLGIGTNDPGNIYLLYSRQSSELKSGGLFTPDLVASLDVDYIHLGGTLFFPRGDFQPYITASAGVTRMMPDDWSTETRFSMGIGGGAEYRMTQNFALFADLRGYATFIDSDSSLFCNEDQCLWHVTSDVMWQVQANIGVKLSF

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Crispr_ID: LR134303_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134303_3

4614027-4616302

TypeIII-A

Consensus_repeat	Method
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CRISPRCasFinder
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CRT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	PILER-CR

32 spacers

csx1,cas2,cas1,DinG,csx16

The CRISPR arrays of LR134303_3

>merge|LR134303|3|4614027-4616302|CRISPRCasFinder,CRT,PILER-CR
GTCTAAGTCCCTTTAAATGGCGGGGCGTCTTTCAGAGGCTAAGGTGCCAACAGTATGACTATTGATGACTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGCTGATGCCGACTACGAGCCGAACTTCAAATTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGTAGTAGTTTCAGCATCATGGCTACTCGAACTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAAGAATCCAAAGCAAGAAAGGTTAATAGCTAATCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTGACACTATCGCTCCTATCGTTAACGTTCGTCTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCCACAGCATCAGCATATGCTGCAAATGTAAAGTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGTAGAGTTCTTCCCAAAAGCAAACAAACCACCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCTATTTCCACAAACGTATAGGTAACTGTGCTTATGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGTAGGAGTAGTAGTCTCAGCCTCATGGCTACTTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGTTCTATGCAACTAAACACCCCGTAGTAGGAATGGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGAAGTATCTTTAGCAATCGCTCAACGTAAATCAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTCGAAGCTGAGTTCGGATACCTGTTGTTGTCGTAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAGAGGCTCATACAAGCGTTATTAGCATATGTGTGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAAGTCATTGGTAACGGCGTCTACCCTTCAAGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGATAAATGCTATTGTGGTGTTTACTGATTCTCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAGCTCCACAGGTAATCCCCGTAGCTCAGGGATTGGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGACTTACCATCGATTACTTGATCCACCGCGGTATGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTGCGCAGGTGCTGTTTTGATGATTTATTCGCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAAAAAAGTTGTCATCGTTAAATCTCCGTAATGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCGCAAGCACTCCGTAGCCAACGGGATTGGTTGGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGTAACGCCATGGTGTGCTGCGTGTGGTCGGCCCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGCTAAGGCAGTATCGCGTTCATCTATATGGATTTCTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGAAGTCGGACACGTTTCATCTTACTTTGCTAAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCATGATGCGCACTGTCTACATCAAGGCAGCCTAAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGGTTAAAGGGGGCCGACTAAGACCTTTGGCATCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTTAAACCCGAACGGTTAGGGCTGATTTCACCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGATGAAACCCAGACCCCTGAGAAATATGTCCAACTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTCTCATTAAGAAACGTCTTGAAGATTTATCTACGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCAAGCGGTATGTATCGCCCTAGGTCGCCCACAAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAAAGGTATCACTCGCTTTATAGACCAAGGTGCGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAAATACCCTGAATACCAAGAAAAAGAAAGATAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTCAATAACGGCAAAACAGGCGGGACGGTAACTATGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

>LR134303|3|3|4614027-4616302|CRISPRCasFinder
GTCTAAGTCCCTTTAAATGGCGGGGCGTCTTTCAGAG	GCTAAGGTGCCAACAGTATGACTATTGATGACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCTGATGCCGACTACGAGCCGAACTTCAAATT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGTAGTTTCAGCATCATGGCTACTCGAACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAGAATCCAAAGCAAGAAAGGTTAATAGCTAATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TGACACTATCGCTCCTATCGTTAACGTTCGTCT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CCACAGCATCAGCATATGCTGCAAATGTAAAGT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGAGTTCTTCCCAAAAGCAAACAAACCACC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CTATTTCCACAAACGTATAGGTAACTGTGCTTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGGAGTAGTAGTCTCAGCCTCATGGCTACTT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTTCTATGCAACTAAACACCCCGTAGTAGGAATGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTATCTTTAGCAATCGCTCAACGTAAATCA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCGAAGCTGAGTTCGGATACCTGTTGTTGTCGTA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGAGGCTCATACAAGCGTTATTAGCATATGTGTG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAGTCATTGGTAACGGCGTCTACCCTTCAAG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATAAATGCTATTGTGGTGTTTACTGATTCTC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGCTCCACAGGTAATCCCCGTAGCTCAGGGATTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ACTTACCATCGATTACTTGATCCACCGCGGTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TGCGCAGGTGCTGTTTTGATGATTTATTCGC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAAAAGTTGTCATCGTTAAATCTCCGTAAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CGCAAGCACTCCGTAGCCAACGGGATTGGTTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAACGCCATGGTGTGCTGCGTGTGGTCGGCCC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCTAAGGCAGTATCGCGTTCATCTATATGGATTTCT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTCGGACACGTTTCATCTTACTTTGCTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CATGATGCGCACTGTCTACATCAAGGCAGCCTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GGTTAAAGGGGGCCGACTAAGACCTTTGGCATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TTAAACCCGAACGGTTAGGGCTGATTTCACC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATGAAACCCAGACCCCTGAGAAATATGTCCAACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCTCATTAAGAAACGTCTTGAAGATTTATCTAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CAAGCGGTATGTATCGCCCTAGGTCGCCCACAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAGGTATCACTCGCTTTATAGACCAAGGTGCG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAATACCCTGAATACCAAGAAAAAGAAAGATA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCAATAACGGCAAAACAGGCGGGACGGTAACTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

>LR134303|3|1|4614027-4616302|CRT
GTCTAAGTCCCTTTAAATGGCGGGGCGTCTTTCAGAG	GCTAAGGTGCCAACAGTATGACTATTGATGACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCTGATGCCGACTACGAGCCGAACTTCAAATT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGTAGTTTCAGCATCATGGCTACTCGAACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAGAATCCAAAGCAAGAAAGGTTAATAGCTAATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TGACACTATCGCTCCTATCGTTAACGTTCGTCT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CCACAGCATCAGCATATGCTGCAAATGTAAAGT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGAGTTCTTCCCAAAAGCAAACAAACCACC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CTATTTCCACAAACGTATAGGTAACTGTGCTTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGGAGTAGTAGTCTCAGCCTCATGGCTACTT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTTCTATGCAACTAAACACCCCGTAGTAGGAATGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTATCTTTAGCAATCGCTCAACGTAAATCA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCGAAGCTGAGTTCGGATACCTGTTGTTGTCGTA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGAGGCTCATACAAGCGTTATTAGCATATGTGTG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAGTCATTGGTAACGGCGTCTACCCTTCAAG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATAAATGCTATTGTGGTGTTTACTGATTCTC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGCTCCACAGGTAATCCCCGTAGCTCAGGGATTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ACTTACCATCGATTACTTGATCCACCGCGGTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TGCGCAGGTGCTGTTTTGATGATTTATTCGC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAAAAGTTGTCATCGTTAAATCTCCGTAAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CGCAAGCACTCCGTAGCCAACGGGATTGGTTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAACGCCATGGTGTGCTGCGTGTGGTCGGCCC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCTAAGGCAGTATCGCGTTCATCTATATGGATTTCT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTCGGACACGTTTCATCTTACTTTGCTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CATGATGCGCACTGTCTACATCAAGGCAGCCTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GGTTAAAGGGGGCCGACTAAGACCTTTGGCATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TTAAACCCGAACGGTTAGGGCTGATTTCACC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATGAAACCCAGACCCCTGAGAAATATGTCCAACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCTCATTAAGAAACGTCTTGAAGATTTATCTAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CAAGCGGTATGTATCGCCCTAGGTCGCCCACAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAGGTATCACTCGCTTTATAGACCAAGGTGCG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAATACCCTGAATACCAAGAAAAAGAAAGATA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCAATAACGGCAAAACAGGCGGGACGGTAACTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

>LR134303|3|1|4614306-4616302|PILER-CR
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TGACACTATCGCTCCTATCGTTAACGTTCGTCT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CCACAGCATCAGCATATGCTGCAAATGTAAAGT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGAGTTCTTCCCAAAAGCAAACAAACCACC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CTATTTCCACAAACGTATAGGTAACTGTGCTTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGGAGTAGTAGTCTCAGCCTCATGGCTACTT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTTCTATGCAACTAAACACCCCGTAGTAGGAATGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTATCTTTAGCAATCGCTCAACGTAAATCA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCGAAGCTGAGTTCGGATACCTGTTGTTGTCGTA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGAGGCTCATACAAGCGTTATTAGCATATGTGTG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAGTCATTGGTAACGGCGTCTACCCTTCAAG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATAAATGCTATTGTGGTGTTTACTGATTCTC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGCTCCACAGGTAATCCCCGTAGCTCAGGGATTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ACTTACCATCGATTACTTGATCCACCGCGGTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TGCGCAGGTGCTGTTTTGATGATTTATTCGC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAAAAGTTGTCATCGTTAAATCTCCGTAAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CGCAAGCACTCCGTAGCCAACGGGATTGGTTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAACGCCATGGTGTGCTGCGTGTGGTCGGCCC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCTAAGGCAGTATCGCGTTCATCTATATGGATTTCT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTCGGACACGTTTCATCTTACTTTGCTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CATGATGCGCACTGTCTACATCAAGGCAGCCTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GGTTAAAGGGGGCCGACTAAGACCTTTGGCATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TTAAACCCGAACGGTTAGGGCTGATTTCACC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATGAAACCCAGACCCCTGAGAAATATGTCCAACT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCTCATTAAGAAACGTCTTGAAGATTTATCTAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CAAGCGGTATGTATCGCCCTAGGTCGCCCACAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAGGTATCACTCGCTTTATAGACCAAGGTGCG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAATACCCTGAATACCAAGAAAAAGAAAGATA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCAATAACGGCAAAACAGGCGGGACGGTAACTAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

Protein	Signature genes	Signature genes Name	Protein_function
LR134303.1\|VEE64250.1\|4619031_4619619_-\|Helix-destabilizing-protein	unknown	unknown	gnl\|CDD\|136097
LR134303.1\|VEE64235.1\|4599258_4600347_-\|Uncharacterized-oxidoreductase-yvaA	unknown	unknown	gnl\|CDD\|223745
LR134303.1\|VEE64241.1\|4607844_4610949_+\|Site-specific-recombinase-XerD	unknown	unknown	gnl\|CDD\|271189
LR134303.1\|VEE64238.1\|4602594_4603752_+\|Alcohol-dehydrogenase-YqhD	unknown	unknown	gnl\|CDD\|224890
LR134303.1\|VEE64246.1\|4616439_4616757_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
LR134303.1\|VEE64248.1\|4617706_4617985_-\|CRISPR-associated-protein-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
LR134303.1\|VEE64253.1\|4622462_4622765_-\|putative-CRISPR-associated-protein,-VVA1548-family	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|370601
LR134303.1\|VEE64239.1\|4604762_4605341_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64244.1\|4613172_4613850_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|373093
LR134303.1\|VEE64249.1\|4618008_4619031_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|226990
LR134303.1\|VEE64251.1\|4619619_4621851_-\|Probable-ATP-dependent-helicase-dinG-homolog	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
LR134303.1\|VEE64243.1\|4611866_4613153_-\|CRISPR-associated-protein,-NE0113-family	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|187817
LR134303.1\|VEE64236.1\|4600414_4600858_-\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|227262
LR134303.1\|VEE64252.1\|4621864_4622155_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64255.1\|4623549_4624431_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|226124
LR134303.1\|VEE64237.1\|4600874_4602053_-\|multidrug-efflux-system-protein-MdtL	unknown	unknown	gnl\|CDD\|340883
LR134303.1\|VEE64242.1\|4611135_4611831_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64240.1\|4605337_4607875_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64254.1\|4622761_4623550_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|206648
LR134303.1\|VEE64247.1\|4616743_4617703_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633

Protein	Function_ID	Function_description	E-value
LR134303.1\|VEE64250.1\|4619031_4619619_-\|Helix-destabilizing-protein	gnl\|CDD\|136097	PRK06863, PRK06863, single-stranded DNA-binding protein; Provisional.	3.93849e-48
LR134303.1\|VEE64235.1\|4599258_4600347_-\|Uncharacterized-oxidoreductase-yvaA	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.73159e-43
LR134303.1\|VEE64241.1\|4607844_4610949_+\|Site-specific-recombinase-XerD	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.26029e-09
LR134303.1\|VEE64238.1\|4602594_4603752_+\|Alcohol-dehydrogenase-YqhD	gnl\|CDD\|224890	COG1979, COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion].	0
LR134303.1\|VEE64246.1\|4616439_4616757_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	1.03039e-11
LR134303.1\|VEE64248.1\|4617706_4617985_-\|CRISPR-associated-protein-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.81213e-07
LR134303.1\|VEE64253.1\|4622462_4622765_-\|putative-CRISPR-associated-protein,-VVA1548-family	gnl\|CDD\|370601	pfam09652, Cas_VVA1548, Putative CRISPR-associated protein (Cas_VVA1548). This entry represents a conserved region of about 95 amino acids found exclusively in species with CRISPRs (Clustered Regularly Interspaced Short Palindromic Repeats). In all bacterial species that contain this entry, the genes encoding the proteins are in the midst of a cluster of cas (CRISPR-associated) genes.	3.88762e-32
LR134303.1\|VEE64244.1\|4613172_4613850_-\|Uncharacterised-protein	gnl\|CDD\|373093	pfam14487, DUF4433, Domain of unknown function (DUF4433). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 201 and 230 amino acids in length. There is a single completely conserved residue E that may be functionally important. This family is distantly similar to pfam01885 suggesting these may be ADP-ribosylases.	9.91754e-20
LR134303.1\|VEE64249.1\|4618008_4619031_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|226990	COG4643, COG4643, Uncharacterized protein conserved in bacteria [Function unknown].	1.84258e-10
LR134303.1\|VEE64251.1\|4619619_4621851_-\|Probable-ATP-dependent-helicase-dinG-homolog	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	2.68939e-148
LR134303.1\|VEE64243.1\|4611866_4613153_-\|CRISPR-associated-protein,-NE0113-family	gnl\|CDD\|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	9.16309e-80
LR134303.1\|VEE64236.1\|4600414_4600858_-\|Uncharacterized-conserved-protein	gnl\|CDD\|227262	COG4925, COG4925, Uncharacterized conserved protein [Function unknown].	6.53432e-41
LR134303.1\|VEE64255.1\|4623549_4624431_-\|GTPase-Era	gnl\|CDD\|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	8.08317e-55
LR134303.1\|VEE64237.1\|4600874_4602053_-\|multidrug-efflux-system-protein-MdtL	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.62257e-19
LR134303.1\|VEE64254.1\|4622761_4623550_-\|GTPase-Era	gnl\|CDD\|206648	cd00882, Ras_like_GTPase, Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases). Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.	1.63238e-18
LR134303.1\|VEE64247.1\|4616743_4617703_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.6891e-66

>LR134303.1|VEE64244.1|4613172_4613850_-|Uncharacterised-protein
MLVLNQYAFAPKTGSDLTSSLRSRGIQRLLHFTLVDNLASIIKYGLLGRTELEQRQLNYIYTDNKRLDGNPNAICLSITSPNYKMFFSKRNSFSQLGYQDSDWVVILLKPEVLLNLPAAFTFTNAADSRCRGQWQRHSSREAFEAMFYDEALRATLGLNPKQPTNPQAEIQVMRSIPSDWIDAIVCHPNADIRKLQSVAGNLPVLPIYEAFAPRHDYSYWSVNYN
>LR134303.1|VEE64243.1|4611866_4613153_-|CRISPR-associated-protein,-NE0113-family
MQKHILLAITGLSPQVVTETLYAIHQQQLEWPTEIRLITTLTGKNQARLGLLIPPEGKSLNRLQQLCADYNRPVPTFTEAHIAIVPNAEGQEVDDARSNADQESLADFIVSQVAQLANDDECQIHASLAGGRKTMTFYLGYAMSLFARPQDRLSHVLVDAQFEGLRDFYYPTPATCVINGRDPNTNLDAADAKVTLAEIPFISQRQSLAKTTLAAFAHSPAVQPPSYRDLVRYENLAQDRDNLSLTFNTKDRLVVLGSTQGEDINIDFNDAPLQLAFFAMMARHSQLANPIKLVRSKDANKTYAHLFLQELERIEGLPVTHMATEADYGYRIEQFRNQFLRSTQDRTLDSLKQGMDAQFWDDRKNQLKQYLSKQFPESMLDCLLPGPVFKPKKQNRNQFEPTAFDGRNPQGAAWGLWLKQTNIHFNDQ
>LR134303.1|VEE64242.1|4611135_4611831_-|Uncharacterised-protein
MANRPLFTPHSASISTKTHSVEFNWHPGLAASQKHKSVAELHQSAKQQGLCRRPLEVSSKSLEPLGIALSAFNLQVPLGNGKHTYVENVFQAAKVFEHAGPFIDLLYVSPLEAKRDPRLKENGMLQYFHGNAGHRWPLQPTTLFYDWVYLNALVRNPQLCEQVMDYDGFTDIEFNPNKSLNCQAQSVALFISLTQAGLLRQALASPLAFTELTTKVWREISSAIPEQQSLL
>LR134303.1|VEE64241.1|4607844_4610949_+|Site-specific-recombinase-XerD
MATTKIRYFINQLYSQGKLHPLYREVFDAFVKQNGHTIDKEKQNKVKDAFFLSYKQLLGHVKTRFILSETKVLPEELTDLIAQLKPAVLNKQVQLLILQSILNYAKKHHGIDSPNIPAIVTLKRDKPILTPVELVKLPIVERIYALLDKELITPHRTLTSEQKIGRAALLVYLTVNVSKTEELLSILETPNNVFYVGGICYWQSQQTNAASTRFVLSDVAVMALQQLSSLKQGSIKIAACIIKYLNITSEFDWSDLSILKLRTLRKIDNVIHYGPVQYQMYCLPSVSQALPEHAFMRVLTDKACLYSAPHLLGTMREGANELKPWRKVIKQHHSFIAIDVTLRQLDDIFLRLSGLDESNAPRANCIAFISEVLKSSEVTANPYLWMLCSWLLSLLKNGGTYKHRLKVSTTVDYVKSFSKPFLTEFCTSDIGLLSGEDWANKLNEAAELFTSAQRKKYVYYFAQFLIETNLVRDLCLSDIDVVGSSSEVDANLISATHIDEVLKYLTKHVEEGLIYQYAYFLLCFCFFTGLRRNETAKLTWADLSFALSAPDDEQFDYVQLSVRPNKHRTLKTTSARRELPLDALWPKSALQKLRIQHQIHQNSKANKKALLFDNPKLVNQAYDLITDLIRHYTQDYGLRVHHLRHSFANWTWCRLNPKIINQGKTQLTMFDHEQFNHDYLERLQTRLRHHMNTRKKMFMLAHLLGHKDVQSTLNSYLHLKDILYYLELTPRFALTKYFTSECVGRVSLLEPEQGLSLAERVIYYTRDIEAKLAIKPASLASSLFRPTLSTFVLDIKPNIEISSLTWAKALNALKVCSVIESSQHFNVPMEQLQQLLHNAEQVHQLYPRVGKPLPLIPAFPKLNHSHNEAEPDEHLAKSSKVFIYLCNKFDKNVGIEPLTLANVRLSMEILNYAVPGKDYALRCPNSKVSRMFIRFCQLLGLKDRHLKFRFHRADLTIEESQRVENRWKKTVLGCGFNDGNFVVASESEGRFLGKHDGNGFLEIALVNNGYKRVQRHQSLFSFLHFLLILSYQEE
>LR134303.1|VEE64240.1|4605337_4607875_+|Uncharacterised-protein
MTKLKQHLHEHICRYCDHMMLGIGKDEVLEDLEELIERVFAPESLGGFKQLIDLVVRVRMHSFHSAQSIMKDLHLAPYIFDALHNYSFEADDKSINSEYHRNSYKNGWCSEYPFYVLLLKSHEYHFTIKSCELLAAFIKHYYSVLDTLRDHDLARASSTREEDACANFRLFMKTNVAEFNFVRESIPKTALDSPISIANQIDQYLISKETWPYLVHKNYLRMLCHFFYNDWEQPKHFTRRGSPSDRVPKRYKDPIAIPIVGAYDDTFALIPGKPSLPNSDGLDDDDQYAAQTFVVNNRDVNTQRDKTELLDTAIPFNKHVQSRTAIDVTASVRRSHNMGLQNTQLLMPEELNLLINKLIKLANQPVNLETAIVMWLMMLLSKSIEDIHNLVVFTDLRAKQQGLYIDEFGQGWWLFYVSHSAKSKLDNVGLRPVKEDVFTACPDFLLKLIVKNMGARANGPIINEENTQVIIDNVAKKLKKISDRHSSGRLSVRRLVNFTSYYLNSTDVIDPIYIDYSYAVNMYTTRVARSYANLRDHARSQQLDKLWKSVEQDIELYSGKPLSISLFDLRHLSQCEQFIGSSFTPTKTVVSTLINSLTQRVLSSKPSFQHRLVDIIEYHNAFTAYTAWMLLFGTGYRAAWNPLPTFALFLPSLNLMGISDKDDSDFSHSRIVAVPTALATQLKEYKRHLGCLRSLLRVLMPKLCSRIDRIVDVDQHVLSFNYSQASQWYKVIRNSRKEQGPFFFFHQQGTSVVTQNLSPSALVNYCRDAILLPSNAGRHWLKSHLLEKNITPELINFQMGHWQAGEVPLGHYSALSHVEAINDIVPVLDELFEEVGWLPLKSVIL
>LR134303.1|VEE64239.1|4604762_4605341_+|Uncharacterised-protein
MNIHAEHFKASLDRLLVDVKLEKVAFHQIQLDRELKIFCESFNLLSTLKPSSDDGFESSASILLDSYQVPLLVSKTEAGYYRLISGLLTFQKLCKIYTVNDKSLVPCLVLPRRPNKEILRLLILNDLVRPLLKQFVDVTGDTITQTLSTLFTSVANPSVFNSPQWQSLFPMIKTKTQLCEWLHISTKTVKLK
>LR134303.1|VEE64238.1|4602594_4603752_+|Alcohol-dehydrogenase-YqhD
MNNFSFFNNTKIIFGEGQINQLTQEIPADATVMIIYGGGSIKKNGIFDQVVNALEGKKWVEFGGIEPNPHYDTCLKAVEKIKQEDVDFLLAVGGGSVIDATKFIAAAAKHQGDPWAIIQSFGGAVQGALPIGCVLTLAATGSEMNPTAVVTRADTQDKLFFNSDYVRPHFSILDPQTTYSLPARQVGNGVVDSFVHVLEQYVTYPVNAKVQDRFAEGLLATILEEGPRALIEPENYDVRANLMWAATMALNGLIASGVPADWATHLIGQEITGLYGLDHAQTLAIVMPAVWTYKVEQKREKLAQYGRRVLGIIEADDLVAAEKAIVRSREFFEAMGVRTRLADYGLSADIIPNIIAKLQEHQFIQLGEHGDITPDDVSKILKLAL
>LR134303.1|VEE64237.1|4600874_4602053_-|multidrug-efflux-system-protein-MdtL
MDSTGNKTTFWAASSALAATFIASATPIPLYGTYQRVDGISYLGLSLSSVIYFVGAVTALLIFGRLSNHFGRKPISLIAVLLAALASSLFLDVHTVTPLLIGRLFQGLSCGLASTALAAWIVDCATTVPKWVAPAVISCGPMTGLTIGGIVSGLLVEYSALPRQLPFYLVLALLLICIFTLIKSKETVRHTSGAINSLLPRFALPETAKRAYPIAAITFVCTWSLGGFFQAFGPAMAAEQLHSTNAVAAALVFASIMAPSVVGASLASKMTPKSAQYYGMLSFTVFVFAVWLSLYVGILTAFLISSVLAGIAQGLVLTGSIQTMVGQLKAEQRANVLSVIYATSYTGAAIPTLIAGRLSENVGLLGTASGYVGLAFIGAVAVIRHTRSPIKA
>LR134303.1|VEE64236.1|4600414_4600858_-|Uncharacterized-conserved-protein
MGNARGWLMLLSLFSTVSSAEITSKSQENLVKIYIDIQGNTISGTLKSDSDAAKSFAALLPLQLKLSDYAATEKVADLPKPLSTQNEPAGTAAKVGDITYYAPWGNLAIFHKSFGYANGLVALGTLDSGIELMRKPGELDVTIRLAD
>LR134303.1|VEE64235.1|4599258_4600347_-|Uncharacterized-oxidoreductase-yvaA
MAQPIRIGFIGLNPDSHWAATAHIPALSTLIDKFQVIGVANSSAESAQRTAKALNLPYAFSDVDELVNSPEIDLVVVTVKVPHHLKLVTAAINAGKHVYCEWPLANGVAEAKTLANLANSKGVVAVCGTQARMAPEIIHLTKLISEGYVGKVLSTSLIGSGGNWAGETINEYYYLFDAQNGANMQTIPLAHTLAAIKDVLGEFGSLSARFLSNFDTVTVTDTNEIKPKTVPDQLMIHGCLKSGAAIAVHYRGGVNRGTNFLWEINGTEGDIQVSAGLGHAQMVQLTIKGARGDETTLKTILPAPSLYQGKPEAAAARNVAGVYNALYHDIVNGTQTAPSFNDAVALHQLIDNIERSAKCCAE
>LR134303.1|VEE64246.1|4616439_4616757_-|CRISPR-associated-endoribonuclease-Cas2
MNSTEHWYLICYDIRKPQRLQKLQRYLRRCCLKLQDSVYLFCGNYRQGEQLRQAISQRISRSVDDVRVYQLPSQSQFKFYGQLPWTVDIFYPGLPSFSHTPATVA
>LR134303.1|VEE64247.1|4616743_4617703_-|CRISPR-associated-endonuclease-Cas1
MTTLILEKHGISLEYDTDVLVIREAEMPPRTIPLSRIDKVVCLHNTALSTQLLGQLHQRGIDFIVLNSRYTDHCVALYADTHGNCLRRAAQYTLQLDNKERLPLAKSLCHHKLQQSLRVLDAQQPGRLQSQLQMAQESVRNCQDEQQLRGLEGSAQRALFQHWRQQLDPKWGFERRERRPPPDPVNGLLSLTYTLVHHEAIRQCKQYGLDSTLGIYHRMAYGRHSLACDLMEPTRPIIEQWLVQLLDTDLLTQRHFTKGKPGCYLGKEGRLLFYPQLETQMALIRRKLAANARWMVQQLDHGLTQGQYTLSEASAYELN
>LR134303.1|VEE64248.1|4617706_4617985_-|CRISPR-associated-protein-Cas2
MMKQQNILIAYDIQSDNARSCALYNLRKFAISYQDSVFELQLSAAKLQRLILKLQPYISTNDTLLSVHFSPNACWQLGCGLPSISGQFLVIG
>LR134303.1|VEE64249.1|4618008_4619031_-|Uncharacterized-protein-conserved-in-bacteria
MSQDILWQARNEIIALSAEVGIDGSALLNALPSSSQLLTGSQVPTLSPRYRGKCSVLFHIHQMRNGKSWPWMRLHTFKHGGISRVFNGLQWQRQNSATHWPITPHFGQSNTVSTPQPPSASATLADWRATRFASLQVQYQALPTLTPTHPWLQQRFAAQLPSAVLQRCHLRGNHQQLLLPLQHHHGEISGFQLLTWGENAQKRFWLRRQGLLTGSYALISGQPGPVALCEGLATALSIALAWPGKIYIGLCANNLAAVRAKITGKVVIFYDNDNWKPDYGNPGQQAALACRQTRDILVGPQFSSEQQQTKPTDFNDLHNLAGIAELMHQIRRHWTVKSSY
>LR134303.1|VEE64250.1|4619031_4619619_-|Helix-destabilizing-protein
MTTGINKVILIGHLGKAPEIKTLNDGVRLCNLSLATSERWTNKQTGQAQEHTEWHRLVLSDRLAEIAEKYLQKGSKIYIEGKLRTRKWQNQLGQEQYTTEVRVAQLQILSSRAQEATKTAEDYSKAVSPVQPVSPVQQVSPTITKLQPIRRMLTILTWMIGTIFLFEVVRHGTISLGNSIVNHSIMWKSKPHLGG
>LR134303.1|VEE64251.1|4619619_4621851_-|Probable-ATP-dependent-helicase-dinG-homolog
MLNYQDNNPTQQHSIDIAEVKLANAKLWQAQSQQLYTTLSQAIAGFKSRAGQQQIVELCANNSAQHGQLVVEAGTGVGKTFGYILGHLPAILQNEQRLLISTNTITLQNQLMEKDLPQLLAILAPELTYTIAKSGSRYLCPAKVRSLLTKTEKNTDADSTDDMFDSASPVNMSSAQLQCLKEVYTLFTEGNFAGDLDQLQVANAPQYQKLLNRDQQRCPGQRGCSDGKQCPFYLQREKISKTDIVVTNHAFLVNVLMHDSNAFGDLTNTMLVLDEAHHLPKVIRDVNQAELDLSQAAEIADQFDKLEKASNKLIKTQPALFDDINKFTTSIQRLKPAITDFCEQLQQLNEHMSLNFMAYRGKKQNSFDDIEQWLMSYAPMPISFVTPLLNLYQSCATARTYVEQLNGQFRQQLDNKDIPQAAENACNRWLQSSANLLAMVAQAHHCLDYYYQFTNQQTEDQRLDVGIARWVKNDAATDKITLLANVIDVSQHFQLRIAQAFKSQVLTSATLKTLGSFNHINRQLGINSETSIHADIPSDFNYRHAFLSWAPSNAPEPNNEHFIGYLTQQIMELTQRHSAILVIFTAHNMLESTFNLMPTALKQQILCQDKRSKSELIQEHKRRIDAGQTSILFGVDSLSEGLDLQGKYLTGVVIAKLPFPSLSEPLINYEKITLDARGINSFAQMMVPECSRKLIQSVGRLIRSEQDWGEVFIADRRIQPRPFSNYYGNILLNALPIFQQGVR
>LR134303.1|VEE64252.1|4621864_4622155_-|Uncharacterised-protein
MMSSSSPYIFGQQANSQWQKRPLGRVGDLQGWHQRMKALCPNPRLGQVVWLENNHWDNGEGQYVHSSTGYKVINFRANGDPVWERGQVIILSTDDE
>LR134303.1|VEE64253.1|4622462_4622765_-|putative-CRISPR-associated-protein,-VVA1548-family
MNKRIWLVSRHPGAQTWLKQQGFQGQQIAHLDIDTIAAGDIIIGSLPIHMVVALTLKNAEYWHLSMTIPECWRGTELTPEQMQLCQIKLQKITAQAEDFF
>LR134303.1|VEE64254.1|4622761_4623550_-|GTPase-Era
MKPTLRCTVKIERDVVALVQARNAFGFLHNRQPLLSLASRWQRGDSLSHDIQVIAIGKSGYGKSTTLNQLVGEAVFETNAIAGCTREMQSAEYRFPTKEAQCHFSLADLPGIGEHPELDKQYIQLYRDAIAKAHSVIYFLRADQRDYVIDQWAFAQLFNTDAERRKVIIALNAVDKIEPLNRSQPFALTAEQIQSLRLKRHTICQQFAVCEDQIVTLSATEQHNLDGLVDRLADVLQPYLSQADTTSAYQAHWTSSVNGATY
>LR134303.1|VEE64255.1|4623549_4624431_-|GTPase-Era
MMNNIIAILQDLDSQLAPAQVERIREKLTSMLNYRPRIGVFGKTGVGKSSLCNALFGKPICAISDIEACTRDPQEVMLNMENGKGITLLDVPGVGENLQRDEEYSELYRKLLPELDMVLWVLKADDRAYSVDIEFYTNVVKPHLQQGKPFILVLNQVDKIEPFRDWDGENRKPGPSQAQNIALKAANVATHFQVKQSLVVPVSADEKFGLTKLVDEIIFSLPDEKKVSIAREVPAENLSTESKAEVKNSLSRVLTRTLTGVATGAALGSKIAGKAGAVVGGVIGGIGGFLGLW

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Crispr_ID: LR134303_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134303_4

4625297-4626449

TypeIII

Consensus_repeat	Method
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CRISPRCasFinder
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CRT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	PILER-CR

16 spacers

csx16,DinG,cas2,cas1,csx1,cas6,csm3gr7,csx10gr5,cas10

The CRISPR arrays of LR134303_4

>merge|LR134303|4|4625297-4626449|CRISPRCasFinder,CRT,PILER-CR
ACATTAACCCCCTAAAATCGCGGGGAGTCTTTCAGAGCCGTCAGAACTTCTCACCGAGTGATGTCGGTAAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAAAATACACCTATCTCCCGGGGATGTTCTCACGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGACCATTGCGTCTTACAAGAAGACCGAACAATGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCCAACACCCATGAATCATGCGGGTAAGTATCTAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTCAAAAAATCCAACTGACATCGAAAAACAAGTGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCAACTACACACATATTGCCAATATCAGCGCTACGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGAGTACGACGCGATAGTGGCCGACGACTTCGATGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGCATTATCAGCTACAGTGCAGGTCGGATACACGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGATTTCATTGGCTTCTTCAATAACCTTTTTAGTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCTATAAGACAATCCGTCTTATCTGTGAGGAACGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGTTACAGCTTAACCTTACCGCGTACTCAGAGCTTCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGAAAAGCATAATGCATTCAGTTTCACTAAGTTTGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGAAGTATGAACAAGAGAAGTCTACTTGGAATATCGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGCGAGTGATGCTAGGCGTGATGGTAGGTAGCTGGGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGAGCCAAGCAGCAGCTCACGAAGTAAATCAAGCAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAGGTAGTACGTGTATTCAGTACTATTGATAAAACAGTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

>LR134303|4|4|4625297-4626449|CRISPRCasFinder
ACATTAACCCCCTAAAATCGCGGGGAGTCTTTCAGAG	CCGTCAGAACTTCTCACCGAGTGATGTCGGTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAATACACCTATCTCCCGGGGATGTTCTCAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ACCATTGCGTCTTACAAGAAGACCGAACAAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CCAACACCCATGAATCATGCGGGTAAGTATCTA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCAAAAAATCCAACTGACATCGAAAAACAAGTG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CAACTACACACATATTGCCAATATCAGCGCTAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAGTACGACGCGATAGTGGCCGACGACTTCGAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCATTATCAGCTACAGTGCAGGTCGGATACAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATTTCATTGGCTTCTTCAATAACCTTTTTAGT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CTATAAGACAATCCGTCTTATCTGTGAGGAAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TTACAGCTTAACCTTACCGCGTACTCAGAGCTTC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAAAGCATAATGCATTCAGTTTCACTAAGTTT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTATGAACAAGAGAAGTCTACTTGGAATATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CGAGTGATGCTAGGCGTGATGGTAGGTAGCTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGCCAAGCAGCAGCTCACGAAGTAAATCAAGCA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGTACGTGTATTCAGTACTATTGATAAAACA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

>LR134303|4|2|4625297-4626449|CRT
ACATTAACCCCCTAAAATCGCGGGGAGTCTTTCAGAG	CCGTCAGAACTTCTCACCGAGTGATGTCGGTAA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAATACACCTATCTCCCGGGGATGTTCTCAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ACCATTGCGTCTTACAAGAAGACCGAACAAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CCAACACCCATGAATCATGCGGGTAAGTATCTA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCAAAAAATCCAACTGACATCGAAAAACAAGTG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CAACTACACACATATTGCCAATATCAGCGCTAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAGTACGACGCGATAGTGGCCGACGACTTCGAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCATTATCAGCTACAGTGCAGGTCGGATACAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATTTCATTGGCTTCTTCAATAACCTTTTTAGT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CTATAAGACAATCCGTCTTATCTGTGAGGAAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TTACAGCTTAACCTTACCGCGTACTCAGAGCTTC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAAAGCATAATGCATTCAGTTTCACTAAGTTT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTATGAACAAGAGAAGTCTACTTGGAATATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CGAGTGATGCTAGGCGTGATGGTAGGTAGCTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGCCAAGCAGCAGCTCACGAAGTAAATCAAGCA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGTACGTGTATTCAGTACTATTGATAAAACA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

>LR134303|4|2|4625367-4626449|PILER-CR
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AAAATACACCTATCTCCCGGGGATGTTCTCAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ACCATTGCGTCTTACAAGAAGACCGAACAAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CCAACACCCATGAATCATGCGGGTAAGTATCTA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TCAAAAAATCCAACTGACATCGAAAAACAAGTG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CAACTACACACATATTGCCAATATCAGCGCTAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAGTACGACGCGATAGTGGCCGACGACTTCGAT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GCATTATCAGCTACAGTGCAGGTCGGATACAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	ATTTCATTGGCTTCTTCAATAACCTTTTTAGT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CTATAAGACAATCCGTCTTATCTGTGAGGAAC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	TTACAGCTTAACCTTACCGCGTACTCAGAGCTTC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAAAGCATAATGCATTCAGTTTCACTAAGTTT
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GAAGTATGAACAAGAGAAGTCTACTTGGAATATC
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	CGAGTGATGCTAGGCGTGATGGTAGGTAGCTGG
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	AGCCAAGCAGCAGCTCACGAAGTAAATCAAGCA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG	GTAGTACGTGTATTCAGTACTATTGATAAAACA
GTCTTAATCCCCTTAAATGGCGGGGCGTCTTTCAGAG

Protein	Signature genes	Signature genes Name	Protein_function
LR134303.1\|VEE64266.1\|4636953_4637553_-\|CRISPR-associated-RAMP-protein,-SSO1426-family	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
LR134303.1\|VEE64258.1\|4626828_4627335_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64264.1\|4634009_4635419_-\|CRISPR-associated-RAMP-protein,-SSO1426-family	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
LR134303.1\|VEE64249.1\|4618008_4619031_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|226990
LR134303.1\|VEE64256.1\|4624494_4624833_-\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|225876
LR134303.1\|VEE64250.1\|4619031_4619619_-\|Helix-destabilizing-protein	unknown	unknown	gnl\|CDD\|136097
LR134303.1\|VEE64248.1\|4617706_4617985_-\|CRISPR-associated-protein-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
LR134303.1\|VEE64261.1\|4630313_4631192_-\|Uncharacterized-conserved-protein-(DUF2276)	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|337605
LR134303.1\|VEE64263.1\|4633484_4634006_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64259.1\|4627641_4628913_-\|CRISPR-associated-protein,-NE0113-family	csx1	pfam09623_csx1_CAS-III	gnl\|CDD\|187872
LR134303.1\|VEE64262.1\|4631188_4633483_-\|CRISPR-associated-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
LR134303.1\|VEE64253.1\|4622462_4622765_-\|putative-CRISPR-associated-protein,-VVA1548-family	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|370601
LR134303.1\|VEE64265.1\|4635421_4636954_-\|CRISPR-associated-RAMP-protein,-Csx10-family	csx10gr5	cls000748_csx10gr5_CAS-III-D	gnl\|CDD\|131722
LR134303.1\|VEE64267.1\|4637549_4639274_-\|Uncharacterised-protein	cas10	cls000686_cas10_CAS-III	unknown
LR134303.1\|VEE64251.1\|4619619_4621851_-\|Probable-ATP-dependent-helicase-dinG-homolog	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
LR134303.1\|VEE64260.1\|4629041_4630235_-\|Domain-of-uncharacterised-function-(DUF1887)	csx1	pfam09002_csx1_CAS-III	gnl\|CDD\|312526
LR134303.1\|VEE64255.1\|4623549_4624431_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|226124
LR134303.1\|VEE64252.1\|4621864_4622155_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134303.1\|VEE64254.1\|4622761_4623550_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|206648
LR134303.1\|VEE64247.1\|4616743_4617703_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
LR134303.1\|VEE64261.1\|4630313_4631192_-\|Uncharacterized-conserved-protein-(DUF2276)	cas6	mkCas0066_cas6_CAS-I:CAS-III	1.1e-59	196.9	0.5
LR134303.1\|VEE64267.1\|4637549_4639274_-\|Uncharacterised-protein	cas10	cls000686_cas10_CAS-III	5.3e-147	485.2	0.0
LR134303.1\|VEE64264.1\|4634009_4635419_-\|CRISPR-associated-RAMP-protein,-SSO1426-family	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	4.8e-24	80.4	0.1
LR134303.1\|VEE64248.1\|4617706_4617985_-\|CRISPR-associated-protein-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	8.8e-12	39.8	0.0
LR134303.1\|VEE64266.1\|4636953_4637553_-\|CRISPR-associated-RAMP-protein,-SSO1426-family	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	1.6e-17	58.3	0.0
LR134303.1\|VEE64260.1\|4629041_4630235_-\|Domain-of-uncharacterised-function-(DUF1887)	csx1	pfam09002_csx1_CAS-III	2.1e-55	182.6	0.0
LR134303.1\|VEE64262.1\|4631188_4633483_-\|CRISPR-associated-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.8e-100	331.8	0.0
LR134303.1\|VEE64253.1\|4622462_4622765_-\|putative-CRISPR-associated-protein,-VVA1548-family	csx16	pfam09652_csx16_CAS-I:CAS-III	9.9e-30	97.4	0.1
LR134303.1\|VEE64265.1\|4635421_4636954_-\|CRISPR-associated-RAMP-protein,-Csx10-family	csx10gr5	cls000748_csx10gr5_CAS-III-D	5.9e-33	108.6	0.0
LR134303.1\|VEE64251.1\|4619619_4621851_-\|Probable-ATP-dependent-helicase-dinG-homolog	DinG	COG1199_DinG_CAS-IV-A	5.6e-100	330.2	0.1
LR134303.1\|VEE64259.1\|4627641_4628913_-\|CRISPR-associated-protein,-NE0113-family	csx1	pfam09623_csx1_CAS-III	7.3e-73	239.7	0.3
LR134303.1\|VEE64247.1\|4616743_4617703_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	2.6e-68	225.1	0.0

Protein	Function_ID	Function_description	E-value
LR134303.1\|VEE64266.1\|4636953_4637553_-\|CRISPR-associated-RAMP-protein,-SSO1426-family	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.77022e-16
LR134303.1\|VEE64264.1\|4634009_4635419_-\|CRISPR-associated-RAMP-protein,-SSO1426-family	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	2.61149e-18
LR134303.1\|VEE64249.1\|4618008_4619031_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|226990	COG4643, COG4643, Uncharacterized protein conserved in bacteria [Function unknown].	1.84258e-10
LR134303.1\|VEE64256.1\|4624494_4624833_-\|Uncharacterized-conserved-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	3.00456e-22
LR134303.1\|VEE64250.1\|4619031_4619619_-\|Helix-destabilizing-protein	gnl\|CDD\|136097	PRK06863, PRK06863, single-stranded DNA-binding protein; Provisional.	3.93849e-48
LR134303.1\|VEE64248.1\|4617706_4617985_-\|CRISPR-associated-protein-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.81213e-07
LR134303.1\|VEE64261.1\|4630313_4631192_-\|Uncharacterized-conserved-protein-(DUF2276)	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	9.92418e-06
LR134303.1\|VEE64260.1\|4629041_4630235_-\|Domain-of-uncharacterised-function-(DUF1887)	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	3.15309e-45
LR134303.1\|VEE64262.1\|4631188_4633483_-\|CRISPR-associated-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.97575e-88
LR134303.1\|VEE64253.1\|4622462_4622765_-\|putative-CRISPR-associated-protein,-VVA1548-family	gnl\|CDD\|370601	pfam09652, Cas_VVA1548, Putative CRISPR-associated protein (Cas_VVA1548). This entry represents a conserved region of about 95 amino acids found exclusively in species with CRISPRs (Clustered Regularly Interspaced Short Palindromic Repeats). In all bacterial species that contain this entry, the genes encoding the proteins are in the midst of a cluster of cas (CRISPR-associated) genes.	3.88762e-32
LR134303.1\|VEE64265.1\|4635421_4636954_-\|CRISPR-associated-RAMP-protein,-Csx10-family	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	1.28677e-09
LR134303.1\|VEE64251.1\|4619619_4621851_-\|Probable-ATP-dependent-helicase-dinG-homolog	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	2.68939e-148
LR134303.1\|VEE64259.1\|4627641_4628913_-\|CRISPR-associated-protein,-NE0113-family	gnl\|CDD\|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	8.75427e-72
LR134303.1\|VEE64255.1\|4623549_4624431_-\|GTPase-Era	gnl\|CDD\|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	8.08317e-55
LR134303.1\|VEE64254.1\|4622761_4623550_-\|GTPase-Era	gnl\|CDD\|206648	cd00882, Ras_like_GTPase, Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases). Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.	1.63238e-18
LR134303.1\|VEE64247.1\|4616743_4617703_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.6891e-66

>LR134303.1|VEE64256.1|4624494_4624833_-|Uncharacterized-conserved-protein
MMTPNYSSQFSTSMFWSSLAKDMKRLGRKSLLLALKLYYAAQDPATPVWAKGIIFSALGYLISPIDSIPDMLPVIGLTDDLAVLTAALATVAAHVTESHRLKAEARLQAMFD
>LR134303.1|VEE64255.1|4623549_4624431_-|GTPase-Era
MMNNIIAILQDLDSQLAPAQVERIREKLTSMLNYRPRIGVFGKTGVGKSSLCNALFGKPICAISDIEACTRDPQEVMLNMENGKGITLLDVPGVGENLQRDEEYSELYRKLLPELDMVLWVLKADDRAYSVDIEFYTNVVKPHLQQGKPFILVLNQVDKIEPFRDWDGENRKPGPSQAQNIALKAANVATHFQVKQSLVVPVSADEKFGLTKLVDEIIFSLPDEKKVSIAREVPAENLSTESKAEVKNSLSRVLTRTLTGVATGAALGSKIAGKAGAVVGGVIGGIGGFLGLW
>LR134303.1|VEE64254.1|4622761_4623550_-|GTPase-Era
MKPTLRCTVKIERDVVALVQARNAFGFLHNRQPLLSLASRWQRGDSLSHDIQVIAIGKSGYGKSTTLNQLVGEAVFETNAIAGCTREMQSAEYRFPTKEAQCHFSLADLPGIGEHPELDKQYIQLYRDAIAKAHSVIYFLRADQRDYVIDQWAFAQLFNTDAERRKVIIALNAVDKIEPLNRSQPFALTAEQIQSLRLKRHTICQQFAVCEDQIVTLSATEQHNLDGLVDRLADVLQPYLSQADTTSAYQAHWTSSVNGATY
>LR134303.1|VEE64253.1|4622462_4622765_-|putative-CRISPR-associated-protein,-VVA1548-family
MNKRIWLVSRHPGAQTWLKQQGFQGQQIAHLDIDTIAAGDIIIGSLPIHMVVALTLKNAEYWHLSMTIPECWRGTELTPEQMQLCQIKLQKITAQAEDFF
>LR134303.1|VEE64252.1|4621864_4622155_-|Uncharacterised-protein
MMSSSSPYIFGQQANSQWQKRPLGRVGDLQGWHQRMKALCPNPRLGQVVWLENNHWDNGEGQYVHSSTGYKVINFRANGDPVWERGQVIILSTDDE
>LR134303.1|VEE64251.1|4619619_4621851_-|Probable-ATP-dependent-helicase-dinG-homolog
MLNYQDNNPTQQHSIDIAEVKLANAKLWQAQSQQLYTTLSQAIAGFKSRAGQQQIVELCANNSAQHGQLVVEAGTGVGKTFGYILGHLPAILQNEQRLLISTNTITLQNQLMEKDLPQLLAILAPELTYTIAKSGSRYLCPAKVRSLLTKTEKNTDADSTDDMFDSASPVNMSSAQLQCLKEVYTLFTEGNFAGDLDQLQVANAPQYQKLLNRDQQRCPGQRGCSDGKQCPFYLQREKISKTDIVVTNHAFLVNVLMHDSNAFGDLTNTMLVLDEAHHLPKVIRDVNQAELDLSQAAEIADQFDKLEKASNKLIKTQPALFDDINKFTTSIQRLKPAITDFCEQLQQLNEHMSLNFMAYRGKKQNSFDDIEQWLMSYAPMPISFVTPLLNLYQSCATARTYVEQLNGQFRQQLDNKDIPQAAENACNRWLQSSANLLAMVAQAHHCLDYYYQFTNQQTEDQRLDVGIARWVKNDAATDKITLLANVIDVSQHFQLRIAQAFKSQVLTSATLKTLGSFNHINRQLGINSETSIHADIPSDFNYRHAFLSWAPSNAPEPNNEHFIGYLTQQIMELTQRHSAILVIFTAHNMLESTFNLMPTALKQQILCQDKRSKSELIQEHKRRIDAGQTSILFGVDSLSEGLDLQGKYLTGVVIAKLPFPSLSEPLINYEKITLDARGINSFAQMMVPECSRKLIQSVGRLIRSEQDWGEVFIADRRIQPRPFSNYYGNILLNALPIFQQGVR
>LR134303.1|VEE64250.1|4619031_4619619_-|Helix-destabilizing-protein
MTTGINKVILIGHLGKAPEIKTLNDGVRLCNLSLATSERWTNKQTGQAQEHTEWHRLVLSDRLAEIAEKYLQKGSKIYIEGKLRTRKWQNQLGQEQYTTEVRVAQLQILSSRAQEATKTAEDYSKAVSPVQPVSPVQQVSPTITKLQPIRRMLTILTWMIGTIFLFEVVRHGTISLGNSIVNHSIMWKSKPHLGG
>LR134303.1|VEE64249.1|4618008_4619031_-|Uncharacterized-protein-conserved-in-bacteria
MSQDILWQARNEIIALSAEVGIDGSALLNALPSSSQLLTGSQVPTLSPRYRGKCSVLFHIHQMRNGKSWPWMRLHTFKHGGISRVFNGLQWQRQNSATHWPITPHFGQSNTVSTPQPPSASATLADWRATRFASLQVQYQALPTLTPTHPWLQQRFAAQLPSAVLQRCHLRGNHQQLLLPLQHHHGEISGFQLLTWGENAQKRFWLRRQGLLTGSYALISGQPGPVALCEGLATALSIALAWPGKIYIGLCANNLAAVRAKITGKVVIFYDNDNWKPDYGNPGQQAALACRQTRDILVGPQFSSEQQQTKPTDFNDLHNLAGIAELMHQIRRHWTVKSSY
>LR134303.1|VEE64248.1|4617706_4617985_-|CRISPR-associated-protein-Cas2
MMKQQNILIAYDIQSDNARSCALYNLRKFAISYQDSVFELQLSAAKLQRLILKLQPYISTNDTLLSVHFSPNACWQLGCGLPSISGQFLVIG
>LR134303.1|VEE64247.1|4616743_4617703_-|CRISPR-associated-endonuclease-Cas1
MTTLILEKHGISLEYDTDVLVIREAEMPPRTIPLSRIDKVVCLHNTALSTQLLGQLHQRGIDFIVLNSRYTDHCVALYADTHGNCLRRAAQYTLQLDNKERLPLAKSLCHHKLQQSLRVLDAQQPGRLQSQLQMAQESVRNCQDEQQLRGLEGSAQRALFQHWRQQLDPKWGFERRERRPPPDPVNGLLSLTYTLVHHEAIRQCKQYGLDSTLGIYHRMAYGRHSLACDLMEPTRPIIEQWLVQLLDTDLLTQRHFTKGKPGCYLGKEGRLLFYPQLETQMALIRRKLAANARWMVQQLDHGLTQGQYTLSEASAYELN
>LR134303.1|VEE64258.1|4626828_4627335_-|Uncharacterised-protein
MNTRVLTRQSAMLHYLEQVWQLLQDSYADVPGGLHFASRQQLLETTVRWKLVLQDKQLLAVTVYKAKKGLKLVAMGINQGLQALGKAALILIIKQDLPSCWMELSEKAERFVLKYCDGHNYIIHSSLVAQLLDKPITPHDADSYHYCRFVQQLMKVKIALGSPQLTQS
>LR134303.1|VEE64259.1|4627641_4628913_-|CRISPR-associated-protein,-NE0113-family
MKHILLAVSGMTPQIITETLYGIYKKDCSQMPTEIHVITTGAGSDKLINALMGSDNKLEQFCRDYQLPQILFTEEHIHIPKGDDGLKIVDVRSEREQEIIADFITQFVRDKTTQADIAIHASLAGGRKTMGFAMGYAMSLFGRHQDSLSHVLVSEPYEIVPDFFYPTPQETWRADKNGSRHDMSKAEVTLATIPLVLMREEMPTALLSNTQLSYTETVSRVNKANALNAEDASVILDYQRLTINCDGYEVAMKPDCFAFYSWLAQDSKENPGEGTEAPCSGMKCGELNQRLRKFYLALLPPQWVLRDEYTEISLEELAEVTKDHLDRLEPQPKSSWLLQDNDNTQQLLNADADTCDAELVKKHNTLWHRLLRETNKALEDVMGKKLAKFYQIQTVNHVKGSVKTAVQDFKGLAIQAHKIQFID
>LR134303.1|VEE64260.1|4629041_4630235_-|Domain-of-uncharacterised-function-(DUF1887)
MKTIHINLVSEQLIPNLISTLGDENCCGVVLVLGDSKFADKADRLENLYKRNQLKVLWRSQGMSSTRLPQLQTQANALIDYLATNHSDCHWVLNATCGTKPMALAFANAFNQQDKQQALVIYTDTEHKEIPLLNPGVDFTLPFKSVLSLDDYLLANGFEYEQAINSDNDAQLQQHAPLTRYLAQQLVGKCQHMLGSLQSMATIAAKDFPHSQIQTMPSVPHGDYAKLYLRLNDEGLLSWDGQCKQITFQSEDACRYLAGRWLEEFTYLTALECGAKEVAMSVTGRWLQDSRNFGSDDLTNEFDVLILHNNQLLTIECKASNWFRQEEHGSKNQDIIHKLDTLSKNLGGLFGSPMLVTAQQLSDAARSRVTYNRFRCCEQATEKSLKKALCAWVGTVG
>LR134303.1|VEE64261.1|4630313_4631192_-|Uncharacterized-conserved-protein-(DUF2276)
MTPPTVLLDLAEQFEILHLRCNLILQADGVLPAFKGSLWHGWLGHAIKGLDEPLYQLLYGSHAEQQPKPYLIKAGADHKQQWRAGEMLEFDIILLGSACQLGQRLVSALLSGQRLGLGTNRIPFRVQSLTSVLPMRQTPGLHVARLIDWLMPMDVGLDCEIALQLHSPLRLKQNGNIIKSATPALPELIKQISRRMALLTLFWVNEDPCLQAALFKTLPILGDYQSDGSHVWFEDWQRYSARQHEQLPFGGLKGQLCYRGDLSAAIPWLQLGELLHMGGKTTFGLGQYRLIY
>LR134303.1|VEE64262.1|4631188_4633483_-|CRISPR-associated-protein
MSSQVHAPYHFAPLSSWVYMPEWAHLVSHDHPFEDSLSGVIEYELTNKTPLLVGGEQLRADNQPSKILWSRDPDGKPVIPGSSVKGMLRSVLEIASFAKFSMVDDHHFGFRDISNSDSRYAQKVLDRETETQTYWLKYDADRCQWMLRKCQHTVLFTDDFNQFSGLRFHNQSFKLPAKEKYEQWPLNKPAIPFELGTRTMMGTKGKPVTITCAQQLGTGKLAGVPVFTGSRPGKNEVKEQRLNFNYVFYAHEAEAKPLDNGAAKVTKMFAAHDEDLVNHLKKFGHPELGMPIFAKEKQGKIIAMGFAKMPKVLYDNSIGDIANKQQKPLNSQSVFDMPGLMFGTLAESGFSLKSRVAFSDASCSHNAGITLSKPVILGQPKASYLNAYLEQNAQSDRVRGELSQYENNSKLAGWKRYPAQSGFNAHLPADLARKTSVQSQLELMNPGSRFNGKLVFHNLKPVELGALLWVLNPDGDKRVFHHALGHGKSLGAGAVQFNAKITIAHSDLTPELNELRSLFVEHMNAVYPSSQPTASSWLLSPQIRHLLAFGDRGDNQNKDLSYMQLNSKDSQEITYTSSAKGREKLVLPAFCHQSDALGRNEQLKQSAPQLGRGRLYQLLEQLEKTDNISEFEREQLEQSKQAAEQAAKNALFAQASPQYREYLNIIDELTPYRNQSNVDADNKRQGMRGRIDSLLTNCLSNENEADETELQQICRFVFDFPFSGYIDPSIKRKDLSKKAKEKFDERKALVDALLGKCKLEAADI
>LR134303.1|VEE64263.1|4633484_4634006_-|Uncharacterised-protein
MSNSETMTIYNTLASKSYTEPELLGCALPTLYGGRIEAQHQICNRDELKLMLAQWQDAEGWYQSRADVGLGMPVNLDELLEGQWHRADQSLHLELRSDQTYNLTLFIQHEVSQGQLARQCYSDQLIFLRPSLKSQNQTLRYRIWWQQAETGPNEGGWRPLLQQFLGLAQQKEQ
>LR134303.1|VEE64264.1|4634009_4635419_-|CRISPR-associated-RAMP-protein,-SSO1426-family
MSQMYLTRLLIETTAPLAINSGGRETGFDSQLARDANQLPYIPASSLAGVWRHLVHSCVGADASKRWFGCIDDNGESSRLFVQDGLLLDSQGHIVQGLVEAERIAADPLLQRLQQTRPHHRERVRINDRGVASDLGKFDQIILPTGIRFCIDIRWMSDDVSENDRQEWQQLLSYFSHPAFALGSSTRNGLGRFKIIADEQNILTLTNNPSAGAALRKFVKRETLPTKVSSITNDYRPFARLELTALDSWRCGQGSRPLGDKTDQHTDSFTYSEPTVRWHKGKAHWNDKPQAILCGSGIKGILAHRLAYHYRRRKGAFAEIMAEASHQEWESRPQELGQLLGSSREKNGAGSSEQEVAGQLFVDDAVIVCDKTLIRTHNSIDRFTGGVRQGALFSEELLWQPKIALTLRLASNAKISQTLADALADTLEDLKLGLLPLGAGSGRGNSLVEHQTGQIWDIDWAQLTILAQE
>LR134303.1|VEE64265.1|4635421_4636954_-|CRISPR-associated-RAMP-protein,-Csx10-family
MRLYFSLTNLEPLVISQSSASTNNHQCLDHIPGSAILGAIASKLYSSLSAEQSFALFHSGACRFGPAYPIHNDEIAMPIPASWHKIKNDGHTLYNHAAANFSRDKAKQYQQCRNGYITSKSIDVFVKQGLTTRTAIDEQTQRASDGQLYSYAFIEAGQHFGAWVDVNDSSLLAILRPLLNGELNIGRSRSSEFGRVQLHCPTQQPATQQACKLENQLVLWCLSDAECRDEWGMPTVTPRAEDLHPALKGELDTTRSFIRSHKVRRFNRARNGFDTEQQLISRGSILTFTLHETASDDVLREMASQGIGCNRQQGLGWVSANPQWASMAQPNSLAIFDAITLTPPPKQETSGAQTETPLLRWVRVKQQESQTNKDQSTRIKALHQAIYAAYSNARHYRNVPRNYQAGPSSSQWRRLTDLVRSRQDESWFKVAFVSDAAICKSNNDPDGWGIDWQEQGVLLTFSEKMQKIFDGADILLMRQLLEILCRYDLSTSDGLQRFHTNHLAPRKGGE
>LR134303.1|VEE64266.1|4636953_4637553_-|CRISPR-associated-RAMP-protein,-SSO1426-family
MIKSIQVMLTFDLRSEWHLGSGREGGAYADNLVQKNPDGLPIINGKTIKGLLRQAFNDANKYQWFPDADVDTIEHLFGREGTDLIASGALKCDSASLNLAEQHYFKENPSAIGHLYRVRHATAIDPQTGTAQDGSLRAMEVVIPMVMQSRLTLTTDNPKILKQFSKWLDLSLPLLCALGGKRRRGLGEVIVTATGQENY
>LR134303.1|VEE64267.1|4637549_4639274_-|Uncharacterised-protein
MYVYLFEAKSIQTYLFRSGRLKDVISASERLDRLVDDDSGSVLAQVLHSAGLKSDLLESVLVSDQVIGFTRCKGGAFYAYCEQREPLLTLRSLWTLTVQQLFPGLEFADALTQGETLAEAMDAGHPALAASRNCPTVKFPLATAPCDHAPRTGLAAVPLSAAAKTEVKSSEKDERIDLDTEHHRQGYRLLRLRKEPLLHKFITSIEGDKQLPDSLNFPLNMEDFPAFNDPDEGHSVVKDLALIHIDGNGLGLLLRSLQGALKGIGDQEYGRAFRTFSSALARATQQAAFQASYWLYQEQKRGLDAGCEPDMLAMRPIVLGGDDITLFCQADLALGYAETFCIAFKSCSERELAPLYHDYLQGTPLKPYLTASGGILYHKATHPFTTCHNLVEGLCKEAKQLTQSLDSHVGPAAISFYRLSHALAEDIVTLRTQSQQFLIEDRQLLTSIGGYLVEDKTQNNAHKTNTYTPSLSNLKQAITLLRDKRSSLSIAKFRQMATELARGDMDEAERIYERAYEQLSPATLKEWQTILASLFPKADTPNWYWNNKSWLSDLLTIAHFLPQSTTSVTQGSKK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134303_4	4.13\|4626169\|34\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4626169-4626202	34	MN582077	Podoviridae sp. ctLUJ1, complete genome	13269-13302	0	1.0
LR134303_4	4.16\|4626380\|33\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4626380-4626412	33	MN582077	Podoviridae sp. ctLUJ1, complete genome	13120-13152	3	0.909
LR134303_3	3.19\|4615323\|31\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4615323-4615353	31	NC_047960	Enterobacteria phage vB_EcoS_IME347, complete genome	9292-9322	5	0.839
LR134303_3	3.7\|4614483\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614483-4614514	32	NC_027625	Propionibacterium phage Kubed, complete genome	8623-8654	6	0.812
LR134303_3	3.7\|4614483\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614483-4614514	32	NC_022340	Propionibacterium phage PHL114L00, complete genome	8622-8653	6	0.812
LR134303_3	3.7\|4614483\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614483-4614514	32	KJ578775	Propionibacterium phage PHL114N00, complete genome	8622-8653	6	0.812
LR134303_3	3.11\|4614765\|33\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614765-4614797	33	NZ_AP017309	Leptolyngbya sp. NIES-3755 plasmid plasmid1 DNA, complete genome	41018-41050	6	0.818
LR134303_4	4.9\|4625890\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4625890-4625921	32	MF370965	Pseudoalteromonas phage SL25, complete genome	31808-31839	6	0.812
LR134303_3	3.4\|4614272\|34\|LR134303\|CRISPRCasFinder,CRT	4614272-4614305	34	NZ_CP033067	Pseudoalteromonas agarivorans strain Hao 2018 plasmid unnamed, complete sequence	39862-39895	7	0.794
LR134303_3	3.7\|4614483\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614483-4614514	32	NC_011561	Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2 plasmid pCFPG2 DNA, complete sequence	18306-18337	8	0.75
LR134303_3	3.18\|4615255\|31\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4615255-4615285	31	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	796506-796536	8	0.742
LR134303_3	3.31\|4616163\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4616163-4616194	32	CP000620	Burkholderia vietnamiensis G4 plasmid pBVIE04, complete sequence	82074-82105	8	0.75
LR134303_4	4.9\|4625890\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4625890-4625921	32	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	2257422-2257453	8	0.75
LR134303_3	3.7\|4614483\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614483-4614514	32	NC_020865	Cyanophage KBS-P-1A genomic sequence	14211-14242	9	0.719
LR134303_3	3.7\|4614483\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4614483-4614514	32	HQ317389	Synechococcus phage S-RIP2 genomic sequence	4195-4226	9	0.719
LR134303_3	3.3\|4614203\|32\|LR134303\|CRISPRCasFinder,CRT	4614203-4614234	32	NZ_CP048417	Citrobacter freundii strain CitB plasmid pA_CitB, complete sequence	79497-79528	10	0.688
LR134303_3	3.31\|4616163\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4616163-4616194	32	MN692999	Marine virus AFVG_117M75, complete genome	53757-53788	10	0.688
LR134303_4	4.9\|4625890\|32\|LR134303\|CRISPRCasFinder,CRT,PILER-CR	4625890-4625921	32	NC_049805	Lactococcus phage phiQ1 DNA, complete genome	21438-21469	10	0.688
LR134303_3	3.4\|4614272\|34\|LR134303\|CRISPRCasFinder,CRT	4614272-4614305	34	AP014258	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S27-C55, * SEQUENCING IN PROGRESS *	9704-9737	11	0.676

1. spacer 4.13|4626169|34|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to MN582077 (Podoviridae sp. ctLUJ1, complete genome) position: , mismatch: 0, identity: 1.0

gaagtatgaacaagagaagtctacttggaatatc	CRISPR spacer
gaagtatgaacaagagaagtctacttggaatatc	Protospacer
**********************************

2. spacer 4.16|4626380|33|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to MN582077 (Podoviridae sp. ctLUJ1, complete genome) position: , mismatch: 3, identity: 0.909

gtagtacgtgtattcagtactattgataaaaca	CRISPR spacer
gtagtacgtgtattcagtactatcgataagact	Protospacer
***********************.*****.**

3. spacer 3.19|4615323|31|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NC_047960 (Enterobacteria phage vB_EcoS_IME347, complete genome) position: , mismatch: 5, identity: 0.839

aaaaaagttgtcatcgttaaatctccgtaat	CRISPR spacer
aaaaaagttgtcatggttaaatttcccttac	Protospacer
************** *******.*** * *.

4. spacer 3.7|4614483|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NC_027625 (Propionibacterium phage Kubed, complete genome) position: , mismatch: 6, identity: 0.812

gtagagttcttcccaaaagcaaacaaaccacc	CRISPR spacer
gccaacttcatcccagaagcaaacaaaccacc	Protospacer
*. .* *** *****.****************

5. spacer 3.7|4614483|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NC_022340 (Propionibacterium phage PHL114L00, complete genome) position: , mismatch: 6, identity: 0.812

gtagagttcttcccaaaagcaaacaaaccacc	CRISPR spacer
gccaacttcatcccagaagcaaacaaaccacc	Protospacer
*. .* *** *****.****************

6. spacer 3.7|4614483|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to KJ578775 (Propionibacterium phage PHL114N00, complete genome) position: , mismatch: 6, identity: 0.812

gtagagttcttcccaaaagcaaacaaaccacc	CRISPR spacer
gccaacttcatcccagaagcaaacaaaccacc	Protospacer
*. .* *** *****.****************

7. spacer 3.11|4614765|33|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP017309 (Leptolyngbya sp. NIES-3755 plasmid plasmid1 DNA, complete genome) position: , mismatch: 6, identity: 0.818

gaagtatctttagcaatcgctcaacgtaaatca	CRISPR spacer
tcagactctttagcaatcgctcaacgtaaattt	Protospacer
  **  *************************.

8. spacer 4.9|4625890|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to MF370965 (Pseudoalteromonas phage SL25, complete genome) position: , mismatch: 6, identity: 0.812

atttcattggcttcttcaataacctttttagt	CRISPR spacer
tctgccttagcttcttcaatagcctttttagt	Protospacer
 .* * **.************.**********

9. spacer 3.4|4614272|34|LR134303|CRISPRCasFinder,CRT matches to NZ_CP033067 (Pseudoalteromonas agarivorans strain Hao 2018 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

aagaatccaaagcaagaaaggttaatagctaatc	CRISPR spacer
aactatccaaagaaataaaggttaatagctatag	Protospacer
**  ******** ** ***************

10. spacer 3.7|4614483|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NC_011561 (Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2 plasmid pCFPG2 DNA, complete sequence) position: , mismatch: 8, identity: 0.75

gtagagttcttcccaaaagcaaacaaaccacc	CRISPR spacer
ttagcattcttcccaaaagcaaacaacagtgc	Protospacer
 *** .********************     *

11. spacer 3.18|4615255|31|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 8, identity: 0.742

tgcgcaggtgctgttttgatgatttattcgc	CRISPR spacer
acagcagctgctgctttgatgatttatgctg	Protospacer
   **** *****.************* *

12. spacer 3.31|4616163|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to CP000620 (Burkholderia vietnamiensis G4 plasmid pBVIE04, complete sequence) position: , mismatch: 8, identity: 0.75

aaatacc----ctgaataccaagaaaaagaaagata	CRISPR spacer
----accatgactgaataccatgaagaagaaagagc	Protospacer
    ***    ********** ***.********

13. spacer 4.9|4625890|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

atttcattggcttcttcaataacctttttagt	CRISPR spacer
gctatattggcttcttctttaacctttttgat	Protospacer
..* .************  **********..*

14. spacer 3.7|4614483|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NC_020865 (Cyanophage KBS-P-1A genomic sequence) position: , mismatch: 9, identity: 0.719

gtagagttcttcccaaaagcaaacaaaccacc	CRISPR spacer
ttagagttctacacaaaagcaaacggaagctc	Protospacer
 ********* * ***********..*   .*

15. spacer 3.7|4614483|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to HQ317389 (Synechococcus phage S-RIP2 genomic sequence) position: , mismatch: 9, identity: 0.719

gtagagttcttcccaaaagcaaacaaaccacc	CRISPR spacer
ttagagttctacacaaaagcaaacggaagctc	Protospacer
 ********* * ***********..*   .*

16. spacer 3.3|4614203|32|LR134303|CRISPRCasFinder,CRT matches to NZ_CP048417 (Citrobacter freundii strain CitB plasmid pA_CitB, complete sequence) position: , mismatch: 10, identity: 0.688

gtagtagtttcagcatcatggctactcgaact	CRISPR spacer
cggttagtttcagcatcatgccttctccttcg	Protospacer
  . **************** ** ***   *

17. spacer 3.31|4616163|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to MN692999 (Marine virus AFVG_117M75, complete genome) position: , mismatch: 10, identity: 0.688

aaataccctgaataccaagaaaaagaaagata	CRISPR spacer
gctctggctgaataccaagaaatggaaagaca	Protospacer
.  .   *************** .******.*

18. spacer 4.9|4625890|32|LR134303|CRISPRCasFinder,CRT,PILER-CR matches to NC_049805 (Lactococcus phage phiQ1 DNA, complete genome) position: , mismatch: 10, identity: 0.688

atttcattggcttcttcaataacctttttagt	CRISPR spacer
caatcactggtttcttcaataaccttcctctc	Protospacer
   ***.***.***************..*  .

19. spacer 3.4|4614272|34|LR134303|CRISPRCasFinder,CRT matches to AP014258 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S27-C55, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 11, identity: 0.676

aagaatccaaagcaagaaaggttaatagctaatc	CRISPR spacer
cctaatccaaaccaagaaaggctaatatgataca	Protospacer
   ******** *********.*****    *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1915328 : 1927825

Bacillus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE61951.1\|1915328_1920212_-	Signal transduction histidine-protein kinase BarA	A0A1V0SGX0	Hokovirus	2.9e-66	30.6
VEE61952.1\|1920580_1921306_+	Transcriptional regulatory protein OmpR	W8CYM9	Bacillus_phage	4.9e-31	34.7
VEE61953.1\|1921345_1922662_+	Osmolarity sensor protein EnvZ	W8CYF6	Bacillus_phage	7.8e-11	22.5
VEE61954.1\|1922778_1924755_+	H3	A0A2H4J162	uncultured_Caudovirales_phage	6.0e-15	54.3
VEE61955.1\|1924811_1925285_-	Hybrid peroxiredoxin hyPrx5	M1I839	Pelagibacter_phage	1.4e-23	49.1
VEE61956.1\|1925546_1926479_-	Uncharacterised protein	NA	NA	NA	NA
VEE61957.1\|1926837_1927140_+	Uncharacterised protein	NA	NA	NA	NA
VEE61958.1\|1927141_1927825_+	Transcriptional regulatory protein phoP	Q6XM27	Feldmannia_irregularis_virus	1.4e-06	26.5

DBSCAN-SWA_2

3469263 : 3476707

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE63268.1\|3469263_3470931_-	Uncharacterized ABC transporter ATP-binding protein HI_1252	A0A1V0SKJ1	Klosneuvirus	8.6e-39	27.6
VEE63269.1\|3471121_3472375_+	Pyridoxal-phosphate-dependent serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	4.6e-101	53.1
VEE63270.1\|3472585_3473035_+	Transcriptional repressor NrdR	NA	NA	NA	NA
VEE63271.1\|3473110_3474256_+	Riboflavin biosynthesis protein RibD	A0A1V0SE20	Indivirus	5.7e-50	34.9
VEE63272.1\|3474263_3474920_+	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	8.7e-27	34.0
VEE63273.1\|3474987_3476091_+	Riboflavin biosynthesis protein ribBA	A0A2H4PQS2	Staphylococcus_phage	5.8e-68	39.7
VEE63274.1\|3476230_3476707_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.0e-29	45.7

DBSCAN-SWA_3

3498282 : 3510042

uncultured_Mediterranean_phage(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE63291.1\|3498282_3499578_+	Enolase	A0A1X9I5Z8	Streptococcus_phage	4.0e-132	58.7
VEE63292.1\|3499621_3499978_+	Cell division protein FtsB	NA	NA	NA	NA
VEE63293.1\|3499988_3500738_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
VEE63294.1\|3500789_3501269_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
VEE63295.1\|3501298_3502426_+\|tRNA	tRNA pseudouridine synthase D	NA	NA	NA	NA
VEE63296.1\|3502422_3503172_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	5.9e-72	52.7
VEE63297.1\|3503168_3503804_+	Protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	9.9e-36	51.2
VEE63298.1\|3503902_3504799_+	Murein hydrolase activator NlpD precursor	I3PV79	Clostridium_phage	2.6e-10	31.0
VEE63299.1\|3504879_3505860_+	RNA polymerase sigma factor rpoS	F4YCU2	Synechococcus_phage	1.4e-33	32.9
VEE63300.1\|3506000_3508586_-	DNA mismatch repair protein mutS	A0A1V0SC35	Catovirus	2.5e-29	23.1
VEE63301.1\|3508968_3510042_+	Recombinase A	A0A2D1GPX2	Mycobacterium_phage	2.9e-112	62.2

DBSCAN-SWA_4

4687569 : 4698866

uncultured_Caudovirales_phage(28.57%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE64310.1\|4687569_4690314_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	4.2e-83	47.7
VEE64311.1\|4690383_4691004_+	P20	NA	NA	NA	NA
VEE64312.1\|4691012_4692344_+	Replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.4e-76	39.6
VEE64313.1\|4692336_4692711_+	camphor resistance protein CrcB	A0A2H4PQR0	Staphylococcus_phage	3.5e-09	37.4
VEE64314.1\|4692729_4694016_+\|tRNA	Serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.8e-99	45.3
VEE64315.1\|4694224_4694563_-	Sulfurtransferase TusE	NA	NA	NA	NA
VEE64316.1\|4694556_4694838_-\|tRNA	tRNA 2-thiouridine synthesizing protein B	NA	NA	NA	NA
VEE64317.1\|4694837_4695194_-\|tRNA	tRNA 2-thiouridine synthesizing protein C	NA	NA	NA	NA
VEE64318.1\|4695208_4695601_-	Sulfurtransferase TusD	A0A2H4JA39	uncultured_Caudovirales_phage	1.5e-21	43.3
VEE64319.1\|4695657_4696317_-\|protease	Modulator of FtsH protease YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	1.1e-34	44.3
VEE64320.1\|4696576_4697479_-	HTH-type transcriptional activator AllS	NA	NA	NA	NA
VEE64321.1\|4697594_4698866_+	Inner membrane transport protein ydhC	S4TR35	Salmonella_phage	2.9e-18	22.8

DBSCAN-SWA_5

4943792 : 4954010

Yellowstone_lake_phycodnavirus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE64539.1\|4943792_4945511_+	Acetolactate synthase isozyme 3 large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	2.8e-56	30.2
VEE64540.1\|4945510_4946005_+	Acetolactate synthase isozyme 3 small subunit	NA	NA	NA	NA
VEE64541.1\|4946137_4946581_-	16 kDa heat shock protein A	A0A2L0V0Y9	Agrobacterium_phage	1.8e-20	49.5
VEE64542.1\|4946884_4947316_-	Nucleoside diphosphate kinase	K7YW26	Megavirus	2.8e-18	40.9
VEE64543.1\|4947536_4947704_-	Uncharacterised protein	NA	NA	NA	NA
VEE64544.1\|4947901_4948099_-	FeS assembly protein IscX	NA	NA	NA	NA
VEE64545.1\|4948167_4949067_-	Alpha-aminoadipate--lysW ligase lysX	I3ULC9	Synechococcus_phage	3.2e-40	33.2
VEE64546.1\|4949222_4949558_-	2Fe-2S ferredoxin	NA	NA	NA	NA
VEE64547.1\|4949566_4951429_-	Hsc66	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.0e-104	39.0
VEE64548.1\|4951496_4952021_-	Co-chaperone protein hscB homolog	NA	NA	NA	NA
VEE64549.1\|4952036_4952360_-	Iron-sulfur cluster assembly protein	A0A2H4N7N5	Lake_Baikal_phage	4.1e-22	43.0
VEE64550.1\|4952374_4952758_-	NifU-like protein	A0A218MKD1	uncultured_virus	1.0e-51	77.4
VEE64551.1\|4952795_4954010_-	Cysteine desulfurase	A0A0H3TPH2	Faustovirus	6.7e-33	31.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134303

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection