CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134381	Corynebacterium kutscheri strain NCTC11138 genome assembly, chromosome: 1	4 crisprs	DEDDh,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,WYL	0	4	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134381_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134381_1

311237-312241

TypeI-E

I-E

Consensus_repeat	Method
GGAACATCCCCGCTCGCGCGGGGACAAC	CRISPRCasFinder
GGAACATCCCCGCTCGCGCGGGGACAAC	CRT
GGAACATCCCCGCTCGCGCGGGGACAAC	PILER-CR

16 spacers

cas2,cas1,cas6e,cas5

The CRISPR arrays of LR134381_1

>merge|LR134381|1|311237-312241|CRISPRCasFinder,CRT,PILER-CR
GGAACATCCCTGCTCGCGAGGGGACAACGAGATTGACGACGGGGAGTTGGTCATCTTGGTCGGAACATCCCCGCTCGCGCGGGGACAACACGGCGGCTGATCTACCATGTCAAACCACGAATCAAACATCCCCGCTCGCGCGGGGACAACTGAATAGGTTGCTGAAACAAACCAGCCACCAAGGGAACATCCCCGCTCGCGCGGGGAAAACTGGTGTTTTGACCCACTATAAGAAGAACAATAAGGAACATCCCCGCTCGCGCGGGGACAACACCTTGCGCAATCGTAAAGGGATTACCAACCCAGGAACATCCCCGCTCGCGCGGGGACAACACCTTGCGCAATCGTAAAGGGATTACCAACCCAGGAACATCCCCGCTCGCGCGGGGACAACAGAAATATTTAATTTTCGGTTCGTAGTCAGGCCGGAACATCCCCGCTCGCGCGGGGACAACGCTTGTCGTTACCAGCATGGATCGCTTGGCACGGGAACATCCCCGCTCGCGCGGGGACAACGCTTGTCGTTACCAGCATGGATCGCTTGGCACGGGAACATCCCCGCTCGCGCGGGGACAACACCTAGTGGCCGCCGCTAAAGAAAACGGCAATAGGAACATCCCCGCTCGCGCGGGGACAACTACACCAACAGCCTCAAAAGCATCAGCGATACCGGAACATCCCCGCTCGCGCGGGGACAACAGTTTTAGGGTGTGGGGTAAAAAACAGTCTTGGGGAACATCCCCGCTCGCGCGGGGACAACCAAACAACGGGTTTACGACGCTGGTGTTAATGAGGAACATCCCCGTTCGCGCGGGGACAACCGACTGGGAGACTGTGGGTATCCTGTCGGAGGGGGAACATCCCCGCTCGCGCGGGGACAACAGGCGCATCACAGATCAAGATGTCGCCGACGCCGGAACATCCCCGCTCGCGCGGGGACAACCTTGCGTTCTTCATGAGCATAATTTAACTCAAGGGGAACATCCCCGCTCGCGCGGGGACAAC

>LR134381|1|1|311237-312241|CRISPRCasFinder
GGAACATCCCTGCTCGCGAGGGGACAAC	GAGATTGACGACGGGGAGTTGGTCATCTTGGTC
GGAACATCCCCGCTCGCGCGGGGACAAC	ACGGCGGCTGATCTACCATGTCAAACCACGAAT
CAAACATCCCCGCTCGCGCGGGGACAAC	TGAATAGGTTGCTGAAACAAACCAGCCACCAAG
GGAACATCCCCGCTCGCGCGGGGAAAAC	TGGTGTTTTGACCCACTATAAGAAGAACAATAA
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTTGCGCAATCGTAAAGGGATTACCAACCCA
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTTGCGCAATCGTAAAGGGATTACCAACCCA
GGAACATCCCCGCTCGCGCGGGGACAAC	AGAAATATTTAATTTTCGGTTCGTAGTCAGGCC
GGAACATCCCCGCTCGCGCGGGGACAAC	GCTTGTCGTTACCAGCATGGATCGCTTGGCACG
GGAACATCCCCGCTCGCGCGGGGACAAC	GCTTGTCGTTACCAGCATGGATCGCTTGGCACG
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTAGTGGCCGCCGCTAAAGAAAACGGCAATA
GGAACATCCCCGCTCGCGCGGGGACAAC	TACACCAACAGCCTCAAAAGCATCAGCGATACC
GGAACATCCCCGCTCGCGCGGGGACAAC	AGTTTTAGGGTGTGGGGTAAAAAACAGTCTTGG
GGAACATCCCCGCTCGCGCGGGGACAAC	CAAACAACGGGTTTACGACGCTGGTGTTAATGA
GGAACATCCCCGTTCGCGCGGGGACAAC	CGACTGGGAGACTGTGGGTATCCTGTCGGAGGG
GGAACATCCCCGCTCGCGCGGGGACAAC	AGGCGCATCACAGATCAAGATGTCGCCGACGCC
GGAACATCCCCGCTCGCGCGGGGACAAC	CTTGCGTTCTTCATGAGCATAATTTAACTCAAGG
GGAACATCCCCGCTCGCGCGGGGACAAC

>LR134381|1|1|311237-312241|CRT
GGAACATCCCTGCTCGCGAGGGGACAAC	GAGATTGACGACGGGGAGTTGGTCATCTTGGTC
GGAACATCCCCGCTCGCGCGGGGACAAC	ACGGCGGCTGATCTACCATGTCAAACCACGAAT
CAAACATCCCCGCTCGCGCGGGGACAAC	TGAATAGGTTGCTGAAACAAACCAGCCACCAAG
GGAACATCCCCGCTCGCGCGGGGAAAAC	TGGTGTTTTGACCCACTATAAGAAGAACAATAA
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTTGCGCAATCGTAAAGGGATTACCAACCCA
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTTGCGCAATCGTAAAGGGATTACCAACCCA
GGAACATCCCCGCTCGCGCGGGGACAAC	AGAAATATTTAATTTTCGGTTCGTAGTCAGGCC
GGAACATCCCCGCTCGCGCGGGGACAAC	GCTTGTCGTTACCAGCATGGATCGCTTGGCACG
GGAACATCCCCGCTCGCGCGGGGACAAC	GCTTGTCGTTACCAGCATGGATCGCTTGGCACG
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTAGTGGCCGCCGCTAAAGAAAACGGCAATA
GGAACATCCCCGCTCGCGCGGGGACAAC	TACACCAACAGCCTCAAAAGCATCAGCGATACC
GGAACATCCCCGCTCGCGCGGGGACAAC	AGTTTTAGGGTGTGGGGTAAAAAACAGTCTTGG
GGAACATCCCCGCTCGCGCGGGGACAAC	CAAACAACGGGTTTACGACGCTGGTGTTAATGA
GGAACATCCCCGTTCGCGCGGGGACAAC	CGACTGGGAGACTGTGGGTATCCTGTCGGAGGG
GGAACATCCCCGCTCGCGCGGGGACAAC	AGGCGCATCACAGATCAAGATGTCGCCGACGCC
GGAACATCCCCGCTCGCGCGGGGACAAC	CTTGCGTTCTTCATGAGCATAATTTAACTCAAGG
GGAACATCCCCGCTCGCGCGGGGACAAC

>LR134381|1|1|311298-312241|PILER-CR
GGAACATCCCCGCTCGCGCGGGGACAAC	ACGGCGGCTGATCTACCATGTCAAACCACGAAT
CAAACATCCCCGCTCGCGCGGGGACAAC	TGAATAGGTTGCTGAAACAAACCAGCCACCAAG
GGAACATCCCCGCTCGCGCGGGGAAAAC	TGGTGTTTTGACCCACTATAAGAAGAACAATAA
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTTGCGCAATCGTAAAGGGATTACCAACCCA
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTTGCGCAATCGTAAAGGGATTACCAACCCA
GGAACATCCCCGCTCGCGCGGGGACAAC	AGAAATATTTAATTTTCGGTTCGTAGTCAGGCC
GGAACATCCCCGCTCGCGCGGGGACAAC	GCTTGTCGTTACCAGCATGGATCGCTTGGCACG
GGAACATCCCCGCTCGCGCGGGGACAAC	GCTTGTCGTTACCAGCATGGATCGCTTGGCACG
GGAACATCCCCGCTCGCGCGGGGACAAC	ACCTAGTGGCCGCCGCTAAAGAAAACGGCAATA
GGAACATCCCCGCTCGCGCGGGGACAAC	TACACCAACAGCCTCAAAAGCATCAGCGATACC
GGAACATCCCCGCTCGCGCGGGGACAAC	AGTTTTAGGGTGTGGGGTAAAAAACAGTCTTGG
GGAACATCCCCGCTCGCGCGGGGACAAC	CAAACAACGGGTTTACGACGCTGGTGTTAATGA
GGAACATCCCCGTTCGCGCGGGGACAAC	CGACTGGGAGACTGTGGGTATCCTGTCGGAGGG
GGAACATCCCCGCTCGCGCGGGGACAAC	AGGCGCATCACAGATCAAGATGTCGCCGACGCC
GGAACATCCCCGCTCGCGCGGGGACAAC	CTTGCGTTCTTCATGAGCATAATTTAACTCAAGG
GGAACATCCCCGCTCGCGCGGGGACAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134381.1\|VEH09359.1\|318565_319267_-\|CRISPR-associated-Cas5-family-protein	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|187886
LR134381.1\|VEH09350.1\|312479_313502_+\|Poly(3-hydroxybutyrate)-depolymerase	unknown	unknown	gnl\|CDD\|226040
LR134381.1\|VEH09342.1\|304313_305363_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|227119
LR134381.1\|VEH09348.1\|311114_311204_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09341.1\|303174_304125_-\|iron-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238566
LR134381.1\|VEH09343.1\|305359_306472_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182464
LR134381.1\|VEH09344.1\|306763_307561_+\|oxaloacetate-decarboxylase	unknown	unknown	gnl\|CDD\|223257
LR134381.1\|VEH09358.1\|317906_318566_-\|Cse3-family-CRISPR-associated-protein	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
LR134381.1\|VEH09357.1\|317694_317904_-\|CRISPR-associated-protein-Cas1	unknown	unknown	gnl\|CDD\|274693
LR134381.1\|VEH09353.1\|315450_315702_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09354.1\|315841_316378_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09347.1\|310479_311118_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09346.1\|308858_310340_+\|glutamyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234953
LR134381.1\|VEH09355.1\|316583_316928_-\|CRISPR-associated-protein	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
LR134381.1\|VEH09351.1\|314599_315145_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09345.1\|307661_308726_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|224091
LR134381.1\|VEH09340.1\|302386_303172_-\|iron-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
LR134381.1\|VEH09352.1\|315113_315467_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|373068
LR134381.1\|VEH09339.1\|301318_302335_+\|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl\|CDD\|179579
LR134381.1\|VEH09356.1\|316924_317698_-\|CRISPR-associated-protein-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693

Protein	Function_ID	Function_description	E-value
LR134381.1\|VEH09359.1\|318565_319267_-\|CRISPR-associated-Cas5-family-protein	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.94489e-54
LR134381.1\|VEH09350.1\|312479_313502_+\|Poly(3-hydroxybutyrate)-depolymerase	gnl\|CDD\|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	4.41586e-35
LR134381.1\|VEH09341.1\|303174_304125_-\|iron-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	1.47726e-61
LR134381.1\|VEH09355.1\|316583_316928_-\|CRISPR-associated-protein	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	6.73784e-36
LR134381.1\|VEH09343.1\|305359_306472_-\|iron-ABC-transporter-permease	gnl\|CDD\|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	6.18909e-85
LR134381.1\|VEH09344.1\|306763_307561_+\|oxaloacetate-decarboxylase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.87409e-87
LR134381.1\|VEH09358.1\|317906_318566_-\|Cse3-family-CRISPR-associated-protein	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.44302e-65
LR134381.1\|VEH09357.1\|317694_317904_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.37149e-11
LR134381.1\|VEH09346.1\|308858_310340_+\|glutamyl-tRNA-synthetase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
LR134381.1\|VEH09345.1\|307661_308726_-\|isochorismate-synthase	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.22178e-112
LR134381.1\|VEH09342.1\|304313_305363_-\|iron-ABC-transporter-permease	gnl\|CDD\|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	4.89268e-74
LR134381.1\|VEH09340.1\|302386_303172_-\|iron-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	1.19571e-124
LR134381.1\|VEH09352.1\|315113_315467_+\|Uncharacterised-protein	gnl\|CDD\|373068	pfam14436, EndoU_bacteria, Bacterial EndoU nuclease. This is a bacterial virion of EndoU nuclease. It is found at C-terminal region of polymorphic toxin proteins.	5.66218e-05
LR134381.1\|VEH09339.1\|301318_302335_+\|3-isopropylmalate-dehydrogenase	gnl\|CDD\|179579	PRK03437, PRK03437, 3-isopropylmalate dehydrogenase; Provisional.	0
LR134381.1\|VEH09356.1\|316924_317698_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.13948e-100

>LR134381.1|VEH09348.1|311114_311204_-|Uncharacterised-protein
MLQELGPRSILTPMIKETCFQNPKKGEDL
>LR134381.1|VEH09347.1|310479_311118_-|Uncharacterised-protein
MSAQRTKNRSTAALRRNMSVKEFDAGYFYAAELKRFAREIGISVGNRRKFEVEDLIRSFLETGVVPTSQPTLPRNKGEERDRLVLDEQVRNYVDDKETKEFLLDAVRSSSPGIKKKSGQWYWLNDWRRKQQERHAVFTYQDVVDHLSQLMHQEGRLPQVPSARMNNFITDLRADPVNREMTRDEVQQEWRWLKKQPGPKTYAEYKRRKRQQD
>LR134381.1|VEH09346.1|308858_310340_+|glutamyl-tRNA-synthetase
MTEVRVRFCPSPTGTPHVGMVRTALFNWAHARHTGGKLVFRIEDTDAARDSEESYQAIIDSLTWLGMDWDEGVVVGGPHEPYRQSQRMDIYAEVLEKLKAAGFVYPAYSTAEEVEQRHKAAGRDPKLGYDNFDRELSQEQIAAFEAEGRQPVWRLRMPDKDWKWTDLVRGEIEFKNATQPDYVVARSNGAPLYTLVNPVDDALMGITHVLRGEDLLPSTPRQLALYEALIAIGVAKQTPEFGHLPFVMGEGNKKLSKRDPQSNLFNHRDNGIIPEGMLNYLALLGWSLSSEKDIFSMDELIENFQVENVLGNPARFDQKKLEAINADHIRLLDLDDFTTRLREYLSEYYDFPEDYPAEKFALAAELVQTRIKTLSEAWGLLSFLVTEDEDLLFDEKSAKKNLKETAIEPLEVGIAALEAVDDFSTANIEAALSKALIEDLGLKPRVAYGALRVGISGQAVSPPLFESMELLGKESTLKRLRSAREKTPFSTTE
>LR134381.1|VEH09345.1|307661_308726_-|isochorismate-synthase
MRTQGAQQHLDNIDDAVDLLRAKKVDMVVGALAFRRDHKAALTVPVSIIREDGPLEPHAYYRHGSGAILRAQLAKLIPDIEEHHIRVQAAIDTISRSELKKVVLARAIDIDFSPPVDPRLVAARLIDLSFTKDGFIADLSPAGEDFLGHTLVGSSPEVLIKKQGSTISAYPLAGSAARSMIPREDKLRGEELRRSSKDLVEHQFVVEHLRRLLIPLCSTLTIPDYPELTCTNEMWHLATPVVGTLKDPHYTALELARLIHPTPAICGTPTDAAEELIALAEGDRRFYAGAVGWCDNTGDGEYMVAIRCAEINAEGTHARAWAGGGIVAESDAHAEVAETSAKLRTIAKALGLKI
>LR134381.1|VEH09344.1|306763_307561_+|oxaloacetate-decarboxylase
MRFGRIATPDGLSFCVVEGKQGQEVCRAIAGTPFEEPVFTGKEYKLSEVRVLAPMLPSKIVAVGRNYADHVAEVFQKSAEHLPPTLFLKPPTAVVGPEAAIKIPPFATNVEFEGELAVVIGRPCKNVKAADWKSVVLGFTIINDVSSRDLQFSDGQWARAKGIDTFAPLGPWIQTDIDSIDTSNLPIKAHLTHDGVTETKQDSNSNQMIKTVGECIEMITQSMTLLPGDVICTGSPAGTAEMVPGDYIEIEIPGIGKLGNPVEAG
>LR134381.1|VEH09343.1|305359_306472_-|iron-ABC-transporter-permease
MISSAERGHAPATTRRRGTSGRRKALGLLALMLSLTLLCICSMVLGAKATNLATINQAWPYALDILFGHTNVPQLITNGMESDLADTAGIIASLRIPRTILSILIGIALGLAGAVIQGLTRNPLADPGMLGVSSGAALFVAAGIFLFGLNTITAHLWLAFLGAGLASLLVFGISSTSVGKGDTLGLVLAGAALSASFSAITSGIVYIDPNALDTLRFWQAGSVTGRGFDIIIPALVPILIGAILALLSGPTLNVLGLGAETAQALGTNVVRANFMGLITITLLAGAATAAAGPIGFIGLMVPHIARSITGPDYRWILPYSALTGAVTLLAADIIGRLVMRPGELQAGIVIALLGAPVFIWLVRNRKMVSL
>LR134381.1|VEH09342.1|304313_305363_-|iron-ABC-transporter-permease
MSQIKNLSLGSISFLVHRRTSLFTAFILIACFVVWLISLLTGDFPMSFNQIIAVLSGGGTPLERTVIIQWRLARALVAVTIGAALGISGAITQRIARNGLASPDILGISRGATCAAVALMVFNGGASSAITTYVGIPLAAVIGGLFTAAVIWLLSVRSGLDMFRLVLVGIGVNAALQAVITYMLAATDLNTAAAAKVWMIGTINGRTFEHLWPTLIALIIALIVLIRISIHLPILELGTDASLGLGVPLKRVNTLLLIISVALAAITVSAVGPVGFVAFVAPQIAARLAQVGAPPITLSAAMGGFLLISSDLLARSLFPWEVPVGIVTSALGGPFLIWLLLRQSKIHSR
>LR134381.1|VEH09341.1|303174_304125_-|iron-ABC-transporter-substrate-binding-protein
MRKNIHQIFTHTTTRRGFLGLALAGGAAALAACSNSGSSTNSSSTSSSAAKSSTTAANEQRIVVLNTGQLDNMLTLGILPVGAAKAKGGQVINEYLRDAFGSDFDLDSITDCGVRANPELETIASLNPTLICANDRTDEAILNQLKTIAPVVTGSGGGENWKKDFVTIAEAVGKKSEAEALIASYEDECSTFGNSLTTVPTVSFLRTKDDAFQVYGVNSMAGTVAADCKLNRPSSQQFTDTAGVNISAEQLSEADADWLFYGIQDGATDPTTTSTWSTLNAVNNNQAVEVDYESWYTNASYLSATIIRDSLKEHLA
>LR134381.1|VEH09340.1|302386_303172_-|iron-ABC-transporter-ATP-binding-protein
MLESARLRATNISVGYDSTVINKDVTVDIPNGKVTTIIGANGCGKSTLLRGLSRLLPLQAGSVTLDGQELSSYKHKELARKISMLPQSPTAPPGLTVADLVARGRHPHQTWLQQWSPSHSEAVDKALELTGISDFAERSADSLSGGQRQRVWISMVLAQDTDIVFLDEPTTYLDLAHSIEVLDLVRTLNKTQGKTIVMVLHDLNLAARYSDELIIMQKGQLAAHGSPKDILNETALFDAFGLRSRIIEDPCAGGPLIVPEA
>LR134381.1|VEH09339.1|301318_302335_+|3-isopropylmalate-dehydrogenase
MKLAVIGGDGIGPEVTAEALKVLCSVRDDIEITDYDLGARRYLKNGELLTEADLASLKEHDAILLGAIGAPDQVPPGILERGLLLKMRFALDHHINLRPAKLYPSTQSPLTNPGDIDFVVVREGTEGLYCGNGGVLRKGTAQEIASEVSQNTRYGVERVVRDAFTRAQHRRKHLTLVHKTNVLVNAGSLWHRTVEEVSQEYPEVTVEYNHIDAATIYLVTDPGRYDVIVTDNLFGDILTDLAGAITGGIGLAASGNIDATGTYPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLHHLGDTAHAQRIEAAVLEEISTRSGCVSTTAIGDRVVDLLKK
>LR134381.1|VEH09350.1|312479_313502_+|Poly(3-hydroxybutyrate)-depolymerase
MNIFFPLRCFIHALNAAVLSIVLILSVIPVVSAQEVADSILEESEENYVQDNSVSVLLEGAGDVAEAEIIEAPVEDAVTVLDVPELPVVAGQTMSIETLTADAMSRRYLLSVPVNYDSGIAVPVLFAFGGWNNSPEVFRDYSRLNEIAGEEAIIVYPEGVGHAWAGAPYALTSQEQDINFVRQIIDEVAHHYTVDRERIYATGMSNGGGMAALLGCHVPELFAGIAMVSGAYYTPVNQNCSSISIPSLFIHGTDDDVVHYEGGQRHEAYYFPVAEMLASYAERNACTNTPPRTTFVGVGVERQEFENCAAETQHIKALGQAHIWNTEPNAAWEVWSFLAR
>LR134381.1|VEH09351.1|314599_315145_+|Uncharacterised-protein
MWVKDLDSLAEREKAKRKLQGVLNRLVVQPARDTVGLGVLQAGTAYARVAEPGACAFCLMLAARGEVYSDSTVFGDTGRYHDNCRCLAIEVKNKSQLPRLNRDLADLWEETRQGHGGTLEFKDWRHTITAMREQYGGDTDWPKLKYARIPTYRYGGKSVVFEGEEITPFEENAGACATWVA
>LR134381.1|VEH09352.1|315113_315467_+|Uncharacterised-protein
MPGHVLHGWREHPARDGSGRPHDESLADGHRWDSQREGVSKFPKAWTDQKIVDAVRDTLENPSFYFAKDTRRAVWREIDGVLIEVSYDILPGGKVVFNTAHPAKTIKKKAKRNANRS
>LR134381.1|VEH09353.1|315450_315702_+|Uncharacterised-protein
MLTDLEIYRRVDAMIPVEVDRDDAEHELLHCEYEDAIADLLTEAFLSGKLPQNAIDFVSSEYKHGTVAITLEYIAAQMKQSAA
>LR134381.1|VEH09354.1|315841_316378_+|Uncharacterised-protein
MDQTETTTSQHETPTPNDVAAKTTEAKNQDTQPEMFDREYVEKLRREAAGYRTKLKEIEPLAAQFKKQQEESKTELDKALERIAELEASEQRKTIEAARSGMAAKHGVPVELLPVTADSEELEAAAQALVAWAEKKTSKGAPKVDSAGGGSVADDRDAIARKRNIPARAGTTGQYRQA
>LR134381.1|VEH09355.1|316583_316928_-|CRISPR-associated-protein
MITIVLTACPAGLRGQLNRWLFEISAGVFVGHVSTRIRDRLWSIIVSELKNGRAIMAFSTSKNETGFEIKVHRHDWEIIDSDGIPLVLRPTRSNPESPLRKGWSKASQRRRKRK
>LR134381.1|VEH09356.1|316924_317698_-|CRISPR-associated-protein-Cas1
MTVIADSGASVVWCGENGVRYYAHGRPIGRNTTLLVKQAQLVSHTRSRLAVARAMYKMRFDDEAVDNLTMQQLRGKEGARVRNIYRQWADNTGVQWNKRTYNPEDFFDSDLINQALSSAHISLYGLVHSVIVALGLSPGLGFIHTGHDRSFVYDIADLYKAEVSIPIAFESVAAVEAGKVSPGDLPQYVRRQCRDAFKTNKILPRIVSDLKELLLDDSETSSDSFSIKNKVIELWDEKLERVSGGYNWDDSSGDDYP
>LR134381.1|VEH09357.1|317694_317904_-|CRISPR-associated-protein-Cas1
MKNSGFRPSTPAELTRVNERISFIYLEHCTIGRDANALTATDERGVIHIPSASLSVLLLAQEHELLTKL
>LR134381.1|VEH09358.1|317906_318566_-|Cse3-family-CRISPR-associated-protein
MTFLSAIDLNPYRRKTALFASNPRTLHAAVMNCFSPDLHAKEKRILWRLDQSTDRISLLVLSENRPCFEHIQEQAGWSNQPSSKIRDYNPLLEGLQPGQQYRFRLAANPTRIVTQSDGKKIRAAHVTVKHQKQWLRDKITAHGFSIYNGNTTDDETEMLLVTRRDRLRFNREKARVTLNRVQFDGVLTVESPELLRNAMLNGIGRGKGYGMGLLTLSAS
>LR134381.1|VEH09359.1|318565_319267_-|CRISPR-associated-Cas5-family-protein
MSVLLLKLAGPLQSWGDHSRFMHRDTRREPTKSGVIGLLAAAQGRLRTDTITDLAELRFGVRTDQIGTVISDFQTEIDWRNREAEPLTHRDYLADAIFVAAVEGSTSVITELAEAVKSPKFPLFLGRRACPPSGQLLIGIKENSLVECLENEKWHASCWYKKKQPKKVQLRLSYDAHGDDPISEMVSDVPKSFDLKNREYGVRAVTHRFTSDIDNPKGWEMKDHNPFTLLGDA

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Crispr_ID: LR134381_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134381_2

313946-314019

TypeI-E

Consensus_repeat	Method
ATCCCCGCTCGCGCGGGGACAAC	CRISPRCasFinder

1 spacers

cas2,cas1,cas6e,cas5,cas7

The CRISPR arrays of LR134381_2

>merge|LR134381|2|313946-314019|CRISPRCasFinder
ATCCCCGCTCGCGCGGGGACAACGAAGACCTAGTACATTAGATACAGGAACATCCCAGCTCGCGCGGGGACAAC

>LR134381|2|2|313946-314019|CRISPRCasFinder
ATCCCCGCTCGCGCGGGGACAAC	GAAGACCTAGTACATTAGATACAGGAAC
ATCCCAGCTCGCGCGGGGACAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134381.1\|VEH09359.1\|318565_319267_-\|CRISPR-associated-Cas5-family-protein	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|187886
LR134381.1\|VEH09350.1\|312479_313502_+\|Poly(3-hydroxybutyrate)-depolymerase	unknown	unknown	gnl\|CDD\|226040
LR134381.1\|VEH09341.1\|303174_304125_-\|iron-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238566
LR134381.1\|VEH09348.1\|311114_311204_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09343.1\|305359_306472_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182464
LR134381.1\|VEH09347.1\|310479_311118_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09358.1\|317906_318566_-\|Cse3-family-CRISPR-associated-protein	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
LR134381.1\|VEH09357.1\|317694_317904_-\|CRISPR-associated-protein-Cas1	unknown	unknown	gnl\|CDD\|274693
LR134381.1\|VEH09353.1\|315450_315702_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09354.1\|315841_316378_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09349.1\|311707_312247_+\|Domain-of-uncharacterised-function-(DUF2825)	unknown	unknown	unknown
LR134381.1\|VEH09346.1\|308858_310340_+\|glutamyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234953
LR134381.1\|VEH09355.1\|316583_316928_-\|CRISPR-associated-protein	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
LR134381.1\|VEH09351.1\|314599_315145_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09344.1\|306763_307561_+\|oxaloacetate-decarboxylase	unknown	unknown	gnl\|CDD\|223257
LR134381.1\|VEH09345.1\|307661_308726_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|224091
LR134381.1\|VEH09342.1\|304313_305363_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|227119
LR134381.1\|VEH09352.1\|315113_315467_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|373068
LR134381.1\|VEH09360.1\|319263_320406_-\|CRISPR-associated-Cse4-family-protein	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
LR134381.1\|VEH09356.1\|316924_317698_-\|CRISPR-associated-protein-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693

Protein	Function_ID	Function_description	E-value
LR134381.1\|VEH09359.1\|318565_319267_-\|CRISPR-associated-Cas5-family-protein	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.94489e-54
LR134381.1\|VEH09350.1\|312479_313502_+\|Poly(3-hydroxybutyrate)-depolymerase	gnl\|CDD\|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	4.41586e-35
LR134381.1\|VEH09355.1\|316583_316928_-\|CRISPR-associated-protein	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	6.73784e-36
LR134381.1\|VEH09341.1\|303174_304125_-\|iron-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	1.47726e-61
LR134381.1\|VEH09343.1\|305359_306472_-\|iron-ABC-transporter-permease	gnl\|CDD\|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	6.18909e-85
LR134381.1\|VEH09344.1\|306763_307561_+\|oxaloacetate-decarboxylase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.87409e-87
LR134381.1\|VEH09358.1\|317906_318566_-\|Cse3-family-CRISPR-associated-protein	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.44302e-65
LR134381.1\|VEH09357.1\|317694_317904_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.37149e-11
LR134381.1\|VEH09360.1\|319263_320406_-\|CRISPR-associated-Cse4-family-protein	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.16203e-143
LR134381.1\|VEH09346.1\|308858_310340_+\|glutamyl-tRNA-synthetase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
LR134381.1\|VEH09345.1\|307661_308726_-\|isochorismate-synthase	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.22178e-112
LR134381.1\|VEH09342.1\|304313_305363_-\|iron-ABC-transporter-permease	gnl\|CDD\|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	4.89268e-74
LR134381.1\|VEH09352.1\|315113_315467_+\|Uncharacterised-protein	gnl\|CDD\|373068	pfam14436, EndoU_bacteria, Bacterial EndoU nuclease. This is a bacterial virion of EndoU nuclease. It is found at C-terminal region of polymorphic toxin proteins.	5.66218e-05
LR134381.1\|VEH09356.1\|316924_317698_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.13948e-100

>LR134381.1|VEH09350.1|312479_313502_+|Poly(3-hydroxybutyrate)-depolymerase
MNIFFPLRCFIHALNAAVLSIVLILSVIPVVSAQEVADSILEESEENYVQDNSVSVLLEGAGDVAEAEIIEAPVEDAVTVLDVPELPVVAGQTMSIETLTADAMSRRYLLSVPVNYDSGIAVPVLFAFGGWNNSPEVFRDYSRLNEIAGEEAIIVYPEGVGHAWAGAPYALTSQEQDINFVRQIIDEVAHHYTVDRERIYATGMSNGGGMAALLGCHVPELFAGIAMVSGAYYTPVNQNCSSISIPSLFIHGTDDDVVHYEGGQRHEAYYFPVAEMLASYAERNACTNTPPRTTFVGVGVERQEFENCAAETQHIKALGQAHIWNTEPNAAWEVWSFLAR
>LR134381.1|VEH09349.1|311707_312247_+|Domain-of-uncharacterised-function-(DUF2825)
MDRLAREHPRSRGDNACRYQHGSLGTGTSPLARGQHLVAAAKENGNRNIPARAGTTTPTASKASAIPEHPRSRGDNSFRVWGKKQSWGTSPLARGQPNNGFTTLVLMRNIPVRAGTTDWETVGILSEGEHPRSRGDNRRITDQDVADAGTSPLARGQPCVLHEHNLTQGEHPRSRGDNT
>LR134381.1|VEH09348.1|311114_311204_-|Uncharacterised-protein
MLQELGPRSILTPMIKETCFQNPKKGEDL
>LR134381.1|VEH09347.1|310479_311118_-|Uncharacterised-protein
MSAQRTKNRSTAALRRNMSVKEFDAGYFYAAELKRFAREIGISVGNRRKFEVEDLIRSFLETGVVPTSQPTLPRNKGEERDRLVLDEQVRNYVDDKETKEFLLDAVRSSSPGIKKKSGQWYWLNDWRRKQQERHAVFTYQDVVDHLSQLMHQEGRLPQVPSARMNNFITDLRADPVNREMTRDEVQQEWRWLKKQPGPKTYAEYKRRKRQQD
>LR134381.1|VEH09346.1|308858_310340_+|glutamyl-tRNA-synthetase
MTEVRVRFCPSPTGTPHVGMVRTALFNWAHARHTGGKLVFRIEDTDAARDSEESYQAIIDSLTWLGMDWDEGVVVGGPHEPYRQSQRMDIYAEVLEKLKAAGFVYPAYSTAEEVEQRHKAAGRDPKLGYDNFDRELSQEQIAAFEAEGRQPVWRLRMPDKDWKWTDLVRGEIEFKNATQPDYVVARSNGAPLYTLVNPVDDALMGITHVLRGEDLLPSTPRQLALYEALIAIGVAKQTPEFGHLPFVMGEGNKKLSKRDPQSNLFNHRDNGIIPEGMLNYLALLGWSLSSEKDIFSMDELIENFQVENVLGNPARFDQKKLEAINADHIRLLDLDDFTTRLREYLSEYYDFPEDYPAEKFALAAELVQTRIKTLSEAWGLLSFLVTEDEDLLFDEKSAKKNLKETAIEPLEVGIAALEAVDDFSTANIEAALSKALIEDLGLKPRVAYGALRVGISGQAVSPPLFESMELLGKESTLKRLRSAREKTPFSTTE
>LR134381.1|VEH09345.1|307661_308726_-|isochorismate-synthase
MRTQGAQQHLDNIDDAVDLLRAKKVDMVVGALAFRRDHKAALTVPVSIIREDGPLEPHAYYRHGSGAILRAQLAKLIPDIEEHHIRVQAAIDTISRSELKKVVLARAIDIDFSPPVDPRLVAARLIDLSFTKDGFIADLSPAGEDFLGHTLVGSSPEVLIKKQGSTISAYPLAGSAARSMIPREDKLRGEELRRSSKDLVEHQFVVEHLRRLLIPLCSTLTIPDYPELTCTNEMWHLATPVVGTLKDPHYTALELARLIHPTPAICGTPTDAAEELIALAEGDRRFYAGAVGWCDNTGDGEYMVAIRCAEINAEGTHARAWAGGGIVAESDAHAEVAETSAKLRTIAKALGLKI
>LR134381.1|VEH09344.1|306763_307561_+|oxaloacetate-decarboxylase
MRFGRIATPDGLSFCVVEGKQGQEVCRAIAGTPFEEPVFTGKEYKLSEVRVLAPMLPSKIVAVGRNYADHVAEVFQKSAEHLPPTLFLKPPTAVVGPEAAIKIPPFATNVEFEGELAVVIGRPCKNVKAADWKSVVLGFTIINDVSSRDLQFSDGQWARAKGIDTFAPLGPWIQTDIDSIDTSNLPIKAHLTHDGVTETKQDSNSNQMIKTVGECIEMITQSMTLLPGDVICTGSPAGTAEMVPGDYIEIEIPGIGKLGNPVEAG
>LR134381.1|VEH09343.1|305359_306472_-|iron-ABC-transporter-permease
MISSAERGHAPATTRRRGTSGRRKALGLLALMLSLTLLCICSMVLGAKATNLATINQAWPYALDILFGHTNVPQLITNGMESDLADTAGIIASLRIPRTILSILIGIALGLAGAVIQGLTRNPLADPGMLGVSSGAALFVAAGIFLFGLNTITAHLWLAFLGAGLASLLVFGISSTSVGKGDTLGLVLAGAALSASFSAITSGIVYIDPNALDTLRFWQAGSVTGRGFDIIIPALVPILIGAILALLSGPTLNVLGLGAETAQALGTNVVRANFMGLITITLLAGAATAAAGPIGFIGLMVPHIARSITGPDYRWILPYSALTGAVTLLAADIIGRLVMRPGELQAGIVIALLGAPVFIWLVRNRKMVSL
>LR134381.1|VEH09342.1|304313_305363_-|iron-ABC-transporter-permease
MSQIKNLSLGSISFLVHRRTSLFTAFILIACFVVWLISLLTGDFPMSFNQIIAVLSGGGTPLERTVIIQWRLARALVAVTIGAALGISGAITQRIARNGLASPDILGISRGATCAAVALMVFNGGASSAITTYVGIPLAAVIGGLFTAAVIWLLSVRSGLDMFRLVLVGIGVNAALQAVITYMLAATDLNTAAAAKVWMIGTINGRTFEHLWPTLIALIIALIVLIRISIHLPILELGTDASLGLGVPLKRVNTLLLIISVALAAITVSAVGPVGFVAFVAPQIAARLAQVGAPPITLSAAMGGFLLISSDLLARSLFPWEVPVGIVTSALGGPFLIWLLLRQSKIHSR
>LR134381.1|VEH09341.1|303174_304125_-|iron-ABC-transporter-substrate-binding-protein
MRKNIHQIFTHTTTRRGFLGLALAGGAAALAACSNSGSSTNSSSTSSSAAKSSTTAANEQRIVVLNTGQLDNMLTLGILPVGAAKAKGGQVINEYLRDAFGSDFDLDSITDCGVRANPELETIASLNPTLICANDRTDEAILNQLKTIAPVVTGSGGGENWKKDFVTIAEAVGKKSEAEALIASYEDECSTFGNSLTTVPTVSFLRTKDDAFQVYGVNSMAGTVAADCKLNRPSSQQFTDTAGVNISAEQLSEADADWLFYGIQDGATDPTTTSTWSTLNAVNNNQAVEVDYESWYTNASYLSATIIRDSLKEHLA
>LR134381.1|VEH09351.1|314599_315145_+|Uncharacterised-protein
MWVKDLDSLAEREKAKRKLQGVLNRLVVQPARDTVGLGVLQAGTAYARVAEPGACAFCLMLAARGEVYSDSTVFGDTGRYHDNCRCLAIEVKNKSQLPRLNRDLADLWEETRQGHGGTLEFKDWRHTITAMREQYGGDTDWPKLKYARIPTYRYGGKSVVFEGEEITPFEENAGACATWVA
>LR134381.1|VEH09352.1|315113_315467_+|Uncharacterised-protein
MPGHVLHGWREHPARDGSGRPHDESLADGHRWDSQREGVSKFPKAWTDQKIVDAVRDTLENPSFYFAKDTRRAVWREIDGVLIEVSYDILPGGKVVFNTAHPAKTIKKKAKRNANRS
>LR134381.1|VEH09353.1|315450_315702_+|Uncharacterised-protein
MLTDLEIYRRVDAMIPVEVDRDDAEHELLHCEYEDAIADLLTEAFLSGKLPQNAIDFVSSEYKHGTVAITLEYIAAQMKQSAA
>LR134381.1|VEH09354.1|315841_316378_+|Uncharacterised-protein
MDQTETTTSQHETPTPNDVAAKTTEAKNQDTQPEMFDREYVEKLRREAAGYRTKLKEIEPLAAQFKKQQEESKTELDKALERIAELEASEQRKTIEAARSGMAAKHGVPVELLPVTADSEELEAAAQALVAWAEKKTSKGAPKVDSAGGGSVADDRDAIARKRNIPARAGTTGQYRQA
>LR134381.1|VEH09355.1|316583_316928_-|CRISPR-associated-protein
MITIVLTACPAGLRGQLNRWLFEISAGVFVGHVSTRIRDRLWSIIVSELKNGRAIMAFSTSKNETGFEIKVHRHDWEIIDSDGIPLVLRPTRSNPESPLRKGWSKASQRRRKRK
>LR134381.1|VEH09356.1|316924_317698_-|CRISPR-associated-protein-Cas1
MTVIADSGASVVWCGENGVRYYAHGRPIGRNTTLLVKQAQLVSHTRSRLAVARAMYKMRFDDEAVDNLTMQQLRGKEGARVRNIYRQWADNTGVQWNKRTYNPEDFFDSDLINQALSSAHISLYGLVHSVIVALGLSPGLGFIHTGHDRSFVYDIADLYKAEVSIPIAFESVAAVEAGKVSPGDLPQYVRRQCRDAFKTNKILPRIVSDLKELLLDDSETSSDSFSIKNKVIELWDEKLERVSGGYNWDDSSGDDYP
>LR134381.1|VEH09357.1|317694_317904_-|CRISPR-associated-protein-Cas1
MKNSGFRPSTPAELTRVNERISFIYLEHCTIGRDANALTATDERGVIHIPSASLSVLLLAQEHELLTKL
>LR134381.1|VEH09358.1|317906_318566_-|Cse3-family-CRISPR-associated-protein
MTFLSAIDLNPYRRKTALFASNPRTLHAAVMNCFSPDLHAKEKRILWRLDQSTDRISLLVLSENRPCFEHIQEQAGWSNQPSSKIRDYNPLLEGLQPGQQYRFRLAANPTRIVTQSDGKKIRAAHVTVKHQKQWLRDKITAHGFSIYNGNTTDDETEMLLVTRRDRLRFNREKARVTLNRVQFDGVLTVESPELLRNAMLNGIGRGKGYGMGLLTLSAS
>LR134381.1|VEH09359.1|318565_319267_-|CRISPR-associated-Cas5-family-protein
MSVLLLKLAGPLQSWGDHSRFMHRDTRREPTKSGVIGLLAAAQGRLRTDTITDLAELRFGVRTDQIGTVISDFQTEIDWRNREAEPLTHRDYLADAIFVAAVEGSTSVITELAEAVKSPKFPLFLGRRACPPSGQLLIGIKENSLVECLENEKWHASCWYKKKQPKKVQLRLSYDAHGDDPISEMVSDVPKSFDLKNREYGVRAVTHRFTSDIDNPKGWEMKDHNPFTLLGDA
>LR134381.1|VEH09360.1|319263_320406_-|CRISPR-associated-Cse4-family-protein
MSRMFIDIHILQTIPPSNVNRDDTGAPKTSIYGGVRRARVSSQAWKKATRESFKEYLDATELGERTFYAVDRIAKSIIESRPDLADKAVSLAEEIFKVAKIKISPEKKKNNDETASPKSVTSYLLFLSRIQISNLAQLAIQAHDTGESFNRKTINKIIQSDNSIDIALFGRMITDSPDLNVDAACQVSHAFSVHPAEIEFDYFTASDDNKENDTSGAGMIGTVEFVAPTHYRYATINTEGLISNLDSVEAAARATEAFLRSFILSMPTGKMNTFANRTRPELVLVQIRQDQPVNLAESFEKAITTTTGRMAKATIELASSAKNADETYGSAAKESFYLATNNADTPETRAELDAIGTHVTFDDLISLVGKAVRSRAENNA

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Click the colored protein region to show detailed information

Crispr_ID: LR134381_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134381_3

316329-316539

TypeI-E

I-E

Consensus_repeat	Method
GGAACATCCCCGCTCGCGCGGGGACAAC	PILER-CR
GGAACATCCCCGCTCGCGCGGGGACAAC	CRISPRCasFinder
GGAACATCCCCGCTCGCGCGGGGACAAC	CRT

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of LR134381_3

>merge|LR134381|3|316329-316539|PILER-CR,CRISPRCasFinder,CRT
GGAACATCCCCGCTCGCGCGGGGACAACCGGTCAGTATCGACAGGCTTGAAGGGCGCGCTCGGAACATCCCCGCTCGCGCGGGGACAACTTTTTTCTCTTGTGATGGTTTTTCGATGATGCTGGAACATCCCCGCTCGCGCGGGGACAACAACACCCCCTAGGAAAACACCTAGGGGGTTCGGGGAACATCCCCGCTCGCGCGGGGACAAC

>LR134381|3|2|316329-316539|PILER-CR
GGAACATCCCCGCTCGCGCGGGGACAAC	CGGTCAGTATCGACAGGCTTGAAGGGCGCGCTC
GGAACATCCCCGCTCGCGCGGGGACAAC	TTTTTTCTCTTGTGATGGTTTTTCGATGATGCT
GGAACATCCCCGCTCGCGCGGGGACAAC	AACACCCCCTAGGAAAACACCTAGGGGGTTCGG
GGAACATCCCCGCTCGCGCGGGGACAAC

>LR134381|3|3|316329-316539|CRISPRCasFinder
GGAACATCCCCGCTCGCGCGGGGACAAC	CGGTCAGTATCGACAGGCTTGAAGGGCGCGCTC
GGAACATCCCCGCTCGCGCGGGGACAAC	TTTTTTCTCTTGTGATGGTTTTTCGATGATGCT
GGAACATCCCCGCTCGCGCGGGGACAAC	AACACCCCCTAGGAAAACACCTAGGGGGTTCGG
GGAACATCCCCGCTCGCGCGGGGACAAC

>LR134381|3|2|316329-316539|CRT
GGAACATCCCCGCTCGCGCGGGGACAAC	CGGTCAGTATCGACAGGCTTGAAGGGCGCGCTC
GGAACATCCCCGCTCGCGCGGGGACAAC	TTTTTTCTCTTGTGATGGTTTTTCGATGATGCT
GGAACATCCCCGCTCGCGCGGGGACAAC	AACACCCCCTAGGAAAACACCTAGGGGGTTCGG
GGAACATCCCCGCTCGCGCGGGGACAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134381.1\|VEH09359.1\|318565_319267_-\|CRISPR-associated-Cas5-family-protein	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|187886
LR134381.1\|VEH09350.1\|312479_313502_+\|Poly(3-hydroxybutyrate)-depolymerase	unknown	unknown	gnl\|CDD\|226040
LR134381.1\|VEH09355.1\|316583_316928_-\|CRISPR-associated-protein	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
LR134381.1\|VEH09348.1\|311114_311204_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09347.1\|310479_311118_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09358.1\|317906_318566_-\|Cse3-family-CRISPR-associated-protein	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
LR134381.1\|VEH09357.1\|317694_317904_-\|CRISPR-associated-protein-Cas1	unknown	unknown	gnl\|CDD\|274693
LR134381.1\|VEH09353.1\|315450_315702_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09349.1\|311707_312247_+\|Domain-of-uncharacterised-function-(DUF2825)	unknown	unknown	unknown
LR134381.1\|VEH09346.1\|308858_310340_+\|glutamyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234953
LR134381.1\|VEH09364.1\|326191_326737_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
LR134381.1\|VEH09351.1\|314599_315145_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH09344.1\|306763_307561_+\|oxaloacetate-decarboxylase	unknown	unknown	gnl\|CDD\|223257
LR134381.1\|VEH09363.1\|322801_325663_-\|putative-CRISPR-associated-helicase-Cas3-family-protein	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
LR134381.1\|VEH09345.1\|307661_308726_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|224091
LR134381.1\|VEH09361.1\|320445_321078_-\|CRISPR-associated-Cse2-family-protein	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191
LR134381.1\|VEH09352.1\|315113_315467_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|373068
LR134381.1\|VEH09360.1\|319263_320406_-\|CRISPR-associated-Cse4-family-protein	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
LR134381.1\|VEH09362.1\|321058_322708_-\|CRISPR-associated-Cse1-family-protein	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|378189
LR134381.1\|VEH09356.1\|316924_317698_-\|CRISPR-associated-protein-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693

Protein	Function_ID	Function_description	E-value
LR134381.1\|VEH09350.1\|312479_313502_+\|Poly(3-hydroxybutyrate)-depolymerase	gnl\|CDD\|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	4.41586e-35
LR134381.1\|VEH09359.1\|318565_319267_-\|CRISPR-associated-Cas5-family-protein	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.94489e-54
LR134381.1\|VEH09355.1\|316583_316928_-\|CRISPR-associated-protein	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	6.73784e-36
LR134381.1\|VEH09344.1\|306763_307561_+\|oxaloacetate-decarboxylase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.87409e-87
LR134381.1\|VEH09357.1\|317694_317904_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.37149e-11
LR134381.1\|VEH09356.1\|316924_317698_-\|CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.13948e-100
LR134381.1\|VEH09360.1\|319263_320406_-\|CRISPR-associated-Cse4-family-protein	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.16203e-143
LR134381.1\|VEH09346.1\|308858_310340_+\|glutamyl-tRNA-synthetase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
LR134381.1\|VEH09364.1\|326191_326737_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	1.94311e-32
LR134381.1\|VEH09363.1\|322801_325663_-\|putative-CRISPR-associated-helicase-Cas3-family-protein	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.18742e-75
LR134381.1\|VEH09345.1\|307661_308726_-\|isochorismate-synthase	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.22178e-112
LR134381.1\|VEH09361.1\|320445_321078_-\|CRISPR-associated-Cse2-family-protein	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	3.65636e-29
LR134381.1\|VEH09352.1\|315113_315467_+\|Uncharacterised-protein	gnl\|CDD\|373068	pfam14436, EndoU_bacteria, Bacterial EndoU nuclease. This is a bacterial virion of EndoU nuclease. It is found at C-terminal region of polymorphic toxin proteins.	5.66218e-05
LR134381.1\|VEH09362.1\|321058_322708_-\|CRISPR-associated-Cse1-family-protein	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	4.81542e-108
LR134381.1\|VEH09358.1\|317906_318566_-\|Cse3-family-CRISPR-associated-protein	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.44302e-65

>LR134381.1|VEH09353.1|315450_315702_+|Uncharacterised-protein
MLTDLEIYRRVDAMIPVEVDRDDAEHELLHCEYEDAIADLLTEAFLSGKLPQNAIDFVSSEYKHGTVAITLEYIAAQMKQSAA
>LR134381.1|VEH09352.1|315113_315467_+|Uncharacterised-protein
MPGHVLHGWREHPARDGSGRPHDESLADGHRWDSQREGVSKFPKAWTDQKIVDAVRDTLENPSFYFAKDTRRAVWREIDGVLIEVSYDILPGGKVVFNTAHPAKTIKKKAKRNANRS
>LR134381.1|VEH09351.1|314599_315145_+|Uncharacterised-protein
MWVKDLDSLAEREKAKRKLQGVLNRLVVQPARDTVGLGVLQAGTAYARVAEPGACAFCLMLAARGEVYSDSTVFGDTGRYHDNCRCLAIEVKNKSQLPRLNRDLADLWEETRQGHGGTLEFKDWRHTITAMREQYGGDTDWPKLKYARIPTYRYGGKSVVFEGEEITPFEENAGACATWVA
>LR134381.1|VEH09350.1|312479_313502_+|Poly(3-hydroxybutyrate)-depolymerase
MNIFFPLRCFIHALNAAVLSIVLILSVIPVVSAQEVADSILEESEENYVQDNSVSVLLEGAGDVAEAEIIEAPVEDAVTVLDVPELPVVAGQTMSIETLTADAMSRRYLLSVPVNYDSGIAVPVLFAFGGWNNSPEVFRDYSRLNEIAGEEAIIVYPEGVGHAWAGAPYALTSQEQDINFVRQIIDEVAHHYTVDRERIYATGMSNGGGMAALLGCHVPELFAGIAMVSGAYYTPVNQNCSSISIPSLFIHGTDDDVVHYEGGQRHEAYYFPVAEMLASYAERNACTNTPPRTTFVGVGVERQEFENCAAETQHIKALGQAHIWNTEPNAAWEVWSFLAR
>LR134381.1|VEH09349.1|311707_312247_+|Domain-of-uncharacterised-function-(DUF2825)
MDRLAREHPRSRGDNACRYQHGSLGTGTSPLARGQHLVAAAKENGNRNIPARAGTTTPTASKASAIPEHPRSRGDNSFRVWGKKQSWGTSPLARGQPNNGFTTLVLMRNIPVRAGTTDWETVGILSEGEHPRSRGDNRRITDQDVADAGTSPLARGQPCVLHEHNLTQGEHPRSRGDNT
>LR134381.1|VEH09348.1|311114_311204_-|Uncharacterised-protein
MLQELGPRSILTPMIKETCFQNPKKGEDL
>LR134381.1|VEH09347.1|310479_311118_-|Uncharacterised-protein
MSAQRTKNRSTAALRRNMSVKEFDAGYFYAAELKRFAREIGISVGNRRKFEVEDLIRSFLETGVVPTSQPTLPRNKGEERDRLVLDEQVRNYVDDKETKEFLLDAVRSSSPGIKKKSGQWYWLNDWRRKQQERHAVFTYQDVVDHLSQLMHQEGRLPQVPSARMNNFITDLRADPVNREMTRDEVQQEWRWLKKQPGPKTYAEYKRRKRQQD
>LR134381.1|VEH09346.1|308858_310340_+|glutamyl-tRNA-synthetase
MTEVRVRFCPSPTGTPHVGMVRTALFNWAHARHTGGKLVFRIEDTDAARDSEESYQAIIDSLTWLGMDWDEGVVVGGPHEPYRQSQRMDIYAEVLEKLKAAGFVYPAYSTAEEVEQRHKAAGRDPKLGYDNFDRELSQEQIAAFEAEGRQPVWRLRMPDKDWKWTDLVRGEIEFKNATQPDYVVARSNGAPLYTLVNPVDDALMGITHVLRGEDLLPSTPRQLALYEALIAIGVAKQTPEFGHLPFVMGEGNKKLSKRDPQSNLFNHRDNGIIPEGMLNYLALLGWSLSSEKDIFSMDELIENFQVENVLGNPARFDQKKLEAINADHIRLLDLDDFTTRLREYLSEYYDFPEDYPAEKFALAAELVQTRIKTLSEAWGLLSFLVTEDEDLLFDEKSAKKNLKETAIEPLEVGIAALEAVDDFSTANIEAALSKALIEDLGLKPRVAYGALRVGISGQAVSPPLFESMELLGKESTLKRLRSAREKTPFSTTE
>LR134381.1|VEH09345.1|307661_308726_-|isochorismate-synthase
MRTQGAQQHLDNIDDAVDLLRAKKVDMVVGALAFRRDHKAALTVPVSIIREDGPLEPHAYYRHGSGAILRAQLAKLIPDIEEHHIRVQAAIDTISRSELKKVVLARAIDIDFSPPVDPRLVAARLIDLSFTKDGFIADLSPAGEDFLGHTLVGSSPEVLIKKQGSTISAYPLAGSAARSMIPREDKLRGEELRRSSKDLVEHQFVVEHLRRLLIPLCSTLTIPDYPELTCTNEMWHLATPVVGTLKDPHYTALELARLIHPTPAICGTPTDAAEELIALAEGDRRFYAGAVGWCDNTGDGEYMVAIRCAEINAEGTHARAWAGGGIVAESDAHAEVAETSAKLRTIAKALGLKI
>LR134381.1|VEH09344.1|306763_307561_+|oxaloacetate-decarboxylase
MRFGRIATPDGLSFCVVEGKQGQEVCRAIAGTPFEEPVFTGKEYKLSEVRVLAPMLPSKIVAVGRNYADHVAEVFQKSAEHLPPTLFLKPPTAVVGPEAAIKIPPFATNVEFEGELAVVIGRPCKNVKAADWKSVVLGFTIINDVSSRDLQFSDGQWARAKGIDTFAPLGPWIQTDIDSIDTSNLPIKAHLTHDGVTETKQDSNSNQMIKTVGECIEMITQSMTLLPGDVICTGSPAGTAEMVPGDYIEIEIPGIGKLGNPVEAG
>LR134381.1|VEH09355.1|316583_316928_-|CRISPR-associated-protein
MITIVLTACPAGLRGQLNRWLFEISAGVFVGHVSTRIRDRLWSIIVSELKNGRAIMAFSTSKNETGFEIKVHRHDWEIIDSDGIPLVLRPTRSNPESPLRKGWSKASQRRRKRK
>LR134381.1|VEH09356.1|316924_317698_-|CRISPR-associated-protein-Cas1
MTVIADSGASVVWCGENGVRYYAHGRPIGRNTTLLVKQAQLVSHTRSRLAVARAMYKMRFDDEAVDNLTMQQLRGKEGARVRNIYRQWADNTGVQWNKRTYNPEDFFDSDLINQALSSAHISLYGLVHSVIVALGLSPGLGFIHTGHDRSFVYDIADLYKAEVSIPIAFESVAAVEAGKVSPGDLPQYVRRQCRDAFKTNKILPRIVSDLKELLLDDSETSSDSFSIKNKVIELWDEKLERVSGGYNWDDSSGDDYP
>LR134381.1|VEH09357.1|317694_317904_-|CRISPR-associated-protein-Cas1
MKNSGFRPSTPAELTRVNERISFIYLEHCTIGRDANALTATDERGVIHIPSASLSVLLLAQEHELLTKL
>LR134381.1|VEH09358.1|317906_318566_-|Cse3-family-CRISPR-associated-protein
MTFLSAIDLNPYRRKTALFASNPRTLHAAVMNCFSPDLHAKEKRILWRLDQSTDRISLLVLSENRPCFEHIQEQAGWSNQPSSKIRDYNPLLEGLQPGQQYRFRLAANPTRIVTQSDGKKIRAAHVTVKHQKQWLRDKITAHGFSIYNGNTTDDETEMLLVTRRDRLRFNREKARVTLNRVQFDGVLTVESPELLRNAMLNGIGRGKGYGMGLLTLSAS
>LR134381.1|VEH09359.1|318565_319267_-|CRISPR-associated-Cas5-family-protein
MSVLLLKLAGPLQSWGDHSRFMHRDTRREPTKSGVIGLLAAAQGRLRTDTITDLAELRFGVRTDQIGTVISDFQTEIDWRNREAEPLTHRDYLADAIFVAAVEGSTSVITELAEAVKSPKFPLFLGRRACPPSGQLLIGIKENSLVECLENEKWHASCWYKKKQPKKVQLRLSYDAHGDDPISEMVSDVPKSFDLKNREYGVRAVTHRFTSDIDNPKGWEMKDHNPFTLLGDA
>LR134381.1|VEH09360.1|319263_320406_-|CRISPR-associated-Cse4-family-protein
MSRMFIDIHILQTIPPSNVNRDDTGAPKTSIYGGVRRARVSSQAWKKATRESFKEYLDATELGERTFYAVDRIAKSIIESRPDLADKAVSLAEEIFKVAKIKISPEKKKNNDETASPKSVTSYLLFLSRIQISNLAQLAIQAHDTGESFNRKTINKIIQSDNSIDIALFGRMITDSPDLNVDAACQVSHAFSVHPAEIEFDYFTASDDNKENDTSGAGMIGTVEFVAPTHYRYATINTEGLISNLDSVEAAARATEAFLRSFILSMPTGKMNTFANRTRPELVLVQIRQDQPVNLAESFEKAITTTTGRMAKATIELASSAKNADETYGSAAKESFYLATNNADTPETRAELDAIGTHVTFDDLISLVGKAVRSRAENNA
>LR134381.1|VEH09361.1|320445_321078_-|CRISPR-associated-Cse2-family-protein
MTSSISNKIASHVYSKIGPLQTNYLADYSSAKAELAELRRSANNPKASFKIWSLVFDNLDEELIGKGDRFNRAERALLTTFQLYAIHQQSSNKPMHVTAKTTGAEQSFPQGLGTAVRRIANPNDSDDWEQAILRRFSSVVNASTFEGTKHHLRGLIQIFRAKDIPLNYGLLAKDLYRLQFPEAVQSVHLRWARELYQRSPETSKTAEVSA
>LR134381.1|VEH09362.1|321058_322708_-|CRISPR-associated-Cse1-family-protein
MESHFNLLDEKWIKVIDINGIEAEISIHELLSNSSHYQAFANELPTINFAILRLLLAILEAALLEEYEDDELVEEWKNIWETGSLPIDIIDDYLTTYRHRFYLIDETYPFLQVPTLATAKNEWKKLDLIVIDSPGEGSLFTRRTANVLDLAEAARWLVHANSFDFSGIKSGAVGDDRVKGGKGYPQGIGWCGWLGGTTIIGRNLFETLMLNFVAEGDFSSLDKPIWEEEPLTAAARPYAQPHGQKGLFTWPQRRIRLKIEENKATGVLVCNGDPIDYTNQLAHENMTAWRYSEPQSKKAKKPVYMPRALQSEKMLWQGLSTLLPSDNAELVDKTGILKFKPAKNVEWVGRLIERGVLPYDYRIQLDVVTIEYGTQNASVEKVLHDSLRMSAALASIDQQELQSWVQDAVSYADKTALAVTNLAADLIIAEGYSGDKIAKKRKQTYAKMLAAIDPQFRNWLSQLSIDSDGVTLLQEWIMYLRRLGNQTAQQLLQTTSSKAWSGRKHNDHIVNVGTAASRFSFSLAKILPTTNPLQSSNNQKGDSHDIINK
>LR134381.1|VEH09363.1|322801_325663_-|putative-CRISPR-associated-helicase-Cas3-family-protein
MPDTLRINLQEPPSNLDALIWAKSQNNGEQSLPLWAHLDDAACVADLLWDNFLSHHTRNILADDCGSIERARKLAIFLAGGHDIGKASPHFTMQVGELKRRLEDAGAIFHHLDKSSLRPHSLVSAQSLHYWLSQQGKTNVALPLALIVGGHHGVYPASIISSEAKGLGKTEASLWHEIRQRLWNRAAATAGIKPEDFDFLAQGSFRAESQLILTGFIIVSDWIASNTDLFPLEVETNTDNRLRRARHAIQKLQLPKPWRPNPPDSINELFRTRFDFPDTATPRPVQESAAEIASSLESPGLMIIEAPTGEGKTEAALAAAEIFADRFQLGGLAFALPTCATSDAMFPRLLSWLDTTISPDQQASAILSHGKAEFNEDYKNIFPRRYNNFSPLYDESSGSTSSSVTAHWWLRGRKTSVLADFTIGTIDQILFAALASKHVMLRYLGLSGKVIIFDEIHSSDHYMSVYLNRILEWLGAMNCPVIALSATLAPRKRAQLIQSYRRGVMKRAGERYNKKLEQQDEKTSLAACGYPLITTVTTKGITFTAPEQSSRSSTTKVEFIGDDTDDVCNIINKVFAQGNGCIAVVRNTINRAQKTFQALKETLDGVEVILLHSKFIGPDRRATEKMLTTRLGKNASQRPHKLVVVATQVIEQSLDVDFDLMLSDIAPIDLIIQRIGRLHRHESNQTFRQPALANPLLFITGTDLKAATPNQLPQVTPALDKDSAHVYGESSLLRCIATLFLYARTDSLRICSPDDIAALVSTADEPHFSAPRGWEEKWNKAENAEKEKIIGKKNRARGFLVPSLTASSDLLSWANQRGNASEEPQQGYAQVRDSEENIEVILVQHINGTIRTLPWLKNYPSEQVDFATGIDSEVARATAQCSVQLPTFLANNSHADKIISELEKNGIESWQNSHWLKGQLPLILDENLCATVSNFTFIYDPETGLHYKQQKKD
>LR134381.1|VEH09364.1|326191_326737_+|MerR-family-transcriptional-regulator
MSNCDQTLRTVGEVAQLLGLSVRTLHYWEQRGLVVPSYRSIADYRLYSTADIERLQLVMIYKATGMSISAIIDVLSQDSMRITHLRKQRTLLIEKQAEVQQMLNAIDVLLTDAQRSVTRDYEKPTGHREYEEQNLSEENFMSMSEEHSQGEQSQLSVEEIAQILGEANFAAYQEEAEKKLG

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Crispr_ID: LR134381_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134381_4

1288273-1288849

Orphan

Consensus_repeat	Method
GTTGTCCCCGCTCGCGCGGGGATGTTCC	PILER-CR
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CRISPRCasFinder
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CRT

9 spacers

The CRISPR arrays of LR134381_4

>merge|LR134381|4|1288273-1288849|PILER-CR,CRISPRCasFinder,CRT
GTTGTCCCCGCTCGCGCGGGGATGTTCCGGTGAGATGCTTAGCGCCCTAGAGACAGTGATTGTTGTCCCCGCTCGCGCGGGGATGTTCCCGGAGTCAACATTGGCGCGAATCGGCTTTTTGCGTTGTCCCCGCTCGCGCGGGGATGTTCCTTCGCTTACTCCCACCATGGCACTGATCCTGCTGTTGTCCCCGCTCGCGCGGGGATGTTCCTTCTAGATTCAATAGTGTCCTTCCTGATGTGTGGTTGTCCCCGCTCGCGCGGGGATGTTCCGCCCGTCTTCTGTGTGTCGCTCGACCCGGTGAGGTTGTCCCCGCTCGCGCGGGGATGTTCCGGATTAGCCAATGACTATTGCAAGCCGTGAGCTGTTGTCCCCGCTCGCGCGGGGATGTTCCGTATGTACCCGCTGAAACATCAATTTCTTCCCAGTTGTCCCCGCTCGCGCGGGGATGTTCCTCCGCCATGACGTTTGACGCAACTACAGGTGTCGTTGTCCCCGCTCGCGCGGGGATGTTCCCGTGAAAAGCTTTTGTGTTTGGTGGGTGCTTTTGTTGTCCCCGCTCGCGCGGGGATGTTCC

>LR134381|4|3|1288273-1288849|PILER-CR
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GGTGAGATGCTTAGCGCCCTAGAGACAGTGATT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CGGAGTCAACATTGGCGCGAATCGGCTTTTTGC
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TTCGCTTACTCCCACCATGGCACTGATCCTGCT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TTCTAGATTCAATAGTGTCCTTCCTGATGTGTG
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GCCCGTCTTCTGTGTGTCGCTCGACCCGGTGAG
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GGATTAGCCAATGACTATTGCAAGCCGTGAGCT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GTATGTACCCGCTGAAACATCAATTTCTTCCCA
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TCCGCCATGACGTTTGACGCAACTACAGGTGTC
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CGTGAAAAGCTTTTGTGTTTGGTGGGTGCTTTT
GTTGTCCCCGCTCGCGCGGGGATGTTCC

>LR134381|4|4|1288273-1288849|CRISPRCasFinder
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GGTGAGATGCTTAGCGCCCTAGAGACAGTGATT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CGGAGTCAACATTGGCGCGAATCGGCTTTTTGC
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TTCGCTTACTCCCACCATGGCACTGATCCTGCT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TTCTAGATTCAATAGTGTCCTTCCTGATGTGTG
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GCCCGTCTTCTGTGTGTCGCTCGACCCGGTGAG
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GGATTAGCCAATGACTATTGCAAGCCGTGAGCT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GTATGTACCCGCTGAAACATCAATTTCTTCCCA
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TCCGCCATGACGTTTGACGCAACTACAGGTGTC
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CGTGAAAAGCTTTTGTGTTTGGTGGGTGCTTTT
GTTGTCCCCGCTCGCGCGGGGATGTTCC

>LR134381|4|3|1288273-1288849|CRT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GGTGAGATGCTTAGCGCCCTAGAGACAGTGATT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CGGAGTCAACATTGGCGCGAATCGGCTTTTTGC
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TTCGCTTACTCCCACCATGGCACTGATCCTGCT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TTCTAGATTCAATAGTGTCCTTCCTGATGTGTG
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GCCCGTCTTCTGTGTGTCGCTCGACCCGGTGAG
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GGATTAGCCAATGACTATTGCAAGCCGTGAGCT
GTTGTCCCCGCTCGCGCGGGGATGTTCC	GTATGTACCCGCTGAAACATCAATTTCTTCCCA
GTTGTCCCCGCTCGCGCGGGGATGTTCC	TCCGCCATGACGTTTGACGCAACTACAGGTGTC
GTTGTCCCCGCTCGCGCGGGGATGTTCC	CGTGAAAAGCTTTTGTGTTTGGTGGGTGCTTTT
GTTGTCCCCGCTCGCGCGGGGATGTTCC

Protein	Signature genes	Signature genes Name	Protein_function
LR134381.1\|VEH10233.1\|1289018_1289318_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH10222.1\|1275718_1277410_+\|UvrABC-system-protein-B	unknown	unknown	gnl\|CDD\|223989
LR134381.1\|VEH10226.1\|1278550_1278790_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|213216
LR134381.1\|VEH10242.1\|1299072_1302198_+\|type-I-site-specific-deoxyribonuclease,-HsdR-family-protein	unknown	unknown	gnl\|CDD\|223683
LR134381.1\|VEH10224.1\|1278203_1278296_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134381.1\|VEH10234.1\|1289317_1290073_-\|iron-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226963
LR134381.1\|VEH10236.1\|1291129_1292125_-\|FecCD-family-membrane-transport-protein	unknown	unknown	gnl\|CDD\|226965
LR134381.1\|VEH10223.1\|1277419_1278055_+\|hypothetical-membrane-protein	unknown	unknown	gnl\|CDD\|378679
LR134381.1\|VEH10238.1\|1293551_1294634_+\|Threonine-aldolase	unknown	unknown	gnl\|CDD\|224919
LR134381.1\|VEH10235.1\|1290069_1291137_-\|ABC-type-cobalamin/Fe3+-siderophore-transport-system,-permease	unknown	unknown	gnl\|CDD\|226964
LR134381.1\|VEH10229.1\|1279788_1280253_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
LR134381.1\|VEH10230.1\|1280249_1281119_-\|lipid-A-export-ATP-binding/permease-msbA	unknown	unknown	gnl\|CDD\|213220
LR134381.1\|VEH10225.1\|1278341_1278548_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|213193
LR134381.1\|VEH10237.1\|1292223_1293234_-\|periplasmic-binding-protein	unknown	unknown	gnl\|CDD\|226966
LR134381.1\|VEH10239.1\|1294630_1295389_-\|3-demethylubiquinone-9-3-methyltransferase	unknown	unknown	gnl\|CDD\|319899
LR134381.1\|VEH10231.1\|1281145_1281466_-\|lipid-A-export-ATP-binding/permease-msbA	unknown	unknown	unknown
LR134381.1\|VEH10227.1\|1278808_1279474_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|213218
LR134381.1\|VEH10228.1\|1279479_1279731_-\|ATP-binding-protein	unknown	unknown	unknown
LR134381.1\|VEH10240.1\|1296350_1297919_+\|type-I-restriction-modification-system,-M-subunit	unknown	unknown	gnl\|CDD\|211578
LR134381.1\|VEH10241.1\|1297915_1299076_+\|restriction-modification-system-DNA-specificity-domain-containing-protein	unknown	unknown	gnl\|CDD\|341157

Protein	Function_ID	Function_description	E-value
LR134381.1\|VEH10236.1\|1291129_1292125_-\|FecCD-family-membrane-transport-protein	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	2.3179e-125
LR134381.1\|VEH10222.1\|1275718_1277410_+\|UvrABC-system-protein-B	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	5.6094e-110
LR134381.1\|VEH10226.1\|1278550_1278790_-\|ATP-binding-protein	gnl\|CDD\|213216	cd03249, ABC_MTABC3_MDL1_MDL2, ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins. MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.	2.38289e-25
LR134381.1\|VEH10242.1\|1299072_1302198_+\|type-I-site-specific-deoxyribonuclease,-HsdR-family-protein	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
LR134381.1\|VEH10240.1\|1296350_1297919_+\|type-I-restriction-modification-system,-M-subunit	gnl\|CDD\|211578	TIGR00497, hsdM, type I restriction system adenine methylase (hsdM). Function: methylation of specific adenine residues; required for both restriction and modification activities. The ECOR124/3 I enzyme recognizes 5'GAA(N7)RTCG. for E.coli see (J. Mol. Biol. 257: 960-969 (1996)). [DNA metabolism, Restriction/modification].	0
LR134381.1\|VEH10234.1\|1289317_1290073_-\|iron-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	1.37128e-144
LR134381.1\|VEH10237.1\|1292223_1293234_-\|periplasmic-binding-protein	gnl\|CDD\|226966	COG4607, CeuA, ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism].	3.78375e-82
LR134381.1\|VEH10223.1\|1277419_1278055_+\|hypothetical-membrane-protein	gnl\|CDD\|378679	pfam11580, DUF3239, Protein of unknown function (DUF3239). This bacterial family of proteins may be membrane proteins however this cannot be confirmed. Currently there is no known function.	2.22903e-52
LR134381.1\|VEH10238.1\|1293551_1294634_+\|Threonine-aldolase	gnl\|CDD\|224919	COG2008, GLY1, Threonine aldolase [Amino acid transport and metabolism].	1.56286e-79
LR134381.1\|VEH10235.1\|1290069_1291137_-\|ABC-type-cobalamin/Fe3+-siderophore-transport-system,-permease	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	5.58209e-105
LR134381.1\|VEH10229.1\|1279788_1280253_-\|ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.96672e-07
LR134381.1\|VEH10230.1\|1280249_1281119_-\|lipid-A-export-ATP-binding/permease-msbA	gnl\|CDD\|213220	cd03253, ABCC_ATM1_transporter, ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C. ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.86733e-90
LR134381.1\|VEH10225.1\|1278341_1278548_+\|Uncharacterised-protein	gnl\|CDD\|213193	cd03226, ABC_cobalt_CbiO_domain2, Second domain of the ATP-binding cassette component of cobalt transport system. Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	2.814e-07
LR134381.1\|VEH10241.1\|1297915_1299076_+\|restriction-modification-system-DNA-specificity-domain-containing-protein	gnl\|CDD\|341157	cd17268, RMtype1_S_Ara36733I_TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to S.Ara36733I TRD1-CR1 AND S.Ara36733I TRD2-CR2. Actinomyces radicidentis S subunit (S.Ara36733I) recognizes 5'... CGAGNNNNNCTG ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	2.06164e-101
LR134381.1\|VEH10239.1\|1294630_1295389_-\|3-demethylubiquinone-9-3-methyltransferase	gnl\|CDD\|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	2.34047e-26
LR134381.1\|VEH10227.1\|1278808_1279474_-\|ATP-binding-protein	gnl\|CDD\|213218	cd03251, ABCC_MsbA, ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C. MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.47449e-62

>LR134381.1|VEH10231.1|1281145_1281466_-|lipid-A-export-ATP-binding/permease-msbA
MRQFREKADQFKTSQKQLDAAVVELVRGIPVIKVFTPEGYDESIFLHRSKHFGKFYRDWVSATVHATALMKVFTSTTFGLLVVAAGALGLVFLLKCQYSMYLQHFY
>LR134381.1|VEH10230.1|1280249_1281119_-|lipid-A-export-ATP-binding/permease-msbA
MLSRANIMFAEAKAAAADLIYFFNLAESPVAGGKEDPADTSIELDNLGFSYVEGIPVLTDIDAIFQAGSVTAVVGPSGFGKSTLASLIPRLLDPTVGTVRIGGVASTDLTYDQLYDRVGFVFQNSYLMRLSVRDNIRLASPEATDEDVIRAARAAQIHERITKLPRGYDSIRGEDAQFSGGEQQRLAIARSILLDAPILVLDEATAFADPDSEAAIQQAISQLVVGRTLVVIAHRLHTITDADQILMLDDGKLTEVGTHKELLAAGNKYAKMWQRYQNTQTSSYEETIE
>LR134381.1|VEH10229.1|1279788_1280253_-|ATP-binding-protein
MILTLYALGTDANRRRLVFVLGLIMLSSLALAVGLILVAVFLDALFIRGPGAAATWLPWIFLSVIGYAVADWPTEIIAQDLGHDYVLRIHKLIAERTVMLPLVYFDEDRSGQIGVTATSGVLFAANALAMMLRPMLHGAASAGLASVFLIVIDW
>LR134381.1|VEH10228.1|1279479_1279731_-|ATP-binding-protein
MQQYRIVERNKGVHNEHSAAQVLEFAQVQPMLRVAGSDSLGKRSVRAGIREQFFAQQQTQKTGEMVMGLLATIIMIVALLLMH
>LR134381.1|VEH10227.1|1278808_1279474_-|ATP-binding-protein
MLLLNGRLAGGTYIGVIVLVFILARVTMSGLPYGEGLQAARNTLGEIQKILDAHTLCEPENSAQLTNYALDFHEVSFGYEPSTSVLNNINFHIEPGTTTALVGPSGCGKSTLLKLIVRFYDVDKGMICIGGIDVRELGTRTVLDSLAMVFQDVYLFEDTLYENIRLGRHDATKEEVLHAAELAGVTAIAENLPDGFETLISEGGQNLSGGERQRVSIARAL
>LR134381.1|VEH10226.1|1278550_1278790_-|ATP-binding-protein
MLDEATSSLDIENEHLVMRGLTELSRKRTTIVIAHRLNTIRDADQIVVFGSTGYVEAIGTHEELIEVSPRYRKFWDEKS
>LR134381.1|VEH10225.1|1278341_1278548_+|Uncharacterised-protein
MHDVHYQLFDVKRQHVAISAALISNREIFIFDEPTSATLERMLRFFGRKGSLAVFPAYTCYHIKASNY
>LR134381.1|VEH10224.1|1278203_1278296_-|Uncharacterised-protein
MVTNIYSVVGFKLNAGQRTHAKRNKNIALR
>LR134381.1|VEH10223.1|1277419_1278055_+|hypothetical-membrane-protein
MANFHFVVDKAHAQRNNELLKDTKRLQLSAAIFSFILLAIGAGFYSWLGAMVGVIIFACFTIVALISFILIPVFPRLVGSAQSLYDSYELVPAIITEINPRDMSIMALVDADSTGTNPQPALAVRTISNLAGHSRTVGEKVPSVAVTGNRSAANKQTWDQISPVPIAWGTPEAAIIKAATDAIDPAQWEKLEKHLAHYDEVRKTPFDLLLL
>LR134381.1|VEH10222.1|1275718_1277410_+|UvrABC-system-protein-B
MGPLIVQSDKTVLLETDHEQAAAARAALAPFAELERAPEHVHTYRITPLALWNARAAGYDAENVIDALERFSRFPVAQSLLIDIAEIMSRYGRVRLHMHPAYGLVIESEEPAILAELQRHKKIVPMLGQVIDENYIVVHPSERGRLKQELLKVGWPAEDLAGYVDGEAHPIALSTEHEQWQLRDYQELAAESFWAGGSGVVVLPCGAGKTMVGAAAMAKAQVTTLILVTNTVAGRQWRDELLKRTSLTPEEIGEYSGEKKEIRPVTIATYQVVTRKTKGEYRALELFNSRDWGLIIYDEVHLLPAPVFRMTSDLQSRRRLGLTATLVREDGREGDVFSLIGPKRFDAAWKDLEAQGFIATAECVEVRTTMTDTERMLYATAESNDRYRIAACAHTKIRAMEKILQHHHGQPTLIIGAYVDQLEEIGSHLGIEVIDGKSSTKKRESAFNRFRRGEITTLVVSKVANFSIDLPEATVAIQVSGTFGSRQEEAQRLGRLLRPKADGCAAYFYTLVSRDSIDADYAAHRQRFLAEQGYGYRICSAEDLTTFLPIVTGYPGQSDAEKA
>LR134381.1|VEH10233.1|1289018_1289318_-|Uncharacterised-protein
MRSAIYYLLALVAGACASKINAPWQVFITPLLMALMLVTFAELPIRLEKQSFHYRVMVGNFLVVPLIVAALLWSFRALFDAPAPVLLAAGVVLLSAWIM
>LR134381.1|VEH10234.1|1289317_1290073_-|iron-ABC-transporter-ATP-binding-protein
MITLEKVAKNYNGEVQIGPVSLEIPAGGITALVGPNGAGKSTLLTMIGRLLDLDEGVINVAGFDVSSTKSADLAKVLSILRQENHFITRLTVRQLVGFGRFPYSKGRLTAKDEEIISRYIDFLNLKELENRYLDQLSGGQRQRAYVAMVLCQETDYVMLDEPLNNLDIAHSVEMMKHLAHAAAEFGRTIIVVLHDINFAARYAQHICAVKDGQIVAFGLVEEIMKDEILSDIFNTDITVIDGPGGLLACYH
>LR134381.1|VEH10235.1|1290069_1291137_-|ABC-type-cobalamin/Fe3+-siderophore-transport-system,-permease
MDKAVVTETPALAGFKKEASKNIRRSGAFINARAKLTYWVLFTVITTLALLFAFGLLAYGNPVPFGTPQFWLIAQRRMNAVIAMAVVALCQSLATVAFQTVTNNRIITPSIMGFESLYRALHTSTIFFFGVVGLNNARTLEMFIVQLVLMVGMCLVLYSWLLTGKNSNMHAMLLVGIVIGAGLGSVATFMQRLLTPSEFDVLTARLFGSVNNADPSYYPVAIPLCLTAGILILLSARKLNVLALGKEAAGNLGLNHKRLSIYILVLVSILMATSTALVGPMTFLGFLVVTLTYQLAGTFDHRYLFPMSISLGFLVLTSAYFIMNHVFYAQGVVSIIIEFVGGSAFLIVLLRRGRL
>LR134381.1|VEH10236.1|1291129_1292125_-|FecCD-family-membrane-transport-protein
MIDTSTRESTSTHITRGKLFDVKLIIGIAVVIGLLILSLMTGEYDILNHADGWDIFGIVRIPRTIALVLSGAAMAMSGLVMQLITQNRFVEPTTTGTTEWAGLGLLFCMVVFPSTSVLGRMVCAVLFAFIGTMVFFLFLRKVSLRSSLVVPIIGIMLGAVVSAVSTFFALKTDTLQSLGIWFQGSFTSVYKGQYEVLWIVLFVVLMVFFYADRLTIAGLGEDIATNVGVNYQRMVIIGTGLIAVATGVVTVVVGSLPFLGLIVPNLVSMFRGDDLRSNLPWVCLSGIALVTVCDLLARTLISPFEIPVSVILGMVGAIVFVTLIVRQAKNG
>LR134381.1|VEH10237.1|1292223_1293234_-|periplasmic-binding-protein
MNTKLPKVVALIVATSLTLTACSNSSNSSSSSSESAATSSAAANGTVTVEDNFGTVEIATPVNRVASTDNRTFEVLEQWGIDLVAAPLPLIPSTISYKTDESIVDLGSHREPNLEALVAAEPDLIISGQRFSQHYEAMKTLNPNVPIVDFEPRDGESLDEELKRQVTELGKIFNKESEADQLIADFDAALKRAKQAYNGNDTVMAVNVSGGEIGYIAPSVGRTFGPVFDLLGLKPALEIENASSNHRGDDISVEAIAESNPQWIFVLDRDGAINADKEGYTPALDVIKNNAALANLAVVSDGKIIVAPQDTYTNESIITYTEILNSIADAFEAQKS
>LR134381.1|VEH10238.1|1293551_1294634_+|Threonine-aldolase
MHQPDHIPTTSHIRPHFGNDYHRTAHPRVLEELVATTKETFSGYGLDHRCEQTADLIRHLCHAPQAGVHFMTGGTQVNTTAIAATLRPWQAVISADSGHINVHETGSVEHAGHKILTLAHTLGKITATQISDLVTDYRTSGVSEHASEPKMVYLSQPTEYDTLYSLAELKEIREVCNTFDLFLLIDGARLGYALGSPANDISLAELAQLADMFTIGGTKCGAAFDEAIVFPKPGTDTYFRNNMKQNSGLLAKGWLLGAQFQALMSDNLYVEINAHANKQAQRIAQAFHDAGISLLFPSPTNQQFALLTEQQEQQLSAEFICQFFGTHGNFRVTRFCTSWATEDADIEKLIAAIKRLAPAN
>LR134381.1|VEH10239.1|1294630_1295389_-|3-demethylubiquinone-9-3-methyltransferase
MYAGAMPAITPTAWLNRTADEAADFYVHAFGLVGVDAEIAKTFTYPDPNDHYLAEFAGKTRVKLVRIEDFTLGLINASDEHTTTPAFNLYVSLDKTKAQRLWDILSENGVILVEFSEYTPGIDHGWLTDKFGISWQITTHPDLPTIAPAIHFNGQARQAGDYYLEIFGGTRNEILVEGDELILSSIIIDGQTLVLMDSAVDAIHSAGMSLHLRARGEQQETFHRALSYNPEKDMYGWMEDKFGITWQISDEG
>LR134381.1|VEH10240.1|1296350_1297919_+|type-I-restriction-modification-system,-M-subunit
MTPTDKEGQRAELHKTIWRIANDLRGSVDGWDFKAYVLGMLFYRFISENLTAYINKGEHNAGDEDFDYALLSDENAEYGRAVTVEEKGFYVLPSELFQNVRKRASRDENLNETLERAFKNIEGSAVGTDAEDDLKGLFDDLDVNSSKLGPTVAKRNEKLVKLLDAIGDLPLGNFENNSIDLFGDAYEYLMQMYASQAGKSGGEYYTPQEVSELLARITVHGKTQVNKVYDPAVGSGSLLLKFAKVLGKDNVRQGFYGQEINLTTYNLARINMFLHDVNYEKFDIAHGDTLTDPHHWDDEPFEAIVSNPPYSIKWEGDANPLLINDSRFAPAGVLAPKSKADLAFTMHILSWLAVNGTAAIVEFPGVLYRGGAERKIRKYLIDNNYVDTVIQLPPDLFFGTTIATCIIVLKKSKTDNAVLFIDASAEFSRVGNKNKLLPDNQKQILKHFATREDVEYIAKLVPNEDIAANDYNIAVSSYVEQEDTREVINITELNTEIARIVARQAELRTSIDVIVADLEGTK
>LR134381.1|VEH10241.1|1297915_1299076_+|restriction-modification-system-DNA-specificity-domain-containing-protein
MSRIDELITELCPDGVEFKALGDIAQIVRGNGMPKAVLTDKGVGAIHYGQIYTHYGVWATETLSFVSAETAVKLAKVAPGDIIITNTSENIDDVGKALAWLGVETIVTGGHATVIKHDQEPKYLAYWFASKDFSVQKRKLATGTKVIDVSAKQLAIVRIPVPPLEVQREIVRILDEFTQLEAELEAELEAELEARKKQYEYYRNQLLTFPETGGEFKMLGKVLQIKNGKDHKLLGDGSIPVYGSGGIMRYVNTAAAEGPSVLIPRKGSLGNIFYVEGPFWIVDTIFRTEIDLSQVEPKFVYYLLLTMRLNEMNQAAGVPSQTQAVLNSLRIPVPPLEIQKKIVAILDRFETLIEDISVGLPAEISARRKQYEYYRDKLLTFKEATA
>LR134381.1|VEH10242.1|1299072_1302198_+|type-I-site-specific-deoxyribonuclease,-HsdR-family-protein
MNEATPRKYDPIAVSSESTVVAEYIPDAKKDGAYQSEAALEREMIRLLESQAYEYLPLTSEAQLVSNLRAQLEALNHITFSDTEWRDFFENVIAGKNDGIIEKTVRIQEDHVQLLKRDDGSTKNITLLDKQNIHNNRLQVINQYEVDRADPTDKGNSGGRYANRYDVTVLVNGLPMVHVELKRRGVDIREAFNQIDRYQRDSFWADSGLFEYVQLFVISNGTLTKYYSNTTRSQCLKESQKSGTGKKTSNSFEFTSWWADAQNKPIQDLTSFIKTFFTKHTLLSILTKYCVLTADRMLLVMRPYQIIATERILQRIDTATNYERLGTVDAGGYVWHTTGSGKTLTSFKTAQLSSALPSVDKVLFVVDRKDLDYQTIREYDRFQKGAANSNTSTAVLKRQLEDPGTRIIITTIQKLSTFIKANKKHAVYDQHVVIIFDECHRSQFGDMHTDIIQSFQRYNIFGFTGTPIFTANSGSGGNPQLKTTEQAFGEKLHTYTIVDAITDKNVLPFRIDYVSTIKVGTVIDKQVSAIDAEKALLDPKRIDDIVRYTLEHFDQKTKRSSSYEHSVVMNVTEATRTRRQAEALRERKRVRGFNAIFATASIDAARRYYNAFQTQQEQLPPDKRLKIGLIYSYGANEAADDGILDDEAFDTGSLSLDARGFLEDAIQDYNDLFGTSYDTSADRFQNYYKDLSQRLKNRELDLVIVVNMFLTGFDATTLNTLFVDKNLRAHGLIQAYSRTNRILNSVKTYGNIVAFRDLEEETTAALELFGNKDSCGVVLLKPYSDYYDEYAEKVTELLKSFPLGEQIVGESAQKDFIQLFGAILRLENILTSFDDFAGHEMLTERQGQDYRSLYLDLYAEFRKEKTAEKELINDDVVFEIELIKQVEINVDYILMLVAKHREQFGDGQNKEIRSEISRAIDASPTLRSKKDLIEAFVDAVSADGAIDDEWQAFIAAKREEELALIIEEENLCADATREFIKIAFRDGVLRTTGTEITKMLPPVSRFAASGGHSEKKQRVIQKFNAFFKRFFELTTKGETDA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134381_1	1.2\|311326\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	311326-311358	33	NZ_KU306397	Corynebacterium glutamicum strain DSM 1412 plasmid pBL90, complete sequence	11844-11876	4	0.879
LR134381_1	1.11\|311875\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	311875-311907	33	MT362618	Microcystis phage MaeS, complete genome	34860-34892	7	0.788
LR134381_1	1.11\|311875\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	311875-311907	33	NC_041877	Pseudomonas phage SM1, complete genome	26934-26966	7	0.788
LR134381_1	1.11\|311875\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	311875-311907	33	JQ067090	UNVERIFIED: Pseudomonas phage PaMx31, partial genome	50932-50964	7	0.788
LR134381_1	1.11\|311875\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	311875-311907	33	NZ_AP014659	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6a, complete sequence	111189-111221	8	0.758
LR134381_1	1.11\|311875\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	311875-311907	33	NZ_CP049701	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence	39005-39037	8	0.758
LR134381_1	1.15\|312119\|33\|LR134381\|CRISPRCasFinder,CRT,PILER-CR	312119-312151	33	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	491172-491204	10	0.697
LR134381_3	3.1\|316357\|33\|LR134381\|PILER-CR,CRISPRCasFinder,CRT	316357-316389	33	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	704029-704061	11	0.667

1. spacer 1.2|311326|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KU306397 (Corynebacterium glutamicum strain DSM 1412 plasmid pBL90, complete sequence) position: , mismatch: 4, identity: 0.879

acggcggctgatctaccatgtcaaaccacgaat	CRISPR spacer
caggcggctggtctaccgtgtcaaaccacgaat	Protospacer
  ********.******.***************

2. spacer 1.11|311875|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to MT362618 (Microcystis phage MaeS, complete genome) position: , mismatch: 7, identity: 0.788

tacaccaacagcctcaaaagcatcagcgatacc	CRISPR spacer
ttcacctacagcatcaaaagcatcagcattaaa	Protospacer
* **** ***** **************. **

3. spacer 1.11|311875|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to NC_041877 (Pseudomonas phage SM1, complete genome) position: , mismatch: 7, identity: 0.788

tacaccaacagcctcaaaagcatcagcgatacc-	CRISPR spacer
cacaccagcagcatcaaaagcatcaa-gattcaa	Protospacer
.******.**** ************. *** *

4. spacer 1.11|311875|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to JQ067090 (UNVERIFIED: Pseudomonas phage PaMx31, partial genome) position: , mismatch: 7, identity: 0.788

tacaccaacagcctcaaaagcatcagcgatacc-	CRISPR spacer
cacaccagcagcatcaaaagcatcaa-gattcaa	Protospacer
.******.**** ************. *** *

5. spacer 1.11|311875|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014659 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6a, complete sequence) position: , mismatch: 8, identity: 0.758

tacaccaacagcctcaaaagcatcagcgatacc	CRISPR spacer
cacaccaacagcctctacagcatcagcgcgcgg	Protospacer
.************** * **********

6. spacer 1.11|311875|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP049701 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence) position: , mismatch: 8, identity: 0.758

tacaccaacagcctcaaaagcatcagcgatacc	CRISPR spacer
cacaccaacagcctctacagcatcagcgcgcgg	Protospacer
.************** * **********

7. spacer 1.15|312119|33|LR134381|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

aggcgcatcacagatcaagatgtcgccgacgcc	CRISPR spacer
gtcggcatcaccgatcacgatgtcgccggggtt	Protospacer
.   ******* ***** **********. *..

8. spacer 3.1|316357|33|LR134381|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 11, identity: 0.667

cggtcagtatcgacaggcttgaagggcgcgctc	CRISPR spacer
tcgtcagtatcgacaggttggaagggaaaaggg	Protospacer
. ***************.* ****** . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

357778 : 378695

Corynebacterium_phage(45.0%)

integrase,terminase

attL 360288:360301|attR 363247:363260

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEH09392.1\|357778_360457_-	DNA polymerase I	F8WQ35	Bacillus_phage	2.5e-48	33.9
360288:360301	attL	NA	NA	NA	NA
VEH09393.1\|360717_361833_-\|integrase	putative phage-related integrase	A0A1W6JQG4	Corynebacterium_phage	6.1e-73	39.2
VEH09394.1\|362556_363009_-	ribosomal protein S13	A0A0K0N6E3	Gordonia_phage	6.2e-16	40.8
VEH09395.1\|363201_363609_+	putative anti-repressor protein	A0A2R2ZGJ4	Clostridioides_phage	2.4e-27	53.2
363247:363260	attR	NA	NA	NA	NA
VEH09396.1\|363625_363898_+	phage-associated protein	A0A1W6JQ97	Corynebacterium_phage	1.2e-11	59.0
VEH09397.1\|364081_364774_+	phage-associated protein	A0A1W6JQ97	Corynebacterium_phage	2.7e-79	61.5
VEH09398.1\|364935_365202_+	phage protein	M9QRS1	Staphylococcus_phage	1.5e-06	42.0
VEH09399.1\|365328_365550_+	Protein of uncharacterised function (DUF2815)	NA	NA	NA	NA
VEH09400.1\|365621_365768_-	Uncharacterised protein	NA	NA	NA	NA
VEH09401.1\|366121_366487_+	putative DNA-directed DNA polymerase	A0A1B0RXB4	Streptococcus_phage	3.9e-21	44.4
VEH09402.1\|366739_367504_+	putative DNA-directed DNA polymerase	A0A1W6JQ98	Corynebacterium_phage	2.4e-84	67.9
VEH09403.1\|367464_367614_+	putative DNA-directed DNA polymerase	D2J043	Enterococcus_phage	1.6e-05	42.9
VEH09404.1\|368118_369105_+	virulence-associated E family protein	A0A1W6JQ82	Corynebacterium_phage	2.9e-87	51.7
VEH09405.1\|369224_369506_+	virulence-associated E family protein	A0A1W6JQ82	Corynebacterium_phage	9.1e-26	80.0
VEH09406.1\|369622_370087_+	virulence-associated E family protein	A0A1W6JQ82	Corynebacterium_phage	1.3e-37	50.3
VEH09407.1\|370666_371494_+	phage-associated protein	A0A1W6JQF1	Corynebacterium_phage	2.8e-22	73.9
VEH09408.1\|371450_372005_+	phage-associated protein	A0A1L6BZE2	Pasteurella_phage	2.5e-67	71.2
VEH09409.1\|372001_372334_+	Uncharacterised protein	NA	NA	NA	NA
VEH09410.1\|372366_372525_+	Uncharacterised protein	NA	NA	NA	NA
VEH09411.1\|372587_372767_+	Uncharacterised protein	NA	NA	NA	NA
VEH09412.1\|373905_374013_+	Uncharacterised protein	NA	NA	NA	NA
VEH09413.1\|374066_374318_+	Uncharacterised protein	A0A162E1R7	Tsukamurella_phage	3.1e-09	55.9
VEH09414.1\|374289_374445_+	Uncharacterised protein	NA	NA	NA	NA
VEH09415.1\|374493_375354_+\|terminase	putative phage terminase	A0A2P1A0R0	Gordonia_phage	4.5e-76	64.7
VEH09416.1\|375314_376064_+	Uncharacterised protein	A0A159B6M5	Tsukamurella_phage	1.9e-70	55.0
VEH09417.1\|376063_377500_+	gene 14 protein	A0A159B6N0	Tsukamurella_phage	4.6e-81	41.4
VEH09418.1\|377519_378695_+	Uncharacterised protein	A0A220NQN8	Corynebacterium_phage	1.2e-15	30.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134381

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection