CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134495	Mannheimia haemolytica strain NCTC10643 genome assembly, chromosome: 1	1 crisprs	cas2,csa3,cas3,PD-DExK,DEDDh,cas5,cas8c,cas7,cas4,cas1,DinG	0	5	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134495_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134495_1

1219562-1220594

TypeI

Consensus_repeat	Method
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	PILER-CR
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CRISPRCasFinder
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CRT

15 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of LR134495_1

>merge|LR134495|1|1219562-1220594|PILER-CR,CRISPRCasFinder,CRT
GCAGCCACCTACGCGTGGCTGTGAATTGAAACGATTAGGCGGAAAGGGGATTGTTAAAAAGCCTAGGCAGCCACCTACGCGTGGCTGTGAATTGAAACAGCAAACCGCTCCCTTAACCCTTCGGGCAACTTTGCAGCCACCTACGCGTGGCTGTGAATTGAAACTATCTATATTGGTAATAAAGGTACTAATATGTGGGCAGCCACCTACGCGTGGCTGTGAATTGAAACCCTACTGAAATAGTTTGGATAGAAGAAAATACTGCAGCCACCTACGCGTGGCTGTGAATTGAAACTAATTCCAATACACCTCTCCAGATTATTGTAAGATGGCAGCCACCTACGCGTGGCTGTGAATTGAAACACTAGTGACTAGTGAAGTAAGTTCACACACAAAAGCAGCCACCTACGCGTGGCTGTGAATTGAAACATTTCCATGATTTAAGGCATACTTGGGCCAGTTGGGCAGCCACCTACGCGTGGCTGTGAATTGAAACGACCATATTCAAACGCATTGCCGTAGTATTGATGCAGCCACCTACGCGTGGCTGTGAATTGAAACCATACGGCTTGCGTAACGATTTAAGCCGGTTTTGCAGCCACCTACGCGTGGCTGTGAATTGAAACCCTCTTTCGGAATATGGCACCTCGATACATCAGAAGCAGCCACCTACGCGTGGCTGTGAATTGAAACCGCATTTGCTACTTTCTGAGCACCACCAGTATGAGCGCAGCCACCTACGCGTGGCTGTGAATTGAAACAAAACACCCACGCAGGGTTATTTGTCCACGCTTGTTTCCGCAGCCACCTACGCGTGGCTGTGAATTGAAACGTGTGGTGTGCGTGCTGAACCTTGTTTTTTACCGCCGCAGCCACCTACGCGTGGCTGTGAATTGAAACCATCACTTCACCTCCTGCTCAAACGGCTGGATAATGCAGCCACCTATGCGTGGTTGTGTATTGAAACTTACAAGATGCTGAAGTAGTTAAATCAATAGCACGTAGCCATCTTCGCATCGATATATATTGAAAT

>LR134495|1|1|1219562-1220461|PILER-CR
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GATTAGGCGGAAAGGGGATTGTTAAAAAGCCTAG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	AGCAAACCGCTCCCTTAACCCTTCGGGCAACTTT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	TATCTATATTGGTAATAAAGGTACTAATATGTGG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CCTACTGAAATAGTTTGGATAGAAGAAAATACT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	TAATTCCAATACACCTCTCCAGATTATTGTAAGATG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	ACTAGTGACTAGTGAAGTAAGTTCACACACAAAA
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	ATTTCCATGATTTAAGGCATACTTGGGCCAGTTGG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GACCATATTCAAACGCATTGCCGTAGTATTGAT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CATACGGCTTGCGTAACGATTTAAGCCGGTTTT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CCTCTTTCGGAATATGGCACCTCGATACATCAGAA
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CGCATTTGCTACTTTCTGAGCACCACCAGTATGAGC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	AAAACACCCACGCAGGGTTATTTGTCCACGCTTGTTTCC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GTGTGGTGTGCGTGCTGAACCTTGTTTTTTACCGCC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC

>LR134495|1|1|1219562-1220594|CRISPRCasFinder
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GATTAGGCGGAAAGGGGATTGTTAAAAAGCCTAG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	AGCAAACCGCTCCCTTAACCCTTCGGGCAACTTT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	TATCTATATTGGTAATAAAGGTACTAATATGTGG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CCTACTGAAATAGTTTGGATAGAAGAAAATACT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	TAATTCCAATACACCTCTCCAGATTATTGTAAGATG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	ACTAGTGACTAGTGAAGTAAGTTCACACACAAAA
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	ATTTCCATGATTTAAGGCATACTTGGGCCAGTTGG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GACCATATTCAAACGCATTGCCGTAGTATTGAT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CATACGGCTTGCGTAACGATTTAAGCCGGTTTT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CCTCTTTCGGAATATGGCACCTCGATACATCAGAA
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CGCATTTGCTACTTTCTGAGCACCACCAGTATGAGC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	AAAACACCCACGCAGGGTTATTTGTCCACGCTTGTTTCC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GTGTGGTGTGCGTGCTGAACCTTGTTTTTTACCGCC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CATCACTTCACCTCCTGCTCAAACGGCTGGATAAT
GCAGCCACCTATGCGTGGTTGTGTATTGAAAC	TTACAAGATGCTGAAGTAGTTAAATCAATAGCAC
GTAGCCATCTTCGCATCGATATATATTGAAAT

>LR134495|1|1|1219562-1220528|CRT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GATTAGGCGGAAAGGGGATTGTTAAAAAGCCTAG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	AGCAAACCGCTCCCTTAACCCTTCGGGCAACTTT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	TATCTATATTGGTAATAAAGGTACTAATATGTGG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CCTACTGAAATAGTTTGGATAGAAGAAAATACT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	TAATTCCAATACACCTCTCCAGATTATTGTAAGATG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	ACTAGTGACTAGTGAAGTAAGTTCACACACAAAA
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	ATTTCCATGATTTAAGGCATACTTGGGCCAGTTGG
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GACCATATTCAAACGCATTGCCGTAGTATTGAT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CATACGGCTTGCGTAACGATTTAAGCCGGTTTT
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CCTCTTTCGGAATATGGCACCTCGATACATCAGAA
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CGCATTTGCTACTTTCTGAGCACCACCAGTATGAGC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	AAAACACCCACGCAGGGTTATTTGTCCACGCTTGTTTCC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	GTGTGGTGTGCGTGCTGAACCTTGTTTTTTACCGCC
GCAGCCACCTACGCGTGGCTGTGAATTGAAAC	CATCACTTCACCTCCTGCTCAAACGGCTGGATAAT
GCAGCCACCTATGCGTGGTTGTGTATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134495.1\|VEI77133.1\|1226957_1227359_-\|H-NS-homolog-stpA	unknown	unknown	gnl\|CDD\|182380
LR134495.1\|VEI77108.1\|1211978_1212788_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134495.1\|VEI77118.1\|1216830_1217994_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|293817
LR134495.1\|VEI77139.1\|1231831_1232638_+\|Tryptophan-synthase-alpha-chain	unknown	unknown	gnl\|CDD\|161792
LR134495.1\|VEI77137.1\|1230639_1231830_+\|Tryptophan-synthase-beta-chain	unknown	unknown	gnl\|CDD\|235288
LR134495.1\|VEI77129.1\|1225328_1226012_+\|vancomycin-high-temperature-exclusion-protein	unknown	unknown	gnl\|CDD\|225500
LR134495.1\|VEI77104.1\|1208895_1211184_+\|Superfamily-II-helicase	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
LR134495.1\|VEI77106.1\|1211246_1211978_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134495.1\|VEI77122.1\|1219076_1219370_+\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
LR134495.1\|VEI77136.1\|1229553_1230306_+\|NADP-dependent-3-hydroxy-acid-dehydrogenase-YdfG	unknown	unknown	gnl\|CDD\|187604
LR134495.1\|VEI77110.1\|1212790_1213468_+\|CRISPR-associated-protein-Cas5,-subtype-I-C/DVULG	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
LR134495.1\|VEI77120.1\|1217996_1219010_+\|CRISPR-associated-endonuclease-Cas1,-subtype-I-C/DVULG	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
LR134495.1\|VEI77135.1\|1227795_1229328_+\|Malate-2H(+)/Na(+)-lactate-antiporter	unknown	unknown	gnl\|CDD\|224671
LR134495.1\|VEI77124.1\|1220778_1222254_+\|Ribonuclease-G	unknown	unknown	gnl\|CDD\|183285
LR134495.1\|VEI77128.1\|1223987_1225061_-\|Homoserine-O-acetyltransferase	unknown	unknown	gnl\|CDD\|234678
LR134495.1\|VEI77116.1\|1216115_1216790_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
LR134495.1\|VEI77126.1\|1222407_1223910_+\|Lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
LR134495.1\|VEI77131.1\|1226048_1226888_-\|Formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
LR134495.1\|VEI77114.1\|1215252_1216116_+\|Uncharacterized-protein-predicted-to-be-involved-in-DNA-repair	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
LR134495.1\|VEI77112.1\|1213464_1215243_+\|CRISPR-associated-protein-Cas8c/Csd1,-subtype-I-C/DVULG	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|187887

Protein	Function_ID	Function_description	E-value
LR134495.1\|VEI77137.1\|1230639_1231830_+\|Tryptophan-synthase-beta-chain	gnl\|CDD\|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
LR134495.1\|VEI77118.1\|1216830_1217994_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|293817	cd07731, ComA-like_MBL-fold, Competence protein ComA, ComEC and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes proteins required for natural transformation competence including Neisseria gonorrhoeae ComA, Pseudomonas stutzeri ComA, Bacillus subtilis ComEC (also known as ComE operon protein 3) and Haemophilus influenza ORF2 encoded by the rec-2 gene, as well as Escherichia coli YcaI which does not mediate spontaneous plasmid transformation on nutrient-containing agar plates. It also includes the phosphorylcholine esterase (Pce) domain of choline-binding protein e from streptococcus pneumonia. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. .	1.26587e-05
LR134495.1\|VEI77139.1\|1231831_1232638_+\|Tryptophan-synthase-alpha-chain	gnl\|CDD\|161792	TIGR00262, Tryptophan_synthase_alpha_chain, tryptophan synthase, alpha subunit. Tryptophan synthase catalyzes the last step in the biosynthesis of tryptophan. The alpha chain is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. In bacteria and plants each domain is found on a separate subunit (alpha and beta chains), while in fungi the two domains are fused together on a single multifunctional protein. The signature pattern for trpA contains three conserved acidic residues. [LIVM]-E-[LIVM]-G-x(2)-[FYC]-[ST]-[DE]-[PA]-[LIVMY]-[AGLI]-[DE]-G and this is located between residues 43-58 of the model. The Sulfolobus solfataricus trpA is known to be quite divergent from other known trpA sequences. [Amino acid biosynthesis, Aromatic amino acid family].	9.65189e-122
LR134495.1\|VEI77129.1\|1225328_1226012_+\|vancomycin-high-temperature-exclusion-protein	gnl\|CDD\|225500	COG2949, SanA, Uncharacterized membrane protein [Function unknown].	8.6122e-75
LR134495.1\|VEI77104.1\|1208895_1211184_+\|Superfamily-II-helicase	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	8.3245e-59
LR134495.1\|VEI77133.1\|1226957_1227359_-\|H-NS-homolog-stpA	gnl\|CDD\|182380	PRK10328, PRK10328, DNA-binding protein StpA.	1.88801e-33
LR134495.1\|VEI77126.1\|1222407_1223910_+\|Lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
LR134495.1\|VEI77136.1\|1229553_1230306_+\|NADP-dependent-3-hydroxy-acid-dehydrogenase-YdfG	gnl\|CDD\|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.49996e-147
LR134495.1\|VEI77110.1\|1212790_1213468_+\|CRISPR-associated-protein-Cas5,-subtype-I-C/DVULG	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	6.7529e-114
LR134495.1\|VEI77120.1\|1217996_1219010_+\|CRISPR-associated-endonuclease-Cas1,-subtype-I-C/DVULG	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
LR134495.1\|VEI77135.1\|1227795_1229328_+\|Malate-2H(+)/Na(+)-lactate-antiporter	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	5.34149e-96
LR134495.1\|VEI77124.1\|1220778_1222254_+\|Ribonuclease-G	gnl\|CDD\|183285	PRK11712, PRK11712, ribonuclease G; Provisional.	0
LR134495.1\|VEI77128.1\|1223987_1225061_-\|Homoserine-O-acetyltransferase	gnl\|CDD\|234678	PRK00175, metX, homoserine O-acetyltransferase; Provisional.	0
LR134495.1\|VEI77116.1\|1216115_1216790_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.55788e-42
LR134495.1\|VEI77122.1\|1219076_1219370_+\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.92971e-32
LR134495.1\|VEI77131.1\|1226048_1226888_-\|Formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	2.21496e-173
LR134495.1\|VEI77114.1\|1215252_1216116_+\|Uncharacterized-protein-predicted-to-be-involved-in-DNA-repair	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.34982e-154
LR134495.1\|VEI77112.1\|1213464_1215243_+\|CRISPR-associated-protein-Cas8c/Csd1,-subtype-I-C/DVULG	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	0

>LR134495.1|VEI77122.1|1219076_1219370_+|CRISPR-associated-endoribonuclease-Cas2
MLMLITYDISFDDPEGQARLRRIAKHCLDYGVRAQYSVFECDVTPAQWVTLKNKLLTTYNPDCDSLRFYHLGSKWRNKVEHHGAKPSVDIFKDTLIL
>LR134495.1|VEI77120.1|1217996_1219010_+|CRISPR-associated-endonuclease-Cas1,-subtype-I-C/DVULG
MRKLQNTLYITTQGSYLHKERETLVVEQDRKKVAQLPIHSIGHIFCFGNVLVSPFLMGFCGENNVNLAFFTENGRYLGRLQGRQSGNVLLRRAQYKKSETNPVPVARNIIAAKIQASKRVLQRQIRNHGENADLQSTITALNYSLQQLKTADNLDLIRGIEGDAAARYFGVFSHLIKENSGFHFDGRNRRPPRDGVNALLSFLYSIVGKDISGALQGVGLDPQIGFLHADRPGRDSLAQDILEEFRAWWVDRMVLSLINRGQVKPDDFVTEASGAVTLKPEARKLLFQTLQAKKQEKIIHPFLEEEVEIGLLPYIQAMLLARHLRGDLAEYPPFLMR
>LR134495.1|VEI77118.1|1216830_1217994_+|DNA-internalization-related-competence-protein-ComEC/Rec2
MDIKLIRSFHAVGQGAFYSERFINDSNIAFNVVYDCGAMPKSKVIDRVIKESFKESDDIDILFISHFDSDHVNGIEILKKNRNIKRVVMPLLAEKEKFFLINLYKSLGGTYNHSLVKLIENPEVFFGEDTKVIQVKSININDRDLADNNDSEIKHIMDISSINGSISSGTPISFKLSDTFFWVYYPYNYKYSNRRCQFIQEITKKGITEENLADPEFVSNSKNQIIIRTAYKSKAVDGSINENSMLVCSCPMKISIVKYMDNYQGYFPLYLSSYFLWDEVNPGCIYTGDSDLKVIASDLLNKINNIKSNIGTIQVAHHGSHNNFYVNFFNQFGEFLICPISFGTKNTYGHPSYIVLSELFCHKHIPVCVTEQRGSSFFQRFDISLEQ
>LR134495.1|VEI77116.1|1216115_1216790_+|CRISPR-associated-protein-Cas4
MDDLQHSAEILPLVPPTLGDDKRLISLSALQHYAFCPRQCALIHNEQAWAENFLTAQGKALHERVDSGEPETRKGIRFERTVHVAAEKLGISGILDLVERDLKTGELKPVEYKRGKPKLEPMDEIQLCAQALCLEEMTGQTINEGALWYMQTRHRLPIIFSPELRTKTLATIAEVRSLLNSGTTPLPKYSKRCKACSLIDLCQPQLLERDRSKGYVVGVFGEKK
>LR134495.1|VEI77114.1|1215252_1216116_+|Uncharacterized-protein-predicted-to-be-involved-in-DNA-repair
MSIQNRYEFVFFFDVTNGNPNGDPDAGNMPRLDPETSKGLVTDVCLKRKIRNFIEMSYENEAGYEIYVKEKSVLNLQNKRAYEALGIESEAKKLPKEEAKAREITAWMCKNFFDIRTFGAVMTTEVNSGQVRGPVQLAFAQSIDPIIPLEVSITRMAVTNEKDLEKERTMGRKYIVPYALYRVHGFISAKLAEKTGFSDEDVQKLWQALQLMFEHDRSAARGEMAARKLIVFKHDSELGNQPAHKLFETVKVERVNGEKDTPAKGYDDYRISVQAEGLNGVTVEELL
>LR134495.1|VEI77112.1|1213464_1215243_+|CRISPR-associated-protein-Cas8c/Csd1,-subtype-I-C/DVULG
MILSALTRYYYRLAAQEDRSTGEAKVPSYGFSEEKIGWVLELDSKGNLVNVIPNLTADKKPKPKLMSVPRPEKRTSGIKPNFLWDKTAYVLGVESNQDKATAKDQPINFAEKTFEAFKQYHLDLLADSNDEGLVAIKNFLQQWQPEHFAESICPIEILDANVVFKLVGTSGYIHQREAAQSLWGRLLVSEESEQGLCLISGEIAPIARLHPAIKGVYGGQSAGGSIISFNKESFTSFGKEQGSNAPVSEQAAFAYTTALNYLLRTEKHRLTIGDASTVFWAEADNTTQAEAAEGFFAALMTPPDDDQENQKIFDELQKISKGRPLAEISPELSENTRFYVLGLAPNAARISVRFWLDTTFGQLAKNLSEHWQDLALEPCAWKTPPSIWRLLLQTASLGKSENISPVLAGEMARAVISGHLYPMSLLSQLVTRIRADGDINGLRVALMKAVLQRKFRKGFIKEGVPMSLNKESDNQAYLLGRLFAVLERIQTQALGELNAGIADRYYGSASAVPFSVFPRLLSGAKHHLSRLRKDKGGMAVNLDKDLGEIIASLPENFPRHLNIDEQGRFAIGYYHQKQSYFAKKETTESIEN
>LR134495.1|VEI77110.1|1212790_1213468_+|CRISPR-associated-protein-Cas5,-subtype-I-C/DVULG
MPNKIKLHIWGDYACFTRPEMKVERVSYDVITPSAARGILAAVHWKPAMRWVIDKIYVLKPIQFESVRRNELGSKISATKISGAMKRKTVADLYTVIEDDRQQRAATVLKNVGYVIEAHAVLTKMAGEAETVTKHIEMFKRRAKKGQCFQQPCMGVREFAANFALIDDDEPLPECFLAENEQDRDLGWMLHDIDFEHGNQPRFFRAEMKNGVIDVPPFYAEEVKS
>LR134495.1|VEI77108.1|1211978_1212788_+|Uncharacterised-protein
MKNEDDLIKFLQAYQTYLTSSFSELWDMVEIEYDKLEAYSVIGGLLSRQVTLSIQMARSPNTLNVHVAPLFLRAMTDLHITLAWIMLDLEERSKKYILYGLGEEKLLVEHYKKGISNSPDNPDNEQIMKLIDFKLNWINSQRRDFFVEVNLGHWAQLDYRKMAQESGCEDLYKFAYKPFSHGAHNMWPHISIYNCKYCESPLHKHHLIPALFEVPLELDFLFRSCKYIDKAYKLFIDKFGLRLNMLPLEWWNSYFTGQESITDDEIKGK
>LR134495.1|VEI77106.1|1211246_1211978_+|Uncharacterised-protein
MNKAECQKKVLKDHKKIGQTLIPPLMQLPNLQETSFREESLPSLIWISAIFLRCSDKEAVENIVHFITKCNEILNDEKKLALVFINNFNCLNNDQKEKIRVGIGDYMLNFLRKMLEHHHFLFSDYPLDFLFDNYDFQITKNDAVSLLKEDISALLDRYNMHATKVQTTAFYSMAVTGQIVFGPDIDMPNLNAILTAPESDESKRVGAFVRASLNGVNSFDSVSGKEDWAKLFWKQCFNMEACS
>LR134495.1|VEI77104.1|1208895_1211184_+|Superfamily-II-helicase
MEEHTIQSFYAHSGKLSDHSDWQTLLSHANNVGLLAAEFAVPFASQEIARCTGLLHDLGKYSERYQKRLHGGERVNHSTAGAKIAVERWGPLGKMMAFCIAGHHAGLANGSGEGKNRSTLTQRLQEQFGYGHKDLPVLDAIWQQELNLPEKLPLPPLKPSKNEPFFSYAFFIRMLYSCLVDADFLDTEAFYANLEKRPLERGNYPNLTALHQQFNQFIAQFRERITIQTPNTQETQCKAEVNRLRSEILDYAVSQAKQETGLFSLTVPTGGGKTFTSMAFALEHAKQHGLRRIIYVIPFTSIIEQNAAEFRKAFGELGTEAVLEHHSTFDHDSLPDKSSRDKLKLASENWDAPIVVTTAVQFFESLFADRSSRCRKLHNIAGSVIILDEAQMLPLNLLRPIMAAIDELARNYQCSVVLCTATQPAIHQVNGFYKGFENVREIAPNPTALFEKLKRTTVKHIGIQTDVELQSKLADNSQMLIIVNNRRHARALYDSAKQLEGAYHLTTLMCAKHRSQTLTEIRLRLKQNLPCRVIATSLIEAGVDVDFPLVMRAEAGLDSVAQAAGRCNREGKRLAVESNVWVFQPEEQWKAPPELGLLSGCMRSTVQVHAEDLLTPQAINHYFQAVYEAKGKELDKPNILKACHDAGQSLNFPFQNIAEDFRMITSHLIPVIIPFDQEAENLIDRLRYADQVGGILRKLQPYTVQIPEKALAELCNAGRVETINETNFGKQFYCLIGMDLYDEVAGLSWEDVGFLREESLVL
>LR134495.1|VEI77124.1|1220778_1222254_+|Ribonuclease-G
MSSTELLVNVTPSETRVALVENGILKELHIEREAKRGIVGNIYKGRVTRVLPGMQSAFVDIGLEKAAFLHASDIVSHTECVDENEKKQFLVKDISELVREGQDIVVQVVKDPIGTKGARLTTDITLPSRYLVFMPENSHVGVSQRIESEEERARLKSLVEPYCDELGGFIVRTAAEEATEESLKQDVEFLKRLWRKVLERKGKYSAKSMLYGELALAQRVLRDFIGTHINSVRIDSKLTYEQVREFLAEFMPELTDCVTLYTGQQTLFDAYGVEKAIQKALDKRVDLKSGGYLIIEQTEAMTTIDINTGAFVGHRNLAHTIFNTNIEATQAIAHQLQLRNLGGIIIIDFIDMQEEEHRERVLQSLKEALKGDRVKTNVNGFTQLGLVEMTRKRTRESLERILCCDCPACRGRGTVKTVETVCYEIMREVVRVHHLFKTDKINVYASKEVAEYLINEESHALLAEVQAFIGKKIEVKLEPYYHQEQFDVVVM
>LR134495.1|VEI77126.1|1222407_1223910_+|Lysine--tRNA-ligase
MSEVENQELDLNGEMLARREKLNKIREQGNAFPNTFRRDALAKDLHAQYDAVEGETLKEQNIQVKVAGRVMLKRVMGKASFFTIQDVSGAIQLYVARDNLSDNVYEEKVSLWDLGDIVGVEGTLFKTKTGELTVRCSEVQLLTKSLRPLPDKHHGLTDLETRYRQRYLDLISNEESRRTFMIRSQVVSGIRKFFLERDFIEVETPMLQVIPGGAAAKPFITHHNALDVDMYLRIAPELYLKRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMIEYYQAYADYHDLMDNTEELLRQLALDILGTTDVPYGDYVFDFGKPFERITMHDAIVKYGNGIQREDLDSFEKSVEIAKGLGIEIQKSWGLGSVVNAIFEEVAEHQLIQPTFLMAHPAEISPLARRNDENPEVTDRFELFIGGREIGNGFSELNDAEDQAERFDAQVAAKDAGDDEAMFKDEDFIVALEHGLPPTAGEGLGIDRLAMIFANAPSIRDVILFPAMRQK
>LR134495.1|VEI77128.1|1223987_1225061_-|Homoserine-O-acetyltransferase
MAQQITLFEDVPLPLTLGGELSPITVAYQTYGRLNAEKSNAVLLCHALTGDAEPYYDSPTEKGWWQDFIGKGLAFDTDKYFFICSNVLGGCKGTTGPASINPKTNKPYGSLFPIITVQDIVNVQKALLDYLEIPQLHAVVGGSFGGMQATQWGISYPDKVRNIINLCSSLILSAEAIGFNHVMRQAIINDPHFNGGNYYDGIAPDNGLKIARMLGMLTYRTDIQLAKAFGRETKQQGQIWGDHFQVESYLSYQGTKFLGRFDANTYLRLLRALDLYDPALGYENEETALKRIKANYTFVAVTSDQLFKQIDVYKSKQKLEQAGVNLEFHEFNSDFGHDAFLVDYDFFEPMIKAGLAK
>LR134495.1|VEI77129.1|1225328_1226012_+|vancomycin-high-temperature-exclusion-protein
MNQTRDRLEKLPLFHKMQQFIIKALKIIAIFPLLGIAILLVVDSLTSYIVRDKIYTDSKQIPYREYAVVLGTAKFYSKDVINQYYKYRLEAAKQLVQEGKVNQLLLSGDNKTPYYNEPKTMTSDLLKMGIATSKIKQDYAGYTTFDSIIRAKKVYKLPPFTIISQKFHCERALFIAKFRDIDAICYAATYPEGAYQVRMREILARSAMVFSLLIGKEPESLEDIRSK
>LR134495.1|VEI77131.1|1226048_1226888_-|Formyltetrahydrofolate-deformylase
MLQQHKILLTECPDDTGLVAKITNICYKHQLNIIKNSEFVENETKRFFMRTELNGIFNDETLLADLKFTLPEGSSYKLLPKQRKRIVILVTKEAHCLGDLLMKNYYGGLDVEIAAVIGNHETLKSLVERFDIPFHLVSHENLTRVEHDKLLAEKIDEYSPDYIVLAKYMRVLNPEFVARYPNRVVNIHHSFLPAFIGAKPYHRAYERGVKIIGATAHFVNDELDEGPIIMQNVINVDHTYTAEAMMRAGRDVEKTVLSQALELVLADKVFVYKNKTIIL
>LR134495.1|VEI77133.1|1226957_1227359_-|H-NS-homolog-stpA
MSALKSLLNIRSLRALAKDLALEQLKSISEKLDIIIAEKEEEMKQEELEKLKQLESLNKYREMLKQDGLSIDELAELLADKVIKARKALSPRPAKYKFVDANGNEKTWTGQGRTPKALQDALDSGKKLEDFAI
>LR134495.1|VEI77135.1|1227795_1229328_+|Malate-2H(+)/Na(+)-lactate-antiporter
MNLVDYSTSLWSVLPALIALILAIVTRKVIISLSIGILFGAFMLTNSNFLDALTYIKNSVVSLVYKGAEEGLNSNNVNIILFLLLLGVLTSLLSISGSNQAFANWAQKKVKGKRGAKLMAAGLVFFTFIDDYFHSLAVGAIARPVTDKFRVSRAKLAYILDSTAAPMCVLMPISSWGAYIITLIAGLLATHSITGYSPLGAFMTMSAMNFYAIFAMIMVFFVAYFSFDIGSMARFERQAAHLAELDDEQIETKGHVRDLILPIIALIVATVSMMMKTGADALAESGASFSILGAFENTTVGISLVVGGVAGLIVATICIITSGNISFKNYVRAYGLGVKMMSGAITILFFAWTINGVVSDMQTGKYLSGLVAESIGAEFLPAILFVLAAAMAFSTGTSWGTFGIMLPIGAAMAVHSDPALIIPCLSAVMAGAVCGDHCSPVSDTTILSSTGAQCNHMDHVISQLPYALLVATASIVGYLVVGFTQSAVLGFIATAIVMAILILLFKEKKH
>LR134495.1|VEI77136.1|1229553_1230306_+|NADP-dependent-3-hydroxy-acid-dehydrogenase-YdfG
MKIALVTGATAGFGLAICKLLLQSGYKVIGTGRRAERLEELHLQFGDKFLPLAFDIQQPDEVEKALNSRPKAWQQIDLLVNNAGLALGLEPAQKADLNDWYQMIDTNIKGLVTMTRLVLPEMVERNSGHIINIGSIAGTYPYPGGNVYGGTKAFVKQFSLNLRADLAGTKVRVSNVEPGLCGGTEFSNVRFKGNDEKAAKVYENVQFVRPEDVANIVLWLNQQPEHVNINRVEVMPVAQTSSALNVARNL
>LR134495.1|VEI77137.1|1230639_1231830_+|Tryptophan-synthase-beta-chain
MSDTLLNPYFGEFGGMYVPEILVPVLKELEQAFVEAQQDPAFQAEFADLLKNYAGRPTALTLCRNLTKGSKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALACAMLGMPCVVYMGAKDVERQSPNVFRMRLMGAEVIPVQKGSCSLKDACCEAMRDWAANYDTTHYLIGTAAGPHPFPTMVREFQKMIGEETKRQILAKEDRLPDAVIAAVGGGSNAIGMFADFIEEQSVTLIGVEPAGKGIETGEHGAPLKHGTTGIYFGMKSPIMQDKDGQIEESYSISAGLDFPSVGPQHAYLNATGRAEYVSITDAEALEAFQALAKNEGIIPALESSHALAYALKMIQQNPEKEQLLVVNLSGRGDKDIFTVDKILNGGE
>LR134495.1|VEI77139.1|1231831_1232638_+|Tryptophan-synthase-alpha-chain
MSRFDTLFTALKAKNEGAFVPFVTLCDPDFERSFEIIDTMIKNGADALELGFPFSDPLLDGPVIQAANKRALDGGYSTDSCFELITKIRAKYPDIPIGLLLCANLIFVPTAEVFFQRCQQSGVDAVLIADLPVFAAQEFVPTAEKYSIQPVFICPPNAVQNTIERIAQLTQGYTYLVSRAGVTSAENQAHASNLDNLVESLKQAGAAPILQGFGIAKPEQVKEALRLGADGAISGSAIVKIIERNLADQANLLKELAEFVQAMKAATK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134495_1	1.7\|1219991\|35\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219991-1220025	35	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	257247-257281	7	0.8
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	AJ748296	Sulfolobus islandicus rudivirus 1 variant XX, complete genome	10195-10227	8	0.758
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	AJ414696	Sulfolobus virus SIRV-1 complete viral genome	10495-10527	8	0.758
LR134495_1	1.15\|1220529\|34\|LR134495\|CRISPRCasFinder	1220529-1220562	34	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	11514-11547	8	0.765
LR134495_1	1.15\|1220529\|34\|LR134495\|CRISPRCasFinder	1220529-1220562	34	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	47660-47693	8	0.765
LR134495_1	1.3\|1219726\|34\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219726-1219759	34	MH617467	Inoviridae sp. isolate ctba17, complete genome	2180-2213	9	0.735
LR134495_1	1.8\|1220058\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1220058-1220090	33	LC494302	Escherichia phage SP27 DNA, complete genome	336020-336052	9	0.727
LR134495_1	1.8\|1220058\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1220058-1220090	33	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	140516-140548	9	0.727
LR134495_1	1.15\|1220529\|34\|LR134495\|CRISPRCasFinder	1220529-1220562	34	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	210650-210683	9	0.735
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP047086	Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence	77258-77290	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NC_005707	Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence	28308-28340	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP053930	Bacillus cereus strain FDAARGOS_797 plasmid unnamed1, complete sequence	165122-165154	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP022346	Bacillus thuringiensis strain c25 plasmid unnamed1, complete sequence	291661-291693	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP040343	Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence	157029-157061	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP040341	Bacillus cereus strain DLOU-Tangshan plasmid unnamed1, complete sequence	181001-181033	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NC_018492	Bacillus cereus FRI-35 plasmid p01, complete sequence	98019-98051	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP033789	Bacillus sp. FDAARGOS_527 plasmid unnamed2, complete sequence	97215-97247	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	115933-115965	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP053290	Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence	256042-256074	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	20919-20951	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	91556-91588	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP045534	Bacillaceae bacterium C02 plasmid unnamed1, complete sequence	76536-76568	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	147965-147997	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NC_011777	Bacillus cereus AH820 plasmid pAH820_272, complete sequence	105557-105589	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	137280-137312	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP042928	Bacillus cereus strain G1-1 plasmid unnamed, complete sequence	122246-122278	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	5316-5348	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	146834-146866	10	0.697
LR134495_1	1.4\|1219792\|33\|LR134495\|PILER-CR,CRISPRCasFinder,CRT	1219792-1219824	33	NZ_CP009299	Bacillus cereus D17 plasmid unnamed, complete sequence	12275-12307	10	0.697
LR134495_1	1.15\|1220529\|34\|LR134495\|CRISPRCasFinder	1220529-1220562	34	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	82917-82950	10	0.706

1. spacer 1.7|1219991|35|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 7, identity: 0.8

atttccatgatttaaggcatacttgggccagttgg	CRISPR spacer
atttccacgatttaaggcatacttgtgcaactgct	Protospacer
*******.***************** ** * *

2. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to AJ748296 (Sulfolobus islandicus rudivirus 1 variant XX, complete genome) position: , mismatch: 8, identity: 0.758

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
ggaaatgaaatagttaggataaaagaaaatatg	Protospacer
   * ********** *****.*********.

3. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to AJ414696 (Sulfolobus virus SIRV-1 complete viral genome) position: , mismatch: 8, identity: 0.758

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
ggtaacgaaatagttaggataaaagaaaatatg	Protospacer
  ** .********* *****.*********.

4. spacer 1.15|1220529|34|LR134495|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 8, identity: 0.765

ttacaagatgctgaagtagttaaa---tcaatagcac	CRISPR spacer
ttacaagatgatgaagaagttaaagattggttag---	Protospacer
********** ***** *******   * . ***

5. spacer 1.15|1220529|34|LR134495|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 8, identity: 0.765

ttacaagatgctgaagtagttaaa---tcaatagcac	CRISPR spacer
ttacaagatgatgaagaagttaaagattggttag---	Protospacer
********** ***** *******   * . ***

6. spacer 1.3|1219726|34|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to MH617467 (Inoviridae sp. isolate ctba17, complete genome) position: , mismatch: 9, identity: 0.735

tatctatattggtaataaaggtactaatatgtgg-	CRISPR spacer
aacctattttggtaataaaggttctaa-acataaa	Protospacer
 *.**** ************** **** *..*..

7. spacer 1.8|1220058|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 9, identity: 0.727

gaccatattcaaacgcattgccgtagtattgat	CRISPR spacer
ttggaaattcaaacgcattgccatagttttctt	Protospacer
    * ****************.**** **  *

8. spacer 1.8|1220058|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 9, identity: 0.727

gaccatattcaaacgcattgccgtagtattgat	CRISPR spacer
ttggaaattcaaacgcattgccatagttttctt	Protospacer
    * ****************.**** **  *

9. spacer 1.15|1220529|34|LR134495|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 9, identity: 0.735

ttacaagatgctgaagtagttaaa-----tcaatagcac	CRISPR spacer
ttacaagatgcttatgtagttaaaggacgttatt-----	Protospacer
************ * *********     *.* *

10. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047086 (Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

11. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_005707 (Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

12. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053930 (Bacillus cereus strain FDAARGOS_797 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

13. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022346 (Bacillus thuringiensis strain c25 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

14. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040343 (Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

15. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040341 (Bacillus cereus strain DLOU-Tangshan plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

16. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_018492 (Bacillus cereus FRI-35 plasmid p01, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

17. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033789 (Bacillus sp. FDAARGOS_527 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

18. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

19. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053290 (Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

20. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

21. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

22. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045534 (Bacillaceae bacterium C02 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

23. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

24. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_011777 (Bacillus cereus AH820 plasmid pAH820_272, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

25. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

26. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042928 (Bacillus cereus strain G1-1 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

27. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

28. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

29. spacer 1.4|1219792|33|LR134495|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009299 (Bacillus cereus D17 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

cctactgaaatagtttggatagaagaaaatact	CRISPR spacer
aagtatgaaattgtttggaaagaagaaaaaaga	Protospacer
     ****** ******* ********* *

30. spacer 1.15|1220529|34|LR134495|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 10, identity: 0.706

ttacaagatgctgaagtagttaaatcaatagcac	CRISPR spacer
ttacaagatgcttatgtagttaaaggaagctatt	Protospacer
************ * *********  **     .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

223796 : 265783

Mannheimia_phage(76.47%)

tail,head

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEI74674.1\|223796_225695_+	Heat shock protein 70	A0A0N9QXN8	Chrysochromulina_ericina_virus	3.6e-150	50.4
VEI74677.1\|225847_226273_+	CRISPR associated protein Cas2	NA	NA	NA	NA
VEI74680.1\|226304_226607_+	Uncharacterised protein	NA	NA	NA	NA
VEI74683.1\|226661_227774_+	Heat shock protein J	A0A0P0YNN4	Yellowstone_lake_phycodnavirus	4.0e-24	33.4
VEI74686.1\|227956_228655_-	Uncharacterized HTH-type transcriptional regulator HI_1476	F6MII3	Haemophilus_phage	8.0e-63	57.9
VEI74689.1\|228885_229155_+	DNA-binding transcriptional regulator Nlp	F6MII4	Haemophilus_phage	6.7e-18	58.0
VEI74691.1\|229188_231132_+	Integrase core domain	A0A0M3LPN5	Mannheimia_phage	0.0e+00	90.7
VEI74693.1\|231136_231361_+	Uncharacterised protein	NA	NA	NA	NA
VEI74696.1\|231357_232239_+	putative secretion ATPase, PEP-CTERM locus subfamily	A0A0M3LP72	Mannheimia_phage	2.5e-154	98.6
VEI74699.1\|232249_232570_+	Uncharacterised protein	A0A0M3LQH1	Mannheimia_phage	4.0e-46	100.0
VEI74702.1\|232572_232764_+	Uncharacterised protein	A0A0M3LQK4	Mannheimia_phage	3.3e-27	98.4
VEI74705.1\|232776_233394_+	Protein of uncharacterised function (DUF3164)	A0A0M3LQ92	Mannheimia_phage	1.8e-106	93.7
VEI74708.1\|233395_233602_+	Uncharacterised protein	A0A0M3LRQ9	Mannheimia_phage	5.3e-31	97.1
VEI74711.1\|233712_233916_+	Uncharacterised protein	A0A0M3LSH0	Mannheimia_phage	1.2e-14	85.4
VEI74714.1\|233925_234105_+	Uncharacterised protein	NA	NA	NA	NA
VEI74718.1\|234112_234298_+	Uncharacterised protein	A0A0M3LSN0	Mannheimia_phage	2.3e-22	88.3
VEI74721.1\|234320_234896_+	Uncharacterised protein	A0A0M3LP85	Mannheimia_phage	7.9e-101	94.8
VEI74724.1\|234899_235295_+	Uncharacterised protein	NA	NA	NA	NA
VEI74727.1\|235451_235712_+	Uncharacterised protein	A0A0M3LPZ3	Mannheimia_phage	1.3e-07	52.0
VEI74730.1\|235708_236263_+	Uncharacterised protein	A0A0M3LPP6	Mannheimia_phage	3.7e-95	97.8
VEI74733.1\|236246_236672_+	Mu-like prophage protein gp16	A0A0M3LP80	Mannheimia_phage	1.8e-70	94.3
VEI74736.1\|236753_236957_+	Uncharacterised protein	NA	NA	NA	NA
VEI74739.1\|236953_237304_+	Uncharacterised protein	A0A0M3LQH8	Mannheimia_phage	7.3e-49	88.8
VEI74742.1\|237438_237861_+	Uncharacterized conserved protein	A0A0M3LRS6	Mannheimia_phage	1.9e-72	95.7
VEI74745.1\|237946_238480_+	Predicted lysozyme (DUF847)	A0A0M3LSH2	Mannheimia_phage	4.5e-82	81.4
VEI74748.1\|238482_238716_+	Protein of uncharacterised function (DUF2644)	A0A0M3LSN9	Mannheimia_phage	9.8e-34	93.2
VEI74751.1\|238712_239084_+	Protein of uncharacterised function (DUF2681)	A0A0M3LP93	Mannheimia_phage	7.1e-10	38.7
VEI74754.1\|239080_239254_+	Uncharacterised protein	A0A0M3LQ02	Mannheimia_phage	2.1e-17	88.0
VEI74757.1\|239246_239504_+	Uncharacterised protein	A0A0M3LPQ4	Mannheimia_phage	9.5e-14	100.0
VEI74760.1\|239503_239758_+	Uncharacterised protein	A0A0M3LP87	Mannheimia_phage	6.3e-26	88.1
VEI74762.1\|239765_240266_+	Protein of uncharacterised function (DUF1804)	A0A0M3LQI8	Mannheimia_phage	7.9e-81	96.4
VEI74765.1\|240265_240412_+	Uncharacterised protein	A0A0M3LQM0	Mannheimia_phage	3.6e-18	87.5
VEI74768.1\|240415_242041_+	phage uncharacterized protein, C-terminal domain	A0A0M3LQB7	Mannheimia_phage	1.1e-301	93.0
VEI74771.1\|242100_243774_+	Mu-like prophage protein gp29	A0A0M3LRU4	Mannheimia_phage	4.9e-292	90.8
VEI74774.1\|243760_245065_+\|head	phage head morphogenesis protein, SPP1 gp7 family	A0A0M3LSH7	Mannheimia_phage	3.4e-240	94.9
VEI74777.1\|245215_245632_+	Mu-like prophage protein gpG	A0A0M3LSP9	Mannheimia_phage	1.2e-71	97.1
VEI74780.1\|245888_246965_+	Mu-like prophage I protein	A0A0M3LPA7	Mannheimia_phage	8.9e-154	81.2
VEI74783.1\|246964_247873_+\|head	Mu-like prophage major head subunit gpT	A0A0M3LQ11	Mannheimia_phage	3.0e-54	38.0
VEI74786.1\|247907_248336_+	Uncharacterised protein	A0A0M3LPR6	Mannheimia_phage	8.7e-28	86.8
VEI74789.1\|248335_248761_+	Mu-like prophage protein gp36	A0A0M3LP98	Mannheimia_phage	1.2e-72	99.3
VEI74792.1\|248757_249396_+	Mu-like prophage protein gp37	A0A0M3LQJ7	Mannheimia_phage	2.7e-110	99.0
VEI74795.1\|249392_249659_+	Uncharacterised protein	B7SDP6	Haemophilus_phage	1.7e-26	65.9
VEI74798.1\|249645_249825_+	Uncharacterised protein	A0A0M3LQM9	Mannheimia_phage	2.2e-25	100.0
VEI74801.1\|249824_251237_+\|tail	Mu-like prophage tail sheath protein gpL	A0A0M3LQC3	Mannheimia_phage	7.9e-251	98.3
VEI74804.1\|251247_251622_+	Uncharacterised protein	A0A0M3LRV6	Mannheimia_phage	3.0e-48	75.0
VEI74807.1\|251621_251987_+	Uncharacterised protein	A0A0M3LSI2	Mannheimia_phage	5.8e-49	82.8
VEI74810.1\|252257_254645_+\|tail	phage tail tape measure protein, TP901 family, core region	A0A0M3LPB6	Mannheimia_phage	3.5e-291	76.4
VEI74813.1\|254644_256003_+	Mu-like prophage DNA circulation protein	F6MIL2	Haemophilus_phage	1.4e-151	59.5
VEI74817.1\|256006_257179_+\|tail	Mu-like prophage tail protein gpP	A0A0M3LPS4	Mannheimia_phage	4.1e-197	91.8
VEI74820.1\|257181_257835_+	Mu-like prophage protein gp45	A0A0M3LPA3	Mannheimia_phage	1.3e-96	86.6
VEI74828.1\|257940_258291_+	Phage protein GP46	A0A0M3LQK5	Mannheimia_phage	6.4e-53	88.8
VEI74835.1\|258293_259355_+	Uncharacterized homolog of phage Mu protein gp47	F6MIL6	Haemophilus_phage	1.8e-151	77.9
VEI74838.1\|259354_259939_+	Uncharacterized protein conserved in bacteria (DUF2313)	F6MIL7	Haemophilus_phage	1.6e-88	83.0
VEI74841.1\|259954_261586_+\|tail	Phage tail fibre repeat	F6MIL8	Haemophilus_phage	2.5e-22	68.4
VEI74844.1\|261587_262196_+	Uncharacterised protein	NA	NA	NA	NA
VEI74847.1\|262188_262653_+	Uncharacterised protein	F6MIM0	Haemophilus_phage	7.4e-57	64.1
VEI74850.1\|262953_263796_+	Site-specific DNA methylase	F6MIM2	Haemophilus_phage	1.6e-110	68.7
VEI74855.1\|264274_265783_+	Catalase	A0A2K9L0T1	Tupanvirus	8.8e-99	47.6

DBSCAN-SWA_2

1646045 : 1652843

Organic_Lake_phycodnavirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEI77729.1\|1646045_1647098_-	Rod shape-determining protein MreB	F2Y2E1	Organic_Lake_phycodnavirus	1.2e-06	22.1
VEI77730.1\|1647212_1647842_-	Arginine exporter protein ArgO	NA	NA	NA	NA
VEI77731.1\|1647945_1648593_+	Uridine kinase	A0A1V0SAA3	Catovirus	4.7e-33	36.6
VEI77732.1\|1648602_1649184_+	Deoxycytidine triphosphate deaminase	I4AZP2	Saccharomonospora_phage	5.9e-27	38.4
VEI77733.1\|1649261_1649417_+	Small integral membrane protein	NA	NA	NA	NA
VEI77734.1\|1649545_1650148_-	SNARE associated Golgi protein	NA	NA	NA	NA
VEI77735.1\|1650149_1651169_-	Purine nucleotide synthesis repressor	C6ZCU4	Enterobacteria_phage	3.9e-34	33.2
VEI77736.1\|1651304_1652033_-\|tRNA	tRNA (cmo5U34)-methyltransferase	H9YRL8	environmental_Halophage	1.6e-21	28.7
VEI77737.1\|1652042_1652843_-	Esterase ybfF	G1DB77	Mycobacterium_phage	1.0e-05	37.4

DBSCAN-SWA_3

1729947 : 1739991

Chrysochromulina_ericina_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEI77809.1\|1729947_1731801_-	Hsc66	A0A0N9QXN8	Chrysochromulina_ericina_virus	3.8e-112	43.8
VEI77810.1\|1731850_1732483_-	Protein of uncharacterised function DUF2625	NA	NA	NA	NA
VEI77811.1\|1732536_1733058_-	Hsc20	NA	NA	NA	NA
VEI77812.1\|1733067_1733391_-	Iron-sulfur cluster assembly protein	A0A2H4N7N5	Lake_Baikal_phage	9.8e-24	46.7
VEI77813.1\|1733499_1733883_-	NifU-like protein	A0A218MKD1	uncultured_virus	5.0e-51	74.2
VEI77814.1\|1734003_1735224_-	Cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.0e-28	29.7
VEI77815.1\|1735277_1735730_-	HTH-type transcriptional regulator iscR	NA	NA	NA	NA
VEI77816.1\|1736095_1737424_+	47 kDa outer membrane protein precursor	NA	NA	NA	NA
VEI77817.1\|1737490_1738045_+	Methylated-DNA--protein-cysteine methyltransferase, constitutive	M1PFU9	Streptococcus_phage	2.1e-29	45.9
VEI77818.1\|1738140_1739991_-	Aerobic respiration control sensor protein ArcB	A0A1V0SGX0	Hokovirus	7.3e-39	30.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage