CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134496	Campylobacter jejuni strain NCTC13266 genome assembly, chromosome: 1	1 crisprs	DEDDh,WYL,c2c9_V-U4,cas2,cas1,cas9,csa3	0	3	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134496_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134496_2

1485408-1485574

TypeII

Consensus_repeat	Method
GTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATAG	PILER-CR

2 spacers

cas2,cas1,cas9

The CRISPR arrays of LR134496_2

>merge|LR134496|2|1485408-1485574|PILER-CR
TTAGTCCCTTTTTAAATTTCTTTATGGTAAAATATTATTACTTACTTAAGGATTAAAAATGACGTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATAGGCGGTTTAATTAAACTTAAAAATGAAAAGTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATAG

>LR134496|2|1|1485408-1485574|PILER-CR
TTAGTCCCTTTTTAAATTTCTTTATGGTAAAATATTAT	TACTTACTTAAGGATTAAAAATGACGTT
TTAGTCCCTTTTTAAATTTCTTTATGGTAAAATAGGCG	GTTTAATTAAACTTAAAAATGAAAAGTT
TTAGTCCCTTTTTAAATTTCTTTATGGTAAAATAG

Protein	Signature genes	Signature genes Name	Protein_function
LR134496.1\|VEI79843.1\|1483428_1483650_+\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|224888
LR134496.1\|VEI79855.1\|1495869_1496319_-\|bacterioferritin	unknown	unknown	gnl\|CDD\|223854
LR134496.1\|VEI79849.1\|1490188_1491643_+\|C4-dicarboxylate-anaerobic-carrier,-putative	unknown	unknown	gnl\|CDD\|225611
LR134496.1\|VEI79838.1\|1478888_1479431_-\|Formate-dehydrogenase-O,-major-subunit-@-selenocysteine-containing	unknown	unknown	gnl\|CDD\|239153
LR134496.1\|VEI79846.1\|1485717_1486149_-\|CRISPR-associated-Cas2-family-protein	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
LR134496.1\|VEI79852.1\|1493315_1494065_+\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768
LR134496.1\|VEI79848.1\|1487018_1489982_-\|CRISPR-associated-protein	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
LR134496.1\|VEI79850.1\|1491663_1492653_-\|Phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
LR134496.1\|VEI79836.1\|1475988_1476630_-\|Formate-dehydrogenase-O,-iron-sulfur-subunit;-Putative-formate-dehydrogenase-iron-sulfur-subunit	unknown	unknown	gnl\|CDD\|319893
LR134496.1\|VEI79847.1\|1486141_1487032_-\|CRISPR-associated-protein	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
LR134496.1\|VEI79842.1\|1481885_1483427_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|225043
LR134496.1\|VEI79840.1\|1479596_1480298_-\|Putative-formate-dehydrogenase-specific-chaperone	unknown	unknown	gnl\|CDD\|225916
LR134496.1\|VEI79839.1\|1479430_1479622_-\|tat-domain-protein	unknown	unknown	gnl\|CDD\|236534
LR134496.1\|VEI79854.1\|1494767_1495805_-\|helix-turn-helix-containing-protein	unknown	unknown	gnl\|CDD\|224292
LR134496.1\|VEI79851.1\|1492713_1493319_+\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
LR134496.1\|VEI79845.1\|1484100_1485291_+\|Molybdopterin-biosynthesis-protein-MoeA	unknown	unknown	gnl\|CDD\|223380
LR134496.1\|VEI79844.1\|1483650_1484097_+\|molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
LR134496.1\|VEI79841.1\|1480613_1481762_-\|carboxynorspermidine-decarboxylase	unknown	unknown	gnl\|CDD\|273414
LR134496.1\|VEI79853.1\|1494039_1494771_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225539
LR134496.1\|VEI79837.1\|1476626_1478867_-\|formate-dehydrogenase,-alpha-subunit	unknown	unknown	gnl\|CDD\|239153

Protein	Function_ID	Function_description	E-value
LR134496.1\|VEI79843.1\|1483428_1483650_+\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|224888	COG1977, MoaD, Molybdopterin converting factor, small subunit [Coenzyme metabolism].	1.67964e-11
LR134496.1\|VEI79855.1\|1495869_1496319_-\|bacterioferritin	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.92874e-51
LR134496.1\|VEI79849.1\|1490188_1491643_+\|C4-dicarboxylate-anaerobic-carrier,-putative	gnl\|CDD\|225611	COG3069, DcuC, C4-dicarboxylate transporter [Energy production and conversion].	6.55616e-71
LR134496.1\|VEI79838.1\|1478888_1479431_-\|Formate-dehydrogenase-O,-major-subunit-@-selenocysteine-containing	gnl\|CDD\|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	2.71388e-62
LR134496.1\|VEI79846.1\|1485717_1486149_-\|CRISPR-associated-Cas2-family-protein	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.59333e-58
LR134496.1\|VEI79852.1\|1493315_1494065_+\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	4.16989e-92
LR134496.1\|VEI79848.1\|1487018_1489982_-\|CRISPR-associated-protein	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
LR134496.1\|VEI79850.1\|1491663_1492653_-\|Phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
LR134496.1\|VEI79836.1\|1475988_1476630_-\|Formate-dehydrogenase-O,-iron-sulfur-subunit;-Putative-formate-dehydrogenase-iron-sulfur-subunit	gnl\|CDD\|319893	cd16371, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	7.03516e-57
LR134496.1\|VEI79847.1\|1486141_1487032_-\|CRISPR-associated-protein	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	8.47058e-121
LR134496.1\|VEI79842.1\|1481885_1483427_+\|oxidoreductase	gnl\|CDD\|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	9.25542e-121
LR134496.1\|VEI79840.1\|1479596_1480298_-\|Putative-formate-dehydrogenase-specific-chaperone	gnl\|CDD\|225916	COG3381, TorD, Uncharacterized component of anaerobic dehydrogenases [General function prediction only].	0.000549526
LR134496.1\|VEI79839.1\|1479430_1479622_-\|tat-domain-protein	gnl\|CDD\|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	0.00441722
LR134496.1\|VEI79854.1\|1494767_1495805_-\|helix-turn-helix-containing-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.6328e-34
LR134496.1\|VEI79851.1\|1492713_1493319_+\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	6.10073e-70
LR134496.1\|VEI79845.1\|1484100_1485291_+\|Molybdopterin-biosynthesis-protein-MoeA	gnl\|CDD\|223380	COG0303, MoeA, Molybdopterin biosynthesis enzyme [Coenzyme metabolism].	4.87129e-141
LR134496.1\|VEI79844.1\|1483650_1484097_+\|molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	1.29857e-42
LR134496.1\|VEI79841.1\|1480613_1481762_-\|carboxynorspermidine-decarboxylase	gnl\|CDD\|273414	TIGR01047, carboxynorspermidine_decarboxylase, carboxynorspermidine decarboxylase. This protein is related to diaminopimelate decarboxylase. It is the last enzyme in norspermidine biosynthesis by an unusual pathway shown in Vibrio alginolyticus. [Central intermediary metabolism, Polyamine biosynthesis].	0
LR134496.1\|VEI79853.1\|1494039_1494771_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase-domain-containing-protein	gnl\|CDD\|225539	COG2992, Bax, Uncharacterized FlgJ-related protein [General function prediction only].	1.57422e-98
LR134496.1\|VEI79837.1\|1476626_1478867_-\|formate-dehydrogenase,-alpha-subunit	gnl\|CDD\|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	3.66349e-161

>LR134496.1|VEI79845.1|1484100_1485291_+|Molybdopterin-biosynthesis-protein-MoeA
MLMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKALKNQPEFPTSAMDGYAIKFEDQDKPLKILGLTPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENVRVENDTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTKLNYSEIALLAELGFFHIGVFIKPIVGVLSSGSEIKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILITTGGVSMGDFDFLKKAVKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYAREILNSWLLQPKDYICKAFLQGSYKKKTPYLEFVACNVEFKNGRILANLEGKKEGSSAIINNLNNKAALMVVPKECEMLENESLVDIIFMP
>LR134496.1|VEI79844.1|1483650_1484097_+|molybdopterin-synthase-catalytic-subunit
MEHFTLYQGSLDIPKIYSQWYEFAKDKNCGALLTFCGIVREEGGIEALSFDIYEPLLKKWFDEWQKRVDFDGISLLFAHSIGDVAVHESSYFAGILSKQRKLGLKLLNEFVEDFKASAPIWKYDVINKERIYAKERSTKLCGAGLLKG
>LR134496.1|VEI79843.1|1483428_1483650_+|molybdopterin-synthase-sulfur-carrier-subunit
MVKVEFLGPINKENLELEVKNLKELKEILQKDESLKEWLELCAVSLNDEIIFDENTKLKDGDKIALLPPVCGG
>LR134496.1|VEI79842.1|1481885_1483427_+|oxidoreductase
MNRRNFLKFNALTLASMGVAYANPMHDMHSMHKNHSINHDLDTSFINFAPKNLKLLDPKQFPQGEILKALPLLKNESKEKNIFRATLEIKENHIELIKGKKTLFYTYNGLVPAPKIEVFEGDKLEILVKNKLKEATTIHWHGVPVPPDQDGSPHDPILAGEERIYRFEIPQDSAGTYWYHPHPHYTASKQVFMGLAGAFVIKAKKDALSHLKEKDLMISDLRLDENAQIPNNNLNDWLNGREGEFVLINGQFKPQIKLATNERIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKTIYKEELFLSPASRVEVLIDAPKDGNFKLESAYYDRDKMMVKEEPNTLFLANINLKKENIELPKNLKIFKPSEEPKEFKEIIMSEDHMQMHGMMGKSESELKIALASMFLINGKSYDLKRIDLSSKLGVVEDWIVINKSHMDHPFHIHGTQFELISSKLNGKVQKAEFRALRDTINVRPNEELRLRMKQDFKGLRMYHCHILEHEDLGMMGNLEVKE
>LR134496.1|VEI79841.1|1480613_1481762_-|carboxynorspermidine-decarboxylase
MFYEKIQTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLWEAKFAKEYMDKEIHTYSPAFKEDEIGEIASLSHHIVFNSLAQFHKFQAKTQKNSLGLRCNVEFSLAPKELYNPCGRYSRLGIRAKDFENVDLSTIEGLHFHALCEESADALEAVLKAFEEKFGKWIGQMKWVNFGGGHHITKKGYDVEKLIALCKNFSDKYGVQVYLEPGEAVGWQTGNLVASVVDIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNARILATRENEKISDLKENEFSYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGVRLPNLMLLNAKNELQMIREFSYKDYSLRN
>LR134496.1|VEI79840.1|1479596_1480298_-|Putative-formate-dehydrogenase-specific-chaperone
MDLEKLRLARSLYYQCLGELFVFSFSEERLSKLQEYLKTMQECLFDENLKSNFDILLKHLDDENSIQAFFKEYDLLFLSLKNSIPTTFSYIEEGFENSNPLLCVRQILVKSKIRRNEKFFKESEDSVGFCLLLMSEFLRQNEDDLAKELFEKVINKSIDEFLGDVFMNKNANLYKEIASIASAFMEFERLCFEVEKPAKINSKKVQNDLSRSEFLRREANKQRRTREKSQGIS
>LR134496.1|VEI79839.1|1479430_1479622_-|tat-domain-protein
MKNRREFLKKSAFALGAAGVLGSTTLALAKDEERKDLVKGKSKKKEVLFQRSANWENYYIKAE
>LR134496.1|VEI79838.1|1478888_1479431_-|Formate-dehydrogenase-O,-major-subunit-@-selenocysteine-containing
MSSVGENIKLTRRSFLKMAALSSLATPLLARSETLREASADELKEAYEGSKKVKTVCTACSVGCGIIAEVQNGVWVRQEIAQDHPVSSGGHCCKGSDMIDMVRSHVRLKYPMKKENGEWKRISYEQALSEIGEKLAAYRKENPESVMFLGSAKMSNEQAYYVRKFAAFFGTNNVDHQARI
>LR134496.1|VEI79837.1|1476626_1478867_-|formate-dehydrogenase,-alpha-subunit
MANTFGYGAMTNHLGDIQRSKCIIIIGANPAVNHPVGFRHFLKAKEKGAKLIVVDPRFTKSAAKADIYARIRPGTDIAFMYGMLKIIFDEGLEDTKYLDERVFGIDKIREEAAKWTAEEVENVTGISKELLVQITHEVAKNKPTTLIWAMGLTQHTVGTSNTRLAPIVQMVLGNIGKFGGGVNILRGHDNVQGASDMACLSENLPGYYPLNEATWRYYAKIWGVDYEWLLGNFVSKDWMHKTGLSLARWWAAALNGKDGNDAIDNAGTPLKALVVMGNGITSTAQQVKVKEGLEALELLVLADPFVNEAGIIAERKDGIYLLPAATQFETSGSVTATNRSGQWRFKVVDPLYESMEDQEILFELAKKLGFYEDFTKTLRDEKGEIVWPENATREIAKAVRSIGLNGWSPERLKKHTLYWDKFDEVTLEGKDEVAGEYYGLPWPCWSDKHPGSPVLYNTDIEVAKGGMGFRNNFGLEYEGESLLAKNAPLNSPIDTGYPQITKDNIEKVLGITLSAQEKEKMGSTWSYDDSNIIATKCIEKGIVPYGNAKARAVVWTFKDKIPLHREPLHSPRNDLVQKYPSFEDQKALYRVDTKFVSVQQAKDYSKEFPLNLVTARLVNLNGAGMENRASMYLTRLTPEMFCEINPELAKEQDIKAGDMIWVHSPEGTKIHVRVKVNPGVAKDMIFLPFHFTGVMQGVDLTHNFPEGTKPYASGESANTVTNYGYDIMCQIPETKGGLCRISKDGK
>LR134496.1|VEI79836.1|1475988_1476630_-|Formate-dehydrogenase-O,-iron-sulfur-subunit;-Putative-formate-dehydrogenase-iron-sulfur-subunit
MNKVNFANLEKERLKFFCDNERCIDCNGCAVACDEAHELPIHIRRRRVITLNEGIQGKEVSTSISCMHCDDAPCSIVCPVDCFYIRADGIVLHDKEICIGCGYCLYACPFGAPQFPKDSVFGNKGIMDKCTMCAGGPEATNSEKERELYGQNRIAEGKVPVCAAMCSTKALLVGESSKIEEIYHNRLMNRNYGIPNPSESLEWKIAYTGKERL
>LR134496.1|VEI79846.1|1485717_1486149_-|CRISPR-associated-Cas2-family-protein
MIEDKFMRVLLMFDVPTKSKKEQKLASKFRNNLIKLGYFMLQFSVYMRICKGLSSVKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQLNKKQEKYHQQNLFEF
>LR134496.1|VEI79847.1|1486141_1487032_-|CRISPR-associated-protein
MSYDEAFKTLLISSNAKLNLELNHLVIKQDENIAKLFLKDINIIVLESLQVSLSSALFNAFAKHKIILLTCDETHSINGIFTPFLGHFQSAKIAKEQMNVSAQKKAILWQKIIKNKILNQAFVLKKHNKIEQSNELINLAKKVSLNDSKNIEAVAAALYFKTLFGVSFSRDELCFENSALNYGYAIIRACIIRAVCISGLLPWLGIKHDNIYNSFALCDDLIEVFRASVDDCVLKLKGESEFLSKDDKRALISNLQSKINFNGQNYPLNRAINHYVANFKNALLYEDELKIVKFDD
>LR134496.1|VEI79848.1|1487018_1489982_-|CRISPR-associated-protein
MARILAFDIGISSIGWAFSENDELKDCGVRIFTKAENPKTGESLALPRRLARSARKRLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRALNELLSKQDFARVILHIAKRRGYDDIKNNGDEEKGKILKAIKQNEEKLVNYQSVGEYLYKEYFQKFKENSKEFINVRNKKESYERCITQSFLKYELKLIFQKQREFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFSDEKRAPKNSPLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKKLLGLSDDYEFKGEKGTYFIEFKKYKEFIKALGEHNLSQDDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNIGFKALKLITPLMLEGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKKYGKVHKINIELAREVGKNHSQRAKIEKEQNENYKAKKDAELECEKLGLKINSKNILKLRLFKEQKEFCAYSGEKIKLSDLQDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNKTPFEAFGNDNVKWQKIEVLAKNLPEKKQKRILDKNYKDKEQKDFKDRNLNDTRYIARLVLNYTKDYLDFLPLSDDENTKLNDTQKGSKVHVEAKSGMLTSALRHTWGFSTKDRNNHLHHAIDAAIIAYANNSIVKDFSDFKKEQESNSAELYAKKISELDYKNKRKFFEPFSGFRQKVLDKIDEIFVSKPERKKPSGALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSLYKDSLILIQTKDMQEPELVYFNAFTSSTVSLIVSKHDNKFETLSKNQKILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKNELR
>LR134496.1|VEI79849.1|1490188_1491643_+|C4-dicarboxylate-anaerobic-carrier,-putative
MPIFMICSTLLAVIVVTYYILKKYNPIFVFFLSGIILLIFAFYITGTPIPKAPSREHASFLNVLLDSYAFITATFKSQLSGVGLIIMSVAGFAAYMKHINASAKLAFLANKPLGKIKNKYLILSGTFVVGMALKIVISSYAGLLLLLLACIYPVLISLKIRPITAVCVLSLIALDYGPKDGNSINMADMVGQSDNVVGLFLNYQIYSVIAYVVVIAILIPFYFAWIDKRDKEKGVLNDEVEIPQIIDPKCPTFYILFPWLPVVFLFTAYFFTIKLDVVTANFVSISLVFLVEFARHRNARKLGEDMMVILKAMAEIFISVVSIIIAAGVFAEGIKALGGVNILANAVSNLGTGNFAWFGILLSIAILSFLVYFATVIMGSGIAAFNAFGKLAPDIATKLDVAPITLVLPIEIASCLGRAASPIAGGIIALAGFAKVAPMDIIKRTTPLLLIAMLVNVLVAFYLAQTNPLPKEQNTTKIELKIQK
>LR134496.1|VEI79850.1|1491663_1492653_-|Phosphoribosylformylglycinamidine-cyclo-ligase
MKISYEDAGVSIDNGNAFVEAIKPLVKETFNDNVVGGIGSFAGAFRMPSGFKKPVILGATDGVGTKLRLAIDAKKYDTIGQDLVAMCVNDLICNFATPLFFLDYYATAKLEVEVAKAVVSGIAKGCKMANCALIGGETAEMPGMYAKDDFDLAGFAVGMAEEDEIDRSKFVKNGDILLALPSSGLHSNGYSLARKVLFESLKLKFDDKIEGKNLIDILLEPTRIYVRDFLTLKPYISALAHITGGGLVENLPRVLPRGMGATIRKHHLKTPEIFYTIGQAVEESEMYRSFNMGVGLVMVVDPSNVSKVLENSDAFIIGEICINEGIVLE
>LR134496.1|VEI79851.1|1492713_1493319_+|dephospho-CoA-kinase
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHKILDENALELEKIFSPFNLKNLLTKEKKIDRKILGEIVFNNKEAKKTLENFTHPKIRAKILEQMQILDKENKAFFVEIPLFFESGAYENLGKVIVIYTPKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTNSYVDFRQECVKVIQEISKGKM
>LR134496.1|VEI79852.1|1493315_1494065_+|diaminopimelate-epimerase
MKFYKYCASGNDFVITNADRKEDRSALAKELCNRYEGIGGDGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFAHHINKINPNMSFLTGAGIIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCDTGVPHLVHFCQNLDEFNTILCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFTYKNEELFFEGKVKYCFEANYNFS
>LR134496.1|VEI79853.1|1494039_1494771_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase-domain-containing-protein
MKPIIIFLSLFLIPLFADDLKNGFGEEYYKLDIDQKRQIFFIKMNEMFDQSFKKIEQERAFIEAFFKDAYKTGFRTSNQTNLEKLITIKNKYRIENLYDFAEYKKRIQKIPKSMGIAQALVESATGTSRFAREANNLFGEWTWGEKGLIPDLRHPDKKHKIKIFDSLQDSVYSYVLNLNRHFAYEKFRDARAKFASEGKEITGLEAIKTLDSYSERKGYYINLITKIIKRYNLEKYDTNSNNT
>LR134496.1|VEI79854.1|1494767_1495805_-|helix-turn-helix-containing-protein
MKVLNFFYENHPKFEVSYERKNQISKPNIIIKGPRFCGKKTLIFNFLSQFKASEILFLDLYDTRFEKQSLERLADFLNENLQIKILCLYNLDFIPNLEKINIPIILSTNIKDLNVNGFEELELDYFDFEEFISVSKKNLPINNLVGLFLQSGRSKFGEKNILLRQSFTLLELEILKYLALNLGQQISISKIFIELKKRLKTSKDSVYQAIKKLENTYVIYTLKHDEKKLQKIYFKDFGLRNNLCISKDFSHLFENLVLSELFKFKEEFFYNKYFNFYSQISKIAYISSPTLDIDLIKLRAKKILPKALELGIFHVIFITLSSEDSFFEQGVKFEVISFDKFSLGF
>LR134496.1|VEI79855.1|1495869_1496319_-|bacterioferritin
MSVTKQLLQMQADAHHLWVKFHNYHWNVKGLQFFSIHEYTEKAYEEMAELFDSCAERVLQLGEKAITCQKVLMENAKSPKVAKDCFTPLEVIELIKQDYEYLLAEFKKLNEAAEKESDTTTAAFAQENIAKYEKSLWMIGATLQGACKM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	MN530981	Campylobacter phage DA10, complete genome	4533-4560	2	0.929
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP048772	Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence	9247-9274	4	0.857
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP048772	Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence	63373-63400	4	0.857
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	NZ_CP021331	Maritalea myrionectae strain HL2708#5 plasmid pHL2708X3, complete sequence	18683-18710	5	0.821
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MN087708	Edwardsiella phage vB_EtaM-IME523, complete genome	61727-61754	5	0.821
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	AP013405	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S42-C63	20890-20917	5	0.821
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	NC_048849	Enterobacter phage vB_EclM_CIP9, complete genome	126765-126792	5	0.821
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	968484-968511	5	0.821
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	MN694165	Marine virus AFVG_250M579, complete genome	21625-21652	5	0.821
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MT446416	UNVERIFIED: Escherichia virus TH47, complete genome	341368-341395	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP046163	Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence	477614-477641	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	406990-407017	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP046066	Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence	661904-661931	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP044979	Bacillus thuringiensis strain BT62 plasmid pBT62A, complete sequence	267586-267613	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP051863	Acinetobacter baumannii strain Ab-C102 plasmid pAb-C102_1, complete sequence	10658-10685	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP045607	Bacillus cereus strain SB1 plasmid p1, complete sequence	263885-263912	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP045356	Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence	1098908-1098935	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	329266-329293	6	0.786
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	MN047793	Xanthomonas phage Xoo-sp13, complete genome	291075-291102	6	0.786
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MH791411	UNVERIFIED: Escherichia phage Ecwhy_1, complete genome	194632-194659	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	10014-10041	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	LC494302	Escherichia phage SP27 DNA, complete genome	251003-251030	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MT708547	Klebsiella phage Muenster, complete genome	132114-132141	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	AB897757	Klebsiella phage K64-1 DNA, complete genome	9993-10020	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	192625-192652	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	KM507819	Escherichia phage 121Q, complete genome	251749-251776	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	225442-225469	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	NC_027364	Escherichia phage PBECO 4, complete genome	33887-33914	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MH383160	Escherichia phage UB, complete genome	94474-94501	7	0.75
LR134496_2	2.1\|1485446\|28\|LR134496\|PILER-CR	1485446-1485473	28	MK327931	Escherichia phage vB_EcoM_G17, complete genome	250736-250763	7	0.75
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NC_020292	Clostridium saccharoperbutylacetonicum N1-4(HMT) plasmid Csp_135p, complete sequence	55673-55700	7	0.75
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP040857	Lactobacillus plantarum strain 202195 plasmid unnamed, complete sequence	12953-12980	7	0.75
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	CP024688	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-4-144K, complete sequence	144088-144115	7	0.75
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP020115	Nodularia spumigena UHCC 0039 plasmid pUHCC0039a, complete sequence	24551-24578	7	0.75
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_CP032824	Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence	50191-50218	8	0.714
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	NZ_MK715471	Arcobacter cryaerophilus strain M830MA plasmid pM830MA, complete sequence	159160-159187	8	0.714
LR134496_2	2.2\|1485512\|28\|LR134496\|PILER-CR	1485512-1485539	28	MK554696	Fusobacterium phage Fnu1, complete genome	37744-37771	8	0.714
LR134496_1	1.1\|1369638\|34\|LR134496\|CRISPRCasFinder	1369638-1369671	34	MH752385	Bacillus phage Ray17, complete genome	8509-8542	10	0.706

1. spacer 2.2|1485512|28|LR134496|PILER-CR matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 2, identity: 0.929

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
gtggtttaattaaacttaaaaatgaaag	Protospacer
*.*************************.

2. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP048772 (Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence) position: , mismatch: 4, identity: 0.857

gcggttt----aattaaacttaaaaatgaaaa	CRISPR spacer
----tttaagaaattaaacttaaaaatgaaaa	Protospacer
    ***    *********************

3. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP048772 (Campylobacter jejuni strain ZS007 plasmid pCJ145K, complete sequence) position: , mismatch: 4, identity: 0.857

gcggttt----aattaaacttaaaaatgaaaa	CRISPR spacer
----tttaagaaattaaacttaaaaatgaaaa	Protospacer
    ***    *********************

4. spacer 2.1|1485446|28|LR134496|PILER-CR matches to NZ_CP021331 (Maritalea myrionectae strain HL2708#5 plasmid pHL2708X3, complete sequence) position: , mismatch: 5, identity: 0.821

tattacttacttaaggattaaaaatgac	CRISPR spacer
ttctacttactttaggaataaaaatgaa	Protospacer
* .********* **** *********

5. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MN087708 (Edwardsiella phage vB_EtaM-IME523, complete genome) position: , mismatch: 5, identity: 0.821

tattacttacttaaggattaaaaatgac	CRISPR spacer
aactaattaattaaggattaaaaatgaa	Protospacer
 *.** *** *****************

6. spacer 2.1|1485446|28|LR134496|PILER-CR matches to AP013405 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S42-C63) position: , mismatch: 5, identity: 0.821

tattacttacttaaggattaaaaatgac	CRISPR spacer
cattacttacataaggattaaatatcat	Protospacer
.********* *********** ** *.

7. spacer 2.1|1485446|28|LR134496|PILER-CR matches to NC_048849 (Enterobacter phage vB_EclM_CIP9, complete genome) position: , mismatch: 5, identity: 0.821

tattacttacttaaggattaaaaatgac	CRISPR spacer
aactaattaattaaggattaaaaatgaa	Protospacer
 *.** *** *****************

8. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 5, identity: 0.821

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
gagccttaattaatcttaaaaatgaaat	Protospacer
* * .******** *************

9. spacer 2.2|1485512|28|LR134496|PILER-CR matches to MN694165 (Marine virus AFVG_250M579, complete genome) position: , mismatch: 5, identity: 0.821

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
gagatttaattagacttgaaaatgaaat	Protospacer
* *.********.****.*********

10. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MT446416 (UNVERIFIED: Escherichia virus TH47, complete genome) position: , mismatch: 6, identity: 0.786

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcacacgtacttaaggattaaaaatgag	Protospacer
   .** ********************

11. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP046163 (Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
ttgagttaattaaacttaataatgaaat	Protospacer
 .*. ************** *******

12. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
cgaatttaattaaatataaaaatgaaaa	Protospacer
  ..**********. ************

13. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP046066 (Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
ttgagttaattaaacttaataatgaaat	Protospacer
 .*. ************** *******

14. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP044979 (Bacillus thuringiensis strain BT62 plasmid pBT62A, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
cgaatttaattaaatataaaaatgaaaa	Protospacer
  ..**********. ************

15. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP051863 (Acinetobacter baumannii strain Ab-C102 plasmid pAb-C102_1, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
gtcgtttaattaaacttaaagatgatcg	Protospacer
*. *****************.****  .

16. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP045607 (Bacillus cereus strain SB1 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
cgaatttaattaaatataaaaatgaaaa	Protospacer
  ..**********. ************

17. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP045356 (Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
ttgagttaattaaacttaataatgaaat	Protospacer
 .*. ************** *******

18. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
cgaatttaattaaatataaaaatgaaaa	Protospacer
  ..**********. ************

19. spacer 2.2|1485512|28|LR134496|PILER-CR matches to MN047793 (Xanthomonas phage Xoo-sp13, complete genome) position: , mismatch: 6, identity: 0.786

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
gttgtttaattaatcttaaaaataaagt	Protospacer
*. ********** *********.**.

20. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MH791411 (UNVERIFIED: Escherichia phage Ecwhy_1, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcacacgtacttaaggattaaaaatggg	Protospacer
   .** *******************.

21. spacer 2.1|1485446|28|LR134496|PILER-CR matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
acatacatacttgaggattaaaaatgga	Protospacer
   *** *****.*************.

22. spacer 2.1|1485446|28|LR134496|PILER-CR matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

23. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MT708547 (Klebsiella phage Muenster, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
acatacatacttgaggattaaaaatgga	Protospacer
   *** *****.*************.

24. spacer 2.1|1485446|28|LR134496|PILER-CR matches to AB897757 (Klebsiella phage K64-1 DNA, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
acatacatacttgaggattaaaaatgga	Protospacer
   *** *****.*************.

25. spacer 2.1|1485446|28|LR134496|PILER-CR matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

26. spacer 2.1|1485446|28|LR134496|PILER-CR matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

27. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

28. spacer 2.1|1485446|28|LR134496|PILER-CR matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

29. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

30. spacer 2.1|1485446|28|LR134496|PILER-CR matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 7, identity: 0.75

tattacttacttaaggattaaaaatgac	CRISPR spacer
gcatactttcttgaggattaaaaatggt	Protospacer
   ***** ***.*************..

31. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NC_020292 (Clostridium saccharoperbutylacetonicum N1-4(HMT) plasmid Csp_135p, complete sequence) position: , mismatch: 7, identity: 0.75

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
ctaatttaattaaagtgaaaaatgaaat	Protospacer
 ...********** * **********

32. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP040857 (Lactobacillus plantarum strain 202195 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.75

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
attctttaattaaacttaacaattaaag	Protospacer
..  *************** *** ***.

33. spacer 2.2|1485512|28|LR134496|PILER-CR matches to CP024688 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-4-144K, complete sequence) position: , mismatch: 7, identity: 0.75

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
atatgttaattaaaattaaaaatgcaaa	Protospacer
...  ********* ********* ***

34. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP020115 (Nodularia spumigena UHCC 0039 plasmid pUHCC0039a, complete sequence) position: , mismatch: 7, identity: 0.75

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
tttatttaattaaactgaaaaatcaaat	Protospacer
 . .************ ****** ***

35. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_CP032824 (Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence) position: , mismatch: 8, identity: 0.714

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
aaactttaatttaacttaaaaatgattt	Protospacer
. . ******* *************

36. spacer 2.2|1485512|28|LR134496|PILER-CR matches to NZ_MK715471 (Arcobacter cryaerophilus strain M830MA plasmid pM830MA, complete sequence) position: , mismatch: 8, identity: 0.714

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
aaactttaatttaacttaaaaatgattt	Protospacer
. . ******* *************

37. spacer 2.2|1485512|28|LR134496|PILER-CR matches to MK554696 (Fusobacterium phage Fnu1, complete genome) position: , mismatch: 8, identity: 0.714

gcggtttaattaaacttaaaaatgaaaa	CRISPR spacer
aaatacaaattaaatttaaaaatgaaaa	Protospacer
. .  . *******.*************

38. spacer 1.1|1369638|34|LR134496|CRISPRCasFinder matches to MH752385 (Bacillus phage Ray17, complete genome) position: , mismatch: 10, identity: 0.706

ttttttagctttatactcagccttactcatataa	CRISPR spacer
cttacaagctttatactcagccttattgatcgtt	Protospacer
.** . *******************.* **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

648326 : 733247

Campylobacter_phage(42.42%)

plate,tail,transposase,terminase,tRNA,protease,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEI79012.1\|648326_649580_+\|protease	protease	Q6DW11	Phage_TP	7.2e-38	30.8
VEI79013.1\|649580_650075_+	phosphoribosylaminoimidazole carboxylase catalytic subunit	NA	NA	NA	NA
VEI79014.1\|650084_650621_+	Uncharacterised protein	NA	NA	NA	NA
VEI79015.1\|650632_651496_+\|tRNA	Glycyl-tRNA synthetase alpha chain	NA	NA	NA	NA
VEI79016.1\|651482_652208_+	metal-binding protein	NA	NA	NA	NA
VEI79017.1\|652217_652934_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
VEI79018.1\|652930_654088_+	3-deoxy-D-manno-octulosonic-acid transferase	NA	NA	NA	NA
VEI79019.1\|654068_654821_+	pseudouridylate synthase	A0A2H4UV25	Bodo_saltans_virus	3.7e-05	31.8
VEI79020.1\|654888_656226_+	signal recognition particle protein	NA	NA	NA	NA
VEI79021.1\|656290_656518_+	SSU ribosomal protein S16p	NA	NA	NA	NA
VEI79022.1\|656520_656763_+	RNA-binding protein	NA	NA	NA	NA
VEI79023.1\|656755_657295_+	16S rRNA processing protein RimM	NA	NA	NA	NA
VEI79024.1\|657291_657996_+\|tRNA	tRNA (guanine-N(1)-)-methyltransferase	NA	NA	NA	NA
VEI79025.1\|658006_658363_+	LSU ribosomal protein L19p	NA	NA	NA	NA
VEI79026.1\|658495_658909_+	5-hydroxyisourate hydrolase	NA	NA	NA	NA
VEI79027.1\|658932_660273_+	3-deoxy-7-phosphoheptulonate synthase	NA	NA	NA	NA
VEI79028.1\|660269_660599_+	ArsC family protein	NA	NA	NA	NA
VEI79029.1\|661046_664649_+	DNA polymerase III subunit alpha	A0A291AWR1	Streptomyces_phage	4.4e-197	37.3
VEI79030.1\|664661_665294_-	YggS family pyridoxal phosphate enzyme	NA	NA	NA	NA
VEI79031.1\|665329_666076_-	Flagellin C	NA	NA	NA	NA
VEI79032.1\|666117_666588_-	integral membrane protein	NA	NA	NA	NA
VEI79033.1\|666600_667416_-	methyltransferase	NA	NA	NA	NA
VEI79034.1\|667412_668600_-	Peptidase, M48 family protein	NA	NA	NA	NA
VEI79035.1\|668773_669262_-	Uncharacterised protein	NA	NA	NA	NA
VEI79036.1\|669472_670147_-	signal peptidase I	X2KRC9	Campylobacter_phage	9.8e-26	32.1
VEI79037.1\|670296_670497_+	Uncharacterised protein	NA	NA	NA	NA
VEI79038.1\|670493_672569_+	bacteriophage DNA transposition protein A	NA	NA	NA	NA
VEI79039.1\|672739_673663_+	bacteriophage DNA transposition protein B	A0A2H4JAW1	uncultured_Caudovirales_phage	6.7e-09	24.5
VEI79040.1\|673665_673857_+	RNA polymerase sigma70	NA	NA	NA	NA
VEI79041.1\|673853_674039_+	Uncharacterised protein	NA	NA	NA	NA
VEI79042.1\|674171_674513_+	Uncharacterised protein	NA	NA	NA	NA
VEI79043.1\|674619_675105_+	host-nuclease inhibitor protein Gam	A0A2K9VGT9	Faecalibacterium_phage	6.4e-19	33.3
VEI79044.1\|675163_676126_+	Uncharacterised protein	NA	NA	NA	NA
VEI79045.1\|676122_676392_+	Uncharacterised protein	NA	NA	NA	NA
VEI79046.1\|676391_677084_+	Uncharacterised protein	NA	NA	NA	NA
VEI79047.1\|677080_677530_+	Mu-like prophage protein gp16	NA	NA	NA	NA
VEI79048.1\|677576_677852_+	Uncharacterised protein	NA	NA	NA	NA
VEI79049.1\|677843_678515_-	extracellular deoxyribonuclease	NA	NA	NA	NA
VEI79050.1\|678608_678893_+	DNA-binding protein	NA	NA	NA	NA
VEI79051.1\|679038_679401_+	Uncharacterised protein	NA	NA	NA	NA
VEI79052.1\|679421_680399_-\|tail	tail protein D	A0A219Y9Y2	Aeromonas_phage	6.2e-13	25.7
VEI79053.1\|680392_680584_-\|tail	tail protein X	NA	NA	NA	NA
VEI79054.1\|680576_680951_-\|tail	phage tail protein	NA	NA	NA	NA
VEI79055.1\|681076_681976_-	prophage MuSo1, F protein	A0A2P1A4D1	Alteromonadaceae_phage	1.5e-05	37.3
VEI79056.1\|681972_682311_-	prophage MuSo1, F protein	Q6QIB9	Burkholderia_phage	3.3e-14	40.2
VEI79057.1\|682313_682541_-	Uncharacterised protein	NA	NA	NA	NA
VEI79058.1\|682602_683682_-	Mu-like prophage protein gp29	A0A2H4JHL1	uncultured_Caudovirales_phage	2.7e-17	26.6
VEI79059.1\|683691_685362_-\|terminase	phage terminase	A0A0A1IW02	Pseudomonas_phage	5.7e-91	41.1
VEI79060.1\|685333_685630_-\|terminase	phage terminase, small subunit	NA	NA	NA	NA
VEI79061.1\|685702_685960_-\|terminase	phage terminase, small subunit	NA	NA	NA	NA
VEI79062.1\|685952_686411_-	Mu-like prophage protein gp36	NA	NA	NA	NA
VEI79063.1\|686526_687504_-\|capsid	Phage major capsid protein E	R9TRN2	Rhizobium_phage	9.6e-06	23.4
VEI79064.1\|687506_688034_-	Uncharacterised protein	NA	NA	NA	NA
VEI79065.1\|688036_688852_-	Mu-like prophage I protein	A0A2H4JAW3	uncultured_Caudovirales_phage	2.9e-24	48.4
VEI79066.1\|688853_689288_-	Uncharacterised protein	NA	NA	NA	NA
VEI79067.1\|689435_689825_+	peptidase M15 family protein	A0A1X9Q0V8	Human_gokushovirus	5.0e-22	47.1
VEI79068.1\|689835_690177_+	Uncharacterised protein	NA	NA	NA	NA
VEI79069.1\|690173_690422_+	lipoprotein	NA	NA	NA	NA
VEI79070.1\|690408_690531_+	membrane protein	NA	NA	NA	NA
VEI79071.1\|690533_690848_+	Uncharacterised protein	NA	NA	NA	NA
VEI79072.1\|690847_691480_+\|plate	baseplate assembly protein V	V5YUM9	Pseudomonas_phage	1.7e-08	34.6
VEI79073.1\|691676_691967_+\|plate	baseplate assembly protein W	Q8H9N4	Vibrio_phage	2.7e-09	40.8
VEI79074.1\|691963_693130_+\|plate	baseplate assembly protein J	Q8H9N3	Vibrio_phage	1.0e-14	24.9
VEI79075.1\|693126_693747_+\|tail	phage tail protein	A7YH02	Campylobacter_phage	8.7e-61	100.0
VEI79076.1\|693746_694778_+\|tail	tail fiber protein H	A7YH00	Campylobacter_phage	4.3e-190	100.0
VEI79077.1\|694802_695270_+	Uncharacterised protein	A7YGZ9	Campylobacter_phage	1.1e-79	100.0
VEI79078.1\|695266_695638_+	Protein of uncharacterised function (DUF1353)	A7YGH7	Campylobacter_phage	1.5e-68	100.0
VEI79079.1\|695738_696746_+	Uncharacterised protein	A7YGZ7	Campylobacter_phage	1.7e-191	100.0
VEI79080.1\|696764_697958_+\|tail	major tail sheath protein	A7YGZ6	Campylobacter_phage	2.1e-196	99.7
VEI79081.1\|697981_698491_+\|tail	phage major tail tube protein	A7YGZ4	Campylobacter_phage	2.5e-90	100.0
VEI79082.1\|698705_698885_+	Uncharacterised protein	A7YGZ3	Campylobacter_phage	6.0e-23	98.3
VEI79083.1\|698996_699317_-	Uncharacterised protein	NA	NA	NA	NA
VEI79084.1\|699358_701575_+\|tail	TP901 family tail tape measure protein	A7YGZ1	Campylobacter_phage	0.0e+00	99.6
VEI79085.1\|701578_701866_+	phage virion morphogenesis protein	A7YGZ0	Campylobacter_phage	4.6e-41	100.0
VEI79086.1\|702172_703027_+	type II DNA modification methyltransferase	A7YGW6	Campylobacter_phage	1.2e-140	89.9
VEI79087.1\|703464_704016_+	Zn peptidase	Q332A2	Clostridium_botulinum_C_phage	2.1e-10	32.7
VEI79088.1\|704012_704297_-	Uncharacterised protein	A7YG83	Campylobacter_phage	4.2e-47	97.9
VEI79089.1\|704355_704985_-	phage repressor protein	A7YG70	Campylobacter_phage	7.0e-58	93.8
VEI79090.1\|707699_707885_+	molybdenum cofactor biosynthesis protein	NA	NA	NA	NA
VEI79091.1\|707881_708424_-	Molybdopterin biosynthesis Mog protein, molybdochelatase	NA	NA	NA	NA
VEI79092.1\|708444_709428_-	Magnesium and cobalt transport protein CorA	NA	NA	NA	NA
VEI79093.1\|709545_710592_+	Putative periplasmic solute-binding protein	NA	NA	NA	NA
VEI79094.1\|710602_711928_+	putative periplasmic protein	NA	NA	NA	NA
VEI79095.1\|711927_712734_+	type I phosphodiesterase/nucleotide pyrophosphatase	NA	NA	NA	NA
VEI79096.1\|712730_713570_+	ABC transporter permease protein	NA	NA	NA	NA
VEI79097.1\|713570_714350_+	ABC transporter, permease protein	NA	NA	NA	NA
VEI79098.1\|714353_715343_+	Ferric iron ABC transporter, ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-34	40.4
VEI79099.1\|715339_715978_+	putative phosphoserine phosphatase	NA	NA	NA	NA
VEI79100.1\|716001_716757_-	histidine-binding protein precursor	NA	NA	NA	NA
VEI79101.1\|717089_719666_+	Uncharacterised protein	NA	NA	NA	NA
VEI79102.1\|719677_720112_+	hemagglutination domain-containing protein	NA	NA	NA	NA
VEI79103.1\|720071_721700_+	adhesive protein CupB5	NA	NA	NA	NA
VEI79104.1\|721737_723042_+	Filamentous haemagglutinin domain protein	NA	NA	NA	NA
VEI79105.1\|723051_724740_+	Heme/hemopexin transporter protein huxB precursor	NA	NA	NA	NA
VEI79106.1\|732441_732687_+\|transposase	transposase	NA	NA	NA	NA
VEI79107.1\|732896_733247_+\|transposase	transposase	A0A1S5RHD5	Helicobacter_phage	3.1e-31	60.6

DBSCAN-SWA_2

1118695 : 1125632

uncultured_Mediterranean_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEI79485.1\|1118695_1119361_+	N-acylneuraminate cytidylyltransferase	A0A1B1IVD3	uncultured_Mediterranean_phage	1.0e-06	33.3
VEI79486.1\|1119348_1120182_+	acetyltransferase	M1HKK6	Paramecium_bursaria_Chlorella_virus	1.0e-16	38.7
VEI79487.1\|1120173_1120986_-	lipooligosaccharide biosynthesis glycosyltransferase	NA	NA	NA	NA
VEI79488.1\|1121044_1121995_+	heptosyltransferase II	NA	NA	NA	NA
VEI79489.1\|1121980_1122199_-	putative lipooligosaccharide biosynthesis glycosyltransferase	NA	NA	NA	NA
VEI79490.1\|1122207_1122744_-	putative lipooligosaccharide biosynthesis glycosyltransferase	A0A2K9L5B5	Tupanvirus	1.7e-12	39.5
VEI79491.1\|1122743_1123304_-	Phosphoheptose isomerase 1	A0A067XQR2	Caulobacter_phage	2.4e-17	38.1
VEI79492.1\|1123300_1124686_-	D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase	A0A0K0KVL9	Prochlorococcus_phage	5.5e-23	45.4
VEI79493.1\|1124678_1125632_-	ADP-L-glycero-D-manno-heptose-6-epimerase	E3SL51	Synechococcus_phage	4.9e-23	34.8

DBSCAN-SWA_3

1386138 : 1393454

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEI79745.1\|1386138_1386804_-	D-glycero-D-manno-heptose 1-phosphate guanosyltransferase	A0A222YXG2	Synechococcus_phage	1.3e-09	31.8
VEI79746.1\|1386791_1387397_-	Phosphoheptose isomerase	A0A067XQR2	Caulobacter_phage	7.0e-15	33.7
VEI79747.1\|1387417_1387690_-	putative sugar transferase	NA	NA	NA	NA
VEI79748.1\|1387686_1388652_-	sugar transferase	NA	NA	NA	NA
VEI79749.1\|1388639_1389659_-	D-glycero-D-manno-heptose 7-phosphate kinase	A0A222YW25	Synechococcus_phage	6.0e-59	39.9
VEI79750.1\|1389655_1390687_-	GDP-mannose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	2.0e-147	73.6
VEI79751.1\|1390695_1391757_-	GDP-fucose synthetase	M1HKX0	Paramecium_bursaria_Chlorella_virus	2.4e-87	50.1
VEI79752.1\|1391844_1392909_-	GDP-4-keto-6-deoxy-D-sugar-3, 5-epimerase-4-reduct ase	D1LW79	Prochlorococcus_phage	2.4e-79	43.2
VEI79753.1\|1392908_1393454_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D7XFA9	Escherichia_phage	3.7e-15	29.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage