CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134538	Corynebacterium diphtheriae strain NCTC3529 genome assembly, chromosome: 1	1 crisprs	DEDDh,WYL,cas4,csa3,DinG,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	1	4	10	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134538_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134538_2

1766845-1767848

TypeI-E

I-E

Consensus_repeat	Method
GTTTTCCCCGCACCAGCGGGGATGAGCC	CRISPRCasFinder
GTTTTCCCCGCACCAGCGGGGATGAGCC	CRT
GTTTTCCCCGCACCAGCGGGGATGAGCC	PILER-CR

16 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

The CRISPR arrays of LR134538_2

>merge|LR134538|2|1766845-1767848|CRISPRCasFinder,CRT,PILER-CR
GTTTTCCCCGCACCAGCGGGGATGAGCCTGAGGTCTGCTAGGTCATTGTCGGTGTACCCAGGTTTTCCCCGCACCAGCGGGGATGAGCCGCCGCGCATAGGTATCCGTCTCCTCGGCACGATGTTTTCCCCGCACCAGCGGGGATGAGCCTCGTTGACCGTGCTACCGACATGGCTTCGCCCAGTTTTCCCCGCACCAGCGGGGATGAGCCGCATGGAAAGCCGTTATTGCTGACCATAACGAAGTTTTCCCCGCACCAGCGGGGATGAGCCCATCTGGTACGGCAGTGTCTCCTCGGGTAAAACGTTTTCCCCGCACCAGCGGGGATGAGCCCCACCAACAAAACGGGAGACAAACACATGGGAAGTTTTCCCCGCACCAGCGGGGATGAGCCCCACCAACAAAACGGGAGACAAACACATGGGAAGTTTTCCCCGCACCAGCGGGGATGAGCCCTCCTGCCCCGAGGTGACGTTCACATCCAGCTTGTTTTCCCCGCACCAGCGGGGATGAGCCGCCGCGCATAGGTATCCGTCTCGTCGGCACGATGTTTTCCCCGCACCAGCGGGGATGAGCCCTCCTCGAGGCTGATCTCACTGTCCGTGACGGCGTTTTCCCCGCACCAGCGGGGATGAGCCCATGCCACAACACAAAGACCCAAGGCGAGGCAGGTTTTCCCCGCACCAGCGGGGATGAGCCGCTGTGTGGCGTTGCCACGGTGATGTGTAGGTTGTTTTCCCCGCACCAGCGGGGATGAGCCCCTCTCTTTTTATCCTTTTGAGGTCCTCTATCGGTTTTCCCCGCACCAGCGGGGATGAGCCGAAAACCAATACTCCTACAGCTGGAACGACCAAGTTTTCCCCGCACTAGCGGGGATGAGCCGTTGTTAACGGATCCACGAGACACACCCAGTATGTTTTCCCCGCACTAGCGGGGATGAGCCGTCATAATCAGCACTGTCAATCCTCATGTATTGGTTTTCCCCGCACTAGCGGGGATGAGCC

>LR134538|2|2|1766845-1767848|CRISPRCasFinder
GTTTTCCCCGCACCAGCGGGGATGAGCC	TGAGGTCTGCTAGGTCATTGTCGGTGTACCCAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCGCGCATAGGTATCCGTCTCCTCGGCACGAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	TCGTTGACCGTGCTACCGACATGGCTTCGCCCA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCATGGAAAGCCGTTATTGCTGACCATAACGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATCTGGTACGGCAGTGTCTCCTCGGGTAAAAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCAACAAAACGGGAGACAAACACATGGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCAACAAAACGGGAGACAAACACATGGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCCTGCCCCGAGGTGACGTTCACATCCAGCTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCGCGCATAGGTATCCGTCTCGTCGGCACGAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCCTCGAGGCTGATCTCACTGTCCGTGACGGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATGCCACAACACAAAGACCCAAGGCGAGGCAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTGTGTGGCGTTGCCACGGTGATGTGTAGGTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCTCTCTTTTTATCCTTTTGAGGTCCTCTATCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTCATAATCAGCACTGTCAATCCTCATGTATTG
GTTTTCCCCGCACTAGCGGGGATGAGCC

>LR134538|2|1|1766845-1767848|CRT
GTTTTCCCCGCACCAGCGGGGATGAGCC	TGAGGTCTGCTAGGTCATTGTCGGTGTACCCAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCGCGCATAGGTATCCGTCTCCTCGGCACGAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	TCGTTGACCGTGCTACCGACATGGCTTCGCCCA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCATGGAAAGCCGTTATTGCTGACCATAACGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATCTGGTACGGCAGTGTCTCCTCGGGTAAAAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCAACAAAACGGGAGACAAACACATGGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCAACAAAACGGGAGACAAACACATGGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCCTGCCCCGAGGTGACGTTCACATCCAGCTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCGCGCATAGGTATCCGTCTCGTCGGCACGAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCCTCGAGGCTGATCTCACTGTCCGTGACGGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATGCCACAACACAAAGACCCAAGGCGAGGCAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTGTGTGGCGTTGCCACGGTGATGTGTAGGTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCTCTCTTTTTATCCTTTTGAGGTCCTCTATCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTCATAATCAGCACTGTCAATCCTCATGTATTG
GTTTTCCCCGCACTAGCGGGGATGAGCC

>LR134538|2|1|1767028-1767848|PILER-CR
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCATGGAAAGCCGTTATTGCTGACCATAACGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATCTGGTACGGCAGTGTCTCCTCGGGTAAAAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCAACAAAACGGGAGACAAACACATGGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCAACAAAACGGGAGACAAACACATGGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCCTGCCCCGAGGTGACGTTCACATCCAGCTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCGCGCATAGGTATCCGTCTCGTCGGCACGAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCCTCGAGGCTGATCTCACTGTCCGTGACGGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATGCCACAACACAAAGACCCAAGGCGAGGCAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTGTGTGGCGTTGCCACGGTGATGTGTAGGTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCTCTCTTTTTATCCTTTTGAGGTCCTCTATCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTCATAATCAGCACTGTCAATCCTCATGTATTG
GTTTTCCCCGCACTAGCGGGGATGAGCC

Protein	Signature genes	Signature genes Name	Protein_function
LR134538.1\|VEJ66706.1\|1754701_1755346_+\|rhomboid-family-protein	unknown	unknown	gnl\|CDD\|366759
LR134538.1\|VEJ66715.1\|1763806_1766608_+\|CRISPR-associated-protein	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
LR134538.1\|VEJ66711.1\|1760144_1760930_+\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
LR134538.1\|VEJ66719.1\|1769752_1770379_+\|CRISPR-associated-protein	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|378191
LR134538.1\|VEJ66727.1\|1776607_1778113_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
LR134538.1\|VEJ66714.1\|1763032_1763491_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134538.1\|VEJ66718.1\|1768075_1769749_+\|CRISPR-associated-protein	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
LR134538.1\|VEJ66708.1\|1758205_1758874_+\|thiamine-phosphate-pyrophosphorylase	unknown	unknown	gnl\|CDD\|234590
LR134538.1\|VEJ66724.1\|1773848_1774196_+\|CRISPR-associated-protein	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
LR134538.1\|VEJ66712.1\|1760929_1761940_+\|thiamine-biosynthesis-protein-ThiF	unknown	unknown	gnl\|CDD\|235528
LR134538.1\|VEJ66723.1\|1772906_1773842_+\|CRISPR-associated-protein	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
LR134538.1\|VEJ66721.1\|1771531_1772236_+\|CRISPR-associated-protein	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|378243
LR134538.1\|VEJ66709.1\|1758870_1759959_+\|putative-thiamine-biosynthesis-oxidoreductase	unknown	unknown	gnl\|CDD\|274092
LR134538.1\|VEJ66720.1\|1770393_1771527_+\|CRISPR-associated-protein	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
LR134538.1\|VEJ66710.1\|1759942_1760143_+\|thiamine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|273754
LR134538.1\|VEJ66725.1\|1774203_1774473_-\|putative-septation-inhibitor-protein	unknown	unknown	gnl\|CDD\|178907
LR134538.1\|VEJ66707.1\|1756422_1758222_+\|thiamine-biosynthesis-protein-ThiC	unknown	unknown	gnl\|CDD\|236451
LR134538.1\|VEJ66713.1\|1761936_1762752_+\|multifunctional-thiamine-phosphate-pyrophosphorylase	unknown	unknown	gnl\|CDD\|237797
LR134538.1\|VEJ66726.1\|1774589_1776611_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
LR134538.1\|VEJ66722.1\|1772237_1772903_+\|CRISPR-associated-protein	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050

Protein	Function_ID	Function_description	E-value
LR134538.1\|VEJ66706.1\|1754701_1755346_+\|rhomboid-family-protein	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	7.22148e-26
LR134538.1\|VEJ66715.1\|1763806_1766608_+\|CRISPR-associated-protein	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.64913e-92
LR134538.1\|VEJ66711.1\|1760144_1760930_+\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.32018e-147
LR134538.1\|VEJ66719.1\|1769752_1770379_+\|CRISPR-associated-protein	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	4.36173e-32
LR134538.1\|VEJ66727.1\|1776607_1778113_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.77337e-107
LR134538.1\|VEJ66718.1\|1768075_1769749_+\|CRISPR-associated-protein	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.32107e-108
LR134538.1\|VEJ66708.1\|1758205_1758874_+\|thiamine-phosphate-pyrophosphorylase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	4.93107e-63
LR134538.1\|VEJ66724.1\|1773848_1774196_+\|CRISPR-associated-protein	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.19106e-42
LR134538.1\|VEJ66723.1\|1772906_1773842_+\|CRISPR-associated-protein	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	3.88626e-126
LR134538.1\|VEJ66721.1\|1771531_1772236_+\|CRISPR-associated-protein	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	3.80295e-41
LR134538.1\|VEJ66709.1\|1758870_1759959_+\|putative-thiamine-biosynthesis-oxidoreductase	gnl\|CDD\|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	5.08136e-128
LR134538.1\|VEJ66720.1\|1770393_1771527_+\|CRISPR-associated-protein	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.88348e-158
LR134538.1\|VEJ66712.1\|1760929_1761940_+\|thiamine-biosynthesis-protein-ThiF	gnl\|CDD\|235528	PRK05600, PRK05600, thiamine biosynthesis protein ThiF; Validated.	0
LR134538.1\|VEJ66725.1\|1774203_1774473_-\|putative-septation-inhibitor-protein	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	2.52021e-46
LR134538.1\|VEJ66710.1\|1759942_1760143_+\|thiamine-biosynthesis-protein	gnl\|CDD\|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	8.21875e-20
LR134538.1\|VEJ66707.1\|1756422_1758222_+\|thiamine-biosynthesis-protein-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
LR134538.1\|VEJ66713.1\|1761936_1762752_+\|multifunctional-thiamine-phosphate-pyrophosphorylase	gnl\|CDD\|237797	PRK14713, PRK14713, bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.	2.07941e-109
LR134538.1\|VEJ66726.1\|1774589_1776611_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.60189e-122
LR134538.1\|VEJ66722.1\|1772237_1772903_+\|CRISPR-associated-protein	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.80225e-78

>LR134538.1|VEJ66715.1|1763806_1766608_+|CRISPR-associated-protein
MSVVDQADQWRRARSVQAYSLWAKSGSEDLYLRLPQHLIDAACVAEWLWNNWVSDSLKSTLSAAWRLPAEEVGRLYTFYAGTHDVGKATISFQRLVEKTSHGNYLLGPVREAGLSLQWTLNEGEGKKFPHGMASALIIAAWLEKHDIDPSSAARLSFIADAHHGFASDEELYRSHEDTLDYYPPEWLVVHAEILDSMAEITDIGETLEELADQSTPSAPAMQIMTGLVIMADWIASDEKAFPYVCDSSQHDRVVEGMSHVNLPPAWVPTDVPDNVETLFRDTFTWPDSYQVRPVQRAAVAVARAVQDPTLIIIEAPTGEGKTEAGLATSHILGQKTGAQGIFFAAPTMSTANGLFERTKNWAQCTSSRGEVASLYLAHSKNKLSLPFQSLRFTSIGEDDHLEKHGSVVASQWLSGRHRGILSDFVVGTVDQVLMMALQVRFSMLRHVGLAGKIVIIDEVHAYDAYMSQYLYLTLQWLAKYGVSVILMSATLPPQQRARLVNAYASQVCKKADASALNSDAYPLITAVNKKGISVTEVPQENSDTTIKIRRIDDSLPALGGMFSDLLVDGGIALVICNTIRRAQQAYDSLKAIFPDEVELHHAAFIATQRSEKEDALRESLGPHASRGEDRPWRRIVVATQVAEQSLDIDADVLVTDIAPIDLIIQRAGRLHRHERPHSDRPEILGQPQIFIRGINNEEISGELPEFDGGAAAIYGEKILYATVAYLPDEFHRPSDVPKLVKNVYSDTPCIPENWKEQWEQACVKAKENYEKSVRKAQTFSFPQPHMARTLRDLFKQQHSNSVDKKEESGSAQVRDAEFSIEVVALLKTEYGYHPFGREEEIENGRELTWKEAEALAGNTVRLPAQMTRRDSDFNAVIDSLEAQTPPEWQRSGLLKGQVALFFDERGEARLGRFLVRYTNERGLEVEVCPKEDA
>LR134538.1|VEJ66714.1|1763032_1763491_-|Uncharacterised-protein
MAWLGLVGVGWRWWALVGAPPPLTPEKTALHTKSSQTAGLEAIWCEVLCKMPRNTPEWWLGGTGAPFGGKTFGYVRVKPWAGTAAAPARPTRITRTMPSRPPTLALPPFTPEKTALHTKSSQTAGLEAIWCEVRRKILRNTPVWWLSGFRVH
>LR134538.1|VEJ66713.1|1761936_1762752_+|multifunctional-thiamine-phosphate-pyrophosphorylase
MTPHILTIAGSDPSGGAGIQADLKSIMAAGGYGMAAITALTAQNTCGVTAIHTPPTEFLSEQLRAISDDITIHAIKIGMIGSSDAATATATWLDQLPHTPIVVLDPVMVATSGSVLGQRHYFEPLLHHATVITPNLPELAVLTNNHDPEQAEHAARSLAEQYDCAVLLKGGHRHGTDDLGNTWITASGPQFHAPSPRIHTTNTHGTGCSLSSALATRLVIEPPEPALHWATTWLNGAIAHGSDLNVGHGNGPVDHSYRLGEYSANCNTIES
>LR134538.1|VEJ66712.1|1760929_1761940_+|thiamine-biosynthesis-protein-ThiF
MLDELERQRVARQLRLPGFGIEQQERLNKGRVLVIGAGGLGSPALQSLVAAGVGSIRLVDNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPGIRIDAHTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGSITTYNALTSTFRTYTVGRDPLRPAARTLHTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWDDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
>LR134538.1|VEJ66711.1|1760144_1760930_+|thiazole-synthase
MLTIADRSFQSHLIMGTGGASSFDTLEKSLIASGTELTTVAMRRHAAHTGAHGESVFELMQRLNITPLPNTAGCRTARDAILTAQLAREALDTSWIKVEVIADDTTLLPDVLELIDATETLTNDGFTVLAYTSDDPVVAQRLEDAGAAAVMPLGSPIGTGLGILNPHNIELICSRATVPVLLDAGIGTASDATLAMELGCAGVLLASAINRCINPITMATAMKHAVEAGRLAREAGRIPRREHAVASSSFEGLASWADEVL
>LR134538.1|VEJ66710.1|1759942_1760143_+|thiamine-biosynthesis-protein
MDIYINDTLTTIESPQLTEIISNHCNGIRPGIAVAINQRVIPRSQWDTTTVTAGDHLDILTAVQGG
>LR134538.1|VEJ66709.1|1758870_1759959_+|putative-thiamine-biosynthesis-oxidoreductase
MKIAVVGGGIVGLSTAFELSTRGYNVHVFDPNPASGASHFAGGMLAPAAEVQFQQDPLFPLMKRAGKLWPDMVRWVAQHTNLPTGYRTEGTLVVAADRADAEHLKQLRATQEAAGMDVRPITTRQARGLEPALGPRLSAAVHIPNDTQVAPRVFLTALLDALDDCGVEVTKEKITDLEPLYQQFDVVVLAAGLGAQHLSPIPLALRPVRGDILRVQTEPGAVNMVVRGWVNDRPIYIIPRANGEIAIGATSREDERDLPSVEGIYDLLRDAIRVVPGIVDSSLIEANVGVRPGTPDDLPYLGWASDRLIISTGYFRHGILLSSLGAHVTACLIDGTDPGIDLTACAPDRHHNERGTTHGHLH
>LR134538.1|VEJ66708.1|1758205_1758874_+|thiamine-phosphate-pyrophosphorylase
MLPTPRWGRDFDPRCYFVTGTGSVDHIVDVARQAARAGAGLIQVRSKPIAARDLYILGREVARAVTEVNPRTRVLIDDRVDVALALMNNGEHIHGVHVGQDDLPVRHVRALLGDNAIIGLTTGTLELVRASRQVAEVIDYIGAGPFRPTPTKDSGRAPVGLAGYPPLVAESLVPVVAIGDVRPEDAADLAATGVAGVAIVRALMNSQDVATDVKLVLKGFAQ
>LR134538.1|VEJ66707.1|1756422_1758222_+|thiamine-biosynthesis-protein-ThiC
MSAASANSATNPSAWENSEIHPKHSYSPIVSGDLEVPETEIQLDDSPTGPNDPVRIYRTRGPECDPTVGLKPLRAQWIDNREDTEEYAGRERNLADDGRSAQRRGAASLEWKGVKPAPRRAKQGKRVTQMHYARQGIITKEMEFVALREHMDPEFVRSEIARGRAIIPNNINHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLRWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTKRVTGIVSRGGSIMAGWCLAHHKESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSVADANDAAQFAELKTIGELARRAWEYDVQVMIEGPGHVPLNMVQENNELEQKWAHDAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWHDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFADKITDLGIPQVGGDAEAGMAAKSEEFVAQGSQLYSEVRDNAAHA
>LR134538.1|VEJ66706.1|1754701_1755346_+|rhomboid-family-protein
MIAFFNEVGVVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPTHLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLILIAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGGKRG
>LR134538.1|VEJ66718.1|1768075_1769749_+|CRISPR-associated-protein
MASLLEIRWILALDTQGNQISVGIRDIFAGEVQVAYIQGESPAQDYAVMRLLLAIFWRAHSMDIDMDVEPFDFLEWFNKMRRRLARKGKDQVVLDYLDRYADRFELFDAKAPFMQVAGLHVASGEYKHITTIIPEAQDEYFSMRGGKERDSVSIEEAARWLVYVQAFDYSGIKSGAVGDSRVKGGRGYPIGTGWTGMTGGTLVKGEDLLDTLLLNTTLETLNDPEDRPVWERTAYGPDERAVVGENSQPQGPADLATWQSRRIRLMPEGDRVVGVIVCNGDKIPDAGANVLDDPMTPYRFSANKSKKDHDVYYPRPYDVERTMWKALDALVVAETDGGFSAKEKAPKRPKNLASLAELAVQKANVPAVLNVDLVSVEYGPQASSVATTYASRMSMPVVLLLTEAKHLRGKVREIARATTQSAVALGQFSGNLLDAAGGEYAFQPAITDRVLAELEPRFNDWLERLRDISPEQAIQDNESLTDLEKAWQHTARSIIDQHARILLRGAGPKALAGRIQYRDADDHKGRVVSAAGYYRMLQRKLDEVLPLTVRKQEKEGE
>LR134538.1|VEJ66719.1|1769752_1770379_+|CRISPR-associated-protein
MAENKDALRAAVGATCHRLQEAYLGDRNSARHHSARATLAELRRGATVDIRKNPLGLEKVLFAMARDFSDRLVGHGDNPSPSEEAAFVALTLFGVHMQSATSPVHISQVSFASACGRLHSLGTSDSIKPRVDAMLLASQEQARLVHIRSLVTLLRANNIGFDYGLLARDLRALNDPKKRAGIQLRWGRDFAIGHFRNSNSTTNSTQTA
>LR134538.1|VEJ66720.1|1770393_1771527_+|CRISPR-associated-protein
MTLVVDIHALQTVPPSLINRDDMGAPKTAIFGGVPRQRVSSQSWKRAVRRFFEDEIDKSTVGLRSRKLPENIVSRAIALGSDLTEDQILDGVRQLFKAAKISLVEPKAPKKGEELPEDAEKYPTTGYLLFLSPYQLDRAAQAVVDKNGEKFTKAEAEGILDTKHSVDMALFGRMLADAPAYNIDASVQVAHAISVHESQPEFDYFTAVDDVVEDAEETGAGMIGTTQMMSSTLYRFATVNVDGLVKNLEDTELAHEAVRMFIRAFAESMPTGKQNSFANNTLPELMYVAVRDTRSVSLVNAFEEPVAAVDGSRRQAAATALAREERDIEEAYGMKPLASFVVALGELGTDFEELAEKVTLTELGEAVIRTLAAQEAK
>LR134538.1|VEJ66721.1|1771531_1772236_+|CRISPR-associated-protein
MSYSLLLLLKGPLQSWGDESRYNTRATGNTPSKSGVIGLLAAAQGRQRTDSIEDLVALDFAVRVDQSGTLLRDYQTAQPWQKAPKANASLVTRHFLSDAAFVAAIGSEDKELLEGLQGHLRQPTYPLFLGRRSCPAPINLDLGIVDKPVVEALMAHDAWHATSAHQQERSRDVELPIYRDGKPGEHGVPRQDVPLSFAQEHRRYGWRTVVYAGSKSIVNEKGTANDPFFEAVIS
>LR134538.1|VEJ66722.1|1772237_1772903_+|CRISPR-associated-protein
MATFTKVLINPARRQGRKYLTNPHMLHAAVMHGFPPDCDTSTERILWRLDERGHEHILYVVGPEKPTIDHIVEEAGWDVRPPQSADYDRLLSQITKGQKWNFELVANPTHTIPVQGGKRGKVVAHSTAAKQLEWLHRKAESMGVSFGTLENSSAQVVGKKTLDFHRSRPNGERGDRVHLVTARFSGQLEVVDADKLRATLIGGVGRAKGYGCGLLTLARGQ
>LR134538.1|VEJ66723.1|1772906_1773842_+|CRISPR-associated-protein
MSATPSQSPLDRLLLPRMESRLSFLYVERAVINRDGNALTIKDQRGIAHVPATQLAVVLLGPGTKVTYAAMALLGDAGASVVWVGEKGVRYYAHGRPPAKTSRFAEAHARLWSNQRTRLRCARRMYDMRFPGEEISQLSLSQLRGREGARMKKIYAAEAQRTGVVWTRRNYDPQDFESGDPINRALTEGSAALYGIAHAVIVGLGFIPSLGIVHTGTDRAFVYDIADLYKAEISIPAAFEAVAAIPSGDDLNVRARIRDKVVSTRLMQRMVHDLQDLMEIPEEDAYSDVDLMLWSELEVIAAGVNWSTERF
>LR134538.1|VEJ66724.1|1773848_1774196_+|CRISPR-associated-protein
MIVLVVSAVPAGLRGDLTKWLMEISPGVFVGNPSARIRDLLWERTTELSKDGRALLIYSSNNEQGMEYRTHRHEWEPTDFDGLTLMMRPDNTKPSSYQRRTGWSIARNVRKNRGK
>LR134538.1|VEJ66725.1|1774203_1774473_-|putative-septation-inhibitor-protein
MPKSKINHSSTAYTAGSTANRTPVKINSTGTPLWYKIIMFGLILAGLLWLIVNYLAGQDISFMTELGPWNYGIGFGLFIIGLLMTMGWR
>LR134538.1|VEJ66726.1|1774589_1776611_-|serine/threonine-protein-kinase
MTDIVLADRYRLGDVIGTGGMSEVYEATDVLLGRKVAVKMLRADLARDVNFRERFRREAQNSGKLNHPAIVAVYDTGETPRAGLNTPYIVMELVNGRTLRDIVREDGPLTPSQAAHTLIPVCHALQVSHDAGIIHRDIKPANVMITNTGAVKIMDFGIARALDDATSAMTQTSAVIGTAQYLSPEQARGKLADARSDVYALGCVLYETLTGKPPFEGETPFAVAYQHVQEDPVKPSEYIADLSPTAAINVDAVVLTAMAKHPGDRYQTAQEMCADLERLERNAVTDAARHYVTPTSFATQDPASTTVVPVTQVAELDHAEAGAGIGAGAVPAGAVAGSAAVAGSGGAHAAPRSSNRGLRILAAILTVLVLAVGAGFAIDYFGGGPFSQRSTVSIPKLQNSTQQDAVSQLEKLGLQVNVIEEPNPDIPRGKVIRTNPTDGSNVQRNSTVRLTISSGKEITEVPDLSGKNTADAVKILEAAGLLLDPTVREDSSDTVPKGEIIEVSPAAGSQVSRGSKVSITVSTGVETVRVPVITGMKWDQAEGNLTSLGFKPEVVRVDSVEPAGTVVAVPDEGAEVPKGSSVTVQISNGAMFTVPEITRQTIGDAVRILHDAGWKGNASRLIQAAKVPTVAVTDQNLIASQLPTPGTALRKDAPIEIRLYEFNLAALVPPAQH
>LR134538.1|VEJ66727.1|1776607_1778113_-|serine/threonine-protein-kinase
MTQSQSPDPALQALVGSDYALQWVVGNGGMSTVWLADDLRNQREVAIKVLRPEFSDNEEFLSRFRNEALASEHIDSDNVVRTYDYREVTDDMGRTLCFIVMEYVRGESLADMLARKGRLEEDLALDVLEQAAHGLSIIHRMGMVHRDIKPGNLLITQNGQVKITDFGIAKAAAAVPLTRTGMVVGTAQYVSPEQAQGRDVTAATDVYSLGVVGYEMLVGQRPFTGDSSVSVAIAHINQAPPAMPTSVSAPARELIGIALRKDPAHRYADGNELALAVSATRMGQRPPQPKSAPLQHIAPQPAPTESTYALGATAQPTTVIPATGQVPAAPAAAAYPASTVIPAGTPRQEPEKQSSGWGAGIVVGALAALLLGTAAWAASQGMFDDLFDKTSQSSEPSVPPPPVTATVTETPTPQITTVVPEPLPTSRPEPTPSETKRTPDESHPTSDHQLPSVRPSHNGRPSSQAPQAPTQDADQPAESPAPDTLDSLIENLNKLNQGGAQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR134538_2	2.10\|1767422\|33\|LR134538\|CRISPRCasFinder,CRT,PILER-CR	1767422-1767454	33	LR134538.1	2502462-2502494	1	0.97

1. spacer 2.10|1767422|33|LR134538|CRISPRCasFinder,CRT,PILER-CR matches to position: 2502462-2502494, mismatch: 1, identity: 0.97

ctcctcgaggctgatctcactgtccgtgacggc	CRISPR spacer
cttctcgaggctgatctcactgtccgtgacggc	Protospacer
**.******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	445932-445963	8	0.75
LR134538_3	3.2\|2030306\|32\|LR134538\|CRISPRCasFinder	2030306-2030337	32	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	433898-433929	8	0.75
LR134538_3	3.3\|2030369\|32\|LR134538\|CRISPRCasFinder	2030369-2030400	32	MN855768	Siphoviridae sp. isolate 183, complete genome	16464-16495	8	0.75
LR134538_2	2.1\|1766873\|33\|LR134538\|CRISPRCasFinder,CRT	1766873-1766905	33	NZ_CP016309	Vibrio scophthalmi strain VS-12 plasmid pVS127, complete sequence	95599-95631	9	0.727
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NZ_CP013069	Pannonibacter phragmitetus strain 31801 plasmid p.p-1, complete sequence	191229-191260	9	0.719
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NZ_KU140623	Sinorhizobium sp. M14 plasmid pSinB, complete sequence	93297-93328	9	0.719
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	MN694616	Marine virus AFVG_250M59, complete genome	20093-20124	9	0.719
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	MN693752	Marine virus AFVG_250M58, complete genome	19873-19904	9	0.719
LR134538_3	3.2\|2030306\|32\|LR134538\|CRISPRCasFinder	2030306-2030337	32	NC_008308	Sphingomonas sp. KA1 plasmid pCAR3 DNA, complete sequence	132763-132794	9	0.719
LR134538_3	3.2\|2030306\|32\|LR134538\|CRISPRCasFinder	2030306-2030337	32	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	487839-487870	9	0.719
LR134538_3	3.2\|2030306\|32\|LR134538\|CRISPRCasFinder	2030306-2030337	32	NZ_CP042263	Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence	170086-170117	9	0.719
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NZ_CP009803	Streptomyces sp. FR-008 plasmid pSSFR1, complete sequence	96673-96704	10	0.688
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NZ_CP032313	Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence	21278-21309	10	0.688
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NC_008379	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence	120676-120707	11	0.656
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NZ_CP054034	Rhizobium sp. JKLM13E plasmid pPR13E03, complete sequence	228864-228895	11	0.656
LR134538_3	3.1\|2030243\|32\|LR134538\|CRISPRCasFinder	2030243-2030274	32	NC_016571	Pseudomonas phage OBP, complete genome	130114-130145	11	0.656

1. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
ccgccctcgaccacggcaccacctaccggctg	Protospacer
********.** ***********.* *   *

2. spacer 3.2|2030306|32|LR134538|CRISPRCasFinder matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

cccagcttgtcgacggcaccaaagccgcccaa	CRISPR spacer
ccatcttcgtcgacggcaccagcgccgcccac	Protospacer
**   .*.*************. ********

3. spacer 3.3|2030369|32|LR134538|CRISPRCasFinder matches to MN855768 (Siphoviridae sp. isolate 183, complete genome) position: , mismatch: 8, identity: 0.75

---tcaaactccaagcagccaccggacaaatgggc	CRISPR spacer
cagtca---ctcaagcagccaccggataaacggga	Protospacer
   ***   ..***************.***.***

4. spacer 2.1|1766873|33|LR134538|CRISPRCasFinder,CRT matches to NZ_CP016309 (Vibrio scophthalmi strain VS-12 plasmid pVS127, complete sequence) position: , mismatch: 9, identity: 0.727

tgaggtctgctaggtcattgtcggtgtacccag	CRISPR spacer
ttaagtctgctgggtaattgtcggtgtagtggt	Protospacer
* *.*******.*** ************ . .

5. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NZ_CP013069 (Pannonibacter phragmitetus strain 31801 plasmid p.p-1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
cctccctcaacaacggcacctccggcggtgat	Protospacer
** ***************** ** .   ** .

6. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NZ_KU140623 (Sinorhizobium sp. M14 plasmid pSinB, complete sequence) position: , mismatch: 9, identity: 0.719

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
gcgcgctcaacaacggcatcacccccggtgaa	Protospacer
 *** *************.*****    **

7. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to MN694616 (Marine virus AFVG_250M59, complete genome) position: , mismatch: 9, identity: 0.719

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
agagcctgaataacggcaccacccagcgtata	Protospacer
  . *** **.**************** *.*

8. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to MN693752 (Marine virus AFVG_250M58, complete genome) position: , mismatch: 9, identity: 0.719

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
agagcctgaataacggcaccacccagcgtata	Protospacer
  . *** **.**************** *.*

9. spacer 3.2|2030306|32|LR134538|CRISPRCasFinder matches to NC_008308 (Sphingomonas sp. KA1 plasmid pCAR3 DNA, complete sequence) position: , mismatch: 9, identity: 0.719

cccagcttgtcgacggcaccaaagccgcccaa	CRISPR spacer
tggtctttgtcgacggcaccgatgccgcccag	Protospacer
.    .**************.* ********.

10. spacer 3.2|2030306|32|LR134538|CRISPRCasFinder matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 9, identity: 0.719

cccagcttgtcgacggcaccaaagccgcccaa	CRISPR spacer
gcggtcttgccgacggcacgaaagccgccggt	Protospacer
 * . ****.********* ********* .

11. spacer 3.2|2030306|32|LR134538|CRISPRCasFinder matches to NZ_CP042263 (Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

cccagcttgtcgacggcaccaaagccgcccaa	CRISPR spacer
cgtgccgcgtcgaccgcaccgaagccgcccat	Protospacer
* .. * .****** *****.**********

12. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NZ_CP009803 (Streptomyces sp. FR-008 plasmid pSSFR1, complete sequence) position: , mismatch: 10, identity: 0.688

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
ccgccctcagcaacggcacgaccggagcgaac	Protospacer
*********.********* *** .. . . *

13. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NZ_CP032313 (Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence) position: , mismatch: 10, identity: 0.688

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
cctccctcaacaacggcacctccggcggcggt	Protospacer
** ***************** ** .   .* .

14. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NC_008379 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence) position: , mismatch: 11, identity: 0.656

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
tgagcctcaacaacggcacgacacagccaaat	Protospacer
. . *************** ** ****. . .

15. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NZ_CP054034 (Rhizobium sp. JKLM13E plasmid pPR13E03, complete sequence) position: , mismatch: 11, identity: 0.656

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
ggagcctcaacaacggcacgacacagccaaat	Protospacer
  . *************** ** ****. . .

16. spacer 3.1|2030243|32|LR134538|CRISPRCasFinder matches to NC_016571 (Pseudomonas phage OBP, complete genome) position: , mismatch: 11, identity: 0.656

ccgccctcaacaacggcaccacccagcttgtc	CRISPR spacer
attatatcaagaactgcaccacccagcttcaa	Protospacer
 .  . **** *** **************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

615558 : 663064

Tupanvirus(18.18%)

transposase,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ65646.1\|615558_618225_-\|tRNA	Alanyl-tRNA synthetase	A0A2K9L1X7	Tupanvirus	2.8e-63	35.9
VEJ65647.1\|618386_619745_-	recombination factor protein RarA	G3MBE0	Bacillus_virus	4.2e-92	46.1
VEJ65648.1\|619781_621044_-	Phosphotransferase enzyme family protein	NA	NA	NA	NA
VEJ65649.1\|621166_622966_-\|tRNA	aspartyl-tRNA synthetase	A0A2K9L3L6	Tupanvirus	8.2e-11	30.7
VEJ65650.1\|623193_624078_+	Zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	5.9e-55	48.4
VEJ65651.1\|624158_626813_-	SNF2 family DNA/RNA helicase	A0A160DDK8	Gordonia_phage	2.6e-29	27.0
VEJ65652.1\|626891_628913_-	membrane protein	NA	NA	NA	NA
VEJ65653.1\|628931_629666_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
VEJ65654.1\|629828_630419_+	TetR family transcriptional regulator	NA	NA	NA	NA
VEJ65655.1\|630463_631852_+	L-serine dehydratase	NA	NA	NA	NA
VEJ65656.1\|631923_633195_-\|tRNA	histidyl-tRNA synthetase	NA	NA	NA	NA
VEJ65657.1\|633235_633883_-	Metallo-beta-lactamase superfamily protein	NA	NA	NA	NA
VEJ65658.1\|633901_634399_-	thiol peroxidase	NA	NA	NA	NA
VEJ65659.1\|634542_635385_+	peptidyl-prolyl cis-trans isomerase B	NA	NA	NA	NA
VEJ65660.1\|635541_635829_+	putative secreted protein	NA	NA	NA	NA
VEJ65661.1\|635879_636080_+	Uncharacterised protein	NA	NA	NA	NA
VEJ65662.1\|636628_638908_-	GTP pyrophosphokinase	A0A291L9W9	Bordetella_phage	4.0e-10	35.8
VEJ65663.1\|638966_639521_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.4e-16	35.0
VEJ65664.1\|639576_641328_-	oligopeptide-binding protein OppA	NA	NA	NA	NA
VEJ65665.1\|641396_642509_-	preprotein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.3e-19	27.9
VEJ65666.1\|642509_644288_-	preprotein translocase subunit SecD	NA	NA	NA	NA
VEJ65667.1\|644518_644806_-	preprotein translocase	NA	NA	NA	NA
VEJ65668.1\|644815_645904_-	holliday junction DNA helicase RuvB	NA	NA	NA	NA
VEJ65669.1\|645921_646533_-	holliday junction DNA helicase RuvA	NA	NA	NA	NA
VEJ65670.1\|646571_647063_-	holliday junction resolvase	NA	NA	NA	NA
VEJ65671.1\|647246_647999_-	transcriptional regulator	NA	NA	NA	NA
VEJ65672.1\|648043_648277_+	Uncharacterised protein	NA	NA	NA	NA
VEJ65673.1\|648236_649091_-	acyl-CoA thioesterase II	NA	NA	NA	NA
VEJ65674.1\|649246_650536_+	Predicted integral membrane protein	NA	NA	NA	NA
VEJ65675.1\|650434_650677_-\|transposase	transposase IS3503g	NA	NA	NA	NA
VEJ65676.1\|651123_651498_+\|transposase	transposase-like protein	A0A1B3AZE5	Gordonia_phage	8.4e-11	41.7
VEJ65677.1\|651652_653092_+\|transposase	transposase-like protein	W5R8L2	Staphylococcus_phage	2.0e-28	34.4
VEJ65678.1\|653042_653252_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ65679.1\|653332_653569_-	major facilitator superfamily permease	NA	NA	NA	NA
VEJ65680.1\|653555_653939_-	4-carboxymuconolactone decarboxylase	NA	NA	NA	NA
VEJ65681.1\|653931_655641_-	putative oxidoreductase	NA	NA	NA	NA
VEJ65682.1\|655702_656842_-	putative oxidoreductase	NA	NA	NA	NA
VEJ65683.1\|657208_657505_+	Uncharacterised protein	NA	NA	NA	NA
VEJ65684.1\|657596_658055_-	Uncharacterised protein	NA	NA	NA	NA
VEJ65685.1\|658355_659432_-	replicase RepA	NA	NA	NA	NA
VEJ65686.1\|659848_660553_+	cytochrome c-type biogenesis protein	NA	NA	NA	NA
VEJ65687.1\|661033_661507_-	putative resolvase	M4QQC6	Vibrio_phage	3.3e-20	43.2
VEJ65688.1\|661506_661644_-	Uncharacterised protein	NA	NA	NA	NA
VEJ65689.1\|661707_662235_-\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ65690.1\|662755_663064_-\|transposase	transposase-like protein	NA	NA	NA	NA

DBSCAN-SWA_2

1133780 : 1191729

Bacillus_phage(16.67%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66134.1\|1133780_1134122_-\|protease	ATP-dependent Clp protease adaptor protein ClpS	NA	NA	NA	NA
VEJ66135.1\|1134183_1135497_+	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
VEJ66136.1\|1135528_1137496_+	putative ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	6.8e-67	29.8
VEJ66137.1\|1137497_1138025_+	acetyltransferase GNAT family protein	NA	NA	NA	NA
VEJ66138.1\|1138114_1139215_+	restriction endonuclease	NA	NA	NA	NA
VEJ66139.1\|1139198_1139906_-\|tRNA	peptidyl-tRNA hydrolase	NA	NA	NA	NA
VEJ66140.1\|1139898_1141182_-	Phosphoserine phosphatase	NA	NA	NA	NA
VEJ66141.1\|1141288_1142983_-	Cytochrome C oxidase polypeptide I	NA	NA	NA	NA
VEJ66142.1\|1143345_1144332_-	ribonucleotide-diphosphate reductase subunit beta	A0A160DHK0	Gordonia_phage	6.7e-140	77.9
VEJ66143.1\|1144643_1145129_+	putative ferritin	NA	NA	NA	NA
VEJ66144.1\|1145180_1147340_-	ribonucleotide-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	6.7e-209	51.5
VEJ66145.1\|1147388_1147814_-	ribonucleotide reductase stimulatory protein	H9NCC2	Sphingomonas_phage	8.1e-10	33.6
VEJ66146.1\|1147907_1148141_-	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	4.9e-17	54.5
VEJ66147.1\|1148443_1149316_+	putative phytoene synthase	NA	NA	NA	NA
VEJ66148.1\|1149308_1150835_+	phytoene dehydrogenase	NA	NA	NA	NA
VEJ66149.1\|1150903_1151026_-	50S ribosomal protein L36	NA	NA	NA	NA
VEJ66150.1\|1151179_1152013_+	NAD synthetase	G3MA24	Bacillus_virus	2.9e-80	56.5
VEJ66151.1\|1152009_1152447_-	Pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
VEJ66152.1\|1152598_1154218_-	Rab11 family-interacting protein 3	NA	NA	NA	NA
VEJ66153.1\|1154239_1155508_-	Rab11 family-interacting protein 3	NA	NA	NA	NA
VEJ66154.1\|1156244_1156979_-	putative secreted protein	NA	NA	NA	NA
VEJ66155.1\|1157028_1157532_-	DoxX family membrane protein	NA	NA	NA	NA
VEJ66156.1\|1157528_1159166_-	phosphoglucomutase	NA	NA	NA	NA
VEJ66157.1\|1159231_1159519_+	camphor resistance protein CrcB	NA	NA	NA	NA
VEJ66158.1\|1159515_1159830_+	Protein crcB 2	NA	NA	NA	NA
VEJ66159.1\|1159826_1162391_-	ABC transporter permease protein	NA	NA	NA	NA
VEJ66160.1\|1162391_1163141_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-33	37.9
VEJ66161.1\|1169445_1170702_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
VEJ66162.1\|1170740_1171316_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
VEJ66163.1\|1171368_1172214_-	LuxR family transcriptional regulator	NA	NA	NA	NA
VEJ66164.1\|1172896_1173832_+	cysteine synthase	A0A1X9I5K7	Streptococcus_phage	2.1e-79	52.3
VEJ66165.1\|1173938_1174505_+	serine acetyltransferase	NA	NA	NA	NA
VEJ66166.1\|1174558_1174840_-	predicted acetyltransferase	NA	NA	NA	NA
VEJ66167.1\|1175221_1176298_-	glycerol dehydrogenase	NA	NA	NA	NA
VEJ66168.1\|1176736_1177504_-	iron complex transport system ATP-binding protein	A0A1V0SE00	Indivirus	1.7e-10	26.7
VEJ66169.1\|1177510_1178518_-	vitamin B12-binding protein	NA	NA	NA	NA
VEJ66170.1\|1178538_1179561_-	ferrichrome transport system permease protein fhuB	NA	NA	NA	NA
VEJ66171.1\|1179840_1182420_-	DNA restriction-modification system, restriction enzyme	NA	NA	NA	NA
VEJ66172.1\|1182419_1183490_-	DNA restriction-modification system, DNA methylase	A0A220NUF4	Escherichia_phage	1.2e-14	53.7
VEJ66173.1\|1183618_1184416_-	putative DNA methylase	A0A0F6R5U4	Escherichia_coli_O157_typing_phage	2.9e-24	41.9
VEJ66174.1\|1184996_1185263_-\|transposase	transposase	NA	NA	NA	NA
VEJ66175.1\|1185275_1185545_-\|transposase	transposase	NA	NA	NA	NA
VEJ66176.1\|1185516_1186539_-\|transposase	transposase	NA	NA	NA	NA
VEJ66177.1\|1186921_1188130_+\|transposase	transposase	NA	NA	NA	NA
VEJ66178.1\|1189173_1189725_-	putative secreted protein	NA	NA	NA	NA
VEJ66179.1\|1189898_1190192_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66180.1\|1190349_1191729_-\|transposase	transposase-like protein	A0A1B1P773	Bacillus_phage	1.0e-37	33.7

DBSCAN-SWA_3

1245896 : 1279336

Tupanvirus(40.0%)

protease,transposase,tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66231.1\|1245896_1247288_-\|tRNA	cysteinyl-tRNA synthetase	A0A2K9L6B7	Tupanvirus	4.8e-43	32.8
VEJ66232.1\|1247306_1247789_-	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
VEJ66233.1\|1247781_1248516_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
VEJ66234.1\|1248525_1249107_-	putative transcription factor	NA	NA	NA	NA
VEJ66235.1\|1249377_1249944_+	Lipoprotein LpqE	NA	NA	NA	NA
VEJ66236.1\|1250047_1251436_-	putative secreted protein	NA	NA	NA	NA
VEJ66237.1\|1251560_1251737_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66238.1\|1251753_1253145_+	DNA repair protein RadA	NA	NA	NA	NA
VEJ66239.1\|1253172_1253889_-	putative secreted protein	NA	NA	NA	NA
VEJ66240.1\|1253958_1254588_-	beta-type carbonic anhydrase-like protein	NA	NA	NA	NA
VEJ66241.1\|1254719_1255607_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
VEJ66242.1\|1255603_1255984_-	Uncharacterized conserved protein	NA	NA	NA	NA
VEJ66243.1\|1256093_1256858_-	Inner membrane protein YjjP	NA	NA	NA	NA
VEJ66244.1\|1256988_1257159_-	putative secreted protein	NA	NA	NA	NA
VEJ66245.1\|1257189_1259826_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	9.5e-133	40.5
VEJ66246.1\|1260274_1260730_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66247.1\|1260765_1261404_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66248.1\|1261510_1262305_+	alpha/beta fold family hydrolase	NA	NA	NA	NA
VEJ66249.1\|1262320_1263604_-	Thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.4e-92	45.7
VEJ66250.1\|1263813_1264236_+	Cytidine deaminase	NA	NA	NA	NA
VEJ66251.1\|1264239_1265454_+	putative sodium/nucleoside cotransporter	NA	NA	NA	NA
VEJ66252.1\|1265480_1266920_-\|transposase	transposase-like protein	W5R8L2	Staphylococcus_phage	2.0e-28	34.4
VEJ66253.1\|1267146_1267362_+\|transposase	transposase for insertion sequence	NA	NA	NA	NA
VEJ66254.1\|1267400_1267607_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66255.1\|1267937_1269500_-\|tRNA	lysyl-tRNA synthetase	A0A2K9KZX5	Tupanvirus	3.8e-73	37.3
VEJ66256.1\|1269966_1271685_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66257.1\|1271681_1273232_+	YcaO-like family protein	NA	NA	NA	NA
VEJ66258.1\|1273267_1274752_+	Nitroreductase	NA	NA	NA	NA
VEJ66259.1\|1274748_1277349_+	lantibiotic dehydratase domain-containing protein	NA	NA	NA	NA
VEJ66260.1\|1277348_1278362_+\|bacteriocin	thiopeptide-type bacteriocin biosynthesis domain	NA	NA	NA	NA
VEJ66261.1\|1278358_1279336_+\|protease	Zn-dependent proteases	NA	NA	NA	NA

DBSCAN-SWA_4

1283243 : 1319834

uncultured_virus(20.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66266.1\|1283243_1284212_+\|protease	putative membrane protease subunit	NA	NA	NA	NA
VEJ66267.1\|1284211_1284409_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66268.1\|1284458_1285751_+	sodium/dicarboxylate symporter family protein	NA	NA	NA	NA
VEJ66269.1\|1285758_1286538_-	pantoate-beta-alanine ligase	NA	NA	NA	NA
VEJ66270.1\|1286550_1286958_-	Domain of uncharacterised function (DUF2520)	NA	NA	NA	NA
VEJ66271.1\|1286966_1287173_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66272.1\|1287169_1288078_-	Dihydroneopterin aldolase	NA	NA	NA	NA
VEJ66273.1\|1288088_1288556_-	putative secreted protein	NA	NA	NA	NA
VEJ66274.1\|1288552_1289032_-	putative 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	NA	NA	NA	NA
VEJ66275.1\|1289041_1289407_-	Dihydroneopterin aldolase	NA	NA	NA	NA
VEJ66276.1\|1289412_1290249_-	putative dihydropteroate synthase	S4VNV0	Pandoravirus	2.0e-20	34.0
VEJ66277.1\|1290372_1290687_-	Protein of uncharacterised function, DUF393	NA	NA	NA	NA
VEJ66278.1\|1290689_1291262_-	GTP cyclohydrolase I	A0A1W7AF02	Streptococcus_virus	3.8e-47	55.6
VEJ66279.1\|1291269_1293735_-	cell division protein	G9E4U6	Ostreococcus_lucimarinus_virus	4.0e-109	41.7
VEJ66280.1\|1293866_1294472_-	hypoxanthine-guanine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	5.9e-14	30.8
VEJ66281.1\|1294474_1295317_-\|tRNA	tRNA(Ile)-lysidine synthase	NA	NA	NA	NA
VEJ66282.1\|1295345_1296596_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
VEJ66283.1\|1296660_1297137_+	inorganic pyrophosphatase	NA	NA	NA	NA
VEJ66284.1\|1297293_1297590_+	Rhodanese-related sulfurtransferase	A0A2H4PQR9	Staphylococcus_phage	4.3e-10	40.5
VEJ66285.1\|1297685_1298126_+	multiple antibiotic resistance protein	NA	NA	NA	NA
VEJ66286.1\|1298126_1301969_+	tyrocidine synthetase 3	A0A2K9L3I8	Tupanvirus	4.3e-33	24.1
VEJ66287.1\|1302150_1302375_-	putative surface-anchored fimbrial subunit	NA	NA	NA	NA
VEJ66288.1\|1302722_1303574_+	putative surface-exposed virulence protein bigA	NA	NA	NA	NA
VEJ66289.1\|1303715_1304177_+	putative exported lipase	NA	NA	NA	NA
VEJ66290.1\|1304266_1304677_+	putative secretory lipase	NA	NA	NA	NA
VEJ66291.1\|1304680_1305577_-	Polyphosphate kinase 2	NA	NA	NA	NA
VEJ66292.1\|1305911_1306748_-	putative secreted protein	NA	NA	NA	NA
VEJ66293.1\|1306854_1306983_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66294.1\|1307017_1307173_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66295.1\|1307784_1309425_-	chaperonin GroEL	A0A240F779	uncultured_virus	5.9e-149	54.2
VEJ66296.1\|1309784_1309955_-	Transposase, Mutator family	NA	NA	NA	NA
VEJ66297.1\|1310051_1310465_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66298.1\|1310684_1311653_+	FIC domain-containing protein	D7RWK9	Brochothrix_phage	9.5e-14	30.0
VEJ66299.1\|1311783_1312944_-	RNA-splicing ligase RtcB	A0A0M5M6X2	Mycobacterium_phage	1.1e-133	64.4
VEJ66300.1\|1313854_1314100_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66301.1\|1314121_1314304_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66302.1\|1315169_1315877_+	20kD antigen	NA	NA	NA	NA
VEJ66303.1\|1316185_1316434_-\|transposase	transposase for insertion sequence element	NA	NA	NA	NA
VEJ66304.1\|1316745_1316946_-\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66305.1\|1317065_1318445_-\|transposase	transposase-like protein	A0A1B1P773	Bacillus_phage	1.0e-37	33.7
VEJ66306.1\|1318654_1319122_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66307.1\|1319060_1319834_+\|transposase	transposase-like protein	NA	NA	NA	NA

DBSCAN-SWA_5

1355683 : 1380311

Mycobacterium_phage(16.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66342.1\|1355683_1355941_-\|transposase	transposase-like protein	A0A2P1JR32	Mycobacterium_phage	1.9e-14	54.7
VEJ66343.1\|1355984_1356311_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66344.1\|1356616_1357333_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66345.1\|1357445_1357643_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66346.1\|1358199_1358595_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66347.1\|1358582_1358960_+	YfbU domain	NA	NA	NA	NA
VEJ66348.1\|1359104_1359485_+	Abi-like protein	NA	NA	NA	NA
VEJ66349.1\|1359526_1359670_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66350.1\|1360686_1360908_+	putative secreted protein	NA	NA	NA	NA
VEJ66351.1\|1361112_1361265_+\|transposase	transposase IS1513f	NA	NA	NA	NA
VEJ66352.1\|1361771_1362011_-\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66353.1\|1362104_1362299_-\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66354.1\|1362478_1362652_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66355.1\|1362623_1362749_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66356.1\|1363478_1364738_+	putative secreted protein	NA	NA	NA	NA
VEJ66357.1\|1365162_1365957_-\|transposase	transposase-like protein	A0A1B1P773	Bacillus_phage	5.0e-53	40.4
VEJ66358.1\|1366022_1366505_-\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66359.1\|1366949_1367984_-	fructose-bisphosphate aldolase	NA	NA	NA	NA
VEJ66360.1\|1368102_1369248_-	Glycoside hydrolase family 76 protein	NA	NA	NA	NA
VEJ66361.1\|1369241_1369910_-	23S rRNA guanosine-2'-O-methyltransferase rlmB	NA	NA	NA	NA
VEJ66362.1\|1369902_1370436_-	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	8.6e-17	44.9
VEJ66363.1\|1370491_1371406_-	putative secreted or membrane protein	NA	NA	NA	NA
VEJ66364.1\|1371405_1372416_-	thiosulfate sulfurtransferase	NA	NA	NA	NA
VEJ66365.1\|1372375_1372567_-	Glutamate transport system permease protein gluD	NA	NA	NA	NA
VEJ66366.1\|1372805_1373006_-	putative heat shock protein	NA	NA	NA	NA
VEJ66367.1\|1373143_1373605_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66368.1\|1373582_1373672_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66369.1\|1373668_1373845_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66370.1\|1373964_1376514_-\|protease	putative ATP-dependent protease regulatory subunit	K4FB40	Cronobacter_phage	1.9e-122	37.4
VEJ66371.1\|1376711_1377041_-	resuscitation-promoting factor C	A0A1I9SA30	Rhodococcus_phage	7.4e-27	63.6
VEJ66372.1\|1377169_1377958_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-21	28.1
VEJ66373.1\|1377959_1379528_+	putative integral membrane transport protein	NA	NA	NA	NA
VEJ66374.1\|1379447_1379693_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66375.1\|1380104_1380311_+\|transposase	transposase-like protein	NA	NA	NA	NA

DBSCAN-SWA_6

1485886 : 1554777

Macacine_betaherpesvirus(14.29%)

holin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66451.1\|1485886_1486666_+\|tRNA	tRNA guanine-N7-methyltransferase	NA	NA	NA	NA
VEJ66452.1\|1486662_1487283_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66453.1\|1487297_1489538_+	putative drug exporter of the RND superfamily	NA	NA	NA	NA
VEJ66454.1\|1489539_1490583_+	putative integral membrane protein	NA	NA	NA	NA
VEJ66455.1\|1490579_1490936_+	putative integral membrane protein	NA	NA	NA	NA
VEJ66456.1\|1491075_1491207_+\|transposase	transposase for insertion sequence	NA	NA	NA	NA
VEJ66457.1\|1491157_1491271_+\|transposase	transposase for insertion sequence	NA	NA	NA	NA
VEJ66458.1\|1491359_1491566_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66459.1\|1492045_1495891_-	putative collagen-binding protein	NA	NA	NA	NA
VEJ66460.1\|1496483_1497497_-	endo-beta-N-acetylglucosaminidase F2	NA	NA	NA	NA
VEJ66461.1\|1497674_1499225_-	propionyl-CoA carboxylase subunit beta	NA	NA	NA	NA
VEJ66462.1\|1499236_1503997_-	polyketide synthase involved in mycolic acid biosynthesis	NA	NA	NA	NA
VEJ66463.1\|1504095_1505910_-	acyl-CoA synthetase	NA	NA	NA	NA
VEJ66464.1\|1505984_1506896_-	envelope lipids regulation factor	NA	NA	NA	NA
VEJ66465.1\|1506901_1507417_-	putative secreted protein	NA	NA	NA	NA
VEJ66466.1\|1507416_1509333_-	trehalose corynomycolyl transferase C	A0A2I6B2Q9	Macacine_betaherpesvirus	4.9e-38	37.6
VEJ66467.1\|1509534_1510758_-	mannosyltransferase	NA	NA	NA	NA
VEJ66468.1\|1510803_1511820_-	trehalose corynomycolyl transferase B	A0A2I6AZZ6	Macacine_betaherpesvirus	6.9e-39	37.3
VEJ66469.1\|1511980_1513654_-	arabinofuranosyl transferase C	NA	NA	NA	NA
VEJ66470.1\|1513687_1514665_-	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase	NA	NA	NA	NA
VEJ66471.1\|1514661_1515156_-	putative integral membrane protein	NA	NA	NA	NA
VEJ66472.1\|1515155_1517132_-	putative glycosyltransferase	NA	NA	NA	NA
VEJ66473.1\|1517225_1517741_-	putative integral membrane protein	NA	NA	NA	NA
VEJ66474.1\|1517780_1519358_-	betaine aldehyde dehydrogenase	NA	NA	NA	NA
VEJ66475.1\|1519424_1521650_-\|holin	high-affinity choline transport protein	A0A2I7QNT1	Vibrio_phage	3.3e-17	25.9
VEJ66476.1\|1521921_1523715_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	2.1e-54	28.1
VEJ66477.1\|1523974_1525138_-	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	1.3e-94	46.1
VEJ66478.1\|1525176_1525875_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEJ66479.1\|1525944_1526970_-	putative DNA-binding protein	NA	NA	NA	NA
VEJ66480.1\|1527031_1527238_-	putative nucleotide-binding protein	NA	NA	NA	NA
VEJ66481.1\|1527569_1527806_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66482.1\|1527956_1528268_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66483.1\|1528166_1528559_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66484.1\|1528562_1528757_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66485.1\|1528928_1529282_-\|transposase	transposase	A0A1B0V7I5	Salmonella_phage	2.0e-17	52.0
VEJ66486.1\|1529597_1530389_+	aldo/keto reductase family oxidoreductase	A0A2H4PQR8	Staphylococcus_phage	1.4e-34	34.8
VEJ66487.1\|1530445_1530865_-	Cupin domain	NA	NA	NA	NA
VEJ66488.1\|1530910_1531576_-	putative carboxymuconolactone decarboxylase	NA	NA	NA	NA
VEJ66489.1\|1531630_1531996_-	Uncharacterized protein conserved in bacteria (DUF2255)	NA	NA	NA	NA
VEJ66490.1\|1531985_1532840_-	putative oxidoreductase	A0A2H4PQR8	Staphylococcus_phage	6.4e-38	33.8
VEJ66491.1\|1532884_1533769_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66492.1\|1533930_1535694_+	putative secreted protein	A0A159B6I5	Gordonia_phage	8.6e-05	34.8
VEJ66493.1\|1536310_1536910_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66494.1\|1536936_1538268_-	putative phage resistance protein	NA	NA	NA	NA
VEJ66495.1\|1538362_1538806_-	type I restriction enzyme S subunit	NA	NA	NA	NA
VEJ66496.1\|1538882_1539152_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66497.1\|1539333_1539570_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66498.1\|1539566_1539836_-	mRNA interferase RelE	A0A1S5SCV8	Streptococcus_phage	6.9e-15	41.9
VEJ66499.1\|1539816_1540050_-	Ribbon-helix-helix protein, copG family	NA	NA	NA	NA
VEJ66500.1\|1540132_1540360_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66501.1\|1540361_1540484_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66502.1\|1540789_1540990_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66503.1\|1541012_1541303_+\|transposase	transposase-like protein	Q8W6R2	Burkholderia_virus	9.8e-07	42.0
VEJ66504.1\|1541356_1541527_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66505.1\|1541947_1542208_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66506.1\|1542200_1542473_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66507.1\|1542597_1543977_-\|transposase	transposase-like protein	A0A1B1P773	Bacillus_phage	1.0e-37	33.7
VEJ66508.1\|1544201_1545350_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66509.1\|1545492_1545642_+	putative secreted protein	NA	NA	NA	NA
VEJ66510.1\|1545876_1545984_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66511.1\|1546215_1546587_+	Predicted integral membrane protein	NA	NA	NA	NA
VEJ66512.1\|1546688_1548209_-	glycerol kinase	NA	NA	NA	NA
VEJ66513.1\|1548227_1548968_-	glycerol uptake facilitator protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	1.2e-16	29.3
VEJ66514.1\|1548967_1550692_-	glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
VEJ66515.1\|1550887_1552648_-	putative acyltransferase	NA	NA	NA	NA
VEJ66516.1\|1552660_1553488_-	HAD-family hydrolase	NA	NA	NA	NA
VEJ66517.1\|1553517_1554777_-\|tRNA	seryl-tRNA synthetase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.3e-55	31.1

DBSCAN-SWA_7

1820305 : 1871404

Bacillus_virus(14.29%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66777.1\|1820305_1820980_-\|holin	choline transport system permease protein	NA	NA	NA	NA
VEJ66778.1\|1820986_1821619_-\|holin	choline transport system permease protein	NA	NA	NA	NA
VEJ66779.1\|1821618_1822356_-\|holin	choline transport system ATP-binding protein	G3M9Y6	Bacillus_virus	2.0e-11	25.2
VEJ66780.1\|1822365_1822974_-	anti-sigma factor	NA	NA	NA	NA
VEJ66781.1\|1822970_1823531_-	RNA polymerase sigma factor	NA	NA	NA	NA
VEJ66782.1\|1823581_1823827_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66783.1\|1824057_1825698_+	Protein dipZ	NA	NA	NA	NA
VEJ66784.1\|1825777_1825945_-	Antitoxin Rv0909/MT0933	NA	NA	NA	NA
VEJ66785.1\|1825955_1827302_-	putative peptidase	NA	NA	NA	NA
VEJ66786.1\|1827322_1828375_+	biotin synthase	NA	NA	NA	NA
VEJ66787.1\|1828374_1828635_+	putative aminotransferase	NA	NA	NA	NA
VEJ66788.1\|1829022_1830210_+	ferrisiderophore receptor Irp6A	NA	NA	NA	NA
VEJ66789.1\|1830210_1831254_+	membrane protein permease Irp6B	NA	NA	NA	NA
VEJ66790.1\|1831255_1832014_+	ATP-binding protein Irp6C	G9BWD6	Planktothrix_phage	6.7e-15	25.8
VEJ66791.1\|1832103_1833600_+	putative lipoprotein	NA	NA	NA	NA
VEJ66792.1\|1833617_1834025_+	Uncharacterized conserved protein	NA	NA	NA	NA
VEJ66793.1\|1834039_1835380_+	putative riboflavin biosynthesis protein	A0A1V0SGL1	Hokovirus	1.0e-34	26.7
VEJ66794.1\|1835402_1835822_+	Protein of uncharacterised function (DUF2871)	NA	NA	NA	NA
VEJ66795.1\|1835808_1836876_-	Inositol-3-phosphate synthase	A0A0H4IPK5	Stenotrophomonas_phage	6.9e-74	42.6
VEJ66796.1\|1837122_1837881_-	Fe(2+)/Mn(2+) transporter pcl1	NA	NA	NA	NA
VEJ66797.1\|1838136_1838757_-	putative lipase	NA	NA	NA	NA
VEJ66798.1\|1838853_1839432_+	putative dehydrogenase	NA	NA	NA	NA
VEJ66799.1\|1839436_1841185_-	ATP-dependent DNA helicase	NA	NA	NA	NA
VEJ66800.1\|1842402_1843014_+	putative siderophore binding protein	NA	NA	NA	NA
VEJ66801.1\|1843010_1844009_-	ROK-family transcriptional regulator	NA	NA	NA	NA
VEJ66802.1\|1844376_1845747_+	iron-regulated membrane protein	NA	NA	NA	NA
VEJ66803.1\|1845897_1846983_+	Rossmann fold nucleotide-binding protein	A0A1G5S9X4	Enterococcus_phage	2.3e-16	35.7
VEJ66804.1\|1846946_1848608_+	Bacterial protein of uncharacterised function (DUF885)	NA	NA	NA	NA
VEJ66805.1\|1848644_1849082_+	MarR family transcriptional regulator	NA	NA	NA	NA
VEJ66806.1\|1849059_1850112_-	ammonia monooxygenase	NA	NA	NA	NA
VEJ66807.1\|1850116_1850602_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66808.1\|1850699_1851470_+	Sulfite exporter TauE/SafE	NA	NA	NA	NA
VEJ66809.1\|1851459_1853805_-	ATP-dependent helicase	A0A1V0SDF7	Indivirus	1.6e-27	27.2
VEJ66810.1\|1853794_1854394_-	maltose O-acetyltransferase	NA	NA	NA	NA
VEJ66811.1\|1854413_1855106_+	putative DNA repair protein	NA	NA	NA	NA
VEJ66812.1\|1855128_1855746_+	DNA-3-methyladenine glycosidase I	NA	NA	NA	NA
VEJ66813.1\|1855702_1856479_+	putative oxidoreductase	NA	NA	NA	NA
VEJ66814.1\|1856738_1857497_+	putative lipoprotein	NA	NA	NA	NA
VEJ66815.1\|1857854_1858154_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66816.1\|1858346_1858712_+\|transposase	transposase-like protein	NA	NA	NA	NA
VEJ66817.1\|1859135_1860074_+	SMI1 / KNR4 family	NA	NA	NA	NA
VEJ66818.1\|1860550_1860817_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66819.1\|1860922_1862227_+	trehalose corynomycolyl transferase	A0A1I9SA50	Rhodococcus_phage	1.4e-23	35.4
VEJ66820.1\|1862266_1862473_+	putative secreted protein	NA	NA	NA	NA
VEJ66821.1\|1862490_1863159_+	putative secreted protein	NA	NA	NA	NA
VEJ66822.1\|1863278_1867118_+	putative secreted protein	NA	NA	NA	NA
VEJ66823.1\|1867211_1867619_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66824.1\|1867711_1868176_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66825.1\|1868283_1868535_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66826.1\|1868546_1869392_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66827.1\|1869391_1870360_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66828.1\|1870417_1870720_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66829.1\|1870738_1871404_+\|transposase	transposase-like protein	NA	NA	NA	NA

DBSCAN-SWA_8

1898228 : 1944485

Corynebacterium_phage(83.78%)

protease,capsid,transposase,tail,terminase,holin,head,integrase

attL 1905086:1905119|attR 1944705:1944738

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ66858.1\|1898228_1899668_-\|transposase	transposase-like protein	W5R8L2	Staphylococcus_phage	2.0e-28	34.4
VEJ66859.1\|1899784_1900816_+	ABC-type iron uptake system substrate-binding protein	NA	NA	NA	NA
VEJ66860.1\|1900922_1901702_-	O-antigen export system ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.9e-10	26.5
VEJ66861.1\|1901720_1902626_-	O-antigen export system permease protein rfbA	NA	NA	NA	NA
VEJ66862.1\|1902717_1903911_+	cysteine desulfurase	NA	NA	NA	NA
VEJ66863.1\|1903907_1904855_-	putative quinone oxidoreductase	NA	NA	NA	NA
1905086:1905119	attL	NA	NA	NA	NA
VEJ66864.1\|1905197_1906232_-	putative aminotransferase	A0A1X6WGT4	Pacmanvirus	8.3e-16	25.4
VEJ66865.1\|1907029_1908604_+	Sodium-dependent dicarboxylate transporter sdcS	NA	NA	NA	NA
VEJ66866.1\|1908968_1909976_+	phage protein	A0A220NQR4	Corynebacterium_phage	1.4e-108	58.2
VEJ66867.1\|1910204_1911431_-\|integrase	putative phage integrase	A0A1W6JRD7	Corynebacterium_phage	7.6e-218	90.7
VEJ66868.1\|1911530_1912553_-	putative transcriptional regulator	NA	NA	NA	NA
VEJ66869.1\|1912564_1913128_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66870.1\|1913222_1913630_-	Domain of uncharacterised function (DUF955)	A0A1W6JRC2	Corynebacterium_phage	3.8e-73	98.5
VEJ66871.1\|1913639_1914131_-	DNA-binding protein	A0A1W6JRB0	Corynebacterium_phage	5.2e-69	85.3
VEJ66872.1\|1914250_1914487_+	putative transcriptional regulator	A0A1W6JRC7	Corynebacterium_phage	1.2e-34	98.7
VEJ66873.1\|1914533_1915001_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66874.1\|1915224_1915605_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66875.1\|1915792_1916059_-	Uncharacterised protein	NA	NA	NA	NA
VEJ66876.1\|1916152_1916971_+	putative anti-repressor protein	A0A1W6JRI1	Corynebacterium_phage	9.2e-135	87.5
VEJ66877.1\|1916990_1917191_+	Helix-turn-helix domain	NA	NA	NA	NA
VEJ66878.1\|1917187_1917430_+	Uncharacterised protein	A0A1W6JRC8	Corynebacterium_phage	8.4e-20	59.0
VEJ66879.1\|1917441_1917666_+	Uncharacterised protein	A0A1W6JRD0	Corynebacterium_phage	4.9e-06	44.4
VEJ66880.1\|1917662_1917809_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66881.1\|1918078_1918228_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66882.1\|1918224_1918926_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66883.1\|1918922_1919333_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66884.1\|1919361_1920570_+	Uncharacterised protein	A0A220NQT1	Corynebacterium_phage	2.6e-133	66.2
VEJ66885.1\|1920562_1921150_+	Uncharacterised protein	A0A1W6JRC6	Corynebacterium_phage	1.0e-58	59.5
VEJ66886.1\|1921270_1921552_+	Uncharacterised protein	A0A1W6JRD4	Corynebacterium_phage	1.3e-51	100.0
VEJ66887.1\|1921704_1922049_+	Uncharacterised protein	A0A1W6JRH9	Corynebacterium_phage	3.5e-19	50.5
VEJ66888.1\|1922038_1923640_+\|terminase	terminase	A0A1W6JRF6	Corynebacterium_phage	3.6e-159	77.2
VEJ66889.1\|1923652_1924903_+	phage protein	A0A1W6JRE1	Corynebacterium_phage	3.3e-224	92.8
VEJ66890.1\|1924899_1925943_+\|head,protease	putative phage prohead protease	A0A1W6JRD9	Corynebacterium_phage	3.4e-182	91.7
VEJ66891.1\|1925939_1927190_+\|capsid	putative phage capsid protein	A0A1W6JRF1	Corynebacterium_phage	3.7e-204	88.5
VEJ66892.1\|1927189_1927390_+	Uncharacterised protein	A0A1W6JRE2	Corynebacterium_phage	2.3e-15	65.2
VEJ66893.1\|1927411_1927894_+	Uncharacterised protein	A0A1W6JRD8	Corynebacterium_phage	1.6e-83	93.8
VEJ66894.1\|1927890_1928253_+	Uncharacterised protein	A0A1W6JRD5	Corynebacterium_phage	2.1e-59	93.3
VEJ66895.1\|1928245_1928512_+	Uncharacterised protein	A0A1W6JRE6	Corynebacterium_phage	1.5e-38	94.3
VEJ66896.1\|1928501_1928879_+	Uncharacterised protein	A0A1W6JRI9	Corynebacterium_phage	5.8e-60	89.6
VEJ66897.1\|1928907_1929855_+\|tail	phage major tail protein	A0A1W6JRH0	Corynebacterium_phage	5.6e-152	83.8
VEJ66898.1\|1929951_1930329_+	Uncharacterised protein	A0A1W6JRK1	Corynebacterium_phage	1.3e-59	96.0
VEJ66899.1\|1930397_1930700_+	Uncharacterised protein	A0A1W6JRF2	Corynebacterium_phage	2.0e-31	91.3
VEJ66900.1\|1930709_1936352_+	immunity-specific protein Beta241	A0A1W6JRG1	Corynebacterium_phage	0.0e+00	84.2
VEJ66901.1\|1936361_1937114_+	immunity-specific protein Beta201	A0A1W6JRF0	Corynebacterium_phage	5.5e-126	87.2
VEJ66902.1\|1937114_1937975_+	immunity-specific protein Beta286	Q37921	Corynephage	4.4e-164	99.0
VEJ66903.1\|1937974_1939090_+	immunity-specific protein Beta371	Q37922	Corynephage	8.6e-160	94.6
VEJ66904.1\|1939089_1940286_+	laminin subunit beta-2	A0A1W6JRF8	Corynebacterium_phage	1.4e-46	61.6
VEJ66905.1\|1940674_1941412_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JRK9	Corynebacterium_phage	1.6e-138	92.7
VEJ66906.1\|1941411_1941648_+\|holin	holin	A0A1W6JRG0	Corynebacterium_phage	2.5e-29	88.5
VEJ66907.1\|1941653_1942118_+	Uncharacterised protein	A0A1W6JRF4	Corynebacterium_phage	4.8e-56	72.2
VEJ66908.1\|1942114_1942453_+	putative secreted protein	A0A1W6JRH1	Corynebacterium_phage	5.4e-49	89.3
VEJ66909.1\|1942802_1944485_+	diphtheria toxin	A7UH54	Corynephage	0.0e+00	98.0
1944705:1944738	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2041972 : 2086144

uncultured_Mediterranean_phage(16.67%)

protease,transposase,integrase

attL 2035576:2035592|attR 2087960:2087976

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2035576:2035592	attL	NA	NA	NA	NA
VEJ66992.1\|2041972_2043157_+\|protease	serine protease (mycosin)	NA	NA	NA	NA
VEJ66993.1\|2043153_2044092_-	putative hydrolase	NA	NA	NA	NA
VEJ66994.1\|2044179_2044680_-	hypothetical membrane protein	NA	NA	NA	NA
VEJ66995.1\|2044807_2045461_+	Uncharacterised protein	NA	NA	NA	NA
VEJ66996.1\|2045398_2046256_-	phosphoserine phosphatase	NA	NA	NA	NA
VEJ66997.1\|2046727_2047765_+	putative morphological differentiation-related protein	NA	NA	NA	NA
VEJ66998.1\|2047757_2048855_+	GSPII_E, type II/IV secretion system protein	NA	NA	NA	NA
VEJ66999.1\|2048851_2049598_+	hypothetical membrane protein	NA	NA	NA	NA
VEJ67000.1\|2049597_2050176_+	putative secreted protein	NA	NA	NA	NA
VEJ67001.1\|2050199_2050397_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67002.1\|2050393_2050669_+	putative secreted protein	NA	NA	NA	NA
VEJ67003.1\|2050665_2050992_+	putative secreted protein	NA	NA	NA	NA
VEJ67004.1\|2050981_2053297_-	ATP-dependent RNA helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	8.9e-10	29.3
VEJ67005.1\|2053964_2054582_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-09	32.4
VEJ67006.1\|2054578_2055286_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-13	28.7
VEJ67007.1\|2055282_2056530_+	putative ABC transporter permease protein	NA	NA	NA	NA
VEJ67008.1\|2056526_2056922_+	ABC-transport solute-binding protein	NA	NA	NA	NA
VEJ67009.1\|2056903_2058013_+	ABC-transport solute-binding protein	NA	NA	NA	NA
VEJ67010.1\|2058019_2059774_+	ABC-transport permease protein	NA	NA	NA	NA
VEJ67011.1\|2059751_2061245_-	nucleoside-diphosphate-sugar epimerase	NA	NA	NA	NA
VEJ67012.1\|2061385_2064280_+	DNA topoisomerase I	A0A1V0SCS0	Indivirus	2.2e-98	36.1
VEJ67013.1\|2064429_2065038_-	Phosphatidylglycerophosphatase B	NA	NA	NA	NA
VEJ67014.1\|2065466_2067443_-	metal-nicotianamine transporter YSL2	NA	NA	NA	NA
VEJ67015.1\|2067529_2069566_-	exo-alpha-sialidase	NA	NA	NA	NA
VEJ67016.1\|2069672_2070572_+	UDP-N-acetylglucosamine diphosphorylase	NA	NA	NA	NA
VEJ67017.1\|2070588_2072010_-	adenylate cyclase	A0A1B1IWY2	uncultured_Mediterranean_phage	1.7e-19	31.7
VEJ67018.1\|2072011_2073379_+	DNA polymerase III delta prime subunit	S5WKH4	Pseudomonas_phage	3.8e-08	28.4
VEJ67019.1\|2073784_2074027_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67020.1\|2074275_2074683_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67021.1\|2074686_2075451_-	tyrosine recombinase XerC	A0A1W6JRD7	Corynebacterium_phage	3.1e-76	60.3
VEJ67022.1\|2075676_2075886_-\|integrase	putative phage integrase	A0A1W6JRD7	Corynebacterium_phage	4.7e-19	66.7
VEJ67023.1\|2076070_2076607_-	putative DNA-binding protein	NA	NA	NA	NA
VEJ67024.1\|2077040_2077565_+	putative secreted protein	NA	NA	NA	NA
VEJ67025.1\|2077571_2077898_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67026.1\|2078002_2079352_+\|transposase	transposase IS3508a	A0A218MNI5	uncultured_virus	6.8e-34	36.1
VEJ67027.1\|2079723_2080839_-	FIC domain-containing protein	D7RWK9	Brochothrix_phage	4.2e-21	28.1
VEJ67028.1\|2080877_2081576_+	putative alkylated DNA repair protein	NA	NA	NA	NA
VEJ67029.1\|2081633_2082440_-\|protease	putative secreted protease	NA	NA	NA	NA
VEJ67030.1\|2083166_2083334_-	Uncharacterised protein	NA	NA	NA	NA
VEJ67031.1\|2083398_2083908_-	putative secreted protein	NA	NA	NA	NA
VEJ67032.1\|2084505_2084754_-\|transposase	transposase-like protein	A0A0N7C1X7	Escherichia_phage	1.1e-06	60.0
VEJ67033.1\|2084704_2086144_-\|transposase	transposase-like protein	W5R8L2	Staphylococcus_phage	2.0e-28	34.4
2087960:2087976	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2501666 : 2527650

Corynebacterium_phage(55.56%)

protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ67455.1\|2501666_2502335_+	DNA methylase N-4	Q855N6	Mycobacterium_virus	1.3e-38	43.8
VEJ67456.1\|2502404_2502590_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67457.1\|2502662_2503229_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67458.1\|2503343_2504045_+	primosome assembly protein PriA	A0A1P8D5W0	Corynebacterium_phage	7.5e-45	33.3
VEJ67459.1\|2504365_2505157_+	Uncharacterised protein	A0A142KC03	Gordonia_phage	9.4e-60	61.2
VEJ67460.1\|2505236_2505545_+	Uncharacterised protein	A0A142KC07	Gordonia_phage	9.1e-11	57.4
VEJ67461.1\|2505557_2507111_+	putative phage associated protein	A0A1P8D5K9	Corynebacterium_phage	1.6e-92	44.3
VEJ67462.1\|2507123_2508434_+	Mu-like prophage protein gp29	A0A142K8P5	Gordonia_phage	2.4e-97	48.7
VEJ67463.1\|2508435_2509608_+\|protease	ATP-dependent Clp protease proteolytic subunit 2	A0A1P8D5M0	Corynebacterium_phage	4.3e-37	29.9
VEJ67464.1\|2509627_2510086_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67465.1\|2510105_2511026_+	Uncharacterised protein	G9FH31	Rhodococcus_phage	2.7e-42	34.4
VEJ67466.1\|2511035_2511395_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67467.1\|2511416_2511848_+	Phage protein Gp19/Gp15/Gp42	A0A1L6BZF5	Pasteurella_phage	3.6e-13	39.2
VEJ67468.1\|2511847_2512180_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67469.1\|2512179_2512470_+	Uncharacterised protein	A0A1L6BZF3	Pasteurella_phage	8.8e-08	33.7
VEJ67470.1\|2512469_2512862_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67471.1\|2512858_2513767_+\|tail	phage major tail protein	A0A1W6JRH0	Corynebacterium_phage	2.5e-16	53.5
VEJ67472.1\|2513870_2514164_+	Uncharacterised protein	A0A1P8D5N6	Corynebacterium_phage	4.3e-10	38.1
VEJ67473.1\|2514205_2514529_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67474.1\|2514540_2520153_+	laminin subunit gamma-1	A0A1W6JRG1	Corynebacterium_phage	1.1e-77	33.8
VEJ67475.1\|2520214_2520970_+	immunity-specific protein beta201	NA	NA	NA	NA
VEJ67476.1\|2520936_2521824_+	immunity-specific protein Beta286	Q37921	Corynephage	1.5e-53	41.5
VEJ67477.1\|2521820_2523098_+	immunity-specific protein Beta371	A0A1P8D5M2	Corynebacterium_phage	5.8e-27	39.1
VEJ67478.1\|2523113_2524307_+\|tail	phage tail fiber	A0A1W6JRF8	Corynebacterium_phage	4.4e-69	64.7
VEJ67479.1\|2524308_2524944_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67480.1\|2525033_2526512_+	basic 30 kDa endochitinase	A7IYC3	Corynebacterium_phage	3.7e-57	55.9
VEJ67481.1\|2526498_2526861_+	putative secreted protein	NA	NA	NA	NA
VEJ67482.1\|2526866_2527304_+	Uncharacterised protein	NA	NA	NA	NA
VEJ67483.1\|2527287_2527650_+	Uncharacterised protein	A0A1W6JQC8	Corynebacterium_phage	3.8e-24	49.1

Anti-CRISPR protein detection

Acr_ID: LR134538.1|VEJ67472.1|2513870_2514164_+|Uncharacterised-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

LR134538.1|VEJ67472.1|2513870_2514164_+|Uncharacterised-protein

2513870_2514164_+

97 aa aa

2501666-2527650

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
LR134538_2	TypeI-E	2.10\|1767422\|33\|LR134538\|CRISPRCasFinder,CRT,PILER-CR	1767422-1767454	33	2502462-2502494	1

1. spacer 2.10|1767422|33|LR134538|CRISPRCasFinder,CRT,PILER-CR matches to LR134538 position: 2502462-2502494, mismatch: 1

ctcctcgaggctgatctcactgtccgtgacggc	CRISPR spacer
cttctcgaggctgatctcactgtccgtgacggc	Protospacer
**.******************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134538

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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