CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134327	Aggregatibacter aphrophilus strain NCTC5906 genome assembly, chromosome: 1	2 crisprs	WYL,cas2,cas1,cas4,cas7,cas8c,cas5,cas3,DEDDh,DinG	0	3	4	2

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134327_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134327_1

667186-667484

TypeI

Consensus_repeat	Method
GTTTCAACACACAGCCGCCCGAAAGCGGCTGCA	CRISPRCasFinder
GTTTCAACACACAGCCGCCCGAA	CRT
TGTTTCAACACACAGCCGCCCGAAAGCGGCTGCAT	PILER-CR

4 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of LR134327_1

>merge|LR134327|1|667186-667484|CRISPRCasFinder,CRT,PILER-CR
GTTTCAACACACAGCCGCCCAAAGGTGGCTGCCGTTCAATCGGTTTTGCTTGTCCGTGGCCTTTGCCGTTTCAACACACAGCCACCCGAAGGCGGCGGCTGGCGACGATGGGGAGAGTTCGGCCGCATAATGGGTGTTTCAACACACAGCCGCCCGAAAGCGGCTGCAAAAAATGGTGAATCTGAATTTTTGGGTTTTAAGTTTCAACACACAGCCGCCCGAAAGCGGCTGCATTATTGTTATGTACAGAAACACAAAAAATATCTGTTTCAACACACAGCCGCCCGAAAGCGGCTGCT

>LR134327|1|1|667186-667484|CRISPRCasFinder
GTTTCAACACACAGCCGCCCAAAGGTGGCTGCC	GTTCAATCGGTTTTGCTTGTCCGTGGCCTTTGCC
GTTTCAACACACAGCCACCCGAAGGCGGCGGCT	GGCGACGATGGGGAGAGTTCGGCCGCATAATGGGT
GTTTCAACACACAGCCGCCCGAAAGCGGCTGCA	AAAAATGGTGAATCTGAATTTTTGGGTTTTAA
GTTTCAACACACAGCCGCCCGAAAGCGGCTGCA	TTATTGTTATGTACAGAAACACAAAAAATATCT
GTTTCAACACACAGCCGCCCGAAAGCGGCTGCT

>LR134327|1|1|667186-667474|CRT
GTTTCAACACACAGCCGCCCAAA	GGTGGCTGCCGTTCAATCGGTTTTGCTTGTCCGTGGCCTTTGCC
GTTTCAACACACAGCCACCCGAA	GGCGGCGGCTGGCGACGATGGGGAGAGTTCGGCCGCATAATGGGT
GTTTCAACACACAGCCGCCCGAA	AGCGGCTGCAAAAAATGGTGAATCTGAATTTTTGGGTTTTAA
GTTTCAACACACAGCCGCCCGAA	AGCGGCTGCATTATTGTTATGTACAGAAACACAAAAAATATCT
GTTTCAACACACAGCCGCCCGAA

>LR134327|1|1|667320-667484|PILER-CR
TGTTTCAACACACAGCCGCCCGAAAGCGGCTGCAAAAAATGGT	GAATCTGAATTTTTGGGTTTTA
AGTTTCAACACACAGCCGCCCGAAAGCGGCTGCATTATTGTTA	TGTACAGAAACACAAAAAATATCTGTTTCAA
CACACAGCCGCCCGAAAGCGGCTGCT

Protein	Signature genes	Signature genes Name	Protein_function
LR134327.1\|VEF41892.1\|671681_673475_-\|CRISPR-associated-protein-Cas8c/Csd1,-subtype-I-C/DVULG	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|187887
LR134327.1\|VEF41884.1\|667971_668985_-\|CRISPR-associated-endonuclease-Cas1,-subtype-I-C/DVULG	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
LR134327.1\|VEF41865.1\|655111_655444_-\|Branched-chain-amino-acid-transport-protein-(AzlD)	unknown	unknown	gnl\|CDD\|224601
LR134327.1\|VEF41870.1\|656176_657109_-\|Cyn-operon-transcriptional-activator	unknown	unknown	gnl\|CDD\|176132
LR134327.1\|VEF41872.1\|657373_659647_+\|5-methyltetrahydropteroyltriglutamate---homocysteine-methyltransferase	unknown	unknown	gnl\|CDD\|235367
LR134327.1\|VEF41879.1\|664476_665268_+\|Uncharacterized-protein-conserved-in-bacteria	unknown	unknown	gnl\|CDD\|197313
LR134327.1\|VEF41888.1\|670074_670545_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
LR134327.1\|VEF41886.1\|669023_670040_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134327.1\|VEF41861.1\|649826_652193_+\|Outer-membrane-cobalamin-receptor-protein	unknown	unknown	gnl\|CDD\|369481
LR134327.1\|VEF41889.1\|670803_671670_-\|Uncharacterized-protein-predicted-to-be-involved-in-DNA-repair	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
LR134327.1\|VEF41877.1\|660693_664467_+\|Maltodextrin-phosphorylase	unknown	unknown	gnl\|CDD\|340853
LR134327.1\|VEF41868.1\|655440_656172_-\|azaleucine-resistance-protein-AzlC	unknown	unknown	gnl\|CDD\|129446
LR134327.1\|VEF41894.1\|673471_674149_-\|CRISPR-associated-protein-Cas5,-subtype-I-C/DVULG	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
LR134327.1\|VEF41863.1\|652252_655045_+\|protease3	unknown	unknown	gnl\|CDD\|223685
LR134327.1\|VEF41896.1\|674319_674736_-\|putative-methyltransferase	unknown	unknown	gnl\|CDD\|225100
LR134327.1\|VEF41898.1\|674816_675761_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379784
LR134327.1\|VEF41880.1\|665278_666943_+\|EIICBA-Glc	unknown	unknown	gnl\|CDD\|131058
LR134327.1\|VEF41900.1\|675757_676339_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|166263
LR134327.1\|VEF41875.1\|659780_660494_-\|Trehalose-operon-transcriptional-repressor	unknown	unknown	gnl\|CDD\|274116
LR134327.1\|VEF41882.1\|667674_667968_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856

Protein	Function_ID	Function_description	E-value
LR134327.1\|VEF41892.1\|671681_673475_-\|CRISPR-associated-protein-Cas8c/Csd1,-subtype-I-C/DVULG	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	0
LR134327.1\|VEF41884.1\|667971_668985_-\|CRISPR-associated-endonuclease-Cas1,-subtype-I-C/DVULG	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
LR134327.1\|VEF41865.1\|655111_655444_-\|Branched-chain-amino-acid-transport-protein-(AzlD)	gnl\|CDD\|224601	COG1687, AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism].	8.75502e-39
LR134327.1\|VEF41870.1\|656176_657109_-\|Cyn-operon-transcriptional-activator	gnl\|CDD\|176132	cd08441, PBP2_MetR, The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold. MetR, a member of the LysR family, is a positive regulator for the metA, metE, metF, and metH genes. The sulfur-containing amino acid methionine is the universal initiator of protein synthesis in all known organisms and its derivative S-adenosylmethionine (SAM) and autoinducer-2 (AI-2) are involved in various cellular processes. SAM plays a central role as methyl donor in methylation reactions, which are essential for the biosynthesis of phospholipids, proteins, DNA and RNA. The interspecies signaling molecule AI-2 is involved in cell-cell communication process (quorum sensing) and gene regulation in bacteria. Although methionine biosynthetic enzymes and metabolic pathways are well conserved in bacteria, the regulation of methionine biosynthesis involves various regulatory mechanisms. In Escherichia coli and Salmonella enterica serovar Typhimurium, MetJ and MetR regulate the expression of methionine biosynthetic genes. The MetJ repressor negatively regulates the E. coli met genes, except for metH. Several of these genes are also under the positive control of MetR with homocysteine as a co-inducer. In Bacillus subtilis, the met genes are controlled by S-box termination-antitermination system. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.04316e-107
LR134327.1\|VEF41872.1\|657373_659647_+\|5-methyltetrahydropteroyltriglutamate---homocysteine-methyltransferase	gnl\|CDD\|235367	PRK05222, PRK05222, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional.	0
LR134327.1\|VEF41879.1\|664476_665268_+\|Uncharacterized-protein-conserved-in-bacteria	gnl\|CDD\|197313	cd09079, RgfB-like, Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins. This family includes Streptococcus agalactiae RgfB (for regulator of fibrinogen binding) and related proteins. The function of RgfB is unknown. It is part of a putative two component signal transduction system designated rgfBDAC (the rgf locus was identified in a screen for mutants of Streptococcus agalactiae with altered binding to fibrinogen). RgfA,-C,and -D do not belong to this superfamily: rgfA encodes a putative response regulator, and rgfC, a putative histidine kinase. All four genes are co-transcribed, and may be involved in regulating expression of bacterial cell surface components. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	1.23481e-124
LR134327.1\|VEF41888.1\|670074_670545_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.33619e-26
LR134327.1\|VEF41861.1\|649826_652193_+\|Outer-membrane-cobalamin-receptor-protein	gnl\|CDD\|369481	pfam07715, Plug, TonB-dependent Receptor Plug Domain. The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.	9.2007e-09
LR134327.1\|VEF41889.1\|670803_671670_-\|Uncharacterized-protein-predicted-to-be-involved-in-DNA-repair	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.51885e-153
LR134327.1\|VEF41877.1\|660693_664467_+\|Maltodextrin-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
LR134327.1\|VEF41868.1\|655440_656172_-\|azaleucine-resistance-protein-AzlC	gnl\|CDD\|129446	TIGR00346, Uncharacterized_membrane_protein_HI_1738, 4-azaleucine resistance probable transporter AzlC. Overexpression of this gene results in resistance to a leucine analog, 4-azaleucine. The protein has 5 potential transmembrane motifs. It has been inferred, but not experimentally demonstrated, to be part of a branched-chain amino acid transport system. Commonly found in association with azlD. [Transport and binding proteins, Amino acids, peptides and amines].	5.2473e-97
LR134327.1\|VEF41894.1\|673471_674149_-\|CRISPR-associated-protein-Cas5,-subtype-I-C/DVULG	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	4.76835e-117
LR134327.1\|VEF41863.1\|652252_655045_+\|protease3	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.08517e-61
LR134327.1\|VEF41896.1\|674319_674736_-\|putative-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	8.61626e-18
LR134327.1\|VEF41898.1\|674816_675761_-\|Uncharacterised-protein	gnl\|CDD\|379784	pfam16162, DUF4868, Domain of unknown function (DUF4868). This family consists of uncharacterized proteins around 320 residues in length and is a phylogenetically broad range of bacteria associated with the human gut microbiome. A member of this family from Lactobacillus casei CRL 705 is part of the gene cluster involved in synthesis of bacteriocin toxin, but the specific function of this family is unknown.	2.54175e-47
LR134327.1\|VEF41880.1\|665278_666943_+\|EIICBA-Glc	gnl\|CDD\|131058	TIGR02003, PTS_system_glucose-specific_IIBC_component, PTS system, IIBC component. This model represents a family of fused B and C components of PTS enzyme II. This clade is a member of a larger family which contains enzyme II's specific for a variety of sugars including glucose (TIGR02002) and N-acetylglucosamine (TIGR01998). None of the members of this clade have been experimentally characterized. This clade includes sequences from Streptococcus and Enterococcus which also include a C-terminal A domain as well as Bacillus and Clostridium which do not. In nearly all cases, these species also contain an authentic glucose-specific PTS transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
LR134327.1\|VEF41900.1\|675757_676339_-\|Uncharacterised-protein	gnl\|CDD\|166263	PLN02622, PLN02622, iron superoxide dismutase.	0.00199025
LR134327.1\|VEF41875.1\|659780_660494_-\|Trehalose-operon-transcriptional-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	1.02334e-60
LR134327.1\|VEF41882.1\|667674_667968_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.82432e-30

>LR134327.1|VEF41880.1|665278_666943_+|EIICBA-Glc
MKKLLSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPLISDAEWLARVGNIIAQIGWGIIGNLHLLFALAIGGSWANERAGGAFAAGLAFILINLITGHFFGVKIEMLTDPNAHVGTILTGDIPVANYFVNILGQPALNMGVFVGIIAGFVGATTFNSYYNFRKLPEVLTFFNGKRFVPFVVIYRSVLVALILAVFWPVVQTGINHFGEWIANSQDSAPILAPFVYGTLERLLLPFGLHHMLTIPMNYTSLGGTYEFLTGMQQGKQVFGQDPLWLAWISDLINLKDAGNMTQYNELLSTVTPARFKVGQMIGSSGILMGITLAMYVNVDPDKKTIYKGIFLSSALAVFLTGVTEPIEYMFMFVALPLYLVYAAIQGCAFAMADIVNLRVHSFGNIEFLTRTPMAIKAGIGMDLINFIWVSGVFAVAAFLIANFMIKKLNLATAGRNGNYDAKGTDEAPAEEKKVANASAQVVQIVNLLGGRNNIAEVDACMTRLRITVHNPELVGDAAAWKQAGAMGFIVKGTGIQAIYGPKADVLKSDIQDLLSSGVEIPKM
>LR134327.1|VEF41879.1|664476_665268_+|Uncharacterized-protein-conserved-in-bacteria
MKLLTLNVHAWLEDNQAEKIDIIADTIVEKGYDIVALQEVNQLMSAPAISQALKQDNYGVVLLNKINQRATQKYSLFWSNSHIGYDKYDEGIAFLTRLPVYEVDAFYCSQHQRLDSILSRKILGLTVEYQGQLVDCYSCHINLPNCAGENQLDNIRNIVERSQSRNLKILMGDFNTDAISDPNAYQKIKSLGLLDTFEMAEQKDSGITVEKAIDGWKGHSEEKRLDYIFLNQTKRVLSSQVVFNGKNKPVVSDHFGLEVELTL
>LR134327.1|VEF41877.1|660693_664467_+|Maltodextrin-phosphorylase
MLTRSSGVLMHITSLPNAFGIGSFGQSAYDFVDFLVETKQTYWQILPLTTTSYGDSPYQSFSAIAGNTHLIDFALLTQMGLLQETDYASVNFGDDPTKVDYERIFYTRRPILEIAVKHFLADKKRQADFKNFEKNNRTWLEDYAEFMAIKEHFGNKALQEWEDKLVVARKPKTLAKYRTMLKEQIQYFKVTQYFFFQQWLALKNYANQRGIKIIGDMPIYVAEDSVEVWTMPELFQLDKECKPLFVAGVPADQFSATGQLWGNPLYDWPEHKKQGYAWWIHRIEESFKIYDVLRIDHFKGFSDYWQVDGKADIAKYGTWQPGPGYDLFKAVKAQLGDLPIIAENLGNIDEKAEKLLTDCGYPGMKILQFGFENVSGESLDSPHYCIPHCIAYTGTHDNDVINGWYADLSTKQQQYINAYTHRATDESVCQAMIRQLFATVSNTVIATMQDILDLPASSRMNLPSTIGGNWEWRMQESDLTKAKKDFLTQITMLYGRANKEQVMIKFSEFVQQTTNKKLEKLSDHAIYVQLLNYVKTLAANKEKNTAKRKVYYISAEFLIGKLLSNNLINLGVYQEIKDELAQASKSLSHIEDIEPEPSLGNGGLGRLASCFIDSMSTLGLNAEGVGLNYHCGLFKQVFKNNEQHAEPNNWIEKESWLIPTDIRYEVPFKDFTLTSKLDRIDILGYKKDTKNHLNLFDIESINHKLIKKGITFDKTKIKENLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHRIKFAEAVEIVRNMVGYTNHTILAEALEKWPLAYLEEVVPHLVKIIKKLNKLVQKEYPNPDVQIIDKQKRVHMAHMDIHFSNSVNGVATLHTEILKNSELKAFYEIYPEKFNNKTNGITFRRWLEFSNQELAAYIKQLIGDGYLHDATQLEKLLAFKDDKKVHQKLAEIKFWNKLALKTYLKENKGIELDENSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKAGKLPKRKITVIFGGKAAPAYVIAQDIIHLILCLSELINNDPDVNHYLNVHLVENYNVSVAEKLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGAKNIYTFGKDSESIIKLYETAGYVSKDYYKKDKHIKRAVDFILDSTLVKLGNKNRLKRLHDELLNKDWFMTLIDFDAYVTAKEQILADYEDQDSWNEKVIHNIAKAGFFSSDRTIAQYNTDIWHCED
>LR134327.1|VEF41875.1|659780_660494_-|Trehalose-operon-transcriptional-repressor
MSKYKAVYNDIKSKITDGILPPKQELPSESELMQEYGFSKDTIRKALSLLEMDGYIKKQQGRTSIVLEHNLSTPQQLSEIKTVGELNRPLTHQVKTTLTSLYIVQGEEELMQIFNVNDQIDFYRIGRVREIDGEAVEYEVSYFDRRIVPFINREIAEQSIYHYLESELGLKISYSQREIVFRYANEEEKSTMDLGEYNMVVNVTSTTYLADGRLFQYGSISYRPDKITFASTAKRHV
>LR134327.1|VEF41872.1|657373_659647_+|5-methyltetrahydropteroyltriglutamate---homocysteine-methyltransferase
MTIFHLAGFPRVGAKRELKFAQERYWRGEIAEADLLDIAKKLREINWQHQANANADFVAVADFTFYDHILDLQVATGAIPTRFGFDSQNLTLDQYFQLARGNKTQFAIEMTKWFDTNYHYLVPEFHKDTQFKANPAHYVQQIREAKALGHNVKPTIVGPLTFLWLGKEKGAAFNRFDLLNKLVPVYVDILNALSSEGVEYIQIDEPALTLDLPAEWVAAYKEVYATFAAQVNAKLLLATYFGSVSEHADLLKALPIAGLHIDLVRAPEQLSAFADYDKILSVGVIDGRNIWRANLNQVLDVVEPLKAKLGERLWIAPSCSLLHTPYDLAVEIQLQANKPELYQWLAFTLQKIQELRVIKTALEQGREAVQAELDASQAAADARKNSREIHRTCVAERLANLPKNAVQRKSPFAERIKLQNAWLNLPLLPTTNIGSFPQTTEIRHARAAFKKGDLSLADYEAAMKKEIEFVVREQEKLDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVTRPEPMTVRWSQYAQSLTNKVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIAVALSDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSSMGCKDDTQIHTHMCYSEFNDILPAIAALDADVITIETSRSDMELLTAFGDFKYPNDIGPGVYDIHSPRVPTAEEIEHLLRKALQVVPKERLWVNPDCGLKTRGWPETIAALKVMVDITKKLRAELA
>LR134327.1|VEF41870.1|656176_657109_-|Cyn-operon-transcriptional-activator
MKPIFLELRHLKTLLALKETGSVSLAAKRVYLTQSALSHQIKLLEDQYGLPLFERKTQPLHFTPAGERLIQLANDILPKVIEAERDLARVKQGEAGELRIAVECHTCFDWLMPAMDLFRQHWPLVELDIVSGFHTDAVGLLLSHRADWAVVQEVEETPDIVYKPLFSYEMVGLCAKDHPLAAKDVWQAEDFIDQTLITYPVPDDMLDLLRKVLHPKGVNPTRRTSELTIAIIQLVASKRGVAALPFWAAKPYLDRGYIVARKITEQGLHSNLYAATRELDSQIAFVDDFYETVKAQSFSTLPELSILEEI
>LR134327.1|VEF41868.1|655440_656172_-|azaleucine-resistance-protein-AzlC
MSDVKTNSHPIWAAAKAALPYSAPMLAGFLFLGVAYGIYMKALGFSFWYPVLMALLIYGGSVEFIIAGALSLAFAPLNALLITLMVSGRQLFYSISMLEKYGKSLGKKRPYLIATLVDESFSLNYMAKVPSHIDRGWYMFFVSFYLHMYWMIGAGLGNLFGNIIPFDLKGIEFAMTALFLVIFAENWAQEKSHESSLLGLAIAAISLIVFGREYFLLPTLIGIWTVLTFRRPKLSSRLERIEE
>LR134327.1|VEF41865.1|655111_655444_-|Branched-chain-amino-acid-transport-protein-(AzlD)
MTLTEQIITIGIAVLGVQFTRWLPFWVFPANRPIPEYIRYLGKVLPAAMFGMLVVYCYKNVDVFSGFHGVPEFLSGVIVVALHLWKRNMFLSIAAGTMLYMFLVQRVLVA
>LR134327.1|VEF41863.1|652252_655045_+|protease3
MSNQKTMKKLTALFVLLCSFRLVIACQAGIDPDALAFDPNIKHGKLTNGLQYYILNNRDPKDRVYIRLVVNAGSMHEDDDQKGIAHLVEHMAFNGSKKYPENTIINALEKLGMKFARDINAFTDFENTVYTLNLDGNSPQKLSLAFDVINEWMNHLTILPKDLDGERGVVQEEWRRRLSPMLRLGDKKSAIEMAGSRYVLRDPIGDMNIIRHISRDRVADFYHKWYRPDNMSLIVVGDIDTHKITQLISQQLDKPSSHTQRPLDKIDFSIPLIHHWRVASIAEQGTNIPALELSFFEEDKQKETITDYKQDLIQQIVTRLVNLRLQKWEENQNNWLDSANFYRSHLGKQTLQSVFSLQLADTNYLKNITALFAFIAEIKQHGFTADELNSEIARLHNLNEKQQNIRPGSLKIANDLIAIAANHQIMLSAKERYNLNRRFLNEIKVTDLNVTFNQMLALNAKLLLITQLLPEKKLPFDATYIEQRWNQAMRSDQNQWENKKHIVKQPHFEFKDGSLVLEKHWDKGNIDEFRLSNGAKLIYHYSNKTPNQVHFRAVTSGGLRSVPNQDYHLLRTAITLVDDTGTGELTQADVSNLFGQSPLVLATVIDDDKQGFTGVAKPQDLSRLLTLFRLKLQSAPVSNNVLQKYHRETQDYFKQIDAETKFMQAISYLRRPNTATVYTQNQNEQLSFTAAQLSQIYQEKILGKTDFTYFIIGDISRSELEKLAKQYLATVEIKTQARAYQPGYIHTPKKAFIMRGLSEPRADVEIYLTAENQWHPEQKYALEILGEIVQEKLRLVLREKVSGIYSVNSWFSQDPHTPQIEGKIAFSCAPNRAEELIKLTHQILDEIIENGIDETLLRKKQAEQQQYIKRQFDSLVSVAGMIEDSYWQQGNPQSVYLYQRLEQLADKPHLEALARKVLVKAARFEAILRQ
>LR134327.1|VEF41861.1|649826_652193_+|Outer-membrane-cobalamin-receptor-protein
MYKKTKIAFFICTALYAQHVLSEEKSTNKSNMLPEIIVYGDSNKSLSSTQAVTSNEMEKIPTTNNNITDYLRSNPHIRYEDSDQNGFQLGEIKPQNISINGADANQTAYFVDNVNVNNDLTVDNEIFDGAMQVVPGISNTQAYFFDASMLSKVEVHDSNISASLGGFMGGAVVAKTKQYNGKDGVSLKYRTTNSGWAKINADSSAKTLLDKIRPDAGGVAEFQPKYHKQTFSIMAEKGLTENLGMVIGYSKRHARIQQNRLIGYAPDVKLDKQNHKRDSDNLLLNFNLAASEKDRFELGFRYSNYKEQKYYATNIDSNVSDYHQALGSTLAWVHSFNSGILTNTLAYDHFKDKRKSSSANVEIVSVFDENFDPLYDYEKGGYGNSSLTQDNIHFSTEFAVDPFNLGFANHSISIGGIYQATHYKFNRPQDVHSKIIQKYPNLSPIETTNVTHQGNAQTRYQNFVFYTEDLIKWKKLELRPGVRIERDDYLQNNNIAPRFVARYKPWEETGFTLGLNRYYGRSFASLKLTNEILKINRDTSRKYQEFHSLKTPYADELSIGFDQEFNNLAFKLNYIHRKNKNRIVLKRDANKVNFYHNGSDFSVEVYTFQMNNIEPWQLGKSYWTSSLGFDWLKTKRADIGRDLDPNELVYLDGKLLTRREMLNKVNSSTEDWITRFGLDMAIPDYNITWSNKVYIKAPIRSYDVLEGDFNDGISRYRSYHYGRHTQWDSSIRWQPTITGNHSIYLQVDILNVLNKTRKSKTVKPISSNDEYGIYTPGREFWLEVGYKF
>LR134327.1|VEF41882.1|667674_667968_-|CRISPR-associated-endoribonuclease-Cas2
MLMLITYDISFDDPNGQARLRRIAKHCLDYGVRAQYSVFECDVTPDQWVMLKNKLLETYDPTCDSLRFYHLGSKWRNKVEHHGAKPAVDVFKDVLVI
>LR134327.1|VEF41884.1|667971_668985_-|CRISPR-associated-endonuclease-Cas1,-subtype-I-C/DVULG
MRKLQNTLYITTQGSYLHKERETLVVEQERKKVAQLPVHSIGHIFCFGNVLVSPFLLGFCGENNVNLAFFTENGRFLGRLQGRQSGNVLLRRAQYRVSEQNPVSIARNIIAAKIQASKRVLQRQIRNYGENAAIQSAVDSLNISLRQLKGTAELDVVRGIEGDAAARYFGVFGQLLSEKSGFSFDGRNRRPPRDGVNALLSFVYSILGKDISGALQGVGLDPQVGFLHADRPGRDSLAQDILEEFRAWWADRLVLSLINRGQIKPQDFVAEASSAVSLKADARKLLFQALQAKKQEKIVHPFLGEEVEIGLLPYIQAMLLARHLRGDLAEYPPFLMR
>LR134327.1|VEF41886.1|669023_670040_-|Uncharacterised-protein
MNIRPDFLPLPWQLNSLLECAKVLENNKNDWSHLKNKEDFSQVYYLDLKDRLPLEKIYATGAMVSGMSDDLRQFNYPNYYPTLTSFLQSSVINNIITGKWSDDLTSILKNAEDKVYELKENSVSVPWAIEQMLKLFKKQIELLNIIRQFLIGLKQSNIYQRENEILIGSVSVERILECINRAGKRFEDLPATYNQFGEEDLRDNILLALSGISDISAYGEVFNKVGKTDILAFENGEKKFIAECKFWRGEKVFLGAINQLLSYLTWRDNNVAVIIFVDNVDFVRVIDIARSSIQQHPYYVSLISQRDESWFEYKFNNGNQDINLSLMIYHIPSSIQHS
>LR134327.1|VEF41888.1|670074_670545_-|CRISPR-associated-protein-Cas4
MSGWIRASRKRARVCALSGRCKLGISGVLDLVEVDTKTGRLKPVEYKRGKPKPDPMDEIQLCAQGLCLEEMTVQTVSEGALWYMQTRHRVPVVFSDDLRAQTLSTIAAVRELLNSGQTPPPDYGKRCKACSLVEICQPELLGKRDRSLGYVVGLFE
>LR134327.1|VEF41889.1|670803_671670_-|Uncharacterized-protein-predicted-to-be-involved-in-DNA-repair
MSAIQNRYEFVYFFDVTNGNPNGDPDAGNMPRLDPESSKGLVTDVCLKRKIRNFVEISSENEAGYEIYVKEKSVLNLQNKRAYEALGIESEAKKLPKDEAKARDITAWMCKNFFDIRTFGAVMTTEVNSGQVRGPVQLAFAQSIDPIVPLEVSITRMAVTNEKDLEKERTMGRKYIVPYALYRVHGFISANLAAKTGFSDDDLAKLWQALQLMFEHDRSAARGEMAARKLIVFKHDSALGNQPAHKLFDAVKVERVNGESGTPASGFDDYKISVVSDGLNGVSVEELL
>LR134327.1|VEF41892.1|671681_673475_-|CRISPR-associated-protein-Cas8c/Csd1,-subtype-I-C/DVULG
MILASLARYYRRLAAENDEMGNPKVPPYGFSEEKIGWILVLDKEGRLKTVVPNLTADKKPQPKLMSVPQSFKRPGTTPKPFFLWDKTSYSLGVETNKNKAEAKEKPFTSSEKTFDAFKQYHLDLLQNSEDEGLQALCRFLQNWQPAYFAAENLPAEMLDANIAFSLEKPTALIHKREAAQTLWAGCLKSDEALEGLCLISGDTAPIARLHPAIKGVFGGQSSGGSIISFNKEAFASFGKEQGANAPVSEQSAFAYTTALNYLLRQRNQEENNHCLTIGDASTVFWAEADDNATAQAAEGFFAHVFTPPDDEQESAKVFNVLEQIGKGRPLQEIAPELSANTRFYILGLAPNAARISVRFWLDTTFGQLAENLAQHWQDLALEPCAWKTPPSIWRLLLQTAVLGKSENISPVLAGEMTRAVICGTPYPMSLLSQLITRIRADGDVNGLRVAMMKAVLERRFRKGFIEEGVPMSLNNESPNRAYLLGRLFAVLERIQYQALGDLNAGIADRYYGSASAVPFSVFPRLLSGAKHHLSRLRKDKAGMAVNLDKDLGEIIAKLPETFPRHLSIDEQGRFAIGYYHQEQSYFAKKETAETIEN
>LR134327.1|VEF41894.1|673471_674149_-|CRISPR-associated-protein-Cas5,-subtype-I-C/DVULG
MANQIRLHIWGDYACFTRPEMKVERVSYDVITPSAARGILAAVHWKPAIRWVIDRIYVLKPIRFESVRRNELGGKISAGKVSGAMKRKSVADLYTLIEDDRQQRAATVLKDVAYVIEAHAVLTAKAGADETVTKHIEMFKRRAKKGQCFQQPCLGVREFPADFALIDEGEPLPPLALSEREANRDLGWMLHDIDFDHGSTPHFFRAQMKDGVIDVPPFYAEEVKA
>LR134327.1|VEF41896.1|674319_674736_-|putative-methyltransferase
MLEDTEKSYHAKVWSESAVFDNRLIFGDNLLSLKALEQEFTGKVKCVFIEPPFNTGSAFEHYDDGVEHSIWMGLMRDRLEIIKRLLSDDGSLWITIDDNEAHYLKVLCDEVFGRRNFVVNAIWVKKSAPQNDAKLIMY
>LR134327.1|VEF41898.1|674816_675761_-|Uncharacterised-protein
MSTNTKKQIKEIQAENFNDWSVSFWLIKRKAPTTIKEASYHAWRVDMDKKLPTRFKGYLKNQLQGKKFHVEKYDYSNADCDDVLLTVDSGITDFEKVEAEINKGFDNPRVDNHKDLLNSWAYVILFEKDDKKLYAWKKINTDTQPKKVASKGILFFINKELVDPDDKEVFVIYPNYDFFVYKRTVFIASKKQFESSMNFREGMKRKSAEVIADFKNLETFKNIELIEQYVGNNLHHLRKMASILKSGYYKQPDYLKKLIAVNKKEKWDLKVENGQIVVEEETIDLLLKLLNNDRLRSPINDEIFDAAAKSKVNK
>LR134327.1|VEF41900.1|675757_676339_-|Uncharacterised-protein
MADSSLRLRPWVSLILFISAYSPLMVIMAIKQIDLTSPNYFNSPEIGIGLLVAAIISSIIVLQVVKSVRSGLMVVVSKASNKSGDMFGYTIPYMMSFMRIDLTDWQTILAIILFLTVLFTMAYRTKTVFINPILAIFGYMLIDCTFKRGEKEVQAMVITKQPISYGDTVCLDRLSHYLYIRSNSDYKNDKEKS

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Crispr_ID: LR134327_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134327_2

1433507-1433648

Orphan

Consensus_repeat	Method
TGGAGCGGGAAACGAGGCTCGAACTCGCGACCCCAACCTTGGCAAGGT	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of LR134327_2

>merge|LR134327|2|1433507-1433648|CRISPRCasFinder
TGGAGCGGGAAACGAGGCTCGAACTCGCGACCCCAACCTTGGCAAGGTTGTGCTCTACCAACTGAGCTATTCCCGCATGGCTTGATGTTGAGAATGGAGCGGGAAACGAGGCTCGAACTCGCGACCCCGACCTTGGCAAGGT

>LR134327|2|2|1433507-1433648|CRISPRCasFinder
TGGAGCGGGAAACGAGGCTCGAACTCGCGACCCCAACCTTGGCAAGGT	TGTGCTCTACCAACTGAGCTATTCCCGCATGGCTTGATGTTGAGAA
TGGAGCGGGAAACGAGGCTCGAACTCGCGACCCCGACCTTGGCAAGGT

Protein	Signature genes	Signature genes Name	Protein_function
LR134327.1\|VEF43340.1\|1428881_1429358_-\|ADP-binding-protein	unknown	unknown	gnl\|CDD\|182615
LR134327.1\|VEF43332.1\|1424571_1425528_-\|tRNA-dimethylallyltransferase	unknown	unknown	gnl\|CDD\|234626
LR134327.1\|VEF43350.1\|1435680_1435938_+\|Phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|182777
LR134327.1\|VEF43346.1\|1431668_1433294_-\|Putative-phosphoethanolamine-transferase-ybiP	unknown	unknown	gnl\|CDD\|293741
LR134327.1\|VEF43349.1\|1434412_1435453_+\|Putative-ribosome-biogenesis-GTPase-RsgA	unknown	unknown	gnl\|CDD\|237039
LR134327.1\|VEF43357.1\|1441078_1442647_+\|Periplasmic-oligopeptide-binding-protein-precursor	unknown	unknown	gnl\|CDD\|173869
LR134327.1\|VEF43330.1\|1424142_1424445_-\|RNA-binding-protein-Hfq	unknown	unknown	gnl\|CDD\|179001
LR134327.1\|VEF43338.1\|1427377_1428835_-\|N-acetylmuramoyl-L-alanine-amidase-AmiB-precursor	unknown	unknown	gnl\|CDD\|236692
LR134327.1\|VEF43359.1\|1442685_1443483_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134327.1\|VEF43348.1\|1433795_1434341_-\|Oligoribonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235429
LR134327.1\|VEF43344.1\|1431025_1431643_-\|spermidine-synthase	unknown	unknown	gnl\|CDD\|235139
LR134327.1\|VEF43326.1\|1421789_1422749_+\|Transcriptional-regulatory-protein-tyrR	unknown	unknown	gnl\|CDD\|225821
LR134327.1\|VEF43352.1\|1437866_1438367_+\|Glucose-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|181859
LR134327.1\|VEF43355.1\|1440674_1441040_+\|Inner-membrane-protein-ybaN	unknown	unknown	gnl\|CDD\|377291
LR134327.1\|VEF43353.1\|1438502_1440542_-\|Oligopeptidase-A	unknown	unknown	gnl\|CDD\|182832
LR134327.1\|VEF43328.1\|1422745_1424128_-\|GTP-binding-protein-HflX	unknown	unknown	gnl\|CDD\|182934
LR134327.1\|VEF43334.1\|1425530_1427378_-\|DNA-mismatch-repair-protein-mutL	unknown	unknown	gnl\|CDD\|234630
LR134327.1\|VEF43342.1\|1429527_1431039_-\|Spermidine-synthase	unknown	unknown	gnl\|CDD\|223498
LR134327.1\|VEF43351.1\|1436078_1437806_+\|Phosphoenolpyruvate-protein-phosphotransferase	unknown	unknown	gnl\|CDD\|183017
LR134327.1\|VEF43361.1\|1444598_1445252_-\|GTP-cyclohydrolase-2	unknown	unknown	gnl\|CDD\|234745

Protein	Function_ID	Function_description	E-value
LR134327.1\|VEF43340.1\|1428881_1429358_-\|ADP-binding-protein	gnl\|CDD\|182615	PRK10646, PRK10646, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE.	2.97302e-64
LR134327.1\|VEF43332.1\|1424571_1425528_-\|tRNA-dimethylallyltransferase	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	3.58651e-165
LR134327.1\|VEF43350.1\|1435680_1435938_+\|Phosphocarrier-protein-HPr	gnl\|CDD\|182777	PRK10850, PRK10850, phosphocarrier protein Hpr.	6.74062e-37
LR134327.1\|VEF43346.1\|1431668_1433294_-\|Putative-phosphoethanolamine-transferase-ybiP	gnl\|CDD\|293741	cd16017, LptA, Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase. Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase catalyzes the modification of the lipid A headgroups by phosphoethanolamine (PEA) or 4-amino-arabinose residues. Lipopolysaccharides, also called endotoxins, protect bacterial pathogens from antimicrobial peptides and have roles in virulence. The PEA modified lipid A increases resistance to the cationic cyclic polypeptide antibiotic, polymyxin. Lipid A PEA transferases usually consist of a transmembrane domain anchoring the enzyme to the periplasmic face of the cytoplasmic membrane.	1.54082e-76
LR134327.1\|VEF43349.1\|1434412_1435453_+\|Putative-ribosome-biogenesis-GTPase-RsgA	gnl\|CDD\|237039	PRK12288, PRK12288, small ribosomal subunit biogenesis GTPase RsgA.	0
LR134327.1\|VEF43357.1\|1441078_1442647_+\|Periplasmic-oligopeptide-binding-protein-precursor	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	8.54393e-139
LR134327.1\|VEF43330.1\|1424142_1424445_-\|RNA-binding-protein-Hfq	gnl\|CDD\|179001	PRK00395, hfq, RNA-binding protein Hfq; Provisional.	3.41317e-43
LR134327.1\|VEF43338.1\|1427377_1428835_-\|N-acetylmuramoyl-L-alanine-amidase-AmiB-precursor	gnl\|CDD\|236692	PRK10431, PRK10431, N-acetylmuramoyl-l-alanine amidase II; Provisional.	2.63263e-106
LR134327.1\|VEF43348.1\|1433795_1434341_-\|Oligoribonuclease	gnl\|CDD\|235429	PRK05359, PRK05359, oligoribonuclease; Provisional.	3.29982e-134
LR134327.1\|VEF43344.1\|1431025_1431643_-\|spermidine-synthase	gnl\|CDD\|235139	PRK03612, PRK03612, polyamine aminopropyltransferase.	2.59894e-09
LR134327.1\|VEF43326.1\|1421789_1422749_+\|Transcriptional-regulatory-protein-tyrR	gnl\|CDD\|225821	COG3283, TyrR, Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism].	4.53214e-158
LR134327.1\|VEF43352.1\|1437866_1438367_+\|Glucose-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|181859	PRK09439, PRK09439, PTS system glucose-specific transporter subunit; Provisional.	1.474e-103
LR134327.1\|VEF43355.1\|1440674_1441040_+\|Inner-membrane-protein-ybaN	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	3.66935e-40
LR134327.1\|VEF43353.1\|1438502_1440542_-\|Oligopeptidase-A	gnl\|CDD\|182832	PRK10911, PRK10911, oligopeptidase A; Provisional.	0
LR134327.1\|VEF43328.1\|1422745_1424128_-\|GTP-binding-protein-HflX	gnl\|CDD\|182934	PRK11058, PRK11058, GTPase HflX; Provisional.	0
LR134327.1\|VEF43334.1\|1425530_1427378_-\|DNA-mismatch-repair-protein-mutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
LR134327.1\|VEF43342.1\|1429527_1431039_-\|Spermidine-synthase	gnl\|CDD\|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	1.89411e-29
LR134327.1\|VEF43351.1\|1436078_1437806_+\|Phosphoenolpyruvate-protein-phosphotransferase	gnl\|CDD\|183017	PRK11177, PRK11177, phosphoenolpyruvate-protein phosphotransferase PtsI.	0
LR134327.1\|VEF43361.1\|1444598_1445252_-\|GTP-cyclohydrolase-2	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	2.81711e-134

>LR134327.1|VEF43346.1|1431668_1433294_-|Putative-phosphoethanolamine-transferase-ybiP
MFKKFLSYLNSRIFWIWLLFFSFITLIISPENSAYYGIFVIYIIYYLIFSFNQKIFWLFITFVVITLSLYQPIYSSYGNLNSGVVAAFFETNPAESFEFLGKLKIDQFILPFLFSLSAYILYRLREQATPQGEITEKDIKYKKILNITLIIVTIFSIIWIPTKFHFENSSKEQIDSHWTLANSPVNLISFYANIIDSITDYYNDKKDLEAAKDILPPWHIISTQPKYKNYILIIGESARKDYMSSYGFKLPTTPFLDKTNGYINAGYVSAAPATYHSLLNTLHFKPKDKGKKDYSYNIISLAKAAGIKTFWLSNQGTIGKYDTLASRLGIGADFHYFTKKGGFITNNADDFKLLEELKIKFKEKAYENDTRLFVIHLMGSHRNFCQRITDKEKKLEFINESLSCYVNTILKTDKLIEEIVNVLKEQNEPYSLIYFSDHGLSHVNKENKKEVDLDFGEEHKQNFEVPFVKISSDDTSREVVNVKRSAFNFIYGFSQWLGIETKELDQEYNFFSNKNDENIKVFNFKENIPYNTLKNDDIPNL
>LR134327.1|VEF43344.1|1431025_1431643_-|spermidine-synthase
MNKYGTKTVKTVFFMSGFAALIYQIAWQRMLFTAFGVDLESITIIIAVFMAGLGIGAYFGGRIADKFPKHIILLFALTEIGIGIFGFASPTLIELTKNLFLHSSIITIAFSNFVLLLFPTFLMGSTLPLLTQYLNQHFDNIGNNIGWLYFTNTLGAAFACITTGFFLFNYLTIIQVIYLAAIINCLVATIIFLKYRKRGMNYDNH
>LR134327.1|VEF43342.1|1429527_1431039_-|Spermidine-synthase
MTITRKAMLLSFLSGFLSLGLEVIWIRLFSFYGIILPQIFSLTLALFLLGIACGSLIGKNLCQSGKGNISYIGYAFILSAFFDCLAITMIMYFPLEGMLGIFIVSIFFCALVRGIVFPIVHHLGAEQKKTGAAISNVYFANVLGCTISPILIGFYLLDTFTTQQTYLIIILITLITATFCVPTKWLKSAVSIFAVLVMMTTFILPEKVIHALAQKKDENGQDLKLEKLIENKHGFIQVYLNSNNDELVFGSNVYDGMLNTNLNHSHNGIERAYLLPIIAPHAKNILVVGLSTASWTKVLTSMPELESMTVIELNPGYPQLAGMYPEMHKFLQDKRVNLITDDGRRWLNKNPDRKFDFILMNTTFHWRNYATNLLSKEFLELTKSHLNPNGFIYFNTTSSFDAYYTSKDVFPHVYSYVNMSLASLSPIPEITKEQVLQGLEKLKWEDGNRVFDSSEALNKGVNNILNRPFISYKNIDFSKLRRNAEVITDNNMITEYKYGFFNQ
>LR134327.1|VEF43340.1|1428881_1429358_-|ADP-binding-protein
MTERFTQYIPNENAMCAFGEKLIKAICQMSNNKSVMLYLNGDLGAGKTTLSRGMIQGLGHSGNVKSPTYTLVEEYKIGGKIIYHFDLYRLADPEELEFMGIRDYFAENTICLIEWAEKGAGLLASADLLVNIAYAENARNIELLAESETGRQIIQQLN
>LR134327.1|VEF43338.1|1427377_1428835_-|N-acetylmuramoyl-L-alanine-amidase-AmiB-precursor
MHGLLFFAVLAFADNTWTIAIDPGHGGKDPGAIGRNLKIYEKNVTLSIAKELKALLDKDPHFRAVLTRNGDYYISVPQRSEIARKYKANYLVSIHADSSETPNLRGASVWVLSNRRANDEMGQWLEDHEKRSELLGGAGSVLASHNEKYLDQTVLDLQFGHSQRVGYELGNIVLRHFSQIASLSRPTPRHASLGVLRSPDIPSILVETGFLSNQEEELKLSTPAYRKRIAKAIYNGLAEYRRKNVKDEPKVAIVDKNEKTSEKSTALEVKDSGIRHTVKSGEGLGKLAEKYHVSTADIIALNKLKRKALWVGETIKIPDNGKNIPTTEDKSVKTKENNIVEVKDSGVRHKVKRGETLGKLAEKYKVSANDILTLNKLKRKELLIGENLKIPAIAKAETSNKTEKGKETETPKPVDKSPKTQGKTKPEVKEAVPKFHTVKKNETLYSIAREYKIAPNKLLKLNPQLKNGKVLSGQKIKLTEDQGKK
>LR134327.1|VEF43334.1|1425530_1427378_-|DNA-mismatch-repair-protein-mutL
MTIRVLSPQLANQIAAGEVVERPASVVKELVENSLDAGADKIQIDIENGGAGLIRIRDNGIGIAKEELALALARHATSKIADLADLEAILSLGFRGEALASISSVSRLTLTSRTAEQHEAWQVYAQGRDMETTIQPASHPIGTTVEVANLFFNTPARRKFLRSEKTEFSHIDEVIRRIALAKFNISFTLTHNGKVLRQYKSAVTNEQKLKRVAAICGDDFIQNALQIDWKHDDLHLSGWIALPHFNRPQNDLNYCYVNGRMVRDKIITHAIRQAYAEYLSNDQYPAFVLFIDLNPNDVDVNVHPTKHEVRFHQSRLVHDFITQGISHALTSESLDFSATETERKIQEPMGLWEVSSKPNRSAAGPNMFTQPSTYSTGYCVEKQPSEGAYHSSQKHRQNPPHFNSDNITPSVLDAHKYLWMDSTAPSRSKITISEDSKPRSTCLHALALVGNHALLLQQERHFYLLSLSRLQRLKLELNLTLTATSQPLLIPVIFRLSETQWQAWQQQKAWFTQVGFDFLAEDAQRKITLQKVSAHLRRQNLQQLIIALLNEPVENLSEFLTALLAQLDFPPIQVLADAVTMLTEIEQLLNKQSHIQLSDLFLEINWQPYLTQLAD
>LR134327.1|VEF43332.1|1424571_1425528_-|tRNA-dimethylallyltransferase
MMQHSEHKPPAIFLMGPTASGKTDLAIQLRQQLPVEVISVDSALIYRGMDIGTAKPTAEELALAPHRLIDICDPAESYSAMNFCHDALREMQDITAQGKIPLLVGGTMLYYKALLEGLSPLPSADEKVRSEIETKAMQIGWSGLHQELAKIDPISAQRINPNDSQRINRALEVFYLTGKTLTELTAQKGEALPYDILQFAIAPEQREVLHLRIEQRFHKMIELGFQQEVEKLYQRSDLKENLPSIRSVGYRQMWEYLRGDYDHKEMIFRGICATRQLAKRQITWLRGWKSPIQWLDSLHPTQALEKVLVSVNSLSDKQ
>LR134327.1|VEF43330.1|1424142_1424445_-|RNA-binding-protein-Hfq
MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVAHHNANQQQQHQQGQQQEAPSSVETNTDAQTE
>LR134327.1|VEF43328.1|1422745_1424128_-|GTP-binding-protein-HflX
MDNLLGNLTQSAVDSGNVSTAFSMPENSTQTSDHTINNAIIVHCFFEQSKNTDDLTEFQLLAKSANVHILNVITATRSTPQAKYFVGSGKAEEIADAVRQYNAALILANHGLPPAQARNLETLCDCRVVDRNGLILDILAQRARSHEGKLQVELAQLKHLSTRLVRRKTGLDQQKGAVGLRGPGETQLETDRRLIKVRINQLQSRLEKVAKQRNQNRQTRQKADIPTISLVGYTNAGKSTLFNLITDANVYAADQLFATLDPTLRRLTLQDVGTTILADTVGFLRDLPHDLISAFKSTLQETTEASLLLHVIDCADNRKLENIEAVNQVLEEIGAQEVPRLLVYNKIDQLENVTPYIEYDEKHLPSAVYISANSGSGLDLLLEAIHLRLTEHILNLQIRLPPSDGKLRHAFYQLNCVEKEEINEQGEFLLSIRLEKTEWLKLVKRFTQLTPFNPIQPDEN
>LR134327.1|VEF43326.1|1421789_1422749_+|Transcriptional-regulatory-protein-tyrR
MTTLKNTDPFAQIVSKNPRMQDMIEKAKKFALLNVPLLIQGETGTGKDVIAKACHDFSERRDHAFLAVNCAGIPGEDAETEMFGRRNKDGEFIGFFEYADGGTVLLDGVEELPLTLQAKLLRFLSDGTFRRVGEEEERYANVRVICTSQQPLQHYVEQGKMRSDLFHRLNVLSLNLPLLRERKEDLALLSYQLIQEISEKLGVFPPHFDENVLRYLQEYPWPGNIRELYNALYRACSLCQNNQLRIEDLGLAPQIPHSQDIDQFITEGDTLDEMVGRFEAAVLNKFYAKYPSSRKLATRLGVSHTAIANKLRQYGIGKS
>LR134327.1|VEF43348.1|1433795_1434341_-|Oligoribonuclease
MELDKQNLIWIDLEMTGLDPEKERIIEIATIVTDKNLNILAEGPVLAVHQPDELLNKMSEWCVKTHTANGLVERVKASKLNERAAELQTLDFLKKYVPKGTSPICGNSVAQDKRFLFKYMPELADYFHYRHLDVSTLKELAARWKPEILNGFTKQNTHLALDDIRESIKELAYYREHFLNI
>LR134327.1|VEF43349.1|1434412_1435453_+|Putative-ribosome-biogenesis-GTPase-RsgA
MSKPKLTQNQKRRIQSNNNKVLHRHQKKEIEWRDDMLGESQEGVVVTRYARHADVENAQGEIFRCNLRRTLSGVVVGDHVIWRQGNEQLQGVSGVIEGIHPRKNEISRPDYYDGIKVIAANIDRIIIISSVLPSLSLNIIDRYLVVCEEANIEPIIVLNKVDMLTEAQWLEADELLAIYRKIGYQTLMLSAQSGKNLEKLTALLSHGVSIFVGQSGVGKSSLINAVLPHVDAQVGEVSATSGLGQHTTTSSCLYHLPQGGSLIDSPGIREFGLWHLEEEQITKGYREFQTVLGTCKFRDCKHLSDPGCALRQAVEEGKISTVRYENYHRLLASRKEMKSQRHFSSE
>LR134327.1|VEF43350.1|1435680_1435938_+|Phosphocarrier-protein-HPr
MYSKDVEITAPNGLHTRPAAQFVKEAKAFASDITVSSAGKSASAKSLFKLQTLALTQGTVITISAEGEDAEKAVEHLVALIPTLE
>LR134327.1|VEF43351.1|1436078_1437806_+|Phosphoenolpyruvate-protein-phosphotransferase
MISGIPASPGIVFGKALVLKEEKIVLDTQKIKDSQIENEIARFYAGRDAAVEQLTSIKDRAYQSLGEEKAAIFEGHLMILEDEELEEEIIDYLRSNHVNAAVAANVVIDQQVAMLSEIDDEYLKERAGDIRDIGNRLIKNILGMHIVDLGEINEEAILVAYDLTPSETAQLNLDKVLGFVTDIGGRTSHTSIMARSLELPAIVGTNNVTEKVKTGDFLILDALNNAVYVNPSQQEIQRLKTLQDKLAEEKAELAKLKDLPALTLDGHQVDVVANIGTIRDVEGAERNGAEGVGLYRTEFLFMDRDQLPSEEEQFIAYKEVVEAMNGNLVVLRTMDIGGDKELPYLNLPKEMNPFLGWRAIRIALDRREILNAQLRAVLRASAYGRLAVMFPMIISVEEIRELKSVIEELKVELRNEGKAFDEDIQVGVMVETPSAAVNAKFLAKEVDFFSIGTNDLTQYTLAVDRGNELISHLYNPMSPSVLNLIKQVIDASHAEGKWTSMCGELAGDERATILLLGMGLDEFSMSAISVPRIKKLIRNVNYQDAKLLAEKALQQPTAAEIEQLISDFLAEKALN
>LR134327.1|VEF43352.1|1437866_1438367_+|Glucose-specific-phosphotransferase-enzyme-IIA-component
MGLFDKLFGSKDKKAVDVEIYAPLSGEIVNIEDVPDVVFSEKIVGDGVAIRPTGNKLVAPVDGVVGKIFETNHAFSMESKEGVELFVHFGIDTVELKGEGFTRIAQEGQSVKRGDTIIELDLPLLEAKAKSVLTPVVISNMDEISNIEKKSGEVVAGDSVVLVLKK
>LR134327.1|VEF43353.1|1438502_1440542_-|Oligopeptidase-A
MSNPLLTPTDLPAFSKIEPQYIEPAIKQLIEENRATVEHLLKQPHFTWENFILPLAEAGDRLSKVWSPISHLNSVKNSPELREAYQACLPLLAEYGTWVGQHQGLYEAYLQLKNSPEFANYSQAQKKAIENSLRDFKLSGISLPAEKQKRYGEIVARLSELTSQFSNNVLDATMGWEKIIEDESQLKGLPESALQAAKQSAESKGLSYYRFTLEFPSYIPVMTYCENRELREEMYHAFATRASDQGPNAGKWDNSALMQEILSLRVELAKLLDFNTYTELSLATKMAETPQQVLDFLTNLAQRSKAQGKRELQELKDFCKTHYNLTALELWDLTFYSEKQKQHLYAINDEELRPYFPEERVLNGLFELIKRIFHIRAVERHGVETWHKDVRFFDLIDDTNEVRGSFYLDLYAREHKRGGAWMDDCIGRRKTIDGNLQKPVAYLTCNFNRPLGDQPALFTHDEVTTLFHEFGHGLHHMLTKIDVADVAGINGVPWDAVELPSQFMENWCWEEEALQFISGHYQTNEPLPKEKLTQLLKAKNFQAAMFVLRQLEFALFDFRLHHTFDANKSNQVLDTLHQVKAEVAVVPTVDWGRMPHSFSHIFAGGYAAGYYSYLWAEVLSADAYSRFEEEGIFNAQTGQSFLDEILTKGGSEEPMKLFKNFRGREPQLDALLRHKGIAN
>LR134327.1|VEF43355.1|1440674_1441040_+|Inner-membrane-protein-ybaN
MKYFYIGLGFLFLIIGLIGIVLPILPTTPFLLLTVFFFAKGSERVHNWFVGTKIYQNHLKDFHEQRALTKKTKMAILTFSTTMLLIGFYFTPSIIGKSLIIAVLLIKYWFFFFWIKTLEEE
>LR134327.1|VEF43357.1|1441078_1442647_+|Periplasmic-oligopeptide-binding-protein-precursor
MPVAHFPLSAFRLFPFKSVVLFCSVFALNACDKKPQEPVTPPPTIETVQLQLISSQGNRQLLVRGVYSDLVLNPSQAVNAEQFAFLRDLFEGLVIYDQRGNVIPAVAESWQTTDNKTWKFSLRQDAKWSNGEPVTAQQFVASWQALVTSNSPLRHYLAYINLANAESVLKGKLPADKLGIFAENDRTLRLTLDKATPYLPQMLVHISLLPQYLAPHEGIVTNGAYQVAGQENHFIHLEKNPHYWAQDKVAFKHVDYQKIASQQDPIALDLVINPSKTEQAQYFPQLCTYFYAFNMKQPKLAQSSVRKALSMMAPSRNMNNEGKNFIYLSDNFLPISMQTVESHWEQTPMEQLLSQSKISEKAPLKLTLSYDQTELQSKIAQSLIRMWSQSDMIRIIGEGMPRQKLLENIAKGDFQIARSGWCADYNDPAAFLSLFYSHSPDNKSGYHNEEVDRLFEQSLQLMPSAERTTLYSRIEQILQQEKVVLPLYQTTVPIYINPTINGYYLSNPTEVIYSKDLFRKIQ
>LR134327.1|VEF43359.1|1442685_1443483_-|Uncharacterised-protein
MLKTLSKVISSSISMAFLVVLGWSVAYAYGWGQSYFYGFPWWYVDVGSGNVARSLGYVIWATIILLLTYLIGLFGLKKVKPYMSERCVNLLRTYILCTIFFIPIPVACILLVGKLNSIFAIVYIITTFIFTLLFKNYFRNHISTISIHVVIRFFHRNKSYVMLFMYCYFVIFGFIMGYVRPNFKIIFDSMEVEKQSYYVLAKYSYTFILSRSIRATNGDFYIYKMNPNSICHIKVVDIRKLGIDKMAPKEIELKEVKAEEANTEL
>LR134327.1|VEF43361.1|1444598_1445252_-|GTP-cyclohydrolase-2
MAKIELVAQANLPTEFGLFKIVGFEFPDSKKEHVALVLGDISNGDEPVLARIHSECLTGDALHSLKCDCGFQLAAALRQINQEGRGVLIYHREEGRGIGLINKIRAYSLQDQGMDTIEANLALGFAADERNFSVCADIFDLLGVKKIRLLTNNPEKIETMKQAGINVVERVPLNVGENRYNTAYLDTKAKKMGHFIVHNGEQHLMECPYCQEEVPKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134327_1	1.3\|667354\|32\|LR134327\|CRISPRCasFinder	667354-667385	32	NC_019300	Zymomonas mobilis subsp. mobilis NCIMB 11163 plasmid pZMO7, complete sequence	1209-1240	7	0.781
LR134327_1	1.3\|667354\|32\|LR134327\|CRISPRCasFinder	667354-667385	32	NC_013358	Zymomonas mobilis subsp. mobilis NCIMB 11163 plasmid pZA1003, complete sequence	3827-3858	7	0.781
LR134327_1	1.10\|667428\|31\|LR134327\|PILER-CR	667428-667458	31	MN693376	Marine virus AFVG_25M306, complete genome	12088-12118	7	0.774
LR134327_1	1.4\|667419\|33\|LR134327\|CRISPRCasFinder	667419-667451	33	AP013541	Uncultured phage_MedDCM-OCT-S42-C7 DNA, complete genome, group G8, isolate: uvMED-CGR-C97-MedDCM-OCT-S42-C7	20528-20560	8	0.758
LR134327_1	1.10\|667428\|31\|LR134327\|PILER-CR	667428-667458	31	MH791397	UNVERIFIED: Enterococcus phage EfsSzw-1, complete genome	150148-150178	10	0.677

1. spacer 1.3|667354|32|LR134327|CRISPRCasFinder matches to NC_019300 (Zymomonas mobilis subsp. mobilis NCIMB 11163 plasmid pZMO7, complete sequence) position: , mismatch: 7, identity: 0.781

aaaaatggtgaatctgaatttttgggttttaa	CRISPR spacer
aaagtaaatgtatctgaatttttgtgttttaa	Protospacer
***.  ..** ************* *******

2. spacer 1.3|667354|32|LR134327|CRISPRCasFinder matches to NC_013358 (Zymomonas mobilis subsp. mobilis NCIMB 11163 plasmid pZA1003, complete sequence) position: , mismatch: 7, identity: 0.781

aaaaatggtgaatctgaatttttgggttttaa	CRISPR spacer
aaagtaaatgtatctgaatttttgtgttttaa	Protospacer
***.  ..** ************* *******

3. spacer 1.10|667428|31|LR134327|PILER-CR matches to MN693376 (Marine virus AFVG_25M306, complete genome) position: , mismatch: 7, identity: 0.774

tattgttatgtacagaaacacaaaaaatatc	CRISPR spacer
atcttttatatacagaagcacaaaaaatacc	Protospacer
  .* ****.*******.***********.*

4. spacer 1.4|667419|33|LR134327|CRISPRCasFinder matches to AP013541 (Uncultured phage_MedDCM-OCT-S42-C7 DNA, complete genome, group G8, isolate: uvMED-CGR-C97-MedDCM-OCT-S42-C7) position: , mismatch: 8, identity: 0.758

ttattgttatgtacagaaacacaaaaaatatct----	CRISPR spacer
ttgttgttatggacagaaacac----aatgtcaccag	Protospacer
**.******** **********    ***.**

5. spacer 1.10|667428|31|LR134327|PILER-CR matches to MH791397 (UNVERIFIED: Enterococcus phage EfsSzw-1, complete genome) position: , mismatch: 10, identity: 0.677

tattgttatgtacagaaacacaaaaaatatc	CRISPR spacer
attttttaggtacagaaacacaaaaggcgga	Protospacer
  ** *** ****************....

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

473 : 15939

Vibrio_phage(25.0%)

transposase,head

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF40541.1\|473_1046_-\|head	phage head morphogenesis protein, SPP1 gp7 family	C9DGN7	Escherichia_phage	5.4e-57	55.1
VEF40543.1\|1032_1836_-	Mu-like prophage protein gp29	A0A0C4UQR8	Shigella_phage	3.9e-53	44.4
VEF40545.1\|1835_2612_-	Mu-like prophage protein gp29	A0A0C4UQR8	Shigella_phage	1.5e-57	53.3
VEF40547.1\|2621_2975_-	Mu-like prophage FluMu protein gp28	J9RWF2	Pseudomonas_phage	3.3e-09	38.1
VEF40549.1\|2928_4179_-	Mu-like prophage FluMu protein gp28	A0A2I7S9C5	Vibrio_phage	1.1e-147	64.1
VEF40551.1\|4178_4748_-	Protein of uncharacterised function (DUF3486)	A0A2I7S9D1	Vibrio_phage	8.5e-39	45.8
VEF40553.1\|4899_5070_-	Uncharacterised protein	A0A0C4UR00	Shigella_phage	2.2e-11	60.0
VEF40555.1\|5188_5410_-	Protein of uncharacterised function (DUF2730)	NA	NA	NA	NA
VEF40557.1\|5406_5625_-	DnaK suppressor protein	NA	NA	NA	NA
VEF40560.1\|5744_5972_-	Protein of uncharacterised function (DUF2681)	NA	NA	NA	NA
VEF40562.1\|6022_6256_-	Protein of uncharacterised function (DUF2644)	F6MIK0	Haemophilus_phage	2.4e-16	62.3
VEF40564.1\|6915_7041_-	Uncharacterised protein	NA	NA	NA	NA
VEF40566.1\|7387_7540_-	Uncharacterised protein	NA	NA	NA	NA
VEF40569.1\|7565_8009_-	Mu-like prophage protein gp16	NA	NA	NA	NA
VEF40571.1\|7992_8322_-	Uncharacterised protein	F6MIJ5	Haemophilus_phage	3.6e-13	39.4
VEF40573.1\|8345_8531_-	Uncharacterised protein	A0A0M3LPP6	Mannheimia_phage	4.4e-13	58.5
VEF40576.1\|8644_9139_-	Protein of uncharacterised function (DUF551)	NA	NA	NA	NA
VEF40577.1\|9214_9703_-	Uncharacterised protein	NA	NA	NA	NA
VEF40581.1\|9705_10023_-	Uncharacterised protein	A0A2P0P8L3	Salmonella_phage	1.1e-11	44.4
VEF40583.1\|9986_10166_-	Uncharacterised protein	NA	NA	NA	NA
VEF40585.1\|10158_10350_-	Uncharacterised protein	NA	NA	NA	NA
VEF40587.1\|10510_10723_-	Uncharacterised protein	NA	NA	NA	NA
VEF40589.1\|10725_10926_-	Uncharacterised protein	NA	NA	NA	NA
VEF40591.1\|10936_11560_-	Protein of uncharacterised function (DUF3164)	A0A0M3LQ92	Mannheimia_phage	2.6e-65	62.7
VEF40594.1\|11575_11806_-	Uncharacterised protein	NA	NA	NA	NA
VEF40596.1\|11805_12723_-	Mu B transposition protein, C terminal	M4M9P4	Vibrio_phage	4.3e-56	42.5
VEF40598.1\|12757_14764_-\|transposase	Bacteriophage Mu transposase	M4M9R2	Vibrio_phage	1.0e-142	42.7
VEF40600.1\|14778_15030_-	DNA-binding transcriptional regulator Nlp	F6MII4	Haemophilus_phage	2.7e-29	75.6
VEF40602.1\|15240_15939_+	Uncharacterized HTH-type transcriptional regulator HI_1476	F6MII3	Haemophilus_phage	5.3e-75	59.9

DBSCAN-SWA_2

302524 : 335571

Pseudomonas_phage(29.63%)

transposase,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF41183.1\|302524_305311_-	Uncharacterised protein	A0A2D1GNP9	Pseudomonas_phage	3.8e-188	44.9
VEF41185.1\|305310_305517_-	Uncharacterised protein	NA	NA	NA	NA
VEF41187.1\|305520_305772_-	Uncharacterised protein	A0A2D1GNV4	Pseudomonas_phage	2.1e-21	63.2
VEF41189.1\|305784_306594_-	Uncharacterized conserved protein	A0A2D1GNT2	Pseudomonas_phage	4.0e-74	50.9
VEF41191.1\|306647_308339_-	Uncharacterised protein	A0A125RNJ2	Pseudomonas_phage	4.4e-91	35.6
VEF41193.1\|308344_309310_-	Uncharacterised protein	NA	NA	NA	NA
VEF41196.1\|309312_310308_-	Uncharacterised protein	A0A0U3ECM0	Pseudomonas_phage	1.3e-37	35.6
VEF41198.1\|310319_313619_-\|tail	Phage-related minor tail protein	A0A2D1GNK1	Pseudomonas_phage	1.2e-100	30.0
VEF41200.1\|313834_314260_-	Uncharacterised protein	A0A2D1GNY5	Pseudomonas_phage	6.2e-18	36.5
VEF41202.1\|314344_315091_-	Uncharacterised protein	A0A2D1GNQ7	Pseudomonas_phage	8.2e-66	53.6
VEF41204.1\|315077_315263_-	Uncharacterised protein	NA	NA	NA	NA
VEF41207.1\|315265_315700_-	Mu-like prophage protein gp37	A0A0C4UQU7	Shigella_phage	5.2e-28	45.3
VEF41209.1\|315699_316107_-	Mu-like prophage protein gp36	NA	NA	NA	NA
VEF41211.1\|316106_316505_-	Mu-like prophage FluMu protein gp35	NA	NA	NA	NA
VEF41213.1\|316581_317508_-\|head	Mu-like prophage major head subunit gpT	A0A0C4UQR9	Shigella_phage	1.9e-88	53.9
VEF41215.1\|317507_318584_-	Mu-like prophage I protein	C9DGP0	Escherichia_phage	2.4e-66	43.9
VEF41217.1\|318770_319214_-	Mu-like prophage protein gpG	G9BWH2	Planktothrix_phage	3.1e-12	33.6
VEF41219.1\|319340_320678_-\|head	phage head morphogenesis protein, SPP1 gp7 family	C9DGN7	Escherichia_phage	4.9e-85	39.3
VEF41221.1\|320664_322245_-	Mu-like prophage protein gp29	A0A0C4UQR8	Shigella_phage	7.9e-143	50.8
VEF41223.1\|322254_323814_-	Mu-like prophage FluMu protein gp28	A0A2I7S9C5	Vibrio_phage	3.7e-161	61.3
VEF41225.1\|323813_324383_-	Protein of uncharacterised function (DUF3486)	A0A2I7S9D1	Vibrio_phage	8.5e-39	45.8
VEF41227.1\|324405_324705_-	Uncharacterised protein	A0A0C4UR00	Shigella_phage	9.4e-21	54.6
VEF41229.1\|324708_325044_-	Protein of uncharacterised function (DUF2730)	NA	NA	NA	NA
VEF41231.1\|325040_325259_-	DnaK suppressor protein	NA	NA	NA	NA
VEF41232.1\|325378_325663_-	Protein of uncharacterised function (DUF2681)	NA	NA	NA	NA
VEF41234.1\|325655_325889_-	Protein of uncharacterised function (DUF2644)	F6MIK0	Haemophilus_phage	2.4e-16	62.3
VEF41236.1\|325891_326125_-	Uncharacterised protein	NA	NA	NA	NA
VEF41238.1\|326125_326671_-	N-acetylmuramoyl-L-alanine amidase	F6MIJ9	Haemophilus_phage	2.2e-76	70.4
VEF41240.1\|326749_327169_-	Uncharacterized conserved protein	NA	NA	NA	NA
VEF41242.1\|327165_327639_-	Mu-like prophage protein gp16	NA	NA	NA	NA
VEF41244.1\|327622_328162_-	Uncharacterised protein	A0A0M3LPP6	Mannheimia_phage	6.2e-47	51.4
VEF41246.1\|328277_328772_-	Protein of uncharacterised function (DUF551)	NA	NA	NA	NA
VEF41248.1\|328774_329335_-	Uncharacterised protein	A0A0M3LP85	Mannheimia_phage	1.2e-13	26.5
VEF41250.1\|329337_329655_-	Uncharacterised protein	A0A2P0P8L3	Salmonella_phage	1.1e-11	44.4
VEF41252.1\|329618_329798_-	Uncharacterised protein	NA	NA	NA	NA
VEF41254.1\|329790_329982_-	Uncharacterised protein	NA	NA	NA	NA
VEF41256.1\|330142_330355_-	Uncharacterised protein	NA	NA	NA	NA
VEF41258.1\|330357_330558_-	Uncharacterised protein	NA	NA	NA	NA
VEF41261.1\|330568_331192_-	Protein of uncharacterised function (DUF3164)	A0A0M3LQ92	Mannheimia_phage	2.6e-65	62.7
VEF41263.1\|331207_331438_-	Uncharacterised protein	NA	NA	NA	NA
VEF41265.1\|331437_332355_-	Mu B transposition protein, C terminal	M4M9P4	Vibrio_phage	4.3e-56	42.5
VEF41266.1\|332389_334396_-\|transposase	Bacteriophage Mu transposase	M4M9R2	Vibrio_phage	1.0e-142	42.7
VEF41268.1\|334410_334662_-	DNA-binding transcriptional regulator Nlp	F6MII4	Haemophilus_phage	2.7e-29	75.6
VEF41270.1\|334872_335571_+	Uncharacterized HTH-type transcriptional regulator HI_1476	F6MII3	Haemophilus_phage	5.3e-75	59.9

DBSCAN-SWA_3

1060795 : 1070845

Serratia_phage(16.67%)

integrase

attL 1060721:1060737|attR 1073433:1073449

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1060721:1060737	attL	NA	NA	NA	NA
VEF42584.1\|1060795_1062811_+	DNA ligase	A0A289ZTZ3	Serratia_phage	1.0e-142	49.4
VEF42586.1\|1062996_1063575_-	Thymidine kinase	A0A076YPF1	Citrobacter_phage	5.2e-52	51.6
VEF42589.1\|1063577_1063811_-	Uncharacterised protein	NA	NA	NA	NA
VEF42591.1\|1063882_1064911_-	t(6)A37 threonylcarbamoyladenosine biosynthesis protein	A0A0R6PI74	Moraxella_phage	6.1e-112	58.6
VEF42593.1\|1065135_1065351_+	30S ribosomal protein S21	NA	NA	NA	NA
VEF42595.1\|1065473_1067252_+	DNA primase	A0A1S5RF71	Helicobacter_phage	5.6e-44	31.6
VEF42598.1\|1067323_1069195_+	Sigma-70	A0A2I7SAT0	Vibrio_phage	1.0e-35	33.5
VEF42601.1\|1069603_1070845_+\|integrase	Prophage CP4-57 integrase	A0A1B5FPC6	Escherichia_phage	8.3e-71	38.0
1073433:1073449	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2328349 : 2337105

Pseudomonas_phage(100.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF44963.1\|2328349_2331136_-	Uncharacterised protein	A0A2D1GNP9	Pseudomonas_phage	3.8e-188	44.9
VEF44965.1\|2331135_2331342_-	Uncharacterised protein	NA	NA	NA	NA
VEF44967.1\|2331345_2331597_-	Uncharacterised protein	A0A2D1GNV4	Pseudomonas_phage	2.1e-21	63.2
VEF44969.1\|2331609_2332419_-	Uncharacterized conserved protein	A0A2D1GNT2	Pseudomonas_phage	4.0e-74	50.9
VEF44972.1\|2332472_2334164_-	Uncharacterised protein	A0A125RNJ2	Pseudomonas_phage	4.4e-91	35.6
VEF44974.1\|2334169_2334490_-	Uncharacterised protein	NA	NA	NA	NA
VEF44976.1\|2334666_2335134_-	Uncharacterised protein	NA	NA	NA	NA
VEF44978.1\|2335938_2336133_-	Uncharacterised protein	A0A0U3ECM0	Pseudomonas_phage	2.5e-06	60.9
VEF44980.1\|2336340_2337105_-\|tail	Phage-related minor tail protein	A0A125RNI9	Pseudomonas_phage	4.2e-25	30.0

Anti-CRISPR protein detection

Acr_ID: LR134327.1|VEF41171.1|300085_300319_-|Uncharacterised-protein

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Acr_ID: LR134327.1|VEF44951.1|2325910_2326144_-|Uncharacterised-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LR134327.1|VEF41171.1|300085_300319_-|Uncharacterised-protein

300085_300319_-

77 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|9	0.44285714285714284	0.922077922077922	0.9117647058823529

LR134327.1|VEF44951.1|2325910_2326144_-|Uncharacterised-protein

2325910_2326144_-

77 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|9	0.44285714285714284	0.922077922077922	0.9117647058823529

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134327

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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Click the colored protein region to show detailed information