CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134341	Streptococcus pseudoporcinus strain NCTC13786 genome assembly, chromosome: 1	2 crisprs	csa3,csm6,csn2,cas2,cas1,cas9,RT,cas3,cas4,cas7,cas8c,cas5,DEDDh,DinG	1	9	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134341_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134341_1

388740-389368

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CRT
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	PILER-CR

9 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of LR134341_1

>merge|LR134341|1|388740-389368|CRISPRCasFinder,CRT,PILER-CR
TCATTGGAATTATTCAAAATAATATAGCTCTAAAACACTCCAGTTCCAGATCCAACTCCAGATCCAGTTTTGGAATCATTCAAAATAACATAGCTCTAAAACTTACTCATTAAGTATATCATGAAAAAAGAGTTTTGGAATCATTCAAAATAACATAGCTCTAAAACTGGTTGCTACGAGTAAACTCAGCACGTAAGGTTTTGGAATCATTCAAAATAACATAGCTCTAAAACTCATACTCCAACCACATTGAGATTTTATCAGTTTTGGAATTATTCAAAATAACATAGCTCTAAAACGTTCTGCCGATACACGATTGAGCGCCAGCTGTTTTGGAATCATTCAAAATAAGATAGCTCTAAAATTATTTATCTTTTTACCAAGCTGATTTACTAGTTTTGGAATCATTCAAAATAACATAGCTCTAAAACCAGTTTAAACTCGCTGTTATGAAGCAAGTCGTTTTGGAATCATTCAAAATAACATAGCTCTAAAACCTCAGTTAATTCTGGGCGGTTTTTTGTGTGGTTTTGGAATCATTCAAAATAACATAGCTCTAAAACAAAAAATTGTACCTGCAATGGAAAGACGAAGTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC

>LR134341|1|1|388740-389368|CRISPRCasFinder
TCATTGGAATTATTCAAAATAATATAGCTCTAAAAC	ACTCCAGTTCCAGATCCAACTCCAGATCCA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TTACTCATTAAGTATATCATGAAAAAAGA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TGGTTGCTACGAGTAAACTCAGCACGTAAG
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TCATACTCCAACCACATTGAGATTTTATCA
GTTTTGGAATTATTCAAAATAACATAGCTCTAAAAC	GTTCTGCCGATACACGATTGAGCGCCAGCT
GTTTTGGAATCATTCAAAATAAGATAGCTCTAAAAT	TATTTATCTTTTTACCAAGCTGATTTACTA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CAGTTTAAACTCGCTGTTATGAAGCAAGTC
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CTCAGTTAATTCTGGGCGGTTTTTTGTGTG
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	AAAAAATTGTACCTGCAATGGAAAGACGAA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC

>LR134341|1|1|388740-389368|CRT
TCATTGGAATTATTCAAAATAATATAGCTCTAAAAC	ACTCCAGTTCCAGATCCAACTCCAGATCCA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TTACTCATTAAGTATATCATGAAAAAAGA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TGGTTGCTACGAGTAAACTCAGCACGTAAG
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TCATACTCCAACCACATTGAGATTTTATCA
GTTTTGGAATTATTCAAAATAACATAGCTCTAAAAC	GTTCTGCCGATACACGATTGAGCGCCAGCT
GTTTTGGAATCATTCAAAATAAGATAGCTCTAAAAT	TATTTATCTTTTTACCAAGCTGATTTACTA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CAGTTTAAACTCGCTGTTATGAAGCAAGTC
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CTCAGTTAATTCTGGGCGGTTTTTTGTGTG
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	AAAAAATTGTACCTGCAATGGAAAGACGAA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC

>LR134341|1|1|388806-389368|PILER-CR
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TTACTCATTAAGTATATCATGAAAAAAGA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TGGTTGCTACGAGTAAACTCAGCACGTAAG
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	TCATACTCCAACCACATTGAGATTTTATCA
GTTTTGGAATTATTCAAAATAACATAGCTCTAAAAC	GTTCTGCCGATACACGATTGAGCGCCAGCT
GTTTTGGAATCATTCAAAATAAGATAGCTCTAAAAT	TATTTATCTTTTTACCAAGCTGATTTACTA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CAGTTTAAACTCGCTGTTATGAAGCAAGTC
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	CTCAGTTAATTCTGGGCGGTTTTTTGTGTG
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC	AAAAAATTGTACCTGCAATGGAAAGACGAA
GTTTTGGAATCATTCAAAATAACATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134341.1\|VEF93107.1\|385352_385955_-\|putative-lipoprotein	unknown	unknown	gnl\|CDD\|289729
LR134341.1\|VEF93111.1\|390120_390465_-\|CRISPR-associated-protein-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LR134341.1\|VEF93103.1\|379786_380440_-\|metal-dependent-phosphohydrolase	unknown	unknown	gnl\|CDD\|224336
LR134341.1\|VEF93118.1\|399148_399817_-\|acetyltransferase-GNAT-Family	unknown	unknown	gnl\|CDD\|224584
LR134341.1\|VEF93104.1\|380436_380889_-\|methionine-sulfoxide-reductase-B	unknown	unknown	gnl\|CDD\|234692
LR134341.1\|VEF93117.1\|397973_399104_-\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
LR134341.1\|VEF93110.1\|389597_390131_-\|CRISPR-associated-family-protein	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
LR134341.1\|VEF93115.1\|396453_397218_-\|haloacid-dehalogenase	unknown	unknown	gnl\|CDD\|319832
LR134341.1\|VEF93100.1\|377150_378005_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
LR134341.1\|VEF93112.1\|390461_391328_-\|CRISPR-associated-protein-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
LR134341.1\|VEF93116.1\|397228_397963_-\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
LR134341.1\|VEF93105.1\|381041_382874_-\|GTP-binding-protein-LepA	unknown	unknown	gnl\|CDD\|235462
LR134341.1\|VEF93114.1\|395812_396454_-\|TIGR01906-family-protein	unknown	unknown	gnl\|CDD\|226884
LR134341.1\|VEF93113.1\|391327_395452_-\|CRISPR-associated-protein,-Csn1-family	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
LR134341.1\|VEF93101.1\|378111_379275_-\|Predicted-lipase	unknown	unknown	gnl\|CDD\|371412
LR134341.1\|VEF93119.1\|399883_401236_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
LR134341.1\|VEF93108.1\|386508_386949_-\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
LR134341.1\|VEF93102.1\|379345_379738_-\|GNAT-family-acetyltransferase	unknown	unknown	gnl\|CDD\|173926
LR134341.1\|VEF93106.1\|383521_385330_+\|glucan-binding-protein	unknown	unknown	gnl\|CDD\|369899
LR134341.1\|VEF93109.1\|388207_388642_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085

Protein	Function_ID	Function_description	E-value
LR134341.1\|VEF93107.1\|385352_385955_-\|putative-lipoprotein	gnl\|CDD\|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	1.89121e-22
LR134341.1\|VEF93111.1\|390120_390465_-\|CRISPR-associated-protein-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.33609e-45
LR134341.1\|VEF93103.1\|379786_380440_-\|metal-dependent-phosphohydrolase	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	4.01434e-30
LR134341.1\|VEF93118.1\|399148_399817_-\|acetyltransferase-GNAT-Family	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	4.15627e-11
LR134341.1\|VEF93104.1\|380436_380889_-\|methionine-sulfoxide-reductase-B	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	3.6431e-86
LR134341.1\|VEF93117.1\|397973_399104_-\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
LR134341.1\|VEF93110.1\|389597_390131_-\|CRISPR-associated-family-protein	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.88304e-87
LR134341.1\|VEF93115.1\|396453_397218_-\|haloacid-dehalogenase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.75594e-127
LR134341.1\|VEF93100.1\|377150_378005_-\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	2.35973e-112
LR134341.1\|VEF93112.1\|390461_391328_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.12672e-123
LR134341.1\|VEF93116.1\|397228_397963_-\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	2.17332e-91
LR134341.1\|VEF93105.1\|381041_382874_-\|GTP-binding-protein-LepA	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
LR134341.1\|VEF93114.1\|395812_396454_-\|TIGR01906-family-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	2.14569e-56
LR134341.1\|VEF93113.1\|391327_395452_-\|CRISPR-associated-protein,-Csn1-family	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
LR134341.1\|VEF93101.1\|378111_379275_-\|Predicted-lipase	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	2.78078e-81
LR134341.1\|VEF93119.1\|399883_401236_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
LR134341.1\|VEF93108.1\|386508_386949_-\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	7.68739e-13
LR134341.1\|VEF93102.1\|379345_379738_-\|GNAT-family-acetyltransferase	gnl\|CDD\|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	2.26876e-11
LR134341.1\|VEF93106.1\|383521_385330_+\|glucan-binding-protein	gnl\|CDD\|369899	pfam08481, GBS_Bsp-like, GBS Bsp-like repeat. This domain is found as a repeat in a number of Streptococcus proteins including some hypothetical proteins and Bsp. Bsp is a protein of group B Streptococcus (GBS) which might control cell morphology.	4.31693e-21
LR134341.1\|VEF93109.1\|388207_388642_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.54838e-76

>LR134341.1|VEF93109.1|388207_388642_-|nucleoside-diphosphate-kinase
MEKTFFMIKPDGVQRGLMGQILRRIERRGFRIEQLQMIRPSRELLDSHYQHLRGKVFYPSLLDYMMSGPLLIGILSGSDVIASWRTMMGETNPKDALPGTIRGDFAQAPEANAPMMNCVHGSDSLDSARREIELWFGGATEDSN
>LR134341.1|VEF93108.1|386508_386949_-|GtrA-family-protein
MKVIKKFLNNEVISYLIFGVMTTLVYVIMRVIIFNLTTLASLSATLASIISILFAFVTNDIIVFKQAREGWFKRLIKFFAARLLTLLLDVALAYLLVEKFPYLIGQFVKNDIHMVNTIETLLGQVLIIVLNYVLSKLFVFRDKSPL
>LR134341.1|VEF93107.1|385352_385955_-|putative-lipoprotein
MKKNLLYGLLIISSLTLVSCSSTDASKGNISTSKIVKKSAKKMTKGEKMKNSLTHVKVGDFNKGGKDGSSKDEVVKLLGKETSATKNDTVETLMWKTGKVRIDVGFINNKVVSKAITGFLYKRDKVISLDDFDAIKTKTSYEIVTDKYGQPDELATTVMNGSEQTTGVWYSNIKGENDKANMTLNFTDGKLTQKNQIGIK
>LR134341.1|VEF93106.1|383521_385330_+|glucan-binding-protein
MSKHKAYLATAALLTSLLLNNSIINADSTNNTNSGTPPTSSMQIPPSSSVKDNSSALDTTTRTETTTPQALTNITPTINDYDSHSDTFTVEAKGDSTTKTIKGFRVAIWSEENGNDDLKWFTVDRITNNSAQVKFNVKDFNYKPGNYIIHAYIDYTDGTTSGTNFGTRNISVYNPTITSDINNIMIRANRAIPAGVEGKVAIWSKANDQDDLKWYTIKPDGTLDIPLSELKGGMGDYNVHVYFNQDNQKVYGLASTVTINPVPQSLSISKKDNLTYDLILSNVPSYYKDINIPVWSEADGQDDLVWTAATKISSNQYKITINLRDHKYNLGKYNVGAYATNTMTGKTNQGLTSTTFETDKTFVGVDNYNGINGKFDVVASPVDNEKAVKAIRVAVWSQAMQENLFWYQVNEKSANGLFTAHVDVKNHKNIAGTYHVAVYVDHTDGSTTGYNLTDQQLSSVKLGVSYSGVNSYTFPEQYRGLLANPLPNGQTYPGNAYAPGQCTWYVYNRFAQLGINIYAYLGNANQWPSNALIQHYGIGKTPRVGAAVIFPKDGNGWGHVGFVEHVNADGSFLFSESNYNNALYQVHWRESWVTSDLIFIYP
>LR134341.1|VEF93105.1|381041_382874_-|GTP-binding-protein-LepA
MNSQELKQRQAKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYILHLIDTPGHVDFTYEVSRSLAACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEVEDVIGLDASEAVLASAKAGIGIEEILEQIVDKVPAPSGDVDAPLQALIFDSAYDAYRGVILQVRIINGIVKPGDKIQLMSNGKTFDVTEVGIFTPKTVGRQFLATGDVGYIAASIKTVADTRVGDTVTLANNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHINTTDGDMLAVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRKSQLVKMDILLNAEKVDALSFIVHREFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDSKK
>LR134341.1|VEF93104.1|380436_380889_-|methionine-sulfoxide-reductase-B
MEDKEVLRKRIGDLAYEVTQEAATEPAFTGQYDNFFEKGIYVDVVSGEVLFSSLDKYQSGCGWPAFTKPVENRLVTNHEDSSFGMHRVEVRSRKAQSHLGHVFNDGPKDRGGLRYCINSAALRFIPYDQLEAEGYAQYLDLFTNEEGRDR
>LR134341.1|VEF93103.1|379786_380440_-|metal-dependent-phosphohydrolase
MKANQASILAQTAEWVKAKLAGEASGHDWWHIVRVVNSTKKIAEIEGADPFICQMAALLHDMADEKLTADPQAADQEVADFLLSKKLSADDIAEILYITRHISFKAGKGQKLASLSARIVQDADRLDAIGAIGIARCMAYSGYKGRLIHDPERQARTHLTVAQYRNGQDTAIMHFYEKLLLLKDSMNTDFGRQLAQQRHQFLELYLEEFYAEWDGLR
>LR134341.1|VEF93102.1|379345_379738_-|GNAT-family-acetyltransferase
MSAIEALLREISQVHHEVRPDLFKPESLKFSLEDLVERLGNLDKPIFVYEEDGKVLGHLFLEFKICDKNGPYPKTSLYIDDLCVAQESRHRGIGQKLLQFAESYGRSQGAYQFYDNAGFRPQQIQMGKML
>LR134341.1|VEF93101.1|378111_379275_-|Predicted-lipase
MPVLRDYIIKQSKASFKSLPLNELDIIAINEIGYLSFDDLAGIRIDEKTEISIKDIKKATSLDCQKTIYNYLITKERLELFEAMQGSQRFQDLALSHYVNEVDREFEKQFAAMVFTIPSINHVQIVFRGTDDSVIGWKEDFKLTYMSEIPAQRSAISYLSSYIGSHPSQEVFVTGHSKGGNLALYASCFLLPPFQAKIKKIYALDSPGLPEKLLQREAYKAVRRRLVIIRPQESIVGVMLYCDVKPKVVKSLAYGLLQHKTCNWQVDPEGSLVTVPSQTELSLSLEKTFKDWTKQLSKQDLKLVCDSFFDTLISSGITSLNAFSFDEKAFATFFKVISSLRSIDQAKKMIMLKSIRQLIHDYTGYRKRAVTKKIEKRMGHFLKKEHR
>LR134341.1|VEF93100.1|377150_378005_-|aldo/keto-reductase
MIETFKMSDGNRIPSLGVGTWLISDEKAEVLVSQALKLGYRHIDTAQAYGNEVGVGKGLFLSGLPREEIFLTSKVAAELKSYQAVTASIDASLNKLGLNDIDLMLIHSPQPWNKWRDKTNDYDQGNLEAWRALEDAQKAGKVKSIGLSNFLREDIENILKNGQVKPAVNQILTHVGNVPFDLIEYCQREGILLEAYSPIAHGQVLKDKTIQELAKKYAVSPASLCIKYVHQLGMVALPKTENPEHLLSNMMLDFNISRHDMALLNKLQFTDYGNYSTFPVFSGK
>LR134341.1|VEF93110.1|389597_390131_-|CRISPR-associated-family-protein
MNLNLPILDQPLPLESHTILAIENVSLYATLVSYFYQYTETSHLKLFDKKLKALKESEIMIITDVLGYDVNAPGLLKMVHADLEEQLNEKPEVKSMVDKLAATITELIAFEYLENELDLEYDEITVLELIKALGVKVETRSDTIFEKCLEILQIFKYLNKKKLLIFVNCGSYLNQEE
>LR134341.1|VEF93111.1|390120_390465_-|CRISPR-associated-protein-Cas2
MSYRYMRMLLMFDMPTDTVDDRKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNSANLAMIDRLQENNPKKGTITLLTVTEKQFARMIYLNGSRNTAIANSDSRIIFLGEDYCDES
>LR134341.1|VEF93112.1|390461_391328_-|CRISPR-associated-protein-Cas1
MGWRTLVVNSHSKLSYKNNHLIFKDTSRTELIHLSEIDVLLLETTDIVLTTMLIKRLVDENVLVIFCDDKRLPTAVLTPFYGRHDSSLQLSKQISWSNDLKAQVWTQIIAQKILNQSLFLGACGYYEKSQSIIELYNGLEVFDPSNREGHSARIYFNTLFGRDFSRHQDNVINAGLDYGYTLLLSLFARELVMTGCMTQFGLKHSNQFNHFNFASDIMEPFRPIVDQIVYENRSLSFVQMKRQLFAIFSNTYSYYHKEMYLSNIVSDYTKKVVKALNNGGEGVPKFRI
>LR134341.1|VEF93113.1|391327_395452_-|CRISPR-associated-protein,-Csn1-family
MKKRYSYSIGLDIGTNSVGWAVINEDYKVPAKKMTVFGNTDRKTIKKNLLGTVLFDSGETAQARRLKRTNRRRYTRRRYRLCQLQNIFATEMVKVDDTFFQRLSESFFYYQDKAFDKHPIFGNSKEERAYHKTYPTIYHLRKDLADRDQKADLRLIYLALSHIIKFRGHFLIEGKLNSENTDVQKLFIALVTVYNLLFEEEPIAGETCDAKALLTAKTSKSKRLESLISEFPGQKKNGLFGNLLALALGLRPNFKSNFGLSEDAKLQITKDTYEEELDNLLAEIGDHYADLFLAAKNLSDAILLSDILTLSDENTRAPLSASMIKRYEEHQEDLALLKKLVKEQMPEKYWEIFSNAKKNGYAGYIEGKVSQEDFYRYIKPILSRLKGGDEFLAKIDRDDFLRKQRTFDNGSIPHQIHLKELHAILRRQEKYYPFLAEQKEKIEQLLCFRIPYYVGPLAKGGNSSFAWLKRRSDEPITPWNFKDVVDEEASAQAFIEGMTNYDTYLPEEKVLPKHSPLYEMFTVYNELTKVKYIAENMTKPLYLSAEQKEAIIDHLFKQTRKVTVKDLKEKYFSQIEGLENVDVTGVEGAFNASLGTYNDLLKIIKDKAFLDDEANAEILEEIVLILTLFQDEKLIEKRLAKYANLFEKSVLKKLRKRHYRGWGRLSRQLIDGMKDKASGKTILDFLKADDFANRNFIQLINDSSLDFEKLIDDAQKKAIKRESLTEAVANLAGSPAIKKGILQSLKVVDEIVKVMGHNPDNIVIEMSRENQTTAQGLKNARQRLKKIKEVHKKTGSRILEDNSERITNLTLQDNRLYLYLLQDGKDMYTGQDLDINNLSQYDIDHIIPQSFIKDNSIDNLVLTTQKANRGKSDNVPSIEVVRDMKDRVWRRQLANGAISRQKFDHLTKAERGGLADSDKARFLRRQLVETRQITKHVAQLLDSRFNSKSNQNKKLARNVKIITLKSKIVSDFRKDFGLYKLREVNNYHHAHDAYLNAVVGTALLKKYPKLEAEFVYGDYKHFDLVKLISKSDPSLGKATAKVFFYSNIMNFFKEELSLADGTLMKRPVIETNTETGEVVWDKVKDFKTIRKVLSYPQVNIVKKTEIQSGAFSKESVLSKGNSDKLIERKKGWDPKKYGGFDSPNTAYSIFVVAKVAKRKAQKLKTVKEIVGITIMEQAEYEKDNIAFLEKKGYQDIQEKLLIKLPKYSLFELENGRRRLLASANEFQKGNELALSGKYMKFLYLASRYDKLSSKIESEQQKKLFVEQHLHYFDEILDIVVKHATCYIKAENNLKKIISLYKKKEAYSINEQALNMLNLFIFTSLGAPSTFVFFDETIDRKRYTTSSDVLNGILIQQSITGLYETRIDLSRFGGD
>LR134341.1|VEF93114.1|395812_396454_-|TIGR01906-family-protein
MKEKVSLVSTFIWLLSASVLLTIYLAWLAYPLEVDYLKISQTVYMTKKSILNNFNGLMQYLTNPLVKDLHFASFTASKAGLAHFADVKGLFQLTQALFLVTSIPALLFLSQTIKHQSLGLFRRQLLMAILLPFALALFATFLGFDQFFVFFHKILFAGKDNWVFDPLTDPVIWILPESFFMHCFILFFTLYEAFLLGLYWLGSKIDRNKKQAR
>LR134341.1|VEF93115.1|396453_397218_-|haloacid-dehalogenase
MSYKGYLIDLDGTIYKGKERIPAGENFIKRLQQKGIPYLLVTNNTTRRPEMIQSMLAEQFQVETSLESIYTATMATVDYMNDMKRGKTAYVIGEAGLKTAIAEAGYQEDTENPAYVVVGLDSQVTYDMLARATLAIAKGALFIGTNPDLNIPTERGLMPGAGSLVALLEAATRVQPVFIGKPNAIIMNKALAILGVDRSEALMVGDNYLTDIMAGIQNDIATLLVTTGFTKPEEVATLPTQPHHVVASLDEWDV
>LR134341.1|VEF93116.1|397228_397963_-|acyl-ACP-thioesterase
MGLPYKESFTMPFDLCDVKHDAKLPLLLAYCLTVSGRQSQLLGRSDAYLLEQFQLVWIITDYEVKIKRLPLFNETITIQTEALSYNKLFCYRQFDIYDQEGNQLADILTYFALMNPETRKVAPIPEEVVAPYQTEFVKKIRRAFKAAPLENPKSKDYHVRYFDIDMNGHVNNSKYLDWIYDSLGYDFLRHHNPVSLRLKYVKEVAPGGQIRSLYVQEDLTTRHEIVSDGQVNAQAIIQWQKIEK
>LR134341.1|VEF93117.1|397973_399104_-|coproporphyrinogen-III-oxidase
MIKKPSSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIAEFRSYQIKHLKTLYIGGGTPTAISAQQLDYLLTELTRDLDLANLEEFTIEANPGDLDAEKIAVLQKSAVNRVSLGVQTFNDKHLKQIGRSHNEAQIYETIDSLKAAGFHNISIDLIYALPGQTLEQVKENVAKAVALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFDYIIQEMEAHGFEHYEISNFGKPGYYSQHNLMYWNNDEYYGCGAGASGYLDGMRYRNRVPIQHYLKAVQAGNARLTEEVLTLEEMMEEELFLGLRKKTGVSIAQFEAKFPFTFKERYGRIVEELVAQGLLVDDPQRVRMTRRGLFLGDSVAEKFILK
>LR134341.1|VEF93118.1|399148_399817_-|acetyltransferase-GNAT-Family
MHSKREDILRRLDPKASAYFRAIIPEYQKGYIDYIYQTEDYAIQGRRLKYISKLFQVWQDKPWYYLMPLSQEAIERIAHDWQYPSPYDFYNLTAALDEYEKMLRPDLGQEAYVQVIRNGILFGFASFEKQGEDLEIGLGMAPEWTGQSYGPDFLKAIEDYVIATYQVEKLVVNVAAFNQRGRRLSLKCGYEEEGHFDQVTNGAVYDFVRMTKLVSAPSLSKK
>LR134341.1|VEF93119.1|399883_401236_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTENASAGVMISASHNPALDNGIKFFGSDGFKLADDQELEIEALLDAQEDNLPRPSAQGLGSLVDYPEGLRKYEKFLVSTGLDLEGMKVALDTANGAASATARDIFLDLQADITVIGESPDGLNINDGIGSTHPEQLQALVLENGSDIGLAFDGDSDRLIAVDEKGEIVDGDKVMFIIGKYLSEKGLLAQNTIVTTVMSNLGFHKALDQHGIKKAVTAVGDRYVVEEMRRSHYNLGGEQSGHVIIMDYNTTGDGQLTAIQLTKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDKAMEVPAIAAIIEKMETEMEGNGRILVRPSGTEPLLRVMAEAPTDEAVDYYVDTIADVVRREIGIA

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Crispr_ID: LR134341_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134341_3

780923-781747

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	CRT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	PILER-CR

12 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of LR134341_3

>merge|LR134341|3|780923-781747|CRISPRCasFinder,CRT,PILER-CR
ATTATTACCAAACACACCGTGAGGGGTGCGACTTCTTTATCTTGGGACTAATGATGAAGATACTATATTTCAATCCACACACCCGTGAGGGGTGCGACAAATGATGTATCGTTTGAAGGATACGGAAAATCAATTTCAATCCACGCACCCGTGAGGGGTGCGACGTTTGACTACTCTACATGTTAAATTACAAAATGAATTTCAATCCACGCACCCGTGAGGGGTGCGACTCAATACGTTCTTGATCTTTTGCTTTATTAGACGTATTTCAATCCACGCACCCGTGAGGGGTGCGACGCAAGTTAAAGCGTTCGTCCTCTGCTCGATTTGGATTTCAATCCACGCACCCGTGAGGGGTGCGACATGATTCATAAAGCTTTGCTTAACTCTGTCTCAGGATTTCAATCCACGCACCCGTGAGGGGTGCGACTCCACCGCTTGGTGTTGTTGCTTGCAATGTTTTTGATTTCAATCCACGCACCCGTGAGGGGTGCGACAACTTACAAAAAGTCTGACAAAAATATTTATACAATTTCAATCCACGCACCCGTGAGGGGTGCGACAAGAGTGCTTGATTATATCAAAAGACATGATGGATTTCAATCCACGCACCCGTGAGGGGTGCGACATTTTTATTGTTGTATTTTTCTCTGATTGCTTTTATTTCAATCCACGCACCCGTGAGGGGTGCGACGATGATGAAGTGGAACAATCATCTAAATCTTCGATTTCAATCCACGCACCCGTGAGGGGTGCGACATTTGGAAATTTGGTAGCATATCAGGTCGGTAAAATTTCAATCCACGCACCCGTGAGGGGTGCGAC

>LR134341|3|3|780923-781747|CRISPRCasFinder
ATTATTACCAAACACACCGTGAGGGGTGCGAC	TTCTTTATCTTGGGACTAATGATGAAGATACTAT
ATTTCAATCCACACACCCGTGAGGGGTGCGAC	AAATGATGTATCGTTTGAAGGATACGGAAAATCA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GTTTGACTACTCTACATGTTAAATTACAAAATGA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	TCAATACGTTCTTGATCTTTTGCTTTATTAGACGT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GCAAGTTAAAGCGTTCGTCCTCTGCTCGATTTGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATGATTCATAAAGCTTTGCTTAACTCTGTCTCAGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	TCCACCGCTTGGTGTTGTTGCTTGCAATGTTTTTG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	AACTTACAAAAAGTCTGACAAAAATATTTATACA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	AAGAGTGCTTGATTATATCAAAAGACATGATGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATTTTTATTGTTGTATTTTTCTCTGATTGCTTTT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GATGATGAAGTGGAACAATCATCTAAATCTTCG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATTTGGAAATTTGGTAGCATATCAGGTCGGTAAA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC

>LR134341|3|2|780923-781747|CRT
ATTATTACCAAACACACCGTGAGGGGTGCGAC	TTCTTTATCTTGGGACTAATGATGAAGATACTAT
ATTTCAATCCACACACCCGTGAGGGGTGCGAC	AAATGATGTATCGTTTGAAGGATACGGAAAATCA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GTTTGACTACTCTACATGTTAAATTACAAAATGA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	TCAATACGTTCTTGATCTTTTGCTTTATTAGACGT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GCAAGTTAAAGCGTTCGTCCTCTGCTCGATTTGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATGATTCATAAAGCTTTGCTTAACTCTGTCTCAGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	TCCACCGCTTGGTGTTGTTGCTTGCAATGTTTTTG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	AACTTACAAAAAGTCTGACAAAAATATTTATACA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	AAGAGTGCTTGATTATATCAAAAGACATGATGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATTTTTATTGTTGTATTTTTCTCTGATTGCTTTT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GATGATGAAGTGGAACAATCATCTAAATCTTCG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATTTGGAAATTTGGTAGCATATCAGGTCGGTAAA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC

>LR134341|3|2|780989-781747|PILER-CR
ATTTCAATCCACACACCCGTGAGGGGTGCGAC	AAATGATGTATCGTTTGAAGGATACGGAAAATCA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GTTTGACTACTCTACATGTTAAATTACAAAATGA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	TCAATACGTTCTTGATCTTTTGCTTTATTAGACGT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GCAAGTTAAAGCGTTCGTCCTCTGCTCGATTTGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATGATTCATAAAGCTTTGCTTAACTCTGTCTCAGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	TCCACCGCTTGGTGTTGTTGCTTGCAATGTTTTTG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	AACTTACAAAAAGTCTGACAAAAATATTTATACA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	AAGAGTGCTTGATTATATCAAAAGACATGATGG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATTTTTATTGTTGTATTTTTCTCTGATTGCTTTT
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	GATGATGAAGTGGAACAATCATCTAAATCTTCG
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC	ATTTGGAAATTTGGTAGCATATCAGGTCGGTAAA
ATTTCAATCCACGCACCCGTGAGGGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134341.1\|VEF93462.1\|779088_780759_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|225519
LR134341.1\|VEF93463.1\|781894_782188_-\|CRISPR-associated-protein-cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
LR134341.1\|VEF93461.1\|778333_779101_-\|transcriptional-regulator,-AraC-family	unknown	unknown	gnl\|CDD\|227095
LR134341.1\|VEF93465.1\|783222_783891_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|224385
LR134341.1\|VEF93460.1\|777223_778258_-\|Sip11	unknown	unknown	gnl\|CDD\|270264
LR134341.1\|VEF93472.1\|794294_794861_-\|shikimate-kinase	unknown	unknown	gnl\|CDD\|379324
LR134341.1\|VEF93453.1\|770060_770777_-\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
LR134341.1\|VEF93466.1\|783892_784741_-\|CRISPR-associated-protein	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
LR134341.1\|VEF93455.1\|771895_772816_-\|CorA-like-Mg2+-transporter-protein	unknown	unknown	gnl\|CDD\|213361
LR134341.1\|VEF93467.1\|784744_786631_-\|CRISPR-associated-protein	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773
LR134341.1\|VEF93469.1\|787882_790288_-\|CRISPR-associated-helicase	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
LR134341.1\|VEF93458.1\|774469_776134_-\|ABC-transporter,-permease-protein	unknown	unknown	gnl\|CDD\|224099
LR134341.1\|VEF93456.1\|772879_773839_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|223745
LR134341.1\|VEF93454.1\|770804_771884_-\|cytoplasmic-protein	unknown	unknown	gnl\|CDD\|225197
LR134341.1\|VEF93468.1\|786630_787368_-\|CRISPR-associated-protein	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
LR134341.1\|VEF93471.1\|791572_794224_-\|valyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|235582
LR134341.1\|VEF93457.1\|774057_774255_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134341.1\|VEF93459.1\|776134_777214_-\|ABC-transporter,-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
LR134341.1\|VEF93470.1\|790927_791131_-\|IS200-transposase	unknown	unknown	gnl\|CDD\|376616
LR134341.1\|VEF93464.1\|782197_783223_-\|CRISPR-associated-protein-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360

Protein	Function_ID	Function_description	E-value
LR134341.1\|VEF93462.1\|779088_780759_-\|histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	9.78532e-32
LR134341.1\|VEF93463.1\|781894_782188_-\|CRISPR-associated-protein-cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.65078e-34
LR134341.1\|VEF93465.1\|783222_783891_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	2.40049e-29
LR134341.1\|VEF93468.1\|786630_787368_-\|CRISPR-associated-protein	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	8.50629e-95
LR134341.1\|VEF93460.1\|777223_778258_-\|Sip11	gnl\|CDD\|270264	cd13546, PBP2_BitB, Substrate binding domain of a putative iron transporter BitB, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.6649e-107
LR134341.1\|VEF93472.1\|794294_794861_-\|shikimate-kinase	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	0.00196923
LR134341.1\|VEF93453.1\|770060_770777_-\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	4.27549e-89
LR134341.1\|VEF93466.1\|783892_784741_-\|CRISPR-associated-protein	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.88442e-136
LR134341.1\|VEF93455.1\|771895_772816_-\|CorA-like-Mg2+-transporter-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.15088e-70
LR134341.1\|VEF93467.1\|784744_786631_-\|CRISPR-associated-protein	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	3.30542e-118
LR134341.1\|VEF93469.1\|787882_790288_-\|CRISPR-associated-helicase	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	9.16456e-83
LR134341.1\|VEF93458.1\|774469_776134_-\|ABC-transporter,-permease-protein	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	2.2856e-106
LR134341.1\|VEF93456.1\|772879_773839_-\|oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.85701e-56
LR134341.1\|VEF93454.1\|770804_771884_-\|cytoplasmic-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.15187e-20
LR134341.1\|VEF93471.1\|791572_794224_-\|valyl-tRNA-synthetase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
LR134341.1\|VEF93461.1\|778333_779101_-\|transcriptional-regulator,-AraC-family	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.03089e-47
LR134341.1\|VEF93459.1\|776134_777214_-\|ABC-transporter,-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	2.51607e-152
LR134341.1\|VEF93470.1\|790927_791131_-\|IS200-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	7.72145e-21
LR134341.1\|VEF93464.1\|782197_783223_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	4.87605e-179

>LR134341.1|VEF93462.1|779088_780759_-|histidine-kinase
MVNMEREVGLTFREKLRLEVFAGFKKTALVIGLSYVVVLTLFIVSVQYSQLAGGTNDIVSYFNTVHWKSDRLFAKLEEKGLNQFLSGHLSEREMFRKVYQESTRLPFRSAISIYNPRGTLLLSTRLPNRNGLQDDAFVKIALPNINRETEDRLMKDYQGNPFLLKMKAIWSKGVKIGYLVLYIDGNDFESGLKIGATQYVIADRFNHLFTSNSLQDRTLSWQKINANQLKKWMTISEGNLILHQWKSLSQELFLYTSIVVLPLSYLLIFTGFFVLGIMSLLIALARGLSERIASHSSDSIALLVQDLEKIVNGYQDKVVVRTEDEFGYLAQKINSLLNTLQRLFHQTLALEQEKTTVERKLLEAQFNPHFLYNSLESIKILIDFNPHKAQAIILALNRVLRYSITSQEEYATLASDFDILEDFLAVNQVRFEDFSFLLSYPEDLQGLRVPKLFLLPLVENALKYGMQSRHDLAIKVELQMTDRYVHIYVLDNGPGFSQSFKDDFARYFKAGQTEHGLVNSYSRLVMLYPSATIELCQVDTLNGVLLQFERKQACYG
>LR134341.1|VEF93461.1|778333_779101_-|transcriptional-regulator,-AraC-family
MLRMIIVEDEHLIRNWLSQVIDYKQMGIELLACARDGQEGIEVIEGYRPDIVLTDIMMPRKTAFDMFEATRRIPYQKIILSSFSDFQNAKKAMRYGVYNFLEKPLDKEELRDCLWQICLDLKTEATSLASEEGLSKQFPTIDLPVIDGNYLSAQVISYLHHHYNQTLSTERIAHHFGYSESYLYKKVKEELGITIKDYLNRYRMRRAIKLILEEPHLLVYQVSEAVGYSDYNYFGKVFRRYTGLTFTEFKENFTH
>LR134341.1|VEF93460.1|777223_778258_-|Sip11
MRKKTLTVLMASVALLGLAACGSKAGNKKEAKGSDKLVVYSPNSEGLINATIPAFEEKYGIKVELIQAGTGELFKKVESEASKPVADVVFGGSYTQYAQHPELFEKYTAKDNDKVIKDYQNTTGYSTPYTLDGSVLIVNPDLTKGMKIKGYKDLLNPELKGKIATADPANSSSAFAQLTNMLKATGGYDKKAAWDYVKDLFTLVDGKINSSSSNVYKSVADGEMAVGLSYEDPSVKLLNDGANIKVIYPEEGSVFLPASAAIIKNAPNKSNAKKFIDFIVSKEAQNALGTETTNRPVRNDVKVSKNMKSLKDIKTITEDYDYVIKHKAEIVKHYNDIFVDIQSK
>LR134341.1|VEF93459.1|776134_777214_-|ABC-transporter,-ATP-binding-protein
MSQITIKNAKKVYHDTPVIEDLNVVIPDGSLFTLLGPSGCGKTTLLRMIAGFNSIEGGDFYFGEDRINQMEPSHRNIGMVFQNYAIFPHLSVKDNVAFGLKQRKLSKTEIERRVDKYLKLMQIDQFKDRKPENLSGGQQQRVALARALAISPDVLLMDEPLSNLDAKLRIDMRQAIKEIQKEVGITTVYVTHDQEEAMAISDQIAVMYLGEIQQIGKPKELYHRPSNEFVATFIGRTNMLDAELIHQDAQAYLQFKDGYTISFPSLNHLRDQAVRVSIRPEEFIRQSDGPIEATIKDSTYLGLNTEYIVETPFASRLQVTEESTLEEDFGAGNRIRLTINAQKINVFSADGKVNLLGVE
>LR134341.1|VEF93458.1|774469_776134_-|ABC-transporter,-permease-protein
MIKNLQKMNIWILSSIIIFISYLLFLIYPIVTILKQALFVDGQLSIQHFLTFFSKDYYFETLLNSFKVSVMATLLSLVVGTLLAYCFAMFRFKGKKYLQILVIIASMSAPFVGAYSWILLLGRNGVITKWLQTSFGFPKIDIYGFAGIVLVFTLQLFPLVFLYVSGALKSMDNSLLEAAESMGVKGSKRLTKIVLPLLVPTLLAAALLVFMRAFSDFGTPMLIGEGYRTFPVLVYSQFISEVGGNSAFASALAIIAITIALIIFLVQKYLAQKHSFSMSSLHPIEAKSVKGWQKLLVYVWVYGVIGLSVLPQTYLIYTSFLKTSGMIFVPGYSFNSYVQAFNRMGTSILNTLRIPLMALGLVLVFATFISYLSVRKRNAFTSLIDSMSMVPYIVPGTVMGIAFITAFNTGIAGSGFLAIIGTSLVMVISLAVRRLPYTIRSSVAALHQISPSIEEAASSLGSSRLNTFVKITIPMMLSGIVSGAILSWITMISELSTSILLYNINTKTMTVAIYTEVLRGNYGIAAALSTILTTFTVLSLLLFMKVAKSDSITM
>LR134341.1|VEF93457.1|774057_774255_-|Uncharacterised-protein
MSELTSICLSDDLNEQLNFWTNTYHISKAEFINQIIAEKLDSLYAIQEADLAMRDWIKEHQNTYF
>LR134341.1|VEF93456.1|772879_773839_-|oxidoreductase
MVIVRYGVVSTAQVAPRFIEGVRLAGNGEIVAVSSRSFEKARTFAAQYHIPKAYGSLSEMIADPDIDIIYVPTINKDHYNCAKKALQAGKHVLVEKPFTLTYAEARELFNLAYRKKLFLMEAQKSVFIPLTDIIKKTIQSGELGDILSVSSTTAYPNIDHIAWFRDLEAGGGTAHFMAPYAFSYLQYLFDCPIEKAGGIANFLEGESDSQSKILLQMGNGVMVDIFLTTKLKLKHQMTIRGTKGTLEIPSFWKSTMATLTYEDGSRRLLEAPMDSDFASEAYHVSQMVQEGATTSPIMKPEITLLTIKIIEELYKSWGK
>LR134341.1|VEF93455.1|771895_772816_-|CorA-like-Mg2+-transporter-protein
MPGETKTQDLFKVINVDHLSTDDKQLLMSLGDLGQDVLDYAQDSNETAFVKEQDGWLVLVYQLLEDKIVSLKAGNIPKIMPMTFVVSSQSLLILETDETTQLLAKVIDRVNLSQEPKEIMFQLLTLFTKSYFTEVEAMGKERDYLMNQLRQRATKKNLTELANLQSGSVYVMMGSQQNGDMLADFQELASYDSFSERVKAKLRDTVIEVKQLSNMCSLHTRILEQLASSYNNVLSNRLNDNVTSLTIFTIGLTVITTVTSFYGMNVKLPFAEVDIVWLLILIITTIIALILMHFLRRFVNDGHRHL
>LR134341.1|VEF93454.1|770804_771884_-|cytoplasmic-protein
MTIEENVFRKRQIQLDRLVPFGFNQDQDGSFSYHADIMGGAFTVQVVVEAEGQLSSRVIDNDMKEDYLAIHVEKMVPSYVGQVQTAYQAVLEEISEACCILFPFQSDQMNRLNQRLVDNFSDSLDQPFDNHFDTYSYRVGGKWYAVIFPLALNKLEGIAEDYKNQTAEVINLKVKPRELDTLLSQNGIYPAYHMSKKSWISIILDDSLSDEVIWKLILASRALVESPLLKRFKGPDFWIIPANLNYYDIDSEFAASTDILWTQKASIKIGDYVFIYITAPTKAIRYVCRVLEVNIPNEDFRPRKDIKTLMHLQLIEKFADDQLPLEVLQEHGVKSVRGPRRLTPQFIAFLQEKGYLKED
>LR134341.1|VEF93453.1|770060_770777_-|B3/4-domain-containing-protein
MSRFIVDQSFWDLFPEAQLGVVLLHNYQSSGESSKEIKMILRESQSLAEQYLTESNFADNEVIRTYRNAYQQFKTKKGARSSIEALLKRVSKGNQIPSINPLVDIYNAASLRFALPVGAEDLDSFVGDLRLTITDGNDSFYLIGDENDSPTLPNELCYKDDIGAVCRCLNWRDGARTMITANTKNAFLVIELLDRGRLDQLIEALNFIEGHAKLQLGAEAEKYILTKENTCVDLGKKI
>LR134341.1|VEF93463.1|781894_782188_-|CRISPR-associated-protein-cas2
MMVLITYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVSPADFVEIKDKLTKIIDMESDSVRFYRLGKHWQKRVEILGRDVSYDPDMGLLLL
>LR134341.1|VEF93464.1|782197_783223_-|CRISPR-associated-protein-Cas1
MKKLLNTLYLTQDNFYLTRERDNIVIKQDSKVISRFPYRIIDGIVCFSYLGASPSLIELCSENNINLSFHTPQGRFCGRFVGSTNGNVLLRREHYRIADNDASLEYAKRFMLAKISNARKYLVRFRRDHRDRVNSQLFEEINTELIWALEHIPLASDKGTLLGIEGQAANHYFRAFNDLVLSDKDTFYFYGRTRRPPQDCINALLSFGYSLLTYECQSALEAVGLDSYVGFYHTDRPGRASLALDLVEEFRSFIVDRFIFSLINKGRLTKKHFEIKETGSVLLTEKGRAIFLEAWQKRKHVEVVHPFTKEKVKMMLLPYIQAQLLAKSIRGELDSYPPFLI
>LR134341.1|VEF93465.1|783222_783891_-|CRISPR-associated-protein-Cas4
MVYAEEDYLMLSGIQHFQFCKRQWALIHIEQQWSDNEATAHGQTLHQKADNPFIKEKRKDTIISRAIHISSKNLGLYGILDVLEFHRDSSGIPLEGRNGLWIPLVVEYKRGKPKKDTRDIVQLVAQVICLEETLGCYIDKGYLYYHSVNQKVEVDITEDLRREVHQLADQMHDYYNHKVVEKAAYFKNCTLCSLVDICMPRLSKKTPSVNNYINNSIISEVI
>LR134341.1|VEF93466.1|783892_784741_-|CRISPR-associated-protein
MLEQKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKLRNRLQDMGQPIFVQASERIEDEFHSLEKRFSNQFTAKDKDEDIAEKANELWFDVRSFGQVFTYLKKSIGVRGPVSISMAKTFDPIVISSLQITRSTNGMEPKGDSSRSSDTMGTKHFVDYGVYLVKGSINAHFAEKTGFSEEDAELIKQALMSLFENDTSSARPEGSMRVRQLFWFKHSSKLGNVSSARIYDLLVVDKSKKDKTSYEDYHIRLDEEKLAEYQAKGLEVEILEGL
>LR134341.1|VEF93467.1|784744_786631_-|CRISPR-associated-protein
MDFFTSLLKAYEGAEKEDYVDNPAKSGPVLLPIYHTSLKSNGKNVITVKLDCYGQLLSADFLGDKEVIVFPITSDSVARAGKNPTPHPLVDKFSYFVSKVNQDQYNTYHKQLDNWVTACEDGQVKDYLKLIQHAILQEDFSEKIINSLMSEPYQRNGLVLTYDLEAKKSKTMDLSACFLEFSIVDFIGYKTISVTNFTELHQAYIDYIESHQENLILCNISGRKEVLATKHRGLIGNAKLISVSNNNEAYKGRFKERNDVFSVGNQTSEKIHLMAKYFLENENTHTWLGSGQHLINWFSDDLINESQLTVTNPVTSLFNYEDDANNKTEFTVSQKDNDISNSFIRGVKKFSDASSYYAAILNKTNDGRIALKYFRQLQASQLLKNLEQWQACYSWERRRKDGTYNDYTPSLMQIILAAYGVDRERFIELDNDHFKSEQFQKLLTNLIDGKPLPSSIVKKLEENIKQRQKYSKHWYQVQQVSLGILHKQNGEELSPMLDHTNQNRSYLFGRLLAIFELIETLRYKLDNSDSGRITNAERYWTAYTGQPTKLMMLLENKIKPYEETLKLNSRGPWSKLNKEKEEIMQLLTPLLETESMEKPLDYQFIFGYYAEKKFYYTKQEIVTNEGEE
>LR134341.1|VEF93468.1|786630_787368_-|CRISPR-associated-protein
MFRSRNFYFRLRGNLALFTNPATKGGGERSSYSVPTRQALQGIVDAIYFKPTITNVVTEVKVCNQIQTELHGVRALLANYRSDLSYVSYLSDVEYLVKFHFIWNEDRPDLLYDRLPNKHEAIMERSIRKGGRRDIFLGTRECLGLVDDICQEDYEQAEVAYAGQTIDFGMMFHSFKYPKDKSESLKSYFAHIVMENGCIRFKEQKDCEIMNTLSSYAFKAPNQIKSADEEFAIYQADEESEKGGN
>LR134341.1|VEF93469.1|787882_790288_-|CRISPR-associated-helicase
MIMGHYDANTGRKQPLEEHLFNVAVDASRRSSAIKQNDVLFLLGLFHDLGKAHPDFQDKLLNHPNHHVDHSSAGAYYLLLKIQQYLIPKGIPKKSCQLFSEVVGYVISSHHGMYDLYDKEANRSQFNRLMERLTKFLEKVEFDKTIQPFAANLELKLSVYGYEHLEDLIVKSYANFKNALDKLPCKDDTERDFYIGAFVRLYLSFLKNADILDTVNAYEEVIIPSNEEKNQERRDNYLQSVEDLYRKFEKANNDLNQVRTMIAERVKERGQKDTAGIYRLNLPTGAGKTKASLRYAVQQMACQDRKRFYYVTAFLSVLEQNAKDIKAIIGEDGVLEHHSNVVREKEFQDFNEETYDEVMQEYLLDSWDSPVVLTTMVQFFQTLFKIKSANIRRFSNLANSVMVLDEVQSLPIEVTSLFNLTMNFMSRVMNTTIILCTATQPAYDYDSLVHQLVYGGEVTEQADIVSLMEEERVIFERTELKKLKEDNSKVTLSEVAEFVLEQEESVLVILNTKPSVYQLHQLLSEQTNRPLYQLSTNMCPQHRLDTISEIKKLLKEDIPLICVSTQLIEAGVDVDFARVIRSYAGLDSIVQASGRCNREGKRDLGQVILVNISNEDENISRLTEIKKKKSVTEDILCRQSSPIDVSVLNDEFFKRYYENNTKDMDYPLGDNQTAYDFLSYNHYAGFQLKGMLRQAFKTAGQKIDLIKDESIGVFVPYGNSIAMLEDFETFLTDHPYPNFEDYTYIKERMKNLQLYTVNAREDSSFLKQAKSYLGGQIWILPQKFYDDKMGIKKEADALLIF
>LR134341.1|VEF93470.1|790927_791131_-|IS200-transposase
MPDYVHMLVSIPPRISVSSFIGYLKGKSALMMFDKHANLKYKFGNRHFWAEGYYVSKVGLNEATIKK
>LR134341.1|VEF93471.1|791572_794224_-|valyl-tRNA-synthetase
MSKELSPKYNPTEVEAGRYQKWLDQEVFKPSGDKKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGITRYDLGREKFLEKVWEWKDEYAATIKEQWGKMGISVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMTYMLEDGSRGLQVATTRPETMFGDVAVAVNPEDPRYKDLIGENVVLPIVNKLIPIVADEHADPEFGTGVVKITPAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKATVAKLKELGALVNIEERVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMANQDTENRVDFYPPRFNDTFMSWMENVHDWVISRQLWWGHQIPAWYNAEGDIYVGEEAPEGDGWKQDEDVLDTWFSSALWPFSTMGWPDTEAEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTNERPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVVEKYGADALRWFLSNGSAPGQDVRFSYEKMDAAWNFINKIWNISRYILMNNEGLTLAEAESNVAKVAASEAGNVTDRWILHNLNETIVKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSNNEEEKVMTRSVLLYTLDKILRLLHPIMPFVTEEIYAQYADGSIVTAVYPVADAAFENETAHRGVESLKDLIRAVRNARAEVNVAPSKVITILIKTSDKELEGFFKTNENYIRRFTNPEKLEISADLQVPEMAMTSIITGAEIYLPLADLLNVDEELARLDKELAKWQKELDMVGKKLSNERFVANAKPDVVQKERDKQADYQAKFDATEERITEMKKLVK
>LR134341.1|VEF93472.1|794294_794861_-|shikimate-kinase
MNLIFIGAQASGKMTIGQEVAKLTEMTLFHNHETIDFVLRFMPWSKDATDLITKIRFDFFETFAKIGRPMIFTIVIDFGDPNEVAFLDALQSTFEGNDQEVLFVELETSLEERLVRNKTENRLKHKPLKRDIAWSEKDILSTMGYVTFNSKEAPEKMHHYCKINNTHKSAKEVAKEIVAVMKQIEKEK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR134341_1	1.9\|389303\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389303-389332	30	LR134341.1	1895356-1895385	0	1.0

1. spacer 1.9|389303|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to position: 1895356-1895385, mismatch: 0, identity: 1.0

aaaaaattgtacctgcaatggaaagacgaa	CRISPR spacer
aaaaaattgtacctgcaatggaaagacgaa	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448701	Streptococcus phage Javan197, complete genome	30663-30692	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	NC_009018	Streptococcus phage phi3396, complete genome	31893-31922	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448679	Streptococcus phage Javan137, complete genome	32068-32097	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448690	Streptococcus phage Javan169, complete genome	36470-36499	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448864	Streptococcus phage Javan180, complete genome	24421-24450	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448682	Streptococcus phage Javan143, complete genome	33775-33804	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448686	Streptococcus phage Javan157, complete genome	34991-35020	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448854	Streptococcus phage Javan146, complete genome	36472-36501	1	0.967
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448747	Streptococcus phage Javan385, complete genome	41139-41168	1	0.967
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448675	Streptococcus phage Javan129, complete genome	36813-36842	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448960	Streptococcus phage Javan492, complete genome	33511-33540	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448973	Streptococcus phage Javan522, complete genome	34924-34953	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448858	Streptococcus phage Javan166, complete genome	39773-39802	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448762	Streptococcus phage Javan447, complete genome	33644-33673	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448862	Streptococcus phage Javan178, complete genome	31852-31881	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448769	Streptococcus phage Javan471, complete genome	29465-29494	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448848	Streptococcus phage Javan126, complete genome	30682-30711	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448857	Streptococcus phage Javan164, complete genome	30682-30711	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448677	Streptococcus phage Javan133, complete genome	31673-31702	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448684	Streptococcus phage Javan151, complete genome	29465-29494	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448869	Streptococcus phage Javan190, complete genome	30917-30946	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448778	Streptococcus phage Javan493, complete genome	34564-34593	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	NC_009819	Streptococcus phage P9, complete genome	33464-33493	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448850	Streptococcus phage Javan132, complete genome	35913-35942	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448870	Streptococcus phage Javan192, complete genome	30917-30946	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448975	Streptococcus phage Javan526, complete genome	35346-35375	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448782	Streptococcus phage Javan501, complete genome	37704-37733	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448673	Streptococcus phage Javan119, complete genome	40031-40060	2	0.933
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448962	Streptococcus phage Javan496, complete genome	30229-30258	2	0.933
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448952	Streptococcus phage Javan472, complete genome	33911-33940	3	0.9
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448794	Streptococcus phage Javan525, complete genome	33455-33484	3	0.9
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448793	Streptococcus phage Javan523, complete genome	34972-35001	3	0.9
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448765	Streptococcus phage Javan459, complete genome	33453-33482	3	0.9
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448852	Streptococcus phage Javan140, complete genome	33899-33928	3	0.9
LR134341_1	1.5\|389039\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389039-389068	30	MK448858	Streptococcus phage Javan166, complete genome	16975-17004	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448973	Streptococcus phage Javan522, complete genome	39060-39089	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448965	Streptococcus phage Javan506, complete genome	39312-39341	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448959	Streptococcus phage Javan488, complete genome	38914-38943	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448778	Streptococcus phage Javan493, complete genome	38703-38732	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448949	Streptococcus phage Javan460, complete genome	39710-39739	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448783	Streptococcus phage Javan503, complete genome	35636-35665	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448975	Streptococcus phage Javan526, complete genome	39494-39523	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448764	Streptococcus phage Javan457, complete genome	30597-30626	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448782	Streptococcus phage Javan501, complete genome	41844-41873	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448791	Streptococcus phage Javan517, complete genome	40571-40600	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	NC_004587	Streptococcus prophage 315.4, complete genome	40147-40176	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	41417-41446	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448962	Streptococcus phage Javan496, complete genome	31418-31447	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448977	Streptococcus phage Javan530, complete genome	40052-40081	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448788	Streptococcus phage Javan511, complete genome	40052-40081	3	0.9
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448950	Streptococcus phage Javan464, complete genome	40776-40805	3	0.9
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448796	Streptococcus phage Javan53, complete genome	42329-42358	4	0.867
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448951	Streptococcus phage Javan470, complete genome	33709-33738	4	0.867
LR134341_1	1.5\|389039\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389039-389068	30	MK448854	Streptococcus phage Javan146, complete genome	16460-16489	4	0.867
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448820	Streptococcus phage Javan617, complete genome	33199-33228	4	0.867
LR134341_1	1.9\|389303\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389303-389332	30	MN905160	Pseudomonas phage PE09, complete genome	86783-86812	4	0.867
LR134341_1	1.2\|388842\|29\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388842-388870	29	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	647323-647351	5	0.828
LR134341_1	1.2\|388842\|29\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388842-388870	29	MK125140	Enterococcus phage Nonaheksakonda, complete genome	33896-33924	5	0.828
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448946	Streptococcus phage Javan456, complete genome	38048-38077	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448871	Streptococcus phage Javan196, complete genome	34496-34525	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	NC_004585	Streptococcus prophage 315.2, complete genome	34236-34265	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448961	Streptococcus phage Javan494, complete genome	33442-33471	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448966	Streptococcus phage Javan508, complete genome	34091-34120	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448697	Streptococcus phage Javan185, complete genome	34496-34525	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448968	Streptococcus phage Javan512, complete genome	33280-33309	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448959	Streptococcus phage Javan488, complete genome	34778-34807	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	NC_004587	Streptococcus prophage 315.4, complete genome	33356-33385	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448693	Streptococcus phage Javan177, complete genome	34496-34525	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	34626-34655	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448772	Streptococcus phage Javan483, complete genome	34331-34360	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448941	Streptococcus phage Javan446, complete genome	36161-36190	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448696	Streptococcus phage Javan183, complete genome	34496-34525	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448977	Streptococcus phage Javan530, complete genome	33261-33290	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448797	Streptococcus phage Javan531, complete genome	33280-33309	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448949	Streptococcus phage Javan460, complete genome	35577-35606	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448958	Streptococcus phage Javan486, complete genome	33694-33723	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448868	Streptococcus phage Javan188, complete genome	34497-34526	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448866	Streptococcus phage Javan184, complete genome	34496-34525	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448845	Streptococcus phage Javan118, complete genome	30812-30841	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448788	Streptococcus phage Javan511, complete genome	33261-33290	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448954	Streptococcus phage Javan476, complete genome	33354-33383	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448957	Streptococcus phage Javan484, complete genome	38745-38774	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448699	Streptococcus phage Javan189, complete genome	34496-34525	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	NC_004589	Streptococcus prophage 315.6, complete genome	33377-33406	5	0.833
LR134341_1	1.3\|388907\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388907-388936	30	MK448867	Streptococcus phage Javan186, complete genome	34496-34525	5	0.833
LR134341_1	1.6\|389105\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389105-389134	30	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	218362-218391	5	0.833
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	NC_004584	Streptococcus prophage 315.1, complete genome	37195-37224	5	0.833
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448785	Streptococcus phage Javan507, complete genome	37090-37119	5	0.833
LR134341_1	1.5\|389039\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389039-389068	30	MK448851	Streptococcus phage Javan14, complete genome	16242-16271	6	0.8
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	DQ198146	Bacteriophage 700P1 putative tape measure protein, hypothetical phage-associated protein, putative tape measure protein, hypothetical phage-associated protein, putative tail components, putative tail-host specificity protein, putative structual protein, hypothetical phage-associated proteins, and lysin genes, complete cds	11332-11361	6	0.8
LR134341_1	1.1\|388776\|30\|LR134341\|CRISPRCasFinder,CRT	388776-388805	30	AP013399	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C42	10889-10918	7	0.767
LR134341_1	1.1\|388776\|30\|LR134341\|CRISPRCasFinder,CRT	388776-388805	30	NC_032098	Enterobacter cloacae strain EC4365 plasmid pEC4365, complete sequence	909-938	7	0.767
LR134341_1	1.1\|388776\|30\|LR134341\|CRISPRCasFinder,CRT	388776-388805	30	NZ_CP032537	Bacillus megaterium NCT-2 plasmid pNCT2_9, complete sequence	1693-1722	7	0.767
LR134341_1	1.2\|388842\|29\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	388842-388870	29	MN694447	Marine virus AFVG_250M387, complete genome	54269-54297	7	0.759
LR134341_1	1.1\|388776\|30\|LR134341\|CRISPRCasFinder,CRT	388776-388805	30	MK449004	Streptococcus phage Javan68, complete genome	24051-24080	8	0.733
LR134341_1	1.5\|389039\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389039-389068	30	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1286081-1286110	8	0.733
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448729	Streptococcus phage Javan31, complete genome	38081-38110	8	0.733
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448850	Streptococcus phage Javan132, complete genome	42772-42801	8	0.733
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448837	Streptococcus phage Javan10, complete genome	35872-35901	8	0.733
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448691	Streptococcus phage Javan17, complete genome	38081-38110	8	0.733
LR134341_1	1.8\|389237\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389237-389266	30	MK448948	Streptococcus phage Javan46, complete genome	38024-38053	8	0.733
LR134341_1	1.9\|389303\|30\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	389303-389332	30	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	65515-65544	8	0.733
LR134341_3	3.3\|781087\|34\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	781087-781120	34	NZ_KX258624	Bacillus thuringiensis strain INTA Fr7-4 plasmid pFR260, complete sequence	173442-173475	8	0.765
LR134341_3	3.7\|781353\|35\|LR134341\|CRISPRCasFinder,CRT,PILER-CR	781353-781387	35	NC_009931	Acaryochloris marina MBIC11017 plasmid pREB6, complete sequence	151901-151935	9	0.743

1. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448701 (Streptococcus phage Javan197, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgggtaaactcagcacgtaag	Protospacer
***********.******************

2. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcggcacgtaag	Protospacer
********************.*********

3. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcggcacgtaag	Protospacer
********************.*********

4. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcggcacgtaag	Protospacer
********************.*********

5. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcagcccgtaag	Protospacer
*********************** ******

6. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448682 (Streptococcus phage Javan143, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcggcacgtaag	Protospacer
********************.*********

7. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcggcacgtaag	Protospacer
********************.*********

8. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 1, identity: 0.967

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgagtaaactcggcacgtaag	Protospacer
********************.*********

9. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448747 (Streptococcus phage Javan385, complete genome) position: , mismatch: 1, identity: 0.967

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagttaattctgggcggttttttttgtg	Protospacer
************************* ****

10. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcggcacgtaag	Protospacer
* ******************.*********

11. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaag	Protospacer
**.**.************************

12. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaag	Protospacer
**.**.************************

13. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcacgcaag	Protospacer
* ************************.***

14. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaag	Protospacer
**.**.************************

15. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgggtaaactcagcacgcaag	Protospacer
***********.**************.***

16. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcacgcaag	Protospacer
* ************************.***

17. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448848 (Streptococcus phage Javan126, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcacgcaag	Protospacer
* ************************.***

18. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448857 (Streptococcus phage Javan164, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcacgcaag	Protospacer
* ************************.***

19. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448677 (Streptococcus phage Javan133, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcacgcaag	Protospacer
* ************************.***

20. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcacgcaag	Protospacer
* ************************.***

21. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448869 (Streptococcus phage Javan190, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgggtaaactcagcccgtaag	Protospacer
***********.*********** ******

22. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaag	Protospacer
**.**.************************

23. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgggtaaactcagcacgcaag	Protospacer
***********.**************.***

24. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcggcacgtaag	Protospacer
* ******************.*********

25. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448870 (Streptococcus phage Javan192, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgggtaaactcagcccgtaag	Protospacer
***********.*********** ******

26. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaag	Protospacer
**.**.************************

27. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaag	Protospacer
**.**.************************

28. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.933

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tggttgctacgggtaaactcagcacgcaag	Protospacer
***********.**************.***

29. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 2, identity: 0.933

ctcagttaa-ttctgggcggttttttgtgtg	CRISPR spacer
-tcagataatttctgggcggttttttgtgtg	Protospacer
 **** *** *********************

30. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 3, identity: 0.9

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaaa	Protospacer
**.**.***********************.

31. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 3, identity: 0.9

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaaa	Protospacer
**.**.***********************.

32. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 3, identity: 0.9

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaaa	Protospacer
**.**.***********************.

33. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 3, identity: 0.9

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgattactacgagtaaactcagcacgtaaa	Protospacer
**.**.***********************.

34. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448852 (Streptococcus phage Javan140, complete genome) position: , mismatch: 3, identity: 0.9

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcgttgctacgagtaaactcagcatgcaag	Protospacer
* **********************.*.***

35. spacer 1.5|389039|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 3, identity: 0.9

gttctgccgatacacgattgagcgccagct	CRISPR spacer
gttctgccgatacacgattaagcgctagtt	Protospacer
*******************.*****.**.*

36. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

37. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

38. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

39. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

40. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

41. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448783 (Streptococcus phage Javan503, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgtt	Protospacer
***** * *********************

42. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

43. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgtt	Protospacer
***** * *********************

44. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagattattctgggcggttttttgtgta	Protospacer
***** * *********************.

45. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

46. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

47. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

48. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

49. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

50. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

51. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 3, identity: 0.9

ctcagttaattctgggcggttttttgtgtg-	CRISPR spacer
ctcagataattctgggcgg-tttttgtgttt	Protospacer
***** ************* *********

52. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 4, identity: 0.867

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgataactacgagtaaactcagcacgtaat	Protospacer
**.* .***********************

53. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 4, identity: 0.867

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tcattactacgagtaaactcagcacgcaag	Protospacer
* .**.********************.***

54. spacer 1.5|389039|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 4, identity: 0.867

gttctgccgatacacgattgagcgccagct	CRISPR spacer
gttctgccgatacacgattaagcgctagtc	Protospacer
*******************.*****.**..

55. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448820 (Streptococcus phage Javan617, complete genome) position: , mismatch: 4, identity: 0.867

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
ctcagttaattctgggcggtttttttattt	Protospacer
*************************   *

56. spacer 1.9|389303|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MN905160 (Pseudomonas phage PE09, complete genome) position: , mismatch: 4, identity: 0.867

aaaaaattg--tacctgcaatggaaagacgaa	CRISPR spacer
--aagattgattaccagcaatggaaagacgaa	Protospacer
  **.****  **** ****************

57. spacer 1.2|388842|29|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 5, identity: 0.828

ttactcattaagtatatcatgaaaaaaga	CRISPR spacer
ttttttattacatatatcatgaaaaaaga	Protospacer
** .*.**** .*****************

58. spacer 1.2|388842|29|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK125140 (Enterococcus phage Nonaheksakonda, complete genome) position: , mismatch: 5, identity: 0.828

ttactcattaagtatatcatgaaaaaaga	CRISPR spacer
ttatgaattaagtatatcatgagaaaaaa	Protospacer
***.  ****************.****.*

59. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

60. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

61. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

62. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448961 (Streptococcus phage Javan494, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

63. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

64. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

65. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

66. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

67. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

68. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

69. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

70. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

71. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448941 (Streptococcus phage Javan446, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

72. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

73. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

74. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

75. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

76. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

77. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

78. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

79. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatgggagcgagtaaactcagcacgtaag	Protospacer
**.* *  .*********************

80. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

81. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

82. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

83. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

84. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

85. spacer 1.3|388907|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 5, identity: 0.833

tggttgctacgagtaaactcagcacgtaag	CRISPR spacer
tgatttgagcgagtaaactcagcacgtaag	Protospacer
**.**   .*********************

86. spacer 1.6|389105|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.833

tatttatctttttaccaagctgatttacta	CRISPR spacer
catttaactttttaccaagctgatgttcaa	Protospacer
.***** ***************** * * *

87. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 5, identity: 0.833

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
cagattaatttctgggcggttttttgtgtg	Protospacer
*  * * * *********************

88. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 5, identity: 0.833

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
cagattaatttctgggcggttttttgtgtg	Protospacer
*  * * * *********************

89. spacer 1.5|389039|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 6, identity: 0.8

gttctgccgatacacgattgagcgccagct	CRISPR spacer
gttccgccgatacacgattaagcgctaatc	Protospacer
****.**************.*****.*...

90. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to DQ198146 (Bacteriophage 700P1 putative tape measure protein, hypothetical phage-associated protein, putative tape measure protein, hypothetical phage-associated protein, putative tail components, putative tail-host specificity protein, putative structual protein, hypothetical phage-associated proteins, and lysin genes, complete cds) position: , mismatch: 6, identity: 0.8

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
cagattaatttctgggcggttttttttgtg	Protospacer
*  * * * **************** ****

91. spacer 1.1|388776|30|LR134341|CRISPRCasFinder,CRT matches to AP013399 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C42) position: , mismatch: 7, identity: 0.767

actccagttccagatccaactccagatcca	CRISPR spacer
ttaccagttccagttccaaatccagatgta	Protospacer
 . ********** ***** ******* .*

92. spacer 1.1|388776|30|LR134341|CRISPRCasFinder,CRT matches to NC_032098 (Enterobacter cloacae strain EC4365 plasmid pEC4365, complete sequence) position: , mismatch: 7, identity: 0.767

actccagttccagatccaactccagatcca	CRISPR spacer
actccaagtccagatccaactccggcagcg	Protospacer
******. ***************.*   *.

93. spacer 1.1|388776|30|LR134341|CRISPRCasFinder,CRT matches to NZ_CP032537 (Bacillus megaterium NCT-2 plasmid pNCT2_9, complete sequence) position: , mismatch: 7, identity: 0.767

actccagttccagatccaactccagatcca	CRISPR spacer
aaagcaaaaccagatccaaatccagatcca	Protospacer
*   **.  ********** **********

94. spacer 1.2|388842|29|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MN694447 (Marine virus AFVG_250M387, complete genome) position: , mismatch: 7, identity: 0.759

ttactcattaagtatatcatgaaaaaaga	CRISPR spacer
aactttattaagtataccaagaaaaaaga	Protospacer
   .*.**********.** *********

95. spacer 1.1|388776|30|LR134341|CRISPRCasFinder,CRT matches to MK449004 (Streptococcus phage Javan68, complete genome) position: , mismatch: 8, identity: 0.733

actccagttccagatccaactccagatcca	CRISPR spacer
gaaggagctccagatccaactccagacaca	Protospacer
.    **.******************. **

96. spacer 1.5|389039|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

gttctgccgatacacgattgagcgccagct	CRISPR spacer
gaatctccgacacacgattgcgcgccagcg	Protospacer
*  .. ****.********* ********

97. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448729 (Streptococcus phage Javan31, complete genome) position: , mismatch: 8, identity: 0.733

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
gctctctaattgagggcggttttttgtgtg	Protospacer
 ..  .*****  *****************

98. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 8, identity: 0.733

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
tcagattatttctaggcggttttttgtgtt	Protospacer
.. ..*** ****.***************

99. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 8, identity: 0.733

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
gctctctaattgagggcggttttttgtgtg	Protospacer
 ..  .*****  *****************

100. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448691 (Streptococcus phage Javan17, complete genome) position: , mismatch: 8, identity: 0.733

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
gctctctaattgagggcggttttttgtgtg	Protospacer
 ..  .*****  *****************

101. spacer 1.8|389237|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to MK448948 (Streptococcus phage Javan46, complete genome) position: , mismatch: 8, identity: 0.733

ctcagttaattctgggcggttttttgtgtg	CRISPR spacer
gctctctaattgagggcggttttttgtgtg	Protospacer
 ..  .*****  *****************

102. spacer 1.9|389303|30|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaattgtacctgcaatggaaagacgaa	CRISPR spacer
ataaaattgtacctggaatagaaagcactg	Protospacer
* ************* ***.*****    .

103. spacer 3.3|781087|34|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX258624 (Bacillus thuringiensis strain INTA Fr7-4 plasmid pFR260, complete sequence) position: , mismatch: 8, identity: 0.765

gtttgac-tactctacatgttaaattacaaaatga	CRISPR spacer
-tctgttatactctacacgttcaattacaaaacta	Protospacer
 *.** . *********.*** **********. *

104. spacer 3.7|781353|35|LR134341|CRISPRCasFinder,CRT,PILER-CR matches to NC_009931 (Acaryochloris marina MBIC11017 plasmid pREB6, complete sequence) position: , mismatch: 9, identity: 0.743

tccaccgcttggtgttgttgcttgcaatgtttttg	CRISPR spacer
tgctgggtttggtgttgctgctggcaatgttttat	Protospacer
* *   *.*********.**** **********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

81627 : 115773

Streptococcus_phage(63.64%)

transposase,integrase,holin

attL 86349:86364|attR 117704:117719

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF92817.1\|81627_82305_+\|transposase	IS1216, transposase	A0A1X9I6C6	Streptococcus_phage	3.0e-123	97.8
VEF92818.1\|82513_82618_+	Uncharacterised protein	NA	NA	NA	NA
VEF92819.1\|82677_82971_+	arsenical resistance operon repressor	A0A2H4PQT4	Staphylococcus_phage	4.9e-14	43.7
VEF92820.1\|82972_83344_+	Arsenical resistance operon trans-acting repressor ArsD	NA	NA	NA	NA
VEF92821.1\|83477_83825_+	arsenical resistance operon repressor	A0A2H4PQT4	Staphylococcus_phage	7.1e-20	43.3
VEF92822.1\|83860_85603_+	sporulation initiation inhibitor protein	NA	NA	NA	NA
VEF92823.1\|85657_85870_+	arsenical-resistance protein	NA	NA	NA	NA
VEF92824.1\|85890_87048_+	coenzyme A disulfide reductase	NA	NA	NA	NA
86349:86364	attL	NA	NA	NA	NA
VEF92825.1\|86995_87793_-\|transposase	transposase	A0A1B1P773	Bacillus_phage	2.5e-60	51.0
VEF92826.1\|87828_88344_-\|transposase	transposase IS861 orfA	NA	NA	NA	NA
VEF92827.1\|88368_89001_+	NAD(FAD)-dependent dehydrogenase	NA	NA	NA	NA
VEF92828.1\|89025_89136_+	Uncharacterised protein	NA	NA	NA	NA
VEF92829.1\|89290_90226_+	multidrug ABC transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	5.2e-25	31.6
VEF92830.1\|90218_90989_+	ABC-2 type transporter	NA	NA	NA	NA
VEF92831.1\|91101_91287_-	antigen-like protein	NA	NA	NA	NA
VEF92832.1\|92034_94152_-	Cadmium-transporting ATPase	E4ZFI9	Streptococcus_phage	3.1e-235	62.7
VEF92833.1\|94148_94508_-	Cadmium efflux system accessory protein	E4ZFI8	Streptococcus_phage	2.7e-22	47.3
VEF92834.1\|95144_95351_+	Uncharacterised protein	A0A1B0RXE8	Streptococcus_phage	1.5e-14	92.5
VEF92835.1\|95328_95724_+\|holin	holin	A0A1B0RXK5	Streptococcus_phage	3.2e-45	99.2
VEF92836.1\|95730_97200_+	N-acetylmuramoyl-L-alanine amidase amiB	A0A1X9I678	Streptococcus_phage	3.5e-262	92.8
VEF92837.1\|97308_97470_+	phage lysin	M1PSL4	Streptococcus_phage	2.3e-18	88.7
VEF92838.1\|97663_98497_+	site-specific recombinase	M1NSJ1	Streptococcus_phage	9.9e-153	96.0
VEF92839.1\|98496_100059_+	site-specific recombinase	Q6DMS5	Streptococcus_phage	3.2e-213	71.7
VEF92840.1\|100132_100747_+	cadmium resistance protein	NA	NA	NA	NA
VEF92841.1\|100759_101098_+	cadmium efflux system accessory protein	E4ZFI8	Streptococcus_phage	1.7e-10	33.3
VEF92842.1\|101522_101969_+	transcriptional repressor CopY	NA	NA	NA	NA
VEF92843.1\|101955_102432_+	cation-transporting ATP-ase, P-type	A0A218MNH6	uncultured_virus	5.3e-26	46.5
VEF92844.1\|102579_102786_+	putative copper-chaperone/transport protein	NA	NA	NA	NA
VEF92845.1\|102924_105012_+	lead, cadmium, zinc and mercury transporting ATPase	E4ZFI9	Streptococcus_phage	1.7e-60	29.9
VEF92846.1\|105185_105782_-	integral membrane protein	NA	NA	NA	NA
VEF92847.1\|105790_106579_+	Uncharacterised protein	NA	NA	NA	NA
VEF92848.1\|106632_106932_-	Uncharacterised protein	Q6DMX6	Streptococcus_phage	5.3e-48	96.0
VEF92849.1\|107235_107502_+	cadmium efflux system accessory protein	E4ZFI8	Streptococcus_phage	1.0e-42	98.9
VEF92850.1\|107494_109624_+	cation transporter E1-E2 family ATPase	E4ZFI9	Streptococcus_phage	0.0e+00	100.0
VEF92851.1\|109898_110240_-\|integrase	integrase catalytic subunit	A0A0C5AEA5	Paenibacillus_phage	1.1e-14	40.6
VEF92852.1\|110623_110731_-	Uncharacterised protein	NA	NA	NA	NA
VEF92853.1\|111053_111416_+	Tn5252, ORF 10 protein	NA	NA	NA	NA
VEF92854.1\|111422_111788_+	Tn5252, ORF 9 protein	NA	NA	NA	NA
VEF92855.1\|111774_113640_+	Tn5252, relaxase	NA	NA	NA	NA
VEF92856.1\|113820_114045_+	Cro/CI family transcriptional regulator	X5JA02	Clostridium_phage	4.4e-07	45.9
VEF92857.1\|114323_114551_+	Domain of uncharacterised function (DUF3173)	NA	NA	NA	NA
VEF92858.1\|114573_115773_+\|integrase	phage integrase family site specific recombinase	A0A1B0T6A8	Bacillus_phage	2.1e-26	28.0
117704:117719	attR	NA	NA	NA	NA

DBSCAN-SWA_2

577906 : 599005

Streptococcus_phage(89.47%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF93285.1\|577906_578596_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.4e-29	34.1
VEF93286.1\|578696_579674_-	two-component system histidine kinase	NA	NA	NA	NA
VEF93287.1\|579666_579966_-	OmpR family two component system phosphate regulon response regulator	NA	NA	NA	NA
VEF93288.1\|580320_580635_+	Bacterial protein of uncharacterised function (DUF961)	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
VEF93289.1\|580653_581037_+	Bacterial protein of uncharacterised function (DUF961)	A0A1S5SF96	Streptococcus_phage	2.3e-64	100.0
VEF93290.1\|581065_582451_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
VEF93291.1\|582628_583834_+	transcriptional regulator protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
VEF93292.1\|583876_584098_+	FIG086557: Conjugation related protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
VEF93293.1\|584214_584712_+	Antirestriction protein	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
VEF93294.1\|584686_585193_+	TcpE family	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
VEF93295.1\|585176_587624_+	Type IV secretory pathway, VirB4 components	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
VEF93296.1\|587626_589804_+	Tn916 ORF15 signal peptide containing protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
VEF93297.1\|589800_590802_+	lipoprotein, NLP/P60 family	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
VEF93298.1\|590798_591731_+	putative conjugative transposon protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
VEF93299.1\|592107_594027_+	tetracycline resistance protein TetM	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
VEF93300.1\|594372_594726_-	anaerobic benzoate catabolism transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
VEF93301.1\|595230_595653_+	RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
VEF93302.1\|595649_595880_+	Helix-turn-helix domain	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
VEF93303.1\|596340_596544_+	Mobile element protein	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
VEF93304.1\|596625_597843_+	Mobile element protein	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
VEF93305.1\|598004_598364_-	two-component response regulator	NA	NA	NA	NA
VEF93306.1\|598593_598686_-	Uncharacterised protein	NA	NA	NA	NA
VEF93307.1\|598783_599005_-	DNA-binding protein	A0A2K5B263	Erysipelothrix_phage	2.2e-11	47.0

DBSCAN-SWA_3

937691 : 999425

Orpheovirus(11.11%)

tRNA,holin,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF93588.1\|937691_938840_+\|holin	Osmotically activated L-carnitine/choline ABC transporter, ATP-binding protein OpuCA	F2Y1V5	Organic_Lake_phycodnavirus	3.9e-14	32.8
VEF93589.1\|938832_939471_+	osmoprotectant ABC transporter	NA	NA	NA	NA
VEF93590.1\|939467_940394_+	ABC transporter	NA	NA	NA	NA
VEF93591.1\|940386_941049_+\|holin	Osmotically activated L-carnitine/choline ABC transporter, permease protein OpuCD	NA	NA	NA	NA
VEF93592.1\|941116_942970_-\|tRNA	prolyl-tRNA synthetase	A0A2K9L297	Tupanvirus	4.8e-06	24.5
VEF93593.1\|942993_944253_-\|protease	pheromone-processing membrane metalloprotease	NA	NA	NA	NA
VEF93594.1\|944289_945084_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
VEF93595.1\|945097_945847_-	UDP pyrophosphate synthase	R9W0U9	Flavobacterium_phage	3.1e-20	39.6
VEF93596.1\|946026_946410_-	preprotein translocase subunit YajC	NA	NA	NA	NA
VEF93597.1\|946480_946840_-	bacterocin transport accessory protein	NA	NA	NA	NA
VEF93598.1\|946905_947904_-	UDP-glucose 4-epimerase	M4QPK0	Synechococcus_phage	4.7e-32	32.7
VEF93599.1\|947903_949382_-	galactose-1-P-uridyl transferase	NA	NA	NA	NA
VEF93600.1\|949394_950558_-	galactokinase	NA	NA	NA	NA
VEF93601.1\|950709_951708_+	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	8.9e-07	23.7
VEF93602.1\|951721_952288_+	acetyltransferase	NA	NA	NA	NA
VEF93603.1\|952347_956238_-	peptidoglycan linked protein (LPXTG motif), pullulanase	NA	NA	NA	NA
VEF93604.1\|956485_958093_-	glucan 1,6-alpha-glucosidase	NA	NA	NA	NA
VEF93605.1\|958183_959317_-	Multiple sugar-binding transport ATP-binding protein msmK	G9BWD6	Planktothrix_phage	7.2e-21	31.8
VEF93606.1\|959457_960306_-	leucine-rich protein Lrp	NA	NA	NA	NA
VEF93607.1\|960327_960771_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
VEF93608.1\|960783_963003_-	GTP diphosphokinase	A0A2I2L310	Orpheovirus	5.6e-09	35.3
VEF93609.1\|963253_965710_+	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase protein	NA	NA	NA	NA
VEF93610.1\|965880_966342_+	flavoprotein	NA	NA	NA	NA
VEF93611.1\|966501_967539_+	M42 gutamyl aminopeptidase	NA	NA	NA	NA
VEF93612.1\|967659_968172_+	putative kinase	NA	NA	NA	NA
VEF93613.1\|968188_969016_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
VEF93614.1\|969061_971248_-	PTS system, glucose-specific II ABC component	A0A2I7SAJ6	Vibrio_phage	2.3e-07	45.8
VEF93615.1\|971475_972252_-	ribosomal RNA small subunit methyltransferase E	NA	NA	NA	NA
VEF93616.1\|972251_973205_-	ribosomal protein L11 methyltransferase	NA	NA	NA	NA
VEF93617.1\|973217_973688_-	Protein of uncharacterised function (DUF3013)	NA	NA	NA	NA
VEF93618.1\|973861_975841_+	amidase family protein	NA	NA	NA	NA
VEF93619.1\|976035_977781_+	para-aminobenzoate synthetase componentI/4-amino-4-deoxychorismate lyase	S4VT78	Pandoravirus	3.7e-32	28.1
VEF93620.1\|977825_978392_+	anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-32	42.9
VEF93621.1\|978422_979694_+	recombination factor protein	A0A127AWE7	Bacillus_phage	7.6e-96	46.8
VEF93622.1\|980182_980731_+\|transposase	ISSag8, transposase	A0A1X9I5T2	Streptococcus_phage	1.5e-72	79.5
VEF93623.1\|980737_980878_-\|transposase	transposase	A0A1X9I5T2	Streptococcus_phage	2.8e-12	76.1
VEF93624.1\|980994_981321_-	Uncharacterised protein	NA	NA	NA	NA
VEF93625.1\|981330_981936_-	hypothetical membrane associated protein	NA	NA	NA	NA
VEF93626.1\|982558_982777_-	Uncharacterised protein	NA	NA	NA	NA
VEF93627.1\|983083_983422_-	Uncharacterised protein	NA	NA	NA	NA
VEF93628.1\|984121_985111_-	UDP-glucose 4-epimerase	A0A1V0SG19	Hokovirus	6.6e-55	38.4
VEF93629.1\|986492_987260_-	HAD-superfamily hydrolase	NA	NA	NA	NA
VEF93630.1\|987673_988315_-	Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2)	G3M9Y6	Bacillus_virus	5.3e-13	25.0
VEF93631.1\|988298_989102_-	Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)	A0A2R8FG22	Brazilian_cedratvirus	1.7e-08	27.7
VEF93632.1\|989113_989935_-	Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)	NA	NA	NA	NA
VEF93633.1\|989931_990909_-	oligopeptide ABC transporter (permease)	NA	NA	NA	NA
VEF93634.1\|991021_992650_-	Glutathione-binding protein gsiB	NA	NA	NA	NA
VEF93635.1\|992985_993558_+	Lysine decarboxylase family	A0A2I2L3F0	Orpheovirus	4.6e-16	30.3
VEF93636.1\|993919_994330_+	Uncharacterised protein	NA	NA	NA	NA
VEF93637.1\|994872_995991_-	transport permease yfiM	NA	NA	NA	NA
VEF93638.1\|995987_997115_-	streptolysin S export transmembrane protein	NA	NA	NA	NA
VEF93639.1\|997123_998047_-	streptolysin S export ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.9e-36	38.3
VEF93640.1\|998067_998757_-	streptolysin S biosynthesis protein SagF	NA	NA	NA	NA
VEF93641.1\|998753_999425_-\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA

DBSCAN-SWA_4

1273838 : 1283732

Streptococcus_phage(33.33%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF93886.1\|1273838_1275365_+\|transposase	transposase IS663-like	Q9MBP7	Staphylococcus_prophage	7.0e-88	37.3
VEF93887.1\|1275445_1275595_-	LSU ribosomal protein L33p @ LSU ribosomal protein L33p, zinc-independent	NA	NA	NA	NA
VEF93888.1\|1275610_1275793_-	LSU ribosomal protein L32p	NA	NA	NA	NA
VEF93889.1\|1276024_1277326_+\|tRNA	histidyl-tRNA synthetase	A0A2K9L6G5	Tupanvirus	6.1e-24	25.8
VEF93890.1\|1277471_1279220_+\|tRNA	aspartyl-tRNA synthetase	A0A1V0SJ84	Klosneuvirus	5.9e-14	26.8
VEF93891.1\|1279212_1280154_+	membrane protein	NA	NA	NA	NA
VEF93892.1\|1280180_1281065_+	membrane protein	M1Q1P6	Streptococcus_phage	1.6e-44	35.0
VEF93893.1\|1281116_1281998_+	membrane protein	M1Q1P6	Streptococcus_phage	3.2e-53	38.6
VEF93894.1\|1282043_1283732_-\|tRNA	arginyl-tRNA synthetase	A0A2I2L3K1	Orpheovirus	1.8e-76	32.9

DBSCAN-SWA_5

1389000 : 1407776

Streptococcus_phage(66.67%)

transposase,integrase

attL 1389817:1389832|attR 1417151:1417166

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF93988.1\|1389000_1390713_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.9e-34	28.7
1389817:1389832	attL	NA	NA	NA	NA
VEF93989.1\|1390712_1392497_+	ABC transporter, ATP-binding protein	W8CYL7	Bacillus_phage	2.1e-43	28.9
VEF93990.1\|1392595_1393381_+	hypothetical cytosolic protein	NA	NA	NA	NA
VEF93991.1\|1393422_1394670_-	NADPH-dependent FMN reductase	A0A2P0ZL82	Lactobacillus_phage	1.3e-60	51.3
VEF93992.1\|1394688_1395291_-	NADPH-dependent FMN reductase	A0A2P0ZL77	Lactobacillus_phage	8.4e-53	52.7
VEF93993.1\|1395471_1395831_+	membrane protein	NA	NA	NA	NA
VEF93994.1\|1396389_1396623_+\|transposase	ISSag8, transposase	A0A1X9I5T2	Streptococcus_phage	3.7e-25	75.4
VEF93995.1\|1396619_1396811_+\|transposase	ISSag8, transposase	A0A1X9I5T2	Streptococcus_phage	1.1e-22	81.4
VEF93996.1\|1396905_1397832_+\|transposase	ISSag8, transposase	A0A1X9I5T2	Streptococcus_phage	5.0e-121	71.2
VEF93997.1\|1398890_1399160_-	RelE-domain-containing protein	A0A1S5S8E8	Streptococcus_phage	3.3e-17	48.8
VEF93998.1\|1399149_1399377_-	RelB protein	A0A1X9I609	Streptococcus_phage	2.0e-07	43.7
VEF93999.1\|1399515_1399605_-	Uncharacterised protein	NA	NA	NA	NA
VEF94000.1\|1399561_1399864_-	Uncharacterised protein	NA	NA	NA	NA
VEF94001.1\|1399854_1400403_-	Uncharacterised protein	A0A1X9I5V2	Streptococcus_phage	1.2e-32	44.7
VEF94002.1\|1400407_1400779_-	phage protein	NA	NA	NA	NA
VEF94003.1\|1400949_1401210_-	Uncharacterised protein	NA	NA	NA	NA
VEF94004.1\|1401321_1401639_-	DNA-binding phage protein	A0A1X9I5U9	Streptococcus_phage	1.9e-19	53.3
VEF94005.1\|1401640_1401973_-	DNA-binding phage protein	NA	NA	NA	NA
VEF94006.1\|1401987_1402179_-	phage protein	NA	NA	NA	NA
VEF94007.1\|1402160_1402400_-	Uncharacterised protein	NA	NA	NA	NA
VEF94008.1\|1403082_1403253_-	prophage ps3 protein 13	NA	NA	NA	NA
VEF94009.1\|1403264_1403450_-	DNA-binding phage protein	A0A1X9I5U7	Streptococcus_phage	7.6e-05	44.3
VEF94010.1\|1403616_1404165_+	phage-associated protein	A0A1P8VVN6	Streptococcus_phage	4.4e-16	52.9
VEF94011.1\|1404583_1404859_+	DNA-binding phage protein	O48392	Streptococcus_phage	7.8e-14	41.3
VEF94012.1\|1405034_1405997_+	phage protein	Q8HA04	Enterobacteria_phage	3.7e-34	34.7
VEF94013.1\|1406087_1406255_+\|integrase	phage integrase	NA	NA	NA	NA
VEF94014.1\|1406407_1406704_+	Integrase/recombinase, phage associated	A0A1X9I6A9	Streptococcus_phage	7.9e-12	39.3
VEF94015.1\|1406681_1407233_+\|integrase	phage integrase	A0A1X9I5Y5	Streptococcus_phage	5.7e-40	50.8
VEF94016.1\|1407329_1407776_+	deoxyuridine 5'-triphosphate nucleotidohydrolase	Q332E8	Clostridium_botulinum_C_phage	4.6e-32	49.3
1417151:1417166	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1669239 : 1679172

Streptococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF94269.1\|1669239_1671168_+	serine/threonine-protein kinase	A0A1B1IUU3	uncultured_Mediterranean_phage	5.9e-23	35.8
VEF94270.1\|1671281_1671977_+	membrane protein	NA	NA	NA	NA
VEF94271.1\|1671973_1672978_+	sensor histidine kinase	NA	NA	NA	NA
VEF94272.1\|1672970_1673612_+	response regulator protein	NA	NA	NA	NA
VEF94273.1\|1673645_1675046_+	cyclophilin type peptidyl-prolyl cis-trans isomerase protein	A0A1V0S9I2	Catovirus	1.6e-25	42.9
VEF94274.1\|1675045_1675399_+	S1 RNA binding domain-containing protein	NA	NA	NA	NA
VEF94275.1\|1675586_1676042_+\|transposase	transposase, IS200 family	A0A1P8BMC0	Lactococcus_phage	1.3e-16	36.0
VEF94276.1\|1676107_1677073_-	cysteine synthase	A0A1X9I5K7	Streptococcus_phage	7.3e-131	75.7
VEF94277.1\|1677185_1677815_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	3.0e-61	57.4
VEF94278.1\|1677870_1679172_+	late competence protein	A0A1X9I5S6	Streptococcus_phage	1.7e-122	52.8

DBSCAN-SWA_7

1762344 : 1776064

Streptococcus_phage(84.62%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEF94361.1\|1762344_1763109_+	branched-chain amino acid transport ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.0e-15	26.1
VEF94362.1\|1763108_1763819_+	high-affinity branched-chain amino acid ABC transporter, ATP-binding protein LivF	G9BWD6	Planktothrix_phage	9.7e-16	27.4
VEF94363.1\|1763878_1764541_+	5'-AMP-activated protein kinase subunit gamma-3	M1NSC5	Streptococcus_phage	8.7e-59	55.1
VEF94364.1\|1764622_1765252_+	thymidylate kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.8
VEF94365.1\|1765272_1766148_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.7e-73	49.3
VEF94366.1\|1766144_1766945_+	stage 0 sporulation protein	NA	NA	NA	NA
VEF94367.1\|1766934_1767264_+	DNA replication initiation control protein	M1PFV3	Streptococcus_phage	3.5e-29	61.3
VEF94368.1\|1767349_1768135_+	corrin/porphyrin methyltransferase	M1PLC5	Streptococcus_phage	1.3e-98	71.3
VEF94369.1\|1768290_1768686_+	hypothetical membrane associated protein	NA	NA	NA	NA
VEF94370.1\|1768804_1769437_-	CutC family protein	NA	NA	NA	NA
VEF94371.1\|1769561_1770656_+	phosphoserine aminotransferase	M1Q1P2	Streptococcus_phage	9.6e-156	71.3
VEF94372.1\|1770679_1771231_+	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	5.0e-44	50.8
VEF94373.1\|1771284_1772463_+	D-isomer specific 2-hydroxyacid dehydrogenase	M1NSB9	Streptococcus_phage	6.1e-164	74.4
VEF94374.1\|1772524_1773004_+	methylated-DNA--protein-cysteine methyltransferase	M1PFU9	Streptococcus_phage	2.6e-41	52.5
VEF94375.1\|1773016_1773370_+	ArsC family protein	M1PLC0	Streptococcus_phage	4.2e-36	64.6
VEF94376.1\|1773348_1773510_-	Uncharacterised protein	NA	NA	NA	NA
VEF94377.1\|1773448_1773865_-	glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein	NA	NA	NA	NA
VEF94378.1\|1773874_1774258_-	glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein	NA	NA	NA	NA
VEF94379.1\|1774572_1775235_-	DNA alkylation repair enzyme	NA	NA	NA	NA
VEF94380.1\|1775236_1776064_-	3'-exo-deoxyribonuclease	M1PSC0	Streptococcus_phage	1.7e-128	80.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134341

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection