CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134305	Staphylococcus aureus strain NCTC1803 genome assembly, chromosome: 1	8 crisprs	cas3,DEDDh,DinG,csa3,WYL	6	2	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134305_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_2

620185-620266

Orphan

Consensus_repeat	Method
CAATTTCTACAGGCAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134305_2

>merge|LR134305|2|620185-620266|CRISPRCasFinder
CAATTTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACACAGAGAAATTGGGGAGTCAATTTCTACAGACAATGCAAGTTGG

>LR134305|2|1|620185-620266|CRISPRCasFinder
CAATTTCTACAGGCAATGCAAGTTGG	CGGGGCCCCAACACAGAGAAATTGGGGAGT
CAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE67762.1\|610559_610901_-\|Na+/H+-antiporter-subunit	unknown	unknown	gnl\|CDD\|181497
LR134305.1\|VEE67774.1\|624518_625850_+\|Glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
LR134305.1\|VEE67773.1\|622963_624169_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
LR134305.1\|VEE67761.1\|609070_610567_-\|Na(+)-H(+)-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
LR134305.1\|VEE67769.1\|617486_618677_+\|Ornithine-aminotransferase	unknown	unknown	gnl\|CDD\|179736
LR134305.1\|VEE67775.1\|626721_627297_+\|SNARE-associated-Golgi-family-protein	unknown	unknown	gnl\|CDD\|223475
LR134305.1\|VEE67766.1\|614304_614898_+\|Peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
LR134305.1\|VEE67777.1\|627841_628417_+\|Signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
LR134305.1\|VEE67765.1\|613857_614241_-\|kinase-associated-B-family-protein	unknown	unknown	gnl\|CDD\|378054
LR134305.1\|VEE67763.1\|610900_611329_-\|Na(+)-H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
LR134305.1\|VEE67778.1\|628576_632053_+\|helicase-exonuclease-AddAB,-AddB-subunit	unknown	unknown	gnl\|CDD\|213736
LR134305.1\|VEE67772.1\|621594_622974_-\|Argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
LR134305.1\|VEE67780.1\|635872_636775_+\|Fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
LR134305.1\|VEE67771.1\|620423_621353_-\|putative-glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
LR134305.1\|VEE67770.1\|618785_620030_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
LR134305.1\|VEE67768.1\|616051_617179_+\|Putative-NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
LR134305.1\|VEE67779.1\|632053_635707_+\|ATP-dependent-nuclease,-subunit-A	unknown	unknown	gnl\|CDD\|274299
LR134305.1\|VEE67767.1\|615313_615691_+\|general-stress-protein-13	unknown	unknown	gnl\|CDD\|224023
LR134305.1\|VEE67764.1\|611321_613727_-\|Na(+)-H(+)-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
LR134305.1\|VEE67776.1\|627301_627826_+\|Signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE67762.1\|610559_610901_-\|Na+/H+-antiporter-subunit	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64
LR134305.1\|VEE67774.1\|624518_625850_+\|Glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
LR134305.1\|VEE67773.1\|622963_624169_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
LR134305.1\|VEE67761.1\|609070_610567_-\|Na(+)-H(+)-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
LR134305.1\|VEE67769.1\|617486_618677_+\|Ornithine-aminotransferase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
LR134305.1\|VEE67775.1\|626721_627297_+\|SNARE-associated-Golgi-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	3.53252e-40
LR134305.1\|VEE67766.1\|614304_614898_+\|Peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
LR134305.1\|VEE67777.1\|627841_628417_+\|Signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
LR134305.1\|VEE67765.1\|613857_614241_-\|kinase-associated-B-family-protein	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
LR134305.1\|VEE67763.1\|610900_611329_-\|Na(+)-H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
LR134305.1\|VEE67778.1\|628576_632053_+\|helicase-exonuclease-AddAB,-AddB-subunit	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
LR134305.1\|VEE67772.1\|621594_622974_-\|Argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
LR134305.1\|VEE67780.1\|635872_636775_+\|Fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
LR134305.1\|VEE67771.1\|620423_621353_-\|putative-glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.0773e-151
LR134305.1\|VEE67770.1\|618785_620030_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
LR134305.1\|VEE67768.1\|616051_617179_+\|Putative-NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
LR134305.1\|VEE67779.1\|632053_635707_+\|ATP-dependent-nuclease,-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
LR134305.1\|VEE67767.1\|615313_615691_+\|general-stress-protein-13	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
LR134305.1\|VEE67764.1\|611321_613727_-\|Na(+)-H(+)-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
LR134305.1\|VEE67776.1\|627301_627826_+\|Signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.90097e-49

>LR134305.1|VEE67770.1|618785_620030_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>LR134305.1|VEE67769.1|617486_618677_+|Ornithine-aminotransferase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>LR134305.1|VEE67768.1|616051_617179_+|Putative-NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNDAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIKQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>LR134305.1|VEE67767.1|615313_615691_+|general-stress-protein-13
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>LR134305.1|VEE67766.1|614304_614898_+|Peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>LR134305.1|VEE67765.1|613857_614241_-|kinase-associated-B-family-protein
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>LR134305.1|VEE67764.1|611321_613727_-|Na(+)-H(+)-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIHGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>LR134305.1|VEE67763.1|610900_611329_-|Na(+)-H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>LR134305.1|VEE67762.1|610559_610901_-|Na+/H+-antiporter-subunit
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>LR134305.1|VEE67761.1|609070_610567_-|Na(+)-H(+)-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPLRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>LR134305.1|VEE67771.1|620423_621353_-|putative-glycerophosphoryl-diester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGRVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>LR134305.1|VEE67772.1|621594_622974_-|Argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>LR134305.1|VEE67773.1|622963_624169_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAIECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFVKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>LR134305.1|VEE67774.1|624518_625850_+|Glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>LR134305.1|VEE67775.1|626721_627297_+|SNARE-associated-Golgi-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLALSKLVSTIILGYLGKEITTILTHPLRGIIMLVVLIVFWIVGKKLEQHFMGSKKE
>LR134305.1|VEE67776.1|627301_627826_+|Signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLVDKKDIIGNISLTYYPFSKWTIQFKS
>LR134305.1|VEE67777.1|627841_628417_+|Signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>LR134305.1|VEE67778.1|628576_632053_+|helicase-exonuclease-AddAB,-AddB-subunit
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQNTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDLLNQGLDYLMSALTFDNETVKLGETLSKELYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNINIDDEFGGEQ
>LR134305.1|VEE67779.1|632053_635707_+|ATP-dependent-nuclease,-subunit-A
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVNYDESAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSKLYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>LR134305.1|VEE67780.1|635872_636775_+|Fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: LR134305_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_4

752393-752489

Orphan

Consensus_repeat	Method
GCATAAAAGCCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134305_4

>merge|LR134305|4|752393-752489|CRISPRCasFinder
GCATAAAAGCCCCTAACAACTAAAAGTTGTAAGGTAAAAGAGGGATACTTGCGCTGAGCGCATGCATAAAAGCCCCTAACAACTAAAGGTTGTAAGG

>LR134305|4|3|752393-752489|CRISPRCasFinder
GCATAAAAGCCCCTAACAACTAAAAGTTGTAAGG	TAAAAGAGGGATACTTGCGCTGAGCGCAT
GCATAAAAGCCCCTAACAACTAAAGGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE67890.1\|755729_756272_+\|Radical-activating-enzyme-protein	unknown	unknown	gnl\|CDD\|368297
LR134305.1\|VEE67892.1\|756694_758413_+\|Phosphoenolpyruvate-protein-phosphotransferase-of-PTS-system	unknown	unknown	gnl\|CDD\|224006
LR134305.1\|VEE67894.1\|759078_760440_+\|Cytochrome-d-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
LR134305.1\|VEE67885.1\|749923_751324_-\|Duplicated-ATPase-component-YkoD-of-energizing-module-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	unknown	unknown	gnl\|CDD\|213192
LR134305.1\|VEE67883.1\|747611_748859_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
LR134305.1\|VEE67895.1\|760436_761456_+\|Cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
LR134305.1\|VEE67877.1\|740190_740862_+\|Phosphoribosylformylglycinamidine-synthase	unknown	unknown	gnl\|CDD\|235140
LR134305.1\|VEE67880.1\|744499_745528_+\|Phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
LR134305.1\|VEE67886.1\|751339_751915_-\|Substrate-specific-component-YkoE-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	unknown	unknown	gnl\|CDD\|227065
LR134305.1\|VEE67888.1\|752784_754080_+\|membrane-spanning-protein	unknown	unknown	unknown
LR134305.1\|VEE67891.1\|756425_756692_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
LR134305.1\|VEE67879.1\|743022_744507_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
LR134305.1\|VEE67882.1\|746111_747590_+\|IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
LR134305.1\|VEE67878.1\|740854_743044_+\|Phosphoribosylformylglycinamidine-synthase,-synthetase-subunit	unknown	unknown	gnl\|CDD\|234921
LR134305.1\|VEE67887.1\|752498_752633_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE67896.1\|761588_762251_+\|Trk-system-potassium-uptake-protein-trkA	unknown	unknown	gnl\|CDD\|223643
LR134305.1\|VEE67893.1\|758647_758881_-\|glutaredoxin	unknown	unknown	gnl\|CDD\|239274
LR134305.1\|VEE67889.1\|754503_755676_+\|LSU-m5C1962-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|224017
LR134305.1\|VEE67884.1\|749124_749931_-\|hydroxymethylpyrimidine-transport-system-permease-protein	unknown	unknown	gnl\|CDD\|223692
LR134305.1\|VEE67881.1\|745530_746097_+\|Phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE67890.1\|755729_756272_+\|Radical-activating-enzyme-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00772217
LR134305.1\|VEE67895.1\|760436_761456_+\|Cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.67944e-76
LR134305.1\|VEE67894.1\|759078_760440_+\|Cytochrome-d-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	7.19158e-165
LR134305.1\|VEE67885.1\|749923_751324_-\|Duplicated-ATPase-component-YkoD-of-energizing-module-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	4.90758e-64
LR134305.1\|VEE67883.1\|747611_748859_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
LR134305.1\|VEE67877.1\|740190_740862_+\|Phosphoribosylformylglycinamidine-synthase	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	7.03361e-141
LR134305.1\|VEE67880.1\|744499_745528_+\|Phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
LR134305.1\|VEE67886.1\|751339_751915_-\|Substrate-specific-component-YkoE-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
LR134305.1\|VEE67892.1\|756694_758413_+\|Phosphoenolpyruvate-protein-phosphotransferase-of-PTS-system	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
LR134305.1\|VEE67891.1\|756425_756692_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
LR134305.1\|VEE67889.1\|754503_755676_+\|LSU-m5C1962-methyltransferase-RlmI	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
LR134305.1\|VEE67882.1\|746111_747590_+\|IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
LR134305.1\|VEE67879.1\|743022_744507_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
LR134305.1\|VEE67878.1\|740854_743044_+\|Phosphoribosylformylglycinamidine-synthase,-synthetase-subunit	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
LR134305.1\|VEE67896.1\|761588_762251_+\|Trk-system-potassium-uptake-protein-trkA	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
LR134305.1\|VEE67893.1\|758647_758881_-\|glutaredoxin	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.99976e-16
LR134305.1\|VEE67884.1\|749124_749931_-\|hydroxymethylpyrimidine-transport-system-permease-protein	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.22352e-28
LR134305.1\|VEE67881.1\|745530_746097_+\|Phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	1.72008e-91

>LR134305.1|VEE67886.1|751339_751915_-|Substrate-specific-component-YkoE-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>LR134305.1|VEE67885.1|749923_751324_-|Duplicated-ATPase-component-YkoD-of-energizing-module-of-thiamin-regulated-ECF-transporter-for-HydroxyMethylPyrimidine
MLKVSDLRLKYPNGQRKIFDHLNINIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLENVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>LR134305.1|VEE67884.1|749124_749931_-|hydroxymethylpyrimidine-transport-system-permease-protein
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDVANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDVIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>LR134305.1|VEE67883.1|747611_748859_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVHDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>LR134305.1|VEE67882.1|746111_747590_+|IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGASKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>LR134305.1|VEE67881.1|745530_746097_+|Phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>LR134305.1|VEE67880.1|744499_745528_+|Phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVEEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDKNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGRIVKNESTAIEFLGV
>LR134305.1|VEE67879.1|743022_744507_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>LR134305.1|VEE67878.1|740854_743044_+|Phosphoribosylformylglycinamidine-synthase,-synthetase-subunit
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKNYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKVVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGVLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>LR134305.1|VEE67877.1|740190_740862_+|Phosphoribosylformylglycinamidine-synthase
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELKIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>LR134305.1|VEE67887.1|752498_752633_-|Uncharacterised-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>LR134305.1|VEE67888.1|752784_754080_+|membrane-spanning-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>LR134305.1|VEE67889.1|754503_755676_+|LSU-m5C1962-methyltransferase-RlmI
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>LR134305.1|VEE67890.1|755729_756272_+|Radical-activating-enzyme-protein
MGFKNNLTSNLTNKIGNSVFKIENINEKGAMPTTIKELNERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERVMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENIIKNVM
>LR134305.1|VEE67891.1|756425_756692_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>LR134305.1|VEE67892.1|756694_758413_+|Phosphoenolpyruvate-protein-phosphotransferase-of-PTS-system
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMNGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>LR134305.1|VEE67893.1|758647_758881_-|glutaredoxin
MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDFDEINKVLNIQD
>LR134305.1|VEE67894.1|759078_760440_+|Cytochrome-d-ubiquinol-oxidase-subunit-I
MDTVEISRFLIAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>LR134305.1|VEE67895.1|760436_761456_+|Cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>LR134305.1|VEE67896.1|761588_762251_+|Trk-system-potassium-uptake-protein-trkA
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: LR134305_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_5

1597712-1597794

Orphan

Consensus_repeat	Method
CAACATAGTGAAATTGGATCCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134305_5

>merge|LR134305|5|1597712-1597794|CRISPRCasFinder
CAACATAGTGAAATTGGATCCTCAATTTCTACAGACGATGCAAGTTGGGGAAACGGCCCCAACATAGTGAAATCGGATCCTCA

>LR134305|5|4|1597712-1597794|CRISPRCasFinder
CAACATAGTGAAATTGGATCCTCA	ATTTCTACAGACGATGCAAGTTGGGGAAACGGCCC
CAACATAGTGAAATCGGATCCTCA

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE68646.1\|1599038_1599509_-\|tRNA-(cytosine34-2-O-)-methyltransferase	unknown	unknown	gnl\|CDD\|223297
LR134305.1\|VEE68645.1\|1598280_1598880_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|223440
LR134305.1\|VEE68640.1\|1592837_1593950_-\|Two-component-sensor-protein	unknown	unknown	gnl\|CDD\|226951
LR134305.1\|VEE68653.1\|1614652_1615108_-\|Thiol-peroxidase,-Bcp-type	unknown	unknown	gnl\|CDD\|224146
LR134305.1\|VEE68641.1\|1594112_1594934_+\|ribosomal-large-subunit-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|223638
LR134305.1\|VEE68647.1\|1599513_1600641_-\|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl\|CDD\|272993
LR134305.1\|VEE68650.1\|1603221_1604283_-\|Regulatory-protein	unknown	unknown	gnl\|CDD\|226167
LR134305.1\|VEE68635.1\|1587382_1588579_-\|DNA-repair-exonuclease-family-protein-YhaO	unknown	unknown	gnl\|CDD\|223497
LR134305.1\|VEE68639.1\|1592192_1592816_-\|Two-component-response-regulator-like-protein	unknown	unknown	gnl\|CDD\|225107
LR134305.1\|VEE68638.1\|1591372_1591837_-\|HTH-domain-protein,-binds-to-mecA-promoter-region	unknown	unknown	gnl\|CDD\|224393
LR134305.1\|VEE68634.1\|1584456_1587393_-\|membrane-associated-protein	unknown	unknown	gnl\|CDD\|227061
LR134305.1\|VEE68643.1\|1596965_1597361_-\|membrane-protein	unknown	unknown	unknown
LR134305.1\|VEE68637.1\|1590069_1591194_-\|membrane-protein	unknown	unknown	gnl\|CDD\|226834
LR134305.1\|VEE68648.1\|1600791_1601520_-\|Glutamine-transport-ATP-binding-protein-glnQ	unknown	unknown	gnl\|CDD\|224051
LR134305.1\|VEE68644.1\|1598103_1598256_-\|putative-staphylococcal-protein	unknown	unknown	unknown
LR134305.1\|VEE68642.1\|1595384_1596770_-\|Fumarate-hydratase-class-II	unknown	unknown	gnl\|CDD\|234779
LR134305.1\|VEE68649.1\|1601506_1602964_-\|extracellular-glutamine-binding-protein	unknown	unknown	gnl\|CDD\|223836
LR134305.1\|VEE68651.1\|1613153_1613600_-\|Peroxide-stress-regulator-PerR,-FUR-family	unknown	unknown	gnl\|CDD\|223806
LR134305.1\|VEE68636.1\|1589656_1590001_-\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237467
LR134305.1\|VEE68652.1\|1613696_1614656_-\|D-3-phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240632

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE68646.1\|1599038_1599509_-\|tRNA-(cytosine34-2-O-)-methyltransferase	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
LR134305.1\|VEE68645.1\|1598280_1598880_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
LR134305.1\|VEE68640.1\|1592837_1593950_-\|Two-component-sensor-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.05399e-57
LR134305.1\|VEE68653.1\|1614652_1615108_-\|Thiol-peroxidase,-Bcp-type	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.44283e-68
LR134305.1\|VEE68641.1\|1594112_1594934_+\|ribosomal-large-subunit-pseudouridine-synthase-D	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.26261e-77
LR134305.1\|VEE68647.1\|1599513_1600641_-\|iron-sulfur-cluster-binding-protein	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	7.04522e-180
LR134305.1\|VEE68650.1\|1603221_1604283_-\|Regulatory-protein	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.23611e-122
LR134305.1\|VEE68635.1\|1587382_1588579_-\|DNA-repair-exonuclease-family-protein-YhaO	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	7.33172e-64
LR134305.1\|VEE68639.1\|1592192_1592816_-\|Two-component-response-regulator-like-protein	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.11819e-78
LR134305.1\|VEE68638.1\|1591372_1591837_-\|HTH-domain-protein,-binds-to-mecA-promoter-region	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	5.18868e-15
LR134305.1\|VEE68634.1\|1584456_1587393_-\|membrane-associated-protein	gnl\|CDD\|227061	COG4717, COG4717, Uncharacterized conserved protein [Function unknown].	0
LR134305.1\|VEE68648.1\|1600791_1601520_-\|Glutamine-transport-ATP-binding-protein-glnQ	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.22702e-152
LR134305.1\|VEE68637.1\|1590069_1591194_-\|membrane-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	2.77221e-164
LR134305.1\|VEE68652.1\|1613696_1614656_-\|D-3-phosphoglycerate-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.77676e-134
LR134305.1\|VEE68642.1\|1595384_1596770_-\|Fumarate-hydratase-class-II	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
LR134305.1\|VEE68649.1\|1601506_1602964_-\|extracellular-glutamine-binding-protein	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.48919e-98
LR134305.1\|VEE68651.1\|1613153_1613600_-\|Peroxide-stress-regulator-PerR,-FUR-family	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
LR134305.1\|VEE68636.1\|1589656_1590001_-\|putative-transcriptional-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	1.19759e-37

>LR134305.1|VEE68643.1|1596965_1597361_-|membrane-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>LR134305.1|VEE68642.1|1595384_1596770_-|Fumarate-hydratase-class-II
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>LR134305.1|VEE68641.1|1594112_1594934_+|ribosomal-large-subunit-pseudouridine-synthase-D
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMNKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>LR134305.1|VEE68640.1|1592837_1593950_-|Two-component-sensor-protein
MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGVSNESIAKQAFKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK
>LR134305.1|VEE68639.1|1592192_1592816_-|Two-component-response-regulator-like-protein
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI
>LR134305.1|VEE68638.1|1591372_1591837_-|HTH-domain-protein,-binds-to-mecA-promoter-region
MDRQSFTDLIQTKFKMVRIEAGYTQDTMAQTIGLSKKTLVQIEKERVLPNWTTCISICALFRDSEVLNSTFGCDPLEIVQTISRNHCAYPNHAPTSDIYWNNIETRNGYILQSNKVSNIYRVLNPDNQPIFGTSKMREAETYFNRNAKEELVHI
>LR134305.1|VEE68637.1|1590069_1591194_-|membrane-protein
MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKVTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLDQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQELIRLTSHPKARAIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEQLSIHLSAIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV
>LR134305.1|VEE68636.1|1589656_1590001_-|putative-transcriptional-regulator
MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
>LR134305.1|VEE68635.1|1587382_1588579_-|DNA-repair-exonuclease-family-protein-YhaO
MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDIALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGRHFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQVREEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDESPLVNEFSAELLVDQTVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMRGEQNDN
>LR134305.1|VEE68634.1|1584456_1587393_-|membrane-associated-protein
MIIKSLEIYGYGQFVQRKIEFNKNFTEIFGENEAGKSTIQAFIHSILFGFPTKKSKEPRLEPRLGNQYGGKLVLILDDGLEIEVERIKGSAQGDVKVYLPNGAVRDDAWLQKKLNYISKKTYQGIFSFDVLGLQDIHRNLNEKQLQDYLLQAGALGSTEFTSMREVINRKKDELYKKSGKNPIINQQIEQLKQLESQIREEEAKLETYHRLVDDRDKSSRRLENLKHNLNQLSKMHEEKQKEVALHDHSQEWKSLEQQLNIEPITFPEKGVDRYEKARAHKQSLERDIGLRNERLAQLKEEATQLEPVKQSDIDAFISLNQQENEIKNKEFELTAIEKDIANKQRDKDELQANIGWSETHHDVDSSEAMKSYVSEQIKNKQEQAAYIKQLERSLEENKIEDNAVHSELDSVEEKIVPEETFEKKKEYSQQVIELNEKENLYSKLKERFEIEQQEKQKRQKLLRTTFILLTLVGIGLTAFSFISNNMLFGIIFAVLTLVFVIGIIMSKSKEVDYSEAITDEIEEIKEQLAILDENYDLDFDLDEQYRIRDHWQQALKNKDILEEKRQYIEGRLNDAKGRHDELQSTVENVKDELYLSSKISNDLIVDSISTMANIKALDQHISDLNQQRQQLVQELDTFYNHAEAVTKSQFVYFNKLSLFHDVQQWLKSAEDTNEKWRINAENTKLVTNELNHLNAQLEENNKEITALFDFINVGTEEDFYQHHEDYQTYTSNLSRFNDLTKYLENQNYSYELSSSLSEKTTAQLEEEDHLLATQVDEYNEQYLEMQAQVSDLSAQINHMETDTTLANLRHEYHSLKNQLNDIAKDWASLSYLQSLVDEHIKQIKDKRLPQVINEAVEILKHLTDGRYTMINYNEDSITVKHVNGQLYDPVELSQSTKELLYVALRISLIKVLRPYYPFPLIVDDAFVHFDKKRTEKMLNYLRSLSEHYQVLYFTCVKDNIVPSKEVITLNKIEEGGKR
>LR134305.1|VEE68644.1|1598103_1598256_-|putative-staphylococcal-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>LR134305.1|VEE68645.1|1598280_1598880_-|glucosamine-6-phosphate-deaminase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>LR134305.1|VEE68646.1|1599038_1599509_-|tRNA-(cytosine34-2-O-)-methyltransferase
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>LR134305.1|VEE68647.1|1599513_1600641_-|iron-sulfur-cluster-binding-protein
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDKEDAEVQNEMIKGLDTRRE
>LR134305.1|VEE68648.1|1600791_1601520_-|Glutamine-transport-ATP-binding-protein-glnQ
MPVIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>LR134305.1|VEE68649.1|1601506_1602964_-|extracellular-glutamine-binding-protein
MKCLIRFILILGLLISSAMVYINPTAHAEQDQAWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>LR134305.1|VEE68650.1|1603221_1604283_-|Regulatory-protein
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTELNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>LR134305.1|VEE68651.1|1613153_1613600_-|Peroxide-stress-regulator-PerR,-FUR-family
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>LR134305.1|VEE68652.1|1613696_1614656_-|D-3-phosphoglycerate-dehydrogenase
MTYMRVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLADLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATKTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEPLLIEILKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>LR134305.1|VEE68653.1|1614652_1615108_-|Thiol-peroxidase,-Bcp-type
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG

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Crispr_ID: LR134305_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_6

1898165-1898254

Orphan

Consensus_repeat	Method
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of LR134305_6

>merge|LR134305|6|1898165-1898254|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTACAACTTTAGTTGTTAGGGGCTCTTATGCA

>LR134305|6|5|1898165-1898254|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTT
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE68944.1\|1889478_1889922_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	unknown	unknown	gnl\|CDD\|223854
LR134305.1\|VEE68956.1\|1902544_1903327_-\|ATP-binding-ATP-transporter-protein	unknown	unknown	gnl\|CDD\|224044
LR134305.1\|VEE68950.1\|1895491_1895812_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
LR134305.1\|VEE68945.1\|1890121_1890535_-\|thiol-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|225556
LR134305.1\|VEE68959.1\|1907878_1909684_-\|glucosamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
LR134305.1\|VEE68953.1\|1899450_1900158_-\|SAP-domain-protein	unknown	unknown	unknown
LR134305.1\|VEE68948.1\|1893300_1894239_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
LR134305.1\|VEE68960.1\|1910364_1911903_+\|PTS-system,-mannitol-specific-IIBC-component	unknown	unknown	gnl\|CDD\|225123
LR134305.1\|VEE68957.1\|1903805_1905731_-\|ATP-dependent-DNA-helicase	unknown	unknown	gnl\|CDD\|223288
LR134305.1\|VEE68952.1\|1897059_1898151_+\|Lytic-regulatory-protein	unknown	unknown	unknown
LR134305.1\|VEE68947.1\|1893039_1893270_-\|membrane-protein	unknown	unknown	unknown
LR134305.1\|VEE68951.1\|1895813_1896794_+\|Cobalt-zinc-cadmium-resistance-protein	unknown	unknown	gnl\|CDD\|224151
LR134305.1\|VEE68962.1\|1914081_1914516_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
LR134305.1\|VEE68946.1\|1890992_1892366_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
LR134305.1\|VEE68943.1\|1888647_1889358_+\|Purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
LR134305.1\|VEE68955.1\|1901619_1902477_-\|Putative-cytosolic-protein	unknown	unknown	gnl\|CDD\|223635
LR134305.1\|VEE68954.1\|1900442_1900571_-\|SAP-domain-protein	unknown	unknown	unknown
LR134305.1\|VEE68958.1\|1905723_1907727_-\|recombinational-DNA-repair-ATPase,-RecF_1	unknown	unknown	gnl\|CDD\|226121
LR134305.1\|VEE68961.1\|1911937_1914070_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234
LR134305.1\|VEE68949.1\|1894674_1895340_-\|oxidoreductase-ylbE	unknown	unknown	gnl\|CDD\|187554

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE68944.1\|1889478_1889922_-\|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
LR134305.1\|VEE68956.1\|1902544_1903327_-\|ATP-binding-ATP-transporter-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	3.34818e-98
LR134305.1\|VEE68950.1\|1895491_1895812_+\|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.28971e-17
LR134305.1\|VEE68945.1\|1890121_1890535_-\|thiol-disulfide-oxidoreductase	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	1.9904e-45
LR134305.1\|VEE68959.1\|1907878_1909684_-\|glucosamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
LR134305.1\|VEE68961.1\|1911937_1914070_+\|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.14637e-68
LR134305.1\|VEE68948.1\|1893300_1894239_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
LR134305.1\|VEE68960.1\|1910364_1911903_+\|PTS-system,-mannitol-specific-IIBC-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
LR134305.1\|VEE68957.1\|1903805_1905731_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.52057e-50
LR134305.1\|VEE68951.1\|1895813_1896794_+\|Cobalt-zinc-cadmium-resistance-protein	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.73825e-109
LR134305.1\|VEE68962.1\|1914081_1914516_+\|PTS-system-mannitol-specific-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
LR134305.1\|VEE68946.1\|1890992_1892366_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
LR134305.1\|VEE68943.1\|1888647_1889358_+\|Purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
LR134305.1\|VEE68955.1\|1901619_1902477_-\|Putative-cytosolic-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.04041e-59
LR134305.1\|VEE68958.1\|1905723_1907727_-\|recombinational-DNA-repair-ATPase,-RecF_1	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	1.17368e-29
LR134305.1\|VEE68949.1\|1894674_1895340_-\|oxidoreductase-ylbE	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.60938e-47

>LR134305.1|VEE68952.1|1897059_1898151_+|Lytic-regulatory-protein
MFTYFKSALKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQNIAIYSQFGQKPPGDEYLKVIAVLLIAAIVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGIYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>LR134305.1|VEE68951.1|1895813_1896794_+|Cobalt-zinc-cadmium-resistance-protein
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHQAHHHAHVH
>LR134305.1|VEE68950.1|1895491_1895812_+|Zn(II)-or-Co(II)-specific-transcriptional-repressor-protein
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVSHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>LR134305.1|VEE68949.1|1894674_1895340_-|oxidoreductase-ylbE
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>LR134305.1|VEE68948.1|1893300_1894239_-|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>LR134305.1|VEE68947.1|1893039_1893270_-|membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>LR134305.1|VEE68946.1|1890992_1892366_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>LR134305.1|VEE68945.1|1890121_1890535_-|thiol-disulfide-oxidoreductase
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>LR134305.1|VEE68944.1|1889478_1889922_-|Non-specific-DNA-binding-protein-Dps-/-Iron-binding-ferritin-like-antioxidant-protein-/-Ferroxidase
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>LR134305.1|VEE68943.1|1888647_1889358_+|Purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>LR134305.1|VEE68953.1|1899450_1900158_-|SAP-domain-protein
MVENYIDENCDDKVAEIYKFEFQRKYDNGDFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNVYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASDMYERLIYNKNLSNNIIFELFKKDTQDYSDLEEQLIEKFINYVVSYVKKEGWSNTLLELSKMLENGYTIDKEDEYLSKYIITDIDYLKKLESKINVAIDSRSGEIHLILDDDSLDILIQNQKYGNEF
>LR134305.1|VEE68954.1|1900442_1900571_-|SAP-domain-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDFEIINSIKN
>LR134305.1|VEE68955.1|1901619_1902477_-|Putative-cytosolic-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMICSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>LR134305.1|VEE68956.1|1902544_1903327_-|ATP-binding-ATP-transporter-protein
MLITLNHVGRLKQGKPILQDVSWQIDEGDKWVLYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKLGYSAENVRQQIGFVSHSLLEKFQEGETVIDVVMSGAFKSIGLYKNVDDDIISEAHQLLKLVEMSDKAQQFIGYLSTGEKQRVMIARALMGQPRILILDEPAAGLDFIARESLLNILDSLSDTYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSYFFRKKVAVQRWNNRFSMAMLE
>LR134305.1|VEE68957.1|1903805_1905731_-|ATP-dependent-DNA-helicase
MNNRILEHEWKPSDDVTLEDSALHAIRASSHVAIAAGPGAGKTELLAHKAGYLIETGMCPYPKKILAISFKTDAARNLQERVELRYGKGVEKRFESKTFDAFAKGILDQFIHALPKEYQPQKNYEIILNEKSLNDIINAYITEPYSYYSNWQYEYHINSVLRTMKETKLPIVSFEDDLYSWINERLWMALLNGKGNLKSSLTFSMISILVEYLLKENPLLVKALQATYSHVFLDEFQDTTHIQYNLLKTIFLKSNTVITAVGDNKQRIMGWAGALQNAFGIFKTDFNATQYTLLNNFRSAPNLVYIQNIFSKTLNDASIEVLPAGEWNKNEGVCEIWNFKNHNIEAILLASYISKWMKVENLKPRDFCIIVKQHEHIYAAEIMKELSKINIKSRIEKDYQDLLSEELVLLIIRFLKLSYEEKSPELWLNVIDEIIDMKYSDADSESINYLIIEKELVKMLDEVRKLYSNINDTNFNTQFAEILQEIVVFLGEDIIKATYPKYNQANYFNEVMQKMIDKLQYQNCISMRGLVQEFCGEYSIPIMTIHKSKGLEYHTVFFIGVEDDAFWSFSTQKEADKNAFFVALSRAKQKIIFTISEKRNILKFGEEKNILQETKNISELIQTLMDAGVPLIEKSGLDNIL
>LR134305.1|VEE68958.1|1905723_1907727_-|recombinational-DNA-repair-ATPase,-RecF_1
MLISELHISNFRSFGNESQMIEIADLTALIGANSSGKTSLIMALLRLFGQKNTDRTLIKTDFHIPESADISKINEIDLMIEAKVIFPELKLESPANIKTVPEFIKHLIIEETDADPYLRIRLKGKWIQGSTPEGNIEQELVYVKIPYGREEKEEDLTRVPIHHQKLIQMMYIPAMRDPAKQLKNASGTLLWRIFDGIDWPENLNDYIKSLTSPIETLFKEIPSIKDIQGILNNQWNKYHKDKRYSNSQFKFNGNSLQEFLKNAEILFNPTIDGNSVKVDSLGDGLKSLFYITLVSTLLEIENKQEKDDKPLLNILAIEEPENHISQHLLGRIVRNLKEISKKDNAQVILSSHNSSIIGKVDPEYIRHLQIQNSESIVNNITLPEKNDDAHTYIKEAVKAYPDLYFSKLVILGEGDSEEIVLPKLLSADNIYLDDFNISVVPLGGRYVNHMWKLLNDLSIPHVTLLDLDRERGGGDWGRIKYVLKQLDENNRCSEQLRTVLLIPSNTYHTYSMEEIEDFHNRKSNRLNSLNTWIEKLEKEDVFFSYPLDLDFTMLMSFQEEYQNTMERGPQIPKDSNSTEYDEKLKKSIQATLKNEKAIAKTYSEDEKKLMIWYNSLFLGRGKPSTHIAALKDIDENEIIENAPKELLRLIQRVKEKVGLVGGSNIDE
>LR134305.1|VEE68959.1|1907878_1909684_-|glucosamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>LR134305.1|VEE68960.1|1910364_1911903_+|PTS-system,-mannitol-specific-IIBC-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIVGFKVLAPIMKFIMYILSVAVESLVHAHLLPVVSILVEPAKILFLNNAINHGVFTPLGTDQAAKVGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKTPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>LR134305.1|VEE68961.1|1911937_1914070_+|PTS-system-mannitol-(Cryptic)-specific-transporter-subunit-IIA
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGEDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIASPYLTVNPLLPDSDISYVAQFLNTKSTFSETHDKSSNMIDKDDVHVETKDIHGNTSFENEQTSYLTSVLEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>LR134305.1|VEE68962.1|1914081_1914516_+|PTS-system-mannitol-specific-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA

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Crispr_ID: LR134305_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_7

2019468-2019686

Orphan

Consensus_repeat	Method
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG	CRT

3 spacers

The CRISPR arrays of LR134305_7

>merge|LR134305|7|2019468-2019686|CRT
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTGACTTTTGTCAGCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGTCCCCCAACTTGCACATTATTGTATGCTGACTTGCTGTCAGCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG

>LR134305|7|1|2019468-2019686|CRT
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG	ACTTTTGTCAGCTTCTGT
GTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTT	CTTTTTGAAATTCTCTAT
GTTGGGGCCCCGTCCCCCAACTTGCACATTATTGTATGCTG	ACTTGCTGTCAGCTTCTGT
GTTGGGGCCCCGTTCCCCAACTTGCACATTATTGTAAGCTG

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE69056.1\|2015844_2016096_+\|membrane-protein	unknown	unknown	unknown
LR134305.1\|VEE69052.1\|2010003_2010168_+\|DNA-repair/chromosome-segregation-ATPase	unknown	unknown	unknown
LR134305.1\|VEE69059.1\|2017447_2018659_+\|Major-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|341042
LR134305.1\|VEE69051.1\|2008962_2009871_-\|AEC-family-malonate-efflux-carrier	unknown	unknown	gnl\|CDD\|223751
LR134305.1\|VEE69062.1\|2020910_2021510_-\|molybdopterin-guanine-dinucleotide-biosynthesis-mobA	unknown	unknown	gnl\|CDD\|234725
LR134305.1\|VEE69058.1\|2017014_2017455_+\|MarR-family-regulatory-protein	unknown	unknown	gnl\|CDD\|197670
LR134305.1\|VEE69068.1\|2024515_2025022_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|223595
LR134305.1\|VEE69063.1\|2021516_2021750_-\|Molybdopterin-converting-factor,-subunit-1	unknown	unknown	gnl\|CDD\|340452
LR134305.1\|VEE69067.1\|2024019_2024514_+\|Molybdenum-cofactor-biosynthesis-protein-C	unknown	unknown	gnl\|CDD\|236483
LR134305.1\|VEE69054.1\|2010906_2014074_-\|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein	unknown	unknown	gnl\|CDD\|223911
LR134305.1\|VEE69066.1\|2022697_2023957_-\|Molybdopterin-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|238452
LR134305.1\|VEE69057.1\|2016087_2016852_-\|glyoxalase-like-domain-protein	unknown	unknown	gnl\|CDD\|379203
LR134305.1\|VEE69070.1\|2026225_2026831_-\|Molybdenum-transport-ATP-binding-protein-modC	unknown	unknown	gnl\|CDD\|226628
LR134305.1\|VEE69055.1\|2014190_2015456_-\|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis	unknown	unknown	gnl\|CDD\|225224
LR134305.1\|VEE69065.1\|2022215_2022701_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
LR134305.1\|VEE69069.1\|2025052_2026057_-\|Molybdopterin-biosynthesis-MoeB-protein	unknown	unknown	gnl\|CDD\|181084
LR134305.1\|VEE69064.1\|2021755_2022202_-\|Molybdenum-cofactor-biosynthesis-protein-E	unknown	unknown	gnl\|CDD\|223391
LR134305.1\|VEE69053.1\|2010402_2010720_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE69060.1\|2018760_2019111_-\|Transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
LR134305.1\|VEE69061.1\|2019868_2020891_-\|Molybdenum-cofactor-biosynthesis-protein-A	unknown	unknown	gnl\|CDD\|274250

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE69070.1\|2026225_2026831_-\|Molybdenum-transport-ATP-binding-protein-modC	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	2.92314e-114
LR134305.1\|VEE69059.1\|2017447_2018659_+\|Major-facilitator-family-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17031e-72
LR134305.1\|VEE69051.1\|2008962_2009871_-\|AEC-family-malonate-efflux-carrier	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	3.9513e-43
LR134305.1\|VEE69064.1\|2021755_2022202_-\|Molybdenum-cofactor-biosynthesis-protein-E	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	1.13754e-57
LR134305.1\|VEE69058.1\|2017014_2017455_+\|MarR-family-regulatory-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.824e-15
LR134305.1\|VEE69068.1\|2024515_2025022_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.00506e-64
LR134305.1\|VEE69062.1\|2020910_2021510_-\|molybdopterin-guanine-dinucleotide-biosynthesis-mobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	1.09736e-66
LR134305.1\|VEE69063.1\|2021516_2021750_-\|Molybdopterin-converting-factor,-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	5.99629e-25
LR134305.1\|VEE69067.1\|2024019_2024514_+\|Molybdenum-cofactor-biosynthesis-protein-C	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.70933e-97
LR134305.1\|VEE69054.1\|2010906_2014074_-\|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
LR134305.1\|VEE69066.1\|2022697_2023957_-\|Molybdopterin-biosynthesis-protein-A	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.192e-158
LR134305.1\|VEE69057.1\|2016087_2016852_-\|glyoxalase-like-domain-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	8.12814e-39
LR134305.1\|VEE69055.1\|2014190_2015456_-\|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	8.95714e-143
LR134305.1\|VEE69065.1\|2022215_2022701_-\|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	1.3043e-49
LR134305.1\|VEE69069.1\|2025052_2026057_-\|Molybdopterin-biosynthesis-MoeB-protein	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	5.96924e-132
LR134305.1\|VEE69060.1\|2018760_2019111_-\|Transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
LR134305.1\|VEE69061.1\|2019868_2020891_-\|Molybdenum-cofactor-biosynthesis-protein-A	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165

>LR134305.1|VEE69060.1|2018760_2019111_-|Transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>LR134305.1|VEE69059.1|2017447_2018659_+|Major-facilitator-family-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>LR134305.1|VEE69058.1|2017014_2017455_+|MarR-family-regulatory-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVFLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>LR134305.1|VEE69057.1|2016087_2016852_-|glyoxalase-like-domain-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNQSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>LR134305.1|VEE69056.1|2015844_2016096_+|membrane-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>LR134305.1|VEE69055.1|2014190_2015456_-|FmhB-protein-of-FemAB-family-involved-in-peptidoglycan-interpeptide-biosynthesis
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>LR134305.1|VEE69054.1|2010906_2014074_-|RND-multidrug-efflux-transporter;-Acriflavin-resistance-protein
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGKIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>LR134305.1|VEE69053.1|2010402_2010720_+|Uncharacterised-protein
MQFYLILLAILYLIVSFISIFKMEVIFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>LR134305.1|VEE69052.1|2010003_2010168_+|DNA-repair/chromosome-segregation-ATPase
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>LR134305.1|VEE69051.1|2008962_2009871_-|AEC-family-malonate-efflux-carrier
MTEQFTMIILLIALGYFLKRINYIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>LR134305.1|VEE69061.1|2019868_2020891_-|Molybdenum-cofactor-biosynthesis-protein-A
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>LR134305.1|VEE69062.1|2020910_2021510_-|molybdopterin-guanine-dinucleotide-biosynthesis-mobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYRRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>LR134305.1|VEE69063.1|2021516_2021750_-|Molybdopterin-converting-factor,-subunit-1
MKVLYFAEIKDILQKAQEDIMLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>LR134305.1|VEE69064.1|2021755_2022202_-|Molybdenum-cofactor-biosynthesis-protein-E
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGIKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>LR134305.1|VEE69065.1|2022215_2022701_-|Molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVGVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>LR134305.1|VEE69066.1|2022697_2023957_-|Molybdopterin-biosynthesis-protein-A
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>LR134305.1|VEE69067.1|2024019_2024514_+|Molybdenum-cofactor-biosynthesis-protein-C
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>LR134305.1|VEE69068.1|2024515_2025022_-|molybdenum-cofactor-biosynthesis-protein-B
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>LR134305.1|VEE69069.1|2025052_2026057_-|Molybdopterin-biosynthesis-MoeB-protein
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQLIDTKITYGDIWEGSHYSFGFSKMQRSACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>LR134305.1|VEE69070.1|2026225_2026831_-|Molybdenum-transport-ATP-binding-protein-modC
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKTDEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: LR134305_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_8

2237029-2237124

Orphan

Consensus_repeat	Method
CAACTGTATTCCTCTATACCTGTAATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134305_8

>merge|LR134305|8|2237029-2237124|CRISPRCasFinder
CAACTGTATTCCTCTATACCTGTAATTTTAATTACTAGAGGCTCTTATACAGTTGTTGCGAAGCAAGCAACTGTATTCCTCTATACCTGTAATTTT

>LR134305|8|6|2237029-2237124|CRISPRCasFinder
CAACTGTATTCCTCTATACCTGTAATTTT	AATTACTAGAGGCTCTTATACAGTTGTTGCGAAGCAAG
CAACTGTATTCCTCTATACCTGTAATTTT

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE69268.1\|2237887_2238250_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE69276.1\|2244844_2245138_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE69260.1\|2228893_2229643_-\|nickel-transport-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
LR134305.1\|VEE69277.1\|2245140_2245467_-\|Putative-cytosolic-protein	unknown	unknown	unknown
LR134305.1\|VEE69266.1\|2235296_2236115_-\|nicotianamine-synthase	unknown	unknown	gnl\|CDD\|176222
LR134305.1\|VEE69270.1\|2239566_2241105_+\|aminobenzoyl-glutamate-transport-protein	unknown	unknown	gnl\|CDD\|367668
LR134305.1\|VEE69271.1\|2241216_2241639_-\|transposase	unknown	unknown	gnl\|CDD\|225039
LR134305.1\|VEE69272.1\|2242093_2242513_-\|membrane-protein	unknown	unknown	gnl\|CDD\|284628
LR134305.1\|VEE69262.1\|2230447_2231317_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	unknown	unknown	gnl\|CDD\|224094
LR134305.1\|VEE69275.1\|2244299_2244491_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE69259.1\|2227688_2228882_-\|Antibiotic-resistance-protein	unknown	unknown	gnl\|CDD\|341042
LR134305.1\|VEE69267.1\|2236125_2236947_-\|Putative-Similar-to-diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|223331
LR134305.1\|VEE69264.1\|2232261_2233860_-\|Oligopeptide-transporter-putative-substrate-binding-domain-protein	unknown	unknown	gnl\|CDD\|274072
LR134305.1\|VEE69269.1\|2238513_2239332_-\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|181491
LR134305.1\|VEE69273.1\|2242763_2243459_-\|Short-chain-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|226674
LR134305.1\|VEE69265.1\|2234002_2235304_-\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|226839
LR134305.1\|VEE69261.1\|2229635_2230451_-\|Oligopeptide-transporter-putative-ATPase-domain-protein	unknown	unknown	gnl\|CDD\|223521
LR134305.1\|VEE69263.1\|2231313_2232249_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	unknown	unknown	gnl\|CDD\|223674
LR134305.1\|VEE69258.1\|2226715_2227465_+\|membrane-protein	unknown	unknown	unknown
LR134305.1\|VEE69274.1\|2243758_2244040_+\|IraB-protein	unknown	unknown	gnl\|CDD\|377790

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE69260.1\|2228893_2229643_-\|nickel-transport-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.955e-107
LR134305.1\|VEE69266.1\|2235296_2236115_-\|nicotianamine-synthase	gnl\|CDD\|176222	cd08261, Zn_ADH7, Alcohol dehydrogenases of the MDR family. This group contains members identified as related to zinc-dependent alcohol dehydrogenase and other members of the MDR family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group includes various activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0.000101006
LR134305.1\|VEE69270.1\|2239566_2241105_+\|aminobenzoyl-glutamate-transport-protein	gnl\|CDD\|367668	pfam03806, ABG_transport, AbgT putative transporter family.	0
LR134305.1\|VEE69271.1\|2241216_2241639_-\|transposase	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.64055e-29
LR134305.1\|VEE69272.1\|2242093_2242513_-\|membrane-protein	gnl\|CDD\|284628	pfam07252, DUF1433, Protein of unknown function (DUF1433). This family contains a number of hypothetical bacterial proteins of unknown function approximately 100 residues in length.	3.33575e-38
LR134305.1\|VEE69262.1\|2230447_2231317_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.12719e-84
LR134305.1\|VEE69259.1\|2227688_2228882_-\|Antibiotic-resistance-protein	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.31594e-79
LR134305.1\|VEE69267.1\|2236125_2236947_-\|Putative-Similar-to-diaminopimelate-epimerase	gnl\|CDD\|223331	COG0253, DapF, Diaminopimelate epimerase [Amino acid transport and metabolism].	1.49398e-71
LR134305.1\|VEE69264.1\|2232261_2233860_-\|Oligopeptide-transporter-putative-substrate-binding-domain-protein	gnl\|CDD\|274072	TIGR02294, Nickel-binding_periplasmic_protein, nickel ABC transporter, nickel/metallophore periplasmic binding protein. Members of this family are periplasmic nickel-binding proteins of nickel ABC transporters. Most appear to be lipoproteins. This protein was previously (circa 2003) thought to mediate binding to nickel through water molecules, but is now thought to involve a chelating organic molecule, perhaps butane-1,2,4-tricarboxylate, acting as a metallophore. [Transport and binding proteins, Cations and iron carrying compounds].	0
LR134305.1\|VEE69269.1\|2238513_2239332_-\|short-chain-dehydrogenase	gnl\|CDD\|181491	PRK08589, PRK08589, SDR family oxidoreductase.	0
LR134305.1\|VEE69273.1\|2242763_2243459_-\|Short-chain-alcohol-dehydrogenase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	9.67028e-99
LR134305.1\|VEE69265.1\|2234002_2235304_-\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|226839	COG4408, COG4408, Uncharacterized protein conserved in bacteria [Function unknown].	0
LR134305.1\|VEE69261.1\|2229635_2230451_-\|Oligopeptide-transporter-putative-ATPase-domain-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.55691e-118
LR134305.1\|VEE69263.1\|2231313_2232249_-\|Oligopeptide-transporter-putative-membrane-permease-domain-protein	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.46808e-99
LR134305.1\|VEE69274.1\|2243758_2244040_+\|IraB-protein	gnl\|CDD\|377790	pfam07205, DUF1413, Domain of unknown function (DUF1413). This family consists of several hypothetical bacterial proteins which seem to be specific to firmicute species. Members of this family are typically around 100 residues in length. The function of this family is unknown.	6.5904e-16

>LR134305.1|VEE69267.1|2236125_2236947_-|Putative-Similar-to-diaminopimelate-epimerase
MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVCCEQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCSDLVQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVNQVTIEIQHLVETYVREQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASIGVFNNYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE
>LR134305.1|VEE69266.1|2235296_2236115_-|nicotianamine-synthase
MNNFNNEIKLILQQYLEKFEAHYERVLQDNQYIEALETLMDDYSEFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDNIEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV
>LR134305.1|VEE69265.1|2234002_2235304_-|Uncharacterized-protein-conserved-in-bacteria
MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLYQAYKKEKQFEVKIQNEAHQHLEGKFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQQLSLETLQSVKHVILISPTFGSQMIVEQFMSKFSQDIEVISFSTYLGDTRIVDKEAPNHVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPPLFMNDFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQVFRVPSVNLLQFMVKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYSAILIDPFSQPDENGHYFDFSAVPFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIQTPMIDQFLARYEASCQAYKDMHQDQHLSSQFNTNLFEEDKALVTKFLEINRTLS
>LR134305.1|VEE69264.1|2232261_2233860_-|Oligopeptide-transporter-putative-substrate-binding-domain-protein
MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIGDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWEVSEDGKTYTFHLRDDVKFHDGTPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQVDDEGIFIPISHGSMTVVAPKDLEKVSFTQSQYELPFNEMQYK
>LR134305.1|VEE69263.1|2231313_2232249_-|Oligopeptide-transporter-putative-membrane-permease-domain-protein
MFKFILKRIALMFPLMIVVSFMTFLLTYITNENPAVTILHAQGTPNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNTLKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVSVKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVKSITLMLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPVIQAYVLIVAVLFIVFNTLADIINALLNPRLREGAR
>LR134305.1|VEE69262.1|2230447_2231317_-|Oligopeptide-transporter-putative-membrane-permease-domain-protein
MIILKRLLQDKGAVIALGIIVLYVFLGLAAPLVTFYDPNHIDTANKFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQGFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVMQYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLGVKAPTAEWGMMLNEARKVMFTHPEMVFAPGIAIVIIVMAFNFLSDALQIAIDPRISSKDKLRSVKKGVVQS
>LR134305.1|VEE69261.1|2229635_2230451_-|Oligopeptide-transporter-putative-ATPase-domain-protein
MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGKSITCKSIVGLNPERLRVTGDITFDGKPMLSLSEAQLKKYRGKDIAMVMQQGSRAFDPSTTVGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLMIALALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIADRVVVMKNGQLIEHGTRESVLHHPEHVYTKYLLSTKKKINDHFKHVMRGDVHD
>LR134305.1|VEE69260.1|2228893_2229643_-|nickel-transport-ATP-binding-protein
MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESGSGKSTLSRMILGIEKPDKGCVTLNDQPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREILFEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKIEEQIPTSALHKSDNAYTRELIEKQLSF
>LR134305.1|VEE69259.1|2227688_2228882_-|Antibiotic-resistance-protein
MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVIGIVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARVMQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNISLFAIVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAITVFAQFFKNKELLNSGIIMIVASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHPKYMVSVLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVGRNMLLGLFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPRPANSL
>LR134305.1|VEE69258.1|2226715_2227465_+|membrane-protein
MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVFLTFGLVAVFTQQAPWGFSFPISMNISYLLAVIISLAIFRRMHEDAFVPMIRSQIVASAKYKWHILISFTLSIVLFLLLNHFYIFALNVDSFTVFDIYPLIREYGSISLIAIFSLTIILNTLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILASSATYLYLKSNRNFMVSYFYQLAVILVLHIFM
>LR134305.1|VEE69268.1|2237887_2238250_-|Uncharacterised-protein
MLKEKESFRLLYQAIREIADKIGDNQLETNSVSLLLLDFDFEHEVFDELHLAILKYLNTVSIENISHSELLNLIGNTIPEDREINTFVKNKIIIGFANNYFPELQVLANEIKSDMASSLK
>LR134305.1|VEE69269.1|2238513_2239332_-|short-chain-dehydrogenase
MKRLENKVAVVTGASTGIGQASAIALAQEGAYVLAVDIAEVVSETVDKIKSNGDKAKAYIVDIASEQQIDNFASEIREQFGHVDVLFNNAGVDNAAGRIHEYPTDVYDKIMNVDMRGTFLMTKMMLPLMMTKGGSIVNTASFSGQAADLYRSGYNAAKGAVINFTKSIAIEYGRDGIRANAIAPGTIETPLVDKLTGTCEDKEGKAFRENQKWMTPLGRLGKPEEVGKLVVFLASDESSFITGETIRIDGGVMAYTWPGEMLSDDSWKRTLE
>LR134305.1|VEE69270.1|2239566_2241105_+|aminobenzoyl-glutamate-transport-protein
MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCVGLAIMTWVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIGVAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIGYHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIAASVVVLLPTILLVTTKLIIPRLGQYDDRLMHDDHEETSSHITDKEAHALKWANISFIVTIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKNTKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLILGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITPMMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGPIFVK
>LR134305.1|VEE69271.1|2241216_2241639_-|transposase
MPYNYKKQNGELMSVMSQGEKFIHQSPVNDELSALIKLLISKINGCHYCVDIHKKELKELGVTQMKIDEVLSFRHLDLFTDQEKVTLEFAEMLNSIKDFKKFEIIDRLKSFYDEEQIIDLVFVVNQINGWNRLNIISDKL
>LR134305.1|VEE69272.1|2242093_2242513_-|membrane-protein
MTKKHVFIIIGVILCICIVATVIYLKVKYDEKEKQKALYYKEQQERITLYLKHNTKEPNTIKTVHFTSLKTGPMGDAVIEGYINENKKADFVAYGSPEHNYQFGGDMIESEKLSELLKPANQLKSPDEIKEELDKKEGH
>LR134305.1|VEE69273.1|2242763_2243459_-|Short-chain-alcohol-dehydrogenase
MTVLTDKVAVVTGAGSGIGEAIATLLHEEGVKVILAGRNKDKLQNVANQLAQDSVKVVPTDVTKKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSISPGMVDTAITAAYNPTDRKKLEPQDIAEAVLYALTQPKHVNVNEITVRPV
>LR134305.1|VEE69274.1|2243758_2244040_+|IraB-protein
MTYHERVLALRAERKRTAFDFRFEDLFSKEEWLSMSLAERQKAEKAFRHEVKKLDDVRMPFSSAHDAQVKLYNVVYSYNGIKRNFKQVENEGF
>LR134305.1|VEE69275.1|2244299_2244491_-|Uncharacterised-protein
MRKEIEALIFSDVSSYDIYVNTGVNQGLIGDIKDGYLTIDSMPYIDAERLYHFAMERKSLVTN
>LR134305.1|VEE69276.1|2244844_2245138_-|Uncharacterised-protein
MWYDSVVERIPSVPSINAVLQMRQITAVIAPEHNRIHHDHKNKLKNDEELLINQMSSHFKKFKGEFDNVAQGDWVKKAKNELDDISKKLKNIQRTEV
>LR134305.1|VEE69277.1|2245140_2245467_-|Putative-cytosolic-protein
MFTEYKKISDLETAYDEERRKLNDKLEQLQEIKHQIKLDCEYSYDCFLYLKNKMDYSQESNVKMTHIINEFNDEMTQRIKNEEMKIERSKDELKSEYLKEIEKMGGRE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: LR134305_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_9

2464228-2464306

Orphan

Consensus_repeat	Method
TTCTCTATGTTGGGGCCCCGCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134305_9

>merge|LR134305|9|2464228-2464306|CRISPRCasFinder
TTCTCTATGTTGGGGCCCCGCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTTTGTTGGGGCCCCGCCAA

>LR134305|9|7|2464228-2464306|CRISPRCasFinder
TTCTCTATGTTGGGGCCCCGCCAA	CTCGCATTGCCTGTAGAATTTCTTTTCGAAA
TTCTCTTTGTTGGGGCCCCGCCAA

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE69469.1\|2469350_2470055_-\|Phosphoribosylformimino-5-aminoimidazole-carboxamide-ribotide-isomerase	unknown	unknown	gnl\|CDD\|172156
LR134305.1\|VEE69470.1\|2470047_2470626_-\|Imidazole-glycerol-phosphate-synthase-amidotransferase-subunit	unknown	unknown	gnl\|CDD\|171871
LR134305.1\|VEE69467.1\|2467966_2468599_-\|Phosphoribosyl-AMP-cyclohydrolase-/-Phosphoribosyl-ATP-pyrophosphatase	unknown	unknown	gnl\|CDD\|235067
LR134305.1\|VEE69464.1\|2462960_2464013_+\|intercellular-adhesion-protein-icaC	unknown	unknown	gnl\|CDD\|226446
LR134305.1\|VEE69473.1\|2472198_2473449_-\|Histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|172308
LR134305.1\|VEE69472.1\|2471169_2472183_-\|Histidinol-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|223157
LR134305.1\|VEE69455.1\|2455676_2456153_-\|Peptide-methionine-sulfoxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|235497
LR134305.1\|VEE69466.1\|2467166_2467430_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE69463.1\|2462101_2462974_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|188448
LR134305.1\|VEE69462.1\|2461799_2462105_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-protein-IcaD	unknown	unknown	gnl\|CDD\|188447
LR134305.1\|VEE69471.1\|2470622_2471201_-\|imidazoleglycerol-phosphate-dehydratase	unknown	unknown	gnl\|CDD\|153419
LR134305.1\|VEE69460.1\|2459873_2460434_-\|Biofilm-operon-icaABCD-HTH-type-negative-transcriptional-regulator-IcaR	unknown	unknown	gnl\|CDD\|376089
LR134305.1\|VEE69458.1\|2457654_2458347_-\|Tyrosine-protein-kinase-EpsD	unknown	unknown	gnl\|CDD\|349772
LR134305.1\|VEE69457.1\|2456890_2457658_-\|Manganese-dependent-protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|226870
LR134305.1\|VEE69465.1\|2464403_2466449_-\|Lipase	unknown	unknown	gnl\|CDD\|224001
LR134305.1\|VEE69456.1\|2456155_2456656_-\|acetyltransferase-(GNAT)-family-protein	unknown	unknown	gnl\|CDD\|379326
LR134305.1\|VEE69459.1\|2458363_2459026_-\|chain-length-regulator-(capsular-polysaccharide-biosynthesis)	unknown	unknown	gnl\|CDD\|226453
LR134305.1\|VEE69468.1\|2468595_2469354_-\|Imidazole-glycerol-phosphate-synthase,-cyclase-subunit	unknown	unknown	gnl\|CDD\|234996
LR134305.1\|VEE69474.1\|2473441_2474056_-\|ATP-phosphoribosyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|172153
LR134305.1\|VEE69461.1\|2460597_2461836_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-N-glycosyltransferase-IcaA	unknown	unknown	gnl\|CDD\|274866

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE69469.1\|2469350_2470055_-\|Phosphoribosylformimino-5-aminoimidazole-carboxamide-ribotide-isomerase	gnl\|CDD\|172156	PRK13587, PRK13587, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Provisional.	2.03626e-167
LR134305.1\|VEE69470.1\|2470047_2470626_-\|Imidazole-glycerol-phosphate-synthase-amidotransferase-subunit	gnl\|CDD\|171871	PRK13142, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	2.74199e-130
LR134305.1\|VEE69467.1\|2467966_2468599_-\|Phosphoribosyl-AMP-cyclohydrolase-/-Phosphoribosyl-ATP-pyrophosphatase	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	3.01463e-110
LR134305.1\|VEE69464.1\|2462960_2464013_+\|intercellular-adhesion-protein-icaC	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	1.16088e-114
LR134305.1\|VEE69473.1\|2472198_2473449_-\|Histidinol-dehydrogenase	gnl\|CDD\|172308	PRK13770, PRK13770, histidinol dehydrogenase; Provisional.	0
LR134305.1\|VEE69472.1\|2471169_2472183_-\|Histidinol-phosphate-aminotransferase	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	4.19528e-82
LR134305.1\|VEE69455.1\|2455676_2456153_-\|Peptide-methionine-sulfoxide-reductase-MsrA	gnl\|CDD\|235497	PRK05528, PRK05528, peptide-methionine (S)-S-oxide reductase.	1.09071e-103
LR134305.1\|VEE69463.1\|2462101_2462974_+\|polysaccharide-deacetylase	gnl\|CDD\|188448	TIGR03933, Poly-beta-16-N-acetyl-D-glucosamine_N-deacetylase, intercellular adhesin biosynthesis polysaccharide N-deacetylase. A common motif in bacterial biosynthesis of polysaccharide for export is modification that follows polymerization. This model describes a subfamily of polysaccharide N-deacetylases that acts on poly-beta-1,6-N-acetyl-D-glyscosamine as produced by Staphylococcus epidermidis and S. aureus. The end product in these species is designated polysaccharide intercellular adhesin (PIA), and this gene designated icaB (intercellular adhesion protein B). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Cellular processes, Pathogenesis].	5.71542e-151
LR134305.1\|VEE69462.1\|2461799_2462105_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-protein-IcaD	gnl\|CDD\|188447	TIGR03932, IcaD_partial, intracellular adhesion protein D. Members of this protein family are IcaD (intracellular adhesion protein D), which with catalytic subunit IcaA forms an N-acetylglucosaminyltransferase. In the absence of IcaC, this enzyme forms N-acetylglucosamine oligomers up to 20 in length. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.14464e-30
LR134305.1\|VEE69471.1\|2470622_2471201_-\|imidazoleglycerol-phosphate-dehydratase	gnl\|CDD\|153419	cd07914, IGPD, Imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase (IGPD; EC 4.2.1.19) catalyzes the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, the sixth step of histidine biosynthesis in plants and microorganisms where the histidine is synthesized de novo. There is an internal repeat in the protein domain that is related by pseudo-dyad symmetry, perhaps as a result of an ancient gene duplication. The apo-form of IGPD exists as a catalytically inactive trimer which, in the presence of specific divalent metal cations such as manganese (Mn2+), cobalt (Co2+), cadmium (Cd2+), nickel (Ni2+), iron (Fe2+) and zinc (Zn2+), assembles to form a biologically active high molecular weight metalloenzyme; a 24-mer with 4-3-2 symmetry. Each 24-mer has 24 active sites, and contains around 1.5 metal ions per monomer, each monomer contributing residues to three separate active sites. IGPD enzymes are monofunctional in fungi, plants, archaea and some eubacteria while they are encoded as bifunctional enzymes in other eubacteria, such that the enzyme is fused to histidinol-phosphate phosphatase, the penultimate enzyme of the histidine biosynthesis pathway. The histidine biosynthesis pathway is a potential target for development of herbicides, and IGPD is a target for the triazole phosphonate herbicides.	7.13364e-103
LR134305.1\|VEE69460.1\|2459873_2460434_-\|Biofilm-operon-icaABCD-HTH-type-negative-transcriptional-regulator-IcaR	gnl\|CDD\|376089	pfam18665, TetR_C_37, Tetracyclin repressor-like, C-terminal domain. IcaR belongs to the tetracycline repressor (TetR) family of proteins, which are involved in a wide variety of gene regulations. It binds to a 42 bp region immediately upstream of the icaA gene. This entry represents the C-terminal domain which is involved in dimerization.	2.88245e-28
LR134305.1\|VEE69458.1\|2457654_2458347_-\|Tyrosine-protein-kinase-EpsD	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.83977e-84
LR134305.1\|VEE69457.1\|2456890_2457658_-\|Manganese-dependent-protein-tyrosine-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.88344e-144
LR134305.1\|VEE69465.1\|2464403_2466449_-\|Lipase	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	4.33785e-81
LR134305.1\|VEE69456.1\|2456155_2456656_-\|acetyltransferase-(GNAT)-family-protein	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.58707e-14
LR134305.1\|VEE69459.1\|2458363_2459026_-\|chain-length-regulator-(capsular-polysaccharide-biosynthesis)	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.17617e-89
LR134305.1\|VEE69468.1\|2468595_2469354_-\|Imidazole-glycerol-phosphate-synthase,-cyclase-subunit	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	1.94565e-155
LR134305.1\|VEE69474.1\|2473441_2474056_-\|ATP-phosphoribosyltransferase-catalytic-subunit	gnl\|CDD\|172153	PRK13584, hisG, ATP phosphoribosyltransferase.	1.23748e-132
LR134305.1\|VEE69461.1\|2460597_2461836_+\|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-N-glycosyltransferase-IcaA	gnl\|CDD\|274866	TIGR03937, Poly-beta-16-N-acetyl-D-glucosamine_synthase, poly-beta-1,6 N-acetyl-D-glucosamine synthase. Members of this protein family are biofilm-forming enzymes that polymerize N-acetyl-D-glucosamine residues in beta(1,6) linkage. One named members is IcaA (intercellular adhesin protein A), an enzyme that acts (with aid of subunit IcaD) in Polysaccharide Intercellular Adhesin (PIA) biosynthesis in Staphylococcus epidermis). The homologous member in E. coli is designated PgaC. Members are often encoded next to a polysaccharide deacetylase and involved in biofilm formation. Note that chitin, although also made from N-acetylglucosamine, is formed with beta-1,4 linkages.	0

>LR134305.1|VEE69464.1|2462960_2464013_+|intercellular-adhesion-protein-icaC
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
>LR134305.1|VEE69463.1|2462101_2462974_+|polysaccharide-deacetylase
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATVIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
>LR134305.1|VEE69462.1|2461799_2462105_+|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-protein-IcaD
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
>LR134305.1|VEE69461.1|2460597_2461836_+|Polysaccharide-intercellular-adhesin-(PIA)-biosynthesis-N-glycosyltransferase-IcaA
MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
>LR134305.1|VEE69460.1|2459873_2460434_-|Biofilm-operon-icaABCD-HTH-type-negative-transcriptional-regulator-IcaR
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
>LR134305.1|VEE69459.1|2458363_2459026_-|chain-length-regulator-(capsular-polysaccharide-biosynthesis)
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
>LR134305.1|VEE69458.1|2457654_2458347_-|Tyrosine-protein-kinase-EpsD
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
>LR134305.1|VEE69457.1|2456890_2457658_-|Manganese-dependent-protein-tyrosine-phosphatase
MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILQGLDNGSIQGINRSKYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYSNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF
>LR134305.1|VEE69456.1|2456155_2456656_-|acetyltransferase-(GNAT)-family-protein
MVLRKVIMQDLDQIIALENIGFSPEEAATPEALKLRIEQIQETFIVAEKNDEVIGYINGPVIKERYISDDLFKNVPTNNSEGGYISVLGLVVAPNYQGQGIAGRLLNYFENLAKNQHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNIKKDDEV
>LR134305.1|VEE69455.1|2455676_2456153_-|Peptide-methionine-sulfoxide-reductase-MsrA
MAVVYVAGGCLWGVEAFFTTIPGIIHTEVGRANGRSSKLDSPYDGYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNRQGNDIGEKYRTGLYSCVDDYLIEARQFIERRKDRDKIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISIDLLNKYK
>LR134305.1|VEE69465.1|2464403_2466449_-|Lipase
MMKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKKSSLNNKNIQRDTTKNSNANPSDVNQGLEQAINDGKQSKVASQQQSKEADNSQDSNANNNLPSQSRTKEALPLNKSNQTSQPEIVNKTEIEKVQPQQNNQANDKITNYNFNNEKEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKGDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNNDNMISSITTLGTPHNGTHASDLAGNEALVKQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTNATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVHTREELQDFWHHLADDLVKTEKVTDTKQA
>LR134305.1|VEE69466.1|2467166_2467430_-|Uncharacterised-protein
MKKLFNEYFFTTSQATALIIFSLPMTDLFTKNFLLYMLLFIVIIGSTFFIERELSKKYSLQEKAKKLCLSLLPINIIVVFIFFVFIL
>LR134305.1|VEE69467.1|2467966_2468599_-|Phosphoribosyl-AMP-cyclohydrolase-/-Phosphoribosyl-ATP-pyrophosphatase
MTNYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGLVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
>LR134305.1|VEE69468.1|2468595_2469354_-|Imidazole-glycerol-phosphate-synthase,-cyclase-subunit
MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
>LR134305.1|VEE69469.1|2469350_2470055_-|Phosphoribosylformimino-5-aminoimidazole-carboxamide-ribotide-isomerase
MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDADWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVKQLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
>LR134305.1|VEE69470.1|2470047_2470626_-|Imidazole-glycerol-phosphate-synthase-amidotransferase-subunit
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNKQNIIDQAETIILPGVGHFKDAMSEIKRLNLDAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGTDIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND
>LR134305.1|VEE69471.1|2470622_2471201_-|imidazoleglycerol-phosphate-dehydratase
MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNATLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
>LR134305.1|VEE69472.1|2471169_2472183_-|Histidinol-phosphate-aminotransferase
MIYIDKNESPITPLDEKTMTSIISATPYNLYPDAAYEQFKDAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDIAFLTAIADKMKAINGYFVIDEAYLDYGMAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIQRIQKIEHPYPLNVFTLNIATYIFRHRQETSRFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEQVMKGYVRYSIATASQLKQLEEIVKEWSTKYDLSKTTKHS
>LR134305.1|VEE69473.1|2472198_2473449_-|Histidinol-dehydrogenase
MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYNLTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEKSVECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSKEVLAACYITQVNQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGIDQIAGPTEIALIIDDTADLDAIVYDVFAQAEHDELARTYVISEDAQVLKDLESRIAKALPNVDRYDIVSKSIANQHYLIHASNFDEACYVMNTIAPEHASIQTVNPQPYIEKVKYVGALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFDQIADSAQHIAHVEALYNHQQSILIRQS
>LR134305.1|VEE69474.1|2473441_2474056_-|ATP-phosphoribosyltransferase-catalytic-subunit
MLRIAIAKGRLMDSLINYLDAIEFTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGIADIGIVGSDILDERHYNVNNLLDMPFGACHFAVAAKPETTNYRKIATSYVHTAEAYFKSKGIDVELIKLSGSVELACVVDMVDGIVDIVQTGTTLEANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA

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Crispr_ID: LR134305_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134305_10

2493547-2493632

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134305_10

>merge|LR134305|10|2493547-2493632|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>LR134305|10|8|2493547-2493632|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
LR134305.1\|VEE69486.1\|2486136_2486949_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225073
LR134305.1\|VEE69501.1\|2502040_2503174_+\|DNA-polymerase-III-beta-subunit	unknown	unknown	gnl\|CDD\|235541
LR134305.1\|VEE69488.1\|2488046_2488805_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
LR134305.1\|VEE69502.1\|2503563_2503800_+\|S4-domain-containing-protein-YaaA	unknown	unknown	gnl\|CDD\|274378
LR134305.1\|VEE69500.1\|2500399_2501761_+\|Chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl\|CDD\|273037
LR134305.1\|VEE69491.1\|2491677_2492247_-\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|238045
LR134305.1\|VEE69485.1\|2484877_2485894_+\|nickel-transport-protein	unknown	unknown	gnl\|CDD\|225911
LR134305.1\|VEE69494.1\|2493990_2494830_-\|Chromosome-(plasmid)-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|275105
LR134305.1\|VEE69489.1\|2488794_2490675_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
LR134305.1\|VEE69492.1\|2492506_2492902_-\|membrane-protein	unknown	unknown	gnl\|CDD\|288237
LR134305.1\|VEE69490.1\|2490766_2490958_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134305.1\|VEE69496.1\|2495591_2497469_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	unknown	unknown	gnl\|CDD\|235362
LR134305.1\|VEE69495.1\|2494872_2495592_-\|Ribosomal-RNA-small-subunit-methyltransferase-G	unknown	unknown	gnl\|CDD\|234637
LR134305.1\|VEE69497.1\|2497535_2498915_-\|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase	unknown	unknown	gnl\|CDD\|235392
LR134305.1\|VEE69498.1\|2499057_2499405_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
LR134305.1\|VEE69499.1\|2499531_2499669_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
LR134305.1\|VEE69503.1\|2503796_2504909_+\|DNA-recombination-and-repair-protein-RecF	unknown	unknown	gnl\|CDD\|273173
LR134305.1\|VEE69487.1\|2487244_2487757_-\|membrane-spanning-protein	unknown	unknown	gnl\|CDD\|225786
LR134305.1\|VEE69484.1\|2484138_2484714_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|181104
LR134305.1\|VEE69493.1\|2492969_2493323_-\|Permease	unknown	unknown	gnl\|CDD\|288237

Protein	Function_ID	Function_description	E-value
LR134305.1\|VEE69486.1\|2486136_2486949_+\|N-acetyltransferase	gnl\|CDD\|225073	COG2162, NhoA, Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism].	2.45311e-103
LR134305.1\|VEE69501.1\|2502040_2503174_+\|DNA-polymerase-III-beta-subunit	gnl\|CDD\|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	3.87922e-156
LR134305.1\|VEE69488.1\|2488046_2488805_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.13228e-111
LR134305.1\|VEE69502.1\|2503563_2503800_+\|S4-domain-containing-protein-YaaA	gnl\|CDD\|274378	TIGR02988, YaaA_near_RecF, S4 domain protein YaaA. This small protein has a single S4 domain (pfam01479), as do bacterial ribosomal protein S4, some pseudouridine synthases, tyrosyl-tRNA synthetases. The S4 domain may bind RNA. Members of this protein family are found almost exclusively in the Firmicutes, and almost invariably just a few nucleotides upstream of the gene for the DNA replication and repair protein RecF. The few members of this family that are not near recF are found instead near dnaA and/or dnaN, the usual neighbors of recF, near the origin of replication. The conserved location suggests a possible role in replication in the Firmicutes lineage. [DNA metabolism, DNA replication, recombination, and repair].	4.30013e-25
LR134305.1\|VEE69500.1\|2500399_2501761_+\|Chromosomal-replication-initiator-protein-DnaA	gnl\|CDD\|273037	TIGR00362, DnaA, chromosomal replication initiator protein DnaA. DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair].	0
LR134305.1\|VEE69491.1\|2491677_2492247_-\|helix-turn-helix-family-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.19983e-16
LR134305.1\|VEE69485.1\|2484877_2485894_+\|nickel-transport-protein	gnl\|CDD\|225911	COG3376, HoxN, High-affinity nickel permease [Inorganic ion transport and metabolism].	6.0873e-170
LR134305.1\|VEE69494.1\|2493990_2494830_-\|Chromosome-(plasmid)-partitioning-protein-ParB	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.327e-113
LR134305.1\|VEE69489.1\|2488794_2490675_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.34753e-06
LR134305.1\|VEE69492.1\|2492506_2492902_-\|membrane-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	4.93393e-38
LR134305.1\|VEE69499.1\|2499531_2499669_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
LR134305.1\|VEE69496.1\|2495591_2497469_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
LR134305.1\|VEE69495.1\|2494872_2495592_-\|Ribosomal-RNA-small-subunit-methyltransferase-G	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	6.82524e-96
LR134305.1\|VEE69497.1\|2497535_2498915_-\|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
LR134305.1\|VEE69498.1\|2499057_2499405_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	6.56083e-51
LR134305.1\|VEE69503.1\|2503796_2504909_+\|DNA-recombination-and-repair-protein-RecF	gnl\|CDD\|273173	TIGR00611, DNA_replication_and_repair_protein_RecF, recF protein. All proteins in this family for which functions are known are DNA binding proteins that assist the filamentation of RecA onto DNA for the initiation of recombination or recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	1.19174e-172
LR134305.1\|VEE69487.1\|2487244_2487757_-\|membrane-spanning-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	5.06647e-22
LR134305.1\|VEE69484.1\|2484138_2484714_+\|DNA-binding-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	4.72293e-10
LR134305.1\|VEE69493.1\|2492969_2493323_-\|Permease	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	5.87211e-38

>LR134305.1|VEE69493.1|2492969_2493323_-|Permease
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLASLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>LR134305.1|VEE69492.1|2492506_2492902_-|membrane-protein
MKLTLMKFFVGGFAVLLSYIVSVALPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>LR134305.1|VEE69491.1|2491677_2492247_-|helix-turn-helix-family-protein
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWAYVMLIFMTLAAILTGPLIVYWNWAWGITVMVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISVYLANKFL
>LR134305.1|VEE69490.1|2490766_2490958_+|Uncharacterised-protein
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSTVTTPIIGIPVGLLGGAYYLKRREEKGK
>LR134305.1|VEE69489.1|2488794_2490675_+|ABC-transporter-permease
MTFNHIVFKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTIFMLVIAYILILFQSSLFLKRRSILSMMKDSIKTDVTTAKVTTAEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFTKNYYETITVNNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNIINIHLNKDLVVKGTKNETFRVTQEDKGKVYPLNLSFNSPVVEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKVITYDEMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>LR134305.1|VEE69488.1|2488046_2488805_+|ABC-transporter-ATP-binding-protein
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>LR134305.1|VEE69487.1|2487244_2487757_-|membrane-spanning-protein
MEKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLFVLINGVIQIVYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFWFIFSSIAGLFTFSGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFLFVGVIYVVDALA
>LR134305.1|VEE69486.1|2486136_2486949_+|N-acetyltransferase
MNIAKLENYLQIDSSRYNRPSIEALNYYATRFMLTVPFENIDVQNSKPISINIDALFNKIVRDKRGGFCYELNTFFKTYLQQKGFNPELMSATIHTPGGGRSLNGSHASLVVSINDVFYVTDVGFGDLPLHAIPITSSEHTQPITDISGTFRAIFNNQDKDIFYVQKFENDNWRTKYEAEFKAKCIADFDKNIKYNQTHPDSIFVQHLLITMPQSFDRATMSENHLTLTKAKDGISEKLAVTKDNYQHFLKTYFGLDVTINRIENSDSKS
>LR134305.1|VEE69485.1|2484877_2485894_+|nickel-transport-protein
MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEVDALLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTLDGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFISSIEFDYLGYILVALFLITWLISSLIWKFGRIEHKWSK
>LR134305.1|VEE69484.1|2484138_2484714_+|DNA-binding-protein
MTLPKIGKPATRALNSQGIYTLEAVSQYTKSSLMEMHGVGPKAISILEQALFQHQLHFKTEVHSSLPFLLTGDVSCNHAPKRQQMIDFIVATAALDIELLRSLVTTEFIWSVPGRFDIYGPQILIQELSNHYKEIASLNIQSIITHGCLGSMHGIEILKTGKEIHFAHFFEFENHKKDAKLSKVTSYIVVG
>LR134305.1|VEE69494.1|2493990_2494830_-|Chromosome-(plasmid)-partitioning-protein-ParB
MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR
>LR134305.1|VEE69495.1|2494872_2495592_-|Ribosomal-RNA-small-subunit-methyltransferase-G
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHNVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>LR134305.1|VEE69496.1|2495591_2497469_-|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA
MAQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDVVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>LR134305.1|VEE69497.1|2497535_2498915_-|tRNA-(5-carboxymethylaminomethyl-2-thiouridylate)-synthase
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGNTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>LR134305.1|VEE69498.1|2499057_2499405_-|ribonuclease-P-protein-component
MEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>LR134305.1|VEE69499.1|2499531_2499669_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
>LR134305.1|VEE69500.1|2500399_2501761_+|Chromosomal-replication-initiator-protein-DnaA
MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
>LR134305.1|VEE69501.1|2502040_2503174_+|DNA-polymerase-III-beta-subunit
MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVILTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQFQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETRPVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDNEEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAIDRASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGSLKISFNSKYMMDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY
>LR134305.1|VEE69502.1|2503563_2503800_+|S4-domain-containing-protein-YaaA
MVQEVVVEGDINLGQFLKTEGIIESGGQAKWFLQDVEVLINGVRETRRGKKLEHQDRIDIPELPEDAGSFLIIHQGEQ
>LR134305.1|VEE69503.1|2503796_2504909_+|DNA-recombination-and-repair-protein-RecF
MKLNTLQLENYRNYDEVTLKCHPDVNILIGENAQGKTNLLESIYTLALAKSHRTSNDKELIRFNADYAKIEGELSYRHGTMPLTMFITKKGKQVKVNHLEQSRLTQYIGHLNVVLFAPEDLNIVKGSPQIRRRFIDMELGQISAVYLNDLAQYQRILKQKNNYLKQLQLGQKKDLTMLEVLNQQFAEYAMKVTDKRAHFIQELESLAKPIHAGITNDKEALSLNYLPSLKFDYAQNEAARLEEIMSILSDNMQREKERGISLFGPHRDDISFDVNGMDAQTYGSQGQQRTTALSIKLAEIELMNIEVGEYPILLLDDVLSELDDSRQTHLLSTIQHKVQTFVTTTSVDGIDHEIMNNAKLYRINQGEIIK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	494679-494696	0	1.0
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	836910-836927	0	1.0
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	2160817-2160834	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	329729-329759	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	527224-527254	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	527282-527312	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	736190-736220	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	736248-736278	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1047747-1047777	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1123163-1123193	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1123221-1123251	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1123278-1123308	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	2034964-2034994	0	1.0
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	2054100-2054130	0	1.0
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	329882-329907	0	1.0
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	1324244-1324269	0	1.0
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	2054250-2054275	0	1.0
LR134305_1	1.1\|575123\|39\|LR134305\|PILER-CR	575123-575161	39	LR134305.1	247552-247590	1	0.974
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	1489025-1489042	1	0.944
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	575021-575051	1	0.968
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1324207-1324237	1	0.968
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	2493666-2493696	1	0.968
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	2493724-2493754	1	0.968
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	1853617-1853642	1	0.962
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	247438-247473	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	329900-329935	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	1324262-1324297	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	1789270-1789305	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	2054212-2054247	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	2054268-2054303	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	2190149-2190184	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	2553252-2553287	2	0.944
LR134305_1	1.2\|575182\|36\|LR134305\|PILER-CR	575182-575217	36	LR134305.1	2642833-2642868	2	0.944
LR134305_7	7.1\|2019509\|18\|LR134305\|CRT	2019509-2019526	18	LR134305.1	583757-583774	2	0.889
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	166392-166409	2	0.889
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	371545-371562	2	0.889
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	1433900-1433917	2	0.889
LR134305_7	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	LR134305.1	1649430-1649447	2	0.889
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	247554-247584	2	0.935
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	640332-640362	2	0.935
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1343809-1343839	2	0.935
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	LR134305.1	1433908-1433938	2	0.935
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	1343890-1343915	2	0.923
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	1343913-1343938	2	0.923
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	2054194-2054219	2	0.923
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	2160860-2160885	2	0.923
LR134305_10	10.1\|2493577\|26\|LR134305\|CRISPRCasFinder	2493577-2493602	26	LR134305.1	2190177-2190202	2	0.923

1. spacer 7.2|2019568|18|LR134305|CRT matches to position: 494679-494696, mismatch: 0, identity: 1.0

ctttttgaaattctctat	CRISPR spacer
ctttttgaaattctctat	Protospacer
******************

2. spacer 7.2|2019568|18|LR134305|CRT matches to position: 836910-836927, mismatch: 0, identity: 1.0

ctttttgaaattctctat	CRISPR spacer
ctttttgaaattctctat	Protospacer
******************

3. spacer 7.2|2019568|18|LR134305|CRT matches to position: 2160817-2160834, mismatch: 0, identity: 1.0

ctttttgaaattctctat	CRISPR spacer
ctttttgaaattctctat	Protospacer
******************

4. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 329729-329759, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

5. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 527224-527254, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

6. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 527282-527312, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

7. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 736190-736220, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

8. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 736248-736278, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

9. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1047747-1047777, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

10. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1123163-1123193, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

11. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1123221-1123251, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

12. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1123278-1123308, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

13. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 2034964-2034994, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

14. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 2054100-2054130, mismatch: 0, identity: 1.0

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcattgcctgtagaatttcttttcgaaa	Protospacer
*******************************

15. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 329882-329907, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

16. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 1324244-1324269, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

17. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 2054250-2054275, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

18. spacer 1.1|575123|39|LR134305|PILER-CR matches to position: 247552-247590, mismatch: 1, identity: 0.974

gatttcgaaaagaaattctacaaacaatgcaagttgggg	CRISPR spacer
gatttcgaaaagaaattctacagacaatgcaagttgggg	Protospacer
**********************.****************

19. spacer 7.2|2019568|18|LR134305|CRT matches to position: 1489025-1489042, mismatch: 1, identity: 0.944

ctttttgaaattctctat	CRISPR spacer
cttttcgaaattctctat	Protospacer
*****.************

20. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 575021-575051, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
ctcgcactgcctgtagaatttcttttcgaaa	Protospacer
******.************************

21. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1324207-1324237, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttcttttcgaaa	Protospacer
**.****************************

22. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 2493666-2493696, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttcttttcgaaa	Protospacer
**.****************************

23. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 2493724-2493754, mismatch: 1, identity: 0.968

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttcttttcgaaa	Protospacer
**.****************************

24. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 1853617-1853642, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

25. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 247438-247473, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctgtcggaaagtcagcatacaataatgtgcaagtt	Protospacer
**** ******* ***********************

26. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 329900-329935, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

27. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 1324262-1324297, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

28. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 1789270-1789305, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

29. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 2054212-2054247, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

30. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 2054268-2054303, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

31. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 2190149-2190184, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

32. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 2553252-2553287, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

33. spacer 1.2|575182|36|LR134305|PILER-CR matches to position: 2642833-2642868, mismatch: 2, identity: 0.944

gctggcggaaaggcagcatacaataatgtgcaagtt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
************ **** ******************

34. spacer 7.1|2019509|18|LR134305|CRT matches to position: 583757-583774, mismatch: 2, identity: 0.889

acttttgtcagcttctgt	CRISPR spacer
acctttgtcagcttcagt	Protospacer
**.************ **

35. spacer 7.2|2019568|18|LR134305|CRT matches to position: 166392-166409, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
cttttttaaattctccat	Protospacer
****** ********.**

36. spacer 7.2|2019568|18|LR134305|CRT matches to position: 371545-371562, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
cttttcgaaattctttat	Protospacer
*****.********.***

37. spacer 7.2|2019568|18|LR134305|CRT matches to position: 1433900-1433917, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
cttttcgaaattctccat	Protospacer
*****.*********.**

38. spacer 7.2|2019568|18|LR134305|CRT matches to position: 1649430-1649447, mismatch: 2, identity: 0.889

ctttttgaaattctctat	CRISPR spacer
ctttttgaagttctatat	Protospacer
*********.**** ***

39. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 247554-247584, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgtctgtagaatttcttttcgaaa	Protospacer
**.******.*********************

40. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 640332-640362, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcttgtagaatttcttttcgaaa	Protospacer
**.*******.********************

41. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1343809-1343839, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgcctgtagaatttctttacgaaa	Protospacer
**.********************** *****

42. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to position: 1433908-1433938, mismatch: 2, identity: 0.935

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cttgcattgtctgtagaatttcttttcgaaa	Protospacer
**.******.*********************

43. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 1343890-1343915, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctatgttgggaccccg	Protospacer
***.****************.*****

44. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 1343913-1343938, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctgtgttggggccccg	Protospacer
***.********.*************

45. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 2054194-2054219, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttgcggccccg	Protospacer
************.***** *******

46. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 2160860-2160885, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctgtgttggggccccg	Protospacer
***.********.*************

47. spacer 10.1|2493577|26|LR134305|CRISPRCasFinder matches to position: 2190177-2190202, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagctactgtgttggggccccg	Protospacer
********* **.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134305_4	4.1\|752427\|29\|LR134305\|CRISPRCasFinder	752427-752455	29	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	703321-703349	6	0.793
LR134305_9	9.1\|2464252\|31\|LR134305\|CRISPRCasFinder	2464252-2464282	31	NZ_CP009619	Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence	270870-270900	8	0.742

1. spacer 4.1|752427|29|LR134305|CRISPRCasFinder matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 6, identity: 0.793

taaaagagggatacttgcgctgagcgcat	CRISPR spacer
gatcaaagggttccttgcgctgagcgcat	Protospacer
 *  *.**** * ****************

2. spacer 9.1|2464252|31|LR134305|CRISPRCasFinder matches to NZ_CP009619 (Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
gctgcattacctgtagcatttcttttttcaa	Protospacer
 ..*****.******* *********.  **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

14061 : 58985

Staphylococcus_phage(74.6%)

holin,integrase,protease,head,tail,terminase,capsid,portal

attL 13950:13968|attR 61155:61173

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
13950:13968	attL	NA	NA	NA	NA
VEE67182.1\|14061_15267_-\|integrase	phage integrase family protein	A0A1X9H094	Staphylococcus_phage	1.7e-217	97.5
VEE67183.1\|15369_16020_-\|protease	CAAX amino terminal protease	NA	NA	NA	NA
VEE67184.1\|16492_16927_-	lipoprotein	A0A2K9VBS2	Staphylococcus_phage	1.2e-24	98.6
VEE67185.1\|16944_17415_-	phiSLT ORF153-like protein	A0A2I6PEK4	Staphylococcus_phage	5.3e-87	99.4
VEE67186.1\|17418_17748_-	phage repressor	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
VEE67187.1\|17908_18100_+	phage regulatory protein	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
VEE67188.1\|18187_18364_+	Uncharacterised protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
VEE67189.1\|18360_18591_-	phiSLT ORF78-like protein	A0A0H3U2T9	Staphylococcus_phage	6.1e-36	98.7
VEE67190.1\|18647_19400_+	antirepressor	S4SW96	Staphylococcus_phage	2.1e-138	99.2
VEE67191.1\|19415_19613_+	phage protein	A7TWF5	Staphylococcus_phage	1.9e-22	93.8
VEE67192.1\|19758_20022_+	DNA-binding protein	B7T0G2	Staphylococcus_virus	1.1e-44	98.9
VEE67193.1\|20034_20196_+	phage protein	A9CR58	Staphylococcus_phage	1.1e-20	98.1
VEE67194.1\|20298_20601_+	phage like protein	A0A0F6N3N3	Staphylococcus_phage	1.0e-30	68.0
VEE67195.1\|20605_20866_+	phage protein	A1KWZ6	Staphylococcus_virus	1.2e-40	94.2
VEE67196.1\|20875_21097_+	phage protein	A0A1X9H047	Staphylococcus_phage	1.2e-33	100.0
VEE67197.1\|21089_21713_+	putative phage topoisomerase	A0A2H4PQQ6	Staphylococcus_phage	2.3e-114	99.5
VEE67198.1\|21712_22132_+	prophage L54a, single-stranded DNA binding protein	Q4ZA54	Staphylococcus_virus	1.4e-62	100.0
VEE67199.1\|22145_22841_+	phage protein	A0A0E3XBQ6	Staphylococcus_phage	1.6e-127	93.9
VEE67200.1\|22812_23613_+	phi PV83 orf 20-like protein	Q4ZBE3	Staphylococcus_virus	8.7e-106	98.5
VEE67201.1\|23612_23969_+	phage protein	M9NS37	Staphylococcus_phage	8.2e-64	100.0
VEE67202.1\|23965_25207_+	prophage L54a, replicative DNA helicase	Q4ZCW6	Staphylococcus_virus	2.6e-226	98.8
VEE67203.1\|25203_25419_+	hypothetical phage-related protein	Q4ZAY6	Staphylococcus_virus	8.2e-35	98.6
VEE67204.1\|25422_25644_+	putative phi ETA-like protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
VEE67205.1\|25653_26058_+	putative phi ETA-like protein	G4KNP2	Staphylococcus_phage	1.6e-68	100.0
VEE67206.1\|26062_26248_+	Protein of uncharacterised function (DUF3113)	A0A2H4JAM6	uncultured_Caudovirales_phage	5.4e-27	100.0
VEE67207.1\|26248_26617_+	Phage protein	A0A0H4J337	Staphylococcus_phage	2.0e-52	100.0
VEE67208.1\|26620_26863_+	phage conserved Open Reading Frame 51	Q4ZBD5	Staphylococcus_virus	1.9e-40	98.8
VEE67209.1\|26876_27287_+	putative phage PVL protein	A0A1P8CN10	Staphylococcus_phage	6.1e-47	68.4
VEE67210.1\|27286_27562_+	Phage protein	Q4ZA41	Staphylococcus_virus	1.3e-45	100.0
VEE67211.1\|27554_27803_+	Phage protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
VEE67212.1\|27795_28332_+	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	1.4e-94	99.4
VEE67213.1\|28368_28653_+	Uncharacterised protein	NA	NA	NA	NA
VEE67214.1\|28669_28876_+	Uncharacterised protein	NA	NA	NA	NA
VEE67215.1\|28872_29079_+	phage protein	Q4ZCV6	Staphylococcus_virus	7.1e-20	98.5
VEE67216.1\|29075_29228_+	transcriptional activator rinB-like protein	B7T0I1	Staphylococcus_virus	1.2e-19	98.0
VEE67217.1\|29295_29496_+	putative exported phage protein	A0A2I6PEG6	Staphylococcus_phage	5.5e-25	97.0
VEE67218.1\|29544_31992_+	E family protein	B7T0I3	Staphylococcus_virus	0.0e+00	98.2
VEE67219.1\|32332_32623_+	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
VEE67220.1\|32612_33971_+	putative DNA helicase	M9QRT1	Staphylococcus_phage	4.4e-259	98.7
VEE67221.1\|33983_34421_+	phage regulatory protein	A0A2I6PEN3	Staphylococcus_phage	3.0e-76	99.3
VEE67222.1\|34577_34892_+	HNH endonuclease family protein	M9QQL5	Staphylococcus_phage	2.5e-56	100.0
VEE67223.1\|35019_35325_+\|terminase	Phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
VEE67224.1\|35314_37006_+\|terminase	terminase large subunit	Q4ZD20	Staphylococcus_virus	0.0e+00	99.1
VEE67225.1\|37010_38249_+\|portal	portal protein	A0A2I6PER5	Staphylococcus_phage	7.6e-234	99.5
VEE67226.1\|38232_39006_+\|protease	phage protease	A0A2I6PEQ7	Staphylococcus_phage	3.9e-135	98.4
VEE67227.1\|39017_40181_+\|capsid	putative phage capsid protein	A0A2I6PDD7	Staphylococcus_phage	1.5e-215	99.0
VEE67228.1\|40249_40528_+\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PEQ1	Staphylococcus_phage	6.0e-46	98.9
VEE67229.1\|40539_40872_+	phage protein	M9QX19	Staphylococcus_phage	2.4e-57	99.1
VEE67230.1\|40868_41270_+	putative phiSLT protein	A0A0K1LL98	Staphylococcus_phage	1.1e-67	100.0
VEE67231.1\|41270_41666_+	phage protein	A0A0K1LKC0	Staphylococcus_phage	1.5e-66	99.2
VEE67232.1\|41700_42342_+\|tail	major tail protein	A0A2I6PEP6	Staphylococcus_phage	1.8e-117	98.1
VEE67233.1\|42433_42889_+\|tail	major tail protein	Q9B0D4	Staphylococcus_phage	1.2e-75	98.0
VEE67234.1\|42915_43266_+	putative gp48	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
VEE67235.1\|43307_43466_+	putative gp49	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
VEE67236.1\|43479_46527_+\|tail	Phage tail length tape-measure protein	A0A0K1LKC4	Staphylococcus_phage	0.0e+00	98.5
VEE67237.1\|46523_49679_+\|tail	Phage tail length tape-measure protein	M9QQM6	Staphylococcus_phage	0.0e+00	98.8
VEE67238.1\|49678_50503_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.6e-158	99.6
VEE67239.1\|50511_52095_+\|tail	prophage endopeptidase tail family protein	Q4ZD01	Staphylococcus_virus	4.3e-306	99.2
VEE67240.1\|52094_52385_+	putative gp53	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
VEE67241.1\|52400_54311_+	putative minor structural protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	99.4
VEE67242.1\|54310_55777_+\|tail	putative phage tail protein	A0A2I6PDQ5	Staphylococcus_phage	1.8e-250	97.5
VEE67243.1\|55776_56166_+	phage-like protein	Q4ZCZ7	Staphylococcus_virus	6.4e-62	96.9
VEE67244.1\|56158_56323_+	phage protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
VEE67245.1\|56368_56668_+	hypothetical phage-related protein	M9QRV2	Staphylococcus_phage	2.2e-30	98.0
VEE67246.1\|57216_57519_+\|holin	holin	B7T0L0	Staphylococcus_virus	3.8e-46	94.0
VEE67247.1\|57530_58985_+	amidase	A0A0N6WMR3	Staphylococcus_phage	1.4e-279	95.9
61155:61173	attR	NA	NA	NA	NA

DBSCAN-SWA_2

124157 : 136013

Streptococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE67315.1\|124157_125624_+	Inosine-5-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
VEE67316.1\|125648_127190_+	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	1.2e-23	32.6
VEE67317.1\|127283_128420_-	Integrase	A0A1S5S7K9	Streptococcus_phage	1.0e-75	42.5
VEE67318.1\|128503_129289_-	transcriptional regulator	A0A1S5S8T5	Streptococcus_phage	1.2e-09	58.6
VEE67319.1\|129405_129633_+	phage protein	NA	NA	NA	NA
VEE67320.1\|129678_129939_+	pathogenicity island protein	NA	NA	NA	NA
VEE67321.1\|129985_130132_+	pathogenicity island protein	NA	NA	NA	NA
VEE67322.1\|130349_130643_+	pathogenicity island protein	A0A1W6JQH0	Staphylococcus_phage	1.7e-14	46.1
VEE67323.1\|130733_133097_+	primase	A0A2H4JCU9	uncultured_Caudovirales_phage	1.3e-136	39.1
VEE67324.1\|133518_133863_+	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	4.2e-41	65.2
VEE67325.1\|134087_134294_+	pathogenicity island protein	NA	NA	NA	NA
VEE67326.1\|134280_135339_+	pahtogenicity island protein	NA	NA	NA	NA
VEE67327.1\|135521_136013_+	pathogenicity island protein	A0A2H4JB26	uncultured_Caudovirales_phage	2.3e-24	40.5

DBSCAN-SWA_3

459125 : 466946

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE67615.1\|459125_460181_-	Sensor histidine protein kinase SaeS (exoprotein expression protein S)	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
VEE67616.1\|460180_460867_-	Response regulator SaeR	NA	NA	NA	NA
VEE67617.1\|460841_461315_-	DoxX family protein	NA	NA	NA	NA
VEE67618.1\|461657_462098_-	lipoprotein	NA	NA	NA	NA
VEE67619.1\|462377_462962_-	Uncharacterised protein	NA	NA	NA	NA
VEE67620.1\|463060_463774_-	Queuosine Biosynthesis QueE Radical SAM	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
VEE67621.1\|463777_464197_-	6-pyruvoyl-tetrahydropterin synthase	S4U060	uncultured_phage	6.3e-07	28.7
VEE67622.1\|464198_464867_-	Queuosine Biosynthesis QueC ATPase	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
VEE67623.1\|465217_465811_+	Para-aminobenzoate synthase, amidotransferase component PabAb	A0A0P0IKJ1	Acinetobacter_phage	5.8e-38	42.9
VEE67624.1\|465794_466946_+	Para-aminobenzoate synthetase component I	S4VNU7	Pandoravirus	9.2e-24	36.5

DBSCAN-SWA_4

478918 : 493354

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE67633.1\|478918_479977_+	histidinol-phosphate aminotransferase	A0A0H3TLT9	Faustovirus	1.1e-20	27.3
VEE67634.1\|480374_480923_+	5'-3'-deoxyribonucleotidase, putative	NA	NA	NA	NA
VEE67635.1\|481525_482443_-	Transcription regulator (contains diacylglycerol kinase catalytic domain)	A0A1V0SBJ0	Catovirus	1.6e-07	22.8
VEE67636.1\|482724_484230_-	Di/tripeptide permease YjdL	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
VEE67637.1\|484569_485070_-	NADPH dependent preQ0 reductase	E7DN65	Pneumococcus_phage	2.2e-51	70.8
VEE67638.1\|485089_485956_-	Integral membrane domain protein	NA	NA	NA	NA
VEE67639.1\|486756_487155_+	Nrdi	A0A2H4J545	uncultured_Caudovirales_phage	4.3e-53	72.7
VEE67640.1\|487117_489223_+	ribonucleotide-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
VEE67641.1\|489340_490312_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
VEE67642.1\|490639_491653_+	FatD	A0A2H4IY97	uncultured_Caudovirales_phage	2.2e-138	78.0
VEE67643.1\|491639_492596_+	Iron compound ABC uptake transporter permease protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
VEE67644.1\|492592_493354_+	Iron compound ABC uptake transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	5.0e-18	31.6

DBSCAN-SWA_5

737624 : 746097

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE67874.1\|737624_738107_+	AIR carboxylase	A0A2P0VNU7	Tetraselmis_virus	3.4e-20	43.3
VEE67875.1\|738093_739926_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	2.1e-46	41.2
VEE67876.1\|739925_740189_+	Phosphoribosylformylglycinamidine synthase, PurS subunit	NA	NA	NA	NA
VEE67877.1\|740190_740862_+	Phosphoribosylformylglycinamidine synthase	NA	NA	NA	NA
VEE67878.1\|740854_743044_+	Phosphoribosylformylglycinamidine synthase, synthetase subunit	A6N228	Microbacterium_phage	3.0e-140	39.7
VEE67879.1\|743022_744507_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
VEE67880.1\|744499_745528_+	Phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.2e-61	41.1
VEE67881.1\|745530_746097_+	Phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_6

1281278 : 1289590

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE68357.1\|1281278_1282064_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-18	27.9
VEE68358.1\|1282189_1283080_-	endonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
VEE68359.1\|1283089_1284436_-	ATP-dependent RNA helicase YqfR	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
VEE68360.1\|1284549_1285650_-	NIF3 protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
VEE68361.1\|1285652_1286330_-\|tRNA	Putative tRNA-m1A22 methylase	NA	NA	NA	NA
VEE68362.1\|1286460_1287567_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
VEE68363.1\|1287790_1289590_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_7

1358996 : 1368039

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE68434.1\|1358996_1359515_-	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.6e-28	45.8
VEE68435.1\|1359536_1361810_-	Single-stranded-DNA-specific exonuclease recJ	A7KV88	Bacillus_phage	1.1e-63	29.3
VEE68436.1\|1362012_1364292_-	Protein-export membrane protein secD / Protein-export membrane protein secF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
VEE68437.1\|1364566_1364827_-	Preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
VEE68438.1\|1364845_1365985_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
VEE68439.1\|1366007_1367033_-\|tRNA	S-adenosylmethionine--tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
VEE68440.1\|1367034_1368039_-	Holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1493783 : 1571514

Staphylococcus_phage(91.53%)

integrase,protease,tRNA,bacteriocin,transposase

attL 1559480:1559498|attR 1578276:1578294

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE68545.1\|1493783_1500341_-	LPXTG-motif cell wall anchor domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	5.5e-307	96.7
VEE68546.1\|1500667_1500979_-	Rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
VEE68547.1\|1501000_1503418_-\|tRNA	Leucyl-tRNA synthetase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.8
VEE68548.1\|1503705_1504887_-	Multidrug resistance protein	A0A2H4PQR6	Staphylococcus_phage	4.7e-217	99.2
VEE68549.1\|1504996_1505950_+	Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
VEE68550.1\|1505946_1506510_+	SAM-dependent methyltransferase, MraW methylase family	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
VEE68551.1\|1506629_1507031_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
VEE68552.1\|1507601_1508429_-	Lysophospholipase; Monoglyceride lipase; putative	NA	NA	NA	NA
VEE68553.1\|1508662_1509664_+	Proline dehydrogenase (Proline oxidase)	A0A2H4PQT6	Staphylococcus_phage	2.0e-184	99.4
VEE68554.1\|1509785_1510250_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
VEE68555.1\|1510262_1511444_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
VEE68556.1\|1511454_1512087_-	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
VEE68557.1\|1512093_1513137_-	5-amino-6-(5-phosphoribosylamino)uracil reductase	A0A2H4PQS8	Staphylococcus_phage	3.5e-195	98.5
VEE68558.1\|1513620_1515120_-	pyridine nucleotide-disulfide oxidoreductase family protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
VEE68559.1\|1515641_1515956_+	arsenical resistance operon repressor 2	A0A2H4PQT4	Staphylococcus_phage	1.3e-52	98.1
VEE68560.1\|1515955_1517248_+	arsenical pump membrane protein	A0A2H4PQU3	Staphylococcus_phage	2.6e-224	97.4
VEE68561.1\|1517265_1517661_+	arsenate reductase, putative	A0A2H4PQT9	Staphylococcus_phage	2.4e-72	99.2
VEE68562.1\|1518010_1518865_-	peptidoglycan endo-beta-N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
VEE68563.1\|1519140_1519365_-	putative staphylococcal protein	NA	NA	NA	NA
VEE68564.1\|1519563_1520034_+	RNA polymerase sigma factor sigS	A0A2H4PQT5	Staphylococcus_phage	4.8e-80	96.8
VEE68565.1\|1520146_1520590_+	comK family protein	NA	NA	NA	NA
VEE68566.1\|1520576_1521020_-	putative staphylococcal protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
VEE68567.1\|1521317_1521953_+\|protease	CAAX amino terminal protease	NA	NA	NA	NA
VEE68568.1\|1522389_1523103_-	Transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
VEE68569.1\|1523360_1523663_+	membrane protein	NA	NA	NA	NA
VEE68570.1\|1523918_1524284_+	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	2.4e-58	97.5
VEE68571.1\|1524280_1524634_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.2e-20	94.0
VEE68572.1\|1524883_1525717_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	6.0e-158	99.3
VEE68573.1\|1525928_1526837_-	Uncharacterised protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
VEE68574.1\|1526961_1528155_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
VEE68575.1\|1528525_1530118_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
VEE68576.1\|1530412_1531183_-	Dipeptidyl aminopeptidase/acylaminoacyl-peptidase	A0A2H4PQM6	Staphylococcus_phage	2.0e-139	96.8
VEE68577.1\|1531163_1531643_-	phosphohydrolase	A0A2H4PQM4	Staphylococcus_phage	4.3e-84	98.1
VEE68578.1\|1531702_1531960_+	Putative cytosolic protein	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
VEE68579.1\|1531956_1532958_-	O-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.1e-185	97.0
VEE68580.1\|1532962_1534441_-	O-succinylbenzoic acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	9.3e-279	95.9
VEE68581.1\|1534599_1535082_-	putative lipoprotein	A0A2H4PQN7	Staphylococcus_phage	8.4e-80	99.3
VEE68582.1\|1535393_1536008_+	endonuclease	A0A2H4PQM8	Staphylococcus_phage	3.7e-40	84.3
VEE68583.1\|1536088_1537084_+	Telomeric repeat-binding factor 2	A0A2H4PQN2	Staphylococcus_phage	5.6e-70	95.6
VEE68584.1\|1537159_1537786_+	lipoprotein	A0A2H4PQM7	Staphylococcus_phage	4.2e-79	81.7
VEE68585.1\|1537826_1538168_+	Uncharacterised protein	A0A2H4PQN6	Staphylococcus_phage	2.3e-55	95.6
VEE68586.1\|1538268_1538841_+	Uncharacterised protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
VEE68587.1\|1539216_1540053_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
VEE68588.1\|1540040_1540745_+	ABC transporter permease	NA	NA	NA	NA
VEE68589.1\|1540858_1541305_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
VEE68590.1\|1541386_1541611_-\|transposase	transposase	NA	NA	NA	NA
VEE68591.1\|1542427_1542802_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
VEE68592.1\|1542791_1543172_-	Protein of uncharacterised function (DUF1433)	NA	NA	NA	NA
VEE68593.1\|1543379_1543820_-	putative protein with DUF1433	NA	NA	NA	NA
VEE68594.1\|1543864_1545478_+	pathogenicity island protein	NA	NA	NA	NA
VEE68595.1\|1545492_1545792_+	ESAT-6 family protein	NA	NA	NA	NA
VEE68596.1\|1546028_1547207_-	Type I restriction-modification system, specificity subunit S	A0A2H4PQP5	Staphylococcus_phage	5.0e-41	35.4
VEE68597.1\|1547199_1548756_-	Type I restriction enzyme EcoprrI M protein	A0A2H4PQP4	Staphylococcus_phage	5.7e-287	97.5
VEE68598.1\|1549119_1549839_-\|protease	Serine protease splD	A0A2H4PQP1	Staphylococcus_phage	2.6e-125	94.6
VEE68599.1\|1549964_1550684_-\|protease	Serine protease splC	A0A2H4PQP7	Staphylococcus_phage	5.1e-121	91.6
VEE68600.1\|1550741_1551464_-\|protease	Serine protease splB	A0A2H4PQN0	Staphylococcus_phage	8.7e-129	96.7
VEE68601.1\|1551588_1551918_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.2e-55	96.3
VEE68602.1\|1552085_1552295_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	4.4e-25	92.4
VEE68603.1\|1553259_1553823_+	beta-lactamase	A0A2H4PQH6	Staphylococcus_phage	5.6e-51	62.4
VEE68604.1\|1554296_1554995_-	lantibiotic ABC transporter protein	A0A2H4PQH0	Staphylococcus_phage	7.1e-112	93.1
VEE68605.1\|1554991_1555753_-	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family protein	A0A2H4PQH2	Staphylococcus_phage	2.5e-126	94.9
VEE68606.1\|1555749_1556442_-	lantibiotic immunity protein F	A0A2H4PQG7	Staphylococcus_phage	1.4e-120	97.4
VEE68607.1\|1556464_1557838_-\|protease	epidermin leader peptide processing serine protease EpiP	A0A2H4PQH1	Staphylococcus_phage	9.7e-246	94.5
VEE68608.1\|1557847_1558366_-	lantibiotic modifying enzyme	A0A2H4PQG9	Staphylococcus_phage	1.9e-93	97.7
VEE68609.1\|1558381_1559626_-	Epidermin biosynthesis protein epiC	A0A2H4PQH9	Staphylococcus_phage	1.2e-210	88.6
1559480:1559498	attL	NA	NA	NA	NA
VEE68610.1\|1559618_1562612_-\|bacteriocin	thiopeptide-type bacteriocin biosynthesis domain protein	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	92.4
VEE68611.1\|1562676_1562820_-	lantibiotic protein	A0A2H4PQH4	Staphylococcus_phage	3.8e-20	100.0
VEE68612.1\|1563583_1564372_-	insertion element protein	A0A0C5AEA5	Paenibacillus_phage	5.7e-49	51.4
VEE68613.1\|1564395_1565124_-\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0
VEE68614.1\|1565218_1565362_-	lantibiotic protein	A0A2H4PQH4	Staphylococcus_phage	9.9e-13	76.6
VEE68615.1\|1565604_1566588_-	Leukotoxin LukD	A0A2H4PQH7	Staphylococcus_phage	2.6e-184	98.2
VEE68616.1\|1566589_1566856_-	Leukocidin S subunit lukE	A0A2H4PQI5	Staphylococcus_phage	4.9e-45	100.0
VEE68617.1\|1566988_1567525_-	Leukocidin S subunit lukE	A0A2H4PQI5	Staphylococcus_phage	9.7e-93	100.0
VEE68618.1\|1568252_1568702_+	Uncharacterised protein	NA	NA	NA	NA
VEE68619.1\|1568722_1569499_+	Domain of uncharacterised function DUF1828	NA	NA	NA	NA
VEE68620.1\|1569894_1570389_+	Uncharacterised protein	NA	NA	NA	NA
VEE68621.1\|1570464_1571514_+\|integrase	putative integrase	A0A2H4JB53	uncultured_Caudovirales_phage	1.3e-181	89.4
1578276:1578294	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1599038 : 1675874

Staphylococcus_phage(63.38%)

holin,integrase,protease,head,tail,terminase,tRNA,transposase,capsid,portal

attL 1641706:1641720|attR 1677431:1677445

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE68646.1\|1599038_1599509_-\|tRNA	tRNA (cytosine34-2-O-)-methyltransferase	NA	NA	NA	NA
VEE68647.1\|1599513_1600641_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
VEE68648.1\|1600791_1601520_-	Glutamine transport ATP-binding protein glnQ	G9BWD6	Planktothrix_phage	1.0e-36	42.7
VEE68649.1\|1601506_1602964_-	extracellular glutamine-binding protein	NA	NA	NA	NA
VEE68650.1\|1603221_1604283_-	Regulatory protein	NA	NA	NA	NA
VEE68651.1\|1613153_1613600_-	Peroxide stress regulator PerR, FUR family	NA	NA	NA	NA
VEE68652.1\|1613696_1614656_-	D-3-phosphoglycerate dehydrogenase	NA	NA	NA	NA
VEE68653.1\|1614652_1615108_-	Thiol peroxidase, Bcp-type	NA	NA	NA	NA
VEE68654.1\|1615188_1616478_+	Glutamate-1-semialdehyde aminotransferase	NA	NA	NA	NA
VEE68655.1\|1616719_1617865_+	integral membrane protein	NA	NA	NA	NA
VEE68656.1\|1618054_1619791_-	Lipid A export ATP-binding/permease protein MsbA	W8CYL7	Bacillus_phage	1.7e-53	30.4
VEE68657.1\|1620082_1620625_-	Putative cytosolic protein	NA	NA	NA	NA
VEE68658.1\|1620927_1621965_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
VEE68659.1\|1622116_1623094_+	membrane-bound metal-dependent hydrolase	NA	NA	NA	NA
VEE68660.1\|1623354_1624191_-	Teichoic acid translocation permease protein TagG	NA	NA	NA	NA
VEE68661.1\|1624199_1625717_-	Teichoic acid export ATP-binding protein TagH	NA	NA	NA	NA
VEE68662.1\|1625731_1626046_-	transcriptional regulator	NA	NA	NA	NA
VEE68663.1\|1626023_1626842_-	Regulatory protein recX	NA	NA	NA	NA
VEE68664.1\|1627102_1627912_-	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
VEE68665.1\|1628205_1628934_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0
VEE68666.1\|1628957_1629746_+	insertion element protein	A0A0C5AEA5	Paenibacillus_phage	5.7e-49	51.4
VEE68667.1\|1629914_1630430_-	ThiJ/PfpI family protein	NA	NA	NA	NA
VEE68668.1\|1630559_1630721_-	Putative cytosolic protein	NA	NA	NA	NA
VEE68669.1\|1631193_1632195_-	BcgI-like restriction enzyme subunit beta	A0A1W6JNN3	Staphylococcus_phage	1.0e-55	40.1
VEE68670.1\|1632178_1634071_-	BcgI-like restriction enzyme subunit alpha	A0A1W6JNK1	Staphylococcus_phage	5.6e-268	70.9
VEE68671.1\|1634582_1635551_-	Panton-Valentine leukocidin LukF-PV chain precursor	Q9MBN2	Staphylococcus_prophage	2.0e-181	100.0
VEE68672.1\|1635552_1636479_-	leukocidin chain lukM precursor	Q9MBN3	Staphylococcus_prophage	4.2e-176	99.7
VEE68673.1\|1636826_1637582_-	Autolysin	Q9MBN4	Staphylococcus_prophage	3.4e-152	100.0
VEE68674.1\|1637593_1637848_-\|holin	Phage holin	Q9MBN5	Staphylococcus_prophage	5.3e-41	100.0
VEE68675.1\|1638386_1638617_-	phage protein	D2JLG2	Staphylococcus_phage	2.6e-31	98.7
VEE68676.1\|1638740_1639028_-	phage protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
VEE68677.1\|1639074_1639227_-	phage protein	D2JLG0	Staphylococcus_phage	1.2e-19	98.0
VEE68678.1\|1639216_1643002_-	phage minor structural protein	D2JLF9	Staphylococcus_phage	0.0e+00	97.3
1641706:1641720	attL	NA	NA	NA	NA
VEE68679.1\|1643017_1644508_-\|tail	phage tail family protein	D2JLF8	Staphylococcus_phage	1.4e-295	99.0
VEE68680.1\|1644507_1649181_-\|tail	phage tail tape measure protein, TP901 family, core region	A0A1V0E5H1	Staphylococcus_phage	0.0e+00	97.5
VEE68681.1\|1649319_1649766_-	Bacteriophage	D2JLF5	Staphylococcus_phage	1.2e-72	99.3
VEE68682.1\|1649830_1650784_-\|tail	phage major tail, phi13 family protein	A7TWD0	Staphylococcus_phage	2.5e-168	95.6
VEE68683.1\|1650784_1651165_-	phi PVL orf 12-like protein	D2JLF3	Staphylococcus_phage	5.8e-68	100.0
VEE68684.1\|1651161_1651539_-	gp10 family phage protein	D2JLF2	Staphylococcus_phage	4.0e-61	99.2
VEE68685.1\|1651538_1651874_-\|head,tail	phage head-tail adaptor	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
VEE68686.1\|1651860_1652193_-\|head,tail	phage gp6-like head-tail connector family protein	D2JLF0	Staphylococcus_phage	6.2e-58	99.1
VEE68687.1\|1652201_1652360_-	Bacteriophage	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
VEE68688.1\|1652395_1653643_-\|capsid	phage major capsid protein, HK97 family	Q8SDK8	Staphylococcus_phage	1.1e-208	97.3
VEE68689.1\|1653730_1654315_-\|head,protease	prohead protease	D2JLE7	Staphylococcus_phage	2.9e-106	99.5
VEE68690.1\|1654307_1655558_-\|portal	portal protein	D2JLE6	Staphylococcus_phage	3.7e-236	99.5
VEE68691.1\|1655563_1655764_-	phi PVL orf 3-like protein	A0A1P8L6D3	Staphylococcus_phage	4.9e-26	97.0
VEE68692.1\|1655777_1657472_-	phage Terminase family protein	D2JLE4	Staphylococcus_phage	0.0e+00	99.5
VEE68693.1\|1657474_1657942_-\|terminase	phage terminase small subunit	D2JLE3	Staphylococcus_phage	1.6e-80	98.7
VEE68694.1\|1658070_1658424_-	phage endonuclease	D2JLE2	Staphylococcus_phage	3.3e-65	97.4
VEE68695.1\|1658430_1658883_-	hypothetical phage-related protein	D2JLE1	Staphylococcus_phage	3.9e-79	98.7
VEE68696.1\|1658997_1659459_-	Phage protein	D2JLE0	Staphylococcus_phage	1.1e-68	100.0
VEE68697.1\|1659481_1659682_-	phage protein	D2JLD9	Staphylococcus_phage	2.4e-28	98.5
VEE68698.1\|1659681_1660332_-	Uncharacterised protein	D2JLD8	Staphylococcus_phage	3.8e-115	98.1
VEE68699.1\|1660490_1660640_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	1.4e-17	98.0
VEE68700.1\|1660636_1660843_-	Protein of uncharacterised function (DUF1381)	B7T0C2	Staphylococcus_virus	6.0e-19	95.6
VEE68701.1\|1660879_1661221_-	dUTPase family protein	A0A1P8L6E0	Staphylococcus_phage	4.8e-53	100.0
VEE68702.1\|1661213_1661462_-	Phage protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
VEE68703.1\|1661454_1661730_-	Phage protein	Q4ZA41	Staphylococcus_virus	1.3e-45	100.0
VEE68704.1\|1661729_1662140_-	putative phage PVL protein	A0A1P8CN10	Staphylococcus_phage	6.1e-47	68.4
VEE68705.1\|1662142_1662352_-	Phage protein	A0A059T5A6	Staphylococcus_phage	5.9e-30	88.2
VEE68706.1\|1662362_1662611_-	phage family protein	A0A2I6PDI0	Staphylococcus_phage	4.0e-41	95.1
VEE68707.1\|1662611_1662983_-	PVL ORF-50-like family protein	Q9MBR4	Staphylococcus_prophage	1.4e-50	96.7
VEE68708.1\|1662994_1663252_-	helix-turn-helix DNA binding protein	Q9MBR5	Staphylococcus_prophage	5.4e-41	100.0
VEE68709.1\|1663252_1663438_-	PV83 orf 23-like protein	Q9MBR6	Staphylococcus_prophage	1.7e-25	96.7
VEE68710.1\|1663442_1663847_-	hypothetical phage-related protein	A7TWN5	Staphylococcus_phage	3.3e-69	96.3
VEE68711.1\|1663857_1664079_-	putative phi ETA-like protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
VEE68712.1\|1664081_1664297_-	hypothetical phage-related protein	Q4ZA49	Staphylococcus_virus	6.3e-35	100.0
VEE68713.1\|1664293_1665535_-	prophage L54a, replicative DNA helicase	Q4ZA50	Staphylococcus_virus	2.6e-229	99.8
VEE68714.1\|1665531_1665888_-	phage protein	M9NS37	Staphylococcus_phage	8.2e-64	100.0
VEE68715.1\|1665887_1666643_-	hypothetical phage-related protein	B7T0A7	Staphylococcus_virus	1.7e-143	100.0
VEE68716.1\|1666635_1667310_-	phage protein	Q4ZA53	Staphylococcus_virus	2.0e-127	98.2
VEE68717.1\|1667323_1667752_-	phage single-stranded DNA-binding protein	A0A2H4JHI1	uncultured_Caudovirales_phage	1.5e-59	98.6
VEE68718.1\|1667751_1668390_-	putative phage single-strand DNA binding protein	Q9MBS2	Staphylococcus_prophage	1.7e-115	100.0
VEE68719.1\|1668389_1668869_-	phage protein	Q9MBS3	Staphylococcus_prophage	8.1e-83	100.0
VEE68720.1\|1668883_1669144_-	phage protein	Q9MBS4	Staphylococcus_prophage	1.5e-43	100.0
VEE68721.1\|1669238_1669400_-	phage protein	A9CR58	Staphylococcus_phage	3.3e-20	96.2
VEE68722.1\|1669383_1669614_-	phage protein	Q9MBS7	Staphylococcus_prophage	1.5e-31	100.0
VEE68723.1\|1669684_1669897_+	Uncharacterised protein	A0A2H4JBA9	uncultured_Caudovirales_phage	3.2e-15	56.5
VEE68724.1\|1669824_1669989_-	phi PV83 orf 10-like protein	A0A2H4J3T9	uncultured_Caudovirales_phage	9.4e-07	61.1
VEE68725.1\|1670004_1670754_-	putative phage anti-repressor protein	A0A1W6JPN2	Staphylococcus_phage	7.6e-136	99.6
VEE68726.1\|1670814_1671057_+	Uncharacterised protein	Q4ZCA7	Staphylococcus_virus	2.8e-15	50.0
VEE68727.1\|1671004_1671292_-	Uncharacterised protein	NA	NA	NA	NA
VEE68728.1\|1671346_1671556_+	Uncharacterised protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
VEE68729.1\|1671548_1671689_-	phage protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
VEE68730.1\|1671703_1672147_-	hypothetical phage-related protein	W5R971	Staphylococcus_phage	4.1e-73	98.6
VEE68731.1\|1672194_1672407_-	helix-turn-helix family protein	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
VEE68732.1\|1672558_1673290_+	CI-like repressor, phage associated	M9NUL0	Staphylococcus_phage	5.6e-91	72.2
VEE68733.1\|1673301_1673448_+	phage protein	U5U441	Staphylococcus_phage	4.3e-19	100.0
VEE68734.1\|1673444_1673630_+	phage protein	A0A1X9H0K5	Staphylococcus_phage	2.5e-24	98.4
VEE68735.1\|1673665_1674649_+	Protein of uncharacterised function (DUF3644)	A0A0N9RUA4	Staphylococcus_phage	9.9e-168	92.0
VEE68736.1\|1674827_1675874_+\|integrase	phage integrase family protein	Q4ZDS8	Staphylococcus_virus	1.8e-199	98.9
1677431:1677445	attR	NA	NA	NA	NA

DBSCAN-SWA_10

1757803 : 1769310

Staphylococcus_phage(45.45%)

integrase

attL 1749684:1749707|attR 1772446:1772469

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1749684:1749707	attL	NA	NA	NA	NA
VEE68816.1\|1757803_1758295_-	pathogenicity island protein	A0A2H4JB26	uncultured_Caudovirales_phage	3.0e-24	39.9
VEE68817.1\|1758460_1759519_-	pahtogenicity island protein	NA	NA	NA	NA
VEE68818.1\|1759505_1759712_-	pathogenicity island protein	NA	NA	NA	NA
VEE68819.1\|1759936_1760281_-	pathogenicity island protein	A0A1W6JQD5	Staphylococcus_phage	1.2e-40	64.3
VEE68820.1\|1760951_1763324_-	Putative DNA primase	A0A2H4JCU9	uncultured_Caudovirales_phage	6.7e-146	41.3
VEE68821.1\|1763415_1763715_-	bovine pathogenicity island protein Orf16	Q4ZE75	Staphylococcus_phage	5.9e-31	66.7
VEE68822.1\|1763715_1763940_-	pathogenicity island protein	A0A1W6JPA6	Staphylococcus_phage	3.4e-15	60.3
VEE68823.1\|1763929_1764079_-	hypothetical bovine pathogenicity island protein	NA	NA	NA	NA
VEE68824.1\|1764075_1764393_-	mobile element-associated transcriptional regulator, putative	A0A1W6JQE0	Staphylococcus_phage	1.7e-49	96.2
VEE68825.1\|1764406_1765048_-	putative prophage antirepressor	A0A2H4JB17	uncultured_Caudovirales_phage	2.3e-96	82.2
VEE68826.1\|1765051_1765264_-	putative transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	7.9e-06	45.5
VEE68827.1\|1765417_1766080_+	putative transcriptional regulator	NA	NA	NA	NA
VEE68828.1\|1766092_1767265_+\|integrase	mobile element-associated integrase, putative	A0A1W6JQD3	Staphylococcus_phage	3.5e-220	98.5
VEE68829.1\|1767333_1768950_-	heat shock protein 60 family chaperone GroEL	A0A240F779	uncultured_virus	1.2e-157	54.9
VEE68830.1\|1769025_1769310_-	Heat shock protein 60 family co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
1772446:1772469	attR	NA	NA	NA	NA

DBSCAN-SWA_11

2198778 : 2241639

Paenibacillus_phage(14.29%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE69235.1\|2198778_2199507_-\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	2.9e-23	35.0
VEE69236.1\|2199623_2200277_+	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
VEE69237.1\|2200414_2202493_+	Na+/H+ antiporter	NA	NA	NA	NA
VEE69238.1\|2202633_2204463_-	Amino acid permease	NA	NA	NA	NA
VEE69239.1\|2204694_2206194_+	flp protein	NA	NA	NA	NA
VEE69240.1\|2206300_2207152_-	putative NAD-dependent epimerase/dehydratase	NA	NA	NA	NA
VEE69241.1\|2207475_2208411_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
VEE69242.1\|2208636_2210037_-	integral membrane efflux protein	NA	NA	NA	NA
VEE69243.1\|2210329_2211025_-\|holin	putative glycine betaine/carnitine/choline transport system permease protein	NA	NA	NA	NA
VEE69244.1\|2211024_2211966_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, substrate-binding protein OpuCC	NA	NA	NA	NA
VEE69245.1\|2211982_2212618_-\|holin	Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCB	NA	NA	NA	NA
VEE69246.1\|2212614_2213841_-\|holin	glycine betaine/carnitine/choline ABC transporter, ATP-binding protein, putative	Q6GZ03	Mycoplasma_phage	6.6e-20	50.5
VEE69247.1\|2214510_2215110_-	molecular chaperone GroEL	NA	NA	NA	NA
VEE69248.1\|2215289_2216927_+	Amino acid permease	NA	NA	NA	NA
VEE69249.1\|2217233_2218586_+	Carboxylesterase type B	A0A0B5J865	Pandoravirus	2.5e-12	34.2
VEE69250.1\|2218647_2219835_-	chloramphenicol resistance protein	NA	NA	NA	NA
VEE69251.1\|2220229_2221006_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
VEE69252.1\|2220998_2221661_-	ABC superfamily ATP binding cassette transporter, ABC protein	W8CYL7	Bacillus_phage	1.7e-17	34.5
VEE69253.1\|2222005_2223082_-	endoglucanase M	NA	NA	NA	NA
VEE69254.1\|2223437_2223704_-	addiction module toxin	NA	NA	NA	NA
VEE69255.1\|2223703_2223961_-	prevent-host-death family protein	NA	NA	NA	NA
VEE69256.1\|2224321_2224777_+	lipoprotein	NA	NA	NA	NA
VEE69257.1\|2224944_2226522_-	Ferredoxin-dependent glutamate synthase	NA	NA	NA	NA
VEE69258.1\|2226715_2227465_+	membrane protein	NA	NA	NA	NA
VEE69259.1\|2227688_2228882_-	Antibiotic resistance protein	NA	NA	NA	NA
VEE69260.1\|2228893_2229643_-	nickel transport ATP-binding protein	G3M9Y6	Bacillus_virus	8.1e-21	31.2
VEE69261.1\|2229635_2230451_-	Oligopeptide transporter putative ATPase domain protein	G9BWD6	Planktothrix_phage	3.6e-14	29.8
VEE69262.1\|2230447_2231317_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
VEE69263.1\|2231313_2232249_-	Oligopeptide transporter putative membrane permease domain protein	NA	NA	NA	NA
VEE69264.1\|2232261_2233860_-	Oligopeptide transporter putative substrate binding domain protein	NA	NA	NA	NA
VEE69265.1\|2234002_2235304_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEE69266.1\|2235296_2236115_-	nicotianamine synthase	NA	NA	NA	NA
VEE69267.1\|2236125_2236947_-	Putative Similar to diaminopimelate epimerase	NA	NA	NA	NA
VEE69268.1\|2237887_2238250_-	Uncharacterised protein	NA	NA	NA	NA
VEE69269.1\|2238513_2239332_-	short chain dehydrogenase	L7RG25	Acanthamoeba_polyphaga_moumouvirus	4.4e-12	26.8
VEE69270.1\|2239566_2241105_+	aminobenzoyl-glutamate transport protein	NA	NA	NA	NA
VEE69271.1\|2241216_2241639_-\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: LR134305.1|VEE68702.1|1661213_1661462_-|Phage-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LR134305.1|VEE68702.1|1661213_1661462_-|Phage-protein

1661213_1661462_-

82 aa aa

1599038-1675874

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
LR134305_7	Orphan	7.2\|2019568\|18\|LR134305\|CRT	2019568-2019585	18	1649430-1649447	2

1. spacer 7.2|2019568|18|LR134305|CRT matches to LR134305 position: 1649430-1649447, mismatch: 2

ctttttgaaattctctat	CRISPR spacer
ctttttgaagttctatat	Protospacer
*********.**** ***

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134305

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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