CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR216065	Streptococcus pneumoniae isolate 55896440-41bd-11e5-998e-3c4a9275d6c6 genome assembly, chromosome: 1	1 crisprs	PrimPol,cas3,DinG,DEDDh,RT	2	2	21	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR216065_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR216065_1

76470-76565

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR216065_1

>merge|LR216065|1|76470-76565|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>LR216065|1|1|76470-76565|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
LR216065.1\|VFI38846.1\|76125_76452_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
LR216065.1\|VFI38832.1\|74641_75553_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|372574
LR216065.1\|VFI38895.1\|82791_83463_-\|putative-L-serine-dehydratase-beta-subunit	unknown	unknown	gnl\|CDD\|224674
LR216065.1\|VFI38902.1\|83704_84292_+\|LysM-domain-protein	unknown	unknown	gnl\|CDD\|212030
LR216065.1\|VFI38783.1\|67071_67293_+\|surface-anchored-protein	unknown	unknown	unknown
LR216065.1\|VFI38910.1\|85089_85377_+\|bacteriocin,-putative	unknown	unknown	gnl\|CDD\|273735
LR216065.1\|VFI38839.1\|75545_76139_-\|membrane-protein	unknown	unknown	gnl\|CDD\|227053
LR216065.1\|VFI38825.1\|73519_74584_-\|response-regulator-(Homolog-to-RR11-Spn)	unknown	unknown	gnl\|CDD\|374284
LR216065.1\|VFI38873.1\|80949_81207_-\|chlorohydrolase	unknown	unknown	unknown
LR216065.1\|VFI38818.1\|72587_73448_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|339103
LR216065.1\|VFI38854.1\|76590_77757_-\|cyanate-permease	unknown	unknown	gnl\|CDD\|340897
LR216065.1\|VFI38790.1\|67611_68541_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
LR216065.1\|VFI38880.1\|81256_81889_-\|phosphatase	unknown	unknown	gnl\|CDD\|319798
LR216065.1\|VFI38887.1\|81910_82783_-\|L-serine-dehydratase,-alpha-subunit	unknown	unknown	gnl\|CDD\|129801
LR216065.1\|VFI38811.1\|71326_72313_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
LR216065.1\|VFI38858.1\|77907_78972_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|133016
LR216065.1\|VFI38797.1\|68554_69478_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
LR216065.1\|VFI38866.1\|79013_80864_+\|nucleoside-diphosphate-sugar-isomerase	unknown	unknown	gnl\|CDD\|224011
LR216065.1\|VFI38917.1\|85428_87537_+\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|273736
LR216065.1\|VFI38804.1\|69581_71057_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|378792

Protein	Function_ID	Function_description	E-value
LR216065.1\|VFI38846.1\|76125_76452_-\|transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19
LR216065.1\|VFI38832.1\|74641_75553_-\|Uncharacterised-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	2.81991e-30
LR216065.1\|VFI38895.1\|82791_83463_-\|putative-L-serine-dehydratase-beta-subunit	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
LR216065.1\|VFI38902.1\|83704_84292_+\|LysM-domain-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	5.22512e-13
LR216065.1\|VFI38910.1\|85089_85377_+\|bacteriocin,-putative	gnl\|CDD\|273735	TIGR01653, hypothetical_protein, bacteriocin, lactococcin 972 family. This model represents bacteriocins related to lactococcin 972. Members tend to be found in association with a seven transmembrane putative immunity protein. [Cellular processes, Toxin production and resistance].	6.91587e-26
LR216065.1\|VFI38839.1\|75545_76139_-\|membrane-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	3.58368e-63
LR216065.1\|VFI38825.1\|73519_74584_-\|response-regulator-(Homolog-to-RR11-Spn)	gnl\|CDD\|374284	pfam16001, DUF4775, Domain of unknown function (DUF4775). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.	5.00275e-05
LR216065.1\|VFI38818.1\|72587_73448_+\|Uncharacterised-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	2.9561e-118
LR216065.1\|VFI38854.1\|76590_77757_-\|cyanate-permease	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.12983e-126
LR216065.1\|VFI38790.1\|67611_68541_+\|ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
LR216065.1\|VFI38880.1\|81256_81889_-\|phosphatase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.4095e-97
LR216065.1\|VFI38887.1\|81910_82783_-\|L-serine-dehydratase,-alpha-subunit	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	2.65225e-106
LR216065.1\|VFI38811.1\|71326_72313_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
LR216065.1\|VFI38858.1\|77907_78972_+\|glycosyl-transferase	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	7.45156e-110
LR216065.1\|VFI38797.1\|68554_69478_+\|ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69
LR216065.1\|VFI38866.1\|79013_80864_+\|nucleoside-diphosphate-sugar-isomerase	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
LR216065.1\|VFI38917.1\|85428_87537_+\|bacteriocin-immunity-protein	gnl\|CDD\|273736	TIGR01654, unnamed_protein_product, bacteriocin-associated integral membrane (putative immunity) protein. This model represents a family of integral membrane proteins, most of which are about 650 residues in size and predicted to span the membrane seven times. Nearly half of the members of this family are found in association with a member of the lactococcin 972 family of bacteriocins (TIGR01653). Others may be associated with uncharacterized proteins that may also act as bacteriocins. Although this protein is suggested to be an immunity protein, and the bacteriocin is suggested to be exported by a Sec-dependent process, the role of this protein is unclear. [Cellular processes, Toxin production and resistance].	0
LR216065.1\|VFI38804.1\|69581_71057_+\|extracellular-solute-binding-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.40325e-44

>LR216065.1|VFI38846.1|76125_76452_-|transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>LR216065.1|VFI38839.1|75545_76139_-|membrane-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGIEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGDQHA
>LR216065.1|VFI38832.1|74641_75553_-|Uncharacterised-protein
MRKLTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLAMSKEPVYDSRMEELTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDKTLSLTDKKLSESPFLSSGIGGILHIASSYSRRFEEVILQLPKGRSLKGINVSTNRGQTTIINASLENATLHTNSYILRIEGSRIKNSKLTTPNIVNIFDTDLTDSQLESTENHFHAENIKVYGKVELSSKNALSIMLTQKESQEINLDLSSHYGPIYQLSRDESQHHPNELSNPYKTEKTDVKGQLIARAEDYISLETTANKP
>LR216065.1|VFI38825.1|73519_74584_-|response-regulator-(Homolog-to-RR11-Spn)
MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEKNTQVEEEVSQAKAELENQQEEKIETPEDSEARTETEEKKASNSTEEEQDLSKETEKVTIAEESQEALSQQKATTKEPLLLSKSLESPYIPDQAPKSTDKWKEQVLDFWSWLVEALKSPTSKLETSSTHSYTAFLFLILFSASSFFFSIYHIKHAYYGHIATMHNHFPEQFASLNLFSIISILVATTLFFFSFLLGSFVVRRFIYQEKDWTLEKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLINGVIILLFFVAEVALIGDYLRILAFL
>LR216065.1|VFI38818.1|72587_73448_+|Uncharacterised-protein
MTKTFFIPNKQSILGEQEILTAKSILALVDGLESHSYDVVYLRQPLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYTGTEIEGLDGFDFEAYFQASIQAYLADNAARFTICQGIFNPIFFSRENLKSFLGEDGWAQFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTILPREPFVPAVYMEQLVDKEVQWEIDLVQITGDGSKPEDYEAIARLDYATFLEVLPPSFYHQLDANQLEVQPILDKDFKTLAQEE
>LR216065.1|VFI38811.1|71326_72313_+|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDHETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSEHELTQAEVVERLAAIGESLDQAATV
>LR216065.1|VFI38804.1|69581_71057_+|extracellular-solute-binding-protein
MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEVLNLLNTNPELLNGLVYGPEGKNWEKLAGKENRVKVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIEDSKKQLAEAKESPALGFIFNTDNVKSEISAISNTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYDKVLNEMQKQYDEFLKNKK
>LR216065.1|VFI38797.1|68554_69478_+|ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>LR216065.1|VFI38790.1|67611_68541_+|ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>LR216065.1|VFI38783.1|67071_67293_+|surface-anchored-protein
MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLFLADEKGSEHTEAEVIDNLKEVIAKLKANA
>LR216065.1|VFI38854.1|76590_77757_-|cyanate-permease
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL
>LR216065.1|VFI38858.1|77907_78972_+|glycosyl-transferase
MTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML
>LR216065.1|VFI38866.1|79013_80864_+|nucleoside-diphosphate-sugar-isomerase
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>LR216065.1|VFI38873.1|80949_81207_-|chlorohydrolase
MKIKEQTRKLAAGCSKHCFEVADRTDEVSSKHCFKVVDGTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNHIRQGDVDVV
>LR216065.1|VFI38880.1|81256_81889_-|phosphatase
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>LR216065.1|VFI38887.1|81910_82783_-|L-serine-dehydratase,-alpha-subunit
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>LR216065.1|VFI38895.1|82791_83463_-|putative-L-serine-dehydratase-beta-subunit
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>LR216065.1|VFI38902.1|83704_84292_+|LysM-domain-protein
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETVSAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>LR216065.1|VFI38910.1|85089_85377_+|bacteriocin,-putative
MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFGYSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE
>LR216065.1|VFI38917.1|85428_87537_+|bacteriocin-immunity-protein
MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDLYLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLDFTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEMDKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQPMMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPMLWLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTALLIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFYQDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTGIKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFPYSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKLSDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRDIITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVLGLASRMEKRSLVELLKGGIL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR216065_2	2.1\|1604286\|54\|LR216065\|CRT	1604286-1604339	54	LR216065.1	1604742-1604795	0	1.0
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604490-1604507	0	1.0
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604610-1604627	0	1.0
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604706-1604723	0	1.0
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605198-1605215	0	1.0
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605282-1605299	0	1.0
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604538-1604555	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604946-1604963	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604982-1604999	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605054-1605071	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605090-1605107	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605126-1605143	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605222-1605239	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605306-1605323	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605402-1605419	1	0.944
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604514-1604531	2	0.889
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1604802-1604819	2	0.889
LR216065_2	2.3\|1604406\|18\|LR216065\|CRT	1604406-1604423	18	LR216065.1	1605150-1605167	2	0.889

1. spacer 2.1|1604286|54|LR216065|CRT matches to position: 1604742-1604795, mismatch: 0, identity: 1.0

cgacgcgcttgttgatgctgatgtacttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
cgacgcgcttgttgatgctgatgtacttgctgaggtcgacgcgcttgttgatgc	Protospacer
******************************************************

2. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604490-1604507, mismatch: 0, identity: 1.0

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgatgc	Protospacer
******************

3. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604610-1604627, mismatch: 0, identity: 1.0

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgatgc	Protospacer
******************

4. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604706-1604723, mismatch: 0, identity: 1.0

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgatgc	Protospacer
******************

5. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605198-1605215, mismatch: 0, identity: 1.0

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgatgc	Protospacer
******************

6. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605282-1605299, mismatch: 0, identity: 1.0

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgatgc	Protospacer
******************

7. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604538-1604555, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

8. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604946-1604963, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

9. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604982-1604999, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

10. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605054-1605071, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgaagc	Protospacer
*************** **

11. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605090-1605107, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

12. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605126-1605143, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcgcttgttgaagc	Protospacer
*************** **

13. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605222-1605239, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

14. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605306-1605323, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

15. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605402-1605419, mismatch: 1, identity: 0.944

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgatgc	Protospacer
******.***********

16. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604514-1604531, mismatch: 2, identity: 0.889

acttgcgcttgttgatgc	CRISPR spacer
acttacacttgttgatgc	Protospacer
****.*.***********

17. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1604802-1604819, mismatch: 2, identity: 0.889

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgaagc	Protospacer
******.******** **

18. spacer 2.3|1604406|18|LR216065|CRT matches to position: 1605150-1605167, mismatch: 2, identity: 0.889

acttgcgcttgttgatgc	CRISPR spacer
acttgcacttgttgacgc	Protospacer
******.********.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NZ_CP051294	Mesorhizobium sp. NZP2077 plasmid pMSNZP2077A, complete sequence	29162-29191	5	0.833
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NZ_CP033363	Mesorhizobium sp. NZP2077 plasmid pMSNZP2077NSa, complete sequence	29162-29191	5	0.833
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NZ_CP051294	Mesorhizobium sp. NZP2077 plasmid pMSNZP2077A, complete sequence	29162-29191	5	0.833
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NZ_CP033363	Mesorhizobium sp. NZP2077 plasmid pMSNZP2077NSa, complete sequence	29162-29191	5	0.833
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NC_007766	Rhizobium etli CFN 42 plasmid p42f, complete sequence	592343-592372	6	0.8
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	1655094-1655123	6	0.8
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NC_007766	Rhizobium etli CFN 42 plasmid p42f, complete sequence	592343-592372	6	0.8
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	1655094-1655123	6	0.8
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NZ_CP016722	Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11C, complete sequence	8166-8195	7	0.767
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NC_004444	Pseudomonas resinovorans plasmid pCAR1, complete sequence	15836-15865	7	0.767
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NC_021506	Pseudomonas resinovorans NBRC 106553 plasmid pCAR1.3, complete sequence	15836-15865	7	0.767
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NC_011838	Pseudomonas putida plasmid pCAR1.2, complete sequence	15836-15865	7	0.767
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NZ_CP016722	Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11C, complete sequence	8166-8195	7	0.767
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NC_004444	Pseudomonas resinovorans plasmid pCAR1, complete sequence	15836-15865	7	0.767
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NC_021506	Pseudomonas resinovorans NBRC 106553 plasmid pCAR1.3, complete sequence	15836-15865	7	0.767
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NC_011838	Pseudomonas putida plasmid pCAR1.2, complete sequence	15836-15865	7	0.767
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NZ_CP027023	Streptomyces sp. WAC00288 plasmid p1, complete sequence	176836-176865	8	0.733
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NZ_CP027023	Streptomyces sp. WAC00288 plasmid p1, complete sequence	176836-176865	8	0.733
LR216065_2	2.2\|1604358\|30\|LR216065\|CRT	1604358-1604387	30	NZ_CP028970	Aminobacter sp. MSH1 plasmid pUSP2, complete sequence	359832-359861	9	0.7
LR216065_2	2.4\|1604442\|30\|LR216065\|CRT	1604442-1604471	30	NZ_CP028970	Aminobacter sp. MSH1 plasmid pUSP2, complete sequence	359832-359861	9	0.7

1. spacer 2.2|1604358|30|LR216065|CRT matches to NZ_CP051294 (Mesorhizobium sp. NZP2077 plasmid pMSNZP2077A, complete sequence) position: , mismatch: 5, identity: 0.833

gcttgc-tgaggtcgacgcgcttgttgatgc	CRISPR spacer
-catgcatgaggtcgaagcccttgttgatgt	Protospacer
 * *** ********* ** **********.

2. spacer 2.2|1604358|30|LR216065|CRT matches to NZ_CP033363 (Mesorhizobium sp. NZP2077 plasmid pMSNZP2077NSa, complete sequence) position: , mismatch: 5, identity: 0.833

gcttgc-tgaggtcgacgcgcttgttgatgc	CRISPR spacer
-catgcatgaggtcgaagcccttgttgatgt	Protospacer
 * *** ********* ** **********.

3. spacer 2.4|1604442|30|LR216065|CRT matches to NZ_CP051294 (Mesorhizobium sp. NZP2077 plasmid pMSNZP2077A, complete sequence) position: , mismatch: 5, identity: 0.833

gcttgc-tgaggtcgacgcgcttgttgatgc	CRISPR spacer
-catgcatgaggtcgaagcccttgttgatgt	Protospacer
 * *** ********* ** **********.

4. spacer 2.4|1604442|30|LR216065|CRT matches to NZ_CP033363 (Mesorhizobium sp. NZP2077 plasmid pMSNZP2077NSa, complete sequence) position: , mismatch: 5, identity: 0.833

gcttgc-tgaggtcgacgcgcttgttgatgc	CRISPR spacer
-catgcatgaggtcgaagcccttgttgatgt	Protospacer
 * *** ********* ** **********.

5. spacer 2.2|1604358|30|LR216065|CRT matches to NC_007766 (Rhizobium etli CFN 42 plasmid p42f, complete sequence) position: , mismatch: 6, identity: 0.8

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
tcttgctgagttcgacccgcttgttgcagg	Protospacer
 ********* ***** *********  *

6. spacer 2.2|1604358|30|LR216065|CRT matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gcttgc-tgaggtcgacgcgcttgttgatgc	CRISPR spacer
-tgtgcatgaggtcgaagcccttgttgatgt	Protospacer
 . *** ********* ** **********.

7. spacer 2.4|1604442|30|LR216065|CRT matches to NC_007766 (Rhizobium etli CFN 42 plasmid p42f, complete sequence) position: , mismatch: 6, identity: 0.8

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
tcttgctgagttcgacccgcttgttgcagg	Protospacer
 ********* ***** *********  *

8. spacer 2.4|1604442|30|LR216065|CRT matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gcttgc-tgaggtcgacgcgcttgttgatgc	CRISPR spacer
-tgtgcatgaggtcgaagcccttgttgatgt	Protospacer
 . *** ********* ** **********.

9. spacer 2.2|1604358|30|LR216065|CRT matches to NZ_CP016722 (Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11C, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
acttgctgaggtcgacgcccttgtttgact	Protospacer
.***************** ****** .  .

10. spacer 2.2|1604358|30|LR216065|CRT matches to NC_004444 (Pseudomonas resinovorans plasmid pCAR1, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttg---ttgatgc	CRISPR spacer
agttgatgaggtcgacgcgcttgagctgga---	Protospacer
. *** *****************   * **

11. spacer 2.2|1604358|30|LR216065|CRT matches to NC_021506 (Pseudomonas resinovorans NBRC 106553 plasmid pCAR1.3, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttg---ttgatgc	CRISPR spacer
agttgatgaggtcgacgcgcttgagctgga---	Protospacer
. *** *****************   * **

12. spacer 2.2|1604358|30|LR216065|CRT matches to NC_011838 (Pseudomonas putida plasmid pCAR1.2, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttg---ttgatgc	CRISPR spacer
agttgatgaggtcgacgcgcttgagctgga---	Protospacer
. *** *****************   * **

13. spacer 2.4|1604442|30|LR216065|CRT matches to NZ_CP016722 (Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11C, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
acttgctgaggtcgacgcccttgtttgact	Protospacer
.***************** ****** .  .

14. spacer 2.4|1604442|30|LR216065|CRT matches to NC_004444 (Pseudomonas resinovorans plasmid pCAR1, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttg---ttgatgc	CRISPR spacer
agttgatgaggtcgacgcgcttgagctgga---	Protospacer
. *** *****************   * **

15. spacer 2.4|1604442|30|LR216065|CRT matches to NC_021506 (Pseudomonas resinovorans NBRC 106553 plasmid pCAR1.3, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttg---ttgatgc	CRISPR spacer
agttgatgaggtcgacgcgcttgagctgga---	Protospacer
. *** *****************   * **

16. spacer 2.4|1604442|30|LR216065|CRT matches to NC_011838 (Pseudomonas putida plasmid pCAR1.2, complete sequence) position: , mismatch: 7, identity: 0.767

gcttgctgaggtcgacgcgcttg---ttgatgc	CRISPR spacer
agttgatgaggtcgacgcgcttgagctgga---	Protospacer
. *** *****************   * **

17. spacer 2.2|1604358|30|LR216065|CRT matches to NZ_CP027023 (Streptomyces sp. WAC00288 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
gtgccttgaggtcgacgagcttcttgatgt	Protospacer
*. . .*********** **** ******.

18. spacer 2.4|1604442|30|LR216065|CRT matches to NZ_CP027023 (Streptomyces sp. WAC00288 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
gtgccttgaggtcgacgagcttcttgatgt	Protospacer
*. . .*********** **** ******.

19. spacer 2.2|1604358|30|LR216065|CRT matches to NZ_CP028970 (Aminobacter sp. MSH1 plasmid pUSP2, complete sequence) position: , mismatch: 9, identity: 0.7

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
cgatgatgaggtcgacgcccttgttgcctg	Protospacer
   ** ************ ******* .

20. spacer 2.4|1604442|30|LR216065|CRT matches to NZ_CP028970 (Aminobacter sp. MSH1 plasmid pUSP2, complete sequence) position: , mismatch: 9, identity: 0.7

gcttgctgaggtcgacgcgcttgttgatgc	CRISPR spacer
cgatgatgaggtcgacgcccttgttgcctg	Protospacer
   ** ************ ******* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

294 : 33429

Bacillus_phage(18.18%)

transposase,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI38327.1\|294_624_+\|transposase	IS630-Spn1, transposase Orf1	NA	NA	NA	NA
VFI38334.1\|802_1141_+\|transposase	putative IS630-Spn1 transposase	NA	NA	NA	NA
VFI38341.1\|2224_2461_+	recombination regulator RecX	NA	NA	NA	NA
VFI38348.1\|2649_3978_+	adenylosuccinate synthetase	L7Y4J5	Megavirus	2.8e-72	37.1
VFI38355.1\|4178_4646_+	cytidine/deoxycytidylate deaminase	NA	NA	NA	NA
VFI38363.1\|4831_5275_+	deoxyuridine 5'-triphosphate nucleotidohydrolase	Q2WG49	Clostridium_botulinum_D_phage	2.1e-29	47.3
VFI38370.1\|5234_5792_+	phosphoglycerate mutase family protein	NA	NA	NA	NA
VFI38374.1\|5904_7167_+	DNA repair protein	NA	NA	NA	NA
VFI38381.1\|7239_7737_+	carbonic anhydrase	NA	NA	NA	NA
VFI38388.1\|7757_8102_+	repair protein	NA	NA	NA	NA
VFI38397.1\|8098_8635_+\|transposase	IS861 transposase Orf1	NA	NA	NA	NA
VFI38406.1\|8610_9450_+\|transposase	transposase	A0A1B1P773	Bacillus_phage	2.8e-62	50.9
VFI38414.1\|9455_10016_+	repair protein	NA	NA	NA	NA
VFI38421.1\|10160_11129_+	ribose-phosphate pyrophosphokinase	A0A1V0SHF7	Hokovirus	4.0e-44	34.7
VFI38431.1\|11246_11600_+\|transposase	nuclease family transposase	NA	NA	NA	NA
VFI38438.1\|12745_15415_+	DNA polymerase I - 3'-5' exonuclease and polymerase domains	A0A218MKQ4	uncultured_virus	3.5e-58	30.3
VFI38446.1\|15499_15937_+	CoA-binding protein	NA	NA	NA	NA
VFI38454.1\|16166_17177_-	membrane protein	NA	NA	NA	NA
VFI38462.1\|17325_18495_+	aspartate aminotransferase	NA	NA	NA	NA
VFI38470.1\|18491_19262_+	DNA repair protein RecO	NA	NA	NA	NA
VFI38477.1\|19258_20251_+	fatty acid/phospholipid synthesis protein	NA	NA	NA	NA
VFI38484.1\|20256_20490_+	acyl carrier protein	NA	NA	NA	NA
VFI38491.1\|21028_21259_+\|bacteriocin	bacteriocin BlpO	NA	NA	NA	NA
VFI38498.1\|21261_21387_+\|bacteriocin	bacteriocin BlpO	NA	NA	NA	NA
VFI38505.1\|21973_24127_+	competence factor transporting ATP-binding protein/permease ComA	W8CYL7	Bacillus_phage	3.6e-45	28.0
VFI38512.1\|24139_25489_+	competence factor transport protein ComB	NA	NA	NA	NA
VFI38519.1\|25658_26366_+	phosphoribosylaminoimidazole-succinocarboxamide synthetase	A0A1D8KNF0	Synechococcus_phage	1.3e-41	39.2
VFI38526.1\|26567_30293_+	phosphoribosylformylglycinamidine synthase II (FGAM synthetase)	A6N228	Microbacterium_phage	2.1e-37	25.8
VFI38533.1\|30385_31828_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-55	35.1
VFI38540.1\|31864_32887_+	phosphoribosylaminoimidazole synthetase	A0A1D7SE90	Cyanophage	1.2e-64	43.9
VFI38547.1\|32883_33429_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.7e-24	35.0

DBSCAN-SWA_2

85089 : 112798

Streptococcus_phage(66.67%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI38910.1\|85089_85377_+\|bacteriocin	bacteriocin, putative	NA	NA	NA	NA
VFI38917.1\|85428_87537_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
VFI38924.1\|87533_88175_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.3e-23	34.8
VFI38932.1\|88381_89188_+	amino acid ABC transporter periplasmic amino acid-binding protein	NA	NA	NA	NA
VFI38935.1\|89204_89624_+	argininosuccinate synthase, truncation	NA	NA	NA	NA
VFI38943.1\|89912_90776_-	helix-turn-helix domain protein	NA	NA	NA	NA
VFI38950.1\|91241_91580_+	transporter truncation	NA	NA	NA	NA
VFI38957.1\|91557_91929_+	Membrane protein	NA	NA	NA	NA
VFI38964.1\|91936_92149_+	Membrane protein	NA	NA	NA	NA
VFI38971.1\|92522_92648_+	Membrane protein	NA	NA	NA	NA
VFI38978.1\|92628_92874_+\|bacteriocin	putative bacteriocin	NA	NA	NA	NA
VFI38985.1\|93030_94089_+	Uncharacterised protein	NA	NA	NA	NA
VFI38991.1\|94403_95381_+	Leader peptidase	NA	NA	NA	NA
VFI38998.1\|95738_96113_+	Membrane protein	NA	NA	NA	NA
VFI39006.1\|96320_97223_+	Uncharacterised protein	NA	NA	NA	NA
VFI39013.1\|97278_97611_+	Membrane protein	NA	NA	NA	NA
VFI39020.1\|97607_98336_+	Uncharacterised protein	NA	NA	NA	NA
VFI39028.1\|98813_99020_+\|bacteriocin	putative bacteriocin	NA	NA	NA	NA
VFI39035.1\|99860_101690_+	pspA	NA	NA	NA	NA
VFI39042.1\|102094_103216_+\|tRNA	tRNA-specific 2-thiouridylase MnmA	NA	NA	NA	NA
VFI39049.1\|103356_103812_+	mutT/nudix family protein	NA	NA	NA	NA
VFI39056.1\|103821_105735_+\|tRNA	tRNA uridine 5-carboxymethylaminomethyl modification protein GidA	NA	NA	NA	NA
VFI39063.1\|106086_107766_-	metallo-beta-lactamase superfamily protein 1	NA	NA	NA	NA
VFI39070.1\|107767_108001_-	transcriptional regulator	NA	NA	NA	NA
VFI39077.1\|108280_108388_+	Uncharacterised protein	NA	NA	NA	NA
VFI39083.1\|108817_108970_-\|bacteriocin	bacteriocin-type signal sequence domain-containing protein	NA	NA	NA	NA
VFI39090.1\|108971_109157_-	excreted peptide	NA	NA	NA	NA
VFI39097.1\|109334_110018_+	molecular chaperone	NA	NA	NA	NA
VFI39108.1\|110014_110452_+	acetyltransferase	NA	NA	NA	NA
VFI39116.1\|110441_111452_+	O-sialoglycoprotein endopeptidase	NA	NA	NA	NA
VFI39123.1\|111491_111878_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	2.9e-46	73.2
VFI39130.1\|112084_112798_-\|transposase	IS1193, transposase, ISL3 family	A0A1S5SBP9	Streptococcus_phage	3.4e-77	62.0

DBSCAN-SWA_3

147830 : 155391

Streptococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI39364.1\|147830_149780_+	DNA mismatch repair protein hexB	A0A1B2LRQ5	Wolbachia_phage	2.2e-70	32.6
VFI39371.1\|149795_150389_+	holiday junction DNA helicase RuvA	NA	NA	NA	NA
VFI39378.1\|150398_150590_+	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
VFI39386.1\|150586_150775_+	DNA polymerase IV	Q6DMX4	Streptococcus_phage	1.5e-13	90.7
VFI39393.1\|150771_151017_+	Orf5	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
VFI39401.1\|151013_151349_+	ImpB/MucB/SamB family protein	NA	NA	NA	NA
VFI39410.1\|151361_151730_+	YolD-like protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
VFI39418.1\|151716_152016_+	Uncharacterised protein	A0A1B0RX98	Streptococcus_phage	1.8e-48	96.0
VFI39426.1\|152133_153597_-	Ribose import ATP-binding protein rbsA	A0A1B0RXA0	Streptococcus_phage	3.7e-251	97.3
VFI39435.1\|153617_154835_-	macrolide-efflux protein	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
VFI39443.1\|155220_155391_-	CbxX/CfqX family protein	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2

DBSCAN-SWA_4

247826 : 359462

105

Streptococcus_phage(33.33%)

transposase,protease,holin,integrase,tRNA

attL 248606:248639|attR 361721:361754

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI40273.1\|247826_248534_+\|protease	metal-dependent CAAX amino terminal membrane protease	NA	NA	NA	NA
248606:248639	attL	NA	NA	NA	NA
VFI40281.1\|248762_249713_+	dihydropteroate synthase	NA	NA	NA	NA
VFI40290.1\|249714_251037_+	dihydrofolate synthetase	NA	NA	NA	NA
VFI40298.1\|251017_251572_+	GTP cyclohydrolase	E7DN69	Pneumococcus_phage	4.4e-40	44.9
VFI40306.1\|251614_252427_+	bifunctional folate synthesis protein	NA	NA	NA	NA
VFI40314.1\|252471_252789_-	Staphylococcal protein of uncharacterised function (DUF960)	NA	NA	NA	NA
VFI40322.1\|253145_253592_+	50S ribosomal protein L13	NA	NA	NA	NA
VFI40330.1\|253611_254004_+	SSU ribosomal protein S9p (S16e)	NA	NA	NA	NA
VFI40334.1\|254265_254688_-\|integrase	phage integrase family integrase/recombinase	NA	NA	NA	NA
VFI40338.1\|254834_255011_+	Uncharacterised protein	NA	NA	NA	NA
VFI40347.1\|255010_255136_+	filamentation induced by cAMP protein fic	NA	NA	NA	NA
VFI40355.1\|255412_257626_+	glycosyl hydrolase, family 31	NA	NA	NA	NA
VFI40363.1\|257847_258324_-	gluthatione peroxidase	NA	NA	NA	NA
VFI40371.1\|258546_261750_+	hyaluronidase	NA	NA	NA	NA
VFI40381.1\|262303_262519_+\|transposase	truncated IS200 family transposase	A0A1P8BMC0	Lactococcus_phage	3.8e-08	39.5
VFI40389.1\|262893_263523_-	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase	NA	NA	NA	NA
VFI40393.1\|263532_264534_-	carbohydrate kinase, PfkB family	NA	NA	NA	NA
VFI40403.1\|264564_265206_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
VFI40411.1\|265224_266040_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
VFI40420.1\|266311_266746_+	PTS system sugar-specific transporter subunit EII	NA	NA	NA	NA
VFI40428.1\|266757_267948_+	glucuronyl hydrolase	NA	NA	NA	NA
VFI40437.1\|267958_268450_+	N-acetylgalactosamine-specific phosphotransferase EIIB	NA	NA	NA	NA
VFI40439.1\|268464_269244_+	PTS system, N-acetylgalactosamine-specific IIC component	NA	NA	NA	NA
VFI40447.1\|269230_270049_+	PTS system transporter subunit IID	NA	NA	NA	NA
VFI40460.1\|270048_270342_+	preprotein translocase subunit YajC	NA	NA	NA	NA
VFI40467.1\|270363_272265_+	oligohyaluronate lyase	NA	NA	NA	NA
VFI40474.1\|272324_273326_+	sugar binding transcriptional regulator RegR	NA	NA	NA	NA
VFI40483.1\|273435_273771_-	membrane protein	NA	NA	NA	NA
VFI40492.1\|273781_274024_-	Uncharacterised protein	NA	NA	NA	NA
VFI40500.1\|274176_274581_-	membrane protein	NA	NA	NA	NA
VFI40504.1\|274596_274791_-	transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	9.4e-06	42.6
VFI40512.1\|274957_275908_+	S-adenosyl-methyltransferase mraW	NA	NA	NA	NA
VFI40520.1\|275919_276237_+	cell division protein FtsL	NA	NA	NA	NA
VFI40528.1\|276240_278493_+	penicillin-binding protein 2X	NA	NA	NA	NA
VFI40536.1\|278494_279475_+	UDP-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase	NA	NA	NA	NA
VFI40546.1\|280083_282189_+	Group II intron maturase	H6X3M6	Enterobacteria_phage	1.1e-115	37.2
VFI40554.1\|282625_282976_+	group II intron maturase	NA	NA	NA	NA
VFI40562.1\|283042_283525_-	S-ribosylhomocysteinase	NA	NA	NA	NA
VFI40571.1\|283619_285104_-\|protease	ATP-dependent Zn protease	NA	NA	NA	NA
VFI40579.1\|285256_286864_+	glucan 1,6-alpha-glucosidase	NA	NA	NA	NA
VFI40587.1\|287929_289375_+	capsular polysaccharide biosynthesis protein Cps14A	A0A1X9I5X1	Streptococcus_phage	4.0e-133	59.9
VFI40590.1\|289376_290108_+	tyrosine-protein phosphatase CpsB	NA	NA	NA	NA
VFI40598.1\|290116_290809_+	capsular polysaccharide biosynthesis protein Cps14C	A0A1X9I5E1	Streptococcus_phage	1.5e-61	55.5
VFI40606.1\|290818_291502_+	capsular polysaccharide biosynthesis protein Cps14D	A0A1X9I5D6	Streptococcus_phage	2.4e-72	59.9
VFI40614.1\|291517_292885_+	glucosyl-1-phosphate transferase	NA	NA	NA	NA
VFI40622.1\|292888_293338_+	putative glycosyl transferase enhancer	NA	NA	NA	NA
VFI40630.1\|293337_293841_+	ss-1,4-galactosyltransferase	NA	NA	NA	NA
VFI40638.1\|293830_295003_+	polysaccharide polymerase	NA	NA	NA	NA
VFI40646.1\|294999_296019_+	ss-1,3-N-acetylglucosaminyltransferase	NA	NA	NA	NA
VFI40655.1\|296033_296990_+	ss-1,4-galactosyltransferase	A0A1V0SAH6	Catovirus	1.6e-13	39.3
VFI40663.1\|297077_297926_+	capsular polysaccharide synthesis protein	A0A0E3FM02	Synechococcus_phage	7.8e-12	30.7
VFI40671.1\|297918_299382_+	transporter	NA	NA	NA	NA
VFI40679.1\|299365_299698_+	Glycero-transferase	NA	NA	NA	NA
VFI40687.1\|299694_300012_+	Glycero-transferase	NA	NA	NA	NA
VFI40695.1\|300124_303598_+	putative surface anchored protein	NA	NA	NA	NA
VFI40704.1\|303752_304280_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	7.5e-90	96.6
VFI40713.1\|304276_304564_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.6e-22	68.2
VFI40721.1\|304560_305079_-\|transposase	IS1167 transposase	A0A1S5SBP9	Streptococcus_phage	2.3e-75	87.3
VFI40728.1\|305317_307300_+	oligopeptide ABC transporter oligopeptide-binding protein AliA	NA	NA	NA	NA
VFI40737.1\|307600_312904_+	endo-alpha-N-acetylgalactosaminidase	NA	NA	NA	NA
VFI40744.1\|313070_315230_-	penicillin-binding protein 1A	NA	NA	NA	NA
VFI40754.1\|315226_315823_-	recombination protein U	A0A1L2JY30	Aeribacillus_phage	1.5e-17	33.9
VFI40762.1\|315889_316417_+	UPF0398 protein SSU05	NA	NA	NA	NA
VFI40766.1\|316486_316816_+	cell division initiation protein	NA	NA	NA	NA
VFI40776.1\|317301_318459_+	N-6 adenine-specific DNA methylase	NA	NA	NA	NA
VFI40785.1\|318471_319866_+	Holliday junction-specific endonuclease	NA	NA	NA	NA
VFI40787.1\|319941_321366_+\|holin	choline binding protein J	M4QQM4	Ostreococcus_lucimarinus_virus	7.9e-41	29.4
VFI40796.1\|321377_322067_+\|holin	choline binding protein J	NA	NA	NA	NA
VFI40804.1\|322134_323391_-\|transposase	IS1167, transposase	A0A1S5SBP9	Streptococcus_phage	5.4e-227	94.0
VFI40812.1\|323586_324552_+\|holin	choline-binding protein F	NA	NA	NA	NA
VFI40820.1\|324570_325569_+\|holin	choline binding protein J	NA	NA	NA	NA
VFI40828.1\|325686_326919_-	major facilitator superfamily permease	NA	NA	NA	NA
VFI40840.1\|326929_327550_-	lanthionine synthetase C-like protein	NA	NA	NA	NA
VFI40848.1\|328449_328728_+\|holin	choline binding protein C	NA	NA	NA	NA
VFI40856.1\|328902_329781_+	mevalonate kinase	NA	NA	NA	NA
VFI40865.1\|329762_330716_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
VFI40868.1\|330702_331710_+	phosphomevalonate kinase	NA	NA	NA	NA
VFI40877.1\|331693_332704_+	isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2	NA	NA	NA	NA
VFI40885.1\|332780_333479_+	transporter	NA	NA	NA	NA
VFI40893.1\|333475_334471_+	histidine kinase	NA	NA	NA	NA
VFI40903.1\|334484_335117_+	response regulator	NA	NA	NA	NA
VFI40911.1\|335117_335360_+	putative DNA alkylation repair enzyme	NA	NA	NA	NA
VFI40919.1\|336036_336276_+	V8-like Glu-specific endopeptidase	NA	NA	NA	NA
VFI40927.1\|336272_337178_+\|holin	choline binding protein G	NA	NA	NA	NA
VFI40935.1\|337196_337622_+\|holin	choline-binding protein F, point mutation	NA	NA	NA	NA
VFI40943.1\|337739_338219_+\|holin	choline-binding protein F, point mutation	NA	NA	NA	NA
VFI40951.1\|338346_338532_-\|transposase	IS3-Spn1 transposase	A0A2I6AZV9	Macacine_betaherpesvirus	2.7e-10	50.0
VFI40959.1\|338479_338710_-\|transposase	IS3-Spn1 transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.4e-08	57.4
VFI40967.1\|338771_339044_-\|transposase	IS3-Spn1 transposase	A0A1B1P773	Bacillus_phage	5.0e-13	48.1
VFI40975.1\|339269_339539_-\|transposase	degenerate transposase (Orf1)	NA	NA	NA	NA
VFI40983.1\|339690_341460_+	PTS system mannitol-specific transporter subunit EIIBC	NA	NA	NA	NA
VFI40991.1\|341483_343439_+	putative transcriptional regulator MtlR	NA	NA	NA	NA
VFI40999.1\|343440_343878_+	mannitol-specific phosphotransferase EIIA	NA	NA	NA	NA
VFI41007.1\|343939_345076_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
VFI41016.1\|345919_347203_+	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	NA	NA	NA	NA
VFI41024.1\|347250_349617_-	recombinase D	A0A0K2FLP8	Brevibacillus_phage	3.7e-59	27.3
VFI41032.1\|349850_350465_-	signal peptidase I	NA	NA	NA	NA
VFI41040.1\|350476_351349_-	ribonuclease HIII	NA	NA	NA	NA
VFI41049.1\|351435_351738_+\|tRNA	seryl-tRNA synthetase	NA	NA	NA	NA
VFI41052.1\|351734_352283_+	CvpA family protein	NA	NA	NA	NA
VFI41060.1\|352386_354723_+	mismatch repair ATPase (MutS family)	Q94M10	Lactobacillus_phage	1.3e-21	55.1
VFI41068.1\|355065_356388_+	Na+/alanine symporter	NA	NA	NA	NA
VFI41076.1\|356605_357154_+	macrophage infectivity potentiator protein	NA	NA	NA	NA
VFI41078.1\|357263_358163_+	exfoliative toxin	NA	NA	NA	NA
VFI41081.1\|358187_359462_-\|tRNA	seryl-tRNA synthetase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.7e-91	48.5
361721:361754	attR	NA	NA	NA	NA

DBSCAN-SWA_5

375087 : 433122

Planktothrix_phage(18.18%)

transposase,integrase,tRNA

attL 430100:430159|attR 433785:433890

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI41256.1\|375087_376530_-\|tRNA	glutamyl tRNA-Gln amidotransferase chain B	NA	NA	NA	NA
VFI41264.1\|376529_377996_-\|tRNA	glutamyl-tRNA(Gln) amidotransferase, A subunit	NA	NA	NA	NA
VFI41272.1\|377995_378298_-\|tRNA	aspartyl/glutamyl-tRNA amidotransferase subunit C	NA	NA	NA	NA
VFI41280.1\|378510_380055_+	regulator of gtfB	A0A1B0RXH7	Streptococcus_phage	8.3e-36	28.5
VFI41284.1\|380309_380507_+	glycosyl transferase, family 8	NA	NA	NA	NA
VFI41292.1\|381081_381567_-\|transposase	IS1202 transposase	NA	NA	NA	NA
VFI41295.1\|381771_381960_+	LSU ribosomal protein L28p	NA	NA	NA	NA
VFI41302.1\|382116_382482_+	alkaline shock protein	NA	NA	NA	NA
VFI41307.1\|382484_384152_+	kinase	NA	NA	NA	NA
VFI41315.1\|384352_386053_+	acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.2e-67	32.2
VFI41319.1\|386045_386522_+	acetolactate synthase 3 regulatory subunit	NA	NA	NA	NA
VFI41329.1\|386587_387610_+	ketol-acid reductoisomerase	NA	NA	NA	NA
VFI41337.1\|387716_387953_+	Uncharacterised protein	NA	NA	NA	NA
VFI41350.1\|388190_388547_+	ketol-acid reductoisomerase	NA	NA	NA	NA
VFI41356.1\|388596_389847_+	threonine dehydratase	NA	NA	NA	NA
VFI41364.1\|390730_390946_+	Uncharacterised protein	NA	NA	NA	NA
VFI41372.1\|391054_391795_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-27	37.9
VFI41380.1\|391794_393360_-	ABC transporter-amino acid transport; amino acid-binding protein/permease protein	NA	NA	NA	NA
VFI41388.1\|393497_395387_+	Predicted membrane protein (DUF2207)	NA	NA	NA	NA
VFI41397.1\|395765_396236_-\|transposase	degenerate transposase	A0A1B1P7S0	Bacillus_phage	5.1e-05	39.5
VFI41405.1\|396433_396556_-\|transposase	degenerate transposase	NA	NA	NA	NA
VFI41414.1\|396811_397657_+	undecaprenol kinase	NA	NA	NA	NA
VFI41422.1\|398040_399102_-	DNA polymerase IV	NA	NA	NA	NA
VFI41428.1\|399449_401774_+	pyruvate formate-lyase	A0A2P0VNR5	Tetraselmis_virus	7.9e-115	32.9
VFI41436.1\|402141_402360_-	Uncharacterised protein	NA	NA	NA	NA
VFI41440.1\|402686_402971_-	Uncharacterised protein	NA	NA	NA	NA
VFI41448.1\|403582_403753_-\|transposase	ISSpo8 transposase	NA	NA	NA	NA
VFI41456.1\|404313_404772_+	PTS system lactose-specific transporter subunit IIBC	NA	NA	NA	NA
VFI41464.1\|404897_406337_-	potassium uptake protein	NA	NA	NA	NA
VFI41472.1\|406340_407690_-	potassium uptake protein	NA	NA	NA	NA
VFI41481.1\|407877_408726_+	Molybdate/tungstate binding protein	NA	NA	NA	NA
VFI41489.1\|408740_409289_+	protein YdcD	NA	NA	NA	NA
VFI41497.1\|409295_409553_+	N-ethylammeline chlorohydrolase	NA	NA	NA	NA
VFI41507.1\|409654_411337_+	cobalt ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-19	34.9
VFI41516.1\|411321_412152_+	ABC transporter permease	NA	NA	NA	NA
VFI41523.1\|412344_412848_+	RNA methyltransferase	NA	NA	NA	NA
VFI41531.1\|413300_413864_+	riboflavin transporter	NA	NA	NA	NA
VFI41540.1\|413853_414504_+	phosphatase	NA	NA	NA	NA
VFI41549.1\|414531_414921_+	putative histone acetyltransferase	NA	NA	NA	NA
VFI41557.1\|414925_415375_+	sortase-like acyltransferase	NA	NA	NA	NA
VFI41565.1\|415502_416090_+	DNA-dependent RNA Polymerase, delta subunit (RNAP delta factor)	NA	NA	NA	NA
VFI41573.1\|416479_418087_+	CTP synthetase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.9e-142	47.0
VFI41581.1\|418645_420277_-	sodium-dependent phosphate transporter	NA	NA	NA	NA
VFI41589.1\|420565_425506_+	endo-beta-N-acetylglucosaminidase	NA	NA	NA	NA
VFI41597.1\|425595_426792_+	phosphoglycerate kinase	NA	NA	NA	NA
VFI41605.1\|426927_427455_+	membrane protein	NA	NA	NA	NA
VFI41613.1\|427531_427888_+	transcriptional repressor of the glutamine synthetase gene	NA	NA	NA	NA
VFI41621.1\|427924_429271_+	glutamate-ammonia ligase	NA	NA	NA	NA
VFI41629.1\|429444_429594_+	Uncharacterised protein	NA	NA	NA	NA
VFI41637.1\|430060_430765_+	type I restriction enzyme	A0A1V0SLK8	Klosneuvirus	4.5e-13	30.1
430100:430159	attL	NA	NA	NA	NA
VFI41646.1\|430712_431255_-	type I restriction modification DNA specificity domain-containing protein	NA	NA	NA	NA
VFI41656.1\|431325_431817_-\|integrase	integrase/recombinase, phage integrase family	A0A0H4TI16	Erysipelothrix_phage	2.8e-14	31.1
VFI41664.1\|431813_432314_-	putative type I restriction-modification system S protein	E3T4D5	Cafeteria_roenbergensis_virus	8.1e-09	35.9
VFI41672.1\|432324_433122_-\|integrase	integrase/recombinase, phage integrase family	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
433785:433890	attR	NA	NA	NA	NA

DBSCAN-SWA_6

453108 : 484085

Bacillus_phage(40.0%)

transposase,bacteriocin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI41831.1\|453108_453264_-\|bacteriocin	peptide pheromone BlpC (bacteriocin-like peptide)	NA	NA	NA	NA
VFI41839.1\|453320_454682_-	BlpC ABC transporter	NA	NA	NA	NA
VFI41848.1\|454692_456846_-	competence factor transporting ATP-binding protein/permease ComA	W8CYL7	Bacillus_phage	8.2e-42	27.6
VFI41856.1\|457126_457357_+\|bacteriocin	bacteriocin-like peptide N BlpN	NA	NA	NA	NA
VFI41865.1\|457775_457940_+	putative immunity protein	NA	NA	NA	NA
VFI41873.1\|457936_458341_+	immunity protein BlpL	NA	NA	NA	NA
VFI41881.1\|458538_458727_+	mobile genetic element	NA	NA	NA	NA
VFI41886.1\|458954_459344_+\|transposase	transposase	NA	NA	NA	NA
VFI41894.1\|459545_459800_+	BlpM	NA	NA	NA	NA
VFI41898.1\|459815_460019_+	blpN protein	NA	NA	NA	NA
VFI41906.1\|460274_460412_+\|bacteriocin	bacteriocin BlpO	NA	NA	NA	NA
VFI41914.1\|461420_461804_+	putative immunity protein BlpX	NA	NA	NA	NA
VFI41924.1\|461855_462545_+\|protease	metal-dependent CAAX amino terminal membrane protease	NA	NA	NA	NA
VFI41932.1\|462586_462820_+	immunity protein BlpZ	NA	NA	NA	NA
VFI41941.1\|462970_463582_+\|protease	CAAX amino terminal protease family protein	NA	NA	NA	NA
VFI41950.1\|463742_464537_+	aminoglycoside phosphotransferase	NA	NA	NA	NA
VFI41958.1\|464533_465169_+\|tRNA	tRNA (guanine-N(7)-)-methyltransferase	NA	NA	NA	NA
VFI41966.1\|465247_465775_+	SP14.3 protein	NA	NA	NA	NA
VFI41974.1\|465830_466955_+	transcription elongation factor NusA	NA	NA	NA	NA
VFI41982.1\|466976_467270_+	cytosolic protein YlxR	NA	NA	NA	NA
VFI41990.1\|467262_467562_+	L7A family ribosomal protein	NA	NA	NA	NA
VFI41998.1\|467578_470371_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.3e-19	22.9
VFI42003.1\|470621_470972_+	ribosome-binding factor A	NA	NA	NA	NA
VFI42011.1\|471250_472030_+	ABC transporter ATPase	NA	NA	NA	NA
VFI42019.1\|472031_472214_+	Uncharacterised protein	NA	NA	NA	NA
VFI42029.1\|472210_472351_+	Uncharacterised protein	NA	NA	NA	NA
VFI42037.1\|472664_472898_+	Domain of uncharacterised function (DUF1858)	NA	NA	NA	NA
VFI42045.1\|472897_474232_+	hemerythrin HHE cation binding domain subfamily	NA	NA	NA	NA
VFI42053.1\|474241_474496_+	aldose 1-epimerase	NA	NA	NA	NA
VFI42061.1\|474591_474987_+	Helicase	NA	NA	NA	NA
VFI42065.1\|475398_475794_+	conserved protein/domain typically associated with flavoprotein oxygenase, Dim6/ntab family	NA	NA	NA	NA
VFI42073.1\|475833_476394_+	acetyltransferase, gnat family	NA	NA	NA	NA
VFI42082.1\|476393_476972_+	shikimate kinase	NA	NA	NA	NA
VFI42090.1\|476964_479616_+\|tRNA	valyl-tRNA synthetase	A0A1V0S951	Catovirus	3.5e-151	40.9
VFI42098.1\|479696_479861_+	type II DNA modification methyltransferase, truncation	NA	NA	NA	NA
VFI42106.1\|479911_481516_+	Uncharacterized conserved protein	NA	NA	NA	NA
VFI42114.1\|481895_482699_+	Fic protein family	NA	NA	NA	NA
VFI42122.1\|482814_483303_-\|transposase	IS3-Spn1 transposase, truncation	A0A2I6AZV9	Macacine_betaherpesvirus	9.6e-39	50.9
VFI42131.1\|483278_483647_-\|transposase	degenerate transposase (Orf2)	A0A1B1P773	Bacillus_phage	8.9e-13	53.6
VFI42140.1\|483872_484085_-\|transposase	transposase orfA, ISSmu1	NA	NA	NA	NA

DBSCAN-SWA_7

548755 : 598980

Staphylococcus_prophage(25.0%)

bacteriocin,transposase,protease,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI42621.1\|548755_555187_+\|protease	serine protease	NA	NA	NA	NA
VFI42630.1\|555813_556290_+	PTS system transporter subunit IIA	NA	NA	NA	NA
VFI42638.1\|556327_556633_+	PTS system IIB component (galactitol/fructose specific)	NA	NA	NA	NA
VFI42646.1\|556680_558156_+	PTS system galactitol-specific family transporter subunit IIC	NA	NA	NA	NA
VFI42654.1\|558422_558767_+	beta-galactosidase	NA	NA	NA	NA
VFI42662.1\|558857_565124_+	beta-galactosidase	NA	NA	NA	NA
VFI42670.1\|565371_565995_-\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	2.3e-05	40.0
VFI42672.1\|565982_566228_-\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	7.7e-13	44.9
VFI42680.1\|566439_566799_-	integral membrane protein	NA	NA	NA	NA
VFI42683.1\|566890_567400_+	radical SAM family protein	NA	NA	NA	NA
VFI42691.1\|567400_567805_+	putative Fe-S oxidoreductase	A0A2H4PQV5	Staphylococcus_phage	5.9e-34	51.1
VFI42699.1\|567830_568388_+	SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	2.4e-33	40.9
VFI42707.1\|568380_568530_+	Uncharacterised protein	NA	NA	NA	NA
VFI42715.1\|568504_569929_+	sodium hydrogen exchange transporter	NA	NA	NA	NA
VFI42723.1\|570107_570968_+	ribonuclease BN	NA	NA	NA	NA
VFI42731.1\|571178_571889_+	cytochrome c-type biogenesis protein	NA	NA	NA	NA
VFI42739.1\|571908_572475_+	thioredoxin	NA	NA	NA	NA
VFI42748.1\|572485_573598_+	peptide methionine sulfoxide reductase	NA	NA	NA	NA
VFI42754.1\|573955_574693_+	DNA-binding response regulator	NA	NA	NA	NA
VFI42762.1\|574689_576381_+	histidine kinase	Q9EYF3	Enterobacteria_phage	9.4e-25	32.7
VFI42770.1\|576496_577060_+	UPF0340 protein SSU05	NA	NA	NA	NA
VFI42779.1\|577081_583024_+\|protease	zinc metalloprotease ZmpB	NA	NA	NA	NA
VFI42787.1\|583084_584806_+	chorismate binding enzyme para-aminobenzoate synthetase	A0A0B5J984	Pandoravirus	1.2e-38	29.9
VFI42795.1\|584806_585424_+	putative alpha/beta superfamily hydrolase	NA	NA	NA	NA
VFI42805.1\|585473_586472_+\|holin	choline binding protein	NA	NA	NA	NA
VFI42815.1\|586598_587558_+	glucokinase	NA	NA	NA	NA
VFI42823.1\|587654_588494_+	thymidylate synthase	U5J9N5	Bacillus_phage	3.6e-86	54.6
VFI42832.1\|588541_588712_-	putative uncharacterized protein ORF 3	NA	NA	NA	NA
VFI42840.1\|588832_589717_+\|tRNA	tRNA delta(2)-isopentenylpyrophosphate transferase	NA	NA	NA	NA
VFI42850.1\|589709_590948_+	GTP-binding protein HflX	NA	NA	NA	NA
VFI42859.1\|590940_591564_+	cystathionine beta-lyase	NA	NA	NA	NA
VFI42863.1\|591578_592508_+	hydrolase	NA	NA	NA	NA
VFI42871.1\|592528_593284_+	dehydrogenase	NA	NA	NA	NA
VFI42879.1\|593337_594306_-	transcriptional regulator	A0A2H4J8I9	uncultured_Caudovirales_phage	1.5e-06	28.9
VFI42887.1\|594309_594579_+	hypothetical cytosolic protein	NA	NA	NA	NA
VFI42896.1\|594578_594959_+	rhodanese family protein	NA	NA	NA	NA
VFI42905.1\|595077_595275_+	Uncharacterised protein	NA	NA	NA	NA
VFI42913.1\|595314_596040_-	ribosomal small subunit pseudouridine synthase A	NA	NA	NA	NA
VFI42921.1\|596201_598043_+	GTP-binding protein TypA	NA	NA	NA	NA
VFI42933.1\|598062_598317_+	membrane protein	NA	NA	NA	NA
VFI42941.1\|598632_598980_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_8

684240 : 788019

108

Streptococcus_phage(15.62%)

transposase,integrase,tRNA,protease

attL 778098:778120|attR 780503:780525

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI43711.1\|684240_686238_+\|tRNA	methionyl-tRNA synthetase	A0A1V0SEZ7	Hokovirus	1.8e-83	31.2
VFI43722.1\|686523_686844_+	PadR family transcriptional regulator	NA	NA	NA	NA
VFI43730.1\|686847_687663_+	membrane protein	NA	NA	NA	NA
VFI43738.1\|687737_688664_+	aldo/keto reductase family oxidoreductase	NA	NA	NA	NA
VFI43747.1\|688759_688996_+\|tRNA	methionine--tRNA ligase	NA	NA	NA	NA
VFI43755.1\|688988_689687_+	short chain dehydrogenase	A0A0K0KVL6	Prochlorococcus_phage	6.2e-07	30.9
VFI43764.1\|689697_690198_+	NTP pyrophosphohydrolase including oxidative damage repair enzymes	NA	NA	NA	NA
VFI43768.1\|690175_691045_+	PEP-utilizing enzyme family protein	NA	NA	NA	NA
VFI43776.1\|691019_691460_+	acetyltransferase	NA	NA	NA	NA
VFI43786.1\|691582_694129_+	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	1.3e-73	27.1
VFI43794.1\|694237_694912_+	DNA-binding response regulator CiaR	W8CYM9	Bacillus_phage	3.1e-27	33.6
VFI43802.1\|694901_696236_+	histidine kinase	Q8QNA2	Ectocarpus_siliculosus_virus	1.2e-06	34.0
VFI43808.1\|696269_696557_-	membrane protein	NA	NA	NA	NA
VFI43817.1\|696696_697626_+	U32 family peptidase	NA	NA	NA	NA
VFI43827.1\|697825_700276_+	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	2.6e-201	47.7
VFI43835.1\|700312_701536_+	RodA	NA	NA	NA	NA
VFI43844.1\|701546_702101_+	4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein	A0A0N7KVR4	Yellowstone_lake_phycodnavirus	6.4e-07	27.2
VFI43852.1\|702176_702749_+	phosphatase	NA	NA	NA	NA
VFI43860.1\|702763_704710_+	DNA gyrase subunit B	G3M9Z3	Bacillus_virus	3.2e-146	45.6
VFI43868.1\|704791_706519_+	septation ring formation regulator EzrA	NA	NA	NA	NA
VFI43876.1\|707825_708125_-	Domain of uncharacterised function (DUF1827)	NA	NA	NA	NA
VFI43884.1\|708289_708754_-	mutT/nudix family protein	NA	NA	NA	NA
VFI43892.1\|708821_709220_+\|transposase	IS630-Spn1, transposase Orf1	NA	NA	NA	NA
VFI43899.1\|709328_709667_+\|transposase	IS630-Spn1, transposase Orf2	NA	NA	NA	NA
VFI43907.1\|709873_712132_-\|protease	ATP-dependent Clp protease, ATP-binding subunit	K4FB40	Cronobacter_phage	4.6e-128	40.4
VFI43915.1\|712360_712591_-	Protein of uncharacterised function (DUF1797)	NA	NA	NA	NA
VFI43924.1\|712780_713464_+	amino acid ABC transporter permease	NA	NA	NA	NA
VFI43934.1\|713463_714198_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	43.1
VFI43942.1\|714351_715209_+	FolD bifunctional protein; includes: methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	6.8e-40	41.5
VFI43950.1\|715346_716168_+	ABC-type phosphate transport system, ATPase component	NA	NA	NA	NA
VFI43959.1\|716182_717055_+	carbohydrate kinase	NA	NA	NA	NA
VFI43967.1\|717336_718020_+	ribose-5-phosphate isomerase A	NA	NA	NA	NA
VFI43975.1\|718033_719245_+	phosphopentomutase	NA	NA	NA	NA
VFI43984.1\|719246_719420_+	phosphopentomutase	NA	NA	NA	NA
VFI43992.1\|719534_719804_+	phosphopentomutase	NA	NA	NA	NA
VFI44000.1\|719803_720613_+	purine nucleoside phosphorylase	NA	NA	NA	NA
VFI44008.1\|721076_721484_+	topology modulation protein	NA	NA	NA	NA
VFI44017.1\|721493_722069_+	thiol-activated cytolysin	NA	NA	NA	NA
VFI44025.1\|722093_722606_+	pneumolysin	NA	NA	NA	NA
VFI44030.1\|723263_723974_+	purine nucleoside phosphorylase	NA	NA	NA	NA
VFI44038.1\|723996_724521_-	topology modulation protein	A0A097BYE2	Leuconostoc_phage	1.2e-26	40.6
VFI44046.1\|724573_724810_-	putative 30S ribosomal protein S20	NA	NA	NA	NA
VFI44054.1\|724877_725798_-	pantothenate kinase	NA	NA	NA	NA
VFI44063.1\|725987_726392_+	membrane protein (pseudogene)	NA	NA	NA	NA
VFI44071.1\|726607_727189_+	16S RNA G1207 methylase RsmC	NA	NA	NA	NA
VFI44079.1\|727185_728463_+	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	2.8e-114	52.0
VFI44088.1\|728480_729143_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
VFI44094.1\|729129_729519_+	cytidine deaminase	NA	NA	NA	NA
VFI44102.1\|729608_730661_+	lipoprotein	NA	NA	NA	NA
VFI44110.1\|730804_732340_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-19	32.5
VFI44118.1\|732332_733391_+	sugar ABC transporter permease	NA	NA	NA	NA
VFI44130.1\|733393_734350_+	ABC transporter, membrane-spanning permease	NA	NA	NA	NA
VFI44138.1\|734434_734647_+\|transposase	transposase orfA, ISSmu1	NA	NA	NA	NA
VFI44146.1\|734782_734950_+\|transposase	IS3-Spn1 transposase	NA	NA	NA	NA
VFI44154.1\|734949_735222_+\|transposase	IS3-Spn1 transposase	A0A1B1P773	Bacillus_phage	4.5e-14	50.6
VFI44163.1\|735283_735772_+\|transposase	IS3-Spn1 transposase, truncation	A0A2I6AZV9	Macacine_betaherpesvirus	2.5e-39	51.6
VFI44168.1\|735814_736456_-	putative glycerol-3-phosphate acyltransferase PlsY	NA	NA	NA	NA
VFI44176.1\|736591_738535_+	topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	7.0e-125	43.0
VFI44181.1\|738534_738642_+	N-6 DNA methylase	NA	NA	NA	NA
VFI44189.1\|738990_741426_+	topoisomerase IV subunit A, ParC	G3M9Z5	Bacillus_virus	1.9e-95	31.3
VFI44197.1\|741557_742580_+	branched-chain amino acid aminotransferase	NA	NA	NA	NA
VFI44205.1\|742635_743340_+	extracellular oligopeptide-binding protein	NA	NA	NA	NA
VFI44217.1\|743404_744094_+	permease	NA	NA	NA	NA
VFI44225.1\|744090_745014_+	permease	NA	NA	NA	NA
VFI44233.1\|745028_745673_+	pyroglutamyl-peptidase I	NA	NA	NA	NA
VFI44242.1\|745840_746071_+	branched-chain amino acid aminotransferase	NA	NA	NA	NA
VFI44250.1\|746443_747646_+	30S ribosomal protein S1	NA	NA	NA	NA
VFI44259.1\|747731_748259_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.3e-89	96.0
VFI44268.1\|748255_748543_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.1e-23	71.8
VFI44276.1\|748539_749058_-\|transposase	IS1167 transposase	A0A1S5SBP9	Streptococcus_phage	3.2e-77	88.5
VFI44284.1\|749249_749747_+	GAF domain-containing protein	NA	NA	NA	NA
VFI44292.1\|749746_751402_+	DNA polymerase III subunits gamma and tau	A0A1U9WR94	Streptococcus_virus	1.1e-46	41.9
VFI44300.1\|751429_751624_+	membrane protein	NA	NA	NA	NA
VFI44308.1\|751773_752544_+	FeS assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	2.5e-09	28.5
VFI44316.1\|752571_753834_+	FeS assembly protein SufD	NA	NA	NA	NA
VFI44324.1\|753844_755071_+	class-V aminotransferase	Q2XUY6	environmental_halophage	1.5e-104	44.8
VFI44333.1\|755057_755498_+	nifU family protein	A0A2P1CJL8	Mycobacterium_phage	1.6e-13	39.0
VFI44341.1\|755551_756964_+	Iron-sulfur cluster assembly protein SufB	NA	NA	NA	NA
VFI44349.1\|757194_758436_-	D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 3	B6DZZ7	Stx2-converting_phage	1.1e-17	25.5
VFI44357.1\|758538_759648_+	putative permease	NA	NA	NA	NA
VFI44366.1\|760772_761549_-	Domain of uncharacterised function DUF1828	NA	NA	NA	NA
VFI44371.1\|761575_762046_-	Uncharacterised protein	NA	NA	NA	NA
VFI44379.1\|762100_762565_-	phage super infection exclusion	A0A060AN66	Enterococcus_phage	3.5e-06	41.0
VFI44387.1\|763169_763910_+	transcriptional repressor of fructose operon	NA	NA	NA	NA
VFI44395.1\|763906_764818_+	fructose-1-phosphate kinase	NA	NA	NA	NA
VFI44403.1\|764814_766767_+	PTS system, fructose specific IIBC component	NA	NA	NA	NA
VFI44413.1\|766852_769156_+	DNA translocase, cell division protein	S5VNE3	Mycobacterium_phage	1.0e-85	49.9
VFI44421.1\|769200_769635_-	TBC1 domain family member 8B	NA	NA	NA	NA
VFI44430.1\|769773_770916_+	class-V aminotransferase	NA	NA	NA	NA
VFI44438.1\|770924_772139_+	thiamine biosynthesis ATP pyrophosphatase	NA	NA	NA	NA
VFI44446.1\|772273_773098_+	Esterase	NA	NA	NA	NA
VFI44457.1\|773119_773455_+	esterase superfamily protein	NA	NA	NA	NA
VFI44465.1\|773451_773859_+	esterase	NA	NA	NA	NA
VFI44473.1\|773871_775038_+	carbamoylphosphate synthase large subunit	NA	NA	NA	NA
VFI44481.1\|775545_777039_+	type I restriction modification enzyme methylase subunit	A0A2H4UVB0	Bodo_saltans_virus	3.0e-27	31.8
VFI44491.1\|777051_777594_+	type I restriction-modification system subunit S	NA	NA	NA	NA
VFI44500.1\|777590_778709_+	type I restriction-modification system subunit S	NA	NA	NA	NA
778098:778120	attL	NA	NA	NA	NA
VFI44508.1\|778768_779005_+	toxin-antitoxin system, antitoxin component,AbrB family	NA	NA	NA	NA
VFI44516.1\|779001_779415_+	prophage maintenance system killer protein	NA	NA	NA	NA
VFI44524.1\|779532_780498_+\|integrase	integrase/recombinase, phage integrase family protein	A0A2H4JAA2	uncultured_Caudovirales_phage	1.8e-33	29.6
VFI44532.1\|780520_781006_+	type I restriction-modification system subunit S	NA	NA	NA	NA
780503:780525	attR	NA	NA	NA	NA
VFI44541.1\|781132_784483_+	type I restriction-modification system R subunit	A0A2H4P9W3	Gordonia_phage	1.4e-11	24.8
VFI44550.1\|784882_786229_-\|transposase	IS1380-Spn1 transposase	A0A1X9I6F6	Streptococcus_phage	2.2e-77	39.8
VFI44558.1\|786362_786485_+	Uncharacterised protein	NA	NA	NA	NA
VFI44567.1\|786462_786663_+	chlorohydrolase	NA	NA	NA	NA
VFI44575.1\|786864_787140_-\|transposase	degenerate transposase	NA	NA	NA	NA
VFI44584.1\|787195_787339_+	Uncharacterised protein	NA	NA	NA	NA
VFI44593.1\|787431_788019_+\|protease	Tn5253 CAAX amino terminal protease family	NA	NA	NA	NA

DBSCAN-SWA_9

806127 : 903068

104

Streptococcus_phage(40.0%)

transposase,protease,holin,integrase,tRNA

attL 850383:850398|attR 901196:901211

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI44731.1\|806127_806655_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	8.3e-89	95.4
VFI44738.1\|806651_806939_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	9.6e-23	69.4
VFI44745.1\|806935_807454_-\|transposase	IS1167 transposase	A0A1S5SBP9	Streptococcus_phage	7.2e-77	89.2
VFI44752.1\|808133_808604_-	arginine repressor	NA	NA	NA	NA
VFI44760.1\|808620_810894_-	x-prolyl-dipeptidyl aminopeptidase	NA	NA	NA	NA
VFI44767.1\|811240_814342_+	DNA-polymerase III alpha-chain	A0A291AWR1	Streptomyces_phage	8.9e-114	32.8
VFI44774.1\|814424_815432_+	6-phosphofructokinase	NA	NA	NA	NA
VFI44781.1\|815490_816996_+	pyruvate kinase	NA	NA	NA	NA
VFI44788.1\|818813_819686_+	lipoprotein, putative	NA	NA	NA	NA
VFI44799.1\|819792_820176_-\|transposase	transposase-like protein, IS1381 ISSpn7	NA	NA	NA	NA
VFI44806.1\|820318_820630_+	Uncharacterised protein	NA	NA	NA	NA
VFI44814.1\|820633_821350_+	alpha/beta hydrolase related protein	NA	NA	NA	NA
VFI44821.1\|821479_822295_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
VFI44828.1\|822291_823197_-	membrnae protein	NA	NA	NA	NA
VFI44835.1\|823197_823329_-	putative type II restriction endonuclease DpnI	NA	NA	NA	NA
VFI44842.1\|823586_824906_+	capsular polysaccharide biosynthesis protein	NA	NA	NA	NA
VFI44850.1\|825007_827137_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
VFI44858.1\|827123_827573_+	SprT family protein	NA	NA	NA	NA
VFI44865.1\|827630_827903_+	PspC domain-containing protein	NA	NA	NA	NA
VFI44872.1\|828256_828448_-	Uncharacterised protein	NA	NA	NA	NA
VFI44879.1\|828750_828861_+	Uncharacterised protein	NA	NA	NA	NA
VFI44887.1\|828875_829634_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-27	36.3
VFI44895.1\|829635_831624_+	ABC transporter, membrane-spanning protein	NA	NA	NA	NA
VFI44903.1\|831665_832256_-	integral membrane protein	NA	NA	NA	NA
VFI44910.1\|832335_833211_-\|transposase	IS1239 transposase	H7BWC8	unidentified_phage	4.0e-27	31.3
VFI44917.1\|833917_835393_+	ornithine decarboxylase family protein	NA	NA	NA	NA
VFI44925.1\|835358_836075_-	pilin gene inverting-like protein	NA	NA	NA	NA
VFI44932.1\|836329_837190_+	spermidine synthase	NA	NA	NA	NA
VFI44939.1\|837186_838446_+	dehydrogenase family protein, saccharopine dehydrogenase	NA	NA	NA	NA
VFI44946.1\|838445_839573_+	LysA-like decarboxylase, diaminopimelate decarboxylase putative	NA	NA	NA	NA
VFI44954.1\|839569_840655_+	agmatine deiminase	M1HES8	Acanthocystis_turfacea_Chlorella_virus	5.9e-89	47.2
VFI44961.1\|840664_841540_+	carbon-nitrogen hydrolase family protein	M1H5W0	Paramecium_bursaria_Chlorella_virus	1.1e-77	50.0
VFI44968.1\|841720_842530_-	Cof family protein	NA	NA	NA	NA
VFI44976.1\|842801_843023_+	Uncharacterised protein	NA	NA	NA	NA
VFI44983.1\|843076_843748_+\|protease	caax amino protease family protein	NA	NA	NA	NA
VFI44991.1\|843989_844898_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.1e-06	27.7
VFI44998.1\|844894_845356_+	lipoprotein signal peptidase, signal peptidase type II	NA	NA	NA	NA
VFI45006.1\|845345_846233_+	23S rluA family pseudouridine synthase	NA	NA	NA	NA
VFI45017.1\|846235_848119_+\|holin	choline binding protein E CbpE	Q332B9	Clostridium_botulinum_C_phage	1.2e-09	22.9
VFI45024.1\|848219_849329_+	gamma-glutamyl kinase	A0A1X9I5D0	Streptococcus_phage	8.4e-115	58.4
VFI45032.1\|849338_850601_+	gamma-glutamyl phosphate reductase	A0A1X9I5D4	Streptococcus_phage	2.5e-139	64.5
850383:850398	attL	NA	NA	NA	NA
VFI45039.1\|850604_851402_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.2e-59	50.9
VFI45042.1\|851621_852260_+	thymidylate kinase	M1PSC7	Streptococcus_phage	6.4e-75	67.6
VFI45049.1\|852256_853147_+	DNA polymerase III, delta' subunit	M1NSC1	Streptococcus_phage	4.9e-73	51.7
VFI45057.1\|853186_853504_+	DNA replication intiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
VFI45064.1\|853506_854376_+	tetrapyrrole methylase	M1PLC5	Streptococcus_phage	2.7e-116	76.1
VFI45072.1\|854602_855121_+	DUF1706 domain-containing protein	NA	NA	NA	NA
VFI45079.1\|855229_855367_+	phage protein, point mutation	NA	NA	NA	NA
VFI45087.1\|855373_855808_+	phage protein	A0A2P0VK56	Streptococcus_phage	4.6e-08	40.0
VFI45094.1\|855865_856255_-	fusion of IS1381 orf A and B	NA	NA	NA	NA
VFI45096.1\|856271_856673_-\|transposase	transposase-like protein, IS1381 ISSpn7	NA	NA	NA	NA
VFI45103.1\|857079_858450_+\|tRNA	tRNA (uracil-5-)-methyltransferase Gid	NA	NA	NA	NA
VFI45110.1\|858533_859271_+	uridylate kinase	NA	NA	NA	NA
VFI45113.1\|859279_859837_+	ribosome-recycling factor	NA	NA	NA	NA
VFI45120.1\|859896_860751_+	s1 RNA binding domain protein	NA	NA	NA	NA
VFI45127.1\|860759_860975_+	serine-type D-Ala-D-Ala carboxypeptidase	NA	NA	NA	NA
VFI45135.1\|861060_862029_+	PhoH family protein	W8D063	Erwinia_phage	5.9e-48	47.9
VFI45143.1\|862097_862499_+\|transposase	transposase	NA	NA	NA	NA
VFI45147.1\|862510_862888_+\|transposase	transposase (IS4 family)	NA	NA	NA	NA
VFI45154.1\|863070_863571_+	acetyltransferase	NA	NA	NA	NA
VFI45163.1\|863573_863801_+	TfoX N- domain family protein	NA	NA	NA	NA
VFI45167.1\|864204_864480_-	alanine dehydrogenase	NA	NA	NA	NA
VFI45173.1\|864476_865304_-	alanine dehydrogenase	NA	NA	NA	NA
VFI45180.1\|865480_866050_+	acetyltransferase	NA	NA	NA	NA
VFI45189.1\|866117_866768_+	competence protein	NA	NA	NA	NA
VFI45196.1\|866751_868992_+	competence protein CelB	M1PSD2	Streptococcus_phage	7.5e-46	52.2
VFI45203.1\|869391_869979_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-16	28.6
VFI45210.1\|869982_871167_+	ABC-type transport system involved in multi-copper enzyme maturation, permease component	NA	NA	NA	NA
VFI45217.1\|871420_872008_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.7e-11	32.1
VFI45224.1\|872040_872241_+	LSU ribosomal protein L35p	NA	NA	NA	NA
VFI45230.1\|872292_872652_+	LSU ribosomal protein L20p	NA	NA	NA	NA
VFI45237.1\|872709_873090_+	lactoylglutathione lyase	NA	NA	NA	NA
VFI45244.1\|873339_874140_+	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
VFI45250.1\|874150_875089_+	dihydroorotate dehydrogenase 1B	NA	NA	NA	NA
VFI45256.1\|875187_877296_+	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A143FPM9	Bacillus_phage	9.0e-25	42.6
VFI45262.1\|877356_879012_-	fibronectin/fibrinogen binding protein	A0A1J0F9J4	Only_Syngen_Nebraska_virus	4.7e-05	36.5
VFI45268.1\|879116_879614_+\|protease	putative metalloprotease	NA	NA	NA	NA
VFI45274.1\|879594_879990_+	diacylglycerol kinase	NA	NA	NA	NA
VFI45280.1\|880006_880906_+	GTP-binding protein Era	NA	NA	NA	NA
VFI45286.1\|880954_881779_+	formamidopyrimidine-DNA glycosylase	G3MA33	Bacillus_virus	2.1e-30	34.5
VFI45288.1\|881778_882384_+	dephospho-CoA kinase	NA	NA	NA	NA
VFI45294.1\|882370_883570_+	multidrug resistance protein MdtG	NA	NA	NA	NA
VFI45300.1\|883758_883992_+	membrane protein involved in protein export SecG	NA	NA	NA	NA
VFI45306.1\|884093_886448_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.4e-90	40.6
VFI45311.1\|886410_886878_+	SsrA-binding protein	W5RAM5	Staphylococcus_phage	2.1e-43	59.4
VFI45317.1\|886893_887754_+	tellurite resistance protein TehB	NA	NA	NA	NA
VFI45323.1\|887826_888780_+	competence protein	NA	NA	NA	NA
VFI45330.1\|888798_890601_+	oligoendopeptidase F	NA	NA	NA	NA
VFI45336.1\|890602_891316_+	O-methyltransferase	NA	NA	NA	NA
VFI45342.1\|891382_892324_+	peptidyl-prolyl isomerase	NA	NA	NA	NA
VFI45348.1\|892442_892784_-\|integrase	integrase core subunit	A0A0C5AEA5	Paenibacillus_phage	2.2e-13	42.6
VFI45354.1\|892783_892975_-\|transposase	degenerate transposase (orf1)	NA	NA	NA	NA
VFI45360.1\|893544_894165_-	phosphoglycerate mutase	NA	NA	NA	NA
VFI45366.1\|894164_894647_-	regulatory protein	NA	NA	NA	NA
VFI45373.1\|894646_895489_-	integral membrane protein	NA	NA	NA	NA
VFI45379.1\|895583_896384_-	lysozyme	NA	NA	NA	NA
VFI45385.1\|896527_897907_+	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	A0A2K9L277	Tupanvirus	1.3e-32	35.5
VFI45391.1\|897916_898462_+	MutT/NUDIX hydrolase family protein	NA	NA	NA	NA
VFI45397.1\|898473_898788_+	membrane protein	NA	NA	NA	NA
VFI45403.1\|898804_899497_+	5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
VFI45409.1\|899573_900065_+	DNA-binding protein	NA	NA	NA	NA
VFI45415.1\|900162_900753_+	DNA polymerase III subunit epsilon	NA	NA	NA	NA
VFI45417.1\|900761_902525_+	glycerophosphoryl diester phosphodiesterase family protein	A0A0S2MYI4	Enterococcus_phage	3.0e-05	22.2
901196:901211	attR	NA	NA	NA	NA
VFI45424.1\|902720_903068_+\|transposase	IS630-Spn1, transposase Orf1	NA	NA	NA	NA

DBSCAN-SWA_10

962062 : 994201

Streptococcus_phage(30.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI45793.1\|962062_962731_+\|transposase	degenerate transposase	NA	NA	NA	NA
VFI45799.1\|962832_963018_+\|transposase	degenerate transposase	NA	NA	NA	NA
VFI45805.1\|963120_963486_+	Uncharacterised protein	NA	NA	NA	NA
VFI45811.1\|964538_964889_+	Uncharacterised protein	NA	NA	NA	NA
VFI45814.1\|964947_965622_+	chloramphenicol acetyltransferase	NA	NA	NA	NA
VFI45820.1\|965689_967327_+\|tRNA	methionyl-tRNA synthetase	A0A167RM67	Powai_lake_megavirus	2.5e-75	32.0
VFI45824.1\|967427_968195_+	Protein tyrosine phosphatase	NA	NA	NA	NA
VFI45831.1\|969217_969559_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
VFI45837.1\|969619_970204_+	ABC transporter	A0A2R8FG22	Brazilian_cedratvirus	2.2e-05	33.0
VFI45844.1\|970205_970766_+	daunorubicin resistance transmembrane protein	NA	NA	NA	NA
VFI45851.1\|971024_971810_+	ABC transporter permease	NA	NA	NA	NA
VFI45857.1\|972442_972763_-\|transposase	degenerate transposase	A0A1X9I5Z0	Streptococcus_phage	8.2e-23	74.4
VFI45863.1\|973246_973462_-\|transposase	degenerate transposase	A0A1X9I5Z0	Streptococcus_phage	5.2e-13	82.2
VFI45869.1\|973885_974089_+	Cro/CI family transcriptional regulator	A0A139ZPI6	Marinitoga_camini_virus	6.4e-05	39.3
VFI45874.1\|974335_974485_+	Uncharacterised protein	NA	NA	NA	NA
VFI45879.1\|974538_976332_+\|tRNA	methionyl-tRNA synthetase	A0A2I4R675	Erysipelothrix_phage	4.0e-151	51.8
VFI45885.1\|976454_977024_+	peptidase	NA	NA	NA	NA
VFI45892.1\|977293_977542_+	phosphotransferase	NA	NA	NA	NA
VFI45898.1\|977646_977841_+\|transposase	transposase-like protein, IS1381 ISSpn7	NA	NA	NA	NA
VFI45904.1\|978103_979333_+	cell division protein FtsW	NA	NA	NA	NA
VFI45910.1\|979352_982049_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
VFI45916.1\|982461_983466_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
VFI45922.1\|983534_984401_+	ABC transporter, membrane-spanning permease	NA	NA	NA	NA
VFI45931.1\|984397_985156_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.7e-13	27.7
VFI45937.1\|985245_987006_+	DNA primase	A0A1S5RH72	Helicobacter_phage	2.9e-45	28.7
VFI45943.1\|987008_988118_+	RNA polymerase sigma factor RpoD	F4YCU2	Synechococcus_phage	2.0e-36	38.5
VFI45950.1\|988131_988461_+	metal-sulfur cluster biosynthesis protein	NA	NA	NA	NA
VFI45956.1\|988575_989619_+	glycosyl transferase CpoA	NA	NA	NA	NA
VFI45962.1\|989634_990960_+	glycosyltransferase, group 1 family protein	NA	NA	NA	NA
VFI45968.1\|990990_991167_+	putative stress-responsive transcriptional regulator	NA	NA	NA	NA
VFI45975.1\|991225_991360_+	Uncharacterised protein	NA	NA	NA	NA
VFI45980.1\|991423_992734_+	GTP-binding protein	NA	NA	NA	NA
VFI45986.1\|992743_992902_+	putative extracellular protein	NA	NA	NA	NA
VFI45992.1\|992953_994201_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.2e-210	88.2

DBSCAN-SWA_11

999473 : 1040662

Bacillus_phage(28.57%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI46022.1\|999473_999794_+\|transposase	transposase	NA	NA	NA	NA
VFI46028.1\|999836_1000145_+\|transposase	degenerate transposase	NA	NA	NA	NA
VFI46034.1\|1000095_1000560_+\|transposase	transposase	NA	NA	NA	NA
VFI46040.1\|1000750_1003042_+	ATP-dependent DNA helicase PcrA	A7KV33	Bacillus_phage	9.5e-129	41.1
VFI46046.1\|1003084_1003765_+	DNA repair protein RadC	NA	NA	NA	NA
VFI46052.1\|1003761_1004451_-	glutamine amidotransferase, class I	NA	NA	NA	NA
VFI46058.1\|1004468_1005110_-	DNA-binding protein	NA	NA	NA	NA
VFI46065.1\|1005192_1005408_-	Uncharacterised protein	NA	NA	NA	NA
VFI46071.1\|1005415_1005763_-	cytosolic protein	NA	NA	NA	NA
VFI46077.1\|1005767_1006883_-	aminotransferase class-V	H7BUW1	unidentified_phage	1.0e-27	36.8
VFI46083.1\|1006892_1007852_-	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	9.3e-38	32.8
VFI46089.1\|1007964_1008534_-	adenylate cyclase	NA	NA	NA	NA
VFI46095.1\|1008661_1009333_+	GTP pyrophosphokinase	NA	NA	NA	NA
VFI46101.1\|1009316_1010135_+	putative sugar kinase	NA	NA	NA	NA
VFI46107.1\|1010131_1011028_+	23S_rRNA pseudouridine synthase	NA	NA	NA	NA
VFI46113.1\|1011071_1012046_+	phosphotransacetylase	NA	NA	NA	NA
VFI46119.1\|1012386_1012686_-	hypothetical cytosolic protein	NA	NA	NA	NA
VFI46125.1\|1013099_1013786_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
VFI46131.1\|1013973_1014288_+	50S ribosomal protein L21	NA	NA	NA	NA
VFI46137.1\|1014303_1014648_+	ribosomal protein	NA	NA	NA	NA
VFI46143.1\|1014664_1014958_+	LSU ribosomal protein L27p	NA	NA	NA	NA
VFI46149.1\|1015911_1016829_+	bifunctional riboflavin kinase/FMN adenylyltransferase	NA	NA	NA	NA
VFI46155.1\|1016921_1017770_-	YpjC	M1Q1P6	Streptococcus_phage	1.4e-64	46.5
VFI46161.1\|1017911_1018751_+	DegV family protein	NA	NA	NA	NA
VFI46167.1\|1018857_1019133_+	DNA-binding protein HU 1	A7KV42	Bacillus_phage	9.2e-23	66.3
VFI46173.1\|1019351_1019654_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	2.2e-49	94.9
VFI46179.1\|1019768_1020005_-\|transposase	IS630-Spn1, transposase Orf2	NA	NA	NA	NA
VFI46185.1\|1020182_1020533_-\|transposase	IS630-Spn1, transposase Orf1	NA	NA	NA	NA
VFI46192.1\|1021058_1024334_+	exonuclease RexB	NA	NA	NA	NA
VFI46198.1\|1024330_1027981_+	ATP-dependent exoDNAse subunit beta	G3MA40	Bacillus_virus	5.7e-19	24.8
VFI46204.1\|1028150_1029329_+	Uncharacterised protein	NA	NA	NA	NA
VFI46210.1\|1029537_1035213_+\|protease	immunoglobulin A1 protease	NA	NA	NA	NA
VFI46213.1\|1035256_1040662_+\|protease	zinc metalloprotease ZmpD	NA	NA	NA	NA

DBSCAN-SWA_12

1067849 : 1118037

Streptococcus_phage(16.67%)

transposase,bacteriocin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI46368.1\|1067849_1068137_-\|transposase	degenerate transposase	A0A1S5SBP9	Streptococcus_phage	1.1e-21	67.1
VFI46374.1\|1068133_1068652_-\|transposase	IS1167 transposase	A0A1S5SBP9	Streptococcus_phage	5.9e-79	91.7
VFI46376.1\|1068961_1069723_+	lactose phosphotransferase system repressor	NA	NA	NA	NA
VFI46380.1\|1070303_1071710_-	6-phospho-beta-galactosidase	NA	NA	NA	NA
VFI46386.1\|1071924_1073619_-	PTS system lactose-specific transporter subunit IIBC	NA	NA	NA	NA
VFI46394.1\|1073620_1073938_-	PTS system lactose-specific transporter subunit IIA	NA	NA	NA	NA
VFI46400.1\|1073973_1074810_-	transcription antiterminator LacT	NA	NA	NA	NA
VFI46406.1\|1075043_1076024_-	tagatose 1,6-diphosphate aldolase	NA	NA	NA	NA
VFI46413.1\|1076025_1076955_-	tagatose-6-phosphate kinase	NA	NA	NA	NA
VFI46419.1\|1076965_1077481_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
VFI46425.1\|1077511_1077937_-	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
VFI46431.1\|1078093_1078570_-	galactose mutarotase-like enzyme	NA	NA	NA	NA
VFI46437.1\|1078606_1078996_-\|transposase	transposase	NA	NA	NA	NA
VFI46443.1\|1079141_1079426_-\|transposase	IS1381, transposase OrfA	NA	NA	NA	NA
VFI46449.1\|1079433_1079736_-	PTS system galactose-specific transporter subunit IIB	NA	NA	NA	NA
VFI46455.1\|1079773_1080250_-	PTS system transporter subunit IIA	NA	NA	NA	NA
VFI46461.1\|1080707_1082531_-	GTP-binding protein LepA	A0A2K9L2P9	Tupanvirus	2.9e-19	41.0
VFI46467.1\|1082609_1083338_-	serine/threonine protein phosphatase	A0A1V0EC57	Caulobacter_phage	1.4e-14	33.0
VFI46478.1\|1083339_1085007_-	DNA repair protein RecN	NA	NA	NA	NA
VFI46484.1\|1085013_1085445_-	transcriptional repressor protein	NA	NA	NA	NA
VFI46490.1\|1085437_1086253_-	rRNA methylase	NA	NA	NA	NA
VFI46496.1\|1086245_1087121_-	farnesyl diphosphate synthase	NA	NA	NA	NA
VFI46502.1\|1087117_1087330_-	exodeoxyribonuclease VII, small subunit	NA	NA	NA	NA
VFI46510.1\|1087307_1088648_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	3.9e-34	33.6
VFI46516.1\|1088775_1089414_-	uridine kinase	A0A1V0SAA3	Catovirus	8.4e-35	39.9
VFI46522.1\|1089521_1089824_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
VFI46528.1\|1089820_1089916_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
VFI46534.1\|1090069_1090948_-\|tRNA	tRNA pseudouridine synthase B	NA	NA	NA	NA
VFI46537.1\|1091048_1094234_-	membrane protein	NA	NA	NA	NA
VFI46544.1\|1094245_1095520_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VFI46550.1\|1095690_1096731_-	O-acetylhomoserine sulfhydrylase	NA	NA	NA	NA
VFI46556.1\|1096752_1096875_-	O-acetylhomoserine sulfhydrylase	NA	NA	NA	NA
VFI46564.1\|1097022_1097820_-	formate/nitrate transporter	NA	NA	NA	NA
VFI46570.1\|1098063_1098807_-	sortase SrtA	NA	NA	NA	NA
VFI46575.1\|1098806_1101275_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	3.5e-105	35.5
VFI46581.1\|1101468_1102455_+	L-lactate dehydrogenase 1	NA	NA	NA	NA
VFI46588.1\|1102782_1103367_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	1.6e-16	46.9
VFI46598.1\|1103413_1103677_-	cytotoxic translational repressor of toxin-antitoxin stability system	NA	NA	NA	NA
VFI46603.1\|1103669_1103912_-	toxin-antitoxin system, antitoxin component, ribbon-helix-helix fold protein	NA	NA	NA	NA
VFI46609.1\|1104002_1104812_-	metallo-beta-lactamase superfamily protein	A0A0C5AFC1	Paenibacillus_phage	1.8e-34	39.0
VFI46615.1\|1104813_1106163_-	histidine kinase	W8CYF6	Bacillus_phage	8.8e-34	34.3
VFI46621.1\|1106155_1106860_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	2.8e-39	39.8
VFI46627.1\|1106914_1108090_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
VFI46633.1\|1108418_1110089_-	formate-tetrahydrofolate ligase	NA	NA	NA	NA
VFI46639.1\|1110318_1111008_+	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
VFI46645.1\|1111019_1111571_+	flavoprotein involved in panthothenate metabolism	A0A068EHP1	Penguinpox_virus	3.1e-25	37.6
VFI46651.1\|1111554_1112118_+	membrane protein	NA	NA	NA	NA
VFI46657.1\|1112399_1112927_+	membrane protein	NA	NA	NA	NA
VFI46663.1\|1112938_1113454_+	transcriptional regulator	NA	NA	NA	NA
VFI46669.1\|1113450_1113918_-	MutT/nudix family protein	NA	NA	NA	NA
VFI46675.1\|1113991_1114480_-	acetyltransferase, gnat family	NA	NA	NA	NA
VFI46681.1\|1114445_1115009_-	acetyltransferase	NA	NA	NA	NA
VFI46688.1\|1115018_1117007_-	excinuclease ABC subunit B	NA	NA	NA	NA
VFI46694.1\|1117083_1118037_-\|protease	caax amino protease family protein	NA	NA	NA	NA

DBSCAN-SWA_13

1144272 : 1179561

Indivirus(20.0%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI46832.1\|1144272_1145226_+\|transposase	IS1239 transposase	H7BWC8	unidentified_phage	1.6e-34	35.2
VFI46838.1\|1145899_1146748_-	DNA processing protein DprA	S6BFL3	Thermus_phage	4.2e-34	39.5
VFI46844.1\|1146843_1147533_-\|holin	CTP:phosphocholine cytidylyltransferase	A0A127AW70	Bacillus_phage	3.4e-05	45.0
VFI46850.1\|1147544_1148423_-	drug/metabolite transporter (DMT) superfamily permease	NA	NA	NA	NA
VFI46856.1\|1148412_1149282_-\|holin	choline kinase	NA	NA	NA	NA
VFI46862.1\|1149298_1150321_-	zinc-containing alcohol dehydrogenase	NA	NA	NA	NA
VFI46868.1\|1150325_1151033_-	cytidylyltransferase	NA	NA	NA	NA
VFI46874.1\|1151368_1152856_+	teichoic acid subunit flippase	NA	NA	NA	NA
VFI46882.1\|1152865_1153669_+\|holin	phosphorylcholine transferase LicD1	A0A1V0SD50	Indivirus	5.3e-10	27.1
VFI46887.1\|1153670_1154480_+	licD2 protein	A0A1V0SD50	Indivirus	9.1e-10	30.3
VFI46893.1\|1154754_1157931_-	carbamoyl-phosphate synthase, large subunit	NA	NA	NA	NA
VFI46899.1\|1158243_1159323_-	carbamoyl-phosphate synthase, small subunit	R4TGJ8	Halovirus	6.3e-59	35.9
VFI46905.1\|1159372_1160296_-	aspartate carbamoyltransferase	M1HGA5	Paramecium_bursaria_Chlorella_virus	8.7e-25	31.7
VFI46911.1\|1160314_1160836_-	transcriptional attenuation of the pyrimidine operon/uracil phosphoribosyltransferase (bifunctional protein)	NA	NA	NA	NA
VFI46919.1\|1161046_1161676_-	endonuclease III (DNA repair), DNA-(apurinic or apyrimidinic site) lyase	NA	NA	NA	NA
VFI46925.1\|1161675_1162218_-	putative metal-binding, possibly nucleic acid-binding protein	NA	NA	NA	NA
VFI46931.1\|1162387_1162705_+	BlpT protein, fusion	NA	NA	NA	NA
VFI46937.1\|1162943_1164503_+	ABC transporter ATP-binding protein	A0A1B0RXA0	Streptococcus_phage	9.3e-11	27.5
VFI46943.1\|1164651_1165551_-	heat shock protein HtpX	NA	NA	NA	NA
VFI46949.1\|1165552_1166113_-	Cytoplasmic membrane protein LemA	NA	NA	NA	NA
VFI46955.1\|1166206_1166920_+	16S rRNA methyltransferase GidB	NA	NA	NA	NA
VFI46961.1\|1167271_1168555_+	uracil permease	Q9KX94	Enterobacteria_phage	4.0e-60	35.3
VFI46967.1\|1168749_1170321_-	signal recognition particle protein	NA	NA	NA	NA
VFI46973.1\|1170332_1170665_-	transcriptional regulator	NA	NA	NA	NA
VFI46979.1\|1170755_1171133_-	hypothetical cytosolic protein	NA	NA	NA	NA
VFI46985.1\|1171204_1172509_+	dGTP triphosphohydrolase	E3T4P8	Cafeteria_roenbergensis_virus	1.7e-26	30.2
VFI46991.1\|1172521_1173328_+	hydrolase	NA	NA	NA	NA
VFI46997.1\|1173538_1175314_-	Lmo0466 protein	NA	NA	NA	NA
VFI47003.1\|1175799_1176981_-\|holin	choline binding protein PcpA	NA	NA	NA	NA
VFI47010.1\|1176993_1178214_-	surface protein A	NA	NA	NA	NA
VFI47013.1\|1178307_1179162_+	rgg protein	NA	NA	NA	NA
VFI47019.1\|1179393_1179561_-\|transposase	IS861, transposase OrfA	NA	NA	NA	NA

DBSCAN-SWA_14

1274369 : 1321806

Streptococcus_phage(31.25%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI47578.1\|1274369_1274612_-\|transposase	transposase	NA	NA	NA	NA
VFI47585.1\|1275211_1275679_-\|transposase	transposase	NA	NA	NA	NA
VFI47590.1\|1276059_1276296_-\|transposase	transposase	NA	NA	NA	NA
VFI47595.1\|1276276_1276462_-	IS66 family Orf1	NA	NA	NA	NA
VFI47600.1\|1276765_1278328_-	GMP synthase	A0A1V0SH76	Hokovirus	1.4e-19	32.8
VFI47605.1\|1278469_1279168_+	GntR family transcriptional regulator	NA	NA	NA	NA
VFI47610.1\|1279210_1280107_-	membrane protein	NA	NA	NA	NA
VFI47615.1\|1280115_1281051_-	beta-lactamase	NA	NA	NA	NA
VFI47620.1\|1281047_1281773_-	cppA protein	NA	NA	NA	NA
VFI47625.1\|1281856_1282492_-	lysophospholipase l1-like esterase	A0A2K9L661	Tupanvirus	7.4e-07	28.2
VFI47630.1\|1282493_1283321_-	hydrolase	NA	NA	NA	NA
VFI47635.1\|1283342_1283678_-	poly-gamma-glutamate biosynthesis protein	NA	NA	NA	NA
VFI47639.1\|1283678_1284191_-	enzyme of poly-gamma-glutamate biosynthesis	A0A0N9SJ77	Staphylococcus_phage	7.0e-16	30.8
VFI47644.1\|1284919_1285531_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
VFI47649.1\|1285575_1286304_+	TrmH family RNA methyltransferase group 3	NA	NA	NA	NA
VFI47654.1\|1286342_1287254_-	thioredoxin reductase	G3MA85	Bacillus_virus	3.8e-89	51.1
VFI47659.1\|1287319_1287544_-	membrane associated protein	NA	NA	NA	NA
VFI47664.1\|1287621_1288365_-	aspartate/glutamate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	40.5
VFI47669.1\|1288364_1289165_-	aspartate/glutamate ABC transporter permease	NA	NA	NA	NA
VFI47672.1\|1289322_1289679_-	ArsC family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
VFI47677.1\|1289691_1290204_-	O6-methylguanine-DNA methyltransferase	M1PFU9	Streptococcus_phage	1.3e-46	55.6
VFI47682.1\|1290203_1290698_-	acetyltransferase, GNAT family protein	M1PSC3	Streptococcus_phage	2.9e-43	52.8
VFI47687.1\|1290832_1291279_+	BS_ykrK family protein	NA	NA	NA	NA
VFI47692.1\|1291275_1291923_+	hlyIII superfamily protein	NA	NA	NA	NA
VFI47697.1\|1292274_1293591_-	ABC transporter	NA	NA	NA	NA
VFI47702.1\|1293608_1294340_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
VFI47707.1\|1294896_1295481_-	glutamine amidotransferase subunit PdxT	NA	NA	NA	NA
VFI47711.1\|1295481_1296357_-	pyridoxal biosynthesis lyase PdxS	NA	NA	NA	NA
VFI47716.1\|1296508_1297888_-	NADH oxidase	NA	NA	NA	NA
VFI47721.1\|1298181_1299105_+	thiamine biosynthesis lipoprotein	NA	NA	NA	NA
VFI47726.1\|1299164_1299770_+	NADPH-dependent FMN reductase domain-containing protein	A0A2P0ZL77	Lactobacillus_phage	2.2e-53	53.7
VFI47731.1\|1299788_1301033_+	flavin reductase	A0A2P0ZL82	Lactobacillus_phage	3.8e-55	52.7
VFI47736.1\|1301255_1301513_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VFI47741.1\|1301554_1303591_-\|tRNA	glycyl-tRNA synthetase beta subunit	NA	NA	NA	NA
VFI47746.1\|1303850_1304768_-\|tRNA	glycyl-tRNA synthetase alpha subunit	NA	NA	NA	NA
VFI47751.1\|1304961_1305288_-	Uncharacterised protein	NA	NA	NA	NA
VFI47755.1\|1305391_1305724_-	Uncharacterised protein	NA	NA	NA	NA
VFI47759.1\|1305996_1306839_-	2,5-diketo-D-gluconic acid reductase A	A0A2H4PQR8	Staphylococcus_phage	1.3e-51	40.2
VFI47763.1\|1306952_1308395_-	peptidoglycan N-acetylglucosamine deacetylase A	NA	NA	NA	NA
VFI47767.1\|1308578_1308809_-	ribose-phosphate pyrophosphokinase	NA	NA	NA	NA
VFI47771.1\|1309189_1310167_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
VFI47775.1\|1310163_1311246_+	ATP-dependent RNA helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-32	29.6
VFI47779.1\|1311309_1311819_-\|transposase	transposase family protein	NA	NA	NA	NA
VFI47783.1\|1312933_1314130_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	7.3e-32	29.6
VFI47787.1\|1315050_1315920_-	glycerol facilitator-aquaporin	NA	NA	NA	NA
VFI47791.1\|1316142_1316664_-	putative sortase-sorted surface anchored protein (pseudogene)	NA	NA	NA	NA
VFI47795.1\|1316621_1317728_-	putative sortase-sorted surface anchored protein (pseudogene)	NA	NA	NA	NA
VFI47799.1\|1317838_1318093_-	Uncharacterised protein	NA	NA	NA	NA
VFI47803.1\|1318432_1318732_-\|transposase	degenerate transposase	NA	NA	NA	NA
VFI47807.1\|1319510_1321229_+	phosphoglucomutase	A0A1X9I671	Streptococcus_phage	5.8e-272	83.0
VFI47811.1\|1321278_1321806_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.4e-88	95.4

DBSCAN-SWA_15

1339753 : 1359428

Streptococcus_phage(81.82%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI47870.1\|1339753_1340572_+	glycerate kinase	W6LM47	Streptococcus_phage	2.4e-42	49.4
VFI47874.1\|1340552_1340870_+	glycerate kinase-family protein	W6LM47	Streptococcus_phage	6.9e-22	51.0
VFI47877.1\|1340866_1341313_-	Uncharacterized conserved protein	NA	NA	NA	NA
VFI47881.1\|1341476_1342781_+	Enolase	W6LP63	Streptococcus_phage	8.1e-234	94.2
VFI47885.1\|1342955_1343483_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	8.3e-89	96.0
VFI47889.1\|1343479_1343767_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	8.7e-24	71.8
VFI47895.1\|1343763_1344135_-\|transposase	degenerate transposase	A0A1S5SBP9	Streptococcus_phage	3.4e-52	94.4
VFI47899.1\|1344218_1344500_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	1.4e-42	94.5
VFI47903.1\|1344496_1344784_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	8.7e-24	71.8
VFI47907.1\|1344780_1345299_-\|transposase	degenerate transposase	A0A1S5SBP9	Streptococcus_phage	3.3e-82	96.2
VFI47911.1\|1345525_1345873_+\|bacteriocin	thioredoxin, bacteriocin transport accessory protein	NA	NA	NA	NA
VFI47914.1\|1346152_1346989_-	glutamine ABC transporter substrate-binding protein	NA	NA	NA	NA
VFI47918.1\|1347001_1347631_-	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-28	37.3
VFI47922.1\|1347640_1348282_-	amino acid ABC transporter permease	NA	NA	NA	NA
VFI47927.1\|1348427_1349657_-	TPR domain protein	NA	NA	NA	NA
VFI47931.1\|1349646_1350813_-	transport protein	NA	NA	NA	NA
VFI47935.1\|1350956_1351970_+	3-carboxymuconate cyclase	NA	NA	NA	NA
VFI47939.1\|1352014_1352434_-	proton-translocating ATPase, F1 sector, epsilon-subunit	NA	NA	NA	NA
VFI47943.1\|1352444_1353851_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
VFI47948.1\|1353936_1354815_-	proton-translocating ATPase, F1 sector, gamma-subunit	NA	NA	NA	NA
VFI47952.1\|1354830_1356336_-	ATP synthase subunit alpha	NA	NA	NA	NA
VFI47957.1\|1356350_1356887_-	proton-translocating ATPase, F1 sector, delta-subunit	NA	NA	NA	NA
VFI47961.1\|1356886_1357381_-	proton-translocating ATPase, F0 sector, subunit b	NA	NA	NA	NA
VFI47965.1\|1357394_1358111_-	ATP synthase F0 subunit A	NA	NA	NA	NA
VFI47969.1\|1358145_1358346_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
VFI47973.1\|1358420_1359428_-\|transposase	IS1239 transposase	H7BVY4	unidentified_phage	5.4e-36	35.7

DBSCAN-SWA_16

1407446 : 1470590

Streptococcus_phage(28.57%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI48175.1\|1407446_1408412_+	thioredoxin reductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
VFI48179.1\|1408445_1409357_-	putative sporulation transcription regulator whiA	Q7AWZ3	Streptococcus_phage	9.8e-154	99.3
VFI48184.1\|1409353_1410331_-	transporter	A1IMD5	Streptococcus_phage	4.4e-184	99.7
VFI48188.1\|1410327_1411218_-	P-loop-containing kinase	A0A0R8VB27	Thermobifida_phage	3.9e-06	29.8
VFI48192.1\|1411269_1411650_-	endoribonuclease L-PSP	NA	NA	NA	NA
VFI48196.1\|1411660_1412248_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
VFI48200.1\|1412256_1413489_-\|protease	ATP-dependent Clp protease, ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.2e-131	59.0
VFI48204.1\|1413520_1413691_-	membrane associated protein	NA	NA	NA	NA
VFI48208.1\|1413690_1414197_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	2.1e-25	40.6
VFI48212.1\|1414324_1414843_-	DPS family peroxide resistance protein	NA	NA	NA	NA
VFI48216.1\|1415340_1416813_-	1,4-beta-N-acetylmuramidase	NA	NA	NA	NA
VFI48220.1\|1416882_1417641_-	triosephosphate isomerase	NA	NA	NA	NA
VFI48224.1\|1417738_1418416_-	DNA replication protein	A0A1X9I617	Streptococcus_phage	2.2e-09	41.3
VFI48227.1\|1418424_1419369_-	homoserine O-succinyltransferase	NA	NA	NA	NA
VFI48231.1\|1419550_1420063_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	9.1e-32	47.3
VFI48235.1\|1420149_1420908_-	methyltransferase type 11	NA	NA	NA	NA
VFI48239.1\|1421408_1422539_-	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-20	33.2
VFI48244.1\|1422988_1423564_-	amidases related to nicotinamidase	G3MA16	Bacillus_virus	3.3e-22	35.9
VFI48248.1\|1423563_1424352_-	GTP-sensing transcriptional pleiotropic repressor	NA	NA	NA	NA
VFI48252.1\|1424615_1426190_-	ATP-dependent RNA helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.4e-59	36.8
VFI48256.1\|1426388_1427615_-	major facilitator; oxalate:formate antiporter	NA	NA	NA	NA
VFI48260.1\|1427807_1429124_+	oxidoreductase, pyridine nucleotide-disulfide class I, Mercury (II) reductase	A0A2K5B2C5	Erysipelothrix_phage	2.2e-98	44.1
VFI48264.1\|1429222_1430566_+	UDP-N-acetylmuramyl tripeptide synthetase, Mur ligase	NA	NA	NA	NA
VFI48267.1\|1430565_1431348_+	cobyric acid synthase	NA	NA	NA	NA
VFI48271.1\|1431473_1432556_+	X-Pro dipeptidase	NA	NA	NA	NA
VFI48275.1\|1432876_1433710_-\|transposase	IS3-Spn1, transposase	A0A1B1P773	Bacillus_phage	2.1e-57	48.1
VFI48279.1\|1433709_1433877_-\|transposase	transposase	NA	NA	NA	NA
VFI48283.1\|1434012_1434282_-\|transposase	degenerate transposase (Orf1)	NA	NA	NA	NA
VFI48287.1\|1434452_1434914_-	integral membrane protein	NA	NA	NA	NA
VFI48291.1\|1434891_1435665_-	phosphomethylpyrimidine kinase	NA	NA	NA	NA
VFI48295.1\|1435654_1436404_-\|tRNA	tRNA pseudouridine synthase A	NA	NA	NA	NA
VFI48298.1\|1436721_1437873_-	major facilitator superfamily transporter-efflux	NA	NA	NA	NA
VFI48302.1\|1438112_1438742_-	membrane protein	NA	NA	NA	NA
VFI48305.1\|1438744_1439083_-	phnA protein	NA	NA	NA	NA
VFI48308.1\|1439213_1439885_-	cytidylate kinase	NA	NA	NA	NA
VFI48311.1\|1439893_1440370_-	30S ribosomal protein S15	NA	NA	NA	NA
VFI48314.1\|1440415_1440628_+	ferredoxin	NA	NA	NA	NA
VFI48317.1\|1440818_1441463_-	Uncharacterised protein	NA	NA	NA	NA
VFI48320.1\|1441635_1442589_-	glycosil transferase	V5USA4	Oenococcus_phage	5.6e-75	48.9
VFI48323.1\|1442572_1443592_-	UDP-glucose 4-epimerase	A0A2K9L5H6	Tupanvirus	3.6e-88	48.5
VFI48326.1\|1443892_1444996_-	oxidoreductase, DadA family protein	NA	NA	NA	NA
VFI48329.1\|1445012_1445810_-	NIF3 (NGG1p interacting factor 3) family protein	NA	NA	NA	NA
VFI48332.1\|1445796_1446474_-	Bcl-2 family protein	NA	NA	NA	NA
VFI48335.1\|1446831_1446936_+	Uncharacterised protein	NA	NA	NA	NA
VFI48338.1\|1447022_1448015_+	serine/threonine protein kinase	NA	NA	NA	NA
VFI48341.1\|1448088_1449525_+	lanthionine synthetase C-like protein	NA	NA	NA	NA
VFI48344.1\|1449526_1450765_+	MFS transporter	NA	NA	NA	NA
VFI48347.1\|1450977_1454100_+	snf2 family protein	A0A0P0YMN2	Yellowstone_lake_phycodnavirus	2.4e-50	32.2
VFI48350.1\|1454536_1456873_-	P-type ATPase-metal cation transport	M1HRW9	Paramecium_bursaria_Chlorella_virus	2.1e-35	26.2
VFI48354.1\|1457005_1457755_+	acyltransferase family protein	NA	NA	NA	NA
VFI48357.1\|1458046_1458661_-	Cad superfamily protein	NA	NA	NA	NA
VFI48360.1\|1459476_1459746_-	30S ribosomal protein S15	NA	NA	NA	NA
VFI48363.1\|1459886_1460516_-	YwnB	NA	NA	NA	NA
VFI48366.1\|1460754_1460955_+	Uncharacterised protein	NA	NA	NA	NA
VFI48369.1\|1461385_1461709_+	30S ribosomal protein S15	NA	NA	NA	NA
VFI48372.1\|1461766_1463710_+\|tRNA	threonyl-tRNA synthetase	A0A2K9L297	Tupanvirus	5.6e-122	39.1
VFI48376.1\|1463758_1464733_-	histidine kinase	B5LWN0	Feldmannia_species_virus	1.4e-09	26.6
VFI48379.1\|1464725_1465403_-	DNA-binding response regulator	NA	NA	NA	NA
VFI48382.1\|1465558_1466632_+	lipase	NA	NA	NA	NA
VFI48385.1\|1466795_1467026_-	Uncharacterised protein	NA	NA	NA	NA
VFI48388.1\|1467094_1467532_-	RRF2 family protein	NA	NA	NA	NA
VFI48391.1\|1467607_1468450_-	serine/threonine protein phosphatase family protein	NA	NA	NA	NA
VFI48394.1\|1468561_1469212_+	iron-dependent transcriptional regulator	NA	NA	NA	NA
VFI48397.1\|1469283_1469811_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	5.8e-90	96.0
VFI48400.1\|1469807_1470590_-\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	5.0e-114	83.6

DBSCAN-SWA_17

1687905 : 1744628

Streptococcus_phage(28.57%)

transposase,integrase,holin

attL 1688007:1688024|attR 1742119:1742136

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI49090.1\|1687905_1689426_-\|holin	choline transporter	NA	NA	NA	NA
1688007:1688024	attL	NA	NA	NA	NA
VFI49094.1\|1689418_1690147_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-32	41.2
VFI49098.1\|1690161_1690926_-	lipoprotein	NA	NA	NA	NA
VFI49101.1\|1690929_1691373_-	transcriptional regulator, MarR family	NA	NA	NA	NA
VFI49104.1\|1692054_1692351_-	Enterocin A Immunity	NA	NA	NA	NA
VFI49107.1\|1692372_1693437_-	glutamyl aminopeptidase	NA	NA	NA	NA
VFI49110.1\|1693837_1694539_+	putative UDP-glucose 4-epimerase	A0A2K9L1R4	Tupanvirus	4.1e-35	36.5
VFI49114.1\|1694961_1695921_+	iron-compound ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.0e-57	40.8
VFI49117.1\|1695910_1696867_+	ferric iron ABC transporter membrane-spanning permease	NA	NA	NA	NA
VFI49120.1\|1696863_1697616_+	ferrichrome transport ATP-binding protein FhuC	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-14	28.1
VFI49123.1\|1697711_1698677_+	iron-compound ABC transporter iron-compound-binding protein	NA	NA	NA	NA
VFI49127.1\|1698901_1699144_-	alpha-hemolysin family protein	A0A2H4PQM5	Staphylococcus_phage	1.0e-17	58.0
VFI49130.1\|1699143_1699866_-	ribosomal large subunit pseudouridine synthase B	NA	NA	NA	NA
VFI49134.1\|1699852_1700422_-	segregation and condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
VFI49137.1\|1700440_1701169_-	segregation and condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	6.9e-09	22.3
VFI49140.1\|1701168_1701903_-\|integrase	integrase	NA	NA	NA	NA
VFI49143.1\|1701899_1702361_-	CBS domain-containing protein	NA	NA	NA	NA
VFI49146.1\|1702357_1702879_-	phosphodiesterase, family	NA	NA	NA	NA
VFI49149.1\|1702854_1703826_-	deoxyribonucleotide triphosphate pyrophosphatase/uncharacterised domain fusion protein	C4N227	Ugandan_cassava_brown_streak_virus	4.9e-10	29.9
VFI49153.1\|1703822_1704617_-	glutamate racemase, COG0796	NA	NA	NA	NA
VFI49156.1\|1704823_1705072_-	family protein	NA	NA	NA	NA
VFI49159.1\|1705327_1706953_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
VFI49162.1\|1707130_1709098_-	trehalose PTS system, IIABC components	NA	NA	NA	NA
VFI49165.1\|1709282_1709993_+	trehalose operon repressor	NA	NA	NA	NA
VFI49168.1\|1710147_1710666_+\|transposase	degenerate transposase	A0A1S5SBP9	Streptococcus_phage	6.7e-83	96.8
VFI49172.1\|1710662_1710950_+\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-22	69.4
VFI49175.1\|1710946_1711474_+\|transposase	transposase	A0A1S5SBP9	Streptococcus_phage	3.4e-90	96.6
VFI49178.1\|1711548_1712475_-	oligopeptide ABC transporter ATP-binding protein AmiF	G9BWD6	Planktothrix_phage	2.0e-21	34.1
VFI49181.1\|1712485_1713553_-	peptide ABC transporter ATP-binding protein	A0A2R8FFL6	Cedratvirus	6.6e-08	24.7
VFI49184.1\|1713561_1714488_-	peptide ABC transporter permease	NA	NA	NA	NA
VFI49187.1\|1714487_1715984_-	peptide ABC transporter permease	NA	NA	NA	NA
VFI49190.1\|1716050_1718030_-	oligopeptide-binding protein AmiA	NA	NA	NA	NA
VFI49193.1\|1718715_1719909_-	O-Antigen Polymerase family	NA	NA	NA	NA
VFI49196.1\|1720046_1721489_-	sucrose phosphorylase	NA	NA	NA	NA
VFI49200.1\|1721846_1722680_-	sugar ABC transporter permease	NA	NA	NA	NA
VFI49203.1\|1722693_1723560_-	sugar ABC transporter permease	NA	NA	NA	NA
VFI49206.1\|1723573_1724833_-	sugar ABC transporter binding protein	NA	NA	NA	NA
VFI49209.1\|1724867_1727030_-	alpha-galactosidase	NA	NA	NA	NA
VFI49212.1\|1727137_1727998_+	Msm operon regulatory protein	NA	NA	NA	NA
VFI49215.1\|1727994_1728930_+	bifunctional protein, biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase	NA	NA	NA	NA
VFI49218.1\|1731706_1733062_-	RNA methyltransferase	E4ZFI6	Streptococcus_phage	2.0e-70	33.5
VFI49220.1\|1733118_1733895_+	aminoglycoside phosphotransferase	NA	NA	NA	NA
VFI49224.1\|1733904_1734681_+	regulatory protein RecX	NA	NA	NA	NA
VFI49228.1\|1734769_1735303_+	UPF0374 protein SSU05	NA	NA	NA	NA
VFI49231.1\|1735659_1735866_-	putative transcriptional regulator	NA	NA	NA	NA
VFI49234.1\|1741312_1741795_-	competence-specific global transcription modulator	NA	NA	NA	NA
VFI49237.1\|1742029_1742566_-	transcription antitermination protein NusG	NA	NA	NA	NA
1742119:1742136	attR	NA	NA	NA	NA
VFI49240.1\|1742620_1742797_-	preprotein translocase secE component, COG0690	NA	NA	NA	NA
VFI49244.1\|1743122_1744628_+\|transposase	IS1202 transposase	NA	NA	NA	NA

DBSCAN-SWA_18

1778315 : 1832511

Bacillus_virus(10.0%)

transposase,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI49349.1\|1778315_1780331_+\|bacteriocin	bacteriocin-associated integral membrane protein	NA	NA	NA	NA
VFI49351.1\|1780332_1780965_+	antimicrobial peptide ABC transporter ATPase	G3M9Y6	Bacillus_virus	2.8e-22	33.3
VFI49353.1\|1781122_1781284_+	competence damage-inducible protein A	NA	NA	NA	NA
VFI49355.1\|1781910_1782324_-	nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.5e-24	44.5
VFI49357.1\|1782434_1786112_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	2.4e-65	25.0
VFI49359.1\|1786144_1789756_-	DNA-directed RNA polymerase subunit beta	A0A2P0VMZ3	Tetraselmis_virus	1.2e-40	26.4
VFI49361.1\|1790439_1791771_-	CBS domain membrane protein	NA	NA	NA	NA
VFI49363.1\|1792061_1792886_-	DNA-entry nuclease (competence-specific nuclease)	NA	NA	NA	NA
VFI49365.1\|1792924_1793119_-	competence associated protein	NA	NA	NA	NA
VFI49367.1\|1793105_1794389_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
VFI49369.1\|1794412_1794610_-	membrane protein	NA	NA	NA	NA
VFI49372.1\|1794700_1795738_-\|protease	ATP-dependent protease La	NA	NA	NA	NA
VFI49374.1\|1795721_1796210_-	phosphopantetheine adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	3.0e-16	32.5
VFI49376.1\|1796199_1796739_-	methyltransferase	NA	NA	NA	NA
VFI49378.1\|1796803_1797796_-	aspartate-ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	8.2e-53	40.1
VFI49380.1\|1797908_1798592_-	membrane protein	NA	NA	NA	NA
VFI49382.1\|1798647_1799388_-	spoU rRNA methylase family protein	NA	NA	NA	NA
VFI49384.1\|1799421_1799700_+	acylphosphate phosphohydrolase	NA	NA	NA	NA
VFI49386.1\|1799777_1800704_+	oxaA2	NA	NA	NA	NA
VFI49388.1\|1800778_1801573_-	pyruvate formate-lyase-activating enzyme	NA	NA	NA	NA
VFI49390.1\|1801698_1802949_-	diaminopimelate decarboxylase	NA	NA	NA	NA
VFI49392.1\|1803015_1803843_-	repressor of purine biosynthetic genes	NA	NA	NA	NA
VFI49394.1\|1804109_1805051_-	cmp-binding-factor 1	NA	NA	NA	NA
VFI49396.1\|1805040_1806297_-	competence-induced protein Ccs50	NA	NA	NA	NA
VFI49398.1\|1806298_1806961_-	thiamine pyrophosphokinase	NA	NA	NA	NA
VFI49400.1\|1806923_1807580_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
VFI49402.1\|1807590_1808469_-	ribosome-associated GTPase	NA	NA	NA	NA
VFI49404.1\|1808470_1809343_-	dimethyladenosine transferase	NA	NA	NA	NA
VFI49406.1\|1809473_1809782_-	Uncharacterised protein	NA	NA	NA	NA
VFI49408.1\|1809774_1810416_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.5e-26	36.0
VFI49410.1\|1810417_1812448_-	immunity protein	NA	NA	NA	NA
VFI49412.1\|1812524_1812821_-\|bacteriocin	bacteriocin, lactococcin 972 family	NA	NA	NA	NA
VFI49414.1\|1813140_1814040_-	transcriptional activator	NA	NA	NA	NA
VFI49416.1\|1814111_1814672_-	putative primase homolog	NA	NA	NA	NA
VFI49419.1\|1814671_1815445_-	TatD family deoxyribonuclease	NA	NA	NA	NA
VFI49421.1\|1815749_1816649_-	putative surface anchored protein (pseudogene)	NA	NA	NA	NA
VFI49423.1\|1816932_1817067_-	50S ribosomal protein L34	NA	NA	NA	NA
VFI49426.1\|1817211_1818426_-	putative aminotransferase AlaT	NA	NA	NA	NA
VFI49428.1\|1818581_1818875_-	Uncharacterised protein	NA	NA	NA	NA
VFI49430.1\|1819036_1819489_+	universal stress protein	NA	NA	NA	NA
VFI49433.1\|1819523_1820912_-	cof family protein	A0A0H3UZF4	Geobacillus_virus	9.7e-20	37.9
VFI49435.1\|1820977_1821940_+	L-asparaginase (L-asparagine amidohydrolase)	NA	NA	NA	NA
VFI49437.1\|1821968_1822172_-	chlorohydrolase	NA	NA	NA	NA
VFI49439.1\|1822235_1823246_-	catabolite control protein A	NA	NA	NA	NA
VFI49441.1\|1823669_1824269_-	response regulator	NA	NA	NA	NA
VFI49443.1\|1824269_1825367_-	histidine kinase	NA	NA	NA	NA
VFI49445.1\|1825366_1826104_-	multidrug ABC transporter permease	NA	NA	NA	NA
VFI49447.1\|1826105_1826990_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.9e-21	29.8
VFI49449.1\|1826976_1827171_-	Uncharacterised protein	NA	NA	NA	NA
VFI49452.1\|1827257_1827359_-	alanine aminotransferase	NA	NA	NA	NA
VFI49454.1\|1828010_1829303_+\|transposase	IS1167, transposase	A0A1S5SBP9	Streptococcus_phage	1.2e-242	98.6
VFI49457.1\|1829392_1830400_-	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
VFI49459.1\|1830619_1831579_-	puttaive FtsX-family transport protein	NA	NA	NA	NA
VFI49461.1\|1831664_1832003_-\|transposase	IS630-Spn1, transposase Orf2	NA	NA	NA	NA
VFI49463.1\|1832160_1832511_-\|transposase	IS630-Spn1, transposase Orf1	NA	NA	NA	NA

DBSCAN-SWA_19

1863138 : 1906582

Streptococcus_phage(98.44%)

head,tail,holin,terminase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI49535.1\|1863138_1863396_-	Uncharacterised protein	A0A126GGL1	Streptococcus_phage	1.4e-41	100.0
VFI49537.1\|1863666_1864623_-	autolysin	A0A1S5SB73	Streptococcus_phage	3.7e-143	99.1
VFI49539.1\|1864626_1864959_-\|holin	phage holin, LL-H family	A0A1S5SCF2	Streptococcus_phage	2.0e-43	100.0
VFI49541.1\|1864962_1865262_-	Protein of uncharacterised function (DUF2762)	A0A1S5S7P8	Streptococcus_phage	2.5e-45	100.0
VFI49543.1\|1865270_1865621_-	phage protein	X2KPI8	Streptococcus_phage	4.7e-64	100.0
VFI49545.1\|1865623_1865827_-	phage protein	A0A1S5SCH7	Streptococcus_phage	3.8e-26	100.0
VFI49547.1\|1865807_1865924_-	phage protein	A0A1S5SCF0	Streptococcus_phage	4.0e-12	100.0
VFI49549.1\|1865920_1872481_-	PblB	A0A1S5SCQ0	Streptococcus_phage	0.0e+00	84.5
VFI49551.1\|1872485_1872836_-	prophage protein	A0A1S5SCJ5	Streptococcus_phage	1.2e-62	100.0
VFI49554.1\|1872844_1876498_-	TMP repeat family	A0A1S5SC25	Streptococcus_phage	0.0e+00	99.1
VFI49556.1\|1876484_1876835_-	Uncharacterised protein	X2KU36	Streptococcus_phage	2.1e-56	100.0
VFI49559.1\|1877059_1877254_-	prophage protein	X2KUF7	Streptococcus_phage	6.7e-28	100.0
VFI49561.1\|1877258_1877672_-\|tail	major tail protein	X2L099	Streptococcus_phage	2.5e-72	100.0
VFI49563.1\|1877674_1878043_-	conserved structural protein, putative	X2KSZ9	Streptococcus_phage	9.0e-66	100.0
VFI49565.1\|1878039_1878555_-	Lj965 prophage protein	X2KPH9	Streptococcus_phage	2.7e-92	100.0
VFI49567.1\|1878529_1878868_-	Uncharacterised protein	A0A1S5SCH1	Streptococcus_phage	8.6e-47	100.0
VFI49569.1\|1878848_1879160_-\|head,tail	Phage gp6-like head-tail connector protein	X2KUF3	Streptococcus_phage	1.9e-48	100.0
VFI49571.1\|1879161_1879350_-	Uncharacterised protein	E8ZDV0	Streptococcus_phage	8.5e-28	100.0
VFI49573.1\|1879359_1880385_-	Carbohydrate-binding family V/XII	E8ZD37	Streptococcus_phage	6.6e-191	100.0
VFI49576.1\|1880407_1880917_-	phage scaffold protein	A0A141E1X5	Streptococcus_phage	3.1e-72	98.8
VFI49578.1\|1881062_1881275_-	phage protein	A0A1S5SCQ9	Streptococcus_phage	2.2e-32	100.0
VFI49580.1\|1881229_1881394_-	Uncharacterised protein	NA	NA	NA	NA
VFI49582.1\|1881415_1881703_-	Uncharacterised protein	A0A060QN60	Streptococcus_phage	3.2e-50	100.0
VFI49584.1\|1881745_1882159_-	metal dependent phosphohydrolase, HD region	A0A060QNR4	Streptococcus_phage	1.1e-67	100.0
VFI49586.1\|1882155_1882365_-	phage protein	A0A141E1P2	Streptococcus_phage	2.6e-33	100.0
VFI49588.1\|1882366_1883950_-\|head	phage putative head morphogenesis protein, SPP1 gp7 family	A0A1S5S801	Streptococcus_phage	4.2e-301	100.0
VFI49590.1\|1883912_1885382_-\|portal	phage portal protein, SPP1 family	A0A141E1P4	Streptococcus_phage	1.7e-277	99.4
VFI49592.1\|1885393_1886608_-\|terminase	phage terminase large subunit	A0A141E229	Streptococcus_phage	1.6e-236	100.0
VFI49594.1\|1886597_1887092_-\|terminase	putative small subunit of the terminase	A0A1S5SF14	Streptococcus_phage	5.4e-82	100.0
VFI49596.1\|1887552_1887957_-	phage protein	E8ZDG2	Streptococcus_phage	1.4e-67	100.0
VFI49598.1\|1888028_1888394_-	Uncharacterised protein	A0A141E232	Streptococcus_phage	4.2e-63	100.0
VFI49600.1\|1888390_1888711_-	Uncharacterised protein	E8ZDG4	Streptococcus_phage	7.6e-53	100.0
VFI49602.1\|1888707_1889148_-	YopX protein	A0A141E233	Streptococcus_phage	1.0e-79	100.0
VFI49604.1\|1889144_1889648_-	phage protein	E8ZDG6	Streptococcus_phage	2.2e-94	100.0
VFI49606.1\|1889649_1889967_-	gp24	E8ZDG7	Streptococcus_phage	6.0e-58	100.0
VFI49608.1\|1889991_1890174_-	phage protein	A0A141E1B5	Streptococcus_phage	9.1e-27	100.0
VFI49610.1\|1890189_1890621_-	holliday junction resolvase	E8ZD55	Streptococcus_phage	2.1e-77	100.0
VFI49612.1\|1890617_1890779_-	phage protein	E8ZDG9	Streptococcus_phage	4.3e-12	47.7
VFI49614.1\|1890792_1891002_-	Uncharacterised protein	E8ZD57	Streptococcus_phage	2.5e-36	100.0
VFI49616.1\|1891003_1891699_-	adenine-specific methyltransferase	E8ZD58	Streptococcus_phage	8.0e-132	100.0
VFI49618.1\|1891739_1891988_-	single-strand binding protein family	E8ZDH2	Streptococcus_phage	7.5e-40	100.0
VFI49620.1\|1891984_1892083_-	phage protein	A0A141E1Q6	Streptococcus_phage	2.8e-11	100.0
VFI49622.1\|1892082_1892418_-	Uncharacterised protein	A0A1S5SFR8	Streptococcus_phage	1.5e-59	100.0
VFI49624.1\|1892410_1892734_-	Uncharacterised protein	E8ZDH5	Streptococcus_phage	6.1e-58	100.0
VFI49626.1\|1892736_1892898_-	Uncharacterised protein	A0A141E242	Streptococcus_phage	7.7e-22	100.0
VFI49628.1\|1892900_1893941_-	phage protein	A0A1S5SFI4	Streptococcus_phage	1.8e-188	100.0
VFI49630.1\|1893950_1894715_-	phage protein RecT family	A0A1S5SFP4	Streptococcus_phage	5.0e-143	99.6
VFI49632.1\|1894726_1894957_-	Uncharacterised protein	A0A141E1R0	Streptococcus_phage	1.7e-33	100.0
VFI49634.1\|1894973_1895090_-	Uncharacterised protein	A0A1S5SFF0	Streptococcus_phage	4.1e-17	100.0
VFI49636.1\|1895076_1895220_-	phage protein	A0A1S5SA09	Streptococcus_phage	5.4e-19	100.0
VFI49638.1\|1895206_1895467_-	Uncharacterised protein	A0A060QNS3	Streptococcus_phage	3.3e-38	100.0
VFI49640.1\|1895459_1895666_-	Uncharacterised protein	E8ZDI1	Streptococcus_phage	6.4e-29	100.0
VFI49642.1\|1895665_1895827_-	Uncharacterised protein	E8ZDI2	Streptococcus_phage	6.3e-24	100.0
VFI49644.1\|1895887_1896106_-	Uncharacterised protein	A0A1S5S7L4	Streptococcus_phage	1.0e-16	67.2
VFI49646.1\|1896044_1896899_-	phage DNA replication protein	A0A060QN71	Streptococcus_phage	3.6e-158	100.0
VFI49648.1\|1896908_1897760_-	phage protein	A0A060QNS5	Streptococcus_phage	2.3e-149	100.0
VFI49651.1\|1897756_1897975_-	Cro/CI family phage transcriptional regulator	E8ZDI5	Streptococcus_phage	1.6e-33	100.0
VFI49653.1\|1898056_1898263_+	Uncharacterised protein	A0A1S5SFE1	Streptococcus_phage	1.8e-23	79.4
VFI49655.1\|1898174_1898465_-	Uncharacterised protein	A0A1S5SFE0	Streptococcus_phage	1.7e-43	90.6
VFI49657.1\|1899002_1899125_-	Uncharacterised protein	A0A060QNV8	Streptococcus_phage	2.2e-13	100.0
VFI49660.1\|1899198_1899474_-	Uncharacterised protein	A0A060QN73	Streptococcus_phage	5.9e-46	100.0
VFI49662.1\|1899648_1900455_+	cI repressor	E8ZDI9	Streptococcus_phage	1.4e-148	100.0
VFI49664.1\|1900456_1901221_+	phage protein	E8ZDJ0	Streptococcus_phage	3.7e-138	100.0
VFI49666.1\|1901499_1902945_+	site-specific recombinase/resolvase	A0A060QNW0	Streptococcus_phage	2.2e-277	100.0
VFI49668.1\|1903026_1903899_-	competence protein	NA	NA	NA	NA
VFI49670.1\|1903990_1904932_-	competence protein	NA	NA	NA	NA
VFI49672.1\|1905007_1905373_-	DNA binding protein	NA	NA	NA	NA
VFI49674.1\|1905523_1906582_-	alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.7e-14	26.8

DBSCAN-SWA_20

1935396 : 1993314

Bacillus_phage(30.0%)

transposase,tRNA,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI49725.1\|1935396_1935786_-\|transposase	transposase	NA	NA	NA	NA
VFI49727.1\|1935949_1936426_+	Uncharacterized conserved protein	A0A291ATU0	Pandoravirus	3.8e-16	36.6
VFI49729.1\|1936509_1937217_+	response regulator	W8CYM9	Bacillus_phage	1.4e-38	39.6
VFI49732.1\|1937217_1938549_+	histidine kinase PnpS	W8CYF6	Bacillus_phage	1.9e-33	34.9
VFI49734.1\|1938715_1939591_+	phosphate ABC transporter substrate-binding protein	NA	NA	NA	NA
VFI49736.1\|1939708_1940572_+	phosphate ABC transporter permeae PstC	NA	NA	NA	NA
VFI49738.1\|1940564_1941380_+	phosphate ABC transporter	NA	NA	NA	NA
VFI49740.1\|1941381_1942134_+	phosphate transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.3e-15	27.4
VFI49742.1\|1942148_1942799_+	phosphate transport system regulatory protein PhoU	NA	NA	NA	NA
VFI49744.1\|1942866_1943292_+\|transposase	transposase, IS1380-Spn1 related, truncation	NA	NA	NA	NA
VFI49746.1\|1943465_1943846_-	transcriptional regulator	NA	NA	NA	NA
VFI49748.1\|1944057_1945074_+	glycerol-3-phosphate dehydrogenase (NAD(P)+)	NA	NA	NA	NA
VFI49750.1\|1945095_1945995_+	UTP-glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	8.1e-76	50.7
VFI49752.1\|1946061_1946739_-	peptidase, S54	NA	NA	NA	NA
VFI49754.1\|1946722_1947262_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
VFI49756.1\|1947273_1948404_-	GlpG protein (membrane protein of glp regulon)	NA	NA	NA	NA
VFI49758.1\|1948471_1949170_-	2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase	NA	NA	NA	NA
VFI49760.1\|1949399_1950311_-	drug/metabolite transporter (DMT) superfamily permease	NA	NA	NA	NA
VFI49762.1\|1950375_1952841_-	penicillin-binding protein 1B	NA	NA	NA	NA
VFI49764.1\|1952982_1954239_+\|tRNA	tyrosine--tRNA ligase	A0A2C9CYK4	Yersinia_phage	2.5e-75	41.3
VFI49766.1\|1954316_1956380_-	P-type ATPase-metal/cation transporter	E4ZFI9	Streptococcus_phage	4.5e-53	26.0
VFI49768.1\|1956381_1956660_-	Uncharacterised protein	NA	NA	NA	NA
VFI49770.1\|1956811_1957660_+	23S_rRNA m1G745 methyltransferase	NA	NA	NA	NA
VFI49772.1\|1958282_1958855_+	membrane protein	NA	NA	NA	NA
VFI49774.1\|1959395_1959542_-	Uncharacterised protein	NA	NA	NA	NA
VFI49776.1\|1959899_1962158_-	maltodextrin phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	5.7e-09	37.5
VFI49778.1\|1962183_1963701_-	4-alpha-glucanotransferase (amylomaltase)	NA	NA	NA	NA
VFI49780.1\|1964250_1965522_+	maltose/maltodextrin ABC transporter maltose /maltodextrin-binding protein	NA	NA	NA	NA
VFI49782.1\|1965632_1966925_+	maltodextrin ABC transporter permease	NA	NA	NA	NA
VFI49784.1\|1966926_1967769_+	maltodextrin ABC transporter permease	NA	NA	NA	NA
VFI49786.1\|1968021_1968822_+	malA-protein	NA	NA	NA	NA
VFI49788.1\|1968831_1969818_+	maltose operon transcriptional repressor	NA	NA	NA	NA
VFI49790.1\|1969884_1970163_+	N-ethylammeline chlorohydrolase	NA	NA	NA	NA
VFI49792.1\|1970198_1971140_-	YitT family protein	NA	NA	NA	NA
VFI49794.1\|1971117_1972881_-\|tRNA	aspartyl-tRNA synthetase (aspartate-tRNA ligase)	A0A1V0SJ84	Klosneuvirus	5.0e-13	26.4
VFI49796.1\|1973031_1973235_-	chlorohydrolase	NA	NA	NA	NA
VFI49798.1\|1973276_1973507_-	excreted peptide	NA	NA	NA	NA
VFI49800.1\|1973524_1974166_-\|protease	caax amino protease family protein	NA	NA	NA	NA
VFI49802.1\|1974177_1974912_-	brp/Blh family beta-carotene 15,15'-monooxygenase	NA	NA	NA	NA
VFI49804.1\|1974914_1975112_-	Uncharacterised protein	NA	NA	NA	NA
VFI49806.1\|1975111_1975327_-	transcriptional regulator	NA	NA	NA	NA
VFI49808.1\|1975327_1975642_-	Uncharacterised protein	NA	NA	NA	NA
VFI49810.1\|1975979_1977269_-\|tRNA	histidyl-tRNA synthetase	NA	NA	NA	NA
VFI49812.1\|1977346_1978594_-	major facilitator superfamily permease	NA	NA	NA	NA
VFI49814.1\|1978784_1979636_-	transcriptional activator, Rgg/GadR/MutR family protein	NA	NA	NA	NA
VFI49816.1\|1979759_1980101_+	domain of uncharacterised function protein	NA	NA	NA	NA
VFI49818.1\|1980354_1982058_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
VFI49820.1\|1982290_1983223_-	transketolase c-terminal section	NA	NA	NA	NA
VFI49822.1\|1983219_1984077_-	transketolase n-terminal section	A0A2K9L6P9	Tupanvirus	4.2e-29	31.2
VFI49824.1\|1984080_1985427_-	PTS system, IIC component	NA	NA	NA	NA
VFI49827.1\|1985439_1985724_-	PTS system, IIB component	NA	NA	NA	NA
VFI49829.1\|1985727_1987758_-	transcriptional regulator, BglG family	NA	NA	NA	NA
VFI49832.1\|1987948_1988956_+	integral membrane protein	NA	NA	NA	NA
VFI49834.1\|1988958_1989159_+	Uncharacterised protein	NA	NA	NA	NA
VFI49836.1\|1989310_1989493_+	50S ribosomal protein L32	NA	NA	NA	NA
VFI49838.1\|1989508_1989658_+	LSU ribosomal protein L33p @ LSU ribosomal protein L33p, zinc-independent	NA	NA	NA	NA
VFI49840.1\|1990137_1992003_-\|holin	choline binding protein PcpA	NA	NA	NA	NA
VFI49842.1\|1992337_1992520_+\|transposase	degenerate transposase	NA	NA	NA	NA
VFI49844.1\|1992464_1992899_+	mobile genetic element	NA	NA	NA	NA
VFI49846.1\|1992924_1993314_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_21

2054814 : 2092886

Streptococcus_phage(50.0%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VFI49941.1\|2054814_2057508_-\|holin	choline-binding surface protein A	NA	NA	NA	NA
VFI49943.1\|2057586_2058114_-	membrane protein	NA	NA	NA	NA
VFI49945.1\|2058208_2059540_-	signal transduction histidine kinase	NA	NA	NA	NA
VFI49947.1\|2059536_2060190_-	DNA-binding response regulator	NA	NA	NA	NA
VFI49949.1\|2060831_2063264_-\|protease	ATP-dependent Clp protease, ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	1.4e-127	40.6
VFI49951.1\|2063265_2063724_-	CtsR family transcriptional regulator	NA	NA	NA	NA
VFI49953.1\|2063842_2064571_-	nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.0e-28	36.2
VFI49955.1\|2064570_2065578_-	ABC transportersubstrate-binding protein, nitrate/sulfonate/bicarbonate transport	NA	NA	NA	NA
VFI49957.1\|2065616_2066375_-	ABC transporter permease, nitrate/sulfonate/bicarbonate transport	NA	NA	NA	NA
VFI49959.1\|2066337_2066628_-	Uncharacterized conserved protein	NA	NA	NA	NA
VFI49961.1\|2066875_2068222_-\|holin	choline binding protein D	NA	NA	NA	NA
VFI49963.1\|2068310_2068577_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VFI49965.1\|2068578_2069931_-	DNA replication protein DnaC	A0A1P8VVQ6	Streptococcus_phage	4.9e-149	61.3
VFI49967.1\|2069974_2070427_-	50S ribosomal protein L9	NA	NA	NA	NA
VFI49969.1\|2070423_2072397_-	DHH family protein	NA	NA	NA	NA
VFI49972.1\|2072532_2073081_-	ribosome-associated protein	NA	NA	NA	NA
VFI49974.1\|2073160_2073823_-	involved in transformation	NA	NA	NA	NA
VFI49976.1\|2073819_2075118_-	helicase ComFA	A0A1X9I5S6	Streptococcus_phage	7.9e-165	66.4
VFI49978.1\|2075173_2075809_+	Xaa-Pro dipeptidase	A0A1X9I5T8	Streptococcus_phage	1.7e-75	71.0
VFI49980.1\|2076057_2076978_+	cysteine synthase	A0A1X9I5K7	Streptococcus_phage	1.3e-137	80.7
VFI49982.1\|2077174_2077573_-\|transposase	transposase	NA	NA	NA	NA
VFI49984.1\|2078012_2078336_-\|transposase	transposase, ISSmi4	NA	NA	NA	NA
VFI49987.1\|2078581_2079622_-	elongation factor Ts	NA	NA	NA	NA
VFI49989.1\|2079700_2080480_-	30S ribosomal protein S2	NA	NA	NA	NA
VFI49991.1\|2080702_2081881_-	CHAP domain-containing protein	NA	NA	NA	NA
VFI49993.1\|2081974_2082469_-	rod shape-determining protein MreD	NA	NA	NA	NA
VFI49995.1\|2082468_2083287_-	cell shape determining protein MreC	NA	NA	NA	NA
VFI49997.1\|2083345_2084140_-	ABC transporter permease, cobalt transport	NA	NA	NA	NA
VFI49999.1\|2084132_2084972_-	cobalt ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-15	32.6
VFI50001.1\|2084956_2085784_-	ABCtransporter ATP-binding protein cobalt transport	G9BWD6	Planktothrix_phage	2.8e-22	32.9
VFI50003.1\|2085780_2086326_-	phosphatidylglycerophosphate synthase	NA	NA	NA	NA
VFI50004.1\|2086336_2087158_-	transcriptional regulation protein	NA	NA	NA	NA
VFI50005.1\|2087199_2088483_-\|protease	zinc-dependent protease	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	8.4e-18	30.0
VFI50006.1\|2088479_2089730_-\|protease	zinc-dependent protease	A0A1X9I714	Streptococcus_phage	2.7e-93	42.3
VFI50007.1\|2089888_2090257_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	57.3
VFI50008.1\|2090259_2091357_+	recombination protein recF	NA	NA	NA	NA
VFI50009.1\|2091407_2092886_-	inosine-5-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	40.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage